LOCUS       DACBYO010000001        78572 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.001, whole genome shotgun sequence.
ACCESSION   DACBYO010000001 DACBYO010000000
VERSION     DACBYO010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 78572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.001"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(65..730)
                     /locus_tag="IVD26_000001"
     CDS             complement(65..730)
                     /locus_tag="IVD26_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078018.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(877..1482)
                     /gene="dhaL"
                     /locus_tag="IVD26_000002"
     CDS             complement(877..1482)
                     /gene="dhaL"
                     /locus_tag="IVD26_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAP6078019.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(1510..2493)
                     /gene="dhaK"
                     /locus_tag="IVD26_000003"
     CDS             complement(1510..2493)
                     /gene="dhaK"
                     /locus_tag="IVD26_000003"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAP6078020.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(2495..2890)
                     /gene="dhaM"
                     /locus_tag="IVD26_000004"
     CDS             complement(2495..2890)
                     /gene="dhaM"
                     /locus_tag="IVD26_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAP6078021.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            3044..3364
                     /locus_tag="IVD26_000005"
     CDS             3044..3364
                     /locus_tag="IVD26_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAP6078022.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(3476..4345)
                     /locus_tag="IVD26_000006"
     CDS             complement(3476..4345)
                     /locus_tag="IVD26_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP6078023.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(4441..5745)
                     /locus_tag="IVD26_000007"
     CDS             complement(4441..5745)
                     /locus_tag="IVD26_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP6078024.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(5742..6251)
                     /locus_tag="IVD26_000008"
     CDS             complement(5742..6251)
                     /locus_tag="IVD26_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078025.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(6426..8561)
                     /locus_tag="IVD26_000009"
     CDS             complement(6426..8561)
                     /locus_tag="IVD26_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6078026.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(8644..10299)
                     /locus_tag="IVD26_000010"
     CDS             complement(8644..10299)
                     /locus_tag="IVD26_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP6078027.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(10301..10615)
                     /locus_tag="IVD26_000011"
     CDS             complement(10301..10615)
                     /locus_tag="IVD26_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP6078028.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            10785..11045
                     /locus_tag="IVD26_000012"
     CDS             10785..11045
                     /locus_tag="IVD26_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAP6078029.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            11059..11373
                     /locus_tag="IVD26_000013"
     CDS             11059..11373
                     /locus_tag="IVD26_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAP6078030.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(12103..12657)
                     /locus_tag="IVD26_000014"
     CDS             complement(12103..12657)
                     /locus_tag="IVD26_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAP6078031.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(12783..14712)
                     /locus_tag="IVD26_000015"
                     /pseudo
     CDS             complement(12783..14712)
                     /locus_tag="IVD26_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(15018..15734)
                     /locus_tag="IVD26_000016"
     CDS             complement(15018..15734)
                     /locus_tag="IVD26_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAP6078032.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(15735..17558)
                     /gene="glpO"
                     /locus_tag="IVD26_000017"
     CDS             complement(15735..17558)
                     /gene="glpO"
                     /locus_tag="IVD26_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAP6078033.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(17572..19068)
                     /gene="glpK"
                     /locus_tag="IVD26_000018"
     CDS             complement(17572..19068)
                     /gene="glpK"
                     /locus_tag="IVD26_000018"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAP6078034.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFREKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(19204..20664)
                     /locus_tag="IVD26_000019"
     CDS             complement(19204..20664)
                     /locus_tag="IVD26_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6078035.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(20654..21949)
                     /locus_tag="IVD26_000020"
     CDS             complement(20654..21949)
                     /locus_tag="IVD26_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP6078036.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(22281..22958)
                     /locus_tag="IVD26_000021"
     CDS             complement(22281..22958)
                     /locus_tag="IVD26_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAP6078037.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(22988..24079)
                     /locus_tag="IVD26_000022"
     CDS             complement(22988..24079)
                     /locus_tag="IVD26_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAP6078038.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(24180..24614)
                     /locus_tag="IVD26_000023"
     CDS             complement(24180..24614)
                     /locus_tag="IVD26_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6078039.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(25198..26655)
                     /gene="ascB"
                     /locus_tag="IVD26_000024"
     CDS             complement(25198..26655)
                     /gene="ascB"
                     /locus_tag="IVD26_000024"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP6078040.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(26652..28547)
                     /locus_tag="IVD26_000025"
     CDS             complement(26652..28547)
                     /locus_tag="IVD26_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6078041.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(28605..30380)
                     /locus_tag="IVD26_000026"
     CDS             complement(28605..30380)
                     /locus_tag="IVD26_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP6078042.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(30430..31926)
                     /locus_tag="IVD26_000027"
     CDS             complement(30430..31926)
                     /locus_tag="IVD26_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP6078043.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(32120..33742)
                     /locus_tag="IVD26_000028"
     CDS             complement(32120..33742)
                     /locus_tag="IVD26_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP6078044.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(34070..35383)
                     /locus_tag="IVD26_000029"
     CDS             complement(34070..35383)
                     /locus_tag="IVD26_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP6078045.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(35628..35852)
                     /locus_tag="IVD26_000030"
     CDS             complement(35628..35852)
                     /locus_tag="IVD26_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078046.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(35872..36240)
                     /locus_tag="IVD26_000031"
     CDS             complement(35872..36240)
                     /locus_tag="IVD26_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP6078047.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(36436..37146)
                     /locus_tag="IVD26_000032"
     CDS             complement(36436..37146)
                     /locus_tag="IVD26_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078048.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(37164..37661)
                     /locus_tag="IVD26_000033"
     CDS             complement(37164..37661)
                     /locus_tag="IVD26_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6078049.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(37698..38150)
                     /locus_tag="IVD26_000034"
     CDS             complement(37698..38150)
                     /locus_tag="IVD26_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6078050.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(38285..38890)
                     /locus_tag="IVD26_000035"
     CDS             complement(38285..38890)
                     /locus_tag="IVD26_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAP6078051.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(39340..39960)
                     /locus_tag="IVD26_000036"
     CDS             complement(39340..39960)
                     /locus_tag="IVD26_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6078052.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(39962..40831)
                     /locus_tag="IVD26_000037"
     CDS             complement(39962..40831)
                     /locus_tag="IVD26_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAP6078053.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(40854..41261)
                     /locus_tag="IVD26_000038"
     CDS             complement(40854..41261)
                     /locus_tag="IVD26_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP6078054.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(41280..42569)
                     /locus_tag="IVD26_000039"
     CDS             complement(41280..42569)
                     /locus_tag="IVD26_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6078055.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(42596..42898)
                     /locus_tag="IVD26_000040"
     CDS             complement(42596..42898)
                     /locus_tag="IVD26_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6078056.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(42923..45016)
                     /locus_tag="IVD26_000041"
     CDS             complement(42923..45016)
                     /locus_tag="IVD26_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP6078057.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(45505..46269)
                     /locus_tag="IVD26_000042"
     CDS             complement(45505..46269)
                     /locus_tag="IVD26_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAP6078058.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(46380..47249)
                     /gene="mdcB"
                     /locus_tag="IVD26_000043"
     CDS             complement(46380..47249)
                     /gene="mdcB"
                     /locus_tag="IVD26_000043"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAP6078059.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(47274..48350)
                     /locus_tag="IVD26_000044"
     CDS             complement(47274..48350)
                     /locus_tag="IVD26_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAP6078060.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(48374..48967)
                     /locus_tag="IVD26_000045"
     CDS             complement(48374..48967)
                     /locus_tag="IVD26_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAP6078061.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(48971..50647)
                     /gene="mdcD"
                     /locus_tag="IVD26_000046"
     CDS             complement(48971..50647)
                     /gene="mdcD"
                     /locus_tag="IVD26_000046"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAP6078062.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(50637..50936)
                     /locus_tag="IVD26_000047"
     CDS             complement(50637..50936)
                     /locus_tag="IVD26_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAP6078063.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(51038..52684)
                     /gene="mdcA"
                     /locus_tag="IVD26_000048"
     CDS             complement(51038..52684)
                     /gene="mdcA"
                     /locus_tag="IVD26_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAP6078064.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(52691..53602)
                     /locus_tag="IVD26_000049"
     CDS             complement(52691..53602)
                     /locus_tag="IVD26_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP6078065.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            53722..54579
                     /locus_tag="IVD26_000050"
     CDS             53722..54579
                     /locus_tag="IVD26_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6078066.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(54766..55128)
                     /locus_tag="IVD26_000051"
     CDS             complement(54766..55128)
                     /locus_tag="IVD26_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078067.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            55474..56913
                     /locus_tag="IVD26_000052"
     CDS             55474..56913
                     /locus_tag="IVD26_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP6078068.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(56920..59472)
                     /locus_tag="IVD26_000053"
     CDS             complement(56920..59472)
                     /locus_tag="IVD26_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAP6078069.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(59586..60917)
                     /locus_tag="IVD26_000054"
     CDS             complement(59586..60917)
                     /locus_tag="IVD26_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6078070.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(60883..62361)
                     /locus_tag="IVD26_000055"
     CDS             complement(60883..62361)
                     /locus_tag="IVD26_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6078071.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(62666..64501)
                     /gene="tdc"
                     /locus_tag="IVD26_000056"
     CDS             complement(62666..64501)
                     /gene="tdc"
                     /locus_tag="IVD26_000056"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAP6078072.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            64971..66398
                     /locus_tag="IVD26_000057"
     CDS             64971..66398
                     /locus_tag="IVD26_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP6078073.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(66490..66855)
                     /locus_tag="IVD26_000058"
     CDS             complement(66490..66855)
                     /locus_tag="IVD26_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAP6078074.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(66852..67217)
                     /locus_tag="IVD26_000059"
     CDS             complement(66852..67217)
                     /locus_tag="IVD26_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAP6078075.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(67409..67657)
                     /locus_tag="IVD26_000060"
     CDS             complement(67409..67657)
                     /locus_tag="IVD26_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078076.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            67656..67784
                     /locus_tag="IVD26_000061"
     CDS             67656..67784
                     /locus_tag="IVD26_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAP6078077.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            67841..69535
                     /locus_tag="IVD26_000062"
     CDS             67841..69535
                     /locus_tag="IVD26_000062"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAP6078078.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            69539..69658
                     /locus_tag="IVD26_000063"
                     /pseudo
     CDS             69539..69658
                     /locus_tag="IVD26_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            69740..69931
                     /locus_tag="IVD26_000064"
     CDS             69740..69931
                     /locus_tag="IVD26_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078079.1"
                     /translation="MDLLPQMQAFEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDL
                     LPQMQAFEHRLPRGYEKGV"
     gene            70309..71442
                     /locus_tag="IVD26_000065"
     CDS             70309..71442
                     /locus_tag="IVD26_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAP6078080.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            71473..71793
                     /locus_tag="IVD26_000066"
     CDS             71473..71793
                     /locus_tag="IVD26_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078081.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(71822..72286)
                     /locus_tag="IVD26_000067"
     CDS             complement(71822..72286)
                     /locus_tag="IVD26_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6078082.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(72417..73670)
                     /locus_tag="IVD26_000068"
     CDS             complement(72417..73670)
                     /locus_tag="IVD26_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6078083.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(73699..74016)
                     /locus_tag="IVD26_000069"
     CDS             complement(73699..74016)
                     /locus_tag="IVD26_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP6078084.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(74042..74362)
                     /locus_tag="IVD26_000070"
     CDS             complement(74042..74362)
                     /locus_tag="IVD26_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6078085.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(74826..76241)
                     /locus_tag="IVD26_000071"
     CDS             complement(74826..76241)
                     /locus_tag="IVD26_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP6078086.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(76258..77574)
                     /locus_tag="IVD26_000072"
     CDS             complement(76258..77574)
                     /locus_tag="IVD26_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6078087.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(77724..78422)
                     /locus_tag="IVD26_000073"
     CDS             complement(77724..78422)
                     /locus_tag="IVD26_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAP6078088.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT        22847 a        16684 c        13342 g        25699 t
ORIGIN      
        1 aaacaaacct tcactcgcaa gccgagagta aggtttgttt ttcgcattgc ttatttcgtg
       61 ttgtctattg aaatttttcc gcacctagct tttgatatag tggtgctagt tcttgtaagg
      121 tttcagcggt tatttgctca acgtgttcga tttcttgcgg atagaagaat agtttaccca
      181 tttgaaaggt tcggtctctc atcgcttttt tcaactcttc ttgtttcttt gtatcggaca
      241 aatagtcaga caaagctaag tggtcgtcaa gttcatgttc tggttgcggc catatgtaat
      301 aatccttgat atcgactgtt ttgctccact ctttcagtat cgcaagcaac tggttatacg
      361 ctgcaatgct accatatcgt tcttcgcttt tataatgttg gtacatcaaa tagatttggt
      421 attgtttttg attcaacaaa actgctagac aggcattctc gtcttgacga gattcgcttc
      481 ggtacgcgct ccaaaaatga ctgcgtaaat tccagccatt cgtccagctt tcgattttag
      541 gtttgctcat gccgtacata tcaggcaaaa gtgcagctgt ctggagctga atctctttcc
      601 atttttgcca gtgttcttta tattctttct tgatttgttc aatcttatct gttggatggc
      661 tctctttgag ctgtttgaat gcgtagattg gtcgatcaaa caactgataa tctgattttc
      721 caagttccat tgtttcgcct ctttccgtta tcttttgtat tctacctgaa ttttgcgata
      781 tggacaaata gaggttgtga aaaagctgtt ctgcatcaag tcataagaac agccaaacaa
      841 aaaactgcga tgagcatcac cgcagtttta ttgaacttaa ggttgattga tcacatctaa
      901 aagcgttgaa aataaaatgg cactagaagc agctcctggg tcgatatgtc cgattgcacg
      961 ctctcctaga taggaagctc gtcctttttt agctaccaag actttggtgt gttcttttgc
     1021 ctggtcaatg atttcttttg ttaaattccc tgccttcaat gcctctgtga ctggcagcca
     1081 aacatctaac atcgttttat cgtcagcttc tgcctttcct cggctttgaa tacccgctgt
     1141 tccctgctcg atcacttcgc ctaatttttc ttgagaatca atagaatcga cctcttttgt
     1201 cgctttcatc atgttcatga atgcagatcc gtataacgga ccagaagccc caccgacttt
     1261 cgatatcatc gccatagaga atactttgaa tgtatcgctg attgtttcag gatgatcggc
     1321 ttgaaaagct tcttcataag ctgaaacccc tcttcccatg ttatttccat ggtctccatc
     1381 gccaatcggg gtatctagat cactgagata ttgtttgttc tgattgattg cctctgcaaa
     1441 ttgcgtgagc cattcttgga tttcttgaac ggttagtttc atattatcac ccttttatct
     1501 tgagattttt taccatgaaa tcgtctgtac attgctttct aaagaatctt tccattgtgt
     1561 ctccgtcaag tcgatcagtg ttagagaaag accttgcata tctagtgagg tcataaaatt
     1621 accgactttt cggaaaacta cattgacgcc tctttcttcc aacagagcta aaacatcatt
     1681 catgaacacg aactgttcca tcaaaggcgt cccgcccatt ccgttgacta gtacacctgc
     1741 ttcttttggt aaattcgagt aatcatctaa aatcttagta acaagttcct ttgccagtac
     1801 tttagaaggc tgcatctttt ctcgacgata gcctggctca ccgtggatac caacaccata
     1861 ctcgatctca tcttctccta gttcgaatcc tggtttccct acttctggta cagttgctgc
     1921 tcgaagcgct agaccgatcg tcttagttgc ctgtacgacc ttttctccca gttctttcaa
     1981 ctcagctagg gaagcaccgt ttcttgctgc atcgcccacg attttgtgta caaggacagt
     2041 acctgcaact ccgcgttttc cagcagtata cgtactattt tcaacggcga tatcatcatc
     2101 tacgatcaca ctttctactt caatatcgtc catagcagct aattcctttg ccatatcgaa
     2161 gttcaatgca tcccctgtat aattcttaac gatcagcaaa actccttttc cactatcggc
     2221 ttccttaata gccgtctgaa tctgatctgg agttggagaa gtaaacacat caccaagcac
     2281 cgctgcactt aacatccctt cccctacaaa cccggcatgg gatggttcat gtccgcttcc
     2341 tccaccagaa accaaaccaa cttgttccgc tttctgattc ttggctacaa cacgggaaga
     2401 ttctacacga tgaacaagtt ctggatagct ttttactaat ccttccagca tttcttcgac
     2461 aatattgctt ggatcattca tgattttttt caatttattc ccatcctttc tttccggcat
     2521 tttgtgcttc tgttaagatt tgctgagtat catctgttat accggcagtg atggctgctg
     2581 caaaagctcc ttccactaaa ggcgcatcca ccagatgata acgttgctgc tgctcttctt
     2641 ccaacatgtc ttttgccagt tccgagttca ataccgcgct accgatatcc gcaaaaacaa
     2701 aataactagc tgcatcgctt gattcattga ctgcttctac gattttcatc gggtctgatc
     2761 cgatctcgcc atttattccg ccgagagaaa aaatttgcac ctcttcggat ttttgcatct
     2821 gctcaatcat ttctttaata ccatctgtta ctttttgact atgagaaata agcaaaatac
     2881 tttttttcac aagaatcttc ctttctttta catagttgct aacgattggt ttcgctttca
     2941 ttaatgaaca attcaagtat ataataaatt tctaattttg ggaaaatatg tgtagtgctt
     3001 cttgaagttt gttatacttt aattaaaaga gaggagtgat cgaatgatta caacaacaac
     3061 gaacagtgta gagggaaaag ccgtagtagc ttataaaggg atcgtttttg gtgaggtcat
     3121 tactgggatc catgcattta aagacttgga ggcggggttg cgaaatatct ttggcggccg
     3181 ctcaaaaagc tatgaaaacg aactaatggg tgcaagagaa gaagcacttg ccgaaatggc
     3241 cgaacgtgca aaagcattag gagctgatgc gatcattggc gtaaaaatgg actatgaagt
     3301 attaggcagc gacaatggca tgctgatggt cacatgtagt ggaacagctg tctccacgag
     3361 ataagtaggg gacatctgtt ttaataacta aagagagatg ggacatgtag tggcactcaa
     3421 gaattagatt tttcagtcta acttcgaggt actctacctt cccatcctct cttttttatt
     3481 tctttttgcg gatgattccg taagctgctg cgactaacac acccgcccct gctaaggaat
     3541 aactgacaga agctgttttt tcatttgttt ttggcaaagt ctgacttgtt gatttggatg
     3601 gctctgtcgt ttgctgaact gtttctgtcg tgcttccaga ggtcactgat ttttctcctg
     3661 ccgaatgcaa aatatctttt attcgttgga aactagctgc taagtcagct ttttttgctt
     3721 caaaatcatt agcaactgtt tgtgcttcgc tgatctttcc gtggattgct tgactggccg
     3781 ctgtgatatc cgcttgagtt tgacttagct ttccagaagc tgtttgagca acctgattta
     3841 attgctgatt gaattctttt gcttgttgga tcttcccgtc aagatctgtt tggacagctt
     3901 ccgcttttgc tttcgcttcg gcaagctttt tctcaagttg tgcacggtca tttcccactt
     3961 tatttttaag atcagctaaa tcttgatcga ttgctgcttg gtcttctttc aatttgtttt
     4021 ttgcagcttc taatgcttct tcgagttctt ttcttttatt ttccaagtct tgcaaatgat
     4081 cgatttggtc agaagaggta gaactattta ttgatgtatc ttctgaagat gaaatcgttt
     4141 ctcctgaatt atctgtcggt acattggaag tcatttctgt ttccgaggca ccgttttcag
     4201 caccagaaga gcttatggtt gttgaaggtt ctgtttgagc aggttcagaa gtttccgcaa
     4261 aagctgtctg tcccaataag aaaatactgg aaacagcaat tggccagatt aacggcttca
     4321 ttcttttttt catcactttt cccatcctta ctacttttta actaatttct tattataagc
     4381 aaaaatgttt ggaagaacca taaacacaac aggctgtttg tctaaaaaac ggtgcatctt
     4441 ttattttttt gtacgttccg ggcttttcca tgtcccgctt ccataaccta aaatcgtttt
     4501 gactgctgga atgaaagtcg tcacgatcgt tatcgcgttc actatccaga acaaaagcat
     4561 atatagtggt gcgaaaagaa ggtatttcaa ttttcttcgt cgatcatcta caatcagcga
     4621 agctagcaac tggaaaaatc ctgcgaccat ttcaaagcag atgaacacaa aactgaatgt
     4681 aaaagtaata taaatctgtt cgtagtttcc ttgatataca taatgcccga ttaatccagc
     4741 aaaaagaact acggaaatac aaaagaatat tgaccagaca atactcaatg tttgatcaat
     4801 gaagatgatc gttcttccaa tatgtttaaa aggatggagc atcacttttt tgaaattcgt
     4861 cagccagact tctgttccac cttttgccca acgttttctg tgtcgatata gcatcttcaa
     4921 cgtcacaggt acttccatga aaaagataat ctcaggagca aaaacagata accagtcatt
     4981 taactgatga tcccaagcaa tactgatgtc ttctgtcgct cgatcttgtc tgaatccgcc
     5041 cacatcgatc aaggcttctt ttcgatacat cgtatttgct ccactgtacg cataaagacc
     5101 accgaaaaca gctgactgtg ttcgtttaat gatgcccacg atacttgaga attcaaccgt
     5161 ttgagatttt gcaatcaatt tggtacgatt ttggacatcc atatttgcag tgaccgcagc
     5221 aatatgtctt gcaccagggc gaatgaaata attcacatac ctaatcagtg catctggctc
     5281 cggtaccgtg tctgcatcat tgcttaaaat caatttccct tttgcaaagg caagtccgat
     5341 attaaacgcg tgggcttttc ctttattttt ttcgatccga accacacgaa gattagcgta
     5401 ttttttcatc agtctagcta atatttctgg tgtttggtcc gttgaaccat cgtctgtcac
     5461 taatacctca tagttgtgat aattcaattt cgtcatcaaa tactcgattg tatattcgat
     5521 cacaatttct tcattatggg ctggcaccat gatcgtgatg aacggttcga cactcaaggg
     5581 aacatctacc cattcttttt gcttatgttt gtataaaaac acataacacc agacaccaat
     5641 aaaccataca aatccgccta aaatcggata agaaacgaga aaaaaataca taatagacaa
     5701 acaagtatct aagaataaat tacctgtatg ggtgattgag atcatttcag ttccacccca
     5761 ttttctttat acaaatctgc aatgaatgtc gtatctagat ttttctcttc ggagacagaa
     5821 taaaaacgga ccgtttctct ctcttctttt gttccaaaac gttccgtata cacttcttca
     5881 agtaattctt gtcttttttt caatttttca tcttcatatt caaaagattt atttactttt
     5941 ttgtatagat ttcgattgtt ccacctagtc aatacaaatg aggtaatcag gaaactgaaa
     6001 aaaatcaata caaaaaagcc gattaagaaa tacagcattt tcttttctga taaaaaagcg
     6061 tacaaggaaa aatccttggc tctttctggt ctcgttaatg ggaaaaagac ccatataaaa
     6121 ggaagaacaa cgatcatcca tcctaaaaga gccactaacg tttgccaaat ctttaaccag
     6181 taattacctt ttgaaaaata cttatctttc accaaaattg atgcaacttc ttctcttgtt
     6241 acttttttca tatcctcacc tcacgttttt ttgttacgac gtaggagttt accatacatt
     6301 tcatttcttt tcacataaag tgttcctaaa tttttcctaa gaaaaagaac aaaacatttc
     6361 tcatcagcaa atgaaaaata ttttgttctt tttatcagtt gttcttttta ttttttatct
     6421 cttaattatg ttgctctttc caatacgaca atgcttttca ttcctctaga tatcgccgtg
     6481 tacatttgtc tgcgtcttct ttgctcatct ccatcgtttt caaatggata taagattaca
     6541 tgatcaaatt ccagtccttt tgctagactc aaaggaatga tttggcagtt ttctaatcca
     6601 tatgaatttt ttttaatcga ttcttgtagc gtttgggttt cctcttctgt ttgggtgata
     6661 actgccgctt tttctccttt tagagaaacc aaaatctcag ctagtatttt caacaattct
     6721 tcagaggatc gaaaagagcg gtattcgggt tcttttcctt gcggtcggat cgatacgatg
     6781 tcgatcttct cttgatccac agcataggtt ttgaaaagct ctgtgattgc tccgctagaa
     6841 cggtaactat ttctaagatc ataccgatgg atcggcagat ggtagtcgtc gaaacaacgc
     6901 ataatatcag caaaagtagt ggaagaatta aagattgcct gattctcgtc acctactaaa
     6961 gtaaagtgag tttttggaaa taattcgatc aatagaccta attgtgccag ggtataatct
     7021 tgtacttcat caatcaatag atagcgaaat gctggtacat ttaccttttc aacaagtaaa
     7081 tgacgaatag ctaatataat gactgcttca tcaacagtac gtgtgggttg ccaagcataa
     7141 gctgagccat atcgtttttc ataaattctt tcaaacaact gatgctcatc cacccatgcc
     7201 atttcttcga tttgtctggt tatttttcga tatttttttt gtaaaagttt ccttgcataa
     7261 gctacaatac tttgttccga atcatcagaa atcaatttac cgaataattc caactgccta
     7321 tcttctgtca acgagagtac ctgattctgc acagcaggac tttttgcttg tttcaaaaga
     7381 tgattcttcc attcgctcat cagtgccttt ttcgttgctt gaagcctatc gatcaattta
     7441 ggatgagcag gaactttctc atatattttt tcgatcgttt ttttagaaag gactgttttt
     7501 ccatttttag taagtccacg gataaaattc ggatgatcta aaaacaaagg atctgattgt
     7561 tttagattat cgataaactt tttgctacgc aaacgttctg tctgctccga tacattttct
     7621 cccgtgatac gtttgaaata agcctcttca ccttctattt cctctgctga aagctgtgaa
     7681 accagctgta tgatggttag attcagtgga tttctttcac ctaatgatgg taggacattc
     7741 gaaatatagt cgataaaccg atgattaggt gatagaatca gcaagtcatc ggatgtcatc
     7801 gtatctcgat ataaatagag cagatacgca atacgctgca tgatagcaga ggttttacca
     7861 cttcctgcta cgccatttac caagatattt tgacttttca catcccgaat gattgtgttt
     7921 tgttccgatt ggatcgtagc agtgatagcc ttcatttcat tggtctcatc ttggcctaag
     7981 acttctaata atacgtcatc ttgaatagct acagacgtat caaaaaactt gaccaaacga
     8041 tctctttcca aaagaaattg tcgtctttct ttaataaccg tatcgatttt attttgacga
     8101 accgtataag aagatggacc aatcatgtta ttgtaaaaaa gttcggcaat tggtgaacgc
     8161 caatcataaa caagattttc atctgcatca tctgtgaaat ttgctgtacc gatataaaag
     8221 gattcttttg gctcattatc cagaaagtct acaacgactt ttccaaagta gggacttttc
     8281 aataaacgtt cgatctttgc tagctgattt tctgcgtttt tctgtttgat attcatctga
     8341 tcgatttctc tatttttcat ttcaatcatc gaaaaagtat ccaggttatc taagtaactg
     8401 tcaaaattca atcgaagctc gccagccatt tctttcaacg actggtttcc ttctattttt
     8461 gccgtatcca tcgattcccg cagttcgttt tttttatcaa ttagcttttg atacacgttc
     8521 ttcagatatg cttcttctaa ctgtttttgt gtgttgacca tacacattct cctctttttt
     8581 taaagtggtg gaaccgatta gtttacctct tttaagagtc gaatgcaagc tttttaacga
     8641 gtatcatttg ttaggatata tcagttcttc aggtcggaca gtttgatata aagaaaatgc
     8701 accatcaagg ttttttacgt ggtagccaga ctgcttcaag attctttccg ctagatagct
     8761 acgtaatccg ctatgacagc tgacgatata ttcttgttgg ctgtctaatt catttaatcg
     8821 gtcccgaagt tcattcaaag ggatatgttt ggcttccttg aatttgccct tttccaattc
     8881 ttctgctgtt cgcacatcta ataaaatttt tccttttgct agttctgtcg gcaattcatg
     8941 ccattgtacg gtttcactaa gcccttctgc aatgttcatt gctgcatatc ctagcatgtt
     9001 tactggatct ttggctgagc caaatggcgg tgcatacgtc aattctaatt ccggtaaatc
     9061 gaagatcgtc aaatgccctt tgattgctgt tgctaaaata tcgatccgtt tatccacacc
     9121 ttttgcccca acaccttgtg caccataaat ctcgccagtc tctggatgga agatcaactt
     9181 cagtaaaata tctgttgctt ctggataata gcttgcatga tcttttcctg atacatgaat
     9241 gacttcaaaa gacagttcgt tttctttggc tgttctttca cttaaaccgg tggatgcggc
     9301 agtcattcca aacgttcgta taattgctgt tccaataccg ccttgatttc ttcgagaaat
     9361 tccggaaatc gtgtccgcaa cttgtctacc ttgacgattg gctggtgaag caagagaaat
     9421 aagtgcatct tttccagtga tttgctgttt tacaacgata gcatccccca ccgcataaat
     9481 atcaggaata ttcgtttgat aacgttcgtc tactaggata cccccgcgta tgcctaattc
     9541 gattccagcg gtcactgcta gctggttatc aggacgaaca ccaatggata aaataactaa
     9601 atcagcaggg atggtacgcc catcatccag tcgcaatcgt ttcccgtggt cttcaaatcc
     9661 agcgacagca tgagaagtaa tcacttctac tccttgatga gacaattctt tttctataaa
     9721 agctgccatt tcttcatcca gtgttggaag aatatgtggt gcttgttcga tcaccatgac
     9781 ttctaaacct cttcttttta ggttttctgc catttccaat ccgatgaatc ctgcaccaac
     9841 gatcacggca cgctttggct gtttttctaa tgcatgcatc actttatcga tatctggtac
     9901 atttctaata gaaaaaacat tgtcggcttc tgttatccct ggaatcgatg gaacaactgg
     9961 ttttgcacca ggagataaaa ccaatgcatc gtactgttca atgtgttttt gaccctcatg
    10021 tacgacttct accgttttgt tttcgggaaa gatggctgtc acttcatgat ttggacgcac
    10081 atctaaacaa aaacgagcgg ataatgattc tggcgtttgg acaagaagat tttcccgttc
    10141 actgatttct cccgaaagat aataaggcaa gccgcaattt gcaaaagaaa catacggtcc
    10201 tttttcaaaa acaacgattt ctgcatcttc cattaatcgg cgaagccgtg tagcagcaga
    10261 cattccacct gctacacctc cgacaataac gattttcatc ttatttccct cctactgttc
    10321 gatcaaacca ttgattcatg ccaccacgta cattcactac atcataacca gatttcttta
    10381 attctttagc tgcttgttta ctcctcatcc ctgattgaca aatcacatag acggtctttt
    10441 ctttgtctcc atcatatctg tttatacttt gtaatggaac atttttagct ccttttatat
    10501 gcccgccccg gtattctgca ggtgttctaa catcaagtaa cgctggattt tccaaaagct
    10561 tttcctttaa ttctgggact gttatcgatt ttattgattg aaatagcaaa ttcattttct
    10621 gcacctcatt tacattttta taaatacctc atggggtata ttaaacagga gctttattaa
    10681 tatgtcaacc agaatgactc ttcatttttt tcactacttt ttatatttgc ataaaatacc
    10741 gataaggggt attatctaat tataaaaata gaggagaatg tgttatggag attgataata
    10801 aaaatatcct gaaccgtttg aaacgtacag agggacaaat tcgtggtatc caaaaaatga
    10861 tcgaagacga aaaagaatgt atggatgtca tcactcaatt aagcgctgtt cgttctagta
    10921 ttgatcgcgt aatgggcatg atcgttgcag ataatctgaa aaattgcttt gagaaacctg
    10981 atagtaatcc agaagaacaa gcggctaaac tagaacaagc gatcaagatg attattaaaa
    11041 agtaaaggaa tgatttcaat gaaagtcgtt ttccatattg atgaattaga aaaatggtca
    11101 gaaacaggga aaaacgtaaa aaacctgata aaagcttctc cagaaacgac gattgtcgta
    11161 tctgtaaatg gcatcgcgat taccggttat ctagactctg ccaatgcaga attcttagat
    11221 ttgcaaggag tcgtttttca cgcttgcgcc aatgctatgc gtgctaatca tatttcagaa
    11281 agttctttac ctgaacaagt aatcgttgta ccagcaggtg tccttgattt agttgaactg
    11341 caatcccaag gttatgctta tatcaagcct tagtcagtag aggttgcgac agaagtgatc
    11401 agcttcaaga aatttcggct tatttttcga agaagctact tctggaaaac cgtgaatcaa
    11461 aggttgtgaa aacgctgtcc tgcatcaagt aataagaaca gccaaacaaa aatagcttct
    11521 catatttttc gtttggttgg gcttattacc gcagatgcaa gcttttgaac accgtttaag
    11581 gaagaggttg tgaaatcagc ggtttgacct aagtattaga gaaaaaaacg ggaaaatagc
    11641 tcctcatatt ttgccgtttt ttgagctaat accgaaggtc agctgattga acaccgttta
    11701 aggaagagat tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg
    11761 gatttctaca tttttgcata aatttggctt aataccgaga aactggcttt tgaataccgt
    11821 ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagaaac aaacggaaaa
    11881 atagctgctc atattttgcc gttttttgag ctaataccga aggtcagctg attgaacacc
    11941 gtttaccaag aggttgtgag cctaccattt aactccgaat cacaagaaat aatttcaaaa
    12001 acaacttctc ctgtttttgg ttcggttggc ttattatcga gaagtagcta ctgggagtct
    12061 atttatcaaa aaaaggaatg cgacataggt cacacccctt ttttattttc tttgaaacat
    12121 ctttcggtac tcgacagcat acaagacaaa agattgtaaa agaccgtaag tgatgacggc
    12181 aaaaatgact ctcacccaca gcgttggtaa ttctgggaaa agcagcaaaa ggatcatgcc
    12241 aacatagatg acagcagtcg ctactttgcc ataccacttc gctccactta atttgatatt
    12301 tttagatagc ccgattaatc cagctacaaa cataaagcct tcttttatca agaatagacc
    12361 aaacaacagc caaagccacg gtcgatacca tgccatagac aaaatcagaa aaagttgtgt
    12421 caatttatct gcaaacggat caagcacctt ccctaagtct gttacctgat tatatctccg
    12481 agcaatgacc ccgtctagat aatcagacaa acctgagaca acaatgaccg ctcctgctat
    12541 ataaaatgac tgtctcagca caaaataaag ataaatcggc agcaaaaaaa tacggaatat
    12601 cgataaaaga ttcggaatcg tttgtatttc tttacgccag tctgtgctta atttcatttt
    12661 atcgccctac ctcctcagca ctcttttctt tttattttag cttacacggg gaataaaacc
    12721 aatgatttca ctgtttttat ttttctttac agacactgat attatgagct aatttgagat
    12781 aatcacttgc tgttttcatc gtttactctt ctttcttcct gtcgtttgcg catttctttt
    12841 actagtactt tatgagcttt ttttgatcct cgctctaggt cacgctgccg tttacgtgtt
    12901 ttataatcga taaacagact gtctaaatcg taacctgtcg ggtacagatc ttctgctgaa
    12961 cgcaccagac gaacacgctg acgaggcacg tggattattt ttttgtctaa atatacatca
    13021 atcgtatctt cacctatatc ttcataaact aacgcttctt tttggtattc attgacaaat
    13081 atccgatcac cttttgcaaa gagctgacgt tcttttttat tctccttcct atttgtaact
    13141 gctgtcttag gaagaaattc ttttttctgt gtccgatagg ctttttccgc caagtaacgc
    13201 tctgcttgat ggatcaattt catcgacata tccattttat gagcaatcca caaagcttgg
    13261 ctttctcctg tttcttccaa cccgcaactg atatttagga cgaagtgctt cccgatcgaa
    13321 agccatagca gccggcacaa aatcttcatg atctccggcg aatttcttga tttctccata
    13381 atgggtcgtg gcaatgatca atgccccttg ctcatacata gattccatga ttgcgatcgc
    13441 tagtgcagcc ccttcatttg gctctgttcc actgccaatc tcatctaaaa gtaccaacgt
    13501 attccttttt atctttttca aaatagcagc gatgttttgc atatgaccag aaaatgtact
    13561 caacgcattt tctaaatttt ggtggtcacc gacatcgacg aaaatctcat caaagacagc
    13621 aagctctgtc ccttcttttg ccggaacttg cataccgaac atcgccatca aagtcaataa
    13681 accgactgtc ttcaacacga ctgttttgcc tccggcattt gctccggtga taatcaagcc
    13741 tcgatagtct ttaccgattt caacatccaa tggtaccgca tgctcaggta aaaatggatg
    13801 tctgccttgc ttgataatga tatgttccga tttattgatt ctaggtgtgc ttccattgat
    13861 ttctcggcta aattttgccc gagcaaagat gatatctaac accgtgatcg tttcgatcaa
    13921 taaatcgatc acttcttcgt tttctgcgat agcaccagtc aatgccgcca ggacttgata
    13981 ttcttcactg atttcttcag cttttaacaa ctgatagtgt tcattcaatt tagaaatcac
    14041 agttggttca ataaaaaccg tcgttctttt atttgattca tcgataatcg ttccatctat
    14101 tttattttta tagctggctt tgataggaat cgtatagtat tcgccttttt gaacaatcat
    14161 tgcttcttgg atcatttctt tgtttttcgg atgacgcaag aatttcagta attttgactg
    14221 gatttctttt tcgattagtt gtaattgttt gcgtacttta cgcaaattac gtgacgcgtc
    14281 gtcactgact ttattatttt ttattttctg gtcaatcaac tcttctacat ttatcaaatc
    14341 aggaagatgt ttgctataag caaacaacaa gggtgtctgg tattgattct tatcaaaaaa
    14401 ctttgtgatc atccgactgc ttctaagaaa atccgcatat tcgatcaaat cggttggctg
    14461 cagaatcaac ccttttttga cttgttctgt cagtgcatcg atcctcggca accccataaa
    14521 tggaacatgc tgactgcttt ctaagatcaa gcgtgcttct cttgtttctt cttgacgatc
    14581 caagacagtt tgtaggtttg tcgagaccgt catatcgctg attcgttttt tgctatagtt
    14641 tccaattgct cttgcttgga tttccttttt gatccgatca aattgtaatt gactaatcat
    14701 ttcgttgtcc atattctctc cttttcttga agagatacct gtcccaaaat aaataagggc
    14761 ctagagataa ataaaaggat agaacacagc ttaaaaaagt catgtcctat ccttattaga
    14821 atacaaagat attgttttcc tgacaggtac cgtttcataa gcacaccaaa taaactttgt
    14881 ttattggcta ttcgacttac tgattagata ccagctacac tcacaaaaca taccccattc
    14941 ttctaggtct tatttatttt ccacttaact atagcaagac acattttggt tgtcaaactt
    15001 tagtatgttt tatagattta caccattaat gaatagacac ctaccgcgat aattgctccg
    15061 atcattggac ctgcgattgg tacccatgaa tatgcccaat ctgaagttcc tttattagct
    15121 attggcaata ccgcatgtgc taatcgagga ccaaagtccc gagcagggtt gattgcatat
    15181 cctgttggcc ctcctaatga aagaccgatg gctaagatca atccacctac agcgaatacg
    15241 ttcgttccag gtgcaaattc gttttgtcca aaagctagca acccaagaac taatacaaat
    15301 gtaccaatta attctgtgat cacatttgct ggataattcc gtatagcagg acctgttgca
    15361 aacgttccta aaatcgcgct ttcatctttc gttgcattcc aatgtggcaa ataagaaagc
    15421 caaacaagaa tggcccctgc aaaagctcct aaaacttgcg caatgatgaa aggaacgaca
    15481 agattccaac taattgcccc tgtcatcgcc atagctagag agactgcagg attcaaatga
    15541 gctgggccca tgaatccaga aatatagaca gccattgtta cagcgagtcc ccaaccaaat
    15601 gcgatgacaa tccagccaga agcctgtgct ttacttttgt ttaaattcac agccgcacac
    15661 acaccatctc caagcaaaac taggatcagt gtcccaataa actcccccat gatttgagtc
    15721 atatcactgt tcatttattt ctcccccttt agttcccgca gatctgattc tgcaatcaat
    15781 gcttctaaac gtttagtctg ttgcgccttc tcctcttctg tccattcaaa atatccagca
    15841 attgcatcga tcacaggttg cttgatctca tcaagctgat ctcgttcaaa caacagatga
    15901 tttgtacgac gaatgagata atcgcctggg gccaaaacca tttcttcttc taaaccataa
    15961 cgtaaccgag ctgactcagc gagactcaaa ccaggataag gtgccatttc ttttgctaat
    16021 tcaaagatac gtcgggcatt agtcccgtaa aaatcagcga tataagtagc atcttcttcc
    16081 tctaaaccgg ctgctactcc ttcttttgct aattctgtca ctgtttcttc taatttagtt
    16141 ggatcgaagt ttccacctga aatctgatat tttttagagt cgatttcttt cgtctctatt
    16201 ccgtattctt cttttaataa ttggcgtatc aatcgcaaag ctccttctgc catcttacgg
    16261 taatcggtga ttttcccacc agataaagtc agcaaaccat ctggttctct ttctaaagaa
    16321 ctacctctgg aaatcgtaga aggtgctttt tcatcacggc tgttttccaa atggttcaac
    16381 acgtcttcta cttcagcacg agaaactttg ttttccttat attcacttac tgtatcgaca
    16441 actttattga agctcttgtc tgaaatcgat ccattatctc caccattgta atcagaacca
    16501 gaattaccaa tcaacagtgg acgaagtcct gcccagcttg cttcgatatc attcaatgtg
    16561 atatttgctt ctggatagcg atgattgatc acatccaata gataatctac atcttcttgt
    16621 gtgactttcg gatccgtaaa atctccttgg taatccgtat ctgtcgtacc aaagtaagtc
    16681 ttgttttctc ttggaatagc aaaaaccatc cgcccatctt gctttcctgt atcgaagtat
    16741 gtgggttgcg gtacaggcag ttttttcgca tctacaacta aatggatccc tttagttgga
    16801 cgcattttag gagagactgg acgcgtaaaa ttcaagtttc gtactttatc tacccaagga
    16861 ccactcgtat tgatcactaa ttttgctttg atttcgatca cttcatctgt cagcaggtca
    16921 cgagctttga cgccaacgat ttgatcgcca tcatataaaa agccaaccgc tttcatttta
    16981 cttactagat aagccccatc ttcggcagcc tttttgatat tatcaatcac taaacgggca
    17041 tcattgttgc ggaaatctag atagacaccc gcgcctttta gcccttcttt tttcaaaaac
    17101 ggttctcttt ccaatacttc ttctggtgtc agcgtataat tctcatattt ggttcctgtc
    17161 acatttgcca gtttgtcata aaggtccatt gctactttga ccgagaacat attgaaggtt
    17221 gttgctcctt cgccctcata gattggcaaa agcattggat ctggttttgg gatgtgtggg
    17281 gcaatacttt gtacgactgc acgttcacca actgtgtcag ctactacttc cacatcaaat
    17341 gtcttcagat aacgaatacc gccatgaaca agtttggtcg agcgagagga agtcccttct
    17401 gcaaaatcct gcatttcgat caatcctgtt ttgattcctg atgctgctga ctggactgcc
    17461 acaccggcac cagtgattcc gccaccgatg atcaacagat ccaattcttc ttgctgcatt
    17521 ttttgaatgc tatcttgtct tgtcttgttt gaaaacatat ggatttcctc cttattcaaa
    17581 tgcttgggta gcttttactg cttttttcca accgttgtaa agtttttctc ggcgctcttc
    17641 ctccatttga acttcaaata gcttgccagc ttcataaaat tcgcggatct cgtctgtatc
    17701 tttccaataa ccgacagcta atcctgctaa aaatgctgcc cctagcgccg ttgtttccaa
    17761 gttttctgct cgttggatcg gtacattcaa gatatctgtt tggaattgca tcagatattc
    17821 attgtttgct gcaccgccat ctactttcaa tacaggaatc ttgattccag tgtcatcttg
    17881 catcgtatcg atgatatctc tcacttgata agcaatcgac tgtaaagtag ctttaatgat
    17941 atcttctttt gtcgtaccac gtgtcaagcc aaacatagcc cctcgtgctg cctgatccca
    18001 ataaggagca cctagcccaa cgaatgcagg aacaacataa acctcatctt cgcttgtaga
    18061 gcgtttcgct gcgtcttctg aatcgctagc tttttgcaac atttgaagtc catctctcag
    18121 ccattgaatc gaagaaccag ccacaaaaat acttccttct aaagcatagt aaacctttcc
    18181 atttatgccg taaccaattg tcgtcaataa attatttttg gataattgcg gtttttcacc
    18241 ggtattcatg acaataaatg aacctgtacc ataagtattc ttgaccatgc ctggttcgaa
    18301 tgccatttgt ccgaataatg cggcttgctg gtctcctgcc atccctgaaa ttggtgcttc
    18361 gcttccataa aaatgataac cttgcgtata accataaact tctgagttag aagtgacttt
    18421 tggtaacatc actcgaggaa tatttagtaa atctaaaatc tcctgatccc aatctagctg
    18481 atggatattg aacaacatcg tccgactggc attcgagtaa tcagtaacat gtgcttgtcc
    18541 atcggtcagt ttccatacta accaagaatc gatcgttcca aacatcaatt cgcctttttc
    18601 agctcgttct tgcgcgcctt ctacatgatc aagaatccag cgtatcttcg ttgctgagaa
    18661 ataggcatcg atcactaacc ctgttttttc gcggaaaaat tcttgatagc cttcattttt
    18721 taagttatct gcaattccag ctgactgtct ggattgccaa acaactgcat gatagattgg
    18781 acgtcctgta tctttttccc atattactgt tgtttcacgc tggttcgtta tgccaatccc
    18841 agcaatctga tttggtttga tccctgattc gatgaacgct ccggcaataa ctgactgtac
    18901 agaattccag atttcatttg catcatgttc cacccaactt tcttgcggga aatattgcgt
    18961 gaactctttt tgagaactgc cgatgtgtct tcctttcttg tcaaagataa ttgctcgtga
    19021 gctagttgta ccttggtcaa tcgccatgat atacgttgat tctgtcattg tgattccctc
    19081 cattatatgc aaacgctttc tttaactact cttatcatac tactgtttta aaaaaagaaa
    19141 ctgtcaaaat tttattcttt ttttcttttt ttgacagttt tttattatga agctattttt
    19201 taatcaattc ttttcttttt tcagcgtctc tattcttctt ttcaatcgaa taatgtcgta
    19261 aggtgacgca aattctgaca gataatattc acactgtttt ttgtttctct ggcaaaatgt
    19321 gatcaccaaa tcatattctt taccttcttc ataacttcca atctcaatac cgccgattcc
    19381 cctcagttct ctgatcagat attgttgaaa agcaatacga taaatcggca gactttctaa
    19441 atcgattcca atcactactg gttttgcaat ataaaaatcg atcatcaaaa gaacattggc
    19501 atactggatc atcaggtaac taagctcact atcttcagct cttttcctcg gcaattgctg
    19561 caccgctgtt tcctgtaatt tcgccagtaa ctgtgttaag gaatgcccga gcattttctg
    19621 ctgctgttcc aaaagccgat cacgctcata gacttcgatc tttccaacaa agaaaaacca
    19681 ttcattgttg atctgggaaa tttggtagcc tactgccttt tcttctttga ttttcaaacg
    19741 acgaggacga taatgccata acatcgtttc ccgaatgtaa gtatctaaaa cagcggttgg
    19801 taactttttg ctccgtgtca aatcatactg ataaaatatt tcttcgtcta ctatcgaaaa
    19861 agaaacaaaa aagctgtaaa acatcattgt ttcgtataca ttcagttctg ctgctgttcg
    19921 actaagatgc atcacgatga ttggatcgat tgcttgataa agccggtccg actgatagag
    19981 taatttcttt tctttcaaag ttgcgtacgt acttttttca ttcaatagtc tttttttcgt
    20041 aatcccgagc cagcaagcaa tctgtgcttc tgctgatgcc gtaaacgttg tttctaatac
    20101 acggtccaat cctagaatga acggtctttt ttctggtgta ttttgcaaaa aaagcggtcg
    20161 ctgatcttcc gggatatatt ggaatagttc ataataaaaa tatcgtatct gtagctcttc
    20221 tccgtataat tgaccgtttt tgatttgtaa tccaaattcc tctaagagct ggttcaattc
    20281 tttgatcttt cgaaaaacag aagactcact gatattaaac gctgtcgcta atcgaacgat
    20341 ggatacttgc tgatgttcta ataaatagac gagcatctta aacttcaagc tttcctgcaa
    20401 taaaaacaat agaatttttt ccaaacttac atcttcgtcc aacacaagca gcgcctgata
    20461 ctcatttcgc tgtacttcta cttttttttc catcattcgg ccaatcaatt caatatcttc
    20521 caaatattga tcaaacgagg cttttgacag ttggacatgc tctctcaaac cattgataga
    20581 ggctgttccc ccttgcagaa caaggtttcg caaaatcagg atctgtaact gctcttttct
    20641 ttctaataat gcttcaatct tcataggcag tattcgccac ctttgaccac accatatctg
    20701 gcacacggta ttctggctgg aaaaatagct catgttcttc taactgttca aacgtccatc
    20761 cttcttctac tgcaattgtc agttggtcaa gaaggtggaa catctctttt ttgctttgga
    20821 gctgtgctcc aagaatcttt ttttcagaat caaatagaaa tttgagttta actttgcttt
    20881 gatttattgc tgtaagcttg tagtctacgt atcctgtttc aattttttgg ggataaaaaa
    20941 tgctctcttc ttctgtcaaa cctacgcttc ctaagaaata gccaaaccac tgattgccga
    21001 ctggacgata ggttccctga tcctttgtct gtgagccact aattgtcttg ctgacatttc
    21061 gtgctgtacg gacagcgtta tttactagag aaacatacat tttttcattt gttggacgaa
    21121 aagttacttg gatcgcatcg ccaatcgcat aaacgtcttt ttgagacgtt tgcaagtagt
    21181 catctaccca gatcgttcca tcatcattca atgttaattg ttcttcccac atctgattgt
    21241 cgggacgaga atgattagcc agcaaaacaa gatcatagtt ctcctttctt ttttccgtct
    21301 ctacaatagc ggtttcattt tcggtcaaag acacaacttg ttcttctaaa aaaagtgaaa
    21361 gcccttgatt tttcatttcc tttactaacg gttctgtcat ttcaggatct agataacgaa
    21421 aaagaattga ctttcggctt tcgtaaagat ggatttgttt ttttcttgat gccaaccctt
    21481 cagctatttc gattcctgct tgtcctgcac caataattgc aattttcttt gcattcatga
    21541 tcttttgctg aagagccgtt acgttttgta tctttttaac tgggtgaata agcgttgatt
    21601 ctgcagaaat atttcgaaac ttttgatttg aaccagtcgc tagaatcaaa cgatcaaaat
    21661 ccaatttttt tcctcctgct aaaacgactt ttttttcttt caatcctatt actgtctttt
    21721 ctgtgtaaac atggattcga tagcggtcag tcagttcttc tttcgtgatc caagaaagtt
    21781 gtttttcact ggtaaccttt ccttttaata tcaaattgaa cccgctggga atccatccta
    21841 acttcgattg cttttcaatc aaatatattt cacttgttgg catcaattgg cgaagataaa
    21901 tagccgcatg aatccctgca aacgacccgc cgacaattac aatgttcatc tgcattcctc
    21961 tttcttataa ggtgttctac tgctaacttc tcaatcagaa aacacagtat tcataactcg
    22021 ctttcaacct tatgatacat agcgatgcag cagaatcaac cctctccatc ataccgtgtt
    22081 ctaggtctgc ttctcaataa tgtactagtg gacctaattg aagagtatca tttctgaaga
    22141 gatgtttcaa aaaatgtact cttataaaag aaaaaaactc gccttttacg tacctctgtc
    22201 caaataggaa acagaaaaga acgaaaagac gagttttagc gtgtgtaatg taatagttag
    22261 aatagacaca tcatttattt ttaattcttt aatgcttcaa caactgcttc gcctaattga
    22321 tgagcagatt gaggattttg ccctgtaaga agccgcccat caatttgaac cacttctgaa
    22381 aaagctgctc cagactgata gtttgctcct ttttctttca aagcatcttc tgctaagaat
    22441 ggtacttcat tcgttgtacc atttgcttcc tcttcttcat tactgaaccc agtcactgta
    22501 cgtccagcta aaatagattt tccagactca tctgtaactg gcaacaatcc tacaacaccg
    22561 tgacaaacag ctgagaccag cccttcattt cgatagattt gtgaagcgac tttcccaaga
    22621 tctattgctt ctggaaaatc ccacattgtt ccgtggccac cagcataata aaccgctgca
    22681 taatcatttg catccacatc atcaggacgt aaggtatttc ccaaggcccg atttctgaaa
    22741 tcttcatctt cataataggc ccaatcgatt tcatccatat tcaaaacact ttgcggttct
    22801 aaaggtacat atccgccttt aggactgaca aaatctgcat cgatcccatt ttttactaat
    22861 acatcataaa aatgagtcag ttcacttaac cacaaacctg taggacgctc gatcttttcg
    22921 tacttttcta catttgttaa tacgatcaat actttcattt tcccatcctc tttctataaa
    22981 aattgcgtta ttgataacgt gctttcaaga aattatataa tgggcttggc aaataaagct
    23041 ctttatatgc ttcttcaaaa ggtttcgtta caaattcatc ctcacggttt tccaataatt
    23101 tctctgccca gtcaggatcg acgatcattt gctgtccaat tgctgcaagt tctgcatatt
    23161 tcaatacctg ctctacatct tcgcgattgc ggatcccacc gacaccaact aaagggatct
    23221 ttccttgaat cgtgttatgg accacttcaa gaatcgattt atcgttgtat ttatcagaac
    23281 gagctattcg atcatacata tttaatgaaa catgcagata atctagtttt gactcacgta
    23341 atcgttcaag aagccagatc gtgtcttcaa aacggatacc tggtgtttca tattcttctg
    23401 gtgagaaacg ataccctacg atgaatggtt ttttagcata ttgttcaacc gctgagaaaa
    23461 ccgttgttaa taattcttca ataaaacgat aacgattttc caagctaccg ccccattgat
    23521 cctctcgtct attcgaatgc ggagagaaaa attgttggat caaatacgta tttgctccat
    23581 gcaactcgat tccatcaaat cctgattcaa tcgctctacg tgtggctttg ccaaatgctt
    23641 ggattgtttc aacgatttct tcttcactca ttgctcgtgg tgtttccgca tcaggacgtt
    23701 ttgctgcaac tgcacttgca gatacaggct gttctccaga taaagttgct cgacttgtca
    23761 ttcgtccacc gtggaaaatc tgaataatcg cttttgcgcc ttctccttgg attgctttcg
    23821 ctagctcact taatcgagga atcatttcat catgagcgat gctgagttca cctggccagc
    23881 cttttccgat atcttggaca tttgcagcac cagtaataac agcaccaaga cctttagaac
    23941 gttgtttata ataagtgatc tcatcttcgg tgatcactcc attgaaaaag ctgagttgtg
    24001 tcgtcatagg cgacagcatc aatcggttct tcaattgaac tcctgaaggt aaagtaattg
    24061 attgatcaaa ttgtgacatt gtcattcctc ccataattcg ctctgattaa cctatcgaga
    24121 atcatctatc attaaaccac tcgattagtt gtacatgcaa ctaatttgct taaaaaattt
    24181 tatttttttt gtaacttatc tgttgcatca ttcattgtct gggctaattc tttacttgct
    24241 tcatttccca aaactgcttt gtatgactga tgaagttctt cccagctacc atcgacttcc
    24301 ttagcaaatt ggcgtccttg ttctgtaaga taaactaatg acaagcgacc ttcgctaact
    24361 gttttgacgt atcctttata ttctaatttt tcaacaaaac gagcaatcgt tgatggggcg
    24421 gaatagagca tttgtgcaat atctttttgt ggtattccat ctttttcttt taatatcaat
    24481 aaaataaaac cataagttgg tgccagacct gtccttctaa acgcttcatc agctaattta
    24541 ttcaacatgc gatctagctt tttcacgcta aagaaaagac attcatctaa cgctttttca
    24601 attggctttt ccatttcatc ccctccattg gcgtacatat catagtatga tttttatttt
    24661 ttgtcaaaaa acacggaata atgtccgcct cctctgtcta gatttgaaaa aaagaagtag
    24721 ccatcttcaa agaatttcgg cttgttttcg acaaaactcc ttctggaaca ccgtgaatca
    24781 gaggttgtga aaaagtcgtt tagttttgag tatgaagaaa aattttgtga aaatggcttt
    24841 ccacattttt gcataaattt ggcttaatac cgaaaaactg gcttttgaac accgtttata
    24901 tcagaggttg tgaaaaagcc gtcctgcatc aagtaataag aacagccaaa caaaaatagt
    24961 tcctcatatt ttgtcgtttt ttgagctaat gccgatggtc agctgattgt acaccgttta
    25021 ttgagaggtc gtgagcctgc cgttgaactc cgagtcacaa ggagcaattt caaaaaacag
    25081 cttctcatgt tttatgacta tggtgacttg tgatcgagga gttggcagga gaatactgtt
    25141 tattcgtaaa gaaggggctg tgacaagact tttgtcacag tcccttattt ccttttatta
    25201 taggatttcg ccatttgatt ggatgacttg tctgtaccaa tcaaatgatt ttttctttaa
    25261 ccgtttcttt gtgccattcc cttcgtcatc ttgatcaaca tagatatatc cataacgttt
    25321 tgacatttgt gaagtagaag cgctgacgat atcaatgcag ccccacgacg tataaccaaa
    25381 taaatctact ccatctttga tagcttcctt catctgctca atatgctgct tcaaatagtc
    25441 aatgcggtaa tcgtcttgaa cggttccatc ttcttctact ttgtctatag ctccgagtcc
    25501 gttttcagct atgaacagtg gtttttgata cctatcatat aattgattca aagcaattct
    25561 caaaccctta ggatcaatct gccagcccca ttcacttgat ggaagatacg gatttttaat
    25621 tcctccagtt attaagtttc cttggacccc ttcccaattt tctggatgag cactgactgc
    25681 actagacatg tagtagctaa aagaaacaaa atcaacaggg taggctgcta agatttcttc
    25741 atcacctact tctattttta agttgacacc tttttcttca aacattcgtt gcgtatacgc
    25801 tggataatat cctcttgctt gaacatcact aaagaacaaa gaagttcttt gctgctcaat
    25861 tgttttttga atatcatccg gatcacaaga atacggaaca agaagctgat agctgatcat
    25921 acaaccgact tgtgaacctt tgataatttc atgacaagct tttgtagcta aagcacttgc
    25981 tataaactga tggtgtgcac cttggtattt cgcttgttcc aaatggggat ggttttcttc
    26041 aattactcct acgctaacaa aagggtgatg ttttacacag ttgatctcat tgaaagtcat
    26101 ccaatatttt actttatttt tatagcgttt gaatactgtt tcagcgaaac gaacgtaaaa
    26161 ctgaataagc tttcgattag gccatccacc atattctgta accaaatata acggcatttc
    26221 ataatgggaa agagaaacga ctggctcaat cccatatttt agacattcgt caaacacttg
    26281 atcataaaaa aataatcccg cttcattggg tgtttcttca tcaccatgag gaaaaattct
    26341 tgtccatgcg atagacatcc gatagcattt aaaacccatt tcagcaaata aacggatgtc
    26401 ttctttaaag tgatgataga aatcatttcc gtgtctttta ggataataat acttgctgtt
    26461 gggatcctgc gccgctttta cttgctgatg cgtcatcata tgccattgat ctgtccattt
    26521 ttctttaggt aaatcgctgt cgaatgtata cacatcagac acagataatc ctttttcatc
    26581 tacatcccat gcaccttcac attgattggc cgctgtcgct ccgccccata aaaatccttc
    26641 tggaaatttt ttcatatcga tccccctaaa cttgctagtt ttcttgtttg attatttttc
    26701 ttatgactag taatgatatt tttgaatcta ctactatttg taacaataac cattgtggtc
    26761 ggatcatatc cctctttgat taattcttgc aaatctactt ccatcaataa atcgccttta
    26821 cgtacttttt ttccatcaga tactgcactt tgaaagtatt tgccatttaa attcactgta
    26881 tcaataccga tatggatcag tatctctgct ccttcttcac tgactacccc aattgcatgt
    26941 ttcgttggaa aaactgttga aacttccccg tttacagaac tgtagatttt tccgtccgtt
    27001 ggaatgatcg caaacccttc tcctaaagat ccactagcaa atgttggatc gtttacttca
    27061 gataaatcaa ttatttcacc tgctgcagga gtacttaaca ctatatcctt tgaggattct
    27121 tcttcgattt catccttgta gccgaaaaga aaagttagca tacaggaact gatcatcgct
    27181 aagaaataac tagcaactag ccaaacaaat ccttcaccaa tataaatcgg gaaagacaaa
    27241 atacttcttg tagcaactgc caaagcaccg gctcctgcgg caccagctac tccaccaaat
    27301 atagctccac atatacaagc aatgtaaaat ggtcgtttat atttaagagt cacaccataa
    27361 acagcaggtt cagtgattcc aaataatgct gtgataaatg cagataaaga taaacttttt
    27421 actttcttat ttttcgtttt caaaaatacc ccaagtactg ctcctgcttg cgcagctacg
    27481 gcagtcatac atgctggacc tagcgtatca cgaccgtaga aagaaagatt gttggtcatt
    27541 actggtacaa gtccccaatg taacccaaaa atcactaaca cttgccaaaa tccgccgata
    27601 acagcaccag ataaaacagg gctaaagtta taaacagcta aatatccagc tgcaatcagc
    27661 tgacttgcat aatctgcaat tggacctaca actaataaaa taattgggac catcacgatg
    27721 atacaaatga atggtgtcaa taaatttcga atactttcgt gcaagctttt gcgaatctta
    27781 ggctcaatat aagaaagaac ccatacagct aaaattgctg gaataaccgt acttgtatac
    27841 cttgctagaa tcacgggcat ccctagaaat cgcaaggtta tgctatcact atatgcactg
    27901 acaatcgtag gataaacgag agctgctgca ataaccatag cgatgaaacg atctgtattg
    27961 aacttttttg cagcagtata tgccaaaaat ataggcaaga aatagaaaaa tgcatcagct
    28021 gctgcattca aaatgatata agttcctgat tcagtagtta ataaattcaa actcgtacat
    28081 aaggcgagta ctcctttgat caaaccactt cctgccaaga cgcctaaagt cggggcaaaa
    28141 acagcggcga tcatgtctat aaaagagttt aaaatgcctt ttttctcagt tcctctcttt
    28201 ccactagatg catcatcttc tagtttcatt tgtttggata atacgtcata cacttcattt
    28261 actgcatttc ctactacgac ttgaaacatt cctccagctt cgactacagt gatcacacct
    28321 tctagttgct ctaccttctc cttatctgcc ttcttattat cttttagggt aaagcgtaac
    28381 cttgttgcac aatggtaaac attgctgaca ttttcttcgc ctccgacaaa tcggacaata
    28441 tctttcgcta attgtgaata gtccattttt acttccccct tgttaattaa tgccgtagca
    28501 atccttctta caagataagt atagttctta gaaaacggtt tctccattca attagtaccc
    28561 cttctaatag cgaacgaaac tgtacaatag tgtgtatggt ttacttagcc gagcaaatca
    28621 ctcactgctt gaaagaaaac aagtatatcg tttctcttat agtcaaagga gacaaaaaaa
    28681 acacgcttga tcttcctttg ctgatgtata agtggtatct caagctgata ctctgtgatt
    28741 tttgtttcta cttggctttt gataagacag cacaacaaag tctcggcatt taacggaagc
    28801 ataactaggt cagaactagg agagattagt tgctgaatgg aatctatctt tttatggatt
    28861 tttatttgat tttcttcttt gtagtaatga tcaagcagtt ttgttttctt tttttcttca
    28921 actatggtca gcttttcacg caaaatctga taaatctccc aagattcaaa ctcatctaga
    28981 acactaggta gataaatcaa atcatcccac tcaaaaataa gctcttgctc agtagtcaaa
    29041 attgcatcat attccgttat tttgtttgat tgatttttga aaagatacac tggttctatc
    29101 cggcattctt tgatccacat gttcatactt tgttgaatct gtttttttag tgtattcaaa
    29161 atactaattg gctggttact aacaatcagt atctcccctt gttttcgaaa aggattcaac
    29221 gcttcggcaa gatacaaaac aaaataagcg ctttcagcta aattgggacg taattgaaaa
    29281 tgtattggga agaaacgccg aattaaataa atttctaaag gataacggga gatgatcttt
    29341 tgtacaaaat gattcatggt attatgtccg gcatccatcc tcgttttcat ttgtttgata
    29401 tgggttagca aaaattctgt ttcatggaac aataacgaaa caggaagatc taaaaaacga
    29461 ataatcgttt gctcaaatgc tcttagattc ttctctattt ctttgttttt ttcatcatta
    29521 atcatcaaat aatttaactc taatagtcga ttttcaattg cttgtttttc ttgattggaa
    29581 aaagaatagg gtagttctga tgataacttt tttgtgaggg tctctaccat cggaataaat
    29641 aatgtatacc tgtttgtttt ttctaaaagt tcttctcttc gaagaatggt caaaacgaga
    29701 taccgagaaa atcgtatgaa gtcctctcct gaaacaatat aattatatga tataagaacc
    29761 tcttttaatg tcttttggac agtcggcatg atattggaaa aaattgtact gatttgttga
    29821 ggaaaccttg cgtgttggat caccgtttct gttccaacaa gagataagaa aattcttttt
    29881 gaattttctt cagcaatgat ttttagtcct tttgtcgacg aaacttccag ttctaattta
    29941 ggattgcgct cgatccaacg caaaatcgtt tttatttgta atgatacggc tgtttttgaa
    30001 agaaagaaaa tgtctgctat cttttgcata ctgacatacc ctttttgaaa caataagtac
    30061 gtcacaatag ttgaagctcg gaaatccatg ctggaataga ttttatgttt cgtcacctct
    30121 tgtatgattt gctgtttagt ttcagattca attgattcta aaaaataacc tgaacgttta
    30181 tttgactgga taatgatttt cttctcgtag atagcaagca tatttttgat ttcagtttgg
    30241 atcgttttct tgttggtacc taaagcttca gctaattctt cgcttgttat ccaatgattc
    30301 ttatttctta atactacaag aatttggagt tgtcgtttat ttaagtccat ttgcttacac
    30361 ctcctctttg ttataaacat acaggaaaaa cctctcaaat gacaatagtc acttgcagag
    30421 gtttaaaaat catttgaaga aagatctata ttcaaggttt ttaccattag actggataat
    30481 ttgtttataa tattcaaaac tatctttttt caatctccta aagcttccgc tcccatcatt
    30541 ttgtctatcc acataaataa agccatatcg cttcctcatt tcccctgttc ctgccgatac
    30601 gatatcgatt ggtccccacc ataagtaacc aatgatttgg caaccatctt ttattgcctc
    30661 agcaatttcc tgaagatgta tttttagata ctcacaacgt tttggatcgt ggattcgatt
    30721 caattcatct ggtgcttcat ctagtccaat gccattttca actatgaata atggtaattc
    30781 ataacggtct gtcaattcat tcatgacata acgaaaccct agaggatcaa ttggccaact
    30841 ccaaggttcg ggagattttt ccttcaaaaa gggattatcg aaaccatttg ctccgccagt
    30901 atctacgcgc atttctgctt cttttttata gacagcgcta cgataataac taaatgcaat
    30961 ataatctgcc gtgttagctt gcaagcactg ttcgtctcca tctaacatta ctggtgcaca
    31021 gtcttcttcc ttccatgtcc tgtaaatata agctggataa tgccctcggc acatgacatc
    31081 ggagaaaaac catgaattgc gtttaaattg cagtgaacca aatacattct ctggatcaca
    31141 gtcatatgca taagtcgcta atgcagaaaa gctacacata atacccatct tagcatttgg
    31201 atcgattttc tttaataatt gagtagcacg ggcgttcgct agaaacatat gatgacaggc
    31261 ttgataaatc actttttttg ttagtgtagc aatgggttca agtttatctc tagcagggaa
    31321 tgtaaccaat ccagcagctg cataaggcat acgaaaagca ttattgatct cattaaaggt
    31381 catccaatat ttcactttcc cttggtagcg ttcaaagacg gtctgcgcat aaaattcaaa
    31441 aaagtcgatt aattttcgat tttgccaccc cccatactct cctaccaatg ctaagggggt
    31501 ttcataatga ctaagagtaa ttactggctc gatatcatat cgatttaatg tattgattag
    31561 tctgtcataa aatacgagac cagcctcatt tggcttctgt tcgtctcctc ttggaaatat
    31621 tcgtgcccat gagatgcttg ttcgaaaagc ttttaaacct aactccttca gtaaacgaat
    31681 atcctcttca aatcgatgat aaaaatcaat cgcttcatga gaaagataat ggagtgattc
    31741 gtctaaagca atctcccaaa tctttttttc ttcattccac tgaatactag gatgctggtt
    31801 catgatcccg ataagcgtat ctgtcacatt aggtaatttg ccgtcttcca accatgcacc
    31861 ttcacattga ttagcagcta ctgctccgcc ccataaaaaa ttttctggaa atatttcctg
    31921 atccataact atctctcctc gctatcaaca atttcttact tgaagtatag ctcgattcat
    31981 caaaacaaga tattctaact atttcggcag aagagaagaa aaaaattgaa tgctactctt
    32041 catttttaat atttatatat aacaaataca taagacgatc cccgaaagaa aacactcgtt
    32101 aaccatctaa gcaaacgatt tattttactt ccaacacaaa tgcttcataa ggtcgtaaat
    32161 caactttgcc gtctggtaac tgtttcagag gataatttga cacaataacc cttaaagctt
    32221 cacgtggaat agtgaacgtc tgcttttcac tggacatatt acaaataacg agccattgct
    32281 ggtcttcata tatgcgagaa taggcaaaga catgctcagg cgtcttttcc actaattcat
    32341 agtctcccca gacgatgatg tcatgttttc tacgcaaatc gatcaatttc ttgtacatat
    32401 aaaaaacaga atcttgatct gctaacgctt cttctgcatt gatttcttta taatttggat
    32461 tgactcgaag ccatggaatt ccagtagtaa acccagcatg ttcacgggcg ttccattgca
    32521 taggcgtcct agcattgtct cttcctttcg ccttgattga ttccaagatt tcctcttttg
    32581 taaatccaga agaaatcctt tcgttataca tattgattgt ctcaatatct tttgcttccg
    32641 cgatatcatc gattgggcaa ttcgtcatgc ctaactcttc tccttgatag atataagggg
    32701 tgcctttcat catatggagc aagatagcaa acatcttggc actttctttt cgatacacat
    32761 cgtcatttcc ccaacgagaa acaattcgcg gaagatcgtg attattccaa aataaactat
    32821 tccatccttc atcacctaaa gatgtttgcc atttggataa tacttttttc agttcagaga
    32881 tactcaaggg tttcaaatcc catttgtctt tgccttcttg ctgatctaat cctatgtgtt
    32941 cgaattggaa gaccatggat aattcatttc ttttaggatt ggaataaagt ttagcgattt
    33001 cggtagttgc tccccatgtt tcgccaacag tcatcagatt tttgtcacca aaagttgctt
    33061 gattcatttc ctgaagatac tcatgcagtt taggtccatt acttgtgatt tctttatccg
    33121 gttctttgcc aatcatatcg atcacgtcca tacgaaagcc cccaatacct ttatcgatcc
    33181 agaaattcat catttgataa atctcttggc gaacctgttt atttttccaa ttcaaatcag
    33241 gttgacgctt gctatacaag tgcagaaaat attgccccgt tttttcatcc aactgccaag
    33301 cagaaccact gaatattgag cgcaatctat taggctcttt tccattgacc ggatcacgcc
    33361 aaatataata gtcccgataa ggattttctt tatttttacg ggcctcaatg aaccacggat
    33421 gttcatcaga agtatgattc accaccagat ccatgatgat acggatattt cttttctttg
    33481 cttcttcaat cagttcttcc atttcttcca tcgtaccgaa ttctgccatg attgcttgat
    33541 aattactgat atcataccca ttgtcatcat tcggagactc gtatactgga gaaagccaaa
    33601 ttgcatcaat acctaaatac gccagataat ccaacctgga aataatcccc cgcaaatctc
    33661 caataccatc ttgatttgaa tcttgaaaac ttcttggata gatttgataa acaactgaat
    33721 ggtgccacca tttttgttcc atgattttcc tcctataaat ggatgtttct attttttgct
    33781 taatcattta ttttagtctc tctcactaaa aattgtaacg ctttcaaata gctattgcac
    33841 cttgttatcg gtaacagaat aaaacaaaaa aacagctgag gaaattccct caactgtttt
    33901 ttgaaaggat tgatttatgc agggaagaat gctgatttca caacttcttt ataaacggtg
    33961 ttcactcagc tgtcccttgg tattagctca aaaaacggca aaatataaga aactattttt
    34021 tcgttttttt ctctaatact caggccagaa cgctgatttc acaacctctt tatttcacat
    34081 tcaatatcca catgaatccc acaaatacaa agaacagacc atacatgatt ggagatactt
    34141 cttttcctct tttagctgct aacatggtaa ttggatagaa gataaaacct aatgcaatcc
    34201 catctgaaat actataagtc aaaggcatgc cgatcaagat caagaatgaa gggatcgcaa
    34261 tctctaagtt tccccattcg atttgtcgca aagattgtgc catcaatact cctaccataa
    34321 tcaatgctgg tgcagttact tgtgaagtaa caactgatag taatggagaa aagaacaagc
    34381 ctaacaagaa gaaaatccct gtagtaatag ctgtgatacc tgaacgtcct ccaacggcga
    34441 taccagctga tgattctaca aatgcaccaa caggagaagt accaaataag gaacccgcaa
    34501 gcatagctgt tgaatcagaa gctaaagctt tccctacacg aggcatcttg ttgtctttca
    34561 tgaaacctgc ttggtttgct aatccaacta aagttcctgc tgtatcaaag aaagtcacaa
    34621 gcaagaatgt cagcactacg acccacattt gaagagaatt gatgtcccct acatgtttta
    34681 atgcaactaa aaatgttggt ttcaaacttg gtgctgcggc aacaatttca gaaggcattg
    34741 gaatcaaacc tgtgaccaga cctaaaatcg ttgtagctgc catcccgatg aagatgccac
    34801 ctggtacacg ccgaacaagc aagatagcag ttacgactaa tccaaaaatc gtcaaccaag
    34861 tagaaccaac gttgagtgat cctaatccta ctaatgtaga ttcattcgaa acgatgatcc
    34921 caccttcgct cagaccaagg aaagcgataa atagaccgat accgccagaa atcgcatatt
    34981 tcaaatctgc tgggatcgca tcaatgatca tttcccgcag cttgaagatt gtgatcaaaa
    35041 taaaaatcaa agaagcaacg aatacgccgg ctaatgctgt ttcccatgga atccccattc
    35101 ctaaacaaac agaataagca aaaaaagcat tgatcccaag agcaggtgcc gttccaattg
    35161 gataacgggc taataccccc attaaaacac agccgatcgc actggctaat gcagtcgcag
    35221 taaacactgc tccttcatcc attccagaag cacctaatac agttggattt acaaataaga
    35281 tataagccat tgagataaat gttgtaaatc ctgccagtac ctcacgtttt accgtggtgt
    35341 tcaatttttc tatttcgaag taggaaagta ttttttcctt catcttccat ccccctaaat
    35401 ccgaacatta taaataaagt ccgttaaaat ttcgatttat taataaaaca acgtgtttta
    35461 tcatatacta aaacaaaaca taagtaaaca aaaaattcgg attttaagca aaatccgaac
    35521 gttccatctg attaaatccc tttatctcaa agttcatgaa cattcacttt ggattacaag
    35581 aatttcttta ttgtgttaat aaagtttctt cattctagtc tcaaaaatca atagtgtgat
    35641 ttgattttac catttcgttt ctgttcttct ttgatgaatt cttttgtatc gacaggattc
    35701 agattattta gtccgccaaa acctgtatcg accatttttc cccagccttt tgtcttcttt
    35761 tttcctgatt tgagattctt tgctcgaagc ttctcactat gttttgctcg ccgatacttc
    35821 aaataacctt ctaatcttcc cattagatcc actgtttttc ctccttttta ttcaatcaga
    35881 cgactcagct tttcctataa caaaataatt gccttcaggg tcagaaaaat tgaaagtcaa
    35941 gatgccattg ttatctgtga tttctcctgg ttcttccatg ttctcgtaga tagtttcaaa
    36001 ttcatccgta aaaaatacta aagaaggcgg tggtcctaat acctctggtg aaaacttctg
    36061 cacaaatact tttgggaata cgcctaattc taattctttt gagatgctga gtacaatact
    36121 cttaaattct tctggcaatt cgattgtttc agaaatttct gcaccaattt tttctacaaa
    36181 gaatcggcaa atcatctcta cgtcattgac ataaagcatc acacgtgttt tttgtatcat
    36241 catttgaccc ttctttctat ttgattttct ttcctgtcta taaactgatt ccattatatc
    36301 acgaaagcgc aaacaccttg tgtttgatac tattcaagaa aaataaagca atagtttcta
    36361 ggattgcttt cctccacaaa ctttttttac aaaaaaaaaa cggcaatgaa tgccgctctt
    36421 cttatttcga ttcttttata attctgcttc tgattcatct ttggttagtg tgtgtctaac
    36481 actagttacg ccaaatgttt gatcgatttt ttccttcaac gcttcgattg cctgtgcgcc
    36541 acgtgccgct tgttcagcat tgatggattc aatgaccagc accgctgctt gtgtttcttc
    36601 cgtcagcatc gttctttggg cttcacgcca gttgagacag cgacagatcg ctccttgttc
    36661 atcatagtag atgatttctt ccggaagtgc cggagcatcg gaatctgcac ctaaaggcag
    36721 gaatgattcg ccaccttggg cttttcctaa atgcagattt cctgcgatct tttcgatatc
    36781 ttctccgccg caaggtacgc caaaagacaa ggaaatacta ttatagatat ctacaagcgg
    36841 attgattggg aaaaattccc gttcttgatt tgcacgtttc agtaaagctt caatagaaga
    36901 acgtgcacct tttttagtct tgaatgtggt aaatgcctga cgccactgag caatgacttc
    36961 gttttggctg aatgtttctt ctgtaaggta atttcttgct tcttttgctg cctcattcaa
    37021 taattgatga tacgtttctt cactttcttt tgttacgtgg ttatcgatac catttacgga
    37081 taagatttcg atggttgctt caggaaatac ttcccagaaa ttggtatcca ctattacttt
    37141 tttcatctgt tcacacctct tgattagaat aattgcttga tgaatagata gtctgtttgg
    37201 ggatcatctc ccatataaaa aacatgttcg ctgtatttga taaatccttt tttacgataa
    37261 aaagcgagcg caacatcgtt gtgttcccaa acaccgagcc aaatggctgt tttttgcttt
    37321 tcttttgctt tttcaatagc tgtatctagt aaaaatgtac cgataccttg atgtttaaat
    37381 ttttttcgta catagattcg ctcgatttct aaaaaatgat cagccatttc ctcagattga
    37441 ctcgttcctg tatttagttt caggtaaccc gcaggctctt gatcgatact cactaggaaa
    37501 aaatcggttt ctttatcttt tagctcttct gtaagttttt ctagtgcata agcttgtgtc
    37561 aagtaatcag ctaaatgctc cggtgaatta tcttttccaa atgtatctgt aaatgtttcg
    37621 atactaattt gttgtagtaa gtctacatct gaaggcgtca tttttcgaat ttcgtattta
    37681 ttcacggctt cttcctttca atagatcctt ttattgcctt ttttgacaaa attccaatct
    37741 tcgctaacat tcttgcatac tttatttaaa agatattcca attgttttgc ttcttcgtca
    37801 gaaagaccat ttaatgcgac tgcattggag tagttgtttt ctcgaatgat gaaaggatag
    37861 atttctgctc cttttttagt cggatagagt ttcttgattt ttttattttc tttatcttcc
    37921 aaacgttcga tcatcccatt ggattctaat ttcttgattg ctcgggcagt cgttgtacga
    37981 tctactttga tcatttctgc tagtttttct tggatgattc caggattttc gcaaatacgt
    38041 actaaataaa gatactgtcc tcttgttaaa tcgacttctt tgaattcgat attgctaata
    38101 gaatctagcg ctcgggcaat cattccgatg tctcgaagga tttcagccat ttcatcccac
    38161 ctttattttg tttgtaagac tagttcacct ctttttgttg caaatgcaac tattttcaat
    38221 aaaaaaatca agttcttttt taataactag taaagtatat tcttttcttc ttttacgaaa
    38281 aagctcaatc acaatagatc tggtttttgt tttctaaaat aagtaactgt ttcttcgttg
    38341 ttcgcttttc tgatagcttt ggcaactctt ctatactaaa aaatcccatg ttggaagttt
    38401 cattattctc aataaacttg gcctcttcac cgtggatcgc acaagcaaaa acaagtttat
    38461 aatactgaaa aagctgtgga atatcttttt gtttattcgt atcaaaaact gctcgcaact
    38521 gagtagtttc tactgttaat cctgtttctt catagacttc tttacgcaca ttttcttcag
    38581 gagacaatcc tatttcagca aatccaccag gaagtgacca ttctttcgtc cgtttatctt
    38641 cgattagtag gaccttgcca tcttttttga tataggcacg aacatctact tttggtgttg
    38701 gatgtccttc tccaatcgtt gtgagcgctt ttatttcttc gaaagtttct tttcctattt
    38761 cactgatcag ttccaatgaa atcgtccgga tctcctcaaa acgctcttta tcaaatacat
    38821 cttttccata atatagacca gcttgagaaa gtgcgagtag tcttttgtat tgagccaact
    38881 tcttgttcat tctcttccct tcttttttag caaatgtatg actatgtaat caagtataga
    38941 agactggttt aattacggca aataaatata atgaaatctg caataaataa aagaatgtta
    39001 aaaaactcga gaacaaaaga cattcgactt ctctggggct gtgaataaat ggcgttcaaa
    39061 agcttgcatc tgcggtaata agccccacca aacgaaaaat atgacgagct attcttgtct
    39121 ggctgttctt attaattgag gcaggacagc tttttcacaa cctccccact aaacggtgtt
    39181 ctcctaccaa ctcctcggtc acaagtcaca atattcatca aacatgagaa gctgtttttt
    39241 tgaaattgct ccttgtgact cggagctgaa cgacaggctc acgacctctc ggtaaacagc
    39301 gttcaaaagc caatttttcg atattaagcc atttctttgt tacttattgt cattgatttc
    39361 tttttctaat ttatccaata gtggagtgta atccacttga gtatagtctg ttacatcaaa
    39421 ttcatatagt gttcctaact ggaatttgtc atattttcgg tcggcgatga tctttttgaa
    39481 tgcttctttc gtaatatgat tggtcccttt cgttcgatct tccaatacgt caccatagtg
    39541 ataatgatcc atgatatagc tcaaatgacg atctgattca cgatcacgtt tgtaccgacg
    39601 ttgccataac acttcaaagt ctgctgttag gcgaatcgtg atcacctgat atccgtatct
    39661 atctgctaat tcttggagtc gtgctttttg cttatcacta aaaggatact cggacacaat
    39721 cactttcttt cctgcttcca tatacaaatc aagtgctttg taatagaaag gataaacttt
    39781 cgtcctttct tgttccgccc gttcttccaa attgttaaac ccgatggatt ctgcatagta
    39841 ttccttgatt tcatcgagcg tgatggcata catatctgga aatcgttccc gtagtttatt
    39901 cataagatat gtttttcctg taccaggact accagccaga agaatgaaat actttttcat
    39961 ctcatttatt tcctaagtta attggacttt ccaagttcat aaacagtcca atcttatgct
    40021 tgacaatttc ttttactgct tcatttgctg gaatcacatt atggcgaaga gacttgttga
    40081 tttctgtttc actaaaggtt tctttagcta ctttcgtcca gttgactaaa agctccgttc
    40141 caacattgaa tttgcggatc ccgttattga tcaattcagg ataatcttct tctttcacac
    40201 ctgttcctcc atggataact agggggacat caactactgc atcgatttct ttcagcaagg
    40261 gaatgtttac ttctgttttt gatttgaatt gtccatgatt cgtaccgata gcaatagcta
    40321 atgcatccac gcctgtagct tctacaaatt tcactgcgtc ttccggtctt gtatatacct
    40381 tgtcattttc agcgacatgg attccttctt ctgtaccgcc gattgttcca agttctcctt
    40441 ctacggaaac accgtgcgca tgggcatatt ctactactgc ttttgtcttc aggatatttt
    40501 ctttgaaagg cagatgggac ccatcataca tgacagaagt atatccgctg tcgattgctt
    40561 ctttgatatc atcaaagtct cgggcgtggt ctaagtgcaa gactgcatca accatttctt
    40621 cttctgcaat agctgtcatt acattgacta acacatgcat gccgatatat ttagcggtat
    40681 cgacacttgt ttgaataatg atcggcgaac ccatttcttt tgctgcgcct agcatagcag
    40741 gaagcatttc taggttatgc gtattaaaag ctccaactgt aaaattcaac tcttctgctg
    40801 tttttgttac ttctttcaat gttgtataca tcttttattg ccaccttatc tttttatttg
    40861 tttcctttga tcgttacttg ttttgcaatt tgtcgcatct catccatttt gcccatgtag
    40921 taatcgatcc cttgatcatc accagcacga gcagcatctg cacgcttctg gttatagagg
    40981 ctcatcagtt ttttataccc atctccgatc gtctgtttat tttccaaact cttttctaaa
    41041 tattggatgg cttgatcgtt cacatacaat tcagaaaatt taagtccaac ttgttcataa
    41101 agtttcgcta atttatgctt atcttgggta gtggaaatct cttgtttcaa ttgtgtaatc
    41161 tctgattgaa tcttttcggt cgcttctggc gatagggctt tttcttcttt tgccagaact
    41221 tttttcggtt ctttttcttt tttcttaaaa aatccaaaca tcattttccc tactttcaat
    41281 taaaatgctt tcaaaactgg gcttaagatc caggcatata agagtgctgc ggctactgta
    41341 tctacatcgg ttgctgtagc attgttgaat cccatcgaat taaagatcgt tactagcaaa
    41401 gcgggcaata atgtaataaa gaaaccatga gcaataccgc caatgatcgc tcctcggcgt
    41461 ccgccaactg cgttgccaaa tatccctgct gtccctccgg caaagaaatt ggttagcata
    41521 ccaggtaaaa tcatcgctaa gccgaacatg ggcaaagtaa acatggcaat aatcgtacca
    41581 atcgttgtcg taatgaaacc taaaatgaca gcatttgggc tataaggaaa gaaaactgga
    41641 caatctaagg cagggatcgc atcaggaact aatttcatag ctatccctcg aaatgccggc
    41701 acgatttcac ctaacagtag acgtacacca gctagcaata catacacacc cactacgaat
    41761 tggatggctt gtaaaaaggc aaacatgata tagttttgat ctcctgataa ttcagaagcg
    41821 aatggttcgc ctgcaaataa aacagtgatg atatatagcg ggaccatcac gaccatgaca
    41881 gacaaataag tatcttgcag aaattcgaaa tgtgtcggca acttgatatc ttcgatcgac
    41941 tttttatttt cgcctttctc accaaaaagc ttagcaacac cggcttcaaa taagtacccg
    42001 atcgtacaaa aatgacctaa agcaatatca tttgatccag tgattttacg aatgatcggt
    42061 tgcgctactg ccggcatagc aatggcgaaa caagctccga taaaaccacc gaccaagatc
    42121 aatacgatcc ctcgcagacc ggcaaaatag ccaaagactg tcgtcatcgt tgccatccat
    42181 aaaattgctt gaccagttaa aaaaatgtac ttccattttg tgaaacgagc caaaataata
    42241 ttgaatacaa aaatggctaa gaacgtcagt gcaatatctc tacctaaacc caaatcattc
    42301 attgcttgac cattgataga ttcaatagaa gggatgatcc cttgcatatg aaatccttca
    42361 gtaaagattt tcccgaaata agttaaactt ccaacgatga tgctcgaacc ggcactcaac
    42421 acttgaaatc ctaggagtgt ctttaacgtg ccagagatga cttgtcctgc tgatttcttc
    42481 tgcagtagta gacccaacat agcaatcaat gcaatggtga tcgatgcctg agtcaaaata
    42541 ttttcgatga taaaattgat aacgcccatg tttttaccct cttttctttt tgtatttaga
    42601 taactccctt atcttgcaga actggggtga ttttttcttc aatttcattt tttgaaacaa
    42661 tatttttcaa atagatcatc gccgttttag gatcaactgc gaacttttcg aactgcgaac
    42721 gaaaattttc tgctgtgatg atcacatctg gtttcatgga aactgcggaa gaaatatcac
    42781 aatggtccag tttggcttct actcctaatt tgttcaaaac atcctcagca gacatctgtg
    42841 ctgcaaaact acttcctaaa cctgcaccgc atacgaataa aatgttcaat ttgttcatct
    42901 ttgttctccc ccgtatcatt tattatttct caactactga aaaaagcagt tgtttgaaat
    42961 cttcgatatt tgtgcattca atcaatcgat ccaacttctc ttcgttgttg atcaattcaa
    43021 ttagttcttt catgatgttc agatgcgagt aggagtctac tgctgccaaa caaaaaataa
    43081 tctttactgg atccatttca ggattaccga aatcgattgg ttgctcaatc gtagctacgc
    43141 tgactcctaa tttattgacc ccatcttctg gtcgggcatg ggctagtgcc atgtgtttgc
    43201 caatcacgat atacggtccg taatcattca ctgcacgaat catcgcttcg acatagcgct
    43261 cttcgacaat gttttcttta accaatggtc tagcagctag ttcaatcgat tcctcccaag
    43321 tagtggcttt ttctttgatc atgatattgc tgtccgtcaa aatatctttt aacataggct
    43381 ggatctccct tttgttgatt tctaaattgt ttgtttcgaa taatttttct aacttgccat
    43441 agatgattcg atctactcgg ccaccacttt ctttcatgac atctattatt tgagtgaata
    43501 actccgtcga ttcatgactg ttaggctcta accgctgtag ttcttcattt cttttcaaaa
    43561 agtcttctat aaccaagata ttcgtctcag ttaaaatcgg atcgacaact aaaagcggct
    43621 tatttcgata attcaattga aaggtgctga aaaccagatt gacatccaat ttatctacta
    43681 attcgatttc ttttgaactt aaaactgcag taatctcgat ctgaggaaac ttttctttca
    43741 gattctctgc taacagattt ccagtagcca tcccatggtt acagacaacg actgatttat
    43801 aaacataatt caagtctcgc ttgattacac tggcgatcgt cgaaaagtgg atgacaagaa
    43861 aagctatctc gtcctccagt atcttgccac caattacttc ttcgatcgta ggaacaaaat
    43921 gagtgactgc gcggtagatt gggaaataat ttgttcggat gttttctttc aatggattca
    43981 tgacttggat atgattcttg attcttacaa tcagtgcagc catgtgctta tagagatttt
    44041 cgaataaagc ttcttccttt agatggaaag gtacgtgtgt ctcgttctct acaaattgga
    44101 tcaattggat cgttagtaat tgagcttgta cccactcgat tgaattggag atatctctag
    44161 cattgaacgt ctcaatagtg aaacgaagat aatttctttc tacttgcggg acattgtcca
    44221 attgaaattc ctcgatcatg tggtcaataa atgcagaaaa gctactgtct tttatttctg
    44281 tatttttcca attaatggca gagataaatt catgtttcct gattcgctgg atccagatca
    44341 atgtaaaaag caggatttgt tttttataaa tatcatcttc ttgtttcaac aacttattgg
    44401 aatagatctc ctgtattttt ttgatttcca ccaaaggaaa ataatggaga aagatttttt
    44461 gagccggtgt taattgtgca tcttgattca taaagaagtc ggtcattccc agattctgat
    44521 tgataaaatc atagatcatc gtacggatag atcgttctga acctttataa accagtcctt
    44581 gctttccata actgacgatc tctatcccat aactgaccag tgttgctcgt aaccgtctca
    44641 tatcttcatc taatgtactt ttagagattt gaaattcttc ttcttttttg tttagatgga
    44701 tcgggattcg gctgtaagca acggctaaaa ctagatcaaa aatacgttcg cgccgattca
    44761 aaaagccgtc tttcacatct tttatttcag tttctaatcg agcttgcttt tccttttcca
    44821 gcttcaacaa aaaacctttg ttgcgaattg tacggatctc cggaagcttt ttactgctca
    44881 accagatatt cgcttcaaga acttcctgac ggatcgtccg ctgactgaca ttgaactcac
    44941 ttgctagatg ttttgctttt actggatatt gggctgtcat gattctgtga agtatttcaa
    45001 ttgttcttgt tttcatagaa atgatctcct tctgatttca agtatatggt tccgcttaca
    45061 taataaaaag tagatatttc tgccacttga agtggaaaga aagtaagcaa agcaaacaaa
    45121 aaataagcca tatgcttttt catctcctca acgaaaaaga catacgccta ttattacaaa
    45181 aattttgccc atctatacaa aaaagaggtt gtgaaaaagc tgtcctgcat caagtaataa
    45241 gaacaactaa actaaaatag tgcttcctat ttttcgtttg gttgttctta ttatcgcaga
    45301 tgcaagcttt taaacaccat ttagtggaga ggttgtgaca gagatgttca gccttgagcg
    45361 ataagaagcg attttgaaaa atcgcttccc atattttaca aaatcgtgcc ttattgccga
    45421 taggctatct ctggcacacc gtttattcag aaaaaggagc tgcgacaagg cttttgtcac
    45481 aactccgttc ataaatattt cctgtcaatc cagcataatc ggctgaataa aatcggcttg
    45541 ccatcttttt tctttctcag aaaaatcaaa ataccatatc tgagaaaaat actgtcgttg
    45601 tgtcttactt cctgagatca atcgcccatc ttttcgatcg actgaataat cacagcatct
    45661 gaaatcaatt cggatggcaa aactattttc gtggatctgt cgataatttc ctacttcctg
    45721 aatagttatt tttttagtat gatttcttac accgtctgct ttgttttttt gcagaacttt
    45781 ctgatgttcg gcaaacagct tgtctgtata acagcttctg gctttttcag gagtttcttc
    45841 ttcccaagcg gattggatct tcatgaatat cttttggatt tccagaaact gtgctttctt
    45901 ttctttagcc gttcctgaca tgcgggacaa tatctccgct ttcagccttt tcttttgtct
    45961 tttattcttg acgatagaaa aagcagaaac ccctcctact gacaaaacag ctaatgcaag
    46021 aaatcccgtt tgctcataac tagaaggacc tgtacctgga ccataatacc cataagaatc
    46081 tctgccgtaa gaacgactgc caaaataact gcccccatat gaacgaccac caaatgaacc
    46141 tctgcccgaa cttcgaccgc tagatgtacc tccaccatga ccacccgcga cagcgaatcc
    46201 ttgggtcggc agagcaaaca aacataggcc cactaacaaa atgattgcta aataattgat
    46261 ttttttcatt gtcttcctcg ttatctttta ttacaaaaaa ctatttttat gatagccttg
    46321 ctaaaaggaa gagtcaataa ccagatgcat aaactgtttt tttagcaatt ttgtcttatt
    46381 tagtcattga gtaacatcgg acaaatgtat gtgtcggcag tccataattc ctctatcttc
    46441 agcatgaaca agcttgcaga caagagatct gcgcttcctc caggagagat ttggttttcc
    46501 tgacaaaagt gcaacagtgc tgtaaatgga cgatttggta aagcactttg actagcagca
    46561 tgagcaagtt tttgcatttc cactaacgtt ttctgatcac tgcgatgcaa tacgcatgtg
    46621 tcatctagcg aactcatcaa aactaacaac atatgcattt gtttctgtac atatgaatca
    46681 ttatctagct ccttagctgc ttgaattgca agcctgatat gcggataccc taatatcgct
    46741 tcttcatatg caccatttac gccatatttt tgcttcaccc tatgaccatg agtggttttt
    46801 ttatgacgat attttgtatc aggaaaagca gcaagcttgc tgacatcatc aagtattttc
    46861 gataaagaaa aaggctgttc catactgatt ttttgtgcaa tgacactgat caatagcccc
    46921 attgcccaaa tcgctccttt atgggtattg atgccatttg tagcaatcag cattgccttt
    46981 tccgcttttc gcccaatctc agcaattctt tctcttaact cctgatcaat agcatgatgc
    47041 catgctattt gagccatttc ttcaaaaaaa ggagttagcg tcttagcaga cttaagaaat
    47101 aaagcatagt ccatatcgga atgtgcaccc gcatccagtg catccactaa tccaggtttt
    47161 ggacttaatg ttacttctgc gatcaatgct tcctctacca acgcagcgag ttgctgagtc
    47221 actgcttttt ttcgttcgtc atttatcatg acactcactc cttcttccta ctattacttg
    47281 ctgaaacctt ttttgatagc tacccaaatg atatgaagta accagcttaa agcaaatgca
    47341 caacttgccg tcattagata agctacaaga atcatgactc ctgaaggtaa ctgcagccaa
    47401 ctatctttaa acaataataa cagtacttgg aaaacaaata cattggctaa atacgtacga
    47461 taagcataaa cagacaacca tttgaacaat ggcaattttg gcgaatcgtt tacaatcatt
    47521 ttggaagcgc ctatgaagac agcaaagatg atgactaaac tgtataaact ttggatcgta
    47581 ttcaagtaag gtgcattcgc aaagctcaag tctcctggat gtgcgagcaa tgaacggaca
    47641 gaaaagaacg cgataactaa ggcaacaggt aagaaaagat aacgtactct gtccaaatat
    47701 tgatagactt tttcgtgata aacaaatgcg gctaccccat aaatcatgaa actagcaaca
    47761 aaccgatcta ataagtacca gctgtcatga taaggcccag tcaatacttg tgtttgatag
    47821 aacagatacc atgcgacata taaaatcgtt gaaccaatca atactggcca tacatatttt
    47881 ttattagcaa atactttgta accgagccaa acaaaaaacg gcatgaacaa ttggatctgc
    47941 agcatcataa cggtatacca taaatgaggc gctccatcac ctgtgacata tttcagtaaa
    48001 aagcttgcag tatccgtata cggagtttgt tgttggactg ctggaaatag ccaaagataa
    48061 gccgtcgtcc atagaagata cggaacgact agttcaaaaa acttttcttt caaaaattcc
    48121 caataagaca aatgctgact tgtttttacc atattataaa caattgcaaa aataaacatt
    48181 ggtgctgtgt atttaacgat gacgtaaaag gtaccaagaa aagctgtatt tgttgcgctg
    48241 tggctgtttg ccaaagcaaa gctcaatatc gtttgcatca taacagccgt tacagctgat
    48301 actttctgga agtcacttac gttgattttg atttttttgt tttcaaacat ctctttctct
    48361 ctctttttct ttattaccaa agttctttgg ttaatttagg tccttcgact gttttcaata
    48421 gaattttttt ctctggctct ctcaaatact cttttagtga aaaaccgcct tgccgagtca
    48481 ctacttgggt atcgaattgc tcaaaaaaag caggatgcga ttgaattacc tgaattggca
    48541 attcaatcgg tgaatttgcg tacagcagca aatcaaaatc actggtttct tttactgccg
    48601 gaatcccagt cgataattca aatcctaagc tgccgccgat tccccattta catcctgata
    48661 atatgtttct agcagcatga aattgctgat aaacaggata atccatgatt ttctcttgtc
    48721 tatacgattc ttgttcgatg atgtcccacg gatgaatgac ttgtttgacg gcatgttttg
    48781 agatttctgt tgaccatctc tgattgcggg caggtccacg taaaccaatc ggtagtattt
    48841 ctgcgtgatc cgtcgacgca cgacgaactg ttccgaacat cttttcagtt agaacgaccc
    48901 attcaggcaa ggtgaaccct tctatttcat gtttatcaaa aaggacaata tcatgtgctt
    48961 gaatcatttt ttatgcatcc cattcttcgt ccattttggc acggacttta tttgtttcga
    49021 cacgtccgaa tgttttggct gtttcgtttg tgtatcgatt tgtcagcatc gtgtcatttg
    49081 tattgcggac atcttgaatg gcttcattga ttgcttcgat gactttgctg acattttgtt
    49141 ctgaagcagc ttggtcggtg atatcttcta ggaaatgata gatcgctcct agttttgtat
    49201 aattattgat atcgtaagcg atagctggaa ctttttcagc agctgcttcg atttcagcaa
    49261 ccgaacgttt tgtcacacgt gcagcacttt ctttagacat cgcttggacg gtaatttctt
    49321 tattgtttaa agcaatcaag cggcttgatt gtaatccatg tgctaaaaat gcacctgaaa
    49381 tagcatttcc tgcaatcaat ccaataactg gatgtccagc ttgacggagt tttgcataag
    49441 cagcagcact attagccaaa gccacatgga taccgatcaa ttcttcgtta tagccgtatg
    49501 cttggcttgg tacatcgatc acaacgatga ttggccgttt cacttttttg tctttatctt
    49561 cttcgtaaac gtgatccaaa atttgtccca tgcggaaacc ttcaactaaa ccaacttcac
    49621 cgtttcgtac acggtacatc gggtttttag gatcaggtac gattgatgtc acgatggctt
    49681 cttctatgaa tttacttgat ttaccataat acacagtact aatagaagaa gttggatttt
    49741 tcatgccagt tagtgccgca aaccaatcgt aaccaacact tgctgcagct ggttcatttc
    49801 cttctgctac ttctggtaag tcaattgatt ttgcttgatg gttagcaatt gcttcattgt
    49861 aatcgtcaat ggccattggt tttgaaagat ctaaagaatc aagtaatgat aaataaaatg
    49921 ctgagctttc actgcgatgc gtgtcttttc gttcgtccat tgctgcgatg acagcagctt
    49981 tgattgcttc tacactatca gtcactaatt catcaatgat ttttgattct acccgttgac
    50041 gagatcctaa tgtattccaa atcaagtctt tgtcactaga atcaaattct cgaacgcctg
    50101 cttcttgttc aataacttct ggtccattca aaccgactct cgcttttttt gttgcgatta
    50161 aataactcat taatgctgaa gtaatcgaca taccgccaaa tgatcctaca cgtcctggaa
    50221 tcaaaccgat gactggtaca tattgtttta gagcaatgat tacatttccg atttctgaaa
    50281 tagataacag tccgtagttt gcttcttgca aacgaacacc acctgtatct agtacaatga
    50341 ctggaaagat ctcatttcct tttttatttt cttctaacac atgttcaagt gcagcaacga
    50401 tttttgcacc ggaaacttca ccgataccgc caccttggaa ttttccttcc atagcgatta
    50461 ctactgcttg tttgccattg atcgtgccac ggctgacaac gatcccgtca tcactttcag
    50521 ggacgattcc ttgtgctggt aaacttggcg cgatgatttg atcgaatgga tcaatcaatt
    50581 cacgtccatt gtcaagtaga gcgttcactc gttctctggc gtttaattct acaaaactat
    50641 ttttcatctg aaagttcctc cattgcttgc gtcaatcgta ggtacacaac tcctggtgta
    50701 gcaccgaagt cattgatcac gatatctgct gaaattggat aacgatcaaa aaatctcgtt
    50761 aatacattgt tccatacttc gccgaagcca tcgcttcctg tacaaatttt tacagtagat
    50821 tctgtttttt ctgttggaaa catcaagatt tccaaatctc ctgaaccgac cactcctaca
    50881 tggattttct tattgatcgg ctgtttcgtt ggatatttat aagctaattg ttccatggat
    50941 ctctcccctt tttgtaaaac agagcataca cgttctgctt attcgtcttt cttcttccat
    51001 ctgggtaaat ggcgacaaaa ggtttttctc gccaatttta tgaccaagtt ctgaatttca
    51061 ttggtggttc atacaggcca tctgaccatt cgatcaaatc atcgatggtt tgtgcagcta
    51121 ataatgaacg tttcgcttca ctacgtttga tgcctagatc ttctggtaat ttcacgatgc
    51181 cggctgcacg caagctatct agtgattctt tcgtgctagt cattccaaga ggtgtaacac
    51241 cgccaattgc tgcaattgct gcttgtcgtt cttcttttgt ttttgctttg tacaaataag
    51301 caattccttc ttctgtcacg atatgtgtag tatcttcgct ataaatcatc actggtgcat
    51361 tggctaagcc tgcttgtttt tgaacagcta gtgcatctaa ttcttcgaca aagactggtt
    51421 ttttatttga accatatgtt tcaaccattt gaacaactaa tttttggcct ttccctaatg
    51481 gatcatcatt gtcgcgaagt gattgccatg ctggtgtaga atgacgacga ccgccaggat
    51541 tatgtcccat gttaggcgca ccgccaaaac cagataaacg tccttttgtt acggtagaag
    51601 agtttccttc gtaatctaat tgcaaggttg aaccgataaa catatcgatg gcatattgtc
    51661 ctgcagcttg tgataatgtt cggttactgc gcatcgtgcc gtctttaccg acaaaaaaga
    51721 catctgggcg agcagcaata tatttttcca taccaacttc gccaccaaaa ctatggatgc
    51781 tttcaaccca acctgattcg atggctggaa tcatcgttgg atgtgggttc aatacccagt
    51841 tcttcgcgat tttccctttt aaccctagtg attcaccata agttggcagt aacaattcga
    51901 tagctgctgt attgaatcca ataccgtgat tcaaagattg tacgccgtgt tctgcgtaga
    51961 ttcctttgat tgccatcatt gccattagaa tttgcaattc tgtgatgttt tgaggatctc
    52021 gtgtgaataa agcttctaat tgataaggtt tatctgcttt cacgacaacg tctacccagt
    52081 caccagggat atctacacgt ggtaaagaat cgacaacttc gttaacttga acgatcacga
    52141 taccatcttt gaaagctgca gcttcgatga ttgttggtgt ttcttccgta ttgaaacctg
    52201 tgtacaagtt gccgtcttta tctgctttat ctgcagctac taaaacaaca tttggaatca
    52261 aatcgatgaa taagcgtcca taaagttcca aataagtatg gatatcacct aatttcattg
    52321 tgccgtcttc aatcatttgg gcgacacgca agctttgtgc accagcataa gagaaatcga
    52381 tcttgcttgc gattcctttt tcaaaaatat tcaaatgttc tggtcgtgag atactagaca
    52441 tgatcaaatg cagatcattc actttttctg catctacttt ttcaagactt tctgaaagaa
    52501 aacttgcttg tttttgattg tcgccttcta atacaacttt gtcgccggga gcaatcagtt
    52561 tttccattac ttctacgatt ttttcagttt ctacatactt gccattgagc aagttgctga
    52621 ttttttccaa tcgctgcgct tttttttcgc gtttagaagc ccagttgcgg tttggttttt
    52681 ccataattag tcatctccat ttttgatata gaaacgtggc gtcatcaata ccatgttggt
    52741 ctagattgat cgtacggatc cctttatcta caccaaattt tgtatgaatc agctttgtca
    52801 aagtattgcc ggggggaaat tcaatcgtca gatccattcc taattctttt gccaagtcca
    52861 tcatttggtt ccactgcaca gggaaagcta ggttttccaa caaatcttta cgaatctctt
    52921 ctgcgtcctg agtggctctt ccatccgtat tttttatata caaacatcta gcatcagata
    52981 gatggacaga ctgcatatac ggcttgaatt tcttgaccgt atcattcatc aagagacagt
    53041 gagatggcac agggactttc agcagcttcg ctgtttgcgc ttggtgccgt ttggcttctg
    53101 ccaacgtaac ggataaacct tcgatactcc cagataacgt atgttgcatc ggacaatttt
    53161 catttgacag ataaactgga tggtcaggat caaatgtttt tgctacaatt tcctcagctt
    53221 cgcttctcgt cacacctact actacgccca ttgcataacc gcttggataa gcttctttca
    53281 ttaagactgc gcggtgatag actagttccg ctgcattctc aaatctcaaa gatcgacaag
    53341 caacagctgc acaaaaagca ccaatcgaat gtcctgctgc aatatcaggc tgaataccgt
    53401 ttttttccat ttcatctaaa taaaatactg cttttgtcag taatgctagc tggataaaaa
    53461 ccgtatcttg atagttttct tctttatcaa ctaaccgata ccccgtcaca ttttctaaac
    53521 gttccatgta catttcaggg atatccgcta acatccctaa cttctgactg ccttgtccag
    53581 gaaataagaa acctgtactc atgagcctcg cctcctcagc acttactttt tccactgcta
    53641 tcttagtcaa tttctgctat aataaaaaat gccaaaaaaa gaaaaaacca taacaaaaag
    53701 gtatggatgg gatggataat tatgaaattg cttcatctgc agtattttaa aaaagtattc
    53761 gaaacaaaaa atgttaccca agcagccaaa gaattattta tttctcaacc tgccttgagc
    53821 cgtgcgatca aacatttgga aaacgaatta ggtgtccctt tgttttacca tagcggcaga
    53881 aacattgaga cgaccgttta tgcagaagaa ttttatccat atgcagtcaa gacattagac
    53941 acattagaag aaggaatcaa attattgtct tcggtcaatg agaagatcgt tacttccgtc
    54001 atattgtatt tagaggtagc ctctgtttct attccgaact tggtccgaat ttttatggaa
    54061 aagcatcctg atatccaatt aacgatcatg caacatcatt taccagatga tattaccgat
    54121 cctgtactgt acatcacttc ggagatgaag cctggcatga ccaatattcc tatcatgaaa
    54181 gaacctgttt atgtcgccat tcctaagaaa catcctcttg ctaaaaaaga acatctgcaa
    54241 ttagaagata tccaacgcac ccccatcttg atgctgtcaa agagcaacgc cttccgtcat
    54301 acactggatg cagcacttga agcgaaaagt atcgaattga cgatcagttc gacgacagat
    54361 gatcctgcga cattacgttc tattgtcaag caaggattag ctgttagctt tttcccaaaa
    54421 gtttcttggt cttacgataa aaatgatcct ttcgtcttgc gggaaatcaa agatttgccc
    54481 ttgacacgaa caatttattt atcttctagc ttcacagaag atcatccttt gatcaaaatg
    54541 attgcaaaaa cgatgcggga attttattta ggaaaataaa aaaaaaagag ctgggacaaa
    54601 attcttgtcg cagctctttt ttcgaacaaa cggtgttcca gaagtaattt cttagaaaat
    54661 aagccgaaat ttcccaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
    54721 agctaaacat ttctgtcaca acctcttctc tattgtccta gacattcatt gcgttgattt
    54781 aaaacttcca tcaatcaaat ctgctagttc atctagcttt tctattttac gtagatcaat
    54841 agagatccaa tgttctttat tcatgtgata ggctggaaaa tacccctctt ttcctcgcaa
    54901 aattccgcca agttcaggat cgaccttcaa atcaagaata ttgatgatcc tatggtcact
    54961 tgcatcatca tagatttttt cttctggaac agacatcagg accccaaacc attttttgct
    55021 tttttgatgt ctgaatacgc aataatcagg aaatttttta aaaatatatt ctggagacaa
    55081 attgtatgtt tcattgatgt gatcgattag ttcttttttc gttagcatct gcttccatct
    55141 ctttcttatt gattcgcttt attcaaagat accacgtaag aatagaaaaa tgaatacaag
    55201 tagttgctaa tcaaatactt cgatattttt cttttttatc aactcttaaa tgttcaatcc
    55261 gcctgtgttg gtcttgctac catctactat taaaatgttt attattgttt gcccacctat
    55321 tttttgattt tagtggtatc atttttcaag ttcatgatga aattcttatc atcagtaaat
    55381 gctccagaaa aataaacaat gattgaaaaa tcagttgaaa cttgaccacc gtttattttc
    55441 tccgtattct tagaatagaa gggagtctga ttgatgtatt cactaatgaa aaaaatcatt
    55501 accgaaaaag atattcgacg tcatgtttct ttagtagaac aattgctgaa tcatacaaag
    55561 ataaccgtaa atgaattagc tgaaatcata gggacaaccg aacgaacgat tttttctgac
    55621 cttcaatcta ttcgctctca gctgcccgaa ggctgggaca tcatcagcga tcaagcagga
    55681 atcagtttgc aaaaccagca aaatttatta acaaatgacc tttgggagat ttttttcaaa
    55741 caatcagtca gtgtcgaact gctgaaaaat ctgcttttta caaaaaaagt tgctgtccct
    55801 gattttctag ccgaccatgg gctttcttat gggacattga aaagacatgt gactaaaatc
    55861 aatcagcgtt tagcaagtta cgacttgcag atcgatttga cgaaatatac agcttgtatt
    55921 cttggaaaag agcgtgcgat tcgtactttt tatcatcgat tgctgattcc tttcactcat
    55981 aacaactatt ttttcgagga ttattcgatc catgaatccc attattttca atttttaaga
    56041 aacctcagtc aaactgaact agcggttgaa acagaagaga ttttcggaac atgttggttc
    56101 tttatcaata cgatccgtat aaaagcgaat tgccgattag attcttctat ccataccaac
    56161 agcacactct cctccctgta tgactctgca ttgaaaaaat tgtatttaac ggaaggtatt
    56221 tatcttaaag acactgagct ttcttttgct tctttctgct ttctggaaag ttggaattac
    56281 aacaataact atggacaaga aaccgctcgc tgcctgcatc attctccatt tttagaggtc
    56341 ctcgaaacgt ttgtagagga actagcttca gagctgtctc ttgatcaact aaaaaaaaca
    56401 tctctgactg ataacttggc tctcctcata ttaaaatatc atgaatcgcc gatattgatt
    56461 gaagcattgg accgtcaata ccatcgtttt ttagaaacat atgatcagca atatgcacac
    56521 ttgtatcaac agaaagagaa tttactgaac gatctaaaaa aagaaataga aatcaatgaa
    56581 ccaaattact ttctccaact cttgtctcta ctgatccaac aaacgatttt ttctatcaaa
    56641 ccgaatttgt tcaatgtcta ttttattttc caaggagaac cttcatggaa ggcgttcttg
    56701 cagcaggaat taaaagatta cttaggaaaa cgtgtctgct tcttacctat cgaactaacc
    56761 gatctttcca ctatttcttt tgaaaaaaca gatatcttga tttccaattt ccctctagat
    56821 tctctagata tccctattgt atacatttct tctattccaa cgaaaaatga gctcaatcgt
    56881 ttgactgaac tcactttcaa aactttttta tagtaacggc tagcgactgt attctctagc
    56941 tgttttttct tttttgcgaa acagtttgtt catgatccct ttttctattt ctacaactaa
    57001 gaatagaaga atcacatttg ctccaatcaa taactgttgt gtcatcgtta aacttactgt
    57061 accgatcagc tgctggccga ctggtagaaa aataaccatc ccttgcaata aagcaaggat
    57121 acctaatgaa agaaaaagcg ctttgttttg caaaagacct tggttcaatg acggcttgga
    57181 caactctctg caattgatca tgtaaacagc ttgagctaag acgatatttt gcagaagaat
    57241 ggtttgctgt aagctttgcc cttcaaactg catagccaat aaataggcag gaaccatgat
    57301 cagtagggag acatagatga tccgaaacaa atgataacca gataggattc cttgctttgg
    57361 atctcttggt gggcgcttca tgatttctgg atctggcgac tcgaacccta gtgcataaga
    57421 taaagtgatt gtcgttacca tattgaccca taaaatctgt actggggaca aaggtagcgg
    57481 gcgattcagc ataagtgccc aaatcaagat caatccttga gctaatgcag ttggcaagaa
    57541 gaaattgatg gttttttgca aattatccaa aatccgccgg ccctctttta cggcttttgc
    57601 aatcgtatgg aaattatcat ctcctaaaac catatcagct gcctgtttgc ttacttcact
    57661 acctttgatt cccatagcaa ttcctacatc ggatcttttc aaagcaggtg catcatttac
    57721 gccgtctccg gtcattccga cgatttctcc atttttctgc aaagctttaa caattcgcag
    57781 tttatgttct ggtgtcgttc gagcaaagac atcgactatt ggcacttgct gaatcaactc
    57841 ttcatcagac ataagatcca aatcgatccc ttctaaaact ttggcagtat gttttaagcc
    57901 aatttgttcc gcaatcgctt ttgctgtgtc tttgtgatcc cctgtaatca ttttcactga
    57961 gatccctgct tgttggcatt cctttacagc tttgactgca ctttcttttg gcggatcgat
    58021 caatccggcg atccctgcaa aagttaattg ggttaaagtc tcatgcgtga gttcctgttt
    58081 cgaatctact tttttataag caaatcctaa aacacgctga ccttttctcg caaattctgc
    58141 agctgtctga ctccatgctt cttgttctgc agaagaaaga gttgatttag caaataatac
    58201 ttctggtgca cctttgacgt aaatcaccgc tcctttttcc tccgcatgca tcgttgccat
    58261 atatttgtat tcagaactga acggaatctt tgcttctatt tttttcaaag gtagattggc
    58321 tgtttctgtg tgtcgaatca gcgcaacttc tgtcggattg ccacttaaat tttctgtttt
    58381 ctgttcttct tttgttttta attcctgaca gtttttcata atggacaaca cgcaggcttc
    58441 ttcttttgca gctacatcca caactgtcat ttcatttttt gtcaatgttc ctgtcttatc
    58501 tgaacagatc actgtcatag aacctaatgt ttctaccgaa ggaagtcctt tgatgatcgc
    58561 cttttctttt gccatttcat gtactccaac ggatagaatc atggtcaaaa cagctggcaa
    58621 tccttcgggt accattgaca ccaccaaagc aatcgtagcc gaaagaagaa tatgccaatc
    58681 cataccatat cgaaatgtcg taaaaataac taagaatagg ctcaaacaaa gaatgccttg
    58741 aaaaatttgt ttgtttaatc ggttgatttt tttaatcaga ggcgtcgttt gttgttcgac
    58801 cgattgcaat gcttgattga ttttaccgat ttctgtcgtg tttcctgttt ctacaacgac
    58861 accgactgca gaaccagatt gtacaagcgt tcctgaaaaa cccatatttt tctggtcgcc
    58921 gatcgattct tcttctgtca aaacggcatg acttttttca gatgcttctg attctcccgt
    58981 caaaatcgat tcttccacta ataaatcatg tgcttcgatt aatcggatat ctgctggaac
    59041 gacatctccg gcacgtaaga caatgacatc tccttttacc agttctttcg cagggatttt
    59101 ttcttgcatc ccgtttgata gtactatcgc ttcttgtccc atcagctgct tcaaaccatt
    59161 caatgattct tccgcttttc tttcttgcca gtaactaacg agtccattga cgatcactac
    59221 gaataaaata atacttcctt caatatattc actagaagca aatttcaaaa aagaggcaat
    59281 gatcaacacg atcatcagca gatcagtaaa atgctttgct atttttttcc atcgttttgt
    59341 ctgctgcctt gcttttattt cattatatcc ttgatcagtc aggcgtttct gtcgttcttc
    59401 ttgcgacaag ccttctgttg atgtttgata gtttttcaat acatcttcta ccgtcaatct
    59461 gtaccagttc atcctatccc ctcctgttta attgatactg ttattatacg cagggaagtt
    59521 ttttcaggcg tatcgattat ttcagggggg tctgaaataa ttcgttttgc aaaatgtatc
    59581 tgggcctaac tgatatttct attgcttatt cttttatata caaaatttaa gaatacaaac
    59641 cagataacca ataaaaaagg aataaagcgt gtcgtgcttt cgaataacaa gctgaaagca
    59701 attgaagtaa aaaacaccaa caaagcaaga tctttatatc tttgtgtagt gttccgtttc
    59761 ttttctttaa taaattgaac atgtgcacac aagatcgaag accacacaaa tagaaaacaa
    59821 ctcgttgtca tgcctgccaa aagctgaaaa aacaatcgac tatcagctac aaaaaaatgt
    59881 agacaaagac cggcaaaaaa taacattcct gtaattaaaa taccgtgtaa aggtacgcct
    59941 ttcttagaaa gcgcacaaaa ccaatggggc aaactttttt cttttgctgt ttgatataaa
    60001 atcctgctag tactgtagac tgcactattt gctgaggaca aagaagcaac caaaatcatt
    60061 agattgacaa ttgctgctcc gccttggcaa tggatcactt gcagcatagt cactaaagga
    60121 ctttctttta aatctaaaca atgccatgga acaacaaata aaatcgacaa aatcgttcct
    60181 atatagaaaa agagaatacg ccaaggcaga cagttgattg cttttttcaa attcttttgc
    60241 ggatcacttg tctcgccaac ggttaagccg atcatttcaa ttccagcaaa actgaataaa
    60301 accataggaa atgagactac cattccagca aagccaaacg gtagtaattc atcgatctgt
    60361 ccaaaatttt ctttgattcc gatagactgg gtatgaaaat ctgagacact caatcctata
    60421 cccaataaga taaaaaggaa aatccccaag atcttgatga ttgagaaaaa agattccaat
    60481 tcaccaaacc acttgactgc aacaaggttg actgccatta agatcattag tgcgctacct
    60541 ccgcttatca aagctggtac atgtacaaac cagaaatgga tatacaatcc tattgctgtt
    60601 aattccgcaa gtccagctcc aagccagcaa agccaataag tccaattgac aaaaaatgcc
    60661 cactttttgc ctaaataata gtcaacgaaa tcactgatag agttaaatgt actatttgct
    60721 aaaaataaat cacccatggc ccgcatcaaa ccataaatag ccaaaccgca tatcaaataa
    60781 acgagaataa cagctggccc tgctgatgca attgcctttg ctgaacctaa aaataatcct
    60841 gttccaattg cgccacctaa tgcgattaac tggatatttc gattagttag agtccgtttc
    60901 attgccggtt tttccatcaa gttcaccttt ttctttttca agcagcatgg cgacttcctg
    60961 ttcccaagaa ggtttcttta ttttttcaat acagagtggt actacaaaca aaatgacact
    61021 gatggctgtg actgcaatta gattgatcca tgttccagct ttcatcgtca gtccgacaga
    61081 aaatccgatt gccgcaaata aaacaataac gacagtccaa actccaagat tgctcttttt
    61141 ctcttttttt ccaattctaa atggtcgatt caactttgca tgtgtataac gcaatctcaa
    61201 aactgcgatc cccatgatga catagacgat acagtagata acagtagttg aatttacgag
    61261 catcaaaaat gcttgattga cgccaggaat cagcaaataa aaaagtgcaa agattgagat
    61321 aatgacagac tgagtcaaaa taacggattt ggatacgtca aattgattcg tcttccaaaa
    61381 attgaatttt ggtggatacg caccttttct agcactttct gtcactgtct ttgctggtcc
    61441 tgaggcccaa gcagataatt ggactgctac accaatgaag acaagtaaac taaacagatt
    61501 cacaataaga tgtggcaaac caagaatttg gcaataaatc gaaatagatt gcgcgatatt
    61561 attcaattcc atttgtcctt ttggtacgac atttgctaca actaaagcat tcaaaatatt
    61621 gacgaaaaat ataaaaatta acgcggcaaa tactccgcga atatacgttt taactggatt
    61681 ttccaatcga gtgatataca cagaggacat ttcgatacca gtaaaaataa acatgatcgg
    61741 cgcaaaataa acaaatgagg atgcagtcgt agtatctggt attaatttgt cccatgaaaa
    61801 actgcctaat gttccggttg gtacgatccc aactttgatc cacgcagcaa accctaataa
    61861 gagcatcatc gtcaaaggca cgtacaatcc taaccaaaca ccgacttttc cgccgatttt
    61921 tgccatatca aatttcaaat tcaaaaaagt gatgatccaa taaacgacta aaatgacaac
    61981 taatgtaaat ttgctgttca aaccaagcgg cacattatcg ataatattac caaacaacgg
    62041 agcgagtgct gaagcgacca tcaccatccc aggaaacatt tggacccata acagccatga
    62101 gacaacgaac ccccattttt ttcctagagc attcgatacc caaagttctg gaccaccttt
    62161 ttggggaaac attccagcaa attcaccaga gatcaatgag attggaaaag cgtacaataa
    62221 tactgcaacc agcatgtaaa aaatcatcgt ccagctcgtt gctgctacat ctggaatatt
    62281 tcgtacactt gctacaaggg cgcaggtcat tccgataaag gtcatggtcg tgatttgctt
    62341 tgatgaacca gtatctttca tctttattcc ttctttcaat agcgacatat gtttttgttt
    62401 tcttttattt ttgttcaaga acagaaatga caaggtttca tcgattcagt acaaaaccca
    62461 gtatcaccga aacatccatt gaacgatctt agtgaactgg gtttgataca tgaaacgaac
    62521 gatccaactt atagaacgtt ttataaaaaa gaatatcttg gcgaggaata tatgaaaaac
    62581 agggggaaat acaattgttt tgatgaagca aataattgtc tgttctccat atgtctcttg
    62641 ttattctttc acacaaaaat cagttctatt ggatgatttc gtttagtttc ttttccattg
    62701 ctttggcgat tttttttgta taaaaattga aaattcgatc atcattcaaa taaggagtca
    62761 tgatagccgc acgtagcaga gtgattttct gttctttttt ccattcttct ttcgttagac
    62821 ccattctttc aacaaaacga atcggagaat caccgtaatc ttcttgtgta aatgtagtat
    62881 gagaagtaat aaaccgttca ccataaacat cgccatccat ataagaagac cgatcgaaca
    62941 ttttttcatt taattcattg atagcgttca aatctgtaca gccttgttct ttgaataccc
    63001 aattgaccat attaaaatca ggatgattca atggatagac ttcgattgtt tttcctttaa
    63061 cagtaaaagt cagatgatcg agaaattctc tgaatctttg agctgcctcg attgaagccc
    63121 caatcaattg accatatccg gtcacattca atggcaatac acgatgtgct gtccagactg
    63181 cggcggcggt tgctccagct tttgatcctt ccaaaatata agctcctaac atatctggag
    63241 cctttactga tttttcaaac acatatggcg cgaaataaga aatgatattt ctcatatttt
    63301 tatgtttgat tacgattcct ccagcagcat aagggacata gcccatctta tgaggatcta
    63361 tcgtgacaga atccgcttct gaaatagctc tgaacccttc atatacctct ttgtcaatcg
    63421 ttacgcagtg gtggaaaaca tgatgttctt caaagaattc agctaaggaa gcatacggca
    63481 caaattctcc tgcttcgttt agaaacagtg aacgcgcata gccgccatat gcggcatcaa
    63541 catgtaaata gaaatagatc ccttcatctt ttaacctttc tcttaattgg acgattttat
    63601 ctacactgtc tacttgacct tcttctgtcg ttcctacgac agcaaccaca cctagaattg
    63661 ggattttttg tccagctaat tcacgaattg ttttttccaa agcattaata tccattcgat
    63721 aatcctcttg aactgggata gcaaccatct gatctaagcc gactccgcaa atatctaacg
    63781 ccttcatcca agaatagtgt tttgtttgag ggaccagcca tttccctaat ctttggatat
    63841 tttttccgct acgggaagaa gctgctttga cctcatccat ttcttcgtcc gtaaagcttt
    63901 cggtcatttc caaaatttct tcaacagata aattcaaaag ttcccactca gacatttttt
    63961 tcactttttc aggcagcact tccttgacag ctaaaggaat cgatttgatg caacgggcgt
    64021 accataatcc ttcaagatta gcaatagaac catctgctgc aatgtgtccc catccgtctg
    64081 tcatattgaa taatgaagca aaatcctgtc ctacttctgc ttccatttgc gaagttgcca
    64141 tagaagattc caatgcaaca ttatttgggt tccacagcat cgcatagttg taagctaata
    64201 aagcaggcat caatgtttca gcattcattt gtccccagta acggcctgct gaatgccatg
    64261 ggatcgatcc tgcgcgtaat cgctgactga cttcatccaa gacctctatc atatggtcgc
    64321 gggtggctag ataatctgga gtgagcttat ctccttcgct aattgcaggc atatctgaag
    64381 gaatataatt ttctctccat ccaagatgtt catctaccat cttgttcaac aacattttat
    64441 aaactggtcc attttcagct ttgtcgccta taaagacggc cttgatatcc atatctttca
    64501 tttttcttcc ctccatattt tgttggtcaa tgtcttgcag atacatgtgt ttatctgtaa
    64561 cacctcttca ctatagcgcc aaaaatgaga attttttttt tataacatca aatccacgta
    64621 gatttttaca aacaaaaata aataaagtcg gatttttctg ataattcaac gcaaaaaagc
    64681 gaacaatttt tcaataaatc agtcttctaa aatagataac ctaaaaaaag cgaacaaaca
    64741 aataaaatga ctgtccttca ttcactaaac atatttttat ttttttatat tgttaaaaat
    64801 tcgcaattta ttttttaata gaattatctg ttttccaaat tttataacat aaaaaacctt
    64861 ttttaacggc atttatatgc tttttcagaa attaactgat gatttcaaaa agaaaacatg
    64921 tcataatatt tcccatattg tgcaaaaaaa tacaaggcgg aggctctact atgattgaag
    64981 aatatattga gaaaaatatt ttaagacagc tgtttttatg tgggcaattc tatgtaaata
    65041 aagaagtcaa tctagaaaag ctctccaatc tcctgcatgt ttgcaaaacc actttactca
    65101 atgatatcaa taacataaaa aaagaatttg aagaacagat cgcttataca catcgggaaa
    65161 aggaccgtta cactttatat ttttcagaac atatacctcg atgcaagatc atgcagcaat
    65221 tgtctcaaaa ttcgttgttt ttaaaaactt gtctgcttta tttggaagaa gatgaacctg
    65281 attatcttca attaactgaa tgtgaattca tctctgtcag caaagcttat tcattaaaaa
    65341 aacaagtatt agcttatttt aatgactgcg ggatcgaaat cgaccgctac tcccctcgat
    65401 tcactgaaat ggaaagacgt ctgctgcttc ttaatgtgtc gtatcgttta ggcggtttta
    65461 attcttggga gctacctgaa tcgttttttg aacgtgccga tcgtttcatt gaatccgtaa
    65521 cggaaaatag tggcagattt tatgataaag aaaataaaga aatcttatcg attggttttg
    65581 ctatcagttt cctacgccag caagtgtgtg ctgtgacaat agattcaaaa tttatcgaag
    65641 aaatcaaaaa acgtcctatt tacaattatg tcgaatcagc atgggaaaac actgatttcc
    65701 aaacctatta taaaaaagaa gaattcgcct ttattttgac actattcaat ctttgtaatt
    65761 atggtttcca ttcttatcag ttgattgcgg aagactttca acagctacac caagtgttta
    65821 ttgacaatac tcccgaaata aaagaactag ttgctacctt tgaatctcac ttcaatcaag
    65881 aattattcgg aaaccaaccg ttcgaacgtg cgctgattca tctgatgcgt tcggcttggg
    65941 ataactatca attattcatg ccagaaaaat tttatctttt aaatgaggaa cagacaaatt
    66001 tatataaaga agtccagaca attttttcca gctggtccag ccagttacct tatgatctac
    66061 ggttgaatcc taattgcatg cgggcttttg tgatcgaatt gagcggaatt ctccgtctga
    66121 caaaagaaca tctgactatc tatatcgtca caaattcgga tgttcattat ctgatttatc
    66181 gggaagcctt ggaagctgta actactttcg attttcaagt tgcaccaaca atttattcaa
    66241 gtatatctga tataaagaag tatgcgcagc agtcctcaaa ccgggtatta tgtgaacgta
    66301 cattatatac accagatgcg gtccaatatg aaaatattat tcctatttcg atcaatacga
    66361 tcgatcgagc tatcatttca gctgtgcaaa acaaataagg ggctgtgaca aaaatcatgt
    66421 cacagcctct tatttgttga agatgcccat ttctgtaaca atctcttgat acacgtcagg
    66481 ctcacaacct cacttatttt ggacatctac gggtccgatc tctttattta aaaaataaga
    66541 aatgatggtt cggataacta ccaacgccgc tagttggaaa atatcctgca aggtaggttt
    66601 gataatcgat tcgatgatcc cagctgaaac aagaatttcc aaacttagaa gtatatagcc
    66661 tcccaacatc tttttaatag cattgttctc gctgactcgg tcgctttgca cttttgtatg
    66721 gacaaataaa tatttcaaaa aatccttgat tgatagacaa acaccccaaa ccaataaaca
    66781 gatagcaaag atatcaagtc ccagtacaag tttttcgaaa tatggaagaa gaaactgcat
    66841 caactctgtc gtcatcctac ctctcctctt ctttgttttt ctttgtcttc tatttcctga
    66901 ttcaagaaat aagaaatgac tgttcgaatg ataataataa gtgcaagctt caaaatatct
    66961 gtccaagtcg gcttgataac tgactcgatg atatcagcaa cgactagtac ttccaagctt
    67021 aacaaaatat aacttgctag cagttttctt gtatctgcat tacgagtatt acgttctgca
    67081 tagtttttct tgacatgaga ccaatcaaaa agtttgaata gaacaagaac gatcccgaca
    67141 attaagatac cgatagaaca aatatttaaa atagcaatga tccattctag aaattcaatt
    67201 aaatttgagc gaaacatata cgctacctac tttcttttaa tttgttccta ttcttttatt
    67261 gtaaaagaaa gttaccttgt tcgtctattt aaaagttgtt ctaatgataa cggttcgctt
    67321 aaatttttct ttttcactct cccatttttc tccctccatc cataaatcgt ggaagtatcc
    67381 aaaacaacgt agcaagttaa aataaggctt agtccgtcat cagcttttca aagaagcact
    67441 gtctcggtgc tttttttgta cccaaatttc taaaaataga accatacacc tcctcaaatc
    67501 ttttcttctt acctacccta tttttattta caggaaaatc agacacttct tcttttttgt
    67561 caaaatttcc tttttcttct cgtcctatca tttggcattc taataaaaac gaactatcct
    67621 tggatataga aagagaaaac aaggaggcgt ttttcatgag taaaaaatta atcaaagtcg
    67681 gcatcggttt aggtttgctt gcccttggcg ctgcatatct aggaaaaaag acaggactat
    67741 tcgaagatga cagtcattta tatgatgaat tcgaatcaat ctagcatcct atttagttga
    67801 atcactacgg acatacttgg aagacattgg aggaatcaca atgagaaaaa gtaaagcaat
    67861 aatgattggt gccggtattg ccaatatggc agcggctgtt tatttgattc aagaaggcaa
    67921 atggaaaggg gatcagatca ccttttattc attggatgat cacggttcaa atgatggtgc
    67981 accgaccgac actgtagtgg atgaatattg gaataaaaac catccattag aaaaccaaaa
    68041 aggctatatt gctcgaggcg gtcgcatgct taattaccgt acctatgtag atttgatgga
    68101 tctgttaagt cgaatacctt ctgttactga gccagggatg actgctgaag aagatacgag
    68161 agattttgat gcaaaacacc gaacctttga caaagcacgt ttgatggaag gtggcaaagg
    68221 aatcattgat ggcggaaaac tgggattcaa taataaagac cgtattcttc tgactaaact
    68281 gattgctatg cctgattcag aagaagaaaa actagacaat atcactatcg aagaatattt
    68341 caaagatgat ccacactttt ttgaaacaaa cttctggttt atgtgggaaa caacatttgc
    68401 tttcagaaca cgtagttctg ctcaagaatt gcgtcgctat atgcatcaaa tgatttatga
    68461 attcactcaa atcgaacatc tagtgggcgt caatcgaaca cgttacaatc aatacgaaag
    68521 tattatgctt cctttgatcg agtacttgaa agaacaagga tgcaaaatca ttttgaaccg
    68581 ccgtgtcact gactgggaat tcaaagaaac accgatgcaa gatgaaatca ctgtgactgg
    68641 tttgaaaatt accaatacac tgactcaaga agaagaatac gttgtggtcg atgaagatac
    68701 agcagttatt ttcactaatg ggtccattac agattcagct actttaggag attacgaaac
    68761 accagctgta gaaaatatgg attatggtgc agcttctagt ctctggaaaa aagccagtga
    68821 acgtttctac aacttgggaa atcctgacaa attctttgct gatcgagatg caagcgaatg
    68881 ggtcagcttt accctgacga cgaaaaacca tttgttgttg aatgaaatca cccgtatcac
    68941 gactcaagaa ccaggaaatg ccttgaattc atttatttca accacaccga tcacgccgtt
    69001 aggccaaaaa gatgtcaata tgtctatcgt cgtgcatcat caaccgcatt ttacgtctca
    69061 gaaaccaaat gaaacagtta tttggggtta tttcctttat ccaagacgac gtggcgaatt
    69121 tgtggataaa cagtatatta aaatgaatgg aaaagaaatg ctagaagaac tgattggaca
    69181 actttcaaaa gtagatcctg gaccagtgaa tattcgtgaa aaagaaacag aaattttcga
    69241 cagcgtaata aataatatcc ctgtctatat gccttatgct tccgcgttgt tcaataatcg
    69301 tgccaaaagc gatcgaccaa aagtcattcc taaacattcg accaatctgg cctttacagg
    69361 agaatttgtc gagcagcctt atcagatgat ctttactgaa caaagtgctg tacgttctgg
    69421 agaaatcgct gctttccatt ttgcgggtat tcctatgtcc cgtcttgtca aaacaccgcg
    69481 ttacgacaaa gatattccta ctctagctcg tgccgcaaaa aaaatgtttg aataatcaag
    69541 aggttgtgaa aaagctgccc tgcatcaagt aataagaaca accaggctaa aacagcttct
    69601 tatgtttttg atttggttgg acttattacc gcagatgcaa gcttttgaac accgtttacc
    69661 aagaggttgt gaaaaagctg ccctgcatca agtaataaga acacccaagc taaaactgct
    69721 tcttatgttt ttgacttggt tggacttatt accgcagatg caagcttttg aacaccattt
    69781 accaagaggt tatgaaaaag ctgccctgca tcaagtaata agagcagcca agctaaaaca
    69841 gcttcttatg tttttgactt ggttagactt attaccgcag atgcaagctt ttgaacaccg
    69901 tttaccaaga ggttatgaaa aaggcgttta gtttcgagta tgaagaaaaa ttttgtgaaa
    69961 atggttcctc acgtttttgc ataaatttga cttaataccg agaaactgat cccttctgtc
    70021 ataacctctt tttatttatg tctgtttctt tttgaaaaca actatttttt caacgtttac
    70081 tctcttgcca atccaacatc atctaacgga tacaactatt tcaatgatta ccattacact
    70141 aaaaaatcgg aaacacacct ctccgaacac aaatacataa gactatagaa tgtttcattt
    70201 aagaaaaaaa gcgtttcatt atcaaaaagg taagatctcc tttaaaatga aattatctgt
    70261 agtactaata atgcagacaa ttttatgaat ctgaaaggag catctccaat gaaagcagtc
    70321 acttggcaag gaaaacagaa aatggaaatc agaaacgtag atgatccaaa aatattagaa
    70381 ccaacagatg caatcatccg tatcacagca acagccattt gcggctccga tctgcatctt
    70441 taccatcatg gtgaagcagt tttggaaaaa gggtatgttg taggacacga accaatggga
    70501 atcgttgaag aagtgggatc tcaagttcaa acattgaaaa aagggcaacg tgtggttatc
    70561 ccttttaata ttagttgtgg tcattgtcat ttctgcctga atcacatgga aagccaatgt
    70621 gatgaatcaa atccagatca gttatatggc gggcttttcg gatttggcaa gttgaacggt
    70681 aatcattggg gtggtcaagc ggaatatcta agagttcctt atgcagactc tacttcattt
    70741 gttgtaccag ataatgatct tcctgatgaa aaagttttat ttctatcaga tattttgccc
    70801 acagcttatt ggagcgttga aaacgcagga gtaaaaaaag gcgatacagt tgtgattcta
    70861 ggttctggtc cagtcggtct attcgctcaa aaattcgctg ttatggctgg agcagagcgc
    70921 gtaatcgcag tagatccagt acagcaccgt ctagataaag cggctaatta caatggggtt
    70981 gaaacttatt tcttagaaga cacggcacaa gctggaacag aattgtatga actggctaaa
    71041 ggtggcgcag atgtcattat cgattgtgta ggaatggacg gattagagcc tgtcaaagaa
    71101 aaagcgaaaa atttagtaag cttacaaagc ggcacaatct ctccattaca gatggcatcg
    71161 caagctgtca aaaaatttgg aacagtccaa gtaactggtg tttatatgac tccagcttct
    71221 tcttacccgc tgcaagaatt ttttatgcgg gatatcgctg tcaagcatgg acaggcacca
    71281 attatccatc taatgccaaa aatttacgca atgattgcag aaggactatt cgatcctaca
    71341 caaatcatta ctcattcgct gccactatca gaagcagcac aagcatatga gatctttgac
    71401 aaaaaagaag ataaaaatat aaaagttgtt ttgaaacctt gaattcagta aaaaatacag
    71461 gtgattttct ttatgcccaa aatcaaacga aatacccatg agatcgaaat aggaaaagaa
    71521 gaagatatcg aaatacgagg acgtcgcttc cgcttctatt tccaaaatcg ttacacattg
    71581 atctcactgg ctgtcgattt attaaccggg attttctata tttttggaag ccttgcttcc
    71641 ttaactaaaa tccccgatcg atatggcacc tatttttatt tggctggtgc tattttcttg
    71701 acgattcgtc ctattctcag aatcgtaagg aacattttta tttacgacga aaaaaaagca
    71761 atgaagagaa caagcaaaaa aaaagaggca tgagaatttt tcaaatctca tgcctctttt
    71821 ttcaccctat cgtatcactt tgatacagac gagcggtcgt cccactttct tccttgacca
    71881 ttgtcaaaaa tgtccactcg tatcgttcat aaaacgtggt atgatctgta attaagtaaa
    71941 gtttttcgta cccaagttga tgcatttctt ttctgatttc cgctaatatc cgcttggcta
    72001 tcccctgctt acgcttttcc ggttcaacaa acagggcaca aagatttggt gtcagatcag
    72061 ggcggttatg gaagtcgttt tcaatgacgc ccgctcctcc gacgatggtt tctttttcat
    72121 ctaagaccac ataccattga ggaatacttt ccttattagc gattccagta cgaatacttt
    72181 cctcatacac aacagcagga actccccatt ttgatgaaaa ccaattcgcg ctttgtttta
    72241 ctaattctgg gtgttctctt aatttgatcc agttatatgt aaccaatgtt taaacctccg
    72301 actaaaataa aacgtttaca aaaattatac aagtctttat gaaaattagc aatgacaaca
    72361 atagtgatgt aaaaaaaaaa cggaaaacaa tcacttgttc tccgtttttt gattaatcaa
    72421 gcatctaaag cttcttttct tctttcttgg atcgtagcta ccttgacgaa cggtagatag
    72481 atcaaaatag aaagaaccaa attgacagcg gctagtacac cacctgcaat actttttgtt
    72541 gccaatacac cgccaataat tggtggagtt acccatggag gcataacggt agctgctggc
    72601 actaaacctg tagaagtcgc aaagtaagca acactaacta agaccattgg tgtcaaaata
    72661 aatggaatga acatgatcgg gttcaacacg ataggtaacc caaacatcgt tggttcatta
    72721 atattgaaga cacctggcgc aatcgacaag tttgttacaa ccatatatgg tttgttttta
    72781 cgtcctacta aataaatagc taacagtaaa cctaaagttg cacctgttcc tcctaagttg
    72841 acaaagctgt caaagaaagg tttgttcacg ataaacggtg cgctatgccc agctgcgatt
    72901 gcattaacgt ttgcttcaat ggctggcgca ttgattgttt gcatcaaagg atcgaccata
    72961 ttcgctccgt gtaaaccaaa gaaccataag aatggtgtga taaatgcaag cagtaaggca
    73021 gatggataag agtttgcaag tcccataaat ggttcttgga ccactgtata gaaagaacct
    73081 acgatatcat caacaccgaa tgcagcaaaa attgcagcaa ctaaagcaaa cgcagagata
    73141 gtgatcattg ctggtagtaa tgaagcaaat gcttttgcaa ctgccggtgg cacaccatca
    73201 ggcattttga tgatcaattt ttcatttccg cttaaacgta caaagatttc tgttgaaata
    73261 atcccaacaa taatagcaat aaacaaaccg tttgagctca tacctaatgc tccgcctaaa
    73321 gcgaagaaag agcctaaaga aatcacacct gcggaaacac cgtcttttcg gtagccgtta
    73381 gctaaatgat aagcaagcaa gaaagcaatc aagacagaaa gaatggcaaa tgtaccgttc
    73441 caagcagcag ccccgaatcc tttccatgat tcaccaccaa aaattgagtt catcaattct
    73501 tggaacccgg gaatcggtaa gttattgatc attactgcta atgctcctaa gatcattaac
    73561 ggcatactca ccataaatga gtcccgaatc gcaactaaat gccgttgtgc accaattttt
    73621 gatgctacag gtataaaatg tttctccata aatgcaacaa atttatccat aaatcttccc
    73681 tcttttcttt actgtagatt acgcgttcaa tcgacgatac agatcaatga tctcttttgc
    73741 taaatctgta aaagctatag atgtcatcag atgatcttga ctgtggaccg tcaaaagcgt
    73801 gacttcaacg tgatttcctt gtgcttcttg tgtcagcatc tctgtttgag agtgatgtgc
    73861 ttggactaaa gattcctctg catctttgat tttttcatct gctaaagtga aatcaccttt
    73921 tttcgcagca gcaatcgctt ccattgcatc gctttttgca tttccgccaa acatgatcag
    73981 acccatgatg gcttctagat ttttttgatc ttccatttat tgtatcctcc gataattttt
    74041 attatttgtt tattagtttt tctgcttggt cgagtacttt ttcaccattc atcatgccat
    74101 agtcagccat attgattaca tctaaaggaa tgcctttagg tgctagcttt tcagcaaatt
    74161 gattttgcat aaagcgtact tgcggtccta aaagtaaaac gtctacattt ttagattcta
    74221 gttgattatc cgcatctgaa gcagatacag caaagatgtc tgcttccatt ccttttgctt
    74281 ctgctgcctt ttgcattttt gtgactagga gacttgtact cattccagct gaacatacaa
    74341 gcatgattgt tttcttttcc attttaaaca cgttcctttc tatacttaca cttgtatata
    74401 agcaagtagc gtgccaactt taaaagcgct ttaaaaagtt gatatcatca catttaaggt
    74461 ctataccaag ttgcatacac actaaaaaag aaagcgcaca ctaaacacac aaattaattt
    74521 ttattacctt ttttctttta acgtgcacaa aaaaagttgt gacacaaaac ttgtcacaac
    74581 ttttttcaaa taaacggtat tcaaaagctt gcatctgcgg taataagtcc aaccaagtta
    74641 aaaacataag atgttgtttt tactttgcta ttcttattac ttgatgcagg acagcttttt
    74701 cacaacctct caataaacgg tgttcaatca gctgaccctg ggtattagct caaaacgctg
    74761 gattcacaac ctcttttatt tcaaataacc agtaaataca atgaacatct acaaaaaact
    74821 tctatttatt tatagatttc gtcaggcaaa tccaattctc tcttatcaat caaagtctga
    74881 taccacgaag cagatttttt caatgttctg cttcgttcat cgttcaattc gattcgaact
    74941 aatccatatc gattcttaaa tgcattcatt ggtgacacac agtcagtgaa tgcccataac
    75001 atatagcctt cgcaatttgc gccttcttct gttgctttga tcaagtaatg caaatgctgt
    75061 ccgataaatt cgatacggta atcatcttgc acgattcctt tctcatccat atactgttct
    75121 tcatattctc ttcccatacc gttttctgtt atcagccaag ggatattatg ataattttct
    75181 tttagataca tggctatatc atacatgatt ttcggataga tttcccatcc cctggaatta
    75241 ttcattttct tcccaggtaa atcaaagact tcataatatc gttcaggatg gaaaggtgtc
    75301 tcttcattcc attgataacg aggggcgcga acgcgtttag gataatattg attgattcca
    75361 aggaaatcta ctgtatgatg ctgaatcgtt tctaaatcct ctgttgcagg atcgaaataa
    75421 atcgattgtt tttgacacaa ctccaggaac tcttctgtgt agtatccttt taccatcgga
    75481 tcaaaaaata ctcgattata aaacaaatca tacatataag cagctttttg gtcttctgga
    75541 gaattggatc gagcatagac catttcagga tttaaaatac agccaatcct tccaccataa
    75601 tttccgctgc ggtaaatctc tactgcttta gccgttgcta aaactttatg ataattccac
    75661 atcatccact tttttgtgtt ttgttcatgc ggccagcgaa cagcatccaa atagcaacgc
    75721 gtttggggaa cgattggttc gttgaatgta aaccagtttt ttaccctatc accgtaacga
    75781 tcaaaggcaa tttgagcata cttagcataa aaatcaacta cttttcttga agaccagcca
    75841 tcatattttt ccaaaagaaa agctgggact tcataatgtt ccaaacaaat catcggttct
    75901 acgtctgctt cgatcaaaga gtcgatcatt tcacttatat gctgagcata ttcttcatct
    75961 actatacagt tctcataatc agtaaaaaaa cgagcccaat tgatagaagt ccgataatgt
    76021 gtcagatgga tggatttcat cagatccaca tcctgctggt attgttccat aaaattagtt
    76081 gctacggctg ggccataccc attatgccaa acaaaatgtt catttttata ccagctatct
    76141 ataaacgaat cctgtccttc tttttttcct ttccaacctt ccgtttgcca agcagaagat
    76201 gcagcaccaa gaataaaatt ttttggaata gtaattttca tgatttcctc ctgtttttta
    76261 gatcccatca ttttccacac gatttgctac ttttacaaat ggcagataga tcaaaataga
    76321 aacaataata caaacaagtt gcgtaataac tgcaccgata tttcctgctg ttgccagata
    76381 agcattgacg atcggcggca ttggccaagg gaccattaca actgctttcg ccgcaaatcc
    76441 taaagcggtt gcaaaataac caatcgttcc agtgataaga ggcgttaaga taaacggaat
    76501 agctaaaatt ggattcagca tgatcggcat accaaaaata actggttcat tgatgttgaa
    76561 gatcccagga gcaagggata acttggtgat ttgtttcata tcttcccgtt ttccaactaa
    76621 caatactgca atcagtaaac cgatcgtgac tccagacccg cccatactca tatacatatc
    76681 ccaaaatggc atagtaataa tgttcggtac ttcttttcca gcttcaaaag cttccgtatt
    76741 tacagcaatt gccgctaaaa gcaacggttc ccgtatcggc ttcaccattt gatttccatg
    76801 gataccaatc acccaaaaga cttgcgcaat aaacatcaat agcaaaatac ccggtaaccc
    76861 ttgtacgaca ccttctaatg ggcgttgtac gacattgtaa atgatatcat aaaggtacat
    76921 tcctgtaagt tctttgatga taaatcccgc agccgcgata cccgatacag tcagaatcgt
    76981 cgggaataaa gcagaaaaac tagcagaaac attcgttggc acggtatcag gcattctcag
    77041 ctgtagtttc ttctgtttcc tcaaccagca ataaagttca atagaaagga tggagaccaa
    77101 cattcccaaa aataaccctt tcgtatctgt atattgttta gccaatacgt tttctactat
    77161 aacagtctga ttttcattca ctaattcata aacagttgga ttaacagata aataagacat
    77221 cactgcgatg ataccaggga atacaccatc cactttattc agcttggcta attcgatccc
    77281 tatcagaaaa acagcataga tggtcaagaa acttagtgtg acatagctga tggcagatgc
    77341 gataggcttt aattcttcta aaaaacgcaa gaaacttatc tgtgctaagc cattttccga
    77401 gtcaaagacc attgctgaaa acaatgtgcc aaaagcaccc gtaataatta ccggaatcaa
    77461 tgcagcaaat gcgtttttta tcaccatgat ataccttaaa ttattgattc tcgttgccac
    77521 gttccctaaa acattggcta atttatccat aaaactcatt ccagatcccc tcattcctgc
    77581 ttcttctcct tgacgtcatc tctttttgtc tattagtcag cgcttacatt tcgatgaaca
    77641 gaaactattt actcctcttt tttaccaaat ataaaacaaa aattcatctg atgtatttat
    77701 cataaaatac atcagatgaa ctgtcaatta gtttcttttt ctcctattat tttctgtaat
    77761 tctctccgat ttattgccat atggacagtc attgcatcaa acgcagcaag tgcattccgc
    77821 ctttcgatgg cctgaacgat ctctgtatga atatcgatcg tctcgatttt cagatgctgg
    77881 atatcataat ttttattaaa caaagcaatt gattcattaa tgattgggat aatatgcagc
    77941 aaggctacgt ttccgctagc ttctgcaatc atcgtatgaa aatcgatgtc taattgaaca
    78001 tgttcttgtg tgccttctcg aaaagaagtt tcaatctttt gcgttaattt tttcatttgg
    78061 acgatttgat tcttcgttgc atattccgct gccaaacctg ccatcttagg ctccaataaa
    78121 tatctcagtt caaataagtc tcgtatcatc cgatcctgat cttcaatcaa agaaaaaccg
    78181 agtgggtcat tggcaatccc tcgcttatca ctgacaaatg tccccgctcc ttgccgaact
    78241 tcaaggatat tcctggaagc tagagcccgc acagcttctc gcaccgtgct tcgccccacc
    78301 tctaaataat cggacaattc atattcattc ggcagtttat ctcctacttg caactgcatt
    78361 tcctttaaat atctaaggat cttgtcagta gttacttcta ctagggtttt attttcttcc
    78421 aaaccacata cctccttttc atctgatgta ttttttcgta attattataa cacgtttgaa
    78481 tcatctgatg attttttgta tacaaaattg attaatccgt tcatagacat acaaacgaag
    78541 aagatattta ccataaaaaa gactaggata aa
//
LOCUS       DACBYO010000002        74879 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.002, whole genome shotgun sequence.
ACCESSION   DACBYO010000002 DACBYO010000000
VERSION     DACBYO010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 74879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.002"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(1..144)
                     /locus_tag="IVD26_000074"
                     /pseudo
     CDS             complement(1..144)
                     /locus_tag="IVD26_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(186..1312)
                     /locus_tag="IVD26_000075"
     CDS             complement(join(186..1084,1084..1312))
                     /locus_tag="IVD26_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP6078089.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(1716..2498)
                     /locus_tag="IVD26_000076"
     CDS             complement(1716..2498)
                     /locus_tag="IVD26_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078090.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(2563..3399)
                     /locus_tag="IVD26_000077"
     CDS             complement(2563..3399)
                     /locus_tag="IVD26_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6078091.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(3417..4826)
                     /locus_tag="IVD26_000078"
     CDS             complement(3417..4826)
                     /locus_tag="IVD26_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP6078092.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(4840..6663)
                     /locus_tag="IVD26_000079"
     CDS             complement(4840..6663)
                     /locus_tag="IVD26_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6078093.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(6943..7170)
                     /locus_tag="IVD26_000080"
     CDS             complement(6943..7170)
                     /locus_tag="IVD26_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078094.1"
                     /translation="MIEIGYCLLIFTKKTSITIVAYIVGMLFIPSFTHQIHQFFPRAE
                     LLKLCDPLYAFLMLSRFWEFPAGYVGMVLLV"
     gene            complement(7506..7832)
                     /locus_tag="IVD26_000081"
     CDS             complement(7506..7832)
                     /locus_tag="IVD26_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078095.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(7878..8240)
                     /locus_tag="IVD26_000082"
     CDS             complement(7878..8240)
                     /locus_tag="IVD26_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HAP6078096.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(8277..8491)
                     /locus_tag="IVD26_000083"
                     /pseudo
     CDS             complement(8277..8491)
                     /locus_tag="IVD26_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            8619..8954
                     /locus_tag="IVD26_000084"
     CDS             8619..8954
                     /locus_tag="IVD26_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6078097.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9030..11027)
                     /locus_tag="IVD26_000085"
     CDS             complement(9030..11027)
                     /locus_tag="IVD26_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078098.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(11125..11400)
                     /locus_tag="IVD26_000086"
     CDS             complement(11125..11400)
                     /locus_tag="IVD26_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6078099.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            11632..12366
                     /locus_tag="IVD26_000087"
     CDS             11632..12366
                     /locus_tag="IVD26_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6078100.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12405..13547
                     /locus_tag="IVD26_000088"
     CDS             12405..13547
                     /locus_tag="IVD26_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6078101.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(13642..15033)
                     /gene="sufB"
                     /locus_tag="IVD26_000089"
     CDS             complement(13642..15033)
                     /gene="sufB"
                     /locus_tag="IVD26_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAP6078102.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(15038..15508)
                     /locus_tag="IVD26_000090"
     CDS             complement(15038..15508)
                     /locus_tag="IVD26_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAP6078103.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(15495..16730)
                     /locus_tag="IVD26_000091"
     CDS             complement(15495..16730)
                     /locus_tag="IVD26_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP6078104.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(16727..18013)
                     /gene="sufD"
                     /locus_tag="IVD26_000092"
     CDS             complement(16727..18013)
                     /gene="sufD"
                     /locus_tag="IVD26_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAP6078105.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(18026..18799)
                     /gene="sufC"
                     /locus_tag="IVD26_000093"
     CDS             complement(18026..18799)
                     /gene="sufC"
                     /locus_tag="IVD26_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAP6078106.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(18996..19844)
                     /locus_tag="IVD26_000094"
     CDS             complement(18996..19844)
                     /locus_tag="IVD26_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6078107.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(19868..20554)
                     /locus_tag="IVD26_000095"
     CDS             complement(19868..20554)
                     /locus_tag="IVD26_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6078108.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(20547..21581)
                     /locus_tag="IVD26_000096"
     CDS             complement(20547..21581)
                     /locus_tag="IVD26_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6078109.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            complement(21976..22314)
                     /locus_tag="IVD26_000097"
     CDS             complement(21976..22314)
                     /locus_tag="IVD26_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAP6078110.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(22316..22672)
                     /locus_tag="IVD26_000098"
     CDS             complement(22316..22672)
                     /locus_tag="IVD26_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAP6078111.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(22678..23865)
                     /locus_tag="IVD26_000099"
     CDS             complement(22678..23865)
                     /locus_tag="IVD26_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP6078112.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(24056..24901)
                     /locus_tag="IVD26_000100"
     CDS             complement(24056..24901)
                     /locus_tag="IVD26_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6078113.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            25135..26100
                     /locus_tag="IVD26_000101"
     CDS             25135..26100
                     /locus_tag="IVD26_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAP6078114.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            26477..27520
                     /locus_tag="IVD26_000102"
     CDS             26477..27520
                     /locus_tag="IVD26_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAP6078115.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(27582..28046)
                     /locus_tag="IVD26_000103"
     CDS             complement(27582..28046)
                     /locus_tag="IVD26_000103"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAP6078116.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            28292..29239
                     /locus_tag="IVD26_000104"
     CDS             28292..29239
                     /locus_tag="IVD26_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP6078117.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(29450..31522)
                     /locus_tag="IVD26_000105"
     CDS             complement(29450..31522)
                     /locus_tag="IVD26_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP6078118.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(31455..31832)
                     /locus_tag="IVD26_000106"
     CDS             complement(31455..31832)
                     /locus_tag="IVD26_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAP6078119.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(31961..32521)
                     /locus_tag="IVD26_000107"
     CDS             complement(31961..32521)
                     /locus_tag="IVD26_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6078120.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            32671..33963
                     /locus_tag="IVD26_000108"
     CDS             32671..33963
                     /locus_tag="IVD26_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP6078121.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(34023..35141)
                     /locus_tag="IVD26_000109"
     CDS             complement(34023..35141)
                     /locus_tag="IVD26_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAP6078122.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(35155..36576)
                     /gene="arcD"
                     /locus_tag="IVD26_000110"
     CDS             complement(35155..36576)
                     /gene="arcD"
                     /locus_tag="IVD26_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAP6078123.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(36822..37943)
                     /gene="mnmA"
                     /locus_tag="IVD26_000111"
     CDS             complement(36822..37943)
                     /gene="mnmA"
                     /locus_tag="IVD26_000111"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAP6078124.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            38347..38946
                     /locus_tag="IVD26_000112"
     CDS             38347..38946
                     /locus_tag="IVD26_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAP6078125.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(39084..40370)
                     /gene="efmA"
                     /locus_tag="IVD26_000113"
     CDS             complement(39084..40370)
                     /gene="efmA"
                     /locus_tag="IVD26_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAP6078126.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(40641..40985)
                     /locus_tag="IVD26_000114"
     CDS             complement(40641..40985)
                     /locus_tag="IVD26_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAP6078127.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(41122..42258)
                     /locus_tag="IVD26_000115"
     CDS             complement(41122..42258)
                     /locus_tag="IVD26_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP6078128.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(42447..43421)
                     /locus_tag="IVD26_000116"
     CDS             complement(42447..43421)
                     /locus_tag="IVD26_000116"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAP6078129.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(43501..44376)
                     /locus_tag="IVD26_000117"
     CDS             complement(43501..44376)
                     /locus_tag="IVD26_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAP6078130.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            44506..46413
                     /locus_tag="IVD26_000118"
     CDS             44506..46413
                     /locus_tag="IVD26_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAP6078131.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(46954..50232)
                     /locus_tag="IVD26_000119"
     CDS             complement(46954..50232)
                     /locus_tag="IVD26_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAP6078132.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(50503..51048)
                     /locus_tag="IVD26_000120"
     CDS             complement(50503..51048)
                     /locus_tag="IVD26_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP6078133.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(51060..51752)
                     /locus_tag="IVD26_000121"
     CDS             complement(51060..51752)
                     /locus_tag="IVD26_000121"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAP6078134.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(51771..52055)
                     /locus_tag="IVD26_000122"
     CDS             complement(51771..52055)
                     /locus_tag="IVD26_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078135.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(52068..52631)
                     /locus_tag="IVD26_000123"
     CDS             complement(52068..52631)
                     /locus_tag="IVD26_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAP6078136.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            52859..53521
                     /locus_tag="IVD26_000124"
     CDS             52859..53521
                     /locus_tag="IVD26_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAP6078137.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            53645..54841
                     /locus_tag="IVD26_000125"
     CDS             53645..54841
                     /locus_tag="IVD26_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAP6078138.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(54942..56318)
                     /locus_tag="IVD26_000126"
     CDS             complement(54942..56318)
                     /locus_tag="IVD26_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6078139.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(56355..57221)
                     /locus_tag="IVD26_000127"
     CDS             complement(56355..57221)
                     /locus_tag="IVD26_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAP6078140.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(57310..58335)
                     /locus_tag="IVD26_000128"
     CDS             complement(57310..58335)
                     /locus_tag="IVD26_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6078141.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(58353..59027)
                     /locus_tag="IVD26_000129"
     CDS             complement(58353..59027)
                     /locus_tag="IVD26_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6078142.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(59211..60104)
                     /locus_tag="IVD26_000130"
     CDS             complement(59211..60104)
                     /locus_tag="IVD26_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP6078143.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(60178..61875)
                     /locus_tag="IVD26_000131"
     CDS             complement(60178..61875)
                     /locus_tag="IVD26_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP6078144.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(61868..63181)
                     /locus_tag="IVD26_000132"
     CDS             complement(61868..63181)
                     /locus_tag="IVD26_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP6078145.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(63181..67218)
                     /locus_tag="IVD26_000133"
     CDS             complement(63181..67218)
                     /locus_tag="IVD26_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP6078146.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(67231..67689)
                     /locus_tag="IVD26_000134"
     CDS             complement(67231..67689)
                     /locus_tag="IVD26_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP6078147.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(67987..68505)
                     /locus_tag="IVD26_000135"
     CDS             complement(67987..68505)
                     /locus_tag="IVD26_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP6078148.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(68507..69124)
                     /locus_tag="IVD26_000136"
     CDS             complement(68507..69124)
                     /locus_tag="IVD26_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAP6078149.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(69121..69975)
                     /locus_tag="IVD26_000137"
     CDS             complement(69121..69975)
                     /locus_tag="IVD26_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6078150.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(69972..70883)
                     /locus_tag="IVD26_000138"
     CDS             complement(69972..70883)
                     /locus_tag="IVD26_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6078151.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(70924..72258)
                     /locus_tag="IVD26_000139"
     CDS             complement(70924..72258)
                     /locus_tag="IVD26_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6078152.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            72466..73296
                     /locus_tag="IVD26_000140"
     CDS             72466..73296
                     /locus_tag="IVD26_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAP6078153.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(73540..73789)
                     /locus_tag="IVD26_000141"
                     /pseudo
     CDS             complement(73540..73789)
                     /locus_tag="IVD26_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(73980..74174)
                     /locus_tag="IVD26_000142"
     CDS             complement(73980..74174)
                     /locus_tag="IVD26_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078154.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(74679..74864)
                     /locus_tag="IVD26_000143"
     CDS             complement(74679..74864)
                     /locus_tag="IVD26_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078155.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
BASE COUNT        21687 a        15865 c        13107 g        24220 t
ORIGIN      
        1 ctccagataa gtgcgatact cagacgcatc attcagtaac aaccgaacgg ttgtcgtccc
       61 ccaacgaatg atcctagagg ggacgacaca aagacaatgg gaacactctt ctggcttgta
      121 cagaagagtt cctttgtaaa tcatggattt gagtcaatat cttggacaca ttttagtaga
      181 gacggttaag ccattttttc ttttgctaat tcttcaaatt cctgtggggt tagatagtga
      241 atcgagctat ggattcgatt tcggttataa aatccttcaa tgtagctaaa tagcgctcga
      301 tttgcttctt caaaatctga gtagctagtc gtgtagactt cttctttttt caatgaggca
      361 tggaaagatt cgattccagc attatcataa ggtgttcctt ttctactata agaatgcctt
      421 attttgttgg ttttaagcca ttgttccact tctcttgctg tgtattggct gcccaagtca
      481 gtgtgtagaa tcattccttc tggaatgtga taatgtattt ttgctttatt caatgtttga
      541 atgacacaat ccacagtcat tcgttttgaa aatgtataac taataatttt tttcgtgtgt
      601 aaatccatga ttgaagataa gtaacaccaa ccatttttct tagtaggaat gtacgtaatg
      661 tcagctgccc atttctcaca gatcgtttca gtagaaaagt cctgatttaa gagattctct
      721 tttgaaatga tcggtttatt agacctttga ggtctatatt ttttaactac aatcgacctt
      781 aaatttaatt gtttcattag cttttggaca tgtttaagag atactgaaat cccttctttt
      841 aataaaactt gatggatctt tgtggcacca tagcgttgtt tattcgtaaa aaaaattgtt
      901 gaaatcttct ttttcaactt attatttctg atttctgtag ctgtcaacgg tttattctta
      961 taaaaataat agacacttct agggatttct aataaccgac ataacaaaga aacagtgtaa
     1021 tccttacacc atttttcaat aaattgaaca agcgaattta ggttttccga gagaatatgg
     1081 ctgcggcttt ttttaagatt tcaagttcct catttaaacg agcattttct tttctcagtt
     1141 cagctacttc ttttccagtc agtcctgtgg actgatcagg taaatataaa ttcttccatt
     1201 tgtaaatcgt tgcttcagat aagccatatt ctttcgctaa ccctcgaaca gaacgtccag
     1261 tttgattcag ttcaacaatc atttgtttaa aattttcttc atatcgggtc ataaaaattc
     1321 atcctctcgt agataagttt aatttattct tgtctctacg aaaagctgtc taagatttga
     1381 tactaacacc aagttatctt tagaaccatt tcagatacat atgaaacaat tacatatgat
     1441 tttttcataa aaaaacagta ctgtctagta gtataaaata tacaaatttc ttaaaaattt
     1501 tttcactaaa atcactacct gaaacagtct aaaacactta tatatcaacg tttaatgaaa
     1561 ctatctccgt ttcatttcag atacaaataa atatagtcgg gctccaaatc cgaaaaaaaa
     1621 tacccccagt agcttatcct aagctactgg agatgtataa gtacggtcat ataacaacgg
     1681 ggtagggtaa ataaatgaaa aagatggaag aatcattatt caataacttt tttaaatact
     1741 tcgttgtaat cagttacctg tccgttctta aataccacag aataatcttt tttcccattt
     1801 tcaagtaacc gaagtggaat gtctttacca acttgctctg tcactgcatt actgatacct
     1861 gttagattag ctaataaatc tgataaagat tgagcatctg tagaaatctc tgtatcagta
     1921 tttatcgtga ttcctttatc ttcatttaca agcttccaag taggtggtat agctgtgtat
     1981 gtttcgatga atgaatcaat tctttcatct atcgtcttcc cagtatctac ttctgtctca
     2041 ttactcttag atgaatcgat tctttcatcc atcgtctgct ccgtaactgc ttctgtctca
     2101 ttattctcac cggaaactct cttcacaccc aaacttatat attgtccatc tttagtgtgc
     2161 atagttaaaa ttcccacgct tttactaata aattcactat aaccagttct ttcaatagag
     2221 acttcaatgt atttcacact atcatactca aaagaaaaat agacatgtaa aagcattttg
     2281 ttgtttacat ctacataata atcctttgac tctacttgag accttcctat acggaataca
     2341 gctttactgt ctgatatctc tataccagca tccttattat taatctgcca atctccaagt
     2401 agctcttctg gcaagctagt agtttcttgt gaacacttta ccacttcact ggtagaggtc
     2461 gaaacattca cctccgcact gttagaagaa ttttccaagg aatcaggagc cttagcacaa
     2521 ccaacaagtc tttatatatt gtgcagccga tattttcttc attcagtaca cccttgaaat
     2581 atgcagtgtt agataaagca gttcgtcctg atttgctgag gcacccatct cttcttgaac
     2641 gtactccttg attttcaagg ccgcccgata ctctttcgga aaacgctgct tcactgaagc
     2701 cagcaaaaaa tcatccttct ccggcaactc ttccttctta atcattcggg caataaaaaa
     2761 ctgtaaatgc gtcacaaatc ttaagtaaag catcgaatct ttatcaacct ttttttcggg
     2821 aaacagatat cctagcatag ccaagatatc ctttagtgct cttaccgaga gcatggtttc
     2881 ttccatattt gcttgttcac tttgggcatt tacaatgtga aacgcaatgt ttccagcctc
     2941 ctcttctggc aactgaacat tcattttttt gttgatcaat tggatagcat agcagccgat
     3001 ctcaaattct tttgggtaat acttttgaat ttcaatcagc aggcgatttt gaaaaacaat
     3061 gcctttttga ctgcgttcaa tggcatgctt caagtgatca accaaggtaa aaaatagact
     3121 tttattcagc ttaaagtcaa acttggcgtt ggcataatcg ataattcgct tgacgcaaat
     3181 aattagatca tccggagcag cctcaaacag tttaatgtaa tcctttttta gagcatcaga
     3241 aagtgaatct aatttaaata ctttttggat tttgtcagcc ggaaccaaat cgcctttctt
     3301 tagttgaaat ccaatccctt tccccatcaa aattacttct ttgccttgct tatctaagca
     3361 aagaattaaa ctgttgttta acgttttaat tactctcatt agattcaccg ttctctctaa
     3421 gctaagccat ttcttgcgat tactttttga taccaaaaga agctttcttt ttttattcgt
     3481 tttaattctt taagattctc atcggttcgg tcaacatata taaaaccata acgcttattg
     3541 aagccttgat gggtactaac aacatcaatc gctgaccaag gtaaataacc aaaaacatct
     3601 acaccatctg ttaaagctgc ttgaatagcc agaatatgtt tggctagata atcaattcga
     3661 tcctggtcat taattcgtct atcttcctca actatgtcgg gtgccccata gccattttca
     3721 gtaattaaaa taggtaaatc atagcgatcg tacaatttcc tcaatgttaa tcgtagtcca
     3781 gtagggtcaa ctacccagcc atatggcgtt ttatctacat aaggattttc agctgcccgg
     3841 tagacacctt cttctcccaa catgatctgt tgatcccccg ctctagcgga aacatctgat
     3901 ccgtcatttt tgctggcagc gatggtggca gttgaataat aattaatcgc aataaaatcg
     3961 ggtttaccgg aggataaaat tgcctgatcc tctgcctcaa ttttaggata taatccacga
     4021 tcattcaaat agttttcaaa caaataattg tattttcccc gaactgctac atctaagaaa
     4081 gaccagcctc tcaatgtttc ccaattatgg gctgcaattg catcttctgg actggaggta
     4141 gcttgataca tagccgttaa attgattgct ggaccgattt ttcctttaag attcaactga
     4201 tgatacaagt gaattactct agcttgagct aataaaacat ggtgattaat ttgaaagagt
     4261 tctttttttg aaggcagctc tccacttggt ggcaaaccaa tcgctccagg atgaaggatc
     4321 atcgtgtttt gctcattaat tgtcagccaa tagttcacct tgtcaccata ctcagtaagc
     4381 aatacctgta catagtccac aaaataatcg atagttgctc gatttaacca accgccctgc
     4441 tcctctagaa aataaggtaa atcgaaatgg tacatggtga caatcggttc gattccctga
     4501 ttcaggcatt catcaattac ttgatgataa aaagaaattc ccttttgatt ggttttatta
     4561 ttttcaatat ccataattcg cgtccaagcg atggaaaagc gaaaagcttt taagcctaat
     4621 tctttaaaca gctgtatatc ttctttatag tgatggtaaa aatccgaggc aacttcaaaa
     4681 ttagctaccc cttctgtatg ctgatacttg tcaataatag acggttgttt cccatcctcc
     4741 tgataggcac cctctgcctg gtaggcacta atggaggcac cccataaaaa cttctctgga
     4801 aatgctgaaa gctgtttgta ttgcacaaaa atcctctcct taactaattt gcatcaatgg
     4861 ttcgtgttcc tttaagcttc cgcttgcttc actaattcct gcgtaatttt cactgttggt
     4921 cactaccaca atcactgtat catcgtagcc agcgtttcta atggcagcga aatcggcgtt
     4981 gattaataat tgtcctgctg acacctgatc tcctgctttt acaaatactt caaagggttc
     5041 cccttttaaa ttcacggtgt cgatccccac atggatcaat aattcaatac cttctttaga
     5101 acgtagacca atcgcatgtt tagattctaa aatagtaatg acttctccct caacaggtga
     5161 ataaatgctg ttttcttctg gatgaatggc tacgcccttt cccaatagtc ccttagaaaa
     5221 gacagcatcg ttcacttcag aaataggaca cacggttcct tttaccggat tttcaacaat
     5281 gactgcttcg gctattgccg tttgctctga ttcatcagaa gtatcgtcaa atccaattag
     5341 ataagcaatg ataaaggttg caacaaaggc gattacacac gtaataattg cgtgaacaat
     5401 attcattgga ttttctccaa taaaggctgg taaggctgct aagccagggg aaacaaaggc
     5461 atatctgact aaaccgctca agccagcata caaaccagca attgcaccac caatcatgga
     5521 agcaactaat ggttttttca gcttcaaggt tactccatag agtgaaggct cagtaattcc
     5581 cattaaagca gtgatcccag tggacacagc tagctgcttc aactctttgt ttttagtttt
     5641 cgcggctaca gcaaaggtag cacctgattg agcaatatta gaagccagca ttcctggccc
     5701 attgatcatt tcagaacccg tactgctcaa ttgcatagta gcgattggcg tcattgccca
     5761 agctgtaccc gtaaccacca aaaatggctg caaaccaccc atcaaaaatg gaattaacca
     5821 agctgctttg ccgttaatcc attcagcccc cattgctata agatcgttca gcaacgttcc
     5881 aaacggtcca atgacaacca acgctaaagg ccccataatt aaaaatacca gcatcggctt
     5941 agtaaagaat ttaataaacg aaggcgaaat tcgatccgca aagggctcta cataggacat
     6001 gatccaaaca gtaaagataa tcggtaaaac tgatcccgca taatctgcag ctaataccgg
     6061 aattcctaga aaagaaacgg catcgccagt agaaaaaagc tgtgaaatat ttggatgaag
     6121 caaaatgcca gcaacagtaa tcgccaaaat tgggttgaca tcaaacttta tggctgcccc
     6181 ataggctaat agtactggca taaaataaaa ggctgcatca gcaatagtat tcaaaatgat
     6241 gtaagtttga ctactgtctg atagtacacc agtcaaagtc aagacggcca aaatggcttt
     6301 taccatcccg gcacctgtta tagctggaat catcggtgta aaggtggtag aaatgacact
     6361 aatcaatctt gaaataatac tttcttgatt gtctgaagag gggccctttt taattgaagt
     6421 tcccacttcc ttttgaattt ccttgaaggc tgtttggact tcattgccaa tcaccacttg
     6481 gtattgtcca ccgctatcca ccacactaat tacaccaagt gttttttcta aggctttcgt
     6541 atcggctttc cttttatctt tgagttcaaa acgcagtctg gtggcacaat gggttaagct
     6601 gaccacattt tcttttcccc caacctgttg caatacattt cttcctactt ctctgtaatc
     6661 cattattctc tctccttaaa gcagtaaaaa agaccaagtc aaaccacgcc ccaatcaaca
     6721 ttgaagtgtt agtttgtctt ggtcttgcct gcataatcag taacatgcca ataacgttat
     6781 tttgctgtaa tccaataata gcacattatg atagcgcaat caacagggaa tttaattttt
     6841 tatcttttcg tttgaccgta tagggtaata taacagttag atcacatcaa ctagggtata
     6901 tctgcgtata cttactgcta aaataagtat atctaatatt aactatacca gtaaaaccat
     6961 tcctacataa ccagcgggaa attcccaaaa tcgtgaaagc atcaaaaatg catataacgg
     7021 atcacacaac ttcaacaatt ctgctcttgg gaaaaattga tgaatttggt gagtaaagga
     7081 tggaataaac agcattccaa caatataggc aacaatagtg atacttgttt ttttggtaaa
     7141 aatcagtaag caatagccaa tttcaatcat tccgagatat aaaggtatcg atagaatgat
     7201 ttgggctagt attcttaaaa attaactagc aaatgtttaa actgatttat ttctaatcta
     7261 catgtagtaa gtatttcaat tccaccaatt atcaataaaa ataccaaaca tatccataat
     7321 aattttttct ttttcatttc ttttatattg ttataacagt gaataacata aaaattcccg
     7381 acaatcattg taatattttt ttgtcacctg tattagtatt taatttatag gaaactataa
     7441 aaactcccta gtgaatttac acctttggga gttcctgttt ggacggtatg cataatacat
     7501 ttaaatcaat ttaacattaa cacctcagca tatggtatct ccacatatat acggtctttc
     7561 tttggatagt actcaatatt tatgttgata gcacttccat tgtctaatat agctttagcc
     7621 cggtatgtgt tatctccatt ttcatgagta atcgtcacat catcacatga tcgatttaag
     7681 ttgtactgtt cttgtaaaat ctgtgttacc aatggtttcg atgacttctc taatccagat
     7741 gtacctgtca tttttgaaaa aatgatacct ataatagcca agacaacgat aactataatg
     7801 ataaacttct tgttcatatt tactttattc aactttttat ctcctatctc caaaataatt
     7861 tgctcttatc cctcttatca gtacattgac atccctaaaa gtacaccaaa gattgctcca
     7921 gctacccctg ctatcatcaa aatcgtaccc atttgttcat ctttatctcg atataagtag
     7981 cccataataa cagcaacagc accaaataca acaggaataa atgctaacgc tactaccata
     8041 gaaatccaac caataatcaa atacagcttc cctgtctctt gtccatgtac gatttgttcc
     8101 ttcatttcat taattgtctg ctcagtactt ttctttactg cgtctgctcc agttgtctca
     8161 tctgtttctt gtagtgctcc gcaaaactgg caatacttac tttcatctgt tatttctttg
     8221 ccacattttc tacaatacat gtcttctcct cctaaaaaca ttcaattgtt tattagttaa
     8281 ctgtttactt tattaaatac atcagaaaac agctcattca ttggtacact taatatctca
     8341 gaaagcatct tcatttgata gggtttagga atcgttctcc ctgtttgcca cgaacttaca
     8401 cattgctgtg taacattcat ttttttgcta actccgtttg agaaagtcct ttttcttttc
     8461 tgtatcggct gagattactt acttttttca tgattctccc ctcctgtttt attatataca
     8521 acaatatgat gtatttcaac tcataaaata taaaaaaact tcaaatacca ttacaaatac
     8581 aacaacttgt tgtactatac tgagatgggg gtgtattaat gaaacagaaa caatatgcaa
     8641 aggtcattag agaaaagcga aaagctctcg ggtggacaca aaaagaatta gctgaaaaaa
     8701 tcttctctac acaacaggca gtagcaagat gggaaaattc tgtaacagag cctaacctcg
     8761 atagcttaac cgctctttct agagccctag gaacccctgt aagccatttt ctagacaatg
     8821 ttgtcgtaga ttatgaggaa gagtttttgg ctctctatcg ttctcttagc actgaagatg
     8881 cagttcgaac aattgactat atgaagctat taaaaaggca agaaaatgaa cgcaatcagc
     8941 tattgaaaga ttgaaaaata aataacccac cgaactttaa cggtgggtgt attgagatga
     9001 aataagatta agagctatgg ataacctgtc tagtttaata caattgggtc ttttctcttc
     9061 cttactctcc gtccatcatc tcttgttaca cttgtaaatt gataaagagg aactaattca
     9121 actcctgata atatcaattc ttttattact tcatctatcc ctgctccttt tgctaggtag
     9181 actaaaaaac tactacttgc tttcacattg tatagtctct taatatcctt agaagctcgt
     9241 tcaagagtga atccttgttt aacaaagtag cctctgtttt cttttaaagc attttccacg
     9301 ctgttattcc caacattacg tagacgttca caaacagtgt tagtaagttc tttctctgtc
     9361 attagatatg ttccttgcca cgataagccc tgtaaaactt catgtgcttc atctaaaatc
     9421 aattgttttt ccttgctaag ttctgatcgg gaattttgag gaaatactct tttagcctct
     9481 ttttcgttaa aacatatctt aacccattca taagaaaaat attgatatgt aaaatgaaat
     9541 ttttccagaa gtggaaggat atcttcattc aatttttgaa tcacagaagt tgcattaaaa
     9601 acgtctaatc gatagacatt gcttctctta tgattaaagt ttcctaacgc tttctcttcc
     9661 tttaacctat ttaggtattc gagcatcttc aaaggaacat cttcatcatc taattttttt
     9721 atcaatccta taaaagtcat aagtgatagt aacttattac atttatctat gtcataagtt
     9781 ttaccatagt aaaaactcat ttttttagct aattgttccc ccgacaaaat acaagtcaca
     9841 ctttccttac tatcatcaaa aaaattaaca tcagaaagca agacatcata gacacgtcgc
     9901 atttcctcta gataattcct tattgtcctg aaaagtttgt ctttcattga ttcaagagtg
     9961 tcaaaaagta cttttgattc ctctttcaat tttcgaaaat gtgtaggata caagtctagg
    10021 ttctctaata gccaattaaa tgtttctacc cgactgtctt tctttaaaat tagcatcaca
    10081 actccaataa aattttcact gatatcacaa ttactggaat gacaataaaa aatggaatgc
    10141 ccagttttac tggtaaaaat actagcagag ggattatgat cgttgtgaaa cagacatctt
    10201 aagtttttac ttgacttaag taatttattc atatcaatgg ttaacaatct ttcataaatc
    10261 tcattaaaag acatgtcgga ggaatcaaac aggcagtctt taaaccactg tttcatttct
    10321 tctttgtcgt cattttttat caacttaaca aaatcggttt cattgactag ttcatactct
    10381 ctccctgaat cactttgaca atttttagaa catgtcatgg taaaatcaat cggaagctca
    10441 gtaatatcta acatgttgtc ttcattaatt attatcactg catctgactt atatcctcca
    10501 aaaaacattc tattcgaagc atttacattg tcatcacacc cggggatgtt ctttttcaag
    10561 tattcgtaaa cagcaaccat tttaccatag tcagtaattg cttcttttaa tagaaagaca
    10621 atcttgtatt tttctagatt ttcagagtac cgaatacttt tttgtatcgc aaacgcagaa
    10681 ttatgaacta aattgataga taaaaccttt tctatgctta agtatctact atcatcttta
    10741 ctcaaatcta ctaccttccc cttctcatct ttaacagtgt tatcgacatc cagaataatt
    10801 actctggttt ccacaaaact ctccttgtca ttgcctttat tctttgtctt gcttggaata
    10861 aatgattgtg atgaatttag tatctctaca aactcatctc ttgtaacttc tctatagtta
    10921 tctaaacacc tatctcttac atcagttttt tctttttttg taactggctt ctctaataat
    10981 ttttctttat ctacataaat tggaatatta atcattgatg tttccatttg tgtttcctcc
    11041 ttataaaatt ctgttaaaga ctaaaacata cagataataa aaacaaactc tttattacta
    11101 tatgttttag tcttatttgt ttactcaacc tttataccgt tccatgaaac tatcaatatc
    11161 agatttttta aatctaatga ccgtatcaat ttttataaca ggtaacccgt attgagaaac
    11221 atattttcta atcgttccta ctgatacacc tagatattca cttgcctgct gatagtccat
    11281 atactctaga gtgactccag aaataatgtc ttctagcata ggctttagca ctgtaattat
    11341 ctctttcact tgttgttcaa cttgtataga aacaatgcta tcaatgattt gtagagacat
    11401 atttccccct cctttcgtga ttgcttgaac aaattttcta agaattatct tcgtattttt
    11461 tgctcaaaat aaaagtattt tgttattaac cgattaatca aacaaaaaat gattaccagt
    11521 tcatcgacat acacataata cctcgataaa aaagaggtgt caatatcttt gtaaaattta
    11581 tttacaacac ccctttttcg aggtatacta attttaggag gtgtggtcaa tatgataaaa
    11641 cgtccaccaa taaattattt agaacgaaaa aagatactcg gaacaaaaat aaaagctata
    11701 agaaagagta aaaaattaac acaaccagca tttggtctta tgattaacaa cggtcaatta
    11761 attgacaaaa aaactatcta cgaatgggag aagggaacct atttaccaat accagagcga
    11821 ttatcccgaa ttgctgattt gggaaatatg agtatagagg agttagtttg tggcaatgta
    11881 gaagaatata ttttgggaat tattctttat agagatagca ttgtactaga tggtataaca
    11941 tttccagata aaaacctgtt ccagcatctt cgtcaacagt tcccaccagt acactctaat
    12001 ttagatacat ggctggatag atattccaaa ttagaaccag agatgcaaga atttattgct
    12061 aacaagactt gtaataaagt taaaaatgaa aaaattagtc ttttcaatat cttaaaaata
    12121 gaagaattat tcatcaatgc tattgtagaa gaatttgaca ataacattct tttcctcact
    12181 agcagtatag aagaactact agaaagaatg gtagatgaat ggctacctat tcaattgaaa
    12241 gacatgtctt atcccgaaga agctgtgaga gaaattactg ataatataaa caagctagaa
    12301 caaacgattt catcaattgg gaaaaaatac actaagaaaa aaatgaaggg aggtgatacc
    12361 atctagtggt aagtactcct tgtaaactaa gaggagatga tttcatggca aaaatatcaa
    12421 agtacaaaaa gaaaaacggt caagtggcgt ggatgtataa aggacacatt gccaccgatc
    12481 cacgaactgg tgaaaaaata aatactacga gaagaggttt tagtagcaaa caagaagctc
    12541 aaaaagatta tgacgagtac agacatcaaa tattatacgg tgttaaaaag aaagcacctg
    12601 atatgacatt tgaagacctg tataatgaat ggataactca tcagcgtacc agtgttaaag
    12661 cttcaacaat cgcaatctca gtaagatacg caaataatca aatacttcca gcatttggta
    12721 agcttaaact atcgaatatc tctgtcccat attgtcaaaa agtggtagat gaatggcaca
    12781 gtaaatatga aagttacgat tatatgagaa aacagactgc acaaatttta cgctacgggg
    12841 ttgcaatgca atatattgac aataatccta tggaaaaaac acttcttcca cgaaaaaaag
    12901 agtatgagaa aaatcgtaaa ttttactcaa aagaggagct taataattta ctggatgctt
    12961 ttaaagattt tggtaacatg aaacaatacg ccttcttcag attattggca tacacaggta
    13021 tgagaaagag tgaagtactc gctttacagt ggaaagacat agacacgttt aataaagaac
    13081 tacatgtcaa taaaactctt gctgtagatg aatttggtaa agttataatt caatctccga
    13141 aaacaagagc ttctagacga gttatctctt tagatactga gactctttct atcctcaaca
    13201 actggaaatt acagcaaaaa gaagagtatt taaaacttgg atacaatact agctctaaag
    13261 agcaacatgt ttttacaaca gttaaaaaca ctctatacat tccaaacact gttaatgatt
    13321 ggttaagata tattttgaaa aaatataact tgcctcgtat tacacctcat gggtttagac
    13381 atacacatgc tagtttatta ttagaagcag gagaatctgt caaggtagtt caacaacgat
    13441 tagggcatga aaatagtaaa gtgacattag acatctatgc acatattaca aataatgcac
    13501 ctaagaaaac aggtcaagac tttgctgata tgatggctca tcagtaaaag agctggtcaa
    13561 aatctggtca tttctagtat acaggcaaaa caaaaaagct agaaccctta tatatcaagg
    13621 gttctagctc ctataacagg tttacccaac actgccttcc atctcataac tgatcaatcg
    13681 attgagttcg actgcatatt ccattggaag ttctttggtg aatggttcaa caaagcccat
    13741 gacgatcatt tcagttgctt cagattcggt caggcctcgg ctcatcagat agtagagttg
    13801 ttcttctgag atttttgaga ctttggcttc gtgttctaaa gagacttggc tgttgtggat
    13861 ctcattgaat gggatcgtat cggatttcga ccattcgtcc atgatgatcg tgtcacattc
    13921 gatatgagag atcgaacccg cactgttttt ggcaaaggtt acttgtcctc gatagtttac
    13981 ttctccgccg tcttttgaaa ttgatttaga gacgatagag ctagatgtat ttggtgcatt
    14041 gtggatcatt tttgcacccg tatcttggat ttggtttgct cctgcaaagg cgatggagag
    14101 catggtgcct cgtgcacctt ttccatctaa gtaaacactt gggtatttca tcgttgtttt
    14161 tgcacctagg tttccgtcga tccattcaac ggttgcgcct tcgtatgctt ttgctcgttt
    14221 ggttactaag ttgtacacat tgtctgacca gttttggatc gttgtgtaac ggcaatacgc
    14281 atcttttctt gtaaagattt ctacgatggc ggcatgcagg ctgttacttg aataagtagg
    14341 tgccgtacaa ccttcgacat agtggatgct tgctccttcg tcaacaatga tcagcgtacg
    14401 ttcgaattgc cccgtgtttt ccgcattgat ccggaagtac gtttgtaatg gaacatcgac
    14461 tttgacgcct tttggcacgt aaataaaggt cccacctgac catacggctg aattcagcgc
    14521 tgctaatttg ttgtcggttg gcggtacaag ttttgaaaag tactctttga ataattcagg
    14581 gtattctttc aaagcagagt cagtgtcagt aaagacgatt cctaactttt cgaattcatc
    14641 tttcatatta tggtacacga cttctgattc atattgtgcg gaagcaccgg ctagataagc
    14701 tcgttcagct tctggtatac caatcttttc aaatgtatct ttgatttttt ctggtacgtc
    14761 ttcccagtca cgagcgggtt tgtcacttgg tttttggtaa tatttgatgg catcgaaatc
    14821 gatgtctgaa aggtcggggc cccatgtttg cattggcatt ttgttaaatg tttctagaga
    14881 tttcagacgg aattcaagca tccattctgg ttcgcctttg attcttgaca tctcacggat
    14941 cacttcttct gtcaagcctt ctcctgtact gaaaaccggt tcgacatcat cgtgaaaccc
    15001 gaatttatat tcttctaatt ctggtacgcc catgttctca ctcctcttcc ttgtggtaat
    15061 gatggaaagc tgcggtacca tcgttttcca ttgcttttcc tagtgctttc caggcaagtg
    15121 tcgcacattt gatccgagcg ggaaatttag ctacaccacc aagcatagca gcatcgccta
    15181 attggtcggg atctttgact tcttttcctt ggacaagctg tagaaagtct acagttaaat
    15241 gttctgcttc ttctattgat tttccgatga cggcgtctgt catcatcgag gcacttgccg
    15301 tactgatgga gcagccactg ccgtcaaagg cgatattttt gatgattccg tcttttacat
    15361 cgacttgcaa ttcgatcaca tctccacatg tggggttgtt caattcgatc ttgcttgtcg
    15421 agtcagtcaa gcttccacga tgatgcggat gggaagaatg atccaagatc acttgacggt
    15481 ataaattgtc taatttagat agtcccatgt tggaaaaact cctttgttgc catgattgct
    15541 tcaactaaac ggtcggcgtc ttgcgttgtg ttgtagaaat aaaagctcgc gcgagcagtc
    15601 gctgatactt caaggtactt caatagcggt tgcgcacaat gatgacctgc tctgacggct
    15661 accccttcca tgtctaaagc tgtcgcgaca tcatggggat gtaacccatc caaattgaat
    15721 gcaacgactc ctgtccgaaa attcgggtct tgtggaccat aaacagtcaa tccatcaatt
    15781 gcttgtaatt ttggcaacac ataagcggct agttcttctt catatcgatg gatattgtcc
    15841 ataccgagtt tttgcaaata atcgattgca tggcctaatg cgatagcgcc ggcgatattt
    15901 ggtgtccctg cttcgaattt ccaaggtagt tctttccatg tactgtcgta taattcgaca
    15961 aaatcgatca tttcgccacc aaattcaaca ggttccattt cttctaacca ttttcgttta
    16021 ccatataaaa caccaatacc tgttggtccg cacattttgt gtccgctgaa agcaaagaaa
    16081 tcacagtcta gtgcttggac atcaatggcc atgtgcgggg cagattgagc accatctact
    16141 acgatgaccc cgccgttttc atggacaagt tcagctaatt cttgaacagg attgaagaca
    16201 cctaagacat tggatacatg agcaatggag acgattttgg ttttgtccgt aatctttttc
    16261 gctgcatcct ccatatccag gaagccttct tctgttagtt cgatatattt caagacagca
    16321 cctgttcgtt ttgccaactg ctgccacggg ataacattag aatgatgttc catgtaagag
    16381 agcactatct cgtctcctgc tttgatatag cggtcgccga aggttctggc tacccaattc
    16441 aagcttgtcg tcgtaccacg agtaaacagc acttctgctg tttcttttgc atggatgaac
    16501 gcccgtactt tttctcttgc ttgttcataa tcatgggtcg cgcgttctgc taacgtatgg
    16561 acaccgcgat gaacattggc gttatcgtgt tcgtaatagt acgctaatgc ctggagtact
    16621 tgttttggct tttgggtcgt cgctgcatta tccagataaa ctaaaggttc atcattgacg
    16681 tcttgaaata agataggaaa atcattgcgt agctttttag catcgatcat ccattcaact
    16741 tcccttcgat tacttcgact aattctttcc gaacttgttc tacagggatt gctgttaaga
    16801 cagaaccgag gaatcctcga atcactaagc gctctgcttc ttctttatgc aatcctctac
    16861 tcatcagata gtacatttct tctggatcaa ctcgtcctac actggcagca tgtccagcag
    16921 ttacttcgtt ttcatcgatc aaaagaatag gattcgcatc accacgtgct ttatcagaaa
    16981 gcatcaagac acgactttct tgttgggcat ctgcaccttt tgcccctttc aagatgtggc
    17041 cgataccatt aaaggtcaat gttccttttt ctcggatcac tccgtgttgc aaaatatgcc
    17101 cgatcgtatg aggggcttta ttggttactc gtgtatcgat tccttggatt tgtctgcccg
    17161 agctgattgc cacgattttg acttctgcgt gtgcaccttc tcctgctaaa tctgagtcaa
    17221 agtcagcgat cacatgaccg tcattcatga caccaattgc ccagtcgaca gaagcatctc
    17281 gtaaaatgtg cccacggcga ttcatataag aagtaatatt ttctcctaat tgatctacgg
    17341 ctgaatattt gatttttgaa ccagctttag cgatgacttc cacgatgata ttacctgatg
    17401 attttgctac ttgttctttg gttgtctgga aacgttccag ataagaaaat tcactatgtt
    17461 catctgccac gatcaacaca tgcttgaaga agtgctcatc ggatgcgcca tcttgaatga
    17521 ataaggactc gagtggttca tcgatcacga catttttagg cacatacagg aaaataccgc
    17581 tgttcataaa agctacatgg agtgcagtca attggtcttc gttcatgttt actgcttttt
    17641 tcatataata ttcttggact agttctggat attcgatcat tgcagtgaac aagtcggtaa
    17701 aaatgactcc tttttctgct aattccacag gcagttgttc aaaaatcgtc catgaacctt
    17761 gttggacaag cacaggattg tctttcattg catcaaatgc cggaatcgtg cctgtttcac
    17821 tgatggtttg tgtttctttc acatcaaata acgaccagcg atggaatttc acccgatcga
    17881 tatgcggcaa tggcagttca tctgctttcg ctagtgcgtc ttgacggaag gttctcatcc
    17941 aatcaggttc gcctttactt aaagaaaaat catttaccgc gtcaagataa tcgagccagt
    18001 ttttttcttt cattcttgct cccccttacg cttcttcttc tttatagtcg attcctaatt
    18061 ctttactgat accagcgtag ccttctgctt ccagacgttt agctaggtca gcattccctg
    18121 tcatgactac tcggccttcc atcatgatgt gaacgacatc aggtgtgata tagttcaata
    18181 atcgttgata gtgggtgatg atcaatgcac cgaaattgtc tccgcgcatt tcatttactc
    18241 ctttagcaac gactttcaaa gcatcgatat ccagacctga atcgatttcg tctaaaattg
    18301 caaatgtagg ttctaacatc aacaattgca ggatctcatt ccgtttcttt tctccgccag
    18361 aaaaaccttc gttcagataa cgttcagcca tttcttctgg catatttagt aaagccattt
    18421 tttcatctaa ctttttcaaa aatgccataa cagaaatttt gtcgttttca tcacgtttcg
    18481 cattgatcgc tgcacgcatg aattccgcat tcgtgatacc tggtatctca cttggatatt
    18541 gcatagctaa aaataagcca agtcgcgcac gttcatctac ttccaagtct aaaacatttt
    18601 tcccgtcaaa caaaatttcg ccttctgtta cttcatagtt tggattgccc atgatagcgg
    18661 cagataaggt agattttcct gtgccgttag gtcccatgat ggcatggatt tctccggttt
    18721 tcattgttag gtttacgcct ttaaggattt ctttttcctc gatcgacaca tgtagatttt
    18781 ttatttctaa gacagacatg cattataccc ccaaattctc tttcgttctc actcatttta
    18841 gactaattga gaatgaagcg caatgacctt ccttactaaa atcaaatatc ttttatttat
    18901 tattaaacaa ttttgatttc taaattagaa taggtataaa aaagatgaga aataagccat
    18961 tacagactta tttctcatct tttttgttcc ataccttatt ttgcatcagc ctttactggt
    19021 ttaacagagc cgccccattt gtctgtgatc cattcttgga cttctttgcg gtgaagcact
    19081 tcaatcagtt ttttgatttt gtcactgtct tcatcacctt tacgagtcgc aataatattc
    19141 acgtaaggag agttgtcctt ttcaagcaat acggcatctt ctaatggatt caaccctgcg
    19201 ccgtaagcga agtttgcgtt gattgcaact aggtcacctt catcattttg gtacgtagaa
    19261 gctaaaagtg atgggtcgat cgtatggttg aacttcaagt tcttagggtt ttcttcaata
    19321 tcatcgaatg ttgctgtttc cagatctact ccatctttga ctttgactaa gccagcatct
    19381 tgtagaattg tgatgatgcg tccccagtct gattcagaat ttgaagtaat gattgttgca
    19441 ccatctttta attcggaaac atctttgact tttttagagt acaagcccat tggttcgatg
    19501 tggacagcac cggcattgac aaagtcatat cctttttctt tgatttcttt gttcaaataa
    19561 ggaatatgct ggaagtaatt ggcatcaatg tcgccttctt ccaaagattg gttcggtaat
    19621 acatagtcat cgaatttgac gatttcaaga tcgattcctt catctttcaa taatggtttc
    19681 acatgttcca aaatctctgc gtgcggtgtc ggtgaagcgc cgactttcaa tgtcgtgtcg
    19741 tctgctttat ttgctgaatc tttgctgtcg ctgttgttac cgcatgctgc taatcctaca
    19801 gtcagcaaaa gcgctgctgc aaatccaaaa attttctttt tcatatccta catcccccta
    19861 tatcctatta tcttttgtct gttttcttag ttaagaaatc accgattcct tgaacgataa
    19921 atacgattag taaaataatt aaagtcgcaa cgaatgtcac tgttagatta ccacgctggt
    19981 agccttcctg ccaagcaaga cctccaagtc cacctgcgcc gatcgcgccg gccatcgcag
    20041 taaatccgat catcgagatc gttgtaactg ttaatccaga aatcaatgcg ggaatacttt
    20101 caggtatcaa gaccttccag atgatttccc agtaacttgc tcccattgca tctgctgctt
    20161 ccagtacacc agggctgact tcacgaaaag caatctctac tagacgggca taaaatggtg
    20221 ctgcggataa aacaagagct ggaatggctg cttgcgcacc tagcatagtg cctacgattg
    20281 ctttagtaaa tggaatgatc aaaaccatca ggatcataaa tggcgttgac cggaaaatat
    20341 tactgatgat cgatacgatt ccataaatga ttcgagcata cggtttgttt ttgcgtccaa
    20401 tagagtaaag gatcaatccc aaaactaatc cgatgatcgt cactaagacc attgagatta
    20461 atgtcatata tagtgtatca aggatagcct gattcatcgt ttccgggttg atttgtttaa
    20521 aatctagata tgtttctgaa aagcttttat ccacgatgga tcacctcaat tcctactcct
    20581 tgttctttga tgaacacttc tgcttgatct aattctttgg tttcaccagt catcaagaca
    20641 gtcaatgaac caaaggaacc ttctttcact tgtttgatct ttccatacac aacgttgaca
    20701 tcgatgttat agcgtcgaat cgcttgggaa atgactggct cgttggcatt tctttcgcta
    20761 aaggtcaaag ttgccaaacg gccgcttgga ttttctttga tgagttcagc taatagttct
    20821 gtcgaatcag cttctggttc gatgtcttgt tgtacaaagc gtttggttac ttcttttttc
    20881 ggttgtctga agacagtcaa tacgtctcct tcttctacga ctttccccaa ctccatcaca
    20941 gcgactttgt tgcagatttt gcggatcaca ttcatttcat gtgtgatcaa gacgatggtc
    21001 aaattcaatt tcttattgat cgctaacaat aagtctaata cttcttctgt tgtttgcggg
    21061 tccaatgcgc tagtagcctc atcacaaagc aggatctcag gatcatttgc caatgctcgt
    21121 gcgataccga cgcgttgttt ctgtccgccg gaaagttgtg aaggatatgc ttgtccgcgt
    21181 ccttctaacc cgactaaacg caacagttct tctgcccgtt ctttacgttt gctctttggt
    21241 acgccagcta attccagcgg cagctggata ttttcaagta cagttcttga ccataacagg
    21301 ttgaaatgct ggaagatcat accgattttc tttcggaatg tacgtaattc tttgtttttt
    21361 aattttgtaa tatcttgatc gtttacgatc acttcgccgc tcgtgggaag ctcaagtcca
    21421 ttcaggagac ggactaatgt actttttcct gcgccagaat agccgacgat tccataaata
    21481 tccccttttt caacgtttag tgaaacgtca ttgacggctt ggatgtttcc gtttttccca
    21541 ttgaatgtct ttttgacatt cgttagttgg attaatgaca tgccattcac atctttctct
    21601 tataattttt caaacaaaaa agccttcgcc ctcttgcctt aagcaaaagg acgaaagctt
    21661 gaacttccgt gttaccacct tgatttaccg ttacttcgca ataacagcct cttccagtac
    21721 ttggacttag cttctttccg tatactgtcg cgctgtaacg ggcactcccg tagtaagttt
    21781 gcttacgctc gcttactctg ctctaagacc atcttccatc tcattttcgt tacccatttt
    21841 cagcaaacag ggctctcttc aaacgtccgt gacatgtact cttcttttca aagctttctc
    21901 gtttcatata ggattgctta tgattatagc aactggaaga atcagtgtca acttttttca
    21961 agtgattttc tgattttata attcgtcaaa ttcttttgga tcaacatctt tgaaacttaa
    22021 gatccacgca ttcatttcat ctgaatcatt caagatattg atatcttcac cgattttatc
    22081 attaacagaa gaaactgtac ccgttagcgg gctggcaaat tcattgaccg ctttttccgc
    22141 ttcaacttcg atcagaggtt catctttttt tagcgattgt cctgcttttg gcagattggc
    22201 aaacgtgatg tctccaagtt cttcttgcgc ttcatttgtc aaaccaacac agtattcttt
    22261 tccattaaat aagatccaaa ggttgtcctt tttcttcaaa tgcttgcctg ccattttata
    22321 tcagttctcc ttcataaatt ttttcattga atccaattgc aacaagctgg tcctctcgta
    22381 agatcagtgg tcgcttgatc agcataccat ctgtcgataa gacttggctc gcttttgaag
    22441 ccgtaaactc gcctacttga tctttcagtc caagttcccg atatttcatc ccgcttgtgt
    22501 tgaacaggcg acggattggt acttgactcg tttctagcca agtctcaatc gttgaggcct
    22561 tcggtacttc tttgatcata tcaacggttt gataactaac gccatgctgg tctaaccacg
    22621 ctttggcttt tttgcatgtt gaacatttcg ggtaccagta aaaggtgtac aattttctta
    22681 cctccttgaa gatcttgcag gtgcttcatt ttggtatctc atcgataata tcaacccgat
    22741 accgatcatg ttccctaaaa tcgaggatcc tccctgacta atgaaaggca atgggatccc
    22801 tgttaaagga agtaatccga tatttgctcc aatattctca aagacatgga acagcagcat
    22861 catgatcaaa ccgcttgcga tataggcgta aaattcatta ttcgtatcga aacacacccg
    22921 aatcatacga tagattaaaa taaaatacaa gaaaatgacg aatgcaccac cgataaagcc
    22981 gaagttttca ccgataacgg taaaaatcat atcggactca cgaacaggca catagatatt
    23041 gcttacgttg aatcctttac caaacaagcc accggtacca attgccaaaa gtccttgggc
    23101 cggctgataa ctcattcctg acgtatcatg gaaagggtcc agccatgaat caatacgtgc
    23161 aaactgataa gatttgaatc caactttata aagcaagtct cttccgcctt cagtcgtaac
    23221 caagaagatc gttcctgctc caacgactac tgccaagatt actacaggtg cgatgatgcg
    23281 ccaagagatt ccagacatca ggaaaatccc gccaaagatc gcaagaaaga caagcatcgt
    23341 tccaaagtca tcttgggcca tgatcaatgc taaaaccggt attgtcacga tcaagagctt
    23401 cccaatcagc caaaagtccg atttcatcgt ccgttctttt acttgcgtat tatgtttagt
    23461 tacgatcagt gccatcatca agatgtacgc aatcttcatc aactctgctg gctggaaagt
    23521 aaacgcaccg aatcgaaacc agtttttaga ccctgttgaa gcagctaaat tctgatcata
    23581 gaatttgagc aagagtccca ttaccactaa ccccaaacca taaaggtaag gagtcagttt
    23641 ccagatccat ttggaattca aatgcatgat gacaacgatt gctgccgctc caactaaata
    23701 ccagacaact tgcatcccta cgcctttcaa gactgctgga ttgttcggat catggctaag
    23761 tgctacatat aatgagagca gaccaatcaa acataacaga aagactggta aaatcacgcc
    23821 ataatcaata cgattatcgt tcgaagcttt taattttttt tccatgtttc atcccttttc
    23881 ttaaaaacca tactgctgat tattatagcg gtccagttag ataatggaaa gtctttccat
    23941 agacatttgg gaaaaattaa ctttccgttt gtgcagttgc ttgagcaaat gcagtacaaa
    24001 agcctactgc ttatctttag tgtatcatag aacttttttt gatacatgca attatctacc
    24061 agctgagatt ctcctcgctg tgagaagttt ctgtgctttc attgtatcga aggatctctt
    24121 cggcaatctc tagcagctga tcagaaacca gattggttcg ttggatgaaa taaaaatatc
    24181 gatggaaatt caacggagtc attggcacat tttctggaac agagcgctta gacaaaatcg
    24241 agcgaccgat tccttccttc agcaacgcaa caattacatc gttacttttc acgatcatct
    24301 tcttatcttg gatattcatc tcttcaaaat aacgctgcgt gtaatgaaaa acaccagagt
    24361 ttgcttctct tacaagccac aatttgcttt ttgggtcccc agcgatgact agctggtctt
    24421 ccatcaaaga gtatctttgt acgccggaag tctctaatgg cttttcgata aaaccaaaat
    24481 cggattcatg tttcgctact tgttctaatg attcatgaga attcgtgatt tcgatctcaa
    24541 aatgcacttt aggaaacctt ttgatcagat gtttcatcaa ctgaggcaaa agatagacag
    24601 caaaggtgtg ggaagcaacg atccgacata cttcttcttc attttgttca ttgagcaatt
    24661 tttgctgagt ttcttcccat tcttctaaca aaaccagtgt ccgttcatat aataagtcgg
    24721 cttgcttagt tggaagcatc tcttttcttc cgttacgttg aaaaagatcg atattcaatt
    24781 cccgctccaa ctgtttgatt tgattcgaga ctgctggttg agataaaaac agtacttctg
    24841 ctgctctgga aaaatttctt gtttcatata ctgctcgaaa agtcgttaat aacttaaaca
    24901 tggcaccact tccataactt tttatgataa ttactataaa aactatttga tttaaatata
    24961 caaaaaacca tctataatag aaatgtacaa caaaacagtt gctgatccaa ctagtaactt
    25021 agatgaagac aatcagctgt ctgcttgctc gtaatcatac attcctattc attttacaat
    25081 gtattcgttc atcttggtac taaaatctat taaataaaaa ggagaatatt atatatgaag
    25141 aactttttga aaattattcc gatcccgatc tgcgggttga tccttgggtt agcttccctt
    25201 ggaaatctgt ttaaagacta tcaccatgtt gctttaggca atctaactgg cggtatctct
    25261 atgattctta tgatattcat ttttgttaaa ttgtttatct tattcgaaca cacgaaacaa
    25321 acgttgcatg atccaatcat cgcctccgtt tcaccaactt ttacgatgtc actcatggtt
    25381 atttgtactt attttgtttc atatgaaagt attgcaccaa ttgtcaaatt catttggctg
    25441 tgcgctgtta tcttccaagt gatccttgtc ttttatttca attatcacca tgttatcaaa
    25501 gctgatcttt caattgaagc aatttatcca agctggttta tcatttacgt tggatttggg
    25561 gtcatcactg taactgccgg gaacttcttc ccacttattg gaaaaatttt cttttggatt
    25621 tcattgatct gctatgcgtt cttattgccg atcatcatca aacgtgtctt tttcgtaaga
    25681 aatatggctc atccgacacg tccgctgatt acgatcgttg cagcacctgg ttctctttgc
    25741 ctaacaggtt atcttaaaaa ctttgctgaa cctaattttt atcttgtcgt agcattgttc
    25801 gctttatctc aagtattgta tttcgttgtg ctgtctatgc ttccacgttt gttcaagctt
    25861 cgtttttatc caagctatgc agcctttaca ttcccgcttg ttatctctgc aacagctata
    25921 tttactactg ttcattactt caacagttta ggtatctata gtagcgtatt ggatttctta
    25981 aaagttgcgg aatgtctgtt tgcaagtgta gttgtcttct acgttcttgc tcattacgta
    26041 cgtttcttaa ttaaagaaca tagcaaacat ggaaaatttg tttctaaaaa aatcgcttaa
    26101 taatcgattc aataggttgt gaaaaagctg ttctgcatca agtaataaga acggccaaac
    26161 aaaaacagct gttcatgttt ttgtactggt tgggcttatt accgcagatg caagcttttg
    26221 aacaccgttt accaagaggt cgtaaaagaa gtggtcagct tcaagaaata agaaggaatt
    26281 tacgaaaatt gcttctcaaa tttttgtgaa atttcggctt atttccgtag aagctacttc
    26341 tggaacaccg tttattcgaa acaagaggtc gtacaagact tttgtcacga cctcttgttc
    26401 ttttgtcaaa atactggttt agtgctacta tgttcgagta tgcttttagt atttattgac
    26461 gaaaggaacc gatcaaatga aatcattgtc acatccaata aaatctgtaa aggattcagc
    26521 ggtccgcgaa atcttacccg gtttactgct ttcttttgcc atcgctgcct tcagcaggct
    26581 tcttgctatt tatctgccac agttaggtgg agcgactatt gctattttat tgggtatttt
    26641 attaggaaat acttttttta aacagcctgt tctagcaatc ggcacaaaat ttgctgaaag
    26701 caaactatta gaattctctg tttttttact aggtgcaact gtcacagctc aaacgattgc
    26761 tcaaattggt gtaaaaggaa ttgtttttgt gttactgcaa atgtcagtca ctatcatcgg
    26821 tgcttacttg attggtaaaa aactgcaatt cagcgatact tcttctttga tgatggctgg
    26881 aggaaacgct gtttgtggtt cttctgctat tgcttcaatc gccccttcca tccatgcgaa
    26941 agaggaagaa aaaggacaga tcatcacact agtcaatcta ctgggtactg tgatgatgtt
    27001 gactctccct tttcttggat tacagttgtt tggtggaaat ctcattgaaa aaagtgcact
    27061 tttgggtggt acactccaat ctgttggtca agtagtcgct ggggcaagct tacttgacaa
    27121 ttctgttgtc gaattcgcca tgctatttaa gattctacgt attatgatgc tcgttgttgt
    27181 tgtctatctg tttgaaaaat tcatgcacaa gaaacaacca gctctgtttg aaacgccaac
    27241 tgatacgcag aaaaaacgaa aattaccgct tccttggtat gtattagggt ttgtgatctt
    27301 ttgtttggtc aacagcttgt tttctttacc tgtagttatt gaccaatcgg cacattttat
    27361 cagcagctgg tttgagatca ctgctttagc ggcaattggt ctgcgtttag actttgcaaa
    27421 attcatgaaa gaaggtacac gcttcttatc ttatggatta gctgtcgggc ttctccaaac
    27481 agtgatggct ttactattta tttggctgat caaagtttag aatgaacatg aaaaaacagt
    27541 tgtgattctc gcatggaaca atgtccgaat cacaactgtt tttaattttg cagatatcct
    27601 tctaacaaca acaattggcg tttgatttca accccatcta ttgcgtttcc catatatcct
    27661 gtcagttttc cattttgccc gatcactcga tgacaaggaa taacgattgg caatggattg
    27721 gttcgatttg cctgcccaat cgctcgcaca gctttcggac tatcaacagc aacggctact
    27781 tctttatacg ttcggatttc tccataagga atggtcgaca aagctttcca gacattttgc
    27841 tgaaaaggcg tacctctctt tatagataaa ggaacatcaa attcttttct ttttcccgca
    27901 aaatattctt caaactgttc ttgtgtgcgc gttaaaattc gctgattcgc tgattcgctt
    27961 tctgaaattg gctgaaaaga tacagcagtc aatccggatt catctgcatc taaccataaa
    28021 aagccgatag gtgtgtgtat tttcattttg tttgctccta gtcaatagac tggaacttcc
    28081 tcctttttct ctatccaaaa ctacttgcca actaataaaa attgttctta aaagtttgat
    28141 aaaccgagga aacatggtaa actaaatacg ttagtttaca aaaagaatac ctgttctttt
    28201 acgtaaaatc aaattttaaa ggtgttattt aaggtttatt aaattttgaa tgtaaaccat
    28261 atataaacat acgattgaaa ggatagaaac gatgaaagta tcaattgttg tcccatgttt
    28321 taatgaagaa aaaactgttc ctcttttttt tgatgaggtt gaaaaattca aaggtgccca
    28381 tgagttcgaa tatttgttta ttgacgacgg atcaaaagac ggtacgttag cagcaatcaa
    28441 gaagctagcc tcagcttatc cttatgtccg ctttgtctca ttttccagaa attttgggaa
    28501 agaagcggct ctgtacgctg gattgcaagc ttctacagga gatttagtga ccgtgatgga
    28561 tgttgatctg caagatccgc ccgaactgct tcctgagatg atcaaccgga tcactacttc
    28621 tgatatcgat tgtgtcggca cccggcgttc gactcgtgaa ggcgagcctg cgatacgcag
    28681 tttctttgcg aaaaaattct accagttgat caataaaatc agcgatacag aaatggtcga
    28741 tggcgctcgt gatttccgct tgatgactcg tcaaatggtg gatgccgtcc tagaattaac
    28801 agaatacaac cgattttcaa aaggattatt tagctgggtc ggatttaaaa cagaatatat
    28861 ttcttatgaa aaccgcgaac gtgtggctgg cgaaacatct tggtccttct ggaaattatt
    28921 caactactcg attgatggta tcgtgaactt ctcggatgca ccgttaacga ttgcttcatt
    28981 tatcggcgct ttgtcttgtg tcggttctgg tattgcaatt ttgttcatta ttttgcgggc
    29041 attgttgttt ggtgatccta catcaggatg gccttccatg gtctcgatct tcctgttcat
    29101 tggtggaatc caattgttat gtcttggaat catcgggaaa tatattggga aaatcttctt
    29161 agaaacgaaa cagcgtcctg tttatatcat aagagaaaca gaaaaagtga agccaaatga
    29221 attgaagcct caccaataat atacgtcaaa tgaagtaaac atttttttaa atgaaaaagg
    29281 actgtgacaa aagtcttgtc acagtccttt tttccgaata aatggtgttc cagaagtagc
    29341 ttcttcggaa ataagccgaa atttcacaaa aatttgagaa gcaattttcg taaattcctt
    29401 cttatttctt gaagctgacc acttctatca caacctcttt catatcttat tacttcttca
    29461 ttgctgcttt tagtgctgct gctaatgggc tttcttctgg ttcttctgct tgtgcatatt
    29521 ttttcagcaa gcgtcgttct tcatgtttgg tcattttctt cttctgctct tttttatcaa
    29581 gcaatttttc tgtcgttcca tcgtatttac aacggaaata agcaccgttt ttaccttcga
    29641 tgatttccat tttccggtga cattgcgggc atcgatgatt agagactttt ggatcttttc
    29701 ttctgcggta gttgcaatct gaattggtgc agacatagat tttgccgtca cgtgtgtttt
    29761 tctcgcgcag attggcccca cattctgggc atttcttttg ggtaatcgag aaatcttgat
    29821 attcttgttt gcttgatttg atctcattca ccaagcgttt tgtttctttt tcgattccat
    29881 tcaagaaggt tcctgcttgt ttctttcctg cagcaatagc ttcaaggtct ttttcccagc
    29941 tttctgtcaa atctggtgtt actaaagagg gatttaccaa tactaataat tgcttacctt
    30001 taggagatac ttgcagtcct tgaggggtac gttccatcag ttcagatttg attagtttct
    30061 cgataatctc tgcacgcgta gctggggttc ccagactgta tttttccatt tgaccaagca
    30121 agcttgcttc tgacaatggt ttaggcggtg cagatagttc ttttttgatg gcgaaatcgg
    30181 gattgattct cattcctttt tcccatttga ctgtttccgt ctcagtttca gtttcgcctt
    30241 tccatcctgc ttggacgaca cgattttgcc gaaaaatgaa tcgttcttta ccaaattcaa
    30301 ccgtaacttt tgtttggctg actttatggg gttgagcaaa cagtcctaaa aaacgagaga
    30361 caatcatttg atagattttt cgctcttcat tacttaattt ttcataacgt gctctgtttt
    30421 cagttggcaa aagtgcatgg tgatcggtca ctttactgtc ttggaatact tttgtctgtt
    30481 ggacgatggc tccgtttttc aaatactgct tgacctcagg agcaaagtcg ctgactgctt
    30541 gcaatcgttc tttcatcgta cttttcatgt catttgtcag atatttgctg tctgtacgcg
    30601 gataagtaac gatcttatgg gtctcataca aactttgtac aagacttaat gttttctttg
    30661 cagaatagcc atagcgttga ttggcttctc tttggatctc tgttaaatca taaggcaatg
    30721 gcgcagattc cgtttttaat ttttcttgga cttctgtgac agttcctttg cttgtactga
    30781 tcaattgaac aagtttttgt gcttcttctt gtgtttttaa agcaaattga tttttttgaa
    30841 gcattttggc ttgttctttt ccagcttgca acgtgatcgt gaaatacgtt tgtggacgga
    30901 actgctcgat tttcttttct tggtctctca ctaatgctag tgtcggtgtc tgcacacggc
    30961 ctgctgataa attatccgcg tacttcacag ttaaggctct ggtcacattc aatcctacca
    31021 gccagtccgc ttttgcccgg gcaagagcag attcatacaa tgcatcatat tctttcgcag
    31081 gtcttagttg cttgaatcca gttttgattg ctttatctgt ttgagaagag atccataacc
    31141 gcttcactgg tttattgaaa tgcacatact ctaagatcca gcgagcaaca agttcccctt
    31201 ctcttccggc atctgtcgca atgactgctt ctgagacatc ttttcgctga gccagctgct
    31261 tgattgcttt taattgatgt cctgttttag gaagtggttt gattcctagt tttttaggga
    31321 tcattggcaa cgtgtccatt tgccagctct gccattcctt attcagatct tccggcattt
    31381 tcaatcctaa taaatgacca agggcccaag taacgatcac cttgggtcct tcataataat
    31441 ttttgtgctt ttgattagca ccaagcacct tgcttaggtc tttcgcaacg cttggttttt
    31501 ccgctagaat tagttgtttc ataaaattcc tttctgcttt ctactgtgat gggctgatga
    31561 tttttcaaca acgcaagtcc cttgtattgc tgtaaatcat cgtcacactc ttcacaccag
    31621 cgctcatctc cgtcattcca aaaggcgctg agaaagttac tttttgcatt gatatattca
    31681 taattttgat ggatttcgtt ccattgtttt tcgtacgctt gtcgtgcttc ttcgaaagac
    31741 tcgaatgttt cttcttcttc aatatcttct tcccagtctt caaaaaacca ccaaggctca
    31801 ttgtccccga acatggtaat tacttgatac atactcgtgc tccttctttc agcttttcta
    31861 gactcatctt agtcactttt caagaaagtt gcaagaattt tctcttataa aagggtcatt
    31921 taatgaacat cttaaaattg ttacaaatga atctgattgt ttaaggcaaa gtagcgataa
    31981 agttattgat catccaaaaa tagctgtctt ctggatcgat tgttggttct tttgtaaagt
    32041 atcctaaaaa acgtaaggaa agataaccgt ggatcatact acgaagttcc ctgcttcgat
    32101 gaactttttc ttctttcgtt aattgaaaag cctcaaatat ctgcaaaatg atctgattcg
    32161 tttcatggat tccatctaat aaaacagctt cattggtatg cggtacactg atcagtaact
    32221 catacactgc ttgatttgaa aaagcaaagg atcgataagt ttctgcatag atctgcagtg
    32281 cttcctgacc actttttccc acaagagccc gtcgcagctg gtcattaagt tcctgcagaa
    32341 gtttcgctgt tagcgctgtt ttgacatcac gaatattttt gaaatggtta tacagcgagg
    32401 gagccttgat atccaagcgt ttggctaaat gctgaaaggt tatttgctga acatccatct
    32461 cttctgctag ttctcgaaag cagtcgatga ttttctcttg agacagattt ctttttttca
    32521 tttccatgtt tcctctcata aaataaatcc ttcactcttt cagtttacca cgaaaaagaa
    32581 agagaaaaaa gagactttca ttgataaact acatattgta gtttataata aagagctgta
    32641 gatgaaaatt ttcagaaaga aggagtctaa ttggctgcaa gaataaagga aaaattattt
    32701 aggaaaagag aaacttggga acaaaacttg tttgtcttat ggtttggaac atttatggct
    32761 ggtatcggat ttagtttagt catgcctttt atgtcacttt acatagatac gttaggtaat
    32821 tatagtacgt cacaattgaa cttttggagc ggattgactt tttcatctac tttcttggtg
    32881 actacgctta tctctccttg gtggggaaaa ttagccgacc aaaaaggaag aaaattgatg
    32941 ctgttgcgtg cttcattagg aatggcaatc gtcatttctt tgatgggttg cgtgactagt
    33001 gtgtatcaat tagtcgcatt gcgtctgctt caagggattt tttctggtta tatcagtaat
    33061 gccactgccc ttgtcgcaac tgggacgcca aaagaaaaaa gtggtcaagt tcttggaacc
    33121 ttagcaactg gttctgttac aggaacatta cttggaccgc ttcttggcgg gatctctgct
    33181 tcagcgtttg gctatcgccc tacctttttc attacaggga tcatcttatt tttcgtcttc
    33241 ttgttgagtc tgtttttcgt ccatgaaaaa tttgtcccag tgaaaaaaga aaacatggtt
    33301 tctgccaaac agattttcaa agacttgaaa tatccacacg tcgtcatcgg tatgttcgtc
    33361 acaacgatga tcatccaagc atccaacaat tccattagtc caatcatcag tctgtacatt
    33421 cgccaattgc tgcatggaca tgggaatgtt acgttgatca gcggaatcat tgcttcgata
    33481 cctgggattg ccactttgat agccgctcca agatttggtc gcttaggtga caagattggg
    33541 agtgaaagaa tacttgcgat tggtttgggt tttgcgattc tggtttatat cccaatggca
    33601 ttcgtcacga atgtttggca attagctgcc ttacgttttt tgattggtat ctctgatgct
    33661 tgtctgctcc ctgctgtcca agcattgatc acaaaatatt cgcctcatca agctgctgga
    33721 cggatcttca gttataacca atctttccaa gcaactggta acgtagtagg gcctatgatc
    33781 ggctccagtg tttccagtgc atttggttat cgcggcgtct ttctttcgac ttctcttctt
    33841 gttttggtca acttcttgct tgtacgacac aatacacaag agatccatca gcaagaaact
    33901 gcagaagaaa aagcttcagg agtctccata gcttcagggc actctccttc tcatagacaa
    33961 taagcgtaaa tgaaaaacac tgcttgaaca gttgtcacag actgtccttg cagtgttttt
    34021 gtttaggcct gttttttcaa gaactcagat aagaggaata atcccttttc caaggtttct
    34081 tttttacaac agtaacctag tcgggcatgc ttcggtaaat caaaggcact tcctggtact
    34141 aatagtactc ctgtttcttc taataaattg atacaaaatg tctggtcatc ttcttcgatg
    34201 gctaatttaa tgaaagaagt agagacgtaa ttgggagcga caagttcaac tttcggttca
    34261 ttggctaccc attgttttaa aatcacaagg ttctctgtaa tgatcttttt gtttcgcgcc
    34321 aatatttttt ctttattctt caatgcatgt acagcaagat catctgacag gactccgccg
    34381 caaatcatcg tgtagtctcg atactttcga aaaacttctg ccaactcagg tccagtagct
    34441 gtccagccaa tacgaatacc tggaatggag taggttttgg atagggaatt ggttgctata
    34501 cctttttcat agacatctac gatcgacaag aattcacctt tatccgttaa aggcgcatat
    34561 acttcatcta tcaatacata tgcatctact gtacgagcaa tttctgcgat tttttctaaa
    34621 gttttccgat ctagcaatgt gcctgtagga ttgtttgcac tattcaaaca gatgattttt
    34681 gtttcaggtt tgactaaggc ttctagctgt tctaaatcaa actgccaatc ttcttcttcc
    34741 ttcaaatgaa caaagtcaac agcggcacct aaagatttgg ggatgtcata taattgctga
    34801 taagtaggaa gcatcgaaac aacatggtct cctgcttcca ctaacgcgta tagagctaaa
    34861 agattagcac cagtcgctcc attcgtttgt aagatgtttt ccggatcgac ggtttgataa
    34921 agagaagcga cttcttgttt gaaaacatct gatccttcga tccagccata gtccaatggt
    34981 tcgtttttgc gtttttcgaa aaatttactt acgctagtcc catctaagcc aacgagttcg
    35041 tctaatgtca atgcttcgat cgagctttgt gcaatatcat ataccgcttt cttttcccat
    35101 ttatttagcc attcttctac accgaaattt gcgattttca tgtttctttc ccccttatat
    35161 cttgatccag cctacagcaa gcaacccgat tgaaagcagt gcggccacac aaatcagccc
    35221 aatcattact ttttcttttc ccgtaatttg atgtttggtt tcacgacaag cgatccagta
    35281 gaagcaaaaa ccaggaagat aggcaatact acataaaagg acataagaaa atcctgctaa
    35341 aatgatgccc atcaattcaa aaactacagc aatcccaccg atcactactt gttttttgat
    35401 tccttctttt aaagaaaact ggacttgata gatcccgaca agtagataac aaatcaaaat
    35461 tgccgctgta cataaagaat aggcaaattg ataggcataa tcagtaacta agaaagtcaa
    35521 taagaataga ttagtcaaga ttgcagtaac aactaacgaa taagttgggg catttttttt
    35581 attcgttttt ccccaacctt tcggcaacag accgtctcga gccatcaaca tcgttgtttc
    35641 tgctgggagc atcgtccaag acaaccaaga accaatgatc gaaataatca agccgatatt
    35701 gatcagcgct gctccccaat ttcccacgat tccttttaaa atatttgcca tagcaggttg
    35761 tgaaatagtt gctaactctt cttgagataa gacgccgtat ggcaagatcg aagcaaggat
    35821 atagataaac aataaacaaa gcagaccaat gatcgatgct tgctgggctt ctgaacgttt
    35881 cttcgcgcgg ttggctaaaa cacttgcgcc ttcgatccct acaaagaccc acatcataac
    35941 catcaaacaa cctttaatct gcaaccagat cgttccttgc tgccctgttc cattcactag
    36001 attatcagat acgttacccc aaaaatcagc agtgaatata ttcactttaa atgcgataaa
    36061 tacaaatatt aaaaatagga ataatggcac taatttacag atcgtcacga ttgtattgat
    36121 gacgctcgct ccttcaactc cattgtttac taataaagtc agaccccaaa taaaaatact
    36181 tgcaaataaa atagaaggaa cattttgtcc acctttgaat atcgggaaaa attctcccat
    36241 ggcgctcatc agcatcgttg caaaagcaac atttcccagc cacgcagaca accagtaacc
    36301 ccaaccactg atgaagccac ctaatttacc aaatgaagct tccgcgtaac cgaaaatacc
    36361 accatctaga tctggacgct tttctcctaa atgattcagc gataatacca aagctaaaat
    36421 accaatccca acgattatcc atgaaaggat cgctggccct ggagctgcag aactagccag
    36481 atcacttgtg atcccaaaca caccgcttcc gattgacgaa ctgacaacca gagcaaccag
    36541 tccccatttg ctaatacccg tcgatttctt ttccatttcc atcaccctca cttataaaat
    36601 tgaacaaatc acttgcaaaa gattcccttc tattttgcaa ctgctcttgc ttaacaaaaa
    36661 gcaactttat tcatattatt ggatattatg aactttttac acaagtattt caagtataaa
    36721 atgaataaaa attaatttta ttgcaaaaaa acagctatgc tatccaaaag aaaaggtgtt
    36781 tcttttgtta gccatagctg ttttgattca tttaatatcg cttaaacgta ttgtaaaact
    36841 tttgtttctt gatatgcgtg gtcgatcaaa ccaccaccca gacattccat tccatcataa
    36901 aatacaactg cttgtccagg agtgattgca cgtacaggtt cgtcgaatac gacttctgca
    36961 cgattatcat ccaataagcg aactgtcaca ggaacgtctt gctgacgata acggaatttc
    37021 gctgtacact tgaattcttt tggcattggt tcattcgtcg taaagtggat ttcacttgca
    37081 tccaagcttg tggcatacaa tgcaggatga tggaaccctt gccccacata taatgtgttt
    37141 gtcgctagat cttttcctac aacaaaccag ggttcttgcg aatctcctcc gccaccgatc
    37201 cctagtcctt gacgttgacc aatcgtataa tacatcaagc cagcatgttg tcctttgact
    37261 tcaccatcaa gagtgaccat atttcctttt tttgctggca gatagttgct caaaaattgt
    37321 ttgaagttct tttcaccaat aaagcagatt cccgttgaat cttttttctt agcagtcgca
    37381 aggcctgcgc gttcagcaat tgcccgtact tctgattttt ccatgccgcc tagagggaac
    37441 atcgtttttg aaagctgttc ttgtgataat tggctaagga agtaagtttg atctttatta
    37501 ttgtctactc cacgaagcat gtggaccacg ccgttttcat cgcgagtgac ttgcgcataa
    37561 tgtccagtag ctacataatc ggcgccaaga tccattgcat aatccaagaa tgctttgaat
    37621 ttgatttctt tgttgcacat cacgtctggg ttaggtgtac gtcctgcgcg gtattcggct
    37681 aggaaatatt caaatacacg atcccaatat tctttttcaa aattcacaga gtaataagga
    37741 atcccgattt gagcagctac tttcgctaca tccttataat cttccgtggc cgtgcataca
    37801 ccgttttcgt ccgtgtcatc ccaatttttc atgaatattc cgatcacgtc gtatccttgt
    37861 tcctttaaca aaagtgctgt tacagatgag tcgacaccgc cgctcatccc tacgacaacg
    37921 cgtgttttgc tgttgtctgt catgatatca ccatcatttc aattagattc tgaaacatct
    37981 acgagttgaa ggtcgcaact tttcagtatt ttacattata cgtcatattt ctgaaaattt
    38041 catcccttaa ttatcaagtc gtaaaaatac tgttctactg gacctattca gtacacaaac
    38101 atgatagtca accaaaaaat cactcatctt ttgagcattc gatataaaaa attggcatac
    38161 tcataaaaag ggccagcctt tcggcaataa ggaataattt tataaattgt gaaaaactat
    38221 ttttcaaaat tgcttcttat cgcttaaagc tgcacgtctc atttacaacc ttttcttttt
    38281 agatgttatg agttgctcag ataagtgatt ttgtttactc taagaaaaaa gggaggcaaa
    38341 agatacatga attactttat cagtgatatg cactttttcc atgaacgctt attaggaaaa
    38401 aacgactttg ctccgcggct ctttgcaaat gtggatgaaa tgaaccaaca gttgatcact
    38461 agctggaatg cagtaataaa agaaaccgac catgtttatc atctaggcga ccttgctatg
    38521 catccgcaat atgaaaaagc aaatgcagaa attttggaac tggtcactca actgcaagga
    38581 acaatccact tgatcaaagg gaaccatgac agtcgcgctt ttttccgtta tttagaaaaa
    38641 aatgatccta ggcttactga cggaagtccc aaattttatt tttatgatgt aggtgccatc
    38701 gttaaattcg accatcaaca atattacttg actcattatc cgatgttgct cgggcctaac
    38761 gacactatcc gcaatcttca tggacatatc catcattaca gcgtacctat cgagaacgat
    38821 gtcaatgtag gcgtagacgc accggaaaga gaactcttaa aggaaaaact accatttggc
    38881 actccgttat ctgagcaaca aatcaaagaa atctatgaag caaagaggaa gtacgatagg
    38941 tcgtgaaaaa actgccctat atcaagtatt aaacaaataa agataattac tcatattttt
    39001 catttgagta ggcttattgc cacaggaaca ttaggatcag aaatggagtt gtaacaagac
    39061 ttctgtcaca actccattcc atactattcg tctttttgct catggtgttc ttttaccagt
    39121 tttttctgta attctttatc ataatttcgg gcagctgacg ttaaaaataa aacgattccg
    39181 cataataaaa tcccgattcc ggaaaacaag aacatttttt ctacccctaa acgatcagct
    39241 aatggtcctg caaataataa tccaattgga cctgccaggt tcatcaaaga gttgaagttc
    39301 cctaagacac gacctaaaac attcgattca taactctgct ggatcattgc catcagcagt
    39361 gtattgaaat atggcgttgc acaacctgct cctgcattca agataagaaa gtacaagaac
    39421 ccttgactat cgtttggaac caatccgctt gcaccgatcg tcaggcccat aatgatgtag
    39481 gctataataa taggtttcat tcggtctttc catgttccta taaaactgat cagtgcaccg
    39541 cctaagagca ttccgactgc gtagactact tccactgctc ccgcctgtcc aacggaacca
    39601 ccaaagtaat ctagcgtcat caatggatac agactgattg ctggcatgaa caacagcatc
    39661 acaaatgcac cattgatcgt tatgtaccat aaccctttat tatccatcaa ttgctgcagc
    39721 ccaaattttg catctttaaa aatagtaagc ggaacttcca atatttcagg agaaactttt
    39781 gggatcttca caaaaatcaa taagccgaca ccaaaaactg cccccaatac atctaataaa
    39841 ataaggtaat tgacaggaac gactgaaaac aaagccgcac ctagagctgg cgcaatgatg
    39901 aaattcgctg attggaccat tcctaactgt ccattcgtcc ttgttatgtg agaagatgga
    39961 acgattgtcg gcataatcga ctggatcgtt ggcatttgga atgtttgtgc gaccgaacgc
    40021 ataaacaaag acacaaaaac tagccaaatc gggaaggatt ctgaaatcgt tccgactact
    40081 gctaaaataa gcgcgaaaat cgctacaata atatccgtga caatcaaaag agctttttta
    40141 tcccagcgat ccactagcgg tcctacaaat gggcttagta aaaccatggg aatcattcct
    40201 agtaaagtag caaaactcaa aattgtcgcc gaaccggttt ctcttgtcaa ataccagatg
    40261 atcgcatatt ggacgaccat actagtgatt cctgacaaaa actgtcccga taaaaagaac
    40321 aaataatttc tcttccaatt cgttaaaacg accgactgtt cattttccat aaacatccct
    40381 cttttctttt tcattttgta tagcgtttgc acaacaatca ttatacggga ttcttttttc
    40441 aaaaaatacc tttttcccta aataacaatc gtttcaattt aaatttcttt acttagaaac
    40501 aataaatcag caaaatatta aaaataacaa catgtgttaa atttaaaaat aaaaaagaca
    40561 actaatttgc gtcgtcctta caaagttagt catctaacaa taggccgttt caaaactagt
    40621 tgtcttttta tatccacaga tcattcgact ttttcgaata acccacggct aatcatccca
    40681 tccatcagaa aataaaattt atcttggctc attttctgtt ttggatcttt gaaaatattg
    40741 actgctttca atccatttgc tgtagtgatc gacattttca atgtttgaat atcttttgat
    40801 acagtgattt ttaatttgaa tccttctttg ctttgcggcg tggcatctaa tggtcggatc
    40861 aattgataat tgcctccgtt tgtttctgta aatccattat cgcgcaatgt atatcttttt
    40921 gcatcaggat gcaaacgata gctaattggt gcgcccagta ccgttgctgt tgtttcaaat
    40981 gccatgattt tcacctcgat aaaattagtt tctctttatt ataaaagttt atcctgattt
    41041 ttactaggtt tttcagttaa gttccctaaa aaatgaaggc gttctctcag acatctgttc
    41101 atataagaat gacttcacta gttatttttt gacagcacga actaattgat caaggaaata
    41161 ctggatgtcg tcttcggtat ttcccaaacc aaagctgata cggatggatt cttttagtat
    41221 cggtgtatct tctccataca ttgcttctaa tacgtgtgaa ggctcgatat ttcctgctgt
    41281 acaagctgaa ccagtagaaa tagcgacccc attaagatca agcttcatca gtagcaaatc
    41341 atttgcttcg ccaattaagc gaagattcaa cacatgaggg agtttattcg ttaaatcacc
    41401 atttacttga taagggattt cgtttgcttc taatgtatca agaatcaatt gctggaatcc
    41461 tttatatttg ttgttacgtg cttcacgttc ttcaggtgac agcagttcaa ctgcttttgc
    41521 cataccccag atccctgcta aattttctgt acctgcacgc cgcttttctt cctgctcccc
    41581 gcctaaaagc aatgcaggga tatttactcc gtctcgttta tataagaaac cgacgccttt
    41641 tggcccattg attttatgag cagagatact taataaatcg attcctaatt cttctggatg
    41701 gatcgtttgg tttccgtacg cttgtaccgc atctgtatgg aaataagctg gatgatccgc
    41761 taaaagttca ccgatttctt tgattggcat caaatttccg atttcattgt tcccgtacat
    41821 cacagagacc aagatcgtat cttctcgtaa cgcttttttg acctcttcga tcgacagatt
    41881 ccctttttca tctacaggca gatatgtaac gtcaaacccc tttgtctcta aatatttcat
    41941 ggtattaaga acagcaggat gttcgatagc tgtagtgatt agatgtctgc cttctttttg
    42001 acgcgagaac gctgtttcta agatagctgt attatcccct tctgttcccc cactgttaaa
    42061 gatgatctcg tgaggttttg cttgcagact gtctgcaatg atttgtcttg ctgtttccaa
    42121 tttttcatgc gcgtggcgac caaatccatg tatgcttgaa ggatttccaa acgtgtcttg
    42181 catgattgcc gtcatcgctt caattacttg tggatgcatg ggggtagttg ccgcatgatc
    42241 cagataaata gttttcactt cattcatccc ttccaaatta ttgctaggca cattctagca
    42301 taaaatagcg aacaaaccaa agaagagctc atttttgtct agaggacgtt tcatgggcat
    42361 agaaaaaagg agctgtgaca aaagtcttgt cgcagctcct tgaagctgct cacttctgtc
    42421 acaacttctt tccctctttt ttttgtttat tcgaattctt tttcttccag acggaataac
    42481 ggactcatcg gtgtattttc atggatgcgt ttgaccgctt cacccattaa ttctgaacat
    42541 gtaacgattg ttaagttttc tggatgacga ttttcttctg tgaaaacaga atcagtgata
    42601 caaatatctt tgattggtgc attgtctaaa atacttttcg catgatcgga caataatcca
    42661 tgtgacgcac aggcatatac ttcttttgcg ccgttttctt ttaatacatt tgctgctcgt
    42721 gcaagcgttg ctcctgtgtt caagatatca tctaccatga tacatgtctt tccttgaaca
    42781 tcaccgatca cataaccacc ctcagttgaa gcatcatctg catgatctac gatggctaat
    42841 gtgctgttca aatattctga aagactacgt gcacgctgaa caccgctgtt ttttggcgaa
    42901 acaactacga tgtcatctcc cgtcagacct aattgacggt aataatgagc aaacaacggc
    42961 atcgtaaata aattatctac aggaatatca aagaatcctt gtacttgaac cgtgtgcaga
    43021 tctaaagtca gtactcgagt tgcccctgct tcttcgatca agttagcgat caatttcgca
    43081 gtgatcggtt catgaggttt cgccgtgcgg tcttgcctag catacccata gtaaggcaat
    43141 acgacattga tcgttttcgc acttgctcgc ttcattgcat cgatcatgat cagtagttcc
    43201 atatagtaat cattgacagg tgcattcgtt gattgaacga tatacacatg atcccctcga
    43261 atactttctt cgatattgat ggaaatctcg ccatcactaa attgcttcac gacgctttta
    43321 cctaattctg ttccgaacac tttcgcgatt ttttcagcta atggacggtt gccattcaaa
    43381 ctaaaaatct tcaacgtgtc atcctgatac ttattactca tgtagtcctc cccaaaactt
    43441 ctctattctt cgatagttta acatattttt ccaagatttt ctgttaattt cagcaaattc
    43501 ttaaggaagt gaaactgttc cgttactcca actggcagga atgactttat gataatcgcc
    43561 ccagttgtcg tgtactttgt aataacgttc tcctgtttca gtttcaaaat aagcgtacgc
    43621 tgtcacccaa tgattgccat atgtactgcc aagtactttc aaaataccaa tcatcacagg
    43681 tttgccttca cgtatacgtt ttgtagctcg ctgccatgaa cctagaagag ttgctcgtgc
    43741 acgctcatga ttgccattct tctttaaaaa actagaaatc cctgtactaa cctgaaaagg
    43801 aatcgtagga agtcctagtg gttggatctg gctacgcaat gccttcgtca aaaccaacga
    43861 atcagccgta tttttcttgc gaatctcatt tggaagcatc caccccttac gatagtcttg
    43921 ataataggca aggagaactg ctgccgcgta agtaccacaa agatagcctg agggggtagc
    43981 ccatttctta tacctcaaaa aacgttcttc tggcaatccc acccagcaat ttgcgagttc
    44041 ctttcctgac cttttttctt cgatcaaaac gggaatatct tcttttctgt tgatccatct
    44101 agataactcg attggctctt cattgatcag cttccatttt ttacaagaaa gaccctcttg
    44161 ataagtatat tttgctggag aatattctac cggatgtcct gattgatcga taatcacata
    44221 actttgatct tcaaaaacca gagctaaaaa aagcaattta ctttttcttg actgcagctg
    44281 ctgagtgctg gctaattttt taattttttt atctactttg aaatataaag gtttatccac
    44341 tacttgattc agttgggatc gcctcctttt tttcattata agtgaaggat tgaaaaaaac
    44401 aaatcagttt gattgttcga attttcaatt ttttatgttc tatttgttaa ttccttcatt
    44461 ttgtaagata atgggcacac gaaacaaaaa aggagcgatc gatgaatgaa caaagaacga
    44521 ttgaaacaag atttctatga agcagtcaat gaagaatggc aaaaaacagc aaaaatccct
    44581 gcagataaac cagctacagg cggtttccaa gatttagttg acgggatcga ccaacttttg
    44641 atgggagaaa cagacgatct gcttgcccat ccagaaaaag tgtcttcaga aaaaatgaaa
    44701 catttccttg catattatca actggcaaac gattatgacc gaagaaatga gttgcatgct
    44761 caaccgcttc aacctataat cgaaaaagtt gaatcattgc agtctttcga cgaattgaat
    44821 aagcaatttc cagaatggct gttggataca ttaccattgc catttaatct ggatgtagat
    44881 gcagatatga agaatgcgca aacgaacgcc ttctttgctt atccgccttc tttattcctt
    44941 ccagataaga cgtattatgc atcagaccat cccaacggtg cacaactaat aggcgttttc
    45001 tttgatatgg ctgttcagtt attagagctt gccggcaaag aaaaaagtca ggcagaagca
    45061 atcacggaac aagcagtgca atttgataaa ttgattgctc ctcatgtaaa aagtgcagaa
    45121 gaaaacgcag attacagcaa aatgtataat ccgcaatctt ttgatacatt tattaaatac
    45181 acagataaac tggacttgaa aaaacttgtc acgggtttga ttgggacaac tccagataaa
    45241 gtgatcgtaa ctgatccagt gtacttcgat catttgaatg acatcctgac agaagctcat
    45301 tttccgttat tcaaaagctg gatgatcatt aaaacagtac gttctcttag tggttatcta
    45361 tcagaagaat tccgccaagt cagcggaatc tattctcgcg tattgtctgg aacagacgaa
    45421 gcaatgcctc agaaaaaagc agcgtattac cttgcctctg gacaattcga tcaagtagtt
    45481 ggcgattact acggaaaaaa atattttggc gaagctgcta aaaaagacgt agaacaaatg
    45541 gtgaaaaaaa tgatcgccgt ttataaaaaa cgtctagaag aaaatgactg gcttggggat
    45601 gcaacaaaag aaaaagccgt cataaaatta aataacttag gtatccaagt aggctacccc
    45661 gataagatcc cagcattatt cgaccagttc aaaacagtac ctgcagatca gggtggtact
    45721 ttgctttcaa atactcttgt tttcagcaaa ctcacattaa aagatcgttt cagcaaatgg
    45781 aacaaaccag tggatcgttc agaatgggaa atgagtgctg acacggtcaa tgcttattat
    45841 catccatttc ggaatgtgat cgtctttccg gcagcgatcc ttcaagcacc attttacagt
    45901 ctagaacaat caagctctgc taattatggt ggaatcggag ctgttatcgc tcatgagatt
    45961 tcccatgcat ttgataataa cggcgcttta tttgacgaat atggcaactt gaacaactgg
    46021 tggacagaag aagatcttac acaatttcaa aacaaagcac aagcaatgat cgaagaattc
    46081 gatggtctgc cttttgctga cggaaaagta aacggaaaat taaccgtttc ggaaaatatt
    46141 gctgatgcag gcggtctaag ctgtgcattg gaagcagcaa aaacggaatc agatctttct
    46201 atcgaggaat tctttgtcaa ttgggcaacg atttggcgta caaaagcaaa aaaagaatac
    46261 caacaacttt tactgcaaat cgatgtccat gcccctgcta aactccgagc aaacgtgcaa
    46321 ccaaaaaacc ttgacgaatt ctatgaaaca tttggtatca cggaacaaga cgctatgtat
    46381 ctagcgccag aaaaaagagt gcgaatctgg taagaggttg tgccagaagt ggtcagcttc
    46441 aagaaataag aaggaatttg ggaaaatcgc ttctcaaatt tttgtgacat ttcggcttat
    46501 ttttcgaaga agttacttct ggaataccat gtattagagg ttgtgaaaaa gctgcttagt
    46561 ttcaagtagt aagaaaaatt ttgtgaaaat ggctttccac atttttgcat aaatttgact
    46621 tactaccgag aaactggctt ttgaacaccg tttatcgaga ggttgtgaaa tcagcgtcct
    46681 gacctgagta ttagagaaaa aaacggaaaa atagttcctc atattttgcc gtttgttgag
    46741 ctaataccga gggtcagctg attgaacacc gtttagtgga gagattgtga aaaagctgtc
    46801 ctgcatcaag taataagaac agccaatcaa aagcagcaag gagaacctca tctataaaaa
    46861 gatagaagga agtgagacat ctattggtct catttccttc tatttttact ttcctcagtc
    46921 aattgtttta catcataaaa ggagaaattc cacttatttt tttcgctgtt tcatgacata
    46981 aacaactaca ccgattaaca aaattcctcc agctaatgct agcaacgggt tattaaattc
    47041 tcccgttttt gggagtcctt gagtgccatt tttttcactt tcttttgctg tcctatccgg
    47101 atgagaaggt tttccatttg gttttccatt tggtgattca tttcctggat tttctctttc
    47161 tggtttgtca tttcccgggg gcacatcggc agtttctcgc acagtgatcg ctttttgctg
    47221 ggtaacagat tctgtatgag cagaccattt ttccccatca aatatttccg aacgataagt
    47281 gacttctagc gtatattctc cttttgaagg tgctgaaaaa atagcggtat gattagaaaa
    47341 ttgagcactt gactgtgttt caacgatttg gatcttttct gggaaataac gcatatcttc
    47401 aaagacaggc gttccttgat ttggtgtgaa agttgacaca aaaactgtaa aaggcttcag
    47461 ttcaatgata tttccttctg cattctccgc cacaccattt gcttcttgta taataatcgg
    47521 attattttgt tcatttggtt ttgtctgatt tggttcttgt acgattgcat actctggata
    47581 ttccgaagac ggtgaggttt ctccgtcaaa aatagcacct acagataatg gaagaccatc
    47641 cactctttcc ttttctgttt gacgattccc cggtttaatc tgcatcagtc catgaacatg
    47701 gatacttcca ttttcatagc gcgtaacagg ctgctgacct tctttcgaac atgtatttag
    47761 agactcgatc caatcttttg atatggtatg tccaagagta ttttctgatt gtttctctcg
    47821 ttcattccaa tagtagttca acgagtggta gatttgatct tcgttttgat tcaatgggcg
    47881 gatctgctct ctcatctcaa gattctctgt tcggaaagat aagataccag aagcatggta
    47941 gtctgtgttt cctgctgaag aggtataaag agccacatta tatgaaccgt tattaaaact
    48001 tgtactgcta ttgacgataa tatctgttcc gctattggaa tcgattcctt tcgcaagatt
    48061 ttcgaaagac aaactattga tcaattcatg agggcccgtt aaagaagaac cgcccatttt
    48121 gaatccatta ccgttacctt ctccctcaat tcctggtacc cagccgtttc gataagcaac
    48181 tgagtttttg atgattactt ttccgatcga acctgtttca tttttagcaa aaaggtccca
    48241 accgtcatct gcattatgat acgcgataca accgtcaaat acatttcctt ctcctattgt
    48301 cagtttggcc gcaaatccat cggcatcttc aaatcctgga tcggcatttt caaaagatgt
    48361 acagttcttg actaagttat gcgcgggcca tgcttcgaaa ggatcatttg agctaccgct
    48421 gatttggatt cctgtatttc cattccgata agcatgaatc tcttcgatca aattatgatt
    48481 tccagaaatc tgtaatcctt tttgcatagc tgcactattt gtaatgtcaa accctcgtaa
    48541 accccagtag tgactgaaca gtgtcatccc atttccagtt cctttaaaat caagtacagg
    48601 acgcttgttt tctggatttt tctctgcaat caactgaatc gggttttctc ttgtcccgtt
    48661 aacgcctttt ggaatcgtca atcctctttc gaaggaataa gttccaggcg ccatgacgat
    48721 tgtctgccca gcatatgcgt atctcaatgc ttgtgtcaga gataatggat tttgtctgct
    48781 tccgtttcct gcatctgacc cttctggtgt tacataaact gtcgaatatt taggtttacg
    48841 gtagtccact gtatgaagaa tctcttttgt ttcataacta gtcatctcta cgtattcttc
    48901 tggcggatag tttttatctg gcgtaaaact gaaagtaaat tcgttcgttc cttccatcag
    48961 ttttgtctga taatcaaatt cccgattcgc agtgatagcc aagttttttg cgttcttaag
    49021 cacctctcct gttgctttat ttttaattgt caataatccg tcagcatttg ctctaaagga
    49081 catagtatga tcttggtttc ctgaatgatt actagaggtc acagtgtaaa tcggatcaat
    49141 caagcgagta ggtctttctt gcccaggagg atctgtcgca ggatctgagt aagcaacttc
    49201 gattccttct accttgatcg tcatattcct tgctgcagca aatcctgcat aaataaccga
    49261 ttcatctgaa gcgtataatt tttcccagtc atacatgatg tcagaagcca tttcttctcc
    49321 tgtttcagga tcgtaataat atgcctctaa accagtattc gtttttttca tctctacgtc
    49381 cagtttagta atcgagttcg tggccggaaa cagattccca tgaccgtttc cgaatatatt
    49441 ataagaacct gtttcttttt ccaagaaccc tgctgaagtc tctaaaggtg ttgtttccac
    49501 tgagacactc ccaggagctg gcgcagcttg cggatcttca gatgatattc ctgtgattgc
    49561 ccgtgtcccc aatccaagtc gcatcgtata tttgctgccg ctcgtgttga ccacttcttg
    49621 tctatccgag tcccagacat attcgatccg actgcctagt atggcaaatg aatttgaata
    49681 aaatgcctgc ccaaacaaat gattttttgg tactgcgtct cttaccatta aagcaaatcc
    49741 ttcttgggca ttcgtatagg tccaagattc tatttcgatc gtcgcccgca tcctaaagtt
    49801 gatgtctttg gggattgctt gataataata ggtcattcca tctgatccgc ttgactggaa
    49861 ttttccgccg ttattcgtgg aagagagccg cacgccgtct tctaatggtt caatggcata
    49921 cctactagca cttgtgcttt ctccgaaaac aacccctttc cactcttcat ttgcttcttc
    49981 agattgcttt tttgtctttt cattttctga ttctttcatc ataggatcat ttccttcttc
    50041 cgtatccata tcttcactag ttcttggtat ttcctccatt gttgacatcc cttcaatgtt
    50101 cacgtgtgca ttttcttcgt tcacagactg ttgttcgtta gcagcaactt caacgacaga
    50161 aattaaaacc ggggtactga gcataaggag attcatcatt agcgcactgt attttatacg
    50221 tttttttaac aagtgtattc ctcccgtaac aaattagaaa gcgtttactt aaagtattac
    50281 ctaatttatt tttactgtca ataaaaaaca aaattataat aagtgtattt tataaaaaga
    50341 aaaaatataa cttaagttgt tgataataaa gagatttatt aacgtaaaaa gaataagttt
    50401 ttttaaaata acgtataaaa aagagcataa aacaaagtcg tttgttttat gctcttcttt
    50461 tattattttg tgctttttat tttatcaaat cactttgttt ttttataaaa tttctgcgcc
    50521 tagtgtggac tcaaaatgtc tcaatgccca ttcatgtcca acgggatcga aacttgccac
    50581 ggaatctttg aaaatatgga gtttgtatcc tagattatac gcatcgactg ctgtatgcaa
    50641 cacacagata tctgtacata cgccggtcaa ataaatatct gtgatctggc gttctcgcaa
    50701 acggatgtct agatctgttc cactaaaagc ggaataatgc cgtttgtcta tccaataaac
    50761 attttcctct tgctcatagt cttggtataa actttttaaa gagccgtaca attcccgtcc
    50821 acccgttcct atcacattat gcggaggaaa taagcggttc tccggatgaa aggaatcttt
    50881 tggatcatgc gcatcaatgg caaaaacgac aaaatccttt tgatcaataa acttctttgt
    50941 atgagcagtc agcttttttt caattacttg tcctgctgtc ccagtagtca gctttccatc
    51001 ctctgcaaca aaatcatatg tgtagtcaat cgagatcaat gcgttcatct tagtcctcct
    51061 tatacgagat gtttgacaaa ttcgatcacc atttctgctg atcgtttgcc tgcgtcttcg
    51121 ataaattcgt caaagctttg tgtcgccgag tgatctgctg tgtcgctcat tgcacgtacg
    51181 atcaaaaatg ggatattgaa ctgacgagct gtttgtccaa cagcggctcc ttccatttcg
    51241 caagctaatg cttcagggaa attcgttaag atttctttga ttttatctgg cgagtcgaca
    51301 aatgtatcac ctgtaacgat caatccttct tttgcgttca aattcgttgc ttttgctgct
    51361 ttaaccattt cactgcgcaa atatgtgctt gcttcataat atagaggcat tcctggtaat
    51421 tgtcctgggt tgtagccaaa tcctgttgca tctgcatcaa aataagctac tttgtctgat
    51481 ataacgatgt cacctacttg taagccttca ccgattccgc cagctgaacc tgtattgatc
    51541 accatgttca cgccgtattg ttggatcaac agacttgtgg taatagatgc taagactttt
    51601 cctataccgg aacgtacgac gatcacttcg tggttaccta atgaacctga aataaataaa
    51661 gcgcctgcgc gttcccatga taatggttcg cttaggttct ctctcaaaat ttttacttct
    51721 tcttccattg cgccgataat accgattttc atctttttaa ttccttcttt ctatataaat
    51781 gcgattgcta aaaaaaccac acataacatt aggataacaa taataagaga tttcatcaaa
    51841 aaagagttcc atttggtcgt cttttcccgt tcgctgatcc ttgttttcgt gattggttta
    51901 ttctttttgc tttctttacg ataaaagctg gcaatctttt tttcttcttg ctgataagct
    51961 gtttctgctt ttcgctgttt ttttaatgac tcgcttgctt gtgcttgttg tcgcttgcga
    52021 agttcgcttc gcgtaataag cggtcctttg gccataagcc gatccctcta ctttcctttg
    52081 gtcaatagtt cccagtattg aatcgcataa atcgtctttg catcacaaat caactgatct
    52141 ttcatcgctt gttgcgcctc ttcaagagtt agatgataca actccagtac ttcgtcttca
    52201 tcttgtgcta aaggattctc gaccttctct accccttgtg catgataaat atgaaggact
    52261 tcatttgcaa aacctggtga aagatacatc gaagtaagat ggctcagcga cttcgcacga
    52321 tagccagttt cttcttctaa ttctctagct gctgtcattt cgggattttg tccttctcct
    52381 ggatcgattt ttccagctgg aatctccaaa atcacttttt ctaaaggttt tcgaaattgt
    52441 ttgacaagaa gcagacgatc ttgttcgtca aaagcaatga tcccgacacc gccaggatga
    52501 aataccagtt ctctcttcga agttcctcca tctggcaaac gaacttcgtc tacagcaaca
    52561 tcaataattt ttccgctata gatttctttg cgactgattg ttttttcttc aaattgctca
    52621 ttgttcagca tatcttctcc tgctttcttt gtaatcataa ctgctttttt ttcatttttc
    52681 aatttttctc aaaaactcct tattagttta ccatagataa accttagatt ttctctaaat
    52741 atagaaaatc cttctttagt ccgatactct ttctagtagt ccgtatgcta aaataagtat
    52801 gtaatcgaat aacgaaaaga attcaatact caacgataaa tgacatggag ggtttattat
    52861 gataaaacga aattggccgt ggcttctagc attggtcttg ctatttctct ttgtccgaaa
    52921 caatagtttt tcttttgttc taggactttt attgataggt gtagttttag ttttgtgggg
    52981 actctttggt tcgcgcagga aaaagggaaa acaagaagaa attcctgcac tgactgacga
    53041 acttgaaact cactatgaaa aaagcggtat gacagcgaat gaaatttcat tttttcgaca
    53101 aacaatgaat caaacaaaaa atgagatcaa tcaattgcaa atgaatatgc agcagacagc
    53161 caaacttaaa gcaatcgatc tccgccatga tccagtcaaa gcagcgaaag ctttattcaa
    53221 agaattggtg aaagaaccaa accgactgca tgaagcaagt cagtttcttt atacgcatct
    53281 gccgaatcta gttgatttga caaataagta taatgagatc aatgaccatg agatcaaaaa
    53341 caaacagacc tatgaaaaac tagaagaaag cgcgcagatc atcgaccagc tgtcagcttt
    53401 aatcgcacaa gattatcaaa aattcgttgc tgaggatcta gatgatatcg acgtagagat
    53461 atctgttgcg aaacagagct taaagcgtga taataaatat gaaccagaac aaaaggatta
    53521 actcttttgt tcataaaaga agactcggaa cattcagatg atgtctggct gtttcgagta
    53581 ctttttctaa agtagagaca ttcatgtaag aatcgagaac agattcaaca aggaggaatt
    53641 ttttatggat cataaaccga ctgaaacaaa agatgttaca ccagttaacg atacacttga
    53701 agatttattg aacaacccgt tttcaactcc aacagatacg ctgaccactt cacaacaagc
    53761 ggagattgat cagctccaag agcaacagac agctgctcgt ttaattgaca aactaccggc
    53821 ggaacgccaa gaacaagcta aacagctagc agcaaaaatc gatgctaatg atgcacagtc
    53881 tgtcatcagc tacggatcgg ctgcccaagc aaaattaagt gaattctcac aatcgatgtt
    53941 gaatcatgtg caagcacaag atattggtcc tgtaggagat tccttaactg aactgatgta
    54001 tcgtctccaa gaagccaatc ctgacgaact gcgtgccgga gaagggaaca tcttccagcg
    54061 tgtcttcggg aaggtcaaac aatcgatcta tgaagtgaca gcaaaatatc aaaagattgg
    54121 tgcacaaatt gacaagattt cagtgaaatt agataaagaa aaagacggtc tgctaaaaga
    54181 taatctgatg ttagaacagc tttaccagaa aaacaaagac tactttgatg cactgaatat
    54241 ttatatcgct gctggagaat tgaaaatgga agaacttcaa acaacgatca ttccagaagc
    54301 gatgaaaaga gcagaagaaa ctggcgatca gatggatgtt cagattgcca atgattacac
    54361 gcaattccta gatcgtctgg ataaacgtac gcatgatctt cgcttagcta gacagatcac
    54421 gatccagcaa gcaccacaaa tccgtttgat ccaaaacaca aatcaggcct tggctgaaaa
    54481 gatccaagca tctatcgcta cagccattcc gctgtggaaa aaccaagtcg tgatcgcatt
    54541 gaccttgctt cgtcaaaaag atgcagtaac tgctcaacgc caagtctctg aaacaacaaa
    54601 cgacttattg aagaaaaatt cagaaatgct gaaaatctca gccatcgaaa cagcgaaaga
    54661 aaatgaacgt ggaatcgtgg atatcgagac ccttcaaacc actcaaaatg atttgatcga
    54721 aacaatccaa gagacattgc gtatccaaaa agaaggaaaa gaaaaacgtc gtcatgcaga
    54781 agtagagctt ggacacatgg aagaagatct gaaacaaaaa ctgttggatt taacccaata
    54841 gatcaccttt cgcttgttac taaaacaaac gcccaacaac agtttattac aactgttgat
    54901 gggcgttttt cttatctttc ttctaacttc tccattggag tctatttctc attcatcttg
    54961 ctgtgtccat agccatagcc aaaataaatg atcagtccaa taaccattac gataccgaac
    55021 acgatccatg tcacagtttg cagacgaagc atcaatacaa tacaagtcaa aatggagacg
    55081 attggcaata gcggaacgaa tggcactttg aattctccag cttttggttt gccaaacatt
    55141 tttctcaact tcagtaagcc tagactaaca agcatcaaat aggcgagcgc catgatattc
    55201 gttagttccg ctaatacatt caatgggaaa aatccggcaa agaatacagc tgccacacca
    55261 gcggcataag tcgctttttt cggtgtacga tgcttttgat cgatttctgt cataaactta
    55321 ggaagtaagc catccttgct gacagcaaac agtaaacgag caagtgaata catcatcgag
    55381 atcgttaccg tcagtagcgt taaaattgcc cctacagcga tcaccgcgcc cactgttcca
    55441 tgtcctacat acctcattgc aaaagccact gggtcattga ctcctagttc agtatacgga
    55501 acgattcctg tcaagatcag cgtcacgatg atgtaaagga cagtagcaat cagtatcgaa
    55561 ccaatgattc ctcttggcac atctttttgc gggtttttga cttcctcggc tgccattgca
    55621 acggcatcaa atcccaagaa agcaaaaaac acaagagctg caccatctag cacaccggaa
    55681 aaaccaaaag gcatgaatgg ctgccagtta tcaggtttaa cgaaaaatat tcctacaatg
    55741 ataaacaacg cgatgatacc aaatttgaca tataccatgg cattattcaa acgtaatgct
    55801 ttcttggctt caagcgacac gatgtaagtg acgaatatca ctacgagcac cgcaatcaag
    55861 tcaatgtatg taccattttc cggattgtac ccgccagtta atgcttgtgg aagttcggcc
    55921 cctaaacttt tcaaaaaacc ttgcatatag ccagaccatc cggaagcaac agaggaaacc
    55981 gctagtaaaa attccccgat caacaaccac cctgtcagcc aggcagcaaa ttcaccaaat
    56041 acaacataca gataggcata tggcccacca atcactggca ctcgcgaagc aaattctgcg
    56101 aaacttagtc cagacaaaat gacaacgatt gcagctaaga caaatgaaag tgacagtgct
    56161 ggaccagcat tttgattggc cgcaacccct gtcaccacaa atattcccgt accgatgatc
    56221 gcaccaattc caagcatgat caaatcagac gtttttagtt cttttttcat ctcactcgta
    56281 tgattgagat tgatctcttt cttacgaaac aaatccattg aagttcctcc ccattttagg
    56341 ttggaaaaca gcgattaaac tgttttcata taccctaaaa ggataccacc taaaatgact
    56401 aaaaggcaac caacaataac ataaatgagc tcttttttcg tttttctttc gccaaggatg
    56461 aaaatcccac ctaaagtaga gataatgatc cccatttgtg aaagtgagaa gccaacagct
    56521 aaaccaagtg atttgactgt tagaagcatg cagatgtttc ctaagcccca taataatcca
    56581 cagatcatgt ttttccacac aaactgatcg actttaactt tacggaaagc aaagaagctt
    56641 gcgcctaaga tcattccgat actttgaggt aagataattg acatcgcatc caaattcgcc
    56701 cagttgacga tgatggtata tacaccataa ccaatcgtag agaagatcaa tgctctaaaa
    56761 cccttaccaa aatcaagcat tttattatct gtatctattt ttccttcgtc atcttgtcgg
    56821 gcagtcaaat acgcaccgct tacaagaaga gctaaagcaa taataccgta tacataatct
    56881 ttcgtttgtg tccattcatg gaagaaaacg gctcccgcaa tcgtattcaa aattaattga
    56941 aaaccagtag acaatggtag ccctacagaa acacccatgt acttcattcc atggaactgt
    57001 ccattttgtc caacactcca agctaagccg gataaaaatc cgatcaagaa aatccaaggg
    57061 gtgattacag gactaacaac gaaaaagaca actaaagaaa acagaaatgc accgatcgtc
    57121 attcctagtg tttgttgatt ggcatcgcca ccaattttac cacttactaa accaatacta
    57181 ccccatgcca acatagggac taatgctatt aaaatttcca taaccaatct ccttttattt
    57241 cacatgataa gaaacttatc agcgaaaacg ttaacaacac aagcactttt tttcgtttct
    57301 aacgattttc taacgttttt cattataaaa atttaagatt gggaaaaata aagtcattgt
    57361 tgtccctttt ccttcagttg attcagccgt caaatggata cctaattttt cggccagatt
    57421 ttttgctaaa taaagtccta atcctgttga atgtgttttg ctaagtcgac catttctccc
    57481 agtaaatccc ttatcaaaga tccgtttcaa gtcttccgct gggataccga tccctgaatc
    57541 tttaactgaa aggctgactc cttgcgcttc cttttctatg ctcacaatga tgtttccgtg
    57601 atccggcgta tatttgatgg cattactaag caattggttg aagataaaag cgatccattt
    57661 agcatcggtc aaaacagtat gatcctcacc aacgatctcg tagcgaatat ttttttggat
    57721 aaaataattt gcctgactgc gtatcacagg ctgaatgatt ccttttagtc catattcttg
    57781 gatgaggtag tcccgcgaga aactgtcgag tcttgcataa tacaaaactt gttctacgta
    57841 ttcatcgatt tttgataatt cattttctag taatgtatac ttttgatcgt caatatcgaa
    57901 ctcgatcgaa cgaactagca atttagaagc ggaaagtggc actttgattt catggaccca
    57961 tgagtcaata taatcttttt ggtcttgttg attactgatt gctgattgca ttacttcttg
    58021 gtgttcacgg atcagctgat tgatatattc ttctaccagt ttttcttctt ctgtcctccc
    58081 accactcaaa taattttgca aaggggaagt tttttgtatg tcggctaatt ttccccacca
    58141 tcttctcttg ctcaagtaac cacccagcag ataaaaaatc agaaagacgc cctcaatcaa
    58201 agctaaataa gcaattgtgc tcaaatcaac tttgatgttt ggcgccagcc acatcacaaa
    58261 gatcgtcaat gcaataaaaa acagccatcc caagatcaat gtccactgat ctttcaaata
    58321 tttaaaaaaa ttcatcttaa ccgctcatcc tttcagggaa cgatatatcc ctgtcctact
    58381 tttgtttcga tatatccttg gatacctgcc tgttcgattt ttcggcgtaa ccgattgatg
    58441 ttgactgtca atgtattgtc atctacaaat cgttcgtcat cccacagtgc tcgcagcaat
    58501 ttttcccgac ttaagatctt tccattgtgc ttcatcaaaa taaataatag acgatattca
    58561 tttttgctca aatcaatgat ctctccgttg atttccatac ttccgttgtc aacattcaac
    58621 gtaatgccat tgtggctcat catttcacta gataattctg tgtagttgta agaacggcga
    58681 agtaatgcat tgatttttgc aatcagtaca tcgatttgga aatgttttgt cacaaaatca
    58741 tctgccccca tgttcatagc catgatcata tccatattcg tattcctgct ggagataaaa
    58801 atgatcggta ctttcgatac ttcacgtatt ttttgacacc aataatagcc atccaaaacg
    58861 ggaagattaa tatctagtaa tacaagctgt ggttcttctc tttcaaagtc tgagaacact
    58921 tgattgaaat cggtcgttcc aaaggtttca aattgccatt tctcaagttc ctccatgatc
    58981 aattgtcgaa tgatctcttc gtcttcgact accatgattt ttgccataaa aaatccctcc
    59041 atctttcttc ttgctactac aatatcaaag aagcccttgt gaaacaagtt ggcttacctg
    59101 gaaaatgtca ttttagcaaa cgttaaaaaa aactggaaat atgcgattta atcgcgtttg
    59161 tctcttccaa gcagcttaaa tttattatgt tattcttaat aattggtcta ttatctgtta
    59221 tttttctttc gttgtttttg tcttttaaat tttcgataac accaataacc gaaaagcgtt
    59281 agcactagca atatacctag aaggagtata agtaatcgat aaagatggta tttttttgtc
    59341 tgttctatct ttgaagagac ttcttctgta aagggaactc gtcttcctgt cactagtaat
    59401 cggtgagtgt tcacggtgta aggtgtacaa gtgataagtg tgactagatc ctgcttttct
    59461 ctaattgcta atgtatttgt ttttgttgga aggacaacaa ttttctcaac gacttcataa
    59521 gcgagcatcc gaccatacac ttcaagatag aatcggtcat cttgctccat ttcttcaaga
    59581 tccgtaaaga gttttttctc agcaataccg ctatgggcgg taatcacgga atgtgtactc
    59641 tctcctccag ttggaaaaga ggtgccttgc aggactgtcg ctcctctatc taacaaaaga
    59701 tcattcgttt catcaaataa aggcaagcta acattgattt tcggaatata gatggctccg
    59761 atcatatgtt gttcgtaata ttcttttcct ggattttgga catttctaac cgcttgctca
    59821 aaaggatctt tgacttgtcc cattcctggg attactgatg tatgagcaag cgtctgattt
    59881 ttcttttcat gcactgctaa ttgttgctca tgtttttctt ctttatcgcg ttcaagctgc
    59941 ttttgataat tctcgatcct tctttgatcc aaataattgc tgagagcatc tgctaaaaat
    60001 ggatatgtaa aaactgcagc tccggcaaga aacatcactg ccataaataa ttgtaataaa
    60061 agactgattt gggtttgagg tctattacct attttctttt tcattttctt caccttctta
    60121 tttaaaaaaa ctgcagcaac ctttataaaa ccgattgctg cagcttattt ttgttgctta
    60181 tacttcagac ttcattttag atttacggta ccagctgtac gctccaatca tcaaacttat
    60241 tccgattagt aagaatgcca agagcccgtt cccaccagta gcaggaagtg acccgcgttt
    60301 catattcggt actctttctg gccctggatt ttctactcct acgatctgaa tttcttcatt
    60361 atagcttcca taagagatga taaattcagt aaaggctgcc tcacctgttg gaagtacata
    60421 accttctggc gccatggtct ctttcatttg ataggttcca taatctaacc cttgaacctc
    60481 aaagtatcca tttccatctg cgacaaattc tgttgcttgt ccgcttgttg cccactcaat
    60541 tctatctgct cctgattcat aaacagctaa aggcgactcc cctttataaa atattgcgta
    60601 ttcagaacgg tcttcattcc acaattcgaa tcttgcatct ttaagcaatt cactgcttga
    60661 tgcatcatat ttttcaaact ttcttccacc tgttgtgact ttctctggcg gctctactcc
    60721 ttcttcataa tcaaattcat catttcgtcc gatttcaata accgctgtgt tgttatggaa
    60781 atcatccgct tctagttctg tggaaacctt caaattatac gtgatcgtta aatctcctcc
    60841 acgtgcatct gctaatctac ctaaagtatc tactttggct actccatttt cttctgtcaa
    60901 aatcgtcacg acaaacccgt tgcttactac ttctactata taatcttgtc cttttgttaa
    60961 aatcgtctcg ccggctcgca cttctatttc ctgatcataa taagttagac caactgtagg
    61021 cgtatctgtg attttgtaat ttttgataac agcgcttccg ttttcaagga cagaatcgat
    61081 gaaataagga ataggtgctg tgatcgtgta agaagccgtt tttcctcttt ctagatcaat
    61141 ataagaaatc gtttcttgtt ctccagcttc attaataatc gttacttgtc taaggtcgct
    61201 ttcctctaca ttcatctgtt tatctgcttc tctgatttcg tttttcggat acaaatgcac
    61261 atctgtattg tatgtgtctt tccatgtaga accatcccac acgccatcca ccatatcagg
    61321 catcatcact ggcatcataa caaccattgg agacgcgatt ctggaaatat gagctggcga
    61381 ataagtttct aagaaaagat agactttatc tctagaagaa ggtgcttctt ccgtcacttg
    61441 gacggtagag aataccgctt ctccagcttc attcgttgtt tgtttgtcaa tacttgtcag
    61501 tcgatatttt aaaaaccaac tttctgtgtg ccgtttttga atccattcaa tcgcttcggc
    61561 agaattaaga ccgtcttctc gttccggtgt taaaggatta tctcgaatca aatcgtaata
    61621 tacttccgtt acgtcaaaca aatcaaaatc gactcctgga atattttctt caccaaaatc
    61681 cgtagaaacc aatccgctat tcggtcgttc ttccggaaca gatgagaaac cttttttgtg
    61741 taatgtaatc gtcacttcac ttggtttttg tgcgacttct tcggctttga ctagttttcc
    61801 gttcccgaaa atccctattc ccgcagtaac gagtaacagt acactcattc ccgtgacaat
    61861 cattttttta ttcatttttt tctccccgtt ctttttttat taataaaaca gcacctaaca
    61921 ataaaagaat tcctagtaaa gaaatcaacg ttcttgcttc attcgtttgc gggaatacgg
    61981 accattttcc tgattgacct ggattgcttg gaccactcgg ctctttcggt ttgtccgttg
    62041 tttcttttac ggtctcgtta taaacacgtg gtgttgcgga ttcataggca gagactggaa
    62101 ctttcccgga ttctaattca gccatctcct gtccgttaac tactacatat tgtggttggc
    62161 cttttgcatc cacccaaaat tcagggatga tgacctcgat tctcttactt gcttcatcca
    62221 tctcgtaacc ttccacacct tttaattctt caaaataata ggtgccagaa ggcaagaaac
    62281 gttgtcctgt cgtaacaagg ccctctttat ccgaaatgaa tttgcttaca tttttgtcat
    62341 tcaaaggatc attgtctgct ggtttgatcc attgattttt caagtcatta gcaggagcca
    62401 tatctaaata atatttcccc ccttctatca tctgatatag agcaaaaaca gcaccttcta
    62461 atggttttcc tttttcagtt gttcctcttt gacgtccata cttgaagaag tatggatctc
    62521 ttagataacc gacattttta ggatagatat gaatctcttg cagttcctcg gttgattctg
    62581 tcgggtgata aattggcaaa atagcagcaa ttgggatagc tgtctgatcg atatcaacat
    62641 ccaatccaac ttctggatca atcgattctt cgaaaatcaa ataaactgca tcccgatctt
    62701 ggtttttctt aggtgctttg atacgtgcaa tcccgtctcc taatccgcca accgtatctt
    62761 tcccagttgt taccgaagtc cctatttgga caagcctttc ttctgtgatt agctgacgga
    62821 tattgtttct gttcgtttca gcgatttgct ggacgaattc tttaggagtc atgttttcag
    62881 cagctttttt ttcatgataa taatcggtca tgtcgtaaat ggcaaatgtc gctccattta
    62941 gtggcaccgt ctgtgaaatg atatctgctg tttcccctgc ttcctcagag atagccaagc
    63001 catcattttc atggtattca aattgatcgt tataatcgat atctcgaatc atccgtttat
    63061 gcaacacgaa ttccacgaca tcttcccctg attcttctgc cgacatcgca tgtggaagaa
    63121 ggactgctgc aagcggtagt aaaacaagta attgaagcat caaacacaac agctttttca
    63181 ttaccttgct ccctcctttt tagattgtct gacaaacaaa ccataggctg ctcctgcaag
    63241 cgccatgaag aatgcagcaa gcaggatata gaataatcgt ccggatcctc ctgtagcagg
    63301 caacggattt tcaggatcgt tcccgacact aagctgtaat ctgattcgat ttgtctccaa
    63361 aagttcatat tctaactctt gctgtagatc aggcgtctct gcttcttcgt ttggataata
    63421 cgaaatctca acttttagtg tacccgcttc ttttcctgga actacccgat cattttctat
    63481 gtcaggttct tctcgataac taatttctaa aataaagtaa cctggaagtt ttctatagct
    63541 gtcaggtgac ttcacttcct tgatccgata gaccccttcc aacaagtctg aagcattgaa
    63601 tagggaagaa tcgtttggat ctggtgccaa gcctccctcg atgatttcat actctcctgc
    63661 actattttgt ttctcaattg aaaattctgc gccttcaaga cgtcggctat tcatactgtc
    63721 aattttcaaa agttccaaat cgattggcgc tagttcatct tctaaggtta cttgtagtac
    63781 accatcgatg atttcatagc cttccggcaa gggagcagtt tcgtcttcga tgaccgtatc
    63841 ttcaatgata aacttacctt cttcattcag tgcaaactgg aacacttgat cagatagccg
    63901 atacccattt ggtgcgacag attccgagac ctcatattca ccaatagaca gatgcagagg
    63961 ttggtcgtaa tttaaatcga catacttttc tactcctacg gcacgagaat agaagtatcc
    64021 gatcccaggc aaacgtttcg attcttctgg ttctaacgga ttaccagtgt atgctcgata
    64081 cagcgggaag gaagaatccc ccactttcct gatatcgaaa cctgcaccat ctaatgtatg
    64141 gccttcatgg tctaattttc taactcggat ctcccgataa tcaaacgtat tgtaagcagt
    64201 gaatgctacc cataaacgat cctcttcatc tgttgtatac gtgagatatt gccaattttc
    64261 ttcacctgtt tgcttgagtt ggatagtccc tatagcatta tcgtaaagtc gcaagatcca
    64321 tgtgtcattt tcatcaggtt ctttgaaacc ttctgggttc tggctctcaa tgattttgta
    64381 ttctgcatag ttggtagttt cttcactatc cttataaaca aatgaatctg gctctccgat
    64441 tggatgaata actttctcac catccacgat tacatatttc ccgtcttcat ctactgaata
    64501 gaacgtgagt ctccctttct cttcctctac ttcgttcaca ccagaaagcc ctttcgctac
    64561 tggatatccg atttccagtc cgttaccatc tgtttcataa agttcaaact ctgcgccatt
    64621 gattggcata ttactgcctt caattagttt attgatattc atgtggattg gcttgaattc
    64681 atttcgcatt tccagtttga catacaactc atcatactct gtgccttcta tgttaggctc
    64741 ttgtacaaca gaaagcttgt gatattctcc ttcataatag gaattcggat ctttaccttc
    64801 cggtccgccg actctcgaac cagatgtata ttcatctaca agctcgtagt gacctaacat
    64861 ctcatcttcg ttggctgcat attttttgat ttggaattga tacgtctcat ctactaactg
    64921 ataacgtggt ggtccagcga tctctctgat ccaaaatatg tcgctgactg ctccagtttc
    64981 atctcctaaa atcggcatct tcgtttcaaa gatcgctatt ccgtccgtgg tagttttact
    65041 tgtttcgatt ggttcggctt ccccactctc tggattttgg tcatataatg caaattcgac
    65101 tccagccaac ggctcgccat tttgaccctt cttgctgact tggaaattac ggcctttatg
    65161 ttcgtaacga atggaagaag atgggaaata catccgtcca gtagtgatat cattctcata
    65221 atcctccagg ttctgaatat aggccatatt gttcactgtg caaaaatttc cgtcttgagc
    65281 tcccgcatca agttttactt ggtacttgat cctgaccatt tccccttcac ctaaagaaat
    65341 cggagaaaat ttataagctt ggttttcccg tccgacatac gttgtcggag tcgccactac
    65401 ttctggtggg gcttgtccat gacgttcttc atcccatatt tctggctctt ggtacttcat
    65461 gccgttttct cctggatcta gatggtaaaa ctgaatatct gccgatctgc cagctccaaa
    65521 tggtgagaca ttaaaaccag tttcatcata aagtgtggct tgctggatcg ttctcttgaa
    65581 ggtagaagag atatcctcca aggctgtaac aatgtcattc ttgttgttcg cattgtaata
    65641 tcgcggtgtt acgccatctt cttctaaatc agcaatattt ttcaatacat ttcgtccaat
    65701 agcatctagt cgttgtctcc cgctaacgtt tccatcgatt cctaaaccaa tggagaagat
    65761 acttggcggg ttctcttgat acttgttttt cagccaatga tgataagcaa ctgtgttgat
    65821 cgcagatgac ttttcttgcg aagtaggact gccattcgta ttgttattag aagaaccatc
    65881 accaacccag tgagtcgctt tattatctcc ttcttttacc tctccataac gatagtgtac
    65941 atttacttca tcttctggac ggttaaagtc agatgcatag gtaactggat gagtaaaccc
    66001 tgcattagaa gtattcccag aaaactcctc aaaatttctg aacaaaacgt cattatcttc
    66061 agcaatctta tcttccatca cagtccagtt gctccaagct ccattagtgc tcgtacgata
    66121 acttgactga atcggtgcat aactgaaggt cggtgtccca tctcccacaa cgattaggat
    66181 tttttctgga tttctatttt ctccgccatt gtctttatac aatgtttcat agccattttt
    66241 aagccctagt gtaagcggag ttcctccgat tggtgtacga tttaatgctg tattctcact
    66301 tcccgtcaaa cgattgatat catttgtcaa tggaaagatg tccgaactga tttgctcatg
    66361 gttattgata gctgtactat tatggtaaaa attcaccata ccgattcgaa tatccagact
    66421 cgggtcagag agcagatctt tactcatttc gtttactgcc tcaatcaacg cagcattttt
    66481 agtttgacta ttggtcccag cggttaattc actcatactc gctgacttat ctagaacaaa
    66541 aacgatatcg attggactga tttccttttt ctcgcccccg atgacatcta gatagacatt
    66601 gtaaagggtt gttgcatctt caggatgtag atcagatgct gtgctgcttg gcagaacagg
    66661 ttctacccat tttttgatgt acgccccgtt ataatccaag taactgtttt caaaattccg
    66721 ttcatttccc caaagctgaa cggtttgagc tggaacgttt ctatcttctt cgcctgcagt
    66781 tgatccatta ttagtagcat agtcgtaatt tcgccagttc gctcccccgt ttgtataatc
    66841 actatcatcg atcaagttct ctccgtcata tggcgagcct ttgtctcctt gatagcgttc
    66901 attgctttgt gtccaatttc ctaacacttt tgtatagtca ttcgttgtaa acttcgggta
    66961 gcgatgctgt tcgttttcaa cttctccgct aggatagata tattcatagg ggtcttgcgt
    67021 agctgttggc ccaagacgct ccaaaatacc gttgaataac tggcgttgaa tgcgctggag
    67081 tgcttgaccg ctgggtacga ttggttcgtc cagcttttcc atctcatttt cttcgctacg
    67141 ttgaatttca gcggaatctt ctgtatcagt ttcattttct tgtaattctt ggttatctat
    67201 tctttcatca accaccactt gaagaggtag ttacccttcg ttcacatcgg ggatcttttc
    67261 tgtttcaaaa atcaatgtgc cggtttctgc ttcttttgaa taaacttttc cgacatacca
    67321 ttcttgacca tcgatcgtct cgacttttag gtcttctcca tcttcatcat aggaggatag
    67381 acctgttcca cgaacgtttt ttacggtacc aatcccggcg gctgccgcat cgattgctaa
    67441 acgtattcta ccttcattgg cactttcctt tttttcaaaa gccagatgcc attcaagggt
    67501 ttcttctttt tcaatatact tcccttcaat ttttgcatag tcctcatcta agaatacctc
    67561 atcctccttt gtttctgttg actcagcagc tacatccagg gtcgtcatat gatagactga
    67621 ctggaaatat ggtccaaata gcaaactgac agttactaac tgcaaaagct tcaattttaa
    67681 ccctttcaca tccttatact cctttcaaaa atatttgtct tctttcacaa caatcaacaa
    67741 aacaatgccc atctaattat aatttaattt aattttaatt ttaaatcaaa tgatatcctt
    67801 tttagttaaa aaacaccaat tatacaacat ttattattaa aattaaatta taaaatttta
    67861 taacgttctc atttaacaaa acttaagtta ttaagacaaa tgaataaaca actacgcttt
    67921 cctcgaaaca aaaaaataaa gcacaaatgc gcatttacgc actcatgctt tattcgtaca
    67981 attaattcag ataacggcag cgcataggat gccaataaca cttcctaaaa tagctcctcc
    68041 taaaatgtca gtaggataat gtaaaagtaa aaaaatcctc gaataagcga tcaaacaagc
    68101 aaataaaaag gctaatattc ctgcaactgg acttaattcg aacaacgcag ctactgataa
    68161 aaaggctagc gctgtatgtc ctgaaggaaa agaagaagtc ttcggtttac ttgtgtaaag
    68221 gacaagccga cgattttttt cataaggtct tttccgtctt gtcgtttttt tgataaaaag
    68281 caaaccaaca aaaaaataga tcaaactgcc gataagaatg gctagaccat attctctagt
    68341 atcaggtatc aagactaaaa cagcagcaag gagcaaccaa ataaaaccac cattagagat
    68401 attactgata aatttcaaaa aattgatttt tcgactatcc gttttccgtt gcttggcgaa
    68461 cttgttgata atactatcat cgattttagc aatcaaacgc aacatgttat tcctcctttt
    68521 taagaacctt ttcttgcgta cgatggataa aaagcaggac ttgaaaataa aacaagaaac
    68581 tgaaacctaa taaagcaaaa tagattggtc ctgcaaacca gaatgcgaca agaaggatca
    68641 acgtgcctgc caaatagaaa agcgcgcttt tgaaatcatt aaaaaacaag aaaaatgcag
    68701 taatccaaga agcttctttt tgttccagtt gaagcaagat tttgtaacta aagagaagcg
    68761 cgcttaatag aagcaaaaac aacgtagtat acatcaatgt atagccaatt cccccacccc
    68821 aatagcggaa aatctgataa tcgatcaata gaagaagaaa ataaacactt gctaaactat
    68881 cttgctttcc ataaagagag aagttctcac gaaacttttt ccagaatagt gaaccgagct
    68941 ttttctcttc attttttttg taatgataaa tcatatacag aactgttcga cttgcagttc
    69001 ctaatgtgaa aacaggcaag acgcacagga accatagtag ctgtaaatgg ataagacgtg
    69061 gaatccattc aatgatttct aagaaataat cattggcttt tttaccaatc gatcgattca
    69121 tcatcctttt gaacctcctg tcaaatccat cccttcaatg aaataacgtt gtgcaaaaaa
    69181 gaacagcaaa atcgtcggga tcaagacaag tgttgctcct gccatcagat aattccattg
    69241 tgtcgttgct tggttctgaa aaacttgcaa gccaatctgt aacgtgtatt tttcttgatc
    69301 ttggatatat aacagaggac ctaagaaatc attccaagct gcgttgaagg aattgatcgc
    69361 aatggtaatc aaggcaggtt tcgtcaatgg aagcatcaaa tgactccaaa tatacaaatg
    69421 attcgctccg tcgatttcag cagcttcgat caattcatta ttgatcgata agtaaaattg
    69481 acgcatcaga aatatattga acgcattgcc gaagaacgat ggaacgatca ggggcaaata
    69541 agtacctacc cagccgatct tggagaataa tacatattga gggatcatcg ttacaaaccc
    69601 cgggatcatc atcgtagaaa gaaccaaagc aaacatcagc tttttcccag gaaaatcaag
    69661 cttcgcaaat ccataagcaa taaaagaatt tgaaaggaca ttaccgatca ctactagcac
    69721 agtgatgaat aatgtatttc ttgcatagcg ccaaaaagga aaggcggcaa tcgtatccag
    69781 atagttttcc catacgattt tttctgggaa aaaggtcgga ggataacgaa cgatttcttc
    69841 cattggtttc aatgaagtaa acaccatcca aagcaatgga atgatcaaaa tgattcctat
    69901 tactgtcatg aggacataac ttagtatttt ttttgtttgc cgattcacac tggtcttttt
    69961 gaaataatcc atcatttgcc gtcacctcca gaataataga cccacttagg tgcaagcttc
    70021 aaattgacaa acgtcagaac caacacgatc agaaacagga tcattgacat agccatcgca
    70081 taacccatat caaaagctac gaacgccttg ttccacatat gcagattata aaaaagcaaa
    70141 gaatttgcag gtccgcctgt tccatttttc gtcatgacat aagcttcttg aaaaatttgg
    70201 aaagaaccga tcgtagaggt gatcacatcg taaaaaataa taggagtgat taatggcaaa
    70261 gtaatacttt tgaactttcc ccaaacgcct gctccatcga tttctgctga ttcatataaa
    70321 gatctaggaa cattttgtaa tgtagctaag taaagtagca ttgctcctcc agaactccat
    70381 attttcatca aaatcaacgc aggtttcgtc cattgtggat caaacagcca agctggtcca
    70441 gggatatgga accagcccag aaatgtgttg atcaatcctg cagatggaga aagcagctgc
    70501 atccataaga tgtagactgc tactcctgat aagactgccg gtaaatagaa agctgtacgg
    70561 aatacactga ttcctttgat tttttgattg agtactgtgg ctaaaaacac actgaaaatc
    70621 gtcgtcagcg gtacattgaa gatgacgaaa taaacggtgt tgtataacga tttccaaaat
    70681 aaatcatcgt gaacgaacat tcttttgaaa tttgctagac caatgaaatt catcttggat
    70741 gtcaaattat aatcggtgaa actaccaata actgaaaaaa gcataggccc tagcataaat
    70801 accaagaacc cgataataaa aggcgagata aataaatagg cccatcttgc ttcttttttc
    70861 tttcggatag ataaacgctt caaattttct tgcctcctct gtacctagac agtcaaaaat
    70921 ggattattga ttttgcttga ctaagttttc tactgctttt tgtgcatctg ccaatccttc
    70981 ttttggtgat tttgttccta aaagaatctg gtcaatctgt tcattcacta atgtcgtgta
    71041 atccggagca tctaaaggaa ctggtgtgat caccgtattt ttaaagtttt cgtccgccat
    71101 ttgatagatc atttttcctt tatccgttag gttgtcatta ttcactaaat tctcattggc
    71161 tgtcttgctc gccatgatat caaaactttt ttcgccgaat ttttcttgta cttctggaga
    71221 agaaagatat ttgatgaatt cataagaggc ctcaggatct tttgctccgt atggtacttc
    71281 caagacgaat ccgccacccc acgaccaatg gcctgaacct tcttcttttt ctgggagctg
    71341 catcacgcca aaatcaaaat catccggtgc attttccatc aaactagagt aataattgat
    71401 attttgggca cgcatggcta ctaatccgga aataaatgga tcagatacac cagacccaaa
    71461 ttcggcttct aatttattga tcgtattttt cccataataa tcttgccagt cttggatcca
    71521 ctccaaggct tccactttat ttttagtatc aatcttgact ttttcatctt tgtcaaacca
    71581 actagtcccg ttatctgcgt ttagcgccca tacatcagcc cctaaattcc ataatggata
    71641 aaaaccgatg cgtgtaaatt cttttccttc ttttttatct agtttacgtg ctgtttcttc
    71701 taattcatcc caagttgtcg gtagatcttg ttcactgatt ccagcttctt taaataactt
    71761 tttattataa aaaatgactt gtgtatctgt attgaatggg atcgcataag gatcaccttc
    71821 atattctact gtatcccaaa gctgcggata aaaatcctta gaagtgtctt tttctacata
    71881 tttggagaga ttagttgctt gctgtgcttc tgctctttgg gcaacggaat ttatgtcctg
    71941 tacaataaca tcgggtgcat ttccagctgt tattgcagat aaagatttag tccagatgtc
    72001 accccatggc tgatacttat aatttacatg gatctcgttt tgtgattgat tgaaatcctc
    72061 aatgatttct tcgatagctt cttttcgtgc accggatccc caaaaggacc agaaatcaat
    72121 attttttctt ccatcacttg ttttttcaga agaatttgct gcacttgaac tggcatcgct
    72181 tgcattactt gatccgcatc ctcctaataa aaacaatgct gaacttgcca gcaaccctgt
    72241 aaacaataat tttttcatat tttacctcca aattttaatg taaccgatgc cggttttaat
    72301 ataacgatat cattttgttc tgaaaataac aatttataag gtatgattct aaaaaaatta
    72361 ttaatgatac caatacttta tataattcgc gagcgctttc tttgaatttt ttaatctttc
    72421 gtagcagaat gagaatgtat taaaaataga ttaggaggaa ttttgatgtt tagacaccag
    72481 aaagaattgc agtttgaagc aaaaccagat cgtccgaatc cattaatcgc gaaatatctg
    72541 caggagctga tcggcggcca atatggcgag atgagtgtag ctatgcagta cctgttccaa
    72601 ggctggagct gccgaggaga agaaaaatat aaagatatgc tgatggacat tgcaacagaa
    72661 gaaatcggcc acgtggaaat gttggcgaca atggttgctc gtttattaga gggtgcgcct
    72721 gttgaagatc aagaagcagc gatgcaaaaa gatccaacaa tcggtgccat tatctctgga
    72781 atgaatccac agcacgcgat cgtagctggc ttaggacctc gtcctgctga cagcgtgggc
    72841 aatccatgga gcggtgccta tatcattgcg agtggcaact tgttagcaga ctttagagct
    72901 aatttaaatg ccgaatcaca aggaagactt caagtagcac gtatttacga aatgatcgat
    72961 gatcgtggcg taaaagatat gctgtctgtt ctccttgcaa gagatagcta tcatcaaaat
    73021 ctatgggaat gtgcagtgaa agaattagaa gaaaaagaag gttcaatctt agtcccaagt
    73081 actttcccgc gtgacaaaga acgaaaagac attgcttatg acttctataa cttctcagag
    73141 ggagaccaaa gtagtgaagg ttcttgggct agtggcaaag cactggatgg cgaaggcgaa
    73201 tatcaatggt tgaaagaacc taagatcgaa ggcgctgcac caaaattaga accagtaaca
    73261 ccaaaaatgt atgggacacc tccattcaag aaataaatat ctacccgtag aaacacccgt
    73321 tttttgttcc acacgctttg tgagcaaaac tgactaaagt cattaatcat aaccaccctt
    73381 caaaagggtg gttttctcta gagctataag ctcaaatcac cggccagcgc ctaaagacgc
    73441 tggctttcat attttatgtt caagccatat tgcctttgcc agttttgccc acctcttaaa
    73501 aggtttatgt actactcctt agcccttaaa aggatcgtct tactctcgta cactcagctt
    73561 atctaacgca ctatcatgtt tttcttgttc ttgaatgtac tttttgatgg tcgcttcatt
    73621 ttgtcctact tttgtcacat agtatccttc cacccaaaag tgtcgatacc caaatttata
    73681 ttttagattt gcacaatctc ttgatgatct cctgaatatt ggctcgatat tgattataaa
    73741 ttatttttct tctatacttt ggtgtgaata caatgtggta tttacacatc tactttgtac
    73801 gggctaaact atttcccttt attgctccac ccgcatagca agtggttttg tatttcaatc
    73861 gctcggcgcg ctcaattagg tctaaagaca ataaatctaa aaacccgctg cttcactgac
    73921 agaaacaacg ggttttcaga aaaaaatgaa atgaaaaaga tctcttacgg caatctattt
    73981 tatttttttg attttttata aatggaaaat gcttcaagaa gtccaagaaa taaagccgta
    74041 taaaaacaag aacctatgaa atctttattt attagatatt caacagaaat cccgataaca
    74101 ctagccaaca atatatttat cagaagtgta aaataaggat gctttttata gaatagaact
    74161 agtgttgttt tcatagactc tcctttcttc atatttccaa ttaatcacaa attcacggca
    74221 ttactagaaa aattaaaggg gcgcagaagt ggaaaaatac tcttcgactt tccctacaaa
    74281 ccaggccatc ttgtgtttaa taactatacc aaatctaagg tacctctaaa tctaaattcc
    74341 atttgtggcg gtgacctcca atttttaact cttctatctc ccatccagta tacataacct
    74401 tgatacttcg accacttata tatcgaacac acaaatacct atccattgca ggagtactac
    74461 ctaacttagt tgctacttgc atctaaataa cagctgaaaa gataggactt actcttagta
    74521 aagtatctga actattaatt tttaaactat catttttatc ctcaactaca tgcacatctg
    74581 ttgcaacttc actttctgtc tcatccagat aaatgattaa ggaatcggga attgcaatat
    74641 cttcagctga cgctggaata gttgagctaa attagtcatc atatctttat tataaaataa
    74701 ccaacagcaa aaaatacaat gaaaaacaaa cttggaacta atgtatcatt aataaatgtt
    74761 gaaaaattca gcaactcatt actgtatgat tttagcagcc caaccaacat ataccctata
    74821 aaagctaata agatggttag gaatccttta gaatttttac tcattcatag acacttcct
//
LOCUS       DACBYO010000003        68626 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.003, whole genome shotgun sequence.
ACCESSION   DACBYO010000003 DACBYO010000000
VERSION     DACBYO010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68626
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.003"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(132..509)
                     /locus_tag="IVD26_000144"
     CDS             complement(132..509)
                     /locus_tag="IVD26_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078156.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            765..1493
                     /locus_tag="IVD26_000145"
     CDS             765..1493
                     /locus_tag="IVD26_000145"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAP6078157.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1493..1747
                     /gene="purS"
                     /locus_tag="IVD26_000146"
     CDS             1493..1747
                     /gene="purS"
                     /locus_tag="IVD26_000146"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAP6078158.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1749..2420
                     /gene="purQ"
                     /locus_tag="IVD26_000147"
     CDS             1749..2420
                     /gene="purQ"
                     /locus_tag="IVD26_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAP6078159.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2421..4643
                     /gene="purL"
                     /locus_tag="IVD26_000148"
     CDS             2421..4643
                     /gene="purL"
                     /locus_tag="IVD26_000148"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAP6078160.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4628..6067
                     /locus_tag="IVD26_000149"
     CDS             4628..6067
                     /locus_tag="IVD26_000149"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAP6078161.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6099..7142
                     /locus_tag="IVD26_000150"
     CDS             6099..7142
                     /locus_tag="IVD26_000150"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAP6078162.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            7139..7717
                     /gene="purN"
                     /locus_tag="IVD26_000151"
     CDS             7139..7717
                     /gene="purN"
                     /locus_tag="IVD26_000151"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAP6078163.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7714..9249
                     /gene="purH"
                     /locus_tag="IVD26_000152"
     CDS             7714..9249
                     /gene="purH"
                     /locus_tag="IVD26_000152"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAP6078164.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9265..10539
                     /gene="purD"
                     /locus_tag="IVD26_000153"
     CDS             9265..10539
                     /gene="purD"
                     /locus_tag="IVD26_000153"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAP6078165.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10661..11575
                     /locus_tag="IVD26_000154"
     CDS             10661..11575
                     /locus_tag="IVD26_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAP6078166.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11708..13273)
                     /locus_tag="IVD26_000155"
     CDS             complement(11708..13273)
                     /locus_tag="IVD26_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP6078167.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13266..14717)
                     /locus_tag="IVD26_000156"
     CDS             complement(13266..14717)
                     /locus_tag="IVD26_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6078168.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14731..15747)
                     /locus_tag="IVD26_000157"
     CDS             complement(14731..15747)
                     /locus_tag="IVD26_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6078169.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15967..17055
                     /locus_tag="IVD26_000158"
     CDS             15967..17055
                     /locus_tag="IVD26_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP6078170.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17109..18635
                     /locus_tag="IVD26_000159"
     CDS             17109..18635
                     /locus_tag="IVD26_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAP6078171.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18637..19842
                     /locus_tag="IVD26_000160"
     CDS             18637..19842
                     /locus_tag="IVD26_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6078172.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20099..21076
                     /gene="guaC"
                     /locus_tag="IVD26_000161"
     CDS             20099..21076
                     /gene="guaC"
                     /locus_tag="IVD26_000161"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAP6078173.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21340..22764
                     /locus_tag="IVD26_000162"
     CDS             21340..22764
                     /locus_tag="IVD26_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP6078174.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23225..24334
                     /gene="pdhA"
                     /locus_tag="IVD26_000163"
     CDS             23225..24334
                     /gene="pdhA"
                     /locus_tag="IVD26_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAP6078175.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24337..25314
                     /locus_tag="IVD26_000164"
     CDS             24337..25314
                     /locus_tag="IVD26_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAP6078176.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25339..26982
                     /locus_tag="IVD26_000165"
     CDS             25339..26982
                     /locus_tag="IVD26_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HAP6078177.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26990..28396
                     /gene="lpdA"
                     /locus_tag="IVD26_000166"
     CDS             26990..28396
                     /gene="lpdA"
                     /locus_tag="IVD26_000166"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAP6078178.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28558..28833
                     /locus_tag="IVD26_000167"
     CDS             28558..28833
                     /locus_tag="IVD26_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAP6078179.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28839..29606
                     /locus_tag="IVD26_000168"
     CDS             28839..29606
                     /locus_tag="IVD26_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAP6078180.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29774..31603
                     /gene="typA"
                     /locus_tag="IVD26_000169"
     CDS             29774..31603
                     /gene="typA"
                     /locus_tag="IVD26_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAP6078181.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31864..33636
                     /gene="recQ"
                     /locus_tag="IVD26_000170"
     CDS             31864..33636
                     /gene="recQ"
                     /locus_tag="IVD26_000170"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAP6078182.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33750..34052
                     /locus_tag="IVD26_000171"
     CDS             33750..34052
                     /locus_tag="IVD26_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAP6078183.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34055..35218
                     /locus_tag="IVD26_000172"
     CDS             34055..35218
                     /locus_tag="IVD26_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP6078184.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35244..38672
                     /locus_tag="IVD26_000173"
     CDS             35244..38672
                     /locus_tag="IVD26_000173"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAP6078185.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38693..39817
                     /locus_tag="IVD26_000174"
     CDS             38693..39817
                     /locus_tag="IVD26_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078186.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39807..40244
                     /locus_tag="IVD26_000175"
     CDS             39807..40244
                     /locus_tag="IVD26_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAP6078187.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40228..40566
                     /locus_tag="IVD26_000176"
     CDS             40228..40566
                     /locus_tag="IVD26_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAP6078188.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40685..41245
                     /gene="rsmD"
                     /locus_tag="IVD26_000177"
     CDS             40685..41245
                     /gene="rsmD"
                     /locus_tag="IVD26_000177"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAP6078189.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41242..41733
                     /gene="coaD"
                     /locus_tag="IVD26_000178"
     CDS             41242..41733
                     /gene="coaD"
                     /locus_tag="IVD26_000178"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAP6078190.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41723..42766
                     /locus_tag="IVD26_000179"
     CDS             41723..42766
                     /locus_tag="IVD26_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAP6078191.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            42925..43653
                     /locus_tag="IVD26_000180"
     CDS             42925..43653
                     /locus_tag="IVD26_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAP6078192.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            43769..44014
                     /locus_tag="IVD26_000181"
     CDS             43769..44014
                     /locus_tag="IVD26_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP6078193.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            44011..44229
                     /locus_tag="IVD26_000182"
     CDS             44011..44229
                     /locus_tag="IVD26_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAP6078194.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            44365..44904
                     /locus_tag="IVD26_000183"
     CDS             44365..44904
                     /locus_tag="IVD26_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAP6078195.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            44897..47170
                     /locus_tag="IVD26_000184"
     CDS             44897..47170
                     /locus_tag="IVD26_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAP6078196.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            47208..48254
                     /gene="holA"
                     /locus_tag="IVD26_000185"
     CDS             47208..48254
                     /gene="holA"
                     /locus_tag="IVD26_000185"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAP6078197.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(48343..48597)
                     /locus_tag="IVD26_000186"
     CDS             complement(48343..48597)
                     /locus_tag="IVD26_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAP6078198.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(48997..49266)
                     /locus_tag="IVD26_000187"
     CDS             complement(48997..49266)
                     /locus_tag="IVD26_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078199.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(49736..50191)
                     /locus_tag="IVD26_000188"
     CDS             complement(49736..50191)
                     /locus_tag="IVD26_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAP6078200.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(50329..52257)
                     /locus_tag="IVD26_000189"
     CDS             complement(50329..52257)
                     /locus_tag="IVD26_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP6078201.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(52454..53287)
                     /locus_tag="IVD26_000190"
     CDS             complement(52454..53287)
                     /locus_tag="IVD26_000190"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAP6078202.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(53479..54183)
                     /locus_tag="IVD26_000191"
     CDS             complement(53479..54183)
                     /locus_tag="IVD26_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP6078203.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(54206..54832)
                     /locus_tag="IVD26_000192"
     CDS             complement(54206..54832)
                     /locus_tag="IVD26_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP6078204.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            55158..57533
                     /locus_tag="IVD26_000193"
     CDS             55158..57533
                     /locus_tag="IVD26_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAP6078205.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(57557..58048)
                     /locus_tag="IVD26_000194"
     CDS             complement(57557..58048)
                     /locus_tag="IVD26_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAP6078206.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            58235..59155
                     /locus_tag="IVD26_000195"
     CDS             58235..59155
                     /locus_tag="IVD26_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP6078207.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            59309..59653
                     /locus_tag="IVD26_000196"
     CDS             59309..59653
                     /locus_tag="IVD26_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAP6078208.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(59843..60343)
                     /locus_tag="IVD26_000197"
     CDS             complement(59843..60343)
                     /locus_tag="IVD26_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6078209.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            60871..60954
                     /locus_tag="IVD26_000198"
     tRNA            60871..60954
                     /locus_tag="IVD26_000198"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60905..60907,aa:Leu,seq:cag)
     gene            complement(61278..61916)
                     /locus_tag="IVD26_000199"
     CDS             complement(61278..61916)
                     /locus_tag="IVD26_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP6078210.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            62251..62685
                     /locus_tag="IVD26_000200"
     CDS             62251..62685
                     /locus_tag="IVD26_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP6078211.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            62708..63028
                     /locus_tag="IVD26_000201"
     CDS             62708..63028
                     /locus_tag="IVD26_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078212.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            63169..63360
                     /locus_tag="IVD26_000202"
     CDS             63169..63360
                     /locus_tag="IVD26_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078213.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(63431..63688)
                     /locus_tag="IVD26_000203"
     CDS             complement(63431..63688)
                     /locus_tag="IVD26_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAP6078214.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            63846..64109
                     /locus_tag="IVD26_000204"
     CDS             63846..64109
                     /locus_tag="IVD26_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078215.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            64133..64321
                     /locus_tag="IVD26_000205"
     CDS             64133..64321
                     /locus_tag="IVD26_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078216.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(64404..64589)
                     /locus_tag="IVD26_000206"
     CDS             complement(64404..64589)
                     /locus_tag="IVD26_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078217.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            64804..65175
                     /locus_tag="IVD26_000207"
     CDS             64804..65175
                     /locus_tag="IVD26_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP6078218.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(65325..65397)
                     /locus_tag="IVD26_000208"
     tRNA            complement(65325..65397)
                     /locus_tag="IVD26_000208"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(65362..65364),aa:Gln,seq:ctg)
     gene            complement(65443..65871)
                     /locus_tag="IVD26_000209"
     CDS             complement(65443..65871)
                     /locus_tag="IVD26_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078219.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(65931..66689)
                     /locus_tag="IVD26_000210"
     CDS             complement(65931..66689)
                     /locus_tag="IVD26_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAP6078220.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            66984..67181
                     /locus_tag="IVD26_000211"
     CDS             66984..67181
                     /locus_tag="IVD26_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078221.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            67287..67769
                     /locus_tag="IVD26_000212"
     CDS             67287..67769
                     /locus_tag="IVD26_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078222.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(67827..68423)
                     /locus_tag="IVD26_000213"
     CDS             complement(67827..68423)
                     /locus_tag="IVD26_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP6078223.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
BASE COUNT        22582 a        11723 c        14575 g        19746 t
ORIGIN      
        1 caaaaaagaa gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc
       61 aataatagga acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa
      121 aaatagagga attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga
      181 tgttgcagca agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg
      241 atacgataat gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct
      301 ttgtgttctg tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct
      361 cggcggattt ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg
      421 atcgacagca aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa
      481 agctgacctt gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa
      541 atttttagtt aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta
      601 taagattttc gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca
      661 tatttttgtt gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa
      721 aacgatgtat ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac
      781 ttttgtatga aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga
      841 tagaatattt agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa
      901 aaggagaatt gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa
      961 taaaaaatca ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa
     1021 ttatccctct ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag
     1081 gtgttcccga aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc
     1141 agttggatga tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg
     1201 aagaaatcag tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat
     1261 ttgctaaggt cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac
     1321 aaattttgct tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga
     1381 atgaacatat ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc
     1441 aagaagtata taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt
     1501 cgtaaaagta tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa
     1561 aaaagcagtc catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt
     1621 tgagatacaa cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga
     1681 caagctgctt gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga
     1741 agtataacat gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt
     1801 tatgggcagt tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct
     1861 ctttagaagg atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga
     1921 gatgcggtgc gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag
     1981 aagggaaacc agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt
     2041 tgccaggtgt actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga
     2101 aagtcaaccc caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc
     2161 cagttgctca tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa
     2221 aaaataatca gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg
     2281 cagggattac gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag
     2341 tagaagactt gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact
     2401 tcggaaaggt gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga
     2461 aaaaaagaat ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag
     2521 atatcttagg aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg
     2581 aacattgttc ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc
     2641 atgtgttgca aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag
     2701 ttgtcttcaa agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg
     2761 cgacaggagt tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt
     2821 tgctagattc attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag
     2881 aagtagttgc aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg
     2941 aaattgcatt tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt
     3001 tgattgaaca caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt
     3061 atgtaggtgc aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat
     3121 ttaatcaaga agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa
     3181 agctgctgct tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta
     3241 tacaggatat gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg
     3301 gctcaggact tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt
     3361 atgaaatgat gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg
     3421 aagaaaaaat ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag
     3481 taacagacga cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag
     3541 tcgatgcatt agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa
     3601 tcgtagaatt tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat
     3661 tgcttgatct gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg
     3721 attcacaagt acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg
     3781 ttagagggac gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt
     3841 tggatccaaa aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta
     3901 gcggtggtaa gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag
     3961 aagttttttg ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag
     4021 gaactcctgt tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct
     4081 atccaacacc aatgattggt atggtcggat tgattgagga tcataaacat atcactactc
     4141 aggaattcaa aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg
     4201 atggcagtga attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg
     4261 atctatccat tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga
     4321 ttgaaagtgc tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt
     4381 tcaaacatca gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag
     4441 aaactcaatc aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa
     4501 tgatgggaga tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt
     4561 cagcaactga cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg
     4621 caatcgtatg tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg
     4681 gggtcatcca gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg
     4741 acaagaaggt gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt
     4801 ggggctgctt tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc
     4861 tgcaatcgga catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc
     4921 ttttctattc aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa
     4981 tgctcgttcc cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga
     5041 tacggagata ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt
     5101 aaaaagtgct ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc
     5161 aatgattgcc gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa
     5221 cggagcatac gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat
     5281 aagagatgtc cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg
     5341 ctttacgaag gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc
     5401 agattcaaac atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt
     5461 agcgaaagaa tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc
     5521 agccgcaagc ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa
     5581 tcaatacatt gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg
     5641 aatgaaatta tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga
     5701 ttcaattgtt cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc
     5761 aaaagaagtc catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat
     5821 tgatattcaa acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga
     5881 atgtatcggt gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg
     5941 tctggaaaaa gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc
     6001 gacgccgtta tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt
     6061 cttttaaaag cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag
     6121 ctggcgtaga tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa
     6181 aaacggaacg tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat
     6241 cggtctttca attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat
     6301 tagcagtggc aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt
     6361 gtgtcaatga tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa
     6421 cggggaaaaa tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg
     6481 ttcaaggaaa tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag
     6541 gtaatgatta tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga
     6601 caggagaaac gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt
     6661 caaatgggta ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat
     6721 caaaactgcc agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct
     6781 atgtttcttc cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca
     6841 ctggtggagg gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa
     6901 tcaaacttgg ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa
     6961 ttcctgagat ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc
     7021 aagaatcgaa agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg
     7081 aaatcgggaa agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat
     7141 gagaatcgct gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct
     7201 atcgaaaaaa ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata
     7261 tgttttgaaa cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt
     7321 tgattcaaaa aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga
     7381 tttgatcgta ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga
     7441 taaaagaatc atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat
     7501 acgtgatgcc tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca
     7561 aggtgtagat actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac
     7621 gttcgattct ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat
     7681 tagtgaaatt attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca
     7741 gataaaactg ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt
     7801 tcaacaggag gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa
     7861 gaagtgacag ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc
     7921 catggtggtc ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa
     7981 aatatccaac caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg
     8041 aaaccagatg tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg
     8101 ctccgtagtg cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat
     8161 gaagaagtac tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa
     8221 ctagcggcaa aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta
     8281 acggattggg tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa
     8341 acgcttcgtt acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg
     8401 gaaaaatatt cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat
     8461 atccgagatg cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc
     8521 gccttgaaac acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg
     8581 gaagcagcgt atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga
     8641 gaagtagatc tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc
     8701 ccttcttata cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg
     8761 acagtagact ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt
     8821 ggacttcttg tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg
     8881 acaaaacgta agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc
     8941 aaacatgtga aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga
     9001 gccgggcaga tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa
     9061 atggaaggtg cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat
     9121 gcagccaaac atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat
     9181 tctattgata tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt
     9241 agacattaga gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa
     9301 catgcaataa gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca
     9361 ggaaatccgg ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat
     9421 tcagcgttaa tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa
     9481 gttcctttgt taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt
     9541 ccgacaaaag cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat
     9601 acttatcaaa tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg
     9661 tatatcaaag aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa
     9721 ggtgtagtcg tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac
     9781 cagcatcgat ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa
     9841 gaattctccc ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa
     9901 gatcataagc gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat
     9961 tcaccagtac cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa
    10021 ccagcggctt tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt
    10081 ttgattgcta cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct
    10141 gaaacgcaag tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta
    10201 ttagagaatc gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg
    10261 gttgcagctg ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg
    10321 gaagaagagc tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga
    10381 gcaggaggac gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa
    10441 aaaatttaca ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt
    10501 ggagaaaaag ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa
    10561 aaaatacaac aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt
    10621 ggtacacttt tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg
    10681 tacttctgat cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga
    10741 agatccagta aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc
    10801 agatatttat ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc
    10861 aatcaaacga gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt
    10921 tgatttttct aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat
    10981 ggattatgtg gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt
    11041 agctgaagcg tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa
    11101 tcaaaaacca atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa
    11161 tcagctgcaa tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat
    11221 gacagatgaa gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga
    11281 tatgacgatc caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg
    11341 gaacgaaaaa ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac
    11401 gacaccaact ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat
    11461 cgccggtacg atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat
    11521 gtctcgggaa gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt
    11581 gtcataagca ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt
    11641 cagcttcgag atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt
    11701 tcgtttatta gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa
    11761 tcccttgttt tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa
    11821 aagcaatatc tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc
    11881 tttgttctgt cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga
    11941 aatgagaggg acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg
    12001 taaaattttc tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg
    12061 aaggctgtga gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa
    12121 gcgagtcgtc ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt
    12181 gcgggatttt cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac
    12241 gatataatcg tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag
    12301 atacttcgtt tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat
    12361 caactggaag tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg
    12421 aactggcggt ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc
    12481 tttctgcgac aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat
    12541 ggaccaacgt ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa
    12601 ctattaaaaa tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc
    12661 taaataaaaa cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt
    12721 ggtttgctgc taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag
    12781 caagtttcaa tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat
    12841 tttttttcaa ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta
    12901 aagcagttac tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca
    12961 gataatcatc tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac
    13021 taataaatat gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc
    13081 cgtccatgaa aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg
    13141 aagacagtgc catctcacca tctccagctt cgccgacata agtgattgga taataagaac
    13201 caaggacagt tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa
    13261 aaactttata catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg
    13321 acagttgttc cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa
    13381 taaagaagga gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg
    13441 atccctttgg ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg
    13501 ttgtctataa ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat
    13561 cctttgtgac ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag
    13621 atcattttta aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc
    13681 atatggccgt atcttatttt taagatgact agataatcat tgatatggct aatttctttt
    13741 tcaagaggaa tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca
    13801 tgggtcatag tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc
    13861 aaactgttat aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt
    13921 gctaaatggt attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt
    13981 ttattcatgc tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag
    14041 ccaaggttcc ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg
    14101 acctttctct ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact
    14161 ccaagttcca ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt
    14221 gctaagtcga tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca
    14281 gaatctacct gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta
    14341 ttgatcagct cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac
    14401 gtactaattt ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt
    14461 tcttctagga tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc
    14521 cacatacttt ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata
    14581 tttgcgatcg tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc
    14641 aaagggataa cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg
    14701 cttaaatttt ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat
    14761 attctgctgg gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt
    14821 ttgaatattt ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt
    14881 acactcgact acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc
    14941 atcaatagtt acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc
    15001 taaagcaccg tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc
    15061 atttgtttct aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac
    15121 aattcggtga acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt
    15181 tggtttacga ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt
    15241 ctctgaacca gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt
    15301 gctgacaaat aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac
    15361 gaaaagctcg ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc
    15421 tcgctttgct tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat
    15481 catatccact ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat
    15541 gtagccattt cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc
    15601 agtatgcttt ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg
    15661 gtcaggtgct tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag
    15721 ggctaaaaaa aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta
    15781 tcttatcaga taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa
    15841 acttaaaaaa atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa
    15901 aaaatcaatg ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga
    15961 taaaaaatga aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc
    16021 attctattaa gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga
    16081 atcgctatgc cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg
    16141 gaattagaaa aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat
    16201 caagtagcac aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct
    16261 atcgatggtt cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg
    16321 atcgcctatg atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat
    16381 aattttggag taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa
    16441 ggaaaaggac cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta
    16501 atcaattaca acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc
    16561 gtgccatctg gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg
    16621 gcgcaagcaa ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct
    16681 gttttgtcgc catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg
    16741 tatgggagtg aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc
    16801 gttaaatcga tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta
    16861 gcaaaaaata cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat
    16921 gatactgaaa cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta
    16981 tctgtcgata aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc
    17041 gatctgaaaa attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga
    17101 taagaattat ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa
    17161 tccgagcgtt agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg
    17221 gagaaaacgg agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg
    17281 gctcctatga cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag
    17341 atagtgaaga aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt
    17401 caataaaaga gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg
    17461 aactgacaga aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga
    17521 atcttctagt atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat
    17581 tatcaaaatc cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag
    17641 aaagcgcgaa tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca
    17701 ttatttcaca taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg
    17761 atggacagac gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg
    17821 gaatggtggg cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag
    17881 tttattttaa agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa
    17941 acgaccacat caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg
    18001 gagcgggcag aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat
    18061 ccggacgtat attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg
    18121 caaacggact cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg
    18181 atattcggga aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag
    18241 ataaagaaaa agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa
    18301 actccatcca tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat
    18361 ccaagtggct gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag
    18421 atgttggggc aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag
    18481 ctgtctgtct tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata
    18541 cgatgaacga aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct
    18601 tgatgaaatt aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg
    18661 gataaaaaag agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac
    18721 agcatggtga tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt
    18781 ttctggcgtc cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta
    18841 gctgcaggga tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg
    18901 atggcgtttg ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg
    18961 atgacagtta tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg
    19021 gtagcttatg cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt
    19081 ggactgacac aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa
    19141 aaaatgtcta cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca
    19201 ttgattttag gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat
    19261 cgtcggaaaa atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta
    19321 tttacagcag tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg
    19381 attattttga tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca
    19441 gtagcaggtc gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg
    19501 atcaaaacaa agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta
    19561 gctggattag ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg
    19621 gaactggatg caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga
    19681 acaatcatgg gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg
    19741 attttaggcg tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc
    19801 gttgtgctag acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca
    19861 gaaaaaagac tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca
    19921 ttgtttcgtt tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc
    19981 tttttgctct tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc
    20041 ttgattaaat taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat
    20101 gaaagtattt gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg
    20161 ttctgaatgt gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc
    20221 tgccaacatg cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta
    20281 tttctatatc atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa
    20341 aaagcgtgga ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat
    20401 agagaagttg gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg
    20461 acatgctaac tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt
    20521 tgtgattgcc ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc
    20581 agatgcaaca aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg
    20641 ctttgggact ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa
    20701 gccgatcatc gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt
    20761 tggtgcgaca atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga
    20821 aacaaaagtc gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca
    20881 aaaaggcgaa aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt
    20941 gaaagataca ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg
    21001 aagagatctg gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa
    21061 tggagacaca atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca
    21121 ttaagtaata agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt
    21181 attatcgcag atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt
    21241 tttgtcacag tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta
    21301 aaatcaaaag aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa
    21361 aaacaaggac cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga
    21421 aggatcaatc ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg
    21481 aatcgttcca ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc
    21541 aaacgtggca gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga
    21601 atcgattggc ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa
    21661 ataagagaag caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg
    21721 ccagatgagc ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg
    21781 gaagaaaaag aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat
    21841 ttggaaagta aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt
    21901 cagcaagcaa tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta
    21961 gagtcacctt ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt
    22021 gggataccga tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa
    22081 aataaattga aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg
    22141 agtcaaaaac gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt
    22201 gaagacgatg tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga
    22261 acgattgatc cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca
    22321 acgaaaatcg gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa
    22381 gaaatgatgg agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat
    22441 gaagcaattg atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg
    22501 ataagcgctt ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac
    22561 tatgcctgga ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta
    22621 gatatgggtc ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga
    22681 atcaattaca gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt
    22741 ctagaaaagt ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct
    22801 tggatttaaa tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact
    22861 aagaaaaaac cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa
    22921 caaaactgta taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa
    22981 aatagaaaaa atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat
    23041 gctgttaata tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt
    23101 gtatttctca taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt
    23161 tattcactgt ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg
    23221 acaaatggca aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc
    23281 agatttccca gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt
    23341 acctgattta tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt
    23401 attagaccaa cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac
    23461 tgctggacaa gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct
    23521 tcttccaggt tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc
    23581 ttttttatgg tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct
    23641 accaccacaa attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt
    23701 gaagaaacga aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca
    23761 aggtgatttt tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta
    23821 tatccaaaac aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac
    23881 acttgcacaa aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc
    23941 gcttgcagta tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc
    24001 agtcctaatc gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc
    24061 aacccgctac cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg
    24121 cttccgtaaa tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat
    24181 cgaagcaact aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca
    24241 aaaggtttca gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca
    24301 aattgcaatt tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa
    24361 gcaatcacag atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt
    24421 gaagatgttg ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc
    24481 ggagaagacc gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc
    24541 ggtcttgcgt tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc
    24601 gaagcaatgg acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact
    24661 agaaatctac ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg
    24721 cattcggata atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct
    24781 tccaaccctt atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt
    24841 gttttcctag aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct
    24901 tacgaagttc ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc
    24961 acatacggag caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat
    25021 atatctgttg aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt
    25081 caatccgtgg aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc
    25141 gttgccgcgc aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca
    25201 atcggacgag tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg
    25261 ttgccaaatg caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag
    25321 aagggacgaa acaaagtcat ggcttatcaa tttaaattgc cggatatcgg tgaaggaatc
    25381 gcagaaggtg aaatcgtcaa atggttcgtc aaaccaggag atacgatcaa tgaagatgat
    25441 acattactag aagttcaaaa tgacaaatca gtagaagaaa tcccgtcacc tgttacagga
    25501 acggttaaaa atgtgattgt tccagaaggt accgtagcaa atgttgggga tgtattagta
    25561 gaaatcgatg caccaggaca cgaagacaat gaaggggaca gtggtgtagc cgcagaatcc
    25621 caaactccag ctaaaccggc tgctgaaccc actgttgata cagaatcagc tggatcgtca
    25681 agcgaaggag tcttccaatt taagttaccg gatatcggtg aaggaatcgc agaaggtgaa
    25741 atcgtcaaat ggttcgtcaa accaggagat acgatcaatg aagatgatac attactagaa
    25801 gttcaaaatg acaaatcagt agaagaaatt ccgtcacctg tcacagggac agttaaaaac
    25861 gtgattgttc cagaaggcac tgtagcaaat gttggggatg tattagtaga aatcgatgct
    25921 cctggacaca atagtgcacc gtcaactagt gcgccatcag ctgaagcacc aaaagaaaaa
    25981 gtggaaacat caggttcagc aagtgtcgtt gaagctgccg atccaaataa acgtgtattg
    26041 gctatgccat ctgttcgtca atttgcccgt gaaaaagatg tagatatctc acaagtaact
    26101 gcaactggaa aaggtggcag agtaacaaaa gaggacatcg aaaacttctt ggcaggtggt
    26161 ccaagcagtg caccagcgaa atcagaagcg ccagaagcgg cagcaccgaa agaagcagct
    26221 cctgcagcag aaagcaaacc agctgcacca gcaaaaccat tcaagtccaa cttaggagac
    26281 ttggaagaac gtgtagcaat gacgccaaca cgtaaagcta tcgctaaagc aatggtcaac
    26341 agtaagcata cagctccaca cgtgacattg catgatgaag tagaagtgtc taaactatgg
    26401 gataatcgga aacgatttaa agaagttgct gctgcaaatg gtacgaaact tactttcttg
    26461 ccatatgtcg tgaaagcttt aacagcgact gttaagaaat acccagtatt gaatgcatct
    26521 atcgacgatg caaaccaaga aatcgtttat aaacattact acaatatcgg tattgcaact
    26581 gatacggatc acggactata tgtaccaaat gtgaaagatg cagaccgcaa aggaatgttt
    26641 gctattgcag acgaaatcaa tgagaaagca aaattagctc atgacggcaa actatctgca
    26701 gaagatatgc gcaatggaac aattacgatc agcaatatcg gatctgtagg tggcggttgg
    26761 tttacaccag tcatcaacta tccagaagta gctattttag gtgtaggaac gattgcacaa
    26821 caaccaatcg taaatgctga aggcgaaatc gttgtcggtc gtgtgatgaa actgtcatta
    26881 agtttcgatc accgtatcgt agatggagca actgcgcaac aagcaatgaa taatatcaaa
    26941 cgtcttttag ctgatccaga gctattaatg atggaaggat gataaacaaa tggtagttgg
    27001 agattttgct gtagaattag atacagttgt aattggtgcg ggacctggtg gctatgtagc
    27061 tgccatccgc gctgctgaaa tgggacaaaa agtagcaatc attgaaagag agtatattgg
    27121 tggtgtttgt ttgaatgtcg gctgtattcc ttcaaaagca ctgatagctg caggacacca
    27181 ttatcaagag tcactagatt ctgaaatgtt tggagtaact agtgaaaacg tcaaactaga
    27241 ttttgcaaaa acacaagaat ggaaagaaaa caaagttgtc catacgttga cttctggtgt
    27301 tggtttccta ttaaaaaaac ataaggttga aacaatcgaa ggagaagcgt tcttcgtaga
    27361 tgatcacaca ctacgcgtca ttcatccaga ttcagctcaa acttattcgt tcaataacgc
    27421 aatcatcgca acaggttccc gtccaatcga gattccagga tttaaattcg gaggacgtgt
    27481 gttagattct actggcggat tagcattgaa agaagtacct aagaaatttg tgatcatcgg
    27541 tggcggtgtg attggtgccg aattgggcgg agcgtacgca aacttaggag cagaagtaac
    27601 gattcttgaa ggctcaccac aaattttacc aacttacgaa aaagatctag taaaattagt
    27661 agaagatgat ttcaagaaaa aaggcgtaac agtcgtaacg aatgcaatgg cgaaagaagc
    27721 agtcgataac ggtgacagcg tgacagtgaa atatgcagtg gacgggaaag aagaatccgt
    27781 tactgctgat tatgtgatgg tcactgtagg tcgtcgtccg aatacagatg atatgggctt
    27841 agaacaagcg ggtgtcgaag taggagaacg aggattgatc acggtggata aacaaggacg
    27901 tacgaacgta cctaacatct atgccatcgg tgatatcgtt ccaggggcgg cattagcaca
    27961 caaagccagt tatgaagcaa aaatcgctgc tgaagcaatc tctggcaaaa aagtagctgt
    28021 agattataaa gcaatgccgg cagtagcctt cactgatcct gaattggctt ctgtaggtat
    28081 gacgatcaaa gaagcaaaag atgctggtat cgaagcaaaa gcatataaat tcccattttc
    28141 agggaacggt cgggcattat cgcttggtaa aacagaagga ttcatccgtc tagttacgac
    28201 gatcgaagat aacgtgctta ttggcgcgca aatcggtgga gtcggcgcaa gtgatatggt
    28261 ctctgaatta gctttagcaa tcgaatcagg aatgaatgct gaagatatcg ccttgacgat
    28321 tcatcctcat ccatctcttg gcgaaatcgt catggatgct tcggaattag cattaggttt
    28381 accaatccat atttgatttg aataatacag gcgaaacgca actgaaaaat cagttgcgtt
    28441 ttgtttttta gaattatcaa taatattatt atgtaaactt aaaaatatga caacttcttg
    28501 gtttattacc acttcctatg ctacactgaa gaggaatatg aaataggaga gttgaagatg
    28561 caagaatatc agtatccact tgatttagat tggacaacag acgaaatggt cattgtaatg
    28621 aagatgtggg aagatctgga acgtgcgaat gaaaaaggga taaacaatga agcttttttg
    28681 aagacttatc agcagtttaa aactgttgtc aaatccattg gtgaggaaaa acgattggga
    28741 cgggaatttg aaaaagcttc cggttattct ttatatcgta cagtgcagca agcaaaaaaa
    28801 aatccaaaca aaactttgag aatgaacggg tgagataaat ggaacagatg attgatcata
    28861 tcaagtcctg gcttgaagaa gctggtgaga aaatcaaatc ttctcaacaa acattaacaa
    28921 tctcgcaaaa atcaaatcga acggatctag taacaaatgt cgatcgaaac atccagaatt
    28981 ttctaatcga aaaaatccat tcctttgatc cagaggcgaa aatattggca gaagaagaag
    29041 ggtgtaatca attatcggat ctcgatggaa gagtctttat catcgatcct attgatggca
    29101 ccttgaattt tgtgattgaa ggggaaaatt tttgtattat gctcgctgtt tatgaatccg
    29161 gcgttggaaa gcttggtttc atttatgacg tgatgagaaa tgaacttttt tggggtggaa
    29221 aaggaatagg cgtgtataaa aatgatgagc cattgcctag accagcaaat aaatccttat
    29281 cggaaggctt acttggtgtg aatagttatc ttttcggtca taataaatat ggaatccgag
    29341 aaattgcgga aagcagcatg gggacacgta tgtacggatg cgctggtctt gaactagtgg
    29401 caatcttgaa aggaaaccac attgcttata tttcaaacct tagcccttgg gattatgcag
    29461 cgggaaatgt cttattggaa gagtttggta tggtaacaag cggtcttttt ggtactcctt
    29521 tgacatttga aaaaagggaa tactatttag cagggacttc ttgtgcatat gcagaaatcg
    29581 cagacctttt gaaaaaagaa ggctgaaaaa aaggtagaaa tcattcacaa aaatgataaa
    29641 aacgagcaaa agattaattt tctcgaaaaa atgaaaacat tttactatat ttcatgaaaa
    29701 aagtctgcta taattagcag tcgagtaaaa tttgccctgt cataaagaac caataaaaaa
    29761 ggagttagtt acattgaatt atagaaacga tatccgtaac gtcgcaatta ttgcccacgt
    29821 tgaccacgga aaaacaacat tagttgatga actattaaaa caatcagata cattagacgc
    29881 acatacgcaa ttgcaagaac gtgcgatgga ctcaaatgcg ctagaaaaag aacgtggtat
    29941 cacgatttta gccaaaaaca cagctgtaga ctataaaggt attcgcgtaa acatcatgga
    30001 tactccagga cacgcggact tcggtggcga agtagaacgg atcatgaaaa tggttgacgg
    30061 cgttgtgttg gtcgtagatg cgtatgaagg aacaatgcct caaacacgtt ttgtattgaa
    30121 aaaagcactg gaacaacata tcacaccaat cgttgtcgta aacaagattg acaaaccttc
    30181 tgctcgtcct gagcatgtcg tagatgaagt tcttgaacta ttcatcgaat taggagcaga
    30241 tgatgatcag ttagactttc ctgtgattta tgcatctgca ctaaatggta cgtcaagctt
    30301 gtcagatgat ccagcagatc aagaaccaac catggcacct atttttgata caattattga
    30361 aaaaatccct gctcctgtcg ataacagcga cgaaccatta caattccaag tttcattact
    30421 tgactacaac gattatgtag gtcgtatcgg aatcggacgt gtatttagag gaacaatcaa
    30481 agtaggagac caagtagcat taattaaatt agacggaaca gttaagaaat tccgtgtaac
    30541 gaaattattt ggtttctttg gactaaaacg tctagagatt caagaagcaa aagctggaga
    30601 cttgattgct gtctcaggta tggaagatat ctttgtcggt gaaacagtta ctcctgtgga
    30661 tcatcaagat gcgttaccta tccttcacat tgacgaacca acattgcaaa tgactttctt
    30721 agttaataat tcaccatttg ccggtcgaga aggtaaattc gtaaccgctc gtaagattga
    30781 agaacgtttg atggcagaac ttcaaacaga tgtatcctta cgagttgaac caacaaactc
    30841 tccagatgca tggacagttt ctggtcgtgg agaattgcat ttgtctatct tgattgaaaa
    30901 catgcgccgt gagggatacg aattgcaagt atctcgtcca gaagttattg aaaaagaaat
    30961 cgacggtgta aaatgcgaac cgtttgaacg cgtgcaaatc gatacaccag aagaatatat
    31021 gggtagtgtt atcgagtcct tgagcttacg taaaggtgaa atgcaagata tggtccatac
    31081 aggaaacgga caaatccgtt tgacattctt aacacctgcc cgcggtttga ttggttattc
    31141 aactgaattc ctttcaatga cacgtggtta cggaatcatg aaccatactt ttgaccaata
    31201 tctgccaatg cttcctggtc aaattggcgg acgtcaccaa ggggcgcttg tttcgatcga
    31261 tacaggaaaa gcaacgactt attctatcat gagtatcgaa gaacgcggta cagtcttcgt
    31321 agaaccaggt acagaagtat atgaaggaat gattatcggg gaaaacagcc gtgataatga
    31381 tttgactgtc aacatcacga aagcaaaaca aatgacaaac gtacggtctg ctactaaaga
    31441 ccaaacatct gtcatcaaaa aaccaaaaca attgacgttg gaagaatctt tggaattctt
    31501 gaatgatgat gaatattgcg aagtaacacc agaaagcatt cgcttgagaa aacaaatttt
    31561 agagaaaaat gctcgtgaaa aagcatctaa aaagaaaaaa taatctgtaa aaggatgaag
    31621 agagaaacca gcttgttata aaaaatagct ggtttctttt tttgtccaac tcttttctgt
    31681 ggagaagtca tctttgtcaa tggacataaa ttcagaaaat acgccgaaag acgtttaaaa
    31741 gacttttaaa aaacttattt ctagagagtt tttgtttcat aataagataa tgtttcacga
    31801 aaggagatca acttgtcctt cgaagaaaat cgaagtaaaa tggcaagaga aaggagcggg
    31861 aagatgaacg acttattaaa acaatacttt ggctatgatg agtttagacc tggtcaaaaa
    31921 gaaattatcc agaaagtcat tgatcaggaa aatgtattag gaatcatgcc taccggaagt
    31981 gggaaatcaa tctgttacca gcttccagct ttactattag atgggcttac tgtggttgtg
    32041 tcccctttaa tctctttgat gaaggatcag gtggacgcgg cgaatcaatt aggtataccc
    32101 gccactttta tcaatagctc gttagatggt tacgaaacag ctagacgctt ccaagaaatc
    32161 gatagacagc agtaccgttt actttatatc gctcctgaac gttttatcat gccggatttt
    32221 atccaagcaa tgaagcgatg gaacgtccgt atgatcgcta ttgacgaggc acattgtatc
    32281 tctcagtggg ggcatgattt ccgcccaagt tatttacaga tggcgaacca gctagatcaa
    32341 ctgccaaatc gtcctgtaat tgttgctttg acagctacag cgactgtgca agtagctgct
    32401 gacataaaaa gacttttaaa aattccagaa aacaaccata ttcagactgg ttttgaacga
    32461 gaaaatctac gatttcaagt aattaaagat caaaaaaaag aacaatatct aatcgaatat
    32521 ttaaagatca acaaaaatca atctggtatc atttatgcag caacgagaaa agaagtagac
    32581 cgtctctatc atttgcttaa aaaattcgat ttttccgtgg gtagatatca tggtggtcta
    32641 aatgagaatg agcgaacaga aatgcaagaa gcctttttat acgatcgctt gcagctgatt
    32701 gtagcgacaa atgcatttgg tatgggtata aataaaagca atgtccgttt tgttatccat
    32761 tatcaaattc ctggctctct agaagcatac tatcaggaag ctggtcgggc gggaagagat
    32821 ggtctttcca gtgaagccat cctgcttttc tctcctcaag atatccaagt ccaaaagttt
    32881 tttatccagc agtcccaaag agaagaaggg caaaagcaaa aagaatatga aaaattaaaa
    32941 gcgatgacag aatacgtgta tattgagtcc tgtcttcagc aatacatcct aaactatttt
    33001 ggcgagacaa gcagtccgtg caaccgttgt ggtaactgtt tagatgacag agaaatagta
    33061 gaagtaacga cagaagcaca gatggttctt tcttgcttaa aacgtatggg tgagaactat
    33121 ggtaaacaaa tgctgatgaa agtcttagca ggatcgaaag aacaaaagct gcaagcttta
    33181 ggttttggac atttatctac ctatggactg atgaaaaacc aatcgcaaaa agaaacgatg
    33241 cagttaattg aatatttgat atcgaatggc tatcttctga ccatcaatgg tgagtatcct
    33301 gttttgaaag taacagaaag agggatacaa gtattgaaag gacaagaatc tgtttatcga
    33361 aaggaaccca agaaagtcca gcagctatcg gatgaagaaa ccgatacact atttgaagtg
    33421 ctgcgggaac tgcgaacgga tctagcatca gaagcaggcg ttcccccgta tgtcgtattt
    33481 tcagattcca cattgaaaga aatgagccga atacgtccat caagcagatt ggagatgctt
    33541 cagataaaag gagttggcca aagcaagctt gataaatatg gcgaagcctt tttatctcgg
    33601 ataaaaaatg cggactctaa cgttctggat aagtagaaag aacgaatacg taaaaatgaa
    33661 taaaaacaac tggttaaatc tgtttttttt gctccttatg aaaatcaaat atgttataat
    33721 taaggaatta gaatgggagg taagcacaga tggattcttt gtcgaaaaaa cttgcgatcc
    33781 aagtattaaa tgatgaagca gaacggatca aacgattaat ccgaaatcaa aacaacagtc
    33841 tctgtatctc acaatgcaaa gccttcgaag aagtggtaga tacacagatg tacggctttt
    33901 cccggcaagt cggttttgct gtccgtatag gagtaatcgg aaagaacgag ggccagctga
    33961 tgttaagtga gctagaacga gaattgaatc agttatatag tgaggtttac caagaaattt
    34021 atgataaaaa agaagttggc aaggaggaat agacttgcct aagaaagtga aaaaaaggca
    34081 tctattagac tatagcatct tgattcccta tttaatttta tgtgtattgg gattgatcat
    34141 ggtatatagt tctacgtcgt atctattatt agaaaacgga caaaatccgt ccgcatcagt
    34201 cattaaccag agtatttttt gggtgcttag cttgattgct atcgcactac tttataaaat
    34261 gaaaacagat gttttgaaaa accagcgttt gatcatggca gccatcgcag ttttgacgat
    34321 tttgctgctg attgttgtgt tttttggtaa ggagatcaat ggggcgaaag gttggctgca
    34381 aattgcagga ttctcgatcc aacctgccga atacctaaaa atcatttcta tctggtacct
    34441 gtctctgact ttatctaaaa gacaaaacag tgtacaaaaa gattttcttg ggactgtgaa
    34501 acgtccactt gcaatggtta tcggacttac tgcattagtc gctattcttc ccgattttgg
    34561 taatgcggca gttatctttt tgattatttt ggttctgctt ttagccagcg gagtcaatta
    34621 tgtgtatact ttgattgtag gagtaggagg cttttgtcta agtactttta cgatctggct
    34681 gatcaatatc acaaacggaa agatcttacc cggacgttta cagtatatct ataatcgatt
    34741 tgctatttac caaaatcctt tctcagacga attaaataaa gggcatcaac tagtcaacgg
    34801 ctactatgcc atgttcaacg gaggactatt tggcagggga ttaggtaaca gtatccagaa
    34861 aaaaggattt ttacaagaag cacaaaccga ttttatttat gcaatcgtag tggaagaact
    34921 gggagtgatt atggggattt tgatattagc gttgctattc tttatgattg tgcgcattgt
    34981 ccttgtaggt atccgttcaa aagatccgtt caattcgctt ttgtgcattg ggatcggcgc
    35041 aatgtttttg atccaagtat ttgtcaatct tggaggaatt actggcgtta ttcctttgac
    35101 agggatcacg ttcccatttt taagtcaagg aggctccagt ttgctgatgc tttcgatttg
    35161 tgtcggcttt gtcctcaaca tcagtgcgga tgaaaaacgc aagagcttag gtttataata
    35221 aaaaaagatg taggagtggt tcgatgaaaa aagttttagt tgctaacagg ggtgaaatcg
    35281 ctgtacgtgt atttcgtgct tgtacagaat taggaattaa aactgttgga atctatgcag
    35341 aagaagatga atattccgta caccgtttca aagcggatga agcatattta gtaggacaag
    35401 gaaaaaaacc gattgatgcg tatctagata ttgaagggat catttctatc gcgaaagaat
    35461 gcggagctga cgctattcat ccgggttacg gtcttttgtc ggaaaacttg aattttgcgc
    35521 aacggtgcga agaagaaggc atcatttttg ttggacccaa actgcatcat ttagatattt
    35581 ttggagataa aatcaaagca aaagctgcag ctatcgaagc ggggattgct tcgattccag
    35641 gcacagatgg accaatcgct tctatagacg atgccttgga gtttgcgaaa caatacggtt
    35701 atccgattat gatcaaggca gctctaggcg gcggcggacg cggcatgcgt gtagctcacg
    35761 atgaaaagag tgcaagagag ggctacgaac gtgcgaaaag cgaagcaaaa gcagcctttg
    35821 gtagtgatga agtgtatgtt gaaaaataca tcgctaatcc taagcatatc gaagtacaga
    35881 ttctcgggga tacgcatgga aacgtcatcc atctttttga aagagattgt tctgttcagc
    35941 gccgtcacca aaaagtagta gaagtagcgc cttgtgtctc tatgaatgaa cagcaacgtc
    36001 aaaaaatctg ccaggcagct gtccaattga tgaaatatgt cgggtatgtc aacgcaggta
    36061 cagtagaatt tcttgttgaa ggagatgatt tttactttat cgaagtcaac cctcgcgtcc
    36121 aagtggaaca tacgatcaca gaaatgatta cagatattga tatcgtaaca acgcaactgt
    36181 tgattgctca aggtttggat ctgcataaag aaatcggatt gcctcagcaa gaaggaatta
    36241 aattaaatgg ttcagccatt caatgccgaa tcactacaga agacccgttg aataactttt
    36301 taccagacac agggaaaatc gatacgtatc gttcacctgg tggttttggc gtacgtctgg
    36361 atgtcggaaa tgcttacgcg ggctatgtag tgacaccgta ttttgattca ttgctagtaa
    36421 aagtatgtac gcatggtgct acctttgaaa cagccattca gaaaatggaa cgttgcttga
    36481 aagaatttag aatccgtgga gtgaaaacaa acattccatt tatgctcaat gtcatcacac
    36541 atcctgaatt ccaatcagga aatgcaaaaa caaccttcat tgatagtaca gcaacattat
    36601 ttgaatttcc tcgactacga gaccgcggaa acaaaacgat gaaatatatc ggtgaaatta
    36661 ctgtgaatgg ttttccaggt atcgaaagtg gcgaaaaacc attttatgaa gaaccacgta
    36721 tgcctaaaga tctaatcaca agaactgatt acgtaacggc taagaatgta ttagatgcga
    36781 agggtgccga tgctttggtc gaatggatca aaggacagga aaatttgttg ttgacggata
    36841 cgacatttag agacgcccat caaagtctgc tagcaactcg tgttcggaca aaggatttca
    36901 agcagattgc acgtttgact ggagaaggtc ttcctgaact cttttcaagt gagatgtggg
    36961 ggggagcaac atttgatgtg gcttaccgct ttttgaatga agatccttgg caacggttga
    37021 gaaaaattcg ttctttaatg cctaatacgt tgctgcaaat gcttttcaga ggttcaaatg
    37081 ccgttgggta ttctaattat cctgacaatg tattggtgga atttgtcaaa gaagcagcag
    37141 cgcaaggaat cgatgtattt cgaatctttg atagtttgaa ctggactcca caaatggaaa
    37201 aaagtatcca agctgtacgg gatactggta aaatcgcaga ggcagctatt tgctatactg
    37261 gcgatatcaa cgatccaagt cgggcaaaat acaatgttca gtattataaa gacatggcaa
    37321 aggaactaga acaactgggt gcgcatatca ttgcaatcaa agatatggct gggctgctta
    37381 aaccgcaggc agcttatcgt ttgattagtg aattgaaaga aacgacagat ctgccaatcc
    37441 atctgcatac tcatgatacc agcgggaatg gaatcatcac ttattctgct gcttcaaaag
    37501 caggagtaga catcgttgac gtggcaatga gtgcaatgag tgggaatact agtcagccta
    37561 gcatgagcag cttgtattat gcactggtca atggtccacg gctgccagaa atcacgattg
    37621 aaaatgcaca gaaattaaac cattattggg aagatgtgcg catgtattac aaaccgtttg
    37681 aaaacggctt gaatgctcct gaaacagaag tatatatgca tgaaatgcca ggaggacagt
    37741 attcgaatct acagcaacag gcaaaagctg tcggattagg tcatcgctgg gatgaaatca
    37801 aacaaatgta tcatactgtc aacttgatgt ttggcgatat cgttaaagta actccatcat
    37861 ctaaagtagt tggagatatg gcactattta tggtccaaaa tgatcttaca gaagaagata
    37921 tttatgaaaa aggcgaaaca ctaagtttcc ctgaatctgt tgtgactttc ttccaaggag
    37981 aactagggca acccgttggc ggatttccta aaaaattgca aaagattatt cttaaaggca
    38041 gacctgcatt gaatgaacgt ccaggtcttt tggctgaatc agtcgacttc aacgaagtaa
    38101 aaaaagaatt ggcagaaaaa attggctatg aaccaaaaca agacgaagta ttaagctatt
    38161 tgatgtatcc gcaagtcttt ttggactatc aaaaagcata taatcaattt ggcgatgtta
    38221 cattactgga cacaccaaca tttttccaag gtatacgttt gggtgaaaca atcaatgtac
    38281 aaatcgaacg cggaaaaacg cttatcattc gtttagatga aatcggagaa cccgatatcg
    38341 aagggaatcg cgtactgttc ttcaatttga atggacaaag acgtgaaatc actatcaaag
    38401 ataattcgat catcagtacg gtccaaaccc gattgaaagc tgaaccgaca aaccgagaac
    38461 aaattggagc aacgatgtct ggttctgttt tggatgtatt agtgaaaaaa ggcgataacg
    38521 ttaaaaaagg tgatacgttg atgattactg aagcgatgaa aatggaaacg gccatcgaag
    38581 cacgttttga cggagaagtc gcacatgtat atgtgtcttc aggagacact atttcgtctg
    38641 gtgacctttt gattgaagtg actgagaaat aataagcgaa aggtggggaa acatgaaaag
    38701 actgggtttg ttttggctga ttctgctatt agttattgtg gcattctaca tggaaccagt
    38761 cttgtttccg ccaaaacttg aagtgaagga aaactctgat caacaaatat caaaccaaat
    38821 gacaacgtgg aaataccagg agcttaaagc aactggtttt tctacttata tcggaaaacc
    38881 gatcgatcag ctggaaaagg attttggcca agcctatgat cgattaacta gcggatttgg
    38941 ttttgaaaca agatattatg aaaataaagc tagtcatctc acatttgaag cgaacatcca
    39001 agacagcaga gtcacaactg ttaaagtact gcaaacaggg cctgctgata tcgcgccgtt
    39061 ttatttaggg atgacgatgc aagatcttac gaaaatcact actatctata ctaatttcac
    39121 ttttgagtac catgatacag aagttggaat cgaactaatg gaagaggata tgaattatcg
    39181 tccgctaatt gcttttgata acgacacttt tgctatttta ttttttgatc aaacaacaaa
    39241 cggcctattt tcagttgtgt atttagataa agatagtctt ttgaaactat tgccatatca
    39301 agtgtttggt gaaggccttc cacattatca agcagataaa tcggctgatt gggaatcaat
    39361 caatcgcgtt aaagaacgaa aaagtacgac tttattaaat atgcttagaa gagaagacga
    39421 acttcccata tacaatcaaa cacttgcctt tcaaaaccac agtcagctgc tactacatga
    39481 ttttttgaca aggcctgagg aaatattgtc agaggaacgt atggctgatt ggcaaaaatc
    39541 gctaggcagt gctcaaacga cagtgaaatt ctcactgacg aatgatgaat tggagaagtt
    39601 aatcagtaaa caaaaattag aaaatactag tgggctattt attcatccgg cgattgacgc
    39661 tactttttcg tttttatatt ggtacagcga tccttacaac catgaccgtt tcatggaccc
    39721 gggaacggat tctgtaggca ttgctttttc taaagaaaat atgttagtct tattgcaaga
    39781 agaaaacgga gaaagtagtg atagcagtga tcgttaacga agagctgttt caactggagg
    39841 atcaatgcct ccaagtcgct gaaatgataa aaaagagtaa aacgatggct tcttatcttg
    39901 aacataaaca gtcaatggaa gaatctgcaa aagtttgcca gttgaaagaa gcgttcttgt
    39961 ctaagaaaga agcatttgaa aatgtagcgg catatggtga gtatgcacct gattatcgtg
    40021 aaaaaaaacg agctgttcga aaagcaaaaa gacagcttga tatggatgag catgttgcag
    40081 ctttccgata tagtgaaaca cagctgcaaa gtctgttgga tcaaattgtc caagtacttg
    40141 ccgaagaagt ttctaatgaa atcaaagtag atgcaggtag cccgtttttt gaaacgaaaa
    40201 aacactttgg atgcggaggt aattgtcatg caattagaca atagtgaatt tgaaataaca
    40261 aaacgacgcg ggctgatcgt atgggtctac agcttaaaac aattaaagaa tctgaaaaag
    40321 ttcggcttgt tgcattatgt ctcaagaaga atgaaatatg tcgtgcttta cttaaatgaa
    40381 gagacattgg aagaaacaga agaacgaatc cgtaaattac attttgttcg aaacgtagaa
    40441 cgttcttacc gaccggatat cgaaatgaat tttgccgaaa aaataggaaa caaaacagta
    40501 ttaaaagacg aaggtttcga aattgaagag ctaaatacag aaatccgatt agctgaacat
    40561 ctttaaaaat ctcttatgag cagtttttaa ataaaaaata acttggataa cgatcgattt
    40621 ttgatcattg tccaagtatt tttttggtat actagtacca gtaccatttc taaggagtga
    40681 gtagatgcgg ataatatcag gaaattatgg cgggcgccgt ttaaaaagtt tagcaggggc
    40741 gaacaccaga ccaactacag ataaagtaaa agaatccata ttcaatatga ttggaccata
    40801 ttttgatgga gagacagtat tggatctgtt tgcaggaagc ggtggtttag ctatcgaagc
    40861 agtatctaga ggctgcagtc atgcggtatg cgtagacaaa aattaccaag cgctaaaaat
    40921 catcaaagaa aacatcgaaa ttacgaaaga accagagaaa tttaccacaa taaaacttga
    40981 tgcggacaaa gcaatcgaac ggctagcagc ggagaaacaa caattcgact acttgtttct
    41041 tgatccgcca tatgcaaaac aaaaaataat cgatcaaatc cataaaatgg aagaactggg
    41101 acttttttct aaaaccgcag ttatcgtatg cgaaacggat aaaacagtcg aattgccaga
    41161 aactgtggct ggattccatc aaataagaaa acagatttat ggcataacgg ccgtaactat
    41221 ctatagaaaa gagggaaatc aatgaaacgt gcattattcc caggaagttt tgatcctttt
    41281 acaaaaggtc acttagatac ggtggaacgt gcggctaaat tattcgatga ggtagtaatt
    41341 ggtgttttta tcaatacttc aaagaaaagt ttgtttcccc cagaagaaag aatgacattg
    41401 atcacaaaag ctgtttctca tcttcctaat gtaaaagtca tgcatcaaga aaatcaattg
    41461 acggtagaaa cagcaaaaga gattggtgca gatgcgttga tcagaggcat acgaagtatc
    41521 aaagactttg aatatgaacg agagattgct cagatgaatc atcatctata tgatgaattg
    41581 gaaactgtct tcttattagc aaaaccagaa tatagtcacg tgagttccag tattttaaaa
    41641 gaagtactgc actttggcgg agatgtgagc agctacttac cgccagtgat caacgaagct
    41701 ttagctggaa agcgtgaatc aaatgaaagc taaacaatgg ttgaaaacag tactgattat
    41761 catatttgga atgttgatca ttggatttgt agtagttccc ttgccgtatt atgtagaatc
    41821 accgggagcc acgatcgatc tgaaagaact aattacggtc aatgataagg aagataaagg
    41881 ttctgggtct ttctctctta cctctgttgg tatcaggcaa gctacaggtt tcttagcttt
    41941 aaaagctaaa atgacccctt ttgaagaatt gatcagtgaa gaagaattga ctggtggggc
    42001 gacaaatgaa gaatataatc aaatgcaaca gtattatatg gattcttccc aaaatgcagc
    42061 aatcgaacaa gcgttaaaac ttgcagacaa gccttataaa atggaattca aaggcgtata
    42121 tgtcatgagt gtagagaaaa catcgaattt ctttggcaag ctttcagttg gagatacagt
    42181 aacaaaagta gacgggaaaa gctttcaaag tacagaagca tttatggatt atgtaaaaag
    42241 ccaaaaagtt ggacaaacaa tcgaaatcag ttatttgcat aatggtgaag aaaaaacagc
    42301 ttctggtgat ctgatcgagt taccaacaga taaaaaggca ggaataggta tcacgcttac
    42361 tgaccatacc gagatcgaat cagatacaga tgttcgtatt aattctggct ctatcggtgg
    42421 gccatcagcg ggattgatgt tcactttaga aatctatgaa caagtcactg gtaaaaactt
    42481 gcgacatggt aagcaaattg caggaactgg aacgatcaac agtgaaggag aagttggccg
    42541 aatcggagga atcgataaaa aagtggcaag tgcggataaa gctggcgtag agattttctt
    42601 tgcaccagat gatacgattt cagacgatgt taagaaagaa tatcctgaaa taaaaaccaa
    42661 ctacgaagaa gcaaaagctg ccgctaaaaa attgaattcc tcaatgaaaa tcgtaccagt
    42721 aaaaacagta caagaagcgc ttgactatct agagaaaatg aaatgaaact aaataattaa
    42781 agaggggttg tgacacgagt tctgtcacaa cccctctttt tcgtcaaaaa tcttcacgat
    42841 aaaaataaaa acaaaagaaa aaattgacgt aattagatgt tgaagggacg attttgccag
    42901 agctcactgt ttcttcaatt ttaaatgaaa ggagtaatga atgattttta ctggtcattc
    42961 tttgaaaaaa gaacaatgat agaaaaaatc agcaagaaaa tactagcttc acccaaattg
    43021 atcatttgga tgtctatgat agttcttatc ttttgtatcg caagtggttt tttattatca
    43081 aatttgctat tttatagaga aacagaagag actgctgcaa aagaaatact ttcttcgttt
    43141 agttccagtg gagaagatcc atcagctgaa ggaaacgatg tagaagagga tgctcgtcca
    43201 aaggtcatgt acaccgatat caaaggaagt gtgaaggagc ctggtatcta ttccttttct
    43261 tcagaagaac gggtctatga tgtactaaag cgtgcaggtg gattattaga agaagcggat
    43321 agcgatcgaa tcaacttttc tgcgaagata gaagatcagc aagtcctata tatccctgct
    43381 gtaggtgaag agctgccaga acatcttgat cagttggcat cctcggaagg aaaacagcct
    43441 acagcagatt ccgagcctcc caaaataaat atcaatacag ccactccatc agaacttcag
    43501 cagattcctg ggatcggatc agtcaaagcg caagaaatca ttcgatttag agaagaaaac
    43561 ggatccttcc agaaagtgga agacctgcag gagatttctg gtatcggtga aaagacagtt
    43621 gaaaaactaa aaaacttcgt tacaattaaa tagaatgatt caaaatcgac tggcacgagc
    43681 aataaatgga cgctaatgga tactaagaat aatccaattc taagagcttg gcaggacgag
    43741 gaggtagtat ttttggatag gaaatagctt gattgttcgc aaagaaacat taaaaaaacc
    43801 aatgctgaat gtctatctcc aaaataaaat atctgggatt catattatga atacggctgt
    43861 cagcggcaat aacagtcaag ctctacgaga acgctttgcc aaagatgtac ttagctatac
    43921 agcagataaa gtatttattc tcattgggac gaatgatcta gcagagcata aacaactttc
    43981 taaagaaacg taccaaaaaa tctgcagtgg atgatagttc agctgaaaaa agactatagt
    44041 tctgatcatg ctttctttat cacgccacca gcagtcgatg agacaaaaca aaaatatcgg
    44101 aataacaagt tgatcaaaga atatatctct gttctcacag aagtagcaaa acgccatgat
    44161 tgtgaagtat cgatttttat acggaatttc ttgaacaaat ggattcgaag aatttttata
    44221 atgggctaat ggatgacgga cttcatttcg gcagtgaagg gtaggatctt ttgtcagaca
    44281 ggatgattcg ttatatttaa agaatatttt gtttaagcaa tgagtacttt ttaatcaact
    44341 tgaaaaaacg gaggaatata aaacatgtta gaaaaatctt caaaagcatg cgatacgaat
    44401 aaagaaaaag ttactgataa gtcacataat gaacgcattc cttgggacca gtactttatg
    44461 gctcaggcag tactgttatc tttacgtagt acgtgtacac gtttagaagt aggagcgaca
    44521 ctcgttcgag aaaaaaggat cattgctggc ggctataatg gagcagtcag tggagatgtc
    44581 cactgcatag atgaagggtg ttacgtcgtg gatggacact gcttgcgaac gatccatgca
    44641 gagatgaatg cactcctaca gtgtgcaaaa cttggtatcc cgacggaagg ttcagaaatc
    44701 tatgtcacac attttccatg tttggcctgt acaaaggctt tgttgcaagc tggtgtgaaa
    44761 gggatcaatt atctccatga ctatcgaaat gatccttatg cccaagcgtt gatcgaacaa
    44821 ttaggtgtat ctgtacacca agttgcttta gactcacagc atttttcaaa acttcaaaat
    44881 gaattaacag gaaaacatgt ctagcgtttt agaaaggcat gttcgaaatc ggttgatttt
    44941 tccggcaatt acgtcgatga ttatctgttt gttgtattac actgacaatt ggggttatcg
    45001 tttgcttctt gccggaattt ttttatggtt ttcgctaaaa gaaggacgtt ttatcgcgta
    45061 cttgtgtatt ttgtgtagca taacggtatc catttcttat aggctacaag agtattcatt
    45121 tttagaggaa aaaacaacat ctgcgcaaat tactgtattt acagatacga ttcgtgcaaa
    45181 tggtaatttt ttgacaatgg aaggaaggtt atcagagaat aaacaaaagc tccagctttc
    45241 ttatcaagta aacacagaag cagaattgaa aacatggctt aacttccgag gaaagggaat
    45301 agaattgact gctgaaggcg agttcatctc tccagcaaaa aagcggaatc tttataattt
    45361 tgaccaagaa gcttacttca ggaaccatag aatttctgga cggttccaaa ttcaaaagat
    45421 tgaacagatc accatgcaaa atcactggcg aaactggctt cagagaaaaa gaggatcttt
    45481 tatctccttt gtccaatctg aatttccgca aaaaacaagt gtatatatta attctttatt
    45541 atggggctat aaagatgcag gattcagaga accagaagaa atttttaggg agagtggttt
    45601 gctgcatctg ttcagtctat cgggtctaca catccaattt tatttagggt ggctgtatta
    45661 tttgtttcga cgtatcggat ggccactaca cgtcagtatt attccgttga gtctactaac
    45721 tatctgttat gtttctattg caggaagttc tatttctgtt ttgcgtgcta gtttgctgtt
    45781 tttattgcga ttgctagtca aattgctgaa taagcattat tccaccatgg acttatttgc
    45841 agttgtcttt tggcttcttt tactatttga tcctcgattt ctttttcatg cgggtggaca
    45901 gcttagtttt ttcatgagtt ttttgtttat cctgatttct tttgatggag attggttgaa
    45961 aaaaacggcc tctcacgtcc tgtttactat gatcacgatg ccgttgattg tatggcattt
    46021 ttatgagtgg cctattttag gtagtctttt tacattactg attgcaccgg tattcaagtt
    46081 tctttttctt cctggtgtgt tatttctcac actcttcaat cgctggctgc cggaaacttt
    46141 acttttgctg atagaagagg gattaatctt atttgagcga ataatcgatt tttcttcagg
    46201 gtcgtctctc attataggac gtttgcccct tgtgctatct gggatgtata ttttcggatt
    46261 actgatttgt atggataggt tgaaagaaca acctgtgaaa cacttgtttt atgttggtct
    46321 tttttctttt atttttttga ctttgccatt tttacgcttt tcttcaacga tcgcttttat
    46381 cgatgtcggt caaggagaca gtatcttttt gcaaagtcct tttcgaaaag aaacgatttt
    46441 gatcgatact ggaggtcagt tacactttga aagagaaaag tgggcgcaag gtatgatacg
    46501 tcctcctgct gaaagaaata tcgttccata tctaaaaggt caggggataa gtgtaatcga
    46561 taaactcatc ttgacacacg acgatacgga tcatgtggga gaattaccca cgttatctca
    46621 gcattttact atcaaaaaaa tttatatcgg ttggggcgct ggacgaaatg agccattaca
    46681 aaggcattta tctgaagctc aaaaaaatgg tactgagatc attgaaatca aacatgggga
    46741 caggatcagc ggttattatg atctttatgt attgactcct tttgaaaagg gagagggaag
    46801 aaatgaagat tcgattggtc tatggatgga atataacaat aggcgctttt tatttttagg
    46861 agatttgaat caagcaatgg aaaaacaatt gcttttgatt tatcctaatc tgaaagccga
    46921 tgtagtcaaa ttaggtcatc acggtagccg tacgtcaagt aacacagatt ttctttccca
    46981 tattgaagca aaacatggga ttatatcctg cggcgtaaat aatcgttatg gtcacccgca
    47041 cagcgaagta ttggagacac tagaagaaaa tcagataaaa acatggcgaa cggatcaaca
    47101 aggaatgatc acctatcgct ggcatccagt ttttcatcct catgggctag tggaaacaat
    47161 gatagactag taattctcat ctgctcatgg taggataatt tttgaaagtg gtgagtaatt
    47221 tgagtataca agcagagtta caaaaaatac gtaaagaaaa acttgcatct tgttacttga
    47281 ttttaggaac agaaaagttt ctccaagatc aagttcggac agaaattgtc aaaaaaatcc
    47341 aattagaggg cgaagatgac ttaaattttt taagttttga catggaaaat gcaagtttag
    47401 atgaggtagt agctgaagca gagacgttgc cgtttttcgg agatcaacgg ttagtattcg
    47461 tagagaatcc ttatttttta acaggtgaaa aagtaaacaa tggaatcgaa caaaatactg
    47521 atttattgac ggcttatttg aaagaaccat tagaatcgac tgtattagta ttctttgcgc
    47581 catatgaaaa gttggatgaa cggaaaaaag taacgaaaca attgaaaaaa acagcaatta
    47641 tcatcaatgt ccaacagttg aatgaaaaag aagtacgtca atatctgatg aataccttag
    47701 agaattcctc aatcaaaatg gaacgaagtg caattgattt attcttgagg ttgaccgact
    47761 tagatttatc caaaatgatg agagagttac agaaattggt cctttatgga caaaatcaac
    47821 agcaaatcac ggtaagagaa gtagaagaat tagttcctaa aacgttagaa cataatattt
    47881 ttgacatgac ccaatatatt ttaaaaggga agacggaaca agctttgcgt ttatacgaag
    47941 atttagttat gcaaggggaa gaaacaatca aaattaatgc gattttgctt tctcaattac
    48001 gtttattttt acagacaaaa tttcttgtaa agattggtta tcagcaggca aatattgctg
    48061 aaacattgaa aatccatcca tatcgtgtaa aacttgccat gcaggaagta aaaaaattcg
    48121 atgaacattt gctggtacag ttgtttgatc aattagttga gatggattat caaatcaaaa
    48181 cgggacaaat cgaaaaagaa ttaagttttc aactattcgt tttgcgcaca gggcagttgt
    48241 taagaaatcg ataagaagaa agacgagggc aaagcatgcg ggaaggtcgt ttgtttttgt
    48301 cctttttttg acaaataaaa aaatcggccg aagccgattc ttttatttag cgattttttt
    48361 gcttaaacga gatttgtcgc ggttagcttt gtttttgtgg attagacctt ttgattcagc
    48421 catatcaata gctttaacag cttctttata taacgcatct acgttgtcag cacctgaagc
    48481 tacagcatct tcaaattttt tgattgcagt acgcatagcg cttgtttgag atgaattttt
    48541 cacattagcg ttttcgcttg tacgaacacg tttgattgca gattcaatgt ttggcattag
    48601 tttcacctcc gataacttaa gttcttacgc gtgttaccgc ataattcaac attcattatt
    48661 atacctaaag gcagcgtgct ttgcaatatg aacatgacaa gtttttttcc ttaacagtct
    48721 tttattagga ttttttttca gtaaaaacgg atagtacaag ctgaaaaaaa tcaaaaagac
    48781 gctattgtgg gaggcaatag cgtcaaacca aactagattt ttatttatct atttaaacaa
    48841 agtttgaatg ggaatgtttg gtactaagtt attatataac aaagagaacc gtttgcaaag
    48901 ttttttttga aaagggatac gattccctgt tgttctttgt ttttctatta agaaactgca
    48961 gttattttat aaccagtatc ctttgatcag taaaggctat tctggtgtac cgattatttt
    49021 aatgtattca tcgatatttt ttatcaacat tttttttatg accaactggt tccgacggtt
    49081 ccatttgcca cttacttcca gcacatattt atttaggggc aaacgtaaga tatattttgc
    49141 caaatagcga tctttaagca ggccattgat cacacggtcc tcaagctgca agttgatccc
    49201 agtcagcatc attggctgtt cttgtaaaac gtacgtatca attaaaagac cttcaaaagt
    49261 ttccacaagc gtcttccttt cttttcaaag taacctgaaa acaggcacta attcttccat
    49321 tttgatattc gttgaagtgg atgcgatcat tctttctttt gtccactgta atctagtata
    49381 acaaaaaaga gcagaagagc caaaaagaaa aaagagcatc gaattctata ggaagtctca
    49441 ttggcacggc ctaaattatt acaaaacatt gattaaaaaa agcccctgca tcgcaggagc
    49501 atcccctata tcgttttaat aggtcaatca aaaagcagta tcaaacacat tttgtatcaa
    49561 atcaggaaat aatagataag ctaagcccag aatcaaaagt accgctagaa gaaaccagcc
    49621 gattgttcct atgaaatact ttaatttttc gaacattgta tcacctcgtt gtcagtatat
    49681 cacggatcag taaattgggg gtgttaagaa tctcctaaaa tagacaaaat ttgttctatt
    49741 ttcctaaagc aaatacttgt aagatacagt aagtgatacc agaagcaatg accggtccgg
    49801 cggcgattcc tcttaagaag acaacaccta aaatcgtgcc gaaaacaagt gcaacagtga
    49861 tttgtggatc agaagcaatc aatcctacac ccttggaaga taagacagcc actagcccac
    49921 cgcaaaaaac agctacccag ccaatagggg atttaaaggc ttctaataga tcacgtagac
    49981 cgatttctcc tgttgcgata gggattagaa tagccgctgt gatgatcgtc accccaatat
    50041 tgattccttt gccttgaagc caagggaaaa aggaacggga ggctggtatg agcttcataa
    50101 tcaaaacaaa agctgccgct atcatcagac tttgattttt agctaaaatt gctacaagta
    50161 aaataattcc taaaaaaagc caactttcca tgaaatatat tcctcacttt cttcgaaaca
    50221 atcataacat gtttttagaa agttacaaaa gtaggaattc atccttcaag acctattcat
    50281 aagctgtttt tttcataaaa taaacaaaat cataaaaaaa cactttgctt atttgacaga
    50341 agacagccgc gctttgtata gtggacaaga cttacatttt tttgaagaat cagaaagatc
    50401 aggtaaaggt cttagtaaac gcaagccatt cagaataacc aatattgtgc ttccttcgtg
    50461 tcctacaact ccaagaggta gatttaaaaa ttgcaggaag ttagaagcaa tcaacaagag
    50521 aataacaaga atcgaaaaaa taatattttg tttgatgatc cgccgcattt ttaaagatag
    50581 ccgatgactg tagacaaatt tatttaagtc gcttttcatt aagacgatgt ctgcgatatc
    50641 catagcggca tctgtccctt gccccatagc gacacctaaa gaagcggctg ctaaagcagg
    50701 cgcatcattg actccatcac caaccatcgc atttacttgg taaagttcat tctctttttt
    50761 gactagttgt gttttttctt ccggagtaca gcttgcatag taatgttcaa tccctacttg
    50821 ttcagcaatg gcctttgctg tgccagaatg gtcgccggtt atcatacttg tatggatgtt
    50881 ttgggattta aagtaggaaa ttacttgttg ggtatttgct tttggaatat ctagcagacc
    50941 taaaacagca attaactgct gatctttaga aagataaatc acggttttgc cttgattttc
    51001 caaacgttcg atcatttccg caatctcttt gctgattatc atcgtctcag gatcatatgc
    51061 gtgcttgcca actttccatt gcgcacctaa ataggtagtt tgtaatccaa aaccagtaat
    51121 ttcttctatt ggtaagtatt ggatttcttc aggtattgtg caatcgaaat attgcaaaat
    51181 cgcatgagca agtggatgcg tcgttttttg ttccatagca acaagaagtt gttgtgccaa
    51241 atccttttca tcaaagaaaa agctgtcagt tacaactggt tttcctttag tgagcgttcc
    51301 tgttttatca aaggcaatcg cttttaattc agaaagcttt tctaaatgga taccgccttt
    51361 gattaaaatc ccattttttg cagaatttga aagagcagct agagaagctg gtgtagcaga
    51421 tgcgacaagc gcacaaggag aagccacaac taataatacc attcctcgat aaaagctttc
    51481 atcccaactc caacctagga aaaagtgggg gagaaggatc attagaggaa cagcaagcaa
    51541 aatcaatttt acataattat tttcgattcg ttcgataaat gaagctgttt gagttggcgt
    51601 attctgcgct tcttctacta attggataat cttagcaaag acagtttcgg aactcgtttt
    51661 tgttactcga atcgtgatgg gatttccttg attcagcgtt cctgcataca tctcatcgcc
    51721 taaatatttt tctacaggca cagattcacc gcttaatgca gactcatcga tcgttgcctg
    51781 tgtgctttct aaaaagccat ctatcggaac agctgctcct ttagcgacaa ataccaagtt
    51841 atccaccttt agttgagaaa catctacttc ttgcatttgt ccattttctt ttaataattg
    51901 ggctttttgt ggttgaagat tcatcaaagc agtaatttct ttttgacttt tattagttgt
    51961 gtattcctct aatgcaccgc ttaaacaaaa gatgaatgtc aacattgctc cttcaaagta
    52021 attaccgatc aaacaggcac caatagcagc taaagccatc aataaatcca cattcagtgt
    52081 ccgatcattc cacaattctt tcaagccttc cgatgtttgt ttatatccac cgatgataat
    52141 ggcactgata taaaaaagtg gggtgatggt aagagagaat cggtcgaaga taaaaccgaa
    52201 gatcataaat aaaaggcagc cgattgttgc tgcaaaagct tttttctgat tagtcatcgt
    52261 tattagacct ccttgtcaaa acaaggatag cataataaaa atgtaattga taataataac
    52321 agctaaatga gaacgataat ggttatcatt tggtgattaa gcttgatgtt gtttttatta
    52381 tttataatga ttattattaa agaaaataaa aaaccagaac atttctcaaa taagagaagt
    52441 gttctggttt tttctacatt gcaataaacc aataaccaat caaaatgata ccaaggataa
    52501 tacgatacca gccaaaagcg gtaaagtcgt ttttcttcaa atagcttagt aagaatttga
    52561 tagctaagac ggaaaccaca aaagatacga atgttcctac aagaagaaca acagtttctt
    52621 ccattttgaa tgaattccct tcagctaaat atttgacgat cttcaagccg cttgcgccaa
    52681 acatgacagg aatccctaag aaaaatgaaa actctgtagc gacaaaacgc gaagcaccaa
    52741 tcaagataga tcctaggatc gttgcgccag aacgggatgt tccgggaaca agtgccaaga
    52801 cttggaataa cccaacaaga agagctgctt ggtacgtaaa gtcattcaga gaagtccaac
    52861 gaggtgtttt gtttttgttg cgtttttcga caataataaa ggcaataccg taaacgatca
    52921 aaacaatggc aactggtaag aacttgtgga aatttgcttc taaccaatca tccaaaggca
    52981 aaccaatgat gatggctggt atgcaagcaa cgatcacttt aaaccaaagt gtccacgtat
    53041 cttttttttc taccgttgat ttacttggag aaaatgggtt taacttgtga aaataaagaa
    53101 cgacgacagc caagatcgcc cctaattgga taacgacatt gaacatcgac ataaattgtg
    53161 aactggcatc cagtttgatg aattcatctg ctaggatcaa atgaccagta ctactgatgg
    53221 gcagccattc cgttattcct tcaataatac cgagaatcac tgctttgata atatttgcaa
    53281 aaaacataaa ttccttcctt cccaattaag atacatctta tagtataccg ttattttttg
    53341 agaaacccaa tctgtttttt aatattaaga aaaacttgag aaataaagca gataagtaca
    53401 cgaagagaaa aaagaagaca aagccctcgt tcagactttg ccttttatga ttctctggta
    53461 aaaattaaaa tatccccatt atagaaacga gtcgcgacta tgtgttttcc cgttatcgat
    53521 ataagacgta tcattgatgc cgtggataga aaatcgaccg tttgcataag tgacctttgt
    53581 tacgctgcca tttaaaagcc cagcacgaac aggctgttta ggatcgatca gattaagcaa
    53641 aaaggcgatc gtcaaaccat gagatacgac taaaacattt ccaccaccat ttttttcgca
    53701 gtgatgggcg atatcttcaa atcctgtcca tacacggtct cgcaatgttt cataagtttc
    53761 cgcccaccca gcggtatcta agttgtatac agcattagca atttgttcaa aagaaacttc
    53821 tgtggtaaac atttcatcat atgttttaaa attcaataca cgagggatca caccccacat
    53881 ttccatgtca tatccacctt caagagaccc gaaacaccat tctctaatcc ttttttcaat
    53941 aaaataagga atttcttttc ccttagaatg ttctcctaga ataatacggg cagtttcgat
    54001 tgcacgacca ctgtcactag aataagcaaa tgaaaagtcg acatttttta acccgcgacc
    54061 taaataatga atgccttctt gtccttgctt tgtgaggggt gtatcacacc agccttgtac
    54121 tcgttcaatt gtattgaaca tcgtttttcc gtgtcgtacg atataaagtg tagtttctgt
    54181 cattttattc tcctcctaag tcgttttaac gattgaaaaa aggatttgtc cttttttcct
    54241 gttcaatcgt cgttgcatcg ccatgtcctg gatagactgc aaattcatca ggtaatacaa
    54301 acagctgggt ccgaatacta tgaagtaatt gttctaaatt ccctgtatac agatcggttc
    54361 taccgatact tcctctaaac agggcgtcgc cagaaacgac aaaatcatca aaaataaagc
    54421 tgacgcttcc tatagaatgc cctggggtag ggacgacgcg aaaagacatg tttcctaaag
    54481 tataagtttt catttcaaat tcatattctg caggcgagac aataacatca gcaatatcat
    54541 catgtctacc gagtccagaa agattcaaaa tcggatcacc tagccatttt tgctctagtg
    54601 ggctgacata aactgggatt tgataatacg cgcgtaaagg ttccactgca ccgatatgat
    54661 cgtagtgagt atgggtaagc aaaatcgcta ccggctgttg gtttgttttt ttgatttctt
    54721 gtttgattcg ttccgcatct tctccagggt caatgatcaa aagtgcttct tcgttgtaga
    54781 ccaaataaca gttttcttca atcattcctg tttttaatct ttcgatatgc atgtgcattc
    54841 ctccttgata gccaaaactt ctttcatcca ttagtataac gcattcattg ctaggaaaca
    54901 aaaacaggta cttatttctc tttacttatc tgaattatca gactatatga aaagtatttg
    54961 gatattctaa agagaaggaa agtaagtttt catagcattt taatatgtcc ttgttacatt
    55021 agattcatcc aaaaatccaa attctatatc ctatatccct gcctaatcag cagggtgttt
    55081 ttttatgttt ggaaagagag ctctttttgc taaactaggt tttttcaggt aatcttagag
    55141 agaaagaggt ggtggaaatg atcaaacagt caaaaatatc tgtgcggcac ttagtagaat
    55201 ttattttgcg acgtggaagt atcgacaatc gtaaaaaaag taaccatact gcattagaag
    55261 gagcgagaat ccaccgcaag ctccaaaaag atgcgggaga aaactatgaa aaagaagtct
    55321 ttttaaaaac aacagttcaa ttagatgaat attacctgat cgttgaaggc cgtgcagacg
    55381 gtattttcaa aagagacggt atttattata tagatgaaat caaaacctcc gaaccacgat
    55441 ttgaagattt agaaccagaa caagtggaac ttttctttca tcaagcaagg gtgtatgcct
    55501 atatctatag tcaagaacat gatttacaag aaataaatct gcaattgact tacttccaga
    55561 cggcagaaga agtgatcacg agaaaggttg aacatcagac aagagagcag ttagaaactt
    55621 tttttaaaaa gctgactgaa gattataaag aatggcttgt ttttcaagaa aactggcgca
    55681 ctgtacgcaa tgcctctttg atggctttga aattccccca tgatgagtat aggaaaggtc
    55741 agcgtgaact agcggtagct gcttataaaa cgatccgtac gaaacagaaa ttgtttgtag
    55801 aagcacctac cggaacagga aaaacaatct ctacgttatt ccccgctttg aaagctgtag
    55861 gggaagaaga gggagaaaag atcttttatc taacggctaa aacaataact agacaagtag
    55921 ctgaagatgc tatgacagca ttaaaagata caggagctga agtaaaaagt gtcactttga
    55981 cggcgaaaga caagatctgc tttttagatg agacgacctg taatccagat cagtgcccat
    56041 atgccaatgg ttattacaat cggattaatg aaggtttatg ggatcttttg aatcatgaga
    56101 atcagatcac tcgtgaagtc atcgaaactt atgcaagaaa gcatacactt tgtcctttcg
    56161 aactatcatt agatgtcagt atctggtgtg acgtaatcat tggggattac aattatttat
    56221 ttgatccaac tgtttattta agacgttttt ttgaagatga aaaaaacgag gactatctgt
    56281 ttttgattga cgaagcacat aatttggtga atcgttcccg agagatgtat tcggcagaac
    56341 tatcttatga aaaaacgaaa cgaagtaagg aagctatacc aaaggaattc aaaaaacttc
    56401 atcgccgttt caacaaacta ttaaaagaat ttgattcgat ccgagaaata gcaaaagaag
    56461 atcattggga ttatcatcat caaaaagcac cggctgaatc tttagtaaag gcaggttatc
    56521 aattaagcga aaaaattaaa gaatggctgg cagaatttcc tgagcaccca tcacaagaac
    56581 aattgcttcc ttattatttt gatttgcttc attttttgaa ggtcagtgaa ttttatgatg
    56641 atcactacga aacaacagtc gaaaaaacgt atcgcgatct gatagtaaaa gagttttgta
    56701 ttgatccaag cttgtttctt gagcagtcgt tggataaagg aaaaagcagt attctttttt
    56761 ctgctagttt ttcaccactc tcttattatc aggaaacact ggggggacaa aaaagtctgg
    56821 cttacaaact gccgagtcct ttcccagaag gaaaccagca agttttcatc gcaaattacc
    56881 tagagacgac ttatcgaaaa agggaacaca gtctggcaaa attagtagag acgattcatg
    56941 cttttgctga tggaaaggtc gggaattatt tcgttttctt tccttcttat caatatttag
    57001 atcttgcggt ggaagcattc agacagcaat atcccgacag caatgtgcta atccaagaaa
    57061 cggacatgaa tgaggaagaa cgcgaacgat ttttaacaaa atttcaaaca aatcccgctg
    57121 aaacattgat tggattttgc gtacttggcg ggattttttc agaaggaatc gatttgagag
    57181 gggaccgatt gatcggcagt atgatcgtag gtgtaggttt gccgcagatg aatcatgagc
    57241 aggaactgat caaatcatat tatgatgaga aggaacacct tggatttgct tacgcttatc
    57301 agcttcctgg aatgaacaaa gtcttgcaag ctggtggtcg agtgattcgt ggcatggcgg
    57361 atcaaggaat cgttgtattg gcagatcaac gattttctag tttttcttat cgacgtttat
    57421 tcccacaaca ttggcaaaca gcaagagaag tacgaagtgt tggggaattg gaagaaggaa
    57481 tacagcgttt ttggttatca aaagaagcag taaatcaaaa aaacgaggaa tgacagacgt
    57541 cagcctcgtt ttttgattaa cgatagttag tgaattgcaa ctcgattggt aagtcaagtt
    57601 tacgtaataa agcaatcaca gcttgtagat catcacggtt cttacctgtc actctaatct
    57661 gatcttcttg gatttgtgct tttactttca gtttttcatt tttgatagct gtagtgattt
    57721 tcttcgcgtt ttcacgatcg attccgttga ccaaatcggc agtttgtcga gctttgccac
    57781 ctagagcgtg ttctgattcg gaaaaatgga tatttttgat tggcacattt cttttgatca
    57841 gcttaccaaa taatacatct ttgatctgtt cgattttgaa atcatcatcg ctcaatacaa
    57901 ctagattgct gttctctaat ttgatttcta ctgtagaatc cttgaagtca aagcgattgg
    57961 acaattcttt tgttgtttgc tgaatcgcat tttttacttc ttctgtattg acttctgata
    58021 caatgtcgaa gctagcatct tttgccatag gaaccctcct gatatacata taaatattta
    58081 ccatacatct atcttatcat aggattaggg cagattctta cctgtttgct aaaattcttc
    58141 tcatttgagt tcgaagtatt ttattttaat agataaactg ttattcttac atttggaata
    58201 ccaaagtagg ggagaggtgc ttgtgagtaa aattatgact gcgtatcata aaaatgaaag
    58261 attaaagaaa atagtggtta ttttgataac cggattgacc gctgcggtcg ctttaaatta
    58321 ttttttgatt ccagccaatg tcttttctgc agggatgaat gggatcgctc aaatcatttc
    58381 ctcgctttta tatgaatggt ttcatatcaa gatagacaca ggaacattta tttttctttt
    58441 gaatatccct gtgtttgtat tagggtttct caaagtagga aaacgagcaa cgatccttag
    58501 ttttgtgaat gttgtatgtg tatcggtgat gacgatgctg cttccagtcg gacagatcac
    58561 tgataatatt ttgatgaatg ccctagtagg cggtgtttta ttaggtcttg gcgtaggatt
    58621 atctttaaaa atgggcttta caactggtgg gatggatatc atctctcttg tactttcaca
    58681 aacaactgga aaaacagtcg gaaactacat gctgattcta aatggtatca ttgtagtcat
    58741 cgcaggcttc ttctttaact gggaaagtgc cttgtatacg attatttcca tttatgcaat
    58801 gactcaagta attgatgcca tccacacgag tcatcaaaaa gtaacagcaa tgatcgttac
    58861 cgtcaagcca gaagaggtaa cagaagaact agcaaaacgg atggtacgtg gaatgacatt
    58921 actgccgtct gtcggtggct attcaaaaaa acaagggaac atgatcatga tggtcatcac
    58981 ccgctacgaa atgtatgatc ttgatcagat cgttcatgaa atcgacgacg atgcatttat
    59041 caatatttta ccaactcatt cagtatttgg ccggtttgca aatgaaaacg aacaaaaaat
    59101 gtatcgaaca actggcgtat tgccagaaat aaaaaatcgt tcacaaaaaa aatgaggaat
    59161 caggtttatt ttagaataaa tttaatctat tacatctaat aagaacattt ttataaattt
    59221 aaacgagaat cttacttcta aattctcatt tacaagcagc taaaaaaaga gtatgataaa
    59281 taaaaatcgt gttaaggagt gtcgtacgat gagcgaagca aaccaagaac ggtctggaca
    59341 agaaatagaa ctaatcaaag aacgtattct tgctgccttg gaaatggtga ttgatcctga
    59401 attaggaatc gacatcgtca atttaggctt gatttatgat atagaattca atcctgaaaa
    59461 tggagaaaca gtcattaaga tgactctaac aactatgggc tgtccattag cagatatttt
    59521 aacagaatct atccatgacg cattaaaaga agtgccagaa gtaacgaaag cagaagtcaa
    59581 actagtctgg tatccagcat ggacgacaga taagatgagc cgttatgcac ggattgcgtt
    59641 ggggatacga tagaaatctt ggctgactag ctatgagaag caaataggaa aaacaaaaaa
    59701 gccttttatc ctttctagaa gaaaagagat aaaaggtttc tttgtttata aaattttgtc
    59761 tgctatatta taagttaatt aaataaatgt gttctattga taaaggacat tcaaatccct
    59821 ttccttttgg aatccttctt ttttacatca gtttgatttt cgtatagtat tctttctcat
    59881 cttcacgata aatcgcagcc ccattttttt gttgtgcttt aagactgcca agattttttt
    59941 tatttacaga caaaagtgcc tcatcaatgc cgattttttt tgcctcttgt agtactaatg
    60001 ctaatccttg tgtggcatat ccttttttac gataattagg ggagatgccg taaccaatat
    60061 ggccagcgcc gtttcttaat gtttcgttca gtttatggcg caaattaaaa attcctacat
    60121 actcatgttc atcactttct aaaataaaga cggttgcggg aacgtaactc tcaggaagat
    60181 cgattcctaa agacgttttt tcgcattttt ttacataatc taaaaattca gcaaatgtat
    60241 agccataagc attgttgata aatccactct catttggtcc aaagctagtt tgtagctgat
    60301 aagctttctt taaatctgct tcccatagtt tgatcagttt catcgtattc acctctttaa
    60361 gtaaccttat tcatttgttt tctactatag cactattgtt gtaaatagcc atgcctattt
    60421 ttatttattg tgtcatatcg tattaagaat catcgaacaa tacaaatatg aattacaata
    60481 aaaaaattat ttgaagttcg ttcattcgtt acttatgatc tctagaagaa agaaaacgtg
    60541 aattacttca gcgtctagaa ttccagaagg atagtaatca acagaagaaa taatcaatat
    60601 ccaaatgaaa gaagatagct gaatcgagaa aaagaggaaa aaagaaatga agaaaaaaat
    60661 aaaatagtta ctaatcccag agtcgttcgt ttaacattga aatcgatcat atggataaaa
    60721 cagatttttt caccaaccct caatagatga tggagttgct cggatgaatt atttgtgtag
    60781 atggcataag ggagggcgta cagaaatgaa aaagaacaaa aatatgttct tgacaaaaaa
    60841 cacatgtaat cctaaactaa aagatgtgat gcggctatgg cggaattggc agacgcgcta
    60901 gcttcaggcg ctagtgaggg tgacctcgtg gaagttcgag tcttcttagc cgcataattt
    60961 gtttttttat aaagagaagg tacacctgga gcgatgagaa agaaaataac atattatcta
    61021 aaagaatata ggaaaaattt taaacaacgg aaccagattc aaataaatca aaaaaaattt
    61081 gtgtgaaggt gggacagttt aaaacctaat agattgattc aaatagtaga tttatagatt
    61141 ctgatacaag aaatactggc aaacgatagt taaggaataa agactaaact taaactcaaa
    61201 aagaggtcat gcgaaagaat aaatcgcatg acctcttact atattttgaa tgtgtttaaa
    61261 cgttcaaata atgaatctta gtaccaaccg tttgcttccc agaatgcttt cgccgcttcc
    61321 caagaaccat aacgtgaagt aacatattgt tctgctactc tttcttggtt tgcagcagag
    61381 tagtcaccat ttaagtaaga agaatctaat tggtaacggc cgatgtaacg tccgttcgtt
    61441 gctgtgtaag aaccgcttga ttctttttgt gcgatccatt cttttgcaga gcttgtactt
    61501 gctggagtag cagcagtttc tgttacagca ggagcaggtt gtgtttcagc aacaggcgct
    61561 gcttgtgttt ccgtttgaac cgtttcttgt acaacaggtt gttcagcttg aacaggttca
    61621 gcttggactg gtgcttcttg aacggctgct tgaggttcag cagctgcttg tgcagagcct
    61681 tctgttggga ttgttaattg ttgtcctgag tagatcaggt taatatcaga aattgaattt
    61741 gattctgcaa tggcattgat caaggagtta tcaccaacgt atttttgaga aatcgttgat
    61801 agagtatcac ctgattgaac ggtataagct tcgtccgcat gagcagtcgt tcccatgaag
    61861 aatgcagcgc cggcagccaa agttgttcca aaaagtaaag ttttaagtga tgtcatgaaa
    61921 aatctccttt attcgttaaa aagttttatt tgttgtgttc aacgaggaat actttaacac
    61981 gtgaaaatat ttcataggta aaagaagcat gacaatttat gacaaatcca cgttttttgt
    62041 aacagaatga tgttcgctcg atgtgaaaaa tgatgaggaa tttcacataa tgcagaaata
    62101 atgggattag aacaggtgtt ctgatgagaa aagaaatgta taaataactt gaaagaaatt
    62161 gcttttgttc atcattttat ttacatattg cgtatatttt ttgtattttt gcttgagatg
    62221 ttacaataaa agaaaaagga ggcggttcca atgagtaaaa gataccagaa catcatggta
    62281 gcagttgacg gatcaagaca atcgatcaaa gcgttcgctg aagcccttga cttagcaaag
    62341 gacaatgaag cccacttatt tatcgtgtca atcatcaaca aagttgagct gacccatagt
    62401 gcctatgcct tttcaaaaat ctatgcagat gaaaaacaaa gaacagaagt agccatgctg
    62461 aaaaaaatca atgatgccaa agagtacggc attgctgaga tccacgcaat agttgaaact
    62521 ggagatccaa gaaatttgat tgccaatgtc atccctggac aagaaaatat tgatttgatc
    62581 gttatgggag cgacaggaaa aggtgctata caacaagcat tagttggatc gaccgcttct
    62641 tatgtcgtat cacatgcccc ttgcagtgtg ttggtcgtga agtaatgaga taagggagga
    62701 atagaaaatg gttcgtcctc aagaagtccg tgcgccaaaa gaaaaaatag aaattttagc
    62761 aattattgaa gacggcacac aaacaaagaa gggatactcg atcgctttag taaagtggaa
    62821 aggaaaaaaa ggtgttgctc tgagatggga tggagataac caacaagata aaggattccc
    62881 tgtcacagct aacggttatc atccagcgtg gtttgttctg cctgataaat ttatggaatt
    62941 atacagctat gattatgcaa gagccgcagc atcaatcaaa gcattagata aattaacaga
    63001 agagcagaat gaaatggagg aaaaataaaa aagacgaacc aatcagcctt tagaaaactg
    63061 attagttcga ggagtaaaaa tgaaaaaagg ttatttggga tgaaactaga ataatgcgta
    63121 taacttaaat aaaacttaaa gcaataaaat ggcaagaggg tgaggcaaat ggaagcagga
    63181 aaagtattac aggaagtaaa agcactatgt gcagataaaa aatatgaaga agcgaaaagc
    63241 ctgatcgaaa agaacaaaga aaatttggaa gaaaagtacc cgatcgcaca agaatttata
    63301 gaattaaaac aaggaacgat ccttcaccga ttcaaacatt tttttggtat aacagaatag
    63361 aaaaaacgat taaagatcgg cagaaatttg ctgcatcttt aatcgttttc tttttaaaca
    63421 tgcgagggat tcaattctga ttcttatata aaaaatagat ccaaataata agaaaaatta
    63481 ctgaaagcgt caattcgatg atgtgtgtta ttaatacaga cgttgtttcc caatgcctaa
    63541 aagaaaaaat ttgataagta aaatatacag caggtaaaga ggccagtaaa actgaaaact
    63601 tcttttttgt ccattttatg taatagaaaa gaatgcttat cataataaaa aaaggaatat
    63661 aaaaaacaaa ttgaccgatc gcgatcatac tattgcctcc gataaataaa gtccatgata
    63721 caaaataaca ctttgtgcga aatggcgcaa gcagttttgt ggatttatcc ggtaaaatct
    63781 gtatcgattt tgaaattaga ggagaaactt gctataatca aagtgaaaga aggagtggga
    63841 ttttcatgga tcatgtagtg ttagaaatcg atttgcattt gatcaataat attcgggtga
    63901 tttactatgt tgtaagtaac agtgtcgaac aacgtgtact gacgaataaa ataaatggta
    63961 ttttagcaaa gaaagacgtt caccgattca ataatggtga aggaagttat tatagtatcc
    64021 cagtagaaaa aattatttat acgacagtca aagtcagaga agatctagat accaaaaaag
    64081 catatgaacc tatttttaca acttattgat tgacagcaga tggaggaaaa aaatgaatcc
    64141 atatgaacaa cttattcaag atttgatcga tggaaaaatc gaaaagattg atgtaaaaag
    64201 agaagaatta atggcttttc gagaagcgtg gctgaagttg gagaatcgta aatatgtggt
    64261 gggaaaagcc tcactgaacg gcaatgtgac ttatcattac gatccgacac gtttatttta
    64321 gtatgaagta ttcagaaaag aaccaaagga ggacgatgca gcagcattgt cctcctttga
    64381 ttttacaaaa gtgaaagttt tacttatttg aatagatttt taaatttgtt tttgacactg
    64441 tcgatattta catcttttaa aagattttgg gctttctctt tataaggtcc taattgttct
    64501 ttatgttctt cgataaatcg ttttgcgcca tcgaaattgc cgttcttaat catttccttg
    64561 actttttgaa ataattcttc ttgattcatt ttgaacacat cctttgctat caacatgatt
    64621 ttttacatgg acaaaacgag aaaaactgat ttatccacac gtcaataata tcaaataacg
    64681 atcattttta ctaaaaaaac actcgattct cgcttctaaa gtaggagaaa aatctccaac
    64741 ttgggacgga tggaatttct ttaactgacc catatactga atatataaca aggaggtaga
    64801 aagatgaaag tgattaaata tttgattgga ctggcggcga ttagtggtat tttgctattt
    64861 ggactgaaat attatactga aggaagttat ggagaaatcc ctggtatact tgatcagcta
    64921 aatccattag ttgaaaaagg agaggtctat gtaaagacac aaaaaccaga ggaagtaaat
    64981 gaatatggta cagcaaggta tgtgcagaaa gctgctgatg ccaatgggaa agaacgaacg
    65041 gttgaattta atggtctttc tgtgttaaaa gaaaatcatt atttgaaaat tagcaataaa
    65101 ggagcacaca tagaaacgta tgaggaagtt cctagagaaa aagttccgga gaaagcatta
    65161 gcaattattg ggtaaatcag tttttgtatt aagaatacgc ccgattttat tattcataat
    65221 ttaattatgt aaactaaata caagtagtaa aaataataca ataatccccc tgcaaaaaga
    65281 ttgttctttt acagggggtt cattttttca gcaagcacat caaattggga tggcagggtt
    65341 cgaacctaca attgcttgat tcagagtcaa gtgccttacc agtttggcta catcccattt
    65401 attcaacaaa ataatcatag cactttccta aaaaaacgca agttattttt cttgatcgga
    65461 tagttgttgc tttactcgta aaaggcggcg tactagtttc ttttctaatc cagcaggaag
    65521 ggcaatcagt tctgctactg acaagacggt gtccaataac tgatattctt tgacaggttc
    65581 attcataata tgatagatgt ttgctaaacg ttcaatatat tcaaagcgag tatactctgt
    65641 tcgagcaatt agaaatttca ataaatcggt ggctttctcg tactcttgat ctgcgtaata
    65701 aacaagagat tgacgataca atttgatttc cagttcattg agggtagcag gtctgcgacg
    65761 ctcgttccac tcattaatag agactttacc ttgaacattt cccttgcagt cacggacaaa
    65821 aataatcgga atttcatttg gatccatttt tttatgtgtg aatttttcca ttatctacgc
    65881 tcccttcaaa ggtttggtat cttgagtata agggattttt gtttgaatta ctagcttttc
    65941 tccaaagtta gcatctgtcc acccattgca gtgaaaatcg ccgaaaaatc gttgatcggt
    66001 actgctcgat tttttacacc atagggatcg ttgacataaa tattttcttt gtcatatcca
    66061 gtgactacac aagcatgaac aagaggagtg actcttactt ctccattatt tgtggtccaa
    66121 gtcataaaat cagtttcatc tgggacttca aaattgatag tcacagaagt ccagacagga
    66181 tttcctttag atagtgcttt tttgatatca tcgagttgag catcggtttt tggaaaagtg
    66241 tgataatccg tttggacgat ttgctgagca agggaggcaa ctgggggaac atagacgacc
    66301 atagcccagt ctccgccact gatatcacca acaaatcctt cattaggatc gccatgagtc
    66361 ccatctgcat tgaaaacagg gacgtaatcc aattgctcag ctaactggtt tttagttgtt
    66421 tcataaccat aaaaagataa aagcatagaa agcgaagtga cttcacagcc attttctaaa
    66481 gaaggagaat caaactggct ctctaatgga acatctagta aaacttctgc tttctctttt
    66541 gtctttttcg ttttttgtgt tgaacttttt tgtgcagtgt tcattgtatg ttctggagaa
    66601 tggatatgta ggtaataact tgtaccgctt aataaaagag cagctgtgcc ccctagaaac
    66661 aatagttttt tgaacgtttt tttcttcatt tgaaatctcc cttttcagct gtttatcttt
    66721 cctattataa atgtattttt attggaaatg gaagtattat attttaatat gtaggaaata
    66781 attagttttt aaggaatatg ttttaatttt ttgaaaaaaa ttcttctaaa tacaacagct
    66841 gttttaattg tgaaaacgaa aacagtacgc tataatgcct gtaaggttga tttttaactg
    66901 taaataaaaa tcaatgagtt aaatctccaa agaaatagca gtggtaatgt ggagaaaagt
    66961 tccagcagtt taggaggatt ttgatgacgg aagaaatgat taatttagga gaacaatatg
    67021 catgcaaacc aattggtttt acaaaaacgg tcattggtga agttgtatca aaaatgacaa
    67081 actgcgccgt ggtcaaagtt gcccaatgtg ctgcagagga ccaagaatta ttagatgaaa
    67141 aagcaagcat ggttgttgca aaatatgata catttgaata aagaaaacaa ttggacgtgc
    67201 ggcgtgctgc aagtccaatt tctttgagaa ggtaaatcag tattcttttc ctattttctg
    67261 gagaagaaaa agcgaggcga gttgtcatgg taacattctt tacggttcta ttgtttttat
    67321 tcgttgttgt gatgttttta tttctttggc tggttcgaaa agaaattatt tatcggactg
    67381 tgcgaaatcg atgggtctac ttggtgatac ccttcttagt gtcactagtc atttggtata
    67441 cactcatcag tcatcctaca gcagatgaat tggcaaaagg gatcttgtca gcaatgattt
    67501 ttattagttt tttgttggac agtagaggaa tcacagaaga aggacttgtt ttgaatagct
    67561 ttgacaaaaa aggtgttcct ttttctgaga tcaataaaat tgtattatat cagccaaaag
    67621 gttctaaaat cgtaaaaatg aattttttcc gaaacggatg gcgaggaccg atgctgaaat
    67681 tttctgcatc attagaagaa ttagttccat ttttgtccca acgcttaaac gatgaggcag
    67741 agattgatat tatgattgat ccagaataaa aacagaggtt gcgacaagat gtttgtcaca
    67801 acctctgttt tttatttcaa ataaaattat ccaaatacgc ggaagcgatc ggcatcgttc
    67861 atgtattctt tttcctcagc cggtgtttct ggtgaaccga atactaattg cgaacgtagt
    67921 ttccagtttg aagggatatt ccattctttt gcaactgctt cgtcaataac tgggttgtaa
    67981 tgttgcaagt ttgcgcccaa tcctttatca actaatgcta cccaagtatt agctgttgcg
    68041 attccgtttg attgttctga ccaatctggg aagttgtctg catataattc aaattgttct
    68101 tgtagacctt ttaccacgtc agtatctttg aagaataata ctgtaccata accatttttg
    68161 aaaccagcta atttgttttg tgtatttggg aaagcttctg ctggagtcaa tgggcgaagt
    68221 gcttcttcag tgatttccca aagtttttca tgtgcatctc cgaaaaggat aactgcgcgt
    68281 gttgattgag cattgaaagc agttgggctt tctttaattg cttctttgat caaagttgtt
    68341 aattcttcat tagaaagtga aacattacgt cctagatgat agattgaacg gcggtttttc
    68401 aaagtgtcag taaaagttgt cataataaaa tttctccttt gatttgcgtt ttgcattttt
    68461 ttaattgatt acgaaatgaa gtatagcacc ttacaaaaag taagtaaaca gatatgctca
    68521 caaaaaataa gcgaagttca aaaaacaatt ttaataagaa aaatcgttat gtaaggattt
    68581 tcttagttat cgctttcatt gttgtgtttt aggaattttt gcttat
//
LOCUS       DACBYO010000004        68295 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.004, whole genome shotgun sequence.
ACCESSION   DACBYO010000004 DACBYO010000000
VERSION     DACBYO010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.004"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(38..1381)
                     /gene="vanS"
                     /locus_tag="IVD26_000214"
     CDS             complement(38..1381)
                     /gene="vanS"
                     /locus_tag="IVD26_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAP6078224.1"
                     /translation="MERKGIFIKVFSYTIIALLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAAFHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQAQSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            complement(1384..2043)
                     /locus_tag="IVD26_000215"
     CDS             complement(1384..2043)
                     /locus_tag="IVD26_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HAP6078225.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            complement(2256..2474)
                     /locus_tag="IVD26_000216"
     CDS             complement(2256..2474)
                     /locus_tag="IVD26_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078226.1"
                     /translation="MRQERPEGVHTGPACVKSHTARCIRKKEAAHFAEAWGVPNKQNE
                     NAAGGQVVDQNIRKGYSDPLLASIIGMF"
     gene            complement(2661..2807)
                     /locus_tag="IVD26_000217"
     CDS             complement(2661..2807)
                     /locus_tag="IVD26_000217"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078227.1"
                     /translation="MTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVSRHWITAG
                     LMRL"
     gene            complement(2986..3171)
                     /locus_tag="IVD26_000218"
     CDS             complement(2986..3171)
                     /locus_tag="IVD26_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP6078228.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            3316..3687
                     /locus_tag="IVD26_000219"
     CDS             3316..3687
                     /locus_tag="IVD26_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6078229.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            3945..4274
                     /locus_tag="IVD26_000220"
     CDS             3945..4274
                     /locus_tag="IVD26_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP6078230.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            4235..5563
                     /locus_tag="IVD26_000221"
     CDS             4235..5563
                     /locus_tag="IVD26_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP6078231.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            5560..5931
                     /locus_tag="IVD26_000222"
     CDS             5560..5931
                     /locus_tag="IVD26_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078232.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            6114..6350
                     /locus_tag="IVD26_000223"
     CDS             6114..6350
                     /locus_tag="IVD26_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6078233.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(6650..6853)
                     /locus_tag="IVD26_000224"
     CDS             complement(6650..6853)
                     /locus_tag="IVD26_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078234.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMLVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(6857..7801)
                     /locus_tag="IVD26_000225"
     CDS             complement(6857..7801)
                     /locus_tag="IVD26_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078235.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            complement(7802..11722)
                     /locus_tag="IVD26_000226"
     CDS             complement(7802..11722)
                     /locus_tag="IVD26_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HAP6078236.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKID
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            complement(11871..13952)
                     /gene="topB"
                     /locus_tag="IVD26_000227"
     CDS             complement(11871..13952)
                     /gene="topB"
                     /locus_tag="IVD26_000227"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP6078237.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            complement(13949..15178)
                     /locus_tag="IVD26_000228"
     CDS             complement(13949..15178)
                     /locus_tag="IVD26_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HAP6078238.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            complement(15168..15419)
                     /locus_tag="IVD26_000229"
     CDS             complement(15168..15419)
                     /locus_tag="IVD26_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HAP6078239.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            complement(15442..17433)
                     /locus_tag="IVD26_000230"
     CDS             complement(15442..17433)
                     /locus_tag="IVD26_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006060479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HAP6078240.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            complement(17465..19864)
                     /locus_tag="IVD26_000231"
     CDS             complement(17465..19864)
                     /locus_tag="IVD26_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HAP6078241.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            complement(19794..20216)
                     /locus_tag="IVD26_000232"
     CDS             complement(19794..20216)
                     /locus_tag="IVD26_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HAP6078242.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            complement(20230..20772)
                     /locus_tag="IVD26_000233"
     CDS             complement(20230..20772)
                     /locus_tag="IVD26_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HAP6078243.1"
                     /translation="MLISTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVE
                     RLASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTR
                     GNAEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFAR
                     QKTPGWDVWGNEVECDLILT"
     gene            complement(20803..21666)
                     /locus_tag="IVD26_000234"
     CDS             complement(20803..21666)
                     /locus_tag="IVD26_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078244.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            complement(21758..21973)
                     /locus_tag="IVD26_000235"
     CDS             complement(21758..21973)
                     /locus_tag="IVD26_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer protein"
                     /protein_id="HAP6078245.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            complement(22050..23858)
                     /locus_tag="IVD26_000236"
     CDS             complement(22050..23858)
                     /locus_tag="IVD26_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003819036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP6078246.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            complement(23855..24331)
                     /locus_tag="IVD26_000237"
     CDS             complement(23855..24331)
                     /locus_tag="IVD26_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HAP6078247.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            complement(24406..24618)
                     /locus_tag="IVD26_000238"
     CDS             complement(24406..24618)
                     /locus_tag="IVD26_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAP6078248.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            complement(24640..25839)
                     /locus_tag="IVD26_000239"
     CDS             complement(24640..25839)
                     /locus_tag="IVD26_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6078249.1"
                     /translation="MLFTSGPDRAFERLMQEKPGFDHYDGGGADAPEDCGTCRFYRPD
                     WKYQFCQFAECPYQPGKLTDYAAVKFTVKGANNAMAVFRVEKNKGYTVMSNHHLRNKN
                     LTLKAKGLLSQMLSLPEDWDYTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDA
                     KGKMADMVYTIYEQPVLENPVLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLS
                     KKEKIITDGQSTHSIPIPSPTPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEY
                     AYLIQDRSIDREQLDEIVDLMLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRF
                     VLDCLRENTTKVRNIKQYLRAMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYS
                     CGEGESL"
     gene            complement(26096..26617)
                     /locus_tag="IVD26_000240"
                     /pseudo
     CDS             complement(26096..26617)
                     /locus_tag="IVD26_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
     gene            complement(26633..27331)
                     /locus_tag="IVD26_000241"
     CDS             complement(26633..27331)
                     /locus_tag="IVD26_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP6078250.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(27288..28949)
                     /locus_tag="IVD26_000242"
     CDS             complement(27288..28949)
                     /locus_tag="IVD26_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAP6078251.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            29167..30567
                     /locus_tag="IVD26_000243"
     CDS             29167..30567
                     /locus_tag="IVD26_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAP6078252.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(30819..31898)
                     /locus_tag="IVD26_000244"
     CDS             complement(30819..31898)
                     /locus_tag="IVD26_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6078253.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(31984..32943)
                     /locus_tag="IVD26_000245"
     CDS             complement(31984..32943)
                     /locus_tag="IVD26_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAP6078254.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(32955..34477)
                     /locus_tag="IVD26_000246"
                     /pseudo
     CDS             complement(32955..34477)
                     /locus_tag="IVD26_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
     gene            complement(34487..35050)
                     /locus_tag="IVD26_000247"
     CDS             complement(34487..35050)
                     /locus_tag="IVD26_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAP6078255.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(35056..35919)
                     /locus_tag="IVD26_000248"
     CDS             complement(35056..35919)
                     /locus_tag="IVD26_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6078256.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(35933..36829)
                     /locus_tag="IVD26_000249"
     CDS             complement(35933..36829)
                     /locus_tag="IVD26_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6078257.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(37004..38275)
                     /locus_tag="IVD26_000250"
     CDS             complement(37004..38275)
                     /locus_tag="IVD26_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6078258.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(38265..39782)
                     /locus_tag="IVD26_000251"
     CDS             complement(38265..39782)
                     /locus_tag="IVD26_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAP6078259.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            39980..40870
                     /locus_tag="IVD26_000252"
     CDS             39980..40870
                     /locus_tag="IVD26_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAP6078260.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(40943..41767)
                     /gene="nadE"
                     /locus_tag="IVD26_000253"
     CDS             complement(40943..41767)
                     /gene="nadE"
                     /locus_tag="IVD26_000253"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAP6078261.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(41779..43251)
                     /locus_tag="IVD26_000254"
     CDS             complement(41779..43251)
                     /locus_tag="IVD26_000254"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAP6078262.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(43888..44250)
                     /locus_tag="IVD26_000255"
     CDS             complement(43888..44250)
                     /locus_tag="IVD26_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAP6078263.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            44473..45225
                     /locus_tag="IVD26_000256"
     CDS             44473..45225
                     /locus_tag="IVD26_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP6078264.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(45365..46288)
                     /locus_tag="IVD26_000257"
     CDS             complement(45365..46288)
                     /locus_tag="IVD26_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP6078265.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(46303..46575)
                     /locus_tag="IVD26_000258"
     CDS             complement(46303..46575)
                     /locus_tag="IVD26_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078266.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            complement(47045..48670)
                     /gene="groL"
                     /locus_tag="IVD26_000259"
     CDS             complement(47045..48670)
                     /gene="groL"
                     /locus_tag="IVD26_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAP6078267.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(48721..49005)
                     /locus_tag="IVD26_000260"
     CDS             complement(48721..49005)
                     /locus_tag="IVD26_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAP6078268.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            49230..49892
                     /locus_tag="IVD26_000261"
     CDS             49230..49892
                     /locus_tag="IVD26_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP6078269.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(49968..51260)
                     /locus_tag="IVD26_000262"
     CDS             complement(49968..51260)
                     /locus_tag="IVD26_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6078270.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            51430..52059
                     /locus_tag="IVD26_000263"
     CDS             51430..52059
                     /locus_tag="IVD26_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HAP6078271.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(52162..52971)
                     /locus_tag="IVD26_000264"
     CDS             complement(52162..52971)
                     /locus_tag="IVD26_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP6078272.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(53026..53895)
                     /locus_tag="IVD26_000265"
     CDS             complement(53026..53895)
                     /locus_tag="IVD26_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078273.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(53896..55212)
                     /locus_tag="IVD26_000266"
     CDS             complement(53896..55212)
                     /locus_tag="IVD26_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078274.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(55209..57044)
                     /gene="walK"
                     /locus_tag="IVD26_000267"
     CDS             complement(55209..57044)
                     /gene="walK"
                     /locus_tag="IVD26_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAP6078275.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(57049..57753)
                     /locus_tag="IVD26_000268"
     CDS             complement(57049..57753)
                     /locus_tag="IVD26_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6078276.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(57943..58803)
                     /locus_tag="IVD26_000269"
     CDS             complement(57943..58803)
                     /locus_tag="IVD26_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP6078277.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(58790..59359)
                     /locus_tag="IVD26_000270"
     CDS             complement(58790..59359)
                     /locus_tag="IVD26_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAP6078278.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            59740..59812
                     /locus_tag="IVD26_000271"
     tRNA            59740..59812
                     /locus_tag="IVD26_000271"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59773..59775,aa:Lys,seq:ctt)
     gene            complement(60308..60694)
                     /locus_tag="IVD26_000272"
     CDS             complement(60308..60694)
                     /locus_tag="IVD26_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAP6078279.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(60691..61212)
                     /locus_tag="IVD26_000273"
     CDS             complement(60691..61212)
                     /locus_tag="IVD26_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAP6078280.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(61214..62248)
                     /gene="sppA"
                     /locus_tag="IVD26_000274"
     CDS             complement(61214..62248)
                     /gene="sppA"
                     /locus_tag="IVD26_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAP6078281.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(62281..63696)
                     /locus_tag="IVD26_000275"
     CDS             complement(62281..63696)
                     /locus_tag="IVD26_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HAP6078282.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(63665..65818)
                     /locus_tag="IVD26_000276"
     CDS             complement(63665..65818)
                     /locus_tag="IVD26_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HAP6078283.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            66076..66312
                     /locus_tag="IVD26_000277"
     CDS             66076..66312
                     /locus_tag="IVD26_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAP6078284.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            66331..66546
                     /locus_tag="IVD26_000278"
     CDS             66331..66546
                     /locus_tag="IVD26_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAP6078285.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(67249..68001)
                     /locus_tag="IVD26_000279"
     CDS             complement(67249..68001)
                     /locus_tag="IVD26_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6078286.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(68016..>68295)
                     /locus_tag="IVD26_000280"
     CDS             complement(68016..>68295)
                     /locus_tag="IVD26_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP6078287.1"
                     /translation="DNAIEASIESQDRELSLAIYRDDKQIEISISNSCREILLSIDTL
                     MKKGITTKKGHQGLGLSSIEEINKKNPNMFVNYQNDPYQFTTQVILLF"
BASE COUNT        18048 a        15787 c        13909 g        20551 t
ORIGIN      
        1 tatacctgtc ggtcaaaatc atttaagttt taaatattta caatgttgat gtgagcggta
       61 aatccagcca gaacaaaacg ccatccgagg tgttttccag cgcatactgg aggctcatgg
      121 catccagcgt tttttgtacg atggcaagtc ctaaaccgct tcgcccactt tttctgcttt
      181 gcgcctgatc aatgcgatag aatggggtga acagccttgg aagcgcagta tcatcaatgt
      241 gaacgcccat gttcaaaaca aaaaggcggc atttttcagc accaggctca ctccatatcc
      301 gtacctcgcc tccctgcggc gtgttctgaa ctgcattcaa tatgacattg gatagtgcct
      361 tttggagcag cctcggatcg gacaggacaa tttgcccggc tggaatatct gtgacgaacc
      421 gctggttgtt tgcctctgcc aaggtttgaa aatcgggcag caactcggca accgtgcgcc
      481 ctatgtccaa cggttcagct atgggtacga ttctcccatc attcaggctg acaagctcca
      541 gtatttcgga aatgattttg ccctgcctat ccatcatttt gatgcattcg cgcagatact
      601 tagaatgatc tttgtagtca ccgatatttt caagcattcc ctccaacaga acgcttgtag
      661 ccgcgatggg cgtttttagc tcatgaaaag ctgccgcaaa gaaatatcgc tgtgtttcct
      721 ccaactcatg ttcccttgcg atttcatcct ccagccttgc gatggtttct ttcagcctga
      781 catacatgga atgcatatca tgagccagtg cgccaagctc atcctttcgc tccagcggcg
      841 gcggtacatc tttcaggttt gccattttat tcgcactgtc cgctaaggct ttgatcggcg
      901 ttgtcatttg ccgcgcaaag atatacgcgc ataaaaggct gaatacaacc attatcgcaa
      961 tcataacaat tccccgaatt gtcagccctt gataaagcaa tcccacacct gccttgcttt
     1021 gagcaacaat cgaaatatta tcatctctat gtaccacata aagaaagtcg ggtctaaaac
     1081 tatttgatgt attggcattt ggtgtggcat agagtacgct tccctcttta tcttcaatat
     1141 aaaactcaaa ggattggtta ttgtagtgaa acagccctgc cacctcttga atatcaagcc
     1201 tatcgctatt ctgaatcagt tccaccaatg gctgatagga ttttactgtt tgctgtaatt
     1261 ccatcactct gaaataagac acaaattgct gtgcaaacag tgttgctgtt acaccgacaa
     1321 gcagtagcag ggcaatgatc gtataggaaa aaaccttaat gaaaatccct tttctttcca
     1381 ttattatgat tcctccaatc ggtatcctac accgcgaatg gttttgatga tattttccgg
     1441 cagcttggcc cgcaaatttt tgatatgagt gtggactgtg ctgccatcac cctcaaagtc
     1501 atatccccat atacgtgaca aaatgatttc atgcgttaag gttctgcctt tgttctgcac
     1561 cagcagcaaa aggatttcaa attcttttcg tgtcaggggc agctctgtac cgtcacaaag
     1621 taccgtgaaa tcctccggca gaagtgtcag cctgccgaca cggatttcct ttgccagcgc
     1681 accgctgcgc cgcagcaggg cttccacccg ctttagtaaa atctgcatct tgaatggctt
     1741 tgttacatag tcgtctgcct ctgcatcaaa cgcccggatt tggttttcgt catccgacag
     1801 ggctgtcatc atcagaatgg gagtatcatt tttcgcacga aattcacgca aaagttcatg
     1861 cccgttcata ccgggcagca taatatcaag aataaccagt tgataagtgt tttcgtaaaa
     1921 cttggtgtat gcctcatttc catctgtgca ggcatccacc tgatatcctg cctcagccag
     1981 aaacgccctt actgtattac agatatgatc atcatcctcg acaagtagaa ttcgtatcga
     2041 cataaaaatc cctccatttt aagaagataa cataacagtc tgtagtttcc ctgtagtttc
     2101 aaagcgattt cttttcggat tttaatcatc cgtcattggg atactcgctt cttttcatgg
     2161 tgtatgtatc tatattattg gtttaaacga attaaatcaa gataataata attaacacct
     2221 tcttaatgtt tgggatgttt cgattacagc ggttgtcaaa acatcccgat aatactggca
     2281 agcaatggat cagaatatcc tttacggata ttctgatcca ccacttgccc gcctgcggcg
     2341 ttctcgtttt gcttgttggg gacaccccaa gcctcagcaa aatgcgcggc ctcttttttg
     2401 cgaatgcacc ttgcggtatg gcttttcaca caggcagggc ctgtgtgtac tccctccggt
     2461 cgctcttgcc gcactccgcg cagcagattc agtcctaata ccgttcaaga cagtagaaaa
     2521 tcagcaagtc tatattcctc atatcttcat catccgtgtc cttgcagtta caggaaatgt
     2581 aataatcgcc aaatgtaaat cccagaatat tttcctcaaa aagccgtacc tccccggtat
     2641 taaaatcaat caccccatac tcaaaggcgc attagaccag cagttatcca atgtctggag
     2701 acttcaccat aaagaatcca gatgccggcc ttttcaattc taccatatac ggctgataca
     2761 gcagcagctt cctcgtcttt gtttcgggca ttttccattt ctgtcatgat aaagtttcgc
     2821 ttcttcatac atccatgtgt aaatcttttc tttctgtttc agatgagaat actttttatc
     2881 ggtctggagc agcctgccat ctatcatctt atagtttttc cgtgacaaaa taccatgctt
     2941 tctctctctt caaaaccata tccaaaatgc gccggtttca ttatactatt cagtaaccgc
     3001 ctttcctttc tttgtacgcc tgtcaatcgg cttttccgca gttttgggaa tgagccagat
     3061 cgtcgccatc tttacagcgc cggggatgcg tcccgcagca caatagtagt ttatccatcg
     3121 tgggggcaca ccccatttct cgcctgcctc tttcaacgtc atgtagtcca tagtacacct
     3181 ccacagggta cattataatt cttttgctcg aagaataaaa gaaacaaaat gtgaaatata
     3241 aactttaaga aaggtgcata taccaacatt ccacgggcag agtatgaaat atacaatgta
     3301 agtgggaggt gcgatatggc gaatattgaa gattgtcccg gctttgaaac tttcggcgcg
     3361 gatgtgaaag cggcccggca agcaaagcgc gtttcgcgca aagcaatggc agagaaaata
     3421 aatattgact ggcgctatct tgccaacatc gaaaacgacg gggccattcc cagtctgccg
     3481 gttgtcatac agcttattaa agcctgcggg cttcctgtgg aacgctactt taacccggag
     3541 atcatgcggg aggaaagcga actgcggcaa agggtcagcc acaagctgaa actctgcccc
     3601 gaagaatacc tgccgatcat cgagggcgcg attgacagcg ccatactaat tgaaaagccg
     3661 aagaagaatg aaacggagga tgtgtaactg gcatcctctg ttttactttt agcgggagct
     3721 gcacagcgta gcttctattt ttttgcactt ttttctttcc agagggctat tttgcgggta
     3781 gtttggggct ttggaaacgt cttgttagtg gagaaacagt aacgtagcaa gcatagggag
     3841 tgtagccact cccggaaaaa cggcctgccc cgtccctgcc gggccgcgtc cgttttgctt
     3901 gttggggaaa tccccaaacc cctgaatgga aaggacggtg aagcatggca aacagaaagc
     3961 gaaaaatcgt gctgcgcgtc cctgtgacgc cggaggaacg ggctatgatt gaacagaaaa
     4021 tggcgctgct gcatacgaag aacttttcag cctacgcccg gaagatgctc attgacggct
     4081 atatcgtcaa catggacacc agcgacatcc gggcgcagac cgccgagata cagaagatcg
     4141 gcgtcaacgt caatcagatt gcaaagaggc tgaacggtat ggggccggtg tacgcacagg
     4201 acatcgagga tataaagggg gcgctggcgc agatatggca gttacaaaga tacatcctat
     4261 caagtcaacg ctgaaaaaag cccttgacta catcgagaac ccggacaaaa ctgacggcaa
     4321 gctgctggtg gcctcctttg cctgctctta tgaaacagcg gacattgaat ttgaaatgct
     4381 gctggcgcag gcataccaaa agggcaataa tctgggccac cacctgatac aatcctttgc
     4441 ccccggcgaa gccacgccgg aacaggccca tgagatcggg aagcagcttg ccgaggaagt
     4501 gctgcaaggg aaatatccct atgtgctgac tacccatatt gataagggcc acgtccacaa
     4561 tcacattatt ttctgtgccg tggatatggt aaatcagcgc aagtacattt ccaacaaaca
     4621 gagctatgcc tatatccggc gcaccagcga caggctgtgc aaggaaaacg gattgtccgt
     4681 ggtgaagccc ggccagagta agggcaagag ctatgccgag tgggacgccc agcggaaagg
     4741 gacgagctgg aaagcgaagc tcaaagcagc cattgacgcc gctatcccgc aggcaaaaga
     4801 ttttgatgat ttcctgcggc tcatgcaggc gcaaggctat gagatcaagc cgggaaagtt
     4861 tatttctttc cgcgctcccg gacaggaacg ctttacccgc tgcaagacat tgggggaagc
     4921 ctacaccgag gaagccatca aagagcgtat caaaggccgc gttatcacca gagcgcccaa
     4981 agagcgcaag gggatttctt tgcggattga tctggaaaac aacattaagg cccagcagtc
     5041 ggcaggctat gagaggtggg cgaagctcca caatttgaag caggccgcaa agactttgaa
     5101 tttcctgact gaacatggga tagacaccta cccggatttg gaaagcaaag tggccgagat
     5161 caccgccgcc agcgacgagg ccgccgctac cctcaaagct atggaacacc ggcttgcgga
     5221 tatggcggtg ctgataaaga atatttctac ctacaagcag ctctggcccg tggctatgga
     5281 ataccgcaat gcagcggata aggcaaaatt ccggcgtgag catgaaagca cgttgatttt
     5341 gtatgaagct gcggcaaagg ccctaaaggg acagggtgtg aaaaagctcc ccgatctgta
     5401 cgccctgaaa gccgagtaca agcgattggc cgaggaaaag gaacggctgt atgagaagta
     5461 cggcgaagcg aaaaagcaga tgcaggaata cggcatcatc aagcagaatg tggacggcat
     5521 tttgcgtatg acgccgggaa aggaatggac gcaagagcta tgagtattcc acgaatgaat
     5581 taccctcaat atcgcaaggc ccggaagctg acgcatgagt gctgcaacta ttgtgacggc
     5641 aactgcctgt tgctggacga cggcgaagaa tgtatttgcg tacagagcat ttcctattcg
     5701 cttctgtgcc gctggtttaa ggccgctgtc ctcccgctgg atgcggccct gtatgccgag
     5761 atcaccaaag accgggacga agtgaaacgc tgctgtgagt gcggggccac gttcacgccg
     5821 aagtctaacc gggccaaata ctgcgcggcc tgctccaaac ggatgcgccg ccgcaaagag
     5881 gccgagcgcc agcggaaaag atactggaaa cctacgcact tagagctgta aaagccctta
     5941 tatttcaagg cttttccggc atggtcagcg gggtatgtgg gtgttttatc ctatccccgc
     6001 cgaagtgctg ttctaaatgc gtagaattta ccagcagaaa agcgccgttt tctctggttc
     6061 catgcttccg aatatggtat catagaaaaa atcagtctga cgggggtatc aggatggacg
     6121 gacaagaaaa gctgctggac tatgaaacga tcaaagccgc cgttgccggt gagaggtggg
     6181 ccacggaaaa agtgttggcc cattatgctg actacatcaa cgagctttcc acggtggaga
     6241 tcagacaggc aaacggcaaa aagaagaaag tcattgacga agatatacgg cagcgcattt
     6301 ccctgaaact gctggaagca ttgccgagct tcccgctgga acagagatag acggcaagag
     6361 ggctgcaccc tcttacgccg ctttgcggct atcacctgca cacccctgaa acagatacac
     6421 ccgctgcgcg gctatatctg tttcaggggt ctaattatag ctgcaaccta cgcatttaag
     6481 ggattgaaaa ccgcccgctg caaggcttct cccgcatgtt tgcaggggca agcgaatact
     6541 tcatcctatc cccgacaata ccgggttcta aatgcgtagg aataggcaaa aagaaaagac
     6601 gccggacgca agcgaccaca tggccgccgc gcccggcgtc tgctgttcgt tattcgtctg
     6661 tgaagtggaa cttctggccg tcatagtcgg catccgtcat gcgttccagc ttggaaaggg
     6721 tctgctgggc ctgcgcccgc atatccccat ccataaccag catgacggcg gtgagcctgt
     6781 ttatcgttct gcgccggtct gcattgtggt acatacagat caggttttct tcctccacgg
     6841 taaagtgcat cattccttat acctccaatt cattcttttt ggttctggcc gccgcctttt
     6901 ttgggctggc ggcctgtttg ctgtcggata gctgcttgcg gatagagggc cggggcctgc
     6961 gaatactcac atcccggcgc tcgtcccggt taatcacggc atacacgcca tgcctgcctt
     7021 tcatcccggt aaaacacagg gatttatagg gcagcatggc aaagagccgg tcattatcct
     7081 tggtggaagc aatcgccgca aagtgcgggg agatctccac catgaaatgc gttttattgg
     7141 ggctgttagg cgcggacaga tctttcaggc tgtccacaat acgccgggcc tcggtttcaa
     7201 tccggctgtc atgcaaagcg gtgacgtgga ctttgaaatc gccggggacg gcccgccccc
     7261 ggctgtgctg ctccgtccgt agcgcctcct gcagcacagc cgggtcatgg ggctgggcct
     7321 catagtacaa aaagtttccc aatacccggt cagggcttcc gtcaaaacgc tggctctccg
     7381 ggatgtcacg ggtgccatgc tcataaaaga gccggttcac actcaccggc tgggcggttt
     7441 caatgacgtg ccggaaatgc tgcggatagt ccagctcata gagattgccc cggatagtgc
     7501 cgccctgtgt gccggtcagc tccaccgcgt aggccagtat cttgtcacgg gtctgctccc
     7561 cgtaaaattt ccatgtgttg tactgtcggg tgtctttcag gaaaacatca cgttcccgga
     7621 aacagtacgt cccggagggc cgggacatcc agagcagggt cttgtctgcg gcctgatcgc
     7681 tggcggcatc ccgcctgata atgtctttgt caatgccaaa gtcactttga taaaacgcgg
     7741 tgttctgccg catgatctgt tccagcgcgg ccagaacgtc cacattttca aacttctgca
     7801 tttactctac ctccaatccc tttgattttt cccgcgccgg tggctgcttg gcctgttcgg
     7861 tcttggccgc gttgagctgc gcccggatag agggcttttc tttctccctg cgggccgcaa
     7921 gctgtaaggc gctgggcttt tcgccggaaa ggggctggat gcacttgata cggtcagcga
     7981 cgcggattgt ggtgtcgttt aactgccgct gccatgcccc ggccttgggc gaccagcgga
     8041 aaccgttgct tttcagctcg tcgcgtacag cagcatccgg cttcccctca aagaagattt
     8101 gcaggcggtt ggccacccgg ttgatctcca cagtgccgcc gtcaaactcc catcccacat
     8161 aggccgcctc cttttggcgg gtcaattcct caatgcggcc ctttaaccgg cgtatctcgg
     8221 cgttattgtt ggagagctgc caggactgga acggtttttt ctcatagtgc cagcccgacg
     8281 ccatatccgc tttcaggttt tcaatgcctc tttcggtcag atgggggcat ccgtccagcg
     8341 tcccatgctt gcggtagtag gcattgacgg ccttcatcaa ctcctgcgac gcttccagct
     8401 tttccagttt cttttccagc ttggaaacgg cctgcggatc gtcggcgctg ataccaccca
     8461 tgccggtgct gcggattttg tcaagcaagc cctgaatgta ctgaaattcc tccatgttgc
     8521 ggtcactggc ggcgttctgc ttttctttcg cccgtaccgg gaaattggac ggcccggcaa
     8581 tcaggacaga ggggacgcgg gcggtaatct catagccctt attcatgttc tcggccagct
     8641 tgcgggcgta ggtgtcaagg aggctgtcta tcttttcgtg atactctggc tccacacgct
     8701 ttttctggcg ctccgcaatt tccacggcct gatcgacata gtgccggtat tccgccgtgg
     8761 cgctgccggg ccggtagtca gaaaagctca tggcttcctt ggcgcggcgg gcggctccct
     8821 cattgatggg ataatagcgg acagccgttt gcgggggcgc agcctccggg ggttcctcct
     8881 gtgtctggcc ggaagcaact gccacatcct caaaagatag ctgttcgggt tcctccggct
     8941 gcggttcggg cggcgtattg ttgataatgc cgtcaatcat gttttcgttc tgctccgtag
     9001 acagttcggc ggtacgcagg ggattttccc gcaaaaactc cggcacttcc atatagccga
     9061 agctgtctac atagtgggcg gtgtcctgtc cattctggtg cagcaccacc acgtcggaaa
     9121 cggaaaggct gtgtccccta aaatctgccg ggtggtcgat gttgaatgtg cggtaaatat
     9181 cctccaaaga cgtgctttta tccagcggtg ccgtataaac aaggtcatag ttggcactgt
     9241 ccacggccag ccctgcggcc tgtaaacgct cgtatggctc aaaccgatag tcgcgggttt
     9301 cctccccgcc tcgaagctgg tagatggaaa aggtgtcctg ttggggtgct tcatagccag
     9361 ccgccgcgta ttcctccacg gtcataccgg ctgcggcggc ctcctgcgcg atctcggcct
     9421 gtacctgtgc tttgtagtcc tgcaagctct ggtcgaagtc agccagtttc ggcggctccg
     9481 gcaactgata ctggccctga ttgagcatgg ggcggcactc ctgcacataa gagagaagcg
     9541 cccccaaata ggccgtttcc tccggcgtca gggtttcccc ggactgtaag cggccctgcg
     9601 ccgtctgttc catttgggca aggctgcaat gcagcttcat ataggggaca aactcgccta
     9661 acagcatatc ccgatgggcc ttgtcctgct cccagccctc tatgccggtt gtagcgatta
     9721 catgcttttt ccagttttcg tcctgcgcgt aaaattggtg gtagctctgg atatgttcga
     9781 tcagggaacc gtccctatct ccaaaatcct gccgcccctc gtagctgtcc ggctcgccct
     9841 gaaagataca gtcaatgcgg aacgcggttt tgtcatagcc tgcctctgcc ggatatgctg
     9901 catccagacg ggcaaacagc gcgtcggcct catgcaacgg catttgctgg ccgtccttta
     9961 gctgggggct ttcgctccat agcacagtca caagcggctc ggctgccgga tcaagggccg
    10021 gggcctgttc ttcctcggcc tgcgccgggg ccgctgcctc cggggtaacg tcaaccgtga
    10081 cggcctcctg ttcctgccgg gcctcgcgct cctgctgaag ctgggcaaaa tggccgtcga
    10141 tctcggttat caattcgctg gccgtggccc ggatggtttc aagggaggct ttcagctcgg
    10201 ataactccct gccgctgctc caatcggcca catagccaaa agaatagtcc gacgtgtcca
    10261 gcccgtaata ctggcagacg gtataggcca cgctttcggc ctgtacctcg cgggtgctgc
    10321 ggtctggccg ggccgcctgt tcctcggcgg gggcctcccg gtcaatggcg tggagcttgg
    10381 catgggcaat ctcatggatg gcggtcttta gggtctgcaa ttcgctcatg ccctcgttga
    10441 tggcaatgcg ctgttttgcg tagaagcagc ggcccttggc cccgtctgaa atcggctcaa
    10501 tgcttatggg atagggtgat gtccgttcca gcgcggcaaa gaaatcctga tactgctgca
    10561 cgtcgccggt aagttcactg atatagggca tgggaaaatc cttgccctcg gtctggctga
    10621 tgtcaaagac tgtcaccacc ttaaaggccg gaaccgtcac ttcctgttct tcggtcacgg
    10681 gcttgccgtc cgcgccgatc acgggctgct gggtggccgg gtcgattttc tccatctgct
    10741 gcttaacctt gaacggggcc ggggccagta tcttaatgcc tttctcgccc cgcttcacat
    10801 ggcggtcaaa ttcatcctgc cacctgttat agcccgccac aatcgaaccg ccctgcatgg
    10861 cgatcagcag cgtattgttc agactgtaat cgtgcatctt ggacatagcg gataagtaag
    10921 ccatatagcg gctactttca aaaagctcct gtacgccggt ttccagacgg tcagtaatca
    10981 ctttcatgcg ttctttgctg ttcatgccgt ccagcatgat cgggataacc gggggcggcg
    11041 ctttgtcggg gctttcggat gcctccggct gctgggcctg cggttcctcc cggtcagctt
    11101 ccggctgggg gtagtgcatc acccggtatt cctccggcac cggctggccc tcatggacgc
    11161 gctgccattc gtcgccgctt ctcaccagat agccgtactg ggtaaaaacg ccttgttcct
    11221 gctgggcaat gtggcgtcca aactgcgccg tatcaatccc ggctttccat tcctccggca
    11281 tatccaccat gccggaacgg ttcaggtagt agtcgcccaa ctgtccatcc cccctaacgt
    11341 cgggaagatg cacatagtaa tccacatttt cggtgtagtc gatgatctgg ccgatattct
    11401 caaagccgcc acggggattt tgcagggcgg cgttcagctc tgcgatctcg gcggcgtcaa
    11461 gctggcccag ccgggcggca aggaaattca gctcgtccac gtcggcggcc agcaccatgt
    11521 catagggaat ggcaaggtgt ctgtcctccg ggcaggaata cccgttgata aaaaaatcct
    11581 gcggattgtc ggcagtaatg ccaacatccc gcagggcggc ttgcagcgtt tcggttgtgg
    11641 tgggcaaatc cagccagacg ccttgtttgc cctgttccaa aaactgccgg ttatggactt
    11701 ggatagaaaa tacttcgttc acgcggtcac tcctttctct gttctgtttc aaaaaatagg
    11761 gggttgggga cttccccaac aagcaaaaat ccccggcccg gcagggacgc ggccggggga
    11821 ttttaccggg agtgtagcca cactccctat gcttgctgtg ttactgtcct ttagctcctg
    11881 tgttcaatgc ggtagttgac gtacttgccc ccggtatcag ccaaaagcac cgtcccgtcg
    11941 taggttttgc cggtctttac ggaatagagg ccctttacct tgactttgcc ggttttgagc
    12001 agcgcagcgg cgatcttcgg ggtgaacgct ttcttgcgtt cctcaaaaaa tcggtcattc
    12061 ttccacatga cgaactggca ggcccggttt ccgcagtagt agtttttctt gccctcatag
    12121 acagcctcac cacagcgggg acacgtcccg ataggaacac gctcggcctg aaacaatttc
    12181 tgcttttcct cactgataca ggaataggtc tgcaccagct cccgcgcctg cgtctcgatg
    12241 ccgtccataa attcgtcagg atcggcctgc cccttggcga tctcggtcag ccggttttcc
    12301 cattcggcag taagctgggg agaagtaagc gcctccggca gcaccacagc cagattgatg
    12361 ccgtccttgg tgggaatgag ctgcttgcct tttctctgga caaagcccat ctgcaccagc
    12421 ttttccagaa tggcggcgcg ggtggccggt gtgcctaatc ccttgcgctc ggcatcctcc
    12481 ggcatatcct cggccccggc ccgttccata gcggacaaaa gcgtatcttc ggtgtagggc
    12541 ttgggcggcg tggtgaaatg ctcggtgaca gaggcggcca cgtctgcaaa ggtctggccc
    12601 tcgcaaagct ccggcagctc ccgcaccgcc tcggcgtcct cgtcggcgtc ggtctttaag
    12661 gaagaacgga accggcgttc aatctctttc cagccggggg aaaggacggt cttgcccttg
    12721 gcggtaaact cctgcccggc acaggtaaat gtggcggtga cggcctcata gatatgcggc
    12781 ccggccacgg cacataagag cttgcagcag atcagggaca gcagcttttt ttcactctcg
    12841 gccagagtgc caaagccctg cttcacaaat tcagcggtgg ggataatggc gtggtggtcg
    12901 gacacctttt tgctgttcag gatgcggtca aactgcgggg aaaggttcag gcccttggca
    12961 aacggcacca gctcccacag gccggacaca aggctttcca cggcgggcag catatcgtcg
    13021 gtaagatatt gactatccgt tctcggatag gtcagcagct tctttagata cagtgcctgg
    13081 gcatagtcaa gggtctgctt ggcggtatag ccgaaaagcc ggttagcctc ccgctgcaag
    13141 gtggtaaggt catagagctt gggcggctgt tccgtctttt tctcccgcgt cacggaaacg
    13201 caaacggcct gcgcttttgc acaagccgcc ttgacggtgt ttgcctcggc agcgtcggaa
    13261 aagcggctgc ttaccgcgtc cgcgccgccc gccgtgatat ggacgatgtg atatttctct
    13321 ttcttgaaat cggtaatctt ggcgtccctg tccaccagca tttttaaggt cggcgtctgg
    13381 acgcggccca cagtcaggtt cttgtggtac aggacggaaa aaagccgggt ggcgttaatg
    13441 ccgatcagcc agtcggcctt ggcccggcac agggccgatt gatacagcgg atcatagtcg
    13501 ccgcccggtt tcaggtgggc aaagccgtcc ttaatagcac tgtcctccat agaggaaatc
    13561 caaaggcgct caaagggctt ttggcatccc gccatctggt agacgaaacg gaaaatcaat
    13621 tccccctcgc gcccggcgtc ggtggcgcac acaaggccgg tcacgtcggg gcgctgcatc
    13681 agcgaacaga gaacgtcaaa ctgctgtttc ttgtcgtcgg ggacgatgta ctgccatgtt
    13741 tccgggagaa tgggcaaatc ctcatagcgc cattttttga aacgctcgtc atagcgtccg
    13801 gcgtcggcaa aggacaccag atgtccgatg caccagctca ccagatagcc gttcccctcc
    13861 aaatagccgt cgtgtttctc cgtggccccg atcacgcccg caatgctgcg ggccacgctg
    13921 ggtttttccg cgattacaag tttatatgtc attcctcgtc ctcctgttca ctcacaaaat
    13981 cagcttccgg gtcaaactcg gtttcgggtt cctcgtcctc caaatcctcg tcctccccaa
    14041 aatcatactc gcccaaatcg tcgctgccgg tggtttcagc cttgggcttt ttgaacttga
    14101 aatagtaaag ggccgcaccg ccgcccgcca gcgccaccag caggaacacg atcaggccgc
    14161 ccgcgccgcc cttgggttct tcctccgggg cttcgggttc ctccggctgg ggttcctgcg
    14221 gctccgggcc gctgcactcg gtcaggttgg ttttacatac cgggcaattc gtgttcacag
    14281 ccccggcctt gcatttcgtg gtacaggagc agacagcagc gggggtgacg gtttccccgt
    14341 cctccatcag cgtcagcaga tcggcttcat ccacctgatt taagaaatgg acagtttctt
    14401 ttccctcgtc gtcccggtca ataatcagat aaaacacatt gccgtttttg gtttccacgg
    14461 tgataaactg cttgccattt ttcgcggcgc tgccgatgtc gtcaatcagt gacaggttcc
    14521 cgtccgggga cagggcggcg ctggccccgc cgccattgaa cagttccagc agagaagcaa
    14581 tttcctccgg gtcaatggag agggaaaaac cgccctcgcc ggtagccgct acttcctttt
    14641 cgctgacggt catatagtcg gaatggacat agccgatgcg ctccggcaag agaattttaa
    14701 tccagtcgcc gtctgtgccg actacctcaa ccgtcgtccc attgggaagc tgggtgaacg
    14761 cggtcttgtc aagccccgcg ccggtgcgga cattcagcct gccgccgttg gtggtgacgg
    14821 tgccggtctg ttcaggttct tttttgtcgg tgccggtggt gatctggatg ccgtcgtccg
    14881 tggcggcaat gctcaccttg gaaccgaaca gcgcggaaaa caggtcggtg atgtccttgc
    14941 cggtcagagg gccggtatct ttttcggcct cggtttctgt cccgtccgtg gcggtgccgg
    15001 tttcgtctgt ttcaggctcc aaaccgcccg tagcgggttc ggttgtagcc tccggcagcg
    15061 gggccggtgc cgggtcattg ccgcctgcaa gggcggtaac gggaaaggcc gtgacgcaga
    15121 gcatcacggc cagaagtgcg gggagaatac gggaaatccg tctggtctta ttcttcatgg
    15181 gcattgtcct cctgttcatg gtaaggggtt gcggcagggg cggcctgcat tgcgccgctg
    15241 cgtaagaacg cggcaaattc ctccggcttc atgttcatgc cgcgcacaag ctggatgatc
    15301 tgcaaattct cctgttcggt tttctgcgtt tccagctccc gaagctgttt ctgaaactcc
    15361 gcgatcttag acttggtttt ctggatgtcc ttttcgatgc ggtcaagttt ggttgccata
    15421 attgaaagct cctttctggc gttaaggtaa acgcccgtaa ctgtaaaaat gggattgcca
    15481 gtagtttgaa gtaaggttcg tgtaggaaat cgggttcccg caatgcagca tcacattgtt
    15541 gcccacatac aggccgacgt gggacacgcc gggggtgtcg taggttccct tgaaaaatac
    15601 aaggtcgccg ggcttggcct gcgaactgga aacaggggtg cagatgttat ataggccctg
    15661 cgcccccagc cgtcccacgt tccatccact atgattgatt acccacgaaa tgaagccgct
    15721 gcaatcaaag ctggtgctgg gagagctgcc gccccacaca tagggataac cgatatattt
    15781 ttccgcctct ttgagcatgg cggcaaaggt ggcatcctcc aaagcctccg ggggtacgtc
    15841 gtagtaggtc ggcggcgtca gggtggaggc gttggggtac tggctgccgg aaaacagatc
    15901 aggccggttt cctagcgtgg acatatacag ggaatagaaa cttagcgttt cctcgtccat
    15961 gatatagact ggcacatggg acaggtcgaa gttttccagc gtgacgtagc agatgtaata
    16021 gtcatacggc acttggtagg tgtctgtatg ggtgttgccc tccgcgtccg tccatgtatc
    16081 ggtttcggtg cggtaacggg tttctaccac gacgttttct gtcaggatat attgcttgtc
    16141 aaagagcatg gacaaatcac cctgtacctc cccgatggta aatatcccgt catggagcgc
    16201 cgacagaatg gaaatcagca cataggggtc atggctgatc tcgtcaaggt caaaatggta
    16261 ttcgtcatag tcatgggtgg cctcgtagtt gtccagatag tcttgcagct cggcttccag
    16321 ctccgcgtag gcgtcctcgg cggccaacat atcgctatcc tcggaaaagt aagaggacgc
    16381 cgtgatgccg cttccggcgc tgccgaacat ggcggtgcag gactgtaagc cgccgatgat
    16441 aagcagcatc aaaagcccca acacaaggac ggccagcgcc cctttccagt ggcgggccac
    16501 aaaggaggcc gcccgttcac tttctttggc tgcggccttg gccgctttcg tggaggcccc
    16561 ggctgtcttg gccgcgccct gtgccgccgc gcctgcggtc tggcccgctg tccgggcggc
    16621 cttggcgtac tggcgcttga tctgctgttt ctgccagaac cgggaaatgg ggttgctggc
    16681 cgcctgtgcg atctccgggt tatcccgcaa agatttctgg tagaaatact ccgcgttggc
    16741 agacaatagc ctgcgctcgg ccttttccgc gtcccagtag ggtttcagcc tgtggtgccg
    16801 gatggtgctg cggatggctt ttccggcctg ccgctcggca agttcctccc ccttatggcc
    16861 gccctccaca cccacgtttt catgctcgac ttcatggatt ttcccgtggc cgaatagaaa
    16921 aacctcggaa acaggacggc ctgccggatt gggtttcagg gagggaggcc ccttgtcctg
    16981 tttgtcaaag tgcaggacgg tctttgcttt gccgcttgcc tcgtcaaaga cggtttcctt
    17041 gaccgggacg cgcttcttgg ggatggcggc gcgggcctta tccagcttat cggcccgttt
    17101 gtccgatttt cggatatagg gctgtaaatc cgggtcggcc cgttcttcct ccgacagttg
    17161 gagccgggcg gatggccggt gcagggcagc gtccccctcg gcggccacag ccccggcctg
    17221 cttcgcggct ttcttggcct tatggccgtc atggatggcg tcggcccgtt ccagcagctt
    17281 atcggcggtg ccgcccggcc ccggcgcgga caaatcctgt tcggcctccc ggctggaaat
    17341 gttctccacc tcgccggtgg cctgattttc cagcgtcagc ccgtcgcggg tcatggcctg
    17401 cgtcactttc gccttggctt tcagctcttt catggtggtt cacctccttt gtggcgtcgc
    17461 cgggtcatac tcccgccacc tcgtttaagc gggtcgtcat aatcttgtaa agctgggtgt
    17521 tgtgcgggat ggggttggta aagggcagca ccacgttttc aaagatcaaa aggccctcgc
    17581 cgggttcgga attgtcgatg tacttctgct gttcggtgga caaattcaag cgttccgcaa
    17641 ggatttttct atccccggac gcctgattga gcagcgtaat gaagtcgctg ttttcaagga
    17701 tattttcaat ttccggggag gaaagcaggt ctttgacgtt ctgggtggca cctgttggaa
    17761 tgccgcccca tttcctaaac cgcttccaaa tctccgcaga ataggccgcc gtctgttcct
    17821 ctttcaaaag caaatggaac tcgtcggcaa aataccatgt ggcctttcct tggcttcggt
    17881 tggccgtgac gcgcccccat atctggtctt ggacaatgag catccccagc tttttgagct
    17941 gcttgcccag ctccttaatg tcaaaggaca caagccggtt gccgatgtcc acgttggtac
    18001 ggtggttaaa tacgttcagg gagccggaca catacaggtc aagggcctgc gccacccggt
    18061 cagcctccgg gacatgctga tctaacaacg ctttgtggag gtcggacagg atcggcatat
    18121 tctccgggcg ggggtctgcc agatagggcc ggtagatcac gcgcacagcc cggtctatca
    18181 cggtcttttc aatggcttcc agcccgttct tgccgcccat gacaagctca cagaacgaca
    18241 gcacaaagtc ggatttcagg gccagcgggt tatcgtcctc cgaataattc aggttgatgt
    18301 ccagcgggtt cacaaagtcc ttgctggtag gcgacagccg gattacctgt ccgtggagcc
    18361 gtttgacaag ggggtaatat tcggcctccg ggtctgaaat aaaaatatcg tcaggcgtcg
    18421 ttaagaacac actgacgatc tcggatttac agctcatgga tttgccgctg ccgggggtgc
    18481 cgagcttcaa ggcattgggg caacgggcct gcttcctgtc cagcataatc atgttgcggg
    18541 acttggcgtt gatgccgtaa tacatggccg cgccgccctg aaaaagctcc tgcgtcacaa
    18601 aggggacgaa cacggccacg ctggaagtcg taaggctgcg ctgtatcttg atctgattga
    18661 cgcccagcgg caggctgctt gcaaggccct gttcctgctg gtagtccagc cggacaaggg
    18721 gacagttatg cttttgggcc acgcctgcgg cttggaacac gtcgttattc agcttttgct
    18781 tggtgtcggc cacgttgagg acaaggaacg tcaactggaa cagccgttca ttgcgggtct
    18841 gcaactttgt cagcagcttc ttggcgtcct cgccgtaggt ggcaaggtcg ctgggaagaa
    18901 tgtccatatc gtaaccgctg cggacggcct ttttctgctc cgcaatcttc atagcgtcaa
    18961 ggtcggtaat tttgcgcttg atggtcttga tcgccttggt ctgttcaatg gcctgcacat
    19021 ggagattgac taaaacaccg ctttccgtat tgaggaagtc ggccagcata tcgtccgaca
    19081 gctccgggga caggatttgc aggaaactta ccgcgccgta tttgccgccc atgccgaatg
    19141 tctttgcatt gccgaagcac agggaggacg gggcaataaa atccttggtg gagaggccgg
    19201 acggggccag ccacttccag tcaaaattga atatctcgcc gtccgggtgg tacacgccat
    19261 gcagcaggtt cagccgttcc cagccgtcca tcacatgggc tacggccccc atgctcttga
    19321 aatagcctaa caggtcaaag ccgatgcgct tcaatctggc tcgcgccgct ttcacgcttt
    19381 cggcctcgat ggtgaatgtc aggtatttgg tctttaccat gccgttgttg ccgtttgcaa
    19441 gctgcttttg cagaatgccg gtgtactcgg cccggatgtc gtcgaagtcg tccccctgcg
    19501 gcgcgatctc aaagctcttg gcgtactgca ccgggtcaac tttccgattg aggaaagaaa
    19561 actggatatg aatggaggcg tccacatagt tatacaggtc gcacagtttt tcaaagatag
    19621 ccgtctgcgt gtccggctgg gcaagctgat agctgatgtc cgcaaactca atgcacttgg
    19681 aaaagacgcc gggcgatacc cggcacacgc cgtccgggta catgacctcg taggggatgc
    19741 tctgctgcgc cgtgtggggc ctgccgtcgc ccttatattt acggattacc gcgtcaattt
    19801 cttttcgctg ggcgcgggtc agctttgttt tttcggtttc tcttgggatt tcctttttgg
    19861 acaatggcct ttacctcctg ttccatctgg tattgccgca caagggcggt gtaggtgttg
    19921 tcggtctgat agggacgctc ctttggctgg atgaagcagc actggatgat ctgcataatc
    19981 accacttcaa ggggctggcc gtgacgctcg tacatggcaa gcaaaaagcc cggcagcatg
    20041 gcaaatacca tgagcagggc cgccgcgctg ttggtaagat agtcacgggt gagaaaatat
    20101 aaggggacgc cgatcaccag cgccccggaa aaacagatca gttgccgttt ggtaagccca
    20161 aacacaacct tgcttttcac atgggttaag tccttgggga cggttacata agccatttgg
    20221 cacctccttt cacgtcagga taaggtcaca ttccacctcg ttcccccaca cgtcccagcc
    20281 gggggttttc tgtctggcaa acagctccac gcggggcaaa tcgcccgcca gctctacgat
    20341 tttttcacgg gtcacatccg gctttttgct gtgttgttca atcgggctga taataaactg
    20401 atggacagag gcagaacgac gcttcggctt gccgtgtgtt gccagcaggc agatttccgc
    20461 gtttcccctt gtccagcggc ccagcccgta aaaccatgta aggcttttac ggttctgttt
    20521 cagccataca aaagccacgg tcttgaatga aaagccccac gctttgatta accgcagagc
    20581 ttccggcagc atggggaatg tggcccacaa aaacagcagg cagtctttgg acgccagccg
    20641 ttccaccggc agggcgcaca gctcgtcaat gctcatggtg gaatagtgat tttccgctgc
    20701 gccctgtacg tttttgcagt cataccgcca cggcgggtca gcgtaaatga tgttgtacgt
    20761 tgaaataagc aagttcctcc tgtgtatgct tggattttgg gatcaatgcg ccccgaatac
    20821 ggcctttgat atactgccgg tcttgaacag gcagaagcac agcagcaccg tatagcccat
    20881 acagccccag attgcgccgg atatgtcgga agcggaaccg atattctgta tcagcaccgc
    20941 gtagataccc accacaacca tgattaaaaa ggcttggaag cccagcgcca gcagggattt
    21001 cagataccct tggcccatgc cgcgccattc cgcgttgccc attgtggcaa gggggatagg
    21061 ccccagcgac gtgacaacat agatttccac catgcggcca taggtcacaa ggaaaatgca
    21121 gatggaaagg atattcatgg tgaggcccac aacaagggtt tggaaccaca gccccaaaag
    21181 agcgcccacg ctcatagcct ccaattggct ttcaaggtct ggtatcaggg tgttaaaatc
    21241 aatggatgtc tgcccgataa tcacaccggc gctttgattg acgacgcttt gggtggcgtc
    21301 gaatacgccc atgacgatgt tccatgtgtt cgttacgatc aggattgcaa acgcggattt
    21361 gaatatccag cggaagaaca tggagctgtc aaagtcgtgc atattgttct tttccgttat
    21421 catctggata agctcatagc acatgacaag ggcgagtatg gccccggcta tggggacgat
    21481 cacggtttcc gacaggctgt gcagcatatt gaaaataccg ctgttccatg cctgcggggt
    21541 tcgtcccacg tcggcggcga tttctccgac tttggcattt accgtatcga acagcccgga
    21601 caggttgccc gtgataccgt ccatgaggat gccttttatc cattcttcaa tgatttcact
    21661 aatcacgggt agcacctcct ttcccgcgcc ctcccggtct ggccgggagg acgcggaggc
    21721 gattagttaa gggtttggac agggacaaag gccaggatca gcccagcagc ccggacagca
    21781 ggggaaccag agtgacaccg atcagggcca cgccgccgcc agcgacaagc tgcttgacac
    21841 cctgcgattt tgcccccgga ttgtcctgcc cgtatccctc caacagattg atgccgcccc
    21901 atacgcacag agcgccgccc agtccgatca cgatagtctg caaagtagta actgcggaat
    21961 taaaaaatgc cataaattta cctctttctg ccggtttccg gctcataatg attttttgat
    22021 tttgttgttg gaatgaaaaa agccgctgtt tattcagcgg cggcgtcctc gtccgacagg
    22081 tcgatttcat acaggtcgaa tacttcatcc tgcgttacca cttgctgccg tttccggcgc
    22141 gtgatagtca aaaatctgtc cacgtcaaag gtattcttct tgtcggcgtc ggcaaggtat
    22201 ttgtaccggg gatgcttggt aatatcgaat ttctccgata aaaacgggcg cacaccccgt
    22261 agctgcaaga tacacttgcc gccgtccatc acggcaattt cgtcttggga catcaactcc
    22321 tttcctaatt tttgatagtt caatccgtgg gacgtttggc ttccccggtt ctcgctggtg
    22381 ttgaaactgt caatcgtttc tttccccagc gcatcggaaa tctccttggc atttttgccg
    22441 cgcccactaa ggaaaagcac actatcgcag ttatccgaaa tgatctcggc ggcgtccttg
    22501 taaatcgctt ttagctgcga ctggctctgc aaaataatag aggccgatat ttcacggctt
    22561 cgaatggtgg caatgagttt atcgaaattg ggtatttggc caatgttggc aaattcatcc
    22621 aaaatcaggc gtacatggac aggcagccgc ccgccgtaca catcatcagc ccggtcacaa
    22681 agcaggttga ttagctggct ttggagcata gccagaatga aattaaaggt cgtgtccgta
    22741 tcgctcataa tgagatacag caccgtcttt tcgtccccga tggtgtccag ctccatttcg
    22801 tcgtcctcca tcagctcgcg tacctcccgg atgtcaaagg gcgcaagtct ggcaccgcat
    22861 gaaatcagga tggaagaacg ggtcttgcct gcggacagca ggaatttctt gtactggcgc
    22921 accgcaaaat ggtcggggtc tttctgctcc aaacgctcaa acatgagatc gacggggctt
    22981 tgaaactccg ggtcgtcctc gcgggcttca ctggcgttta tcatttccag cagcgttgag
    23041 aagttcattt cctccgctgg ggcctcgtac cagatatagc cgatcagggc cgaataaaac
    23101 aaccgttccg acttcaccca aaaatcctcc gctgactttt ccccctcgcc cttggtgttg
    23161 gaaatcaggg tatttaccag ctttagcacg tccttttccg aatggatgta gacaaagggg
    23221 ttgtacttca tggacttgga aaagttaatg gtattcagga ttttaatgcg gtagcccgcc
    23281 tgctggaaca tcctgccggt ttccagaacc aaagtgcctt tcggatctgt caccacaaac
    23341 gaagtcggat agtccgtggt cggaaagcat tgcatcaggt tgggtttcac gaaaaatctc
    23401 gttttccctg aaccgctgcc accgatcacc agcacgtttt tattccgcgc tgtcttgggg
    23461 tctttgggcc tgccggtcat ggtaagccgt tccgtttggg tgagcaggat attattttca
    23521 aacttggggt cgatgtaagg cgctatgtct ttggccgtcc cccagcgggc gctgccatac
    23581 tccatgcctt tgcggtattt cttcacgttc ttgctcttgc agtacaccac cagccgcacg
    23641 atcacggcac cggcgatacc gatacacagg tcaaacaggt gcaggcttgg cagcgggttg
    23701 gcaaaagccg ccgcaaaacc atccgcaaaa tgcaggagct tccccgacag gtcagcacca
    23761 gcggccagcc ggtacgcctc cccgcatttc gcaaacaggt acacaaaaat cagatacggg
    23821 aggttcagga tcagcaattt ctttacgtca ggcttcacag ttccagcccc ctttccttga
    23881 ttttctcctt ggcccgctgc ttggtctggg ccgccgcctt ttgcttcaca gcggacaaaa
    23941 ccttgcggat agagggccgc tgctccttgg aaagcgtctt ggcggtaaac tcccgaaacg
    24001 ccagatcaag gttatctgca tccttggcct tgaaaatcac aacgtagtgg ggcggctggg
    24061 tggtcttatc ttttcgtaag gtaaaatcca cgccgtattt cttggcgcat ggcttgaacg
    24121 ctccaatgtt ggcctcggtg atctcaatgt tggagagatc agccccatgc tttttaagct
    24181 gctttaggct ctgctggccg tggtgcagcg tgtttttgcc cttggcccgg tgttgcaggt
    24241 actttttcag cgccgcttgc agcacttgag ccgtgagctt gcccgttttc atggacaggg
    24301 caatggtctt ttgagtaact tcttcctgca atcgcatccc tccttgtcag aaagtcaaaa
    24361 gcggcgtcta aggcggaacc accagacgcc gcaggtagat ataggtcaaa tccgcacccg
    24421 caggccggaa aggtcgtcgg cccggatgcc gacaagatac cagttttcgg ccatttcaat
    24481 gcgggtgggc ctccatttgc cgccgatcat cacgtcgaaa cactccccgc aatgcaggcc
    24541 gccgtaatag tcggccagat caaagcggat gtcgtaacgg tctgttcgct cgtcaaaaat
    24601 caatgcgccc tgcttcatag ggtcgtcctc cttttctcgt tacaggcttt cgccctcgcc
    24661 gcaggaatag tccggcaggc cggatttagg ctttccccaa tcgggctgtg ccatgtcgtg
    24721 cgcgacaagg gccgtgtagt agttggaaat ggtgctgggg gcgttgaaca gcatagcccg
    24781 caggtattgt ttgatattgc ggactttcgt tgtgttctcc cgcagacagt caaggacaaa
    24841 gcggatatgt tcgccggtca gcttcatgta cttggatttc accagctcgg cagggtagtc
    24901 gtccccggcg acacggattg tctttcgggc ggtgcagacg gtttccagca tcaggtctac
    24961 gatttcgtca agctgttcac ggtcaatgct cctgtcctga atgagatagg catactcgat
    25021 gttctccaaa atgatttccc gataaatccg tacagcctca tcctttcctg tccttttccg
    25081 ttccggcggc gtagccgctg cctcgccctc cataggggca ggggtcgggg atgggatagg
    25141 aatggaatgg gtactttgtc catctgtaat tattttttct ttttttgata agtcagttct
    25201 ttgtacttct ttatttaatt gcgttggatt ttccgacgcc ggattatccg atgtcggatt
    25261 ttccaacacc gggttatccg atgttggatt ttccaatacc gggttttcca ataccggctg
    25321 ttcgtagatg gtatagacca tatcggccat tttgcctttt gcgtcacggc cctgctcacg
    25381 ccggatatat ccagcttttt caagctccca taccgctgtc ctgatcgcgt cgatgctttc
    25441 ccggttgata taggacagtc cttttagggt atagtcccaa tcctccggca aggacaacat
    25501 ctgcgacagc aggcccttgg cctttaaggt caggttctta ttccgcaggt ggtgatttga
    25561 catcaccgta tagcctttgt tcttttccac acggaaaact gccatagcgt tgttcgctcc
    25621 tttcactgtg aatttgaccg ctgcatagtc ggtcagcttg cccggctgat agggacactc
    25681 tgcaaactgg cagaattgat atttccaatc cgggcggtaa aatcggcagg tgccgcaatc
    25741 ctccggcgcg tccgccccgc cgccgtcgta gtgatcgaaa ccgggctttt cctgcatcag
    25801 ccgttcaaac gcccggtcag ggccggaagt aaatagcatg gcgtcgcctc ctttctctat
    25861 ttgggcataa aaaagcggcg tcctgttctc ccatgacggg aaagaggaac gccgcgttta
    25921 cggtgtcgta ttcaatttat gatgtgccgt atttggggtg gcgggtatta gcagtatggt
    25981 tcagcatata tgcggctcaa tccgaaagta gtaaattggt agtaaattga gttctcatat
    26041 cctgcgaaat gcccgtattt ccggggcttt cagcgataac ctaaattttt ggaataaaac
    26101 tttcattata ggctactgca acatccatcc aatcagcaat ctctttttgg atctcaggtc
    26161 gtttccagta gccaacgacg attttatttt gtttatttaa tcgagcattg atgaacccat
    26221 attcgcggtc accatgagcg gattgattta aattcatgaa atccatatcg atcgttttcc
    26281 aaggaatgct ttcgttatat tgcgtagcta aatgaagcaa tggtttttgt agaagctttg
    26341 tcccgcggat ccacattttt gctggtgaga aagtatgcat ccaagtgatc acacctgcta
    26401 cttcttctcg ataattgacc tctttcatga tttttgtgat cgtatcagca gtaactgcta
    26461 attcttgaag gcggattgga taaggcaatt ggccattttc attcagttca tcgaccattt
    26521 cttgtgcatg tttctttact tctcgcagtg cttcttcccc atataaatgc tgtgatccta
    26581 caacaaacca aaattctttt tctccaatat tcaacataat tagccactcc ttttatttgt
    26641 tttgtccgta atacgcattt tttccgtgtt ttcgtaaata atgtttatct aaaatccgtt
    26701 gaggcagctc ttctgaaaat gaattgagct gtctggtaaa taaattcatc ttgcatactt
    26761 catctagtac gactgcgttc attaccgcac tttgcgcatc tttcccccaa gtaaatggac
    26821 cgtgtccgtg taaaagtacc cctggaattg ctaagggatc aattttgcgt tctttgaatg
    26881 tttctatgat aacttttcct gtttcatatt cgtacccgct gtcgatttcc tgttgtgtca
    26941 aaaatcgagc acaaggtacc gatccataaa aagtatctgc atgcgtcgtc cccatcgcag
    27001 gaacatccaa tcctgcttgt gcccagatcg tcgcccatgt cgagtgagta tggacgattc
    27061 ctccgatttg aggaaatgaa cgatataaaa cagcatgagt aggcgtatcc gaagagggat
    27121 tgagtttacc ttcaatgata tgattgtcca agtccacaac gaccatgtcg tctgctgtca
    27181 tctcttcata actgactccg ctaggtttga taacgaaata tcgtgtttca ggatcaaaag
    27241 cgctcacatt tccccatgta tatttgacga gtccgtgttt aggcaagtca agatttgctt
    27301 ggtatacttc ttctttcagt tgttccagca ttttctatca ctcctttttc ttgcaattga
    27361 tgaatcgctg ttttttcaat gtcgatcccc tcacggtaac gtctcataaa tatctgatag
    27421 cctgctattt cttctgctga aggtgtgatg gtgattcctt ggtcttgtcc aaacacgtct
    27481 tctgccaaga agttttctaa agacttccca tgtcgatcca tcatataggc tgctaataac
    27541 gcgattcccc acgctccacc ttctccggct gtgtccatca ctgtaactgg tgcctccata
    27601 gcagatgcta gaatccgctg tccaacttct ggtgttttaa aaatcccccc atgccccact
    27661 aaacgatcaa tttggacatt ctcagatttc aatatatcca ttccgattct cattgcacca
    27721 aaagcactgg ctaaatggat ccgcatgaaa ttcgctaaat caaaacggct acctggtgta
    27781 cgtacaaata atggccttcc ttcatttact cctgtaatgt tttcaccgga aaaataacca
    27841 taagaaagta atcccccgca atccgtatcg ccttctagcg ctttgttgaa taataccgtg
    27901 aataatttat ctctgcttat ctccataccc aaagaattgg taaattcttc aaaaatactg
    27961 acccaagcat tgatatccga agagcagtta ttcgtatgaa ccatgcctac tagttctcct
    28021 gaaggtgtag tgaccatgtc gatttccgga tggacatttt ctagttcttt ttctaatacg
    28081 atcatagcga aggcggaagt accagccgaa atgttccctg tccgtttggc tacactgttc
    28141 gtagcgacca taccggttcc tgcatcccct tctggcggac aaaccgggat tcctggtctc
    28201 aaatttcccg tagggtcgat cagataagcc cctgattcgc ttaacttgcc agcttcttct
    28261 cctgctacta gaactttagg caaaatgtga tccaagtcaa tcgctacgtg cgctttttcg
    28321 attaactgac caaaaatatt tttcatttct tgatggtagg ttttcgttga aggatcgata
    28381 ggaaacatgc ctgatgcatc tcctacgcct agtactttct caccagtaag ctgccaatgg
    28441 acataacctg caagcgttgt caaaaaatta atttctttca catgttcttc tttattcaaa
    28501 atagattgat acaaatgagc gatactccat ctctgcggaa tattgtattg aaatttttcc
    28561 gttaatattc gttctgcttc ttcagtgatt gtatttcgcc aagtacgaaa tggtactagt
    28621 aactgttcct tgctatcaaa tgctagataa ccgtgcatca ttgcactgaa cccaatcgac
    28681 ccgattgtcg taagattctc gccatagatt tcgaatactt ctgctgccat ttttcggtaa
    28741 ctgacgcgca gtcctttcca aatatcttct aatgaatagg tccagatacc attttctagt
    28801 ttgttttccc actcataact accagcggca ataggagtaa aagatgaatc aatcaataca
    28861 gctttgatcc tagttgatcc aaactcaatc cctaaagatg tacgaccatc tatgacatct
    28921 aacatacttt gcgcatttac ttccttcata atgatttaac tccctccttc tcgtcaaacc
    28981 tgatcaaacc gtctttttag tagcgcttac aatgattatt gtatactttt gtacgtacat
    29041 gtcaagcggt tatttacaag aatacaataa aaaacacttg ttttgtacgt acataagtta
    29101 taaaatgaaa ttgcttacaa aatctgatca accgccttct cgaaattcta gaaggagaga
    29161 atacttatga aaaaagaaaa aaaagtttcc tcatcgttta tttatttttt tggcgcattt
    29221 ggcggcattc tatttggata tgatattggt gttatgaccg gcgccttacc ttttttacag
    29281 catgattggg gtttggcagg taaagcttct ttgataggat ggatcacgtc ttcggtcatg
    29341 ttaggtgcga tccttggcgg ctctttatct ggtcttcttt ctgataagct tggacgacga
    29401 aaaatgattc ttctttctgc acttattttt atggctggtt ctgtcctttc tgcatctgcc
    29461 cctcacaatg gttcttattt tctgattgca gcaaggattc ttctaggttt agctgttggc
    29521 gctgcatctg ccctagttcc tgcttatatg tctgaaatgg ctcctgctag actaagggga
    29581 agattgtcag ggatcaatca agtgatgatt gcttctggca tgctcctttc ctatgttgca
    29641 gattatttgc taaaagtgtt gcctgaaacg atggcttggc gcgtgatgtt agggctcgct
    29701 gctgtccccg cgctgatttt atttttcggt gttttagctc taccagagtc accgcgtttt
    29761 cttatgcaat ctggccgctt ggaagaggca aaaagagtat tgaactatat tcggacacca
    29821 aaagaagctg aacaggaatt cgaacaaatc cagctgaatg tcaaacaaga aaagacaacc
    29881 ggaacttctt ggcatacttt gtttttagaa aaatatcgtt ccttagtcat tgccggtatt
    29941 ggtgtagcag tattccagca atttcaagga gctaatgcta ttttttacta tattccgctg
    30001 atcgtagaaa aagcgactgg gcatgcagcg agcgatgcat tgatgtggcc gatcatccaa
    30061 ggaatcattt tagttgctgg ttctttgctc tttttggtta ttgcagacaa gttcaatcgg
    30121 cgaactttat tgaaaatagg cggtagcgtg atgggacttt cattcatcct accagctgtt
    30181 ttaggaactg tactggatgc tcatacaaat tcgttgttga ttctcttgtt tttatgtatt
    30241 tatgtcgcat tttattcttg cacatgggct ccactgacat gggtaatcat aggcgaaata
    30301 ttcccactag ctgtccgcgg gcgagcatct ggcctagcct cttcttttaa ttggattggt
    30361 tctttcctag ttggcttgct ttttcctgtg atgactgctt ctatgtctca agaaatcgtt
    30421 ttcggcattt ttgggatcat ctgcttttta ggggttttat ttattcaaga gatcgtacca
    30481 gaaactcgtg ggaaatcttt agaggaaatc gaacaaagtg catctaaaaa aacttatcct
    30541 aaacgtattt ctatccatca ttcttaaaga ggttgtgaca gaagtggtca gcttcaagaa
    30601 ataagaagga accgcttagt ttccagtcac aaggaacaat ttcaaaaaac agcttctcat
    30661 gtttgatgaa tattgtgact tgtgaccagt tggtaggaga acaccgttta gtggagaggt
    30721 ggtgaaagaa acgttcagcc ttgagcgatg acaaaagctc tcacaaacat tgcgacgagt
    30781 aaccgtagga gcaataagag gcggtaaaaa cccgtctctt atttttcgtt ttctttcact
    30841 gtttcccgtt caactagtac aggttcatag agaatatttg gctgtgcctg tcctttttca
    30901 atcgttgtga cgatccaccg tgcggcatct tgtcccaact tttcttttgg atgcgtcaat
    30961 gttgtcaatt ttttattccc taaatggctt aaagaagaat cgtctgttcc tacgatcgat
    31021 aggtcatctg gaatatgata gccattttct gtcaacttat ctagcattaa actagctatt
    31081 tgatcgttat agcaaatgat gccatctaaa gcttgttctt ctttcaaccg ttgtactgtt
    31141 ttttcagcga ttgtttctcg tgtttccgtg gtgaaagtaa tgatatcttc cgtcaaaaaa
    31201 cgcacattat actgttcaca cgcgctgata aaacctttca tcctgtattt tccttgaaga
    31261 tcgtcgattt ttgtgatgaa caacagacgc tgatgtcctt tttttatcaa atattctgct
    31321 gccataaaac cgactttcac atcatctaaa caaatataag aggcatttaa ctcttcataa
    31381 gcagcattga tcatcaccat cggaatgcct tgttctctca aagcaacata aagtgctaag
    31441 tttgggttat actgattact tttcgtaggc tcaacgatca aaccatctac cccataagca
    31501 atcattttct tcaaacactc tttctccaat tcgtgatcgt tattcgtact ggctaaaagc
    31561 aatgaatacc cagattctcg taattcattt tcgattcctc ggataatcga cggaaaaata
    31621 taatcagaga gatatgtggt gatgacaccg atcgtttttg ttctgttcaa tggtgttttt
    31681 tctttcttat agctgtcatc tacatatgtg cccgaccctt tttctttacg cagatagccc
    31741 tcatttacca acacagcgat tgcttgccga atcgtatgtc tgctgacgtc atatatttct
    31801 tgcagcttga attctgaggg aatggttgta tttacttcgt attcctcacg aaggatcttt
    31861 tgttttatct cttctgcaat atcttgatat tttgccattt gccttgcccc tttttatttg
    31921 tacgtacata tatcataacg agtctgcaag gtttattcaa gcaaaaatca aggtttcttg
    31981 tgctcataag gcatacggaa caggttcacc aaattctgga aatccttgct cattccacgt
    32041 aaagcattgc gcgttcgcgt gccgattagg attgtctaac ggatcccctt tttggttctt
    32101 ctctggtcga gcatgataga tcaaaatatc aaagcacccg tcttctgaaa ccgtaaacga
    32161 gttgtgacca ggaccaaatt gcttattttt ttcagaagaa acgaatactg gctccgataa
    32221 tttatgccat gattctttta ataaaagatt cttgtgctca tcagcccaca gcaggcccat
    32281 ggcatagttt tcatctgttg cactaccaga atacgtaatg aatattttcc cattgcgagt
    32341 aaggactgct ggaccttcat ttactgaaaa accccgtttt tcccattcat actcaggtat
    32401 agaaaggagg atctgcttcc cctttaacgt ccaaggatta tccatttcgg atagataaag
    32461 attagaattc ccagtaattt caggatcttg ttgggcccac acataatata gctttccttg
    32521 agaagagaaa gttgttccgt ctaaactgaa agtttccctt ttcgttttta tttgtccctt
    32581 ttctatccaa tctgtattca ttggatctat atgctgattt tcaagtacga acatgcggtg
    32641 atgatgagat tcatcacgta tagttttatg attgcttgca gcaaagtaaa tataccattt
    32701 tccattgata taatggactt caggtgccca gatcaattca ctcatcggtc cttcttcatg
    32761 agcctgccat acaatcaggc ttgcagcatg ttctaattca ttcagtgact ttgcccttct
    32821 taattcaatc acttggtagc ctggaaccga tcctgtaaaa taataataac catctgtatg
    32881 tttatatacc caaggatctg cccgttgccg aacgatagga ttattataaa gtgtcttcat
    32941 cataacaaat ttcctcacat tttctttatt ctaattacat tccaagagta tttttctatc
    33001 cctacattta attcgtcatg tttttctatt gaaaaatagt ttatttcagg ttttattttt
    33061 tctggttctt cacgtgtatt tttgtccaac agatcgctac tggttaatgt gtagtgctct
    33121 ccttgatcta gcaaattgaa atcatgttca atcgttatct tttgttgttc atttgtgcga
    33181 ttgatcaaga aaatagtcag ctgattgccg ttatctacga tcacactgtc cacataagga
    33241 acatttttta tcttttcaca atcataaaca gggcaaatga tttgttgttt caatacttga
    33301 cctttagcat atttcgataa gtgttgcatc acataataag ttggattcct ccatgcttgt
    33361 cctttagcat ctgtcagtat taaaggtatt gtgtttacta acaatgattg acaactaatc
    33421 tttacgcgat ctgcgtgtcg taaaatagcc agccctaatg aaccaaataa taatgtatct
    33481 tccatagtaa agtaacacca atcgatggga ctaccgactt caaaatccct atgtcttttt
    33541 tccggttggg catgtacatt ccattcatca aacgctagat acattgtttt ctcacttctc
    33601 aaatatcctt ttacataatc acaagtagca acgatttctt caatttgacg atcgaatcga
    33661 taagcttttg caaggtatgt cgctgtatca tcacgctcat ttttaggagg tttagtcaag
    33721 tcttcttcat catacttatc aatatagtta tgcaaagcta aataatctac attctcataa
    33781 gcttcttcta atgcgatacg atcccattca gggtacgatg gtaaacgtgg cgtagagctt
    33841 ccaactaaga ttgtttcaat tgaatcatcc actaacttca tgacttttga ggcttcattt
    33901 gctaacctac catattcata agcactctta gcccccactt gccatggacc gtctagctca
    33961 ttccctaaac accataattt aacgccaaaa ggcttttttt gcccattttt tattcttaaa
    34021 tcactccaga aggttccttt tggaaaatta caatattcta ctaaattttt tgcttcatca
    34081 attccttttg ttcctaaatt caccgtgaat atcggtttcg cttgtacatg actgatccat
    34141 ttaaaaaatt cgtggagtcc aaaagaattt ggttctatac ctcgccatgc taaatcaatt
    34201 tttttggtcg ttgttctttc ctacctacag tatccaccca atcataacca gatgtaaagt
    34261 ttcctccagg atagcgaatg acacctaatt ctaattcctt tacataagag aggacatctt
    34321 gtctaaaccc gtcaccatca gctgtttcat ggcccggttc ataaatccct gtatagacga
    34381 cacttcccat atgctcaaca aatgagccaa acagccgaga actgatctct cctaccgtaa
    34441 aatcctctct gatttttact ttcacttctt cgtccaacag ctttccctac ctttcatttc
    34501 ctatagtcaa gataatagat acaagtttcc atacgccacc agcaaagata aaaataaaag
    34561 gagggaaaag aaatatgagc agtacaaatc ctaataacaa tacgcaacaa agaatatttc
    34621 tcaaaaaatc aaaaaatact ttccatgcac tttgttcaaa aatttgtaaa aatgtgatat
    34681 ctttgttttc agaaatcaca tatatccagg ataaaagaaa catggaataa ataagtaaaa
    34741 ctacatatcc actaattgaa agtacgattg tctgttcttc taataattga ttaacaagaa
    34801 aataaataat gatcgttaac agactaagga acaagttctt accaaaatgt tgctttattc
    34861 cttgaaagaa aaaataaatg atatttcctg atccctcacc tttccattgc gccattacat
    34921 aaaaaacagc acatgtagca ggcacgatag taataacagg caaacacacg attacccaga
    34981 gaatacctaa taagatgtaa tcagaaacca caatcaactg tccataaaat ttagtctcaa
    35041 ctattttcat cttcctcact ctttcattcc agacatagct gttccttgaa caaaatattt
    35101 ctgtgcaaaa atataaacca ctagtaatgg cagcattgaa ataaccgttc cagccattac
    35161 aggtccataa aaagaaatgt tctgccctgt aaataaagct aaccctgctg gtaaagttct
    35221 catttttgaa ctacttgtca atatcaatgg ataaagcaag tcattccaac tattcatcag
    35281 cgtgaaaatc cctaatgata aaagagtagg tttgctcaat ggcaacatga ttttcaaaaa
    35341 aatattaaac tcacttaatc catcaatgcg tgctgcctct tccaaagaat ctggtaaagt
    35401 aataaaaaag gaacgcatca tgaagatacc aaatgcagtt gtcatacgag gaatgatcaa
    35461 acctgcataa gtatcaagca tgccaagcaa attgacttca ataaatagag gaatcatgaa
    35521 gacttggaat gggatcatca ttgtcagcaa aacgaaatag aacaaaactg attttccttt
    35581 gaaacgcata cgagcaaatg cataccccgc aagagaatca aagaatacag aagtgatcac
    35641 tgtccctcca gcaaaaatca ctgtattttt gatgtaatct aataaaggga tcgttgtcca
    35701 aaccttaata tagttatcta gggtatagct atctgcaaat attctaggcg gaaatgagat
    35761 aatgtctttt tcgtgtttaa aagaagaaat aatcagccac aaaaaaggaa acgcaataac
    35821 caacaatata actagcatac taatcgttcg aatgattttt ttaccactaa ctgcttttcg
    35881 actattcaca gtaactgtaa tcgagctttc tggtgccata caggtttccc tcctatttca
    35941 tttgtttttc tttccgtgac atgtacacat tagtggagat agctatagtt gcaacaatga
    36001 taaacaaaac cgaagacagt gctgatgcat agcccaattc ataaggtgct gtaaatcctc
    36061 gactgtaaat atattgaaca gctgtttctg tcttaaattg tgggccacca gcggttgcaa
    36121 catatacttg gtcaaacact tgcatcgaac caatcagatt cgttaaaata caaaaaccta
    36181 aggagggaac gatctgaggt agcgtaatgt taaaaaactg ctgtcgattt gttgcaccat
    36241 ccatttgagc agattcatac aaagagggag agattccctg aatagcagtc aagagaatcg
    36301 tcatagtaac accaaaattc ttccaaacag tcatgatggc taccgtcggc atagcaaggg
    36361 ttggatcgcg aaaaaattga gggatcggca agccgacttg tgaaaacaag taaggaatcg
    36421 cccctacatt cggatcaagc aacatagaaa aaataatcgc aattgacgtc aatgaacaaa
    36481 taactggaat gtaaaatgtc gaacgacaaa aacgattgaa tctggtattt ttagataatg
    36541 ctactgctgc taataaacca acgataattt gtgttggcgt ttcgagtacg gtgaaatata
    36601 aagaatgaat caacgaatta actgctcgtt catcactaaa tatacgtgtg aaattttcaa
    36661 aacttacaaa atttcttgat gtaaagaaaa tattcaaatc tgtaaaacta atagcaaatg
    36721 ttcctaaaag cggtatgaca gtaaataata ataaaactaa aaaagatgga gttaaaaaca
    36781 aatacgcagc acgatcagga cgattccaat atttggtgaa tccgttcata tagtccacct
    36841 catctttcat tttgataaaa tatacaatct tggtttaaac gaatctgaat aagatatccg
    36901 aacaatcgct gtgatttttg caataacacc tatctgcaaa tactaggtcg atcattcaga
    36961 tatctgtatc ttgccaacag tctatcctgt ataaagttct gtactatttt tgcagtaatt
    37021 gattgatggc atcatctgca tcgttcatga gtgtctcagg atcttctcct gctaataatt
    37081 tttcaatcag tggattgatg atatcgttat tgatcgcaga gatttgggta aaacctggta
    37141 aatatggctc tgcatagtcc atttgtttcg ataattcaga tacaatagga tcatttttta
    37201 cttcttcatc ttttgctact gaatccaagt aggcaggaaa accattttcg atactccatt
    37261 ttttaccaat ttcagttgta ttccaatatt tcaaaaactc atagacagct tcttttttat
    37321 tattatctgt acttgccgga atggcatatc ctacgccatc taaaatagct gtttttttgt
    37381 ctgaatcact cccttgtggt aaggtagtca cattataatc aatctcgttt gctttcaatc
    37441 cgttatttaa ccatggccca ttgatttcaa tggctagttg accagcattc attaaattgt
    37501 ccatttcggc gccagaaatc gattctggac cagtcttgtc tacatggatc attttttgga
    37561 tcgcttttaa cgttttaagg ttctcaggag acgcaaattc agacttagta taatcatcgt
    37621 tcactaattt accgccattt gctaacatcc agttatataa cggtgcagtt ccatccttat
    37681 tgaagacaaa acctgataca tttttactac tatcagttaa ttttggtgcc atttctgtca
    37741 attcttccca agtagtaggt ggttgttcag tatctaatcc agcttgttta aacaaatcat
    37801 tattccaata catatacatg ccttgtacct gcatggggac aaaatactgt ttaccttcta
    37861 cttcacctaa ttcaatagcc gtttctttaa aatcagattt atctactcca tcatattccc
    37921 agaaatcgtc taatggttgt accgctccgt tttctacata ctgtgcaaaa tctggataat
    37981 ttaatgcaat aaagtcaggt gcttttttag aagaaatcgc tgtaggaagt ttttcattca
    38041 aattggccca agtcatgata tccatttcaa ttttgatgtt tttatcattt gttttattaa
    38101 attcattaac gatttcttgc aatatttcac catcagatgc agtaaaccca ttccaaaaag
    38161 tcaaagtcac ttctttatca gaatcagatt ctgctgaact tccgccaccg caagctccta
    38221 aaatacctgt tgcagctacc aacaaagagc caattaacca ttttttacct ttcatttttt
    38281 gttcctcctt catctgataa acgacatctg accacattcc aagatagcgg tttcaataaa
    38341 caattgattt tcccatcttc agcttttaca tttgttgaat gacttggttt tacttgttca
    38401 cttttaggaa gattagttgc ttttgtatca aatccactca tttcagaaaa atcaatcact
    38461 ccctctaatg ataattcaga caagtgaaca gttagattca tttcttcttc tccacggtta
    38521 actgcaaata tgacaagttc tttgtcattt attacggcta tactttctaa atacggcact
    38581 tcttcaaaat cttccgtcgc atagtttgct gaacgaattt gtgggcttaa cacctctcct
    38641 tgtccataca cagcagcttg cataaatgga taatagatcg tctgtctcca agcttctccg
    38701 tttgtttctg tcctgattgg tgcaataacg tttaccaatt gagcaagaca agcaatcttt
    38761 actctatctg catgtttcaa taaagtgatt aatagacagc ctaatagtaa tgcatcttca
    38821 aaattatagt tatcttctag taaaggagga gcaatctgcc aaggcgctgc ttgctcatct
    38881 tgttccgctg aatgatacca aatattccat tcatcaaagg acaggttgat ctgcttctta
    38941 ctatgtttct tcgccttgac tgtatcgcac atcgctgtca cttcagaaat gaaccgatcc
    39001 atgtctaagg aacgtgcaag ataatgagaa agatcatttt tttggttgcc ataatattga
    39061 tgcagagaca aataatctat ttgatcgtac gcttgatcaa gaactgttaa ctcccaatca
    39121 ccaaatgtag gcatttgccg attcgaactt ccgcataaaa ccacctcaat tgaatcatct
    39181 acgagtttca tcgccttagc cgtttcctct gctaaccgtc catattcttc cgctgtttta
    39241 tgtccaatct gccaaggacc gtccatttca ttccctaaac accatgtctt aattccaaaa
    39301 gggctctctt gaccattcga acgccttaaa tcactccaat aagttccttt aggaaaatta
    39361 caatattcga ctaaattacg agctgcatct actccacgag tacccagatt gacagccata
    39421 ttgatttcgg cccccacatg ctgacaccag ttataaaatt catgaatccc aacttcattc
    39481 gtttcaattg tccgccaagc taaatccaac cttctaggtc tatttgctat gggcccaata
    39541 ctgtcttccc aacgaaatcc tgacacaaaa tttccaccag gatatctaat catgggaatg
    39601 ttcaattctt ttaccaagtg aatgacgtct tggcgaaatc cacttttatt agctgatgga
    39661 tgatctggct gataaatccc ttcatatact gctcgtccca tatgttcaat aaatgaactg
    39721 tacaaccgcg gatcaacttt gcctacacgc ttgacactac taatcaacat tgtggcttcc
    39781 ataactgacc tcctttaatt tatacatgaa taatacacct cgttgaaagc gttgtcaata
    39841 atataaatgt taaacttact tattttttat cgattttaat taaccaaaat attaataatg
    39901 attaaaacaa ataatttaat ataactttta ttaacaaata tgttaatata taagaaaaac
    39961 cttttaagag gtgatatata tgcaactaca aataaacgaa gaatccttac cggtatatga
    40021 agcattagct agtaaaacaa ggatcaagat catccagcta ctttccaaaa aaaagatgaa
    40081 tgtcaaagat ttggcaaaag aacttggagt gagcagtgct atcacgacga tgcacgtgaa
    40141 aaagctagag gaagcaaaca tcatcaaaac agaaaaagta ggacaacaaa aaatttcgag
    40201 ccttcgtgtc gataaaatcg atattagttt tccagaaaaa atattcaatg cttttgatac
    40261 gaaagaaaca tcgataccta ttggtcacta tacaaattat gcaattgaac caacatgcgg
    40321 tttagctacg atccatgatt ttatcgggaa agtggatgaa ccacgctatt ttatggatcc
    40381 tcgaaggatg gatgcccgca ttctctggtt taccagcgga tttgtcgagt atcaggcacc
    40441 taatttttta aatacagagg atacattgga gatgttggaa gtttctgtgg aaatttcttc
    40501 tgaatttcct ttttcaaatg acaattggcc ttcagatatc actttcagcc taaatggtgt
    40561 ggagctagga acatggacga gccctggaga ttttgctgat atccgcggta aatatacgcc
    40621 tgattggtat ccagataatc ttaatcaata cggcttgctg aagacgatcc gaattaccaa
    40681 acacttgacg aatatgaatg gagaaccctt gtcaaacatc acgatcaacg acatccctaa
    40741 agagcaagac acttggcatt tgcgaatcga agtgaaagac gatgccaaac atgtgggggg
    40801 ctgtacttta tttggtaaag gattcggtaa ttacgatcag gatatcaaat taaaagttta
    40861 ctacagctga tatttttctt ttctatttta taaaacaaaa acagccaatc cctatgaagg
    40921 gacggctgtt tttgctttat tgttatttcc agaaatcatc caaaacggaa attggcaaat
    40981 gtcgtttatg ttgtgtcttg ttccaccatg cttcgatttt ttcttgtgct tgagcgggaa
    41041 cttcttttcc ttctagataa tcatcaattt cattatatgt gacacctagt gcgacttcat
    41101 ctgcaatcat tggtttccca tcttcaagat ctgcagtcgg aatttttgtg tataattttt
    41161 ccggtgcatt caatgcttga agcaattgtt tcccttgtcg tttgtccaaa cggaataatg
    41221 gcaaaatgtc ggctccacca tcaccaaatt tcgtgaagaa tccagtaatg ttttctgcag
    41281 catgatctgt ccctaatacg gctcctgctc tttctccagc tacggcatat tgcgtaatca
    41341 tacgttgacg tgctttgata tttcctttgt taaaatcgct gattcccaca cctgcttcgc
    41401 ttaatacttg tacttgtgca tcaacagctg gtttgatatt tactcgcaga ctaacatcgg
    41461 gctggataaa gtcaagagca gcttttgcat cttcttcatc tgcttgttca ccataaggaa
    41521 gacgaacagc gataaattga tagttttcat cttttgtttc ttcacgcatt tcttccatcg
    41581 ttagttgcgc caaacggcct gctaaagtag aatcttggcc gccgctgata cctagtacaa
    41641 aagttttaag aaacggatat tttttcaaat atgctttcat aaagtcaata cttttacgta
    41701 tttcttcttt tggatcaatt gttggtttga cacctaattc attgataatt tctgtctgca
    41761 ggctcattta ttctcctcct atgcttctgt atgaagttct gctacgcttt ttttcattcg
    41821 ttccatgata gccattttat ggttccagca ttcagtagac agatcgactg ggtatttttg
    41881 cggattcaag tctcgtttat actcttccca tagtgaatct agattttctt ttgtatattc
    41941 tttgatttcg tttagtgcag gtaattcgta aactcttttt ccttcgataa agatatcttg
    42001 taaaactggg cgagctgtaa agtctcgaac agttttattg ataaacgtat gcactggatg
    42061 gaacatgaag atagcttctt cttctcgagg gtcttcatcc cataatgtca cgtagtctcc
    42121 ttcagatttc ccatcaaaat ttcgagtgat gcgccacact tgttttttcc ctggagtagt
    42181 tactttttct gcattgcttg ataacttgat cgtatccatc atttttcctt catcatcttc
    42241 gatcgatact agcttgaata ctgcaccaag ggctggctga tcataggctg tgatcaattt
    42301 tgtcccaaca ccccatacat caattttagc tttttgcatc tttaaattca aaatcgttgc
    42361 ttcatccaag tcattcgaag catagatttt tgcttccgta aatccggctg catctaattg
    42421 ttcccgaaca cgcttagata tataggccat atctccactg tcgatgcgta cgccttggaa
    42481 gttgattttg tcacctaatt ctttcgccac gcgaatcgca cttggcacac ctgatttcaa
    42541 cgtatcataa gtgtcgacta agaacacgca gtctttatgg gttttagcgt aggccataaa
    42601 tgcttcataa tcatttccat aagattggac taacgaatga gcatgggtcc cgctagctgg
    42661 tatcccaaat atcttcccag cacgtacatt gcttgttgca tctgctccgc cgatatatgc
    42721 cgctctagtt ccccagactg ctgcatccag ttcttgtgcc cgtctagttc caaattccaa
    42781 tagtggatct tctccgatga cagatttgat acgagctgct tttgtcgcga tcaacgtttg
    42841 gaaattgacc atattcaaca gtgctgtttc tactaattgg cagtgcgcta aaggcccttc
    42901 cacttggatc aatggttcat ttgcaaaaac tagttctcct tcacgagcag aacgaactgt
    42961 tgctttaaat tcaaaatttt gtaaatactc caaaaaacct tcaggataga cttctaatcc
    43021 acgcaagtaa gcaatatcgg aatcattgaa cgtcagattc tctaaataat tgactaaccg
    43081 ttccaatcct gcaaaaaccg cgtatccgtg gttaaaaggc atttctcgaa agtaacattc
    43141 aaaaacagca tgtaaatcag ctcgacctaa ttcccagtat gtctgcatca tattgatttg
    43201 atatagatcc gtatgcagcg tcaaactgtc gtctgggtaa gtattattca tcttgtatta
    43261 ctcctcttgg caagttttca tttcctaccc attataacaa aaaaaattaa taggaaaaga
    43321 aatcttccat tttttctgaa aaagcacatg ttttacggat atttcttgct aaaaatgaac
    43381 tccatctgct aaaactatcc tttcttattg gtatttaacc taaacgagaa agaatactta
    43441 ttttattcaa tgtatccgag acacgaagaa attagcgttt tctatttttc ttacttgata
    43501 aaataagtag attttcctac tacaatcgta gccgttaaga taccgatgat tgaacaaata
    43561 taaccaaatg tctctacaac ataatcaatg gcaaaagttt ttgaagcaat aatacgtctt
    43621 tccttttttg cttcttatcc ccaaagaaac ggatataact tattatgtat tgaatttttt
    43681 tggaaaggcg aattatgaca agatatacct tgcgttgaaa aaactcgcgg aaaaaatatc
    43741 acacgttttt aaaaagatac aaagtaagaa agcagctgtc aatagaatgg aaacaaaaat
    43801 ggcgagacat caatcagtct cgccttgttt tttattgtat acattagata tggagcaggt
    43861 taccataaag atgattatta gtcgttatta aatagaatcc ttcgtatttt tttgttctat
    43921 cactacaata tctttatttg gacgtttgaa ttgtattccg gcacgttcta gctcctgttt
    43981 cactcctaca tggactttga catcttctcg tgtcattttt aaaacgtgat gaatcgcata
    44041 gtcgatttct tgccttgtga tttttttctt cgtattgatc atcacgactt gctttttatc
    44101 atatgtgtct accaatagca gttgtgttcg atctaacgaa aataatttgt aataattaat
    44161 agccgtattc ccaaaaaaga attccactac tttaggataa aatgtcttaa tatttaaatt
    44221 actattcaca ggtgtttcga ttagcttcat ctcattcctc ttttctatat agtcgattta
    44281 gatccaatct taagttatgt taccatcttt cctagcatta aggaatcggt tacaattgaa
    44341 cctttaaaga caaaaggatt taccttttat cacttaatag tataacataa tttcatgaga
    44401 aaaaaataca attttttctt gaccatctcg ttacgtaaag gattatgctt acatttgtca
    44461 ggaggaaaaa taatggagta cacaataaag aaaatgtcag agatatcagg agtcagtccg
    44521 agaaccttgc gcttttatga tgagattgga ctgctaaaac cagctaggat caattcttca
    44581 ggttatcgga tttatggcaa aaaagaagtc gatcgtctgc aacacatctt attttatcga
    44641 acaatggcat tcaagttgga tgatatccaa gaggtcttag acaatccatc ttttgaccac
    44701 cagaaagctt taatcaagca tcagcaaatg ttgctggaaa aacgggcaca aatcgatacc
    44761 ctcttgacaa ctgtccaaca gacacttgat atgtacgaag gaggaagaaa aatgagtgac
    44821 aaagaaaaat ttgaagggtt taaacaacaa aagttgaaag aaaatgaaga atcctatgga
    44881 caagagattc gacaaaaata cggaaaaaaa aaggttacag catccaatga aaaatggatg
    44941 aatatggata aagaaacgta tgaagaaatg caaactgttg aaaagcagat gttatttgat
    45001 ctcactcttt acttaaaaga accagaagat gaaagcttag cagaccgtat cttccaagct
    45061 cataagaagt ggttatctta cagctggcct gaatatcagc caaaagcgca taaaggacta
    45121 ggaatgatgt acgaagccga tgaacggttc actgcatatt atgacgagcg aagtggtcat
    45181 ggtgcagcaa aagctttaaa tgaaattatc caaaaaaagg cgtaatcttt tacatgatcc
    45241 aacaaaaaag tacacgtaaa atgacctaat aacaaaacag cagacaccca agttagattt
    45301 ttatgctaac ttttggtgtc tgctccattc tttcacaagt tttttcatcc tactttaaat
    45361 atattcatcg ttgaataaac gtataaggta ttttcacttt atcctttttt tctgtaagaa
    45421 acaattgaaa tgccatttct ccgcaagctt ccagatggtg gtcgatggtt gggaaaccaa
    45481 gaagctcgct gatcagcaaa ttatcgcgtc caatcaccac tggtgtctta tcttgcagat
    45541 agctttgcaa gatgcctgct gcaaccatat ccgaatttgt aaagacacca tcaactccaa
    45601 gctctttaaa aaagaagcct gcttgttttc ctttctctgc atctatacaa tcccaaaaaa
    45661 caagtgattc atcaaaagat ggaaaaagtt gatgacatag ctgcaaagtg atttttgagt
    45721 tataacttag cctgccactt cgccccaacg tgatgcccaa ttgctttata ccttgctgct
    45781 tcaaataagt aagaccttct gtaattgatt gttctcgatc aataaagaca cagcttgcct
    45841 gttttccctt gatttcttca caaaaaacta gaggtccata tttttgatat gccaataaat
    45901 catctagtgt attggcacga gacgtaatga tcaatccatc gaaagcttta gctgcaaatt
    45961 cttcaagata ccttcgctct ttttctttct gatagcccgt cggtaaaagt gtcactttgt
    46021 aatcataatc aaacgctgct tcaatgatcc cactgatcaa ctgatcaaaa tacggatgat
    46081 tggtataagg cagaatcact ccaatgcttt tcgtttttcc ataacttaac tgtctggcat
    46141 ttgcattagg gatataatcg acttctttca tgaccgcaag tatttctttc cttttttcct
    46201 catctacata tggatgtcca ttgattacac gtgaaatagt agaaactgaa taacctgtga
    46261 gctttgcgat atctcgaatg tttgccactg ctgcttcgcc acctatacaa aaagattttc
    46321 ttgtaaatag tctaccacag ctggaccgca ttcaaaaaac tgatacattt ttccttcatg
    46381 cgaaaaactg atccgctgcc cgccccaata tatatctttt gtcaaatttt cgatttcatt
    46441 cattggtatt tcttttacta tattcctatt caacccttga aaactgtaca acgttaatac
    46501 ggatcccttg aactcgacaa acgcataaaa ataattgttc gttgtgccat ctgttatctc
    46561 tacataagta ttcattgcaa gccctccttt tgatactttg agtatagtgt atgaaacgcg
    46621 tctcatagca aggagtttgt tttgccaaag aaaagtttta ttcctctttc attattacca
    46681 aagtctctta ttttaaattg aatacattat aatgatactg taaatatatc tttattatta
    46741 gtgaatggat atttactttt aatagataaa atattataac tattaaaaat aactattttc
    46801 attataatta cacacaaaaa agagcgtgag acaaaagtaa agaacacttt tgtctcacgc
    46861 tctaaacacg tataaacagc ggaagcagaa gcaactcctt cggaaataag ctgaaattca
    46921 caaaaatttg aaaagcaatt tccgtgaatt tcttcttatt tcttggagtt aaacgcttct
    46981 gttccagcct ctttttatct gtctttcact aatgatcagt tgtagataag caagttgctt
    47041 tttcttacat cataccgccc atcattgatg gatccattgc aggagctgct ggcgctgctg
    47101 gttctggttt atctgcaacg actgcttctg tcgttaataa caaggcagaa acggaagcgg
    47161 cattttgcaa ggcagaacgt gttactttag ttgggtctac gatacctgct tcaaccatgt
    47221 ttacccattc tccagtagca gcattgaaac cagtgcctag ttccacgttc ttcaatttat
    47281 caacaatcac tgatccttca taaccagcgt tttcagcgat ttgacgaatt ggttcttcta
    47341 aagcacgaac aacgatcttg atacctgttg ccacgtctcc ttctgcttct acagcagaaa
    47401 ctttgctgat aacgttcact agagctgtac caccacctga gaccattcct tcttctactg
    47461 cggcacgtgt agcattcaat gcatcttcaa tgcgtaattt taattctttc aattctgttt
    47521 cagtagctgc accaacttta acaacagcta caccacctgc taatttagct aagcgttctt
    47581 gtaatttttc gcggtcaaaa tcagaagttg tttcagcaat ttggtttttg atcaattgca
    47641 cacgagcttc gattgcttct ttttctccag aaccttctac gatcgttgta ttgtctttat
    47701 ctacaacaac tttagaagca tttcctaagt tttcgattgt tgcatctttc aattctaaac
    47761 ctagatcgtc agtaattact gtaccacctg tcaaaatagc gatatcttca agcattgctt
    47821 tacgacgatc gccgaaacca ggagctttta cagctactac gttgaatgtt ccacggattt
    47881 tgttcaatac aagagttggc aatgcttcac catctacatc gtcagcaata atcaacaatg
    47941 gacgtgattg ttgcaagatt tgttctaaca atggcagaat atcttggatg ttagagattt
    48001 ttttgtctgt gatcaagata tatgggtttt ctagaacagc ttccattttg tcgttatctg
    48061 ttaccatata ttgtgataag taaccacgat caaactgcat accttctaca acatctagtt
    48121 ctgtttcgat cccttttgat tcttcgattg tgatgacacc gtcgtttcca actttttcca
    48181 ttgcatcagc aatcaaatgt ccaactttat cagaacccga agaaacagct gctacttgtg
    48241 caatggcttc ttttgaatca acaacagttg agatattatg caattcttcg actgctgctt
    48301 ttgttgccaa ttcgatcccg cgacgaatgc ctagaggatt agcacctgca gttacgtttt
    48361 ttaaaccttc gcgaacgatt gcttgtgtca gaacagttgc tgtcgttgta ccgtctcctg
    48421 caatatcatt tgtttttgat gctacttctg atacaagttt tgcacccatg ttttcaaaat
    48481 gatcttctaa ttcgatttct tttgcgatcg tcacaccatc atttgtgatc aatggagagc
    48541 cgtaagattt ttctagtacg acatttcggc ctttaggtcc taatgttact ttcactgtat
    48601 ctgctaattt atctaccccg cgtaacatag ctgcgcgtgc gtcttctgca aatttcaatt
    48661 cttttgccat gattgattca cctcattgat tatttttgat tattttttta tcttccaaat
    48721 ttactcaaca atcgccatga tatcttttcc tgcgacgatc agatattctt ttccttcgta
    48781 ttttacttct gtaccggcgt atttttcgaa cataacttgg tcgcctgctt ttacagcggc
    48841 aggaactttt tcaccgtttt ctaacaaacg gccttcaccg actgcaacaa ctgtcccagt
    48901 ttggggtttc tctttagcag cagaagctaa aacgattcct ccgacagttt tttcttcttc
    48961 ttttgcgact tcgataatga cgcgatcacc taatggtttt aacacgataa atccctccga
    49021 taactctttt tttaatctgt tagcactctt aaccttcgag tgctaaccta catttttaat
    49081 aatactcatt ctccctcttt tttgcaagct tttaaatcaa agaaaagaaa ttttattctg
    49141 acagctgctt attgaaatta tgatataatt gaaatcaatc gatataagct tgccttgcat
    49201 gcttgttatc ccttaaaagg aggaattaca tgtctttaaa aaaatatagc ttcctcagca
    49261 ttttttgcta tggtctaatt tttatctcac ccttgatcct agcttcgata ggacttgtaa
    49321 aatctacgtc tgaattgatc acagcaactg cagtcatgta tatactaggc gccgttgtcc
    49381 tagctatttt ttattttaag caacgtgaac ccttagcgat cgaatcagcg gtaaaaaaag
    49441 cttctgctcc aaagattgtt atttatggat tggttggaat ctttgtcgca ttgattctgc
    49501 aaagcatcgc tgtcatgtta gaatctgtat tgtttggcaa agcaacccct tccgagaata
    49561 cacaaaatat catccagatg atcatggaag cacccgcttt tattttggcg acaactgttg
    49621 ctggacccat catggaagag ttcgtattcc gccgcagtat actggggatc atcagtcgat
    49681 attcaaattt ttgggtcgga gcagtgatca gctctttgct gtttgcgttt gctcataatg
    49741 atggtcatct gctaatctac tttttcctag gtttcttctt cagcctagag tacaaagcaa
    49801 ctggtcggat ctggacatcg atgatcacac acgtaggaat gaacacatta gttgttcttg
    49861 ttcaattagc tgtccaaaaa gggctagtat aaacatgact ataaatactc ctgtcatcct
    49921 agattggtga ttttcccaat ctaaagcgac aggagtattt ttgtttttta gtcgttcatc
    49981 ttttctgctg ctccatcatt ttttgtctgt ctttcctttt tgcagtttgc agaatctatt
    50041 tttttcaaaa atgggaaata aatgaaaaaa ctaattgaca acacgatacc ttgtaaaatc
    50101 gctgcaggca ctccgcctac taagaaaccc gagaggatcg gcggtgttgt ccaagggact
    50161 tggactgctg taaataaagg aacgaatcca aaatataaag cggaataggt aatcaatcct
    50221 gaaacgaccg gtgcgaaaat aaaaggaaca gccatcatcg ggttcatcac gatcggtgtg
    50281 gaaaaaataa ttgattcatt gatgttgaaa aaggctggta aaagagcaag atttcctaat
    50341 tctctgtatt tcttcgattt cgcaaaaacc gtcataaaaa atacagcccc taacgtcaat
    50401 ccagcacccg taaccgtcat gaactgatcg agaaattgct gagtaacgat atgtccgcca
    50461 tttgccaccg tcaactcttg tcctgaggct aagatttctg catttgctaa tgaattcgct
    50521 tgcaagacgg gactaaccaa cccattgacc atcgcagatc catgaagacc aaataaccat
    50581 aaaaacggaa caaaaaaacc taataaaagc acaccaaaca acgtgtctat gaacgattga
    50641 atgggaagct ggacatatgt ccatactcct tgaacaacag tcattctgaa caaatgttga
    50701 aaaaccgctg aaccgataag cgtaaaagtg actataacaa tgattggaat caatgaagta
    50761 aaagactgcc aaacattttc aggtatcttc tctctttgct tccacccttt cgcaagtctt
    50821 actaaacgtg catagcccca tccgatgatg agcccagttg taactgctcc tagtatccct
    50881 tcagcacctg tccagacagt atctatctga gtatttagtg gctgaataag cagtagataa
    50941 gcagacaagg ctgttatgcc gactggtaag cgatcgatgt cttcttcttt tgcataagcg
    51001 tatgcaatgg caaaaacgat ccaaaaggct atcacatcaa atgtagcctg gtatacttgt
    51061 gtaaaataca tagaaaatcc tgttttgtct atccactgag cgatgtaatc cacaggaaaa
    51121 tgagcaaata agaaaaacag cgagccaaca ataattattg ggatcgtgta agtcattcca
    51181 ttacgcaaag cagttaaggg tctaagattc acaacagatg ttatcattgg taaaaaggca
    51241 cgatctaacc actctttcat ttcttatctc cttcaacttc tatttttatc aatcagtttt
    51301 cttaatttaa ctatacccaa tgatcacgaa ccatgaaagg aatgcgcact gagcttttca
    51361 aaaatcggat tctttgacga atattcagca actgcttaca atggacagga ataaaaaagg
    51421 aggtttttta tgaaaattgc actcattgga gctactggcc atgcaggttc atttatttta
    51481 gacgaagcat tgtccagaga tttagacgtg acggcaatcg tgcgtcatcc agaaaaattg
    51541 ccatcagatg ttccgtttat acaaaaggat ttatttgagt tgacaactac tgatcttgca
    51601 tcttttgatg ttgtcgttga tgctttcaac gctcccaaag gaaaagaaga aatgcatcaa
    51661 acttctttgt cccatttgat tgagatgctt gaaggaaccg atacacgctt aattgtcgtt
    51721 gggggtgcct cttcgttatt cttagataca gaaaagacga ctcgtatgat tgaccaagta
    51781 cctaaaaatg cacccttcta tccaacagct ttcaatatgt acgaaggatt gttaaaattg
    51841 aaacaatcta aaaatctaca ttggacttat atcagtccag cttctttatt tgatccacat
    51901 ggcaaacgta caggtactta tttgttaagt gatgattatt tacaaagaaa cgctgctagc
    51961 gacagtacga tcagcatggc agattacgcg attgcattag tagatgagat actggatgag
    52021 aaacatgaaa agcagcacat cagtgtagtc agtcgataat acggttattt ttttaatatg
    52081 ctaaaaaaat aaaaatagaa gataaaacca accctgattg attttatctt ctgcttttta
    52141 tatttttatt gattgaactg tttaaatcga aaatagctca gttgcttcat ctggatctgt
    52201 atcatagatt tcaaaatcat gtccaacgcc aaaatctttt tctttcaaaa cattttccat
    52261 tgttaaatga gcaagttctt tcatattgtt ttccttgcta agatggccaa gatagattcg
    52321 tttggtccga ttaccgatca catcagtcat gacaagtgca ccgtcttcgt tggaaagatg
    52381 tcctctatct cctaaaatac gctgttttaa attccacgga taaggtccca tgcgtaacat
    52441 ctcaagatca tgattacttt ccatcaaata accatcggca ttttcaatga cacctcgcat
    52501 ataatcactg caatatccgg tgtccgtcaa catgacgaat gaccgatttt ctttatggaa
    52561 acgataaaat tgcggagccg ctgcgtcatg ggagacgccg aaactctcaa tatcgatatc
    52621 gccgaatgtt ctgactttcc ccatctcaaa tagatgtttt tgttccactg gtacatttcc
    52681 aatcagtggt tccatcgctt cccaagtctg ctgattggca aaaacatcca aatgatactt
    52741 acgagccaag acacccacgc catgtatatg atctcgatgt tcatgcgtca caagtattcc
    52801 atctaattgg tccggtgtcc gatcaatttg agccatcaag gaagtgattt ttttaccgct
    52861 aagtcctgca tcgaccaaaa gccgtttttt ttcactttcg atataaagtg aattacccga
    52921 acttccactt gctaggatac tgattttaaa agctggtttt tcttcagcca tttgactcct
    52981 acttcccttc ttactttgta aacttttttc attatactcg cttttttatt gatcttccac
    53041 ttttggtaca gtattgtttg tcacgatcgt attgctgaaa gcgttgacgc tctcaatttg
    53101 gaccacttta tcgcttgttt cgatcgctac atgccaaaca ggaacataca catttttttc
    53161 ccggactttc agaatacagg aataagctag ctgacgccat aaaatttttg atcctcttgg
    53221 tattttgtta ttgatgtaca atgtattgat tgcttcctct tccgtataca gttccgtctt
    53281 ttcgcgcagc tgctcgatat cagataaatg cgtctgcatg tatttcgtga tgctataatc
    53341 attatcgttt ttttctaaag aaagaacgat ttttgctgta tcatcattga atgggatgcc
    53401 ttcatactct tggcttgctt ggatttctag tggttcttct tctaaatgag aaaagttttt
    53461 cgtgtacaca taatcattac cgaataaaat attgtctttg ttagataaaa aatcttccaa
    53521 ggaactacta attttatctg gatcgatcac gttcttttca gcatctgaac tggataaaga
    53581 tttcgtcaaa acatcaccgt ctaaaaacac accacttgcc agcaagccgc ttttaccagc
    53641 cttgcgataa ttcgctaatg aagtgctaag attggtctgc tccgcgctaa gataatagcc
    53701 ttgcttgttc tcagacgaaa tcttccccgt gtaagtgata tcgtcgctag ccagacgttg
    53761 ttggattgat tcagtctgat tagagcgaat gacattgttt tcttggtata ccgcgtcatg
    53821 ataactgctg aataaaaaca cattcaaccc taaaaaagcg acgaaaaata tccattcgat
    53881 ttttttgaaa tccaattaat tcgcctccaa tccaggtaat ttttccagaa ggtcgttagc
    53941 tgaataccag ttatctttat atttcacata ccattcaggt aagagatcaa cgacacgatt
    54001 cgtttctttg acattttgcc atgtatagcc aacgatcact gaaccaatct tgttgctatc
    54061 tgctccctta gcttttaact gctggatgat ttcattcgta cttgcaagtt ctacttcttc
    54121 gtctgaaggt atcggcactt gaatcgtatt caaactggtt tggatattca cttgcacaga
    54181 accattcgtt tcaccgccaa cttccacacc aatctgtcct ctgctgtctg tcccaaaaac
    54241 cgggaagcct tccacgaata tccgataatc gatcgtattg tcactgcggt caaaatatct
    54301 gaggttccct aaagaactgc ctaatttgct aatatagggg aaactttcag aaaatacact
    54361 agcattttct tttttctctg gcagctctcc acgaaaatca actacttgcg tttccgaatg
    54421 gatagacatt gtttcattcc caccgtaaaa aatcaattca ttgctttcat cattattttt
    54481 cacgctatct ggtttctgga aaaaagcatt tctaaaaagt gtatagggtt gctgtgacag
    54541 gatataacta tacttcttca gtttgatcga atgtttcgta gcatattgcg tgtcgatcgt
    54601 cgatggttct gttgtcattt ctgtccattt tgtgtctttt gctgttaatt ctttattgat
    54661 atctgtccaa ttcaacgaaa tatttgcttc atatacgaga tggttcgaat aattcaaaaa
    54721 tcggattttt ttatttcctt gatcgaattg tattctagta aaatacatat tttcgctttc
    54781 ttttgccaag ttcgacacat ctaaatctaa atcaaatgct tccttgtatt ctcttagcaa
    54841 aaaaggcgca ttataggcca actcaaaacc agagttcaga tttttcacct gttcaaactg
    54901 tgatttgtct cctgaaacta cttcagaaag ctttccaaat cttgctttat cgatgatcaa
    54961 ttgcaatcgg tacacgagat tttcactgtt ggtttcttgg atcattcccg aatggtgcca
    55021 tgtaacatga agcggaagaa agacttcgga agtttttcga ttgctttgag actcgatcat
    55081 ttgagtgttt gtctcatcta cgttgattga actttttcct gctgggctca gccagattgc
    55141 ataagagaag tatatgctta acgcaaccat caaaatgagt cctatacgaa cgactttttc
    55201 agagattctc attcccacca ttcctcctca taaggttcat atggcagcga gatataaaaa
    55261 gtcgaccctt ttccttcctt gctctctgcc caaatagcgc ctcgatgcgc cttaatcact
    55321 tctctagaaa tagctaatcc aagtcctgtc ccaccttgtg ctcttgcacg tgctttatct
    55381 actcgataga accgctcgaa cactcggttc agatcttttt taggaatccc caatccttga
    55441 tcggtgatac ttaaaatcac gttattatgc gtttctaata agcgacaagt aatcgttccc
    55501 ccatctggtg aatacttgat cgcgttattc atgatattat cgactacttg gatgatttta
    55561 tctgtatcta cttcgaccca aagatctctt tgcgtaaatt cacgacggat cttataattt
    55621 ttttcctgat ttcccaccat catatcaaac cggtcaagaa caaaattcac taactcgttg
    55681 aaattgacat attctaattg aagctgggta ttacctgtat ccatgcgaga tagatttaag
    55741 aggtcattga tcattcgaat cattcggtct gtttcatcta gcgttacctt caaaaaattt
    55801 ggtgctactt cctcgtcttt ccacgcacct tcgctcaatg cttcgatata actacgcata
    55861 cttgtcaacg gtgtacgaag ttcatgggaa acattagaga cgaattcacg acgttcccgt
    55921 tctgtttttt cttgttctgt cacatcatgc aagacagcta ctaatccgct gataaaacct
    55981 gattcgcgac ggatcataga aaagtctact cgcaagatca tctgatcact ttccaatgta
    56041 ctggttgaac ggtcaagtac catttcgttt ggatcttcta ataatttccg caacgtatat
    56101 tcttcttcga tatctaaaag tgtcaaaatc gattgtccga ttgcttcctc gtttttgata
    56161 tctagcaagg aaacagccat atcattgatc gtaatgactt tacccctgcg atctgtcgca
    56221 atgacgccgt ctgtcatatg ggatagcacg ctatccaaac gattgcgttc agcttccatt
    56281 gtatcttgag cttcttcaat acgttcagct aactgattga aggtatcagc cagctgtcca
    56341 agttcatctt gtccatgcac tttgactttc cgactgtagt ctcctctagc gattcgaatg
    56401 gcttgttctc tcatttcacc gatcggctgt gtaatcgaac gagcaactaa aacagatacg
    56461 atcattgaaa taaatgccgc aattagtgag gcagtaaaga aaatgactgc tgtgttattg
    56521 atttccgaat atttttgttc gatattactt ttgacgtaaa gagccccgat aacggcatcg
    56581 ccggtcgggg acaggatcgg ttgaacattg atattcaccc gtttatcgtc gttatctaaa
    56641 gcaacataac gtttagtcgt gaaatcattg atatcaacat aatcattttt ctttcccaca
    56701 gcgctttgtt cattgacatc ggttgttcct cggatgatcc ctttttcgtc aacgacccgt
    56761 atttcgatga tatcgctagt cgcactgttt tcaataaatc ttttgatatt cgcatttacc
    56821 tcttcatcat ctgcattatc ttttcgattc aattccgggc tgattgttgt tgctaatgat
    56881 tccaccgttt gattcatatc tttaataaat gtattgatcg tggaacgttc taaaccacgt
    56941 ataaagtagg caccaataat ttcgatcgag atcaataaaa tcagaataaa ggtaatagcg
    57001 atcttaaaat tgactgatcg aaaaaagcgg acttttcttt tcatccaatt actcctgttc
    57061 tgggttacgc aaatagtaac cgacaccacg acgtgtcact aaataatttg gatggcttgg
    57121 attatcttcg atcttttcac gcaaacgacg tacagttaca tccactgttc gtacatctcc
    57181 aaaataatca taaccccaaa ccgtttgtaa taaatgttct cttgtcatca cttgtccaag
    57241 gtgcttcgcc aagtaaaaga gtagttcgaa ttcacgatgt gttaactcga ttgtttctcc
    57301 tcgtttcgtc accatgtaag cttctggatg gatcgtcaaa tcaccaatcg tcaattccgc
    57361 aggtgctgcc tcttctggtt ccttcgcagc cgtggcaccg cgacgaagat ttgctttgac
    57421 acgtgcaact aattctcggt tggaaaatgg cttggtcacg taatcatcgg cgcctaactc
    57481 taagcctagg actttatcaa tttcagaatc tttggctgtt accataatga tcggcatatc
    57541 ataagttttg cgtacctcac gagcaacttc taagccgtcc attttaggta gcatcaaatc
    57601 aagtaaaatc aaatcaggtt ctacctcagc aactttttcc aaggcttctt ccccatcata
    57661 tgcagtataa acgtcatagc cttctttggc taaattgaat ttgacgatat ccgaaatcgg
    57721 cttctcatca tcgacaacta aaactttttt cataaagagc cacctcttat atattattgt
    57781 cataccttct cattataccg tatttctgct tttgtttcat ctttgcctat aaaacaaaag
    57841 agaaaattaa aatgaaagtg caaaatactt tattattttt tgttctaact tcaataaaaa
    57901 aggaaaacac tgattttcac ctcagtgttt cctttttttg atttatcctt ctaaaacttg
    57961 tacaccgaca cccaataatc ccggaccagt gtggactact aatgccggag aaatctggcc
    58021 aaagtagatt tggtttgctt gtgggaactc tcttttaagt ctcgcttcca tttcaattgc
    58081 ttcttctttc gcatccccat gggcaacagc taagttgaag acctttgcat taccgatttt
    58141 ttctttgacg taagcaaccg ttttatccaa acttttttta cgtcccctag cttttcctac
    58201 tgtgtaataa atcccttctt cattacatga gatgattggg ttaagcttta aagcggttcc
    58261 tacaatagaa gcaactaaac cgatccgtcc acctttttga agatattcca atgtcgcaac
    58321 attaaagaaa acttttgttc tttcgactaa ctcattcaga ttactgatca gttgatccca
    58381 ttctactcct tcttccagcc attttgctgc ttggatcgca gaaaaacctg caccaatacc
    58441 aatatttttc gtatctagta catatgcttc caattcttct tgctgttgtg caattaaacg
    58501 aaccacatta tatgtcccgc tcaatccact ggaaattgtt accgcaagta ccttttcata
    58561 accgtctttt ttgatttgct caaagatttc tgtgatcgac tcaccatccg gcaaagatgt
    58621 accagggatt tcctctggca aacgttgata gatctcttca ggggtaatgt caattttatc
    58681 tgtatatacc tgatctttat aaataatttt caatgggatc atatacatct cgtatttttt
    58741 tatcaattct tctggaacat ccgtacctga atctactaaa attgcgattt tattgttttt
    58801 catttgtttt ctcctctttt aaatattcgg tttctagaac aatcgttttt tccgcaagaa
    58861 gtttcattgc aaacgataaa gttgccgctc ttacagcaat atattctaca ggggttgcct
    58921 ggtcgaattt ttgcggatga gatttacctt gtgctaattg gctgaccatc cacacagctg
    58981 cttcttgttc atcgcaaaat agattatagg cttcacgaat tcctactgtt tttccttgga
    59041 acaatatccc ttctttgatt tcaggaatag tcaatacttg tttcaacgta gtgattgcaa
    59101 gtaaaaatgc tacgtgttct ttgttatatc tttttttaac tggtgctggt atcaaaccta
    59161 gtttaacgta attgtttacc atagaagagg taagcaatgg atgcttttct ccttgtatca
    59221 caggtgaaag ataacgatca actaacgttc tgacttggtc catataaagt tctaagtcag
    59281 ggagttcttc ccagtgaggc agacggaatg tttctagttc cttcccccac tccattaatt
    59341 gctgacgcat tttttccatc ataaccgctc cttttttcat ttcataaaca tgatatcaga
    59401 cttatgataa acattcaatc tagttgcttt aactaggtga tttgattagc gggattccat
    59461 gaaaacaaaa aacaagaagg ctaagccttc ttgtctttta tcgttaagaa caggagaccc
    59521 gccggggaga cggcgggaaa ggagtaaaaa atgaaaaaag tgttagggtt tgttctcttg
    59581 caagaacttt gtttgttggt atgcttatat aatagcgagc aaatgtgaat aatctatgaa
    59641 tgatttccta taaggaagta aagatttttc tgattttctt taaatgtagt cttgcatttt
    59701 aaaattctta gtgctactat tattaagtac tttttgtacg ggccgttagc tcagttggta
    59761 gagcagctga ctcttaatca gcgggtcgcg ggttcgagcc cctcacggcc cattgggtgc
    59821 caaacccacg gaacaggtaa atgttggtgc gaaagcattt cgaaaacatt tacgctgttc
    59881 tttttttatt tttcaaaata actagggctt tttattttta actcaaagtc cactgtagcc
    59941 ctttggactt tgagttaaaa aagaagcata attatgaaca gtaaagtttc taatataaca
    60001 ataattcgag aagctttgca aaatcatgct gccaatgaac tctctaaaca tataggatta
    60061 aatctaagta ctataaaagg ttaaaaagtg aagaatattt aatagaaaaa ctaaatttac
    60121 ttgctgcttt ccccttttcc attaatacaa caatcagaga gtgtcttttt ttcgaaaaaa
    60181 ttagaataaa taaaagacac gtagtttttt tatctacatg tcttccatcg actacaagtt
    60241 atcatttctc aaaacgtatt tagcttttaa ttgattaatc gtttcacgtt gtctacacat
    60301 tgcctaatta agattttctt attagaagca tcaatcccgc aataatacct aaaactccag
    60361 gaattaccca caataatgtt aaaagaaaaa atggaataat agataaaatg agtaaactaa
    60421 taccatagac cactgttttt tgattttttc ttactaaaaa acctattatg aaaatcatta
    60481 tcgaaaaaac tagggtaatt cctccaaata aaacaacatt cccgcttaga ttgactaaca
    60541 tatctatatc cttactggtt agttctgtag tatttaaagt agttgaatca atagaagata
    60601 gaaacatacc acccatcaat gctaaaagac tacataaaat ccctgttatt ccactaatta
    60661 aaatcaaaat aaactctgtt tttctcttat tcatttaatt ctctccagat taagtgtttt
    60721 agaattagaa attttttgac catagttaat agcttctaat gaacgaataa caaccactga
    60781 cgtgttagaa aaataatccc caatatgttg tttcttgggc gtgaaagcag ccaccaaata
    60841 cccaatttga aatacaaaat tttttaatat aaacctacat atacactcac gaataaagat
    60901 agtttgccaa cttagctctt tttcctcaaa gctcactact cttatcccaa aaatcatttt
    60961 cccaattgtt tgtcctgaat tcagcttagt caaaagtaca aaataggtta aataaatagc
    61021 taatgacgct ataccataaa aagtaataat ggatttgtca gattccagtc ccatgatttt
    61081 gtaaaagaga cctatagtag catgggtgat gatgctaata caaattaaat caataagaaa
    61141 agcaaaaaat cgtaaccaaa atcccgcaaa tacataatta ggcaaagttt caatgccact
    61201 cttcttattc attttatagc cctccatagt aatacattgg ttttggagta tcagaaaatc
    61261 caagtttttc aaaaactgaa attacacgat ctgatgtagt tgcctttagc ccttgccatt
    61321 cagcaatctt attacctaac caagaagaag caaagccagt tgtgtcattt ttatattcta
    61381 taaccgtcgc atcagttaat ttcttctctt tttttaggga atctaatgca tcttcagagt
    61441 aaccaatttg atccaccaac ccattttcta ctgcttggtt accatcataa attcttccat
    61501 ccgcaagttc tttcactgca ttagtatcca tatttcttcc ttttgctaca acattgacaa
    61561 aacgatcata agcactcatc acaaattcct gtataacttt attctcttcc tctgaaggtt
    61621 tgtgttgagg tgacatcata tcttttaatg caccactttt atacgtcgca tcagttacgc
    61681 caagtttttc taataagcca gaataattta aaccagaaat aatgacacca attgatccag
    61741 ttgttgtttc ttccgtagca aatattttat ctgaaccagc agaaatgtag taccctccac
    61801 ttgccgctgt atttttaaat gcagtataga taggaatatc tagcttttta atttttgcca
    61861 tttctttagc aatctcagca ctttcatata ttcctccccc aggtgaattt acttctaata
    61921 acactccctt aaccgctttg tcttcttgaa ttttctttag ctgtgttaaa aaattctgat
    61981 ggttatattg ttccctacta aaaagattgc tttcacctgt atctgcaata actccattga
    62041 cggatagttt gacaatcttt ttatttgatg cgccttcttc taacgtttct tctgtgattt
    62101 cgttagatcc gtaaaaaatc ttatttattc ctgttagggt tgtatttgat gcttcctctt
    62161 tatcttttcc tggaattagc gcgacgataa tggatagtaa caataatccg cacgctactc
    62221 ccacagcaat ccatcttctt ttattcatat aaactcctcc tatattctta gtaaaaataa
    62281 ttatttttta tttagaaaca catcgacaat ttgttgccaa tatgtttttt ctcctacaat
    62341 taaagacaac tctccagtta atccataacg aaacggaaac gattgagttg tttttaacgt
    62401 tcctttcact gcataaaaaa cacctttctc agtggcagta gaattttctg aaatttcatc
    62461 taaagttccg tcgatcgtaa tcggagcccc acctttttga tccaatttaa aatgaacctt
    62521 catcccttct ttaatatagg tactttcatt cgcaggtaaa agtgctgtaa atttcatttt
    62581 tgatttttcg tggatcggat aaatttctgc aagcactgtt cctttggcta gttctgcttg
    62641 tccctttgtt tcttcattta aatgaaccgt tccagataca ggagctttta gtattccttt
    62701 tgaaagttga tcgtccaaac ttttgataac tgactggttc ttctcttgtt tttcatttag
    62761 ctctgtaact gtttgtttta cagttgttat tgcttgttct agctcttgct ttcctttttc
    62821 cgtttgacta attctgtcat tctcagaagt agttggttta actaatttag ctttttctga
    62881 ctgatactgt tctacttctt tttttagttg ctcaatttgt tcatttatgc ttgctgaaat
    62941 tgtcagtttc acttgatttt tttgatcatc agaaacatta tttagttgtt cttgccaatt
    63001 ctcatagttt gccatcattt cttttgaaaa atcttttaat gattgattat tactccaagc
    63061 tacctgtact tgttgccatt cttgtaattt actatctgaa ctctcaattt gtttttctag
    63121 ttgtcttttt gtcttttcgt atacttctaa ttgcttttga tcatttaatt cactttgctt
    63181 caaagcgtag cggagtgatt ctttttctga caacatgctc tttaattgat tactgtagcc
    63241 aaaactgtca tccgttgaaa acaaattttt tcctttactt atactttcaa taaatagctg
    63301 agccatcttt atttgttgag taatacgttg gttttcttgt tctatctgag ccttttcatt
    63361 ctctattaaa gaacaatcca atctaaccaa cacatcgtcc ttatgaacaa attgattttc
    63421 ttttaggaag ttttccatta ttttagcttc taatggcact tgtaacttct ctattttttc
    63481 ggggttcaat tgagccgttg tccgaataac aacctctttt ttagcaaagg ttaaaaacaa
    63541 tccaataata cataaaaaaa gaattacagg gtataacacc caacggtaga agctatgatg
    63601 ttgtttagta tagatactag aatgttcgaa ccaattatta ttctgcataa attgtttccc
    63661 tctcctagat ttcccataat ttttgataga taccatcggc aaaacgaagt tcatcgtgcg
    63721 ttcctttttc taccaaatgc ccttcatgga gaactaaaat ttgatcacat gcttttgcta
    63781 ttggtaaatg atgcgcaata aaaataatcg ttttttcttt taaattgagg agataattca
    63841 taattgcatg ttctaacaag gtatctaatc cactagttgc ttcatctaaa attaatatgt
    63901 ccggattttt taataaagcc cgtgctaagg ctaatcgttg tcgttgccct cctgaaagat
    63961 tatttccacc ttcttccaac aatgtctcgt aacgtaatgg ctgttgatta ataaattcat
    64021 ttagttggac tatctcacaa acttctatta tttgttcgaa acttggtggg ctatctaaac
    64081 cgaatataag attctcaatg attgttccac taaagaaaaa tgactcttga ggcaaatatg
    64141 tcactcgatc gcgtaatatc tgaaaaggaa tgtctaagtg attaatgttt ccataatgga
    64201 tcgatccttc tgatgcttca taaaaacgaa caaataactt tgcaagagtt gattttccag
    64261 aaccactaac tccaactata gccgttttac tgtgcgaagg aattgtacat gaaatttcgt
    64321 tcaacgttgg ggccttcatg ctatacgaga atgaaacgtt ttttacagtg atatcttgtt
    64381 gaaataattg ttcagaaagc atatattcaa aagactggtt cgatttttct gaatcaatcg
    64441 cgaaaatttc atttaaacga ttatttgcaa cttgagccgt ttgcattttc acttgtaaat
    64501 taataatgtt ttgtaaagga tctgtcaaaa atactagtaa agcattgtat gtgataagtt
    64561 gacctagact aattctatta tccataacaa aataagaacc tagccataaa attaatgcac
    64621 tgctaattaa ttgaatcaaa tgtttaattc cttgttgaat attatcaagc gtaaccgtac
    64681 gaaatgattt tttcattaat ttaacaaatt catggtctat acggttatat actttctctt
    64741 caccgctata tgctttaatt gtttctattc ctttaagact ttctatgata ctagaattta
    64801 cagctgcacc ggctgccatt tcttccctgt tcgatttttc atagcttttc acgaaagcga
    64861 atattgcaac tacataaaaa ggcaaagagc atagagtgat taaaaacaac gtactattct
    64921 gaatagctaa cgtaacccca acaagcaaca ccataccaat atctaaaaat attgataacg
    64981 tagcacttgc taaagcatca ataatcttac tggcatcaag aaaacgagaa ataatttccc
    65041 ctgattttct cgtagcaaaa aaattcattg gtaaagttaa cacatgtttg aaatactgaa
    65101 gcataattgc catactcatt cgctgtccta aaataataag aagataacta cgactatatt
    65161 caaacaatac ccgaaataaa tagacagcga tcaagccaat ggaaattata tttaaagttg
    65221 aacgtgcttg attagggatg aaaaaatcaa gaataccttg aaaataatat gagcttccta
    65281 tgccaaaaaa cgtaatgaaa atcgatgcta aaacgatgtg gaatactaat cctttttgtt
    65341 tccaaattat aggcaaaaaa gaacttaatc cagctacttt ttctttaata ggaatataag
    65401 tttctctagg cataggtaat aaaagaatac ctgtccattc tttttgaaac gcttcaatcg
    65461 tttttctatt ttttccatta gcgggatctg caatccatag tacgtttccc ttcgttttat
    65521 aaattacaac gtagtgcata tagctgttat caaccaatat atgtgcaatt aatggtaaga
    65581 taagatctct ttctttccag atctcactat ctgcttgaat agccatacaa tcaaaagaca
    65641 atttttcaaa tgtctttttc aatccaaatg ctgaagtacc ctctaaatca gtcccagata
    65701 ggtcccgtaa tttatgaatc gggatatcag ttttaaaata ttttaaaatc atcgaaaggc
    65761 aagcaacacc acaatctttt tcatcttgtt gctgcacaaa aggaaatgat tttatcactt
    65821 atctaacaca actccttcta aaaaattttt atagaaaaat tctcaatata gctttaatac
    65881 agtgaaaata ttgtctcata attccacaaa aactttgaaa acagttcttg aacactaact
    65941 ttttcattcc tgaatcaaat ttattttgga aattttacta ttcaagaata aacttgataa
    66001 gtttcaggaa gatttttact gttaatcaaa tacgtatgtt acagtagcac cgtaaaaaat
    66061 attatttaaa gaagcgtgtt taaacatgca aaatgtaaag gaactaagta ttgtggaaat
    66121 gcacaaactg ttggtggagg caataatgct tggggaaaat tggggcaagt tgtaggtgga
    66181 cttaccacag gggcagtagg tggtgcaggt ttaggaacag caatttgcgg accagcttgc
    66241 ggtgttgttg gagggttata tggagctgtc gctggaggtg ctgcagctgg ctgggatgct
    66301 cgaaaaaaat aaaaaaggag aataagtagt atgcatatta aaaacacaaa aacaacattt
    66361 atattatctt cagaagagtt gaaaaatatt caaggtggga gtgccgtggg agttttaggc
    66421 actacttttt ctggggcaac agcaggagta aaactttgtt cagccggagg accttatgca
    66481 atagctgctt gtggtgtagg tggagcttta ttaggtgctg gattcagcat gtggaccggt
    66541 gcgtaaacaa ttaaaaaata tcaaacctca agattggttt gtgtcgatta cgaacatagg
    66601 tatgttcttt atcttttcaa aagtttggaa tggacagaac tttttactaa agcttcttgt
    66661 gctagttttt ataattatat taaattttta tcttttatta aagtcagata aaaattcttt
    66721 ggaaatgtaa tggtagagat atttttacaa aaggacttgc agcgctgtag ttggtgctgc
    66781 aggaggacct atttcggccg ttacaggagg tattggtaat gtacttgtcg gatgtgcatt
    66841 aaagcctgtt cctgcaagtt aaatttataa aaacaggaaa gtaattatct caaatcctat
    66901 caagtacaat cataggattg cacttgacag gacaaatttt ttaactaaaa aatgaaaaac
    66961 actttctaaa aattagtaga atttgccaaa tctttcgcat cttccaccat acatttaatt
    67021 ttaattcccc tttatggtac ttaataaaaa caagaaaaga actattcatt tggccctttt
    67081 ttggttccag accatagaaa tattcctcca gtaactaata ttgctgttat gcacgtaact
    67141 aataacagct ataaaaattg gtacaacttt aataggattc agaaaaattt gcactagtga
    67201 aggaatctat tttattagaa aaatgcaatc tccctaaaga aaaaaccact aaacagtgct
    67261 ttctttcaac ttctccttaa ttttttgtgc tttccctaaa gtaaagtttc tggccaactc
    67321 tgaatcaaaa tatagtgaac gttttttaaa atctatttct ttaacgttaa agatatttac
    67381 taaacacgct cgactaattc ttgttaacat aggatatttc ttttcaagct cactaattct
    67441 tccataaaat tcgtactgcc catctttagt acacaatgat aatctatgtg gtaattttga
    67501 agcttctaca aaataaatgt catttatatc aaaagtaaat gtttgagaac ctatggaaaa
    67561 aacaaatgct tgattcgtaa cctgttttgt tgcatctatc ctttcttgcg ctaataacaa
    67621 taactcaaca atctcgtttc gatactcatc tagtgtttga tcttttgtta caaatcctaa
    67681 cgtttcaact cttcttttta ttgttacggg taacatctca tcatgagtag ttgtaaaaat
    67741 gatttttgct tgaacatcat attttctgat tacttctgct aattctatac cgttaacttc
    67801 atgatttaaa tcaatatcta agaaatatat tccttgcttt ggtcggaatt gtttgaggta
    67861 ttttttaact tctaacggac tttgtgtttt caatactatc ttaaatactt tatcgtgaaa
    67921 aagaatgaaa ttatcaataa ttcgttctaa ctgatttaat tgtataattt gatcttcaca
    67981 taatattatt ggataactca taaatcctcc ttccctcaaa acaacaaaat aacttgagta
    68041 gtaaattgat acggatcgtt ttgatagttc acaaacatat tgggattctt tttattgatt
    68101 tcctctatac tagataaacc taacccttga tgtccctttt ttgttgttat tccttttttc
    68161 attagagtat ctatagagag tagtatctct ctacaactat tcgatatcga aatttctatc
    68221 tgtttatcat ctcggtaaat agctagagac agttctctat cttgactctc tatagatgct
    68281 tcaattgcat tatcg
//
LOCUS       DACBYO010000005        59771 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.005, whole genome shotgun sequence.
ACCESSION   DACBYO010000005 DACBYO010000000
VERSION     DACBYO010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.005"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            9..722
                     /locus_tag="IVD26_000281"
     CDS             9..722
                     /locus_tag="IVD26_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078288.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(837..1847)
                     /locus_tag="IVD26_000282"
     CDS             complement(837..1847)
                     /locus_tag="IVD26_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAP6078289.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(1884..2366)
                     /locus_tag="IVD26_000283"
     CDS             complement(1884..2366)
                     /locus_tag="IVD26_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAP6078290.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            2516..2884
                     /locus_tag="IVD26_000284"
     CDS             2516..2884
                     /locus_tag="IVD26_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAP6078291.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3349..3801
                     /locus_tag="IVD26_000285"
     CDS             3349..3801
                     /locus_tag="IVD26_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6078292.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(3939..4790)
                     /locus_tag="IVD26_000286"
     CDS             complement(3939..4790)
                     /locus_tag="IVD26_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAP6078293.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4803..5588)
                     /locus_tag="IVD26_000287"
     CDS             complement(4803..5588)
                     /locus_tag="IVD26_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6078294.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            complement(5940..6881)
                     /gene="ribF"
                     /locus_tag="IVD26_000288"
     CDS             complement(5940..6881)
                     /gene="ribF"
                     /locus_tag="IVD26_000288"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAP6078295.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(6885..7808)
                     /gene="truB"
                     /locus_tag="IVD26_000289"
     CDS             complement(6885..7808)
                     /gene="truB"
                     /locus_tag="IVD26_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAP6078296.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(8176..10538)
                     /locus_tag="IVD26_000290"
                     /pseudo
     CDS             complement(8176..10538)
                     /locus_tag="IVD26_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            10986..11159
                     /locus_tag="IVD26_000291"
     CDS             10986..11159
                     /locus_tag="IVD26_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6078297.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(11316..11663)
                     /gene="rbfA"
                     /locus_tag="IVD26_000292"
     CDS             complement(11316..11663)
                     /gene="rbfA"
                     /locus_tag="IVD26_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAP6078298.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(11690..13996)
                     /gene="infB"
                     /locus_tag="IVD26_000293"
     CDS             complement(11690..13996)
                     /gene="infB"
                     /locus_tag="IVD26_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAP6078299.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(14009..14320)
                     /locus_tag="IVD26_000294"
     CDS             complement(14009..14320)
                     /locus_tag="IVD26_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAP6078300.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(14317..14610)
                     /locus_tag="IVD26_000295"
     CDS             complement(14317..14610)
                     /locus_tag="IVD26_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAP6078301.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(14632..15807)
                     /gene="nusA"
                     /locus_tag="IVD26_000296"
     CDS             complement(14632..15807)
                     /gene="nusA"
                     /locus_tag="IVD26_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAP6078302.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(15830..16303)
                     /gene="rimP"
                     /locus_tag="IVD26_000297"
     CDS             complement(15830..16303)
                     /gene="rimP"
                     /locus_tag="IVD26_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAP6078303.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(16448..20806)
                     /locus_tag="IVD26_000298"
     CDS             complement(16448..20806)
                     /locus_tag="IVD26_000298"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAP6078304.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(21018..22727)
                     /locus_tag="IVD26_000299"
     CDS             complement(21018..22727)
                     /locus_tag="IVD26_000299"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAP6078305.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(22795..24063)
                     /gene="rseP"
                     /locus_tag="IVD26_000300"
     CDS             complement(22795..24063)
                     /gene="rseP"
                     /locus_tag="IVD26_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAP6078306.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(24224..25024)
                     /locus_tag="IVD26_000301"
     CDS             complement(24224..25024)
                     /locus_tag="IVD26_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAP6078307.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(25021..25833)
                     /locus_tag="IVD26_000302"
     CDS             complement(25021..25833)
                     /locus_tag="IVD26_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAP6078308.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(26028..26585)
                     /gene="frr"
                     /locus_tag="IVD26_000303"
     CDS             complement(26028..26585)
                     /gene="frr"
                     /locus_tag="IVD26_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAP6078309.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(26588..27310)
                     /locus_tag="IVD26_000304"
     CDS             complement(26588..27310)
                     /locus_tag="IVD26_000304"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAP6078310.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(27446..28327)
                     /locus_tag="IVD26_000305"
     CDS             complement(27446..28327)
                     /locus_tag="IVD26_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAP6078311.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(28426..29208)
                     /gene="rpsB"
                     /locus_tag="IVD26_000306"
     CDS             complement(28426..29208)
                     /gene="rpsB"
                     /locus_tag="IVD26_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAP6078312.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            29567..30046
                     /locus_tag="IVD26_000307"
     CDS             29567..30046
                     /locus_tag="IVD26_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAP6078313.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            30263..31354
                     /gene="phnW"
                     /locus_tag="IVD26_000308"
     CDS             30263..31354
                     /gene="phnW"
                     /locus_tag="IVD26_000308"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAP6078314.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            31347..31475
                     /locus_tag="IVD26_000309"
     CDS             31347..31475
                     /locus_tag="IVD26_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAP6078315.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            31479..32024
                     /locus_tag="IVD26_000310"
     CDS             31479..32024
                     /locus_tag="IVD26_000310"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAP6078316.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(32478..34169)
                     /locus_tag="IVD26_000311"
     CDS             complement(32478..34169)
                     /locus_tag="IVD26_000311"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAP6078317.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(34589..35536)
                     /gene="arcC"
                     /locus_tag="IVD26_000312"
     CDS             complement(34589..35536)
                     /gene="arcC"
                     /locus_tag="IVD26_000312"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAP6078318.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(35651..36670)
                     /gene="argF"
                     /locus_tag="IVD26_000313"
     CDS             complement(35651..36670)
                     /gene="argF"
                     /locus_tag="IVD26_000313"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAP6078319.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(36761..37990)
                     /gene="arcA"
                     /locus_tag="IVD26_000314"
     CDS             complement(36761..37990)
                     /gene="arcA"
                     /locus_tag="IVD26_000314"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAP6078320.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            38451..39152
                     /locus_tag="IVD26_000315"
     CDS             38451..39152
                     /locus_tag="IVD26_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP6078321.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(39761..40777)
                     /gene="tsaD"
                     /locus_tag="IVD26_000316"
     CDS             complement(39761..40777)
                     /gene="tsaD"
                     /locus_tag="IVD26_000316"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAP6078322.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(40774..41238)
                     /gene="rimI"
                     /locus_tag="IVD26_000317"
     CDS             complement(40774..41238)
                     /gene="rimI"
                     /locus_tag="IVD26_000317"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP6078323.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(41245..41787)
                     /gene="rimI"
                     /locus_tag="IVD26_000318"
     CDS             complement(41245..41787)
                     /gene="rimI"
                     /locus_tag="IVD26_000318"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP6078324.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(41771..42595)
                     /gene="tsaB"
                     /locus_tag="IVD26_000319"
     CDS             complement(41771..42595)
                     /gene="tsaB"
                     /locus_tag="IVD26_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAP6078325.1"
                     /translation="MYYCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDNIIVPMFDARRKNVYAGAY
                     RWKENRLETVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFSEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            complement(42684..43664)
                     /locus_tag="IVD26_000320"
     CDS             complement(42684..43664)
                     /locus_tag="IVD26_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP6078326.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(43688..45172)
                     /gene="galT"
                     /locus_tag="IVD26_000321"
     CDS             complement(43688..45172)
                     /gene="galT"
                     /locus_tag="IVD26_000321"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAP6078327.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(45184..46173)
                     /gene="galE"
                     /locus_tag="IVD26_000322"
     CDS             complement(45184..46173)
                     /gene="galE"
                     /locus_tag="IVD26_000322"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAP6078328.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            46421..46588
                     /locus_tag="IVD26_000323"
     CDS             46421..46588
                     /locus_tag="IVD26_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAP6078329.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(46650..48461)
                     /locus_tag="IVD26_000324"
     CDS             complement(46650..48461)
                     /locus_tag="IVD26_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAP6078330.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(48458..48823)
                     /locus_tag="IVD26_000325"
     CDS             complement(48458..48823)
                     /locus_tag="IVD26_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAP6078331.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(48986..49381)
                     /locus_tag="IVD26_000326"
     CDS             complement(48986..49381)
                     /locus_tag="IVD26_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP6078332.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(49399..50361)
                     /locus_tag="IVD26_000327"
     CDS             complement(49399..50361)
                     /locus_tag="IVD26_000327"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAP6078333.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(50361..50573)
                     /locus_tag="IVD26_000328"
     CDS             complement(50361..50573)
                     /locus_tag="IVD26_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAP6078334.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(50594..51292)
                     /locus_tag="IVD26_000329"
     CDS             complement(50594..51292)
                     /locus_tag="IVD26_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAP6078335.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(51312..51854)
                     /locus_tag="IVD26_000330"
     CDS             complement(51312..51854)
                     /locus_tag="IVD26_000330"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAP6078336.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(51986..52990)
                     /locus_tag="IVD26_000331"
     CDS             complement(51986..52990)
                     /locus_tag="IVD26_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAP6078337.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(52987..53976)
                     /locus_tag="IVD26_000332"
     CDS             complement(52987..53976)
                     /locus_tag="IVD26_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAP6078338.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(53973..54779)
                     /locus_tag="IVD26_000333"
     CDS             complement(53973..54779)
                     /locus_tag="IVD26_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6078339.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            54945..55901
                     /locus_tag="IVD26_000334"
     CDS             54945..55901
                     /locus_tag="IVD26_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6078340.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(55978..56496)
                     /locus_tag="IVD26_000335"
     CDS             complement(55978..56496)
                     /locus_tag="IVD26_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP6078341.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(56584..56733)
                     /gene="rpmG"
                     /locus_tag="IVD26_000336"
     CDS             complement(56584..56733)
                     /gene="rpmG"
                     /locus_tag="IVD26_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP6078342.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            56961..57407
                     /locus_tag="IVD26_000337"
     CDS             56961..57407
                     /locus_tag="IVD26_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAP6078343.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(57602..59497)
                     /gene="asnB"
                     /locus_tag="IVD26_000338"
     CDS             complement(57602..59497)
                     /gene="asnB"
                     /locus_tag="IVD26_000338"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAP6078344.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT        16922 a        12696 c        10384 g        19769 t
ORIGIN      
        1 tattttatat gaaaaagtta ggttttattt tattgttggt ctctttattc cttgtaggat
       61 gtacgtctcc tagtaaagaa aatagtgatc catctgcgac cacagacaaa agttcaatca
      121 gacaaaccag ttcagctgaa aaatcaagta ctcagaaatc agcttctact gaaacgaata
      181 catcttcaac aagcagtaaa gtctcagagc ccaatacttc ttctacatct agtagtacag
      241 ttgagacaaa tatttcttct tcaacaatag acacaacctc ctcacagtct tctcagtcaa
      301 tagatccgtt agcaggatat tctgatctac aaattgagta cgcacgtgtt tggctagcta
      361 ttagaggtaa tacttttaga gatacatcgg gtgatttcga attacatgtt attcattatc
      421 ctgcaggaac acctatcgcc ccttatgatg cagggagtgc agtctatccg aaagatgtgg
      481 ttatgctcac tgggaaatac agttaccagg gagttttagt gtattcaagt aaccatgacg
      541 ggacaatcac tagttatcca gttccttcac attggcaaat gcctgcagat caaacatctt
      601 atccagcgtt cattagagaa acaactcaag aaatcattga taatgcatct gtagtagcta
      661 ttcctacagg aaatcccaat gacgtgaaac agttaatcga tgtgacagtt atagataatt
      721 agactttcta atatgttata caaaaagaag ctgacagcat tttgtcagct tctttcactt
      781 tcttttctat ttagatttat tggtctttga tagactccaa ggcaggaaaa aattttttaa
      841 ataaacgttt gcaaaacagt cgcttttcta tcttctaccg ctacttctgc ataggcacca
      901 ttaatcaatg tcagttgtgg cggtacatga ccacaatcaa tatcatacaa gatcggtagt
      961 tttaattcct ttgacagatc ttcgtataca tccttcattt tataatctaa caaatcctct
     1021 gccgcacttc taccgaacat gatccccgag ctgccatcaa accagcctgc cagtttcatc
     1081 tgaacaagtg atcttcttaa atcaactgac gatagctcac agttttctag aaaccacaag
     1141 atcggctttc catcattata ctttctttta aaagattgga catctccata aggagtaccg
     1201 attaaatgcc tgatcgtatc aatacaacca cctaataatc gtcccttcat ccttactgca
     1261 tctccgctga ctgattgcca atttgttggt tcagtgagat ggaaaacaga agatgatgaa
     1321 tgctcatggg gccacacttt ttgatacttt tcagaagatt gctgtagaat cgattctcct
     1381 tctcttgttt tcagtacact ttcccacatt gctgtcgttt catccaagta ctctcctctt
     1441 aaatcaataa ggttagttcc atgtgcagtg gctatccctg tttttaatgt gacagcaagt
     1501 agcaacgtac taatatctga ataacctact atccattttg gttgtagagc atcaaaatcg
     1561 acaaaatcga gaatctcaat caataattct cctccccaag tcggaaagat catttggata
     1621 ttttcatctt gcatcatttg attgaattca tctgctcgtt ttcttgctgg acctgatttt
     1681 tccttatctt gcgtccaaag cgtctttcca gtaactactt ggaaagattt ttcttccatt
     1741 ctctttaaag ctgattcgag taacgaatgg tgttcctctg atacgcctga ggatggtgca
     1801 gtaaccccaa tcgttgcatt tctttctaat aatggataac ttatcatgtt gcttcacctc
     1861 caagtatgca ctattttact tggttaattg tttttttcgt ttgccggcat caaaaatatc
     1921 ggcatctcaa gtagctggat gattttgttt aagtcaaccg tttggatgac catcgtttga
     1981 tctggtctac ctggtgcaaa aacaagtttt tcatttgata agagctcttc atcaataata
     2041 atcggaatct gtttttcata accaaacgga gaaacagcgc cctgcttttg tcccgtttgt
     2101 tcttccatgc gttctgatga aacaatagaa agccttttac cgacgatctt ccctaatgct
     2161 ttgaaatccg tttgtttcgt agtaaaagtc agatatacgt agttattatc ttttttatct
     2221 tttaagaata agcttttggt ctctgtacct gtaaatcctt gttctttctt tattaccaaa
     2281 gcatcttcat ttgtataaat ggctcgatga tgatacaact caaaatatat attttcgtgt
     2341 aagaatttct ttgccaagtc aatcattttt atgtctcttt tctattttat tatttgagac
     2401 atcttatcat ataaatatag cggttacaac attacttgtg ttttgttcgt tttttataca
     2461 taactattgt ttttctggta aaataaatca aaccacttaa tggaggcgtt ttagaatgga
     2521 aaaatttcag ccgatcatca atcaaatcaa agaaaaagaa catcaacaaa agatcaaaga
     2581 cctttttgct aagataacag aaacgtatcc ccagctagac acaactgtaa aatggaacca
     2641 acctatgttt actgaccatg gtacctttat tattgcattt agttttgcta aaaatcattt
     2701 ttctatcgca ccggaaaaag cagcgattcg tgcccttgaa aaaaatatcc aagaagcagg
     2761 ctacgtatat acggataacg tcatcaaagt tccttggaaa agtgtaatca actgggaatt
     2821 gattgaacaa ttgatttcat ttaatattga agataaaaaa ggtcatgata aattttggcg
     2881 ataaagcttt atacgaataa accttttact ggcgaggaaa ctattcatca ccttatacag
     2941 gttttgttca atcctatcct ttttatcatc cctggttaaa cacttaattg acaaagtatc
     3001 tgctattttt ataaggagtc tttcttgtgc tgaaaaaaat cactgattga atggctttga
     3061 attttctact tagtaaaatt attttttcag caattttcct gcaaaacttt tgaataagga
     3121 aaaaatacga gaaaatatca gtgatctttc ataatactgc ccattatttt caggtatatt
     3181 taaatataat atcactttag gagagaacga atttctttag agaaataaaa gttagaattt
     3241 tctgacttga tttttacaat gaccttaatt aaaatcgttc tttctacatt tcgtgattaa
     3301 gcaaatatca actaagtcag tagaaccatt cacataggag ggtgaacatt gaaagatttt
     3361 tactcagtaa atgaattagc cgaacaatta ggtgttacta cacgttctat cagaaattat
     3421 cttcatgaag gaaaactaaa aggaacaaag gttggcgggc aatggaaatt ttctgaacgt
     3481 aatctttttg agttcctata cggagatcaa gcagaggaag cagcaaaaga aatgcagcga
     3541 ttcatgctaa atgcaccaat cacgatgcgt ttcaaccttc aatatcgtga ttttacagca
     3601 atcaatcaat tccgagaaca attagtccag taccataacg atgtttacgc aaataaaaaa
     3661 gaccgtcttt tacaatacga tctttataaa gacaatcatg cggagatact aatcggtggt
     3721 aacttcaatt atgtcgtaaa ctttagtcaa tggatcaatg aaaaattatt gatccagaca
     3781 gatatttccc ttgtatctta aacaattaaa aagcgctaga aattccagag atgttggaaa
     3841 ttctagcgct atttttttat aagtacttac tgtttggttc aaacaaatat ttttttaata
     3901 aatgaaattt taccatcttt atcctcaaat ctttatcctc aaataaagac cgtgaccatg
     3961 cttcctacta cgatcagcaa taatccgata atcgttaatt ttttttcttt tggtgtctta
     4021 ttttcatgca ggatgtacat accgcctaat gtagagataa ctacgtttag ctgtgtaatg
     4081 atatatgcag tagcaacccc attttcattt gctgaaaaaa tataagccaa tgctgacaca
     4141 ctaaagatgg ctccaacgat cgttgctttc caactcttgt cttcagaaaa tgcggttggt
     4201 ttacggaaaa tcacataaat cactgcccct aaaaagacac cgatcatttg cggaaagaaa
     4261 atggaaagtc cgcttgcatc aactagttta ggcaatgcac tgtataccca ataaccaata
     4321 cttgttgatg ctaatagact aattcctttt gtgataccgc ctttttttcc aggatcatca
     4381 ctgattgccg ttaaagcaga accaaataca agaagaatga ttgctgctgc tccaatgatt
     4441 ttccccatac ttccagacca ttctccaaaa gcgaagacac caatcaacga ggttccgact
     4501 aactgtaatg cagtcgaaat tggcatcgtt ttagaaacac caatcaagtt gaaagatgta
     4561 tactgtcctg tttgtccaat aacccaaaat gcaccagaaa gtaaactaat caaaaatgta
     4621 gtcactgaaa taccagctgg agaagcgaat aattgaacga gtaagccgac aagcaccgct
     4681 ccaataccag ttcctaatat ctcatttgtt ggtctgccac caatcttttt caaaatcagt
     4741 ggctggatcc cccagccaac tgccgggatc aatgcaatca ataaacccat ttttattcac
     4801 ccttatcctt ttccaccttg gaaagaagga tataaagtca tcccaccatc tgcaaatagt
     4861 gtaatacctg taacataact ggattcgtct gaagccaacc atgcagctgt cgccgctatt
     4921 tcttttggtt cacctacgcg tcctagtggg atcatacttt ccaagagttc tttttgttca
     4981 ggatcatcaa attttgccgc attaataggt gtacggatag caccagggcc tatactattg
     5041 attctgattc ccttcggtgc atactccatt gctaccgttt cggtaaataa ttttaccccg
     5101 ccttttgaag cagcgtaatg agcaaacgtt ggccatggga tctgttcatg aacagaagac
     5161 atattgatga tatttccttt tttattattc tctgtaaagt aatttaaagc cgctttcgtt
     5221 ccgataaaaa cgccagtcaa attgactttt aacactcttt cccaatcttc aaggctaagt
     5281 tcatgggttg gatgctgatt ttccatccca gcattattaa cccaaacgtc cagtgtccca
     5341 aaattttcta aagccgtatc aagtaaacgc tgtattcctt cttcagaact gacatctgct
     5401 tgtacagaga ctgcttttcc gcctgcctct tcgattgctt tgactgcttt ttctgctcct
     5461 tctttatccg agttatagtt gacaactaca ttcatttttt ctttcccgaa tcgttgagca
     5521 atcgctgttc caatcccctt tgagccacca gttactactg cgactttgtt ttctaattcc
     5581 ttgtacatag tacccactcc tttttcatac ctaaacctgt tattacggat aacttttatt
     5641 tccgccttaa agtgagtgta caccaagata tatagtctaa agcaaatgat acgctctagc
     5701 aatcgttttc atgaattgct agtgtccttt tatttctata aagaaagagg ttgtgacaga
     5761 agtggtcagc ttcaagaaat ttcggcttat ttccgaagaa gctacttctg aaaaaccatt
     5821 tatttggaaa aaaaggctgt gacaagactt ttgtcacagc ccctttcctg ggcttattta
     5881 tcacccattt tattgtaatt gctagttata cataaacaag agattttatg cataatgttt
     5941 tattgctgag aaaaatattc agctgttgct tgttcatcct ccttgagttg ttcaatcaat
     6001 tcctctacac tagaaaattt cacttgatct cttaaaaatt gattccagcg taccgcgaca
     6061 tgttcaccat agatatcttg attaaagtcc aaaatataca actctacagt cagctcccgt
     6121 ccttcaccga atgtatcatt atgtccaatt gaacccatgg ctggatacca tgtttcccca
     6181 atttttattt ccgacacata aacaccttct ttaggcaaat gaaccgtgct ctttactttg
     6241 acatttgctg tagggaatcc tagtagtctg cctcgtgcat cgccatggac aactacccct
     6301 tctacctcat atgtgcaacc taatagtttt gctgcttctt ttacttgtcc gctgtctagt
     6361 aatccacgaa tacgggtaga gctgattttt tcaccttgtt cttcttcttt agaaactgtg
     6421 acgattttga atcttccttt ggcatattca ggaaaatgag cgacatctgc aatgtctttt
     6481 ggtccatacg tataatcaaa accggaaaca gcatattttg catgtaaccc tacgatgtat
     6541 tgatcaacaa attcctgcgg tgctaaatga gcaaaagaag aagtaaaatc aacttcatat
     6601 aaataatcta tacccaaagc ggccattttt tcttcttttt gcttaaggct agtcaaatat
     6661 ttcacgctgc taggatcgat ctttttaaag acaatagatg gatgctgatt gaaagtcatc
     6721 aatgctaatt tcaatccttc tttttgtgca atttccatac ctgtctttat gactttctgg
     6781 tgtccgatat gcacgccgtc gaaaaatccc agcactaaaa cgacatcgtc ttctggaatt
     6841 tgttctgatt ggtaaggatg tctgatcttg atgatattca ttcgttattc ctcatttctc
     6901 aatactttac taggttttaa tttgtttttt tctttcgggt ttggctgata aatactgaca
     6961 acttttcctt tataaaacaa agcaatttct tctgacggca tttctgggag cgcaaataca
     7021 gtataatcaa gtctcatacc gttttttact ttctgccata cttcatcagt aatatctact
     7081 cgtttgaacc gttccactcc tttttctatt ggcagcaaac aatcatcgat tgtcccattt
     7141 ttcacagctt gagctacttc ttctaatgtc agagcatcct tctgggacat accggcactt
     7201 gctgttcggg tcagatcaga catgtgcgca gggtaaccaa gtttcttgcc tgtatctaca
     7261 gctaatgtgc ggacataggt tcctttcccg cattctactt cgaagcgcca agaaatggtt
     7321 cctgtcactt cgtctcttgt caattcactt gtccggataa aacggtaaat ctgagccttt
     7381 ctaacaggac gctccactgt ttcattattg cgggcatatt catataaccg cttaccgttg
     7441 acttttaccg ctgagtacat tggtggtatc tgggtgatct caccaataaa tgaagccatc
     7501 acttcatcta tttttttttc agataaagac atatctactg gttttgtttc tacccgttct
     7561 ccggatcgat cttccgtcgt tgtactgaaa cctagagtta tctcgcctac atagattttc
     7621 ccagaatctg tcaaatattc gataactttt gtggcttttc caatacaaat gggcaacaca
     7681 ccgtctacgt ctgggtcaag cgtaccccca tgtccgattt ttttcgtatg taagattttt
     7741 cttaatttga atacgcaatc atgacttgtc attccgcgtt ctttccataa aggtaataac
     7801 ccgtccatgt cttttctcca tttcattttt gatttaactg aattattata acacattgca
     7861 tcaattactg acgaatttga catcataatg aacggttttt atttttcggc aataaaaacg
     7921 taacaaaatt catgctcacg taaatagaaa tcatgttatg cttttttaaa ggagggaata
     7981 gaatggaaga ttttttcttt gcaccatttg attggattta tgggtggctt acaggtaaat
     8041 agtttggttt tcacttccca aaaacgaaaa aaaagactgg ccattcttcc agtctttttt
     8101 ccgttttttt tatttatttt ttcagtttct taatcaatgt aaaaaattct attttgcggg
     8161 atcgatttta tcattttatt ggtcaagatt tttccatttc caatccaata cttctggcag
     8221 atcaatacca ttttcacgaa tatagttttg atgttcttgt aatttctgat ccattttttt
     8281 cgcaaaatct tctgcttgac ttcctttgat ttttaaagct gcgtcttttg ccaaatgata
     8341 acgatcaagt tcatttacta cacgcatgtc aaatggtgtc gtgatatctc cattttcttt
     8401 gtagccatga atcattaaat gatggttatg acgatcaaag aaaatcgtgc ggaccaatgt
     8461 ttcataaccg tggaaagcaa ataagatcgg tttgtctttt gtaaaatatt gatcaaattc
     8521 ttcatcgctc aacccacgcg gatcttgact tggatgacgt aatttcaata aatctacgac
     8581 attgatgaac cgaattttta gttttgggaa ttcttccagc agcaaagtta cagctgctaa
     8641 tgcttctaag ttagattccg ttcctgcagc agcaatgacc aattcaggtt cctcctcttt
     8701 tgctgtcgaa gcccaatcaa tgattttcaa gccttcattc actaagacgg ctgcttcttc
     8761 tgctgagtaa aattgagcac gcggatgttt ggaagagatg atcaaattga ttttttctga
     8821 cgagcggaat gctttatcca tgactgcgag caatgtattt gcatccgcag gcagatattc
     8881 acggatgaac tccgccttct tttctgccaa atgtgtcaat attcctggat cttggtggct
     8941 atatccattg tgatcttgct ggaagactgt tgagcttgca atgagattta gcgaaggata
     9001 atcatttcgc caagaaaggt catgtgattt ccgcatccat ttgaagtgct gagtcaacat
     9061 agagtcaacc actcgcaaga atgattcgta acttgcaaaa aaccatgccg tccagtcaga
     9121 acgtaccctt ctaagaaccc ttcatcttgg tgttccgata attgactgtc gatgacgcga
     9181 ccagatggcg aaagccattc atcattttct ggttcgattt tttccatcca ttggcgattt
     9241 gtcgttttga aaacttgatt caatcggttt gattttgttt catctggtcc aaatatacgg
     9301 aaattttctg gatttttctc aatgatctcg cgaacgaatt taccaagttc ggtcatatct
     9361 tctgctttaa cggagcctgg tttttcaaat tgcaaagtat attttttcca atctggcata
     9421 ataagcggtc ttggatcgat tccaccattg gtgataggat tttttgccat tctttggtca
     9481 ccagtaggcg cgatttctct gatttcttct aaaatacgtc cttgtgcatc aaataatttt
     9541 tctggttcat aggatttcag ccaacggagt aaagcatctg catgatccat atgttcttga
     9601 tctacaggaa tcggtacttg gtgtgctcgg aaggttcctt caattggttc cccgtcccat
     9661 tcttttggac cggtccatcc ttttggtgtg cgtacgatca atactggcca ttttggcatc
     9721 acgacatctg ttgctgtctt caggcgagct tctttttgga tggatttaat tttctcgatt
     9781 gcttgatcca ttttttcagc cataacagga tttaattttt ctgaatcatt tccttcaata
     9841 aagaaaggtt cccagccaag tccgttaaag taatttgcta attctccatc tgatttacgt
     9901 gccaagatcg ttgggttggc tatttttgca ccatttaaat gaaggatcgg taaaacagct
     9961 ccatctatca ctggattgat aaagacattt gagaaccagc ttccagctaa aggaccggtt
    10021 tctgcttcac catcaccaat cacgacagca gagattactt caggattgtc taatacagct
    10081 ccgactgcat gtgaaagaga gtatccaagc tctccgcctt catggataga acctggtgtt
    10141 tctggtgctg catgagaagc aatgcctcca ggaaatgaaa atcgtttgaa taatttttgc
    10201 attcctgtct catcttccgt tacttctgga tagatctctg tgtaacttcc atctaaataa
    10261 gcattcgata ccatgacttg tccgccgtgt cctggccctt caatataaaa catgttcaaa
    10321 tcatatttat tgatgactcg gttcaaatgg acataaataa aattttggcc aggaatcgtt
    10381 ccccaatgac cgattggatg ttttttgaca tcttcgggtt tcagtgtacg tctcagtaag
    10441 gggttatctt taagataaag ttgcccaaca gaaagataat tagcagcacg ccaccaagcc
    10501 gtcattttat caaagtattc tttactagaa taatccatac ataacactcc ttttcattat
    10561 tactcttatt ctagcgcaga tactcccaat tgaaacctaa taagcacttc tgttcatttg
    10621 tttggatttt atatctagcc aaatgaacag gtataaaaaa ccacgaaatt tttcctttcg
    10681 ctgacgtttt ttacattgat ccaaaaaact tgtcgttatc acaatggctg ttccgcagtt
    10741 catttcgctc ctcatcatgc ataatttgct gaatgacgct gggccagtta acacattgct
    10801 ggaaaactgg ggctggatcg agcaattcct ttcctgattg atccgtttta tgtaaaagtc
    10861 tctgttatct ttgtcaatat gtgaattggt atcccagcta ctatgctaat ttctacaggg
    10921 attatccaaa atttggatcg tgaccaaatc gaagcggcgt aatcggaaat atcaataact
    10981 tcaacgtgat ttttctttta actgtcaacg gaccgacaaa ctcaaacttt tatggtgcag
    11041 gttccactga tcttctagtt acttggctat acctgactgt cactaaaata gattacaatc
    11101 tagcttccgt tatcggtatc ttgatcttta tctatatgca aaaatttata tactactaga
    11161 aaaaagaaag tcgaattttt tacttttctt tttctctttt ttggttagct gacacgccgc
    11221 aagactaaag tcatggaact cttaggtaat acgtcttaat gaaaacaaaa aaatcccgca
    11281 acccctgatt tcacaggatt tgcgggagtt tttgattagt ctttgttcaa gtcgcgaagc
    11341 aattcatcga tatggttgcc atagacaact gattcatcaa gttcaaagaa caattcaggt
    11401 gtcttataaa tacttagatt gtgccctaac tctcgacgaa tcaatcctga tgctttattc
    11461 aatccatctt gtgctgtttt cttatctgat gctaagtcag ataaaatgct gtaatagatc
    11521 gttgcttgct gtaagtcccc cgtaactttc acatctgtga tcgttacgtt ctccacacga
    11581 gggtcacgga cctttttgcg caaaatatca ttgacttctt ttaagatttc ttgaccgact
    11641 cggcggtcac ggtagttagc cataatgatt ggcctccttt tatcagtttt tagtcatttt
    11701 tgacttcttc catgataaat ccttcaatta cgtcatctac tttgatgtca ttgaattttt
    11761 caatcattgc accacattca taacccattt tgacttcttt cacgtcatct ttgaatcgtt
    11821 tcagacttgc aagttggcct tcatagatta cgattccgtc acggattaca cggacaccgc
    11881 tatctctacg aatatatcct tctgttacat aggcacctgc aatcgtacca actttagaaa
    11941 ctttgaaggt ttcacgaacg atcatttgac cggtgatttt ttcttcaaat tcagggtcta
    12001 gcatcccttt catcgcagtt tcgatttctt cgatggcttt atagatgata cggtgaagac
    12061 gaatatcgac ttcttcagta tcagcttgca cttttgcctg cggtgtagga cgaacgttga
    12121 aaccgatgat aatagcgttg ctggctgctg ctaaggttac atcactttca ttgattgctc
    12181 cgacagctga atggacgatt tttacacgga caccttccac atcaatcttc ttcaatgatg
    12241 cagccagtgc ttctgctgaa ccttgtacat ctgctttgat gattacgtta acttctttca
    12301 attcgccttc tttcaggctt tcaaataagt tatccaaagt cacacggctt gtggcagcac
    12361 ggttttctaa taatgcacgt ttcgcgcgtt cttcacccgc tgcacgtgct gtcttttcgt
    12421 cttcgaagac tacgaaacgg tcacctgctt gaggtacatc attcaagcca gtgatttcta
    12481 ctggcgttgc aggtcctgct tctttatcgc gacggccaag atcgtttgtc attacacgga
    12541 cacgtccgta agtattaccg acaacgattg ggtcaccaac atgaagtgtt ccttcttgga
    12601 caagtaaggt tgacacagga cctttacctt tatcaagacg tgcttcgatc actgttccga
    12661 ttgcgcgttg tgttggatct gcttttaaat cttctacttc tgcgactaac aggatcattt
    12721 ccagcaattc ttcgatgttt tggccgaatt tcgctgagat ctcaacaaag atcgtttctc
    12781 caccccatgc ttcaggaatt aactcatact cacttaattc ttgcataaca tgttgagggt
    12841 ttgcacctgg tttatcaatt ttatttacag cgacgatgat tggaacgcct gcagctttgg
    12901 catggttgat tgcttcaact gtttgtggca tgacgccatc atctgcagca acaactaaga
    12961 tcgtgatatc tgtgatactt gctccacgtg cacgcatact tgtaaaggcc gcatgtcctg
    13021 gtgtatccaa gaaagtgatt ggtttaccat caatatcgat ctggtaggca ccgatatgct
    13081 gtgtgattcc gccggcttcg ccgcttgtta cacgtgaatg gcgtaatgta tccaataaag
    13141 ttgttttccc atggtctacg tgtcccataa tcgttacgac tggcggacgt gagactaatt
    13201 tatctggatc gacttcttct gcctcgaaga atttatcgat atcagcaatg tcaacttgga
    13261 ctttttcttg tggttccatg ccatagtccg tcgctaacag ttcaatcgta tctttatcca
    13321 gtgcttggtt ttgattgacc atgacaccaa gcataaataa ttttttaatg atttctgctg
    13381 gctcacgatg aatttttttc gcaatatctg ctacgttcat accttcagta tactctaata
    13441 catctggcaa ttcacggaat ttgcgtggtg gtacagctgg tttagttgat tgttgctgtt
    13501 tgcctttttt acctttttta ttataacgat tacggttatt attattaaat ttgccgcgat
    13561 tgttattgtt tggtttgttg ttattgttag tacggttttg attgccgcct tggctcgttc
    13621 cttgacgatt ttggctgctg gtatttcccg tattattttg gtttgttgtt ggtttttttc
    13681 cttgattcac ttgaccgctc ccttgaccgc gatcttgata actgcggtta tttttatttt
    13741 tttgttgatt gttcgttgtt tcttttttac gttgatcgtt cggctgttga ttggctggtt
    13801 ttctgcttgc ttgttgtgca gcttgttgtt tcgtgcttgg gtttttgaac gcttgttgca
    13861 atttcttctc atcattgcta gtaatcgcac ccatatggtt tttcacatcg atgccaagtt
    13921 gttgtgcttt ttccacgacg tctttactag attttttgag ttcttttgct aattcataga
    13981 ttcttttgtt gcccatgcaa tcaccttcct aaccttcaat tagctccttg gtcttcttcg
    14041 caaatccggc atccattatt ccgaatacct tgcgaggttt tccgatcatc tgcgtgattt
    14101 ctgcttcaga aaatagctca aagcaaggaa cttcataata tgaactctta tcttttatct
    14161 tttttcttgt attctcgctt gcatcggttg ccacaaacac caattttgct ttttgtttgc
    14221 ggatttcagc aatggtcagt tcttcacccg tgattagttt tcccgcgcgc atcgctagac
    14281 cgatgagatt catggctttt tgccgattaa ctgtattcat tttccaaata actctttacg
    14341 tgctttttgg tgagtgacat agtcaagaag ttcttgataa aactcatctg ttaatgttgt
    14401 ttcgagtact cgatcgagaa tttttttatc ccaagcttgt tgtacttctt ccggctcaag
    14461 tgagacatac gctcctcgtc caggcatttt tccagttgga tcgatcgata cttccccttc
    14521 ttttgaacgg gtgattcgga ccatctcttt tttaggtttc atttcacctg aaaccacgga
    14581 tttgcgtaaa ggaattttcc tttgtttcat ctctttgcct ccttactaaa gttaagcttc
    14641 tggtttttct tcgaccgttt cattgttgaa tgcaattgtt tcatattcat cgtctgttaa
    14701 atctgactga acgattgctt catcatgcag ttcttctgtt tctttttgtt gttcttgatt
    14761 ttcataaaat tccgtcatgt cagattctga tttgatatcg attttatggt tagtcaattt
    14821 agcagctaaa cgtgcgtttt gtccgcgttt accgattgct agcgataatt ggtagtctgg
    14881 aacgacaact gtgcaggcct ttggatttgt ctcatcgaag atcacatcca tgacttgtgc
    14941 aggattcaat gcatttgcaa tgaatacagc tggatcttca ttccattcga cgatatccat
    15001 gttttcgcct tttaattcat tgacgattgc ttgaactcgt tgtccctttg gcccgacaca
    15061 tgtaccgact gcatcgatat ttggatcatt tgagcgaact gccacttttg aacgatcgcc
    15121 agcttcacgg gcgatgctga caatttcaac gattccatca tagacttctg gtacttcttg
    15181 ctcaaataag cggcgcaata ggtctggatg gctgcggcta acaaatactt gcggaccttt
    15241 agacgtattt tctactcggg aaacataaac tttgattcga tcatgtggtt gataaaattc
    15301 atttggcatt tgatcttgtt tagaaagaac tgcctcaatt ttaccaagat tgacataaat
    15361 ataacgttta tcctggcgtt cgacgattcc ttgcatgatg tctttttcat aagcactgaa
    15421 ttcgttataa ataatcgttc tttctgcttc acgtacacgc tgtaaaataa cttgtttagc
    15481 cgtttgcgca gcgatccgcc caaaatcttt tggtgttact tcaaaacgga tcgtatcacc
    15541 gatctcatat gctggattga ttaaaagtgc atctttcaat gagacttcca actgtgaatc
    15601 catcacttct tccgttactt cttttaccgc atagacatgg atctttcctt ttttctgatc
    15661 aaattccact tcgacgtttt gtgcttggcc atagtgacgt ttgtatgcag aaaccaatgc
    15721 tgcttctaaa gcatcgatca cgatttcttt tgagatccct ttttcagctt ctaaagcgtc
    15781 taacgcattt aacatttctt tactcatttt ttctgattcc tctccgtgat taaaattgga
    15841 tagctaagcg agcttttgca atattttttc ggtcaaaagt caattctttt tctcgtgttt
    15901 ttatgcgtat tttcaatgta agctgttcag catcaaatga ttgaagaaat ccttcatatt
    15961 gtttttcgcc atctactggt tggtataagg agacatggac ataatcacca agtgcctttt
    16021 catagtcgct ttcttttttc aatggccgct ctgctcccgg ggaggatacc tccaggaaat
    16081 aagcttgagg aatcggatct ggatctgctg catcaagttt ttcactcagt ttctcactga
    16141 caaaggcgca ttcttcgata tcgataccgc cttctttgtc aataaatact cgtaagaacc
    16201 agctttttcc ttcttttaca aattcgactt cgacaagttc aaaattttgt tcatctaaaa
    16261 tcggtgtcac catttctgtg actgtttcaa cgacgctact caaaagtttc gcctccttaa
    16321 aaaattaagt gcgtaattcc attaaaaaga gtgagcgaaa aatccgctca ctcacagtta
    16381 gtatcattac ctataagaac tataccatac tctgcttaaa attacaagca gacaggaaaa
    16441 cagatgctta tagcatatcg aataacgata attgattttc atctggtaga tctttcaata
    16501 cgccattgtc gttcatatat tcgatcaatg tttttgaaac tttaccgcgg gtggcaagat
    16561 cttctttgga taaaaatgga ccgtcttttc ttgcttcaac gatttgtttt gccacgttgg
    16621 ttcccaaact tgggacagct ctaaatggtg cgatcaacgt atcaccttca ataacaaagt
    16681 taacggcatc cgatttatac aaatcaatca ttccaaattt gaatcctcgt tccagcattt
    16741 cattggctaa ctccagcact gtcagttgat tcttttcttt tacggaagca tctaatcctt
    16801 tgtccgtgat ttctttcatt gcttgtttca cagcatcttt tcctttgcac atggagacta
    16861 gatcaaagtc gtctgcacgt acagaaaagt atgcacagta atacaaaata gggaaataaa
    16921 ccttgaaata agcgacacga agagccatca atacgtaagc tgcagcatgg gctttcggaa
    16981 acatatattt gatttttgaa caagaatcga tataccagtc gggcacatta ttttctttca
    17041 tcgccgatag ataggtttct cgcaattcat cagggatctt gttccattgt cctttacgaa
    17101 cagtttccat gattttaaat gccatcccgc tatctaatcc agcatggatc aaataaacca
    17161 taatatcatc acgacagccg attacttccg ccagtgtcgc atctcctcgt cgaatcaatt
    17221 cttccgcatt tcctaaccat acgtctgtac catgagatag tccggaaatt tgcagtagtt
    17281 ctgcaaaagt tgtaggatgc gtttcttcta gcatccctcg aacaaaacga gtgccgaatt
    17341 ctggaatacc taatgtccct gttttggaat aaatttgttc ctgacttact ccaagtactt
    17401 caggaccggc aaatatccgc atcacttccg ggtcatccgt agggatcgtt tgtggatcga
    17461 tccctgataa atcttgaagc atccgaataa cagttgggtc atcatgccct agaatatcta
    17521 atttcaatac attatcgtga atcgagtgaa aatcaaaatg agtcgttttc cattccgaat
    17581 tttgatcgtc tgctggatat tggatcggcg taaaatcata gacatccata taatcgggaa
    17641 taacgatgat cccccctgga tgctggccgg ttgtccgttt gactccagta gcgccttttg
    17701 ctaatctgtc gacttctgca cttcgaaact gcagattatt gtccctttcg tatcctttta
    17761 catagccata tgctgttttg tcggcgactg taccaatcgt tccggcacgg taaacatagt
    17821 cttcgccaaa caatactttc gtatagttat gggcttctgc ttgataatca cctgagaagt
    17881 tcaaatcaat atcgggcact ttgtctccat ggaatcctaa aaatgtctca aatggaatat
    17941 catgaccgtc tttgtttaag cgtgcaccac attttggaca ttgtttttct ggcatgtcaa
    18001 atccagaacc atacgtacca tcttcaaaaa actcggaata ttggcactct ggacaataat
    18061 aatgaggggc taacggatta acttcagtga ttcctgtcat cgtcgcaaca aagctagagc
    18121 caacagagcc acgtgaacct actagatagc catcttcatt acttttatgc actagttttt
    18181 gggcgatcag ataaataacc gagaagccat taccattaat agaattcaac tcttttttta
    18241 atcgtttttg aatgatctca ggtaacggat ctccgtacat ttgttttgct tttgtgtaac
    18301 tcaattctga tatttcatct tctgaacctg gaatcttcgg tgtataaagt tcatctttga
    18361 ctggaatcac ttcttcgcag atatctgcga ttttattcgt attttctact acgatctctt
    18421 tcgctgtttc ttcccctaaa aagtgaaatg cagttagcat ctcatcggtt gttcggaaat
    18481 ggacatccgg caaactatga cgattcaacg gattcgctcc gcccatagaa ttgatcaaaa
    18541 tttttcggta aatggcatct tcttcgttca gataatgtac attacctgtt gcaacaacga
    18601 ttttatccaa actttttccg atttctacca aattttggat aatttcttcc aaatcatgtt
    18661 cattttttac caattcttgc tcgatcaaag gcgcatagac cgcttttggc ataacttcaa
    18721 tataatcgta gaattttgct cggtttcttg cctcttctac ccctttttgc atcatggctt
    18781 cgaatatttc tcccttatca caagctgagc cgatcaatag attttcacgc atctttttca
    18841 attgggagcg tggtattcgt gggacgcgtt cgaagtattc gacattcgac attgaaatca
    18901 gtttgaacaa atctttcagt cctgcctgat tttttgctaa aatcgttaca tggaaaggtc
    18961 gagccctttt gtaagaatct ccttctccga tatgctcatt tagctgatca tgataaagca
    19021 tgttatgatt gtccattgcc tctttcacaa agatccatgc taagtgacca gttgcttcag
    19081 catcatagat tgctcggtga tgctgttcca agctgacacc aaatttttta gataacacac
    19141 ctaatccgaa acgtttgaat tgaggataca gatatctagc taattccaac gtatcaatga
    19201 ctggattggc cgcttcagga ataccatacc ttgcgtagct agtattcaag aaccccatat
    19261 caaaagccgc gttgtgggct accaaaattg tatcttttga aaattcaagg aacatccgca
    19321 atacttcttc ttccgacttt gatcctcgaa ccattccatc cgtgatacca gtcagatcta
    19381 ccgttgttcg tgacaaagga tgtcctggat cgataaattc atcaaagctt tcgatcacat
    19441 ttcctttata cattttgact gcggctagct cgatgatcgt gtcatatact gcagacaatc
    19501 ctgtcgtttc cacgtcaaat acgacatatg tggcttcact caatgcttca tgtgcatcat
    19561 tataagcaat tgggacacca tcatctacga cattcgcttc cacgccgtat aagattttca
    19621 cacctgcttt ttttccagca ctatgtgctt ccggaaaggc ttgcgcacca ccgtggtctg
    19681 taatggcgat agctcggtgt ccccatttcc ctgcttgtgc cacaagatca gagatgctgt
    19741 ttgttgcatc catcgtactc atattgctat gaacatgaag ctctactcgt ttttcccctt
    19801 caggagcata atctttgcga ggtgtatgtt tgacttctat gatatcttgc gcattcatga
    19861 ccaaatcacg gacaaacgta tcttcttgaa tacttcctcg tacctttaac cagctaccga
    19921 cactgatcgc atcaaatact tgttcatctt tttcgccgtt cgagaatttt ttgacgataa
    19981 atgatgaagt ataatctgtg attttcaaag tcaagatctt gcgttttgaa cgtagttctc
    20041 tgacttcttt gtcgaatacg tacccctcaa gtgtgactct tcgttcttct tcaacgatac
    20101 tgatcattgg tgtcgttggt tcatcggctg gaatatttcg tcctagctgg atgtggatgg
    20161 gtccttcaag agctggcgat tgctcttttc tttccttttt cttttgttcg tggacaacta
    20221 gactttcagc tgcttgcttc ataaaggctt ctgcctgttc ttgtttgcgt tcttcaaaaa
    20281 gtttcaatac tcgttccgct tgctgctcat ccacttctgg ttcgatacga aattttggga
    20341 atccgtaact gacgaacaac tcttctacta atggcaagta ttgttgcttc aaataagaaa
    20401 tagctcctgt actgtcgatt ggcaagatga ctttacgatc ttttatcaca ggtacctgcg
    20461 ttttcaatac ttgctgtgct agtggtgtat cgcattgctg attttccaaa gcttgggccc
    20521 agtaatcttg caagagctgt tcatcgaatg tctggtcatc tgctaagata ttcagtttga
    20581 cttgtgcaat atctttaaaa gcgatagtca gatgctgagt caatgaccga tatagcataa
    20641 taggcaaaat tttggaaaaa tgcagcgtaa attcccataa acgcgattta cgatggacca
    20701 ctacactatc catttcacca gcagtaagca gtggatgatt tttttctgct tcctctagtt
    20761 ggatttgttc caacagtttt tcaaataaat ctcgtttttc tgacaaagat atacgccctt
    20821 tctgatgaga aacaatgcaa ttgatcgcat cttatcctct tctttttcag taccttttag
    20881 tatactcgtt ttttctgagt tttacattaa aaaattggaa ctgcgattca aatcgcagtt
    20941 ccaattttaa aagcgaatca tcagattgtc aaaaacagct gattcagcta tttttatttt
    21001 ctgtgtttta acgcttatta ttcgccttgg ttcaagagga ttggtaaagt attcaccaat
    21061 tcttctttac gtacttcaac catttcgcca gttttcttga ttttcacttc tacgattcca
    21121 tccactgctt ttttaccgac agtgattctg attggacagc caatcaaatc agaatccgcg
    21181 aatttcactc ctgcgcgttc atttctgtca tcaaccagta cttcatagcc agcttttgtc
    21241 atcgcttctt ctagttcatt cgtcaggttt gtttggtatt cgtcttttag attcatttgg
    21301 acgatatgca aatcaaatgg cgcaattcct tttggccagt tgattccttg ttcatctgaa
    21361 tgttgttcta cgattgctga taataaacga cttacaccga taccataaca gcccataatc
    21421 acaaattttt ctcgtccatt ttcgtctagt acagttgctc ccatagattc actgtaacga
    21481 gtgccgattt tgaagatatg tccgatttcg attcctcgag taaaggcaag aacaccattg
    21541 ttgtctggtg aaggatctcc ttcttgtaca aaacgaagat cttcataaga aagtacagtg
    21601 aaatcgcgtt ctggattcac atttttatag tggaatcctg tttcgttcgc tccagtaatg
    21661 gcattcgcta aatcttggac ataacggtct gcatatactt ttacgtcatc tgaaacaccg
    21721 actggtccga cagaaccaaa ctcagcacct agatattttt gtgcttcttc ttctgttgct
    21781 tcttctaaaa agtcagcaga taaaaagttt ttcagtttta cgtcattgac ttcatggtct
    21841 ccgcgtacca aaacaaggac aggttgttca tccgcaatga acaatacaga cttgatgatt
    21901 ttttgaggtt caacagaaaa gaaatctgct acttcgtcaa ttgattttac gttaggtgta
    21961 gctactttct ccaattcaag ctgtgtttca tgcgattttt ttgatacata gtagcttgta
    22021 gccatctcca agtttgcagc ataatcactt tcagtcgaat aacagatcgt atcctccccg
    22081 atttctgaga tcgccatgaa ttcttttgag tctttcccgc ccattgcgcc accgtctccg
    22141 ataatcgagc gaaattctaa gccacaacgc ttgaatactt cggtgtaggc tttttcgtaa
    22201 tctttatatg tctcgtccaa actttcttcc gttgcatgga aagaatacgc atctttcatg
    22261 ataaactctc ttccgcgaag caaaccgaag cgaggtcgtt tttcgtcacg atatttaggt
    22321 tggatttgat aaagatttaa aggtaatttc ttatatgaat tgatttcatt acgcatcaaa
    22381 tcagtaaaag tttcttcgtg agttggtcca aggatcattt ttcgatcatt gcggtctttg
    22441 aaacgataca agtttggtcc atatgtttcg taacgcccgg attcttccca aagttctgct
    22501 ggcaagatgg caggcatcag catttctacc gctccgattt tttcaaattc ttcccgcata
    22561 atgcgtttca gtttttccaa tacacgattt gctaatggca gatatgaata aatacccgct
    22621 gatacttggc ggatatatcc agctcttagc aagatttgat ggcttaatac ttctgcatca
    22681 tttggaactt cgcgtaatgt tggaatcaac atttttgatt gtctcattct atatactcct
    22741 ttatttcctc aaaatagtta tcgtttgtta ttatacccta tttgtcaact ttttctagaa
    22801 aaagaatcgt tgaatatcgt tccatgtaac tagcaccatc aacaacatta aaaatccaaa
    22861 gccagctaat gtcaatattc cttctttttc ttgacttaat ggtttcccgc gaatcccttc
    22921 aaaaatattc aagactaatt tcccgccatc taaggcagga atcggaagca gattgacgat
    22981 tccgagattc attgaaagaa gcgccatcaa actaataaca gttgttacac cttgatttgc
    23041 tgcttctgaa gacaattggt acatcatgac aggtccgcct aatttatcta aactgaaacc
    23101 tgtaaatagt gatcctaagg ctttgaaaat ttccaatgaa ccgctgaaag cttgacgcgt
    23161 ccctccaatg atcttatcca taaaacctgt attcattggg gcttttatac caagttggcc
    23221 aactttttcg ccatttgact ctacagattt cggtgtcacg tcgacagatt gcacctgacc
    23281 ttctcgttcg atcttaaagt ctaatgtttt atccggattt ttcgtaatga ctgttgtcag
    23341 atcattccat gaatggattt cttttccgtc cacactgact acctcatcat tttcttttaa
    23401 gcctgcttct gccgcagctc cattaggcat gatctctcct acgcgattag tgttcgtcac
    23461 ttgaacacca ccttgcataa atgccagaat gatgaataac aggattgcca aaataaagtt
    23521 attcatgggt ccagcaaagt tggtcagcat acgctgccac aatttagccg attggaactg
    23581 tacgtctttt ggcgcaattc tgatttctgt tccgtcgttt tcaataatcg tcgcatcgtg
    23641 atcaacaggg taggttacta cttctgtttc gtctccattc acataaccag tgatagtcag
    23701 ctcatcttct aaatcataac ggctcaattc catcgggata gcatttgtca attggatttt
    23761 cttacttaaa tttatcttct ctacgatgcc gtcagaattt agtaaaagag aaagaggcat
    23821 tcctggtgcc atttctgttt catcatcccc attgcctgcc attcgaacat aaccgccaat
    23881 aggtaatagg cgaagcgtat atgttgtccc gtcttttgct tgatgcccat aaattttcgg
    23941 acccataccg atagcaaatt cgcgaacgag gattcctgat cgtttcgcaa agaagaaatg
    24001 accaaactca tgaacaatca ctaatatacc aaaaacgatg ataaatgtca gaatcgtttt
    24061 catagctttt ttctccttta cttgtttttt gtgtttttta taaaacaacg ataaaacact
    24121 ataattttac catagtatac caaagacacc aatagtatca atataatgaa aaataaaaac
    24181 ctgcgtcttt tatgaaattc acaaagaaac gcaggtatac ttactaaata atgccaaata
    24241 aatgcatgat aggaaataca aacagcaaac tgtcgaaacg gtctaagatt ccaccatggc
    24301 ctggtaagat atttcccgag tctttcacat cataatgacg tttgattgca gattcgacca
    24361 aatcaccaaa ttgtccgact gctgaaaaaa taatcgtcat cagaagcatg acaaacatac
    24421 catgattaaa tagttctttt gctgggtata gcaataaata aagaaatgcg actacaacag
    24481 cactaccaat accaccgagc gcaccttcaa tcgttttgtt gggcgaaata tcaggactta
    24541 acttatgctg accataacgt cgaccaacca tatatgctcc gatatcagtt gcccaaacaa
    24601 taaatagacc aaatatcaaa acagccaagc tttctgttcg tgcattgaca aaattctgga
    24661 aacctattcc cacatacaag ctgacaagca caggaaaacc tgcttcatca atcgtatacg
    24721 tatttttaga aataactgat gttcctaaaa gaatcataac tataagataa aataacataa
    24781 atgtacttac attctctgga agaaagaaaa accatctttc ttttggcaaa acaagtaaca
    24841 ctgcaccaac ggcggataaa actccttcaa aacttaagag tgtcaatcct ttcatccgaa
    24901 acagctcgta aactcctatt actgctaaga ttgctgctgt aagctcaacc gctatgcctc
    24961 cgatccatat aatcggaata aacaagacta gcgccacggc tgctgtgacc acacgttgtt
    25021 tcatgactga tcccctttct catcttctgt tttttttaca ccgccgaatc gacggtctcg
    25081 attttgataa gaggcgattg cttcttcaag atgcgcacca tcaaaatcag gccaaagcgc
    25141 ttttgtaaaa tacagctcac tatatgcgat ctgccataac agaaaattac taattcgctc
    25201 ttctccactt gtacggatca tcagctcagg atcttgtaac tctttaggca agaaacctgt
    25261 cattaaatgc ttagcaatca attcatcatc gatttcttct gcgtgtattt ctccttttgc
    25321 tacttcttcg gcaatttctt ggacagcagt cacgatctct gctctgcttc cataattcaa
    25381 agcaaaattc aataccattc cagtattgtt ttttgtttgc tcaattgcac gtcttacagc
    25441 atcttgcgta tgttctggca atacgttttc ataacccatg acatgaactt tgacattttc
    25501 tttaatcaat tctggtacga acgtatcaaa gaagtcgaca ggtagttgca tgagaaaact
    25561 tacttcatct tttggtcgct tccagttttc agtcgaaaag gcataaagcg tcaacacttt
    25621 cactccaagc cttgatgctt tttttgtgac tttctttact gtttccatgc cttctttatg
    25681 gccagcaact cgtggcaaac gacggttttg cgcccaacga ccattgccgt ccatgatgat
    25741 ggcaatgtgc tgaggaattg gtccatcggt attaaattga aattcgcttt tttcttgaat
    25801 atatttgttt ttttgcggaa aaaaacgtaa cattcttttt cctcctatac ttaaaagatt
    25861 cccactatct taagtattat agcaatatct aactgttttt cctatgaaat cattgttttt
    25921 ttatttaaaa actgaataat tttttctttt tttaattttt aaataaaaga aatataaata
    25981 aaaacagagg aagcggaatg atccgcccct ctgtttttat gattttatta aacttccaat
    26041 aattcttttt ctttatcagc agcgatctta tctacttctt tgatgctgtt atctgtcaat
    26101 gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg taatatcacc atttttttgt
    26161 tgttttttat attcatcgat cgcatcacga cggatgttac gaatcgcgat ttttgcattt
    26221 tctgcttctt ttttaacatc tttagctaat tcttttctgc gttcttctgt cagttgcggg
    26281 ataactaagc gaatgacatt tccatcattg gttggactga ttccgatatc acttgccata
    26341 atagcttttt caacatcttg aagaatgctc ttgtcaaaag gtgtgatcat taaaacacgt
    26401 gcttctggaa tttggattga tgccatttgg ttcaatggtg ttggcgcacc gtagtagttc
    26461 acagtaatac ggtccaaaag gctagcgttc gcacggcctg cgcggatttg cccaagttca
    26521 cgttgaagat tttgtgctgc ttttttcatt ttttcttttg cttctgtcat aattgcatct
    26581 gccattttta tttccccctt acagttgttc cgatattttc gcctaagatt gcacggcgaa
    26641 tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat atcattatcc atgcttagtg
    26701 aacttgcagt tgaatccatg acttgtaatc ctttggcaat aacttccaga tgagtcagtt
    26761 cttcaaattt tactgcattt gcatctactt tcggatcagc agaataaaca ccgtctacat
    26821 tgtttttagc catcaggata acatctgcgc cgatttctgc cgcgcgtaat gctgctgttg
    26881 tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa gataacgatc cgtccttttt
    26941 ctaaatgacg ttctgcttta cggcgaatat atggctctgc gatttgacgc atttcaatcg
    27001 aagtttgcac gcgtgtcggt acacccacgt tttccaacgt atcctgtaaa gctaaggcat
    27061 tcataactgt agctaacata cccatgtaat cagcttgagc acgttccatg cccatttgtg
    27121 ctccgatttg tccgcgccag atatttccgc cgcccacaac gattgccatt tcaacgccca
    27181 gctcgtgaac ttctttgatt tcttggatga tttctttgat tactggtggt ttgattccaa
    27241 atcctgcgtc cccagctaaa gcttctccac tcaattttaa gactacacgc tgatatttcg
    27301 gtgtgaccat gttcattcct ccaatatttt ctattgccat tttaccatac ttagatgatt
    27361 tcgacactct aagactggtt tttcttgttt tgcttaaaaa aagggagcgc acaaaccgtg
    27421 cgttcccgtc tgttattcaa cagaattatt ttttcacttg gctcataact tcttctacaa
    27481 agttatcttc gcgtttttcg ataccttcgc caacttcgaa acgtacgaat gttttaacag
    27541 ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc aggatcttta acgaatggtt
    27601 ggtccaccaa agcgatttct gctttgaatt tcttcaagcg tccttctacc attttttcaa
    27661 cgatattcgc tggtttgcct tcgttcaatg cttgttctgt aagaacagtt ttttcatgtt
    27721 ctaattcagc ttctggaatt tgtgattcgt ttacataacg aggattgata gctgctacgt
    27781 gcatagctac gtctcttgca actgtttcgt cagttgttcc atctagaaca gtcaatacgg
    27841 caatacgtcc gcccatatgc aagtatccac caaatgcagc attgtcgtct ttttctacaa
    27901 cttcaaagcg acggaagctg attttttctc cgataacttg agttgcttcg atcaagtcag
    27961 attcaattgt acctttatct gttttgattt tcattgcagc ttccatgtct gctggtttgt
    28021 tttcagcaac aagttctgca atttctttta ctaaatcttg gaacatttcg tttttagaaa
    28081 caaagtctgt ttctgagttt acttcaacga ttgctgcagt gttacctttc acagcaactg
    28141 aagccaatcc ttcagctgca atgcggtcat ttttcttcgc agcctttgcc attccttttt
    28201 cacgtaaaag atcaactgct ttttccatgt cgccttctac ttcaactaat gcttttttcg
    28261 catccatcat tcctacgcca gtcatttcgc gtagttcttt taccatttta gctgtaacgt
    28321 ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa aaaagctgct tcaaaggaga
    28381 gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt caaaattatt ctgctgaaga
    28441 attgtcgcct tcaacaacat ctacgatttc ttcgattgat gttgctgtgt tttcttctgt
    28501 gaaatcttct tcaactactt gatcttcacc ttggtttcct tcgatgaaag catcagccat
    28561 ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg tttgaaggga ttactacgtc
    28621 gatttcatct ggatcgcagt ttgtatcaac catagctacg attgggatat ttaatttgtg
    28681 tgcttcttga acagcaatac gttctttacg tgggtcaacg atgtacatta catctgggat
    28741 tcttggcata tcagcgatac cgcctaagaa tttttcaaga cgttcacgtt ctttgttcaa
    28801 accagcaact tcttttttag gtagaacttc aaaagttcca tcttcttcca ttgcattgat
    28861 ttgtttcaaa cggctgatac gtttttggat agtatcccag tttgtcaatg ttccgcctaa
    28921 ccaacgatgg ttaacgaagt attgtcctgc acgagttgct tcttctttga ttgcttcttg
    28981 tgcttgtttt tttgtaccta cgaataatgc tacgccgcct tcttcagcaa cgctcttcat
    29041 gtaatcataa gctgcatcta ctaatttaac tgttttttgc aagtcaatga tgtagattcc
    29101 gtttctttct gtgaagatat atttcttcat ttttggattc cagcgacgag tttggtgacc
    29161 aaagtgtacg ccggcttcta gtaattgttt catagaaatt actgccatgt ttgtttcctc
    29221 cgatttggtt ttatttttcc tcttcttatc ttctaccttg ccggcaaact ttttcaagca
    29281 cctaccgaca atccaataag aatgtggatt tgctgatgca taaagcaccc tcagctatta
    29341 tacagacaaa agatccgtat cgcaagagca aatatacttt tctgctcaac attcaatagt
    29401 ttacctgaaa gataaaaaga attcaagaaa aacagtagat ttctctttgt ttctttatta
    29461 tcctttttcc ataaaataat tttaggtata aaagacgaat attattgggc aatccttctt
    29521 ttttttgtta tgatacatgt gaaatctttc gtaaaggaga aagaaaatgc gcaaagctca
    29581 aagacatttg ctgattaaac aagtcattga agaattcccg atccgtacgc aagaagaact
    29641 attaaacaaa cttgggcatt atggcgttac cgccacgcag gcaacgattt ctcgagatat
    29701 ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc gtttcccgct tcgtattgtt
    29761 tcgcgaaaaa ggaactcctg agactaggac tgaggaagag gatcggctgg ttcaaatgat
    29821 tgaagacatt gtattgaaag tcgaacgagt ccactttttg acgatcgtca ataccttgcc
    29881 agacaatgct catttatttg catctgtttt agatgagatc aaacctccct ctattgtcag
    29941 tacaattgct ggattcgata cgatcatggt catctcggaa aatgaggagg acgcaaaacg
    30001 agtagaagaa tttcttcacc atccaactga agtatcactt ttttaatcag agcacgtatt
    30061 cctaatatgg aatgcgtgtt tttttatttt caatattttc cttattgaat aaacctttac
    30121 actctttaca aaaatacatc attttttatt caaatttttc aacaccttga ttgaatcaca
    30181 ataatcatca tttatattgg atgttaacaa gagcagcttc ttgctctttg tgtatttcaa
    30241 aaaagaaatg aaaggaaatc atatgtataa attattaact tctggaccat tgacgacttc
    30301 tgaaacagtg aaaaatgcta tgctgatcga tcattgtact tgggatcaag aatacaaaga
    30361 aattacacaa tggataagaa aaaaattatt ggatcttgct caagtatcgg aaggaatata
    30421 cacaacggtc ttaatgcaag gtagcagctc cttcggggta gaatcggtat taagttctgt
    30481 gatcaggcca gaagatactg tactgatttg ttcaaacggc gcatatagac aacgaatgat
    30541 caacatgtgc gaatgtctga aactgaacta taccgtttat gaggtatcgg aacatcaaat
    30601 cctccaagct catgtgatta cacagctgat tgaagagaat ccgtctatct ccgcactagc
    30661 aatggtccat agcgagacta cttccggtat tttgaataat ttggaagaga ttgctgctgt
    30721 cacacaagaa agagatcttt tgtttatagt ggacgcgatg tcaagctttg gtgggatacc
    30781 gatttgtgta gccgaactag ggattgattt tttgatttcc agctcaaaca aatgtattca
    30841 aggtgttcca ggcttttctt ttgtacttgc taataaagcg gaactggaaa aacgaaaaaa
    30901 tgttagccga agtttgtcac ttgatctata tgaccagtac cgcgtgatgg aaaacgagaa
    30961 tggcaaatgg cgtttcactt cccctaccca tacggttttg gcttttcaac aagcgctgaa
    31021 ggaactagag gcagaaggag gaatcgaaac tcgatattca cgttatctcg ccaataatca
    31081 tgtgctacga caaaaaatga cagagatggg gttccagcct ttcattcaag aatatcaggg
    31141 gccattcatc acctcttttc tttaccctaa ggactggcga tttgatttta atcattttta
    31201 tcagtattta aagcaaaatg gatttgtgat ctatcccggg aaaatcagcg atcatgaatg
    31261 ttttcgtatc ggaaatattg gcgagatcta tccggaagat attttggaac tgacagcaat
    31321 tatcaaagac tataaggaga acgttaatga ttaaaactgt aatttttgat tgggcaggaa
    31381 caactgtgga ctttggctgt atggctcctg tccacgcttt tagaaatgct tttctagaaa
    31441 aaggaatcca actgactgac aaagaaatcc gctaaccgat gggaaaatta aaatgggatc
    31501 atatccaaca gcttctttcc ctcccttctg tcaaaaaaca atggatagct atttatggac
    31561 aactacctca ggaaaaagag gtggaggaat tgtatcaaca atttgaacat tatctgttta
    31621 aagatttggt caagcattct accttgaaac ccgacacatt ggaaacgatc gaacggttga
    31681 gaaacgctgg gatcaatatt ggttccacga atggatttaa tgctcctatg atgacaatcg
    31741 tagcagaaac cgcaaaaaaa gaaaggtatt caccagactt catggcaact tttgaagacg
    31801 tcgaagggta tggtcgaccg tttccttata tgatccataa aaacatgcag tacttcaaaa
    31861 acaagtcggt tgatgaagta atcaaagtcg gagatacggt ctcagatatc caggaaggga
    31921 aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag ttcgctaatg gggatttctt
    31981 atgatgagta ccaaaaatta gagatgggga aaaagatcgt ttaaaacagt ctgttgctct
    32041 tagattccaa caagccggcg ctgatatttg tgtaaacaat ttaaaagagt taacagaata
    32101 cattttgtac gctgacatga atccagaatg acttttatac aaaataagag gttgtgaaaa
    32161 agctgtcctg tatcaagtaa taaaaacagc caagcaaaaa tagctcctca tatttttcgt
    32221 ttggttaggc ttattaccgc agatgcaagc ttttgaacac cgtttattcg aaaaaaaaaa
    32281 gggagctgtg acacgacttt tgtcacagtc cccttatttg caaacaaaca gtgtttaaga
    32341 gacaacctct ccactaaacg gtgttcattc agctgactct cggtatttgc tcaaaaaacg
    32401 ataaaatttg aaaagctatt ttctcttttg tttctctaat actcggatca gaacgctgat
    32461 ttcacattct ctttttctta catcttatct ggtgcatgaa gtcctagcaa acgaaggtct
    32521 tctttcaata atacagtcac tgcataaact agagctaagc gtgcttcttt ttgttcatca
    32581 tcagctaaaa tcttcgtatg agcatagtat ttgttgaatg cttgtgctaa tttgattgca
    32641 tgtttcgcaa tcactgacgg ttcgtatttt tccccagcag acaagaccgt ttcagggtat
    32701 ttttgaacta atttaaccac ttcccagctg gtatcgtcat tcaatgcata gtctgctgtt
    32761 tctgaaggga caaatcctgc tttttccaac aggctgactg cacgagcatg tgtatattgc
    32821 acataaggtc cagtttctcc ttcaaatcga acaacttctt ccaggttaaa gtcaaatgta
    32881 ttcagtcgat cgtttttcaa atcgtggaaa atgactgccc caaccccaac ttgtttagct
    32941 acagcatctt tgttttccaa atcagggttt ttctcgctga tttgttcttt agcagattgg
    33001 attgcttcat ttaatacttc ttctaataag acgatctttc ctttacgagt tgataatttt
    33061 ttaccacctt gcgtgatcaa accaaatgga atatggtgca tgtcgtcaga ccagtcaaag
    33121 cccatttcct tcaagacagc tttcaactgt ttaaaatgat agctttgttc attccctact
    33181 acatatagag attgtttgaa gtcgtaagta cgtttacggt acaatgcagc agctaagtca
    33241 cgtgtaatgt atagtgtcgc accgtctgac ttcttaatca acgctggatt caggtcataa
    33301 gcagataggt caacgatctc tgcaccttta tcctcgttca gcaaatgttt ttcttctaaa
    33361 agtttgacga tttcatccat cttgtcattg tagaaagctt caccgttcaa cgaatcgaaa
    33421 cgtacttcca gcagatcata gattttattg aattctttca tcgattcatc acggaaccat
    33481 tgccataatt gaatagcctc tttatcgcct tcttccagac gtttgaacca agcacgagct
    33541 tcttcattta attctggttc tgtttcagct acttcatgga attggacgta taaacgaagc
    33601 aattcattga ttggttctgc tttaacagct tcttctgtac cccatttttt gtaagcgacg
    33661 atcagttttc caaactgtgt tccccagtca cctaaatggt tgatgcggat tggctgataa
    33721 ccgatttttt ccataatgaa accgatcgaa ttaccgataa ctgtcgaacg caaatgtccc
    33781 attgagattg gtttggcaat attaggagaa gacatgtcga ttggtactgt tccttgattc
    33841 ccgatgttgc tatccccata atgttctttt tctttcacta ctgtttgcaa aacttttttg
    33901 ctgataagtt ctttattcat gaaaaagttc aagtaaggtc cgacaacttc gattttttca
    33961 aagttggcag aatcgatttt ttctgctaaa tctgcagcga tttgctgtgg cgcttttcgg
    34021 taaacttttg ctaatgaaaa ggctggaaat gcaacatctc cgtgttcagc tgattttgga
    34081 ttttctagta attgctcgac ttgttccagt gttaaatcat ctttgacagc gtcatagaca
    34141 gcttttgcga caagatcttt attattcatc tttattcctc ctaaagtgtt cccttgattg
    34201 ttaaacaaaa aaaatctcta gcgacggcat acttagtatg ccatcactag agacgagatt
    34261 tcccgcggta ccactccaat tgtcctaaaa aaggaccagc tccatctgat atcggtagac
    34321 gaccgtctgt ttaaaacaga attctccaag tgcgcttcgt tgtatcttct tcattcggct
    34381 tccaccactt ccgaattcgc tagccaagaa tgatacaagt actctcttgt tcaacaaatc
    34441 ttagtcttat taaactttct tgaattatat cagaaaaaaa aacgaaaggc tagtcgtttc
    34501 ataaaaaaac aatccagatg gcctaaagga gaagaaatac cacctggata gctataaatc
    34561 atttcgtaaa tacgaaagac ttaacaaatt aatcagctac gataatcgtt ccttcttcag
    34621 aagctaaaag attctcgata ttttctaaag aagtgatgat tgccttagcg tttggttttg
    34681 cttcaacaaa tgcaatagct gcttctactt tcggaagcat gcttcctgga gcgaattgct
    34741 tttcatcaat gtattgtttc atttctgaaa cagtaacagt ttctaatttc ttttgatctg
    34801 gtttttggta attgacatac acattgtcta ctcctgtcaa tacgatcagc aaatccgcat
    34861 cgatgatttc ggctaatttt tctgaagcaa aatctttatc gattacggct tctcgtcctt
    34921 ctaatccagt agctgtttct acaacaggaa tcccaccgcc accaacagag actgtgataa
    34981 ctccttgatc gaccagcgtt tcgatgacac gtgcttcttt aatcgagatg ggtttagggg
    35041 aagcgactac ttttctccat ccacgtccag catcttcttt gaatgtcaca gtggagtcag
    35101 cattcatttg ttctttggct tcttcttccg tgtagaatgg accgactggt ttacttggat
    35161 ttttgaatga aggatcattt tcatccacaa taacttgagt gactaaagaa accacatctt
    35221 tatcgatccc tttttccttc agtacttcgc ccatggcgtt ttgtaaccag taaccgatag
    35281 atccttctgt cattgcaaca catgtatcta aaggcattgc cggtgttttc tcagaatcag
    35341 cagcttgctg ctgaatcaat aggttaccga cttgcggacc atttccgtgg gagatgatca
    35401 attcatctcc ttgttcgata aatttcacta aatactttgc tgtttccatt aacgcttctt
    35461 gttgggcttt tgcacttgca tccgtagaca agatggcatt gccccctaaa gcgacaacta
    35521 cttttcgttt ggccatttca ttcgtccttt cttcagttct accgaatttt ctagataaca
    35581 aaacgagcca gcgttttgtg attttccctc aatgctgact cgttttttcg tgagatgaat
    35641 gtggttatgc ttaaacgcga gggataaaca agttacctaa tgttgctgcc atgatcgctt
    35701 tgattgagtg catacgattt tctgcttggt caaattgacg agcatatttg ctgcggaaga
    35761 cttcatctgt tacttccatt tcagtgatgc caaagcgttc tttcatttgt tcaccgtaaa
    35821 cagtgtttgt atcatggaaa gctggcaagc agtgcaagaa gatcaaacga tctgtgttgt
    35881 gtgttttttc taccatttcc atattgattt ggtaaggttt caacaatttg atacgttctt
    35941 cgaatttatc ttcttcaccc attgataccc atacatcaga ataaaggacg tctgctccgt
    36001 ctacaccttt atcaacatcg tcggtaatca tcaattgtgc accggatttt tcagcaaagc
    36061 cttctgccat tttgacgatt tcttcttcag gttgtaattc ttttggtgca acgatacgca
    36121 tattcgctcc taaaattgca cctgtgacta ataaagagtt agccatattg tttcgaccat
    36181 ctccgcagta agcaacagtg ataccttcta ctgttccaaa gttttcttgg atagttaaaa
    36241 agtcagcgat catttgtgtt ggatgccatt catcagtcaa gccattccaa actggaacac
    36301 cagagaattc tgctagttcc tctaccattt tttgactgaa tccacggaat tcgattccgt
    36361 caaacatacg tcctagtact ttagctgtat cttctgtgga ttctttttta cctaattgga
    36421 tatcatttgc acctagatat tcaggatgtg cacctagatc gatcgctgca gtagtaaatg
    36481 cagaacgagt acgtgtagat gttttttcaa ataaaagcgc aatatttttt ccttctagat
    36541 agtgatgtgg gataccacgt tttttcaagt ctttcaagtg ttctgaaaaa tcgatcaaat
    36601 attgtaattc ttcttttgta aagtcttttt ctgctaataa gcttcttcct tggaatactg
    36661 attctttcat attaaacatt ctcctttaga ttgtttttat ttaagattaa agaggaaatc
    36721 ccgacggcag ctgacagtaa gactgccgtc aggaaacaaa ttacttcaag tcttcacgga
    36781 caagtggttg gctcatgcag cgtggaccac cacgacctcg tgacaattca cttgaattga
    36841 tttctaacac tttgatgcca tagctacgaa gcaattcgtt cgatacataa tttcggttat
    36901 aagtgactac aacacctgga gcgattgcca atgtgtttga tccatcattc cattgttctc
    36961 gaggtgcaac gatctcatct ccattaccag ttgggatcag tacaagatca tctaatccaa
    37021 gagcagcttt catcgtttcg tgtaagttat ctgaatgagt aatcttgata tcatcaccat
    37081 ctggttcgat tgtaaagaca tccatcttac cgtctttact ttgaattgct ggatggatag
    37141 tgaatttatc gtgatctacc attgtaaata cggtatccaa atgcatcatt gcacggttgt
    37201 tcggaatttt gattgccaac actttttcaa atcctgaatt ttttgcgaat aggtggcgtg
    37261 ctaatttttc taaagctttc gcattagttc gttgagaaat cccaacagct actactttat
    37321 cgcttaagat caattcgtct ccgccttcga tatgatctgg attttcacga tccaaccata
    37381 cttcgattcc tttatttgca aatcttggat gatgtttcaa aatatattct gtaaacatcg
    37441 attcacgacg acgtgcttca aaagtcatct tattgactgt catcccattt cccattgatg
    37501 cggaagggtc gcgtgtaaag tacaagtttg gcattgggtc catgtaaaat ggatagtcat
    37561 cgtctgctga cagatcatat agactgctag aacgtacttc gatatctttt gtacgaaccc
    37621 cagccatgat tttatctacc atttcttgcg tttccattga tagaaggaac tcatgaagac
    37681 cctctcttac agcattcgat gcaatatgag attcatccaa cattttattc aagaattgtt
    37741 ctttgacatt gcctgcgtca atcgcttctg ccgctaattt ttccaagtaa agagtctcga
    37801 cgccttcatt ttgcaatgtc ttcgcaaagt tgtcatgttc ttcttgagca atcggaagat
    37861 atggaatatc atcgaacaac agacgatcca taatatctgg tgtcaaattt tccacttctt
    37921 gtccaggccg tttcagtaaa actgtcttta atttccctat ttcagagaaa acgtgaatag
    37981 gtttatccat gttgtgttgc ctccttcttt ttgattacat gtataggata tcctcctttt
    38041 gtaatcactt tcataatttt gtctcattca aaatgagaca ttcctcacat taatattcga
    38101 taattaaata attaaacgtt tttctatttt taagcgtaat ttattcattt tttattctgt
    38161 atacactttc aaaaaaatat ttattcattg aaaaaatttt tttgaataaa ttaaaaaaat
    38221 aaattatatt atcgttgtta gcgtttacta tatgtattat tgttgttttt tatacacaaa
    38281 tcattcgctt caaaacaaat tattcaatac cattgtatat tttttacata ataacaaatt
    38341 atatttgtaa agtattaaaa cttgtttcta atgttggtat gttaaaactt tacaaattct
    38401 ttaaaaaaag tgacaataaa tatagtgaac aataaggaga ggacttttta atgcgtgtta
    38461 ataaaatcga ttttcacttt tcaaaactca gatatcaacc tgattttgaa catttctcgg
    38521 atgaagagtt ccaacagatc aaggaacata ctgttcttcg ttcttataaa aaaggacaga
    38581 tccttttcga cgatggtgat cccagacaac ggttgtatat cttgaccaaa ggactcgttc
    38641 gtttagaacg ttatgatgaa agtgcaactt attactacta tgactatgtg aatacaaata
    38701 acctttttcc tatgtcagga atgtttggag aagagaccta cacttataca gctcaagcga
    38761 tgactgatat tgaaacattc taccttcctg tttcctacta tgaaaaatta gcacgaaaaa
    38821 atcccgaaca gttgatctat atgatacaaa aaatttctaa agtagttgaa atacatgaat
    38881 tgcgtatcca aatcggattg acctctagcg cctttgaccg ggtaaaacaa aatttattca
    38941 ttttgaaaga agaattgggc gtaccaacaa aagatggtca tatcaccatt ccttatccga
    39001 tcaccttaaa agaattagca gtgaatagcg gcacgacacg tgaaactgct ggacaagtaa
    39061 tcaaacaact acgtgattcc gggctgttag attatgacaa aaagcgtttt actttctgta
    39121 agacagctac tactccagct atgagagaat aacgcgaaca aaaataagca gtgaccctga
    39181 taaatatcag ggtcactgct tattttcctc cctaaaactt ctgaaagatc cggcagtttt
    39241 agatcactgg acaagactca aagattttct atgtgtgttt cagttatgta atattcactg
    39301 tttgcaaaaa atactgttag attaactaga tgaagcgtct tgtcctcatc cgatctagat
    39361 tattcgatat tcctcgacaa taaacgatta ctcagtgagg gcaatcagag gaacggataa
    39421 tgataaataa gctgtaaaaa atagcaaaat aacaataatg attaaaagta tgtaaaaaat
    39481 agggctttga caaaaacgtg tcacagccct atttcgatta aacggtgtgt acctgtcaac
    39541 tcttcggtca caagtcataa tgttcataaa catgaggagc tgttttttga aattgttcct
    39601 tgtgaatcag agttaaacga caggcttacg aactcttgat taaacggcgt tcaaaagctt
    39661 gcatacgcgg taataagaac agccaggtca aaaacatgag aagccgtttt tcctgggctg
    39721 ttcttattac ttgatgcagg gcagcttttt cacaacctct ttattcagat aaaaccaagc
    39781 ttggatcagc attcaactga tagctagcaa aatttctttt ttgcatttcc acatgtgctg
    39841 ctgctccaat cattgcagca ttatctccac aaagtcgaag agggggaatc actagttcta
    39901 cctcagggag tttagctgcc aaagcatcct gcaatccttc acgcaaccct tgattggccg
    39961 ctacacctcc agctataatc agttgcttga ctggataatt ttgacaagct cgaagtgttt
    40021 tagtaatcaa tacatcgatc acacttgctt gaaagctagc tgctaaatca tttttgtcta
    40081 gatcttctcc acgctgttgt gcattatgca ccaaattgat aaatgcactt tttaatccgc
    40141 taaaactgaa atcataatta tcttcatgga tcatcgctcg cggaaaatgg taattatctt
    40201 ttccctgatg agctagctga tcgatttctt ttccgcttgg gtaagaaaga cctaatactc
    40261 ttccaacttt gtcataagct tctcctgctg cgtcatctct tgtctcccca atgatttcat
    40321 atgatccatc ttcttgcata tagactaatt ctgtatgtcc tccgctaaca agaagtgcca
    40381 tcaatggaaa ctggaatggt ttaaccagac gggctgcata gatatgccct gccatatggt
    40441 ttacaggaat aagcggcaat tggtgtgccc aagcaaaagc cttagctgca gaaataccaa
    40501 tcagcaacga gccgacaagt cctggtccat aagtgacagc gactgccgat aaatcttctg
    40561 ccgacacacc agcttctacc agtgcatctt ccaagcataa ggtgatttgt tctacgtgat
    40621 ggcggctagc tacttcaggt actacgccac caaaacgttt atgactgttt atttgagaag
    40681 caacgatgtt agataagatc tctgttccat ttctaacgac cgctacactc gtttcatcac
    40741 aacttgattc aatcgccaga atcaattctt cattcatttc atcgtctccg tttttaactt
    40801 tctgctcata atgatcgcat cttccgtcgg attgcgataa tatgatttcc gtttacctaa
    40861 tatacgaaac ttttctgatt cataaagttt tcttgctgct tcattagata gacgtacttc
    40921 taaaaaaaca tgcagcgaat cttttatttg ttccgtaatc agtaattgta acaaatgccg
    40981 tgcatgccct tttccttgtt ctgaaactgc aacagcaata tttgtgatct cgacttcatc
    41041 tattactttc gagtatccaa taaagccaca gatctggtta tcttcagcta aaagcagata
    41101 atcagagtga ggctgttgga tgtctgccaa aaactgcatt ttcgtccaag gtgaaccatg
    41161 tggataagca ttttcgctaa tcatccatac gcattctgcc aagtacgctt catcaaaatc
    41221 tttttttctg caaatcaact aatctcactc attttctaaa agttttatca tatccaacgc
    41281 atcttctttt gtttcagtgt aatatctttt tttgatcgtt gttgcttgaa accccaattt
    41341 ccgataaagt ctttgtgcat cttgattact catacgcact tctaatgaca tcgtctcaca
    41401 gcgattcatt atagcaaagt tctcgatttc gtcaataagc agcgaaccga ttcgtttacg
    41461 ctgatatgcc ggtcgaacgg caatattcgt gatatggcaa tctaaaccga acgctcttga
    41521 accgataaaa ccaatcattc ttccattatc aaagatacct agatatagat gaggaagcgg
    41581 tgacttcaat tctgatataa aggcactttt tgtccatggc aattcgccat tatagacttc
    41641 tcgttcgaca tccagcagct ctttgatatc ttctgtagtc aattctctta gtacgtaacg
    41701 acgatcgatt tgttcgactg ttttttctgt ataaatcatt ttatcttgaa aaaagcttct
    41761 ggcatacgct ctaaattttt tcaacataac tttcgtctcc aggtgtgtgc gtctccaacc
    41821 atttttcttc tgcttctact cgttttaaat agcgaggaag aaaagcttgt ttctctgcaa
    41881 ctggttcaac taaagcacct aattgagcca cagttacacc acttggaata tcccatgctg
    41941 gaactgtatt aatcatcgca ctaggcaata tttcctttat ttcagagaag aatttgtgac
    42001 aatcactccc gacgaaataa atagcttcat tcagcttttg tagttgtgtg aacaaatcag
    42061 aagcagaaat atgtacatct tcaagtacag tttctaatct attttctttc cagcggtatg
    42121 ccccagcgta tacatttttt cttcgagcat caaacatggg cacaataata ttatccacac
    42181 cgatgcaatt agccgcgatg gttttcagac tagatactcc tactagctct ttatctaatg
    42241 tataagcaat cgtttttgct gtcgttacac ctatacgaag ccctgtataa gaaccgggac
    42301 catcagaaac cgcgattcgg tcaatgtctt ttggacttat ttgaagatct gcaaacaatt
    42361 ggtcgattgc aggcatcagt gttacactgt ggttgcgttt gatatttgtt tgtatttgtc
    42421 caagaatttg ttcgtcttct accacaccga tcgccaaagt ttggtttgca gtatctattc
    42481 ctaatgtaat catatatttg atcctttctg ctatgacatt ctcgccttcc attgtagcat
    42541 acttttttat tctgaggatg aaaataccaa aggcaaaact agtacaataa tacatgatta
    42601 tctgctggcg ggcaaatttt gccccttcct gaaacacaaa aaagctgcgg tatcactcca
    42661 ttttcccaca gcttttccat cttttatttc gttgattctc gaataatcaa ctctgtttcc
    42721 acaataatct ttcttgaaac cggtgctttg gaattactta attgaagaat cgtctccact
    42781 gctagctctc ccatccattc ggtataaact tttacagtag aaagcgaggg cgttacatat
    42841 ttcgctacac tgacatcatt gaagcccatc acagaaatat cttctggtac cactaaacct
    42901 ttttcttgaa tcgctttcag tgcgccaatc gctaatgcat cattagctgc aaaaagcgca
    42961 tcaggaacat gcggattcgt ttttaaatat tgcttcactg cttgatatcc tgactcgaca
    43021 gaaaaatctg cttcgataat tggaccttcg tcgtagcctt tttctgccaa aacttgttga
    43081 aatgccataa ttctgggatc ttttagccgc tgatggtttt tcttcgtata ttctgttcca
    43141 gcaagcatag cgatatgttg cgctttatgg gagacaaagt gttcaatgac tttttgaaca
    43201 cttgacttaa agtcgacaac tagagagtcg attccttgag aagtgccgtc agaatctacc
    43261 aaaagcaagg cattttggga tcctttcatt tctaataact gagcttcgtc gaattttcct
    43321 agtgcgatcg ttccatctgc cggaagatca ctaatggaat cccacgtttc tttcaataaa
    43381 gtaacgtttg cttcttctgc ctttttttcg attcctaggc gaatagataa ataataaaga
    43441 tcttcaagct cttccgtatc gtcgtaccac tggatcaggc gaagcgtttg cttagtattt
    43501 gctgcatttt tacgatgttt cgtataattt aagcgttctg ctgcttcaaa aattttttgc
    43561 tttgtggcta agccaacgga aagatcagga tcatagttga gaactcttga aacagtagca
    43621 ggagaaactc ctgccaactg cgcaatgtct ttaattgttg ccatttgtct ctcctccttt
    43681 tttacgttta taaaatcgca gtaaatcgtt caaacgctgc ctgtcctttt tcatctcgct
    43741 tgaatactcc agcgtcttcc agtacacgtg caaaaacctg acctacagat ttttgtacga
    43801 catcggtgac cgtatctttc gtcaaatcag gatgttcttt ttttaattgt tctgcccacg
    43861 gacgatgata ttcagccatc tggttttctt ctcctaataa gaaatgctct acttctacta
    43921 gttctggttt caaacgaggt ggtaaaacag caagccccat tacttcgatc aacccaatgt
    43981 tctccttttt gatatgttgg acatctttat gtggatgaaa aatcccatca ggatgttctt
    44041 ctgaaacatt gttgtctcga aggacaaggt ccaactcaaa gtaattgtcc cttcttcgtg
    44101 caattggcgt aatcgtatgg tgtggtgtac catctgctga aaaagctctg atagatactg
    44161 tttcatccga atatgctttc catttttcca atactgagtt agctgcttca ataagcaagt
    44221 ttttctctgt tgattgcaaa cggatcacag acatcggcca tttcacgact cctgcgatga
    44281 cttgcggata atcttctagt ttgataagtt tttctatcgg tgcttttgcc ataggaaatt
    44341 catgacgtcc tgcctgataa tgatcatgag aaagaatcga tcctccaaca attggtaagt
    44401 cagcattcga accaacaaag taatgaggca agacttcagt aatccgaagc agtctagcaa
    44461 atgtttcctt tgtgattttc atcgggcggt gttgttctga taaaatgatc gaatgttcat
    44521 tgtaataagc ataaggggaa tattggaatc cccagctttc accgtctaga ttcattcgaa
    44581 taatccggtg attggtgcgg gctggatagt tcaagcgacc tctatatcct tcgttttcca
    44641 tgcaaagcat gcaggtagga tagtctactt ttaccgcctc gcgttctgct gcgatttgtt
    44701 ttggatcttt ttctggctta gataaattga ttgtgatttc cagttcacca tactccgact
    44761 ctgccggaaa tttgatgttt tttgcgatgg ctcttgtttt gatgtagtca tttttcttac
    44821 ttaaattaaa gaaatactca gttgcttcct ctgggctttt cgaatagtgc tgtgcaaaga
    44881 atgcattgac gactgaaggt ggcggtgtga gaaaatccat taattgcgct tcaaaaatct
    44941 cttgttctgc tggcaattct gaaagaacac cattttctct tgccttagcg acaagctgat
    45001 ccaataagtc tacagattct tccttaactg gtcttacttc aatgctttct agagcatctt
    45061 ctcctaccat ccctaaaaga cgattctgta aatataagcg gtccatttcc atccatccgc
    45121 cagcttcgat cgcaagtgtg gcaaaatcac aaatcgtttg actgattgac atatctcatt
    45181 cccctattct tcataaccat ttggatggct gacatgccaa tcccatgctg ttttgataat
    45241 cgctttgata tctgtgtatt caggtttcca gcccagaatc tctctcgctt tttcacttga
    45301 agcgactaat cggctaggat ctccagctct tcttggtgct atttctgctg gaatttcttt
    45361 tcctgtcact tctctagctg cttctagcat ttccttgact gagtatcctt tgctgctgcc
    45421 taaattgaag aagttgcttt catttccttc tttcaagtat tccaaagcta aaatatgtgc
    45481 agcaatcaaa tcttctactt gaacataatc tctgatacat gttccatctg gtgtatcata
    45541 atcgtctcca taaacagcca aggcttttct ttgaccaaga gctacttgta aaatgattgg
    45601 gacaagatgc gtttctggtg tatgatcttc tccgatagat gcatctgctt ttgctccggc
    45661 tacattgaag tagcgcaaag cgacatagcg catgccatat gcttggtcac accacttcat
    45721 cattttttcc atcatcaatt tactttcacc atacggattt ttaggattag ctggtgtatc
    45781 ttctgtgatt ggagactctt tcggctctcc ataagttgct gcagtagaag agaatacgat
    45841 tttattcacg ttgaactcgt gcatgacttc aagtaagatt tgcataccgt atacgttgtt
    45901 gttgaaatac atcaatggtt tttcgacaga ttctcctact aaagagcttg cagcaaaatg
    45961 gattactcct tcaatcggtt ccttttcaaa tacggaacgt agaaattctt tatcccggat
    46021 gtctccttca taaaaatgag catctggatg tactgcttgt ttgtgacctg tgagcaaatt
    46081 atctaccaca gctacttgat accccttttg aactagctgg tctacagcgt gcgaaccgat
    46141 ataaccggct ccgcctagta ctaaaattgt cataaaaaac actcctttga ttagtaaaat
    46201 tgtgtttgtt gattctatat aatttaaaaa acgaagttta cttttatggt gaaaacaaac
    46261 aaagtaaaat ttcgtaaatt catatggtaa atttataata aaacatttag taaacatttt
    46321 caagggtttt ttgcaaaggt ttacaaacaa acgtaaaact agcctttttt tctcttttgt
    46381 tccataatag atataacaaa taataaatga ggtggattca atgaaaaaat ttgtatctgg
    46441 aatattagta ggaagtctgg caacagccgc tgccgttgct ggtttggttg cttctgtgaa
    46501 aaaaacagtg atcgatccaa ttgacgaaaa agaagcaatg atcgaagaaa accgtaaaaa
    46561 agcaatgcgt aaacgcgttt ctcgttaata attatttaaa aatacgcatg aagactttct
    46621 aaaaaacaga taagtcatca tgcgtatttt tatttgtcag tcaatataag ttgtgctatt
    46681 ttatctgcct gtctcagatt ccatggatct gtataaggtc tagctactgc tgcagttagc
    46741 caatccacac cttcaacagg tattccatag caataaaagt cagactggat ttcccctgaa
    46801 gcatcaatca cgcgattcgt acctcgctca acatctatag cttctgaatg ataacttcct
    46861 gtattatctg aaaatgaaaa agggcgaaca agtttgtttt ccttcaaatt ttttatgaca
    46921 ggattacttg aacgagaaaa gcttgtttgt ggcaatcgag cttcaatcaa atagcgactg
    46981 ctgatttctt tatcttgtag agaaataaca tagcggttgt gcttttgctg aatatcaaat
    47041 ggcggttcga tcaaatgaaa aatacccgca tctatcagtg ctgctaattc tttcgtccga
    47101 atgattggcg gaccgatcgt taaaaagcta tttagatgag taaaccatcc ccatagtatt
    47161 tctttgtatt ccttagcaga aaaaacgtgc cattcaatag cctgccggat tggatcacgc
    47221 cagtctttta atgcatcaaa tgttgaagca aatgctcctg tgcaattgcc tttttccgct
    47281 tcttttatct gcccttcaat aaatattcgg ctagcttctg aaaagggctc attctgatag
    47341 gcaagaggag tttctaaata cgaccaatcc catctataag ggattagtgc tggatgcttt
    47401 ccgagacact cctctgaaga gagggagaga aaatcatgct caaaattttt ctttggaatc
    47461 ggcaagtgat attcttcgat gattttcttg taataaaaca actcaacgtc ttttttcaga
    47521 tagtcaaaaa atgtttcgcc agtcaaaaat cccgactgat gccattgctc caggttttct
    47581 tttgttagta accgtggcca tgccattgct ccgccttgct tttgatttct tcctcgaggg
    47641 taataaggga gcccccttct tgatccactg tatacaatcg gttccttgcc tgatggatga
    47701 tagaccagtt ttcccttttc gttctcgaag cgccctcctc ttgatactgt aaacaatccg
    47761 acataatcaa aaaaacttaa gcctagacct cttaaaaaga cattttcttt aggcggtatc
    47821 ttcgaaagat ctacatctgc aggattagaa ggaagctgat acagtaaaac atttttcttt
    47881 gcgtagtcta cccacactct ttcttcttct gtctcatcat tttcccagtg accgcttgct
    47941 aaaacaagct gatcgataga atagctttgc tgatctgtct gtaaaagata accatctttt
    48001 cttttgctta ctttttttac taaagaataa acaaactgaa tagaagctgg aaattcttct
    48061 tgcaactttg agaaaaacca gcgttgatag agtccgtata aacatcgagt agattgctga
    48121 tctttttcca gacgattgat ttcttctata attagttgct tatttttggt taccgtctgt
    48181 tcgatataat ctgtagcagg tcctttactc cattgaaaca agttgggtcc ctgtgttacc
    48241 aatcctccac tggacaatgt ttcatctgta aaaagcgtca cttgttgaga aacagaattc
    48301 attaataact ccggtggctg attcaaccgc caaactcgac ctccaggacc attgggatcg
    48361 aaaagaaaaa gttcaagaga atgtctgtcc tgattattat ggagaatcct ttctgctaca
    48421 cttaatcctc taggtccggc accaatgatc cctattttca tttgcatgcc tccatttcga
    48481 taaatttttt caataaaaca gcatggttct gatgttcatt ttttgcacca taaacaaaag
    48541 taatgactgg atgttctttc ataagttgac tgagtttaaa aatagcttgc ttcttttctt
    48601 cttcgaaaat caattcttgc tggtatttct ttgcaaatga agcaaatcgt tctggtacat
    48661 ggtcaaaagt tttgcgtgct tcattactag gtgcaatttc tttcaaccac agatctaact
    48721 gcgctttttc ttttgaaatt cctcgtggcc agaatctatc cacgagtatt ctatagccat
    48781 cctctttttc agcatcaagg taaacacgtt ttaatttgat catagttgtt tccttctttc
    48841 taccttttcg cttagcttat atatgtagat aatagcacaa aataaaaaaa atgaacggca
    48901 caactatcca ttgcgccgtt catgtgatct tggtcaaaat ctaatgattg attcggtttt
    48961 taaagctgtc atacaatcat ctgttttata cttttttact tttgattttt ccagaccatc
    49021 cgtcatatcc acccttaagt aaataaatct cttgataacc tgctttacgt aatttatttg
    49081 ctgtacggat gctcaaactt ttcttttgat cgtaaatata gacaggctgg tcttttcgaa
    49141 tagatcctaa tgaatctttc aaaacagtgt aagggatgtt tcttgcacct aaaatatgcc
    49201 cagcatcaaa cacatctttt tcgcgaacat cgattacttg tgcttttctc attccttctc
    49261 gaaattcttc ttctgtcaaa gtcgttgctg aacgtttggc cattactcgt agatagactt
    49321 cccaaaggat gattgcaagc acaatcaata gcaaaatgat attaattacc cataaaacca
    49381 tgtaatgcct ccgttttttt aagcaaattt caaggctaat gaggcagcac caatgacacc
    49441 agcttcatta ccaagctctg ctaatttgat ttttgttgat tctcttactt gcgggaaagt
    49501 aaattcttta aaatatttct ctacacggct acgtaaaaat tctcctgctg ccgatactcc
    49561 tccacctaac acgatacttg acggatttaa tgtattcccc aagtttccgc aagctaaacc
    49621 taagtagaag catacgcgat caacaaccat caatgcaaac ggatcgtctt cttgagccat
    49681 ttcaaagata tctttacttg ttacttcttc tccgttgtct agcattgctt tcagttttga
    49741 atcccctgcg tattcttctg ccaagaaacg acctaggcgt accacacctg tagcgctaga
    49801 tacagtttct aaacatccgc gtttaccgca agtacattcg aacccttcag gatccacagt
    49861 gatatgtccg atttctcctc cagctccgct cacgccgtga atcaaatttc cgccagcaac
    49921 gatacctccg ccaacacctg ttcctagagt aacgaataca acgtctggat cgttttctcc
    49981 agcacctttc catcgttcac ctaaagcagc aacattcgcg tcattatcga tagcgaattt
    50041 gattcctgtt cctgcctcga tcagtttttt cacaaattga acttctgtcc agtttaagtt
    50101 atacgcacca ataaccgttc cagcttcgct gtccacgctt cctggggtac ccatgccgat
    50161 tccgataaag tcttcggctt tcatattata taaattcaaa cgatgattga ttgattcaat
    50221 gatttcagga acgatatgct taccatcatc caaaatattg gtatcgatgc tccatttttg
    50281 ctgaatctct ccttctggtg ttaaaattgc aaattttgct gttgttccac ctaaatcaat
    50341 cccaataatc ttcttgtcca ttacaaattt cctttctttc ggctttcttc aattcggtgc
    50401 tctcttttta atatgcgcca cgctgtcatg tatgtatcat gatcaatcaa acggctatca
    50461 tacagattac gcaattcgat agtcattaat tcaatgtcat agatgcgtgc acccacatag
    50521 ataaagatgc caaatttttt gaacagctgc tgtacatcat ataagctctc catctttaag
    50581 cacttccttc atattataca agtaaaccat atttttttaa acccagtaaa atacatatta
    50641 caaaaagaaa tacaaaaact agtgtagaaa gaatcctttg gtgtatcgaa tagcttgtct
    50701 gttgtttcgg tagacccaaa acattcccta acactaatcc gccaattagc ccaccgacat
    50761 gtccccaaac atctacagag gtatccagaa gaccaaaaac aaatgtcaac acaataaata
    50821 aaagaaaatg tctgactagc tgctggatcg ctgggttatg tttaaaatga aaccctaaga
    50881 taaacaacgc accgaacaaa ccgaatatcg aagtacttgc accaccagac agaacattcg
    50941 cttcgttaaa agcaaagctt gctgtatttc ccattatccc gctgaacata taaatcaaga
    51001 aaaaacgcca atggccatag attgcctcga tttgctgccc cataaaatac agtatcagtg
    51061 agttcattac gaaatgcatc agtccaaaat ggatgaagat tggtgtcact aaacgccacc
    51121 attcattgaa gtgaacaaga taaggaccat acattccggc ataataaggg atctcaagtc
    51181 gcggaaataa ttccatcatg aggaagaccg ctgtctgtat ccctaaaaaa gcataggtcc
    51241 ataacggtcg tcttaaccat gcacgcaatt ttatttgctg ttgataattc atgaaaacct
    51301 cccatttcat tttagtcaat aaacaattgt tggatcttct gatcaaagct ctccggttgc
    51361 cattgttcat tcaattgttc acgaaaaaca aggctacatg tttttttatg aaaattattt
    51421 aaataccggt cgtaataacc accgccaaaa ccgattcgat aaccggctct attgtagata
    51481 atacctggta caatgaggag atcgatcatc tccggcaaat agagcttctc tgattgtggc
    51541 tcaagaacac caaaactcga acgtacaaga acggactgtt catccatttc ataaaacgcc
    51601 atctgacgtt tcggcaaagt tttaggtaca actattttct tttgttcttt ttctgctcgt
    51661 tggataaccg gctgtgtatc cagttcaaat tcattcgata aagtcgtccc tatcactttt
    51721 gctgacttcc agtactcgct ggcgaatagc tgtttataga ttcgctgttc tttttccttt
    51781 ttcttgccac ttttggccag atttttcagc ttttcgattc ctttccggcg taatcttact
    51841 ttcaattggt ccaaaaactc acccttcctt ctctcataaa atggtatagg aaaaaaagaa
    51901 aaatagcaat cgaactttca aataaatgca taaatagaat aaaaagaaga cctagaaatg
    51961 attggccttc cttttttaat gaatttcaac tgttcagcgc gtgtttttgt ctgataaaaa
    52021 gtgcatacag aaaatatggc gcaccaaaaa gggcaatcaa aattcctgta ggtacttccc
    52081 cacttggtag aatcactcta gcaaccatat ctgcactaag cagaaaaatg gaaccgaaca
    52141 aaccgctcag aacaaaggtc cagttatttt ctttacgtac gactagcttc gcagcatgag
    52201 gagctagtag tcctacaaaa gataaactac ctgtcaccgc tacactaccg cttgccaaag
    52261 caacagctaa caacaaaagg attttttgac ttttagccac gttaaggcct aatccttgcg
    52321 cgcgttcttg accaaatgat agcaatacaa tcctctgtgc ataaagtcct cctagcggaa
    52381 ttaagataac cgcccatgga agcaatgccc aaacataagg ccagctcgca ccccagattg
    52441 atcccgctaa ccatgcattc acaaatccat aattttcctt agataattgg atcgtgcata
    52501 gcaatgttaa tgcagaaagg ccggcattaa cggcaatacc ggacaataag attcgattca
    52561 tacccaaaaa gccatttcga tcataggccg caagatagac acagcaagca gctaaaacac
    52621 cacctagaaa ggctacaact agcaatagaa acggcagcga atagtgcgaa aagaaaccta
    52681 aataaagcat cactaaaaat cctgctccgg cattaatgcc caatatacta gaatctgcca
    52741 attcatttct tgttactcct tgcaagatat aaccagaaac gccaagacaa gctcctgcta
    52801 ataaactgat cagtaatcga ggaactcgaa attctctaac aatcagcgcc aaagaagatg
    52861 attctttccc tatgaacgtg gcaaaaagct gatccaggta aataaaaggc gtaccaatca
    52921 ttaaactacc tatagacagg atgacaagta caaaaagcaa gaaatagaac gtccaatata
    52981 tttttttcac cgttgttccc tccttacttg tatcagtaaa aacggaacgc caatcaatgc
    53041 aatgactaat ccaaaaggtg tttcaaaagg gggattgatc atcctcgctg taaaatccgc
    53101 caacataacc aatccaccgc caactaaaaa agagacaggt agaacataac gatagtccgt
    53161 tccaaccatt ccgcgaacaa ctggcggaac caacagccca ataaatgaaa caggtccgac
    53221 taacgaaacg gcaatggctg ctaacactgc aactagacag aaaacaatca accgcgttcg
    53281 tttaggatga cttccaagag ctaatgcatg tgtttcactc aaatgaatca aagatattgc
    53341 ttttcctaat gaaaaagaaa ccaaaacagc aagtatatat aaaggaaaca atactgctaa
    53401 ttgtttccat gtgatattgg cagctccgcc tacaaaccaa aaagcaagat cctgctgcag
    53461 attaaagaat tgggtaagtg cttggctgat agcagtaaaa aaagaactaa tagctacgcc
    53521 agctaaaatc agctgtaaag gattcatgcc cattttcgaa aactgcaaaa aaccaaatac
    53581 gagcaaagtt acagcaaaag aacctgccaa tgacattaga aacacagaaa aatcagaagc
    53641 tttaggccaa aaagcaaaac taagggccat tgccaacgaa gcacccgcgt tgattcctag
    53701 taagcctgaa tctgctaaag gatttcttgt cactccttgc atcaatgcac cgctcaatgc
    53761 aaaacaactc cctacaagaa atgctcccgc cacacgaggc aaacgaatat ttcgtatgat
    53821 ttggtgactt tgttttgatc tatcaaaatc aaacaacgcc tgccaaaaat ctgctttttc
    53881 cacagtcgct gcgccatttg aaagagcaac aaaaaaaata atcaaaagaa caaaacagac
    53941 caaaagcagg agtctatttt tcttcatagt cctcataatt gatcctcctg ctcttttggc
    54001 aacaaatcat aggttagaaa aactggttta tttgttcttg gaagcgtgac aatcgttgca
    54061 tcaatctcaa atattttttt catacactct tttgtgatca cttcttcagg tgtaccttct
    54121 gtgatcaact taccgttttt cattgctaat aaataatctg aaaaacgtga agcatgatta
    54181 atgtcatgaa tcgacatcaa gatcgttgtt tgtttcattt gattgatttc agtcaataac
    54241 tgtaggatct ctaattggtg tgccggatct aaaaatgttg tcggttcatc caagatcaag
    54301 atatctgttt cctgagcaag cgccatagcg atccagacac gctgggtttg tccaccagac
    54361 agcgttgcga tatcccgcat acgaaatcca gctagacctg tagcatccaa cgcccactca
    54421 attgcttcat gatcttgcgt gtccatgcca ctgaacagtt tttgataagg gtatcgtccg
    54481 taagatacta cttcttctac tgtcatacct gtagggtgtt cactagtttg tgctaataat
    54541 gcaatttttt ttgcaagttc ttttgaactg tatgtagaga tatcagagtt attgacaatg
    54601 atctttcctg atttcacagg tagtatacgg gtaaaacttt tcaataaagt agattttcca
    54661 cttccatttg gcccaatcaa actagtgatt ttcccttcag gaatcgtaac agacatgttt
    54721 tcaatgattt ttttgttttc gtagccggct gcaatgtcag ctgctcttaa tctcgtcatt
    54781 tcacccatcc tttcgctgaa aatcattctc aattatgacg ctgtttcaac atttcgtcaa
    54841 gcgctacttt catatctata gccaaatgaa gcggttgaca gcgttcgaaa tatcaggaat
    54901 aataaccaat gagaaagatt ctcaattatg ttaggaggaa agaaatgaaa ttaaaaacaa
    54961 aagtattcac attatctagc atattgctgc tggctggagt actgagcgct tgctccccct
    55021 cttcagataa agaaacagct acaactgcca attcgacgac ttcatccaat agtactcata
    55081 cagtcacaga tacacttgga cataaagtag agattccaaa cgcgcccaaa cggatcatcg
    55141 gcagttactt agaagactat ctgattgcac taggggaaaa acctatcgcc cagtggactg
    55201 ttggcagtgg ttccattcaa gattatctgc aagatgattt aaaggatgtc ccaacgattt
    55261 cttatgacct tccttatgag aaagtgttaa gctttgagcc tgatttgctg ttgatttctt
    55321 cttccgctac tgtcgaaggc gggaaatacg aacaatatag caaaatcgcg ccaacttatg
    55381 ttgtaaaaaa cggaacagat gtcacatggg aagaacaact aaaagatgtc ggcaaagctt
    55441 tggcaaaaga aaaagaggca gaaaaaatca tttccgatta tcaaaaatcc atcaagaaaa
    55501 ctcgagaaga actagcagat aaaatcgaga acaagacagc tgcagtgttg tgggtgacca
    55561 acaactcagc ctttatggtc agcaaaaatc ggtcaagtgg aagaatcgta tacgacgatc
    55621 tggaatttgg tgttcctgat ctagtggaag aggtctccaa aaaagccact tctgactggt
    55681 ctgctgtttc ctctgaaaag ctagctgaat tagatgctga ctacatcatc cttgtgaaca
    55741 gtgacaaaga tgctgccatg ttcaatgaac caagctggaa gaatctaaaa gcagtgacag
    55801 acaatcatgt actgcaattc ggacctgaat ctagttggct atataacgga cctattgcca
    55861 gtcaggaaat ggtcaatgat atcaaagaaa aactaaattg attttaacta aaaaaagcat
    55921 cttcacgatt agtcgtgaga tgcttttttt cttattaaca aactagacgc atagatttta
    55981 ttcttctttt gaagcaaccc tattttttac tctttcccat ttttgaaaac gatgggcata
    56041 tagattttct tgatccgtta tcccctcata ctcctctata agggcgaagt ctgaaaaatc
    56101 aatattccca atatacgtat cgccttcaaa cgtgctatcg atcaatgttc gccagatccg
    56161 accagtgtaa ggaagaagtt cttgaaaaat ccgactacca cccgaaacat agatatcttc
    56221 tgagatcgtt tgactatacg acaaaagttc atcgatcgaa tgcattactt ccgcattttc
    56281 tttcgtgcga aaatttggtt gcgttgtcaa cacgatgata tggcgataag gaagtgaaag
    56341 atcccccatt ccttcatagg tctttcttcc catcactaaa attcgatcca ttgtatgttc
    56401 gcgaaagaaa cgcatatcat ttggcaatcg ccatggtaac aaaccatttt tgccgatcag
    56461 accattttta tcttgtgccc acatggaaat aaacatatta tccgctcctt atgattttag
    56521 atgttttgag ataaaaaaag tctcaattct ttgaccagca aggaattgag aactttaaaa
    56581 acattatttt gtttcacggt gcaaagtaac tttgcgttcg cgtgggcaat atttttgttt
    56641 ttccaaacga tcaggattgt tacgtttgtt tttgcttgtt agatagttac gttctttaca
    56701 agaagtacac tctaaagtga tgtttacgcg catgtttttc cctcccattt ttacaagaat
    56761 cctctaagat gactctcaga cttgattatc ttaccatgat tttttctaga ttgctagtgt
    56821 ttttcacgat tttgttaagt aaaactactt gacgataaat acaacggttt tacttctcaa
    56881 acaaaatctt tttctttttg tataaatacc cttacacttg tttatataga ttatgttttt
    56941 taataaaggg ggatactaat atgccatgga acatgaagga ctttcctgca tcaatgaaaa
    57001 acttagataa attgacaaga aaaaaagcaa tcgacatcgc aaatgcatta ttagatgaag
    57061 ggtaccctga taaccgtgcg atcccaattg ccattgatca agcaaaaaaa tggtatgaag
    57121 atgctagtga atcagaaaaa cgaactttcg aaaaagaaaa aaatccaagc aagacggatg
    57181 aacacgatac gaatcctcgt gctggaaaac tgcttgattc agatgtgatc gtagaatatg
    57241 aggaagaaca atggatcgtg aaatctaaag gggcaaaaaa ggcaagcaac cattttgata
    57301 caaaaaaaga agcaatcgaa aaaggaaagc aagtagcaca aaacaaagaa tcaactttgt
    57361 tcatttataa aaaagatggg acaaaagaaa aagaaatcga ttattgaaca tatgtaaagg
    57421 ggttgtgacg aaaatcgtgt cacaaccccc ttatgttcga aacaatggtg ttcctctgcc
    57481 aactccgaac cataagtcat aatatctata aaacgggaag agctgttttt tgaaattgtt
    57541 tcttatcact cagtgttaaa cggtaggaga aaacctcttt tttattgata tttgattttc
    57601 atcaaacagt cacatagtcg attgcttctg cttgcggaat cgtttcatct acaaagtaga
    57661 ctttatacca tgtcaagaaa ctgaagattg tccagatttt tctttgctct tctttacgtc
    57721 cttcgtgatg gtcatctagc aacttcatga ttttttcttg atcaaaaaat tcttttgcaa
    57781 aatctgcttc gaataatgct ttgacttgtt cgtagccgtg ttcttctttc aaccaagctt
    57841 tgattggcac agggaatcct aatttcacac gattcgacca ttcttccgga agatgtttgt
    57901 tcgcagcttg tctgaaaata tcttttgtgt tgttttgatt caataaaaac ttacttggta
    57961 tttgttgagc caatttcatg acttcgatat ccaataaagg tactcggact tccaaagaac
    58021 ttgccataga aagtttatct gcctttaaca agatatcttt tggcatccat tgatgaagat
    58081 cgacatattg catcttattg acttcatctt tgattccttc tgttttctcg taatgaacag
    58141 tcatgatttc atccacagat ggtgctgttt gatattttgg tgttaacact tctgatgctt
    58201 ctgattcttc gaacactcga gcatgaccga taaaatattc ttttgcagga gcaagtgatt
    58261 catataaatg gatccgtcca tggaagtttt tcatttttcc gattttacgt cctaaattat
    58321 agcgtgttcc ttttggtaat tttttcaatc cttgagcaat cacacggatg aattttgaat
    58381 tcgtatggaa tccatacgtt tggtatcccg caaacagttc atccgcccct tctccagatt
    58441 ggactacccg cacactttgt gaagcaagat ttgctaaaaa gtacaaaggt acgcaagaag
    58501 gatttgaatc aggttcatct aagtgatact ggatcaaagg gaatgctttg aacgacatgt
    58561 ctccgtcgat cactgctgct gtattatcta agtccaatag ttcggttagt tttctggctt
    58621 caatcgcttc attataggtt ttatcatcaa acccgattga gaaagaatga tctggtttca
    58681 atacagaggt tacataactg gaatcaaccc cgctggataa gaaagaacca acttctacat
    58741 cactgaccgt atgtgcttca atagaagctt gaacggtttc gtcgattttt tcgatccatt
    58801 cttgtcggga atgcgtttct tttgtttcaa aatctgcatc ccaatattgc tgaatgtcta
    58861 tttttccatc tttatacgta taataatggc cttcaggcaa acgatagaca tctttgaaga
    58921 atgtttcgcc gtttaatgga gaatattgga aagtcatata aggtttcaac gcttctttgt
    58981 tcaattcttt gttaaaatca ggatgaggca gaaaactttt gatttctgaa ccaaacataa
    59041 atgttccgtt catttctgca taataatatg gtttgatccc aaagtggtct cttgcaccga
    59101 ataactcatt cttttcatta tcccaaatag caaaagcaaa cattccgcgg atcttttgca
    59161 ataattctgt tccccattct tcgtaaccat gcaaaaggac ttctgtatct gcatgtgttt
    59221 gaaaaacgtg gccagctgca atcaattctt ctctcaaagg ctggtaatta tagatttcgc
    59281 cattaaaaat aatgatcttt gtccgatctt cattgtaaat aggctgagta ccgccctcta
    59341 agtcaataat acttaatctt ctgaatccta aagcaacatg tttatcgata tattctcctg
    59401 aactattagg tccacggtga acgattcgat ccatcattgt attaataatt gtttttttgt
    59461 tgtccttgtc gttaacaaaa cctacaatac cgcacattta actttcacat cctaatataa
    59521 aattactgtt tatttcattc atatgcatct tatcatagaa taaatagcgg acgaatattt
    59581 tctctcttac aatttcgtca cgtgaaaaca aaagatgaaa gtttctgttt ttacagaaaa
    59641 taaagtccca atatctaatt taccatgttt tcttttttga ggctacctta ttctcttcgt
    59701 gttaaaaaaa tattagtgga tgctatttcc aaaaaaacca gcaaaaaaag acacgaccta
    59761 aagatcgtgt c
//
LOCUS       DACBYO010000006        58707 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.006, whole genome shotgun sequence.
ACCESSION   DACBYO010000006 DACBYO010000000
VERSION     DACBYO010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 58707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.006"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            25..696
                     /locus_tag="IVD26_000339"
     CDS             25..696
                     /locus_tag="IVD26_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6078345.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="IVD26_000340"
     CDS             755..1195
                     /locus_tag="IVD26_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078346.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="IVD26_000341"
     CDS             1207..1875
                     /locus_tag="IVD26_000341"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP6078347.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1939..2562
                     /locus_tag="IVD26_000342"
     CDS             1939..2562
                     /locus_tag="IVD26_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAP6078348.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2618..3004
                     /locus_tag="IVD26_000343"
     CDS             2618..3004
                     /locus_tag="IVD26_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAP6078349.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3217..4608
                     /locus_tag="IVD26_000344"
     CDS             3217..4608
                     /locus_tag="IVD26_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAP6078350.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5219..5587
                     /locus_tag="IVD26_000345"
     CDS             5219..5587
                     /locus_tag="IVD26_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP6078351.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5767..6708
                     /locus_tag="IVD26_000346"
     CDS             5767..6708
                     /locus_tag="IVD26_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAP6078352.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6777..7508
                     /locus_tag="IVD26_000347"
     CDS             6777..7508
                     /locus_tag="IVD26_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAP6078353.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7652..9832
                     /locus_tag="IVD26_000348"
     CDS             7652..9832
                     /locus_tag="IVD26_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAP6078354.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9852..10334
                     /locus_tag="IVD26_000349"
     CDS             9852..10334
                     /locus_tag="IVD26_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAP6078355.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            10350..11111
                     /locus_tag="IVD26_000350"
     CDS             10350..11111
                     /locus_tag="IVD26_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAP6078356.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            11242..12576
                     /locus_tag="IVD26_000351"
     CDS             11242..12576
                     /locus_tag="IVD26_000351"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAP6078357.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12883..13368
                     /locus_tag="IVD26_000352"
     CDS             12883..13368
                     /locus_tag="IVD26_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAP6078358.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            13361..14044
                     /locus_tag="IVD26_000353"
     CDS             13361..14044
                     /locus_tag="IVD26_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAP6078359.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            14170..16815
                     /gene="polA"
                     /locus_tag="IVD26_000354"
     CDS             14170..16815
                     /gene="polA"
                     /locus_tag="IVD26_000354"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAP6078360.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16860..17696
                     /gene="mutM"
                     /locus_tag="IVD26_000355"
     CDS             16860..17696
                     /gene="mutM"
                     /locus_tag="IVD26_000355"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAP6078361.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17660..18289
                     /locus_tag="IVD26_000356"
     CDS             17660..18289
                     /locus_tag="IVD26_000356"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAP6078362.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            18341..18673
                     /locus_tag="IVD26_000357"
     CDS             18341..18673
                     /locus_tag="IVD26_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP6078363.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18985..19476
                     /gene="nrdR"
                     /locus_tag="IVD26_000358"
     CDS             18985..19476
                     /gene="nrdR"
                     /locus_tag="IVD26_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAP6078364.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19499..20872
                     /locus_tag="IVD26_000359"
     CDS             19499..20872
                     /locus_tag="IVD26_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAP6078365.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20872..21798
                     /gene="dnaI"
                     /locus_tag="IVD26_000360"
     CDS             20872..21798
                     /gene="dnaI"
                     /locus_tag="IVD26_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAP6078366.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21927..22367
                     /locus_tag="IVD26_000361"
     CDS             21927..22367
                     /locus_tag="IVD26_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP6078367.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22511..23212
                     /locus_tag="IVD26_000362"
     CDS             22511..23212
                     /locus_tag="IVD26_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAP6078368.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            23209..24330
                     /locus_tag="IVD26_000363"
     CDS             23209..24330
                     /locus_tag="IVD26_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAP6078369.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            24345..25577
                     /gene="pepT"
                     /locus_tag="IVD26_000364"
     CDS             24345..25577
                     /gene="pepT"
                     /locus_tag="IVD26_000364"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAP6078370.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25709..26617
                     /locus_tag="IVD26_000365"
     CDS             25709..26617
                     /locus_tag="IVD26_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAP6078371.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26652..26924
                     /locus_tag="IVD26_000366"
     CDS             26652..26924
                     /locus_tag="IVD26_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAP6078372.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            26935..27981
                     /locus_tag="IVD26_000367"
     CDS             26935..27981
                     /locus_tag="IVD26_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAP6078373.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            28232..30841
                     /gene="clpB"
                     /locus_tag="IVD26_000368"
     CDS             28232..30841
                     /gene="clpB"
                     /locus_tag="IVD26_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAP6078374.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(30992..31663)
                     /locus_tag="IVD26_000369"
     CDS             complement(30992..31663)
                     /locus_tag="IVD26_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078375.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(31656..32150)
                     /locus_tag="IVD26_000370"
     CDS             complement(31656..32150)
                     /locus_tag="IVD26_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAP6078376.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(32170..33390)
                     /locus_tag="IVD26_000371"
     CDS             complement(32170..33390)
                     /locus_tag="IVD26_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6078377.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            33537..35372
                     /gene="lepA"
                     /locus_tag="IVD26_000372"
     CDS             33537..35372
                     /gene="lepA"
                     /locus_tag="IVD26_000372"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAP6078378.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            35568..36479
                     /locus_tag="IVD26_000373"
     CDS             35568..36479
                     /locus_tag="IVD26_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6078379.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            37475..37726
                     /locus_tag="IVD26_000374"
     CDS             37475..37726
                     /locus_tag="IVD26_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078380.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            37809..38081
                     /locus_tag="IVD26_000375"
     CDS             37809..38081
                     /locus_tag="IVD26_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078381.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            38171..38410
                     /locus_tag="IVD26_000376"
     CDS             38171..38410
                     /locus_tag="IVD26_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078382.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            38557..42840
                     /locus_tag="IVD26_000377"
     CDS             38557..42840
                     /locus_tag="IVD26_000377"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HAP6078383.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            42939..43304
                     /locus_tag="IVD26_000378"
     CDS             42939..43304
                     /locus_tag="IVD26_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078384.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            43306..43758
                     /locus_tag="IVD26_000379"
     CDS             43306..43758
                     /locus_tag="IVD26_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078385.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            44372..45682
                     /locus_tag="IVD26_000380"
     CDS             44372..45682
                     /locus_tag="IVD26_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAP6078386.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            45705..46016
                     /locus_tag="IVD26_000381"
     CDS             45705..46016
                     /locus_tag="IVD26_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078387.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            46377..47633
                     /locus_tag="IVD26_000382"
     CDS             46377..47633
                     /locus_tag="IVD26_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP6078388.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            47630..48175
                     /locus_tag="IVD26_000383"
     CDS             47630..48175
                     /locus_tag="IVD26_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078389.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            48176..48676
                     /locus_tag="IVD26_000384"
     CDS             48176..48676
                     /locus_tag="IVD26_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078390.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            48757..49313
                     /locus_tag="IVD26_000385"
                     /pseudo
     CDS             48757..49313
                     /locus_tag="IVD26_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            49333..49677
                     /locus_tag="IVD26_000386"
     CDS             49333..49677
                     /locus_tag="IVD26_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078391.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            49696..50607
                     /locus_tag="IVD26_000387"
     CDS             49696..50607
                     /locus_tag="IVD26_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP6078392.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            50686..51678
                     /locus_tag="IVD26_000388"
     CDS             50686..51678
                     /locus_tag="IVD26_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6078393.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            51675..51893
                     /locus_tag="IVD26_000389"
     CDS             51675..51893
                     /locus_tag="IVD26_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078394.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            51906..52316
                     /locus_tag="IVD26_000390"
     CDS             51906..52316
                     /locus_tag="IVD26_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078395.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            52368..54896
                     /locus_tag="IVD26_000391"
     CDS             52368..54896
                     /locus_tag="IVD26_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP6078396.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            54912..57122
                     /locus_tag="IVD26_000392"
     CDS             54912..57122
                     /locus_tag="IVD26_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078397.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            57130..58221
                     /locus_tag="IVD26_000393"
     CDS             57130..58221
                     /locus_tag="IVD26_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAP6078398.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            58242..>58707
                     /locus_tag="IVD26_000394"
     CDS             58242..>58707
                     /locus_tag="IVD26_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078399.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFV"
BASE COUNT        19869 a         9664 c        12631 g        16543 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
     1981 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
     2041 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
     2101 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
     2161 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
     2221 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
     2281 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
     2341 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
     2401 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
     2461 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
     2521 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
     2581 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
     2641 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
     2701 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
     2761 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
     2821 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
     2881 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
     2941 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
     3001 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
     3061 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
     3121 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
     3181 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
     3241 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
     3301 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
     3361 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
     3421 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
     3481 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
     3541 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
     3601 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
     3661 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
     3721 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
     3781 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
     3841 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
     3901 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
     3961 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
     4021 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
     4081 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
     4141 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
     4201 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
     4261 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
     4321 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
     4381 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
     4441 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
     4501 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
     4561 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
     4621 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
     4681 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
     4741 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa tagttcctca
     4801 tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac cgtttaagaa
     4861 agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa aaaatagctt
     4921 ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa caccgtttac
     4981 cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca tataaataca
     5041 cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt atttattatt
     5101 aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat tttcccattt
     5161 tcctatggta aactgacaaa gttgagaatg ttagaacaga tcgtttagga ggaaacagat
     5221 gtttacgaat gaaataaaaa tcatgcttta tgtggacgat gtagaaaaaa atgcaacgtt
     5281 ttggagagca gttggctttg cggaaaaaga tcgtcaagaa atggatggga cgcttataat
     5341 tgaagtagga gttgaggaca gtcaaacctc atttctgtta tatgatcgag catttgttga
     5401 gtcccattca cctggcacag ctactagtgc cccatctttg atgttttaca gtaaagatat
     5461 ctttggacta tataaaaaaa tgcagacgca atcagtcaca ttaggtgata tggtacagct
     5521 tggagaagaa tatgtcttta actttgctga tcccgatggc aactactttg cggttacagg
     5581 taaataatag aaataaagac tttgtttttc tgtgcgaaac aggaaagcga agtcttttta
     5641 attcaaataa taatattatg taaacaaaaa actttccatg cgtaattata cacaagcaaa
     5701 taaatcgtca aatgcgaacg ccttctttat actgtttagg aacgaaaaga aggaaggaag
     5761 aaatacatgg attatcaagt actgctttat tacaattata caaaaatcga agaaccagag
     5821 gaatttgcca aaaatcattt agccttttgc aaatctttgg atcttaaagg tcgtattcta
     5881 gtagctgaag aaggaataaa tggtactgtg tctggaaccg ttgaaaacac gactgcctat
     5941 atgaaagcaa tgaaagctga tcctcgattt gctgatacga tgttcaagat cgatccaagc
     6001 gaaggacatg cctttaagaa gatgtttgta agataccgtc cagagcttgt aagtttaaag
     6061 ctagaagagg acattgatcc aaaccaagtg acaggtgcct atctttcacc gcaagaattt
     6121 aaagaagcta ttttagatga acagacagtg gtgattgatg cacggaatga ttatgaatat
     6181 gacttgggac attttcgagg ggctgtacgc ccagatatac gcagttttcg agagcttcca
     6241 gactggatcc gcgagcacaa agaagaattt atggaaaaac gggtagtgac ctactgtact
     6301 ggtggcattc gttgcgagaa gttttctggt tggcttgtcc gtgaaggatt caaagatgtc
     6361 ggacagctgc atggcggtat tgctacttat ggtaaggatc ctgaagtcca aggagaatta
     6421 tgggacggca agatgtatgt gtttgatgaa cggatcgctg tcgatatcaa ccaagtagat
     6481 aaacaaatcg tcggtcgcga ctggtttgac ggaacaccat gtgaacgata tatcaattgt
     6541 agcaatcctg agtgcaatcg tcagattctt gcttccattg aaaatgaaga aaaacattta
     6601 ggagcatgta gcatagagtg tgcgaaacat ccgcgcaatc gctatgttca agaccatgga
     6661 atctctccag aagaagcaga actgcggttt acagctttaa ttaaatagaa aacaatagtt
     6721 ttgattgtcg accatttcca atatgcgcta tactagcgtt gaggatggtg atccacatga
     6781 aatcattgat ttatgctatt ggggatgtcc atggcaaaca tgagcttttt gaaaaactta
     6841 ttcactatta tgatccaaag atccatcagc ttgttttatt aggggatctc aatgatcgag
     6901 gtcctcgtac aaaagaatgt tttttattag gaaagcaatt agtcgaagaa acaggagcca
     6961 tttacctccg gggaaaccat gaagaatatt ttttgcaatt tctgcaatca ccggaggact
     7021 ggtatgcgcc ttatatgaga aatggtggaa aagaaacgtt tgaaagcctg attcacccag
     7081 gggcatcgga ggaatactcc ccaactgaaa tctcgatgat gatccaatcg agatattcag
     7141 aactgattaa atttttagtc cagcgcccct tgtattatga atgggaaaat tatctttttg
     7201 tccatgccgg tgtggatttg acaaagaaag actggcgtaa gacaagtcta agagacttta
     7261 tttggataag ggaaccattt catgaaggga aaaacaatac aggtaagaca attgtatttg
     7321 gacatacgat tacaccaatg ctccatggag atatgcagac aacagacctc tggattcagg
     7381 atcataaaat cggaatggac ggtggggctg tattcggagg gtcattgcat ggggttgttt
     7441 ttgacaagga aggtattctt caagatattg aatatcagaa caacgaagga ccttggcatg
     7501 gaatctgact aatggaaaga atgaaggagc tgtgactttg ttgcggctct ttttattttt
     7561 atagagaata ttgtttcttt cagtagttta acccaggata aaaagtatga tagaataaag
     7621 aagcaatttt tagcagaaaa gaggcatttt aatgacggaa aatttgaacc agacgatcat
     7681 tcagcttgta caaaaagaac tttcagacta tcgtcctaag cagttgacta ctgtacttaa
     7741 tttgttaaat gaaggaaaca ctgttccttt tatcgcgcgt taccgaaaag aaatgactgg
     7801 aagtcttgat gaagtccaga ttcgtgaaat cgaagagcgg tatgcctatc ttgaaaactt
     7861 agaaaaacgt aaaactgaag tgattcggct aatcgatgaa caagggaaac tgactcccga
     7921 gttagaagca gaaatcaccc aagccgtgaa aatgcaacaa gtggaagatt tgtatcgtcc
     7981 atacaaacaa aaacgacgga caaaagcaac gattgctaaa gaaaaaggac ttgaaccact
     8041 cgcgaagtgg ctgatgcagc ttacagatgg agaggtgcaa tctgaagcag aaaaatatat
     8101 tgacaaagaa aaagaagtct cttctgccga agaagcgttg cacggtgctc atgagattat
     8161 tgctgaacaa gtcagcgata atgcaaaatt tcggacttgg attcggtctt atacgtataa
     8221 caaaggtatg tatgtcagca atgtcaagga tgagcaagca gatgaaaaag gcgtatatga
     8281 aatgtattat gactttgcag aacccgtcca taaaatggtt tctcatcgaa tattagctac
     8341 taatcgtgga gaaaaagaag atattctgaa agtattcttt caagtagatg aagcagcaat
     8401 tttagcttac ttggatcgcc aaatagtcaa aaatcctgcc tctccttctt cttcattcgt
     8461 cagagaagcc tatcaggata gttataaacg ctttattcag ccagcaatcg agcgagaact
     8521 gcgcaatgaa ttgactgaaa aggcagatga gcaagcaatc gctattttcg gcgaaaacct
     8581 ccgtaatctt ttgttgcaac cgccactaaa aggtaaagtt gtcctgggat ttgatccggc
     8641 ttatcgtact ggatgtaaac tagcagtcgt agatgcgaca gggaaagttt tagcaatcga
     8701 agttatttat cctcataaac ctgcagcgca agcaaaaaga gaagctgctg gaccagcttt
     8761 tatccaatta attaataaat atcaagtaga tatggtagct atcggaaatg gtacagccag
     8821 tcgggaatct gaactttttg tggctgagca gttgaaatcc gccgaccata aaacctatta
     8881 cgctatcgtc aacgaagcag gcgcttctgt ttactccgct agcgaaattg cacgaaaaga
     8941 atttccgcat ctacaagttg aagaaagaag tgctgtttct attgcccgtc gcctgcaaga
     9001 tcctttagct gaattagtca aaatcgatcc taaagctgtc ggagtaggcc agtaccaaca
     9061 tgacgtttct caaaaacgtt tggctgaaca attggatttt gttgtggaaa cagcggttaa
     9121 ccaagtaggt gtggatgtga atacagcaag cccgcagctc ttgcagcata tatcaggatt
     9181 gaataaaaca actgcccaaa acattgtcat ttatcgtgaa gaaaacggag aattcaccgc
     9241 acgaactcaa ttgaaaaaag tgccacgctt aggaccaaaa gcatatgaac aagcaatcgg
     9301 attcttgcga gtccctggtg ggaaaaacat tttggacaac acaggtatcc atcccgaaag
     9361 ttattctatt gcaaaagaaa tattaacttc agtccaactt tcagaaaaag agcttggtac
     9421 agaagaagca gtagaaaaat tgacacgatt atccgtagag aaactggctg aaagcctatc
     9481 agtcggagaa gaaacgttag ccgatatttt agctgggctg acacaacctg gacgagatat
     9541 gcgtgatgag atgccagcgc ccttattacg tacagatgta ttgagtatgg aagacttgaa
     9601 accagggatg gaattgactg gaacggtccg taatgtcatt gacttcggcg catttgttga
     9661 tatcggtgtg aagcaagacg gacttgtcca tatatcgaaa ctcagcaaaa aattcgtcaa
     9721 gcatcctaca gatgtcgtgt cagtaggaga tatcgtaaca gtttggatag aacaagtcga
     9781 tacgaaaaaa ggcagaatca gtttgacgat gctttcccct tatgaagagt aacaatgagg
     9841 agtaacaaaa attgacacaa gaagaactgc agcagttagt agaagagata tcattaaaaa
     9901 gcttccagct tcctttcaag caccaagcaa tgttcaatcc acgcttacgt acaactggcg
     9961 ggcgctatca tttaaacgat catcatttag attttaatgc gaagctattt gaagagtcag
    10021 acgaagagac gattgcagga atcatcaaac atgaactttg ccattatcat cttcatctag
    10081 ctggaagagg gtatcagcat aaagatatgg atttcaagta tcttttgaaa aaaacaggag
    10141 ggttgcgcta tgcaccagcc ttgacgaaga aacagataaa gatggagtat tatcgatgcc
    10201 aagattgttc tgccacgatc tgccgcaaga gaagaatcga tgtacgcaaa tatcgttgtg
    10261 gaagatgtca tggagaaatc aaatggattg agacaaaaag agaagacttt aatgaagcac
    10321 aaaaaatcag atgaaaggat agaaggcctt tggaaaaaag tgagcagagg aatctaaaag
    10381 actggaatca gctattaaat tttttagccg cacctgaaga gggaaatttt gaggaactga
    10441 cggcacctac acttatttta gctggaaact gtcttcctat cttagctgat aaagcagcac
    10501 aaatgtattt aaatggccaa gtagatcaat tgtttttggt cggaggggtg gggcatgcga
    10561 ctagaatcct ttatgagaat tttgaaaagc aaggatttca ttttgaagat ggcatgagtg
    10621 aaagtgaaat ctgtcgtcag tatctaaaag aagtctatga tttgcccgat aaggcttttc
    10681 tgatagaatc gaagtctaca aattctggag agaacgccac tttttcactg gagattcttc
    10741 attccttagg agctgtacca gaaaaaatct tattgatgaa tgatccgaca ctgcaacgca
    10801 ggactcgagc aacttttgag aaagtatggc aaaatgaaca aactattttc gcgaatgctg
    10861 tgccatttgt gccggaaatc cttcactttt ctgaagagat catctttaca gcaaaagaac
    10921 tgaatcatca atggcctaag gaatatttcc atgcgctagt attaggagaa atggaacgtc
    10981 tccatgacga tgagaacggc tatggtccga aaggaaaaga ttttattcct cacattgata
    11041 tatcagagga agtttggtct tcttacacca gaattaaaga gtcaataaaa acggattttt
    11101 ctcgtacttg accattttag caagcgaatc ctcctttcca aataaatttg gttgaaattt
    11161 tcaatcgttt ataagataat gaggagcgtg ttgaatgtaa tagctaaaag aatggacgct
    11221 agataagaga agaggattca aatggaaaat caaaataaat tgtatcattt tgttggtatc
    11281 aaaggttcag gaatgagctc cttggctctt gttttacatg aacaaggtct aaatgtccaa
    11341 ggatcagaca ttgaaaaata tttctttaca caaagagatt tagaaaaagc aaatatcacg
    11401 attctgccat ttaacgcaga taatgtaaaa ccagggatga cgatcattgc aggaaatgca
    11461 tttcctgatt cacatgaaga aatccagcga gcaaaagaat taggtttgga agtgattcgc
    11521 tatcacgact ttattggtca ttttatccaa aattatacga gtatcgctgt aacaggctct
    11581 cacggaaaaa caagtacgac tggactgctc tctcatgtat tgagtggtgt ccgtccaaca
    11641 agttatctaa ttggagatgg aacaggacat ggtgatccgc aagcggaatt cttttcattt
    11701 gaggcctgtg aatatcgccg tcatttcctt gcctattcac cagactatgc aatcatgacc
    11761 aatatcgatt ttgatcatcc ggattattat acaagtatcg acgatgtatt tacagctttc
    11821 caaacaatgg ctggacaagt gaaaaaagct atttttgcgt atggtgacga tgcttattta
    11881 cgcaaattaa aagcaaatgt gccgatttat tattatggtg tcacagaaaa cgatgatatc
    11941 caagcacgaa acatcgaacg cacaacttct ggttctgctt ttgatgtcta tcatggggat
    12001 gaatttgttg ggcacttcac tgtaccagca ttcggtaaac acaatatctt aaatgcttta
    12061 ggtgttattg cagtagctta tttcgaaaaa ctggatctga aagaagttgc agaagaaatg
    12121 ctgactttcc caggagtaaa acgtcgattc agtgaaaaga tcgtagcaga catgaccgta
    12181 gtcgatgatt atgcgcatca ccctgcagag atcaaagcaa cgattgatgg cgcacgccaa
    12241 aaatatccag ataaagaaat aattgcagtt ttccaacccc atacgtttac gcgtacgatt
    12301 gcattgatgg atgaatttgc agaagcactt gatttagctg ataaagttta cttatgcgat
    12361 atttttggtt cggctcggga agaacaagga aacgttaaga ttgaagacct tggagcgaaa
    12421 atcaaaaaag gtggagaagt catcaaagaa aataatgtat ctccattgtt agattatcat
    12481 gatgcagtag taatcttcat gggtgctgga gatgttcaaa aatttgaaca agcgtatgaa
    12541 aaacttttaa gcagcacgac gaaaaatgta ctgtaataca attactgcag tgtccttata
    12601 aaaatagaaa gagggggagt ggcaaaaatc ttgccaagcc cccttttttg caacttatga
    12661 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aatcaaatca aaaacatgag
    12721 aagctgtttt ttcttggctg ttcttattat ttgatgcagg acagcttttt cacgacctct
    12781 gtaaactata ggaatctgtt aaatcaaggg agcagaactt gccttttacg ctacttttgg
    12841 tacaataatg tatgattaaa aataaactgg agggtttcta tcttgaacat aggtaagccg
    12901 agaaaactag gaaaaacaat aaatgaaatc gaggaaggcg actcgttatc cttaacagaa
    12961 tctattgaag ataaccagct tttgctgtat ttgggattga cgaatgatgc aaatcctttg
    13021 tatatccaac atgactttgc acaaaaaaca gaatatcaac agccaatcgt tccatcagtg
    13081 atgctgatgg ggatcatcac aagtgcaatt tcaaagcatc ttcctggacc aggatcacat
    13141 gttgtcaatt tttctgtcaa ttttattgaa ccggttttcc attatgaaac actgactttt
    13201 cagtttgagg tcataaaagt agataagatg aaggatgtgg tgacgatttc tgtagaagcg
    13261 gagaatacga acgaagatcg tgtgttggat gctgtcgtta tggtccaacc gccacaagtt
    13321 cctgaattgg aaatagcaat cgaaagtgaa ggtgaattga atgaataatc caagtacatc
    13381 aatgtcaggt atcaatcgtt tttatgcaaa agtttatgga tttttaggta tgggacttgc
    13441 ccttagtgca gtcacttctt acttggctct ttgggtattt cctttgcaat tagcaacttt
    13501 tatcaataat tttccactag gctttgtggg tctgtggatc gttgaactga ttttagtaat
    13561 ggttctaggc gtaaaagcac aaaagaatcc gagcttagca atcggtggat ttattgccta
    13621 ctctcttttg aatggcataa tattagcggt tactcttgca tactacgata ttggaacagt
    13681 aacgcaagct ttcttgacag ctactttgat gttcatgggg atgtctgttg tcggagtaac
    13741 aacaaaaaga gatcttagcg gggttggaag agcaggacag gcagctttaa tcggagtgat
    13801 cattgcacta gtcttgaaca tcttcatttt gagaagtagc gtagttgagc tgttcatctc
    13861 cctactgtta gtcgtcatct ttgcagggat tacagcttat gataaccaaa gcatccgtaa
    13921 tatctatgtc cagacaaacg gaacagcaca tagtggaatt gctgtattca tggcattgaa
    13981 gctgtatttg gactttatca acttgttctt ggcgtttctg agaatctttg gacggaacaa
    14041 ctaaaaaaga aaaaaattca tcagttgggg ctataccgaa ttatttggta tggtcccgct
    14101 ttttcttttc gcattccgca ggattctttg ttagaatgaa taagaacttt acagtaagga
    14161 gttaagaaga tgacaaaaaa taaattatta ctcgttgatg ggaacagtgt ggcttttcgc
    14221 gcattctttg cgcttcacaa ttctcttgaa cgtttcaaaa atagaaacgg tcttcataca
    14281 aatgcaatct atgcattcaa tacgatgttt gaaaatgtta tgcaaaaaga gcaaccgact
    14341 catgttctgg ttgcgttcga tgcaggaaaa acgacttttc ggacagaaat gtatgcggag
    14401 tacaaaggtg gaagatccaa aacacctggc gaattcaaag aacaaatgcc atatatacgt
    14461 gatttgttga caggactagg ggtacagtat tacgaattgc ccaattatga agcagatgat
    14521 attatcggta ctttggcaga aaaagtagac aaagatcaat ttgatgtcgt cgtgctttca
    14581 ggtgatcggg atttgactca attagctagt aaagaagtaa aagtggatat cactgtaaaa
    14641 ggtgtcagcg atatcgaaag ctatacacca gaacatgtag cggaaaaata tgatgggttg
    14701 acgccaaaac agattattga catgaaggga ctagccggag atgcctctga caatatcccc
    14761 ggtgtgacta aaatcggtga aaaaacagct atcaagctat tgaaacaata tggctcagtc
    14821 gaaggaattt atgaacatat cgatgaaatg aagcaaagca aaatgaaaga aaatctgata
    14881 aatgacaaag agcaggcttt cttatcgaaa aaattggcga ccatcaatac ttcagcgcct
    14941 gtggatgtct ctatcgactc attgaagtat gaagggaaaa atctcgataa actcgttccg
    15001 ttttataaag aaatggattt caatcagttc ctttctaaat tgaatatcgt agaagaagaa
    15061 gtaaaaatgg atgatatttt gtttgaagtc gttcatgaat tcaaagagga aatgtttact
    15121 acggatatgg cgttgtacgt ggaaatgatg ggcgacaatt atcatacaga ggaaatcgtc
    15181 ggagtagcgt gggggacaga aaagaaaatt tatgtcacga acgatctatc tgtattcgaa
    15241 aaccgagcgt tccattcttg gatcactgat ccgactcggc tgaaaaaagt atatgatgcg
    15301 aaacgaactt atgttgcttt aaaccgctat actggaaaaa cgaaaggaat cgattttgat
    15361 gtcttgctag gtgcatacct tctcgatacg aatgaaaaaa gcacagatat cgaaggaata
    15421 gctgctcatt acggatacaa cgatatccaa tcagatgaag ctgtatacgg caaaggggcg
    15481 aaaaaaggtt taccagaaga agaggaactc ttttttgctc atttagcgcg aaaagtagct
    15541 gcaatcaatg cgttgacacc aaaattgagc caagaactgg cagaaaaaaa ccaagaagat
    15601 cttttccgga aaatggaact gccattgtct atcattttgg cagagatgga aataagcggg
    15661 atcaaagtag atgcgactcg cttacaagaa atgaagggcg agttctctgc tcgcttaaga
    15721 gagatcgaac aaaaaatcta cgaagaagcc ggcgaagaat tcaatttgaa ttcaccaaag
    15781 caattaggag tgatcttatt tgaaaaaatg ggattacccg ttatcaaaaa aacaaaaact
    15841 ggatattcca cagccgtaga tgtactggaa cagcttcgtg aacaagcacc aatcgtagag
    15901 gatatcctca cctatcgtca aattgcaaaa attcaatcta cctatgtcga gggactgctg
    15961 aaagtgatcc aatcagatgg aaaagtgcat acccgttatg tccagacatt gacccaaaca
    16021 ggacgattaa gctctgttga tcctaatttg cagaacatcc cgattcgatt agatgaaggg
    16081 agaaagatac gtcaggcatt tgttcctaga gaaaaagact ggctgattta ttcttctgac
    16141 tattcacaaa tcgagttacg cgtacttgcg catatctcaa atgatgaaca tttgaaagct
    16201 gccttcctag aaggtcaaga tatccatgcc agcacagcga tgcgtgtatt tggaatcgaa
    16261 aaggcagagg atgtcacacc aaatatgcgt aggcaggcaa aagcagtgaa ttttggtatc
    16321 gtgtatggca tctctgatta cggactttca caaaatctag gaatcagccg aaaagcagca
    16381 cagcaataca tcgatacgta ctttgaaaaa tacccaggtg tcaaagaata tatggaaaga
    16441 atcgtacgcg aagcaaaaga ccaaggctac gtcgaaacgc tgtatcaccg ccgtcgatat
    16501 ctgccagaca tcaattcaag aaattacaat atccgttctt ttgcggaacg aacagctatc
    16561 aatacaccaa tccaaggaag tgctgctgat attttgaaaa tcgcgatgat cgaattggat
    16621 aaacgattaa aagaaacagg tcttcaagct acgatgctgt tacaagttca tgatgaactt
    16681 gtcttcgagg taccggaaaa agaacttgaa tcattagata aattggtgaa ggaagttatg
    16741 gaacaagctg tttctcttca tgtaccactg atcactgaca gcagttgggg aaaaacgtgg
    16801 tacgaagcaa aataaacatt gtttaagaca gagcaatata atgaaggtga aaagaaaaaa
    16861 tgccagaatt accagaagta gaaaccgttc gtaaaggatt ggaacggtta gtagtaggaa
    16921 aaacgattca aaaagttcag gtcttgtggc ccaagatcat cgagcaacca gagacaccca
    16981 tctttgaggc ttctcttgtt ggcgaaacca tccaatccat tggacgtaga gggaagtttt
    17041 taatttttca tctcgatcat tgtgaactga tctcacactt gcgaatggaa ggaaaatatc
    17101 aatttacgaa agaaaataca ccaatcgata aacatacgca tgtacttttc ttttttgagg
    17161 atggaagcca acttcgctac aacgatgtac gaaaatttgg tcgtatgaca atcgtcgaaa
    17221 aaggagcaag tgcaacttac cgaggaatca tgaaattggg acctgagcct ttgccagata
    17281 gcttcttatt agcagatttc gcaaatggac tgaaaaagtc ccacaaagca atcaagccat
    17341 tgctgctaga ccaacgtcta gtgactggtc taggtaatat ttatgtagat gaagcattat
    17401 gggaagcgaa gatccatcca gaacaaccgg cgaacacact gcgccccaaa gaggtagaac
    17461 aattacgtct atcgatcatt gatgttttgg atcgtgcaat agaagccgga ggtaccacga
    17521 ttcgcagtta tttgaatgca ttaggagaat caggcggatt tcaagtagca ctgcatgtct
    17581 atcagcaaac tggcaaacca tgtatacgtt gtggaacgcc gatcgtgaaa acaaaagtgg
    17641 cacaaagggg gacgcactat tgtccgaatt gtcaaaggct aaaaatcgca aagtaggatt
    17701 tgttttaggt ttgacgggtg gaatagctac cggtaaaagt acggcagcca aagtctttca
    17761 gtctcatgga tttcctttga tcgatggcga tgtgattgcc agagaaactg ttgagcctgg
    17821 aacgcttgct ctgaggaaaa ttgtatcagt gtttggccaa gaggtattgc agcctgatgg
    17881 gcaactagat cgagggaaac ttgggatgat tgtttttcca tcaaaggaaa aacggcaaaa
    17941 acttgatcag ctattagatc cgtttatccg aaaagcgata aaagatcaaa tcgcctctct
    18001 aagttccaat catcctttag taattgtaga tatcccattg ctctacgaag gtcattatga
    18061 ccactatatg gatgcagtag ctgtcgttta tactacgcca gaaactcagc ttcagcgttt
    18121 gatgaaacgt aatcaactga cgctagaaca agcgcagcag agaattagta gtcaacttcc
    18181 aatcgaagaa aaaaagcagc gtgcggatat tttgttcgac aacaatggaa caaaagaaat
    18241 acttgtggga caaatcgaaa attggctttt tgctaatcgc tttctttgag tatctgtgtc
    18301 aattttgcta tcctgagtat atagaaagtg agggatagcg atgggatcat taaaaaatca
    18361 aaaggataaa gtcgtaggta acgcaaaaga aaaaatcggc gagatgctca ataaagaaaa
    18421 tctaatcgat gaaggtcgta cgcaatcaga aacagcagaa gaaaaagaaa agcagtacca
    18481 agcaagaatc gatgaaatag aagaccagca ggcagaagaa gaagcgaagc ggcaagattt
    18541 gactcaagaa cgaaaaaatc cgacacctga tcgtagtaaa acaccgctcc cagaaagtga
    18601 ccacattccc gatgagcaaa aaatcgagga acagcgaatg aaacactata caggaatcga
    18661 agagaagtta taaaatagta aaaaatcgag atgtgacttg aagcagatga gaaggtgttc
    18721 atctgcttca agttttttgt gctagatgac taaatcagct tttgtgtaag ttatttctca
    18781 gtaatcaagg tgatcagtat tggaaaattg aaatttagta aggacagggg acacaattac
    18841 gcatgaaagt agaaaaaatt gttcttatat ccgtgttttt tgggtaggac agtcgcgttt
    18901 gtgatttgtt tcgtgttata atacaactag ttgtaaagaa agacacatcc tttatataaa
    18961 atgcgatgca agaggtgaga caaaatgaga tgtcccagat gtcaacataa taattcacga
    19021 gtaatcgaca gccgtcaagc agatgatgga cgtgcgatcc gtcgccgtcg cgaatgtgag
    19081 aattgttcgt tccgattcac tacatttgaa cgaattgaag ctgctccgtt attagtaatc
    19141 aagaaaaacg gggaacgcga agagttcaat cgcgataaaa ttttaagagg actcatccgt
    19201 tcagcagaaa aaagacctgt agctatggaa caaatggaac aaatcgtcaa ccatgtcgaa
    19261 aaccgcgtac gcagtctcgg agaaaacgaa gtatcgacga atctaattgg tgaatatgtg
    19321 atggaagatt tagttgattt agacgaaatc gcttatattc gttttgcaag tgtttatcgc
    19381 cagttcaaag atatgtctgt tttcttaaaa gagttgcaag atatcgtgga taaagcaaaa
    19441 gaaaataata aagagaataa taaagaaaac aattaagaaa caaaaaggag gcatttcctt
    19501 ggaaaatgct tggaaagagc ttcaaccaaa aaatatttac caaggaagaa aagcggctcc
    19561 gctgagagaa gacagcaaga acgccttgct gtatctttat cagccactaa tcggcggaga
    19621 agccttgagt atctatttca ccctgttatc agaaatctct caagaatctg gcaaaggtcc
    19681 tgaagggatg catgcagatc tgcttagtag tctaggctgc ggtatcccgc aattttatga
    19741 tgcaagaaaa aagctagaag gaatcggctt actggatgtt tattttaaag aagatagtga
    19801 tctgggacct cgttttattt atgagctgtt agaaccactc attcctaaag catttttcaa
    19861 agactctgtt ctggcttttc ttcttctgga aaaagttggt gaacgacgat tccagaagct
    19921 tacccaattc tttgaaccta aaaggcatac agcagaggga tatcaaaaaa tcacaaaaaa
    19981 atttttagat gtttatcgct tcaatgaagc agtgtacgct gctaatcaag aaaacatcga
    20041 atcgctgaat aaatcttttg aagaatctga atcagtagca ttacttgaag cagattcgac
    20101 attcgattgg cagtttttga atgattggct ggcaaaaaaa catattgcaa gtcttgatga
    20161 tccaatcatc aaacaagtcg acatgtatca tcagctttac ggtttcgatg aattgacact
    20221 tggcgaactg atcagtcaat cttatgactt tagtgaacaa aaagtatctg aaaaagaact
    20281 gcaaaaagcc attttggcaa tgcagagacg tccggtgaag caaacaaaag aaacagttgc
    20341 ggtttctgaa aacagtaatg aaccctcgtc aaacgaacat ttgacaaacg cagcgcttca
    20401 gctgataaaa gaagcacaga gcattccacc gatgaaatat ctggaagcaa tcaagtcaga
    20461 aaaaggcgga tatgtttcta aacaagaaaa ctggttactg caagatcttg tttctcaatc
    20521 aggtctttcc agtagcgtga tcaatgtttt gctgaattat gtactagtga tcaagaataa
    20581 tgctagctta aatgccagtt atgtaaatac agtggcaaat gaatgggcac aaaagaaaat
    20641 cgccacagca gaagaagcga tccagcacat tcggcaaata agtaatcaag caaaacaatc
    20701 aaaacaaaag aagcaaacaa attatcaaac tggcaagcga aatgttcgac gggaaaagct
    20761 tcctgattgg gtcaaccagc caaaagatga aaaacagatc agcagcgaga aaaaagcaga
    20821 gattgaccgc cgttttaaag aatacctggc aaaaaaggag ggtgatatct agtggaagac
    20881 gtaggcaaag aattgaagag gatcatcagc aaacgcaatt atcaagaaaa gtatgctgaa
    20941 atgatcgctg aagtcttaaa tgatgcggat gttcaagctt ttctaagcgc acaccaagaa
    21001 gaattgacac aagcggatat tgaaaaaagt tacgctaaat tgtatgaatt cgtgcaagaa
    21061 aagcgtaaat atcaaaaaaa cgatccaacg atgatcgctc ccggctatga gccgaagctg
    21121 acgttgaatt ttcattatgt ggatgtcact tatgtaccaa cggaagcatt gttagcacgg
    21181 caaagacaag aagaaatcag aagccgagta aaagcaatgg atatgccaaa agatattcaa
    21241 tcggcttctt ttgaaaactt tgaacgtaca gatggacgag gatatgcgag cttagaagcc
    21301 ctagattttg tagagaaata tactgctgat ccaaaagggt atcataaagg actgtatcta
    21361 gtaggaagtt ttggtattgg aaaaacatat ttattaggag caacagcgag agaattagcg
    21421 attgctggat tcaccacgac gctagtccat tttccgacat ttgccgttga gatgaaacag
    21481 gcaatcggaa aagatcaagt ggcagaaaag ttagatgcag tgaaacgttc acctattttg
    21541 atgatcgatg acattggtgc agatgcgatg agtagttgga tacgagacga agtattcggt
    21601 gttatccttc aatatcggat gcaggaacag ttaccaacct tcttctcatc gaattttaca
    21661 atggatgaat tggaacagca tttgtccgtc actcaacgtg gagatgaaga gccgctaaaa
    21721 gcgaaacgga taatggaacg catacgttat ttgacaaaag aaatcgaaat gactggtcgc
    21781 aaccgacgca atggttgaac agttgacaag tccaactgac atttgaccta gtagtaaaag
    21841 caggtcagcg aatcattata tggacagaaa tgaccggaga caatcaccgc aacaagtaat
    21901 gcagaaactt aaacggagga ttttttatga gggctatttt ttctagtata tctgtagttg
    21961 gtctattttt tcttttagca ggctgcggta gcgcagatag caacacaggt tctgttgatt
    22021 cgattgatgc gggtcaaaca gtaaaaacaa gcagtacgaa aacggagaga caaagcatat
    22081 ttgtcggaac gattgaaagt atcactcaag tagaagcaga agaagaaacg cttcagttga
    22141 aactcgtcga tgtcatggcc aaagaagatc cagcgaatat gggaacgtca ttcagcaatg
    22201 acggagtgat cttaaatgct actgctgaaa aaataagcgt ggacataaat gaattgaaaa
    22261 tcggtgacaa agtccaattt acattagttg agatgccgat catgacgatg tctatcccac
    22321 cgcaagttcc tggagattcg attattgatg tttcattgaa caaataacca ataacatttt
    22381 ttcaaaaata agaaaatgtt gttttataga acgaaaaggt atatttttta aggagatatg
    22441 ggaatttttt tattcctagt ctccttattt tatttggaaa atgctataat tatctagaag
    22501 gagtgaagct atgaaccatt tagatttatc tcagcgctta gccgcagtgg gtgactttgt
    22561 ccctgaatcc gctcgtttag cagacattgg atcagatcac gcttacttac ccgttgcatt
    22621 gatattaaga ggaaaaatcg aatatgcagt tgctggtgaa gtcgttcaag gtccttatga
    22681 atcagcacgt aagcaagtca aaaaagatgg attagaagac cgtatcaccg tacgccttgc
    22741 aaatggtcta gatgctatcc agccacaaga tggtattaca gctgtcacga ttgcgggtat
    22801 gggaggttca ctgatccgag atatcctaga agctggcaag ttgaatcaac gcttaagcgg
    22861 acaagaacgt ttgatccttc agccaaacat cggagagcgt acattacgat cttggctgca
    22921 agaaaatcag tataaaatcc aatcagaaaa aatacttgaa gaaaataaaa aaatatatga
    22981 aatcattgta gccgaaaaag aacaaaaacc agttacttac aatgaaatgg agctgatgtt
    23041 cgggccattt ctgcttgaag agaaaagtga gatcttcaaa tcaaaatgga caagagagct
    23101 tcaacaaaga aaagctatcc gtgaacagct caaacaagca gctaatcaag aggcacgtca
    23161 aaaacaaatc gagcaggaaa tccaaatgat tgaggaggtt ttaaagccat gacaatcagc
    23221 ggacgcactt tcatccaaaa gtttgaaagc tattgtcctc agtggctagc tgaagaagga
    23281 gacccagtcg gactgcatat cggaacattg gataagccaa tccaacgagt aatgatgaca
    23341 ttagacgttc gtccagaagt ggtcgaagaa gcaatcaaga aaaaaatcga tttgctgatt
    23401 gctaaacatc ctccaatctt tcgtcctgta aaacggctgg ttactgatca gccacaagaa
    23461 aaaatgtatg cagatttgtt gaaacatgat attgccgtct atgcagcaca cacgaacatg
    23521 gatattattt gggatggact gaatgactgg ttttgtgaac ttctcggtat tgaagtggag
    23581 agttatttag taaagactca tgagattcat tataaaaaac tggccgttta tgtacctgtg
    23641 gatcatgcac agaaaatgcg tgaagtatta gctgcagctg gtgctggtac acaaggtgat
    23701 tataccggta caagttttac ctcgattgga cacggtcgat ttactccgga agctggtgca
    23761 caaccagcga ttgggaaagt agggaagaca gaacaagttc aagaggcaaa agttgaggtt
    23821 attttgccgg aaactatcga aaaacaagtg attcaagcca tgcggtcagc tcatccttat
    23881 gaggaacctg cttatgatct tttcgctata gatgaaccag tcgaaatgtt tgggttagga
    23941 cgagtaggtg aattgccgca agaaatttct atagaggcat ttgtagaaca agtaaaagaa
    24001 gcgttccaac tagatggact gagaatagtc cagccaaaaa atgcaaaatc ctctgtgaag
    24061 cgcattgcga tttgcggtgg aagcggtgaa aaattttatc cgcaagcaat cgcccaaaga
    24121 gcagatgtct atatcacggg agatatctat tatcatacgg ctcatgatat gcaaagcgct
    24181 gggttgattg caattgatcc cggtcattat attgaatcgt tatgcaagca acgatttatc
    24241 gagaaatttg aatcttggaa acaagaagaa aattgggata ttaacttttt cgtttctgaa
    24301 acaaatacaa acccatttca atttaattaa aaggagagaa tactatgtac gaaaatcttt
    24361 tgccacgttt tttacgatat gtcaaaacag aaacacgctc cgatgcaaca agcaaaacga
    24421 ctccatcgac tcagacacaa gttgcttttg cgcaagaatt gaaaaaagaa ttagaagagt
    24481 taggcttagc tgatgttttc tataatgaag ataacggatt cgttatggga acattaccaa
    24541 gcaatgttga tcatgaagtg cgttccattg gatttatttc ccacatggat acagcagatt
    24601 ttaatgcagt aggagtcaat ccacaaatca ttgaaaacta tgatggcgag tctacgatcg
    24661 tactagatgc ggaagaacgc tatacattga atacaaaaga ttttccaaat ttgaaaaatt
    24721 atgaaggcca cacattgatc acaacagatg gcagtacatt actgggagca gatgacaaat
    24781 cagggattgc ggaaatcatg actgcaatgg agatcttgat caataatcct tctatccctc
    24841 acggtaccat caaagtggct tttggtcctg atgaagaaat cggtgtcgga gcggataaat
    24901 tcgatgttga gcaattcgat gtagattttg cttatacagt cgatggtggt cctttaggtg
    24961 agttgcagta tgaaacgttt agtgctgctc aagcaaatat tacgatccaa gggaaaaatg
    25021 tacatccagg gacggcaaaa gatacaatga tcaatgctct acagttagca atcgattttc
    25081 ataatcagct tccagccgat gaagttccag aaaaaacgga aggatacgaa ggtttcttcc
    25141 atttgatggc attggatggg aatcctgaag aagcttctat gagttatatc attcgcgatc
    25201 atgatcgtga aaaattcgaa gcacgcaaag cacaaatcac acatatccaa gaagagttga
    25261 atcagcgatt tgatcaagaa cgaatcaaag tagatatgta tgatcaatat tacaacatga
    25321 aagaaatcat tgaaaaagat atgagcatcg tggaattagc gaaacaagca atgatcgagc
    25381 ttggtatctc tccagtgatc gaaccagttc gtggaggaac agatggttca aaaatctctt
    25441 acatgggtat tccgacgcca aatctatttg ccggaggaga aaatatgcac ggacgattcg
    25501 aatttgtttc tttacaagta atggaaaaag caacagacgt gattgtaaaa attgcagaat
    25561 tgaacacaaa gagttaaaat cgaaaaagaa cagcttatga caaggcgttc gtcccaatga
    25621 tggaatgtca tctgtctaag gctaaagggc aggacaatgg aattggttgt cccgccctct
    25681 tttttgaaga gtaaatagga ggtaaagaat ggaaaagctg ctagtttttt ataacaaaag
    25741 ttcagggaaa gatgagggtg agaaattagc acgctggttt caagattatg taaaagaaaa
    25801 gcagccagaa ttatatgtag aactagctga aactggccca tcgattgatg atgcggaatt
    25861 agtcaagaaa gcagaagcca tagaagctga tactttagta attataggtg gagacggcac
    25921 gattcatcat atcgtccaag cgttccaaaa aacattatct caataccatg tcggattact
    25981 tccaggtgga actgtcaaca accttgcacg tgttcttgag attcccctca aaaaagaaga
    26041 agctgctgac gtgatcctgg aaggcaatgt acggaaaata gactatggtc aagtcaatga
    26101 tgaagtcatt atctctacac tgacaatcgg aatcttagca gatacagcag tttggatcag
    26161 tcaagaagaa aaacagcgtt acggctcgtg gatctttatc aagaagtttt ttaagttatt
    26221 gctgaagaag aaaaaatatc atttggattt agaaacagac gaggagcatt ggaaaggaaa
    26281 atcccaactg ttgacagtca cgatgtctaa ctccgtgggc ggttttacaa attttgacga
    26341 ctcagcgacc ctagatgatg gaaaatttca tgtaacgatc gtaccttcct tagatatttt
    26401 ccgatttatt ttttatttgc ctagaatcat gagaggcaaa ttctatacga tccccggcat
    26461 tacttatttc acagccaaac gcatgaaaat ccaagcgcag gaaaaatctg tgggcactcg
    26521 aacggatgga gacacgacag atgatcttcc agttgaatta tctgttgtat caaaaggatt
    26581 aacagtttat tcaccaaaga aagaagaaaa agcttagaaa tagtagttaa cagaaagttg
    26641 gaagaagagt aatggatgta ttgttacaca atcctttgtg gttttacctt ttcattgtga
    26701 atttttactt attttgtctg atggggtatg ataaacatca ggctagaact agcggctggc
    26761 gtgttcctga gaataatttg atatttgtca gcctgttagg cggtggtttg ggaggattga
    26821 tctctcgaaa agttttccat cataaaactc ggaaaaagaa gtttactata ggattcgctg
    26881 caggtgtact tgttgatttg attctcattt attttttcca ttaaggagca ggagatgtcg
    26941 tctaaaggaa cgaaaactaa aatcattctg aatctgcttt tgctgattgt gatttttgcc
    27001 attatttatt atttaatcaa tcaatcattt gcagatatct ttgccgaatt gctgtctacc
    27061 agtgttgttg ttttggcagc ggctgttata ttagggacag tttaccaaat cgctgaaggg
    27121 cgctcaatca aagaaattgc tgaacctttc gcgccgaatt ttacaacgaa agatgggttc
    27181 ttgacctcta gctatattgc gttttaccga atcgtttcgt ttggtacagg aacgctgatc
    27241 tcggagattt atttttataa caaaaaagga atgaagctat cccagggagc aggggtgaca
    27301 gcactccata tgattatgta caaactggca gtgatcactt atgcattagc tggcttggtc
    27361 atccaattct ctctttttta ttctaatggt ccatcaatga tctggtttat catcgctggt
    27421 atccttttga cgatcgtgat tgttgccttt ttattggcga tgtccgtcag cttgaatgtt
    27481 caaatatttt ttgtcagctt atcgaataag ttatttaaaa gtgagcgttt gcggaaatgg
    27541 gtggatacat gcaatcagca gatctactct ttaagggaaa cggtccaaac cattatccaa
    27601 gacaggactg cgctattgcg gatttatcta tggaatatgt taaaacttgt attttggtat
    27661 gtacttcctt atttgattct gattgaaaac catcctaaaa tagattttct actgaccatt
    27721 tcgtttatca gctttgcagt agtgctttca ggggttattc ctacgcctgc tggtattggt
    27781 tcctttgaat ttgtctattt gttattattc agaccagttg ttggaacagt tgacgcagtt
    27841 tcttcgcttt tactgtatcg tttcagttcc tttatcttgc catttctcta tggatttgtg
    27901 tatgtgattg ctgaacggcg aagagtgatc aaagaagaaa taatagaagt aaaaaaagag
    27961 aataaagaaa atcaagggta ggtcttttat aagatctacc ctttttatca aatcaaagaa
    28021 aaacgttatg gataagataa ttttacgttt gtttggctct ttttttatat acatacaatc
    28081 aattttgttt ttttaagatt tatataagtc gagaaaaaaa gtcaaaaaac tatgtgtata
    28141 ttttgaccaa aattgaccaa agcgatataa tagtttttgt aaagatcaaa gaaataagtg
    28201 atcttacctt taattaggag ggtatacctg tatgaatatt gagaaaatga ctacgacgct
    28261 tcaagaagcg attgctgaag ctcaacagat tgcggtcact cgaaaacatc aagatatcga
    28321 cattgcccat gtatggaaaa tctttttaca atctaatcat tttggtcgaa atttctatac
    28381 ggatgccgga ttggatgtcg aatcttttga acatgaaatt gatcgtctac tggatgagta
    28441 tccagttgtt tctggtggaa acgtccaata tggacaaaac ctcagccaga atttctttcg
    28501 attattgaat gaagcagacc aaatacgtga aagcttcggc gacgagtttc tttcaacgga
    28561 agtcgttatt ttagcgttga tgaaattaaa aaattatccg ttaactgttt atttgaataa
    28621 aaacggatta tctgaaaaag aattgcgtaa aaacatcgaa gagatgagag gaggagaaag
    28681 agtgacctca caaaaccaag aagaacaata caaagcatta gaaaaatacg gcgttgattt
    28741 agtacagcaa gtcaaaagcg gaaaaatgga tccaatcatc ggtcgtgatg aagaaatccg
    28801 tgatgtcatc cgtattcttt cacgaaaaac aaaaaataat cctgttctga taggagaacc
    28861 cggtgtaggg aaaacggcaa tcgttgaagg gcttgctcaa cgtatcgtac gcaaagatgt
    28921 gcctgaaaat ttaaaagata aaacgatttt ttcattagat atgggtgcat tgatcgctgg
    28981 agcaaaattc cgtggtgaat ttgaagaaag actaaaagca gtcttgaaag aagtcaaaaa
    29041 aagtgatgga cgtatcctct tgttcatcga tgaaatccac aatatcgtag gggcaggaaa
    29101 aacagaagga agtatggatg ccggaaatct gttgaaacca atgcttgctc gcggtgaatt
    29161 acatttgatc ggtgccacaa ctttagatga gtaccgtcaa tatatggaaa aagacaaagc
    29221 gttggaacgt cgctttcaaa aggtattagt caaagaacca acagtggaag atacgatcag
    29281 tattctgcgt ggattaaaag aacgttttga gatccaccat ggtgttaaca tccatgacaa
    29341 cgcattagta gcagcagcta ctttatctga ccgttatatt actgatcggt tcttaccgga
    29401 caaagcaatc gatttgatcg atgaagccag tgcaacgatt cgggtagaaa tgaactctat
    29461 gccaacggaa ttagatcaag ttactagacg tttgatgcag ttggaaatcg aagaagctgc
    29521 actgaaaaaa gaatcagatg atgcaagtaa aaaacgcttg aaaaatttgc aagaagaatt
    29581 agctgaactt cgtgaagaag caaatgcgat gaagatgcag tgggaaacag aaaaagaaga
    29641 agtcaattct gtttcagcaa aacgtgctga aatcgataaa gcaaaacacg aattagaaga
    29701 tgcagaaaat aactatgatt tagaacgcgc tgctgtattg cgtcatggta cgatacctca
    29761 attagaaaaa gaattgaagg aattagaagc taaagcaaaa gacagcgaga ttaagatggt
    29821 tcaagagtcc gttaccgaaa atgagattgc tcaagtcgtt ggcagattaa cgggtatccc
    29881 cgtaacgaaa cttgtagaag gtgaacgaga aaaactaatt aaattgaatg aaacacttca
    29941 taaacgagtg attggtcaag atgaagcagt tgatgcggtc agtgacgcgg taattcgttc
    30001 acgggctgga ttgcaagacc caaatcgtcc tctaggttct ttccttttcc taggaccaac
    30061 tggtgtcgga aaaaccgaat tagcgaaagc gttagctgag aacttgtttg actcagaaga
    30121 tcatatggta cggatcgata tgagtgaata tatggaaaaa catgctgtgt ctcgtctagt
    30181 cggagctcct ccaggctatg taggttacga agaaggtggt caattaacgg aagctgtcag
    30241 acgaaatcct tatacaatcg tcttgttgga tgaaatcgaa aaagcgcatc ccgatgtctt
    30301 caatatcttg ttacaagtcc tagatgacgg acgcttgact gattcaaaag ggcgagtagt
    30361 agatttcaaa aatacggttc tgatcatgac cagcaatatc ggttcacagt tactgctgga
    30421 aggcgtgact gctgatggaa cgattccaga agcagtggct gaacaagtca acacgctatt
    30481 acgtggaaac ttcaaaccag aattcttgaa ccgaatcgac gacacgattt tatttacacc
    30541 attgagccta gacaacgtga aaggaatcgt tgacaaaatg gtggcgcaat tggcacaacg
    30601 tctggaacat caagaaatcc tgctgacaat cagtgatgaa gccaaaacgt ggattgctga
    30661 aaatgcttat gaaccagcat atggtgcaag accattgaaa cgatttatca ctaaggaagt
    30721 agaaacacca ctagctaaag aaatcgttgc aggacatgtt atgcctaaat caaaagtaac
    30781 gattacttta cttgatggac aacttcattt caaaacagaa gagctagaag aaatcgtcta
    30841 atcttccatt gagactataa aagaaaaaag gggtctgaca caactagtgt cagacctcct
    30901 tttttcaaat aaacagtgtt ccagaagtag tttcttcgaa aaataagccg aaatttcttg
    30961 aagctgcccg cttctgtcac aacctctttt attaggtatt tttcactttt tctaatttat
    31021 aactttcaaa gtaacgctca tcttttttac tttgagacca tgcaaacaat cccattaagg
    31081 cagcacctat cgtatttgtc agcaagtcgc ccatcgtatc catcaatgct gctcgtccga
    31141 caaacagtgt gccatcagaa gcagcaaaac gttgaagatt catgcctaag aactggtcgc
    31201 ataagaattc ccagaactcc caaaacacgc cgcaaagtcc agcaaacgca aagccgaata
    31261 agaggaacaa ccaaggactg gtttttgata tctcagcatc tttcatcaag taaccaatca
    31321 atccatagcc aagagctgtc aggaccattg gactcaccgc atgtaagatt ttgtcccaaa
    31381 aagagatgat actgatcaaa tgcatccctg tgcctaaaaa gacagagatg aacaagaaaa
    31441 accagtaaaa caaaacgatt gctgctggta ttttaagttt gaaaactttc aaaatgactt
    31501 gtggcatgaa aatcaatgca atccctaata aagattccac gataaatgtg attccttgag
    31561 aagtcgaata tttttgtgtg ataaattcat aaaaattata gcagacaacg aatacaccaa
    31621 aagcaagtaa agctatttgc acctttttga tttctttaat cactgaaagt ccctccatct
    31681 aaaaatcttt ttacttctga aagcaactca atttctgaag aaaccacttt tccgttcaat
    31741 ttgatcaaac ctattgtata taagttcagg tagtgaaatt gattttcagc tgtttcttgt
    31801 agtgcagcga tttttttcgg gtgggttccg ccttgctgtc gagtatcagt atataagccg
    31861 atcactggga tgcctttcgc ataagccaca ccgatttccg atgctacccc ggcatcgatc
    31921 gtcagcccat ctagtaaagc aatcattaaa tcactagcca acactttttc tgtgtcagca
    31981 agagcaatca ttcgactgtc tgcataagca gttttgtcat tgattgcttc attttcttga
    32041 ggaagataga tcgaaagctc agaagagagc tctctgattt ctttaactaa ctgttggtta
    32101 tataacaaat cacttttagc aaacattggt gcggcaaaat aaattttcat ctaaacatca
    32161 tcctttttat caaaaataat cgctaaagta agcttccatg tttggaatga tacgctctag
    32221 tgacttcagt gtttcttcat ctgtttctaa ccgttcgatt cttgccaaat aagaagcacg
    32281 gcgataattc atcatcaagc aagtcaatgt ttggatatcc agtcgaacgg attttcctat
    32341 aggttcattt aagacacgga cttgtccctg ttcatcccat gttaaagcga agacaccatt
    32401 attccaagga gcgacaggat cttcaatgat gaaatgaaaa gcatcagctg ttccaacaaa
    32461 cggaaaccgt tgaaggaatt cttttacatc aacgatccga gccataaaat atggttcgat
    32521 ctgctctttg atctgactat cttcaatcaa aaatgctaaa ggctcatttt tataaatatc
    32581 tccatgtacc cagtagatca tggaaaaatg tgcggaaata aagttccata agccatttcg
    32641 agcttcttga tcaagataga acatttcttt tacgtgaaat atttcttcag ctacccagta
    32701 gaacagaaca cctcttggtt catggttgct atcgtagtag acagcggctg tgcgctcatc
    32761 ttcattttcg aaacgccaat actcttccca atgaaaatca ctgcggaata aagcaccatg
    32821 gttttgttgg gcaaatttgt cataaacgga aaatacgtct ggatgatcaa ctggtaatcg
    32881 ctcaaccata ccacttactg ggatttgttt aggtagctgt gtatctctga ttttaaagga
    32941 aagtttatca gacatgattt cccatccttt acgccgatag taggggatac tgtaaggata
    33001 caaataagag atccattgct tattcttgcg catattatcc aatgcaacga taattagatc
    33061 ttgcatcaat ccatggttag catattctgg ataagttcca actccagtca caccacccat
    33121 tttataacgt gcaccgtgaa tattgacttc acaaggatag atagcgattt gagagatcag
    33181 tttattttcg tggaaccatc cgaacacttt cgatacttcc aaaatcggtt ttttggaacg
    33241 gataaaagct cgtttattct caaacccgct ttcctcgatg tctgcttcag tcacttggaa
    33301 cacataggaa agcaattcat tgaattgatc gatatgttct tgagtgaccg gttttaattc
    33361 aagattttct ctaaaatctt tttgatccat tttttcatct ccatttatta gcttgataac
    33421 agtatagcaa aattctacaa aaaaaacttc tatagctgac taattaaaaa ctctttaaat
    33481 tactgctttt cgttggtata atggaaagtg ctgattatat gaaaagagga gacgctatgg
    33541 atataaagaa aatgaaagaa cgccaagagc agattcgtaa tttttcgatc atcgctcata
    33601 tcgaccatgg gaaatctaca ttggccgatc gtattttaga aatgacgcac actgtgacgt
    33661 ctcgcgaaat gcaagatcag ctgttagact cgatggattt ggaacgtgaa cgtggaatca
    33721 cgattaaatt aaatgctgta gaactcaatt acacagcgaa aaatggagaa acatatatct
    33781 ttcacttgat tgacacccca gggcacgtcg acttcaccta tgaagtctct cgaagccttg
    33841 ctgcctgtga gggtgccgtt ttagtggtcg atgcagcaca aggaatcgaa gcacaaacat
    33901 tggccaatgt ttatttagcg ttagacaatg atttggagat cctgccagtc atcaataaaa
    33961 tcgacctacc cgcagcagat cccgaacgtg tccgtcaaga aatcgaagac gtaatcggaa
    34021 tcgatgctag tgaagctgta ttagccagtg ccaaatcagg gattgggatt gaagatattc
    34081 tcgagcagat cgtggaatat gttcctgcac caagtggaga cttagatgca ccgctaaaag
    34141 ctttgatctt tgactctatt tatgatagtt accgcggtgt tgttctaaat gtccggatca
    34201 cggacggtat ggtcaaaccc ggagacaaaa tcaaactgat gagtaatggc aaaacatttg
    34261 atgttacaga ggtcggggtc ttctcgccaa aagcagttgc tagagacttt ttgatggtcg
    34321 gtgatgtcgg ttatatcaca gcaagtatca aaactgtcca agatacacga gtaggggata
    34381 cagtaacgtt agcagacaat cctgccgctg aagctttacc aggttaccga aaaatgaatc
    34441 cgatggttta ttgtggtctt tatccaattg atacttctcg ttacaacgat ttgcgggaag
    34501 ctttagaaaa actgcaattg aatgatgctg ctttacaatt cgaaccagaa acctctcaag
    34561 cattaggttt tgggttccgc tgtggattcc tcggacttct tcatatggat gtcgtccaag
    34621 aacgcttgga acgggaattc aatctagaat tgatcacgac tgcaccatcc gttatttacc
    34681 atgttaataa aacggatggt acgactgcta cagtagataa cccggcagat tttcctgaac
    34741 ctgtaacgat tcaggatgta gaagaaccat tcgtcaaagc acagatcatg gtcccaaatg
    34801 attttgtcgg tgcagtaatg gaactttctc aacgaaaacg gggagaattc attacgatgg
    34861 attatttaga tgattaccga gtaaatgtcg tctataatat tccgctttct gaaattgtct
    34921 ttgacttttt cgacaaattg aaatcaagca cgaaaggcta tgcctcattg gattatgaaa
    34981 tgtctggtta tcaaaaaagc aagttagtga agatggacat cttgctgaat ggagaaaaag
    35041 tcgatgcatt aagctttatc gttcaccgag actttgccta tgaacgtgga aaagcaatcg
    35101 ttgaaaaact gaaaaaacta atcccacgcc aacaatttga ggtgccaatc caagcagcta
    35161 ttggacaaaa aatcgttgcc cgttcagaca tcaaagcctt gcgtaaaaac gtcttggcta
    35221 aatgttatgg tggagatgtt tctcgtaaac gtaaactctt agagaaacaa aaagaaggga
    35281 agaagcggat gaaacaaatc ggctccgtcg aagttccgca agaagccttc atggccgttc
    35341 tgaaaatgga tgagcaagat agtgtgaaat aacttataat caatcgaaaa acctattaaa
    35401 taaacctttt tgagtagatg caacactgag gattatctgt ataaaagatt ttaaactgtc
    35461 atttggttat cacggcgata ctaaaattaa caaaattgga atatttttct tgaagatttt
    35521 tagctgtcag tatatgatga aagcatctca taggaggtgc ttttttcatg gttgataatt
    35581 caagtggaag ggttcttaaa tctctaagaa aagagaaaaa actatctcaa aaaaagttag
    35641 ctgatttagc aggtatttca caaagtactt tagttaaata tgaaaaaggg tcaagaaaaa
    35701 tccctaaaga cgtagataat actctaagca agattctgaa tatagaaact ctaataaaag
    35761 atgaggaaga taagattgag attctcatcg gtaaactaat tgcatacaga gatatgaata
    35821 agttacttaa caaagagtta gctgataata taggaattag tgaagtatta ctcagttatg
    35881 tgttaaatag aaagagaaat ccgtcaaaag aaatgcaaaa aaaaatcgat atttttctat
    35941 taagtaatga aaaagaaatt ttgaaggaga ttaatcgtga tagtgagata tttagtttat
    36001 caaaagacga taaaattgtt atgggaaaaa gaatacgaga agtccgaaag aaccgggaag
    36061 agacgcttga aaaatttggt aaaaacttta ccatctatac aggcaaaaat gttataagta
    36121 gatgggaaaa aggtattaat attccagata ttgaaaaact aatgaatatt gcctatcttg
    36181 gtaaggtcac tgttccttac cttatgtacg gagaagatta taagaatata cttccaaaag
    36241 atgaaagagt tagcgatttt aaaaagataa attcttttag tatgggatta aggatgagga
    36301 aaattaggaa agattattat ctagaaaggg aggagtttgg aaagcttttt tctccttcaa
    36361 tttcaaaatg gtccatagat aggtatgaga atggtagaga tatacccaat actaatcgaa
    36421 ttatccaata tgcttatata ggaaatcttt ctttagaatt tttgatttac gggatataaa
    36481 aatagtttac gtcgatactt attaagttat cgacgttttt tattatagaa aaaatttata
    36541 aaaggaggtt tcttgatatg ataagaaaca aaaagggttt gttgaaagtt gctttactgg
    36601 cagctttttt ctaagtaact ttttgacaag ctcaatggca acacaagcgg aagaagtaat
    36661 acaagaacta actgttatga ataacagcta gataaaatgg gctatgtatg ttatccaaca
    36721 atttagtaat cgctagaagc ctagcgaaag ttcgcttgat aagttataga tgagtattga
    36781 tttgtagtgt ttccaaatca aaagggtaca gagccacatg aaatatgttg tcctctgcag
    36841 cgtcaggatg ggaatccata ccatggagat tcggagatct gtgagggaat acttacgtgg
    36901 ttaatatgtc agttgtgttg gacgtagtaa tggtcatagt gggtagattg actgaattct
    36961 tatatgagaa aatgaaacca acaagaagat agggttattt atacagaatt ggggatcttt
    37021 tctggaaaag taatcggata atgcgagatt cgtacggtct tttttaaatt tctctaaaaa
    37081 aaacggcatc gaatgggttg ggtgattgat aagcaatgaa tcatagactg atatagaata
    37141 aaaaatgatt ctatttatct ttttacatct atcgtttttt caagtagccg caaattatat
    37201 cagcattcaa caatttttgt atacaagttc tagtaaaagg atctgaagaa aaagttggtt
    37261 gttgtgaaga taaaaaaaga atcaggtttt actgagtttt tcttcaaaat ttgtgttatt
    37321 aggttaggac aaagataaga agaagtatga agatttaaaa aaggaatgag gaaaagatag
    37381 taatttccga ttattggagt ttttttattt ataaagaaga agcgaataag ttgtgattcc
    37441 tagatttcgc gcgtgattaa ttaatgagca aaaaatgcgg aaagttttag tgtttaatac
    37501 acgaggacaa agtttcttag gtattgaagg cacacgtgta acggttgatg ggtggtgtga
    37561 ttgtttcgag gttggaaaac atgttgaact tatggcattt actgagctaa aagataagaa
    37621 caacgtggaa tttttcgaga gtgatattgg ttgggacgat catgaagaag tttatggaaa
    37681 atttattttg cggaagggaa attcttatac gaatggggaa gcataagtag cgatttgtta
    37741 gagatcattg ataggattga aattgtcggg aatatttatg agaatctaga gttatttgag
    37801 gtgatagaat gagtgatggt tttgaacaag tatcaataat taaaaatcaa gttcgggaga
    37861 ttcttagaaa aaaaggctat ttggtagata gttattttga aggagattac gaaacatggg
    37921 taggtgtcta tgctcgtcca gagaataaac ctacctattt agatcctacg acgtcagaag
    37981 atgcctattt acaaaatagg tatcgagtag atggttttaa gcaagacttt gcggagtggt
    38041 ttgaatggga aattgaaaac ggagaagtaa aagaagaata agagtacttg ttgtatcaaa
    38101 ataagccagt agaacaacca aaccagtagc tagtaatgac aataatactg aggaatcgga
    38161 tcattatggt atgattgata tttctcttcc agaagatctt aagccagatc ctgtaacaat
    38221 tggcaatagt gtcatgattt ttgattcatt agatgaagct atgtcatatg gttggaaaga
    38281 aattaaggat gaaggtagta attggtatgg catgagattt ggtgatggtg aagttgccaa
    38341 aaaagctggt attccaattg ggaaatggac agttgatttc cacgaagcag gttctttttt
    38401 tgttctgtaa ttatagtggg agggtaaaat cattgatgaa atgtgttcag ataagagcgc
    38461 cagataaaaa tagaagagac agttcacgtc gttatcactt ttggtaacgg cgttttgttt
    38521 tattatataa aattctcagg aaaaggagga attcttgtgt atgcaaaaac gaaaatgaat
    38581 tggttgaaag cactcgcatt ggtggctttt tctcaattct gtttcttggt gggaactgct
    38641 caagcacatg cagaagaaac gacggctata caacctacga tggaagccat tgcccaagtc
    38701 gcttctgaag tgacagaagt ccaaccagca gaagccgggg tcccagctgg tgaagccact
    38761 gttgaacagg cccctgtgac agaagcgcca acggtcaatt ccaaaacgac tctcgatcag
    38821 acgattgggg aaacacaaca cccagggaat agtcctggta cttcacaacc agttgaagaa
    38881 actgcctcaa ttacaacccc tgcttcagaa acgtccactc tagaaggaga aaaagctgcc
    38941 gaagcaacgc cttctgtgca gccagagtct tctgagaaac aagcggaaga aaagaaacga
    39001 atagaagaaa cagtggaaca accagcggct actgctgaca aagaaggaaa aaatgaggaa
    39061 aacgttgaaa aaacaatctc ttcaaccgca gctagtcaaa atcaaccaac gaaaccaaac
    39121 aaagaatcta cggctagtat tgaaaatcaa aagaaaaaag agcagaacat tccaaaaaca
    39181 ggtacaccta cactgttagt aacagtacca accaatcgtt cggttcgtgt tcgccgtgca
    39241 accaatgcag ctgttttagg tggtcggaaa attgattggg gcgaaaatat tggtgttact
    39301 tctagtccga acaatctaaa cttcacttta aattatatgg ttcgttttga gattaatgga
    39361 caagtggcgt tttgtattga gcctggtgtc tcagccgcag aaggtcaagt ttatacagct
    39421 actgctttga aaaactattt gaaaaattca aatgtacgga aaaaaacaag cttgatctct
    39481 tatttaggat atgtcacaaa taaagacaaa tccgatgaac aatacattgc ggcacaattt
    39541 atgatttggg aagctttggg cacaaaaatc ccaatcaaaa atatccgtgt tgattatgat
    39601 cgtcgaaaag cagaaattca acgtttgatt aataactttg gtgaaaaagc aacttttaat
    39661 aatcaaacac atacggtaaa aattggcgaa acgttgaaag taaagaataa aaatgatttt
    39721 ttgaaatatg tgaaagacat tcaaaaacca aaaggtgtca atgtatctat tcacggcaat
    39781 gaagtatgga ttacagtcac aaaagaggca ccggataaag caaaaattca attgaataaa
    39841 attaaagttc aaggtgcgcc attagcctat cgtcgtccag gagctcaaac aattggtgtg
    39901 ttacatccaa cagaacctaa tgcgtctgtt attaatttac aaattctaaa acaaggaaac
    39961 attcgtgtgt ttaaagaaga tgcggaaact ggtgtgaaag cacaaggtgc agcttcttta
    40021 gaaaatgcgg tctatggttt gtatcaagca gatgggaaaa agattaaaga aattaccttg
    40081 aaaaaaatta acggcaaagt acaggcagaa attaaagatc ttgatcctgg caaatatgtt
    40141 ttaaaagaaa tcaaagcgcc aaaaggttat gtgctttctg atgaagcaat tgaaattgtt
    40201 gttgaacctg gaaaaactgt caatgcgacc gcaaaagatc aagtgatcaa aggaaccatt
    40261 gatttagtga aagttgctaa taaagattta gtcgattcaa cgaatccaga taacaaacca
    40321 aaattagctg gcattgaaat cactttgacg tcaaaaacaa ctggcaaagt ggtgaaaacc
    40381 gttgtgacag acaatgatgg ttatgctact tttggtaaaa ataccgttgt ctttgatacg
    40441 tacattcttt ctgaaaccaa aggaaaagaa gggtataaac tatttgaacc acttgaagtc
    40501 acaatttctg aaaatgggca aactttccat tatgttttag aagataaagt aattgaacaa
    40561 cgtcttaaag tggtgaaagt ggatcaagaa acaggaaaag tgattccact tgctaataca
    40621 gaattcaaga tttttgatac tttagccaat cgttatgtca caatggagat tccaaatgat
    40681 acagaaacaa cggatatctt taaaaccaat gaaaaaggct ttttcctaac taacggtaca
    40741 cttacttatg gaaaagatcg ctatcgtttg gaagaaatca aagcccccgt aaattacgtt
    40801 ttgaatcaaa acccattagt gttctcgatt accaatgata cagaaccgat caaagtgatc
    40861 cattttgcga accgtcaagc acggaaaagt gtaaaattat tcaagtatga agaatggaac
    40921 aagaagaaaa cgccgctcgc aggtgtgaac tttaccttgt ataacggtaa aaatcaagca
    40981 attggtgaat ataccactga tcaaaacggg gaaattttag tgaaaggtct agttgccgat
    41041 gactattact tcttggaaaa tgccccatta gaaagtttcc aaccaaatac agataaacaa
    41101 gcattcacgg ttgcattcaa acaaaatgcg ccagatgatg gggaaacgtt agtggtttct
    41161 gtacgtaatt acttgattcc accaaaacta gaaacacaag cgtcaaataa agccgatggt
    41221 gaaaaagtgg ttgatccatt agaaacgatc gtcattaaag acagtgtttc ttataccaac
    41281 ttgtttgtcg gaaaagaata caccatttca ggagtattga tgaacaaggc aacgaatgcg
    41341 ccaattttac aagatggcaa agaaatcaca agtaccttgg cctttattgc agacaaagtc
    41401 aatggcacaa aagaccttga atttgtggtt aatgctagtg ttctgaaagg tcaaacgatc
    41461 gttgtttttg aaaaactttt ccgtgatggc attgaagttg cagcacatgc ggatatcaac
    41521 gatgaagccc aaagtgtgaa agtgaataat ccaaccgttc ataccacggc tgtctttgaa
    41581 gacggattga cagtcgcaga cccaacagga ttgtttacct taaacgatac cgttgaaatt
    41641 accgagattc ttccaggaaa agcatacttg gtcaaaggga tcttaatgga taaagcaacc
    41701 ggtgaaccct tgcttgtgca tggaaatacg gtagaaacga gtgttggctt tattgccaaa
    41761 gcagaaaatg aaacggtgat cgtaccattt acctttgatt tgacaggtat aaatggtcgt
    41821 gaaatcgtcg tgtttgaaag tctttttaga aatgatgaag aactagcaaa ccataaagac
    41881 atcaacgaca aagggcaaac ggtacgagta actaacccaa gtgtacgtac aacggctaca
    41941 cataaaccca ctggcttgaa agaggttaat ccattaacga aagtcaccat tacagacgct
    42001 gtgaaatacc acgatttggt cgttggaaaa acatacacag tcaacggtgt tctaatggac
    42061 aaagtaacgg aaaaaccagt gctagtagat ggaaaagaag tcacaagtac cttaacgttt
    42121 gtggcagaaa caacggatgg tacagtcaat ctagacttta ttctagacgc acgtgcgttg
    42181 cgaggcaaag aagtcgtggt ctttgaagat ctgtttagag aaggcgtatt attggcttct
    42241 cacgcagata ttaccgacaa tgaccaaacc atcaaaatca gtaatccaac cattacgacg
    42301 aaagcgacga ataaaaatgg cggaaaagag atcttggcct tgccaaatca aactgtgctt
    42361 gaatgggtca aagtagacgg tcttgcgatt ggtcaaatct atcgcttaat tgttcaaggc
    42421 tacttaacac cagacggcac accatttgaa ggcactcatg cggaaaaagt ctttgcggcc
    42481 gataaagaaa tgatggaatt cttatttgaa ttcttagtgg acggtcgcaa tcttgcagga
    42541 aaaggcttga gttttgcgga atggctccaa gcgaaaacgg aagatgagaa agaaacgttt
    42601 gaagaagtgg cgaaacacaa tgtagatcta acaaacaaag atcaaacggt tcaaattgtg
    42661 gaagcgccaa aaccaccgca accagtgaaa ccagaacaac gggttaaacc agctactgtt
    42721 gtaccaatgt tgccaaaaac aggtgaacaa acaagtagta tacttatggt tcttggatta
    42781 gtagtattag tcattgcttt aggtataaca ctttataaag tacgtaaagc caaagattag
    42841 tcatgaggaa caagcggtta ggatttttaa ccgcttgttt gattgtaatg tagaaatatt
    42901 tagaatttat tttggttttt aagaggagga aaaactttat ggcagaaaaa gcattgcgta
    42961 tgaagaaaga gtttttaggt caagtatttt tattgggttc acgggaacct aatccaccaa
    43021 aggaaattaa tggtgtgtct gggcgatatg ttcaattaca agcagagtgt tcgcgagaag
    43081 aacagcctgc tttttttgtt tatctcacag ctgaagagga taaaagatta cgattaccag
    43141 aaaaagaggt gcgtatttca tttgaagaag cttattttgt ttttcgtaaa gaacgagtga
    43201 atagtcgtga aacaaatgat atgggacaaa cagagcgtcg aacaactggc tatcaagatg
    43261 ttggtgtctt tttaactggt gtaaaaattg gggaggtttt gtaagatggg attaaaattt
    43321 ccaaataatt atgacattac agaagcatta gatgaaactt gtttaggagc cgtacgcttt
    43381 ggcgcattag aagagtctga tcgtgtattt gataatgaaa caggcgatta tacgggagaa
    43441 attcgatcac agcgagcaca attagttttt ggaaatccag atgaaccaaa gattgcacga
    43501 cgagttaaat ttccagcaga tgtagatttg actggtttta aacgacgtga tcctgtgaaa
    43561 ttaattgatc cagaatatca tgtggtatat attccagcac aagatggcaa tcgtgaatat
    43621 tcagatttag tgatttatgc gaaaggatta gagaaagtag aagctccaac aaataatcct
    43681 aatatgaaac aatcacaaga aaaaggttta gatcaaaaac aaccaagtgt tgattctaag
    43741 gaaaaagaga aaaaataagg tttttttgaa agaataggaa ggagtcttcc tattcttttt
    43801 atctaagata gaaggaaggg gagattttga attcagataa aaccaatcaa atactttgag
    43861 agattgtgct tgttatcaaa atatccaaca attgattgag tattttggag acaatccaac
    43921 gatttttgta caaacaaatg catatatttg tgcggttatt gggcagtgta tgtttttacg
    43981 tgatcttgtt cgtttttcat taccgtacca gtggaaacaa gatcatcagg aagtgatttg
    44041 gattcgtata gtacgaatat gtaatatgtg tgcacaccct tataaaaatc gattaaatct
    44101 ttttcgatta tgttttttta ctaaatgtga tattcctgta ttagttgctt tttgtcaaaa
    44161 gtttttagca caggaaaagt aaaaacagaa aggaggaatg tgacaattga aagctcattt
    44221 tttcaagtat cgtggtcggc gaattcgcta tttcaatcgt tatttatggt tttgctatta
    44281 tggtttcttt ttgtttccat ttttgattct gttaggttgg tttagttgga aagtatttta
    44341 tccacgttta agtacgtttt cgaattggca aatgtatctt attcctggaa taagtattgt
    44401 gttgtatttg ttgctggtta gtgggttaat tttagggttg atgcattggt cgcgactaaa
    44461 agaaggatat tttgcctctg tttattggcg tcagttactt gttcgaatgt taattgacaa
    44521 tcggtttgtt tatacaaaga aacaagttag tgagaaacaa acaagggaaa aaatgagatt
    44581 accaaaagtt tatttttatc aaaagaaaca agaattagtg gtttcttttc ctttagatgg
    44641 tgggcgtttt cacgaacgat ttttaaaaat gggtcatttg ttatctgaag tatttttgcg
    44701 tgatttaatt cgtgaagaac gagaaaaagc ccgaatcaat tatgtattcc tttcagattc
    44761 tggtcggatt cctattgatc aatgtatagc agaaaatgga cgtattcatt taatgaaaac
    44821 tttggattgg gtatatgatc aatcaccaaa tatgttgatt gctggtgcaa tcggtggtgg
    44881 gaaaacctat ttattgtatt ctttaattca agcttgttta agtgttggga cagtagatat
    44941 ttgcgatgga aaagcggcag atttagcagc attaggtgac gtcgatgtat tcaaaggaca
    45001 tgtgttttac aaaataaatg aagaaatgat tatttgttta cgaaatgcat taaaagaaat
    45061 gaatcaacgg tatgcctata tgaaaaccat gaaagatcct aaatatgaac cagggaaaaa
    45121 ttatgcttat tatgggttac caccgcattt tatctttttt gatgaatggg cagcttttta
    45181 tggttcgttg gatatggaag cgagaaatag agtcgataaa ttgattcagc cattagtatt
    45241 aaagggtcgt caagcaggga tgtacattat tttagcaatg caacgaccag atgcagaata
    45301 ttttccaagt ggtgttcggg ataatttaac attccgtatt tctgttggtc gattgtctcc
    45361 cattggttat ttaatgactt ttggagaaga ttttaaaaat aagccatttt acaacaaaga
    45421 tcaacctggt cgtggatatg cttttccagg atttgatgta cctgtagagt tttttgcgcc
    45481 atttgtttac aaagattatc actttatcaa agaatttgag aaatttactg aaatgattgt
    45541 ctatgatttt acagtaaaag aggatagtca agatcaaacg atgggagatg ataatcagtt
    45601 gttacaagaa caactagagc gccaaatgta tttagcaaaa gatccaaaag gaacaagttt
    45661 ttctgatgcg catattttgt aatcaactaa ggaggtgaag ttaaatggca gagagttgtt
    45721 attatagagt agctacagca atacgaatga ttaatccttc tctttcttcc agaacgtttt
    45781 atgattggtt gaatcgtatt gaacaagtaa ctgattaccg ctttttgcgc aaagaacgtg
    45841 tttttacagg aaaagttatt aatcaagtat tgctaacgaa aaaagatata gaacgattga
    45901 ctcgattgta tcattatcga gtagatttag aagaggattt aactttgtca atttatcgcg
    45961 ttttttctcc tgaaaaatat agtgaaataa caaaattaga tcatttaatt ttgtagttat
    46021 tatctatcgg gagggctcta gacgtagtct ggtagccgca ctctgcctgg cggtgcgcat
    46081 taaggctgcg aagcatgggc ctataatgcg cactcgctag cagcgtgtgc agctcacaaa
    46141 gaggtcgtgc gcttgcgcac ggcctctttg tgtaaagccc cccgatatat aatatggggg
    46201 gcagaaataa cataacacat agaaaaaagt tttataaacc cttttgtatc aagtgattat
    46261 ctaaggtcag cagttgtact acttttccca aaaaacgagg gggactagtt gatatatcgg
    46321 tgtttctaaa gggttaaaaa aaatcgattt tgttatttta taaaaggagc gagaaaatga
    46381 caccgattga gctaaaaagc tacagaaaga agttaagtgc aattcataat ataagtggag
    46441 ataaaaagcc gctatcacaa gcaagatttg cgcaattgat gggctgctca aaagattaca
    46501 ttagaaagat ggaacaaggg aaaagaaaaa tcccagagga ttttgaacaa cgaatcaagg
    46561 aacgctttcg attgtatatg aaaagcggaa tagatcttcg agcaatgatt gattatttgc
    46621 gtctttcctt ttttgggaca gactacaaaa cagtgattca acgtgtatta cgaatggatc
    46681 tgacagaatt tgaaacacgt ccaacgggct tgtatctttt tgactgtctt tctgttcgtg
    46741 ggaatatctg ggtgttctgg cattcaaaac gaactgtaac agaaaatgta cttgtgcaat
    46801 tttcaggaca aggttgccgg gaatatgagg aagtcatgcg tgaacaacaa acagattggc
    46861 gaacatggct atattccatt tggaaaaatc aaggaaagtt ggaagctggt tatacacgtg
    46921 tgcaatgtag ccgattcgat attgcgttag atgaactttg gggattggaa acggaagaac
    46981 atttcgatct ctttgaatta ctagaaaaac aaaaagcagg tttattagaa atggacttta
    47041 agagattcca gaatattggc ggttgttttt tagatgatgg ctattttcga agtgaaggat
    47101 tatctttgta ttttggatcg cgaaagagtc ctctcttttt taatttttat gagaaacgtt
    47161 ttgaaattgc gaaccgagaa aaaatttcag aattagaagc attaacgaaa tatggtattt
    47221 ataatcgata tgagttacgg ttagccaatg agaaagcaac acaagcagta gaagcattta
    47281 ttttaggtga ttcaccgaaa cgtttaggag agattggcgt tggtttaatt aatgcaaaac
    47341 ttattgtttg ggatagactg gaaagtgatg cacggattgt tgataaacga tgggcaaaat
    47401 tatttcgttc gatggaagaa ttggatttta cagtaaagcc agaaaaattc tcattagatc
    47461 gttcagaacg ctggtttttg aaacaagtag ctccgacatt aaagttgtta caagaagcag
    47521 atcgtatttt aggaagagac tttgtacaag aagggattga taatgccgaa ctaaatgacg
    47581 agcaacaaaa ctatctagaa tggatgggaa cgtcaggagg gaaaattgca tgaatgcata
    47641 tacgacaaca gaatggctgc gcctgttgga tttaaaggct gcaatcgaag cattaaatga
    47701 aaagatggtt gatttgtctt attttcgttt tcgagttcct tatattgaac aagcggtaaa
    47761 agctggacgt tatcaggaaa aagagaactg gcaagaaatt gcacgcttat tagaagttcg
    47821 taagggatac gaacaagaac tcgaagagtt ggaatttagc cgaaggaaag gaaggctaga
    47881 attcattcgc ttttatcgat tttcattgcc aatacctgcg attttagcgg ttaaaaaagg
    47941 ctgcgataaa atgaagatat atgaaaactg tgtggcagca cttagcagcg aaaaacctct
    48001 tatggaagaa atttcattgg tgactgtcac ttgggaaatg agtcgccagc caacagaaga
    48061 acagacatat ctttctttag aagagattga gatagaatta gaggaaattg gtcgctatgc
    48121 cacttgttct acctattgtg gatcggtcat tagtattgct ggtgtgattg tctaaatgaa
    48181 aaaaattatg atttatgttg gtgcgtattg gtcacgtgat ccaacagtat tagaaaatcc
    48241 agaggcggta cactattgct tgcgccaatt attctatctg tataaagaac gattagaatc
    48301 gttgattcgt cagttaccat atactgacag acgtttagat gaacttcttc taaggtatcc
    48361 agcaatgtat aaacgacgaa aaaatagatt gttaccagaa gagtatccca ttgaaaaaca
    48421 tgaacttgaa gggcgatttg tggcttattt ctatgatgat gttcgtatgc gcttagtaga
    48481 acaacgaatg gaaatagaaa atgatcgcta ctattttatc aattattgta agaagcgtaa
    48541 gtatcaagta actgatgatt tttatgattg tattttacaa gatggggaag tgattctatc
    48601 caaaattgct ccaagttttc gtgaacttgt gccgattgat tttttgaaaa aatgtcattt
    48661 gcggattctt ccgtaaaaaa gagctataaa aggaaagaaa agtagaagcc aaatcggttt
    48721 ctgctttttt atttttttta ggaaggagaa gatggtatgt cactggaatt tttaggagag
    48781 ccaattgaaa aggaagagtt cgtttcgcat tatatggatt tgtttattca ggtgataaaa
    48841 aactttgtgc gattgatgaa ttttatccac gcgaacaaga ctatctagcc gctgaacgaa
    48901 taaaaatcag tttattatgg gaaaaattca cagatgaaaa taaccgaccg ccagattatc
    48961 gctatttatc agattgttta acgaataatg tgctttctaa agaataccta tttcacaaac
    49021 gtgagaaaaa tcaaatgtcg gttgaacatt tttgtgattg ttatattgca ttattgcgta
    49081 gtcaacagtt attaacagta gaacgatatg gtgcagagtt tggttatgtc ttgcaagctg
    49141 agcgtcatag agctacaaga tgctatgaaa aagaagatca agtgattgat ggctatgaag
    49201 aattatgtat tcgaaacaat cgctatttgc aacaacgttt atatgaacaa ttgatgatgg
    49261 atttttcaaa tctctataga gggtatgaat gttcgatgat tcaagaaagg tagaagaaaa
    49321 gggggaattt ttatgtggcg attattattt ttggtggtat gtggtatggc attgttctat
    49381 gtgtatcgtg tctatctcta tccacgaatg gaacgatgga caagttggta tagagatcct
    49441 ttaaaacaac gaaaaggatt gaagcggtat cgttatgaat tacttgttga attttcggat
    49501 gggcgacaag cacagtatta tttttttgca aactatccaa aatacaacac cagtgaacta
    49561 ttgattcaat tattcaaaaa taatccatat gttgggttag aagaaaacgg acgggagttc
    49621 ttttatcgtt cagataatat tagtgcggcg tctatgaaca aaacacgaat tgcataaaaa
    49681 attggaggaa taatcatgaa aaaaacaaca ttagcagtcg taacaacact aggaatttca
    49741 ttattttcgt ttcaattagg gagttcattg gtttatgcag atgaaactgt agaaacacct
    49801 aagtcagaaa ttgtagaaac attgccaggg gaaggattac cagatgttga gacagagcta
    49861 aatggaggaa caacggaaaa accagcagaa cctgaacaat tgcagtcaga gaaacctgaa
    49921 aaagagccag tgacaccaga accagagttt cctgaatcaa ctttaccgac tgattcgatc
    49981 gaagaagaag gtgtgcatag ttcaacaaca acggattcaa gtatagtcac aactccggaa
    50041 caatcaggaa caaccagttc ttctgaaaag aatactgatt cgtcaagtac ggaacagcca
    50101 acgatgtcgt ctaccagtga agaacaaaaa gaagaaccga aacaacctgt tgaaaaatca
    50161 gaagcaattc caaaagaaaa taaacctatt gttccagcaa aagaagtcac agtatcggta
    50221 accccaagcg gtgaaattac gacgaatact tctcaaggaa tgagtgtacc gattgtcact
    50281 agtaatgtag aggaattgac ccatattcca acaccaacca ccccattaaa agtagcaggt
    50341 gatcaaacaa ttgttggtgt aaaagatggt attccattaa tccaagatag tgaagggaat
    50401 ttggtaaagg atttgtcgat tcctgtaaag aaacttccaa gtggcaatat tgaaatcaaa
    50461 acagcagatg gaaaaacaaa agtcttacca aagactggtg aagaaataca tgttgcactt
    50521 tctgttctag gaggagtgtt gacaagtatt gctggatttg ttggatataa aagaaagaga
    50581 aaaggaatag aaaatgaggg taattgaatg gactattttt cagaaaaaca agcttatcgt
    50641 tgtcaatcgt acgtactagt aaaaacatac tagaaggagt agcttatgaa aaaacgacaa
    50701 ctacggcgga aagaaaaagt ttatacagag aaagtaccga agcaaaagaa aatccattca
    50761 aaaaaagcag tgaaatggat ttggtgtttg gttttatttc tttgtttttc agggggcttg
    50821 gcattttttc aatccatgaa aacgaaggtt caagtgtcgt ttttgaaaga tgaaatccaa
    50881 caattacaaa agaaagaagt acaaagtcgg tcagaattaa cgtacacacc tgaaattgaa
    50941 tcctttatga atcgttttgt tgctttgtat atgaatacat tcgataatca tgaacaagaa
    51001 caacaacgtc aagaaacatt aaaaaaagag ttttatgcac aaaactttat tcaagaacca
    51061 ggaagtgttt caggtgttcg aaaattaact gctgcttcgt ttattggatt aaaagaaatt
    51121 gaaaccattc caactgctag ttataaagta acttatgata ttcgctcgat gaatccagag
    51181 agtaagaaag aaacaagtgt gacaatcaca caagtactca atcttccctt ttctatttca
    51241 aacaagggct gtcgtattat tgcttatcct tattttacgg cactaccaaa gaatacagaa
    51301 aaacaacgaa tgattactta tgatgacaca ttatacgaaa cggttgatgc gtcggaagcg
    51361 aaagatgttg aaggatttgt ggaagatttc ttagataagt atgcgaaaaa caatgcaaaa
    51421 gatatgtcat acatgatgaa agaacctgaa ggactcaatc aaacagctaa agttgatcaa
    51481 gtagagatga aagtattgcg ttataaagaa acgaaaaaac cttttattgt aaaagcaacg
    51541 gtcgtctttc gagatggtga tacgtcactt ttacaaaaag aacaaatgac gattgtcatt
    51601 acgaaaaaaa caaatcagta ttatgttgaa aaattaacac ataattggtt ggataggaaa
    51661 ggagaagaac ggaaatgaca ctgaagggaa ttgtagattt tatattaacg caaggtggct
    51721 attttttaat aatggtggtt gtttatctgg gattgcgaaa ttttatgaaa tcaaaagtag
    51781 gaaatgcatt aatatctatc gcagcaggtg ccgcagttta tttcttctta aatgatccaa
    51841 cacgtgtatt tgatgcgttt ggtaaaatca ttgaaaaatt atttatggat taggaggata
    51901 gtgaagtgga ttgggaacct tatgattatt cgattgttta tgcggaacct tatcgcgtac
    51961 aacagattac aagcaattgg cgtcttccat ttccagttgc attagtcaat gcagcaactt
    52021 ttttgttggt cgtaatcttt gaatatttat ttttacgttc atttattggt tgggtcattt
    52081 ctttttttcc accagcagga gttgtttttt atataggact cccctattta tgtgtgttag
    52141 cactggcaaa actaaaacct gatggaaaaa aagtgcattt ttatttatgg gattggtttt
    52201 gttatatgat tcgtatgatg aatggtgatt gtgtgtatta taactgggac aaggtatcaa
    52261 acaatgcatt ggaagaatta ctttttgtga ataagtatgt ttatttagag gattagaaaa
    52321 agggacaatc aactggttgt tcctttttta ttgggaggtg aaattcattg gtgcttgtaa
    52381 aagaaccagt aaaagcattc aagaaaaatt gtttgttaaa tggagaggat tgtatctggg
    52441 cctactatca tgtttttcca cgaacaattt caaaaaacac accaaaaaag acacaggaaa
    52501 taaaagaaat gatggctcgt ttactgttgc ttttagcaga ttatgaagat gtggagttgg
    52561 tgatgtatcc acgaacaatg aatttacgga cgaagtttga cacattagga aagggatttt
    52621 ctcccgatag tcaagcaatt ggtgcgtatt atgcaaaaga aacagtgaca ttgttggaac
    52681 gagaaggtca agtctatcgt ccttcattta ttttaggaat caaagtcaaa gaaaaagcaa
    52741 cggtggagag ttttcatgat gtaataaatc taatctggtt agatttagca ggaagtttag
    52801 cacgcttatt tggattagaa gtagatgatt tggaaacttt gttttctgaa agtgatcctt
    52861 atgtaaaaga agtgacacaa ttactttata gcttttctat tcgtccctta gtaaaaaaag
    52921 agctgttgta tctcaatcgt ctgcaatata ttcgaggaat ggctcacaaa gtagaagaac
    52981 aaaataattg ggaagtactg aaagacaatc aaggaacgta tgtacgtata ccgaaggaac
    53041 ataaaggcct tcttcaatta gaagatgagt tagggagtag ttatttagca ttgttgccta
    53101 ttggggaaac acctgaaaat atgagaaatt gtgatctatt tcaatttgct caggatcttt
    53161 ctttcccagc agaattgcga atgaaaattc actatccacg cttgaaagga cagggaggta
    53221 ttggtttaaa actgaattgg ctatcggaac ggttcaaaac agagcataag gaattggttc
    53281 aaaatgatga agaacctagt gaacgcttat taactgttcg aggattagta aaacatttaa
    53341 agcaacgagt agataatggg caacctgtcg tcgattggat cgcatgtttt attgtatacg
    53401 gtcaaacggt tgaagaagtt cgtcaaaata gtgcaacggt tattcaacaa cttcatacga
    53461 ttatccatat ccaccgtgca aaaaatgatc aacgagaatt gttctataaa tgtttattag
    53521 ggcaaccatt gggacggcag ttacattgga agcaccgaac aactgtagaa gcagttggcg
    53581 aatggttgtt ttcagcagta tcagaattag gtatggaatc cggctggtat attggtcggc
    53641 aagatacatt aggggatggt ggttctcgag gagaaaaaac accattagaa gaattaattt
    53701 atgcgtcaaa tcgttttgtc tttttgaatc ttctagccat tgcggaagga atcaaaggtg
    53761 cgttgtttga tgcgcctcat gtagcagtaa ctggaaaaac cggtaaaggg aagacctttt
    53821 tagttggctt gctctttttg tatagttcgt ttatgaatgt acaaagttta tttgtggatc
    53881 ccaaaggaga aaagcgcaaa tggtttacga aactcattca agacccgtat tatcagaaac
    53941 attacccttt gtttgtagaa catttgcaaa aaatgagtta tgtcacgtta gatgctacaa
    54001 atccccgtaa ttatggtgta ttagatccaa ttgtttgttt atcccgagta gatgcgaaac
    54061 aagtagccca ggatatgatt gatgagttaa gtccgttagg taccaatcac cttttaaaag
    54121 gggcggtatt aaagggaatc caagaagttt tagttcaaaa agaagccgga caacaagttg
    54181 gcttgatgca tgtggtcgac tatttagaac aaatggaaca aaaagaggtt cgagaatatg
    54241 gtgagttttt acgcttgacg gtagaagatt cgattttacg tttaggattt tcttatggag
    54301 aaaacccggg attagacttt aatgccaaaa caacgatttt agagatccaa gatttgaaat
    54361 taccaaatga caatgtccga ccagaactat atacagatgc ggatcgaaag tctttgtgtt
    54421 tgatgattag tttaggtcgt ttttgtgaaa tgtttggaaa acgagatagt agtaagaaaa
    54481 cagcgattta ttttacagaa gcatgggtat ttaataattc gaacgcagga cgtagtatta
    54541 ttgcagcaat ggcacgtgtg gggcgttccc agatgaatca attagtgtta gatacacaat
    54601 ttattggtga cttaggttca gataaagaaa aagggaattt tggtgtcgtc tttgcttttg
    54661 atgaagacag tgagcgagaa aagattttga atcatttacg tttggaagta aatgaagcga
    54721 acttagctga aatgagccac atgattaaag gacagtgttg gatgttagat ccctatggac
    54781 gtgtaggaaa actcaatgta cacagtttgt ttgaagaaat gaccgctgca ttacaaacaa
    54841 cggaaaaaac aagtcactct caagtagaag aacaggatac gttaatcatg caatagaaat
    54901 gaggtgaaac aatggcttat ataaagcata aggaaaagaa atggtgcgtt ttgttttttt
    54961 taacgattgg attcggactg ctttttgttg gtggattggt gtatgcggca gaaaagcagg
    55021 tggatcaatc gatctatgag attgggaaat ttcatattga taccttttct tcttatttat
    55081 ctgatagtga attttcatta ggcaaaatgt tatttggggc aaatggcaca gattttctaa
    55141 aaatgatgac gaatatgttc tttagtttaa gtaaattgat ttggcaaggc cttgattttg
    55201 tcattgagaa gctctatgaa ggagctgcaa tgaacgagtt aattcaccag tttttcactt
    55261 tttcggatac tatttattca aaaatatacg atcctattgg tgcggggatt gtcgtcttgt
    55321 atgtgttata tctatttact cttcgtatat ttagagggaa acattacgca aaaatggtgt
    55381 ttattcgatt tctcttcgtt gtcatttttt caatggtttg gtttggctat ggtagtaacg
    55441 tacctagtaa aggagaagct tttaccaaag ggttaaatga tttgtccgtg gaggtagaag
    55501 gctttatttt ttctgctaca aatagtctag atgaattggc gacaaaagat gtcaatggtg
    55561 ttttagtgcc aacgacacaa aaggaagcca ttcaaaaagt gcgccaactt tattataaag
    55621 cggctgttgt tgatccgtat atattgttaa attatgggac aacaaattta gaagaattgt
    55681 atcaagcaga gattgaacca caagaatttc tagccaagga agcgtcaagt gaagaattat
    55741 ctgatattga gacaaaagtg accactgctg caggagaaga tagagggaaa aagaaggctt
    55801 atcgtgtcta tattcaacca actaaagctg tttataaagc agtcgttggt tctatggtgc
    55861 cattgcttaa tctaagtatt ggattaccac ttgtagtgat tggcatgatt cgttttatct
    55921 ttcaaatgtt ggtgttgtgt ttattacttg tgattccttt ttcattactc gcttcttttg
    55981 ttccagtatt tgattatatg ctcatgaata ccttaaagtc ctttttgggc ttgatgtttc
    56041 aaaaatcttt ttacagtgtg attattttgg tggcattttt gatctataac atagtagacg
    56101 atttaattcc aatgaatact gtttttggtt ttttaggaaa tatgtttgtc aaagcactcc
    56161 tatcaatttt actcattgta aaacggaaag atttattaaa gaaactaggg ttaggagctg
    56221 cagatcaaac tataaacaac acgaaaaaca tagcaagtca ttctttgtct caaatgaaac
    56281 aactgcctgg tcaactatca actgctggac aaaatttggc aatcaaaggt gcaggattag
    56341 cagggaatgt gtatcgagca acgaatccac tcgcttctgc agcgatacat ggatttcaaa
    56401 agtttcaaca aaaacgtaca ccacaagaat cggtaaaagg gaggcaagtg gttaatccct
    56461 ttgaactagg tgggcgttca aatcaagcct tgccttatag tggtcgtcat gttcgttatc
    56521 atggggtaga gcctgaaatg tcttctacca aatcgaaaac agagtggaat tctggtcttt
    56581 caaatggttt gattccaaat tcgtccatga attcagtaag accaaaacaa caggtacaat
    56641 cattggcaca attgagtaag caacaaggga ataatcaaag aaaaccattg ttaaataaag
    56701 gtatcgcttt tgttggtcaa tcgattccgt tgccttctgg aaaagtaccc gtgccacaat
    56761 taacagctgc tggttctctt tcacaacaga ttcgccaagt gaaaaatcag gcgaaaaatg
    56821 ggagttatcc agcaatgcag cagttattga accaatactc tgttcctaat tcgtcggtag
    56881 ccactctatc aggaaatcgt tctgtgcaac aaccggggca acgttcgtct gaaagtaaac
    56941 cgtcgatttc cgcaccaaaa tcgttacaac ctgcattttc ttctttagat aagccaacag
    57001 agcaatcgga aaaaatagaa aaggatccta aaacactgcc gattttggac gcaaaaccag
    57061 gaactgattt tactttacca aaaggacgaa cagtccaaaa accattatcg aagaaaggat
    57121 gaggaagaaa tgaagaaagg gtgtctaggt tgtcttcttt tctttattct tccctttttt
    57181 ctattgccat tctttttttc aggagaactt tctgagcatg gaggagaagc tacaggtcta
    57241 gctgtcgctt ttaatgggga atataccgaa ggattaccga ttttttcaga gattaaagga
    57301 cgtggtccaa tcacagatga acatgcgcaa gcagcagttg gtgcagctgt aaagtatcag
    57361 ttattaccga gtgtgattct ttctcaatta ggctatgaat cagcttatgg acagtcacaa
    57421 tctggaagaa acgatacgaa cttttttggg attacctggt ttcctggttg tccctaccca
    57481 caaggttctg cacgtggaat tggtggttct gaaggtggtt tctatatgaa gtttccgaac
    57541 ttaaaagctt gttatgacta ttatggcttt atggtggcga gccaaagcaa ctttaatcaa
    57601 tgtgtgggca ataaagatcc tggaagttgt ttattgattc taggtcgtgg aggctatgcg
    57661 gcagcaggta ttaccgaagg gagtccgtat tatcgaggag caatgagtat cataacgtcc
    57721 tataacttaa cggaatatga tacttttgcg atcaagcatt ggaatagcct accaacaaaa
    57781 aaaacttcgc ttattgcagg aaaaagtaaa ggcaatgcga aggttttgga tcggatcatt
    57841 ggacgatccg taaataatgg ggaatgttat ggtggtacgg catggtatgt atctcaatta
    57901 ggtggcccac agttaatggg ttctggacac atgtttgcga tgttaatagg ggaagattat
    57961 aactggacaa cctatggttg gcaagtaatc atgaacccaa aaccaagtga tttacaagca
    58021 ggagatgtgg tgaattggca agcaggtggt gcattgtctc ctggaatcta tggtcacacc
    58081 ggaattataa cagatgtttc atatggcgga caacatttct ctagtgtgga acagaatgcc
    58141 gagcaaggac ggattatggc tcggtatcaa cgcacgtaca atcaaacaaa aattcgtagt
    58201 ctggttcgta aggtgaaata agaaaggcag tgactagaaa cgtgaaaaaa gggataattt
    58261 tagtatttag ttggttatgt ttgataggtc ttactggttg tcattggttt tcttctgaaa
    58321 aacaaaaaac acaattgaga acgacagaag aaacaatcga agcagtaaaa gaaacaagtg
    58381 gaactcttca aagtactgaa agtaacagtc aaattggttc attagaagac gagacagcgc
    58441 aacaaatgca aatagatgaa atgacaaaaa atttcttaaa agattttgct agaaaatgga
    58501 gtaatttcac agatgtttat aaacgcaatc aagctgtgag ggactatatg acagatcgtt
    58561 gtattaaaga caatagtatt gatgtagacc cgcatgtaca aatgaaaaca actgggaaac
    58621 tttaccaggt gacacaagat atagagaatc cggatcaata tttgttattt ggagaagaaa
    58681 caatgaataa ggttactcaa tttgtat
//
LOCUS       DACBYO010000007        57508 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.007, whole genome shotgun sequence.
ACCESSION   DACBYO010000007 DACBYO010000000
VERSION     DACBYO010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.007"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(577..1080)
                     /locus_tag="IVD26_000395"
     CDS             complement(577..1080)
                     /locus_tag="IVD26_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP6078400.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1439..2464
                     /locus_tag="IVD26_000396"
     CDS             1439..2464
                     /locus_tag="IVD26_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP6078401.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2787..3665
                     /locus_tag="IVD26_000397"
     CDS             2787..3665
                     /locus_tag="IVD26_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078402.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            4141..4257
                     /locus_tag="IVD26_000398"
     CDS             4141..4257
                     /locus_tag="IVD26_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAP6078403.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            5185..5523
                     /locus_tag="IVD26_000399"
     CDS             5185..5523
                     /locus_tag="IVD26_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078404.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            5617..5847
                     /locus_tag="IVD26_000400"
     CDS             5617..5847
                     /locus_tag="IVD26_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078405.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            6247..6618
                     /locus_tag="IVD26_000401"
     CDS             6247..6618
                     /locus_tag="IVD26_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAP6078406.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(6892..7584)
                     /locus_tag="IVD26_000402"
     CDS             complement(6892..7584)
                     /locus_tag="IVD26_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP6078407.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(7587..8372)
                     /locus_tag="IVD26_000403"
     CDS             complement(7587..8372)
                     /locus_tag="IVD26_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP6078408.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            8609..10009
                     /gene="lacG"
                     /locus_tag="IVD26_000404"
     CDS             8609..10009
                     /gene="lacG"
                     /locus_tag="IVD26_000404"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAP6078409.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            10034..10351
                     /locus_tag="IVD26_000405"
     CDS             10034..10351
                     /locus_tag="IVD26_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP6078410.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            10364..12037
                     /locus_tag="IVD26_000406"
     CDS             10364..12037
                     /locus_tag="IVD26_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6078411.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            12051..13682
                     /locus_tag="IVD26_000407"
     CDS             12051..13682
                     /locus_tag="IVD26_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAP6078412.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(14173..15738)
                     /gene="guaA"
                     /locus_tag="IVD26_000408"
     CDS             complement(14173..15738)
                     /gene="guaA"
                     /locus_tag="IVD26_000408"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAP6078413.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(15797..16720)
                     /locus_tag="IVD26_000409"
     CDS             complement(15797..16720)
                     /locus_tag="IVD26_000409"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAP6078414.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            16916..17521
                     /locus_tag="IVD26_000410"
     CDS             16916..17521
                     /locus_tag="IVD26_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6078415.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            17829..18845
                     /locus_tag="IVD26_000411"
     CDS             17829..18845
                     /locus_tag="IVD26_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6078416.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            18986..20287
                     /locus_tag="IVD26_000412"
     CDS             18986..20287
                     /locus_tag="IVD26_000412"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAP6078417.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            20333..20995
                     /gene="deoC"
                     /locus_tag="IVD26_000413"
     CDS             20333..20995
                     /gene="deoC"
                     /locus_tag="IVD26_000413"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAP6078418.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            21016..21414
                     /locus_tag="IVD26_000414"
     CDS             21016..21414
                     /locus_tag="IVD26_000414"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAP6078419.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            21480..22562
                     /locus_tag="IVD26_000415"
     CDS             21480..22562
                     /locus_tag="IVD26_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6078420.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            22774..24336
                     /locus_tag="IVD26_000416"
     CDS             22774..24336
                     /locus_tag="IVD26_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6078421.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            24329..25462
                     /locus_tag="IVD26_000417"
     CDS             24329..25462
                     /locus_tag="IVD26_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6078422.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            25462..26418
                     /locus_tag="IVD26_000418"
     CDS             25462..26418
                     /locus_tag="IVD26_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6078423.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            26517..27683
                     /gene="deoB"
                     /locus_tag="IVD26_000419"
     CDS             26517..27683
                     /gene="deoB"
                     /locus_tag="IVD26_000419"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAP6078424.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            27707..28525
                     /locus_tag="IVD26_000420"
     CDS             27707..28525
                     /locus_tag="IVD26_000420"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP6078425.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            28542..29249
                     /gene="deoD"
                     /locus_tag="IVD26_000421"
     CDS             28542..29249
                     /gene="deoD"
                     /locus_tag="IVD26_000421"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP6078426.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(29535..30221)
                     /gene="gpmA"
                     /locus_tag="IVD26_000422"
     CDS             complement(29535..30221)
                     /gene="gpmA"
                     /locus_tag="IVD26_000422"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP6078427.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(30393..30974)
                     /locus_tag="IVD26_000423"
     CDS             complement(30393..30974)
                     /locus_tag="IVD26_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6078428.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(31107..31790)
                     /gene="rpiA"
                     /locus_tag="IVD26_000424"
     CDS             complement(31107..31790)
                     /gene="rpiA"
                     /locus_tag="IVD26_000424"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAP6078429.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            32109..32522
                     /gene="rpsL"
                     /locus_tag="IVD26_000425"
     CDS             32109..32522
                     /gene="rpsL"
                     /locus_tag="IVD26_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAP6078430.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            32606..33076
                     /gene="rpsG"
                     /locus_tag="IVD26_000426"
     CDS             32606..33076
                     /gene="rpsG"
                     /locus_tag="IVD26_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAP6078431.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            33170..35257
                     /gene="fusA"
                     /locus_tag="IVD26_000427"
     CDS             33170..35257
                     /gene="fusA"
                     /locus_tag="IVD26_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP6078432.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            35429..36616
                     /gene="tuf"
                     /locus_tag="IVD26_000428"
     CDS             35429..36616
                     /gene="tuf"
                     /locus_tag="IVD26_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP6078433.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            37023..37331
                     /gene="rpsJ"
                     /locus_tag="IVD26_000429"
     CDS             37023..37331
                     /gene="rpsJ"
                     /locus_tag="IVD26_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAP6078434.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHEYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            37362..37991
                     /gene="rplC"
                     /locus_tag="IVD26_000430"
     CDS             37362..37991
                     /gene="rplC"
                     /locus_tag="IVD26_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAP6078435.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            38019..38642
                     /gene="rplD"
                     /locus_tag="IVD26_000431"
     CDS             38019..38642
                     /gene="rplD"
                     /locus_tag="IVD26_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAP6078436.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            38642..38932
                     /gene="rplW"
                     /locus_tag="IVD26_000432"
     CDS             38642..38932
                     /gene="rplW"
                     /locus_tag="IVD26_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAP6078437.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            38971..39804
                     /gene="rplB"
                     /locus_tag="IVD26_000433"
     CDS             38971..39804
                     /gene="rplB"
                     /locus_tag="IVD26_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAP6078438.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            39847..40125
                     /gene="rpsS"
                     /locus_tag="IVD26_000434"
     CDS             39847..40125
                     /gene="rpsS"
                     /locus_tag="IVD26_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAP6078439.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            40148..40495
                     /gene="rplV"
                     /locus_tag="IVD26_000435"
     CDS             40148..40495
                     /gene="rplV"
                     /locus_tag="IVD26_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAP6078440.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            40509..41165
                     /gene="rpsC"
                     /locus_tag="IVD26_000436"
     CDS             40509..41165
                     /gene="rpsC"
                     /locus_tag="IVD26_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAP6078441.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            41168..41602
                     /gene="rplP"
                     /locus_tag="IVD26_000437"
     CDS             41168..41602
                     /gene="rplP"
                     /locus_tag="IVD26_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAP6078442.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            41592..41780
                     /gene="rpmC"
                     /locus_tag="IVD26_000438"
     CDS             41592..41780
                     /gene="rpmC"
                     /locus_tag="IVD26_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAP6078443.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            41805..42071
                     /gene="rpsQ"
                     /locus_tag="IVD26_000439"
     CDS             41805..42071
                     /gene="rpsQ"
                     /locus_tag="IVD26_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAP6078444.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            42129..42497
                     /gene="rplN"
                     /locus_tag="IVD26_000440"
     CDS             42129..42497
                     /gene="rplN"
                     /locus_tag="IVD26_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAP6078445.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            42534..42842
                     /gene="rplX"
                     /locus_tag="IVD26_000441"
     CDS             42534..42842
                     /gene="rplX"
                     /locus_tag="IVD26_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAP6078446.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            42870..43409
                     /gene="rplE"
                     /locus_tag="IVD26_000442"
     CDS             42870..43409
                     /gene="rplE"
                     /locus_tag="IVD26_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAP6078447.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            43428..43613
                     /locus_tag="IVD26_000443"
     CDS             43428..43613
                     /locus_tag="IVD26_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAP6078448.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            43649..44047
                     /gene="rpsH"
                     /locus_tag="IVD26_000444"
     CDS             43649..44047
                     /gene="rpsH"
                     /locus_tag="IVD26_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAP6078449.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            44079..44615
                     /gene="rplF"
                     /locus_tag="IVD26_000445"
     CDS             44079..44615
                     /gene="rplF"
                     /locus_tag="IVD26_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAP6078450.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            44776..45132
                     /gene="rplR"
                     /locus_tag="IVD26_000446"
     CDS             44776..45132
                     /gene="rplR"
                     /locus_tag="IVD26_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAP6078451.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            45153..45653
                     /gene="rpsE"
                     /locus_tag="IVD26_000447"
     CDS             45153..45653
                     /gene="rpsE"
                     /locus_tag="IVD26_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAP6078452.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            45668..45847
                     /gene="rpmD"
                     /locus_tag="IVD26_000448"
     CDS             45668..45847
                     /gene="rpmD"
                     /locus_tag="IVD26_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAP6078453.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            45891..46331
                     /gene="rplO"
                     /locus_tag="IVD26_000449"
     CDS             45891..46331
                     /gene="rplO"
                     /locus_tag="IVD26_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAP6078454.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            46331..47626
                     /gene="secY"
                     /locus_tag="IVD26_000450"
     CDS             46331..47626
                     /gene="secY"
                     /locus_tag="IVD26_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAP6078455.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            47688..48335
                     /locus_tag="IVD26_000451"
     CDS             47688..48335
                     /locus_tag="IVD26_000451"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAP6078456.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            48526..48744
                     /gene="infA"
                     /locus_tag="IVD26_000452"
     CDS             48526..48744
                     /gene="infA"
                     /locus_tag="IVD26_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAP6078457.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            48777..48893
                     /gene="rpmJ"
                     /locus_tag="IVD26_000453"
     CDS             48777..48893
                     /gene="rpmJ"
                     /locus_tag="IVD26_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAP6078458.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            48911..49276
                     /gene="rpsM"
                     /locus_tag="IVD26_000454"
     CDS             48911..49276
                     /gene="rpsM"
                     /locus_tag="IVD26_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAP6078459.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            49304..49693
                     /gene="rpsK"
                     /locus_tag="IVD26_000455"
     CDS             49304..49693
                     /gene="rpsK"
                     /locus_tag="IVD26_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAP6078460.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            49773..50711
                     /locus_tag="IVD26_000456"
     CDS             49773..50711
                     /locus_tag="IVD26_000456"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAP6078461.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            50739..51119
                     /gene="rplQ"
                     /locus_tag="IVD26_000457"
     CDS             50739..51119
                     /gene="rplQ"
                     /locus_tag="IVD26_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAP6078462.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            51391..52230
                     /locus_tag="IVD26_000458"
     CDS             51391..52230
                     /locus_tag="IVD26_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP6078463.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            52206..53075
                     /locus_tag="IVD26_000459"
     CDS             52206..53075
                     /locus_tag="IVD26_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP6078464.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            53065..53862
                     /locus_tag="IVD26_000460"
     CDS             53065..53862
                     /locus_tag="IVD26_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAP6078465.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            54065..54811
                     /gene="truA"
                     /locus_tag="IVD26_000461"
     CDS             54065..54811
                     /gene="truA"
                     /locus_tag="IVD26_000461"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP6078466.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            55476..55713
                     /locus_tag="IVD26_000462"
                     /pseudo
     CDS             55476..55713
                     /locus_tag="IVD26_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(55857..56633)
                     /locus_tag="IVD26_000463"
     CDS             complement(55857..56633)
                     /locus_tag="IVD26_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP6078467.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            56756..57163
                     /locus_tag="IVD26_000464"
     CDS             56756..57163
                     /locus_tag="IVD26_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAP6078468.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        18431 a        10241 c        12224 g        16612 t
ORIGIN      
        1 atattaacgt gttttcaaac agtataaaac ggtgtggttt ttggaataaa aaaataacat
       61 atctcatttt acacttttgt tattttatac ttaaaaaata acgacacaga aaataccgtg
      121 tctcagattt ctctactact tctaaaaact actgtttttt tcctttgaaa tgccttcaaa
      181 aagtaggatc aggcagaata tactggcaga atcaaggaga agggagccta aataaggaga
      241 aaaaccatag aaaatataaa gtaattactt ataaaacaag ctttttatag aaaaataata
      301 tacctgagta gggtataaat taagacggaa ttcctttcta gattgagata ttgactagga
      361 agaatgttaa gattttaagc ctttaagcta aaaaaaaacc ctttttgtta aataagggga
      421 atatagcctg tcagtttcaa actgcaagtc gtcctgctgc aataatatag tagattagag
      481 atgaaaatag atttttttaa accaatgact gaataaaaag accgtcatag atacacattg
      541 gaatgtgtct attacggtct ttttttacga acgattttat tgaagacgga cagttcgggt
      601 caaaaataaa aaagctacga tcagaaataa gaataaaatg tatcccaaaa taatggctag
      661 acggtctaac ttatttgtcg atagatgttt gtttagaagt tgataggccc ataaacctat
      721 cagtcctcct gttgtattag ttatcaaatc agtgatgtcc gctacgccaa taccgaatag
      781 gaattgaatc aattctgcca agaagcttac aaggaaaata atccctaatt ttttagaaaa
      841 agaaagtctc ttgaaattga cattcaaaag caccccaaaa ggaaaaaaga caatcaagtt
      901 ataagtggtc tcacgtaata ccgtcgtatt ttcaaaagaa aaagtagaaa aagggacgag
      961 attgacattg ctgtaagaat aagtgagaaa ttgtggaaga ttaaatgata gcttgaataa
     1021 aatcaaccat aatagaaaga ataaataaat ccctaataaa aattttgata cataccgcat
     1081 agacatctcc tccatttaaa aagtatacca tcgaaaaccg ctgaaaaatc ataaaaaagt
     1141 atgaagttta aggaccaacg tagttatcgt acgaaaatta gaagcttttt tttgttggga
     1201 atccggtttc tttaacaaag ctaagatagc gagttgcttg gaaaagttgc tatctttttt
     1261 ctgtcaaaac gactcggaat gttcgttttt tgttctaatt tctccaagtt gtttactttt
     1321 tgatactaag tttatgaaaa atcaagaaat agttgttata ctaggtaatg ctgacaaacg
     1381 ggattggcat ttcatcttgg ttcagctttt tttccaatta ctaggaagga gggatagatt
     1441 gttcaagact tattttcgtt tcaataaaat acaagataat ccttttcgta tcatgaatct
     1501 gatgctactt atctttattg tattatggtt aggttacata aatcatgatt ttttgatttc
     1561 aagtttttca tcattaggga tctttacttt tttctattat caaaacatac cgatgaaata
     1621 tttgctgaaa cgtatgtttc tgatcggttg cggactgttg gttgctttcg ttttggggat
     1681 cttatcgact tatgttttat ggcttgaacc atttgccgta gctttggttg ctttttccag
     1741 cagattcgtg ttgcgattat tccatatttc taaaccaggt ggcttgtttt ttgcgatgct
     1801 ttctgccatg ggaacgagca tgcagctgcc aatcgctcaa ttaccgatcg tctcacttta
     1861 tttttttatg ggtgtcgttt ttgccctgat tgcggcagtg attacaaaat tactggattc
     1921 acggcctgag cagacaattg aaaaagcaac tttaaaagaa agatttcacg aagagccttt
     1981 agtgatcatt gattctgttt tctacagcgc tgccttattt ctttccgttt atgtcagtca
     2041 cggcttgaat ctgcataatc cttattggtt gaccttgtca tgtgcatcga ttttgctagc
     2101 agaaaacttg gatgcgatga agcatcgaca agtccaatat ctgattggat cgatgggtgg
     2161 gttatgtgtg tcggcattct tgtcatttgt gccgtttacg cagttgcaga ccatttttct
     2221 gatcactttt ctatatggaa tcgcacaatt tctagttgct agaaattatg cagttgctaa
     2281 tatttttctt aatccgatgg cgttgatgct atctacactt attcgtggag catacttgat
     2341 ttctttgatc gaatatcgtt ttttagggat cgtcatagga agtttcatcg gtttaggtgt
     2401 tgcgtgggta atgacggttg gtttgcaaca ttatttaacg gttgttcgtc aaaaattaga
     2461 atagaaggac aaatatatgt gccaaaagag gttatgacaa gatttttgtc acaacctcta
     2521 attcaaggtg ttcaaaagcc agattctcag cattaagtca aattcacaca aaaatgtgga
     2581 aaggaacttt caaaaaaatt ttatatttat tctatcaaaa aattttgttt atgatggtaa
     2641 ctgaataaac tttcctgaga tggtcaatgc tttccttgaa agtcttacag atattctttc
     2701 ttcatagaaa gtttaagttt tatagttagt gtacaataaa agtatgttta taccatatgg
     2761 tgtccggata atcagtcatt taaacaatga ggttcaaaga tatgaaaagg ggaaatttga
     2821 tgaagaaaat aagcaatgaa atccaaattc tggcagaaac tttaactctt cccaaagtcg
     2881 ttatagagca aatgattgta caagcaaaaa acatccttga tgaggtgttt gagcaatata
     2941 gtcatgaact aatggatcct aataaagcaa aggcgactgc aaagaaaata gacaaagtct
     3001 atgaagagga accttttgca gcattagcta tttatctata tgcagcttct caaagttgga
     3061 aaaaaattta tcaaccattg aagattccaa gaactatcta tttggcaaca atgaatgctt
     3121 ttactagatt tattcatgaa catttccaag taacaggaag ctatcgcttt gaccgtggtt
     3181 tttggatttg gcattacact agtggcttga tctttcggat tggtgaattg gagtacgaaa
     3241 tgacatattt tccgaaaggg tacacggatc taagattaga aggaaagcag tgcctttctc
     3301 ttcatattcc ttccgatgca gatttatctc agaataagat aagagatagt tacgaaagtg
     3361 ccattcgttt ttttgaactt tattttcctg attaccatta ccaagtgatg tacacagata
     3421 cttggttact atcacccaat cttactaaat ggttgaaaaa agagtcaaaa atctgtcttt
     3481 ttgcagccga ttatcgatta ttatcagttg atgaacagga cgatagtgga gtcccttgga
     3541 tctttggacg agtagatgcc caaatacatg attatccaga aagtacgagt ttacagcgac
     3601 aagcaaaaga gcaattgctt gcaggcgagc acattggctc tggcttaggt attcttactt
     3661 cataagttta gtacttcgaa atagtttaaa agagcgtgag acaaaagtaa agaacacttt
     3721 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cggaaataag
     3781 ctgaaattca caaaaatttg aaaagcaatt ttcgtgaatt tcttcttatt tcttggagtt
     3841 aaacgcttct gtcccagcct cttttttagt gttctatcga acacacagta cgttcaatag
     3901 gtaaactagc tataacaata gatattaaag ttaacggaca agagggcctt ttttaggtag
     3961 ctaaaacgta ataatgaaaa tttatttcca gagataggag tcaatcagct agtctgatcg
     4021 actgttttaa caagttgact ttcattttaa cttttgatac catttaaaac acaaatcgta
     4081 attgtttcga tttgtgtttt ttagcatgac tacaatcaaa gaagaaagtg ggtcgtccat
     4141 atggaaaaaa cagatatctc aagtgcatac cgccgcttga aaagcccaaa tatcaaaaca
     4201 cgaaaacgtg cgctgaagat catcaaagat gtgaaacgga atagtgggaa aaggtaagaa
     4261 gaaggaaact taattaaaaa aatagccgaa aaacgttttt cggctatttt caataatcgg
     4321 tttttgtgta aggtttccga aagaactgct gttgattttc catttttaac atatgataaa
     4381 ttggtagaat ctttcttttc aaattgatac cattccctaa ttccagttat atagttaact
     4441 acagaaccac aaagcacgta cgtttataaa agtattatct gtagttattt ttcaattccc
     4501 tttcaacctc ttattttgac cagtagtatt gatcacttta ccttttaaca cctttgttcg
     4561 tttttgaaac atttttagtc aagaatggaa acgtaactac ataatcaaag gttttgcgaa
     4621 atatttcatg aaatatttca tgtagaagcg agcaatacgg ttgcaaataa ccattatcgt
     4681 ttaataagca gttacgaaag ctcccaatat ctctaacgtt cagctcactc catttctttt
     4741 cttcaaaaaa atcagtgatt cgtatctctt tctatttgtc gaaaaagtta actttaaaaa
     4801 gtaacgccga aaaaatatgc aaaaaaataa aaaagcagtt actattgcta gaataacatc
     4861 aaggaataat aagttttggt tttcagataa tagtcgataa gttgtgtatt ggaattttag
     4921 atacagtaat aaagtatttt tcatgaaatt ttgtgagaat cactattaca agtatcttta
     4981 ataaaattaa tggttaagga ggaacttaaa gtagaatgta aatgaatagt tgtagtcagt
     5041 cgattgtgat actagactca aagttgcagg aataagtttt tcaatttgtg attggaagat
     5101 aaaaaatgaa aaagaagggc ttttttttat actttgttga ttgtagtgtt tattttccct
     5161 ctgtttagcc aagtaacatt ttctatgact caaccagttt caagtgagga acatgataac
     5221 ctttttcgtg ctacagaaga gtttaagaaa tatcaggaaa atattgttcc ggagactcca
     5281 ttagctagtg agccaattac tgatattgat ggaaaccaaa taggatggta tatacagtac
     5341 gaagttatgg tggtaaataa tgactcaata gtaaaaaata cagtaggctt agagctaaca
     5401 ccgattgaaa aggtgagttc attgttaacg tatatttata ctgatgaaag tgacgagact
     5461 gagatcattt taacggatta ctcaaaaatt gctactgata aaaagtatat attgtggatg
     5521 tagacactag tgaaatactt tatgatatag aaattgatga aaatttacta gatgtagcac
     5581 aagaaatcga tcatcaaaag caggaagcta ttcgatatgc tggtagaaaa gggaaaagaa
     5641 aatatttatt acgtgaatgt agcaaaagtt agagaagatg aaaatgagtg gaaagaattc
     5701 aagagtcgct actcaattaa ctcgactccg acatttacag tttacagaga aggatcgata
     5761 gaaaaaactg ttttttggac taaagaaagt ggaatgtctt tagctgaagt agaagagttt
     5821 ttggattatg ttagtatgca acagtaaggg agttcttatt atgaaaaatt ttgacacata
     5881 ttatgttatt gttttttcga tatctttgct gttaatatta ctaactttaa tgcagtataa
     5941 agagtatcca gagtatttta ttttaacttt tgtatattta gtaagtagct acacacttct
     6001 atataaattc agaagttctt ctagagtttc taaagtttgt ttcttaatta gcttattgat
     6061 tctataatat ttttgattta tataggaaat taaaaatatt atagaatcaa cactcagaga
     6121 acgggttggt ttttaataga tttaataagt actgataatg aaatttctcc tggttgggaa
     6181 aacgaagttg gttaccctgt agaagaattt tttcaagatt actttgcgga gtatgccgat
     6241 aggataatga gagattacgt aacagataaa actcaagaag tcatcaatca atcccagtca
     6301 ttaaatgaat tatctgataa ggcgaaagaa gaagcagttg ccattatttc ttcagggatt
     6361 agtgactata ttgatatgag tggtgaaatc aattatggcg ataaagacaa aattgtacgc
     6421 atgataaaag cttttatcaa aacttttgat gtgaaggcag atcttaagtt taatgatact
     6481 tacctagtag gaaaattaat taatatcctt gggacagaga aagatacgga aacgtttatt
     6541 tcctctttgt ctatgttgtt tacagataag catttttcaa ctcagcttgg tggagaggaa
     6601 ctagtggaaa tcttttaacc attacgccca gcattaataa aagtatatca aaaaagtact
     6661 cctgatgatt tttaagattg gtttgagaaa taatgtgaaa acactatttt taatgttaat
     6721 tatagataga gatgaacgcg tcatatggtt aaaagaatga aaaagtcaaa gatacactgc
     6781 tatatttcac taaggatata gcagtgtatc tttcatgtcg tttcactggc agttttttat
     6841 aaaaggaggt gtgcatttca gttgcttttc tttggtagtt agttgaatcg tttaagaatt
     6901 aacggatgtg gcagacaggt gctctgtcca aaaaccagta aaatctttga tggttccatc
     6961 tttatttagc tgtgcctgtt caaatactgt tttgttttta ccgaatggat caattgcaat
     7021 aattgttccg atccccgcac gtttggcagc aagtaatcct gagtaagcat cttcgataac
     7081 aagacaatca gccggagcta agctcagttt gtctgccgct ttaagaaaaa tatccggttg
     7141 cggtttccca gggaaagagc cgtcgtcata gacaatcttg tcccagtcaa accagcgggc
     7201 taaatcgaaa atatcaaaat aaaaagcaac attctctttg acagtagccg tggcaatcgt
     7261 taatggaatc tgttggtcag tcagctggtc aagagtcgct tcaagccctt ttgtcaactg
     7321 aagctcgttt tcattttgca agcaaagcat acgataatag ctttcttttt cttctgacaa
     7381 tacggcgatc tcagaggcgg tcaaatgctc tgaaatgaaa tgtttcaaaa tctccgtatt
     7441 cgtccgacca tgaatatttt ttaaaatatc ctcgtctgat aaaccatctt ttgtatgatc
     7501 atgtatcata tgcagccaag cagcttcatg cagatgagag tccaaaaaca ttgttccgtt
     7561 gaaatcaaat ataatccctt tcatagttac gctcctatag tggtattttc ggttgaatca
     7621 gcaatttgca gatcgacata ttgtgcatag tgctcttgaa cctcccgcga gatctggcga
     7681 tccgtaatga gcagatcgaa atcatgcaaa ttataaaaca cataaaaatc atctcgattg
     7741 aattttttat tatcaacgag tagatatttc ttacgggaat tatttagagc gatctgctgt
     7801 gcttctcctt cttcggtact gtaagtagag atcgcttcgt tgtgaacgcc atttgaactg
     7861 ataaatgctt ttgtaaactt tagtcttctt aaattgtcgt tggtgatcgg tccgacaaat
     7921 gcgccggtat ttttccggaa atcaccgcca atcagtagaa tttctggtcc atctgcttga
     7981 gcaagaatat caaaaactgg ataattattt gtaatgatcc gaattttctt gttcagtaaa
     8041 tgcgtcgcca atagttcgat tgttgtacct ggtcctaaga aaatcgtttc tccctcgtga
     8101 atcaaggagg ctgctgtggc agcaatttct tttttttctt gaatctgcag agtggctttt
     8161 tcagtgtgag aaagttcttg atctaaagtg taggaaagac tttgagcccc tccatggaca
     8221 cgcagcagct tgcccgattt ttctaattca tctaaatctc tgcgaacggt catatcagaa
     8281 acatctaatt gattgatgat ttcattaacg gtaaggattc cttttttatt gaccatttct
     8341 acgatagtaa gcaatctttc ttttttcaac attgtcttca cctctaattt aaggataatc
     8401 tatcatataa acggacaaca gtcaatctaa ttcgaacaaa agtaaacatt tagggtggtt
     8461 tttatgtttg ttacaataga ttttattgct gttttctggt ttttatgatt atttgtgttt
     8521 gtttttgttg acaaatgttt tggatgcgtt tacaatgcaa tcagttagaa agagcgaaaa
     8581 ctgattatag atttgaggag agatgtacat gcttaaatta ccagaagatt ttatttttgg
     8641 cggagccaca gcagcctatc aggttgaagg agccactaag gaaggtggca aaggcgctgt
     8701 tgcttgggat gactttttag aggaacaagg gcgattcagt cccgatccgg caagtgattt
     8761 ttatcatcaa tatgcaaagg acattgaatt gtgtgaacgt tttggtgtaa atggtctaag
     8821 attatccatt gcttggagcc gcatttttcc tgatggagct gggaaaccaa atccagaagg
     8881 aatcgctttt tatcatcgtg tgttcgaaga atgtaagaaa agaaacgtaa cgccgtttgt
     8941 gacgttgcat cattttgata cccctaaacg tttgtttgac catggagatt ttttgaatcg
     9001 agaaacaata gaagcatttg tttcctatgc cattttttgt tttcatgaat tcaaagaagt
     9061 caaggtgtgg agtaccttta atgaaatcta tccagttgca accaatcaat atttgttagg
     9121 tgttttccca ccaggaatca aatatgattt tacaaagatc gtcgcctgtc ttcataatat
     9181 gatggttgct catgcccgtg tagtgaacta tttcaaagaa aacgaacttc cgggtgaaat
     9241 tggtgtagtt cactcattag agacgaaata tgcggcaaca gacgcgccgg aagataagca
     9301 tgctgccttt ttagacgatg cattgtcgat ccgtttctta ttagatgcta cctatttagg
     9361 ctattattca actgaaacct tgactgctct tgatgagata tgtgaagcaa atcaggccag
     9421 ctatcatttt cctgaagaag atttcgttga attgaaaaaa gcatccacgc gtaatgacta
     9481 cttagggatc aatcactacc aatgccattt tgtcaaagct tacgatggag aaaatgcaat
     9541 ccatcataac ggtacgggtg aaaaagggac ctctgtttat aaagtgaagg gaatcggaga
     9601 acgtatttat aaagaaggaa ttcctcgaac tgattgggac tggctgattt atccagaagg
     9661 tctatatgac ttgttgctgc gaattaaaag cgattaccca cattacaaca aaatctatat
     9721 cactgagaac gggatggggt ataaagatca gtttgaagat ggcattatta tggatcagcc
     9781 gagaatcgac tatttgagag tctatttgga atccttaagc aaggcgataa cagccggggt
     9841 aaatgtgaag gggtattttt tgtggtcgct tatggatctt ttctcatgga caaatgggta
     9901 taacaaaagg tatggcttgt tttatgttga ttttgaaacc cagaagcgtt acccaaaaga
     9961 atcagcttac tggtacaagt tggtcagtga aaccaaaacg attatttaat aagtgataat
    10021 ggaggaagaa aagatgaata aagaggaatt acaaatgctt ggttttgaga tcgttgcata
    10081 ttcaggcgac gctcgcagta cattattgaa attattgaaa gaagtaagac aaggaaactt
    10141 tgaacatgtt gattcggcgt tgaaagaagc cgacgaaaat ttaacccttg cacataattc
    10201 gcaaacaaaa attttagcgg aagaagcatc tgggaaagag atggagatgg gattcatttt
    10261 tatccatggg caggatcatt taatgaccac tttattgctg agagatctga ttcaagactt
    10321 tattgtactg tacagacaga atcaaggata ggagaagaac gctatggatg gaatcattaa
    10381 acaaatcgaa aaagggaaac cattttttga aaaaatctca cgtaatagtt atttaggagc
    10441 cgttcgtgac ggatttttaa cagcgatgcc agctatttta ttttcaagca ttttcatttt
    10501 gattgctgcg gttcctgaga tttttggtta ccaatggcct gaatctgtct ccacatggct
    10561 atggaaagtc tataattatt cgatgggtgt tgtagggtta ctcgtttcag caaccactgc
    10621 tcgctgcttg gctgattcga tgaatcgtcg cttaccgaaa aacaaagtaa tcaacaccac
    10681 ctctgtgatg ctggcctctg tggtaagttt cctgttgtta agcgtctctc cgattgaagg
    10741 tggattttca acggaatata tggggacaaa gggactactg gcttcctttg tcgctgcatt
    10801 tttaacagtt aatttatata agttttgtgt gctgaaagat attaccatta aaatgcctaa
    10861 agaagttcct ggaacgattt cgcaaacctt ccgagatatt tttcctttct ctttttcagt
    10921 atttgcggcc gttttaattg atttaggcat tcgacaaatc ttccaaatct catttgcaga
    10981 agcaatcatt acggtgctgc agccgctatt tacagcagct gacgggtact taggaatcgc
    11041 tattatctgg ggagcgatgg cgctgttttg gtttgtcggt gttcatggac cgtcgatcgt
    11101 ggagccggca attgcggcaa ttatctatgc caatgtggaa accaatctgc aattgttcaa
    11161 ttccggtgaa caagcttcta aagtactgac ggtgggttta gggaattttg taggaactat
    11221 gggaggaact ggggcaacat tggttgttcc ttttatcttc ctactctttg ctaagtctaa
    11281 gcagttgaag gcagttggga aagcttcctt tattccagta agtttcgctg tcaacgaacc
    11341 attgctattt gcggcaccca tgattttgaa cccttatttt tttattccat ttttgttaac
    11401 acctgttgta aacgtttgcc tgttcaagtt ttttgtcgat gtattgggca tgaacagctt
    11461 tatgtacgtt ttgccttggg caactccagc accgatcggt ttggttctag gaacgggcat
    11521 gggtatctta gcttttgttc tagcagcggt tctaatcgtc gttgacttcc tgatctatct
    11581 accattttgc aaagcatacg atgctgtctt agtagagaaa gaagcacaaa aagcagaggt
    11641 gatcgcaacc gaggaaggtg cttctgccga tgtacgtgag gaagtacctg tggcagcgag
    11701 tcaagttatc agcgatgcaa ataaagaaat caatgtgttg gtactttgtg ctggcgcagg
    11761 gacaagtgcg atgttagcta atgctttaaa aaaaggtgca tctgaatcga aagcaccgat
    11821 cagtgcaatg gcgggtgctt atggttctca ttacgaaatg ctgcaggatt ttgatatggt
    11881 ggtcttagca ccgcaagtca attcttacta tgatgatatc aaagaagaca ccgatcgctt
    11941 aggaatcaag ctggttgcga caaaaggagc agaatatatc ggattaacga gagatcctga
    12001 aaaagctgtt cagtttattc tgaaccaatt tcaataaagg aggagccata atgaaaatgg
    12061 gaatttggtt gcgtaaagct gttttatttg cagctgtgtt aggggctttg ggggctgttt
    12121 caaaaactgt tgaagcatct gccagcgaat ttattcgcgg agcagatatt tcgatcctgt
    12181 cagatatgga aaaatctggt gcaaaatatt atgaagacga tatttcaaaa gatgccttag
    12241 agattttaaa aaataatggt gtcaactatg ttcgactgcg tttgtggcag gatccttata
    12301 atagtaatgg agaaagttat ggagcaggga caaatgatct ggaaacgacg attgaccttg
    12361 caaaacgagc aaaaaatctg ggacttaagg tgctgctgga ttttcactac agtgattttt
    12421 gggttgatcc tgggaaacag aatcttccta aagcatggca aggtctgacc tttgaagaaa
    12481 tgaatacggc attgtacgac tatacaaaga acgttctgtc ggaaatgaag cagctggacg
    12541 tttatcctga tatggttcag atcggcaatg aactgaatag cggaatgctc tggccttatg
    12601 gcaagtcttg gggagaaggc gggggagaat ttgatcgatt ggctgctttt ttgaagtctg
    12661 gtatccaagc tgttcgagac actcaaccta aaacaactcc agtaatgctc cacttagctg
    12721 atggtggcga tacaggagca tttacttggt ggtttgatga aatcacgagt cgaggtgtgt
    12781 catttgattt aattggagtg tcgtattatc cgtattggca cggttcaatg aatgaacttc
    12841 aaaccaatat gaatgcgatc agccaacggt atggtaaaga agtgatcgta gttgaaacag
    12901 cttatgggca tacaacagcg aatgccgata ctatgccaaa tgcttttggt gaagccgaag
    12961 cagctgcggg gggatatgaa ccaacaccga caggacaagc agagtatttg ctggatcttg
    13021 ccgatcggat tcaggcagta ccgaataatc gcggggcggg cttcttctat tgggaacctc
    13081 tttggtacaa cggaaatgtg agttgggcaa cacaagcagg tatgaattat ctcagtgttc
    13141 aatccactat gggaaacgaa tgggacaacc aagcgatgtt tgattttgct ggaaacgcct
    13201 tgccaagctt gcgtgcgttt aaacaagcag gggcgcaaat aaatctagtt aaaaatgcaa
    13261 gtttcgaaag cgatggacca acgaccagtc cttccaattg gcaaacctgg tttcaacaag
    13321 gaaccgctaa gggtacgatc aaaacggaag cgggcacttt ttttggggac tacaaactaa
    13381 ctttttggca ggatcaagca tacgaggcat cagcttatca aaatgttagt ggcataagca
    13441 aaggaactta cacattgagt gcctatgtaa tgtctggggg agagtttgat actaatcagt
    13501 tatatatcaa aaattatggt ggagcggaac taaatactgc ggttgttaaa acaagtgaat
    13561 ggacaaaaat tacaatcaaa gacattccaa ttacaacagg tgtttgtgaa attggggttt
    13621 atagcaaggc ttcaggaaat gcttggacga acgttgattt tgtttcattg gtgaaacaat
    13681 agactgcgga tcgtttcgat tcaagatcgg aggttccctt cagccacatc gttagcgtag
    13741 aaggcaggaa tcgaacctgc acctcgcctt tgccaaaaat aaccagaaac gatttccagt
    13801 catttttacc aaaacgagta aagcaccaga cttcatctac actttgtatt atgctaaaga
    13861 gagttcaacg atttcgtaag aagcaatgaa aaaattgcaa aaagttgtgc agataacata
    13921 aagtttgttt aagaaagggt aaccttagaa ttccgtcgtg aatatgattt gagcacttag
    13981 atggatagaa aaaagttctc ggaaaacagt tcgtttttcg agaacttctt tttatgataa
    14041 gaatgaaaca aattaactta tattatagtc tcttttggta gggaaccatc ttatttttaa
    14101 tgaaaatcaa gcattttagc tattgaagaa tgttgattta tagggattcc ccctccatat
    14161 tatgttggct ctttattccc actccactgt tgctggtggt ttagaagtga tgtcatacac
    14221 gatacggttg acgtgggcta cttcgtttac gatacgtaca gagatttttt gcaagacttc
    14281 ccatgggata cgggcaaagt cagcggtcat tccgtcgatt gaagttacag cacggatacc
    14341 gactgtgtag tcgtaagtac gtccgtcacc cataacaccg acagagcgga tccctggaag
    14401 aacagtgaaa tattgccaga tatcacggtc aagtccagca gctgcgattt cttcacgcaa
    14461 gatagcatca gattcgcgta cgatttctag cttgtcttca gtgatttcgc caagaacacg
    14521 aataccaaga ccaggaccag ggaatggctg acgccaaacg attgaatcag gcatgcctaa
    14581 ctgagtccct aattcacgga cttcgtcttt gaataatgtg tttaatggtt cgatcaattc
    14641 aaattgcata tcttctggca gtccacctac attatggtga gatttgatcg tctgtgctgt
    14701 ttctgtacca gattcgataa cgtcagtata caacgttcct tgtgctagga aagagacgcc
    14761 ttcttcacca gcaagttttg ttgcttcgtc atcaaaaaca tatacgaatt cattcccaat
    14821 gattttacgt ttttgttctg ggtcagatac acctttcaac ttgtctaaga agcgatctct
    14881 tgcattgact ttgatgatgt tcaagccgaa ttttccgcct agactttcca ttacttgttc
    14941 cgcttcgcct ttgcgtagca gaccgtggtc aacaaagata gatgtcaatt ggtcaccgat
    15001 cgctttttgt aaaagaaccc caacgacact agaatcaacg ccacctgaaa gaccaagcaa
    15061 gacttttttg tcaccaactt gttcacggat tttttctact tgcatatcga taaagttatc
    15121 cattgtccag ttaccttcac agtgacaaac atcaaaggca aagtggcgca gcaattcgat
    15181 tccgtattcg gaatgacgta cttctgcatg gaattggata ccataaaaat tacgtgttgt
    15241 gtcttggata gaagcaatcg gacaatcttt gcttgttccg actgtttcaa agccttcagg
    15301 aactttagtt accaagtcac catggctcat ccatactgtt tgttgttttg gtgtttcttt
    15361 aaacaagaca gcttgatcgc ttgttacttc taacaaggct ttcccatatt cgcggttttt
    15421 agcaggctct acggaaccgc caagtttgta cgtgatcaat tgcataccat agcaaatccc
    15481 taatacagga atacctaaat tgaagatctc aggatcgatc ccaaatgcat tctcatcata
    15541 tacactgttt ggtccgccag aaagaatgat tccctttgga ttcatcgctt ttacttcttc
    15601 tgcagtaatg cggtggctca ataattcgga aaagactcca agatcacgaa tacgtcttgt
    15661 gatcaattgg ttatactgac taccgtagtc taatacgata atcttttcaa cgttcgtcat
    15721 atcggcaacg tttgtcaaat ttattacccc tatcccttta aattttatct caaaatagtc
    15781 aaactatttt aaaatgctaa tattttcgca tgaaaatcga atcgatgata tgattttcag
    15841 ttttatggag aattatatcg gctcttcctc gtgtaggcaa gatatattcc tgtaaatttt
    15901 tcaaattcac atttttccat acatcttttg ccattttaaa ggcttcttca cgatctccga
    15961 tagcaaaacg ataataataa ttctctggat tttggaaagc cgtatccagt aacgcaccaa
    16021 aacgatccaa ataccatttt tcgatcagca cgggatcggc atcgacatag acagaaaaat
    16081 caaaaaagtc gctgacgtag atttgctgat tcgcaggtaa ttgaagcgta ttgatcccct
    16141 caacgatcaa gatatcaggc tgctggatca attcgtactt gtctggaatg atatcataca
    16201 catcatgtga gtaaacaggt acttttatct cttcctgacc agattttaca cggttcaaga
    16261 aatcgatcag catctccata tcataacttt caggaaatcc tttacggtcc atgattccac
    16321 gctcttttaa tatacgattt ggataaagaa atccgtcagt cgtgatcagc tgaacgtttc
    16381 ttcgtttgaa ggtacgagac aaaatcgtct gcagcagtct ggctgttgta ctttttccaa
    16441 cggctacact tccggcgatc ccgataataa aaggcggtac ttctacgtat ttatgaagaa
    16501 ataaaccttt actcaagaac aaagattcaa attctttcat ataaagataa atcagatgag
    16561 caagaggtac atagatatct cgaacatcct gcatggaaat gcggtcattc aaacttttga
    16621 tattatctag ttcatcttgt gtcaaaggtg cttgcccatt acgataaaat tctcgccatt
    16681 cttctcttgc cacacggtag tagttcattg gatcattcat attagcctcc tgcgttctcc
    16741 catcaatgga actattttaa cacaaaataa acgcaaaccc caccacttaa gagagattgc
    16801 cgatcttttt gtataatctt tataatagaa agaaacggag tcttattctt gacttgcgca
    16861 cggatacata aaaggataga ctgttgtcat gaaagaaatg agaaggatgg aagacatgac
    16921 aaatcattac tattctgaac gcccagatac ggcgcacgat tttgaacaat gggcttttga
    16981 gttaaaaggc agaacctttc aatttgtaac agattctggt gtattttcac gtgaaacagt
    17041 ggattatggt tcacgtgtcc tgattgatgc tttcgattgg gaagagttac ctgatgaagg
    17101 aaagatctta gatgtgggat gcgggtatgg accgattggg ttagctttgg catttgcgac
    17161 acagcggttt gttgaaatgg tcgacattaa tgaacgagcg gtaagtctag cgcaaggaaa
    17221 cgcaaagcgt aaccaaatcg aacatgttga tatccatcaa tcgaatatct atgaagcagt
    17281 tcatgaagaa acctatgcag ctatcgtaag caatccgccg atccgtgctg gaaaaaaagt
    17341 tgtacatgaa attttgacag gcgcatatcc tcggttgaag aagggcggta cactgacaat
    17401 tgtgatccag aagaaacaag gagcgccgag tgcgcaaaag aaaatggaag aaacatttgg
    17461 taatgcagaa atcgtcacaa aagataaagg atattatatc atcaaaagtg tgaaagaata
    17521 actagctgaa aaatagtgga gcgacgaaag agtggaactg ggcgtgcatg tacgggtacg
    17581 tatcagttct ttttttgttg agaagttttt aaaaacaaag aactattttt tcttcaaaaa
    17641 gaaatagtag gaacagagtc gttgtttttt acgataaaat aaataagata cagaacttgt
    17701 atagaaggct gccaagtcgg tagataaagg aggtttttat caaaaaacat actttccttt
    17761 tttctctatt cttttcttgg gggttttggt acactgatag ggaatttaga tagaagggag
    17821 ccaataggat gaagctgacc atcagagata tcgcagaaat ggcaggcgta tcagtaacaa
    17881 ctgtctcaca gattttgaat aacaaaggaa gcagatttag tgataagaca agaaaaaaag
    17941 tgttgtcgat cgtgaatgaa catcattata agcccgatta tttcgcttca aatgtgatca
    18001 atcgacattc aaagaccatc ggaatgatcg tccctgatgt cactgatttc ttcttctcca
    18061 aactgatcga aggtgtagag agctatttga atcctttggg ctatgtgatc atgttatgca
    18121 attctcgtca tagccaagaa aatgagatca agtatttaca agagctttcc caccgctcag
    18181 tggacggaat cttgctggcc acaccaaata ttttacctga gaaatatgca ttagacagcg
    18241 gtttttatca aaaaatgcca atcattttaa tcgatcgcgg attgaatcgt cgggataacg
    18301 gacggcttat cgtaaaggaa tatgagggcg cctatcaagc tgtttcgctg tttattgaaa
    18361 atggccatac gaagatcggc atgctgaagg aaaccactgg atactatcaa ttagaagaac
    18421 gtttcaacgg atatcgtcat gcgctgaaag atcatggcct gccttttaat gggaaatttg
    18481 ttgaacatgg agagttgact gtccaaggtg gatatactgc atcaaaaaaa ttactcaaac
    18541 ataaagatat cacggctatt ttttgcggga atgatgccat ggcgatcgga tgctatcagg
    18601 cgatcgatga attgggcaaa aaaatcccag aagatatctc agtcatagga ttcgatggat
    18661 taaagctgtc agaatacatg attccgcaat tgacgacagt gcagcagcca agttttgata
    18721 ttggatttta tgctgcacgt ttcctgatcg atacgatcga atttcctcaa agaaaagttc
    18781 cgaacaaagt gttcgaaaca aaattaatta ttcgtgagag cgtaaaagta ttgacaaagg
    18841 gctaactcgg cggtatattg cttatgtaag catttacaaa ggctagttag tgcttttttt
    18901 atttttagta aaccagttta ctaaagtggt ttacctttcc taaaaataat gtataatacc
    18961 gaatgaagac aaggaggatc aggcaatgcg aatggtggat ctgattgaaa aaaagaggga
    19021 tggaaacgag ctgtcgaaag aggaaatcga gtacatcgtc acgaactata cgaatggaaa
    19081 gattccagat tatcaagtca gtgcattatt gatggcaatt ttttatcaag acatgacaaa
    19141 tgaagaaatc acgaacttaa cattggcgat tgctaattct ggtgatgtca tcgatttgag
    19201 ttctcttgaa ggaataaagg tagataagca ttcgacaggt ggcgttggtg acacgaccac
    19261 attgatttta gcccccctag tagctagtgt cggagtgaca gtggctaaaa tgtctggacg
    19321 cggtctaggt tacacaggtg gtacactaga caagctagaa gcaattcccg gatttcagat
    19381 cgagctttcg gatgaagaat ttgtacgcat tgttaatgaa agtaaagtag cggtaattgg
    19441 tcaatcagga aacttggcac cggcggacaa aaaattgtat gccttgcgtg acgtcacagc
    19501 gaccgttgat tctcttccgc tgattgccag ttcgattatg agtaaaaaaa tcgcggcagg
    19561 agcagatgca atcgttttgg atgtgaccac tggagacggt gctttcatga agaacatcga
    19621 agatgcaaga cgtctggcaa agaccatgac gagcattggg aaactggcta accgagaaac
    19681 agtggcggtt atctcagata tgtcagaacc tcttggcgaa gctatcggaa atagtctaga
    19741 agttgtcgag gcaatcgaaa cattacaagg aaatggtcca gaagatctag tagaaatgtg
    19801 ctacgcctta ggaagccaaa tggttgttct tgctggcaaa gctaagacaa ccgatgaagc
    19861 aagaacgttg cttcaagaag ctctggaatc aggtaaagcg ttagcaaaat tcaaagaaat
    19921 gatccaaaat caagggggag acccagcgat cgtggaacat ccagaacgaa ttttgactgc
    19981 acgctacaca atggagcttc ctgctaaaca aagcggagtt gtgtcaaaaa tcgtggcaaa
    20041 tgaattagga attgctgcaa tgatgctagg tgctgggcgt aaaaccaaag aagaagatat
    20101 tgatcacgct gttggattga aactgcataa aaaaattggt gacactgtga caaaaggtga
    20161 gtcactattg acgatctata gtaacgacga agaaatcact tctgtcattg aattattata
    20221 taaaaatatt gaaattggtg aatcggcaat gaagccaacg ttgattcatg acatcatcac
    20281 agaataaagg aaaaaagcgg actttaccgt tttaaagaaa aggggaaaag aaatggaact
    20341 aaaccgaatg atcgaccata ctattttgaa agcagacgca tctaaagaag ctgtgatgca
    20401 aattatcgaa gaagcaaaaa aataccattt ttattctgtc tgcatcaatc cagcatgggt
    20461 tgcgctagcg aaagaacaat tacaaggtga gccagtagcc gtatgtacag taatcgggtt
    20521 tcctctagga gcaaacacac ccgagacaaa agcatttgaa acaacagatg ccatcaataa
    20581 cggtgcagat gaagtcgata tggtcatcaa tatcggtgct ttgaaatcaa aggatgatca
    20641 acaagtccaa aaagatatcg aagcagttgt tgaagcagca aaagatcgtg cgcttgtcaa
    20701 agttattatt gaaacatcgt tattagatag agaagaaatc atccgagctt gcgaaatagc
    20761 aaaagctgca ggcgctgatt ttgtcaaaac atcaactggt ttctcaacag gcggagcaaa
    20821 ggtagaggat gtccgtttga tgcgtgaaac tgtaggacca gaaatgggtg tcaaagcttc
    20881 cggcggtatc cataacgaag aagaagcaat ggcaatgatc gaagctggtg ctacaagaat
    20941 cggaacaagc gcaggagtag caatcgtatc tggttcaact ggtgaaggct attaattttt
    21001 tcaaaggaga agctcatggc agaactcaaa caagaatgga tcaacacagc tattgaagcg
    21061 ttagataaag cctatgttcc ttattcccat tttccggtag gcgcttgtct cgtaacggaa
    21121 tcaggcaaga tttatcaagg catcaacatt gagaatgcat catttggatt aacgaattgt
    21181 gccgagcgca cagctttttt caaagcagta tctgaaggag aaaaaacatt tacgcatcta
    21241 gtcgtagcgg ggcacacccc cgatcctatc tctccttgtg gtgcatgtcg acaagtaatg
    21301 gcagaattct gttcccctga tatgccggtt acgctagtag gagacaatgg tgtgacgaag
    21361 gcaacgaccg ttcgtgcact gctgccttat gcatttactg aaaaagatct ataactcatg
    21421 ttcattcagt cagctgactg ttgaaaaata aaacaattat tttaggaggc tttacagaaa
    21481 tgaaaaaagc aaaattattt ggtttaggtg ctgtcgcact agcagcaggg ttatttttag
    21541 gtgcatgcgg caacaacggc tctactgatt catccggtgg caaaagctca tcagacacaa
    21601 caactgcagc attgatcaca gacacaggtg gtgtagacga ccgttcattc aaccagtcag
    21661 cttgggaagg actagaaaaa tgggggaaag atcaaggact ttcacgagga aatgatggct
    21721 tccaatattt ccaatcttca aatgaatcag attacatccc aaatattgac caagcattga
    21781 atgctggatt caaaacgatt tttggtattg gttataaact aaaaccagcg atccaagaac
    21841 aagcaacaaa caatacaggt acgaactttg ttattatcga tgatgtcatc gatggattag
    21901 ataacgttgt atctgcaact ttcaaagaca acgaagcttc ttatcttgca ggtgttgcag
    21961 cagcttatac gactgaaaca aacgtagtcg gctttatcgg cggtgtaaaa ggtgaagtaa
    22021 tcgatcgttt tgatgctgga ttcaaagccg gtgttgatgc aggtgcgaaa gaattaggaa
    22081 aagaaatcaa agtattgaat caatatgctg gtgacttctc tgctccagat aaaggacgtt
    22141 caattgctca aggtatgtat gcacaaaacg cagatatcat cttccatgct tcaggcggta
    22201 caggtaacgg tgtattccaa gaagcaaaat cattgaacga atcaggcgac aaaaaagttt
    22261 gggttatcgg tgttgaccgc gaccaatcag acgaaggcga atacacatta aacggcgaaa
    22321 agaaaaactt cacattgaca tctacactga aagcagttgg aacagtagta gaagatttgg
    22381 cacaaaaatc agcggacggt aaattccctg gcggcgaaca cactgtttat ggattgaaag
    22441 aagacggtgt tggtctaaca gaaggacaac tttctgacga agcgaaaaaa gcagttgatg
    22501 aagcaaaaga aaaaatcatt tcaggtgacg taaaagttcc agaaactcct gaagaaaact
    22561 aaaaccattt ctatagcctt gttagacaca tgtttgacaa ggctatggtt tgattagaac
    22621 aagaattgtt catttatcca agctgccttg tgacagtttg gataagggaa caactccctg
    22681 aagtaatgtt tgtttcaaaa gaagaacgct cactaagcgt gaatcttagt caatcgttgc
    22741 cctagataga aatcgttagg atgtgaaaaa aaggtggttc aagaaaatat tgtcatagaa
    22801 atgcagaata ttaccaaaga atttggaaca ttcaaggcaa atgacaacat caatttacaa
    22861 gtaaaggcag gagaaattca tgcgttgctt ggagaaaacg gtgctggcaa atctacattg
    22921 atgaacgtgc tttccggatt attagagccg acatcaggga aaattttgat gcgtgggaaa
    22981 gaagtaaaga tcacaagtcc gaccaaagcc aaccaattag ggattgggat ggtccatcag
    23041 cactttatgc ttgttgatgc ctttactgta acagaaaaca tcgtgttggg aagcgagcct
    23101 agtcgcgcag ggatgcttga ccataaaaaa gcacgaaaag agatccaaaa agtttctgaa
    23161 cagtatggat tgtcagtcaa cccagatgct tacgttcgtg atatttcagt tggaatggaa
    23221 caacgggtag aaattttaaa aacactttac cgaggagcag atgtactgat ttttgatgag
    23281 ccgacagctg tattgacccc tcaagaaatt gatgaattaa tcgtgatcat gaaggaatta
    23341 gtcaaagaag gcaagtcgat cattttgatt acgcataagt tagatgaaat caaagcagta
    23401 gctgaccgct gtacagttat ccgccgtgga aaaggaatcg gtacagtcaa cgttaaagac
    23461 gtaacctcac aacaattagc cgatatgatg gttggaagaa cggtttcatt caaaacgatg
    23521 aaaaaagaag cgaagcctca agaagtcgtt ttgtctattg aaaatctagt ggtgaaagaa
    23581 aatcgtggat tagaagccgt gaaaaacttg aacttagagg ttcgtgctgg cgaagtactt
    23641 ggtatcgctg gaatcgatgg aaacgggcag tcggagttga tccaagcttt gactggtttg
    23701 cgaaaggcag aaagcggaca tatcaagcta aaaggggaag acatcactaa taaaaaaccc
    23761 cgaaaaatca ctgaacatgg tgtaggacac gtgccagaag accgtcataa atacgggtta
    23821 gtcctagata tgacattatc tgaaaatatc gcactacaaa cctatcatca aaaaccttac
    23881 agtaaaaacg gcatgctgaa ttattcagta atgaatgaac atgccagaga attgatcgaa
    23941 gaatatgatg ttcgaacaac gaatgaactt gttcccgcaa aagctttatc aggcggaaat
    24001 cagcaaaaag caattatcgc tcgtgaagtc gaccgagatc ctgatctgtt gattgttgca
    24061 aatccaactc gtggactgga tgtaggtgcg atcgaattta ttcataaacg tctgatcgaa
    24121 caaagggaca aatacaaagc agtgttactg atcagtttcg aattagaaga aattttaaat
    24181 gtttcggatc gtattgctgt tatccatgaa ggagaaattg tcggtatcgt tgatccgaaa
    24241 gaaacatctg aaaatgaatt aggtctattg atggcgggct ataccttaga agaagcacga
    24301 aaagagttag aaaagggggc tggcgcacat gaatgatcgc agcgaaaaat tccgtaattt
    24361 attagtgcct gtactttcag ttgttttagg attgatctta ggcgcgatat tgatggctgc
    24421 ttttggtttt cagcccatcc aaggttattc ttctatgcta gatgcagccc ttggttcgca
    24481 aagagggata ggtgaaacgt taaggcaagc aacgccgttg atttttacag cattaggttt
    24541 ttctgtagct aactcagctg ggtttttcaa tattgggctt tctggacaag cactttgcgg
    24601 gtggatcgtc agtgtctggg tggcacttgc gtttccagat ctgccaaaag ttgttttgct
    24661 tccgttatgc gtgatcttag gtgccttagc tggtgcgatg gcagcggctg ttccaggttt
    24721 acttcgagca ttttttggaa caagtgaagt gatcgtaaca atcatgatga actatatctt
    24781 attatacgta agcacatttg ctttacatga agtgatgcct gaaagctatc gctcaagttt
    24841 ggactcttcc aatatgatca gtcaaaatgc ctcactgcgg ttaccatggt taacacaagc
    24901 ttttggcggc tctcgcgtaa actcaggatt atttttagca atcatcgcgc ttattttcgt
    24961 ttggctgctg atgaagaaaa cgactttagg atttgaaatc cgttctgttg gattgaatcc
    25021 ttttgcttct gagtatgcag gaatgagtag taaacgtacg atcgttttgt cgatggtcat
    25081 ttctggcgct ttggcagggc ttggcggtgt ggttgaagga ttaggaacgt atcaaaactt
    25141 ctttgttcaa acgacttcgc tatctattgg atttgacgga atggctgttt ccttgcttgg
    25201 ttctggatca gcaatcggta ttcttttatc agcgatcttg ttcagtattt tgaagatcgg
    25261 tggacttggc atgcagacag gagcaggtgt tccgtttgag atcgtcaatg tatcgattgc
    25321 tttgattatc ttctttgtcg ggatcaactt cctgattcgt ttcgtcatgg ctaaagtctt
    25381 ccaagggaaa aaacaagaag agatcgttgc gacaatagaa tcgaaaccaa cgaatcaaaa
    25441 ccatgaaggg ggcgaactat aatgtcgact atcgaattaa ttgccttgat ccttacttct
    25501 acactggttt attcaacacc gctaattcta acgtcactag gcggaacttt ttctgaacga
    25561 agcgggatcg taaacgtagg gctagaggga atcatggtca tgggtgcttt tagttccatc
    25621 gttttcaact tgacgatgag tccatcactt ggttctatga caccatggat cgctatttta
    25681 gtgggtggcg tcgtaggtat cctattttct ctgattcacg cagtagcaac agtcagtttg
    25741 cgtgctgacc atattatcag cgggacagta attaatctga tggcacctgc tttaggtgtt
    25801 ttcttgatca aagcatggta tggtaaaggt caaactgata acatcacgca gaatctgggg
    25861 tatttttctt tcccaggatt agcagatatt ccggtcattg gaccaatttt ctttaaaaat
    25921 acattcttac ctgcttattg tgctattttg attgctgtcc tagcttgggt gatcatcttc
    25981 aagacgaaat tcggcttgcg cctccgttca gttggtgaaa atcctcaagc tgccgacaca
    26041 ttaggtatca atgtatatgc tatgcgttat tcaggcgtac tgatttctgg cttgttaggc
    26101 ggtatgggcg gtgctgtttt tgctcagtcg atttccggta acttttcagc tggtacgatc
    26161 gttggacaag ggttcatctc catggctgct atgatctttg gtaagtggaa tcctttaggg
    26221 gcaatgggtg cctcattgtt ctttggtttt gctcaaagct tgagtatcat tggcgcacaa
    26281 ttaccagtta tttcttcgat tccgccagta ttgctgcaaa ttgctccata tttgctgaca
    26341 atcattgtgc tggttgtttt cttagggaaa gcttctggtc caaaagcaaa cgggaagaac
    26401 tatatcaaat caaaataatc ttttagcgaa taaaaagggt gggttacggg aagtgttttt
    26461 cgtctcgccc tttttgtttt aaaggcaata aaaataaaaa gaaagaagga ataatcatgt
    26521 ttaaacgcgt acatctgatc gtcatggatt cagtaggaat tggagaagca ccagatgccg
    26581 ataagttcgg tgatgttggt tctgatacat taggacacat tgcgaaagaa gcaggattga
    26641 acgttccaca tttagagcag cttggtttag gaacgatccg tcctcttgaa ggtgtggaat
    26701 cagtgaaaga tcatcaaggc tatgcgacga aattagaaga agtttctgta gggaaagata
    26761 cgatgacagg ccactgggaa atcatgggat tgaatatcaa aactccattt cgtgtgtttc
    26821 ctaatggatt ccctgatgat ctgatcaaac aaatcgaaga attttctggc cgtaaagtcg
    26881 tatgtaacaa accttatagc ggaacagctg ttattgacga ttacggtgaa caccaaatga
    26941 aaacaggcga tttaattgta tatacttctg ccgatcctgt ccttcagatc gcggcacatg
    27001 aagaaatcat tcctttagaa gaattatatc ggatttgcca attcgttcgt gatataacaa
    27061 aagatgatcc gtatatgatt ggccgaatca ttgcacgtcc gtacgtgggt gaaccaggag
    27121 acttcacacg aacaagcaat cgccatgatt atgcgttgaa tccattcgga cacacagtcc
    27181 ttgattcttt gaaagaagca ggaaaggacg tgattgctgt tggaaagatc aacgatattt
    27241 tcaacggaca aggaatcact gaatctgtcc gcacgaaaag caatatggat ggcgttgacc
    27301 agctgctgaa agttatgaaa aacgattttt caggaatcag ctttaccaat ttagtagatt
    27361 ttgatgcatt atacggtcat cgtcgggatg tagtcggcta tgcgcatgcg attgaagaat
    27421 ttgacttacg aattccagaa ttgcttgaag cgatggaaga agacgacttg ctaatgatta
    27481 cagccgatca cggaaacgat ccgacgttta ctggtaccga tcatacgcga gaatatgtac
    27541 cgttattggt ttacagtaaa aaaatgaaag aacaaggggc attgcctcaa ggatattatt
    27601 cagatatttc agcaacgatt gctgagaact ttagtgtttc ttcgactgaa aatggcgaaa
    27661 gcttcttgaa attattaaaa taatcttttt aaataggaga aagcaaatga ccaagttaag
    27721 cgagatgtta caagaaacga cccagtttat ccttgataaa ggagtaaaag aaattgattt
    27781 tggtttgatt ctaggttcag gattaggtga attagcagat gaaatcgaag atgctgtaat
    27841 gatttcttat gatgagatcc cgttctttcc tgtttcgaca gtagttgggc atgcaggaaa
    27901 gctagtttat gggtctctgg caggcaagaa agtgttagcc atgcaaggga gattccacta
    27961 ctatgaaggt cattccatgc aaacagtgac ctatccagta cgtgtgatgg ccggactagg
    28021 ggcccattca gtcattgtga ctaatgcatg tggtggtgtc aacgaatcat ttgtaccagg
    28081 agatttgatg ctgattaccg atcatatcaa ttttactggt gaaaatcctt tgatcggtcc
    28141 gaatgaagat gcaatgggcc ctagatttcc agatatgagt caagcttata cgcctgacta
    28201 tcaagcaaca gcaaaagcag cagcagaaaa actaggtttg gatcttaaag aaggcgtata
    28261 tatgggctat tctggaccaa cttatgaaac gcctgcggag atccgaatgt ctcggacaat
    28321 aggagccgat gcagtaggga tgtcgactgt tccagaagtc atcgtagcag ctcacagcgg
    28381 attaaaagtg ttaggaatct cttgtattac caacttagca gcaggtatgc aagcgaatct
    28441 gagccatgaa gaagttgtag aaacaactca gagagtcaaa caatctttta aagcattggt
    28501 taaagaaaca ttgacattat tgtaatagga ggaacaataa aatgagtgtg catattgaag
    28561 cgaaagaagg cgagatcgcc gataagattt tacttccggg agatcctttg cgagctaaat
    28621 atattgcgga gacttttttg gaagatccag tttgttacaa tcaggtacgc ggtatgttag
    28681 gctttaccgg caaatataaa ggagaacgta tttctgttca aggaacagga atgggaatgc
    28741 catcagccac catctatgcc catgaattga tccagtcgta tggtgtaaag aaattgattc
    28801 gagtaggtac atgcggtgca ttgtcaaaag acgtccatgt tcgtgattta gtactagcac
    28861 aaggtgcagc gaccagttct tcgatgatcg aaaaaaattt ccaagccttt cattttcctc
    28921 caatcagtga tttcaatcta ttactgaaag catatgagat agctaaagaa aagggctata
    28981 cggttcatgt aggaaatgtt ctttcggaag attctttcta caaagatgat ttgacagaga
    29041 cgttccaatt agctgaactt ggcgttttag gagtggaaat ggaagcagcg gctctttatt
    29101 acttaggcgc gaaataccat gtgcagacat taagtttgat gaccgttagc gaccatttga
    29161 tcaccggtga agaaacaaca gctgcagaac gtcaatctac gttcaatgaa atgatcgaag
    29221 taggattgga aacagcgata gcagaataag aaggaaatga aaaagctgcc ctgcattaag
    29281 taataagaac atccaagcaa aaatagctcc tcatgttttt gacttggctg gacttattat
    29341 tgcaaatgta agcttttgaa caccgtttac caagaggttg tgaatctgcc gtttaactct
    29401 gagtcacaag gaacaatttc aaaaaacagc ttttcatgtt tgatgaatat tgtgacttgt
    29461 gaccgagaag ttggcaggag aaaaccgttt atacgaaaaa agggactgtg acaaatcgtg
    29521 tcacagtccc ttttttatag gtagtatttt ttagcaactg ttaagtcatc atttaattca
    29581 taaacaagtg gttgacctgt tggaatttca agatccatga tgtcttcgtc agagatacct
    29641 tcgatatgtt tagctagggc gcgtaatgag ttaccatgtg cagctactaa aacagttttg
    29701 ttgtctagta atgctggagc aatttcatct tgccagaatg gcaaagcgcg ttctaatgtc
    29761 actttcaagt tttctccacc aggaatatcg cgtttgtcta acattgcgta acgacggtca
    29821 tttgctgcag aaccttcgtc agtttcttcc attaatggag gaagagtatc gtaagaacga
    29881 cgccagatgt gcacttgttc gtcgccgtat ttttcagctg tttctttttt gttcaaacct
    29941 tgtaatttac catagtgacg ttcgtttaag cgccatgatt tgatttgtgg tacccaaagt
    30001 tgatctgaat attctaagat caagttacat gttttgattg cacgagttaa aacagaagtg
    30061 taagcaacat caaattcgat tccagcttct ttgattttgc gtccgccttc ttttgcttct
    30121 tcgattcctt ctggtgctag atttacatca gcccaaccag taaattggtt caatgcattc
    30181 cattcactaa gaccgtgacg agaaaaaact aattttggca tgtttagctc tccttttaag
    30241 ataggtttat atttctgaaa ttttcagttc tgttttattg tacaattttt tggaagagat
    30301 ttccatcgaa aaattagata agattctatg agaaaacaag tagagaatat aaaaaaacga
    30361 acagtgccca cgcaactgtt cgtttttagg tattagatgc ataattgctc gatttctttt
    30421 tcaggtaaat tgatatattt ataacatgtt ccaactgaaa caccgcattt tgaagaaata
    30481 aattggatcg tttctttttt ttcataatag agacgtcgga tttttttgat cgtttttgca
    30541 tcgatttttg gtcttccgcc gatttttcct tttttacgag cttcatctaa tccaactaat
    30601 gtacgttctt tgatcaatgc gcactccatg tttgctaggt tttccattaa ttggaaatag
    30661 atttttccca tttcgcgcgt atcgattcct tcatcaagac taatcaagtg cagcccgcga
    30721 tctttgaata attgcgtgag ttctgttaat tgccgcgtag atttgcctaa tcgatgaagt
    30781 tggcaaatga ctagtgcatc gccttgttgc atgtcagcga tcactgactc caaatgaaca
    30841 gcagtagaat cattttgttc cacttcatat gtctcatgga aaatttcttg acaaccaaag
    30901 tcagataatt gatcaacctg agttgttaaa tcaacgtcat ttatggttgt gcgtgcataa
    30961 ccaataattt tcatggtgat tcctttctag cagtgatttt ctaactggat ataacagtaa
    31021 aaatgtagca taaagtacgt caaaaagata gttttttcgc aaattttccg ctgtcttttt
    31081 ttattggatg atcaagcagt ttttctttat ttacgacgga ttgcgtcaag aatctcaacg
    31141 cctttttctg agccgacaac tactttagaa accatgttta ggaaaagccc atgttctact
    31201 accccaacaa gttcatctaa ataggtagct aagctttctg gctgttcgat gacttctaga
    31261 tgcagatcaa tgatgtaatg accaccatct gtggttaaga cttctccgtt ttcgtctgta
    31321 cgcaagacgg gttggaatct tttttcttca aaaatatgaa gtagctgttg ggagccataa
    31381 gggatcactt caactgggag tgggaacttc ccaagtttat cgactaattt agaagaatca
    31441 acgatccaaa tcgtttcttt tgagtacgta gcgactattt tctcgaaaag caaagcagcg
    31501 ccgccgcctt tgatcccttg aaaatcagca ctgatttcat cagcaccgtc tattgtcaaa
    31561 tcgactacgg ggacttcatc aatactcttt aacggtattc ctaatttttc cgcttgttct
    31621 tttgtcgcat ttgaagtagt aactcctgtg atacgtaaac cttcttcacg catacggcga
    31681 ccaatctctt ctaccatata ataggcggtt gaaccggtcc cgagacctac gatcatcccg
    31741 tcctttacga atttcgcggc ttcaatgcca gctaattgtt ttaaattcat ctttgcgtcc
    31801 accttttttt agtttgagca tcgtgctttc ctcactattt tagcgtgatt tacggtaaaa
    31861 agataccatt cttttttatt ccaataaagc tttttcaaaa aaaattgcat ctcttgttga
    31921 catgtttttt cattcgtgat attctaacaa aggtgcttta tctacaggtt tctgtgaaga
    31981 aacgtgctga ctgtttatca aagcatattt gataaggatg cagacattgc atttattttt
    32041 tatcacaaaa aaagaaccac ctggatgtgt ggaactaaac gcaaatcgtg ggaaggagga
    32101 aacaaggaat gcctacaatt aaccaattag tacgtaaacc tcgtaaatca aaggtggaaa
    32161 aatctaattc acctgctttg aacaaaggat ataacagctt taagaaaact caaactaacg
    32221 taaactcacc tcaaaaacgt ggggtagcaa ctcgtgtggg tacaatgaca cctaaaaaac
    32281 cgaactcagc tttacgtaaa tatgcacgtg ttcgtttgtc aaacttaatt gaagttactg
    32341 cttatatccc agggattggt cataacttac aagaacacag tgttgtatta ttacgcggtg
    32401 gtcgtgtaaa agacttacca ggggtacgtt accatatcgt tcgcggtgct ttagatactg
    32461 ctggtgttaa cgaccgtaaa caaagccgtt ctaaatacgg aactaaaaaa cctaaagctt
    32521 aattttaatt attaaacaaa tgaaacttgc ttctactata tagaagtaat tactatgaac
    32581 aatatttcgg aaggaggagt tacggatgcc acgtaaaggt cctgttgcaa aacgtgatgt
    32641 tttaccagat cctatttata actcaaaatt agtaactcgc ttgatcaacc gtgtaatggt
    32701 tgacggaaaa cgcgggattg cagctaacat tatctataat gcctttgact tgatcaaaga
    32761 atctacaggt aacgatccat tagaagtgtt tgaacaagca atgaaaaacg ttcaacctgt
    32821 tcttgaagtt aaagcacgtc gtgttggggg ttcaaactac caagtaccag ttgaagttcg
    32881 ccctgaacgc cgcgttactc taggtcttcg ttgggtagta aactacgctc gcttgcgcgg
    32941 tgaacacaca atggaagaac gcttagcaaa agaaatcatg gatgctgcaa acaacacagg
    33001 tgcttctgtt aaaaaacgtg aagacactca taaaatggct gatgccaacc gtgcgtttgc
    33061 tcactatcgc tggtaagatt ctctctgttt ggtcggcttt tataagtcga cctcagatag
    33121 tgtccttatt tttagcaact agatagtaaa gagaggagaa acaaggagaa tgaccagaga
    33181 attttcttta caaaacactc gtaatatcgg tatcatggcc cacatcgatg ctggtaaaac
    33241 gactgctact gaacgtatct tgtactatac tggtaaaatc cataaaattg gtgaaactca
    33301 tgaaggagct tcacaaatgg actggatgga acaagaacaa gaacgtggta ttacgatcac
    33361 ttctgctgct actacagcac aatggaaggg tcaccgaatc aacatcatcg acacaccagg
    33421 acacgtagac ttcacagttg aagttgaacg ttcattgcgt gtacttgatg gtgctgtaac
    33481 tgttcttgat gcacaatcag gtgttgaacc tcaaactgaa acagtttggc gtcaagcaac
    33541 aacttatggt gtacctcgta tcgtatttgc aaacaaaatg gacaagatcg gtgctgactt
    33601 cttatattca gtatcaactt tacatgaccg tttgcaagca aacgctcacc caatccaatt
    33661 accaattggt gcggaagacg acttcacagg aattatcgac cttgtaacaa tgaaggctga
    33721 aatgtataca aacgatcttg gaacagagat cgaagaaaca gaaattcctg aagaataccg
    33781 cgaattagct gaagaatggc gcgaaaaatt ggttgaagct gtagctgaaa ctgatgaaga
    33841 acttactttg aaatacttag aaggtgaaga aatcactgaa gctgagttaa aagaaggtat
    33901 ccgccgcgca acagttaacg tagaattcta cccagtacta tgtggttcag catttaagaa
    33961 caaaggggtt caattactat tggacgctgt tcttgattac ttgccatcac cgttagatat
    34021 cccagctatc aaagggattg accctaaaac tgatgaagaa gtagaacgtc ctgcagacga
    34081 cagcgctcct ttctcagctt tagcatttaa agttatgact gacccattcg taggtcgttt
    34141 aactttcttc cgtgtgtact ctggtgtttt acaatcaggt tcatacgtac aaaacgcaac
    34201 aaaaggcaaa cgtgaacgtg ttggtcgtat cctacagatg catgccaact ctcgttcaga
    34261 aatctctgaa gtttacgctg gagatatcgc tgctgctgtt ggtttgaaag acacaactac
    34321 tggggacaca ctatgtgatg aaaagagtct agttattctt gaatccatgg aattcccaga
    34381 accagttatc caagtcgcta ttgaacctaa atcaaaagct gaccaagata aaatgggtgt
    34441 ggctttacaa aaactatctg aagaagatcc tactttccgt gctgaaacaa acgtggaaac
    34501 aggcgaaaca atcatcgctg gtatgggtga acttcactta gatatcatcg ttgaccgtat
    34561 gcgtcgtgaa ttcaaagttg aagctaacgt aggtgcgcct caagtatctt accgtgaaac
    34621 tttccgtgct ggcactcaag ccgaaggtaa gtttgtacgt cagtctggtg gtaaaggtca
    34681 atacggtcac gtatggattg aatttacacc aaatgaagaa ggtgctggtt tcgaatttga
    34741 aaatgcgatc gtcggtgggg ttgttcctcg tgaatacatt ccagctgttg aaactggttt
    34801 gaaagatgct atggaaaatg gtgtcttagc tggctatcca ttagtagata tcaaagctaa
    34861 actttacgat ggttcatacc atgatgtcga ttcaaatgaa actgccttcc gtgttgctgc
    34921 ttctatggca ttacgtgcag cagctaagaa agctaatcca gtaatccttg aaccaatcat
    34981 ggctgtagaa gttgttatcc ctgaagatta tttaggtgat gttatgggtc acgtaactgc
    35041 tcgtcgtgga cgtgttgaag gtatggaagc tcgcgctggc ggccaacaag ttgttcgtgc
    35101 gatggttcca cttgctgaaa tgtttggtta tgctacaact cttcgttctg ctactcaagg
    35161 tcgtggtaca tttacaatga catttgacca ctacgaagat gtaccaaaat cagtacaaga
    35221 agaaatcatt aagaaaaacg gcggaaaagc tgaataattt cttaaaaccg gatagtcctg
    35281 caaagagatt atccaaagag actatatttt taatatagtt tcgtgtaaaa taattatcga
    35341 tgatatgggc atgtggtgta ccttgtgtac atcatatacc tatcagacaa ataaaaaata
    35401 tattgtattt ttaggaggac attttaaaat ggcaaaagaa aaatttgacc gttctaaacc
    35461 acacgttaac attggtacta tcggacacgt tgaccatggt aaaactacat taacagctgc
    35521 aatcacaact gtactatcta agaaaaacgg cggccaagct atggcttacg atcaaatcga
    35581 tggtgctcca gaagaacgcg aacgcggaat cacaatctca acagctcacg ttgagtatga
    35641 aacagataca cgccactacg ctcacgttga ctgcccagga cacgcggatt acgttaaaaa
    35701 catgatcact ggtgctgctc aaatggacgg agctatcttg gtagtttctg ctgctgacgg
    35761 cccaatgcct caaactcgtg aacacatcct attgtctcgt caagttggtg ttccttacat
    35821 cgttgtattc ttgaacaaag tagacatggt tgatgacgaa gaattactag aattagttga
    35881 aatggaagtt cgtgacctat taacagaata cgaattccct ggtgacgatg ttcctgtagt
    35941 tgctggatca gctttgaaag ctctagaagg cgacgcttca tacgaagaaa aaattcttga
    36001 attaatggct gcagttgacg aatacatccc aactccagaa cgtgacaacg acaaaccatt
    36061 catgatgcca gttgaagacg tgttctcaat tactggacgt ggtactgttg ctacaggtcg
    36121 tgttgaacgt ggacaagttc gcgttggtga cgaagttgaa gttgttggta ttgctgaaga
    36181 aacttcaaaa acaacagtta ctggtgttga aatgttccgt aaattgttag actacgctga
    36241 agctggagac aacattggtg ctttactacg tggtgttgca cgtgaagaca tccaacgtgg
    36301 acaagtttta gctaaaccag gtacaatcac acctcataca aaattctctg cagaagtata
    36361 cgtgttgaca aaagaagaag gtggacgtca tactccattc ttcactaact accgtccaca
    36421 attctacttc cgtacaactg acgtaacagg tgttgttgaa ttaccagaag gaactgaaat
    36481 ggttatgcct ggcgacaacg taacaatgga agttgaatta atccacccaa tcgctatcga
    36541 aaacggtact aaattctcaa tccgtgaagg cggacgtaca gttggtgccg gtgtcgttac
    36601 agaaatcaaa gcttaattca cttaagtttt aaagtaaagc aacatttatt cggacgtaat
    36661 cgctcggaac gaaggtctta ggatctttgt tccgagcttt tttatttatt gcaggatcag
    36721 gaaaaaagac aggagtatta taaatagaag aaacacgaaa taaaagagtc agtattttct
    36781 aaatgaaact ttatgaaaac aaaatgtttt ttacaagaaa aagccttgct ttgtgagttt
    36841 atatatatta taatgacaaa ggtgcgttta ctttagtgaa ttgcacagac gtaatcagaa
    36901 tgatttcgtc ggctaagaaa cgagaggttg cgacacgccc ggacgctttg ccacgaacga
    36961 gcgtgacgga aattttcgtg gagctatgtc tacttttcaa aataggcgaa ggagggaaca
    37021 agatggcaaa acaaaaaatt cgtatccgtt taaaagcgta tgaacaccgt attttagatc
    37081 aatcagcgga taaaatcgtg gaaactgcaa aaagaactgg agctagcgtg tctggtccaa
    37141 ttccattacc aactgaacgc agtctttaca caatcatccg tgcgactcat gaatacaaag
    37201 attcacgcga acaattcgaa atgcgtacac acaaacgtct tatcgacatt gtgaacccaa
    37261 caccaaaaac tgttgatgct ttgatgaagc tagacttacc atctggtgta aacatcgaaa
    37321 tcaaattata aaactaaaac aaaaataatg gaggtgtact catgaccaaa ggaatcttag
    37381 ggaaaaaagt gggaatgaca caaatcttca ctgaatctgg tgaattaatt ccagtaactg
    37441 ttgtagaagc tactccaaac gtagtactac aagtgaaaac aatggaaacg gatggctacg
    37501 aagctattca agttggttac caagatatgc gtgaagtttt atcaaacaaa cctgcgaaag
    37561 gtcatgttgc aaaagcaaac acggctccta agcgcttcat tcgtgaattc aaaaatgttg
    37621 agctaggaga atatgaagta ggaaaagaaa ttacagtaga tgttttccaa gcaggagaca
    37681 ttattgatgt aacaggtact acgaaaggta aaggattcca aggggttatc aaacgccacg
    37741 gacaaagccg cggaccaatg gctcacggtt ctcgttacca tcgtcgtcct gggtcaatgg
    37801 gtccagttgc acctaaccgt gtatttaaaa acaaacgtct tgctggccgt atgggtggca
    37861 accgcgtaac tatccaaaac ttggaagttg tacgtgtcga tgcagaaaga aatgttatct
    37921 tgatcaaagg taatgttcct ggagctaaaa aatctttaat tactatcaaa tcagctgtga
    37981 aagctaaata attgtaggaa gaaaggagga actaaggaat gccgaatgta gcattattca
    38041 aacaagatgg aagccaaaac ggtgaaatca cacttaacga agaaatcttc ggaattgaac
    38101 ctaatgaaag tgttgtttac gatgcaatcg taatgcaacg tgcgtcatta agacaaggaa
    38161 cacacgcggt taaaaaccgt agcgctgttc gcggcggcgg acgtaaacca tggcgtcaaa
    38221 aaggaacagg tcgtgcacgt caaggatcta tccgctcacc acaatggcgt ggaggtggcg
    38281 tagtctttgg accaacacca cgttcttaca gctacaaact tcctaaaaaa gttcgtcgtt
    38341 tagcaatgaa atctgtattg tcagaaaaag ttgctgaaaa caacttggta gcaatcgaag
    38401 gcttgaactt cgacgcacca aaaacaaaag aattcaaaca agttcttgct aacttatcta
    38461 tcgactctaa agtattggtt gttctagaaa aaggtaacga ctttgctgct ttatcagcac
    38521 gtaacttacc aaacgtttct gtagtaactt ctgataatgt gagtgtgcta gacgttgtat
    38581 caaatacaaa agtgttagca acacaaactg ctcttactca aattgaggag gtgcttgcat
    38641 aatgaactta ctagacgtaa tcaaacgccc agtgatcact gaaaaatcaa tgcttgccat
    38701 ggatgacaag aaatacactt ttgaagtgga cactcgcgca aacaaaactt tagtaaaaca
    38761 agcggtagaa gctgcttttg acgttaaagt caaaaacgtg aacatcgtga acgtacgtgc
    38821 gaaattcaaa cgtatgggca aatatgcagg atatacaaaa aaacgtcgca aagcgatcgt
    38881 tacattgact gaagattcaa aagaaatcca attattcgaa gctgctgaat aagcactaat
    38941 agataactca ttaaattagg agggaaaaac gtggcgatta aaaagtacaa acctacctca
    39001 aatggtcgtc gtaacatgac aggttctgat tttgctgaaa tcacaacatc aacacctgaa
    39061 aaatcattgt tacaaccatt gaaaaaccat gctggacgta acaacaacgg ccgcatcact
    39121 gtacgtcatc aaggtggcgg acacaaacgc caatatcgcg tgatcgactt caaacgtaac
    39181 aaagataacg ttgttgcaac tgttcaaacg atcgaatatg atccaaaccg ttcagctaac
    39241 atcgcgttag tacactatga agatggagtg aaagcttaca tcttagcacc taaaggacta
    39301 gaagtgggta tgaaacttgt ttcaggtcca gaagcagata tcaaagtcgg aaatgctctt
    39361 ccattagaaa acattccagt tggtactgtt atccacaaca ttgaaatgaa acctggtaaa
    39421 ggtggacaat tgatccgttc tgctggtaca agtgctcaag tacttggtaa agaaggcaaa
    39481 tacgtattga tccgcttgaa ctctggtgaa gttcgtatga tcttagctgc atgccgtgct
    39541 acaatcggtt ctgtaggtaa cgaacaacac gaattaatca acatcggtaa agctggacgc
    39601 tctcgttgga tgcgtaaacg cccaactgta cgtggtagcg taatgaaccc taatgatcac
    39661 ccacacggtg gtggtgaagg taaagctcct atcggacgta aagcaccagt ttctccttgg
    39721 ggtcaaccag ctcttggtta caaaactcgt aacaaaaaag ctaaatcaga caaacttatt
    39781 gttcgtcgtc gcaaaaataa ataattactt tgaccatgtg tcgcacattt tgagaggagg
    39841 ttcaccatgg gtcgtagttt aaagaaagga ccttttgtcg atgagcattt aatgaaaaaa
    39901 gttgaagctc aagcaggggt tgaaaagaaa aaagttatca aaacttggtc acgccgttca
    39961 acagttttcc caagttttgt tggatatacc atcgcagttt atgatggacg taaacatgta
    40021 ccagtttaca tccaagaaga catggtagga cacaaattag gtgaatttgc acctacaaga
    40081 acttatcgtg gacatgctgc tgacgataag aaaacgaaac gctaatttga ggggaggata
    40141 aatccaaatg gcagaacaaa tcacatcagc taaagcaact gcaaaaacag ttcgcacttc
    40201 acctcgaaaa gcccgtttag taattgacct tatcagaggt aaaagtgtcg cagatgcaat
    40261 ttcaatcttg aaattcacac caaacaaatc tgctggaatc attgaaaaag tattgatgtc
    40321 agcagttgcg aatgcagaaa ataactttga cttagatgtt gaaaacttgg tagtaagcga
    40381 agcttttgtt aacgaaggac ctacaatgaa acgtttccgt cctcgtgcaa aaggatcagc
    40441 ttctccaatc aacaaacgta caagtcatat cacggtagtc gtatcagaaa aataaggagg
    40501 gataatcagt gggtcaaaaa gtacatccaa ttggaatgcg tgtaggcatc atccgcgact
    40561 gggatgctaa atggtatgct gaaaaagagt atgctgagtt cttacacgaa gatttaagaa
    40621 tccgtaaatt tatttcaact aaacttgctg atgctgctgt atcaacagtt gaaatcgaac
    40681 gcgcaacagg tcgcgtaaac atttcaattc acacagctaa accaggtatg gttattggta
    40741 aaggcggttc tgaagtcgaa agcctaagaa aagaattaaa caaattaact ggtaaaagaa
    40801 tccatatcaa tatcgtggaa atcaaaaaac cagatctaga tgcaaaatta gtaggtgaag
    40861 gaatcgcacg tcaattagaa aaccgtgttg ctttccgtcg cgctcaaaaa caagccatcc
    40921 aacgctcaat gcgtgctggc gctcaaggga tcaaaactca agtatctggt cgtctaaacg
    40981 gagcagatat cgctcgttca gaaggatact cagaaggaac tgttcctctt catactttac
    41041 gtgcggacat tgattacgca tgggaagaag cagatacaac atacggaaaa ctaggagtta
    41101 aagtgtggat ctatcgtgga gaaattcttc caactaaaaa aaacactgag aaaggaggga
    41161 aataatcatg ttagtaccta aacgtgtaaa acaccgtcgt gaattccgcg gaaaaatgcg
    41221 cggggaagct aaaggcggaa aagaagtagc attcggtgaa tacggtttgc aagctgttga
    41281 ttcacattgg atcacaaacc gccaaatcga agctgctcgt atcgcaatga ctcgttacat
    41341 gaaacgtggt gggaaagtat ggattaaaat tttccctcac aaatcttata ctgccaaagc
    41401 aattggggta cgtatgggtt ctggtaaagg ggcacctgaa ggatgggttg caccagtaaa
    41461 acgtggtaaa atcatgtttg aaatcgcagg cgttcctgaa gaagtagctc gtgaagcgtt
    41521 acgtctagct tctcacaaat taccaatgaa aactaagatc gtaaaacgtg aggaaatggg
    41581 tggtgaatcg aatgaaggtt aaagaaatca gagaattaac cactgccgaa atgcttgatc
    41641 aagaaaaaca attaaaagaa gaattgttta atcttagatt ccaattagca acaggtcaat
    41701 tagaaaacac tgcacgtatt aaagaagtac gtaaatcgat tgcacgcatc aaaactgtgt
    41761 tgcgtgaaca agctaagtaa ttatggaagg aggccattaa gcgtatgact gaaggaagaa
    41821 atcaacgcaa agtttatcaa ggtcgcgtgg tttcagacaa aatggataaa acaattaccg
    41881 ttgctgtcga aacaaagaaa aaccacccta tctatggcaa acgcatgaac tattctaaga
    41941 aatacaaagt gcatgatgaa aacaacacag caaaagttgg cgacatcgtg agaattatgg
    42001 aaactcgtcc attatcagct acaaaacgtt tccgtttgtt ggaagtagtc gaagaagcag
    42061 ttattatcta ataacacgag attttcctat atagattgaa tgcaaaatct gaaaggagga
    42121 tacacaacgt gatccaagca gaaagtcgtt taaaagtcgc tgataactca ggcgcacgtg
    42181 aaattttgac gatcaaagtc cttggtggat ctggtcgtaa aactgctaac atcggtgatg
    42241 tgatcgttgc tacggttaaa caagcaacgc caggtggggt tgtcaaaaaa ggtgacgtcg
    42301 ttaaagccgt tatcgttcga acaaaatcag gagctcgtcg tacagacggt tcatatatta
    42361 aatttgatga aaatgctgca gtgattattc gtgatgataa aagccctcgt ggaacacgta
    42421 tctttgggcc agttgcacgt gaactacgtg aaaacaactt catgaagatc gtttcactag
    42481 caccagaagt tttataatct tgagacactt atcaaaggag gtgcgaaaca gttatgtttg
    42541 ttaaaaaagg cgataaagtt aaagttatca ctggaaaaga caaaaacaaa gaaggcgttg
    42601 tactagcagc gttcccgaaa aaagataaag ttattgtcga aggtgtaaat gtcgttaaaa
    42661 aacaccaaaa accttctcaa gctgctcctc aaggtggaat tgttgagatg gaagcgccaa
    42721 ttcatgtttc taacgtgatg gtggttgact ctactggtgt agctggccga gttggctaca
    42781 aagaagtaga cggcaaaaaa gtccgtgttt ctaaaaaaac cggtgaagtt ttagataaat
    42841 aaaagtttaa ggaaggaggg tcttactgaa tgaaccgcct aaaagaaaaa tatcttaaag
    42901 aagtaactcc atcattgatg gaaaaattta actatagctc tgttatgcaa acacctaaag
    42961 ttgaaaaaat cgtcatcaac atgggtgttg gtgatgcggt atcaaacgct aaaaacttag
    43021 ataaagcagt tgaagaatta actttgatca ctggtcaaaa accaatgatt acaaaagcta
    43081 aaaaatcaat cgctggattc cgtttacgtg aaggaatgcc aattggtgca aaagttacat
    43141 tgcgcggaga aagaatgtac gaattcttag acaaattggt ttctgtttca ctaccacgtg
    43201 tacgtgactt ccatggtgta agtaaaaaag cctttgacgg tcgtggaaac tatactttag
    43261 gtattaaaga acaattgatc ttcccagaag tagattatga tttagtagat aaagtacgtg
    43321 gtatggacat cgttattgta acaacagcaa actctgatga agaatctcgt gagttgttga
    43381 cacaattagg catgccattc caaaaataat taaaggaggc gaactacgtg gctaaaaaat
    43441 caatgattgc taaaaacaaa cgtcctgcaa aattttcaac acaagcttat actcgttgcg
    43501 aacgttgcgg acgtccacat tcagtttatc gtaagttcca tctttgccgt atttgcttcc
    43561 gcgaacttgc ctataaaggt caaattcccg gcgtgaagaa agctagctgg taaaaagtaa
    43621 attcgcataa gaaggaggta aaagatcaat ggtcatgaca gatccaattg cagattttct
    43681 aactcgtatc cgtaacgcaa acatggttaa acatgagtct ttagaagtac ctgcatcaaa
    43741 aattaaacgt gacatcgctg aaatcttgaa acgtgaaggt ttcgttcgtg atgttgaata
    43801 catcgaagat gacaaacaag gcgtgatccg tgttttccta aaatttggta aaaacggcga
    43861 acgtgttatc acaaacttaa aacgtatctc taaaccaggt ttgcgtgctt atgtcaaagc
    43921 tgacgaagta ccaaaagtat tgaacggttt aggtatcgca atcatttcga cttctgaagg
    43981 tgttgtcact gataaagaag ctcgtgaaaa aaatatcggc ggcgaagtta tcgcttacgt
    44041 atggtaatca agtagaatct acaaggaggt gtctttaagt gagccgtatc ggaaataaag
    44101 tcgttgttat ccctgaagga gtaacagtta ctcaagacgg aaacaacgtt acagttaaag
    44161 gaccaaaagg tgaattgact cgtacttttt cagcagatat caaaatgaat atcgaaggaa
    44221 acgaagtaac tttcactcgt ccaaacgaca gtaaagaaat gaaaacaatt catggaacaa
    44281 ctcgtgcgaa cttcaacaac atggttgtag gtgtcagcga aggtttccaa aaagcgttag
    44341 aactaatcgg ggttgggtac cgtgcacaat tacaaggatc aaaacttgta ttgaacgttg
    44401 gttactcaca tccagtagaa atcacaccac cagctggagt aactgttgaa gtaccagcta
    44461 acacacaagt aattgttaaa ggtgcgaaca aagaagaagt tggcgaatta gctgcaaaca
    44521 ttcgtggaac tcgtcctcca gaaccttata aaggtaaagg tattcgttat gttggcgaat
    44581 atgtacgccg taaagaaggt aaaactggta aataatcgtt tagaaaaatt gcatagaagc
    44641 cagcagcagg aaaaaggcat ttggctgaag tttaccttca aaaaaataca tttttacttg
    44701 tgccgcagct tctatttttc gaaacgtatt tactgcttga aatagtagta caataaaaat
    44761 aaagaggtga caattgtgat tacaaaacca gataagaaca aaacacgtca aaagagacat
    44821 cgtcgtgtac gtaacaatat ctctggtact gctgagcgcc cacgcttgaa cgtttttcgt
    44881 tctaacaaaa acatctacgc tcaaattatt gatgacgtag cgggtgtaac gctagcaagt
    44941 gcctctacct tggataaaga aatttcaggt ggaacaaaaa cagaagcagc acaagctgtc
    45001 ggtaaactag ttgctgaacg tgcagctgaa aaaggcatta aagtagtagt ctttgaccgt
    45061 ggtggatacc tttaccatgg ccgtgtgcaa gctttagctg aagctgctcg cgaaaatgga
    45121 ctagaatttt agaagaagga ggaataccat tcatggttta tatcgatcca aaacatttgg
    45181 aattagaaga ccgcgttgtt gcaattaacc gtgtaacaaa agttgttaaa ggtggacgtc
    45241 gtctacgttt tgctgcttta gttgttgtcg gtgacaaaaa cggacacgta gggtttggta
    45301 caggtaaagc tcaagaagtt cctgaagcaa tccgtaaagc aattgaagat gcgaagaaaa
    45361 acttagttga agtacctatg gttggttcaa caatcccaca cgaagtaatc ggtgctttta
    45421 gtggtggtag aatcctaatg aaacctgctg tagaaggttc tggggttgct gctggtggac
    45481 cagttcgtgc cgtattagaa ttagctgggg tagcagatat cacttctaaa tctttaggct
    45541 caaatacacc aatcaacgtt gttcgcgcaa cagttgaagg tttgaaacaa ttgaaacgtg
    45601 cagaagaagt tgcagaactt cgcggcaaat cagttgaaga attaatcgga taaggaggac
    45661 aacaataatg gctgaattaa aagttacttt aaaacgcagt attatcggac gtcctcaaaa
    45721 ccaacgcgat acagttaaag cgttaggtct tacaaagatt aacagttcag tggttaagcc
    45781 ttctaatgaa gcaattaaag gcatgatcaa tactgtttct cacctagtgg acgttgaaga
    45841 aatttaattt agaaaaatca taactagaac attaaggagg tgccaaacct atgaaacttc
    45901 atgaattaaa acctgctgaa ggttcacgcc aagtacgtaa ccgtgttggt cgtggtactt
    45961 catctggtaa cggaaaaact gccggacgcg gacaaaaagg acaaaaagct cgttcaggcg
    46021 gcggtgtgcg tttaggattt gaagggggac aaacaccatt gttccgtcgt ttaccaaaac
    46081 gaggattcac aaacgtgaac cgtaaagact atgcagtcat taatcttgat gtattgaacc
    46141 gctttgaaga cggagctgaa gtaactcctg ttgctttagt tgaagctgga atcgtgaaaa
    46201 acgaaaaagc tggaatcaaa gtattagcta atggggaact aaacaagaaa ttaactgtga
    46261 aagcagcaaa attctctaaa gcagctcaag aagcaattga agcggctggt ggatcaatcg
    46321 aggtgatcta atgtttagac tattaaaaga tgcttttaaa gtaaaagaca ttagatcgaa
    46381 aatcctattt actgtatttg tgttgtttgt atttcgccta ggtgcacata ttactgtacc
    46441 aggcgtaaat gctgcttcat tgcaaaacct ttcttctttg ccatttttca acatgttgaa
    46501 cttggtaagt ggtagtgcga tgcaaaactt ttccattttc tcaatggggg tttcaccata
    46561 cattactgct tctatcgtca ttcagcttct tcaaatggac atcgtgcctc gatttgttga
    46621 atggtcgaaa caaggggaag ttggtcgtaa aaaactgaat caagcgactc gatatctgac
    46681 attagtattg gcatttatcc aatctgtcgg tatcactgct ggattcaatc aatacgctca
    46741 attaggtttc gtgaataatc ctaacgtagc aacttacgta acgatcggtt tgattctaac
    46801 agccggtacg atgtttgtta cttggctagg agaacagatc acagaaaaag gtatcggaaa
    46861 tggcgtatca atgatcattt ttgcaggtat catttctaga ttgcctgaaa gtatcagaga
    46921 aatttatgaa gattacttta taaatattga tccttcagac atatggaaat ctgctatttt
    46981 tgtggccatt ttactagtag cggtcttgtt gatcgtgaca ttcgtaacat ttttccaaca
    47041 agctgaacgc aagatcccga tccaatatac gaaacgcgta gctggcgcgc ctacaagcag
    47101 ctatctgccg ttgaaagtaa atgcagctgg agttattcca gttatctttg ctagttcgtt
    47161 tattgctacg ccaaatgctg ttttacaagc attgagcggt agattcggtt ctgaaaactg
    47221 gtacaaagtg atgatggaga tctttaacta taatacagca cctggtgcta cgatttatac
    47281 gattctgatc gttgccttca ctttcttcta cgcctttgtt caagtaaacc ctgagaaatt
    47341 agcggaaaac ttgcaaaagc aaggaagtta tataccaagc gtacgccctg gtaaggggac
    47401 tgaagagtat gtctcaagat tactgatgcg tttaagtaca gttggtgcag tcttccttgg
    47461 tttagtggca ttgcttccaa tcattgctca aatggtttgg gatcttccac aatcaatcgg
    47521 attaggcggt acaagcttac tgatcgttat cggtgtagct ttagaaactg cgaaacagtt
    47581 agaaggctta atgctgaaac gtaaatatgt tggattcatt gagtaagaaa gcgtgttgag
    47641 gtttcccctc aacacacgtt ctcacacatt tattaggagg gaaaacaatg aacctcattt
    47701 taatggggct gccaggcgca ggtaaaggaa cacaagctga aaaaatcatt gatgcttatg
    47761 gtattccgca catctcaaca ggagatatgt tccgcgcagc gatgcaaaac gaaacagctc
    47821 ttggcctgga agcaaagtct tatatggata aaggtgcatt agttcctgat gaagtaacaa
    47881 atggaatcgt gaaagagcga ctagctgaac cagatacaga gaaaggcttc ttattagatg
    47941 gctttccacg tacgctagat caagcaaaag ctctggacgc aatgctaaaa gatttgaata
    48001 aaaaaattga tgctgtcatc gatatccatg ttggtgaaga aatcttggtc gaacgtctag
    48061 ccggccgatt tatctgcagc aattgtggag caacttacca taaaattttc aaccctacaa
    48121 aagttgaaga cacatgtgat cgttgcggtg ggcatgaatt ctatcaaaga gaagatgata
    48181 aacctgagac ggttaaaaat cgtctggcta tcaacatcaa aaatagtgaa ccaatcttgg
    48241 cttattataa agaacaaggt ttgctaaaca ctattgatgg tgctcgtgaa atcgatgctg
    48301 tatttgcaga tgtacaaaaa atcattgaaa aatagcacga ttgcccgtag ccgacttgca
    48361 ttatgcagtt actcttgtca agttcaataa attatgatag aatatgtcag tccgacttct
    48421 agagaatcct ctagatgatc cattttgaga attttgaggt gggaactgca gtttccgcca
    48481 ttttatcgtg tgaaaatgcg aaacaagtac aaggaggtac tgtgcgtggc aaaagaagat
    48541 atgattgaag tcgaaggtac agtcgtcgaa actttgccga atgcaatgtt taaagttgaa
    48601 ctagaaaacg gacaccaagt tcttgctact gtttcaggta aaattcgtat gcattacatc
    48661 cgtatcttac ctggtgacaa agtaacggtt gaattgtctc catacgatct taaccgtggc
    48721 cgtattactt atcgctttaa ataattgtac tccgtaaaac tacaggaggt attatcatga
    48781 aagtaagacc atcagtaaaa ccaatgtgcg aacattgtaa agtaattcgt cgtaaaggac
    48841 gcgttatggt gatttgccca gcaaatccaa aacataaaca acgtcaagga taattggagg
    48901 tgctataaat atggctcgta ttgcaggagt agatattcct cgtgataaac gtgtagtagt
    48961 ttcacttact tatatctatg gtattggtaa cactactgct aaaaagatct tagctgatgc
    49021 tggtgtatct gaagatgttc gcgttcgtga attaacgaat gaacaaacag atgctatccg
    49081 tgcagaagta gataaattaa aagttgaagg ggatcttcgt cgtgaagtga acttgaacat
    49141 caaacgtttg atggaaatcg gttcttaccg tggaatccgt catcgccgtg gattgcctgt
    49201 tcgtggacaa aacacgaaaa acaatgcacg tactcgtaaa ggcccagctc gcgctatcgc
    49261 tggcaagaaa aaataattct taagtgaagg aggttaaaac ttcatggcag caaaaaaagt
    49321 gaatcgtaaa cgccgtgtga agaagaatat agaagcaggt attgcacata tccattctac
    49381 attcaataac actatcatca tgatcactga tactcacgga aatgcattag cgtggtcatc
    49441 agctggttca ttaggtttca aaggaagcaa aaaatcaact ccttttgccg ctcaaatggc
    49501 agcagaaact gctacaaaag cagcaatgga acacggatta aagactgttg aagtaacagt
    49561 taaaggacct ggttctggac gtgaagcagc aattcgttca ttacaagcta caggtttaga
    49621 agtgactgca attcgtgacg tgactccagt tcctcataat ggtgcccgcc ctccaaaacg
    49681 ccgtcgtgtt taatgagtgc cgctcatttt gagttttatc agtaacgtca ttgaacaaga
    49741 cacttttcgt tttgaaaggg gtaaagataa gaatgattga gttcgaaaaa ccaagaatcg
    49801 caaaaattga tgaagaaaaa gattatggca agttcatcgt tgaacctctt gaaagagggt
    49861 atgggactac tttagggaat tccctacgtc gtattttatt atcttctttg ccaggtgctg
    49921 ccatcactaa tattcaaatc gatggtgtac tgcatgaatt ctctaccatc aaaggtgtta
    49981 gagaagacgt cactcaaatc atcttgaaca ttaaaggctt agcgctgaaa atgtatggcc
    50041 aagaagaaaa aacccttgaa atcgatatta ccggacctgc tacagtaact gctggcgata
    50101 ttatcgttga tagtgatgta gaaattctta acaaagatat gtacatctgt agtgtctctg
    50161 aaggagctac gttccatgct cgcttaacag tgaaacctgg acgtggttat gttcaagcag
    50221 atgaaaataa aaaagaagat atgccaattg gcgttcttcc agtcgattca atctacacac
    50281 ctgttcgtcg tgtgaactat caagttgaga acacacgtgt tggacaccgt gaagattttg
    50341 ataaattgac gatggagatt tggacagatg gttcaattga accgttggaa gcaatgagtt
    50401 tgtctgcgaa aatcatgact gaacatttgg atatttttgt gaacttaact gatgaagcaa
    50461 aaaatgctga aatcatggtc gaaaaagaag aaacacaaaa agaaaaaatg ttggaaatga
    50521 cgatcgaaga gttagacttg tctgttcgct cttacaattg tttgaaacgt gcaggaatca
    50581 atactgtaca agaacttaca aataaatctg agcctgaaat gatcaaagtc cgtaacttag
    50641 gacgtaaatc attagaagaa gttaaagcaa aattgcacga cttaggttta ggtttacgta
    50701 aagaagatta aaacctttta cgaaggaggg aaaccaacgt gagttatcgt aaactaggac
    50761 gcacatctag ccaacgtaaa gcgatgttgc gtgatttaac aactgattta ttaatcaacg
    50821 aacgtattgt gactactgaa gctcgtgcga aagaagttcg ctcaactgca gaaaaaatga
    50881 tcactttagg taaacgcgga gatttgcatg cacgtcgtca agctgcggct ttcgtacgta
    50941 atgaagttgc cagcgtgcgt gaagaaaatg aggacatcgt cattgaatca gctttacaaa
    51001 aactgttcaa cgatattgca cctcgttacg cagaacgtca aggcggatac acacgcattt
    51061 tgaagacaga accaagacgc ggtgatggtg caccaatggt tgtcttagaa cttgtctaaa
    51121 atcacactaa taacatcact ttatagatga ttcttttaga gtgttatgat gttggaagat
    51181 atttttccga gtctagctca gcgctgctcc tcaagcgaat atcgcttggg gagtaagcac
    51241 tcatcataaa gtgttttttt ataccttcaa ttacctgtca tgacagatat gtttgaaggc
    51301 ataaaaaaac attttaagcg agaaataatt gaaaattttg tctttttttg atagtgttag
    51361 taggaacttt aggatgaaga aggagtaatc atggagccaa ttattgaatt agaaaagata
    51421 aattataaat accagccaga tgatcttcgc cccgcattga aagatgtctc ctttacaatt
    51481 gataaaggtg agtggatcgc tattattgga cacaatggtt caggaaaatc gacacttgcc
    51541 aaaacgatca atggattgct tctgccagaa tcagggatcg tgaaagtggg aaatcaaata
    51601 ttggatgaag aaaatatttg gacgatccga cagatggttg gaatggtttt tcaaaatcca
    51661 gacaatcagt ttgttggttc gacagtagaa gatgacgttg cttttggtct tgaaaatcaa
    51721 gggattccca gagaagaaat gctagtgcgt gtgaaagatg cacttgagaa agttagaatg
    51781 gctgagtttg cttcacgcga gcctgctcgt ttatcaggag ggcaaaaaca acgtgttgcc
    51841 attgccggcg tggttgcctt acgacctgat atcattattt tagatgaagc aaccagtatg
    51901 ctagatccag aaggtcgtga agaagtgatc tctacgatca agaagatcaa agaagaaagt
    51961 caattgaccg ttatatctat cactcatgat attgatgaag cagctaatgc caatcggata
    52021 ctagtgatga gacaaggcga acttgtccgt gaaggtacac caaaagaaat tttttctgct
    52081 ggtcctgaac tgatcgactt aggtctagat ctaccatttc ctgaaaaact gaagagcgca
    52141 ctgaaagaac gtggggttga tgtgcccagt gaatatatga cagaagaaag gatggtggat
    52201 tggttatgga catccgtttt gaacaagtag acttcactta tcagccgaat acaccatttg
    52261 aacaaagagc cttatttgac atcaatatga cgatcaaaga aaacagttat actgcattag
    52321 tagggcatac cggaagcggg aaatcaacct tacttcagca tttgaatgcg cttgttaagc
    52381 caacaagcgg tacagtccat attggagaac gagatattca gccggatacg gataataaga
    52441 atttaaagcc catccgaaaa aaagttggca tcgtctttca gtttccagaa gcacagctat
    52501 tcgaagaaac ggtagcaaaa gacattgctt tcggtcctaa aaactttggt gtcagcgaag
    52561 aagaagcact agtcctagca aaagaaacat tagaacaagt tgggctggat gaaagctatt
    52621 tggaacgttc gccatttgaa ctttcaggag ggcaaatgcg tagagtagca atcgctggtg
    52681 tgcttgccat gaggccggaa gtacttgtat tggatgaacc aacggcagga cttgatcccc
    52741 agggtagaaa agaaatgatg gagatgtttt ggcgtcttca taaggaacag cagatcacta
    52801 ttgtattagt tacgcattta atggatgatg tagccaattt tgcagattat gtctatgtgt
    52861 tggaaaaggg acgaatcgtt aatagcgggg agccgcaaga ggtctttcaa aacattgaat
    52921 ggctaaaaga aaaacaacta ggcgtaccta ctgccaccga gtttgcagaa gaattaatgg
    52981 ctaaagggat gaactttgct accttgcctt tgacagctga agaattagca gacgctatcg
    53041 tccattatgc tggaggaaat gcccatgatg aataaattga tatttggtcg ttatatgcct
    53101 ggagattcct tgatccatcg attggatccc cgagctaaat tattagccag tttttatttt
    53161 atcggaatca tttttttagc aaataattgg gaaacgtacc ttttgttggc atttttcaca
    53221 ttactttctg tcttcttgtc aaaagtagat ttgaaatttt ttatccgagg cattcgccca
    53281 ttgatctggc taatcctctt cactgtagct ttgcaggtct tgtttacaag tggcggagaa
    53341 acttattgga gttggggtgt tttccatatc actgaatttg gtgtgatgaa cggcctcttt
    53401 attttctgtc gattcgtgtt gatcattttt atgtcgactc tactcacgct tactacaccg
    53461 cctttggaat tatcggatgc gattgagtac ttgcttcgtc cattgaaagc cgtacggttc
    53521 ccagtccacg aaatttcatt gatgctgtcg attgctcttc gttttgtgcc tacattgatg
    53581 gacgaaacag aaaagatcat gaacgctcag cgcgctcgcg gtgttgattt tggtgaagga
    53641 aacctagttc agaaaatgaa agcagtcatt cctttgctga ttcctttatt tgtcagcagc
    53701 ttcaaccgtg cggaagatct tgcgactgct atggaagcaa gaggctacaa aggtggggaa
    53761 ggaagaacga aatatcgtgt attgcattgg cataatagag acacgatggt tatcattgct
    53821 tttgtattat taactgtgct actgatcttt ttgagaggat aaacgttcag tgggccgcta
    53881 tctattcttt tcttgctgat ctgtttgcaa gaaaggatgc gagcagtgta tgacaagaaa
    53941 tattagggtc tgtggcagac taaggtcaca ggcctctttc ttttatctga aaagaaagaa
    54001 cgaaaaaatt ttataaaaaa atcattattc cagataacct tttaggaaca aaggagagaa
    54061 aaacatggta cgttacaaag caatcattgc atacgacgga acaaatttta atggattcca
    54121 aaaacagcca aatgggcgta ctgttcaaga agaagtagaa aaaacattac aaaaaatggc
    54181 aaatggaaaa gaaatcacgg tctttggttc gggaaggaca gatgccggag tacatgcgat
    54241 tgggcaagta atccattttg attatccaga ggagcgtccg ttagaacgaa tgcgtttcgc
    54301 gctagatacc cagtcaccag aggatattgc tgtaagacaa gtagaaattg tttcagaaga
    54361 cttccacgca agatatttgg tcaaagaaaa gacgtatcaa tttcgagtgg atatagggaa
    54421 accacgcagt ccttttcgac gccattatgc aagttatttt ccttaccctc ttgatttgga
    54481 aaaaattcag cgggcgcttc ctgatttatt agggactcac gatttcacct ctttttgtgc
    54541 atcaggaagc tcgatagagg ataaagtacg tacgatctac gaggctaaga tggaggtaaa
    54601 tgaaacaaaa gacgaattgt tgtttacatt taggggaaat ggcttcttgt ataagatgat
    54661 acggatctta gtaggaacgc ttttgaaaat tggcaatggc cgattgcctg aagatagtat
    54721 cccagatatt attgcgaaaa aagatcgtaa tgcagcagga cctacagcac atcctgaagg
    54781 actttatttg tatgaagtga aatatgaata agaggttgtg acagaagtgg tcagcttcaa
    54841 gaaataagaa ggaatttacg aaaattactt ctcaaaattt tgcaaaattt cggcttattt
    54901 tcgaaggagc tacttctgga acaccgtgaa tcagaggttg tgaaaaagct gccctgcatc
    54961 aagtaataag aacaaccaaa caaaaatagc tcgtcatatt tttcgtttgg ttgggcttat
    55021 taccgcagat gcaagctttt gaacaccgtt taaggaagag gttgtgaaat cagcgttttg
    55081 acctgagtat tagagaaaca aacggaaaaa tagttcctca tattttgccg tttgttgagc
    55141 taataccgaa ggtcagctga ttgaacaccg tttaagaaag aggtcgtgag cctgtcattt
    55201 aactctgagt cacaagtaac aatttcaaaa aacagcttct catctttgat gaatatcgtg
    55261 acttgtggac gaggcgttga taagtgaatc atctttttgt tacctatttt ttctgtaacc
    55321 aaaaaacgat ggaacgttgt tttgattgcc cttaatgagg acagtcggaa caggtttgtc
    55381 atttttatat ttaaatggca caaatttttc taattatttg tcatttagcg ctgaaaattt
    55441 ttgctattta tctaaaaaag tgataactac ttaagatgaa gcagaatatt tacgccatac
    55501 ggcatacaac cgcgaaaaat ataaaaaaaa gaaaacgatt gaacgcgttt ttgcagtcgc
    55561 aaaggaaaag catggaatgc gctacatcaa gtatcgagac ttggaaaaca atcaggtgta
    55621 tacgctgatt gtttttgctg caatgaatct gaaaaagttg tccacttggc agttggaaca
    55681 tatgtcttca tatcttttat tatacaaaaa tagcaaaagc accagtctac actcttagta
    55741 aagaggaaac tgatcctttt gtctacattc ttaaagtact taaactaagt actttatttt
    55801 actctttagg attgatacag tagcatctat ccctttatta ataatctttt atttttttaa
    55861 ataaagatgt tgtctccatc ttcaggcact aaaacttttt cggaaattcc tttttcttta
    55921 ttgaaagact ttaattcttc tcttgacagt ccccaatggt ttacagcttc catatgaacg
    55981 gcaataattg tggaatctgg tattgcttta tgcaattcat ataaatcgtc tttccccata
    56041 ataagagatt ctccaactaa aaaatgatta tctccagcat ttgctactat gatttctgga
    56101 ttatactgat caatagtttg tttaacagct tcataccaaa ctgtatctcc tgtaaagtat
    56161 agtgtcttct cagtcgaatg tttgaaaaca ataccgcaaa cattacctac ataattcaag
    56221 atttctcctc tgccatgttt gccttttgtt ttaaccaatt gtatagattc aaaaactgtg
    56281 tcttctcgta gtacctccac atttttaaaa ccatatagtc gaatttcatt cgcatcattt
    56341 tcatcttgca caaataattt tatttcttta ggtaggacct ctttcgctat atcgtcccaa
    56401 tgatctagat gtaaatgtgt tacaataaca gcatcaatac cgttgataat atcttcgact
    56461 ggcattggca aatcaactag aggattcatt tgatcttttc ttggtgatgg aaaaggacct
    56521 ttcgaaataa atggtggaag tgttcctttt tccgctaaca ttggatcaat taaaaatttt
    56581 ttacctccat agtctaagat agctgttgca ttacgaatgt gatgtatatt cataaacgtt
    56641 gtctcctttt tgttgatatg aaatattttt agtataattc aattccatac aataaataaa
    56701 ccgaacaaaa aaagtctttt actattttta cttaatttat gaaaggttgt ttaccatgtt
    56761 agaccaaaca gatataaata tcattgagga actatcaaaa aatagtcgaa tcacaatgaa
    56821 agaacttgga gaaaaagtac atttgactgg acccgctgtc tcggcgagag tgacaaaact
    56881 agaggaaagt ggagttattg aaaattatac agtaaaatta aatatggaaa agctagggtt
    56941 ttcgattcac gcttttttaa ttataattac gcaaaattta aatcataaac cctatttatc
    57001 atttattaaa aatcatgaaa aattcttgat tagaaattat aagattagtg gagggggctg
    57061 ttatcttttg gaatgtagat ttacttcaaa aaaatcaatg aacagctttt tggaacagct
    57121 taatgaatat gcgaattata aattatctat tgttatagat taataataaa actagcagat
    57181 ggtaaaaata ctaatatgcg agacacacat tcaaccataa ctatataact tatcaattta
    57241 aaactaaact gatggaaaca agtaaggcaa aaacatttat attttgccct acttattttt
    57301 ttaattaaat tcattgatga ttcatattta gaaaattcta tgaaggccaa atgagtatcc
    57361 tgtcactttt ttagataaat agcaaaaatt ttcagcgtta aatgacaaat aattagaaat
    57421 atttgtgcca tttaaatata aaaatgacac caagtatatc atgaacgcac aaaaagacca
    57481 acagggtata ccctgttggt ctaaataa
//
LOCUS       DACBYO010000008        51126 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.008, whole genome shotgun sequence.
ACCESSION   DACBYO010000008 DACBYO010000000
VERSION     DACBYO010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.008"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            212..604
                     /locus_tag="IVD26_000465"
     CDS             212..604
                     /locus_tag="IVD26_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP6078469.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="IVD26_000466"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="IVD26_000466"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAP6078470.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="IVD26_000467"
     CDS             3165..4775
                     /locus_tag="IVD26_000467"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAP6078471.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGAVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="IVD26_000468"
     CDS             5067..5936
                     /locus_tag="IVD26_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAP6078472.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="IVD26_000469"
     CDS             6101..7372
                     /locus_tag="IVD26_000469"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP6078473.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /locus_tag="IVD26_000470"
     CDS             7369..8664
                     /locus_tag="IVD26_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAP6078474.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="IVD26_000471"
     CDS             8763..9026
                     /locus_tag="IVD26_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAP6078475.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="IVD26_000472"
     CDS             9471..9920
                     /locus_tag="IVD26_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6078476.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="IVD26_000473"
     CDS             9977..11395
                     /locus_tag="IVD26_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6078477.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="IVD26_000474"
     CDS             11395..12255
                     /locus_tag="IVD26_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAP6078478.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="IVD26_000475"
     CDS             12429..13202
                     /locus_tag="IVD26_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP6078479.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="IVD26_000476"
     CDS             13349..13714
                     /locus_tag="IVD26_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAP6078480.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="IVD26_000477"
     CDS             complement(13862..15070)
                     /locus_tag="IVD26_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6078481.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="IVD26_000478"
     CDS             complement(15089..15367)
                     /locus_tag="IVD26_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078482.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="IVD26_000479"
     CDS             15560..16216
                     /locus_tag="IVD26_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP6078483.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="IVD26_000480"
     CDS             complement(16658..17455)
                     /locus_tag="IVD26_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAP6078484.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="IVD26_000481"
     CDS             complement(17452..18636)
                     /locus_tag="IVD26_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAP6078485.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="IVD26_000482"
     CDS             complement(18661..19908)
                     /locus_tag="IVD26_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAP6078486.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="IVD26_000483"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="IVD26_000483"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAP6078487.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="IVD26_000484"
     CDS             21888..22202
                     /locus_tag="IVD26_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAP6078488.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="IVD26_000485"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="IVD26_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAP6078489.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="IVD26_000486"
     CDS             22887..23531
                     /locus_tag="IVD26_000486"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAP6078490.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="IVD26_000487"
     CDS             23546..23875
                     /locus_tag="IVD26_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078491.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="IVD26_000488"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="IVD26_000488"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAP6078492.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="IVD26_000489"
     CDS             24863..25687
                     /locus_tag="IVD26_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAP6078493.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="IVD26_000490"
     CDS             25680..26027
                     /locus_tag="IVD26_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAP6078494.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="IVD26_000491"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="IVD26_000491"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAP6078495.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="IVD26_000492"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="IVD26_000492"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAP6078496.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="IVD26_000493"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="IVD26_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAP6078497.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="IVD26_000494"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="IVD26_000494"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAP6078498.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="IVD26_000495"
     CDS             31684..32451
                     /locus_tag="IVD26_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6078499.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="IVD26_000496"
     CDS             32441..34483
                     /locus_tag="IVD26_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6078500.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="IVD26_000497"
     CDS             34764..34913
                     /locus_tag="IVD26_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAP6078501.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="IVD26_000498"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="IVD26_000498"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAP6078502.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="IVD26_000499"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="IVD26_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAP6078503.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="IVD26_000500"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="IVD26_000500"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAP6078504.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="IVD26_000501"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="IVD26_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAP6078505.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="IVD26_000502"
     CDS             39330..40412
                     /locus_tag="IVD26_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAP6078506.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="IVD26_000503"
     CDS             40412..41215
                     /locus_tag="IVD26_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAP6078507.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="IVD26_000504"
     CDS             41285..42025
                     /locus_tag="IVD26_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP6078508.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="IVD26_000505"
     CDS             42036..43040
                     /locus_tag="IVD26_000505"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAP6078509.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="IVD26_000506"
     CDS             complement(43085..44929)
                     /locus_tag="IVD26_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078510.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45140..45658
                     /locus_tag="IVD26_000507"
     CDS             45140..45658
                     /locus_tag="IVD26_000507"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP6078511.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45786..46469
                     /locus_tag="IVD26_000508"
     CDS             45786..46469
                     /locus_tag="IVD26_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAP6078512.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46778..46851
                     /locus_tag="IVD26_000509"
     tRNA            46778..46851
                     /locus_tag="IVD26_000509"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46812..46814,aa:Arg,seq:tct)
     gene            47010..47369
                     /locus_tag="IVD26_000510"
     CDS             47010..47369
                     /locus_tag="IVD26_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAP6078513.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47492..49123
                     /locus_tag="IVD26_000511"
     CDS             47492..49123
                     /locus_tag="IVD26_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAP6078514.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49185..49826)
                     /locus_tag="IVD26_000512"
     CDS             complement(49185..49826)
                     /locus_tag="IVD26_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP6078515.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            50108..50416
                     /gene="rplU"
                     /locus_tag="IVD26_000513"
     CDS             50108..50416
                     /gene="rplU"
                     /locus_tag="IVD26_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAP6078516.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50443..50787
                     /locus_tag="IVD26_000514"
     CDS             50443..50787
                     /locus_tag="IVD26_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAP6078517.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50800..51093
                     /gene="rpmA"
                     /locus_tag="IVD26_000515"
     CDS             50800..51093
                     /gene="rpmA"
                     /locus_tag="IVD26_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAP6078518.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
BASE COUNT        16403 a         8856 c        10660 g        15207 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggagcag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca
    45061 tttttacagc tataatttga aaaaatttat cgttattata tgattaagaa ggattgaata
    45121 aagaaagaag ttgaaaacga tacctgatta caaaaaaata acttttataa gttctataac
    45181 gttgattata tttttaattc ttattcttct cgtcgtcttg gttccccgaa tttttggttt
    45241 gactccttat attattgagg acaaagaaat gagtccatat tatgcacaag gaaatctgat
    45301 atatgtacga ccgaaaaata caaatgagat tttagtcgga gatattatta catattatga
    45361 aaattcagga aaaaaaatct cgacgcgtcg cgtaatagcc gttgaaaaca accacgaaga
    45421 tttttataca aaagctgata caaagactta tattgagcct ggagtagtaa aaaagagaaa
    45481 tattatcggt agtcccatct ttcagattcc atatattgga ctagtccttt caaaaacggc
    45541 atttgcatgg attcaggggt tattctttac gattgctttt tgcctaacag gaatcacagc
    45601 atggaatacc tttgtagagt tgaaaaagaa gcggagacga acacagaaat ttttgtaaga
    45661 atgttaaaaa cataaatgta ttccagagat ccaacgactc ttctgaacat gaaacacgag
    45721 aaaacactca tgcagcttgt agatttagtc agttgttcgt ataatgtgtg aagaggagga
    45781 gtagtatgcg caatgaaatg atgcatcgtc ctgtagtcaa agaagaacta ttggatttta
    45841 tgcgtaccca gcaaaaaaaa ttaccgggtg agctaggcaa actggaagaa gaagctcatg
    45901 tagcagaagt accagttatt ccccatgaaa cagttgtatt tttgaaattt ttacttggac
    45961 agcttcagcc tgaacgaatc ttggagatcg gagcagctat cggtttttca tcaagtgtca
    46021 tggccacgac aatcggagaa aacgctcatg ttacgacaat tgatcgtttc gatgtcatga
    46081 tcgagaaagc taaaaaaaac tatgaacgtc taggactgac agataaagtg actttgcttg
    46141 aaggtcaagc agcagatatc ttgccggagt tgtctggtcc gtatgacttt atttttatgg
    46201 atagtgcaaa atcaaaatat attgaatttt tacctgaatg cttacgtttg ttaagaaaag
    46261 gtggcgtttt gatggtagat gacatcttcc aaggaggaac gatcttgctc ccagatgaag
    46321 agattccccg tggcaaacga gctatccatc gtaaattaaa tgaatttctt cgtgttgtga
    46381 tggatcatcc cgatttgaca tcgacaatct tgccattagg tgatggtgtg atcttaatga
    46441 caaaggaatc agaaacaatc gagttgtgat acatgattat ggcagcctgt agataatcga
    46501 ttgaatcgag ggctcaattc gaacttgatg taaaagtttc tatatttgta agtcaattaa
    46561 aggatacagg aaatctaaat aaacaggagt agcatgaagt caatgtagct cctgttttca
    46621 attgataacc ttagaacagc tgaaggagaa tgtctcgttt taaaagattg atttagtagt
    46681 tgggccaaaa taattcatta tttgctaatt aaataactat ttcgtattga cagaagcaat
    46741 ttaattatct ataattattg atgttccgct gattcttgtc atagtagctc agctggatag
    46801 agcatccgcc ttctaagcgg acggtcgggg gttcgaatcc ctcctgtgac gctaaaaaac
    46861 cgttagaaac tgaggtttct aacggttttt ctttgttttt tgtgccaata ttgtttgttt
    46921 tcaaaggcaa ataaaataaa aaaacatcct tatcgagtac aattataagg agcaaaaaaa
    46981 taaaactcat cagaaaagag gaagaagata tgacgatact atctagaatt ttagtgactc
    47041 tagttgcaat tgaatttttt tatatcatgt atatcgaaac ggtgagaact gattctgaca
    47101 cgacaagtag ggtttttaaa atgagtaaag aagagttaag cagaaaatct gttcaaacat
    47161 tgtttaagaa ccaaggagtg tacaatggac tattaggagt gggactactt tatggagctt
    47221 atctttcttc cgcatctaaa gaaatcacaa gtatgctatt aatatctatt ttttttgttg
    47281 cattatatgg cagtttgact agcgatcgtt ggattttact caaacaaggt gggctagctc
    47341 tgttggcatt gctttctatt ttcttataaa tatagaaaaa ataagaattt atctaacagg
    47401 aaactttgtg aaaaatatta ctttatctca tgaaatatga tattctaatg aatggtattt
    47461 tagaaaattt catgaaaaag gagttagata ggtgttcaaa aattatgttt cctcactaaa
    47521 aaaagaattt tcaggttatg atctttcaag atttcagaaa gatcttttgg ctgggatcac
    47581 agtagctgct gtagcattgc ctttagcctt ggcttttggg gtatcaagcg gagctgatgc
    47641 ggccgcaggt ttgattacgg ctatcattgc cggtatcgtt attggcggtt tatcaggcgg
    47701 tttttatcaa atatcaggtc cgacaggtgc gatggcagct atcttgatgt ctattgcggc
    47761 aacaaaggga atgcaaggtg tattgcttgc tactttttta gcgggtctat ttttacttgc
    47821 agcaggactt ttccgattag gaacactgac ttcttttatc ccagcacccg taattacggg
    47881 gtttacttca ggtattgcta tcattattgc attaggtcag atcgataatt tatttggtgt
    47941 tcactcggaa ggtacaaacg ttattgaaaa actaagtagt tatcaaacga taggatttcc
    48001 gataaacaca gcctctttga tcatgggagg gctagtcatt ttagggatgt ttatctatcc
    48061 aaaaaaatgg gcgaaacgaa tgcctagttc gctgctggct atcattttgg caacagcagt
    48121 tatgctattg ttccatttac cagtagcaac tgtgggtaag attccacaaa cattgatcag
    48181 tagtaatcgt ttgaatatgg gagattttag cttttctgcc ttgcaacaag tggcagttcc
    48241 agctattagc attgctttat taggaatgat tgaaagcttg ctatgtggtg cttcggctgg
    48301 ccgaatggca aataagccct tagatagcaa tcaagaatta atggcgcaag gaattggaaa
    48361 tctgttgctt cctttctttg gcgggattcc tgctactgcg gccatcgccc gtacaagcgt
    48421 ggccatcaaa tctggtgcac aaactagatt agctggtatg atacatgcag ttgtcttact
    48481 gctctccatg cttgtttttg cgccagtgat gtcacagatt ccaatgccag cacttgcagg
    48541 tgttttgatt gtgacggctt ggcgtatgaa tgaatgggaa acgatcaagg agctatttac
    48601 taataaatat tggtcagcag ttctattgtt tatccttacg atgatttgta cagttatctt
    48661 tgatttaagt attgctatcg tgatcggggt gatcggcggc tgtgtatttt ttgttgtcaa
    48721 aagcgctgct atcacgattt cattagaaac gatcgattgg caaagaatgg ggctgccaga
    48781 aacggaaaag ctgaataact ggacagtagt gtatattagt ggtccactgt tttttatgtc
    48841 ttcagaaaaa ctcaaaaata aattggaaga actaaatcat cacgatggtg tcattttctc
    48901 catgcgaggc gtaccaagta ttgatttgac ggcacgtgca gtttttgatg aatttcaaga
    48961 aaaagcagag caaagaggac aaacgattat ctatacttcc ttgcagccag aagtagaaaa
    49021 acaactttct cacttgtggg aacatacatt cacgcatcaa catcaaacag ttgctcatgc
    49081 gttgacagct ttacatgcga aatatactgc aattagccat taaaacaatg aaaaagaaca
    49141 gacaagactg taaactgaag attttatggt cttgtctgtt ctttttaata ttgctgtaaa
    49201 agtgaagcta gtacttgcca gtcttgatgg ataacaggta caagggagcg attgtagaaa
    49261 atagctgctg gatgaaaaag tggaagaatt cgatagtttt tttctgacca ttcgtaggca
    49321 tccttttgtt ctgttaattg taagacaggc cctgtataga gttgaccatg atttttggta
    49381 accgtatatt ctttgccaag taaacgttga agaccaatgt ttccaagtgt cgcaattaat
    49441 tttggctgga ccttcatcag ttcgtaatcc aatattggtg catgcgcaaa tacttcggaa
    49501 cgagtaggtg tccgatttgg ataaacagtt tctgactgtt gtgtccgttt attgatccga
    49561 tgagtcacgc gatacgggcg gctccttaca gcactggtga tatacacctc ttctcgtgtt
    49621 aagccagttg aagaaagtgc ctgcatcaat tcttttccag cttgaccgct aaaaggaaca
    49681 tgcgtatcaa tctctgtttt ccctggggct tctcccacga gcatcagttt aggatgaaga
    49741 ggtccttgcc cagcgataaa tccttctaca ggacggccgt tcattcttaa agaagcttct
    49801 tgtatcagtt cttttgggta ttccatttat gctcctcctt tttcttttat tataagaata
    49861 aaagaaacac aatgcgacta ttttatttgg tagaactgtg aggatagaaa agcagaagta
    49921 ttgcttgaat ttttgtttta ctttttgatt ttaaatttag ttgactaacg gttgctgttc
    49981 tggtaagcta gtactgttgt aattgtggac tccacagcta caaccgctca gaacaagtaa
    50041 taagcacagc atatgctgtc acttcggatg gcgagtctaa gtatatcaga aggaggtgct
    50101 ttatagcatg tacgcaatta ttaaaactgg tggtaaacaa gtaaaagttg aagtgggaca
    50161 agcaatctat gttgaaaaac ttgacgttga agcaggagaa aaagttgttt ttgacgaagt
    50221 tatcttagta ggcggagaat ctacaaaagt aggcgctcca actgttgcag gtgcaactgt
    50281 tgaaggtact gttgaaaaac acggcaaaca aaagaaagtc gttactttca aatacaaacc
    50341 taaaaaacat tcacaccgta aacaaggtca tcgtcaacca tatacaaaag tggttatcga
    50401 cgcgatcaac gcttaatagc gtttgagaaa gaaggcctat atatgatcaa aggaacattt
    50461 aagcgaaatg acgcaggtca gatcgtttca ttcactttga ccgggcatgc tgatgctggt
    50521 ccttatggaa gtgatatcgt ttgtgcgggt gtttctgcgt tagcgatcag cactgtcaac
    50581 gggattgcct cattagccgg ttttgagccg attgttgaaa tgaatgaaga agaaggcggt
    50641 tatctttata ccgaagtcac ttcaggaatg acacaagaac aaaacaatat tgctgagatt
    50701 ctattagaaa atcttttatt aggattacaa tcgatagaag ctgaaaactc agaatatatc
    50761 caaattaaaa caattaatga taaataggag gtgcagacca tgttgttatc tatgaatcta
    50821 caattatttg cccacaaaaa aggtggcggt tctacatcta acggccgtga ctcagaatca
    50881 aaacgtctag gtgctaaacg tgctgatgga caaacagtta caggtggatc aattctttac
    50941 cgtcaacgcg gtacaaaaat ctatccaggt gtaaacgtgg gtatcggtgg agacgacact
    51001 ttatttgcaa aagttgatgg cgtagtacgt ttcgaacgta aaggccgtaa caaaaaacaa
    51061 gtgtctgttt atccagtagc tcaagaagct taattgaatc ttatgattaa agaggttgtg
    51121 acaaga
//
LOCUS       DACBYO010000009        50520 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.009, whole genome shotgun sequence.
ACCESSION   DACBYO010000009 DACBYO010000000
VERSION     DACBYO010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.009"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(154..300)
                     /locus_tag="IVD26_000516"
     CDS             complement(154..300)
                     /locus_tag="IVD26_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HAP6078519.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(404..715)
                     /locus_tag="IVD26_000517"
     CDS             complement(404..715)
                     /locus_tag="IVD26_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP6078520.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(717..914)
                     /locus_tag="IVD26_000518"
     CDS             complement(717..914)
                     /locus_tag="IVD26_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAP6078521.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1308..3035)
                     /locus_tag="IVD26_000519"
     CDS             complement(1308..3035)
                     /locus_tag="IVD26_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP6078522.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(3028..4221)
                     /locus_tag="IVD26_000520"
     CDS             complement(3028..4221)
                     /locus_tag="IVD26_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP6078523.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4408..5052)
                     /locus_tag="IVD26_000521"
     CDS             complement(4408..5052)
                     /locus_tag="IVD26_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6078524.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(5146..5280)
                     /locus_tag="IVD26_000522"
     CDS             complement(5146..5280)
                     /locus_tag="IVD26_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAP6078525.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5282..7414)
                     /gene="feoB"
                     /locus_tag="IVD26_000523"
     CDS             complement(5282..7414)
                     /gene="feoB"
                     /locus_tag="IVD26_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAP6078526.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7411..7884)
                     /locus_tag="IVD26_000524"
     CDS             complement(7411..7884)
                     /locus_tag="IVD26_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAP6078527.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8285..8509
                     /gene="nrdH"
                     /locus_tag="IVD26_000525"
     CDS             8285..8509
                     /gene="nrdH"
                     /locus_tag="IVD26_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAP6078528.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8668..10827
                     /gene="nrdE"
                     /locus_tag="IVD26_000526"
     CDS             8668..10827
                     /gene="nrdE"
                     /locus_tag="IVD26_000526"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAP6078529.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10877..11842
                     /gene="nrdF"
                     /locus_tag="IVD26_000527"
     CDS             10877..11842
                     /gene="nrdF"
                     /locus_tag="IVD26_000527"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAP6078530.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11931..13070)
                     /locus_tag="IVD26_000528"
     CDS             complement(11931..13070)
                     /locus_tag="IVD26_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP6078531.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13379..14092)
                     /locus_tag="IVD26_000529"
     CDS             complement(13379..14092)
                     /locus_tag="IVD26_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAP6078532.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14346..15047)
                     /gene="nagB"
                     /locus_tag="IVD26_000530"
     CDS             complement(14346..15047)
                     /gene="nagB"
                     /locus_tag="IVD26_000530"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAP6078533.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15281..16813
                     /locus_tag="IVD26_000531"
     CDS             15281..16813
                     /locus_tag="IVD26_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP6078534.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(17004..18206)
                     /locus_tag="IVD26_000532"
     CDS             complement(17004..18206)
                     /locus_tag="IVD26_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6078535.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(18288..18977)
                     /locus_tag="IVD26_000533"
     CDS             complement(18288..18977)
                     /locus_tag="IVD26_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP6078536.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(19083..19451)
                     /gene="rplL"
                     /locus_tag="IVD26_000534"
     CDS             complement(19083..19451)
                     /gene="rplL"
                     /locus_tag="IVD26_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAP6078537.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(19504..20007)
                     /locus_tag="IVD26_000535"
     CDS             complement(19504..20007)
                     /locus_tag="IVD26_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAP6078538.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(20417..21106)
                     /gene="rplA"
                     /locus_tag="IVD26_000536"
     CDS             complement(20417..21106)
                     /gene="rplA"
                     /locus_tag="IVD26_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAP6078539.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(21210..21632)
                     /gene="rplK"
                     /locus_tag="IVD26_000537"
     CDS             complement(21210..21632)
                     /gene="rplK"
                     /locus_tag="IVD26_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAP6078540.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            21975..22643
                     /gene="sdaAB"
                     /locus_tag="IVD26_000538"
     CDS             21975..22643
                     /gene="sdaAB"
                     /locus_tag="IVD26_000538"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAP6078541.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            22656..23528
                     /gene="sdaAA"
                     /locus_tag="IVD26_000539"
     CDS             22656..23528
                     /gene="sdaAA"
                     /locus_tag="IVD26_000539"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAP6078542.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(23619..24638)
                     /locus_tag="IVD26_000540"
     CDS             complement(23619..24638)
                     /locus_tag="IVD26_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAP6078543.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(24811..25698)
                     /locus_tag="IVD26_000541"
     CDS             complement(24811..25698)
                     /locus_tag="IVD26_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP6078544.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(25775..26320)
                     /gene="nusG"
                     /locus_tag="IVD26_000542"
     CDS             complement(25775..26320)
                     /gene="nusG"
                     /locus_tag="IVD26_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAP6078545.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(26421..26591)
                     /gene="secE"
                     /locus_tag="IVD26_000543"
     CDS             complement(26421..26591)
                     /gene="secE"
                     /locus_tag="IVD26_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAP6078546.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(26615..26767)
                     /gene="rpmG"
                     /locus_tag="IVD26_000544"
     CDS             complement(26615..26767)
                     /gene="rpmG"
                     /locus_tag="IVD26_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP6078547.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            26929..27573
                     /locus_tag="IVD26_000545"
     CDS             26929..27573
                     /locus_tag="IVD26_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP6078548.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(27629..28132)
                     /locus_tag="IVD26_000546"
     CDS             complement(27629..28132)
                     /locus_tag="IVD26_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAP6078549.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(28145..28191)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            28729..29694
                     /locus_tag="IVD26_000547"
     CDS             28729..29694
                     /locus_tag="IVD26_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAP6078550.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(29793..30965)
                     /locus_tag="IVD26_000548"
     CDS             complement(29793..30965)
                     /locus_tag="IVD26_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6078551.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(30952..32097)
                     /locus_tag="IVD26_000549"
     CDS             complement(30952..32097)
                     /locus_tag="IVD26_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6078552.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(32111..33035)
                     /locus_tag="IVD26_000550"
                     /pseudo
     CDS             complement(32111..33035)
                     /locus_tag="IVD26_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            33152..34231
                     /locus_tag="IVD26_000551"
     CDS             33152..34231
                     /locus_tag="IVD26_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP6078553.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            34263..34856
                     /locus_tag="IVD26_000552"
     CDS             34263..34856
                     /locus_tag="IVD26_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6078554.1"
                     /translation="MTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIR
                     MPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQNLQAIIPSV
                     KSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIAD
                     ALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(34966..35193)
                     /locus_tag="IVD26_000553"
     CDS             complement(34966..35193)
                     /locus_tag="IVD26_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP6078555.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(35296..37884)
                     /locus_tag="IVD26_000554"
     CDS             complement(35296..37884)
                     /locus_tag="IVD26_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAP6078556.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(37904..38563)
                     /locus_tag="IVD26_000555"
     CDS             complement(37904..38563)
                     /locus_tag="IVD26_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP6078557.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(38612..39115)
                     /gene="trmL"
                     /locus_tag="IVD26_000556"
     CDS             complement(38612..39115)
                     /gene="trmL"
                     /locus_tag="IVD26_000556"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAP6078558.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(39336..40202)
                     /locus_tag="IVD26_000557"
     CDS             complement(39336..40202)
                     /locus_tag="IVD26_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP6078559.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            40311..40952
                     /locus_tag="IVD26_000558"
     CDS             40311..40952
                     /locus_tag="IVD26_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAP6078560.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(41014..42375)
                     /gene="mgtE"
                     /locus_tag="IVD26_000559"
     CDS             complement(41014..42375)
                     /gene="mgtE"
                     /locus_tag="IVD26_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAP6078561.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(42393..43292)
                     /locus_tag="IVD26_000560"
     CDS             complement(42393..43292)
                     /locus_tag="IVD26_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP6078562.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(43294..44091)
                     /locus_tag="IVD26_000561"
     CDS             complement(43294..44091)
                     /locus_tag="IVD26_000561"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAP6078563.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(44069..44773)
                     /locus_tag="IVD26_000562"
     CDS             complement(44069..44773)
                     /locus_tag="IVD26_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAP6078564.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            44904..45479
                     /locus_tag="IVD26_000563"
     CDS             44904..45479
                     /locus_tag="IVD26_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAP6078565.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            45597..46274
                     /locus_tag="IVD26_000564"
     CDS             45597..46274
                     /locus_tag="IVD26_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAP6078566.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(46353..48161)
                     /gene="pepF"
                     /locus_tag="IVD26_000565"
     CDS             complement(46353..48161)
                     /gene="pepF"
                     /locus_tag="IVD26_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAP6078567.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(48337..49335)
                     /locus_tag="IVD26_000566"
     CDS             complement(48337..49335)
                     /locus_tag="IVD26_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAP6078568.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(49561..50214)
                     /locus_tag="IVD26_000567"
     CDS             complement(49561..50214)
                     /locus_tag="IVD26_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAP6078569.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        15148 a        10573 c         8826 g        15973 t
ORIGIN      
        1 aaaaagatat tttcttttgt taagatcagt attagtcata taaaataaga gaaaaaagaa
       61 aaagtttccc acgaacattc ttaatagata agcttttgta tcgatagtaa tcaagagatc
      121 ccctcctgat tttaggatat cataaaaaaa attttagtta cactttttaa ataatgaaaa
      181 aacacattcc actaaatttg atgccggttt tccttgaggt tttgttccag cacctccttt
      241 aattttttta agctcttgat ctgaacattg tttagcattt agtctatttt tttcttccat
      301 tacgattccc cctacaaact ataaatactt ttatgtcact gattcaatat acctattttt
      361 ctaatcaaaa aattttgaga catatttaat attataagta tcattaaaat tgagatttat
      421 ctccataatc tgctcgatat aaaccattta ttccagcagt tcttccaatt tcactcaaat
      481 ttcttattaa ttcctcttga tattcagtga atcttatttt attagtataa gcagtaaaat
      541 atagataatt caccaatcta tttattaaag gaccgggatc taattcatat ttttgttttt
      601 ctaattttaa atataccttt tgtaaaacct caagaatatc agaatattta ggatctttac
      661 ttatagatat atcattatat aattcatgaa caatttgctt agcatttttt ttcattttag
      721 cacttccctg gaattgctcc acctaaaaaa ccacctatag acattcctgc aatacaagta
      781 gttgccttgg cccaatcgac cgtacattta tttttagtgc aatacactcc atttccataa
      841 tattttccac tatgagtggt acccccatag ataagttgtg tctctttaat agacaaaatt
      901 tttaaatgtt tcataatcta atcaccccta aattaatgtt tttagactat tattctaaca
      961 ttcattaaat ttcaaaaaac aattccttct tgaaacgtag caaaataatt cctgaataag
     1021 aatttaatca cttttaagta tataaactat gtatattctt taatattttt tgagaatgca
     1081 cttcgtacat aataaacttt aatcacatta gtctttcata cctacgatcg atctctttga
     1141 ctcgcaccca taaattcata atagtttgtc ggcgtctttg gacgtttcga agatgagcta
     1201 cgcattctct ttttttatag acaaaaaaga tagagacgaa catggagctt ccaaatttgg
     1261 atatttgatc caattttgga agctccattt atttcgtgtc tgtcttttta ttttttccag
     1321 ctttcgacta attcttggtt ctctttgatc cagtcttttg ctgcttgctg tggatctttt
     1381 ccattgttga tttccaacat aactttttcc atatcttttt ctgaccaatg gaaattgtct
     1441 aatactttgt aagcttctgg ctggtcttct ttcaatcctt ttcgaaccat cgtatggatc
     1501 tgctcttcgc ttcccattcc gttttcagga tcttctaagt atttcagatc atatttggca
     1561 aacatccaat gaggtgtcca tcctgtaact acaattggtt cgtgtttttt gatcgcttga
     1621 cctagtgcaa cggtcattgc tcctgaagaa gatgtctcta ctttccagtc tttcaagttg
     1681 tcatattttt ggatcgtgtt ttcagcagcc gtaactacac cagctcctgg ctcgattcct
     1741 atgattttct tacctgcctg atcggttaac tcatcgatcg aatttacatc catgtaggct
     1801 ggcactgcta aaccaacttt tgctcctgtc aaattggcac ctaggtcttc gacttgatct
     1861 ttatattgtg catattgtga accatgagtt ttaggtagcc aagctgaaac catggcatct
     1921 gactcgccat ttgaaacaga tttccacatg attgaattat ctaatggcgt catcgttaca
     1981 tcatagccca tttgtttcaa tacttcaccg actacatttg ttgaagcaac ttctgtatcc
     2041 cattcaacat aagataagtt gatacgtttt gtttctttgg cagatgaaaa actccctata
     2101 ccaatcgcac ctaagatcac tactactaca gcaccaatga tcagtccttg acgtttttta
     2161 cttttctgtg ttgttgctcc tgcagctttt ttattgtttg gctggttcaa atgctgtgta
     2221 aaacggtcaa tgatgattgc taagataact aatgcaaccc cgttgacaaa tccattcccg
     2281 acttgtgctc tttgcaatgc tgataatacg ccgcgtccta agccgggtgc accgatcata
     2341 gaggcaataa cgaccattga aagtgacagc attgttgttt gattgatccc tgccatgatc
     2401 gtacttttag ctaaaggcaa ttctagtttg aatagttttt gacgacttgt gctcccgaat
     2461 gaatcagaag cttctactaa ttctttagga acttgtcgaa tccctaaatt cgtaaaacga
     2521 acggttggtg gcagagcaaa gatgactgag gcaaataccc ctggaaccat cccgataccg
     2581 aaaaatgcaa ctgctggaat caaataaacg aatcctggca ttgtctgcat aaagtcaagg
     2641 atcggtttga taatactttg ggctttactg ctttttgcca tcaagatccc taatggtacc
     2701 ccaatgatga tcgagatcac actagataaa agaacaagtg tgacagtatt catcaaatca
     2761 ttccatagac cttggttata aataaaccat agaccgatta atgtgaacaa cgtaagtcct
     2821 ggacgtttct tagaaataaa gaaagctgct accgtcaata acaagataaa caaaggagct
     2881 ggaatcacta acagtaaatt tgtaatcccc gacatcactg cctgtccaat cgtttgtaaa
     2941 aatgaaaata ggccagaaaa agttgtcgta aaccattctg tgatattttc tacccagttt
     3001 gccactggta attgatagtt caatagatta ttcatgttca ctcacctcgc ttgtttctgc
     3061 taatgcttca atcacactac ctcggatgac gacacctttt aattttccat cctctacaac
     3121 tgcaagtgga gtcggtgagt cataaataat attgaaaata tcacttacca ccatgtcttt
     3181 cccaatcacc gtcacatttt catctaggaa gtcgatcaat ggacgttttt gcttcctagc
     3241 ttctaacgct tgatctgcag tgatgatccc tttcaggtgt ctctttctgt caacagccat
     3301 cagcatgctg acttcttcat tacgcatcct tgtcaatgca acgtttggtc catcagattc
     3361 gatattcgtc gtcaatgcag gtaccatgat gttttgagcc gtaagcactt tggaacgatc
     3421 gacttcttcc acaaattcac gtacataatc atttgctgga ttggtcaata tttcttcacc
     3481 tgttccgatc tgcatgattt cgccgtcttt catcaaggcg attctgtccc caatccgtaa
     3541 agcttcattc aaatcatggg taatgaaaat aatcgttttt tgaacattgg cttgcaggtc
     3601 cagtaattcg tcttgcattt ctcgccggat cagcggatca agagccgaga acgcttcgtc
     3661 catcagcaag atctcaggat catttgctaa agctctggct aggccaaccc gttgttgcat
     3721 cccaccagat aactgactag gatattggtc tttaaatgaa agcaaactag aattttctaa
     3781 tgctttttct gctttttctt gtcgttcttc tttaggtaca ccacggactt ctaacccgta
     3841 ttctgtattt tccaagatcg ttcgatgtgg aaacagaccg aagttttgga aaaccatatt
     3901 gattttatga cgacggactt ctcgcaattc ttctttgctt aacttcgata catcttctcc
     3961 atcaatatag atactgcccg aagttggctc aatcagacga ttcaatagac ggatcaatgt
     4021 ggatttccca ctcccggaaa gccccatgat cacgaagatt tctccttctt ttacgtcaaa
     4081 attcacgtca tacacaccaa ccgttgcacc ggttttcttt aaaatctccg ttttcggctg
     4141 gtgatcattc atcatatcta aagcggcttg tgtcttttta ccaaatatct ttgttaaatg
     4201 ttttacttct acttttacca aacaaattct ccttttttat gtaaattcat ttttctttct
     4261 gaaaaaagtg accacactat gttaacatca tgtagtcact ttgtcaaaaa tgaaagaaat
     4321 ttgcttgtcc aaactgaaaa aaacttggct aaatctttgt aaataaaagg tttagccaag
     4381 ttaatatttt tttaatattt cacacaatca ttctgcaagc tgatgctccg ggtaaaaaaa
     4441 gtttgtcata cgctgtagtg tatattcatt tccaataaaa tgaacgatgt cccctgccgt
     4501 aaatttagca taggggccag gtgaaacaag cagttcttca ttatgagaaa ttgcgataac
     4561 tgtggcgcca gtcgcctgcc agatattcaa ctcgctaatt gaacggtcca gatgcattgc
     4621 tttttctgat aaagataatt caaacggaag taaaggattc atcttatgta ttcgcttcgt
     4681 ttgattgacc agctgatcca ataattgaga aaaatgattc agctcatctt gttgcttctc
     4741 cacacttgcc atgatttctg cttttgtatc ttggatggat tgtacatctt gatattgcaa
     4801 taggaaatct tttgcttttt ccttcgaagc aacaaatgcc ccacttccat gccgtacttc
     4861 catgattcca agatctacca gcacattgat agccttgcgg gtagtctcag gagaagcatt
     4921 gtacgtactg gcaagtgttg agcgggcatg gatcttctca cccactttat atcggttttc
     4981 aacgatacgt tcggctaaat caacagcaat ctgctggtag cgcgggcgga cgattttttt
     5041 ctttccagac attttctttc ctctttcttt ttttactttc cctcatctta ctatgctcta
     5101 gcaaaataag caaaaaaggg gagaatagcc tcttgcaacg actgatcatc gcttgatctg
     5161 ttcctttttt actgggcaag ctgtttgaca gtcatcacaa ttcttaccgg attttaaacg
     5221 agtatagaca attgcgcctg cacttccaaa gattaacaca cttaataaga atgtcgccat
     5281 cctattcctc tccttctaat gacaatatag tataaaactg gttcttggat tttggctgac
     5341 ggaacaaaac ataaacgagt cctatcatca gtaaaatagc aagatacgtc cctaacgcta
     5401 cctgtccacc ctccaataag tgtcccaact gataaatcac aaaactaact aaataagcta
     5461 aaccgcattg atagcctatg gcgatccaag tccatttctt ggcattcatt tcccgatgga
     5521 tagccccaat tgccgcaaaa caaggcgcac aaagtaaatt gaaggctaac aatgaataag
     5581 ctgctgcggg agtatatgtg tgttgtagca cttgccagat ttctctgcca ttttcggata
     5641 cttccgcatg accaaacaaa ataccaaatg tgccaataat attttcttta gcgaccaatc
     5701 ctgtaatcgc tgcgactgtt ccttgccagt ttccccaacc aagcggctga aaaacaactg
     5761 ccaggattcg cccgaaaaag gctaagatac tttggtcttc agaaacaggt tgagcataaa
     5821 aattataaga agagctgaac cagatcacga tactagaaac aaagataatc gttcctgctt
     5881 ttttaacaaa agacttgctg cggtcatagg tttgtcttag gaccgctgac cattgaggaa
     5941 aatgatatgc gggcaattcc atgataaaag gagctgtatc tccagcaaac aaacgtgttt
     6001 ttttcaagct gattccagag aaaataattg cagtcatacc aagaaaatag gcagaaggag
     6061 ctacccaaga ttgatgagga aaaaaggccc ctgctactaa ggcaataatc ggcaactttg
     6121 cagaacaagg catgaaggtt gtgaccatga tcgtcaaacg acgatcttgc tcgttttcaa
     6181 tcgtgcgact ggccatgacg cctggcactc cacatcctgt agcaatcagc ataggaatga
     6241 aggattttcc tgaaagaccg aatttcctga aaagtcgatc catgacaaaa gcgatcctcg
     6301 ccatatatcc gcagtcttcc agaaagctca agcataaaaa caatataatc aattgcggta
     6361 gaaatcctaa cactgctccc acgcctgcga tgatgccgtt caagatcagc tcctgcatcc
     6421 atcccgctac ttgccattca gctaacaatc tgccaacatg ttctggtaac catgtaccaa
     6481 acaatgtgtc attgatccaa tctgtcccca ttgttcctac tgtttgaata gccagataat
     6541 agatcagcca catcacaaat gcgaagatcg gcaaggctaa ccaacgattc gttgcaatct
     6601 gatcgatttt gtcactcatc gataattgga aagaatcatt tgacacaaca cagagtgtac
     6661 atagttgggt aataaattca taacgttcat tgaccagaat cgtctcacta tcgtcgtcca
     6721 atagtttctc tgttaactgg atcagttgct cgatctcttt ttgctgagaa actgctatct
     6781 cgtaatcctc tcttaccttc tgatctcgtt caaaatattt cattgcatac cagcgtttct
     6841 tgccgctttg ttctcctagt acatcttcaa tttcatgtaa agctgcttct aaacgtggat
     6901 catatgtaca gggaacagga atagaaggcc gcttttttgc agactcctga atcttttcga
     6961 ttagtttttc gattccttgc tttttcaata cgctgattgg taaaactggt acaccaagac
     7021 cataggaaag cttttctaga ttgatttttt ttccttcttt tttgatgaca tccatcatat
     7081 tcagaccaat gatcatagga atgtctaaat ccaataactg cgtagttaaa taaagatttc
     7141 gttctaaatt ggtagcatca ataatgttga tgatcagttc aggctgttcc tgaaccaaat
     7201 aatctcttgc aatcacttct tctggtgtat aaggagacaa agaatagatg ccgggtaggt
     7261 cctgaatatg aatgttcgga ttttttttca acgatccttc ttttttttct actgttacgc
     7321 ccggccaatt ccctacatat tgattcgaac cagtcaagag attgaacaag ctagttttcc
     7381 cgctgtttgg atttccgact aacgcgatat tcattctttt tcctcccttt gtatcaagat
     7441 tagttcggcc tctgactttc gtaacgtcag ttcataccct cgcactgtca gttcgattgg
     7501 atctcccaga ggggctagtt ttcggataac tatttttaca tttcgcgtca atcccatatc
     7561 cattaaccgt cgcttcactg cgccttgtcc gtggattgct acgacgatcc cagtctctcc
     7621 tgcttttaat tgatcaagag aagtccagct ttcagaggaa gcagtctttt tattgacaaa
     7681 gatttgacct agtatttccc gacttactgc cactcgatga ctttttacca gtaaaatggc
     7741 attgttgcct gataaattga cgacgacgat tttacttccg gcaacgatcc cgatattttg
     7801 caaatggcgt tttgtttttt cttctgtttc gattcgttcg acttgataaa cgaaattctg
     7861 ctttgcctgc gctaaggtct gcatattgat tcctctcttg tgaaataaat catgtattaa
     7921 aatcattcat tatatgttct aattttctta cgtgttacgc aaataaatga gaatcattct
     7981 cacatagaat actctcggta attgagaatg tcaattatac ttgtgatatt atgagcgaat
     8041 ctttagtatt gatagataaa aatgagaaaa aaatatttct tcatagtttt ccacaatttt
     8101 ttctctatta aatttgctat tttcccacac gatacttgtt ttcagctctt ttttcaaaaa
     8161 cacaaaactt agtattccac agtttccaca acacaatatg tagtgtttgt tgtttgactt
     8221 ttttactaag agttttatac tatctattat agataataag aatgtgttag aggaggcact
     8281 caccatgaac gtaaaaatct tttctaaaaa taattgtatg caatgtaaga tggtcaaacg
     8341 gtttttaaca gaaaatcaaa ttgcttttga agaagtcaat atcgatgaac agcctgaagc
     8401 agtagactgg ttgaaagcac aaggattcca aagtgttcct gtcattactt ctgatgcaga
     8461 aacagttatc ggattccgtc ctgatcagtt gcgtaaactt gccagctaac atgactaaaa
     8521 gaatcaaaac gtgatacatg gatttgaagg gcttgagaca gcaccagttt ttgtcgcaaa
     8581 cttccaaatc cttttttaaa gcttaaaaac aatgcaatga tttgcaatca agcatcatca
     8641 aatacgaaat gaaggttggg cgtacgtatg agtcttaaaa atttacaaga tgtcagttat
     8701 ttcaagctga ataatgaaat caatcggcca gtcaatggtc aaatcccttt gaataaggat
     8761 aaagaagctt tagttgcctt ttttgaggaa aatgtcaaac caaatacgat gacttttcta
     8821 tctattatgg aaaaaatcaa ttacttgatc gatcaagaat atatagaagc agaattcatt
     8881 caattgtatt caccatcatt tattgaaaag ctatatcaat ttttggacga gcaacatttt
     8941 tctttcaaat cttttatggc tgcttacaaa ttttattctc aatatgcgtt gaaaaccaac
     9001 gacggttccg cttatctgga aacttatgaa gatcgagtag ccttcaatgc gctttacttt
     9061 gcgaacgggg atgaagaatt agcacttgct cttgcagacg aaatgatcca tcaacgatat
     9121 cagccagcta caccttcttt cttgaatgct ggacgtaaac gtcggggcga attggtgtct
     9181 tgtttcttga ctcaagtcac tgacgatatg aactctatcg ggcgctcaat caactctgct
     9241 ttgcaattgt cccgtattgg tggcggcgta gggattactt tatcaaatct tcgtgaagcc
     9301 ggcgctccta tcaaaggata tgagggtgct gcaagtggtg tcgttccagt catgaaatta
     9361 ttcgaagata gtttcagcta ttctaatcaa ttaggtcagc gtcaaggagc tggcgtggtt
     9421 tatttgaacg ttttccatcc agacattatt gctttccttt cagcaaaaaa agaaaatgca
     9481 gatgaaaaga ttcgcgtaaa aactctttct cttggcgtga tcgtacctga taaattttat
     9541 gaattgacac gtaaaaacga agatatgtat ttatttagtc catatagtgt cgaaaaagaa
     9601 tatggtgtcc cattctctta tgtaaatatt acagctgagt atgatcatct agttgcaaat
     9661 ccaaacattc gcaaacaaaa aatcaaagcg cgtgatcttg aaaatgaaat ctcaaaatta
     9721 caacaagaat ctggctatcc ttacgtaatc aatattgata cagcgaaccg cgagaatcca
     9781 atcgatggca agatcatcat gagtaattta tgttcagaga ttttacaagt tcaaacgcct
     9841 tctgtgatta acggcaaaca ggaatatgaa gtattaggaa cggatatctc atgtaactta
     9901 ggctcgacaa atatcgtgaa tttgatgcaa agccctaact ttggtcaatc tgtgcgtacg
     9961 atgactcgtg cattgacatt tattacagat gcatctgata tcgatgtcgt accaccgatc
    10021 caaaacggaa ataagctgaa tcatacgatt ggattaggtg ccatgggctt acacacttat
    10081 cttgcaaaag aacaaatgga atatggctca gaggattcat tagactttac aaatatttac
    10141 ttcatgctgt tgaattattg gacacttgtt gaaagcaaca atatcgctcg tgaaagaaaa
    10201 caagttttcc ataattttga aaaatcagct tatgctgacg gcacttattt cgaaaaatac
    10261 gtaactggag aattccagcc aaaatcagaa aaagtcaaag cattgtttga aggcattttt
    10321 atcccaactg ctgaagattg gaatgctttg aaacaagcag taatgaaaga tggactgtat
    10381 catcaaaatc gcttggcagt agcaccaaat ggctcaattt catatatcaa cgatacgagt
    10441 gcaagtattc atcctatcac tcgcatgatc gaagaacgcc aagagaagaa aatcggtaaa
    10501 atttattacc cagcgcctta tctatccaat gagacgattc cgtattacac ttctgcttat
    10561 gatatggaca tgcgtaaagt aatcgatgtt tatgcaatgg cacaacaaca cgtcgatcaa
    10621 ggcatgagtt tgactttatt catgcgttct gaaatcccag aaggcattta tgaatggaag
    10681 acaacaacga agcaaacgac acgtgatttg aatattttaa gacattacgc tttccacaaa
    10741 ggaatcaaat ccatttatta cgtacgtacc tttactgatg atgcagaaga aatcggaagc
    10801 aatcaatgtg aaagctgcgt gatctaatat catagataga ttcgcttatt catattttaa
    10861 ttaaaggagc attctcatgt cagaaacata ttatgaagca ataaactgga atgaaattga
    10921 agatatcatt gataaatcca cttgggagaa gctgacagag caattttggc tagatacacg
    10981 tatcccactt tcaaatgacc tagatgattg gcgtacattg tctcaattgg aaaaagatac
    11041 agtaggacat gtatttggcg gtttgacact gctagatact gtccaatctg aaagtggcat
    11101 ggatcagttg cgtaaagatg tccgcactcc ccatgaagaa gccgttttga acaatattca
    11161 attcatggaa tccgttcatg ccaaaagtta ttcttctatt tttagtacac tgaatacgaa
    11221 aaaagaaatc gaagaaattt ttgactggac aaatacgaat ccttatctgc aaaaaaaagc
    11281 tgagcgtatc aatgaaatct acaaacacgg tacaccgcta gaaaagaaaa ttgccagcgt
    11341 ctttttagaa acattcttgt tctattcagg tttttatact cctctttatt atttaggaaa
    11401 caacaaattg gctaacgtag cagagatcat caaactaatc atccgagatg aatctgtaca
    11461 tggaacctac atcggttaca aattccaatt aggattcaac gagttacctg aagcagaaca
    11521 agaaacgtta aaagactgga tgtacaatct tctttatgag ctttacgaaa acgaagaacg
    11581 ttatacagaa gaattatacg atccaatcgg ctggacagaa gaagtcaaga cattcctacg
    11641 ctataatgcc aacaaagcat tgatgaacct agggatggat ccactctttc cagatactgc
    11701 caatgatgtc aacccaatcg taatgaacgg gatttcaaca ggcacaagca accatgactt
    11761 cttctcacaa gtcggaaacg gctatttgtt aggtcatgta gaagcgatga aagacgacga
    11821 ttatttgatt ggattggaat aaggatttat tttaattcaa aaatttttcg aaaaataaaa
    11881 agagtttagc gtacagatat tttaaatgta cactgaactc ttttttatgc ttattcactt
    11941 gtttcttcca gcacttttgg actgtctaac ttttccgaaa catgttccat tcttctcaat
    12001 aaatagattt tccggatatt taatattatc gtcttaatca ctgcatagac aggtatgcaa
    12061 atcagcatgc ctaatattcc tgcgacactt cctgctccaa tcaataccaa gatgatcgtc
    12121 aaaggatgga tattcattga tttcccaaat aacaacggct tgatcaaatt tccatctaat
    12181 tgttggatca ctaaaatcga caacgccata tacaaagctt gaaatggaga gataaacaaa
    12241 ccgacaatga ttgctggtac cgctccaata aaagggccga catacgggat aatattcgtg
    12301 attccgcaaa tgaccgcaag caacaagcta taaggctgat cgaatattct cattgccaaa
    12361 aagctcatta caccaataat caaagcatct aagatcgtac tgctgatata ggcagataat
    12421 gtttcgttta attcttttac cgtttggcgt aactctttac gaatcgcttt cggaaagaag
    12481 tgagacaacg catcaataaa tttgtgccca tccttgaaca taaatagcaa aataaatgga
    12541 acggtaaata acaaaataaa aaattgcatc ataaatgaaa tgatttttga gacacttgca
    12601 gataaactga ctaatatgat attgaacaaa ttactaagag ataaatttgc tgatgctaat
    12661 tgttcttcca aattgaaatt tttaaactct tcccgctgcg ccaattcatt taaccatttg
    12721 cttgtttcat ctgcatacat tggcaagctc tgggtcaatt gaattgtctg ttccattaac
    12781 tgaggcacta cattcatgac agttaaaaca actaaaatga ttacgaccaa aaacgtcaat
    12841 aaaaaaccga acactctcgg gatccgatgc ttttcgagaa aaacaacgat tggatcgaac
    12901 atataataga taaaaccagc aacaagcaat ggtaaaaaaa ctgccgaaag cattttcaat
    12961 attggactaa aaatattcgg catttgtaaa ataaagtaca cgccgatgat cgtgagtact
    13021 agctccactg tccagaaaaa taattttgat tgtttaaaac gtgattgcat acatctcctc
    13081 caaggtcctt tgatacttct attctatcat ttaacaaaga gttacgcgct gagattttca
    13141 tttgcttaaa aaaaacaaaa aaaataaaca tattttaatg agtagacgag tacttaaaca
    13201 aaaacacggt ttggagtagt gacaaaaatt atactgcagt ccctttttcc aaataaacgg
    13261 tgttcaaaag cttgcatctt cgtaataagc ccagccaaac gaaaaatata aggaactatt
    13321 tttatttggc tgggcttatt acttgatgta ggacatctat tttacaacct cagatcattt
    13381 attgcgcaat actgactaaa tgcaactttg tgatattttt gtgtacggac aactcctcga
    13441 tcacatcggc ataagtgagc ccttttggaa gatcaatcgt atagatattt ttgtacactc
    13501 ggtagtcatc aacgaatttt acgtcaaaat tcacatcttc gattacgata tttttctctt
    13561 caaaataatc ggtaagaaaa tctttggttt cttttctatg gataaattgg atttctaact
    13621 ttttagtcgt aggtacatgg atcacgcgtt tcactactgt gagtgcaata gcaatcccga
    13681 taaaactgat gatcgcaatg gaatagtaac ccatgccgat ggcgatccct aatccagcaa
    13741 ttgcccataa agaagcggca gtcgtaagtc ccgtcaccga ttgtttcgtg acgatgatcg
    13801 ttcccgcgcc taagaaaccg acaccactca ccacttgagc aatcagcctt gcttcatctg
    13861 aacgaatcgt tccagcaagc tgtggatact ctaaagcatc tcttaatgca ccactagcga
    13921 tctcaacttg gatcaatgca atgatacatg ctcccataca aactaaaata tgcgtacgca
    13981 tacctgctgg acgattttta tattgtcgtt caaaaccgat tgctccgcca aatagcatag
    14041 cgatccctaa acgtaaaata atctctggaa ttgtcaatac catatcattc atctaaacac
    14101 cctccagtcc aatatatcat gtctgaaagg agcagacaaa aaaagtgcaa tttttacctc
    14161 ttacgaaaaa aggactgtga caaaattttt gtcatagtcc tttttatgaa taaacggtgt
    14221 tcaatcagct gaccctcggt attactcaac aaacggcaaa atatggggag ctatttttcc
    14281 tttgtcttct ctaatactca ggtcaaaacg ctgatttcac aacctcttta gcctactatt
    14341 gaaaattaca acttacttgc tgcttcttca tcgatgatca caacaacatt gtcgtgattt
    14401 tgcaatacac ttgctggcaa atgattcgtt acaggtcctt caatcatccc tttgattgca
    14461 tcagctttgc tttcgccaaa tgccatcaag acgatttctt tacttttcat aattgaaccg
    14521 attcccattg aaacagcttt tgttggtaca tcttctgctt tatcgaagaa tcgtttgttt
    14581 gcattgattg ttgattctgt taagtcaact actgaagtcg ttccgtcaaa tgaagcacca
    14641 ggttcattga aaccgatatg tccattttgc ccgattccta agatttggat atcgattgga
    14701 tgtgcatcga tgatttgatc atactttttg catgctgctt ccagatcttc tgcttttcca
    14761 tctggtacaa acgtttcttt gaatggtttt ttatcaaata attggacatc catgaaatga
    14821 cggtagcttt gttcatctga accgcctagt ccaacgtact catctaagtt tacagaagtc
    14881 atttcactga aatccaaatc gcttgaagtc atttctttat ataaagtaac tggtgtgctt
    14941 cctgttgcca atcctaatac ttttgcacct ttgttcatac cttctttgat gatttcaaat
    15001 gctttttttc cgccttcttc agcgtttttt acacgaatga tttccatagt gattgctcct
    15061 ttatattttg gtatagccca attatagcat tctttttttc tttttacaat aattagtata
    15121 gaccaaattg catttttttc attttcttga caataaatag gaatccgtgt taggtttcat
    15181 aagatggttc aatcaaacaa tccatgttgc atgaaaacca agcaagtgat tcactgtgga
    15241 cgctttatgt ctgcagtttt tttatgaaaa aggagttatt atgagtatac tgacattaaa
    15301 caacattacc cagcaatttg gcgacaaaat cctctatgaa ggtgtcgatc tgcaattaaa
    15361 tgctggcgaa catcttgggc tgattggaca aaacggagcc ggtaaaagta cattgattaa
    15421 aatcatcact ggtgagatct taccagatga cggacagatc cattggcaaa aaaatattca
    15481 caaaggttac ctcgatcaat atgtggaagt cgatgaaaca ttaacaatcg aagaatttct
    15541 aaaaactgcg tacgcaaaag aatacgaaaa ggaagaaaaa attgcttttc tttaccaaac
    15601 atatagcgag accttcgatg attccttgct ggaaaaagct gggaaactcc aaacggaatt
    15661 agaccaagga gtgttttatc aaatcgacac cttagttgct gagatgagca gcgggttggg
    15721 gatcgatgtc ttaggtttag attcactgtt gaaaaatcta agtggtggac aacgttcaaa
    15781 ggtgatttta gcaaaactac ttttagaaaa cccagatgtt ctgatcttag atgaaccaac
    15841 caatcactta gatgatcagc atatccaatg gctgacgcag tttcttcagg attttgacgg
    15901 tgcgtatatc gtgatttccc atgaccaaga atttcttgat cagatcacca cccatatcgc
    15961 agacatcgag tttggaaaga ttactaagta tactggccat ctaaaacaag cattgaaaca
    16021 aaaggaacaa aatcgcgaaa gctatttgcg ccaatatcat gctcaacaaa aacaaatcga
    16081 aaagaccgaa gcttatattc gaaaatacaa agccggttcc cgatcaacga tggcaaaaag
    16141 ccgacaaaaa caattagata aaatcgaacg gctgacgcct ccagcttcag caagtaaagc
    16201 tgtctttgat tttccattct cgcctattgt cacgacatta gcagtggaaa caactgattt
    16261 agtcatcgga tatgatcgac cgctacttgc acccatcaat ttgaccatcc gctttggtga
    16321 aaatattgcc attcgaggct tcaacgggat tggaaaatct actttattaa aaacactgat
    16381 cggtgagatt gaaaaaataa gtggcgattt ccacttccca gataacacaa aaatcaatta
    16441 cttttcacaa gatctgtact gggaaaatcc attagaaaca ccactacaat atttaagcag
    16501 tcaatttcca aaagcgacta tcaaagaatt acgtcgccaa ctagctaaag cagggttagt
    16561 taatcaatta gcaagtgaac ctctcactac attaagtggt ggggaacaaa ctaaggtgaa
    16621 acttgcacag ttgacaatga accaaggtaa tttactgatt ctcgatgaac cgacgaacca
    16681 tatcgatcaa gaaacgaaag aaagcttaca agacgggata cagaaatttc caggaacagt
    16741 aatcatcgtc tctcatgaac aagaatttta tcaagatctt gtgcaacgag tcattgagat
    16801 tgaaccaaaa taaacgtttg attgaatagt tgaaaaaaag gagctgtgac aaaagttttg
    16861 tcacaactcc ttcttctgaa taaatggtgg ccaattagct gaccttcggt attagctcaa
    16921 aaaacggcaa aatatgagga gctattttta tttggctatt cttattactt gatgcagaac
    16981 agcttttcac aacctctttt cgtctatttt ttattttcga gatttctctt tcctttaaaa
    17041 acaactgttt gaaagaagaa cgcacatcct tgaaaaacaa gcccgctaac cgttacacct
    17101 aaccagccat actgctgcca cattgtcgtc cctagcaatg aaccagccgc acctccaata
    17161 aagtacataa acataaatac agtattattt cggttgcttg ctgcttcacc tagcccttgt
    17221 actcgtgttt gattggcgac ttgaccaaat tgattcccga cgtctaataa aataatagct
    17281 aaaagcaaaa tggccaaatg gcttccgcca accaataaag caataaagct tattgtttgc
    17341 ataacaagtc ccatatacac gatttttctt tcagaataag aatctgccag tcgtcccacg
    17401 ataggtgcag caactgctcc agacaaacca aaaatcgcta atatccctgc ttcgaatgtt
    17461 ccccaattgt aggcgggact gctgatataa aaaatcaacg tagaccaaaa gatcgaaaat
    17521 gttccaaaca tgaaaaatcc actgactgcc gcttctctta atagacgttg agaagcaact
    17581 aaatgcggca aacttttaag tgaatcaagg tatgaaacag ctgtactact ttgctggaca
    17641 gaacgcggca ttttccagta aagcagaagt gtaagaattc cgactgcaca taaagcaaat
    17701 aaatagatca tccgccaaga aaaaagactg gcaacaatac cagataccgt ccgagaaagc
    17761 aaaatcccca cgagtaaacc gctaagcaat gtacccatga ccttccctct tgcttttggt
    17821 cccgctagta ccgcaccgta aggaatgatg atttgcggca cgatcgaaag taatcctatt
    17881 aaaaaagaag cgcatgcaaa taacgtaaac gaaggcgcaa aaaaagcggc caacagagag
    17941 acggcagata acgctgccat tcgaatgatc aattttggac gatccaccac gtcccctaaa
    18001 ggaactaaaa acagtaaccc taacgcatag cctaattggg tcaacatcgt caatatcccg
    18061 actgcacttg tgctaacaga taaactagct gctacttttg ttccaatcgg ctggatgtaa
    18121 tacatattgg caacaacaac gccacaagtg attgataata gtaaaataag cgaagttgtt
    18181 aaaggttttt tttcattact cttcattgat ttcccccatt tcctatctta gtttacaact
    18241 tatggaaaag attggaaata gaaaaataca actattcgcc acacttatta tttgtgcttt
    18301 tgttttcctt gttttttctt gcgatcttta taaatgaaga caactaaccc tactagcaca
    18361 gtaacacttg caaccaacgt gactgcagtt ttgttatatc cgtgaaacag agcttctcca
    18421 ccacacgcat acaacacaga cgaagggatg actccaatca cgatcgacaa tatgatttgc
    18481 tgtagaggca atttcatcgc atctgcagca aaattgacca tagaagatgg aataaccggt
    18541 atcatatagc ctaacattac acctattttt ggatgtttca tttgtcggat tgcttgcacc
    18601 caatgattcg tttcggtttt cttatctaaa aattttaagc gatgcataag gaaaattgca
    18661 gtgatgttac caagagcatt acccaaaatg ttgatgatcg cacctgtcag tggtccaaag
    18721 ctcaaaccag caatgactcc aactactgaa gtaggaatac ctggaacagc acacatcacc
    18781 gctgtcaata cgatcaagag tatcgatgca aaagtcccat gcgaacgaat atgtgcgagt
    18841 agctctgcct tactcgctct cggatttaaa aataattgga tgtctgtctg atattctaaa
    18901 tacaaccgat agcccactac cagtatcaga atgattccca acgagatcaa tatcaatcgg
    18961 attattttct ttttcatatt tcctcctgaa aaaaatctat attcattaaa taatagttta
    19021 acataaaaac aaaaaagcac cgaaatccaa cataggatct cagtgctttt aaatagtaaa
    19081 aattatttaa cagttacaga tgcgccaact tcttcaagtt tagctttcaa ttcttcagct
    19141 tcttctttag atacgccttc tttaactggt gcaggagcgc catcaactac agctttagct
    19201 tctttcaagc ctaaaccagt tgcttcacga actgctttga taactttaac tttttggtct
    19261 ccagctgcag ttaattctac agtgaattct gtttgttctt cagcagcagc agcgccacca
    19321 gcagcagcta cagctacagg agcagcagca gatacgccaa attcttcttc aatagcttta
    19381 actaggtcgt taagttctag gatagttgct tcttttaact cagcaacgat gttttcaatg
    19441 ttcaatgcca ttataatttc ctccgtttaa ttgttctttt ttatttaatg ctttatgcgg
    19501 caattaagct gcatctccat cttctttgtc tgccactgct ttgacagcgt aagccacgtt
    19561 gcggactggc gcttgtagta cagatagcaa catagataga agtccttcgc gatttggcaa
    19621 ttttgccaat gctgtgattt cttccaatga agagacttta ccttcgatga taccgccttt
    19681 gatttctaat gcttttgctt ctttagcaaa ttcgtccatg attttcgctg gtgcgactac
    19741 atcttcgtta ctgaatgcaa cagctgtagg tccagtgaat acttcgtcca tgccttcaag
    19801 gccagctttt ttagctgcac gtgaaagaat agaatttttg ataactttca tttctacgtt
    19861 agcatcacga agttgtttac gtaaacgtgt tacttcatca actgttaatc cgcggtagtc
    19921 aacgactact actgatgcag ctgctgtaaa tttttcgctt acttcatcaa cgattgctgc
    19981 tttttttgcg ataattgctt cactcatttt tgagtttcac ctcctgaatt ttgatggaag
    20041 agttttttgc actgaaaagg caagtcactt ttatagttac tttgctcaac cagtattatt
    20101 catcacctat tcacttcgtt catagtgatt ctactcgctt tgctcgaaag gaaactcctt
    20161 tcgctttgct caaccagtat tgttcatcat ctcttcactt cgttcatagt gattcacaat
    20221 aaaaaactct atgccaccgc agacatagag ggactattga atatattcaa taaacgtcct
    20281 cggtaggaaa ttaaggcttg atgccaccta ctgtcttcgg tacaagttaa ttattaacct
    20341 caactagctt agcatgctaa actagttgag tcaagaatta tttttcagtt ggatcaatca
    20401 acattctaat atttaattag aaagaagctt ggtcaacatg gataccaggt ccaaatgttg
    20461 ttgtgatcgt tacatttttc atgtattgac ctttagctgc tgatggttta gcttttagca
    20521 atacatcatg gattgctgca aagttttcaa ctaatttttc atcgtcaaat gaaacttttc
    20581 cgattggtac atggatattt ccagctttgt ccacacggta agttacttta ccagctttca
    20641 cttcgtttac tgcttttgtt acgtccattg taactgtacc agttttaggg tttggcatta
    20701 agccttttgg tcctaatact cgtcctagac gacctacagt agccatcata tcaggtgttg
    20761 caacaactac atcaaagtca aaccatccgt tttggatttt ttgaaccatg tcgtcgtcac
    20821 ctacgaaatc tgcaccagct gcttcagctt cttttgcttt gtctccttta gcaaaaacta
    20881 aaacagtttg tgttttacca gttccgtttg gtaatacaac agcaccacgg atttgttggt
    20941 ctgctttttt agggtctacg ttcaaacggt atgcaacttc aactgttgca tcaaattttg
    21001 caatgtttgt ttcttttgct aaagctactg cttcggcaac aggataaact ttacttgaat
    21061 caactttttt taatgcatct tgcatttttt tgctcttttt agccattttg gttcctcctt
    21121 gattgtggtt ataacggttg tacctcccac gtgttctata tctttcaata tagagccaac
    21181 tgagaagctg ctgtcttagg gtgtatagat tattctacag tgatccccat gcttcgtgca
    21241 gttccttcaa ccatgcgcat tgctgcttca acgttagctg cgtttaggtc ttccattttt
    21301 aattcagcga tttctcttac ttgatcgcta gaaactttcg caactttatt tttgtttggt
    21361 tcgcctgaac ctttttcgat tttagctgct tttttcaata gaacagcagc tggcggtgtt
    21421 tttgtaacga atgtgaatga acggtcttcg tatacagaaa taacaaccgg aatgatcaaa
    21481 cctgcttgat cagctgtacg agcgttgaat tcttttgtga atcccatgat attgataccc
    21541 gcttgaccta gtgcaggacc tactggtgga gctggagttg ctttacctgc aggaatttgc
    21601 aatttaacga ttttttctac tttctttgcc acgagacata cctccttaag tccgtgatgt
    21661 ggttaattgg agatgcatat ttctcctccc acgttttatc tgatctgaaa aaatccagac
    21721 aaataatgtg caaaacaatg cacactggta cagtatagca aatttatttg ttttttcaag
    21781 atttttttct gctattttta cattttgctt gaataaacgc taaatttatt ctaaaaaaac
    21841 aacaattttt cgttctcatt tcttctttta tgttacactt gcgctagcat ggttcaacag
    21901 atgaaagcaa acaataacac ggttttttag acccttgtac aaagattcct acataacaaa
    21961 atgaggtgga gaaaatgaaa gatttaaggt atagaagtgt ctttgatatt attggacctg
    22021 tgatgattgg tccaagtagc tctcacactg ccggagctgc tagaatcggg aaaatcatac
    22081 gtagtatatt tggcgaacag cctgattctg tagatattta tctatatgaa tcatttgcaa
    22141 aaacctatcg ggggcacgga acagatattg cattagttgg cggcctgtta gggatggaac
    22201 ccgatgatga acgtttagct gattctttga aattggcata tgaagccggt atggaagtct
    22261 tgtttgttcc taagagtgaa aaagccgaac atccaaactc tgtaaagatg cttctaaaaa
    22321 aaggaacacg aaagctttca gtcactggca tttcgatcgg cggtggcaat atccagattt
    22381 ctgaattgaa tggattcaaa atttctttaa gcatgggtac tcctaccttg atcgttgtcc
    22441 accaagatgt tccaggtatg attgctaaag tgactagtat actttctgag accaatacga
    22501 atatcggcac tatgacagtg acacgggaat caaaaggtga aaatgccatt atgataattg
    22561 aagtagatga tcctcaagta gaagaaacgg taaaaagact caaacagctg ccaaatatcg
    22621 acagcgtaaa ttatttcgat taaggagcta aaaaaatgtt tttatcgatt gaagaattag
    22681 tagatcaagc aaaagcttat ccaagtgtag cagaattgat gattgcagtt gaaatggaaa
    22741 tgagtggccg ttcccgtagt cacatcatcg agatcatgga aaaaaacctc tcagtaatgg
    22801 aacaatcaat caacgaggga aaagaaggtg ttacctccgt cacaggaatt accggtggtg
    22861 atgcaaaaaa attagatgat tatttaaatg aggcagactt tttaagtgga gaaacaatct
    22921 taaaagctgt acgcaatgct gtagctgtta atgaagtcaa tgcaaaaatg gggttgattt
    22981 gtgctacacc gactgccgga agcgcgggtg ttgttcctgg tgtgctgatg gctgtccgag
    23041 atcggcttga tttgacacat gaacagcaat tggaattctt atttaccgct ggcgctttcg
    23101 ggttagtcat cgcaaacaac gcttctatca gtggtgcaga agggggatgt caagcagaag
    23161 ttggttctgc aagtgcaatg gcagcagcag ctttggtttg tgcaaaaaat gggactcctc
    23221 atcaagcagc acaagcagta gccattacat tgaaaaatat gatgggactg atttgcgatc
    23281 ccgttgcagg cttagttgaa gtcccgtgtg tcaaacgtaa tgctttaggc tcttctcaag
    23341 cttttatctc tgctgatatg gcattagcgg gtatcgaaag tgtcattccg ccggatgaag
    23401 tcgttgctgc aatgtaccaa gtcggacgtc aaatgccgtc gattttcaaa gaaacagcag
    23461 aaggtggctt agctgttacg ccaactgcta aacgacttgc ggaagagatt ttaaataaga
    23521 gggcgtgata aagctcctta atttcgagta ttaagagatt agttatcttc ataacaaaaa
    23581 acgaagagag gactaattgc ccttctcttc gttttttatt aatccatcaa tttcgtattt
    23641 tttacttcat cgatcgtttt tgttcctgca agttgcatcg tgatcgacaa ttctttgttc
    23701 aggtgttcaa aaacagatgt tactccttct gccccaccta gattcaaccc ataaatcact
    23761 ggtcggccaa tcgcaactaa gtcagcacca cttgccagag ctttgaagac atgctctcct
    23821 cgacggacac cagagtcgaa aatcactggt acacgtttgt tgactacttc ggcaattttt
    23881 ggcaatactt caaaggacgc aggacctcca tctagttgac gtccaccatg attggatacc
    23941 cagataccat ctgcccctgc agagatagcg attactgcat cttctggcga ttgtattcct
    24001 tttacgataa ctggaagatg ggtgatttct ttgattgttt tgatgtcatc tggtgtcaag
    24061 ccttgttttg cagctgcata aatttctgcg attccttttc cttcgccatt accacttgca
    24121 ctttgttcgc tatacgcagc taagttaggc attggtaatg gaaattggaa ttgattgatg
    24181 acgtcttctt cacggtaacc accgagcgtt gaatctgccg ttaaaatgat agctttagcc
    24241 cctgcttcta ctgctttgtt caaaatgaac tcattgaatc tgtcgtcttt actcatatat
    24301 aattggaaaa actgcggtgc gcctggcgct gcatcggctg cgtctttgat tgtcgtattt
    24361 gcataagtgc tgatggaaaa gattgatcca gcagcagcta ctcctttagc tgtatcagct
    24421 tccccttttt catgtgccaa tccttgggcc gctgatggcg cttggataat cggtgtatct
    24481 aattcaattc cgaaaacaga tgtatgcaaa tcggctgagt cgattccgcg taatatccgt
    24541 ggcatgattt tctttgtatt aaaagaagtc gtattttctt tcatcgtcca ctcatcttca
    24601 gaaccaccgc gaatatagcc aaaagctcct gcttccatgc gctcttttac acgaccttct
    24661 agttaggcaa tgtttacaat atcgattgga tgttcttcat tacttgtatg ataagtcata
    24721 gtagatcctt ctttcatctt cttgattaca tataaatcat actaaactta caaaaagtaa
    24781 gcaaacattt actctcagat acttttatcg ctattctttc caaataaatc gacttacaag
    24841 ctgatctact tcttggtttt catgaagcat actatgagag gcattttcac ctgtcactac
    24901 tttttcctct atttcatttc cgcgttgctt caacaacgca tagaccgcta atgcactgtt
    24961 taacggtact gttccatcac tcaagtctgt ttcatctagt tgaccagcaa tcaagaaaaa
    25021 tcgagtggtt ataggaatat taccgatcat ttgctggtaa tcttgatagc ggttagaaac
    25081 gacagcaggc ccctttgcta actcatctgt cagagactgc gcactatcat cgacaaaatc
    25141 attaaaaggc gcgccaattg ctgttaatgt ctgaacttgt ggcaatgacg tatcctgtcc
    25201 atacgttcct aaatagcgta gtgcactaac tcctcccatg gaatgcccca ctatgttgac
    25261 tttatctatg ccgtagtttt ctttcagata caaaagacaa gttttgatcc attctgcttg
    25321 attccactcg ttatttttat tatcttcaaa caatacttgg accatcggat tgtctgcttt
    25381 tccagacaaa tctcctgttg cttgtatttg tccatctgtt cctactgtta aaaccaattc
    25441 ttttactgct tgctgatttt tttccaaacg ccgcaacatc cctttaaagg aattttctgt
    25501 cccgctgtag ccgtggaaaa aaagtgttgg aatagtggtt ttttctatca ctttactgga
    25561 ttctgccgtt ttttctttat cagaaacttc agtagtattt atcttcgtcg tctggcaacc
    25621 acttaacgca aacaaactga taaggactaa agctgctgca gttgcacgtt tgcataaatt
    25681 tttgattggt tctgtcatac acctcttcct ttccatatag aaaaaagaaa gacttgaaag
    25741 gccaatcata tgatcgacat ttcaagtctc tttattaatc gattttatct acttgatcga
    25801 aatcaagttc tgtactggtt tcacgtccaa acatatcgat gttgactttc aatttttctt
    25861 tttctccgtc aacttctgtt acttgtcctt ctaatccagc aaatgcgcct tcgatgattt
    25921 tcacgacttc gccaacttct acttctagat cattttgtcg caggctcata ccgatagaac
    25981 gcaagatatg attgacttct tctggaagta atggtgctgg tttgcttccg gctccgtgtg
    26041 aaccaacgaa tcctgtcaca ccaggtgtgt tgcggacaac ataccatgaa gcgtctgtca
    26101 tgatcatttc aacaagtacg tatcctggga atgttttatg aacgatttct ttttctttcc
    26161 catttttgac ttcagtttct ttttcttcag gaacaacgac acggaaaata aagtcggcca
    26221 ttttcatact ttgcgcacga gattcgatat ttgcttttac tttgttttca tatcctgaat
    26281 atgtatgcaa gacataccag tttttttcaa aagattccat tgaaggctcc tcatttcatt
    26341 gtaaaataaa aaaacctcag tacacccgaa gtttttcttt cgcttcatta tagcactaaa
    26401 agtacgttgt ggctagcgag ttattttaaa atccagccaa ataagctttg gatggctgta
    26461 tccattacgt aaaacatcaa tccgaaaata atagaagttt cgatgactac taacgtatct
    26521 ttacggagtt gttttctgct tggccaagtt acttgtttga tttcatcttt tacgcttttt
    26581 agaaatttca tgagacaacc tcccttgcta ctgtttattt cgtttcttta tgtaatgtat
    26641 attgattaca atatttacaa aacttattga tttccaaacg ttcgccgctt tttccttcac
    26701 tgactgattt tgtgtagttg cgagacccac aaacggaaca agcgagtgct gcttttttct
    26761 ttgccattta cttctgcccc cttgctgaga atcagactta tacttcataa cagtatcacg
    26821 taacttttta cttgtcaatt tgtgaaataa actatctatt gttttggata aaattatgat
    26881 atgattaatt tgaaattaag ctaaaatgag acaattggag gtatagcgat gctattaaaa
    26941 acacttgtat ataagaaaaa agatctgaca accgttacag agactagtac attagaagaa
    27001 gcattaaaaa ttttagaaac ttccggatac cgttgtgtgc cgatcttaga ttcttcaggt
    27061 aatattttcc gtggaaacat ttacaaaatg catatctatc gtcataaagc aaatggcggt
    27121 gatatgacgc ttcctgtcac tcatcttttg aaaaacgcta caaagttcat ttacctggat
    27181 acttctttct tcaaagtatt ctttacgatc aaagagcttc cttatattgc tgtccttgac
    27241 agtgaaaatc atttttatgg tattttgaca catagtacgt tgcttaatat gctctctcaa
    27301 tcttggagcg tagaacaagg aagctatgta ctgacaattg cttccacagg aaagcaagga
    27361 gatttggctg ctattgcaaa aatcatttca aaacacagca gcattgccag ctgtattact
    27421 cttgatatcg aaaaagacga atacattcga cgtacattga tcacgctacc ggctaacact
    27481 gaagcgaaag tatgtgaaac gatcgtcaac cacttagaga aaaagaatta taaagtggta
    27541 gaaattgaaa atttgcaaaa ccaagaagca taatcaaaaa gcgaaaaaag aaaacagcta
    27601 atctgctttc ttttttcgct ttttataatt agacacgctt ttcaaaatca agcgcgcgat
    27661 ctaaataata catcaatggt gctgaaacag ccatgacgat aaactcactt aatgcaagcg
    27721 tgccataggt tgtccaaaat gcttggccac ctgttggaac taacatataa gcaatcagtc
    27781 ccatgctgat ggtaaagaag atcgtgttca atactaaacg catctttaca tttttcactt
    27841 tgttttgcaa taaagctgtc aggcctaaag aaagcaatgt ttggccgcca ccaaaaacca
    27901 catccatgat accaaaacca aagaaggcat tatagacgat gaccccgcct aaaactcccc
    27961 aaagcaattt acggttaaag acaactaaat gattcaaact ttctgaaata cgaaactgga
    28021 tcggccctga ggatacaggc gcaactaaaa tagttaacgc tagataaaga gccatgatga
    28081 tgccatttac aacgattacg gataaccgtt gtctgctttt cgttttttgc attttctctc
    28141 ctcttttctc ctagtttttt taacgcggga tggttgatga accgcggtta tgtgaaacaa
    28201 acaataatta taacagactt ttcatttatt tcaatccgtc ttatctgctt ttaaaaaagc
    28261 aaaagcttaa acaatgtaaa cgtttgctaa aaatcgtggg atatggtata aagtaagtgt
    28321 aaggggtcat aagaattccc agtaaagcag acgaagtagg atctgcaaga acagaattgt
    28381 tgtgaaactt aaataaataa aaaaggatgt gggaatttga gcaacctctt actagagaac
    28441 ggtctagcaa gcagctgaag atctaagtgg acatgccgaa ccttggaact tctccttacg
    28501 taagtaatgg atcatgcgct tgctaggctt ttttgtgttt ttcggtcttc ggaccttttt
    28561 cattttccta gacttctgct ataataacca agaattaatt ttgtaacaga tttttttgaa
    28621 aaaacaagtt tctttcattc aaaaaataga aaaagcttgc taattattgg ttaaccagca
    28681 aacaggagta ttaaaatatc ttgttttatt gaatagcagg aggaaatcat gaaattccat
    28741 tatcatatat tgatcaatcc atcggcaggc agcggaaatg gctataaagt agcagaaaga
    28801 attttaccgg tattaaaaaa taagcatatt gactatacac ttcattatag tgaatacaaa
    28861 ggacacgatg ctgagattgc tgaaactttg gcaaaagaaa cattgattcc ttggatagaa
    28921 gaagaacaga aaacaatcga tactttcccc cttttgatca tcgtaggagg tgacggcacc
    28981 ttacatcagg tacttgatac tttctatcag atggaagtag aattcccagt tgcttatatt
    29041 ccagcaggtt ctggagatga ttttgctcga ggggcaggcc ttccaaaaaa tcccaaaaaa
    29101 ggacttcagc tgattttagc agctcaatca ccagaaaaag tccacataat ggcttatgaa
    29161 gaaaaaataa gtgaaaaaaa aggaatagct gttaataatt tcggtatagg attagatgca
    29221 gctatcgtcc atgcgacaaa tcattcttcc acaaaaaagc gattgaacaa atacaactta
    29281 ggatcatttt cgtatttatt ctctattctc cgtgctttat tcactcaaaa aggatttcca
    29341 attctggtag atgcaggagg aaaacaatta agtttttcaa acgcattttt atgtacagca
    29401 acgaagcatc ctttttttgg cggaggaatc gcgattgttc caactgctga tgcgtctaaa
    29461 ccagtcattg attttgtcgt ggtcgaacga atcaatttct ttaaaatctt gtggctcatt
    29521 cttttactta tacagaaaaa acaattgaaa tcgaaatatt tccatcacta cacaacaaac
    29581 agattacgta tcgtttcaac aacaccgcaa catggtcaag aagatggaga agaaatggaa
    29641 aaacgacctt ttgatatcac aataaccaca actaaacagt tgttttggtg ttaataaaag
    29701 aggttttgtc agaagctaca tctggaacac cgtttattcg gaaaaaagga ctgtgacacg
    29761 acttttgtca cagtcctttt tttactatgc agttaattct ttgcccaatt gggttgccat
    29821 cgatagtttc tttctttacc caaaataaat tggatcattg aaaacaccgc agcaaaagca
    29881 actaagacac aaccattgaa ccaaaaagat tctgcaaatg tttgattgta actgagtgtt
    29941 tcactgatca agttattatt ttgaacaaac caatatgttg gtgtgaatgc cgctattttg
    30001 ctaaccattt ctggcaagta ttctgctggt acaaacaccc caccgataaa gcaactgcct
    30061 gtgataaaaa tatctttgat cccaccgctg gtttctgagt tttttaccaa tgaagtgata
    30121 caagccgaaa agctaatgat cggcaataaa aacaagaaag tatttaaaat atgataccat
    30181 accgttatat cccacgaggt gtggatcact aacagaacca ttagaagtaa gaagccactg
    30241 aacaacagca gcgagtaact aatcaaacta aaggttactt tgcgattcaa gtttcgtttg
    30301 gtaatgggcg cactctggtt tcgtttactg atctctttgc gattaaatgc tagattgatg
    30361 acgctgaaac cgctaaaaat ggatagaaac aacccataag acaagaaatt aaaggttgtg
    30421 cccgtcaaca gctttttcat ccgctgacta tatcccgcac ttagctcaac ttctccagta
    30481 accgagagtg ccatttgtgt ctgttccata gctgcatcga ttgttttatc ttcttcttga
    30541 aacagaatca gtgtttgcaa aaaggtgttc acttgctgtg taacaactgt tttagaaaag
    30601 gcatctgggc gactctgtat cttgatcgtc ggcatctttc ctacttcgac ttgttcggta
    30661 aagtctgcag gcagatgtaa gataatgttt acacgattaa aataaagagc atcatcgatt
    30721 tctttttgtg aggttccatc caatgtaacg actgtttcct tgtcattcaa atatttacga
    30781 aggccatcga ctacaggcga ctcttcttca ctaatcaagg cgattttcgc atcttgcaga
    30841 gaggtatttt caacatcaat attttgcgca aaaaagaatg tggcaacaac agtgataatt
    30901 acacctatca gtaaattcga tttatttgct ttaagcaatg tccaaatcgt tttataaagc
    30961 gtcataacgc acccctcttt ccatccaagc atttcctaac gcaaaaagga aaataaatcc
    31021 gatcaaccat agaagattgg tataaaaact agccaaatca gtgtagaaat aaagtttata
    31081 caaactttcg ctgatcaagt tgacgagatt taattgacca acaatcggaa tatgaagatc
    31141 aatccaatac ttcacttgtt ccgaccccat cataccagca aaaaagctca tcgcaatcgt
    31201 cactgaaatc aagatgctat ccttttgcac cagattcatt tttggtatca aattaccaac
    31261 caatgtacct aacaaaatcg cacacaacga ccccagagcg gtaacaatca tcaaccattg
    31321 ccaacgttca ccaaagtcta cttgatagat aaaacgaaag acagctaaca taatataaat
    31381 ctctgtcaaa acaatcgtaa agcttgctgc caaattagcg attgaaacta acgattgctt
    31441 tctaggaatc aaggacaagc gaataccatt tgacgattga tttgcttgct gatcctgtac
    31501 attgcggacc ccccacatcg tcccgtagag aatcgccatt ccaatcagag tgaagaaata
    31561 aaaacttttg aaactcatat tacgacctgc atgaacttct tgaaaagata cttcttgttc
    31621 aaaaacagtc atgatgggcg cgagatcaac gttctccact tctgccactt tactcgaaat
    31681 tataccaata cgctgtaaaa attgatccat gacgtttttc atcaacgtct gactcattcc
    31741 tgcttgaccc acatggagcg aaacagatga accatcaatg agataaaaac cagccaaatc
    31801 atctgcattt agcttttcat tcgcttctac ttccgatagt tcctgtactt caaataatgg
    31861 tttatcattg acttcgactt gttctaagac tgtggtaaaa ttttccgaaa gcgctgtttg
    31921 atccgctttg attacaattc cagtattaat cgtttcgaga ttgccacctt gatcaatctc
    31981 gccaaaggcc gccataaaca tcaatcctaa aagaattgga aaggccaatg tccaaaacaa
    32041 catggattta tttcgcagca gtatttttgt gcgatattta taaaaatgcc aaaacattat
    32101 ttcccctcct ctagtctctc aaatccttgc cagtaatctc taaaaagaca tcattcaagg
    32161 acgcttcttt ggttgctatt tttccgtaac tgatcttttc ttcttgtaag attgtaagaa
    32221 tcggcaacaa tactgtattt agttcagtag ttgttacttg gagctgacct tttttataag
    32281 cgattccatc agaagctatt gttcgctgac aacacgtttt ctgggagtaa tgggatgtcg
    32341 atcgtcaaac gatccgccgt ccgtaccata tcttttagag attctttggt tcctttagca
    32401 atcacctgtc cttgatccat gatcacgatc tggtcgcaaa gaatttctac ttcttccatg
    32461 taatgtgttg tatagacaat ggttgctcct tgtcgattca gctccttgat actttctaaa
    32521 attttattcc gactttgggg gtctacagct actgtcggct catctaaaaa aattaaccgc
    32581 ggcttgtggg caatcccaca tgcgatgttc aaccgacgtt tcaagccacc actaagttct
    32641 cctggacgaa acgaaacata tttttctaat cccactaatt gaatcacctc ttcaatcaag
    32701 gctttccttt tctctttttc ggaaacatat aaaccgcaaa aataatcgat attttcttgc
    32761 acacttagtt cgtcaaagac cgcaacgtct tgaggaacga ccccaatcat tgccttgaca
    32821 gcataatttt caggagtcat tgttgtcccg aacaatttaa tggttccttt gtcataattt
    32881 aacaaagaaa gcatacagtt gatggcagtc gatttcccac tgccgtttgg tcctaacaga
    32941 cctaagactt ctccttcttg tacttgcaga tcaaaatgat tcaatgctac aaaatctcca
    33001 tagcgtttga ctaatttatc aatttcgata atcatcatga aaaactcctt ccaaatttct
    33061 tgttgatctg actataataa agtgcaagaa aagaaactag tgacgattgg ctaaaccaca
    33121 catgacattt gtcacaatga aggagtctgc tatgcataaa tctcggctac tcaacgaaac
    33181 tagctttcta ctggttatct cattgctttt gctggtaagt caaggattcg ttgctatgca
    33241 agttatctat ttattgatcg ccgttttatt cactggtgtc agttatttac tgcctacaaa
    33301 gccaaattgg attttccaag ttattctatt tcttttatgt gcctttttac ctgatcttgt
    33361 cctgtttctg ccagcgacga tgcgagtgat cgcccctgaa gaaagccacc ttgattactt
    33421 gtttttgtta ggttttttgt tgatttcgac ggttggtaat catcccccca tcaaggtcgc
    33481 ctttgtcgta attttgctgt ttttttcctt ttacttacga aaaaaagatc aacgaacgac
    33541 cgatcttgag aaaaagtaca ttgtctccaa agatactcat tgggaaaaac aacaagagtt
    33601 atcggaacaa aataaagcat tggccctgtc acaagaaaca caattagcct tgcaaattgt
    33661 ggaagaacgg aaccgaattg cccgagacat ccatgacaat gtcggtcatc tgctgtcaag
    33721 tgcgatttta caaattggtg cgcttgaaat gatcaatcaa gaaccaaaac taaaagaacc
    33781 attagaaaat ttaagtgcca ccgttcacac tgggatggat cggattcgtc aaagtgtcca
    33841 tgacctccat gagacatcga tctcttttca acactcctta gagtttctga tcgctgattt
    33901 tccttcttct gttacgattg aaggaaactt gtttgaagga ttgaatgaaa cgcagcaaaa
    33961 ctgcttctta atggtcatca aagaagcctt aaccaacagt atcaaacata gtcatgccaa
    34021 aaccgttgtt ttacattttc gaacgttgcc ggccttttat cgcttgcaaa tcacgaatga
    34081 tggcaccagc ccacaaaaaa attctgctcc cggtattggt ttgaaaacga tgcgtcaacg
    34141 tgttcaagaa caaaagggac aagtccatat tttccaagaa aaccagcaat ttcagttaac
    34201 gatcatttta ccaagggagg gacaccaatg ataacagtag tcattattga gatgatccat
    34261 ttgtgacgaa atcgttacaa accattttag aaagcacgaa agagatccgt gtgttaggca
    34321 ttggtcattg tgccaaggat gcgctagtct tatacgaaac ccatcgtccc gatgttttgc
    34381 tgacggacat ccgcatgcct aaacaaacgg gcatcgatgc tgccaaagaa attttggcta
    34441 aatttcccaa agccatcctt ttgcttttga cgacattcaa agatgaagaa tacatccgcg
    34501 aagcattttc catcggtgtc aaagggtatt taatcaaaca gaacttgcaa gcgattattc
    34561 cttctgtcaa atccgcttat aatggacagg ccgtatttgg taatgaaatc atcgagactt
    34621 tcactcaaat gatgaagaat aaaccgacga ttgatagtca tgcttatgct tcttttagtg
    34681 aacgtgagct tgcaatcatc aaagaagtag ctgccgggaa aaacaataaa gaaattgcag
    34741 atgccttgta cttgagtgac ggcactgttc gcaattacat cagccaatta ctagaaaagc
    34801 tagatttacg ggatcgcacg caattggcta tctattttta tcagcatttg caataagtct
    34861 tatctaacac aaaaaaacct gaatgatgct ccttcgcatc attcaggttt ttttcacatc
    34921 ttctattcaa ttgtcccgca aaccatttcc tcacgattga aagaatcaag gattcgcagg
    34981 gctgccagga ttcgttggat tgttcggcgt gttaggcgga aaaataggcg ccttgtctaa
    35041 cgttttttct agttttgatt cttcacgatc gtctcgttct acatcaggac tttcattcaa
    35101 tttgaattct ttttccatct catctaactt tttaaagtca ttgccagatt cttttgctaa
    35161 tttcgctaat ttatcttcgg tttctttagc cataaagtaa cgcccccctt ttgatttcag
    35221 cttagcatat cacactgaaa aaacaaaaga aaacgctaac caacgatcat ttttagctat
    35281 ttctcatctt taaaatcaag cattttttgc cggtataaaa tcgtagggag aactgttttc
    35341 cataccaatc atcggatcta ctaactggtt atcgatcact tctgctgtaa gaacgaaatc
    35401 tttagaaaca gcaggttcta cctcttcttt cttttcttct ccaacaaatg aagaaaacag
    35461 atctggttcc actgtttcca ttacttggtt tttcgtttca ttcgtcccac tgtcatcttc
    35521 tacaggtagc ttttctttta caacccgtgg ctcttttgta tagttcccat cttcaaatgg
    35581 atcatttccg accaaagaat cttcataagc tgctagtttg gtccggagag tgatattcat
    35641 tttatcatta tccatgatcc ttgatttcaa cgtagtcatc cggcttgctg attcattcgc
    35701 tacacaagtg acataggctt gctcttcccc taacaaaatc aacagttcct tactgcgagt
    35761 cactgccgtg tagagcaaat tacgctgaag catccgctga tattgatgga ccatgggcaa
    35821 aataaccatc ttgaattcac tgccttgtga tttatggatt gagcaacaat aagaaagagt
    35881 gattttattc cattcgtttc ttttataagt gacctcattt gcatcaaact ggataactaa
    35941 ttcatccact ttatcttcag aatcttttgc caagatgata cccgtgattt ctcccatatc
    36001 tccattgaat acattcaatt cgggagtatt gactaattgg aggactttgt ctcctatccg
    36061 ataaacggtg tcgttccaat gtacttcctt ttttccaggt ttccctggat tgaatatctc
    36121 ctgcatcatt ttatttaacg catcgatccc tgcaggtccc cgatacattg gtgctaatac
    36181 ttggatatct tgtgcacgga atcccttatt tttcgctttt tccacaattt tagagatcaa
    36241 gggttcaatt tgataagcat cacttcggaa ataggaacga tctttttgat tctttgtgaa
    36301 atcttttggc agacgtcctt ctttgatctc atgggcaaga ggaataatac tagaaccatc
    36361 accttgccga taaatctgat tgagttccat tttgggaatt tgttcgattt ccaaaagatc
    36421 atggagtact tgaccaggac cgacagaggg aagctgatct ttgtctccta ctaagataac
    36481 ttgcatattc gtcggaatcg ctttgaataa tgtgttagcc agccatgtat cgaccataga
    36541 catctcatca acaatcaaaa gtccgccttc taattctttc gtactgactg aaggtgtttt
    36601 ttcccgtcca ttcagcccca gaagacgatg gatcgtactg gcaggcagac ctgtcgtttc
    36661 gttcattcgt ttagctgctc ggccagttgg tgctgcaagt agaataggaa aaatttcttg
    36721 ggtatatttt gaaggatcca attccagtcc gttcaactct gcaaaaagat tgacgattcc
    36781 gttgatcaca gtagttttcc ccgtacctgg tcctcctgtt aaaataaata gaggggaacg
    36841 gattgcttca gcgatagctt gttcttgcga aggtccatac tgtatgccga atattttttc
    36901 gatacgccga atattcttct gcacttcttt ttcaggataa tggatttctt ttttacgact
    36961 gagaaggcgc tggatcgaat taccgatccc ccattcagaa aagtacaaac tgttttcgta
    37021 aagattagtc tcttcttgtt gtatctttcc ttcttcaaca agttggataa ttacagtagc
    37081 aacctgatca ggctggattt caattgggcg acttgtttct aaaatacgga tcgtttgctg
    37141 aagcaatgtc tccgccggta cgtatgtatc tcctgtttga actgcatgct gaaaaatctg
    37201 atgcaagata gctgctcgaa ttcttctcgg tgaatctgct gcaataccga tttgttcggc
    37261 tagattatct gcacgtttga acccgattcc ttctatgtct tcgactagct ggtacggatt
    37321 ttcttcgatg atatccaaag actcgttctt ataggcctgg tagatactga aagctaactg
    37381 actaccgaac ccgtaacgat tcagtcccat gatcacttga tccatcccgt ggtttagccg
    37441 aatcgtctca gcaagcattt ctctttttgg cttcgtcaaa ccggagattt gttttaatac
    37501 cgaaggatca gcaatgattt tttcgatagc atcttctccc agcaattcta caattttttc
    37561 tgctgttttc ttcccgattc ctgggaattt ttcgctggaa agatacgcta cgatcccatt
    37621 tgcagttgtt ggcttttctt gctcatatct ttcgagttta agctgccttc cgtatttagg
    37681 atgatccact aattctccat aaaaacgata agtctcattt tcttgaatat cgccgaaact
    37741 tccggtgact acaatctctt tttcacggta atcagctgtg gtttcactga tgtgtaccaa
    37801 aagcactttg taaaaattac taggattttg aaaaaaaatc gcggcaactg taccaacgaa
    37861 ataaggcatt tcttctggct gcatcggaag ccgcctcctt cttctatagt aaaggttctg
    37921 gtgctgtttc agttcctaaa aaatctgttt ggttccatac tttcagttca tatggcaata
    37981 atctgcaagg ctcttcagtc tctaaaatcg tcaaactact attgaacaat ccacccattt
    38041 cacgcaactc acttagctct tttcctgtca tccattgaat ggctgcagtt aaagaagctc
    38101 catgtcctac gaataaaagt gggccatctt tatgttgggc aaccgcatct gctacaacag
    38161 tttcgatacg tgtgattgcc gattcaatcg tttctccgtg aaaaggagaa ggatcataca
    38221 gatctaaatg attacgcaaa ttcggcagat tatccggata tttctggtac atttcatcga
    38281 tcgactgacc ttctaaagta cccagcccta gttctcttag cttatctgta taaaaaatct
    38341 ctaccggacg agcaagctct ttgttgatac cttctgctgt atcacgtgct cgctttgctg
    38401 tactggaata aattgcttta aaaggaacat attttacctt tttcccaaat gctttgattt
    38461 cttcgtaact ttgtggcaaa agcggagaat cgccattgct cccttgaaaa cgtctttcct
    38521 gattccattg tgtcttccca tgtcgggtaa aatatagttc catacgcagc aaactcctgt
    38581 ctttctttta ttttactcta taataaactg tctaatccag cttgtcattt tcatagtgat
    38641 gcgtcaattc taaattaggg aatccttgct ggcgaagtgc ttcatacact atcattgcag
    38701 ctgtattcga taaattcaat gagcggacat gctcatcatt catagggatg cgtaaacact
    38761 tttcttcgtt ttcacgcata aatgtttctg gcaaaccggt tgtttctttt ccaaataaaa
    38821 agaagtgctc ttctccatca gcaaaatttt cgtcactata tactttatgg gcaaattttg
    38881 agatcaaatg tagtttacga ttacctaaaa atgttaaaaa agcttctaaa ttactgtggt
    38941 aagtaatatt tacatcattc caataatcca accctgcccg ttttagatgt ttgtcatcag
    39001 ttgaaaaacc tagtggctcg attaaatgaa gcggagtatt cgtggctgca cacgtacggg
    39061 caatatttcc agtgtttgca gggattaatg gttcaaataa aacgatatga ttcatcagga
    39121 tcattcctct catatttatg ttcgtttcta ttttctgaca atttgatttt tgcataaaaa
    39181 aaaacgtatc aactcggtgt cagtcactgc gagtcgttac gttagtgaag ctcttctcac
    39241 taacttttat cagaacagga acctgataaa aaccaatgaa aaaacaactt gttgctaata
    39301 taacaccctc aacttttttt tgcaacctct actcattaaa aactgctaga aaaacgtttt
    39361 ctcttagttc cttttaataa ttctatgtca attgtaatct tcttcaaagg attcttatat
    39421 aagtctgctt tgattcgctc ttctacctgc cattctaaag gtgacatggc caaaagatct
    39481 ttttgatttt cctctggtat ctcaaattca taggttacac gctgacgttc agttaatttc
    39541 attgcttcag caaacttggc tactacacgt tcattggaat aactctgttt ttcaggttga
    39601 ttcggataaa aagcctgacg tagttccttt aaataatttt cttgtggcac caccttcaac
    39661 acttctccat cttctgagag tacacgttgg aattcttggt aatgagaagg cgaaaagata
    39721 tttaaaaccg cgttgaatgt ttgatcagca aacggcaaat tggtcaaatc agctacacac
    39781 caaaatgctt cggcagattg ttctgtagct gcgtagactc cttcttttga aatatcaaat
    39841 ccaacagcat tttgaatctt tttcaatttt gaaagttcat tcaagaagct accttctccg
    39901 cagccaacat ctaatagcga gacttcttca ggtaaatgct gcgcaatagt ctcaataacg
    39961 ggctgataca tgccagattg gatcattcta cgccttggaa cgaacattcc ttgatcgtat
    40021 tctgttttaa ccgcatggga taaaaaataa agtgttcctt ttttggaaag gtcaaaacgg
    40081 tgattatttt tgcatatcaa gccattatca gactttttta cttcttcttg gcaaaccgga
    40141 cagcggaaca gctgatgatt ttctgccaaa aactggcgtc ctcggtcaat tttttttaac
    40201 atagttcccc ctcatttctg ttttatctta ccgttagatg ctcactttgg caactgctaa
    40261 aaatatgata caatgcctag aagaaagtga aagataaagg agaagattag atgatcaaag
    40321 aattttgcgc tgaaaactac acatctattc ctctagcaat tgctagagga gccgatcgga
    40381 tcgaattgtg tgacaactta gcggtcggtg gcacaacccc gagtactggt gtgatcgaag
    40441 aaacgttaag ttatgctggg gaaaaagata tccccgtaat gacgattatt cgtcctagag
    40501 ggggcgactt cgtctataac gatatcgaat tgaaaatcat gcatactgat ttgattgaag
    40561 caaagaaatt agggacggat ggcgtagtat ttggttgtct tactccttca ggctggctag
    40621 acgaagaggc cttagaacta ttgatcgaaa cagcagaagg gttgcagatc accttccata
    40681 tggcttttga cagtattcct gaagatcggc aattcgaagc aatcgattgg ctggtagaac
    40741 atggtgttga ccgtatcttg actcatggcg gtcctgctga caaaactatt gtagaaaatt
    40801 tcccacggct taaagaattg attgcctata cagatggccg cttaatcatt ttgcctggtg
    40861 gtggtgtcac tgcagagaat gcagcacatg tagctaaaga attgaacgta agcgaagtac
    40921 acggaaccaa aatcgtggat cttcagttat aatcttataa acaaaaaaac atttgcaaca
    40981 ggcataatgc ttattgcaaa tgtttttgtt tttttacata aaatagccca taaataaaga
    41041 agcaatattg aaataaatca gtacactcgt caaatcgctc aaagtcgtga taaagggacc
    41101 gcttgctact gctggatcaa atcctagacg atccattagc atcgggatta aactacctgc
    41161 aagattcgcc actgtgattg caaatagcat agccatccct atgacaaacc ccaagataaa
    41221 attatgtttc caaaaaccta cgattagaaa aatcgtgatc cccgtaacag ctcctgtgac
    41281 aacgccggtc aagacttcag ccaaaacaag tcgaacaaat ccatgatctt tctcatcaga
    41341 aatcgcaagt cgacgaacag ccacagctag cgactgggtt ccagcattac cggcagttcc
    41401 tgtaatcagc gaaatgaaga ctgctaaaat actcgcttca cttaccaagt cttcatagtg
    41461 actgattaaa gaagcggtcg acatacctaa aaacaacaga gtgatcagcc aaggcaaacg
    41521 tcgagacgct gcctttactg gattttcatt aatttcttcc acattgaccc cggcaagtcc
    41581 tgaataatcg ctagcagctt catcatcaat aacgtcgatg atatcatcga ctgtgacgat
    41641 tcctaacaaa tgatcatcat aatcggtaac aggaagagct aagaagtcat aatctctaaa
    41701 tgtttgtgcc acatcttctt ggtcgtcgcc tacatgaact gaaagcactc gttcgctcat
    41761 cagatcagaa atcattgcgt cgtcatcatt cacgattagg tcgcgcagag aaataacccc
    41821 tactagctga ccttcttgat taacgacata gatgtaatag attgtttcag ctacatctgc
    41881 ttcgttcttc agcacgtaca tcgcagagcg aacagtttga ttggctacga tcgaaacaaa
    41941 ttcagttgtc atgatcgcgc cagccgtttc atcctcgtaa tggagaagtt ccttgatttc
    42001 actggcatcg tctgccgaca tcaaacttaa atatttagca atttgctttt tatccagcgt
    42061 attaagcaag tcaacagcat tatctgtata catctcagaa agcatatcag ctgcatagct
    42121 aggacgcatt tcatctaggt attctttcat atgttcgttg tcttcttcaa tcacatcgaa
    42181 catatccgct aattctttag gcgacagata ggaatagatc agctgcctgt tctcttctgt
    42241 aagagattgg tagaattgcc cctgctcata gatatgcatc tctaaaaaac tgtttctgaa
    42301 tgcctgaata ttattttccc ttaaatcttg agtcaactgg gcaaatcttt cctctaattc
    42361 ttgattttca tccaaaccaa tctcacctcg ccttattctt caaaccgtct cacaactgcc
    42421 tccatgtctg cggctaaagg ctgcttgaac tccagcaact cttctgtaaa tggatggtaa
    42481 aaacgcagat cataacaatg aagggcttgt ctttttattc ccagatccat tcgcccgcca
    42541 tacatatcat caccgagcag ggcacagcca attgcggaaa aatgaactct tatttgatgt
    42601 gtccttcctg tatgcagctg gatatcaact aacgcgattt ctgttagtcg cttctctatc
    42661 cagtactcag tctgtgccga acgtccttca tcagagacca ttcgcttcaa tagcgaagaa
    42721 taatctcggg cgatcggcaa atcgatatgt ccatgtgccg ataaatctga aagccttcca
    42781 ctgactaagg cctgatattt tttcacaaac ttcttttcac gaagttgcat atctaatttt
    42841 gcgtgcgcaa atccatgctt tgcaaaaagc atcaaaccag atgtatcccg atctagtcgc
    42901 gtcaccacat ggattacttg gttttcgtaa ccttgttttt tataataagc ctttacacga
    42961 ttagccattg tcccatttgg atggtattgg gcaggaatag acgaaacgcc tgctggttta
    43021 tttactacca gaacgtgttc atcttcatac acgatatcga tcggtgtttc atccaaaagt
    43081 acggtttcat gttctccttc agcaggaatc acaatggtta ccttatcatc cttagctaga
    43141 gaaaacaaga cattttctac ttgatcatta actttgattt gaccgccttg aaattttatt
    43201 ttcgctaaca gaccctttga gatccctttt tcttttaaaa aatattttac ttgctgagaa
    43261 tgatctttct cataatccca tgtaaactgc atatcaatcc tcactaataa aggcatcttt
    43321 cacacgatgc caaaaatgca tatgtcgata agaagcaaaa tggatccgtt cttctgctat
    43381 tcgataataa attgagcgga tatttgcttt tgcgacattc aattgatcaa ccgttacaag
    43441 ataatcttct gtattttcca attttatttc tagccattca tcatgggcaa tcacgatcgg
    43501 agaacccaaa gtacgaaaca ctcgattatt cagtgaagca atctctgcca actgaaaggc
    43561 attgatacta ggatggatca cagcaccgcc gacactttta ttatatgctg tcgaaccagt
    43621 aggcgtagaa atcgtcaatc catctcctct aaaactttca aacagctcgt ttttgatgta
    43681 tacatcggct accatcgtac gattggcccg tttaatcgtt gattcattca gtgctaaaaa
    43741 atgctggtcc ggtgtttcat ccaaataact gatccgaaca tccagcaagg gataactaac
    43801 actttgttcc cggttcgttc gtaagctgtc tactagttct tccagctcgt aatcccgcca
    43861 atccgtgtaa aaccctaaat gacctgtatg cacgcccaag aaacgcacat cattcagaca
    43921 atgactgtag tgatggaacg ccgacaataa tgtgccgtct ccgccgactg agatgaccaa
    43981 ttctggctca tgatcatctc gttgaatccc tgcttgttct aaaagtgcgt tcaaacgttc
    44041 tgtcacttct atagtctttg cttctttatt atgaacgatc gctactttca tcccctgcct
    44101 cctctctttc gctttctttc ttcaaaagcg ttcgatagta gacatcatct gattttcctc
    44161 ttccatggga gaataaccgc tgtgcttctt ggatttcttc acggatactg gacatctctt
    44221 catccaactg ataggcagct tctgccgcac gctgaagtcg ttcactcatt tcttctggaa
    44281 aaacgccttg atatttataa ttcagcgaat gctcaatcgt tgcccagaaa ttcatcgcaa
    44341 gagtccgaat ctggatttcc gccaaaattt tcttctcacc gctgatcagc tgtacaggat
    44401 actcgatcac cagatgataa gaacggtagc cacttgcttt tttatttgtg atgtaatctc
    44461 gttcttggag aactttcatg tcttttcttt tacggatgat ctcaacaact tgatggatat
    44521 cttctacaaa ctgacacatg atccttaacc cggcaatatc agacatttct tcttctaaac
    44581 gtcccattgg aatatgccgt aattgtgatt ttgttacaat actatcgact ggcttgactc
    44641 tcccagtgac aaattcaatc gggacatgtc gattttgttc acggaactgt ttgcggatcc
    44701 cccgcagttt cactttcaat tctgatacag tttgttcata tggtgctaaa aatgcttccc
    44761 aatctcgttc catagctgat acctctactt cattaacatt cattgtttat tctaccatat
    44821 atgcaaagtt ttttcgtact cttgatttat gcattgacca aaaaaagaaa attaggcaaa
    44881 atagacaaaa aggagtcgat caaatgacac aaatgcttga aatcgaatat aaatctatgc
    44941 tgacaaagca agagtacgag atattcatcg ctcactatca attaacagat aaagatttcc
    45001 gtgtacagac taatatttat ttcgataccg ttgatgaaca gctgaagaaa caaaattgtg
    45061 gcctacggat ccgtttcgtt ggtcatcaag ctgaatatac attaaaaaca cctgctgaaa
    45121 aagggcgtct cgaaacaacg gataccttta taacagaaga agcagaagca tttatcttcg
    45181 aaaaacgtct gcctcgttca ggcgcagttt ttcaaaaact ttctgatttg aatatcgatc
    45241 ctgcttcatt aatccaaacc ggaaagctta caacaaaacg ggctgaattc cctattgaag
    45301 aaggactttt agctattgat gaaagctggg gagacaatct acacgatttt gaactggaac
    45361 tagaggtagg ggatgcatct gtgggaaaaa ttgcttttat aaatttttta aaacgttttt
    45421 ctttacctta tcgtcctgct aagaacaaga tccaacgtat gcttgaagct aaaaattaga
    45481 aacctttcat tttcacaagg cacttgagtt cattttttta cttttttctg ttaagttata
    45541 ggatgtgaaa gaatctagtc actagttgta tagaatctat tttgggggag attcatatga
    45601 tcgaaatcta tttatttgtt aatcctttag gggaatactg tttcgaaatg gaacaacagt
    45661 tattacaatt tatcgaagaa gagtacggga caccatcaaa agaaaagatg caatttcgct
    45721 ttcttccttt ggtcaatttg cagacaattg gggatgtcat gcaacaaaaa ggaatttctc
    45781 agaacaatct tgaggaacgt aatcacttat tctcaatgac ttattctgca gcattggact
    45841 gcaaagcggc gcagtttcaa ggaaagaaaa aaggccgccg ttttttgatc aaattgcaag
    45901 aagcagtcgg ctgtaatgac ataccatatt ctcaagaact tgctgaatcc atatttgaag
    45961 aaatcggcgg cgatttgaat atgtttaaag aagatcgtca gtctgacttc gttaaagaag
    46021 tattcttttc tgatcaaaaa attgctcggg aaatgggcat cacaaaacac ccttctgcag
    46081 tcgtttacaa ttatgcctgc gaccgtgatt ttggtgtttt agtagaagta aaaggtacaa
    46141 gtagcctttg gagaatcaca gagctgtgta aaacaacaga taactcatat caagttttta
    46201 atggtgaaca tttacataca aatgattctc agttccattc aagaactagc catttacact
    46261 tgctttctaa ttaaaaaaat acgtcgactc ccttacaaga gagccgacgt atttttttcg
    46321 tttctattcg agaaaatcaa aaatagaaag ccttataaac gatcgatcaa ttcttctaat
    46381 tcatttagac gttgttcaaa catcgacatt gcatcttcaa tatatgcagc ctgtgtcata
    46441 tcaactcctg cttttttcat tacttccaca ggataatcgc tgttacctgc ttttaggtaa
    46501 gccaagtagt tctctagtgc ctctggttcc tggtttagta ttttcttcgc cagtgctgaa
    46561 gcagcagaaa agccagtcga gtattggaaa acatagtaat tataataaaa atgcggtatc
    46621 cgtgaccatt cgaatttaat ttctgggtct tcttcgactg ctggaccata atattttgca
    46681 ttcaatttac cataactatc acttaggtat tcactagtca atggcacacc tttttcatct
    46741 tccgtatgca tgaaatgctc gaattcagcg aattgtgtct ggcggaaaac tgttccttta
    46801 aacccatcca agtaatggtt gagtacataa gcccgtacac gagggtcttt ttctgtttcc
    46861 aataaatact ccgttaggat attttcattc gttgtcgaag caatttctgc taaaaagatg
    46921 gagtagtcgc cgtacacata aggctggttc gaacgagtga aataactatg aacactatgt
    46981 cccatttcgt ggacaagcgt aaatagctga tccagcgtat catgccaatt caataaaata
    47041 tatggatttg tgtcatagct tcccgaagaa taagcatcgc ttcgtttccc tttattttcg
    47101 acaacatcga tccaacgttc agagaatgct ttttctacga tggccatgta ttcttcaccc
    47161 attggtttca gtgcttctaa agctttttct tttgcttctt cgtacgtaaa ggtaattgga
    47221 gcttccccta agaccggtgt ataaagatca tacatgtgca gtttttccac ttctaataaa
    47281 cgtttccgta attccatgta tcgatgtaac aaaggcaaat gcttgtttac cacgtctacc
    47341 aaagtatcgt atacactttc aggaatatga ttattgctca aagacgcttc tctggcagag
    47401 ctgtaattac ggactttcgc tttaaaatta tgtcctttta tatgtgtgcc taaagtagaa
    47461 gcaaatgtat ttctaaattg ttcgtaaaca ctgtacaatc ccttaaatgc tgcttcgcgc
    47521 acccttcgat ccgtgctttc tagcaactga ccatacacgc catgagataa ttggactatt
    47581 tcaccatttt ctccttcaat cgttggaaaa actagatctg cattattcaa aacagcaaat
    47641 gtatcacttg aagcatcaaa gatttcacct gctccagcaa gaagagattc ctgctcagca
    47701 gataagacat gggctcgatt atctactatt tgctggatat aatggcgata gacttccaat
    47761 tttggttctt ctttgaaata ttgccaaatc tggtcatctg acaattgcaa tatttctggt
    47821 tcaaaccagg aaacggcttc actaactttc gaaaacagac tgcttgctct tgcataaagc
    47881 gcttggtaat ctgtatttcc agtgtcttga tcgtttttaa ggtgcgcata tacataaatg
    47941 acttcagttt ggcgataaac cctcaatacg aattcaatcg catttaaaaa ttgagaagcg
    48001 ccttgatcaa gtgttccttt gtgtttttca gattgtttta actcttctga taattccaaa
    48061 tatttctcat caaactcttg gtcgcttgaa aagatcttgg tcaagtccca agttaaattt
    48121 tcaggcaatt cttctcgttt tggcaactgc tttacttcca tgaaatccac tccttttctt
    48181 cccttagctc tatctatcaa aatagatcat agtctaacat ccacatgtca cagcatctaa
    48241 cttttctact cattcatgtg tctgcttcca tcaattttag cataactaaa tcttgtttta
    48301 catagaaaac cgattcctag cctattttta tacttactat tttttcaaag aagacaagtg
    48361 tatgcattcg ttaaaaaact gctgatagac catctcttca tcaatcatag gaaaaagcca
    48421 ttccctttta tgttctttta tttggcaaag ccatgagttg aaatcaggaa ctttctggtt
    48481 ttccaaggct tcttcgtaca acattcgata aagaaaaacc tgttcttgta aataaaagaa
    48541 aaaccgactt ttttgataga tccacgatga tagatgcaaa agatgtttat gacgcaagta
    48601 gcattgttct tgtatggata ctgtattctt ttgcttgtga ataagttggc gtgtcagcca
    48661 tttcttccca tcttcactca ctttttctat ttttttcatt tggttcattt taatttcgtt
    48721 actagtgaat atttctttaa ggtccctact agaaaaagtc cagcagctac tgcaaaagga
    48781 aatatgccct gatacagtct ctgtaatatg atgatacaaa taaagctttt gtttcttgag
    48841 atcagctttc cagcaatgca ctcctctttt tctattatag tagcagcaac ttttttctat
    48901 caatgagaat tgcgattgtc caagaaaaga attaccaagt atccaccata cttggtaact
    48961 gttattcaaa taattttggg ttctttcaat aaatctctgg tgagacagtc tagaacattg
    49021 gatttctatt gctagattcg ccaacaaaat atccggcctt tgccgcaacc tcggcaaata
    49081 ggcttccaaa aatactggtt ctactgactg tcccagccaa tccatgaagc attcctttaa
    49141 ctgtaagtgc tcttttgatt ctctttcact aaagaccgaa cagttatctg atttttgatg
    49201 ggcaaaatga gcacattttt tctttccctt tttcaaaatc actctttttc gacagccacg
    49261 acaataatat ttctttcctt tttctgcatg tttagcaaaa cagcacttat tatattcatt
    49321 cattgcaagc agcatttttc tccctctgaa cttatttacg tctaagaatt tatttacacg
    49381 aaaaaagagg gcgtgaaaaa gctattctgc atcaagtaat aagaacagct aaacaaaaat
    49441 agttcccaat atttttcgtt tggttgggct tgttaccgca gatgcaagct tttgaacaca
    49501 tttatacgaa aaaaagactg cgacacaatt tttgtcacag tctcttacta taatgctgat
    49561 ttatacaaaa taaaatttcg ttcgctcgat agcattacgc gccatcagac attgtccata
    49621 ttcattcaat gtttctggtg tacgatcgct cttttcagca aactccaaaa ttcgagcaat
    49681 ctgattctct acatccgctt ggttgagatt ttccatccag aagtgaacga ctaggtaata
    49741 gcgctcttcg aataaataca aatcagtcca agcagactct agttcgacat ctgttgcaag
    49801 ttggatcact tgttcaaaat cttcaaaagc aaaagttgct tgtctttcct gttcttctag
    49861 ggcgcttcca gataattctt cctccggatc gctgccaata atctgctgac gaagaaagtc
    49921 actcacatct tctgaatcaa cagtagaatc ttctgattga gaaatttctt catccggaag
    49981 atttttactg ataaacagtt ctaatccgtc tccttttggc aaaacttgga aagtgacagc
    50041 ttcgcttcct cggaactcct cttcgatatc aacttcttcc aaaatactat aaaagaaatt
    50101 ttcgatttct ttgtgattgc caagtaaatc caaaaatgaa acgccccgtt cctctaaatc
    50161 ttcatgacca attagtacac ggatcgtatt ttcattaata tgttccattt ccattttgct
    50221 acacctcact ttgccacaat gtttaatata gattcattgt agcgaaatca gcttaaatgt
    50281 aaagaaaaaa aatctcgctg ttaagcgaat ttaataaaac cagcggattt ttcaaccttt
    50341 caagctatct tatttaacta taacattttt ggcagacgaa tactatatag ccgacttttc
    50401 agctaatttt ccctctctat ttttcgtgca atcatcatct tctactacct ttttatacat
    50461 ctaatcaaga atactttttg taaaaacaaa aaaacttgga aaaactatct ttgtaatagt
//
LOCUS       DACBYO010000010        50421 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.010, whole genome shotgun sequence.
ACCESSION   DACBYO010000010 DACBYO010000000
VERSION     DACBYO010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.010"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            29..775
                     /locus_tag="IVD26_000568"
     CDS             29..775
                     /locus_tag="IVD26_000568"
                     /inference="COORDINATES: protein motif:HMM:NF016309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078570.1"
                     /translation="MNPKYNTIYKMYLKSRNNRNTLNFSNRYQYYWKSTDVLYEIWCF
                     IKIIRSLSLQGYTPISGWIFENDILSQELPFLHEDTTVVLSKNDIRINLVYNNSMEKE
                     YFSNTLDIPVKTSSKRNKPDIRLDIILQDKYYIGSLIFEVKYKKLDNILDNDKGRQRQ
                     QLMAYKQNTMSSILAFPEILTRSLQAVSAVFALYPSNEGRKKTAPKYYEKEGIFFHLL
                     NPSSDEKELSVKIQTSIEERISLFNQQSRN"
     gene            complement(965..1444)
                     /gene="rlmH"
                     /locus_tag="IVD26_000569"
     CDS             complement(965..1444)
                     /gene="rlmH"
                     /locus_tag="IVD26_000569"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAP6078571.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            1872..3161
                     /locus_tag="IVD26_000570"
     CDS             1872..3161
                     /locus_tag="IVD26_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAP6078572.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(3200..3805)
                     /locus_tag="IVD26_000571"
     CDS             complement(3200..3805)
                     /locus_tag="IVD26_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAP6078573.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(4010..4474)
                     /locus_tag="IVD26_000572"
     CDS             complement(4010..4474)
                     /locus_tag="IVD26_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP6078574.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(4496..4816)
                     /locus_tag="IVD26_000573"
     CDS             complement(4496..4816)
                     /locus_tag="IVD26_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAP6078575.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(4960..6039)
                     /gene="pepA"
                     /locus_tag="IVD26_000574"
     CDS             complement(4960..6039)
                     /gene="pepA"
                     /locus_tag="IVD26_000574"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAP6078576.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            6239..6589
                     /locus_tag="IVD26_000575"
     CDS             6239..6589
                     /locus_tag="IVD26_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP6078577.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            6812..7759
                     /locus_tag="IVD26_000576"
     CDS             6812..7759
                     /locus_tag="IVD26_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP6078578.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(7816..9234)
                     /gene="pepV"
                     /locus_tag="IVD26_000577"
     CDS             complement(7816..9234)
                     /gene="pepV"
                     /locus_tag="IVD26_000577"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAP6078579.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            9383..10228
                     /locus_tag="IVD26_000578"
     CDS             9383..10228
                     /locus_tag="IVD26_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAP6078580.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            10232..10672
                     /locus_tag="IVD26_000579"
     CDS             10232..10672
                     /locus_tag="IVD26_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAP6078581.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            10722..10916
                     /locus_tag="IVD26_000580"
     CDS             10722..10916
                     /locus_tag="IVD26_000580"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078582.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            11052..11665
                     /locus_tag="IVD26_000581"
                     /pseudo
     CDS             11052..11665
                     /locus_tag="IVD26_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(12073..12762)
                     /locus_tag="IVD26_000582"
     CDS             complement(12073..12762)
                     /locus_tag="IVD26_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078583.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(12737..14866)
                     /locus_tag="IVD26_000583"
     CDS             complement(12737..14866)
                     /locus_tag="IVD26_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAP6078584.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(14914..16251)
                     /locus_tag="IVD26_000584"
     CDS             complement(14914..16251)
                     /locus_tag="IVD26_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAP6078585.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(16503..16862)
                     /gene="rplT"
                     /locus_tag="IVD26_000585"
     CDS             complement(16503..16862)
                     /gene="rplT"
                     /locus_tag="IVD26_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAP6078586.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(16915..17115)
                     /gene="rpmI"
                     /locus_tag="IVD26_000586"
     CDS             complement(16915..17115)
                     /gene="rpmI"
                     /locus_tag="IVD26_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAP6078587.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(17187..17711)
                     /gene="infC"
                     /locus_tag="IVD26_000587"
     CDS             complement(17187..17711)
                     /gene="infC"
                     /locus_tag="IVD26_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAP6078588.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            18031..18663
                     /locus_tag="IVD26_000588"
     CDS             18031..18663
                     /locus_tag="IVD26_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP6078589.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(18665..19570)
                     /locus_tag="IVD26_000589"
     CDS             complement(18665..19570)
                     /locus_tag="IVD26_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP6078590.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(19655..20308)
                     /locus_tag="IVD26_000590"
     CDS             complement(19655..20308)
                     /locus_tag="IVD26_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP6078591.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            20630..21574
                     /gene="mvk"
                     /locus_tag="IVD26_000591"
     CDS             20630..21574
                     /gene="mvk"
                     /locus_tag="IVD26_000591"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAP6078592.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            21567..22544
                     /gene="mvaD"
                     /locus_tag="IVD26_000592"
     CDS             21567..22544
                     /gene="mvaD"
                     /locus_tag="IVD26_000592"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAP6078593.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            22557..23642
                     /locus_tag="IVD26_000593"
     CDS             22557..23642
                     /locus_tag="IVD26_000593"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAP6078594.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            23639..24703
                     /locus_tag="IVD26_000594"
     CDS             23639..24703
                     /locus_tag="IVD26_000594"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAP6078595.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(24952..25755)
                     /locus_tag="IVD26_000595"
     CDS             complement(24952..25755)
                     /locus_tag="IVD26_000595"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAP6078596.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25775..26617)
                     /gene="kduI"
                     /locus_tag="IVD26_000596"
     CDS             complement(25775..26617)
                     /gene="kduI"
                     /locus_tag="IVD26_000596"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAP6078597.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(26633..27640)
                     /locus_tag="IVD26_000597"
     CDS             complement(26633..27640)
                     /locus_tag="IVD26_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAP6078598.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(27647..28291)
                     /locus_tag="IVD26_000598"
     CDS             complement(27647..28291)
                     /locus_tag="IVD26_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAP6078599.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(28391..29149)
                     /locus_tag="IVD26_000599"
     CDS             complement(28391..29149)
                     /locus_tag="IVD26_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAP6078600.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(29276..30427)
                     /gene="fucO"
                     /locus_tag="IVD26_000600"
     CDS             complement(29276..30427)
                     /gene="fucO"
                     /locus_tag="IVD26_000600"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAP6078601.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(30509..30820)
                     /gene="rhaM"
                     /locus_tag="IVD26_000601"
     CDS             complement(30509..30820)
                     /gene="rhaM"
                     /locus_tag="IVD26_000601"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAP6078602.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(30822..31667)
                     /gene="rhaD"
                     /locus_tag="IVD26_000602"
     CDS             complement(30822..31667)
                     /gene="rhaD"
                     /locus_tag="IVD26_000602"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAP6078603.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(31681..32937)
                     /gene="rhaA"
                     /locus_tag="IVD26_000603"
     CDS             complement(31681..32937)
                     /gene="rhaA"
                     /locus_tag="IVD26_000603"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAP6078604.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(32934..34394)
                     /gene="rhaB"
                     /locus_tag="IVD26_000604"
     CDS             complement(32934..34394)
                     /gene="rhaB"
                     /locus_tag="IVD26_000604"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAP6078605.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            34547..35416
                     /locus_tag="IVD26_000605"
     CDS             34547..35416
                     /locus_tag="IVD26_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6078606.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(35542..36441)
                     /locus_tag="IVD26_000606"
     CDS             complement(35542..36441)
                     /locus_tag="IVD26_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6078607.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(36606..37430)
                     /locus_tag="IVD26_000607"
     CDS             complement(36606..37430)
                     /locus_tag="IVD26_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP6078608.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(37441..38736)
                     /locus_tag="IVD26_000608"
     CDS             complement(37441..38736)
                     /locus_tag="IVD26_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAP6078609.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(38752..39231)
                     /locus_tag="IVD26_000609"
     CDS             complement(38752..39231)
                     /locus_tag="IVD26_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAP6078610.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(39237..40265)
                     /locus_tag="IVD26_000610"
     CDS             complement(39237..40265)
                     /locus_tag="IVD26_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAP6078611.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(40282..41388)
                     /locus_tag="IVD26_000611"
     CDS             complement(40282..41388)
                     /locus_tag="IVD26_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAP6078612.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(41617..44214)
                     /gene="adhE"
                     /locus_tag="IVD26_000612"
                     /gene_synonym="adhC"
     CDS             complement(41617..44214)
                     /gene="adhE"
                     /locus_tag="IVD26_000612"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAP6078613.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(44519..44899)
                     /gene="yajC"
                     /locus_tag="IVD26_000613"
     CDS             complement(44519..44899)
                     /gene="yajC"
                     /locus_tag="IVD26_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAP6078614.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(44996..46141)
                     /gene="tgt"
                     /locus_tag="IVD26_000614"
     CDS             complement(44996..46141)
                     /gene="tgt"
                     /locus_tag="IVD26_000614"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAP6078615.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            46359..47057
                     /locus_tag="IVD26_000615"
     CDS             46359..47057
                     /locus_tag="IVD26_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAP6078616.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(47225..49864)
                     /locus_tag="IVD26_000616"
     CDS             complement(47225..49864)
                     /locus_tag="IVD26_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP6078617.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
BASE COUNT        14525 a        10763 c         9157 g        15976 t
ORIGIN      
        1 acctataaat gttccaaaat cacttgttat gaaccctaaa tataacacta tatataaaat
       61 gtatttaaaa agtagaaaca atcgtaatac tttaaatttt tcaaatagat atcagtatta
      121 ttggaaaagt acagatgtac tctatgaaat ttggtgcttt ataaaaatta ttagatctct
      181 atccctgcaa ggctacactc caatttctgg atggattttt gagaatgata ttctttcaca
      241 agaattgccg tttttacatg aagacactac cgtagtattg agtaaaaatg atatacgtat
      301 taatcttgta tataataatt ccatggaaaa agaatatttc tccaatacac tagatatccc
      361 agtaaaaacc tcttcaaaac gaaataaacc tgatattaga ttagacatta tccttcaaga
      421 taaatactat atcggaagct taatatttga agtaaaatat aaaaaactag acaatatact
      481 tgataatgat aaaggtaggc aacgtcaaca attaatggct tataaacaaa atactatgtc
      541 aagtattcta gcatttcctg aaattcttac acgttctttg caagctgtct ctgctgtctt
      601 tgctttatat ccttccaatg aaggaagaaa aaaaactgca cctaaatatt atgaaaaaga
      661 aggtattttt tttcacttat taaatccttc atcagatgaa aaagagcttt cagtaaaaat
      721 tcaaacaagt attgaagaaa gaatttcatt atttaatcaa caaagtagaa attaaaaaga
      781 tgaagagcgt ctctttatac aagagagcgc tcttcatctt caattttttg taacaaattt
      841 gaatacataa taaagttatt attatttttt tgaaattctc aacgattttc aagttaactt
      901 ttttatatat aaatttcaat gaaaagctaa cttagtgttc aggagcattc aatcttaaat
      961 atcattattt atgatacgga gcccccgcat tgatccggaa ggcacggtag atttgctcga
     1021 caaggatcag acgcatcaat tgatgtggat acgtcatttt tccaaaagag atctgagcat
     1081 tgcttctttt catgacggct tcgctgagtc ctaaagagcc gccgataaca aaaacaaggt
     1141 ggctttttcc ttggatacct aattggtcga tttgtttagc aaaagattca cttgtaggat
     1201 ttttcccttc aattgctaag gcatagacgt attcttgttc tttgattttc gctaagatcc
     1261 gttccccttc tttttctttt acttgtctca tttgcgcttc gcttaaattc tccggggctt
     1321 tttcgtcagg aacttcgatc aattcgattt ttgcataggc attcagccgt ttgacatact
     1381 cattgatacc ttggatcagg tatttttctt ttaattttcc tactgagata attttgatat
     1441 tcatgttttc tctcctttgg tcttcatgct cactttgttt attataatca attttttcgt
     1501 ctatatgttt attttggcta tttttgttaa aaagatttcc ccaacagtta tgcacaacat
     1561 ccacaggttt atccacagaa aacagtgtta ttttacctta tttcatcaca ttcattaggc
     1621 aaacatacgt tttataagaa tttatccact ttatacacag gctgtggata tgttttatcc
     1681 cttatttttc caatcctatc cgcgtagttt tacacagtat ctgtggaaaa agaaaatcaa
     1741 atattttcat ctgaaaacaa tgatttttcc taaagttttt cataaaaagt tcacagtctc
     1801 aaagtagact aaagtcaaca aataagacta tactaacagt agataaatga atgtaattgg
     1861 aggaggaaca catggataga aaaaatgtga caccaaagat gaaaaaaagt aaaaataata
     1921 gcctctggcg taagttaggt ctggggcttg ttggagggat cgttggagga ctactgacag
     1981 ctggcatttt ttatgcagcg atgggcactg gcaacaatag ttctactgct acaagcggca
     2041 atcagaattc tgccggtgaa acagttgtgg aaaatgtcaa agtcaatgta gattctgata
     2101 tcaccaaagc ggtagataaa gttcaagacg ctgtcgtttc tgttatcaac ttacaaagtc
     2161 aaaaccaatc aagcggtttt ggcggactat tcgggcagca agaagaaagt agcagctcag
     2221 atgatagtaa tttggaagct tatagtgaag gaagcggcgt gatctacaaa aaagacggga
     2281 atactgctta tgtagtcacg aataatcacg tagtagatgg ccagcaaggt cttgaagtct
     2341 tgatgaaaga cggtacgaag gtaaaagctg aattagttgg aacagatgct tattcagatt
     2401 tagcggtgtt gaagatcaat tcagacaaag tcgaaacagt tgcctctttt ggtgactcaa
     2461 gtgctctgaa ggttggtgag cctgcgattg cgattggttc cccactagga tctgaatatg
     2521 caaattctgt cacttcagga atcatttctt ccttgaaccg acaagtgaca agtacgaatg
     2581 aatcgaacga aacagtcaat atcaatgcga tccaaacaga tgcagcaatc aaccctggaa
     2641 attctggtgg tcctttagtt aatatcgaag gacaagttat cggtatcaac tcaagtaaga
     2701 tcgcaagtac ttctgaatct acttctaatg taagcgtaga aggaatggga tttgctattc
     2761 caagtaacga tgtagtgaat atcatcaatc aactggaaaa agacggaaaa gtgacacgtc
     2821 cagctctagg tatcacaatg gtcgacttat ctgccgtttc tactcagcaa caagaacaaa
     2881 tcttgaagat tccttcatct gtaactaacg gtgtcatcgt gacaaatgtc caaacagcta
     2941 caccggctga aaaagctgga ttgaaacaat acgacgtcat tactaagatc gatgacaaag
     3001 aagtttcttc tggtgtagaa cttcaatctg ctttgtataa gaaaaaagtg ggagattctg
     3061 tcaaaatcac ttactatgaa ggctcgaaag aaaaaacaac tactgttgaa ttgacgatcg
     3121 atcaatcggc attaaaacaa aatcaaaata gtgaaaatta ataaaaaaga ggttgtgaca
     3181 aagacttgtc acaacctctt tattttggaa atgcttctcc gactacggca tcctcaggca
     3241 atactaagat tccttttttt gctggagcat ttggcaaatg caattcacga gcggaacaga
     3301 tcattccata gctatctacc cctcgcaaag ttcctggcca gatcatcatt ccatctggca
     3361 tcatagctcc tggttttgca acgacaactt tttgtccagc ttcgatattg ggtgcaccgc
     3421 aaacgatttg caatactgta ccattgtcta cttctgtctc agtaatcgat aaatggtcag
     3481 aatcaggatg tgggacgcat gtttttacgt acccgacaac gatcttcggt tcatgatcag
     3541 cttcaagctg ttcttcgaat cctgcttctt tgatcaatcg attcaatttc gctaattcct
     3601 catctgttaa gcttacttgg ccgttccctt cgattgttag atgatcggag atatggaaaa
     3661 agttccaagc aacaacttga ccttgttcat ctttgatccg agcaacattc catttgcgtt
     3721 caacagtgtt ttctgttcct ttatcgtcgg ctataataac catcaaggtg tctccgacgt
     3781 gtgctttgtt ataagcaaaa atcatgttct ttcctccatt atcctttgct gagatttatc
     3841 ttaacaaaaa attgcattca ctgcatgaaa tttttttcat gctttatttc cgaagaagcc
     3901 tcttctggaa caccatttat tcgtaacaag ggactgtgac aagacttttg tcacagtccc
     3961 tttactgttt tagttaattg attaaaaagg tcgtacaagt tccacttgct taattacttg
     4021 gctgttcttc ttcgtcagaa acgatcaaga catcacaagg tgaatgacgt atcacgtagc
     4081 tggctacact tcctgtcata aagcgttcga ctgcatttag acctgactgc ccaaccatga
     4141 ttagatcgat ctcatatttt tttggcaatt tgactgccat ggattcacga acagaaccat
     4201 atgcaataat tccttctata tttgtgtaat caacagattt cccatattct ttacattctt
     4261 cgatcatttc cttggctgtt tcagtttgct gatcgactag attttgatca ataggtgcat
     4321 agcccataaa gttataaaat tgctgatcga ttacgtttgc tacatatact ttcccattat
     4381 tacggcgagc cacttctacc gcttttttga aagcagcaag tgcttgttca ctaccgtcga
     4441 tacctactaa aatattctta tattcttgat tcatcttgac ccctcctaac agatgtcagc
     4501 cttttgttac actttctagg aacgattcga tttcctgttt tgttttacga tctttattca
     4561 ctagacgacc taattctttt ccgtcttgga tcacgacaaa acttgggata ccaaaaatgt
     4621 tccattcagc ggctacatct atgtacttgt cacggtctac ttcaataaat tgccaatcag
     4681 aaaagtcatt ttcaatttca ggcatttgcg gtttgataaa acggcagtct ccgcaccagc
     4741 cggcagtaaa gaaaaataca ctctttccag tttctacgta gcctgctaat tcttctaaac
     4801 tatttgggat aatcattctt tgtcctctac tttctgttta tgtatttttc aattaaatta
     4861 tacacctttc tttcgaacta acaaacattg atcctctttt tataaaaaaa atctggcaaa
     4921 aagcaatctt ttgccagatt ttatagtttc actatcgcat tattttccgt atacgatcgt
     4981 attcactgtt gatttatcca aacctttcag tgtttgaatc aacatttctc gtgcagcttc
     5041 aaaatcgcga atactgaaca tcgtttgatg cgtatggata taacgtccca ctacgccaat
     5101 cactgtactt gggattcctt cgttttgtgt atgagcagca cctgcatctg taccgccttt
     5161 tgaaacaaag tattgataag ggatattgtt tgtttcagcg atatccagca agtactcgcg
     5221 caaacgagga agcatgatca aacctggatc ttggatacgc atcaatgtac cttctcctaa
     5281 atgtccgaat gtgccatttt tcgtcactgt atcatctgct gcagagcagt ctactgcaaa
     5341 gaacagatct ggcttgaatt tattgacaga agctttagaa ccacgcaagc ctacttcttc
     5401 ctggacattc gcgcctgcaa tcaatgtatg acctaatgtt tcattttgca acgcttctaa
     5461 agcttctaat accattgtac agccatagcg gttgtcccat gatttactga taatattctt
     5521 tccgttggct gttttgatcg tttcagcgta aggaacgatt gtgtctcctg gaaggacacc
     5581 gtaactcatt gcctcttctc ttgattcaaa cccagcatcg aacaaaatat cggttacttc
     5641 tactgatttt tgtccgcttg ttcctcgcaa taaatgtggg ggaacggaag aagaaataca
     5701 tggataattc ttaccagtag aggttttaag tgtaaaacgc tgagcagaaa caacgtaagg
     5761 attccagccg cctagaggta cgactttaaa aagcccgttt tcttggattt gtgtcagcat
     5821 gaatccgact tcatccatat gtgctgcgac cattacacgg ggtgcatccg cttcttcatg
     5881 atggcgcaga ccaaaaatgc cgcccaaacc atctaactgt aactcatcta ccagcggttc
     5941 catatgactt tccatataag cgcgaacatc ttgttcaaaa ccgcttgttc cttgtaattc
     6001 tgttaactct ttgattcgtt gaaatgtttt ttcttccata tgctattcgt ctaaatttca
     6061 gactaaactc ctctcagact tatattgatc tgcggataaa atatgatttt ttctgcagac
     6121 cgatcgtatt tattatagct tattttttct ggtagcggtt atttatttca aagaaaatat
     6181 gagagtgtgg taaaataagc acaaggagta acaagtgaga agaaggaggt atgtccacat
     6241 gtatgaagaa agcgaactaa gctattttaa aggcgggtta gcagttggaa tcggtctagg
     6301 attattgagc ggggtagctt caacgatttg gtatcatcgc aaaaaagtat tgtcagcaga
     6361 ccaagtactt gaaaatatca agtcatcttt tctaaaagaa ggtgcaatcg aaggttcttg
     6421 gatctctttt gaaaaggaac ctattaggaa attcgccgtt cggtcgagtg cttatcgggg
     6481 aggtctttct cgaatagaag atggcgaaac tgtttattat gaatttttag cagatgctca
     6541 tacaggaacc gtattagaaa tttcaagaaa aaaaggtgca acagattaat acgtcaaaaa
     6601 agtgagagaa cgaatacgca cccactattc aaaagagagg tatcatgtcc ttcttttgta
     6661 gtgggtggtt ttttagatag agctttccaa acatatattc cagtattttc tttttaaata
     6721 aatgatattt agcgggaaaa actagcattt cctttgatta tgaggtattt ttaatttagc
     6781 ttttgttttc tatagttaag gagagtgaaa aatggaacaa caagaaaaaa ttgctgttct
     6841 gattccttgt tacaatgagg aagcaacaat ttcaacagtc attgcagact ttaaacgaga
     6901 attaccagaa gcagatattt atgtctatga taataattcg accgatcgaa catacgaatt
     6961 ggccgttcaa ggtggagcaa tcgtaaaaaa agaacctcgt caaggaaaag gaaatgtgat
     7021 ccgccaaatg ttctttgata tcgatgccga ctattattta atggtagatg gcgatgatac
     7081 ttatcctgca gaagctgtac atggtttgct cgagaaatta cgttctggtg aagcagatat
     7141 ggtcattggt gatcgcctat caaatggaac ctactttgat gagaataaga gacctttcca
     7201 cgattttgga aataaccttg ttagaaatac aattactaga atgtataaaa caaaaattct
     7261 tgatgtcatg accggctatc gaggattcaa tcgtatcttt gtcaaaagtt ttcctattat
     7321 gagttctggt tttcaaatcg aaacggaatt gacgatccat gctttagata aaaaattcaa
     7381 gttcgttgaa atcccaatcg attatcgtga tcgtcctgaa ggcagcgaat caaaattgaa
     7441 tacattctct gacggattca aagtgatcat gatgattatt aaaatgttta aagattataa
     7501 gcctttgctt ttctttggga tttggaccat cttcttcttt ttatttggat tggtcacggg
     7561 gattcctgtg attcgcgaat atatgctgac aagctttatt acacgcatcc cttctgcgat
     7621 tttaagtact ggattgatga ctttagcact tctttcatta gtaacagggt tgattttgga
     7681 tacagtcgtc acgaacgcta agaaagaata tgaattgaat ctatatcatg tttatcatga
     7741 ataccacagt agaaagtaaa aaaaggatca agactgcaaa aataatttgc aattcttgat
     7801 cctcttttta attaattatt tcgccaaacg atagatggca tctgcataga ttgctgttgc
     7861 tctgaacaag tcatcaagac tcataaattc gtttgcttga tgcattgtat cagtatatcc
     7921 tgggaacatc gctccataag caacgccacg tttcaacaaa cgtccgtaag ttccgccacc
     7981 gatgatttgt tcgtagcctt tttctccagt gtggtcttca tagacttgca ataatgtagc
     8041 caccaatgga tcatccattg gtacgtaatg tggttccatt acgcgagcac ctcgagtaac
     8101 tgttgcgcct tcttgcccca ctgtttgttc gatgtcactt tgcaatccgt ctactgttac
     8161 accttttgga aaacggaaat tcatattgat gaagttcgct tcctctgtac cattttcttc
     8221 aaaagcaaat agtccagcat tcattgtcaa tttgcccatt ttttcatctt cataagcgac
     8281 tcctagtttt tctccataaa aatcttcatg gacataagca gctgctacat ggataaattg
     8341 tttagcagat cctaggaatt catagttatc taagaacaat gccaagaaag aacctgcatt
     8401 gataccagat tgtgggcttg caccatgtgc gcctttacca actaattcga tttttacata
     8461 cgtattgtcc gcttcaatcg ttccgcttac tggatttgct tcgatgaatt ggtaaaatgc
     8521 ttcttccatc gcgatagctg catctgcact tggtacttga agtgctgcag ttgctgttcc
     8581 tggcaccata ttttcgcgaa gtccggaaac aaaagatttc aagacataat ctcctgcatt
     8641 gtcgcctttg aagcgtaaag ctaaagaaac atttcctttt tcaccattga tgattgggaa
     8701 ttcagcatct ggtgagaaac caaaatctgg ttcttcttca tgttcgaaat aataagccat
     8761 atcgccccag ccgctttctt catcgctgcc gactacgaag cgaacttttt ttgatagttt
     8821 caagtcaagt tctttaatga tcttcatcgc atagtaagct gccatacttg gacctttgtc
     8881 atcgcttgat ccgcgtgcaa agatctttcc atccttgatt actggttcat aaggatctgt
     8941 gtcccagcca tctcctgcag gaacgacatc catgtgtcca aatatcccta gcgtttcgtc
     9001 tccttcgcca agatcaatat gccctgcata gttatcgaca ttttttactt taaatccatc
     9061 acgttcgcca taagctaaca tatgtttcaa tgcgtcgcga ggtccaggtc caaatggtgc
     9121 atctggtgtt acttttgagt catcgcgctc gctgttgaca cgtaaaagat ttttcaagtc
     9181 ttcaagcaag tcttctttac gtgcttctac ttctttttgc caatcaattg tcataaagtt
     9241 aatcctccac ttatttaagt cttcgtgttc atgataccac aaattacaga aaaaaatagt
     9301 tcaaaaaatc tgacaattcc ttttcttatc tgtttttctc taaaaaaaat atacgctata
     9361 atgagtaaaa ggaggttttt agatgctgat aaacgaacaa ctagtgaaaa gagtcatcac
     9421 acctcgtcca aaaatttcac ataaaggaac atttggacgt atcgttttga ttggcggcaa
     9481 tgaacaatat ggcggagcaa tcattatgag tgctttagct gccgtacaca gcggagcggg
     9541 tctcacgact gtagtaactg atgaaaaaaa tcggagtgct cttcacagtc atctgccaga
     9601 agcaatgatt gtagtttgga cggatactga ccagtttctt tccgtaataa agcaagcaga
     9661 tgtactcttg attggtcccg gattgggtac ttcttctaag agtttggaac gtttcaaaca
     9721 agtactagaa aaccaatcaa aagaacaatg gctggtgatt gatggctctg ctttaagttt
     9781 acttgctgct aatcatcttt tgctacccta tcccgaacaa actgtactta cacctcatca
     9841 aatggagtgg caacggttga gttctctacc gatacaagaa caacgggata aagaaaacaa
     9901 aaagaagcaa caggaaatcg gtgctgtgct cgttttgaaa agtcatgaga caaaaattta
     9961 tggtcaccag cacttctaca ccaatccttt aggttctgct gctatggcaa cgggcggcat
    10021 gggtgacact ttagctggga tgatcacagg atttttagcc cagtttcctc aaaatgacca
    10081 aacgattgca gcagctattt atcttcatag tttcattgga gaccagctgg caaaagaaca
    10141 atatattgtt ttgccgacac aaatcagcga agcacttccg aaatggatga attatttttg
    10201 taaaaaatca atggaaaacg aggcatgagt catggagaaa tttacaggtt atgtgcgaga
    10261 acctttttat tatgaaacag atcaaatggg gattattcat cacagcaatt atatccgctg
    10321 gtttgaagag gctcgggtag ccttattggt acatctaggg tttccctata aaaaaatcga
    10381 agaatctggg atcatcatcc ccgttctgga agtaaattgc agctataaag aaatgatcca
    10441 ttacggagaa aaagtgagca tccatccaac tatccaaaag tatacgggga cacggttgga
    10501 ttttagctac gaaattgtgg gaactgaaga caaaaaatta aaaactactg gcagtagtaa
    10561 acactgtttt ttactttctg attcgcaacg attagtgaag ctgagcaaag tcaatccgga
    10621 gttagatcag ttattccaag cgtacgcttc tttggatgat gtaaattctt aataaagacc
    10681 gtctaagcat ttttcttgta ttgtgtcgag tagttcgtat aatgaaaaga aaaaagcagg
    10741 tgatccccat gtatgtcgtt aaagtaatgc acggttacat cgataaaact ggctgtcgca
    10801 ctcgggaaaa aaacttagac aatctgctca ttttcaaaga caaaaaagaa tccgaagctt
    10861 ttgctaaaag aatcggcggt cgtgtcaaac cgatacaaga ggtacgacca gattgattca
    10921 atatttttct tttcgaggct ctaataggca tgcctatcag ggcttttttt gcagactgtg
    10981 tttttatgcc cacacgattt gtaagcgatt tatgttataa tagattatat ctgcatagaa
    11041 aggaaggtta aatggttatc aataatttgc aacagcaagc ttatgaatct atacgtaaac
    11101 aaatcattta ttccgagtta gcacctggaa gtaaaatctc cgataaagtg ttagaagaac
    11161 aactagctat cgggcgtaca ccgattcgag aagcactgat ccaactgcgc aatcaagagc
    11221 ttgtaaaaac cattccacag tccggcactt atgtttcaaa aatcgatatc cgatctgctt
    11281 cattagcccg ttatacgcgg gaaaagttgg aaaaaccgat caggcagtaa tcgctcaaaa
    11341 taaaaaagct ttttttgatt tggatactga ttttcaccga acttgttatg aaattgctgg
    11401 aaaacgagaa atttgggatt ggctagaaag ttatagtacg cacttgaacc gtttcagatg
    11461 gttacgtttg acgatttcag aattagactg gggtcgagta ttagatgaac atcagacaat
    11521 gcttcaatca atgattgatc ataactttga tgaagtcgga tttctttgca cgatgcattt
    11581 acatatgatt atcgaggagc aagaatacgt gattcataat taccccgatt attttgaaga
    11641 tattcaggac agacccatca aataagaggt tttggaatca gcgttttgac ctgagtatta
    11701 gagaaagaaa cggcaaaata gttcctcata ttttgccgtt ttttttgagc taataccgag
    11761 ggtcagctga ttgcacaccg tttattgaga ggttgtgaaa aagctgccct gcatcaagta
    11821 ataagaacag ccaagtaaaa atagcttctt atgtttttaa cttggctgga cttattaccg
    11881 cagatgcaag cttttgaaca ccgttttcca agaggtcgtg agcctgccgt tcatctccga
    11941 gtcacaagga acaatttcaa aaaacagctt ctcatgtttg ttgaatattt tgacttgtga
    12001 ccgaggagtt gacaggagaa catcgtttat tcggaaaaaa aggactgtga cacgactttt
    12061 gtcacagtct ctttatttgt aatctaaatc atactccgta catctttttt ctattttttt
    12121 tatttcttct aagatccctt ggctacgaat ttcattatat ggccaaagta agactgcctc
    12181 taatacataa ggcgaaaaat cgctttgatt catctctttt gaaaaactca tcgctgctat
    12241 ctcgctcaat gcacgaatgt ttgattgatg tgtataaaaa ggcaaccgcc acagcacaat
    12301 tttttcgctt tgcgtataaa ttcccttaac agaagcttcg atgtggtgaa atagttcatg
    12361 tccaataatc aaagcttgcg ctgtttcttt agagatcgaa gctagtcctg aacattttaa
    12421 tttttctaac ggctccgtca tcaatcgaat cccttcatct tctgcataag ttgcaaaagt
    12481 gattcgttcg tttatttgct ctgattcaca ggaaacgatt ggaacagcca tttgttcaca
    12541 aatttctcct acatcggcaa aagggtactt ttttttgatg ctacatgccg tttcgatacc
    12601 acaatcgatt gattgttgta taagaatttt ctgcttggac aaaggaatct ttttccaaaa
    12661 taaatctcgc cgaaactggt agaatcccca aatttcttcg gggatctgtt gtaattcgtt
    12721 tagtaactct tctaacttat gtttgtttga tatttccggc aacgacgatc acttcttcct
    12781 ccggttccat agtagatact tccagatcca tcaaaagctg tagttgttcc agatccgtcg
    12841 ctgtaaaatc agagactctt gctcctaagc agagataaaa ttctggtcgg gcaatcaatt
    12901 cagtttgata aactgccata tcttcccaaa gttgttcgac agctgtcata taattggctg
    12961 cagttgtttt catacatgaa gcatgtccac gttggacctt gataaatcct ttttgatcga
    13021 tgatccgaag acttccagca ttttttgaac gattctgttc gccgcataca taaaagaaag
    13081 gtgtattttc caataagcaa acttcatttt tatttaatcg catatcctct gcagcaagct
    13141 ctagtgcttc ttctgttgtg atctccttgg ttagatcggt tgctttcact tccgtagaac
    13201 cagtagcgat agccgttact tttgaagtct gtggatcgat ttctacgtgg acttcgatcg
    13261 attctggtgt agcgcctgat tcaatcgctt tattcatcgc ttcatttttc aacgatcgta
    13321 tatcttcttt acttggcgaa gggatgatac gttctacaac atctcggacc attgcaagtg
    13381 ctacaccaat agaagaaatc acttcggcgt tttcaggaat cgaatatttc acacccattt
    13441 tattactaaa gtaagtaatc aatgaggcag cgccgccccc tacacctaca agagaaatct
    13501 gatctttctc caagtgatac ttgtctgcca attctaaaat caccggttca atcttagcat
    13561 aggatttttc catgatctgt tctgcgatgt cttcaaccgt cgtatgacaa taatcagcta
    13621 atgcttggat ggcttttcgt gcagatggga catttccata agaaaaatgt tcttcttgca
    13681 ctaatccaag gacattggct gcacatgtat ttgtaatagt cacttcttct ccgtcttcca
    13741 tcactacctt gacgtaatca gcagggtctc cttctttagg agagaaaaat tcaaccttag
    13801 gacctttgat tttttctgtc tccgtaaata ctgcataatc tagaccggca atatgtgcag
    13861 aacgtggacc gacatcgatg attcctgact gattagcccg taccatcgaa ccgcctgcca
    13921 cacctagaac ccgaacatct aatgaagaga tatatgttgg gtggccacct acaattgaat
    13981 aatcgattgc tggacgtcca tttttaatga ccccgatatt ggttgttgtt ccgcctactt
    14041 caaaataaac accattagac gctctcaagt acatcaaaga gcccatgact gatgctgctg
    14101 gaccggaaag catggttaaa acaggtcgtt ttttcatttc attgatttcc attactccgc
    14161 cgtctccgcg cataatcatc aaagaaacat tgacccctgc ttctcgtacg gaatcttctg
    14221 tagaggttgc cgtatctagc atttttggta aaatagatgc attgattgct gctgtccgag
    14281 ttcttcttgt caatccatat aattttgtga tgtcagaagc catcgttgta gggatcgatt
    14341 ttaccgatgc tgcttcataa acaactcgtt ctggttcccc attatctact ccaaatgcca
    14401 tagaagaaac caagacctcc gctctttctc tttctaaaga agaaatcgtt tctgaaacac
    14461 ggtctacatt taagtgtttg acaggtaaga atgcattgac aatctctatt tttttcttat
    14521 tccctaaatc gatatcgttc aatctagttt gtcgttttgc taaaaaacct tctaatccac
    14581 cttttgccat cccgattacg ccgacttttg ctacgtctcc ttcaatcagt gcattagtcg
    14641 cttgtgtggt agaatgtgca acaaacacaa catcttctgg actgatatta ttttcccgca
    14701 aacaattttg aaaagactga acgacacctg cggctactcc acggacatca tcgtgggttg
    14761 ttttcactga agattttccg atgatttcgt gcgtcgcatt atcgattgcg actgctttcg
    14821 tatgtgtacc gccaacatca attcccattc gcacaaaacg tttcattttc ttttcctcca
    14881 ttcatctaat cgtttttatc gacgttttgt ttactaggcg ttcccgtaca ataagaacgt
    14941 gatcaggcat aagatcgctc cgatgatcca accagttggg atggatttct tcatatattc
    15001 tcgagaagtt acttttgtat aacctaatcc ccaagcaacc caagattgtg taatatctaa
    15061 atgctgagga gcaatcgttg tgattgcaaa taacgggaac aaaaaggctg gcgacatcgt
    15121 tggattaaca gctaatacga cagctaaaat agctgagcct gaaccgacta gattcattgg
    15181 accgcggaaa aatcctagtg gtgtcaatat agcaaatacg attgccaaga ctaatggtga
    15241 ttgcggtatc caatctccaa aaatagctga aaaataagga gaagcatacg cagctgaatt
    15301 attgaacatc gctaaggtca tcaagaaacc aaccattggt gcaacatcta ctgcgccatc
    15361 tgtaaataat ttcgcaaact gacgacagat ttctttataa cctccgcgca attttccagt
    15421 aaacagcaat gcccagatac ctgctagaat aaaacctaag atgattggaa gatctaaaag
    15481 aacgacccct aaaactggta ataatacggc taaccatgag atcattggtg cgtcgccacc
    15541 ttcagctggt acgtttgctg ccattgcata gcgtttcttt ttgttcattg atatattagc
    15601 gaccgttagt accacaacta agcttacaat catcccaatc ataccaattt ggaaatagtc
    15661 attataagta tagctttcag ccgctggatt gaaaccagca taaatcgttt gatattgttt
    15721 gaaattgacg atattagcaa agattccagc cataatcgag cccataaatg agaacagtgc
    15781 aaccggtact gaaataccta atgacatcaa gattggcaac acaataactg caatagaaat
    15841 cactggtccg attcctgtca tcgacatgaa tataacagcg gttacaatac atagtaagct
    15901 catcgtgatt cttggcttgt cccctccaag ttcaactacc tttcgaatca gggtagctgc
    15961 gattccgcta tctactagaa cacgcccgaa aaaggcacca aagaagacat ttaccaagat
    16021 cgatttggcg tactcagctg gccccgtcgt atagatatgc gtcaacacat caattactcc
    16081 ttgcccttcc atcgccgggt ttggtgaaaa cgtgtttccg actagcgcta atcccatcca
    16141 tacagtagcc atgatggcaa agccgaccat caagttgtag ccttttacac agtaccagac
    16201 catgaaaaag aatgagataa ctaacaaaat accaataata atatcactca tgttattcct
    16261 ccgtccattt tgtttttctg ataagcaaac taatatatca gtcaaactca ttctaactta
    16321 tgtagttagc gctttcatta aagggtgacc ataaatgttc agttttcaat taaaaaacct
    16381 taattatgct attttagact tatacgttat tgtcctgttt catttgatgg aggattgtaa
    16441 ataaaaaaag aggaaagaac ataacttttc gttatcttct ttcctcttta taattgttta
    16501 gcttatttag ccaaagcttc ttttgcttgg tcagccaatg cagtaaatgc tgctgcatcg
    16561 ttaacagcca agtcagctaa cattttacgg ttgatgtcga tttcagcaac tttcaaaccg
    16621 tgcattaatt ttgagtagct caagccattc atacgagctg ctgcgttgat acgagcaatc
    16681 cacaatttac ggaagtcgcg tttcttttga cgacgatcgc gatatgcgta gttgtatgaa
    16741 ttcattactt gttcttttgc tgttttaaat aaagtgtgtt ttgaaccgta gtaacctttt
    16801 gctaatttta gcactctttt acgacgttta cgagttactg ttccaccttt aacacgtgcc
    16861 atgtataatt cctcctaata aaaataaatc ttcagattct gttatttgta cttcttattt
    16921 catttttgct agttgttggc gaatacgttt gaagtcgcca ctagaaacca tgcttgcttt
    16981 acgcaattga cggcgttgtt tttttgtttt gccgtggaaa cggtgacttg taaacgcgcg
    17041 gaagcgtttc aatccgcctt taccagtacg tttgaaacgt tttgctgatc cgcggtgtgt
    17101 tttttgtttt ggcatgacta tatttcctcc tcaaaatctt tcgttatccg actatcggct
    17161 gtccaacagc cagttagtca ttcaaattac ttactgtcgt ttttcggtgc cagcgtcaag
    17221 aacatgctgc gtccgtccat tttcgctttt tgttccactg ttgcaatatc cgcagtttct
    17281 tcagctaagc gattcaagac tttttgacca atttctttat gggtaatggc acggcctttg
    17341 aaacggatag aagctttcac tttatcgccc ttttccaaga acttacgtgc attacgaagt
    17401 tttgtattga agtcattcaa gtcgatcgta ggacttaagc gaacttcttt tacattgatc
    17461 actttttgtt ttttacgcgc ttcgcggtct ttcttttgtt gttcgaaacg gtatttaccg
    17521 tagtccatga ttcgcgcaac tggtggtttc gcaccagggg caactaacac aagatccaag
    17581 tttgcttgtt ctgcaatatt caatgcttct gcttttgtct taactcctaa ttgctcacca
    17641 tctgaaccga tcaatcgtaa ctctcgtgca cgaatgccgt cgttaaccat catatccttt
    17701 gctatggtca ttcacctcca aatattatga gagaaagaaa agcttaccga ataaacggca
    17761 ataaaaaaac gagttctctt acagaacccg cgcgtacttc acctaataga accagtgaaa
    17821 actatctagc ccagtgacat tatcaactaa ggcgagaagc gggtgcttct gcttttattt
    17881 ctcaaccatc atagtatagc aaaaactaat ctttttgtca atgtttttca tacagtttgt
    17941 cttccttttc tgaaaatgat tagattagca gactttctag cagtgattcc cgcttctttg
    18001 ctatactaaa gaaaaacgag gtgaacccac atgaaaaaaa tcgaacctat tccaccttct
    18061 cttcctcttc ttacaaaggg agagttttat ttagaagatg aggagatctt ctctggtctt
    18121 ctgatcaacg ggggtgacca aagctatctc gatgccaaaa atatggtatt aagagagagt
    18181 catatccaaa aacttacgat gcaaaaaaca gttttacgtc attttgaatg cagtaatgtc
    18241 atttttgaaa aatgtgattt ttccaatctg gagtggattg gtggcagttt ccaccaagtc
    18301 gtgtttcatc aatgtaaatt aacaggtacg aattttgccg aaagttatct tcgagactgt
    18361 actttcactg attgtattgc ttcgatggct tcctttagta gtacaaactt gaaagctgtc
    18421 tccttcgatc attgtcaatt agaagacagc gaattttatg aggtcacttg gaaaaacctt
    18481 tttttgtctg acaatcagtt gaccggttcg aactggtttc gaacttctct gaagggatta
    18541 gactttacga ctaatttctt cacagcaatc gctttatctc aagattcttt ggcgggacta
    18601 atcgtcaacc aagagcaagc acttgtgatc gcccaagccc ttggtttgca gatcaaagac
    18661 tagatcaacg aatccgccgc cacagtgcaa taagcatcca aatagataag accaaactga
    18721 tgatcaaggc gattccccat ccgaaaacgg aatgggtaaa gggtaactgg agattcattc
    18781 cgaagaatcc tgtcacaata gttggaacgg tcaagatcag cgaccagacc gtcaaaaatt
    18841 tcatcgtgtc attcaagttg ttattcagca aattattata agtgccagag agctggtcta
    18901 aaatctgcga agctaagttc gtcatttcaa ctgcttgtcg tgcttcgatc agcgcatcgt
    18961 ccaactcttc tttttccttt tctgacaact tgcgataaat agccaatgcc ttgatttgtt
    19021 ctaaaagtac tacattttgt tttgttcctg taactaagta aaccaaaccg atctctaaat
    19081 ctgaaagttg cagcagattc ttgttcgttg ttttttctct taatttcaga ttaagccgct
    19141 gacgttcact attcacttcc tcgattaaag gaaaaaagga atcagaaatc aaaaacaatg
    19201 tacgaaacaa taaactgtat acactcatgt ctggcattcg ttccaaaagc gatcgaatta
    19261 gtcgaatcac gtactcggta ttcggcgtgg taaatgtaaa caaaccgtct tcttttaaaa
    19321 taaaagcgat aggactagtt tcataatgat tatcgacttt ttgctggtgc ggaacatttg
    19381 atacaagcag taacgcttca tcaaaagaat cgtactctac gcgcgcccgt tcatttttat
    19441 ctagagaata agtcagcatc tcgtcactaa tgccatattc ttcttttaag tttttaacag
    19501 ctagcacatc gttttgctgt acattgatcc aaaaattacg gtcttgatta aaatagtgtt
    19561 tttcccgcat actctatcct cctgacattt gtttccagta taaagaaaaa agtcgctcaa
    19621 ataaaggttt accctttatt tgagcaactg taaatcaaat ggctactttg gtttggcgaa
    19681 tctctgctaa tttttcttcg atcattttca agacttcttc ttttgcttga ggatcttcca
    19741 caaaattata gcggtctcca tcgatttgga tttttggact ttctttgtat tcttcatacc
    19801 attgatcgta acgtctgttc aattctttgt aataatcgta tagacttgga tcaaaggaca
    19861 attgttcata cgaacgacca cgtttttcga tacgctccaa catcgtatca aaagatacac
    19921 gaatatgaac taataaatcc ggatgttttt tatgggcagc atagggaagt tcttccatca
    19981 tgttttccag cagttcatca tacacacgaa cttctgtttc tgttgctctt cctagatctg
    20041 catttagatg gaaaagcagt gaatcttcat aaatcgaacg gtccaataca ttattgtcat
    20101 ctttcattgc ttgtttgatg cttgcaaaac gtttattcaa aaaataaatt tgcagcaaaa
    20161 aagcatactg ttcagggttt gcataaaata agggcaagac ttcattatca tcaatcgatt
    20221 cataaaatgc ctgactatca aagtgttcag ccatcatttc tgttaaactt gattttccgg
    20281 caccaattgt acctgctaaa acgatcacgc tcatttacct ccagctcact tcatcactaa
    20341 atattgtgtt taactccaac ctttttaaat atacccccaa tatctagtag tgtcaattgt
    20401 atttttttct agtcaaagaa gaaaaaaagt caaaaaattc ttaagaaaaa agtgtttttt
    20461 ctttagaaaa cgtattctta gttttacttc tgagatggtt ttagtaaaat aaaggaggaa
    20521 tgttttttga gacccttagt ggacaaaaaa attcgtgaag cagcgcaact cgttttgggc
    20581 gctttatttt ttgcttaaaa atcactttta cgtgagaagg agttagatta tggcaaacta
    20641 tggccaagga gaatcaagcg gaaagatcat attgatgggc gagcacgcgg ttgtttatgg
    20701 agaaccagcg attgcctttc ctttctatgc aacaaaagtc accgcattcc ttgaagagct
    20761 ggatgcaatg gacgatcaac tggtttcttc ctactattca ggaaatttag ccgaagctcc
    20821 tcatgcatta aaaaatatca aaaaattatt cattcactta aaaaaacagc atgacatcca
    20881 aaaaaacttg caactgacca ttgaaagcac gattcctgct gaacgtggaa tgggatcaag
    20941 cgctgcagtc gccacagcag tcactcgtgc tttttatgat tacttagcat ttcctttgtc
    21001 tcgtgaaata ctattagaaa atgtccagct ttcggaaaaa atcgcccacg gtaatcctag
    21061 tggaatcgat gcagccgcta ctagcagctt gcagccgatt tattttacaa aagggcatcc
    21121 tttcgactac ttttctttga acatcgatgc ttttttgatt gtcgctgata caggaatcaa
    21181 aggacaaaca agagaagccg tcaaagatgt cgctcacctc tttgaaaccc agcctcatga
    21241 aactggacaa atgatccaaa aattaggata cttgacgaag caagcaaaac aagcaatcat
    21301 tgaaaattca ccagaaacgt tggcacagac aatggatgaa tcacaatcac ttctggaaaa
    21361 gctgacaatc agcaatgatt ttcttaatct attgatccaa acagcaaaag ataccggggc
    21421 attgggtgcc aaattaactg gcggtggacg cggtggctgt atgattgcat tagcacaaac
    21481 aaaaacaaaa gcccaagaaa tcagtcaagc acttgaagat gcgggtgctg ctgaaacttg
    21541 gatacaagga ttaggagtac atacctatgt ttaaaggcaa agcacgcgca tataccaaca
    21601 ttgctctaat caaatattgg ggtaagaaaa atgaagaact catccttcca atgaacaaca
    21661 gcctttcgtt aacattggat gcattttata cagagacaga agtcatcttt tctgatagct
    21721 atatggtaga tgaattttat ctagatggca ccttgcaaga cgaaaaagca acaaaaaaag
    21781 tcagtcagtt tcttgacctt tttcgtaaag aagccggcct ctcactaaaa gcttcagtaa
    21841 tcagtcagaa tttcgttcct accgcagctg gattagcctc ctctgccagc gggctagctg
    21901 ctttagcagg cgcttgcaat actgctctta agcttggatt agatgatctc tctctttcaa
    21961 gatttgctcg acgcgggtct ggttcagctt gccgaagtat tttcggtggt ttcgtcgaat
    22021 gggaaaaagg ccatgacgac ttaagttctt acgctaagcc agtcccttcc gattctttcg
    22081 aagacgattt agcaatggtt ttcgttttga tcaacgacca gaaaaaagaa gtgtccagca
    22141 gaaatgggat gcgtcggaca gtcgaaacat ccagttttta tcaaggctgg ttagattccg
    22201 ttgaagggga tctatatcaa ttgaaacaag caatcaaaac aaaagatttc caacttctcg
    22261 gagaaacgat ggaaagaaac ggactaaaaa tgcatggaac gactttagct gcccagcctc
    22321 cattcactta ctggtctcct gacagcttaa aagcgatgga tgcggtgcga caattgagaa
    22381 agcaaggcat tccatgctac tttacgatgg atgctggccc taatgtcaaa gttttagtgg
    22441 aaaacagcca tttatctgag gtacaagaaa catttaccaa attatttagc aaagaacaag
    22501 taattactgc acatgctggt ccaggaattg cgattattga ataaagggag atttttatga
    22561 ttgaagtatc tgcaccaggc aaactctata ttgccggaga atatgcagtt gttgaaacag
    22621 gccatccagc agttatcgct gcagtcgatc aattcgtgac agtcactgta gaatctgcac
    22681 gaaaagtcgg aagtatccaa tctgcacaat atagtgggat gcctgtacgt tggacaagac
    22741 gcaacggaga attagtttta gatattcggg aaaatccttt tcattatatc cttgctgcta
    22801 ttcgcttgac tgaaaagtat gcacaagaaa aaaacattct tttatccttt tatgatctga
    22861 aagtaacaag tgagttagac agttcaaatg gccggaaata tggattgggt tctagcggtg
    22921 ccgtgaccgt tgcaacggtc aaagccttga atgtttttta cgcgttgaat ttatctcagt
    22981 tggagatttt caagattgca gcactagcca atttagcagt tcaagataat ggttcctgcg
    23041 gcgacatcgc tgctagctgt tatggtggct ggatcgcttt ctcaaccttc gaccatcctt
    23101 ggctccaaga acaagaaact cagcattcta tcagtgagtt acttgccctg gattggccag
    23161 gtctatccat tgagccattg attgctcctg aagatttacg tttattgatt ggttggacgg
    23221 gtagccctgc ctctacttct gatttggtcg atcaagttca ccgttcgaga gaagataaaa
    23281 tggtggctta tcagcttttc ttaaaaaata gtacagaatg tgtcaacgaa atgatcaaag
    23341 ggtttaaaga aaataatgta acgttgatcc aacagatgat tcgaaaaaac cgacaattac
    23401 tgcatgattt atctgcaatc actggggtcg tcatcgaaac gcctgctttg aacaaattgt
    23461 gtaatttagc tgaacagtat gaaggagccg caaaatcttc tggtgcaggt gggggcgatt
    23521 gcggaatcgt aattgttgac cagaaatctg gcattcttcc tttaatgagt gcatgggaaa
    23581 aagcagaaat cactccactg ccgttacatg tctatagcga tcaaagaaag gaaaaccgat
    23641 gaatcgaaaa gacgaacatg tttcactagc taaagccttt catgataaac aaaaaaacga
    23701 atttgacttc gtacggatca tccataaccc tttgccgcaa atagcagttt ctgatgtcga
    23761 tctaagtaca caggcagttg ggtttacact aagcagccca ttttatatca atgcgatgac
    23821 tggcggaagc gaaaaaacaa aaaaaatcaa ccaagatctt gcaatcgtcg caagagaagc
    23881 agatttgatg attgccactg gttcagtcag cgctgccttg aaagtccctt ctttagccga
    23941 tacttatacg attatgcgac aagaatatcc tcacgggaaa atcattgcca acatcggtgc
    24001 agggacttct gtcgaaagag ccaaagaagc tatccgattg tttcacgcag atgccttaca
    24061 gattcatttg aatgcacctc aagagttggt tatgcctgag ggagaccgtg attttaccaa
    24121 ttggaaagta cttattcaag aaactcaaac agccattgac gtccccctca tcgtaaaaga
    24181 agtcggtttt ggcatgacaa gagaaacgct caatgatcta gctgctttag gagttcatac
    24241 agttgatatc agcggtcgaa gcggaacaag cttcacccag atcgaaaacg cccgtcgctc
    24301 caagcgggaa ctgagttatt tagctgactg ggggcaatcg acagtctctt cattgcttga
    24361 agcaaatgaa gcagacactt ctatggaaat cctagcctcc ggaggtatcc gcaatgccta
    24421 tgacatattt aaagcccttt gtctcggcgc aaatgccgtg ggtacttcag gaaccgtact
    24481 gacgcatctg atgaatcacg gcgtagaaga aactattata ctgatgaagc aatggcaaga
    24541 agagcttcgt ctgctttata ctatggtcgg cgcaacgaat accgcggccc tacaccaaca
    24601 atctctgatc ttttccggac cagtgaagga ttggtgcgaa gcaagaggga tcgacttagt
    24661 gaagtatgga agacgcacag aaaagagcgt gggacaaaag taaagaacac ttttgtctca
    24721 cgctctaaac acgtacaaac ggcggaagta aaagcaactc cttcggaaat aagctgaaat
    24781 tcacaaaaat ttgaaaagca attttcgtga attccttctt atttcttgga gttaaatgct
    24841 tctgtcccag cctctttttt cgaataaatg atgtttaatc agctgtcctt cggtattcgt
    24901 tcaatccgct gatttcacaa cctctccact aaacagtgta ctaaagctct tttaaggttg
    24961 ttttccgata taggcaagta tgcctccgtc cacatacaag acatggccgt taacgaaatc
    25021 agatgcgcta gaagccaaga agacagatgg tccagccaaa tcgattggct cgccccagcg
    25081 tgctgctggc gtacgtccaa cgataaattg atcgaatgga tgacgttcac cgttttcttg
    25141 tgtttcgcgt aatggagcag tttgcggtgt agcaatataa cctggtccaa ttccattaca
    25201 ttggatattg tattgaccgt attcagaagc gatgtttttc gtcagcattt ttaatccgcc
    25261 ttttgccgca gcataagcac tgaccgtttc gcgtcctaat tcactcatca tggagcagat
    25321 attgatgatt ttaccgccgc ctttttcgat catatccgga ataactgctt ttgaaacgat
    25381 gaatggggca tttaaatcca cgtcgattac ttggcggaag tctgccgcat ccatttcgat
    25441 catcggtgtc cgtttgatga tccctgcatt gttgactaga atatcaactg aacctacatc
    25501 ttctttgatc tgttgaacca tcgcttgaac cgcttcttca tcggtcacat cgcagacata
    25561 accttttgca tcgatgcctg cttctttata atgcgctata ccttcatcaa ctgattcttg
    25621 attcaagtta ttaaatacga tttttgctcc tgctgtagct aaagagcgtg caatctcaaa
    25681 tccaatacca tagacagcac cggtgactaa tgctactttt ccatctaaac gaaacatatc
    25741 catactaaat tccatcattt tctctccctt atgcttattt taattgatcc atttgcacca
    25801 tatccatgtc tgtataggtg atattttctc cgcacattgc ccagatgaat gagtaattgc
    25861 ttgtacctac acctgaatgg atcgaccagc ttggcgaaat aatggcttgt tcattgtcta
    25921 caactaaatg ttttgtttca tctggtttgc ccatcatgtg gaacacacgt gtatcttcat
    25981 tggcataatc aaagtagaca taagcttcca tacgacgttc atgtgtatga caaggcatcg
    26041 tattccaagc gcttcctggt tctaaaatcg tataacccat ttgtaattga cagctttcgc
    26101 atacatttgg atggatgtat tggtagattt tacgttcatt cagtgtcagg ccttcaccag
    26161 tctccattgg ttttacttgg tcgatactga tttttacatt tggatattta tgatgagctg
    26221 gaacagaact aatatagaat ttagctgggt tttcagcatc ttgagaagaa aatacaacat
    26281 gtcgtgtttc ttttccgata tagtatccgt cttgtttttt catttcttct ttttgcccat
    26341 cgatctcgat gaatcctggt ccaccgatat tgatcacacc tagttcacga cgctctaaga
    26401 agtaatcaac acctagttct ttgtctaatg tgatttctaa ttctttttca gtaggtgtca
    26461 ctccaccaaa gatcattcga tcgttgtgcg tataagtcaa actgattttc cctggttcaa
    26521 ataccttttc tactaaaaat tcttttctca attgttccgt tgaataatga cggatatctt
    26581 ctggactgtg tgtataacgt gtttccattt cttgcatttt cttctactcc ttctatcgaa
    26641 tgatttttcc agagccgcat gctaaaaatt gtgcgacttc ttcttgacta aattggttgc
    26701 agtccccatg gatcgtatgc ttcaaggcag aagctgccgt agcaaaatca atgatttctt
    26761 gcggagacat attggataaa atcccatgga gcacgccacc tgcaaaagca tctccgccac
    26821 ctactcgatc cacgattggg gtgattctat ggacttggga ttccacatat tcatggttca
    26881 tccacaatgt ccccttcaat tcattttcac ttgctgaatg aacggtacgc ttggtcgaat
    26941 aaaacacctg aatattcggg aacttttcct gcattttttg ataataataa attagaggtt
    27001 gttcttctgc ttctggcgct ttctcgatac ctaacaaata aagagcatcc atttttccag
    27061 ctgagcagat atctactaaa ggtaaaagct gatggattac ttcgctggct tcttgctgtg
    27121 tccataattt tccacgatag ttgatatcga agctgatcag gcagccagct ttttttgcag
    27181 cttctatcac ctgtttcgtc attttttgcc attttttaga caaagctggg gtgattcctg
    27241 aaacatgaaa tatatctatt ccttggaata actcctctag cgaccattcc aaatgatcca
    27301 tttcagcaaa acttgatccg gcacgatcat agatcactga ggcggcgcgt tcgccactac
    27361 cagtttccat ataataagta cctagtcttg atccaccaga taatacctgt ttcgtatcta
    27421 ctccataaca ttgcaagtgc tttttgactg cttttcccaa tgcgttatca ggtacttttg
    27481 tagcaaaaat cgcttcatgt ccgtaattag ctaaagaaat tgctacgttt gcttcccctc
    27541 cgccataatg ggcagcgaat cgttcacttg aatcgatacg ggttccctgc tctgtggaca
    27601 atcgcaacat gatttctccg agtgtcacta cttttcccat aagcagctac ctcttgattt
    27661 ctttcatttt tgctgcatac tgttgcgcga cttccgttac tttgtcaaaa tctcctgtag
    27721 ctgcgggtgc taaaaggttc ccacctactc cgactgttac gacaccagca tcgaaccact
    27781 ctttcatatt gtccagactc acaccgccag ttggcatgat attgacttga ggcatcggcg
    27841 ccttgaaggc agaaatgata cttggtccat aagcgcttcc aggaaatagt ttgacgatat
    27901 ctaccccgct tttcagcgct gttttgatct cggtaatagt catacatcct ggtaagtaag
    27961 gaatttgata cagattgcac atctctgccg tttcttgatc aaaggaaggg ctaacaatat
    28021 actctgcgcc agctaagata gccaagcgag ctgtgacagc gtctaatact gtgcctgcgc
    28081 caatcactat ttctggttgg tctttgtaga atgacaaaag ttctttgatt acttgatctg
    28141 cttgagggac tgtaaaagtc aactcaatac cagttagacc acctttgatg attgcgtggc
    28201 aagcattcaa agcttcttct ttgctttttc cgcgtaccac cgcaatcact ccggcgtttt
    28261 tcaatcgaga taaaatatca atttttttca tcttctccac ctatttccta tttagaaatt
    28321 ttattttata acttggaaat ctatacccat attatacggc agaaaagaaa aattgcaaac
    28381 gcttttttca ttatttttga attctttgct cgatttcgct ttttgtttgc ttgagggcac
    28441 tgattatttg ttcttttgtc tcatctgtta aacgatattt cggcatactt acactaaatg
    28501 caccaatgat ttgttcgttt ttcacgattg aggctcctat acaaaaaata tcacgttcga
    28561 tttcttcatc gtcaaatgcg atgtgggttt cttttaccgt ttggatttcc tttttcaacc
    28621 gtaatgcatt ggtgatcgta tattctgtgt aagggatcaa cggatgcttt tcaagataat
    28681 cagtgtactg ctcttcactg aattctgcta atacggcttt gcccatcgca gaattgtata
    28741 atggtcgggt gattccgatt tttgaagaca tgcggatcgt ttgatgtttt ggatctagtt
    28801 tgttcacgta caagatctca ttgttgtcca atacccctaa gtggatagtc tcatcgatct
    28861 tttgctgcag ctgttctaaa aacggtaaag tcaactctac caaatcgatt tgttcaatgt
    28921 ttttattcgc gtagcgaata agctttgcac ctaaacgata gtttttctct gaatttttat
    28981 ttacgtagcc gatcatcaac aaagtatcta gtattttcaa gactgtagaa gaggtcattc
    29041 ccacaccctt tgcgatcgtc tgcaaagaga catcttggtt ttccgctaaa tagtctagta
    29101 ttttagaggc tttgatcaat acagttccat aaggcttttt attttccata taatattctc
    29161 ctatttcttt ataagaaaaa ttatagcgga aataccatca atttaaaaga gatatccaga
    29221 tataaactac catttctctt tacaggcaat ttaatgttga agatccgctt cgtttttaca
    29281 tcaaactttg atataaagca atgatttctt ctactgtcgt ttctcttgga tttcctggtg
    29341 tgcatacatc tcgcaaagca tcttctgcaa ttgctggaat atctgcttct tttacaccta
    29401 attcagaaat ggtttctggg attccaaccg ctttgctcaa ccgatcgatc tcaccacaag
    29461 ccgcttctct tacatcttct aaagacattt cagctgctcc tttaatccct agaacaagag
    29521 cgatctcacg gtacttttct ccagtatatt ctttgttata tttcatgaca gttggcaaaa
    29581 gtgctgcaca cgctacgcca tgaggaatgt tgtaccatgc acttaacggg tgagccatcc
    29641 cgtgtaccag tcctaaaccg acatttgaga agcccattcc cgcaatatac tgtcctaatg
    29701 ccattttttc tcgcccattt tgatcgccat ctacagaaac ttccaaagaa tggccgatga
    29761 tttcgattgc ttttaaatgc agcatatcag tcatttccca agcgcctttt gtgataaacc
    29821 cttcaatagc atgcgtcata gcatccatac ctgttgatgc agccaatttt ttcggcattc
    29881 ccatcatcat atcgctgtcg atgaacgcga cgattgggat atcatgagga tcaacacaaa
    29941 caaattttcg gtgatttact tcatctgtga tgacgtagtt gatcgttact tctgctgctg
    30001 ttccagaagt cgttggtata gctaatatag gtaaacatgg atttttcgta tcagcaacac
    30061 cttctaaact aatgacgtct gaaaactctg gattcgtcaa aataatccca atggcttttg
    30121 ccgtatcgat tggcgaacct ccaccgattg cgatcaaaca gtctgcctct gcctctttaa
    30181 caaaagccac tccatctttt acattttgga tcgttggatt aggtacgatc ccgtcgtata
    30241 aagcataagc gattgctgct ttatctagaa gttctgttac ttttgttgct ataccgtgct
    30301 cgatcaatcc tttgtcagta atgacagctg ctttgccgaa tcctcgctgc tgaaattcag
    30361 ggacgatcga ctcaatcgct ccttttccaa aatacgatgt ttcatttaaa atcattcgat
    30421 tactcatttt ctattcctcc taatttgtat tttttttcac aataaaaacg aaagaacccc
    30481 aagcaaccgg ttgcccagtt gcttgttgct acagttcaaa gactggcatc aattcccaac
    30541 tgactggaga ggcatctgga tttgtctcca tgatatcttc catgtacttc caccattttt
    30601 gattgataga tgtatttgcc attttttccc ataacttttc atcttcgatc actaagtaac
    30661 caaataacaa acttgtactc ggatcaagat agatcgaata gtcgatgacc ccgtgttcac
    30721 gaagtgctgt acgcatttct ggccaaagtt catcatgtct ttttttgtat tcttcttgtt
    30781 tttctgggta aactttcatg caaaaagctt ttttcaccat gtcagacacc tgctttcgta
    30841 tgaacttcct ccaaataacc tgcttttgga gtgacaccaa acgcatctgc taaatgccac
    30901 aggttttcgt ccgtgattgt ttgcaagatt ggtccttgcg ctttgacgta cgtatagact
    30961 tctgctgcct tttctgctgt ctcgatcaaa ccaaagactt catccatgtc ttttcctgac
    31021 ccgtagattc catgttgtgg ccataaaacc aatcgagttt ctttcatttt ttcagctgtt
    31081 gcttccccaa tctcatttgt tcccggaacc atccacggaa tgatggaaat tccttctgga
    31141 aaaacaacta agcattccgt acacatttgc catagcgtac gactaaagga acgttcgtct
    31201 aattcatgcg taaaactcat cgctaataga tgactagcat ggcaatgcat aacgatccga
    31261 ttatctgggt ctacttctaa acgggcgata tgactcatga aatgacttgg caactcgctt
    31321 gtaggaaggc attcgttttc cagcccccac aaaagttcca gtgttttgcc atcttcagca
    31381 actcgaacga ttccaagatt ctcggcaggt tcgctcgcta catttttaaa atatcttcct
    31441 gaaccagtta caataaaata gcatcctgct aaacggctgg catcaaaaat catcgagatg
    31501 cggcggatca ctttttcagg atccaagaac ggtgtgatct cttcttcttt tagtaaataa
    31561 gaaatattcc cgccatttct ttcatcccat cccaagcgat aaagattcga cgtcgtttcg
    31621 atcatttctt tcacataagg cgcttgtaaa atatctattt ttttcaatat agccacactc
    31681 ctattttctt aattccaaca cgtctttttg atattcctgg acttcttcca gccaatccaa
    31741 accaactgga acttgatttt tgtaacagaa ataattccat acatcggcat acgggaaatc
    31801 tttcaattct tccgtataag ccattcttga agtaaagtca aaagccagct ccatttcttt
    31861 caatcgctca actggttcca gcatagcttt cagcagtgct ttttgtgtat ttctcgtacc
    31921 gatgacccaa gcagcgatac ggttgatcgt tgcatcaaag aaatccagac cgatatttgt
    31981 tttttccaac aattcgttac ggactaattc tttagcgatt tcctgcaatt catcatccat
    32041 caaaaccaca tggtctgaat cccaacgcac tggacgggaa acatgcaaca tgattccttt
    32101 gctgaataaa gctaatgaag ataatttatt ggaaatcact tctgttggat gaaaatgtcc
    32161 agcatctaga caaacaagtt tgtcacgagt caacccgtaa cccatataaa attcatggga
    32221 accgactgta taagcttcag cgcctaaacc aaatagtttg ctttctactg catcttgtac
    32281 ataccgttca tctaactctt ctgtaaaaat ttcatcgagt gattccatta aacgttcccg
    32341 tggggtaaaa cgatcaatcg gattatcttt catcccatca ggtacccaaa agttattgat
    32401 acttgtttgc ccagtttctt tcccaaagta ctccgcgatt ttgcggcttc ttttcccgtg
    32461 ttcgatccag tattcacgaa cttctttatc tggatgagcc aatgtaaagc cgtctttcat
    32521 cattggatgc gaaaagaaag tcggattgaa gtcaagaccg atttcttctt tttttgccca
    32581 ctctacccat ttttcaaaat gtttcggctc aatttcattt agatcgacag attcttctgt
    32641 atccaaatag atagcatgaa ggttcaattt gtgtttgccc ggtatcaacg aataagcctt
    32701 ctccagatct tgtctaagct cttcaggtgt tcgtgcggct cctggaaaat tccctgtcgc
    32761 catgattcca ccggtcaatt cgccatccgg tgtcaagaaa cctttgacat catctccttg
    32821 ccagcaatgc atagaaattt tgatgtcctg tatcttttct agtacagcat ctgtatctac
    32881 accgatagtt gcatattttt cttttgcttg ttcgtaattt ctttcaatcg tgttcatacg
    32941 attactcctt tgattttatt cacgtaccat tccatcgtgt tttgcttatt ttcatctggg
    33001 taaaaagttt cacatggaaa cgactgtttg attacatttc ttgcttgttc tatattcgaa
    33061 aactgacctg tactgagcat ttgcatggca acattcccga ttgctgtggc ttcactaggt
    33121 cctgcttcta caatgattcc ggcataatct gctgtcaatt gattcagtag acgattattc
    33181 gatccgcccc ctacgatgtg cagcttttcc aatttcgttc cagttaagtg ttctactttg
    33241 atcagctctt gtgcgtaaca aagagcaaga ttatcataca cacaacgagc gatagctccc
    33301 gatgagacag ggactggctg ctctgtttca aaacagtatt gctgaatctc ttctatcata
    33361 tttgggggat tcaaaaatcg agggtcattg atttccatca cttgctgcag cggtttttct
    33421 tttgcagcaa gctctgccaa ttccgcataa ctgtactcgt actcttgcat tcgggcaact
    33481 tcctggatca accacatccc catgatgttt ttcaaaaaac gcaccgtgtt atgggcaccc
    33541 cattcattcg tataattttc agaaaaagca ttgcgagaaa cattggcgat ctttgtttca
    33601 atccctaaaa gcgaccatgt cccactgctg atataacccc aacgttctcc ttgacctggc
    33661 gttcctaata cagctgacgc cgtatcatga cttgctactg tgataaaggt cacatctggc
    33721 aaatcatatt ttgaaaattg ttctttttgc agatctccta gtatcgttcc cggctctgtc
    33781 aatggtggaa ataattcctt cgagacaccg attttttcaa gaagttctat ttcccattct
    33841 tttgtccctg cattcagcag ctgcatagta gatgcattag ttttctccgt caccatgtta
    33901 ccagtaaaga cataccctaa ataatcaggt atcagtaaca atttatgtgc ttttgccaaa
    33961 ttttcttttt cttcagcaaa caattggaac aaggtattga aaggctggat ctgaatccct
    34021 gtctgctcat acaacttatc tagagaatag atttcagaaa actgttctac tgctccattg
    34081 gtacgcttgt cccgataagc aatcggatca tttatccgat ccccttgttc atcaatcaga
    34141 cagtaatcga ctgcccatgt atcgatcccc gcaaaaaggc gatcaatccc tgtctgcttt
    34201 aatttttcaa atccaatcaa aatctctttg ataagataat cgatcttcca gcgatcgtga
    34261 ccgtctttgt tccgaaagcc gtttttgaac cggtgtactt cttccaagat caaagaacct
    34321 tttgcatccc tcgtactttt cattagtcgt ccgcttgatg caccgatatc gatggcaaca
    34381 aatgttggat tcatttctcc acctctttta ctttattgtt gattagcact ttattaataa
    34441 agcgttatca tttattaaca atgctatcat aatacagaat cttatatttt gcttcacact
    34501 attttggtat ataattgcat tatcttgaca agttgggagt gtttacatgg attactggga
    34561 aaaagccaac cactcatggt cggaagactc aaaaagagtg atcttgacgc ctacacaaag
    34621 aagcaggaat ttattttttt atatccaaga aatcggttac ttcaaagcac caatccctta
    34681 ctatactgaa cgagcacatt taccttctta cttgataaag tttactttgt ctggcaaagg
    34741 ttcgcttaca tataatgata atcagcaaca gctaaaagct ggagacttat tttttattga
    34801 ctgccaagaa tatcagcgtt atcaaacgat cagcgaagaa ccatgggaaa tggattggat
    34861 ccatttgaat ggtcagaacg tccaatcatt ttatcaggag ttcacaaaag acggccataa
    34921 caccttccat tcaacagggg atccatcaga aaacaagatc caccatttga tcacagaatt
    34981 gatccacatg caacaaggca cgaatgcccg taccgatttc cagtcctctg tagctatcca
    35041 cgagttgctg aatgaactga ttttgcaaaa gtatcagcta gatttcgaag aagaggatat
    35101 tcccgcctac gtttacaaac tgaagcaata cttagacgaa catttcaaag aaacgattac
    35161 acttgatcaa ttagaacaac aattcttatt gaataaatat cagctgagca aagatttttc
    35221 caaatttatc ggttctccac caatcgatta tttgatcagc aaaaaacttt cttacgctaa
    35281 agaccttctt cggtatacag aatttacggt tcgaatgatt tccgaagaaa tagggattga
    35341 gaattttgct tactttagcc gcctgttcaa agcaaaaaca ggactatcgc cgagagactt
    35401 tcgtaaattc agctgattca tataatatgt acgtcatttt ttcaaaatat tttgaaatat
    35461 atagataaaa ataaaataac cgcagtttct gcttctatgt aaacaacagc agctactgcg
    35521 gttatttttt agtgatcatt ctcattgttc atcttcaaaa tgttcataat gaaccaactg
    35581 tttctgtgta tcacgtttca aaaattcttt aggcgttatg ccgaactctc tcttgaatgc
    35641 tttcagaaaa tgcggataag aagaaaaacc acttttacta tatacagcac tagagctgcg
    35701 gtattctcgc aacaagtgct tggcatagat cagctttttc ttcattacat actgatgaaa
    35761 cgtaaatcca gtgtactttt taaattctcg tgtgatatgg tatttgctga caaaaaactg
    35821 cttttccatt tcctctaaag aaagcggatg agataaattt tttgagatat attgtaacat
    35881 ttgttccaca cgctcattag gaactacagc attctgttct tgcgcactct cttctttttg
    35941 tacaacttga ttgagaaaaa tcaagtattc taccagagct tgttcatatt ttatgtcttc
    36001 accgtaaatt tttttatcag gaggatggtc gataaatgat aatttttgct tcaatacttc
    36061 ctgttctatt tgcaatacac gactcctctt ctctcccatt ggttgaaaac aagccgatag
    36121 attagaccat ggcgtggaac gactttctag aaaagaaggg gtgacaaaga tatagacacg
    36181 ctcgaataca tctgaagatt ggcggacgat acgatgcaaa tcattggaat ggatgagcag
    36241 cacacttcct gctttgatcg taaattgtcg tccgttcaaa taaaaagtcg cttctccctt
    36301 taatgtagca tggatctcat agaaatcatg atgatgatag atcgttttat tttggctgac
    36361 gacatctttg acatgataga tttcatactg atcagaaacc atcgtattga cttgttcacc
    36421 gctgattttc ttttggagca tgtgccgcac ctccttttgt tcacttatgc acaattttat
    36481 tataccacgt tttttgtaat caaaaagagc tgcttttata tactcttata aaaaagaaga
    36541 gacgtggcat cttctagccc cgccccctcc attctaaata ttagttaacc aacgtcttct
    36601 ttacattatt caagaagact tcttccataa cgaatcccat catcttttgt ttcttcaaga
    36661 accacataca ggtacggacg attcttcatg atgatttctt tgatttttgt gtactcgatc
    36721 acaccgtctc ccaaatttac cggcacgatt ttttcctgtt cgacacgaaa atctttcaaa
    36781 tgaaccgcac atatcttttc accaaaacgt tcaaaagctt cttctaccaa ttggacttgt
    36841 tcttgataat cactacttgt gatcaaattg gtcggatcta aaatgattcc tagatagtcc
    36901 gaatctactg cttggatcag ctgctctacc cttgctaaag aatacaccgg atgattcaaa
    36961 cctggttcta tccccaccat catttggtat ttttctccag cttttaccaa gcgacggata
    37021 acggacacag cttcagcaaa tgcttcatct gtgaaatttt cttccgtata ttggatttcc
    37081 ggcaaaacac atccagtttc cgaagcaacc atcgacgcac caaaggaaga agcatagcga
    37141 agatactgct cgaactttgt cagcaactct tgtcgtatcg ttaaatctgg atgaatcata
    37201 ttgatatagc aacttaaaat tcctacggtc acttcttgct tttctaaaac tcgtttgaca
    37261 taatttccca tcccagaatt gatctcattt gcgccagaag gtgtttcagg aaacgaaaga
    37321 cctaaggcga gctgcagtgt atgaatccct tgttcttttg ttttttctgc aagatcttct
    37381 atcgtttgga cttcggaaag atcatgtcct ctaattgtaa tgttcaacat aactattctc
    37441 ctaactcagc atattgggta gccacatgac gatttgcggg aagtaagtaa tcaaaaacaa
    37501 gacgactaag ataaccccat aaaaaggaag aagcggtttc agcattgcct ctgcttttac
    37561 gcctcctaca cttgcaccga catatagtcc tgtacctact ggcggcgtga tggagcctac
    37621 acacagattc atgattgaaa acaacccgta atgtacagga tcaaccccta cacttgtgac
    37681 gattggtaaa aatattggtg taaaaatcaa gatagcaggc gccacatcca taaacatacc
    37741 caccagtaat aacacaagat tgactaataa cagaataata aatttattat ccgttacgcc
    37801 cataatcaac gaactaattg cctgaggaat accggtaaac gccatggcga aagacatcat
    37861 ggaagaagta gccaataaga acatgatcgt ccctgacatt gctactgatt gaaacaacat
    37921 attaggtata tcttttagtt ttaccgtttt atagtaaaac atagcaatca acagggagta
    37981 aatgacagct atcgctgaag cttctactgc tgtaaatatc cccgtcaaga taccaccgat
    38041 aatgatgaca atcaatagaa ggctaggaat cgcctctttt attatttttc cagcatgagc
    38101 catctgtcct ttttcgacaa cagggtattt attcttttta gcaacgatga atgctactag
    38161 catgattcct agcgcccaca aagcgcctac gagataacct cccataaaca aagcagagat
    38221 cgaagcacca ccagcaacaa gtgaatacat gataaaagca gtacttggag gaatgaccat
    38281 acctgtcgga gctgacgcga tattgaccgc tgtcgcaaac ttccggtcat atccttcttc
    38341 cacttgctga gggatcaaca ctccgccaat cgcggtagaa gcggcaatgg ccgagctaga
    38401 gatggaacca aataaagcat tccctaacac attcgtatga gccaaagccc ccggcacgcg
    38461 cccgacgaac aacatcgcaa aatccactag tttcttagct atccctccat tattcatgat
    38521 aatgcccgag agaacgaaaa acggaatagc gatcagcgaa aaactattga tacttcccac
    38581 cattttttga gctgaactaa aagcagaaac atcaaacggt ataactaaca ataaagtcat
    38641 catcgatgag aatgcaatac ttatagcaat cggcatccct aatacaagca acacaacaaa
    38701 tacaaaaaat aacactaatc cggcttctat tgccatttta ttcctccatt tttatatttt
    38761 ttcttgaatt gctggcttgt tgcttaatgt atcgattaga ttgatcaggc tatagataat
    38821 gatgagtacc cccgatacag gtactgacag ataaacatat cccataggaa tacttaaaga
    38881 aggcgagatc tgccccattg tcaatgtgac agcattccat ccgccataca ccatgatcat
    38941 cgcagcaaat accagaaata aactttgaac aacaacttct aaaattttac tttttttgcc
    39001 agttaatttt tcacttaaaa ccgttacggc taaatgtgct ttttgtccca caacatacgc
    39061 ggaagacaac atggcaaacc agacaagacc gaatcgaaca agctcttccg tgaccgtatt
    39121 tggatttcct aaaaccgttc tggaaaatac ttgccataaa acaacagcga ccatcccaac
    39181 aagcaaaaca gctcccagga tctctaatac cttgtttaaa atcattttca tcacagctac
    39241 gctccttgct cttggatctt ttgataaagg tctttgtagg taggatcgtt tttgaatata
    39301 tcatgaagtg gggcaactgc ctctcgaaac ggtgtattat ctacatcatt gaattggact
    39361 ccatgttctt cttgtgctaa agctttttct tcttcaattg cttttgcaaa agcttcaatt
    39421 tcaaaaaccg ttgattcttt cgctgcttct tcaatggctt tttcctgctc atcagttagc
    39481 tgttctttga tggcatcatt catgatgatg atatctggca cacgtgtatg ctcatcatag
    39541 gaatagtatt tagccacacc accatgtcca gctgtataca agacaaattc attgttttct
    39601 gatccgttga tcaaattgga ttgaagagac gtgtacactt catcacttcc cataggtacg
    39661 ggcgaaccgc ctaaaagctc taccattttg atagcggttt cgctttgcat cacacggatc
    39721 ttctttccct ccaaatcttc cggcgtatgg atcggaccgt ctaccatata aaagctgcgc
    39781 tgaccagaat cataataggt caatccggta aatcctaaat ttttggtcga ttggtagatt
    39841 ggctccatta tttcttcatt atccatcacc ttaaagaaat gttcttcatc attgaataga
    39901 taaggaactg aaaaaatcga ataatcttta gagaaacttt ccaacgctga ggcacttact
    39961 tttgtgaaat ctactgctcc tgactgtgtc aattcgatca gttcacgttc tccacccagt
    40021 tgtccatctg ggaaatactg gatctgtacg gaaccatctg ttttttcttt tactaaacgc
    40081 ccaaattcat tcattgcatc aattactggc tggctgttgc ttgcataagc aaagcgcaag
    40141 gtaactatct catttacatc tgcatctgcg acagttgcca cactagaatt atttccgcag
    40201 ccgcttagac ctagcagacc taggctaagc gaacttgctg caaacagcag tgatgttttt
    40261 ttcatatggg tttcctttct tttaacaata agagacgagc aattctgtca aacaaagcac
    40321 cgttaacgac tgtccataag gcattgctgt gattccgata ttccgataaa aatctaaact
    40381 gtcccccatt cctgtcccga ttgaaacgtt ttgaacttct cctttttcat cgatttgttc
    40441 aagcaatcct tggatagcac gataagcgac ttctttatat tcttgtggta aataacgttt
    40501 atggaccgct ttcaaaatac cgtaagcaaa tcctgcagtt gcagaagatt ctacgtaaga
    40561 agaaggatca tccaacaacg tatgccataa accgctttca gactgataag tttttaatgc
    40621 acgcacttgt gcttcaagtg tttcgatcaa taatttgcgc aatgcatctt ctttcgataa
    40681 ttctaagatt tcaatgatct ctggaatagc aatcgtcaac cagcagtttc cacgagccca
    40741 aaatgcttcg gcatagttat gatttccttc aaacgtccag ccgtgatacc acaatcctgt
    40801 tcgtttatcc atcaagtatt tgatatggat cataaactgg taacgagctt cttctaaata
    40861 ttctgggcga ttcaacagtt tcccgatttt tgccaaagga agcactgtca tcatcaatgt
    40921 atcgtcccac aactgattct tattttccgg tccatatgtg gcatgctgta acccgtcttc
    40981 atttgtccga ggcatgtcat tcatgaccca ttctgcccat tgttctaaat aaggcaaata
    41041 gcgtgaatct ttcgtgtctt catacaagta agccatagtc aatagcggtg ccattgtatt
    41101 gacgtttttg ggcggagcgc cttcttccat acgatcctca aaccattcat tgaccacttg
    41161 ataagcgcga ggattttttg tcatctggta atttttataa ataccatata gaccgacacc
    41221 ttgtggccaa ttccacactg tccagctttt gtcatctact ttcagtccat caaagtccaa
    41281 caaaaattca ccattatcgt ctttgatcgt tgtcaggttt tcaacgagca ggtcaatttt
    41341 ttctttcact aattctttag gtacaaaaat ctcttcttta ataatcatct ttacgccacc
    41401 tttttaaacg ctttcatttt atatccttaa tatagcagta ataccgtcca ctataaatat
    41461 cgctttttga acaaaaactg tctaaaattg acctaaatgt taaataacaa aagtaacttt
    41521 cagttacttg gaaattaaaa aaagaacttg gagaaacaac gttttccaag ttctttttca
    41581 tctattttct tatctttttt ctacgctttc ttttgcttat ccgttgtaag catcaatgat
    41641 gatctgtttc aattcagaga tcaatggttc tttcggatta gctgtcgtac attggtcttc
    41701 gtaagctaat tcagccatac ggtctacggt tgtatctagt gtttcttgtg tgactccttg
    41761 agcttttaga ctcatgttga tgccgacaga ttttcctaat tcataaacag ccgttgctaa
    41821 agcttcgact aattcctctg ttgtttcgcc tttcagacct aagaattttg cgatatctgc
    41881 gtaatctgta tctgcacgga aatagtcata tttagggaac atcgcatgtt tttgtggatc
    41941 ttttgcatta tagcggataa tatgcggtaa aagaatcgca tttgtccgtc catgagggat
    42001 cccgtattcc ccgccgattt tatgtgcgac tgagtgacaa atacctagga atgcgttagc
    42061 aaacgccata ccagccattg tagaagcgtt gtgcattttt tcacgtgatt ccatatcagg
    42121 tgtttttact gatttttcta aatagtcaaa gactaacttg attgcttgta ggctcaatcc
    42181 acgtgtataa tctgaagcca tgactgaaac ataggattcg attgcatgtg ttaacacatc
    42241 catcccggta tctgctgtga cagatgctgg aactgacatg acgaattgag gatcgacgat
    42301 tgcgacatct ggcgtcaatg cataatctgc taacggatat ttcacatgtg tttcactgtc
    42361 agtgatgacc gcaaatggcg ttacttcaga accagtccct gatgttgtcg ggatacatac
    42421 gaattgtgtt ttttctggtt tgtcgatctt atatgtccgt ttacggatat ccaagaattt
    42481 ttgttttgca ccaaagaaag atgtgtctgg gtgttcatag aacatccaca ttcccttagc
    42541 tgcgtccatt gcagaaccgc ctccaagagc gattactgta tctggcttga agtctgccat
    42601 cagtttcgtt cctgcgtata cggtatttgt cgatgggttc ggttcaacat ctgagaagac
    42661 ttcgatcttc acatcatttt tacgtcgtgc caatacttca cgaactgtat cgcagtaacc
    42721 gaattggacc ataccagggt cacaaacgat catgacacgt tcaacgtttt ccattttctc
    42781 taagtacaat agagagttct tttcaaagaa gatttttggc ggtaatttga accattgcat
    42841 gttatttctc cgtttcgcta cagttttgac attgattaag tttacagcag agacgttacg
    42901 agaaacagag ttcttaccat aagaaccgca tcccaaagtc aatgacggaa tcatttcgtt
    42961 atagatatca ccgatgccgc cttctgcaga tggtgtattc actaaaatac gacaagcttt
    43021 cattcgaaga ccgaatttga catgcaactc ttcgttttct gaatggataa ctgctgtatg
    43081 tcctaatcct ccaagattca acataccttc acacaaatca aacgcatggt ccgtgttgtt
    43141 agctttgatc atggcaagaa ctggagaaag tttttctctt gatagcggat aatctgggcc
    43201 tacgccttcc aattcagcaa tcagcatttt cgttcctttt ggtacactga ttcctgccaa
    43261 ttttgcgatt tccatcgcag aatgtccaac gattgatgga ttgaccgcat attttccttc
    43321 gttcatcact gcatcttcta atttttgcaa ttcatctggt tttacgatat aaacttggtg
    43381 tgcttggaat tctgctttta ctgctgcata gatttcttta tccacgatca cagcttgttc
    43441 agaagcacaa atcattccat tatcaaatgt tttcgaaacg atcaaatcgt tcactgcacg
    43501 tttaattttt gctgtttttt caatataagc tggtacgtta cctggaccta cacctaaagc
    43561 tggttttcct gtagagtaag cagacttgac cattccagct ccacctgtcg ctaagacgat
    43621 cgcgatacct ggatggttca ttagcataga agtcgcttcg atcgaaggat gttcgatcca
    43681 ttggatacaa ttttcaggag ctccggcagc gatagcagca tcacgtacca ctcgtgctgc
    43741 ttctgcagaa gatttttggg cacttggatg gaaagcaaaa acgattggat ttcttgtttt
    43801 caacgcgatc attgatttga aaatcgttgt ggaagtcgga ttcgttgttg gagttactcc
    43861 gcaaaccaca ccgactggtt cagcaatttc aatcaaccct ttttggacat cttcattgat
    43921 cacaccaact gttttatcat gtttgatatt atgccaaata tattcggacg catacatatt
    43981 tttgattgct ttatcttcgt aaacaccgcg gcctgtttcc tctacagcca tcttcgctaa
    44041 tggcatatgt tgatccaaag ctgccattgc catttcatgc acgatatggt ctactttttc
    44101 ttgatcaaag ctttccattt ctttcaatgc tgcatttgct ttttctgcca aatcatcaat
    44161 cattgcttgt acgtcaattg tcttcgtttt ttctttttct attactttag ccatcattat
    44221 cctcctaatg ggtcatggtt atttgttaaa taattcacat gtatatcata caatatttat
    44281 ttttctatgt aaacactttt ttgtgatttt tttcacagtt atttttaaat ataaaattgc
    44341 tttatttaca ggtgtttgta tagaaaaata tataaagtta tttattatta tttatatgac
    44401 acacccgatt attcaatatt gagcaatata tcccatgctc ttatctcttt cttttttgaa
    44461 taaaaaatga ggtaggacat ctttctgccc tacctcgtct ttaaataagc tttgatactt
    44521 atttttcttc cttctcttct gtctcttcca gcgtttctgt tgtttcagtt tttacttcaa
    44581 ctgtctcagc tggttcttct gttgtttcaa cagtagtcgt tgcatcattt gttacgacag
    44641 tccctggttt gaccgttttg attgctgcac gatcgtactc aaggaagatc ccttcgcagt
    44701 ctaaaacaac tgtccgtttg tcattgtcga tttctgaaac aactccatgt aatccgccga
    44761 tcgttacgac tgaatcacct ggtttcatgc tatctaacaa gttttgacgt tcttgctgtt
    44821 gtttcttttg cgaacgtgac ataaaaaacc acattgctaa tagcgcgata aacatcacaa
    44881 gcattggtaa tgttcccatt tttttcacct cactaattct gtatctacaa aaaacacttt
    44941 agcagaaaaa tgctgataac actagttttt tacttaattt ttaaaagatt ttcctttaga
    45001 agctttttgc gttttcttta ttgaacccgt attcttcaaa aaaggcttct ctaaattcaa
    45061 gcaaattatc atccatgatt gcttgacgta cttgtttcat tagattcaac aagaagtata
    45121 aattgtggta agaagtcaaa cgaatcccaa atgtttcatc acatttgatc aaatggcgga
    45181 tataggcacg tgtatagttt ttacatgtat aacaatcaca tttctcatca attggacgga
    45241 aatcatgggc atatttcgca tttttcacta ctagacggcc ttgagaagtc atacatgtgc
    45301 catttcgagc gattcgagta ggcaagacac agtcaaacat gtctactcca cggataacac
    45361 catcgatcaa tgaatcagca gcaccgacac ccatcaagta acgtggtttg ttttcgggga
    45421 tcaacggtgt agtgaattct aatacacgat tcatttctga tttaggttcc ccgacagata
    45481 acccgccgat tgagtaacca gggaaatcca tcccgactag atctttcgcg ctttgacgac
    45541 gaagatcttc aaaccctgct ccttggatga ttccaaataa tccttgacgg tctggattag
    45601 catgagcttt caatcctcgt tctgcccatc gagacgtacg ttctactgat tttttcacgt
    45661 agtcgtaact ttcatcgaat ggtggacatt cgtcaaaact catcatgata tcagagccca
    45721 atttattttg gatgttgatt gctttttctg gtgataaaaa catacgcgaa ccgttcaagt
    45781 gatttttgaa atgcacgcct tcttcttcga tattccgcat atcacttaat gaaaaaactt
    45841 gaaagccgcc tgaatctgtt aaaatcggtt gatcccagtt cataaattta tgcagtccgc
    45901 cagcttcttc tactaagtct tcaccagggc gtagccataa atgatatgta ttacttaaaa
    45961 taacgccagc acccatttct ttcaactctt ctggggacat tgtttttact gtagctaatg
    46021 ttcctactgg catgaacatt ggtgtgggga aagttccgtg tggcgtgatc aattccccta
    46081 aacgcgcgcc agtatgtttt tctttcttga ttaaacgata gcgaatggca ggttgcgtca
    46141 ttcatttccc tactttctat ataaaatatc ttgacaactc ccaccatcat aatcgtttca
    46201 agtgcttttt gcaagttccc tcggcttcct tctactttat ttaatattct tttttttatc
    46261 ctttttttat gaataacaaa aaaaagaaaa acattatgac agaaatattt tttgatacat
    46321 ggtatattgg tgttattaaa gaaaaggagg gaaaaatcat gcaatcttct gcagaattaa
    46381 aacgccaagc aaaagagagt ctaaaaggac gttggggaca agctgtttta ctaaatctaa
    46441 tccctacatt gattggtatt gctactattc ttcttattat gattcctatt atcttgtttg
    46501 ccaccaccat atatgatgga tcagcgagcg tctcagaagc gacaacttca ggaggcggta
    46561 gttcaggagg cggtggcgga attatttcca gcatcattag cgctttgttc atgagcggta
    46621 tttcttggac ttatcttgat attttacgtg gacaaaaaga tcagatcgaa ccattcaaag
    46681 atgcatttcg tggattcaaa ggtttgttta tcggcggagt gatcagctta gctgtgctga
    46741 tctcgatctt tacaacatta tggggtttgc tattagttat tcctggaatc attaaaagct
    46801 attcttattc tcaaagctat tttatttact acgatatcgt ccaagaaaca ggacaaacac
    46861 ctaaagtact ggatacgatc actgcaagtc gaaaattgat ggatggttat aaaggacaac
    46921 ttttctggtt agatctttca tttatcggct ggcatatctt agcattagca actgctggta
    46981 ttggttatct atggctcagc ccatacattt ctgcaacaaa agcagcattt tatgaacaat
    47041 tgccaaaaga tatttaaaag agagtgtgac ttgtgaccga gggggtggca ggagaacacc
    47101 gtttatcgag aggcagtaaa agaaacattc agcccattag caaaaaggag gtgtgacaac
    47161 attcatgtca cacctccttt ttgtatagtt ccagtaaaaa gaaaatcaac ttagaaacag
    47221 ttaatcattc ctcttcttct gcttccggta atcgatggaa cttgatcagt tcattcaccg
    47281 cgattggtac gatagataaa atccctacca agaaccagtg attcaaactg atgtgtacta
    47341 ggccgaatag ttcttgcgta aatggcagca aagcaacagc cgttgtaata gctaatgcca
    47401 gtaacgccat ttctaccaaa gctttattgg tcgctaaatt gactttgaag atcgattggc
    47461 tgctgcgtac attgaacaca tgcagaatcg atgaataagc taagatcaag aatgcaacag
    47521 tttgaccgac atgctgactt gcgtctaccc atgggctgat agtatcgaca taactaccta
    47581 aataataacc aaacaaggtt acgatggtga agacccctgc atttatggca attttttgca
    47641 ataaacctcg agcaaagatc ccttcatttt tcggaatggg tggctgatcc atgatgccgt
    47701 gttccgctgg ctctcttcct aaagcaaatc ctggaagtcc atcagcaact acattgacaa
    47761 acagtagttg cacagctgta aatggtgctc cccatcctaa cagcatcgca atcaaaacaa
    47821 taaagatctc cgaaatatta cagcttagca aaaagttgat agctttacga atattctgat
    47881 aaaccgaacg tccttgactg acagcgtcta cgatcgtcgc aaagttgtca tccgtcaaaa
    47941 tcatatctgc ggcactttgc gccacatctg ttcctgtgat ccccatggca cacccaacgt
    48001 tacttgcttt caacgctggt gcatcattca caccatcccc agtcatcgct acgactgcac
    48061 ccgtacgttg ccaagatttg acgatccgga tcttgtcttc tggcgttacc cgagcataga
    48121 cagagagagc tttgacacgc gcatctaatt cttcgtctga taattgatgc agttctgatc
    48181 ctgaaagtgc ttctgacgga tcattcaaga tacctaattc tttcgctatg gcactggcag
    48241 tcaccacatg atctccagtg atcatgactg ttttgatgcc agcctttttc gctcgcttga
    48301 ttgctccttt actttctgga cgtggtggat cgatcattcc gatcagacca atcaaacgta
    48361 agtctttttc cagtgcttca gaagaaatat cttgcggttc ttcgtcataa gtagcataac
    48421 caacagcaat cactctcagt gcccgtttac caaagcgatc attaacgatc gccgcttgtt
    48481 ctacatcgcc tgaactaaag cgcggagcaa gaacatcgaa tgctcctttg gtgattgaga
    48541 tgtatttttc gcccatttgg tgaactgttg tcatcatttt tcgttcagaa tcaaaaggaa
    48601 gctcgtttac tcgtggatat ttttcttcta attctgcctt tgtatgataa ttctcttcaa
    48661 cagcccttac gatggctact tctgttggat tacctttgat aacaaggtcg tcatcttctt
    48721 gctcgaccgt cacatctgta catagtgcag ccattttcaa tatttccatc gcgctgttcg
    48781 tcattgaatc ttcgatattc gttacttcat cttctttgct ccatacccgg cggacgcgca
    48841 tttcattttg tgtcagcgtt cctgttttgt ctgagcagat aacattagcg gttcctagcg
    48901 tttcaactgc tggcaactgt cggatgatcg catgtttcct cgccatcttc tgcacaccgt
    48961 atgcaagtgt caacgtaaca ataacagtca aggtttccgg tacagctgca acagccaagg
    49021 aaatcgaagt catgaacatc tcaaggagtg gttctccttg cagttcacca atcacaaata
    49081 ctaaagccgc agccgctaaa gcgatcatac tgattcgttt gcctagctga ttcaatcgga
    49141 cctgtaaagg tgttttttgc atagtatttt cgttcaaaag atccgcgatc ttacccattt
    49201 ctgtagccat gccaatggca gtgacgatcg ctttcccacg acctgcagca accgtacatc
    49261 ctttaaatac catattaagt tggtcaccta atgactcatc ttcttcagca ataaatgctg
    49321 catctttttc aactgcttca ctttctccag tcaacgccga ttcttctaca cgtaattgtg
    49381 atgcttcgat caaacgggca tcggcagaaa tagcatcacc ggactctaaa acaagaatat
    49441 cacccactac cagttgctct gactcaacag tggtcacttt gccgtctcgt atgacagttg
    49501 ccgtttgttt attcatatct tgcaaggatt ccagtgcttt ttctgcgttt ccttcttgga
    49561 caatcgccaa taccgagttg atcacaacga tagcgatgat cagcagtcct tcaaataaat
    49621 ccccatgttc tgtagcaaat gcggtataaa aggaaatcac cgctgctaca agaaggatga
    49681 tcgttgtaaa atcggacaag cttcgaaaga attttttgat catcgattct ttcggcgcct
    49741 catcgaattt attcaatccc tgcttttttc gccgttcatc cacttcttgt gaagacaacc
    49801 cagtatctgg atctgcttct gttaccttct ttacttcttc tattgtctgc ttgtattctt
    49861 ccatcctatt cctcctttaa aatcttcgta caaaaaaagg tacttatttt actataacat
    49921 ccttttttta tttacttcaa ataaagggct tatcgattat ttgttaagaa agcgtaaaat
    49981 ttaaagtgct tatatttgca aacgctacca aaggatgcta ttatatagat gtaaggaagg
    50041 aggataccat caaatagaca gaagaatttc tcgatagaac agtgtaagca aacaaagttg
    50101 ttagaagtac aggtttcacc cagacatgcg tgtagagtac aaacctataa atagtgaatg
    50161 cgtatggatg tttggatcac gaagtatccg aaacaagaag taatgcgata cgtaacaatt
    50221 gaataacgta aacgtctgaa aattgaatag gaacaagaga tgtttcaaat gttgaagatg
    50281 taacgaaaac aaaatttttg tttaacatga agaaattcaa caccgtgctt tgcatgtatg
    50341 atggaaagtt acaatcattt ctgtttattt gaatccttcc gaggtacaag aaagccgagc
    50401 ttatcgagag ctcggctttt t
//
LOCUS       DACBYO010000011        45750 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.011, whole genome shotgun sequence.
ACCESSION   DACBYO010000011 DACBYO010000000
VERSION     DACBYO010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.011"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..1008)
                     /locus_tag="IVD26_000617"
     CDS             complement(<1..1008)
                     /locus_tag="IVD26_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP6078618.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="IVD26_000618"
     CDS             complement(1188..1532)
                     /locus_tag="IVD26_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP6078619.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="IVD26_000619"
     CDS             complement(1525..1959)
                     /locus_tag="IVD26_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAP6078620.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="IVD26_000620"
     CDS             2097..2834
                     /locus_tag="IVD26_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6078621.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="IVD26_000621"
     CDS             2827..4038
                     /locus_tag="IVD26_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6078622.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4245..5024
                     /locus_tag="IVD26_000622"
     CDS             4245..5024
                     /locus_tag="IVD26_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAP6078623.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="IVD26_000623"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="IVD26_000623"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAP6078624.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="IVD26_000624"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="IVD26_000624"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAP6078625.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="cpaF"
                     /locus_tag="IVD26_000625"
     CDS             7740..8669
                     /gene="cpaF"
                     /locus_tag="IVD26_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAP6078626.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /locus_tag="IVD26_000626"
     CDS             8626..9675
                     /locus_tag="IVD26_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAP6078627.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /locus_tag="IVD26_000627"
     CDS             9672..9950
                     /locus_tag="IVD26_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAP6078628.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /locus_tag="IVD26_000628"
     CDS             9925..10395
                     /locus_tag="IVD26_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAP6078629.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10412..10714
                     /locus_tag="IVD26_000629"
     CDS             10412..10714
                     /locus_tag="IVD26_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078630.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10731..11102
                     /locus_tag="IVD26_000630"
     CDS             10731..11102
                     /locus_tag="IVD26_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAP6078631.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /locus_tag="IVD26_000631"
     CDS             11074..11433
                     /locus_tag="IVD26_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078632.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="IVD26_000632"
     CDS             11605..12612
                     /locus_tag="IVD26_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6078633.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="IVD26_000633"
     CDS             12637..13821
                     /locus_tag="IVD26_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAP6078634.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /locus_tag="IVD26_000634"
     CDS             complement(14258..15841)
                     /locus_tag="IVD26_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP6078635.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16419..16562)
                     /locus_tag="IVD26_000635"
     CDS             complement(16419..16562)
                     /locus_tag="IVD26_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAP6078636.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="IVD26_000636"
     CDS             complement(16785..17264)
                     /locus_tag="IVD26_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP6078637.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="IVD26_000637"
     CDS             complement(17337..17621)
                     /locus_tag="IVD26_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078638.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="IVD26_000638"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="IVD26_000638"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="IVD26_000639"
     CDS             complement(17965..19251)
                     /locus_tag="IVD26_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAP6078639.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="IVD26_000640"
     CDS             19389..20060
                     /locus_tag="IVD26_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAP6078640.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="IVD26_000641"
     CDS             20026..20514
                     /locus_tag="IVD26_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAP6078641.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="IVD26_000642"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="IVD26_000642"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAP6078642.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="IVD26_000643"
     CDS             21475..22239
                     /locus_tag="IVD26_000643"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAP6078643.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="IVD26_000644"
     CDS             22472..24685
                     /locus_tag="IVD26_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAP6078644.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /locus_tag="IVD26_000645"
     CDS             24696..25142
                     /locus_tag="IVD26_000645"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAP6078645.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="IVD26_000646"
     CDS             25313..26572
                     /locus_tag="IVD26_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAP6078646.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="IVD26_000647"
     CDS             complement(26661..27608)
                     /locus_tag="IVD26_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAP6078647.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /locus_tag="IVD26_000648"
     CDS             28002..29294
                     /locus_tag="IVD26_000648"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAP6078648.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="IVD26_000649"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="IVD26_000649"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAP6078649.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="IVD26_000650"
     CDS             31187..32062
                     /locus_tag="IVD26_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP6078650.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="IVD26_000651"
     CDS             32328..34211
                     /locus_tag="IVD26_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP6078651.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="IVD26_000652"
     CDS             complement(34286..34570)
                     /locus_tag="IVD26_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP6078652.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="IVD26_000653"
     CDS             complement(34560..35294)
                     /locus_tag="IVD26_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAP6078653.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="IVD26_000654"
     CDS             35423..36046
                     /locus_tag="IVD26_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAP6078654.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="IVD26_000655"
     CDS             36238..37359
                     /locus_tag="IVD26_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAP6078655.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="IVD26_000656"
     CDS             37366..40494
                     /locus_tag="IVD26_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAP6078656.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="IVD26_000657"
     CDS             40513..43707
                     /locus_tag="IVD26_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP6078657.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="IVD26_000658"
     CDS             complement(43853..44560)
                     /locus_tag="IVD26_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP6078658.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            45325..45723
                     /gene="spxA"
                     /locus_tag="IVD26_000659"
     CDS             45325..45723
                     /gene="spxA"
                     /locus_tag="IVD26_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAP6078659.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT        14731 a         8082 c         9559 g        13378 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaaggcaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgag aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaatta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgattgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgctc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggt
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagcc agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ctatttcctt gacagaataa ggtttttata
    44701 tttcagtttt tttcactaaa aatcgtgaaa cacgtcaata agtttgatga acaaattaat
    44761 cattatggta gaagtcgatt gatttatttt aatgcaatct ctgtggaatt ttcgaaagat
    44821 ttattttttt aatacagtct caatataact attcaaacat aaaataacgt tatttgattt
    44881 atttgtttat agtaaatttt atttagtaat cattgcttta aaatactacg cttatataac
    44941 agagaaaata agcgttataa taaagaacag tattatttaa aatgacagaa aacattacta
    45001 ttaaagaaat aaaaaacata aaaaatctta agaaatcggt ttcatttagc ttttgagata
    45061 aaataatagt acagttttat acgctgtttc atatgtttag aaaatttgaa ttagatttga
    45121 aaactctaat ttttaaatga taaaaaaagc gagaatgctg gttttactgt atattaacct
    45181 tagataactt tcattttttt aaaaaaatta tgaaaaaaag gtagctattt aaaagttgat
    45241 tatgtataat agaaacagat gggagattat tatgatcttc tgttacaaaa aagtgattct
    45301 tatcacgaaa aggagtggtg cacgttgtta acattatata cttccccaag ttgtacttcc
    45361 tgcagaaagg ctcgtgcgtg gttgcaagaa catcagattc catttgttga acgtaatatt
    45421 ttttcagaac cattgaacag ttctgaatta aaagcgattt tacaaatgac agaagacgga
    45481 acagaagaaa tcatctcgac acgttccaaa gtattccaaa aactgaacat ggatttagat
    45541 gatctgccgt tacaagaatt attggaactt gtgcaaaaca atcctggatt gcttcgccgt
    45601 ccaatcatga ttgatgataa acgtctgcaa gttggtttta atgaagatga aattcgtcgg
    45661 ttcctaccgc gcgatgtacg acaattagaa ttacgtcaag cacaattgat ggctggatta
    45721 tagaaggata atacgaaact tggaaaagac
//
LOCUS       DACBYO010000012        45734 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.012, whole genome shotgun sequence.
ACCESSION   DACBYO010000012 DACBYO010000000
VERSION     DACBYO010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.012"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(230..1930)
                     /locus_tag="IVD26_000660"
     CDS             complement(230..1930)
                     /locus_tag="IVD26_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078660.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            2437..3597
                     /locus_tag="IVD26_000661"
     CDS             2437..3597
                     /locus_tag="IVD26_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP6078661.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            3613..4056
                     /locus_tag="IVD26_000662"
     CDS             3613..4056
                     /locus_tag="IVD26_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6078662.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(4539..5069)
                     /locus_tag="IVD26_000663"
     CDS             complement(4539..5069)
                     /locus_tag="IVD26_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAP6078663.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            5174..5725
                     /locus_tag="IVD26_000664"
     CDS             5174..5725
                     /locus_tag="IVD26_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP6078664.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(5878..6351)
                     /locus_tag="IVD26_000665"
     CDS             complement(5878..6351)
                     /locus_tag="IVD26_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP6078665.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            6489..7961
                     /locus_tag="IVD26_000666"
     CDS             6489..7961
                     /locus_tag="IVD26_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP6078666.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            7958..8668
                     /locus_tag="IVD26_000667"
     CDS             7958..8668
                     /locus_tag="IVD26_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAP6078667.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            9020..9304
                     /locus_tag="IVD26_000668"
     CDS             9020..9304
                     /locus_tag="IVD26_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAP6078668.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(9621..10004)
                     /locus_tag="IVD26_000669"
     CDS             complement(9621..10004)
                     /locus_tag="IVD26_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAP6078669.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(10006..10590)
                     /locus_tag="IVD26_000670"
     CDS             complement(10006..10590)
                     /locus_tag="IVD26_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAP6078670.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(10637..12112)
                     /locus_tag="IVD26_000671"
     CDS             complement(10637..12112)
                     /locus_tag="IVD26_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAP6078671.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            12293..12604
                     /locus_tag="IVD26_000672"
     CDS             12293..12604
                     /locus_tag="IVD26_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078672.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(12719..15055)
                     /locus_tag="IVD26_000673"
     CDS             complement(12719..15055)
                     /locus_tag="IVD26_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6078673.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            15197..15865
                     /locus_tag="IVD26_000674"
     CDS             15197..15865
                     /locus_tag="IVD26_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6078674.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            15868..16911
                     /locus_tag="IVD26_000675"
     CDS             15868..16911
                     /locus_tag="IVD26_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6078675.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(17148..18029)
                     /locus_tag="IVD26_000676"
     CDS             complement(17148..18029)
                     /locus_tag="IVD26_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6078676.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            18188..18916
                     /locus_tag="IVD26_000677"
     CDS             18188..18916
                     /locus_tag="IVD26_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAP6078677.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            19072..19389
                     /locus_tag="IVD26_000678"
     CDS             19072..19389
                     /locus_tag="IVD26_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP6078678.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            19382..19990
                     /locus_tag="IVD26_000679"
     CDS             19382..19990
                     /locus_tag="IVD26_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAP6078679.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            20006..20836
                     /locus_tag="IVD26_000680"
     CDS             20006..20836
                     /locus_tag="IVD26_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAP6078680.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            20974..21462
                     /locus_tag="IVD26_000681"
     CDS             20974..21462
                     /locus_tag="IVD26_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAP6078681.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            21513..22385
                     /locus_tag="IVD26_000682"
     CDS             21513..22385
                     /locus_tag="IVD26_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAP6078682.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            22561..22923
                     /locus_tag="IVD26_000683"
     CDS             22561..22923
                     /locus_tag="IVD26_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP6078683.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            22932..23684
                     /locus_tag="IVD26_000684"
     CDS             22932..23684
                     /locus_tag="IVD26_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6078684.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            23698..25500
                     /locus_tag="IVD26_000685"
     CDS             23698..25500
                     /locus_tag="IVD26_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6078685.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            25777..26817
                     /locus_tag="IVD26_000686"
     CDS             25777..26817
                     /locus_tag="IVD26_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP6078686.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(26869..29013)
                     /locus_tag="IVD26_000687"
     CDS             complement(26869..29013)
                     /locus_tag="IVD26_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP6078687.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(29370..30743)
                     /locus_tag="IVD26_000688"
     CDS             complement(29370..30743)
                     /locus_tag="IVD26_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6078688.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(30743..31138)
                     /gene="rbsD"
                     /locus_tag="IVD26_000689"
     CDS             complement(30743..31138)
                     /gene="rbsD"
                     /locus_tag="IVD26_000689"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAP6078689.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(31166..32083)
                     /gene="rbsK"
                     /locus_tag="IVD26_000690"
     CDS             complement(31166..32083)
                     /gene="rbsK"
                     /locus_tag="IVD26_000690"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAP6078690.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(32191..33204)
                     /locus_tag="IVD26_000691"
     CDS             complement(32191..33204)
                     /locus_tag="IVD26_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6078691.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(33285..33884)
                     /locus_tag="IVD26_000692"
     CDS             complement(33285..33884)
                     /locus_tag="IVD26_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP6078692.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            34070..34771
                     /locus_tag="IVD26_000693"
     CDS             34070..34771
                     /locus_tag="IVD26_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6078693.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            34781..37492
                     /locus_tag="IVD26_000694"
     CDS             34781..37492
                     /locus_tag="IVD26_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP6078694.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            37943..39571
                     /gene="treC"
                     /locus_tag="IVD26_000695"
     CDS             37943..39571
                     /gene="treC"
                     /locus_tag="IVD26_000695"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAP6078695.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(39631..40812)
                     /locus_tag="IVD26_000696"
     CDS             complement(39631..40812)
                     /locus_tag="IVD26_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP6078696.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            41064..42587
                     /locus_tag="IVD26_000697"
     CDS             41064..42587
                     /locus_tag="IVD26_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAP6078697.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(42656..43384)
                     /locus_tag="IVD26_000698"
     CDS             complement(42656..43384)
                     /locus_tag="IVD26_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6078698.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(43397..44677)
                     /locus_tag="IVD26_000699"
     CDS             complement(43397..44677)
                     /locus_tag="IVD26_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP6078699.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(44818..45420)
                     /locus_tag="IVD26_000700"
     CDS             complement(44818..45420)
                     /locus_tag="IVD26_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAP6078700.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
BASE COUNT        14643 a         8159 c         9144 g        13788 t
ORIGIN      
        1 aatacaagaa aaggtatttg gtcagtctcc aaaagtcata ttcttcatcg atcattaaca
       61 gacaaagaac tggcccgcca aggatatgag gacatctcct tgaagtacca gttcgtacac
      121 tcaacttatt gaaccgccgt atacgggtcc gtacgtacgg tggtgtgaga ggggcggaag
      181 gtcagttggc tttcccctct actcgatcgg atgtatttat cccttttgcc taagcacgta
      241 aaagcttgta tctatgataa ataaataaac atagcaaggt aaaccagcca atcaaagtaa
      301 gagaaagaat gaaatagaaa tagattggcg tttgataatg aagcgtgagc tcgttgattc
      361 ctttttgctg cttcacgatt ggggtcccga tatctgttac ttcataatca gtcaatgttt
      421 ttccattttg ctgtagcaca gtccgatcgt agacgataac agggatatga acagttttgt
      481 ccccagtgtt tttccacttg attgtcaaaa gaccgcctgg atgtgttttt ataaaagttg
      541 tttcgttttc tagtatttct tcgttatacc ggtcgtattt attgtctttt gtctccttat
      601 agattggcag atagtcaggt gtggtttttt ggaaaacgaa caagctggta gacatatctt
      661 tgctgaagaa tgttttcctt gcttcttccg gcgtatcgaa tagataagta tgtcgactga
      721 caaatgtttc attttcccac ttttccagat gctggtataa gttctggatc gtctgtgctg
      781 aaaaaataag aatgccaaat atacttaaaa gacggaacca cttttgttca gaccactggt
      841 tcagtgaaag ggcaaggtaa agtagaagca atagcgtaaa tggcacgaaa aatcgaaatg
      901 gaaactggat caaactaata aaaggcacat ttttttcgat caatgtcgtc catggaatca
      961 agctagtaga aagaaaaaag aaaacaagac ttgtgtacaa cacgattttt tggaataagg
     1021 tgttcttttg ttgaaagaaa ataaaaagca aaaaacctga taatatcaat ataggaaagg
     1081 ccttagggta atggagccaa taactgccat ccagatctat cgccttttga ctcatttctc
     1141 tgttaacaaa gggaggaaga atcttattcc cactgtaaac aatagctaat cctgcccaaa
     1201 tatttgctgt cagaacaaaa taaagcaaga ccgacttaat cagttgaagc agtgcttttc
     1261 ctttttcagt ctggttaaaa aagtaataaa gataaaaagg gatatacatc aaagctaaca
     1321 tgatcgaaga cagtaaatgg atctgtgtca taagtcccac tgagacagcg actttgataa
     1381 cagggaactt tttatgaagg acgaaatcag caatagggat catacataaa ggataaaaac
     1441 aagtccccca gctagtgaat ccttggttga tagaccagta ttgaatagaa tacgtactca
     1501 tgaataaaac ggctactggt acacttaccc aatttcgaac attgacatat ctcagtaaaa
     1561 tcagcataga aaatcctgaa ataagataaa gaatgaaatt tgaaagaatc tgataatgaa
     1621 accagctacc tgcaagcaac acgatcaatc cttgtaaata agcgaaaaat gggccgtaaa
     1681 cggcattcac gatcctgcca ctttgctgga atccataaag ggaaggaaaa taatggaaat
     1741 ccccatattt aatttgttgc gcggcatcat agaaccgatt gtaatggaat ggggcatcag
     1801 cacccaaaat tagtttatgt gtgaataaat gaggcatgag aaatgccaaa gcaatgaaaa
     1861 aaattgctaa aaatgggcca tattttttca attgtcgaac tcctttgcaa actttagata
     1921 aattcatcat atatcctatg cgagaggtag gcaagaaatt agaaaattca tgaaaatatt
     1981 tatgaatttt acaagaaaaa cataagtgaa agttctaagg agagaggatg cgacataagt
     2041 tttgttgcat ctccttgttt tgaaacagaa tttttcttaa tactcgaaac aaagtagctt
     2101 tttcatgacc tctcggtaaa cggtgttcaa tcagctgctt ctcggtaata agctcactag
     2161 cctagaaaat atgagaagct attttctgac tagcgctctt attactcaaa gcataacgca
     2221 gttttcacaa cctcttcctt aaacggtgtt caaaagcttg catctgcggt aataagccca
     2281 acccaacaaa aaatatgagt agctattttt ttgggctgta cttattactt gatgcaggac
     2341 agctttttca caacctcatc ggctttcatt ttctattttt ttcctgaacc catataataa
     2401 aagaaagaac aaaaaaactt gcaagggagg acacatgtga agcagagtaa gcaaaaacag
     2461 tctcgtcgac ttttgtttcg tttgttttta ttaatatgta tcgtcgtagg gttactgatc
     2521 gctttatatc cattttatgt ggattcttta aatagtttta ttgatcaaaa acgtatcgaa
     2581 caagtacaaa aacggaccgc agctgaaatt gaagtgcagc gaaagaaaat ggaggagaaa
     2641 aaccaacgat taactgacca aggattcaat cctggtactg atcctttcaa tgaaaagaac
     2701 agaaatgaaa gtacaacatc cagccaatta gaggaatggc tgatcggaag tatcaatata
     2761 cctaagatcc aattaaatat ttcactttat gatcggctca atggtaggat ccttgaaaat
     2821 ggagcaggcg tcttgcaagg aacctctttc ccgcttggtg gaaattcgac gcattcagtg
     2881 atctctgctc acagcggttt acctaatcga cggttattta ccgaattaga tcgtttagaa
     2941 aacggagaca cgtttatttt gactgttttg ggggagaaat tggcttatca agttaaaaat
     3001 atacaagtgg tactgccaga tgacacgtct gttctaacga tttcagaagg agaagactta
     3061 gttaccttgc ttacatgtac gccgtatatg atcaacacgc atcgtttgct agtgacagga
     3121 catcggattc cttataacga atcggtaaaa aaagaagaag gaaaaggaaa tcaggaaaga
     3181 accatgcggc aatggtttat tcttgcagga acgataatag ctgtagtcat actgttagtg
     3241 tttatcggac gactaatcta tcagtataga ttaagtaaaa aagtgcttga tttttcattt
     3301 attattagtg attcgtcagg gaaaccggta aatggtagtt cattcatttt gaaacataag
     3361 aaaaaaacac ttactagaaa tggtgtgccg ttttcagtac aaagcgacca tcatgggaaa
     3421 gtcaagctgg atcaattgcc tggtggaact tatcgaatcg tttcagctga tgatcctaaa
     3481 gttgctgttt cttttggtat tagaaaagta aaacaagaga agatatactt ttttgagggg
     3541 cgaaaacttg taaaagagct tcaaaaaaat ggtttttatt ttaaaatcaa tgaataagta
     3601 aggagagaaa aaatgatccg cacaacaaca aaattgtctg ccaaagaact ggaatctgtt
     3661 ctatcgattt ggctgcatgc taacttggat tctcatgaat tcattccatc aacttattgg
     3721 gagaatcaag tagaatctgt taggaaagct ttaccagatg cagtgattta cttagcagaa
     3781 atagatcaag aaattattgg ttttgctggg gtgattgatc agtttatcgc aggaatcttt
     3841 gtgaaaaggg aataccggca acaaagaatc ggtacgcaac taatgaaaaa aataaaagaa
     3901 accaataaaa cactgacttt gacagtctat caaaaaaatc aatcagctat tcatttctat
     3961 ctttcacaag gttttacaat tcaaacacag caaaaagatg aagcagtaaa tgaggaggaa
     4021 cttgtgatga aatggaatca aaacgctgat ttttgatgaa cagaataacg aaataatgct
     4081 cccagcctaa ttttttgctg ggagcattat ttcattttga agtcactaat ttaactgtgt
     4141 gaatatgcag ttgttacaat ctttgataaa cggtgttcaa tcagctgacc ctcggtatta
     4201 gctcaaaaaa cggcaaaata tgaggaacta tttttccatt tgtttctcta atactcaggt
     4261 caaaacgctg atttcacaac ctcttgataa acggtgttca aacggctgct tctcggtaat
     4321 aagcccacta gcctagaaaa tatgaaaagc tattttctaa ctagcgttct tattactcaa
     4381 agcataacgc tgatttcaca acctcttgat aaacggtgtt caatcagctg accctcggta
     4441 ttagctcaaa aaacggcaaa acatgaggaa ctatttttcc gtttctttct ctaatactca
     4501 ggtcagaacg ctgatttcac aacctctctt tcacaacctt attttactcg tttataattt
     4561 tcatcgaagt attttccgct acggatatca tctggcattc catcgtatgg ttcttcgcta
     4621 ataacatctt cattgtctat acctgcatca cccatataag tgatcgtagc aaattcagga
     4681 acaagtaatt ttggataagt ttcatatttt tcacgagctg cttccatttc tgcgatatgt
     4741 tcgttttgga aagtaacagt gatttctgga tgttcttcaa cccatttagg gaaaaagatc
     4801 attccgtgaa gtttcttttc atttggcata aagtccaatg ccacgtctgt ccctgttggc
     4861 tctgtccaag tgattttgaa tacgccgtcc gtcaatttaa cgatatcagc ttcttggtct
     4921 tttacccaac ggcctttgac cattccgcca tggatacggt aatcaacagt atggtcattt
     4981 ttggcatacc attcatattc ccaaccattg tcatacgtat agataaagtg agttccaata
     5041 aaatcttcca attctttaaa ttctttcatg tttaagcatc tccttataaa ttaaaacatg
     5101 taataaacta catgttttcg attactcatt tatgatagaa tggatttaaa gatttgtcaa
     5161 ggagggaaaa ctgatggcaa gaaaaaatac acttcgatat attttgttag ggttattaag
     5221 taagaagaag atgacaggat atgaattgaa tcaatcgttc aaaaatgaaa taggagaatt
     5281 ttggcaagca aaacatagtc agatttatcc tgaacttgca aaaatggaag agcaaggaat
     5341 cattcagcat caagtagaga tcacaggtga aaaattggaa aagaaagttt atgaattaac
     5401 agaagaaggg aaggaacaat tggcagagtg gattcataca cccaccaatg aactaccggt
     5461 taatcgagac gaatttgttc tgaaattgta tttcgtcaaa gacgtgaatg atccggcatt
     5521 agtagaaatt attcagcagc agcgtgacct tcatgaagaa aaacgacttc atctattaga
     5581 gcgaaaaaaa acgatctttc ctactgaaaa agaaaaacat gaaaattacg gacactacct
     5641 gattttagcg catgcgatca atcgggaaac agaatatgca aattggctaa cagatgtatt
     5701 agaagaaagt aaccgaaaaa aataaaaaaa tatccgaaca gtgatggaga attcctttct
     5761 atatgaaaga aacgcagatc accgttcgga tattcttatg ttcaaacagg ccttttttca
     5821 agtatttatg tagcatctac ttattaaaaa gcttggtact taggagatta gtggcgttta
     5881 gagttctttt aacaactgtt cgtagtcagc tttttcatcg acaggaagga gcttgtaagt
     5941 taattcgtct gtctcgttgt catgaatgat gtacatctta gcattctctt ctttgaagtt
     6001 accgatttgt aaaatcgtat agcgttcgtc gatcaattcg atatctttga ttgcttttga
     6061 aaaaacttta cggacatggt gcattttctt ttggcggatt tctgcctttt ctgcagcttt
     6121 tgacaaagta aatccgtcat ctaaatattt tttgatcagt tctactttta tgactgtagg
     6181 taaacgatat tttctaggac aattcgcatc agcttcgatc gaacgaatga atcccttttg
     6241 ttcccaatac cttaattgac gtggagacac acctacgata tcacttaatt cactgatgcc
     6301 aacaaccaat tgatcatttt ccaacaaacg tttaagggaa gccccaacca tttttgtcac
     6361 tccttttgtc ctcttgcttc ccttaattat atccgtatta acttatgtgt caagtaggtt
     6421 gacaaatagc gaatttagga ctaaagtatt ctagtagttt cagaaaaaat tcagaaagaa
     6481 ggagaaatat gagtaacaac caacccgtag atatttacgg aaaaccatat aatcggacac
     6541 ttttagttgt tgtcttatta attggtacat tttgtaccgt tttgaatcag accttattga
     6601 cgacagcttt tcctacattg atgaaagctt tcgatatttc agcgtctgat gtgcaatggt
     6661 taacgactgg tttcttgcta gtcaacggga tcatgatccc aataacagca tggctgatca
     6721 ataaattcag ttcaagaaat ttatatcttt ctgccatgac gatctttttg atcggaacga
     6781 ttacttgctt tacagcacct aattttagta cattactaat cggtcgtttg atccaagctt
     6841 gcggtgtggg agtatcgatg ccattattgc aaaatatcat gctatctatt ttcccgccag
     6901 aaaaaagagg atcagcaatg gggatgtcag ggatcgttat tggacttgct cctgctttag
     6961 gccctacatt atctggttat atcattgata actaccattg gcgtgacttg tttggtatgg
     7021 tactgccaat cgttgttctt gtcttggttt tagcattctt cctaatgaaa agtgttattc
     7081 cattgtcaaa tcctagcatt gatattttat ccgctatttt atcaacgatt ggattcggta
     7141 gtttacttta cggattttct agtgtaggag atgacggctg gggaagcttg aaagtaattg
     7201 gtttcttagt tgttggtgtg attttcatcg ccttgttctc atggcgtcaa ttacatttgg
     7261 aacatccatt cttggaactt cgtgtattca aatcatctac attcacgatt gcagctgttt
     7321 tagctggtgt aacaaatatg gcgatggtag gggcagaaat ggtcgtacca ttgtatattc
     7381 aaaatattcg tggagaatca gcattccatt ctggcttgat gttgttgccg ggtgcattga
     7441 tcatgggggc tatgatgcct gtgacgggtg cgattttcga taaatacggc gcgaaacgtt
     7501 tagccatcac agggatgttc attttgacag cggcaactgc accatttgct ttcttgacaa
     7561 aaacgactcc agttttatat atcgtgatcc tttatgcgat ccgtatgttt gggatctcca
     7621 tggtcatgat gccggtaacg acttctggta tgaatgcatt gccaaataac ttgatcagtc
     7681 atgggacagc ggtaaataat acattccgtc aaatcgcaag ctcgattggt acagctattt
     7741 tgatcagtgt gttgacgaat gtgacaaaag caaatatccc aagcaaatct gtattggata
     7801 atacgccatt agcttataaa gatcaggcaa tcaatgccac actgtcaggt taccatgccg
     7861 cgtttatcgt agcgatcatc tttgggattc ttggctttat tattgccttt ttattgaaga
     7921 aaaaagaacc tgttctaatg aaagcggggg ataatgcatg attattggag ttttgattgt
     7981 cagcttgctt gcttttgctt taacgaacgt gttcgctaaa aaaacatggc aaaccttttt
     8041 atctttgatt ttcggactaa tcttcgtcgc ttcactaagt ttgatcgtcg ctaatttgtc
     8101 caatcacttt ggaatggaaa aagtaacgga aacaaaaaca gaaaaaattg tttccagtgc
     8161 tgattcccaa ggagcagata tgcttttgta taaagcttta gggaatggaa aagaaaaagt
     8221 gtatctttac cgaacaaatg aaaaacaaga aaaaccaaaa gcaactggta cggataacga
     8281 aacaaataaa gtagaaaaga cagacggcga tgctgaaaaa gtgacgaaaa ctacttattg
     8341 ggaatacaaa aacgacatgt ataaattctg gttcaatatt gctgataaca atcacgaata
     8401 tgacagccga gtgaatacat tcaaaatccc agagacatgg gtagaattaa gtacggacca
     8461 agcagccaag ttagctgaat tagtgaagaa acagcaaagt acgatggaaa gtgaagcaaa
     8521 agcttatgtt caagacggta tggtaaaagc aatgactgaa aatccaaaaa tgagcaaagc
     8581 agagcaagaa caacgtacga aagccttagc tgctgaattc caacaacaag cattcgcaaa
     8641 attagtgaaa gaagcaaaag gcgaataata ttttgaacac catgtaggag gttgtgaaaa
     8701 agctgctctg catcaagcag taagaacaat cagataaaaa tagcactcca tatttttcat
     8761 ctgattgggc ttagtgccgt agatgcaagc ttttgaacac cgtttaagga agaggttgtg
     8821 agcctgccgt ttaactctga gtcacaagga gcaatttcaa aaaacagctt ctcatgtttg
     8881 ttgactattg tgacttgtga ccgaggagtt ggcaggagaa caccgtttat tcgaaaaaag
     8941 gaactgcgac aagacttttg tcacagttcc ttcttttttt tgctatgcta tactagatgt
     9001 aaaaaatagg agaaataaaa tgagggaaat ttattctttt gaatcaaaaa tctatgcttc
     9061 cgaagtcggc aagggcgggg catatattat ttttccgtat gatataagaa aagaattcgg
     9121 tgctggaaga gttaaagtcc aagcaacttt tgacaatgtg ccgtatgaag gcagtatcgt
     9181 gaatatgggc gtgaaaaatc cagatggttc agtctgctac atccttggac tacgaaaaga
     9241 tattcgtaaa aacatcggaa aagaaatcgg tgatattgta gcagttacag tgaagcaaaa
     9301 ataaaagagg ttgtgacaaa agacgtgtca caacctcttg ataaacggtg ttcaaaagcc
     9361 agtttctcgg tagtaagtca aatttatgca aaaatgtgga aacccatgtt tacaaaattt
     9421 ttcttactac tcgaaacgaa gcggctttat cacaacctct tgataaacgg cgttcaatca
     9481 gctgtccctc ggtattagct caaaaacggc aaaatatgag aagctatttt tccatttttt
     9541 tctctcatac tcaggtcata acgctgattt cacaacctct tctttcataa tggtttttca
     9601 ccatctttat aataaactgg ttatttgata tggaaatcta ttttttccaa ccaatctaaa
     9661 atcttgtaac ctaactcttc tgacatcgga aaagaggcgt tgatttgtgc attggagata
     9721 tggtcaacat ggataccgga agtgatcgta caacttcccg gaacggcagt tttgatgatc
     9781 acagctattt tttcggctaa gacatcgtct ttatggaacc gaccatcgtg gctagggaaa
     9841 cgtacagttt gcatctctgt atcacgagaa aatgtagtga ctgttccgat atgtggtgta
     9901 tctccgcctg ttaaagtgat caataagtct ttaccgatta ctttaacagc agcttggatc
     9961 gtgaaaccta gtttggttac ttcaactatc gtttcttttt ccatattaat caccctgcca
    10021 acgttttgaa tgctcattta caatttcaaa ttgatccaaa agtttcattg tatggtgatt
    10081 aacaagatct tggatcgttt gaggctgatt ataaaaagca ggaattggtg gtatgatttg
    10141 cacacctagt cgtgctaatt tagtcaagtt ttccaagtga atggcattta atggcgtttc
    10201 acgaggaaca atgactaact ttcgttgctc cttcattgtt acatcagcag cacgtgcaat
    10261 caggttgtcg cctaaaccaa cagagatacc tgcgactgtt ttcatacttg ccggtacgat
    10321 gatcattcca tcggtcaaaa atgatccgct ggcgacagca gcacctaaat ctttgtttga
    10381 ataatggtaa tcaaacaggc tttcgaattc agttagtgat aagtcggatt ccagctttaa
    10441 gttctgtttt gcccatggac tgatgattcc gtgtgtttct atcatcggat attcttttag
    10501 tttcttcact aggttgatgg cataaatggt gcctgaagcg ccacttacac caatcacgat
    10561 ttttttcttc cgttgtgcca attgttccat tttccgcact cctttttatg atgtcaaaac
    10621 agttgcagat cattcattat ttcaaatatt tttcccaatc ttctacttct tggaattttg
    10681 cacgtacaaa atgttctttc atatcgaaag gaactgtacc gtcaaagata gtttttgcac
    10741 ttatcccacg gaaacgaata gagccaggat tatattctgg taattctgat gggtccaatg
    10801 gatggttcct cattcctggg atcacgatga tatctttatc tccttggaaa cgagtgttga
    10861 aagtccaaac tacatcgttc atgtcgaaaa tatcaacatc ttcatcgact aaaatgactg
    10921 tcttcaattc tttgaaggct gataaagcaa gaatagctgc ttgacgctga ataccttcat
    10981 ccgcttcgtt ttctttacgg atttgcatga tggtcatcaa tttaccacca cctgcaggag
    11041 gattgtagac atttactact tttcctggaa tagctttatc gaccaaggca agaatacttg
    11101 cttctgtagg aataccggcc atagatacgt gttcttcact gggaccaatc gttgtttgca
    11161 tgattggatt gtcttttcgg tgagtaactg ctttgacttt cactacttgt acagctggat
    11221 tagcatcccc agtatagcca ggaaattctg gcattgcttt tcctgagttc gtgttgatat
    11281 cttcttgcat tgtttcattt ggcatgattt ctgcttcaat gatgaattca gcacgagcaa
    11341 tacccacttc atcgactgct ataccatcaa cgatttgaat aggttcgtta cgcaaagctc
    11401 ctgcacacca tagttcattg tagccaagtg gagtggtagg tggttcgaaa gtcgtgccaa
    11461 tggcaattgc tggatctaaa ccaatattga tagtgatagg cattggttta ttcaaggctt
    11521 cgaattgttt ttggaagtga ccaatgtggc gtccgccagg catgatgtac ataccgatcg
    11581 tatctttatc ttctagaacc atacgatgga tcgttacatc gctcattgtt ttttctggat
    11641 ctgatcctaa gactacaccc attgtgatgt atggaccagc atcttcagga gtatttgtag
    11701 gtgcaggcaa aatgttgcga atatcgaagt ctgcatcggt agctagatga acgacttctt
    11761 gtgctggagc gtctgctttg tctactttca caggtttgat tggattttct acagcgtctt
    11821 tcaagaaacg accaagtgtt cgataatcat ggtgcaaaat ttcacctaca cgtttacgac
    11881 tagccattgt tccgatgttc acacgtgtgc cggggaaacc tttgatattg ttgaaagtca
    11941 tagctggtcc ttcttgagtc ggacgtttta ctgtaccgcc agcaccgata taacggtaaa
    12001 caccagataa ttctgcttca ggatcgattt caatatctgt ttcgtgatat tgacctggaa
    12061 gtgtttttag ttcttcgatg acttttctta aatcatacgg ttgatctgtc atgagagatt
    12121 cctccttagt tgtctttacc tatctatagt aaaaggtgaa aaagaggaaa acaattcaac
    12181 ttgttcggta aagtattcta caatggaatg gatgcgtttt tttgataata gaataaacta
    12241 tgatatactt atcactaaaa gaaagcgcat acttagtgtt ggaggaagga aagtgaaaaa
    12301 aatggaggag tcatttccta aagcagtaaa agtggaaaat atagcgaata ttttgaaagt
    12361 tacatttgaa aacggagaag taaaatacgt gaaatctcat tggacagaag agataaccga
    12421 tgccttgcaa tttggaaaaa aaggaagagg aaaaagaaaa aatcttctcg cactttctcg
    12481 taatatgtgg attgggactg aagtaacgat tgaagcagat ggaacagtat tcataaatgg
    12541 aaaagacagg tatacgccag aagagttgtg gtacaaagga aagaaaagta taccagaatt
    12601 ataaaaaata attaaaaaaa acagcgcgaa acaaggaaca tattacttcc tcgtttcttg
    12661 ctgttttcta ctatttcagc gctcttatga ctcaaatcta aatgtggttg tcacaacctt
    12721 attctgcacg caaagcgata gcggcgtctt ttttcgctgc cattcgtgca ggaagatgac
    12781 cgccaagcat cgtcaatata gtagagacga tcactagaat aatcgcatgg acaggattta
    12841 gttgagcaac attttttaga tccgtcatgt tgtataagat gctattgata gggaacgtag
    12901 ctagccatgc aataaacaca cctaatatcc cagaagaaat acctaaaata cacgtttctg
    12961 cgtcaaatac gcgagtgatg tcttttttac gtgcacctaa agcttttagt acaccgattt
    13021 cttttgtccg ttcaatcaca gatgtataag taatgatact gatcatgatc atacttgtta
    13081 ctaaagagat ccctgcaaaa gcaataagga cataagtgat agcatccatc aatccgccag
    13141 tcagttcagt catcgttcca gctaaatcag tataaatgat tttatcttca tctgatttgc
    13201 ctttattgta atcatctaga taatccaaga tcttttcttt gtcttcaaaa ttgttcggat
    13261 aaatcatgat acttgaaggc aagctgtctc cacctaaata actaagcaat gtttgtttgg
    13321 cattttcgtc aactttttca gtagttaaga catttacacc actgtctctt tgagctttga
    13381 cgatttctga ttctttgttt tcgttgacga tttgagtcgt taattgatcg ctataagcga
    13441 ttcctggaga taagagattc attgtagaag aagatttcac gcgtaggatc cccgagatct
    13501 tcaattcatc agaagcattc tgatacatcg catcataatc tgtattaggg ataaaattcc
    13561 cagttggaag ttttgtatag taagtattgt tgtttactaa tttgaatgtt gtaccaacga
    13621 tatcatcaaa atcaagtttt tcgtcttctt tcacatcaaa tccaagattc ttcaatgcgt
    13681 tgatattagt attattattg ccgtctacga tcagcacgac atctgttgct gaggctggat
    13741 aacttccggc aagtaaagaa taattgtctt ttaaaaagtt ttctttgcta gtgtcaagct
    13801 gtgtagggaa acttgacact cccacacctg tcattgctga catcgtacta gataaagaaa
    13861 gagattccgt atcaggattt tgattcgaga agctgacagg ctgtactttg ccatttacat
    13921 cacgtaaaag attgattcct gtagtacggg taaatccgat attattactt aagttaggat
    13981 cgatgtctgt tacgtaatcg acgtatgttt gatcaatctt attcgtgtgc tgtgctttat
    14041 cttcttcgct gacttttgca gtaatcgttt tgctgtctgg ataatccgct ttgcttgcac
    14101 ccaatccggc atcgtcacga gtctggttag tcgttacctt agaaatagta atcggaaatt
    14161 tcgccatcgt ttcagcttgc gtgttatcga tttgtttttg gaatccagaa gaaagggaca
    14221 gaacgatcgc gattccgatg atcccaatac tggaagcaaa ggaggtcaag aaagtacgtc
    14281 ctttttttgt tcggatattg ttgaaggaaa gctttaacgc tgtccaaaaa ctcatctttg
    14341 ttctgcgtaa gttaaattga tcatcttttg gtcgttcgat gtgaggatgg gaatctgtta
    14401 agatcttacc atcagaaaat tcaatgattc gatctgcgta ttgatgggcc agttcaggat
    14461 tatgtgtgac catgatcact aatttttctt tcgataactc ttggatcaat tccatgatct
    14521 ggatacttgt ttctgtatct aacgctccgg ttggttcatc gcacaaaagg atatctgggt
    14581 cattggctag tgctcgagcg atggccactc gctgcatttg tccaccagat aactgatttg
    14641 gctttttatg catatgattt gtcaagccga ctcggtgcaa tgcatcttct gcccgttttc
    14701 gtttttcgtc tttagaaaca ccacttaatg tcatcccaag ttcaacgttt tcaataatgc
    14761 ctagatgacc aatcaagttg taactttgaa aaatgaaacc gatagagttg tttcggtagg
    14821 catcccagtc actgtcctta aagtctttag tagactttcc gttgattacc atatcaccgg
    14881 aatcataatt atctagtcca ccaatcacat tcagcatagt cgttttacca gaaccactag
    14941 gacctaaaat cgctacgaat tctttttgtc tgaaagcgac agacacacca tccaatgctt
    15001 tggtggtggt ttcgccgact ttataatatt tttttatatc ttttaattga agcataatca
    15061 cccttctccc gtattgaaat attcggtata ctaataagta tatcagaaca atgatcgtag
    15121 tatacgaaat aaatgttaac tgaagatgaa ctacaagaaa aaatctagaa atttttcaaa
    15181 aaacagaggg agatcaatga atcgtatttt agtagtagaa gatgatccgc aattacagtt
    15241 gctttaccgt tctgtgttgg aacgagcggg cttttcagtc atcaccgcat tgaatggaga
    15301 ggatgcgctg aaaaaactag aagcgacacg tatagaatta atcattacag atatcatgat
    15361 gccgaaaatg gatggctatg acttgctaga ctcattacgt agcaccagat ttgacacacc
    15421 tgttctaatg attacggcaa aggccgattt tgaggataag aaacgcgggt tcaaattagg
    15481 agcagatgat tatatgacaa aacccatcga tgtcaatgag atgatcctac gtgtggaagc
    15541 attgcttcga cgttcaaaga tcaattacag cagtagcttg ataatcggac aaacaaaatt
    15601 agagctagat gcttatacag tgttacaaga tcagcattcg ttgattctgc ctcaaaaaga
    15661 atttctgctt ctgtataaat tactgtctta tcccaacaag atcttcactc gccaacagtt
    15721 gatggatgat atttggggat tagatacgaa tacagaagaa cgaacgatcg atgtacatat
    15781 caaacgttta aggacccgtt ttgaaaagac ggaagatttt caaatcatca cagtacgggg
    15841 actaggctat aaggcggtta tttaaagatg aaaaaaaagc tattttcaca attatggatc
    15901 tattttgcta gtattgtctt catttcgatc ttagtgacac tgctgtgttt tctcggtttt
    15961 attttcttat tgtctcgaca ttctatctcg cctgctgaat cggctggaaa accaacgtta
    16021 tacccgttat tcgtctttgc ggggttcagt atggtcgtgg gtacaggaat atcgattttt
    16081 gttgggcggc gtatcctgca tccaatcagt gcgctaggga caaatatgag tctggtagca
    16141 acgggagatt tttcgattcg aatggatgaa cagcagaaag tagcagaagt acagcaactg
    16201 tataaagatt tcaacgttat ggtccaagaa ctcaatagta tcgagacact gaggaatgac
    16261 tttgtgtcca gtgtatccca tgaattcaaa acaccactag caacaatcca aggatatgtt
    16321 caattgttac aagccccaaa tctctctgac gaagaacgcc aaatattttt atatcggatt
    16381 atcgaaagta tcacgcagct ttcacaatta acagagaaca tcttaaaatt gaacaaactg
    16441 gaaaaccagc gtatccaact ggaaaagaaa gagtatcgat tagatgaaca aatcagagaa
    16501 gtaatcgttt tttttcagcc taaatgggag aaagaacagc tagaattgga tatcgaactt
    16561 gctgcagtaa attacacagg caatgaagag tttttgtacc aagtgtggct gaatatcatg
    16621 gataacgcca taaagtacaa tcaaatcaat ggacagattc atatcaaact atttgagaca
    16681 gccacagaga ttgtactgga agtgaccgat tcaggtgtag gaatgaatga agagaccaga
    16741 gatcgaatgt ttgaaaaatt ttatcaagga gatacaagtc gtcaaatttc tgggaatggg
    16801 ctaggacttt cactggttaa aaaaattcta gaactgcatg atggacgtat tgattatagc
    16861 agtatcgaag gagtaggaac gacagcaatg atacggttaa gtaaacaata ggaaaaagaa
    16921 taaaacccct aaaaattcta ttgaaggttt ttaggggttt ttagtcgttt ttttgtgatt
    16981 agggaaatgt tcttacggtt cttttggcat aaaaatcgct gctttcttat tgaactacga
    17041 gaaatgttag aggtgtcatt gaaacaagga catgatgcaa gaaagagagc gaaagtcatg
    17101 cgtcgctctc tttttttggg tggatagatg gacagaaaat gtagggctta gttttcttct
    17161 tgatttaaat actcccaaaa tgtatctgaa gccaaagaat gctcaccgac tttacgagta
    17221 aatgcaagat aactctctgt tgttggagaa atagggagaa tcacagtatt ttcttttaat
    17281 agattcttga ctgttttttc cataacaata gcaatcccca tgtcatttgc aatcatattg
    17341 atgatcaagt cgattcttgc tcctttataa gagatttttg gttcaaatcc agcttcgcga
    17401 cacagatcta gtacaggttg atacaagttc gtagtggggc caaggagcaa aaagttctcc
    17461 tttttcagtt cgcttagatc caatttcttt ttactagcta aaggatgatt tttaggtaga
    17521 actgctacaa aatcgtctgt ttcagtaggc aaccactcaa tcgaacttgg tggggcctgg
    17581 aaacttctag caaagtggat cgtgtcacta tgttcattgg cgtcattgta agttaattcg
    17641 acactttcca cttctttcaa ctggactgta aattcaggat ggcgtttcaa aaactcggtg
    17701 attttggaaa aacctttata attgatcatt gtcggtatcg ttaagatatt taatgaaaga
    17761 ttgttgtctt tcgtataggt ttcaagcact tcttgcatag catggtattg ttctacgaca
    17821 ttttttacat atgggagcaa taagcttcca gcttcggtca attcgatttt tctatgggcg
    17881 cgttcgaata atttgacgtc taattctgtt tctaacgaaa gaatctgttt agaaatattt
    17941 ccttgggtgg tgaattgtcg atcagcagtt ttggtgaaat tcattgtttc ggctaaatca
    18001 agaaaaactt cgaatttatg gatatccatc atattcctcc tacttattcc aataaagaat
    18061 actttaacac aaaaaatgaa ttggtgtaat cttctctgtc tgttacaatc tttcttgcag
    18121 cgaaagcaat aattacagaa atttttctga tttttttcgc ttcgtagaaa aagagaggag
    18181 ttttttgatg ccaactggag ttttgatcaa tgtaggttcc gttttgtttg gcggactaat
    18241 tggcggatta gtaggaaata aattaagtga acattttaaa gcacagctga cgatggtttt
    18301 tggtgtgtgt tcgatgggga tgggaatcta ttccattgcg ccgatgaaaa atatgccggc
    18361 tgttattttt gctttagtga taggaacagc gattggtttg attgttcatt taggtaatgg
    18421 gataaataag ggggctgcgc tgatgcaagt acctatttct aaaatcttcc ctagtgaaaa
    18481 gcttggtatg acccacgatg aatttatcag cacattagtg acggtcattg ttctattttg
    18541 tgcaagtggt acggggatct atggaagttt agattctggg atgacaggag acagtacgat
    18601 tttgatttct aaatctgtcc ttgatttttt cacagcagct atttttgcgt gtaatttagg
    18661 gtatgtcgtt tctgtgatag caattcccca attcattatt ttttatattt tgttcttatt
    18721 ggcaaaattt atttatccat tgactacacc agacatgatc ttagatttta aagcttgcgg
    18781 cggattcttg atggtcgcta ccggttttag aatgatcaac gtgaaaatgt tcccagtagc
    18841 tgacatgata cctgcaatga tcgttatcat gccactgagc tggatgtgga caaattggat
    18901 tatgccactg ttataataaa aatcaaagag aagccatttt ttgctgacta aaaaggatca
    18961 aatcttttag tcagtttttt tgtatttgac aaactgattt tgaaactata ttatatgttg
    19021 tataatatag attgaaataa aatattacac ttgagaatag aaggtgacgt aatgcacatc
    19081 cagattccaa ctgttcttct tgatggtact gtgctagcag cattaagcaa ggaagatatg
    19141 tatgggtatg ccttaacaaa aatcgtacaa gaaagtctct ctgtcagtga atctacacta
    19201 tatccggttt tgagaagatt gaaaaaagaa ggatatcttg agacctatga tgaacctttt
    19261 gaaggcagaa accgtcgata ttactcgttg acaccaatgg gaagtcgtca tttagaagaa
    19321 attattgatg aatggattgt ttttcgagat tctttagacc ggttattgga ggagagcaca
    19381 aatgaatgaa tatttgaatg aagttgtgga tcatcttcaa gaaattcctg aagacgatcg
    19441 ttttgatttg atccagtatt atgaggaata ttttttagat tctggaaaaa cattagatca
    19501 gatcattgat gaatatggta caccaaagca gtttgcctta aaattaaaaa tcagttactt
    19561 ttcagaagaa gaacaagcag aaaacgagtt agtgaaaaat ccaaaaagac aaattcgcct
    19621 gatttggtta atcattatcg gtttatttgc ttctcctgtc ctcattccac tagcactggg
    19681 gtttatattg gttattgggg gactattggt tgctttacta gcgctcattt ttagtatcta
    19741 tgttttatgt atcagtatct taggtgttgg cctattcatg atcatctcag gaatcagtgt
    19801 gtttggacaa tcgattctga gtggattatt ctttatcggt gtcggtctgt tcgccacagg
    19861 aagcgcagta tttatttcgc cactgttgct gaaaggaaca aaagggcttt tttatgtcat
    19921 gatgaacttt gttaaatgga tgggacgacg ttttattaca aaaagagatc tgcattcagc
    19981 gggcgtttga aggaggacac ataaattgag attgaaacat tttttgatta ccggtattgg
    20041 tctgatgctt actggtggcc tcctagcagg tgcaacttat acattaggcg ctcaaaagag
    20101 tctgacttgg gataatggtc ctcggttgat cgatatggtt actgagacaa aaaaaatcaa
    20161 ggatgcaaac aaaatcgtca tccatgcaga aaatcaaaca gtttcggtca tacgcggatt
    20221 ggattttgag ataaaaacga cttatgataa gacagaaaag ccagaaataa aggagaaaaa
    20281 tggcgtgttg actgtgaatg cagtcaaaaa atcaacaggt gcaatcatta gtttagaaga
    20341 cacaagtgca caaatcacta ttgttgtccc tgcagatcat gaattatctg aattgacaat
    20401 cgaagggaat aatagtgcaa ttgatatcaa cgaagtatca atcaaaaaag tgaatactaa
    20461 gacacatgat ggctgggtat cgttcaatga atttacagga ggaacaataa ctgcgaaaga
    20521 tgaattaggc tcacttcgat tagatgaggc caatgtggat aacttgatcg tcacaggtga
    20581 aaacagcaac ttccatctag aagacagttt gatcagcaaa gaaggaaaag tcatcctaaa
    20641 cggtggcaat ttatctttgc atgagatgga aaacagtggc tatactatcc aaacgtctgg
    20701 tgaatcttat attgaaaaag actaccagcc aataacaaat actttgttag aacaaggaca
    20761 gaaaaagcta aagatcactg ctaaagacac atcgatcaat attacgacgg atcaagagga
    20821 caatgaaaca gattgatcct gtactcaact ggatatttta agaaaaaaca gcaaagatcc
    20881 ttccaatctt tgctgttttt catcgcttaa cgcacataac tatagtaaaa taagaaagaa
    20941 aatatctaaa aagaaaacag ggtgaaagag tatatgaagg tagaagaagg tcaaagagaa
    21001 aagttaaaaa cagaaatgga aagattacat acttatatca ctcaactaag ccaaaccttc
    21061 tatgatccag acaaagaaaa agtgatggtt aattacccga acaattcaga aggtcgccaa
    21121 ttagagcaag tgtaccatga agttttcaaa catttattga cggtgaagaa agagctggat
    21181 tattattctt taccgattat cgatacagga atattgaagt atgatgggaa gaaggaacga
    21241 tttatcttta aatctgttcg ggaagatttg cctctttcag cagggatgga tctagaggtc
    21301 ttggtagaag actattttac agaagaaaag cactgggttc gaacaaaatt ggattattta
    21361 ccgcaggcag ccggagggac acaggcaagc ggttggtaca tcactgaaga caaagagtta
    21421 gaactagaag gtgtaatggc gcgtattcga aaaaaaaatt aaaaaagtaa cattagatat
    21481 ttattgaagg ataaaggagc gcaggaagta gcatgagaga aaaaagagca ttttatatca
    21541 atggttatgc agggattgtc ggattggtcg tattagcttt agttggattg tttttcttct
    21601 atttaggtat gtggcaagcg aaagtttggg cacttttttt aagtattttt ctttggttga
    21661 tcacgttatt gttgttaagt tcggcaactg tagtcagtcc taatcaagca aaagtaattt
    21721 tgttttttgg acaatattta ggtacgattc gagaaaatgg ctttttcctt acgatacctt
    21781 tggcacaaaa aatgactgtt tcgttgaaag ttcggaattt caatagttct gttttaaaag
    21841 tcaatgattt ggatggaaac cccatcgaaa tctcagcagt agtagtcttt aaagtcgttg
    21901 atacagcaaa ggcattattc gatgtagcgt attatcaaga ttttgtagaa atccaaagtg
    21961 agacagccat tcggcatatc gctagccaat acccgtatga tacattcaat gagaatgatt
    22021 tgacgcttcg aggaaacacg acggcagtgt ctgacgagtt gcaaaaagag ctgcaagagc
    22081 gtttagcagt agcaggtgtc gaagtaatcg aaacacgctt gaaccattta gcctatgcaa
    22141 cagaaatcgc tagtgccatg ctccaacgtc aacaagcaaa agccattttg tctgctcgac
    22201 aaaccattgt tgaaggagct gtcacaatca ctcaaatggc cttagagcaa atcgaagatg
    22261 gacaagaaat caatttcacc gatgatcgga aagtccaatt gatcaataat ttacttgtct
    22321 caatcattac agacaaagga acgcaacctg ttatcaatac aggcgacatg aaagaccgta
    22381 agtgacatac tttttgtaag ataggaagaa ggagtttagg acggattatt gtcttgaact
    22441 ctttttttag ttgttttaaa gaaaatgaca aaattgaaag aagaatgata gttgattcga
    22501 aggcagaatt gttcgctttt ttctataatc agtatataaa gtaagagaga aggggaaaaa
    22561 gtgaaaaaac ttctgatcgg tctacttgtt ttcatcgttg tggtacttgc aggggtgaaa
    22621 atcgcagatt acgtagttat gggtggagaa gaatactatg tacaaattac gacagatggt
    22681 acaaaaacag tttcaaaatc agactctgga caagaaacag tcaactatag atatatcctg
    22741 cctggctata cgaaagaggg taaggaaaaa gaactggact tcaagggaca attgactcga
    22801 ccgcttcgta aaggagcata tttaaaaatc acctggaaca aaaataaagg tgtcacttcg
    22861 tatgaagaag tcgaaaaaaa agacgtgccg aaaacagcac tggaaaaact aattaaaggg
    22921 tagggaaaga aatgaacaaa atagtcgaag tacagaatgt aacaaaagta tacggaaaaa
    22981 acaatgagaa aaagacgcaa gcattaagcg gcatcagctt cgatgtagaa aaaggcgaat
    23041 ttattgggat catgggcgct tctggttctg gtaagtcgac acttttgaat attttatcca
    23101 cattagataa accaacagat gggcatatcc gaatcaatca aaaagatgtg accacattaa
    23161 aaggaaatca actagcagat tttcgtgcga atgagattgg ctttattttc caagatttca
    23221 atttattaga aagcttgaca gcacaagaaa atatcgctgt tcctctttct ttacaaggcg
    23281 tcagaccaaa agaaatcaag caacgtgtcc aaaaaattgc agaacgttta tccatctctc
    23341 atattttgga aagctatcct tctgagattt ccggtggaca aaaacaacgg gtcgccgccg
    23401 cacgtgcatt gatcacacaa ccaacgattc tattagggga tgagcctaca ggtgcgctgg
    23461 attccaaaag tgcccgggat cttttagata cgatggacga attgaataca aaagatcatg
    23521 tatcgattct tcttgtgacg catgatccgt tttctgcaag ttattgccaa cgtattttat
    23581 tcatcaagga tggcggtatc catcaagaag tgaaacgtgg agatcaaagc cgtgattcct
    23641 tctatcgaga aatactatct attcttggaa acttggaaca gtagggggag attgactatg
    23701 ctttggaaat tatcacttac tgggatcaag agccgtttaa gagactactt ggtgttattc
    23761 tcaggattag ttatggcatc tgctattttt tacatgtttg aatcaatggc aagcaacgaa
    23821 gcttttttga aaagtaatac gatcgttgcg gctacagtta tcattttccg attcggttct
    23881 gttttactag ggatcatcac attcgtttat attttatatg caaattcctt tttgatgacg
    23941 atgcggcaaa aagactatgc aatgtttatg atgctgggag caaaaggcag aaaaatcgca
    24001 cagatgattt tttctgaaac attcttagta gggatcgcag ctactttagt gggttcagct
    24061 gtcggtgtag gattgacaag tatcgtccac cgattattag tggatcagtt agatctcaat
    24121 atttcgcatt ttacaccttt tagtattcac gggttgttga tcactgtttt gttttttgct
    24181 gttttgtttt tattagctgc tgttgtcaat gctttttcga ttgtcaaaaa accgatttta
    24241 gcattgattc gtgcggatca gacaccaaca agaatcaagc agcataaatt cttgtttttc
    24301 cttgaagtag tactgggaat tgcttttcta ggctgcggtt actatatgat gaaacacgtg
    24361 gggacctatc aagtctttgg tataggggta gccttagtta cgatcgtatt aggaacttat
    24421 ttcattttcc attctgtgat cattttcttt ttatcattac taaagaaatc agaacagatt
    24481 tcattgaaaa aattgaacaa tttcacattg tcacagttaa actttcgtat tcgtgaatat
    24541 acacaaatgc tctcaatggt cgctatgctg tttgccttgg cactgggcgc tttgacggta
    24601 ggattaggtt ttaaaaatga aattgcagac ttgacagaaa acaattctgg atatgatcta
    24661 gtgatgaata atcctcgggc agaagatcag caaaaaatca aagaactttc accaacactt
    24721 tctgcttctt atactcaaaa agaagatgcg ggaacgattt actataatgc aagtgaattt
    24781 gcggctcaac cattgatcat gataaaacat gaagatggaa caccgccgaa gatcacgaaa
    24841 gaaaaagttc ctgctaaaaa aatgaatgaa ctgactgtac aagaggaact tcgaagctat
    24901 gaattgccgg aacagcaaga aaaagaaatc aaggtagtca gtcaatcaga atttgatcaa
    24961 ctgaacttgc cacaatccac tttacagcta gttcaggtaa aagacttcca agcaaacctg
    25021 aaaccaatcg aaacacttgt tgctcaaaat aaaatgaaca atccatcttt gcaaaaagta
    25081 gagtacagca accagaaata tgaaatgtat gaagtgtata atggtctatt ctctggtttt
    25141 gaatttatgg gattcttcct aggtttagct ttcttgacca tgcttgctag ctgtttgatg
    25201 ttcaagatct tgtcaggaag caagagtgac attgctcgtt atgaaatgct tgaaaagata
    25261 ggaacacgac gcgggttgct taaacaatcg atccgtagag aagtaggcgt gttattctta
    25321 gcaccaggaa tcttaggtgt agtccatgtc ttattcggat tacaaatgtt tggtctattc
    25381 atgcaaaatc catacaaaga tatttgggtt ccgtttacga tattcttcgt attgtatttc
    25441 atctactatg tactgacgac atggttatat actggaatcg tattgaaaaa gagattgtga
    25501 aaaagctgtc ctgcatcaag taataagaac agccaagcaa aaatagctcc tcatattttt
    25561 cgtttggttg ggcttattac cgcagatgca agcttttgaa caccgtttgt tcggaaaaag
    25621 aggttgtgac aatatttttg tcacaacctt tttttcacgg tcttttatta gaatatagta
    25681 aattttttct cgttactcac ggaataagct gttaagaaaa cggtttccat gtatactgga
    25741 atcagtgcaa atgaaagaaa agagggtgca aggaacatgg aaatcaatga acaaaatttt
    25801 ggcgaaaact atcacttgat tacgatcacg aatcaaaatg ggacatcttt gtctgtcagt
    25861 gatcttgggg cacgggttgt tcattttcaa acaataatcg ataatgaaaa acgagagttg
    25921 atcttaggtt ttgatgaagc aaaagaatat ctagaaaaag acccttatat cggtgcttca
    25981 atcggacgta tggctggacg gattacgaat ggcacattca aattagatga tgaaacgttc
    26041 gaagtaaaaa cagacccgga cactggtcat tgtttacatg gtggtgcacc tagctttgaa
    26101 gccaagcagt ggcattatac agtcatcaat ggtgaaaacg aagcatcggt cattttctat
    26161 cagactagcc cagatatgga aaacggattt cctggaactt tagatgtaga agtacggtat
    26221 acgctgacga acgatgatac atggcgagtg acggtccaag ggatcagtga ccgcaaaaca
    26281 gtattcaatc ctacaaatca tgtctatttc aatttaaccg gtgatccagc acagtcaatc
    26341 gacgaacata tactttggtt gaatagccga ttatttgcta cgctcaataa agatacaacg
    26401 cctacaggag aagtagtttc agtaagtggc acagcatttg acttccaacg tcctaaaaaa
    26461 ttaggtgagg tctttgccag tgattttcgc caatcaatga tagtgggcgg catcgatcat
    26521 ccatttttgt tgaaaaaaca atctggttta ctaaatgctg cggaattgac aagcccagat
    26581 gaaaaagtat cgatccaagt aaaaacagat gcttcaggaa tcgtgatttt tacagcaaat
    26641 tttggagaag atggaccgga aatgcgcggg aataaattag taaatcatgg cggtatcaca
    26701 tttgagactc aagaactgcc aggagcggag cgacttgaaa gttttggaga tgtcactctg
    26761 gaacctaacc aagtacgcga gtttgtaacg gaatacaaaa taaatataaa gaaatagaat
    26821 aaattaaaaa gggagtgtga cagtgtcaca tccccttttt aatttattct atttctttaa
    26881 aggcagatca agccagaatg atttgtctaa acttaacaag gttagtacag gaacagttgc
    26941 agctttaact gtacgagtag ttgtttctgg tatctgtctt gccgtaaaat tgttccacaa
    27001 atcccagatt gaagcgacac ggaagatgga agaagcgttg ttgacgcgtt ttatcgttga
    27061 aaattctaat cctgtgattg gcacgccatc tgttgtccat ttgattggca catcgaatcg
    27121 cttagacata ttgaggattt cagcgtttgc ttcttcagtt gttgctgctt cttttttcgg
    27181 ttcatcatat tttgtcaggt cgtacgcttc gatgatcgcg ttcaattttt gtgaatattg
    27241 gcgatctgta gcataacgtc cttccaaata tttggttgct tctttgtagt cttttgtttc
    27301 cgacttccaa gttggtttgt agaaatcagg attgccagtc agtccatttt tgatcaagtc
    27361 ggcatagtct tccaaacttt ccttgtaaga aggatattta cggaattgtg cgcggatttg
    27421 gtagctttgt ccggaactat cttgttcaag tgtattgaag gtcacgctgc ttcctttata
    27481 tgatcctttg ataccaaaaa ggttatgatt tggttcgctt gataataagc tgtttccaga
    27541 tccactttca aggatagctt gagccatcat gactgatgcg tagattcctt ctttttgccc
    27601 gatttcctgt gcatcatctg caatcttttt caagaactga tcagttgttt ggttttgact
    27661 gaaatggaac gagccatcta atccatctaa aatagatgag ccgcctgtca gcgaacctga
    27721 agcagcaggt aaacctgcta agtttactcg gacagcaaaa tcaggcgtga aatctgaaat
    27781 agaagttact cgaactttat ctcctggttg aggcgcatgg ataaattgtc cgttcccaat
    27841 atagatacct acatggtgag taacaccgga agaaggtccc cagaagacga ggtcgccagg
    27901 ttgggcctga cttactggaa tctgcgtacc tgcatattgc tgttcgcctg tccagccacc
    27961 gatataatga ccggttgctt tcatatatac gtaataagtc aaaccagaac agtcaaaagt
    28021 atttggacct tttgctcccc atacatatgg ttttccaaga tgcttgaatg cttctcgaac
    28081 gattgcttgt tggacattcg ttgtatttgt aggcaataca gcatcaattg gtgattttac
    28141 aacaaaatca gaagaagcag aagatggatt ctctataccg ctttgatttg ctgtatttgg
    28201 acgagatgaa gcattgttcg ttccgccatt cgatgaacca ttgtttggat ggtttggttc
    28261 tctctgagta tttccattgt tattcgatcc agatgggttt gtttgattcg aagaattccc
    28321 gctgttcgaa ttattgttat tattgtttga attatttgaa ccattattat tgttgttatt
    28381 acccacatct ggtttgtttg gcgtttccgg atctggtgta ctagggactt cttcactagg
    28441 atcagttggt ttctctgttg aagtatccgg tccagcttta aattctgcag taatagataa
    28501 attgttcgta cctactgtaa aggtctttgc atcataattt acttctttgg caccattaac
    28561 agcgactgaa gcaatttgtt caccttcagc tggcgtaata gtgtaagtta ccttcgtttc
    28621 cgctaataaa ccttctaccg ttccactttc cgtaatatcc aaaggttgct gttcagggga
    28681 atccgctgtc gaagcagtca gttggatctt accaatcaaa gaaggagcaa ttgtaaggga
    28741 atatgtctcg gctggctttt cattttctga tggatcagcc ggatcaattt cagttggctc
    28801 ggtcgatcct gttgttgagt tagttgttcc agttgggtct tctgtaaaag aatccgttgt
    28861 ttcactagta gctgagctgg atgtagtcgt atctgttgtg actgtttgat cagctatttg
    28921 attatctacg gcaaatacgg tattggtcga caaaacagac ggagcaatca gccaagtagc
    28981 agctagcaaa cgtatcgttt ttttattttt cataataaac tagtcctttt cctttcattg
    29041 attttctgtc ttattcagca ttcattagac attttttgga acagataatc gtgtcgaaaa
    29101 gctttttctt ttcataaatc tgtctgtgta ttctaaataa aacaatttgt aaataagcaa
    29161 cgagcattca ttcgtttttc tttgacgttc attttattgc atagaccacc tttgtttggg
    29221 gataaacaag tggggataaa aatggttatg catatgtaaa ttataccaaa gtttggaaag
    29281 tatcacaaaa atttataaaa ataatgatcc taaaaagaaa aagactgaaa tatgtgataa
    29341 acatctcata cttcagtctt tttcattaac tattcataag acattaggtc ttcatcaaac
    29401 ccgctaacga gagtagtgat cattgctacg actagactaa cagccagtcc tgctaagtac
    29461 cagaaaaaag taccggaaat gaatgcaggc aatgtggtca gactaccaaa tacaaaagcg
    29521 atcgctttca cttgggcaaa tcccattaca gctccaccag cagctgcacc aatgcaagca
    29581 gcaacaaatg gttttttcaa tgggatcgca attccgtaaa cagttggttc ggtcactccc
    29641 gcaagtaaaa tcgaagcaaa agcagaaccg gagatcgaac gggtttttga acgtttactt
    29701 cgcagaaata cacctaaagc tgcaccagcc attccaaaat tggctgctcc tgtcaacgga
    29761 acgattcggt cgaacccata agcagagata ttactgatca tgacagggtt tacagcccat
    29821 tggataccaa atattaccaa aatattccaa ccaccagcga tgattgcgcc actgatcggt
    29881 ccgttaatat ccatcatcca agtaattgcg gcagctaaac cttcgccaag gtaaacaccc
    29941 gcaggcccga ataccattaa cgtcaaagga accgtgataa ctaatgaaag taaaggtaca
    30001 aatactaatt gcatattttc gcgaatatat tttttgagga atttttcaac aaaagaataa
    30061 aagaaaatac ctaaaatcgc cggcatgaca gtagacgtat actgcatcag tactacagga
    30121 atccccagaa aatcagtagc tgctttgcca ctgtctgaaa gtaaagaggt cagattcggt
    30181 tcaatcagtg ctgcagcaat gacagccgca atatatccat tcactttaaa cgttttggca
    30241 gcagaaaaag caagaaagat tggcagaaaa taaaagacgg cattcgacgc agcagacaaa
    30301 atatgataag ttccgcttgt ttcactaagc cagccaatcg tagtcgctaa aacaaccaga
    30361 ccttttaata taccagaacc ggcaaacagc ggaatgatcg gcgtaaagat ttccgatatc
    30421 aaaccaaata gtttttcgat cggatttagc ttttctttcg gagctgaatg atcgatttga
    30481 cgcgtcaatt ccttgtaagc aggagccaat ccctgatcca tgattatttc tgcatatcta
    30541 tcgagtaaaa tgaaatactt aatggaaggg atttgctgtt ttaatttttc tgcattggct
    30601 actggctgtt ttttcaattt gatacgaagc cgagtcgcac atggaaggac agaatcaata
    30661 ttgtcttttc ctcccaactg ttcaatcagc atatgaatct gctcggacag taccatctgt
    30721 tcaggattca ttgtcgtttc cattagaaga ccactccact cactaatata atattggcgt
    30781 aaggtgtcat ttcgcctgta cgaataaatg catgacagtt attcaactct tttttcattt
    30841 cttcatgtgg gataaagcta atcggtgtat ctggtaacaa taatttgatt ttttccaata
    30901 tttccgggtt cattgtcttt atttcttccg ccaattcaat cgattgtacc tcaagttctt
    30961 ctaaaacgtt ttctaaaaca gataaaaaac ttggaagacc gtttgagaca gccaaatcta
    31021 ttttttcagt accaaagggg acaggcatgc ctgcatcccc gatacttaat ttatcaaagt
    31081 gccccatttg tgcgattact cgtgaaatat ctgaattgat tacttttcct tttttcatgt
    31141 ttgtttcttc ctctcattgt taattttaga ctgctgattg ttctaaagct tcgcggtaag
    31201 ggatagaagg ttgcgcacca taagactgca cagcaacaga agaggctaga tttccataaa
    31261 ggatcgcttc tttcaagtta ctaaggtctg gctgaagtgt gctgcttaat gcgccaataa
    31321 atgtatcacc tgcggctgtt gtgtcaacgg catccacttt aaaagcaggg acgataccgt
    31381 gttctttttc tgtatgatag aaagcgccgg cactgcctag tgtaatgatt actgttccaa
    31441 tacctaattc atggagtttt tcggctgctg cgaccaaact gttatgatct gtcactctga
    31501 ttcctgtaat gatttctgtt tctgtttcat ttggtataat gatatctgtc ttttcaagta
    31561 gttcagtagg aatcgtttca cgagctggtg caggattcag gatcgttgtt tttcctgcgt
    31621 cttttgcaat agaaaaagct aggatcgtcg catctaagct actttcaaac tgagcaataa
    31681 taaagtcact gtttgtaatc agttgcttgt tttttaggac ttcttgttca tggaaagcat
    31741 tatttgcccc tgcatggatc aagatactat tttctcctgc tgcgtctacc ataatcattg
    31801 cttgtccggt tgtggcgcct tggatttcag ctatcccaga tgtatcgatg ttttcttttg
    31861 tcagtagatc taataactgt tgtccttcgc tgtcagcccc aacgcctcca ataaaagatg
    31921 tccgtgcgcc tgaacgtttg gctgccactg cttggttggc acctttacct ccgccagcgt
    31981 gaaaaatctc atgcgcatgc atcgtttcgc ctggcttggg catgttggtt aaacgaaggg
    32041 tagtgtccat attaatactt ccaattactg taaccgtgtt cattttacaa acctccaact
    32101 atctcattta ttttgatggg aaaattattt tttaaaacgt tttagtaaaa cgttttaata
    32161 gttcgataaa aatatagcac accttgaaag ctatttcaag ggtgcagttg aaaatctttt
    32221 ttctaatcgt acaggtaatc ttttttcttc ccattctttt tctgggaatt ggatccgatc
    32281 taacaataac ttggcagatg tttgtcccaa ttcgaagatt ggttgtgcga tcgttgtcag
    32341 tttcggcttg atatactcgc acatatctat attatcatag ccaataatgc tgtagtcttc
    32401 agggatgctt tttccagctt cctctaatcc gcgatataat ccaaaagcta attcatcatt
    32461 taaagcaaac acaccagttg cagcagaatc aagaagttct gctgtgatct ggtagccacc
    32521 ttgttttgag aactgtgtag gtaagaggat cagttggtcg tgagggattt ggtaaacatc
    32581 aagagcagat ttaaacccct caatccgagc gtggacattt tccggtggat tttcaggata
    32641 gacaagggcg atcgtttgat gtcctagact aagcaagtgc atgcccgcta ggtaaccacc
    32701 gcgaaaatcg tctgttcgta cggcatcact aaatccttca gattttttct gatccaaaac
    32761 aatgaagggc cggccttgtt ttttcaaatt ttcgttgatt gcatctgtag agacagcaga
    32821 agtcgcgata atgaatccat ccacacctcg acgtgtgagc tcggctagat attcgatttc
    32881 tttttgatga tcagaatcag cattacataa tatcgtgacg aaattctgct tatacaagat
    32941 atcctcaatt cctcgcatca gtgtactgaa gaatggattc gtgatatcag gaacgagtac
    33001 accaattgtt ttcgtttcct tggtaatcat ttgtctagca aaatagtcag gctgatagcc
    33061 taattcttct ttggcagcta aaactttctg aacagttttc ggactgaatt tctccgtatt
    33121 tccatttaat atcaaggaga cagttgtgat tgaaacgccg gaaagtttag cgacttcttt
    33181 gattgtgatc ttttttttca ccatgttcat actcctatct aaatcctgtg gttattttcc
    33241 catgaaatca aaaagaagta aatgaaaatc acgtgtgcca gtacttattt gctttgttgg
    33301 atagcttcga ttatttgttt cgttgagcgt actcgtgcag ttttcggaaa tatctttttt
    33361 atgaacaatt gatgggattc tttgtcacga tcactgcaag catcttcagc aagcacgata
    33421 tggtacccgt gttgaaaggc atctaatgca gtagcatata caccgtttgt tgtcgctaca
    33481 ccgcttaaaa tgatagtttc gattccacgc cggcgaagtt gaagatcaag agaagtacca
    33541 aaaaaagcac ttggattgta ttttgtgata gtcaacatat tatctgtatc tttcaaagaa
    33601 tccttcaaaa gtaaatcagt gaattctgga ggtacagaag cagtcattcc acccatatca
    33661 gtttgttgac tcaaataagg gaaagtggag atgtctacgt tcactaaaac tttcaaggca
    33721 gcggtacgtt tcaatgttct tactaacaaa tcattgtttg tcagaataga tgctgcagtg
    33781 tgtggagaga gtgtaccgtt atttacgatc tctttttgca tgtcgatcgc gacaaaagca
    33841 gtttttgata aatcaaaaat catattttcc tttaaatcat tcatgatgtt ccttctttca
    33901 aataacaatg ttttttatgt aagtaaatca taaatcgttt atttgtcaac taaattaaag
    33961 gattcctttc tttagtctag agaaattcag tggtaaaata aataagtgtg agaaaacgca
    34021 ttcgatgcat agatatagcg agaaatatcg tgaaaatgga ggaatcagag tgaagtatgt
    34081 cgaagtaaaa aatgaataca aacgatacaa aatgggagaa acgaccatta cagcaaatga
    34141 cgatatttct ttttcaattg aaaaaggcga attagtgatt atacttggtc caagtggagc
    34201 aggaaagtca acgattctta atattttagg tgggatggat acacctgatg aaggtcagat
    34261 cattattgat gacacagata ttgcgcaatt ttcagataaa cagcttactg cttaccgacg
    34321 aacagatgta gggttcgttt tccaattcta caatctcgtt cctaatctaa cagcaaaaga
    34381 aaatgtggaa ttggcaacgg aagtttctcc tgatgcgctt gatcctgtag aggtattgag
    34441 gcaagtgggc ctagctcatc gattgaataa ctttccgtcc caattatcag gaggcgaaca
    34501 gcagagggtt tcaattgctc gtgcactagc taaaaatccc aaacttcttt tatgtgatga
    34561 accgacaggc gcgctggatt ttgaaacggg caagcaagta ttgaaattat tgcaaaacgc
    34621 tagcagacaa cacggcaata ccgttttgat cattacacat aattctgctt tagcgcccat
    34681 cgctgataga gtcattcaca ttaatgatgc taaagtaagg tctgttgaat taaatgatca
    34741 tccttcatcc attgatgaga ttgtatggta gggggatttt atgaaaacaa gaacatatct
    34801 taaagcaggt tttcgcgaaa ttcggcaatc taaaggacga ttcattgcaa tcatccttat
    34861 tgtcatgcta ggaacacttt tatttgtagg tgtcaaaact gctggacctg tcatgcaaaa
    34921 aacgatggat cactatgttg gtacagcagg actttctgat ttgcaaatcg tttctactgg
    34981 tggcttgaca caaaaagata ttgctcaagc agaaaagatc ccagatgcaa aagtagaaac
    35041 aggaaaacag atctattatt ccaatactgg caaaaacgaa gtgattcaaa tattttctta
    35101 taacaaaaat aacaagcaga acaagctaca attaactgat ggaaaactcc cggaaaaacc
    35161 aaaccagctt gtattggatg aaaaagcgga agatgaaggg tataaaatcg gtgatattta
    35221 tcagattgat tcagatgaat tgaaagaaaa agagtatacc atcacgggct ttgtccgttc
    35281 tccattgttc atcaacaatt tggagagagg atacgcgaac gtcggaaatg gtagcgtcga
    35341 ttattttgtc tatttacctg aatccgtttt taaaacagat atttattctg tcttatatct
    35401 tgattttaca aacgtaaaga atttgaatac gtacagcaaa gcttacaaag ataaaatgga
    35461 gcaaaatcaa gaaaaggcag aaaagtattt acaagatcga cccgaagaac gcttagaaga
    35521 gctgaaaaaa tcggccaacg aagaattaga accggcacag caaaaaatag cggatggcaa
    35581 agcacaaaca acgcaagcaa gaacacggtt agaagatgct aaaaaacagt tagcgcaaca
    35641 gtcagcaact atccagcagc ttcctgaagc gcaacgaaca atcgctgttc aaacattatc
    35701 tcaacaagaa gctcaacttg ctgaacaaga aaggcaatta gttgagaaag aacgtgaact
    35761 ggcctctgca gaggaagaat tgaatcgaaa tgcagaaaaa attgaaaatt taactaaacc
    35821 atcataccta tacaatgaac gttcagaaaa tgtcggtttt caagaatttg gtgatctgtc
    35881 tgatcgtatc gctgcgattg ccaatgtttt tcctgttttc tttttcttta ttgccgcatt
    35941 gatcaccttt acgacaatga cacgtatggt agaagaaaac cgcagggaaa tcgggacatt
    36001 aaaggcgtta ggttatacga aagttgaaat cgcaaaaaaa tatgcaatct atgcaagtct
    36061 agcctcaggg ataggtattg ttttaggaac gatattagga acgaatcttt tgccaaggat
    36121 catttttgag ctgtctaacg agcggtatga tattgggagt gcgcttattt tttatgactg
    36181 gccgccgatt ttacaagcag ctgccgcatt cttcattgcc gcatttggcg ctgcaatgat
    36241 cgttttattc aaagatttaa gagaacggcc tgctgcattg cttcaaccga aagcaccgaa
    36301 gccagggaaa cgcatttttc ttgaatacat cactccgctg tggtcacgcc ttagctttaa
    36361 tcaaaaaatc agttaccgaa atctcttccg atataagtca agaatgctta tggcgattat
    36421 cggaattgct ggatgtgccg ggctgatggt tgcaggcgtg ggattgaaag attctctaag
    36481 ttctgtttca gccaaacaat ttggaccgat cattgactat caagcaatcg ttacattgga
    36541 ttcatccacg gaagatagtc gtcaaaaagc agcggatatg ctgcagaagc aagaaaaagt
    36601 aaatgagatc ctagctattc atactcaaac cgtagaattg agaaaaaaag gacatgcttc
    36661 gcaaagtctg acagtgatcg taccaagtaa aacagctgat ttggatcgtt ttatccattt
    36721 aactgatctt gaagagaacc cacgctcctt gcctaaaaca ggaatcgcta ttacgcaaaa
    36781 agtagcagaa ctatttgact tatctacagg agatcatatt tcgctttatg atgaagatca
    36841 aaaagaatgg aaagtcgaag taaaagaaat cgtgaaaaac tatctaggta gctttattta
    36901 tatgtcccct gaatattatg cttcagttac tgatcaatcg atgatggata atgcattttt
    36961 gctgcgtaca gataagatga caacaaaaga agaagaaatg ctttccgaga aactgcttgc
    37021 cacagacgct gtgacaaata cgtctttcat gtccaaacaa atcgaaacgc aagaagaatc
    37081 aatggcgaac ttagactcgg ttgtcttaat ctttgtcgta ttatcaggac tgctggcttt
    37141 tatcgtcttg tataatctaa ctaatatcaa tatttccgag cgtgtacgcg aattatctac
    37201 aataaaagtc cttggatttt ttgataaaga agtcacgatg tacattgttc gagaaaatat
    37261 catctttact cttttaggaa tcatcggagg atttggtgta ggatatatat tgactgactt
    37321 catcttgcaa caagcgtcta tggagaatgt catctttcca ttagtgatca catggtgggc
    37381 ttatgtctta tcagcaggat taactatcgt atttacggtt attgtgatga ttgttaccca
    37441 tttcaaatta aagcatatcg atatgattga tgcgttgaaa tcgaatgaat aaaaacagag
    37501 gttgtgaaat cagcggtttg acctgagtat tagagaaaca aacggcaaaa tagtttttca
    37561 tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacacca tgaatcagag
    37621 gttgtaaaaa agccgtcctg catcgagcaa aaagaatact caaataaaat tagctcctca
    37681 tgttttacat ttgagaagac tgattgccgt agataaaagc ttttgaacac catttataga
    37741 agaaacaaga atattttgct attttaaaca agaggataga caaatacatg tctgatctct
    37801 tgttttttat tgggcaacag acctcttaga atgtataaag ataaatttta caaacgcttt
    37861 cggttcagtt ataataataa atgataactt gtatatataa gttgtggtag gtaataaatc
    37921 agttgaatgg aggtaaatat ccatgacatt taaagacaaa gtcatttacc aaatctatcc
    37981 caaatcttac aaagacagta atggtgatgg aattggagat ttaaaaggaa tcaaagaaaa
    38041 actcccgtat ctgaatgatc taggcatcga catgatttgg ctaaacccta tttatccaag
    38101 ccctcaaaaa gacaacggtt atgatatctc tgattacaca gccatcgatc ctatctttgg
    38161 tacgatggag gaattcgaac agctaatagc cgaagcaaag aaataccgga tagaaatcat
    38221 gctcgatatg gtgctgaatc acgtttcgac agaacatgaa tggttcaaaa aagcactagc
    38281 aggggaccag cattatcagg acttcttcat tttaagagaa gagccaacgg attgggtatc
    38341 aaaatttggt ggaagtgctt ggtcgccatt tggagatacg gggaaatatt atttgcactt
    38401 atatgatcgg acacaagctg acttgaactg gcggaaccaa gcagtaagag aggaactatt
    38461 caaagttgtt cgtttttgga tggaaaaagg ggtaaaagga ttccgtttcg atgttatcaa
    38521 tgttatcggt aaagacgaac aattgaaaaa taataaagaa aatgatggca aacctgaata
    38581 tacggacaaa ccaatcaccc atacgtatct aaaagaattg aaccaagcaa cgtttgggac
    38641 ggattccact atcatcacag tcggtgaaat gagctctacg acgatcgaaa attgtatctt
    38701 gtatacagaa cctagtagag aagaattatc aatggtcttt aatttccatc atttgaaagt
    38761 cgattatgaa aatgggaata aatggtctac tcctccattt gattttgcag aattaaagcg
    38821 actatttcat acatggggag aaaagatgag tgagggtaac ggctggaatg ctctattttt
    38881 taataatcat gatcagccac gtgcgctcaa tcgatttgta gctatcgatc agtatcgaaa
    38941 acaaggagca gagatgctag caaccatgat ccatttgaac cgtgggacgc cctatattta
    39001 tatgggagaa gaaatcggca tgatcgaccc agactattca tcgatttccg actatattga
    39061 cgtagaaagt ttgaatgctt ataagttact ccttgaacaa ggattcacag aaaaagaagc
    39121 gtttcgtcgg atcaaagcaa aatctcgcga taactctcga acacccatgc aatggtcaga
    39181 cacagaacaa gcaggattta ctacagggaa accttggtta aaagttggag gcaagctaga
    39241 agagattaat gtagaaaaag aactatcttc tgaagattct attttgtcct attacaagaa
    39301 attgattcgg ctgagaaaaa catatccaat cgttgcacaa ggagattatc atgcttatga
    39361 agcaaatcat ccggaagttt atggctttct tcgccaattt gaaggacagc agctgcttgt
    39421 attaacaaat ttctatgata aagatacaag gatcgccatc ccagaaggat tcacagaagc
    39481 caatattctt atcgataatt attccgatac tgttcttcat caaagtctgg agctaaaacc
    39541 ataccaggca attgctttgc tgaaaaatta aaacaaaaac acaaaacgtc gttcctacga
    39601 gctattctcg taagatcgac gttttgtgtt ttatttaaaa taatcttctt cagaaaatga
    39661 agagttttca tactctcctt tatcgccata aaatttattg tagcgttgtt tgaatttacg
    39721 gaaaataaaa gtaacgagta atttgactaa cgtatagata ggaataccaa aaataacgcc
    39781 cacaattccc attagatcac ccatgacaag taaaacgatt aagatcgtaa tcggatggat
    39841 ctgtaaacga tcacccatta ctcgaggaat caccaagtca ccgtggagaa gttgtacggc
    39901 aaaccagaca atgacaaatt tgacagccat aaaagtagag tcttggaatg caatgatcaa
    39961 acctggaaag aaggcgataa acggcccaat atatggaatg atacataaca acccagcaga
    40021 aatagctaaa acactagcaa attctaatcc gatcagtaag aaacaaaccc agtagactgc
    40081 tccaaggata aatgaagcaa tgatttgccc ctttagaaat gaacccaatt gttgattagc
    40141 aatctttgtc aaatttttaa aatctgtacg aaatgctggt gggacaatcg ctaaaactga
    40201 ctgataaaat ttttgaggat ctctcaaaag gaaaaaagcg acaattggac cagtaaataa
    40261 agtaataaaa atagctgtaa cagttgaaaa aatgttgctg atccgttgtg cgccactttc
    40321 ccaataattt ccaataaatc cagctatatc agacgtcacg tcgtcaatag aagcgaaaaa
    40381 ttgattaaat gaatcggcaa aaggtgtttt ctccaaaaat tgtcggagac tctcttgaaa
    40441 atcttgaaac aaatctggca aactactgat caatgtcttt gcctgttctt caagaaaagg
    40501 aataagccat atgcttccaa gccccaataa aaataaaata atcacataaa cgataatgac
    40561 tgacaagttc ctcgaaaggt gcttgctcaa acgtttgatg actggttcca aaagataata
    40621 caagatcagt gcaaacaata atgggggcaa gatagtagcg ataatgattc cgacaggctt
    40681 gaatataaac gagatctgat ggaaaaaata aatgatcagc gcaagtaaga taactattcc
    40741 taaaacatag taagaggttt ttcctcctaa aaagcggatc aaacgattcg ttgtatctgt
    40801 ttcttttttc actctttttc ctcctttatc tataacttca ttatagacaa aagcgggtat
    40861 aaaaggaaaa tgatagaggt tgattgcaaa aatatcgtca atcattcata taaactttct
    40921 catcaattaa aataagaaaa cgcttgacag ttcttttaac catatgataa attaaatcct
    40981 gttgctaaaa cgtaactatt acggtttgcg aaaagcgaat cggaacattc aaatgaaaga
    41041 agatgagaag aggagtgtca taaatgaaac gattgatagg tatattggcc atgctggttt
    41101 tagcaggtat gttaactgct tgcggggcaa gtgggaaagc cgaggacagt aaagaaaaat
    41161 tgagcgtgat gacgaccttt tatcccatgt atgattttac aaaagcaatc gtcggggatg
    41221 aaggagaagt agagttattg attccagcag ggactgattc ccacgattat gaaccttctg
    41281 ctaaagacat ggcaaagatc caagatacag atatctttgt ttataatgat gaaaacatgg
    41341 aaacatgggt ccccgcaatc caaaaaacat tacaagaagg caatgtccat acgataaaag
    41401 cgacagaagg tatgctttta cttccgggaa gtgaagaagg acatgatcat gaccatgaac
    41461 acggggaaga aggccataca catgagctag acccacatgt atggctagct ccaagtttag
    41521 caatcaagca ggtagcaaac atacgtgatc agctgattga agcttaccca gaaaaacagg
    41581 aagtatggac aaaaaatgca gcagcctata ccgagaaact tcaagcactc catcagcttt
    41641 atcaagaaac ctttaagcaa gcaaaacaaa gatcttttgt cacgcaacat gctgcattca
    41701 actatctagc gttagaatat ggattgaatc aagtatcgat tgctggtctt tcttctagtg
    41761 aagaaccgtc tgcggcgaga attgctgaac tgaaacactt tgttaaagaa catggaatca
    41821 actatattta ttttgaagaa aacgccaaag atagtattgc cagaacgtta gcaaacgaag
    41881 caggtgtatc tttagaagta ttgaatcctt tggaaggatt gacgaatgaa caaatagaaa
    41941 atggagaaaa ctatctttct atcatggaag caaacctcga agcgttgaaa aaaacgacag
    42001 agacagaaaa cccgctagaa gatactttga cccccaaaaa agaaaagagc gtctacaacg
    42061 gttattttga agacgaggat gtacaagatc gctctctttc agattgggca ggaacttggc
    42121 aaacagtaga tacgtatgta gaagatggga cttttgatcc tgtttttgaa tataaagaaa
    42181 aattgaatca ggataagaca gcacaagaat ataaagaata ttatacgaag ggctatcaaa
    42241 cagatattgc ttcaatcaag atcagtgaga aagagatggc atttacgttt aagaatggaa
    42301 caacgaaacg ttcaaattat cgttatgtag ggaaagaaat cttgacctac gaggcaggaa
    42361 accgtggcgt aaggtatcta ttcgaagcag aagataagga aagtggcgct tttagatata
    42421 ttcaattcag tgatcacacg attgcaccgg ctgactccga acattttcat ttatatgcag
    42481 gaaatgaaag tcaagaagta ttgctgaaag aaatggagaa ttggccaaca ttttatccag
    42541 atacaatgga tggacgtgaa attgcacagg aaatgctttt gcactgatag gcaaaaaaga
    42601 accgaagggt ttggatcggc tggtcattta gtcggtccaa actattcggt tctttttatg
    42661 aaatcaattt ctttaatcca cggatagagg ctgggatggt ctcgccgttt gccaacgtga
    42721 cttctctggt ttttttatta atcgaccgca cattttgtgt attgataaca taggatttat
    42781 gacaacggat aaaattccga tgcattttct cgatttcttt gatcttctca tagaattgta
    42841 attgggcatg agtcaaatgg acttccagtt tatgtggcgc tcctagcgaa gtagaaaaat
    42901 attggatgtc tttgatcggt aaaaatttga tctcatcatt aaactctatt ttgaagatat
    42961 ctttttggat ttgggacatt tgaaaatctt cgaaaatttt gctcaggata tgctcgacat
    43021 tttcttttaa atcataaaga tcttctttga cgatataatc agtcggttcg atgttgcttt
    43081 ttaagatttt catcgacatt tccgtatggg aagtcacata gattattttt cctaaaggat
    43141 ctaattcacg gatcaattta ccgatcgcta caccatccat ttcactgtct tctagttcga
    43201 tatctaaaaa gtaaatacca aaagaagaag ttctgatctt ggctgcattg agaagttctt
    43261 ccggatcaga ggtagaaata tggacataac tgtctaagtt ttcaatcatg attctatttt
    43321 tgatcaccgt tgataaaact tctaattgtt ttggatcgtc ttcacaaata taaatgggaa
    43381 tcatatcatt actcctttat tttatttgta tataaatcgt ttgagaaaaa cgctggtttt
    43441 caattgatgt ttcaaggaaa agataaggat tggtctttgt caattcatcc aagataaaca
    43501 agccaaggcc ttcgtttttt ggatttgttt ttgttgagaa ccctttttgt ttcaactggt
    43561 ttaacggtaa tgtatttgtt gttgtattga tcacacgaat catcacggaa tgattcttct
    43621 tgagtatggt caattcgatt tttttcttct ttgcagcact agctccttca atcgcattgt
    43681 ccaagataat accaagcata cgtacaaggt ttaccgtatg tttcgtatcc agttcgattg
    43741 gctcaggaaa atgaagctgg acgatcaacc ctttttcctg tgccatcatg agttttaatg
    43801 acagtaaact acggatctca ggaactttca tattatccaa catacttaga ttggccggaa
    43861 aaaggttcat catctggcgt gtaggtaata tcgtttgatc ataataagac cgtaatcctt
    43921 ctaagtcgcc ttctgaaata tagctgtgaa gagaaaaaag cagattttgg taatcatgtt
    43981 tgaattctct caagtcttga tagttttttt ctagatcttt gatataatcc tgttgcatcc
    44041 tgacttgttg ctctaataac tgatcagcta atttcttatt agagattttc caataataaa
    44101 ccaagatgat caggccaaca cacagatata gaatgaaaaa actcgtattc aaagctaaga
    44161 catcaggtgt ttcaccagaa aaacgggtat aaaaaataat gatatagtat gtaaataata
    44221 tcaatgtccc gatcgtaccg atcatacggc ggtccacagt gtgaaaccaa gtctctaacg
    44281 atttttttaa acaaaaagct aataaagcag ataaaaaagc ggataagaca atgtgaaaat
    44341 actgcaatga atctcctggt tcaataaccg aagatttcaa aacaaaaaaa tcgccgatgc
    44401 ttgttaagtg atctcctaaa agcgacgtca ataacccaaa aggaagcgcg taaaccaatt
    44461 gttgacgcga agtcgaaaag aagaaaaaag taagcatcag cattcctata gcaattagag
    44521 cagtaaaaat ccctaaaatc gaatagaccc atccaatcaa aatacaagaa atcagaatga
    44581 ctcccgcaaa cagatatttg tatcggatgt gatggtcaat caataagata caaattgtgt
    44641 aaatcaaata ttgcaacgct atggaccata aaaacataaa gtacagctcc cattgatttt
    44701 taccaaatta tagcacaatt ggcgtattat ttttttaatt tttcagggat tttgaattca
    44761 gaactcatac caaagcagca gccagataca aaaaagtcag ataagttagt taattgttta
    44821 atgattgttt ttttcatgaa agattcctcc aaaattcatc aagtagtttg taataggaag
    44881 caacgtagct atttctaaaa caatcccaag tagcaaatag gtagaaaagt aagaagctga
    44941 gaaaaataac gtaatgagag aaaaaattag aaacatgctg atcgccttct ttaataatgg
    45001 gggacgtttc tcgggttcaa tgggattgat tgctgtacct cttgatccat agcgaagcag
    45061 taacaaaaag cagctgatta acaaaaagac catcattggg aaggagatag tcaattgcag
    45121 atgtttcatc accaagggaa cgccccataa ataaagtagt gtccacagca gacaaacgaa
    45181 ttcagagtcg gaatgcaatc cataagcata tctgcggatg cagatataag aaagaaaggt
    45241 gattcctgtt tccgcccatg agcctgtcac cagagaaaag actagaacga ccgctagttt
    45301 tccaagatta ttcaataaaa cttctaagac aaattttact tggacataca ccatatcttc
    45361 ttccgatttg tctccgctga ataaggcttc taataatttg ttcacaactt tatctttcat
    45421 ctcatacgta cctccaccac aaattttatg ctaaaaaaaa taaaaaacgt cttttgtttc
    45481 ataaaaagtg gttttgacat caaaaccgtc atgatctcct aaaaaaatct tcgttttcca
    45541 agaaccttac caaaaaaagt gacagttttg atacgaaaag tactttttat gacaagtttg
    45601 tgctttttcg agtgatttat gttaaaaaat tactgacctt ataaaaggtg atggagggat
    45661 tcttatggaa aatgaacaat tgtttgaagt cggcgaaaca tatgcattta aatctgattt
    45721 atttgaatca ccaa
//
LOCUS       DACBYO010000013        45546 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.013, whole genome shotgun sequence.
ACCESSION   DACBYO010000013 DACBYO010000000
VERSION     DACBYO010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.013"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(223..1071)
                     /locus_tag="IVD26_000701"
     CDS             complement(223..1071)
                     /locus_tag="IVD26_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP6078701.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1295..3235)
                     /gene="thrS"
                     /locus_tag="IVD26_000702"
     CDS             complement(1295..3235)
                     /gene="thrS"
                     /locus_tag="IVD26_000702"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAP6078702.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3572..3751)
                     /locus_tag="IVD26_000703"
     CDS             complement(3572..3751)
                     /locus_tag="IVD26_000703"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAP6078703.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3798..5621)
                     /gene="cadA"
                     /locus_tag="IVD26_000704"
     CDS             complement(3798..5621)
                     /gene="cadA"
                     /locus_tag="IVD26_000704"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAP6078704.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5899..8178
                     /locus_tag="IVD26_000705"
     CDS             5899..8178
                     /locus_tag="IVD26_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6078705.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8271..8918)
                     /locus_tag="IVD26_000706"
     CDS             complement(8271..8918)
                     /locus_tag="IVD26_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078706.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(9097..9816)
                     /locus_tag="IVD26_000707"
     CDS             complement(9097..9816)
                     /locus_tag="IVD26_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP6078707.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9947..11098)
                     /locus_tag="IVD26_000708"
     CDS             complement(9947..11098)
                     /locus_tag="IVD26_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAP6078708.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11315..12055)
                     /locus_tag="IVD26_000709"
     CDS             complement(11315..12055)
                     /locus_tag="IVD26_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6078709.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(12059..12382)
                     /gene="rsfS"
                     /locus_tag="IVD26_000710"
     CDS             complement(12059..12382)
                     /gene="rsfS"
                     /locus_tag="IVD26_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAP6078710.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12439..13032)
                     /locus_tag="IVD26_000711"
     CDS             complement(12439..13032)
                     /locus_tag="IVD26_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP6078711.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(13016..13663)
                     /locus_tag="IVD26_000712"
     CDS             complement(13016..13663)
                     /locus_tag="IVD26_000712"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAP6078712.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13676..13987)
                     /gene="yhbY"
                     /locus_tag="IVD26_000713"
     CDS             complement(13676..13987)
                     /gene="yhbY"
                     /locus_tag="IVD26_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAP6078713.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(14003..15112)
                     /gene="yqeH"
                     /locus_tag="IVD26_000714"
     CDS             complement(14003..15112)
                     /gene="yqeH"
                     /locus_tag="IVD26_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAP6078714.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(15109..15636)
                     /locus_tag="IVD26_000715"
     CDS             complement(15109..15636)
                     /locus_tag="IVD26_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAP6078715.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15816..16601)
                     /locus_tag="IVD26_000716"
     CDS             complement(15816..16601)
                     /locus_tag="IVD26_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAP6078716.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16594..17463)
                     /locus_tag="IVD26_000717"
     CDS             complement(16594..17463)
                     /locus_tag="IVD26_000717"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAP6078717.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17464..18843)
                     /locus_tag="IVD26_000718"
     CDS             complement(17464..18843)
                     /locus_tag="IVD26_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAP6078718.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18851..19270)
                     /gene="fabZ"
                     /locus_tag="IVD26_000719"
     CDS             complement(18851..19270)
                     /gene="fabZ"
                     /locus_tag="IVD26_000719"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP6078719.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19295..19771)
                     /gene="accB"
                     /locus_tag="IVD26_000720"
     CDS             complement(19295..19771)
                     /gene="accB"
                     /locus_tag="IVD26_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAP6078720.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19774..21009)
                     /gene="fabF"
                     /locus_tag="IVD26_000721"
     CDS             complement(19774..21009)
                     /gene="fabF"
                     /locus_tag="IVD26_000721"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAP6078721.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(21028..21765)
                     /gene="fabG"
                     /locus_tag="IVD26_000722"
     CDS             complement(21028..21765)
                     /gene="fabG"
                     /locus_tag="IVD26_000722"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAP6078722.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21777..22694)
                     /gene="fabD"
                     /locus_tag="IVD26_000723"
     CDS             complement(21777..22694)
                     /gene="fabD"
                     /locus_tag="IVD26_000723"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP6078723.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22801..23025)
                     /locus_tag="IVD26_000724"
     CDS             complement(22801..23025)
                     /locus_tag="IVD26_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP6078724.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(23078..24040)
                     /locus_tag="IVD26_000725"
     CDS             complement(23078..24040)
                     /locus_tag="IVD26_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAP6078725.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(24050..24490)
                     /locus_tag="IVD26_000726"
     CDS             complement(24050..24490)
                     /locus_tag="IVD26_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6078726.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24796..25761
                     /locus_tag="IVD26_000727"
     CDS             24796..25761
                     /locus_tag="IVD26_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP6078727.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25818..26048)
                     /locus_tag="IVD26_000728"
     CDS             complement(25818..26048)
                     /locus_tag="IVD26_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAP6078728.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(26134..27021)
                     /locus_tag="IVD26_000729"
     CDS             complement(26134..27021)
                     /locus_tag="IVD26_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAP6078729.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(27110..28333)
                     /locus_tag="IVD26_000730"
     CDS             complement(27110..28333)
                     /locus_tag="IVD26_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP6078730.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28350..29429)
                     /locus_tag="IVD26_000731"
     CDS             complement(28350..29429)
                     /locus_tag="IVD26_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP6078731.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            complement(29560..31287)
                     /gene="ptsP"
                     /locus_tag="IVD26_000732"
     CDS             complement(29560..31287)
                     /gene="ptsP"
                     /locus_tag="IVD26_000732"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAP6078732.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31287..31553)
                     /locus_tag="IVD26_000733"
     CDS             complement(31287..31553)
                     /locus_tag="IVD26_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAP6078733.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            32032..34266
                     /locus_tag="IVD26_000734"
     CDS             32032..34266
                     /locus_tag="IVD26_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP6078734.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34414..34734
                     /locus_tag="IVD26_000735"
     CDS             34414..34734
                     /locus_tag="IVD26_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAP6078735.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34939..35163)
                     /locus_tag="IVD26_000736"
     CDS             complement(34939..35163)
                     /locus_tag="IVD26_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAP6078736.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(35361..36941)
                     /locus_tag="IVD26_000737"
     CDS             complement(35361..36941)
                     /locus_tag="IVD26_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAP6078737.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(37342..38718)
                     /locus_tag="IVD26_000738"
     CDS             complement(37342..38718)
                     /locus_tag="IVD26_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP6078738.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(38846..39964)
                     /locus_tag="IVD26_000739"
     CDS             complement(38846..39964)
                     /locus_tag="IVD26_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP6078739.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            40106..40540
                     /locus_tag="IVD26_000740"
     CDS             40106..40540
                     /locus_tag="IVD26_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6078740.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(40618..41151)
                     /locus_tag="IVD26_000741"
     CDS             complement(40618..41151)
                     /locus_tag="IVD26_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAP6078741.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(41245..42423)
                     /gene="mutY"
                     /locus_tag="IVD26_000742"
     CDS             complement(41245..42423)
                     /gene="mutY"
                     /locus_tag="IVD26_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAP6078742.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(42416..43213)
                     /gene="recX"
                     /locus_tag="IVD26_000743"
     CDS             complement(42416..43213)
                     /gene="recX"
                     /locus_tag="IVD26_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAP6078743.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            43320..44702
                     /gene="rlmD"
                     /locus_tag="IVD26_000744"
     CDS             43320..44702
                     /gene="rlmD"
                     /locus_tag="IVD26_000744"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP6078744.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(44876..45454)
                     /locus_tag="IVD26_000745"
     CDS             complement(44876..45454)
                     /locus_tag="IVD26_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAP6078745.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
BASE COUNT        12983 a         9710 c         7906 g        14947 t
ORIGIN      
        1 gggcggagca agaaattctt tacctaattt caagataaaa tcaacttttt gtttcacagc
       61 aatcacttaa agttacatat ccaactattt ttttcattaa aaaataaact tatttttgaa
      121 aattatgttt tcttaagtcg tgaaacactt tgatggatca tttatttgtg gaaaactacg
      181 ttttgttatt ctaaaaaact tatataaaaa atagtaaggt ttttatttcg aatccataaa
      241 atattcttgg attgcttctc gtgttttttt cactttttcg ctaagctttt cgtttttagc
      301 catatagaaa taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg aattagttgc
      361 cgcacttcga ttcgtgattt cttttggtct agatgtttgt acgagtacat cggctatctt
      421 gctaagcggg ttatttccaa attgcgtcaa cgcaatgatt tcgatattca tgcttttcgc
      481 cagctcggct aatgcgacta catctgcact tctacctgag tttgaaacaa gccaaagcac
      541 tttctttttc tcattgctga caagttgcgg gagcaagacg tggatatctt tttcaaaaat
      601 gattggctta ccgacacgag accatttttg cagaatatct tctactacta aagaagaggc
      661 gccaacccca tataaaaaaa cagtctctgc cgattccaaa cactctacga ctttttggat
      721 cgtttcttct tctagaatat ctactgtttc ttttatcgct acttgtgcat tgttaccaag
      781 tttgtttttg atagagtaaa aggactcatt tgcttctata tcactaaaac cttcatcgat
      841 tccagtctgt agttctgttg aaatcgtgat tttgaagtcc gtcagacttt gaaaaccgat
      901 ttttttggaa aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg ctaattcatt
      961 agctgtcatt gtagggacct tctcaatatt accgataatg tagttggcca actttttttc
     1021 tgctgaagaa taatcttcca tcatactttc aatacgacta attacgctca taagttcctc
     1081 caccctttta atgatagtct atgtaagtat accatatcag acccttattc acggtcgtat
     1141 actggataaa aaacaaaaaa acaatccgcc caacagaata tcttatccca tcaatcccac
     1201 agattctatt gagcatctgt gtctttgagg aatacctgtt atctattgtt cggattgctt
     1261 tctatctact acttttttac aggaaattta cctattagtt ttctctgctg taatttttga
     1321 cttctgcttc catagcatca ataaagatat tcaaatcttc tacagctgtt tctttacttc
     1381 cataacgacg tacgttcact gttgcatctt ccaattcctt gtctccaaca actaattggt
     1441 aagggatctt ttgtgtttga gaggcacgta tcttatagcc cattttttca ttacgatcat
     1501 caacttctac acgcaacccc ttcatttgca aacgttcttt gatttcataa gcataatcgc
     1561 catgtgcatc aacagaaaca gggatgattg ttgcttgtat aggtgccaac catgttggaa
     1621 aagcgccttt gtatacttct gttaaataag cgacaaaacg ttccattgta gaaacaattc
     1681 cgcggtggat aactactgga cgatgcgtat tttccccgtc ttctccaaca tatgtcaaat
     1741 caaagcgctc tggcaataag aagtctaatt gtatagttga taatgtttct tctgtaccaa
     1801 gagctgtttt gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg ccttctgctt
     1861 caaagtaatc tagttctaat tcatccatag cggctttcag cattgcttgg gctttttccc
     1921 acattgcgtc atcatcaaaa tatttatctg tattgtttgg atcgcgatag ctcaagcgga
     1981 aacgataatc tgtaatattg aagtcagcat atactgccac catcaattca agcgtacgtt
     2041 taaattcatc tttgatttga tcaggacgaa caaatgtatg accatcattc aacgtcattt
     2101 ctcgtacacg ttgtaaacct gacaaagcac ctgatttttc atagcgatgc atcattccta
     2161 attcagcgat acgaattggt aattcacgat aagaatggat cgtgtttttg tagaccatca
     2221 tgtgatgagg gcagttcatt gggcgaagaa caagcatttc gccatctccc atatccattg
     2281 gcgggaacat gtcttcttga taatgatccc agtgtccaga tgttttgtac aactcaacat
     2341 ctcccattat tggtgtatat acatgttggt aacctagact aacttctttg tctacgatat
     2401 aacgttcgat cgtgcgtcgg attgttgccc cttttggaag ccagaatggc aaaccagaac
     2461 ctacttctgg ggaaaccatg aacaagtcaa gttcttttcc tagtttacga tggtctcttt
     2521 cttttgcttc ttcacggaga cggatatatt ctttcaaagc tttcttgtca aaaaaggctg
     2581 tcccgtatac acgttgcatc atttgattgt ttgagtttcc acgccaataa gcacctgcca
     2641 ctgataataa tttaaatact tgtatacggc cagtggatgg aacatgtggt ccacgacaca
     2701 aatcgatgaa ttcgccttgt tgataagcag taatcacttc ttcttctggc aattcactaa
     2761 tcagttctac tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt tttgaaagaa
     2821 cacggcgttc gatcggcaga ttttctttga cgattttcat catttctgct tcgattgccg
     2881 gcaaatcttc tgcagttact tggttttgtc cattatctgt atcgtagtaa aaccctgaat
     2941 cgatagctgg tccaacgcca aagtggatat ttggatagag gcgacgcatg gcttgggcca
     3001 tcaaatgagc tgctgaatga cggactaagc caagtgcatc ttcatggtct ggtgtgatga
     3061 tctcaatact tgcatcttcc tcgattggac gagtcaaatc aacgagtttt ccgttcactt
     3121 taccagctaa agcttttttt gctaagcttt ttgaaatgct ttcagcaatt gccaatgttg
     3181 ttgttccaga ctcaaattct ttgactgcac catctggaaa agtaattttt atcataatag
     3241 tttcctcctt gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa aaaaatccta
     3301 gcatctcttg aaaagagata ctaggacgaa aagttcgtgg ttccacctaa tgttcaaacg
     3361 caaatgcgtt cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca agggtttcga
     3421 aagtggtcat cctttggttt tctcctggaa aagtttcagc ctagcttttc ctctcttatc
     3481 gaagactctc aaattcagtt ggctttctca tcaatcaatt atgtgtttat ttaaccacta
     3541 ataaatagaa aaatcaagtg ggaaactaaa cttatttttt ccattcccca tttacaccgt
     3601 atgttccttt tttcatctca ttgatgatga catggatgtg ttcttttggt gcctgcgtgt
     3661 ttttatgaac agcttccgtg atatctttca tcatattttc taattgttcc ggactgcgac
     3721 cttctactaa ttcgacatgt acgaatggca taatgctctc tcctctttct gatcgttctt
     3781 ttttcaactc gattctatca tactatgttt gtcttgggta ctgaatcagg aaaaatggct
     3841 ggatcttttt ttgctctcaa ggcactcaaa atagagaccg tatccacgac ttcttgcaaa
     3901 acagctccga ataatgcggg gattagtccc gtacttgcaa ttaacatcaa aaaaatacaa
     3961 ataaagatgc caatcagtac agactgtttc gctattctca tcgtatctct tgaaatcact
     4021 actgcttttg ctacacgcaa gagatcatct ttcaagatga ccgcatctgc actttcacta
     4081 gcagctgtag aaccatgagc ccccattgca ataccgatat ctgcagcagc aagtgctggt
     4141 gcgtcattca cgccgtctcc taccatcgca acaggtcttt gatctttagg gatactttct
     4201 aaaatggtca gtttatcttg aggcaagcta cgggcatgta cagaatctaa ttggactttt
     4261 tctgcaatcg tttgagcaat ggcagatcca tccccggtga tcatcatcaa atttttcaca
     4321 tcaagttttc ttagctcctt gattgtcttt gctgcttctg ggcgaatctg atccgaaaat
     4381 aggatcgttc ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt ggacgtttct
     4441 atttcttcag ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt attgactact
     4501 gcttggattc cttgaccggt cacttctttc agttgactaa caggatacag ttggctgttt
     4561 ttcacgttgt tcactaacga acgagctaag atatggctag attcctgttc tgcactagct
     4621 gcatacagaa gtagctcttc tttttttatt ccattgactg gctgaatcgc ctctacttcc
     4681 aatatccctt tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt acgtgcgagc
     4741 ttttcaatcg ttgttccagt ttttacaacg atcccgtttt tacttgaacg gctcattcct
     4801 gcaactaaag caatgggcgc agctagaatc agtggacaag gtgatgccac taccagtacc
     4861 tcagcaaatc gtaaagggtc ttttgagaac caccaagaaa taccaccgat caaataagca
     4921 atcaacgtga aagggactgc ataacgatca gctaaacgga caaatcgggc aggcttttct
     4981 tttgattctt cgactagttt aataatcatt tgatactggc tgtctgcggc acgtttttca
     5041 gcgatcattt ggatcgatcc gtctccattt aaagaccctg acataatctg atctccaggt
     5101 ttcttggttt ccgggcggga ctcacctgtc aaagaagatt catcgaccga agattctcct
     5161 ttggtcactc gaccatctgc gggtacaagt tcgccaggct tgactagtaa ctggtcatca
     5221 atatttattt catcgattac tatatcctgc aattttcctt ctttgaatcg atgggcaatt
     5281 cttggggtgt tatctaacaa agactgcagt tctttacccg ctcgtttatt cgcgtaatcc
     5341 tctagactat ctccgcccgt aagcatgatc aatatcatca aactagccca gtattctttg
     5401 acggctaatg ttgcaaggat tgcggtaatc gctaatacat ctacgccata tcttcctgaa
     5461 cgtaacgtct tgatcatttc caaaaacatc aagaaggcga gaatccctcc agtaaatgcg
     5521 acaatcgcaa atgcaagggc cggctggtga aaaacaaatt cacttaataa agctatccca
     5581 ccaataagca aagtaagtaa aaattttttg aaatgtgtca ttgttttttc tcctctttta
     5641 tgtgacttag agaggttagt aataaatttc cagctgcctc tttcatctta agcatagtcc
     5701 ttgactagca ctttttaaaa caataggcct taattgaaaa caactatcac tatcagcgtt
     5761 tccaaaattc atcagttcta caaacaaaaa tattcagcaa ggattacttt ttcgattcat
     5821 cagttaaaaa gtaccttttt tcgaaaaact atgctatact tttaattcgt tatttacggc
     5881 ggaaggagca aacatgcgat gaatgagaaa caactagaac aaacgcacgt ggatgaaacg
     5941 atcgaactaa tccagatcga acaaaatatg ctggatacaa aacaacaaga attgactcag
     6001 gaaatgaatc attcgacaaa agacacagct aatcacaaga ttcgagctgg ttccaatgaa
     6061 gctttttatg aatctgctgt tgaatatcgc caacatgagc aggaattgct tttgaaatac
     6121 catactcttg aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa agatagtcct
     6181 tattttgccc gtatcgactt taaagaagac cgtgaaacag aaacattata tctaggtatc
     6241 gcttctttaa gagatctggc agaagaaaca atcgttattg actggcgcgc accaattgcc
     6301 aatctttatt atgaaggtga gattggtccc gcattttatg aaactgaaac agatagaata
     6361 gatgtcgatc tgcagttgaa acgacaattt aaaatccaag aaggacgtat tttatctatg
     6421 gtagatacgt cggaagtaat caatgatgac tttttgctag agatattgga tgaatcatca
     6481 agcaaccata tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc aatcattcgg
     6541 gacacaacaa gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa gacatccgct
     6601 ttgcttcaac gtattgcttt tctgttgtat cataatcgca agtggctcga ggctgaaaac
     6661 gttcttctat tttcacccaa ccatttgttt tctgattaca tctcgactgt attgccttca
     6721 ttaggtgaaa gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca gctgctgcca
     6781 gagttttctt tactagatga acagcaacaa gaaagtggtt ttttgctagg ggaaaaagat
     6841 ccgatacaag tgatgaaaag cggattgacc ttagtcgatc agattgatcg ctatatccaa
     6901 ggcatcacaa actacggtcc cttgttccgt gatatgaaaa taaatggccg tacgatccta
     6961 tcaaaggaat cgattcgcca atggtataaa gaaacaaatg aacaattacc tttacatcat
     7021 agactttctc tattacaaac gaagctcctg aaaaaattag gcggtctgca aaaagacgaa
     7081 acacgtcagc aatgggtcaa agatctggcg gaagaacagc tccaagaact atacgcaaca
     7141 gatccaaatc ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa actggccaac
     7201 caaatcgtac gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta tcaatttgtc
     7261 aatataacga aacaatatct ccactttcta caaactgtgc cactttctct tctaacacga
     7321 cataaaatca gcgagaccag gtggcaggaa catttgacaa ctgttcgtac acacttgcgt
     7381 caaagagaat tgcgtcaaga ggatgctgta ctattctttt tactgatgcg ccgaacatat
     7441 ccagtgacgg ttacacacaa agctcgctat atctttattg atgaaatgca ggatttcgca
     7501 ccatcacaag tggcattgct gcaagccttg ttcccaaaag caaatttgac tttctgtgga
     7561 gatctaaatc aaaatgtctt tggaaatgaa acgatcgttg gatcattgga agaccttttc
     7621 gtggaccgtg aagtcactcg tttccaatta acgacaagct atcgctccac aaaagaaatc
     7681 actgattttg ctaatcattt tattgtgaaa gaacatcaag tagaaacaac agcaagaaaa
     7741 ggagaccttc ctttgctcat ccaaggaaca acagatgata tcaaattgaa ttggttagca
     7801 gataccattc gaacgactca gggaaaagcc cggtattggc gtacagcaat catagctaaa
     7861 acacaagaag aatgcgaagc tctttatgct caactgccag acgagttgaa acaacaagtc
     7921 cagctgattt taaatgagag tgactttatg aagcgttcca ttattttact tccagccttt
     7981 ttagcaaaag gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc agaacatttt
     8041 tcttctcagc aagacaaatt gatcctttac accatgtgta cacgtgcgat gcatgaattg
     8101 acccttttta cctccaataa tgaaagtcct ttgttaaaca atatggatat ttcatcttat
     8161 gagaaaaaag tactgtaagt aaaaagacaa ctgctatcat taatgttagc agttgtcttt
     8221 ttatttacaa taataattgc agaaaaagta attcaatcat ttaaggtcat ttattctata
     8281 tataaatcca aatctgtttc aggatatttt aatttgacaa gcgaaataat cattttcagt
     8341 tcttccatgt tttctggata ttctgggtca aataccttgc tatgacggcc aatcccgcca
     8401 ttgtcgatca atcggtaaat tcgattccat tcaatgaatt ggtcaattga ttggaaattg
     8461 ctgattggat agccgccaca atccaaaatc tctgatacac gaaatgctag gtatgcacta
     8521 tcgatcactt tatttttttt cgtgtctatc ttctcatttc tttcgataag aattttttca
     8581 ggacgatgtt tcaagctcca ctctaatagt agaaagaaag cctccatccg atactcttct
     8641 tcaaataacc gaaaggctga atcagaacga cgaaaaagca gcggaatcag ataattttgt
     8701 ctataaatca gcattggtgc gcggtccacc atacactcta aataacggtt cagataccct
     8761 gtaccgacat agtttcctaa tcgatagcct tcaacgccga atcttgcgta tttttgcgct
     8821 aattttgaac aatcagttac gttcacagct aactcttcta ctttgcggta accgcttaag
     8881 atacgttcaa aaggttctaa agtgattttt gcttccatat tcttccccgt ccatcttcca
     8941 catacttcat atcatttcac atgatactta tgctctcatc ataccacagg ttgaattaga
     9001 aaagaaaata aatcacacaa aaaagcaaga caatctgtta gtgagattgt cttgcttttc
     9061 gaaaaagact gaatactttt cgttaaaact ggttgcttag tcttctaatg ccacattatg
     9121 gaacacatgc tgtacatctt ctagatcttc cagtgcatca atcatttttt caaatgtttc
     9181 ttgatcttct ggagatagtg ttacctcgtt ttgagggatc atttggatct cagcgattga
     9241 aaaatcagtg attccttttt cttttaatgc ttcttgtata ctatggaaat ccgctacttc
     9301 accgtaaacg atgatttgtc cttcttcttc cattacatcg cgaacatcga tgtctttttc
     9361 cattaggtat tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga ttgctgtatt
     9421 gtcaaacatg taagaaaccg ctccggaaac acccatgttc ccgccatttt tcccaaatgc
     9481 tgcccgtacg tctgctgctg ttcgattcac attgttcgtc aatgtatcaa caatcaccat
     9541 tgagccgctt ggtccaaatc cttcatagcg caattcagag tatgtttcat ctcctgcacc
     9601 ttttgctttt tcgattgctc ggtcaataat atgttttggt acattataag ttttagcgcg
     9661 atcaatgacg aaacgtagtt tttggtttgc atgcggatca ggatcacctg attttgctgc
     9721 cgcgtagatt tcaatcccaa attttgcata aatccggcta ttattagcat ctttagcagt
     9781 tttctttgct acgatatttg cccatttacg tcccatattt tcacttcgct ttctgatttg
     9841 atagtttcat aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg attctgtgaa
     9901 gctttttttc tttcttcctt cattcttctc atttttagtc aattatctat actcggattg
     9961 ggatttgccc gaaattctgt tccggaatat tgcctcccaa ttgatagatt tgatcacttc
    10021 taactaacag ttccgcttct tgtgcctctt tttttccgat tcgggaataa atagaaatct
    10081 cttttttttc ttttaagaat cttcttccag catcggtaaa tccaagtagt cgaagataat
    10141 ttttattttg ttggacagga atctcttgct ttttgatatt cagcaagaca taacaagata
    10201 atcgttggat ccgtgtccat gtatatcttt ttgtttttac ctttgacaca aaatcctcaa
    10261 aactatcagc agttgcagct gctgttttca tgcgcgattc tattccttcg gtcatctgat
    10321 agatatctgt cagttccagc aaagtagaag ataacaaccg ataacgcaaa tacggccaat
    10381 aagattccca agtctgcagc gaacaagttg aaagatcttc ttctgtctga ggcggcacaa
    10441 gtccagctat tctttttcct tcttctaacg catggcgaat ggctgttgca ctggctatcc
    10501 tctgatctgt gatgattttt tcatgatagc ctgcactttt acgtcggatc ggatgtaatt
    10561 ccatagggtg gacatacttg gcattttcct ttgcataact taatcccaag atatgatttg
    10621 gcgaagaaaa atcaagcgta atatcgggat acagactgcg aaaaacctca gtcatttttt
    10681 gcggataact atacgtttga tcagacagtt cttgaaatgc ctcttctatc ctatcttgat
    10741 tctcttggac aaagcgtccg aaactgctgt aatcaaacga agtctcttct tctgttccaa
    10801 aacacaaact gtcacagtcc agtgtttgca agatttttac tgcaccttta gcaaaatagt
    10861 cagctgactg aaccgcccat tcgacgggaa gctccactac taaatccaca ccattttgta
    10921 aagcttcatt cgcgcgatgc catttatcga tgatagccgg ttcgcctctt tgcaaaaaat
    10981 tcccgctcat tacagcaatg acgacctctg ctcctgttat ttttcgtgcc atttccacat
    11041 gatagcgatg tccattgtga aaaggattgt actctacgat aatcccgcag cttttcatgc
    11101 gcatcctcct tcatagttat cgataaaaaa gaaatagaga caagtaaaaa aaggcaaaaa
    11161 tcggaaaaaa tacccgaact atataaacta ttctcgcaaa cacaatactt ctgcgacgaa
    11221 aagctgcact gcaagagcaa tgcctatatc gttcggatat ataatttatg ttgaagattt
    11281 attcttttct tgttaactcg agcaggcaaa accgctagtc tttgtatgct acaaagaacc
    11341 agcgctttga tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct tcgactttcg
    11401 aaaagccgct gttttccagc attcttaaat aactttccaa tggataggta cgctcttgat
    11461 gtagttcatc ttcacgaata aatcgaccag acccttcttg ttcttcaacg aaaaaggtaa
    11521 gaaaatgttc gatgctgtgt ttctcgcttc ctggataact atcccacaaa aaagcaaaat
    11581 tatccccttg ataatgatag ctatattctg gaaaaacctc atctacttga taggtggagt
    11641 gtacgtcaaa taaaaatcgg ccattttctt ctaacgcttg atagacttca tcaaacactt
    11701 gctgtacctc ttgtctattt ttcatatagc acagcgaatc agaaaaacag gtaattgcct
    11761 gatattgtcc gatttctgat aaatcgagca tattgccttc cacaaattgg atcgatgcgt
    11821 cttcttcata tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg tctaaccctg
    11881 tcactttata tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg catgccagtt
    11941 ccaaaatatt ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac cattgctgat
    12001 aaagtgtttc gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa gccatatgtt
    12061 aatccaacca ttcactaaga tcgactagcg gagcatctga ccatagtttt tccagattat
    12121 agaaatttcg ttctggcgca tggaaaacat gtacgatcac atctccaaga tcgatcaata
    12181 cccattttcc gccttctttt ccttcaatac gttttacttc atatttgttt tcttcttctt
    12241 tatcaatgat ttcttctgta attgcgttga tttgacgttc gctatttgct gaacagatca
    12301 tgaaataatc tgccaacaag gaaacatttc gaacgtctaa agcgataatg tcttctgccc
    12361 gttttgaatc tgctgcttca atcgcaattt ttaattgttc tttactatct atgatgattt
    12421 cctcctaata tgagcagctt atttttttgc tacccagtaa ttatatgttt cgattgtttt
    12481 tggataaatc tgttgttctt gcgcaagcaa atgggccaat gtatgttttg tttcaaatgc
    12541 tacagcttcg tctagatcag cccatgcaat ggctcgtgca tcttgtaccc caggaaaatc
    12601 tcgacctggt tcaatatagt ctgctacata aatgattttg tcaaggagac tcatcttagc
    12661 agccccagtc gtatgcaccc ggattgcatg aagaatctct gcatcggtga ttcctaattc
    12721 ccgctctaca aacgaagcgc caacaagacc atgccagatt gcattattat aattcaataa
    12781 ctccggatca aaaccgtctc ttacgattac cattttgaac tcctcatctg gtcgttcttt
    12841 tgcataatca tgtgtcaatg cagcaatact agctttttca ggagaagcac cgtatttttt
    12901 ggcaagagcc acggctgttt cttctactcc aagcacatgc ttgaagcgtt gttcgctcat
    12961 tctcatctgt attttttgca tcaggttttc tctagaataa gcagtatatt cattactata
    13021 gtccatattc atacaaccct tcattttgaa tataatcaat tactttatct ggaacaaggt
    13081 agcggataga acagccttct ttgatctttt gacgtatttt cgtggaactg atgtcgatct
    13141 caggtacatc tacccaaatt acaggatatg gagtatccgt tgtgtatcct ggtcgacgta
    13201 tacccacaaa gttgaccata gaagtcagct catcgatttt ataccatttt ggcaaatatt
    13261 ctaccatatc cccaccgata ataaagtaat aatctgtatc cggattgttt tgcgtcaatt
    13321 ccttcatagt atcataggtg taacttttcc caccacgagc taattcaatc gtttcaatct
    13381 gcaaaaaagg attgtcttcc accgctaatt ccaacatgtt gagtcgatgt tttgcatcaa
    13441 tcgtctgttt ctcatcaaca tgaggtggct gataagaagg catcaaaaat acgcggtcaa
    13501 gacctaaatt ccggccagct tgttcagcca tcactaaatg tgcaaggtga acgggattga
    13561 atgttccgcc caagatccct acttgctttt tcttctctaa gaattgaggc atttcttcag
    13621 gaaataattg tgaacgaaca aatgtcttag cttgcgtatt catcatggtc actccttata
    13681 ttgcttttac ttcttttgat agcctttgat acttttcttt tgtggaaggt ttgtataata
    13741 caataacacg tccaatgatt tggacgattt cgcaatctat ttctttttct aatacttgag
    13801 ctgcttcttc tgcaatctca tctgtatttt gaagtaacga tactttgatc agttctcttt
    13861 tttctaaagc ttcttcaatt tgaacgatca ttgctgaatt gatcccacct tttccgattt
    13921 gaaaaatcgg ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt tttcctctta
    13981 aactcataat tttccttctt ccttaaatca atgctttgcg tttcaataca tctacaccct
    14041 ttggcgccca gcccgcaatt actactggcg ctgttacagt gatccagcct agaccggcaa
    14101 aaacgatgtc tgttttttct ttcacagaaa actcaaaacg aacaagctcc ggaaatgcct
    14161 cgacttcatc aggacgagga ggctgtaata atccacctac atgtttttga taaaattcgt
    14221 ctgctttttc cagtttcgtc cgatgaatat ttacatcatt tgacacataa gcaataaatg
    14281 aagcacgatt gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa agtgtttgcc
    14341 cttcattcag ctgataaact ttaggtttga tttcttttaa cggtgcaatg atccgcaaat
    14401 cttttttacc taagtagtgc gccatttgat ggcgatggat aattcccggt gtatcaatca
    14461 aaaaatgccc gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct ggaaactgcg
    14521 aagttgtgat tacatcttgt actcccgctg tatttttgat gatttgattg ataagcgtcg
    14581 attttccgac atttgttact ccgacgatat agacatcccg tccatcgcgg tattcttcga
    14641 ttttttctaa tagttccgtc atctcatgag atttcttagc actagttaat aatacatcta
    14701 ctggacgaat tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat ttagtttttt
    14761 tcaatgattt aggtaatata tccactttgt tcccaactaa aagtactgga ttgtcaccga
    14821 caaaacggtg tagtcctggg attagtgaac cattgaagtc aaaaatatcc accacattga
    14881 cgatcaatgc atctttttgc cctaattcat tcagtaagcg caaaaagtcg tcatccgtca
    14941 atgagacatc ttgggtctca ttataatggc gtaatctgaa acaacgctga caatagactt
    15001 ccccggaagc taaacctttt tccaaagccg tttgcggcgt gtatcctaat tcaccgggtt
    15061 tgtttgtttg tataacggca ccacagccga tacattgtaa ttcttctgtc attcgattcc
    15121 acctcgccag cccatatcag ggtgttttgc taatagatag gccataattc ttttttccca
    15181 aaaacgatta aattgtgtct tccaactatc tgttgcgata atgggtttta caaggatgct
    15241 acgtatccct gcacgattgg ctccacgtat atcagtcata atctgatcgc ctaccattac
    15301 tatctcatca tctgctaaat ccaattgttt ctttgctatg ttgatccctc ttgctaaagg
    15361 tttcattgct cgtgcaacat acaaaagatc aaatttttca atcgctcgcg cgacacgttt
    15421 tgaattattg tttgaaacaa caacaacagg gattcctgca tttttcattt ctaaaatcca
    15481 agtaagcaac tcttctgttc catctggatt attccatgca atcaacgtat tgtctaaatc
    15541 ggtcaatact gctttgatgc ctagattctt taattgggca ggtgtaatct gatagatggc
    15601 ttctaccatc catgttggtt tgtaatttga aaacatgctg tctcctcatc tgcaaaaaat
    15661 gaaggagcac ataaagtact cctcaacccc gtattatact gcatatcagc aaaaaaaact
    15721 acctctatac tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac caaaaataaa
    15781 gattgatcac agaaaaattt agaaacaaaa aacaactaat attggcggaa cctcttgtat
    15841 cgtttttcca gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct ttcaatcaac
    15901 gcttttttca taatgtgtgc gactttatat cgtggcaact gctcgccgtt gaacgtttca
    15961 ggaataactc gatcaacgat tcctaactcg cgtagttctg gcgcagtaat tttcatcaac
    16021 tcagctgctt ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa tccttctgga
    16081 gaaagcacag cataaatcgt ttcttccagc atccagactt catccgctaa acctagagca
    16141 agggcaccgc cacttccacc ttcaccaatg atgatggcga tgatcggtac ctttaaatca
    16201 gacatttcga gcagatttct ggcaatagcc tctccttcgc cgcgctcttc tgctcctaca
    16261 ccgcaatatg cacctgctgt attgatcaag gtaatcaccg gtctattgaa cttttccgct
    16321 tgtttcatca gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc aaaatttctg
    16381 cggatatttt cctgcagatc ccgtcctttt tgaataccga tcactgttac cggtttgcca
    16441 tctaatcgag cgattccacc aacaatcgct tcgtcatctg caaataaacg atcaccatgg
    16501 cattcctcga aagaatcgaa gatctcttca aaaaaatcca agcttgtcca tcgttcttta
    16561 gctcttgcta actgaacgac atcatgtgct gtcttatcca cgatctatcc atcctttctg
    16621 tgtatgcaat tcaagaagcg tatggatttt ctgtttcaat tccatgcggg gaacaatctg
    16681 atcgacaaaa ccatgagata ataagaattc agccttttgg aaatcttctg gaagttcctg
    16741 cttgatcgtc tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt ggggttctgc
    16801 tagaataata tcgccttcca ttgcaaaact ggcagttact cctccggtcg tcgggtccgt
    16861 taaaacagtt agataaaaaa gaccttcatt gctatgccgt ttgacagcag cagagatttt
    16921 tgccatctgc attagagaaa agattccttc ttgcatccgt gcgccacctg aagctgtgaa
    16981 caagacgact ggaagacttt cctttgttgc tcgttcgaat aatctggtga tcttttctcc
    17041 gacaatcgtt cccatacttc ccatgataaa attaggatcc atcactccaa taatgaaggg
    17101 aatcccctga atggttgctt taccagtgag gactgcttca tgaagtcctg ttttatcttg
    17161 cattttttta attttttccg tatattcggg aaatgctagc ggatctttgg ttacaagatc
    17221 cgtatcccat tcttcaaaac ttttttcatc aataatcaaa gctagacgct gccatgcacc
    17281 gattcgaaaa gcgtatccgc aatgagggca tactttttct tcaccgatgt ctttcgtata
    17341 aaggatatgt ttgcaatttg gacactttgc ccacatgtta tcaggaacag atggcgagtt
    17401 agcaggtttg ctctctctat taggattgat ccgaatatat ttctttttct taaacagagc
    17461 catctatgcg cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt cttcttgtaa
    17521 aaatgctgtg ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat ccatctgaaa
    17581 ttctgcgttc gtgatgattc cttctgtgat aaattcactt aaggctcgct gcatcttcat
    17641 taatgcttca aaacgcgtat ttccatggac gattattttt gcaatcattg aatcataata
    17701 tggcgggatc gtatatcccg ggtaaactgc actgtctact cgcagtccca tcccacctgc
    17761 tggaagcagt aagttttgga tcttccctgg agaaggagca aaatggaaag caggattttc
    17821 tgcattaatc cggcattcga ttgcgtgtcc ttggaatact acttcttctt gacacacatt
    17881 caaaggctca ccggctgcta tctccacctg tttttttact aaatcgattc ctgtgaccat
    17941 ttctgttact ggatgttcca cttggattcg agtattcatt tccatgaaat aaaaatcgcc
    18001 ttcttcatcc atcagaaact cgatcgttcc ggcattttca taattgactg ctttagctgc
    18061 tcgaacagca gcgtctccta gtgcttctct ttttgtttgt gagatcacta cagaaggaga
    18121 ttcttccagt actttttgat tgttgcgttg taaagaacaa tctcgctcgc ctaaatgaat
    18181 gacatgacca aatcgatcac ctaagatctg aacttctata tggcgagcag gataaatgat
    18241 tttttccaaa tacatatcat catttccaaa tgccgctgct gcttcttgct gagctgaaga
    18301 aaaatgctgt gggagctctt cttttgattg aactttccga atgcctttcc cgccaccacc
    18361 tgcagctgct ttcagcatca ctggataacc aattctgtct gctatttcca atgcttcttc
    18421 tactgtagat aatacaccag tacttcctgg aatgactggg acatttgctt cttgcatcaa
    18481 ttgacgcgca ttgatcttat ttcccattgc atcgatcgtt gcacttttag gaccaataaa
    18541 tgtgatattg cactcttcac acatggaggc aaatcggcta ttttcagata aaaaaccaaa
    18601 tcctggatga attgcttcgg cttttgtcac gattgcagcg ctcagtactt cctgaacatt
    18661 cagatatgaa tcaacggctt ttgccgggcc aatgcagatt gcttcatctg ctaactgtgt
    18721 atgaagtgct tcggcatctg cttctgaata tatcgctacg gtttggatcc ctagttcgcg
    18781 gcatgcacga atgatacgta cagcgatttc accgcggtta gctatcaata ctttagaaaa
    18841 catatttcac ctatccaatc ataaaggtta attccgcttc ggctactttt ttaccgtcta
    18901 ctttagcgat tcctttgcct attccggctg aagctttcac tttcaatatc tcaacttcaa
    18961 ggtataaggt atctcccggt gtaactttct tacggaattt tgctttgtcc aatccgccga
    19021 aataagccgt ctttcccttg aattgttcaa gagaaagtaa tgcaactgct cctgcttgag
    19081 ccattgcttc aacaatcaat acccctggca taacaggttc ttctggaaaa tgtccttgaa
    19141 aaaagggctc attgatcgtt acatttttct tagcaacgat ccgttctcct tcaaccattt
    19201 cttccactcg atcaatcaaa agcattggat aacgatgtgg aatgatttct tttatttctt
    19261 gtatgttcat tgttttccct ctttcctgct ttgcttattt ttgctgaatc ctaaagagtg
    19321 gctgtccata ttcgacaact gactcgtttt ctacaaggat ttctgtgatc actccgtcgg
    19381 cctcactagt tatctcattc atcagtttca tcgcttcaat aatgcagata acttctcctt
    19441 tggcaacttg atcacctact tttttgaaag ctggtttgtc gggcgctggt tgcagataaa
    19501 cgattcccac gattggcgaa acaacctcga ttccatcaaa tactgccgat tctttttctt
    19561 tcattatttc tggagcagtt gttgcttgtt caggtatgac attgactggc tccgaaactg
    19621 gcaacgtttc gtttgtttga accatattca tgcctcgact tgttttattt ttattcatat
    19681 acaattcaaa ttgaccttca cgcaaatcga attccgttag cgaggattga tcaaattgac
    19741 tgactaattc tctgatttca ttgatatcca aaattattcc tcccagcgtt tcatgcacag
    19801 aaccgcatta tgtccgccaa accctaatga attactcatt gcataagtaa aacttgcagg
    19861 tttgctttcg tttttgacaa ctgtcaagtc aatctcagga tcttgttttt ctacattgat
    19921 cgtaggtggg ataaattgat gttctaatgc cagcaaagtt gccaaggctt cgatcccgcc
    19981 ggctgctccc aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag tatctctgaa
    20041 attttcacct aatgcgattt ggattgcttt tgcttctgcc tggtcattgg ctggtgtact
    20101 tgttccgtga gcattgatat atccgacttg ttccggctgt acaccagctt cttccatcgc
    20161 aagcttcatt gctttagatg caccagaacc atctggagta ggagctgtca tatggtaagc
    20221 gtcacagttt gcaccgtatc caacgatttc tccatagatt ttggcaccgc gagcttgtgc
    20281 atgttctaaa gattcaagaa ctagaacgcc tgctccttca cccatcacaa aaccattccg
    20341 attttcgtca aacggaatcg aaccacgatt aggatcagtt gattctgaga gtgctgttaa
    20401 agctgcaaat ccagcaatcc ccatctcaca aatcgttgct tctgttcctc cagcaagaat
    20461 gacatcagaa tagccatgtt tgatgttacg gaatgcttcc ccaattgaat tcgttccgct
    20521 agcacaagct gttacgatag ctgtacaaat accttttgca cctacacgca aagcaatatt
    20581 tccagctgcc atgttggcaa tcgccattgg tacgaacatt ggagaaactc gttttgcacc
    20641 tttttcatgt agacgaataa cttggttttc gattgttgga agaccaccga tcccagatcc
    20701 gatgatgacg ccaaaccggt cttgattcat tttttcttta tctaaaccgc tcatctccat
    20761 tgcttctaaa gcagcgtaga ttccatagat cgaaaacata tccattcgtt tgctatcttt
    20821 tttaataaaa tatttatcgt aagggaaatc tttgacttca cccgctaagg taatccctgt
    20881 ttctgaagca tcaaatttag tgatcggtgc gatgccattc gtcccctctt ttaagctatt
    20941 caaaaagctg tctgcgtcat ttccaatagg tgaagtgact ccatagccag taattaccac
    21001 tcgattcatt tgtttgctct ccttttctta tccgtgcatg accaatccgc catcgacatt
    21061 gatgacttgt ccggtgatat atggattttg tgctaagaaa actgctgttt gtgcaatatc
    21121 ttctacttgt ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct tgactttgtc
    21181 tgctaaaact tccgtcatat cagttgtgat gaatcctggc gcaatggcat tacatgtaat
    21241 gcctctagtt gcagcttctc gtgccacaga ttttgttaat cctactacgc cagctttact
    21301 agctgcataa tttgcttgac caatatttcc aatcaaccca gatacactag agagattaat
    21361 gatggcccct tctcgctgct tcatcatttt tttcaatacg tgctgcgtca tattgaaggt
    21421 tccaatcaaa ttgatatcca gacatttttt gaaatcttct gcatccattc gcatcacaag
    21481 tttgtcattt gtgattccgg cattgtttac taacacatgg atcgatccaa gcttttcttc
    21541 tgcttctttg atcatttgtc ccgctttctc ataatcagag atgtcaccgg aaactcctac
    21601 gcattttaca ccgaatgctt cgatttcttc tatcttttct tttggaatct ctccgcgacc
    21661 attcaaaatg atatttgctc cagcttttgc aaaagctaag gccatcgctt tgccgattcc
    21721 tcttgtacta cctgtgataa atacattttt tccttttaca tccataacgt tcctccttat
    21781 agtattgcta ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac tggtattgtt
    21841 ttatcgattt ttttcataaa tccgcttaat acttttccgg ggccgacttc gatgacttgt
    21901 tcgatgccga ttgtttttaa cttatggata ctctcataga aacgaacagg ttgcatgact
    21961 tgctgttcaa gtagtcccgc gattgtttct ttcttcatta tttccgttgt tgtgttgctt
    22021 atgataggaa aagaaggttc agagaattga atctgactta ggtccttcgc cagttttttt
    22081 gctgccggtt ctaaaatagc tgtatgaaaa ggcccgctga catttagagg gatcattctt
    22141 ttgaaccctt tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc ttcgccacca
    22201 atcacgatct gctgaggtgt attataattt gcaggagata cgatgccgta cttgctagct
    22261 tcatgacagc tttcctcgat cgtttcaatc ggcgcattca tcactgcaac cattttcccg
    22321 cttccagctg gggcagcttc tgtcatataa gcgcctcttt ttgctactaa cgcaactgct
    22381 tcagtgaagg atagcgcatt actagctact aatgccgaat attctcctaa actcagtcct
    22441 aaagctgcat ctgggatgat tccatgctcc ttcaataagc gataatacgc gatgctgact
    22501 gttagaatag ctggctgtgt atattgcgtc tgatccaaac gttcattttc tgtaaagcaa
    22561 agttcagcca tatcgtagcc gagaatctca cttgcttcat caaatgtctg ctttacaacg
    22621 gcttcttcat ataaatcttt tcccatacct tgatattgtg caccttggcc actaaataag
    22681 aatgctgttt tcatgttttt ctccaatata tccagaatat atgtttgatt cttcctattc
    22741 aaaaaggccg agacattcct atttcaggaa atgtcccagc ccccaaccta attttaatga
    22801 ttatgcagtt tgtttttcta cgtaagtcac taaatcttga accgttttga ttccgtcttc
    22861 tgtttcgatt ttcacgtcaa attcatcttc aatttcattg atgatttgga ataaatccaa
    22921 gctgtcagct tctaagtctt cttggatgtc agtagtcaat ttgatttctt cagtttcttt
    22981 tcctaattct tctgcgatga tttcttgaat tttttcgaat accataataa tatattcctc
    23041 cgatattgtt tgctttttat ttttataatt taacagtcta caactccatg agaatacttc
    23101 cccatgttaa acctccgcca tagcctgtaa atattacttt ctgctgtttt cctaaggtga
    23161 tctttccact agaaactgct tcatccaata agatagggat gcttgcagca gatgtattcc
    23221 catatttatc catattggtc aggaactttt cttgcggcat ctttactttt cgggcaattt
    23281 tctcaataat tctgaggttt gcctgatgca aaagcagata atcaactggt ttgtctttca
    23341 tgacttcttg gatattgttt gcaacgtctc gtacggcaaa atcaaaaata tctctgccag
    23401 tcatttgcaa ataatacgaa ccttctgaat cttctgaata gaacggattt ttattttgct
    23461 ggtagccagc ggtcaatgag ctacttctgg taccgtcagc tgctaatttt tctttcagca
    23521 attttttctg tggattcgct tctaagagaa tcccacctgc tccatcgcca aacaacacag
    23581 cagtcgtacg atcagaccaa tcgattagct tagatagtgt ttcaccacca atcaccagtc
    23641 ccttagttga gccgcagcgg atcatttttt cagccatgct taacgcataa acaaatcctg
    23701 agcacgcagc actgatatca aaagcgatag catgagttgc tcccaatttc ccttgtactt
    23761 gtgctgctac agatggtgtc gtgtaatcgg gcgacattgt tgctactaaa ataaaatcca
    23821 aatctttagg gtttagattt ttctgtttta tcaatttttc cgccactaaa atgcataaat
    23881 cagaagtctc ctgatttgtt acacatcttc gttcacgaat acccgtcctt gacgaaatcc
    23941 attcatcaga ggtatccatc atcttggaaa gatcattatt agtaataatc ttttcaggaa
    24001 ggacgctggc tgttgcagta atcattccaa attgttccat taaatatcct cacttatagt
    24061 cttgcaagaa gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt tcctccgtag
    24121 ccattccgtc taagatgttc ttgaccattt cacgatgaaa atgctgatgg acccgaaata
    24181 gtaactttcc ttttttcgtt agtcccaact ttacaacgcg gcggtcatct tcactgcgga
    24241 tacgttcgac atagcctttt tttactaact tgttaatagc agtggtcaag gtcccaacag
    24301 taattgatag ttctttggct acttctgaag ttgttttttt cttgtacatc ccgattgcct
    24361 cgatcgtgtg catctctgtg attgacagat ctttgaattg agattttttc agctcagact
    24421 cttcgattgt caaaatatca ttgaagacac taacaagata atcatttact gtttttaaat
    24481 ctggttccat gttccaccgt ccactaatta gtttgattat caaatctttt gatgttcaaa
    24541 ctatatctta acttttttca aaatgcaacc ttaaaagatc atttttttac tatatgagct
    24601 ttttttaaga ttttactcat ttaaaacaac tgataaatca gcatttataa tttcttttat
    24661 tagaaaaatc atctatctca catattttga ttatcaaagt attttctgtg aacagaacta
    24721 tagaattccc taaaacttgt ccattatttc aaaatttgtt atagtctttt tattcaaagc
    24781 gtaaaaggag atcctatgtt aaaagaaaaa atgaaaactc tccccatgct gccgggtgtc
    24841 tatcttatga aagaccgaga tggtaaggtc atctatgttg gtaaagcaaa acggctcaaa
    24901 aatagagtaa gcagctattt tcatcagaat aaacagcatt caaaaaaagt attacgtatg
    24961 attcatcata taacagattt tgatttcgtc gtagtagaca cggaattaga tgctttattg
    25021 ctcgagtgtc aattgatcca acattaccgt cctttttata accgacaaat gaattatttc
    25081 agtaattata attatgtaca tattaccaat aagggatttg tattaacaga tactcctacg
    25141 gctcgaacat acgggccttt tcgtctctat aaaaaaatgc cgtctatttt gcgtataatg
    25201 gaagaaactt atcaaatgcc ttggttgtct gaaattagtt tgttagcttt gcgagtccag
    25261 cttcctgacc tacaggaaat gacttttgaa cagaaaaaaa aggaactcca agggctgttt
    25321 caaggccgaa ataaaaagct actgacttac ttgaaaaaaa gacaacaaca tttcatctat
    25381 cagttgaatt tcgaaaaagc cggtatgctt caaaaagata tcgaattagt tacttatttt
    25441 attagacgga tccaggaaca aaagcagttt ttaagaacac catcgctcac cttcagcatg
    25501 ccattagcag cagatgagag tcagaaaaag cactacctcg tttgttatgg tcaacttgca
    25561 gaaacaatga ttacctctgg tgacgtttct cctgacttct attatgaaaa gaaagaagct
    25621 catttatctt tgaaacgtca attgtcaaaa gaagaaatcg atcctgtaca aatcttgatc
    25681 agttaccgca aaaaattaga aaaagaacag tttgaaattg aactgttaaa caaaaaagaa
    25741 gctgaaaagc aactaaatta gttgcttctc ggcttctttt aggcatcttc aacttcaaat
    25801 gtcaattatc ctaaaattta ttggattaag tcatagattt ccatcgctac gatatcgata
    25861 ttatcaaatt cgtattgctg atgagtatct gtttcagtta attcaaatgt atcggtcgct
    25921 ttatcataag ttactgtaca cttctctacg ccttcttttt caaaacggcg aacttgcagt
    25981 tcattatctg ctgactcgac catagcctcc agtcgtttta tgattgcgac taattgtgaa
    26041 tgtgtcatcg gaggtcctcc ttttcttatt tctgttatat tgtatcaaaa gcatagccta
    26101 cttgcattga ttttctctaa aaaaactcgt tttttatgat tttttttctg gtatttttcc
    26161 ttcaggccac caaagtttga tcaaagcttg ggttccgtca ttctcaaaac ctttatctgc
    26221 caactcttca tatagtttca atgcttgggt agttgctggc aatacaagat ccattttttc
    26281 tgcttcttct aatgcaatct ttaaatcttt gataaaatgt ttgacaaaaa aaccaggtgt
    26341 gtaatcttct tttaaaatac gaggagaata attgcttaaa gaccagttag ctgcacttcc
    26401 acctgaaagc gtctcaatca ctttctttaa atcaagtccg tttttttgtg catagacaag
    26461 catttccgtc attcctgtca tcgtacctgc aatcatgatc tgattagcca tttttgtatg
    26521 ctgacctttc ccagcagaac catgcaatgt aaatgtcgta ccaaattctt tgaataaagg
    26581 cagtacttga tcataaacgg cttcttctcc accgaccatg atcgtcagtg taccattctt
    26641 tgctcctaag tcaccaccgg ataccggtgc atctaacgca tctgcgcctt tttcttttgc
    26701 tgtttttgca attttttctg ccaggcttgg tgtacttgta gtcaaatcaa ctaaaatatg
    26761 tcctgagata tctgcagaaa aaatccccga ctgtccatag tagatttctt ctacatcttt
    26821 ggggtaacct accattgtaa agagaatatt actttgttct gctaccgctt ttggtgtatc
    26881 tgcccagata gctccttctg ttactaaagg atcagctttt gcttttgtcc gattatagac
    26941 agctacttcg tgtcctgctt ctagtagatg gcgtgcgaca gcacttccca tgacgcctgt
    27001 tccgataaaa ccaagtttca ttttttcgac ctcctaaaaa tcaaaaatcc ttgcttctat
    27061 gctagtatac gctagaaaca aggatttttt cataaaaaat gtttgaattt tatcttttaa
    27121 atgaatttaa ttttattttg attcgttcaa tcgagtcttc ttcttctttt cttcgcatct
    27181 cttcttcatg ataaacaacc atgtcttgat aaaattcgat catagcttcg ccgaaatgtg
    27241 tagatgaaat atcataaagt ttagcttcta aaacttttgg atctttagga acttcactgg
    27301 aaatataatc aataagtgct ggtgcaaagt cttcgtcggt ttcaaaagtt ttccctaatg
    27361 aaggatgatc gaacaatcgg ttcaaataag catttccttc cacgacacaa ggtgttccgg
    27421 ctgccatcgc ttctgtataa gtaagccctt gtgtttctga agtagaagca ctgacaaaat
    27481 aatctgccgc tttataataa agtgctacat cattgttgtc cacttctcct gtgaactgca
    27541 caaattcttc taactgcagt tctgagatca attcctctaa ctcttctaca taaggtcctt
    27601 ttcctacgat aactaatctg gcgttaggat aagcggagat gacctgagga aacccattaa
    27661 tcaaggcttg gatatttttc tcataagaaa tcctgcttaa agaaagaatc atcaaatggt
    27721 tttcctgaag acctagtgac tcccttaatt tgctgatatc ctgctgagtg atatcagaac
    27781 gtttgaattt ttcaatgtcg ataccagtag gaatcacgcg aagcggtgct attacaccat
    27841 agctgcgtaa tgtatcaata acacgttcac ttggacaaac tacacctgtc gtatgatttg
    27901 caaataatct agacaagtat tttacatggg attgcctgat cacttttcct ttaccgatat
    27961 aatgaaggta gtcttcatac atcgtatggt aagtatggat cagaggtatt ttcaacttct
    28021 tagctaccat cttcccaagt atccctgctc cgaattctgt atgggtatga ataagatcta
    28081 gttctagttc tttggcaacc aaataagcat accacatgcc tctaacaaca actcttcgat
    28141 ccttgaaaga aataaatggt acacttggca ttcgaatcac atctttttcc aacttatccg
    28201 cattaggatc ggtcgttgta aaaatataga cttcatgccc atgtctttct aattcttgtt
    28261 ttaatgtttt gatcgatgta gcaactccgc tgacttgcgg aaagtaggta tcggtaaaaa
    28321 agccgatttt catgtttttc gcctccaaac tagtccttga cctgatttac tttttttaat
    28381 ttgctagaga ctttttcatt cagtacactt tcgtatacat ttttaagttc ttcaccgatt
    28441 ttattgatac ttcgctcttt tgctgtttga taaccggctt gtgtcgtact cggtagttct
    28501 tgattggtaa tctgttggat cagtcggata aattcttcgt ttgtcttccc catatagcag
    28561 ttcttgctat cttctaacca gccattatac actggaatat ctcgaacaag tacgttttgt
    28621 ttgcttgcta aagcttctaa aacaacgatc ccttctgtct cttcataaga agggaaaaag
    28681 aatagatctg cacctgaata cgcaccttct atgatctctc cacgaatgta accaggaaac
    28741 aggacatttt caggatgatc ttcttttaca attttccgga tgttccgagg aatcgagtac
    28801 atgggaacat gaccaaacca aataaatgtg tattcgggca tcttcttagc aatttctacg
    28861 aaatcaatga ttcctttacg ttcgaaaaac aaaccgacac aaatgattac tttttgatcc
    28921 ggagacagtt tgaaatattc tctgaacttt tgttctttca ttggatcagg gtgatatttc
    28981 tctaagtcga tcccattgga aatagcttga atcggcacac ggataccata gctttccaac
    29041 aactgttttg aataaggtgt tggcgtgatc agatagtccg ctttttggta caatcctacc
    29101 agatattttt ttacgatagg agaaagctgg ttcgatctga taaaggaatt tcggaaatct
    29161 tcctctgtag aatgcgcatg atagacaact ttttttcctt ctcttctggc tttattgacc
    29221 atattatgac tattgattcc gtatgtattg atgtgcagga tgtcataatc ttctttttca
    29281 tctagtgtat aagagatacc gacttccgtc agagcacgtt tttgatgatc aagcgcacgc
    29341 ccgattccag attttgcaag catcttttca ctttcaaaat ataataatac cttcacctta
    29401 cgtccccctt cacttatata gtataacata gcctacaaac tgtcactcaa acttaagccc
    29461 tatttttgtc tattcttact gacaaaaacg ttttcttaaa aaagaacaaa aaaactggcg
    29521 tagctctttt acaagccaca ccagcttttg atacgttgtt tattttacat attcatgaac
    29581 aagttcaacg acttcttcca tcatatcgca ttctttcaat gcacgatcag caagttcagc
    29641 cattttcgct gtgtccaagc gtttcattaa actacgcgtt ttaagaatag atgtcgcact
    29701 cattgagaac tcatctagac ccatacctac tagcaatgga acagctgttt gatctccagc
    29761 catttctcca cacatacctg cccattttcc ttcagcgtgt gctgcatcaa ttacattttt
    29821 gatcaaacgt aaaattgatg ggttatatgg ttggtacaag taagaaacgc gttcgttcat
    29881 acggtctgct gccattgtgt attgaatcaa atcgttcgta cctacagaga agaaatctac
    29941 ttcttttgca aacttgtctg ctaagactgc tgctgctgga atctcgatca tgatgccgac
    30001 ttggatcgta tcagatactt ccttgccttc acttatcaat ttttgttttt cttcttcaaa
    30061 gatcgctttt gctgcgcgga attctttgag tgtagctacc atagggaaca tgatacgtaa
    30121 attaccatga acagatgcac gaagcaatgc acgcatttgt gtacggaaca tttcgtcgcc
    30181 ttgttcagat aaactgatac gcaatgcacg atatcctaag aatggattca tttcatgagg
    30241 taattgcaga tatggtagtt ctttatctcc accgatgtcc attgtacgaa caactacagg
    30301 ttttccttcc ataccttcta atacagcttt gtaagcttca tattggtcat cttctgttgg
    30361 gaagtctgga gaatccatat acaggaattc agtacggtac agaccaactg cttctccacc
    30421 attattatgg acaccaacta gatcttttgg tgttccgatg tttgcagcta attcaaaatg
    30481 cttgccgtca gctgtgacag tttctgcatt ttttaatttt tcccattctg ctttttgtgc
    30541 tgcgtaatct gcacctgctt tttcaaattc agctttttgt tcatctgtag gatcgatgat
    30601 tacatcgcct tcgatcccgt tgacagccaa aatatcgcct tctttgactt tagcagtaat
    30661 ttcttttgtc ccaacgattg ctggaatttc taaagaacgt gccatgatag cagaatgtga
    30721 agtacgtcca ccaatgtctg ttacaaacgc ttttacaaaa ttgcgatcta attgtgctgt
    30781 atcacttgga gtcaagtcat gtgcaacaac gaccacttct tcgttgatca ttgatggatt
    30841 tggtaaagta acgcctaata agtgcgctaa aatacgttta gcaacgtcac gaatatctgc
    30901 agcacgctct tgcatataag cattatcttc cattgcttcg aacataccga tatacatatc
    30961 cgttacttct tttagcgctg attcagcatt tacgctgttg tctttaatat tttgcttgat
    31021 ttgacctacc atttctggat ctgaaagaac catcaaatgg gcatcaaata cttgcgcttc
    31081 tgcttcacct aagctttgcg ctgctttttc acgaatttgc tgcaattctt cagtagattt
    31141 agctaatgca gcatccaaac gagcttcttc agccgcagta tcttctactg ttgccttact
    31201 gaatgttaaa tccggttgaa ctagcaggta agcttttgca acggctacac cgtcactagc
    31261 ggcaatccct tttagcattt caaccattat tcagataagc cttctttctt cattgtttca
    31321 acgattgctg ccattgcatc agcttcgtca gcaccttctg cagtaatagt aacatcagaa
    31381 ccttgaccta cacctaaaga cataacgccc atgattgatt tcaagtttac tgatttacct
    31441 ttatactcta agtttacatc agagttaaat ttgcttgctg tttgtactaa tagtgtagct
    31501 ggacgagcgt ggatcccagt ttctgctact acgtgaaatt ctttcttttc catattaatc
    31561 ggtctccttt aagtgagtgt tgtttttatg tgagggtttt cttttttagt aattcagaga
    31621 atcctaacaa atgccaccct ttcatctgta aagattaaca ttttttttcg ttagatacaa
    31681 cagttttcat tcaatttcag ataaaagtat tcaaattatt ccggattctt tttcatcctt
    31741 ttcttcacat tttataacaa acgtgtttat ttcctttttc ttgtcgcttt ctcttctcct
    31801 gacgtttatc attctttcct ttgaccctct ttgttttcat atgaaacgaa ttacttgctt
    31861 ccctttttat ttttagtata ataagagtca aaggtcagga atggtcaata gagatttcac
    31921 cttttctacc tcataaatct cttaaaaaac taggggttat tcttttacct catgaaaaac
    31981 gagatgtaaa atatggatgt acccattttt gtgaaaggac gtgaatgatt catgctttgt
    32041 caaaactgcg gcaagaatga ggcaacgatt cacttgtatg ccactgtcaa tggtcagcgg
    32101 acacaactcg attactgtca gagctgttat caaaaaatca aaaatcaaca aaatggaggt
    32161 ctgactaata tggcccaaaa tgatccattt ggatttggca gtttggacga tcttttccgt
    32221 tccatgtctc gccaaatgca acagcaagga aattatgagc aaacaccacc aacacaattt
    32281 ggcggaaaca acaacttcaa tggtggtcag ccacctcaag gcaatacaga aggtttattg
    32341 ggagaatacg gaatcaatat cacagaacaa gcacgacaag gtgatatcga tcctgtgatc
    32401 ggacgcgatg acgaaatcaa acgagtcatt gaaattttaa atcgccgaac caagaacaat
    32461 cctgtcttga ttggagaacc aggtgttggt aaaacagcag ttgttgaagg tttagcacaa
    32521 aaaatcgtag atggtgatgt accgcaaaaa ttaatggaca aagaagtcat tcgtttagat
    32581 gtcgtatctt tagtccaagg tactggtata cgaggacaat ttgaagaacg tatgcaaaaa
    32641 ttgattgaag agatccgtca agcagaaaat gtgatcctat tcatagatga agttcacgaa
    32701 atcgtcggtg ctggttctgc tggtgatgga aatatggatg ctggtaatat tttaaaacca
    32761 gctttagctc gaggagaatt gcaaatggtt ggtgctacta ccttaaatga gtaccgcatc
    32821 atcgaaaaag acgctgcttt agaacgtcgt atgcaacctg tacgggtaga tgaaccaact
    32881 gtcgaagaaa cgatcagtat tttgaaaggt ttgcaaaaac gttatgaaga ctatcatcat
    32941 gtaaaatata ctgatgaggc catcgaagca gccgcaactt tatccaatcg ttacgtccaa
    33001 gatcgcttct tgccggataa agccatcgat ttgctagatg aaacaggttc taagaaaaac
    33061 ttgacgatcc aaatcgttga tcctaaaaca atcgagaaaa aactgcaaga agcagaagaa
    33121 caaaaagttt tagcttctcg agaagaagat ttcgaaaaag cagcttatta tcgcgatcag
    33181 atcaataaac ttcaaaaaat gaaagaacgt cagctcactg aagaggaaac acctgtgatt
    33241 accgaaaaag atatggaaaa aatcgttgaa caacggacag gtattccagt gggtgaatta
    33301 aaagaaaaag aacagacaca actgaaaaac ttagcagatg acttgaaagc tcatgtcatc
    33361 ggacaagata acgctgtaga tcgagtagcg aaagcgattc gccgaaaccg tgttggatta
    33421 aacaaacaga atcgtccaat cggctccttc ttatttgttg gaccaactgg tgtaggtaaa
    33481 acagagcttg cgaaacaact tgcctacgaa ctattcggtt cacaagattc aatgattcgt
    33541 ttcgatatgt ctgaatatat ggaaaaacat agtgtctcta aattgattgg ttctcctcca
    33601 ggttatgtcg gatacgaaga agctggtcaa ttaacagaaa aagtacggag aaatccttac
    33661 agtcttgtct tgttagatga agtagaaaaa gctcatccag atgttttgca tatgttcttg
    33721 caaatcttag atgatggtcg attgacagat gcacaaggaa gaacggtcag ctttaaagat
    33781 acgatcatca ttatgacaag taatgccgga actggtaaag tagaagcaaa cgttggtttt
    33841 ggtgcggcac gcgaaggtgt tactcgttct gtattgaacc aattaaacaa ctactttaca
    33901 ccagaatttc tgaaccgttt tgacgggatc atcgaattca gtgcattatc aaaagaaaac
    33961 ttgatgacaa tcgtcacact aatgctagac gatgtcaacc aaatgctggc agcacagcaa
    34021 cttcacatcg aagttcctac gaatgtcaaa gaaaaattag ttgacttagg ctatgatcca
    34081 tctatgggtg ctcgtcctct tcgacgcacg atccaagaac aaatcgaaga tggtatcgct
    34141 gaattttatc ttgatcaccc ttctatccat gagttgaaag caaaactgga taaagatgga
    34201 aaaatcatcg ttacttctaa accagaacgt ttggctaaag aatcagccga agaaacggct
    34261 gaataaatcc agttttatag cgtgagacgg tatttctttg agaaatgccg tctcattctt
    34321 ttttcagaaa agtcaaaata ctgttcattt tataaaaaag aaattataat aagagaaaca
    34381 agcaattaaa aatacataaa agaggtgagc gccatgaaat tggtaaatgt aacaaacagc
    34441 cattcccgtc ttgtattaaa ccagcttgaa aacactgatg cccatctagt caaggtctac
    34501 acagccggaa ataccactat tgtctacact gaagcccctg aacataatga aattctgctg
    34561 atcaatgaca aacgtaaaat ccagccgaaa gaaatcgaag atgctaaaaa ttatttctta
    34621 gataaaatca aagacgccgt ttaccacgag gatgaaatca aagtaatcga attggcaggc
    34681 cttgttgaaa tctcgattcc aaaacatgaa ttaggcgcta cattagccgt gtaaacaaat
    34741 tttgaacata ataattaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc
    34801 taaacacgta taaacggcga aagcagaagc aactccttcg gaaataagct gaaattcacg
    34861 aaaattgctt ttcaaatttt tgtgaattcc agcttatttc ttggagttaa acgcttctgt
    34921 ctcagcctct ttttctttct agctttttga tttttctctt ttcttttgta cttttctctt
    34981 ttcattttca gttctacgcg tgtctttatt tttaactttt tcctctttat ggatgattga
    35041 tcgtactttt tgtgcaattt gctcgttttt gtcccagtct tttacatcta ataatcgaca
    35101 taatcgtaac atctcttctt ttttctgttt ttttctttca cgtctttgcc attctgtttc
    35161 catgtgtcac actctccttt ctttaatcat atgtacgcaa aataattttt atattttttt
    35221 gattagacat ttctatgatt ttaatatagt aaaaagagcc gtcacggaaa atccgtcacg
    35281 gctctaaaca aaatatgaga ggctgttttt gtttggctat tcttattact tgatgcaggg
    35341 cagcttgtgt caagacttct ttacatcaaa ctttttaatt ttacattggg atatttatcc
    35401 gcaaaccagc gttctgcaaa ttggttctcg aataagaaca acggttggtc gaaacggtca
    35461 cgagccaaga tattgcgact tgaactcatc ttctcatcca aatcttctgg atcgatccag
    35521 cgagcgattt tgtgtcccat tggagacatg attacttcgg cgttatactc atttaacata
    35581 cgatattgga atacttcgaa ttgtagctga ccaacagctc caatgatata ttcttccgtt
    35641 agatatgttt tataaagctg aatcgctcct tcttgaacta attgatagat tcctttgtgg
    35701 aaggattttt gtttcatgac attttttgca gtcactttca taaacagctc tggagtaaat
    35761 gaagggagtt cttcataagc aacttttagt tttccttcga acaatgtatc cccaatctga
    35821 taattgcctg tatcatatac accgatgata tcgcctgcta ctgctttttc gacgttttct
    35881 ctcgaatctg ccataaattg tgtgacattg cttaatttca gttttttatt tgtacgttcc
    35941 aaccagacat ccattcctcg ttcgaatgtt ccagaacaga ttcggacaaa agcgattcgg
    36001 tcacgatggg ctggattcat atttgcttgg atcttgaata cgaaacctga aaattcttcc
    36061 tcataaggac ttaccatctg atcatcttgt gttttgtgtc cataaggagc tggtgccaat
    36121 tcaacgaaag tctctaaaaa agtctgtaca ccgaagttag tcaatgcaga accaaaaaat
    36181 actggtgtct gatcgccacg agcaattttt tcttgattaa atgcatctcc agcctctttg
    36241 attagttcta cttcttctaa gacttgttca tataaggaat tttcagttag aggatgattt
    36301 tcgggaagca gtccatcttc atccaattct actaatcgtt catcctgata attttccgga
    36361 cgataaaact ctacacgatt atggtagata tcataaagac cttctagccc tttacccata
    36421 ccgattggcc aattcatcgg ataagattcg atatctaata gctcttctaa ttcttctaac
    36481 aattccaatg gttcacgacc atcacgatct agtttgttga taaaagtaaa tatcgggatg
    36541 ccacgttttt ttacaacttg gaataatttc tttgtctgtg cttcgatccc ttttgcacta
    36601 tcgattacca tgaccgcact atccacggcc atcaaagtac gataagtatc ttcagaaaaa
    36661 tcttcatgtc ctggtgtatc caagatattt actcgtttcc cttgataatc aaactgcata
    36721 acagaactag taacagaaat cccacgttgt ttctcgattt ccatccagtc tgatttggca
    36781 aaattacctg tttttttgcc ttttacggtc ccggcttgac ggatagcccc accaaacaat
    36841 agtaattgtt ctgtaatcgt tgttttccca gcatccggat gggaaatgat cgcaaaagtt
    36901 ctgcgattgt ccacttgttg ctttaatttt ggattattca taacctaact ccatttcttc
    36961 cattcaatta tttatatttt ctctaggcac agattgtccg atctcttaaa gaaagacaat
    37021 ttcatatagg gctgtgacaa aagccgtgta gcagtctctt tttccgagta aacggcgttc
    37081 tagagacagc ctatcagcaa taagcccacc caagccaaaa atacgaaaag ctgtttttgc
    37141 ttggctgctc ttattactta atgcaggata gctttttcac aacctttgtc aactactaca
    37201 actgaatcag tatagcatgg attcagcgaa tgaaaaagcc accaaaccat aagagtcaaa
    37261 tatttttttg tcagctgact aaaagaaaag acgtgttgct tgtttattca agcaacacgt
    37321 ctttcataac caagtttcca attatcttct tggctcgtca tcttcgaatt cttttctgaa
    37381 gtatcttcgt tcttcttcag gttccgcttc tgtttcttcc ggatcatgaa aaatgacacg
    37441 gattttaagg attcgagaac cttccatttc ttcagaaacc agcgtaatat tatcgacatc
    37501 aaacgataac ttttcgcctt catccggaat catgcctaat gctgtaatca aataaccagc
    37561 catcgtatct acatcactca tatgcagatc actgtcaaaa gcttcattga actcatcaat
    37621 cagcatacgt ccttggatga tatattcgtg ttcatcgatt ttttcataaa gattctcaac
    37681 ttcatctgat tcatcatcga tttctccgac gatttcttct aaaaggtctt ctagtgttgc
    37741 taacccaacg acgccgccat attcatctaa taaaatagcc atctgattct gcgtcttttt
    37801 catttcatat aacagatcat caataaagac cgtttcagga acgaataaag gctcctgcat
    37861 gattttcttg atatctaaat tatcaaagcc gaatttatgg gcagctttta gtaaattctt
    37921 tgtatgaagg attccgacta ctttatcttt gtcttcgtta taaacaggga ttcttgaata
    37981 gttttcggat aaaacttcat tcacattttc ttccacagtg tcgttgatat caatcataaa
    38041 tgcatccgtt cgtgggacca tgacttctcg ggcaactttc gtatcaagag aaaaaacccc
    38101 ttggagcatt tctaattctt cattattcaa tacgccttcg ttttcaagca tataacgcat
    38161 ttcatctctg gtcatttttg aatcttcatc atcaaaagtc atcggcgtga tacgcgccaa
    38221 taaacttgtg gaagcagaaa gcagccagac gaagggctta gctactacac caatcaagcg
    38281 tatcagccct gaagtgaact ttgcgacttc ttctgattta tttaaagcaa tacgtttagg
    38341 gtacaattct ccaaaaacaa tcgatacata ggtcaaaata gccagcacaa tgatatttgc
    38401 aatatttttt gccgctgtgc cgccacctaa taccggagct aaccgttccg ataaagtatt
    38461 agctagtgaa gcaccagaca aaatgttgac caaagtgatt cctacttgga ttgtcgatag
    38521 gaaattattt ggattctgca atatttttaa aagcttttga gatttcacat ctccttcatc
    38581 agctttttgc tcgattcgat tcttattgat cgaaacaaca gcaatttcgg aagctgctaa
    38641 aaaagcattg atcaatgtca aaacgatcaa taataaaatc tgcgctaaca gcgactgact
    38701 ctcagggtca gcattcataa tcgcattctc tccttataaa attaattttt agtttacgat
    38761 agaaaaaaac gtggcactat agccacgtta aaatggtatc acaaagcaat tttctttgca
    38821 ataaaaacaa gtgtactaaa actacctacg aggtcgtagc aattttcttc ttgttttcat
    38881 tttgcttgtc ttctttgacg attttgatta tataggaaat gatcgtcttg cagattgcgt
    38941 aaaaaggaac acctaagaag ataccaagca atccggcaat atttccagct actagaagaa
    39001 cgataatgat cgttaatgga tggattttca gtgatttccc aattacatta ggataaatga
    39061 tattcccatc caactgttgg acgattagca caaccacaca acaaagtaat gcttttaccg
    39121 gatcattgaa gactgttact agaaatgcag gtgctagtcc tagataaggt cctaaatatg
    39181 gaattaggtt tgtcaatccc gcaatgaccc caaataagaa agcataatcc acaccaatta
    39241 ccatatatcc taaaaatgtg aaggtaccaa cgaataaaca ttcgattgct tgtccgctaa
    39301 tgtaattagc caatgtttta ttcagttgcc ccaataactc cacaatttgg tttcttcttt
    39361 tttctgggaa aaactgttgg atgtttggca ctagtttttc tccgtctttc aacatataga
    39421 acaagatgaa tggtgctgta atgattacta cggttgccga agcgatcgtt ccaacgatcg
    39481 aacctaaact attggatact ccactaagga attgctgaat gattgtcccg taagaaatgt
    39541 ctaattgctc aaaatattta ttgatatcta cttccttgaa caaaggcaat tcggctacct
    39601 cttttaacca gctttctacc tgtttgatga aatcaggcat attagatgcc aatgaggaaa
    39661 tttgctgtac tagacttggg atgacactaa gtaaaatcca aataattgct gcaactaaaa
    39721 ggagcagcac aattgcgaca gcccatattc ttttgatttt tgctttcatc aacagcttga
    39781 caataggatt caataaatag taaagaaagc ctgcaatcag tacaggtgca aataacgtgg
    39841 aaaaaaatgt cccgatcggt tcgaaaataa agtttatttc tgatgaaatc atgatcaatg
    39901 cagctatgat caataattca agcgaccaaa acattagttt agactgtcta agtttttcaa
    39961 acaatagatt tcctcctttc tttcttacta gtatatatta tattcgttaa aaattctttt
    40021 attctttttt tatttttgaa aacttgccat actttttatt tgttttattt tccagtatac
    40081 tatacgaaag gaaggtggct agaccatgaa agttgtacaa acaaaagata caatgagcaa
    40141 tatttactta gatgctgtac ggatcaggca tcaagttttt gtagtcgaac agggtgtgcc
    40201 tttgtctcga gaaatagaca aagatgaagc ccattgtatc cacttcgtcc tgtactcaga
    40261 taaaaaagaa ccgcaaggaa ctgtacgtct tttgccttta gaaaacggaa aaatgaaatt
    40321 acagcggatg gcgattcttt ctgaatacag acaccaaggg ttaggaaaaa tattgattga
    40381 agaagcagaa aactttgcta agaatcaagg ctataatacg attttattag gggcacagtc
    40441 cacagctgaa actttttacg aaaaactagg atatacagct tacggcgatc cttttgaaga
    40501 tgctggcatg cctcatattt atatgaaaaa gactttataa aaatttattt cgaaaaaagc
    40561 aaaaaacagc aagcttttga gaaaaatctc tcactggctt actgttcttt tttgtgttta
    40621 cttacgcgac aattgcttgt aacggttata ccaaatatca atatagcctt ccgagaacgg
    40681 gccatctcca ttattgatcc agtcaaccag aatcttcaca ttttctttta ggatgaagtc
    40741 aatatcgttc gggtaattca tcattttgct gtgcatctca tattcatcga catccaatag
    40801 tcgtttctcg ccgtcaggaa ataccttgat atccaagtca tagtcgatat atttcaaggc
    40861 ctcatcgtcc agcaaaaaag gtgaagctag attacaataa taggaaaccc ccttttctct
    40921 gatcattgct attacattga accagtattt tttatgaaaa taaacaatcg ctggttcgcg
    40981 cgttacccat cggcgtccat cagattcagt gactaatgtg tgatcattca cgccgatcat
    41041 agagtgttcg cttgttttta ataccatggt atctcgccac gttcgatgca atttgccgtc
    41101 gtgcttgtaa ctttggatcg tcacaaactc tccttctttt ggaactccca tagcaaccct
    41161 tccttaagca gcattttgtg ctttgtgttt gggtgttcat tacaccgaca tcataattat
    41221 tatatcaata aaaatgagct ttgcctagaa aggattccta ttgtttcgat ttttctctaa
    41281 ctgatctacc agtttcattt ggaccttagg aaaaacgacc gaatcaaatg catcaggctt
    41341 caaccacttc gaagttttgt tctcggtaaa ttcttgttct gctccctcgg ttgcccgtcc
    41401 gtaaaaaagg agaacatgcc atttcagatg actaaaaata tgagtaactt ctcctaaatg
    41461 tcgtgtctgc caaacaaaga gttcctgctt ttcaaatggg agattttgct cttcttctgc
    41521 tactaggtca tcaaacagat cgatttctgg ctttgtttcc cattcttttt tcaatcgctc
    41581 atactcctct tgtgtcactt ccatcattgg aaatgtccac atattcgcca gcaatttttg
    41641 gctatctctt tcttcaaaat aatacgctcc agaatgattt tgaagagctg cactgatata
    41701 ataaacgtct tttggctttg ctttttttgt ttttacagga aaactcgttt ggattcctcg
    41761 tttgttagct aaacaaaagg cttggatcgg acaagtctca cactttggag aagttggtgt
    41821 acagatagct gaacctagat ccatcattgc ttggttgaat tcacctggat gcttttcatc
    41881 aatgattttc cgcatcgctt catcaaagat tttcctgcta gaagcttttg cgatgtctgc
    41941 ttcaatgcaa aacaatctgc tgactactcg catcacgttg ccgtcaactg caggttctgg
    42001 aagtccaaat gcgatacttg caatcgcgcc tgtcgtatat ggtcctattc ccttcaatga
    42061 gctaatttct tcaggcgttt gcggcatttc cccatcaaat tctgacatga tctgtttagc
    42121 agcagcttgg atgttccggg ctcttgagta ataaccaagg ccctcccatg cttttaaaag
    42181 cttttcttct ggagcatttg ctagctcttc aattgtagga aaccattcca tgaaacgata
    42241 aaaataatcg atcactgtgt ctactctggt ttgctgaagc atgatctcag agatccagat
    42301 acgataagga tcacgattat agcgccaagg caggtttctt ttttcttgtt cataccattg
    42361 aatgaactga tcttgaaatt cttttgtttc tttatctgtc catttttccc attctttatt
    42421 cactttcctc ttccttttcc gtaatgaatc gctggatcat atccaaatca aatccttttt
    42481 gatataagct ttgctttact tttagatttc tttttttagg ttcaaacctt aaatttcttc
    42541 gccatagttt atctccttgt ttgactaaat aatcatattc tatttcttga tctgcttctt
    42601 gcggaagatc agctatcgct tgttggatca cttcttgaga aaagcctttc gtcatcaatg
    42661 tttgttggat ttttctcaat aattcttttt ggctttttcc gtgatttttt ccaaacgctt
    42721 tttcggctgt ctgatgtgca ttttgaactt ggtcttcaaa tgtatattgg ctgagcgctt
    42781 gttcaatgat ttcaggtttc aaaccttttt gctgcatctg ctgcgctaat ttctttggtc
    42841 ctttgtcact taagcgcata ttcgtgcgca cataactttc cccatagacc aaatcatcga
    42901 caaggtccaa ttcttttaag cgggctacga ttttatttcg atcttcttga aggatttcct
    42961 tttcttttaa gtatgttcgg atttcttttt ccgatcgcaa ctgataactt aagtaattca
    43021 ttgctaggtg aaaaccgaaa tcagctccgc tactcttctt gatctcttgg atagtttctt
    43081 cgtctaattc ccgtcctttt aataatcgat agcgtactaa tacatcttca gatacttgta
    43141 aagcttctcc ttcagataaa tctacgcgat agaaagggcc tttgccttta ctgattctcg
    43201 taacggttaa cataaacatc ctcctcgaac atatattctc tatcatacca cagaaaatcc
    43261 ccgtaatcag gtattatatg ttagaataaa ccacagaaaa aagaaaaagg gagatactta
    43321 tggcagaaac aattgtcaaa actggacaaa cggttccttt gaaaatcaag cgtttaggca
    43381 taaatggtga aggaatcggt tatttcaaac ggttgatcat atttgttcca tatgcactac
    43441 caaaagaaga agtactagtg aaaatcacga aagcaactcc tcgctatgca gaaggagaat
    43501 taataaaagt caaaaaaaca agcaaagatc gcgtagtggc accatgtcct gtttactatg
    43561 aatgcggtgg ctgtcaatta caacacttag cttatcaagc tcaattggat tttaaaaagg
    43621 atctgctttt gcaagcattg gaaaaattca aaccagcagg ctttcgatct tatcaacttt
    43681 tgccgacgat cgggatggat gagccttggc attatagaaa caaagcacaa tttcagttac
    43741 gaaaaaataa gcagactcaa aaaattgaag ctggtttata cgaagcaaac tctcatcagt
    43801 tagtccctat aacagactgc ttggttcaag aacctcgaac acaaaaagta atgaatactg
    43861 ttgttcaact attgaataaa tttgatgcac ccatctatga tgaacggaca aacagtggaa
    43921 tcttccgcac aatcatggtt agaatcggtg ttaaaactgg ggagttacaa gttgttttta
    43981 ttactcgcag taaaaaattc ccgcaaaaaa acgcaatgat ccgtgagatc aatgaacgac
    44041 tgcccgaagt tgtttcaatc atgcaaaatg tccaggcaca aaaaacgtct ctcgtgatgg
    44101 gggatgaaac gatccactta tggggaaaag aagccattga agaacaaatc aatgaagtga
    44161 ctttcgatct ttctcctcgt gccttctttc aactcaatcc tcagcagacc gaattgcttt
    44221 atggcgaagg aatcaaagca ttagatgtcc agcctaatga aacgatcgtg gatgcttatt
    44281 gcggagttgg gacgatcggc ttaagtgtag caaaacaagc caaagaagta cggggaatgg
    44341 ataccgttcc tcaagcaatc gctgatgcaa aaaaaaatgc ggaaagatta ggatatcaca
    44401 acactcgata tgaagtcggg acagcagagc aagttctgcc taaatggttg aatgaaggtt
    44461 ttcagcctga tggtatcatc gtagatccac cacgtacggg tttggataac gcattgatcc
    44521 aatcattatt gaaataccct ccaaaaaaac ttgtttatat ctcctgtaat gtttctacac
    44581 ttgccagaga tctggttaat ttaagtaaaa agttcaagat tgaatattta cagtccgtcg
    44641 acatgtttcc tcagactgca cgttgtgaag ttgtcgtgaa gatgacgaga ctcgctgact
    44701 aaatgaaaga ggttgtgaaa aagtctgccc tgtatcaagt aataagaaca gccaaacaaa
    44761 aatagctctt catgttttat gaatactgta cttgtgaccg aagagttaac aggaggacac
    44821 tatttattta aaaaaagggt tgtgacatag tttttgtcac agcccttttt gattattatt
    44881 ggatattcac gtctatcact tgataaaatg catttgtcgt atcgctgata ttccatactg
    44941 ctaaaatcac attatatcct tttcgatcct gcggaagtgt gatcgtttgg ttgactgttt
    45001 ttggtggaac agttgctttg tcgtctattt ttgtgatcaa ttcaaaatca ctaaatttca
    45061 aaggttgatt aggattccaa gttggtttgg taatgtagta atcccaagta cttgtccgat
    45121 gttgtgctgt taaattccaa gtaatattta atgttcctgg attaaccatg tttttatgcc
    45181 atctgttaga tgtctgttca tctaaaggct caaagccgct gactcctgca ctagcaattt
    45241 ttccatcaat gaatgtattt ttggtagctt cgatactttg cggttcccat tgtgctcttc
    45301 cgacattttg atttaagttt cctgctgctg atgttcctag gtatgcacgg cttcctggag
    45361 aagtaatata accatgcgca aaacctggaa tgctaaaacc gaacaaccct aaactaacta
    45421 acccaataaa caataacgta ctaatctttt tcatgtagaa acctccttca tttgataacc
    45481 acattgtaaa cgctttattg tattaacaca aacattatgc ttttataatt ttatgttgaa
    45541 gtaaaa
//
LOCUS       DACBYO010000014        42961 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.014, whole genome shotgun sequence.
ACCESSION   DACBYO010000014 DACBYO010000000
VERSION     DACBYO010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.014"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            591..1280
                     /locus_tag="IVD26_000746"
     CDS             591..1280
                     /locus_tag="IVD26_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6078746.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="IVD26_000747"
     CDS             1267..2475
                     /locus_tag="IVD26_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6078747.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="IVD26_000748"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="IVD26_000748"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAP6078748.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="IVD26_000749"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="IVD26_000749"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAP6078749.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="IVD26_000750"
     CDS             complement(6578..7273)
                     /locus_tag="IVD26_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAP6078750.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="IVD26_000751"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="IVD26_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAP6078751.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="IVD26_000752"
     CDS             complement(8472..8663)
                     /locus_tag="IVD26_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAP6078752.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="IVD26_000753"
     CDS             complement(8684..9574)
                     /locus_tag="IVD26_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAP6078753.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="IVD26_000754"
     CDS             complement(9561..10328)
                     /locus_tag="IVD26_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP6078754.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="IVD26_000755"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="IVD26_000755"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAP6078755.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="IVD26_000756"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="IVD26_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAP6078756.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="IVD26_000757"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="IVD26_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAP6078757.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14944..15282
                     /locus_tag="IVD26_000758"
     CDS             14944..15282
                     /locus_tag="IVD26_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078758.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="IVD26_000759"
     CDS             complement(15450..16208)
                     /locus_tag="IVD26_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAP6078759.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="IVD26_000760"
     CDS             complement(16226..17044)
                     /locus_tag="IVD26_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP6078760.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="IVD26_000761"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="IVD26_000761"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAP6078761.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="IVD26_000762"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="IVD26_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAP6078762.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18173..19507
                     /gene="dnaA"
                     /locus_tag="IVD26_000763"
     CDS             18173..19507
                     /gene="dnaA"
                     /locus_tag="IVD26_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAP6078763.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19705..20835
                     /gene="dnaN"
                     /locus_tag="IVD26_000764"
     CDS             19705..20835
                     /gene="dnaN"
                     /locus_tag="IVD26_000764"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAP6078764.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21064..21306
                     /gene="yaaA"
                     /locus_tag="IVD26_000765"
     CDS             21064..21306
                     /gene="yaaA"
                     /locus_tag="IVD26_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAP6078765.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21293..22417
                     /gene="recF"
                     /locus_tag="IVD26_000766"
     CDS             21293..22417
                     /gene="recF"
                     /locus_tag="IVD26_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAP6078766.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22414..24360
                     /gene="gyrB"
                     /locus_tag="IVD26_000767"
     CDS             22414..24360
                     /gene="gyrB"
                     /locus_tag="IVD26_000767"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAP6078767.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24380..26851
                     /gene="gyrA"
                     /locus_tag="IVD26_000768"
     CDS             24380..26851
                     /gene="gyrA"
                     /locus_tag="IVD26_000768"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAP6078768.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27087..27386
                     /locus_tag="IVD26_000769"
     CDS             27087..27386
                     /locus_tag="IVD26_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAP6078769.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27436..27948
                     /gene="ssb"
                     /locus_tag="IVD26_000770"
     CDS             27436..27948
                     /gene="ssb"
                     /locus_tag="IVD26_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP6078770.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27974..28210
                     /gene="rpsR"
                     /locus_tag="IVD26_000771"
     CDS             27974..28210
                     /gene="rpsR"
                     /locus_tag="IVD26_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAP6078771.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28353..30326
                     /locus_tag="IVD26_000772"
     CDS             28353..30326
                     /locus_tag="IVD26_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAP6078772.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30332..30784
                     /gene="rplI"
                     /locus_tag="IVD26_000773"
     CDS             30332..30784
                     /gene="rplI"
                     /locus_tag="IVD26_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAP6078773.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31058..32425
                     /gene="dnaB"
                     /locus_tag="IVD26_000774"
     CDS             31058..32425
                     /gene="dnaB"
                     /locus_tag="IVD26_000774"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAP6078774.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33205..34497
                     /locus_tag="IVD26_000775"
     CDS             33205..34497
                     /locus_tag="IVD26_000775"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAP6078775.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35284..36147
                     /locus_tag="IVD26_000776"
     CDS             35284..36147
                     /locus_tag="IVD26_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP6078776.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36276..37898)
                     /locus_tag="IVD26_000777"
     CDS             complement(36276..37898)
                     /locus_tag="IVD26_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6078777.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38147..38668
                     /locus_tag="IVD26_000778"
     CDS             38147..38668
                     /locus_tag="IVD26_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078778.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38854..40584)
                     /gene="spxB"
                     /locus_tag="IVD26_000779"
     CDS             complement(38854..40584)
                     /gene="spxB"
                     /locus_tag="IVD26_000779"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAP6078779.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40749..41567
                     /locus_tag="IVD26_000780"
     CDS             40749..41567
                     /locus_tag="IVD26_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAP6078780.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41670..41867)
                     /locus_tag="IVD26_000781"
     CDS             complement(41670..41867)
                     /locus_tag="IVD26_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078781.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            42036..42614
                     /locus_tag="IVD26_000782"
     CDS             42036..42614
                     /locus_tag="IVD26_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAP6078782.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
BASE COUNT        13035 a         8236 c         8491 g        13199 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgcggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gagtcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa tggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggtgatttc ctgtgtattc cgtctcctaa ctattggtat atctatattt
    17941 tttatccaca gatgcaagag gaaatctatt gatttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    18061 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    18121 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    18181 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18241 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18301 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18361 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18421 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18481 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18541 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18601 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18661 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18721 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18781 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18841 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18901 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgcctcgttt ctcgctttgc
    18961 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    19021 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    19081 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    19141 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    19201 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19261 ttatcacatc caattgaaag atatcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19321 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19381 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19441 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19501 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19561 aaaagttatg cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19621 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19681 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19741 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19801 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19861 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19921 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19981 tttactttag aagttttaga aaataaacaa gtagcgatta cttctggaaa agcgaatttt
    20041 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    20101 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    20161 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    20221 ttattggctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20281 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20341 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20401 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatcctga taccaatcgt
    20461 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20521 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20581 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20641 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20701 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20761 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20821 gtacgtacaa attaacaatg attttcattg ttcttgaaaa tttaattgaa aagaaataga
    20881 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20941 gtttaaatca ccttttttag attaaatcgt cttatatgga aaaatatatg gataaatttg
    21001 ttttattgcg aaaaaaaagg tataatagag tatactttta ataatgaaaa tgagggatgg
    21061 gcattgaaac aacaagtcat tctaaatacg gaattcatga cgttgggcca aatgttgaaa
    21121 gaagtcacag ttatcggtag tggcggacaa gcaaaatggt atttggcaga aaacactgtg
    21181 ttagtcgatg gcgaaccaga aaatcgtcgt ggacgcaaac tttatcccgg catgatggtt
    21241 gaagttccag aagtaggaac tttttttatg gtaaaaaaag gaaacgacga taatgaggct
    21301 gaataagctg tatttaaaaa attatcgaaa ttacgaagag ctgaacatcg aattttccaa
    21361 gaacctcgtc atctttttag gagaaaatgc gcaaggaaaa acgaatcttt tggaaagtat
    21421 ctacgtatta gctatgacgc gaagtcatcg gacaagtagt gagcaggaat tgattggctg
    21481 gactgacgat caggcgatga ttcaaggaga gatcacaaaa ggttcatcca ctcttccatt
    21541 agaaatctta ttatctaaaa aaggccgaaa aaccaagatc aaccatatcg aacaaaaaaa
    21601 gttaagtact tacgtgggac aaatgaatgt cattttattt gcaccagaag atctttcttt
    21661 agtaaaaggc agcccgcaga tcaggcggaa gtttttagat atggaattag gccagatcaa
    21721 tccaatctat ctttatgatc ttgtccaata ccaagcaatt ttgaaacaaa gaaaccagta
    21781 tttaaagcaa ttgaatgaaa aaaaacaaac tgatttgctt tatttggata ttttgtccga
    21841 acaactagca gcgtttggca gcaaagtatt gaaagcaaga gcacagttcg tcaagcgatt
    21901 ggagttttgg gctaattctt tgcatcagca aatcacccat caaaaagagc agctggaaat
    21961 cgagtatctc accgcagtcg attctttaga aacacatacg caagagcaaa tccaagaaca
    22021 atttctcgca cttttgaacc aaaataaaaa gaaagacctt tttcggggaa caacgacagt
    22081 tggtcctcat cgtgacgatc tttccttttt tattaatcag aaaaatgtgc agacttatgg
    22141 atcgcaagga cagcaaagaa caactgcact aagtgtcaaa ttagcagaaa tcgatttgat
    22201 taaagaagag acgggggaat atccaatcct tttgttagat gatgtgatga gcgagctgga
    22261 tgatagtcgt caactccatc tgctagaaac aatcgaagga aaagttcaaa cgttcttaac
    22321 aacaacgaca cttgaccatg taaaaaataa aatgactgtt gaacctgaga ttttttatgt
    22381 tcaacaaggg aaactaaaag gagaagaaac tgaatgacag aagaaagaag tttagtagaa
    22441 cgcgctaaag agtatgatgc cagtcagatt caagtacttg aaggacttga agccgttcgt
    22501 aaacgacctg gcatgtatat cggttcgact agttctgagg gtctgcatca ccttgtttgg
    22561 gaaattgtcg ataattcgat cgatgaagta ttagcaggtt ttgcaacgaa aatccatgtg
    22621 attattgaaa aagacaacag tatcaccgtt attgacgacg gtcgggggat acctgtagat
    22681 atccaggcaa aaactggacg tcctgcagtt gaaacggtct ttactgtttt acatgctgga
    22741 ggaaaattcg gcggtggtgg gtacaaagtt tctggtggac ttcacggagt aggatcttct
    22801 gttgttaacg cgctttctac acagcttgat gtcaaagtat acaaagaagg aaatgtgtac
    22861 tatcaagaat atcgtcgtgg agctgtagtg gacgacttaa agattatcga acaaacggat
    22921 cgccatggaa caacggttca ctttacgcca gaccctgaaa tttttacaga gacaactgag
    22981 tttgattttt caaaattggc tacccggatc cgtgaacttg ctttcttgaa ccgcgggatg
    23041 cgtatatcga ttgaagacaa acgagaagaa gaaccagtca tcaatgaata ccattatgac
    23101 ggcgggatta aaagttatgt cgaatacttg aatgcaaaca aaaccgtgat ttttccagaa
    23161 cctgtatatt tggaaggtga acagcaagat atcgcagttg aagtctctat gcaatataca
    23221 gacggctacc attccaatat catgagtttt gccaacaata tccatacgta tgaaggcgga
    23281 acacatgaat caggattcaa gactgcttta actcgtgtga taaatgatta tgcccgaaaa
    23341 caaaagctga tgaaagaaaa tgacgacaac ttgaccggtg aagacgtgcg agaaggattg
    23401 acagctgtta tttctatcaa gcatcctgac cctcaattcg aaggacaaac aaaaacaaaa
    23461 ttgggcaatt ccgaagtacg gacagtcact gatcggttat ttagcgaaca tttcatgaaa
    23521 ttcttgctgg aaaacccaag tgtgggccgt caaattgttg aaaaaggatt actagcttcc
    23581 agagctcgtc tagcagcgaa acgtgcgcgt gaagtaacga gacgtaaagg tgctttagag
    23641 attagtaatc tgccaggaaa attagcggac tgctctagca acgatcctga aaaatgcgaa
    23701 ttgttcatcg tcgaaggaga ttcggccggc ggatcagcta agcaaggtcg taatcgagag
    23761 tttcaagcca tcttgcctat tcgtgggaaa atcttgaatg ttgaaaaagc aagcatggac
    23821 aagatcttgg caaatgaaga gatccggtct ttatttactg ctatgggtac agggtttgga
    23881 gaagattttg atgtatcgaa agctcgctac cacaaattag ttatcatgac tgatgccgat
    23941 gtcgacggcg cgcatatccg tacattgctg ctgactcttt tttatcgtta catgcgtcct
    24001 attgttgaag ctggatacgt ctatattgct cagccacctt tatacggggt aaaacaaggg
    24061 aagaatatta cgtatgtaca accaggaaaa aatgcagaag aagagttgaa acaagtcgtt
    24121 gcttcacttc ctgcctcacc aaaaccaagc gttcagcgtt ataaaggact tggagaaatg
    24181 gatgatcatc aactatggga aacaactatg gacccaagca atcggatgat ggcccgcgtc
    24241 agtgtggacg atgctattgc agcagatcag atatttgaaa tgttgatggg ggatcgagta
    24301 gaaccccgtc gtgcattcat cgaggaaaat gcacactatg tgaagaactt agatatttaa
    24361 tcatgaagga ggaaaaagaa tgagtgaaga aatcagagaa aacatccatg atgtcaatct
    24421 aaccagcgaa atgaaagact ccttcatcga ttatgcgatg agtgttattg tcgcacgtgc
    24481 acttcctgat gtcagagatg gtctgaaacc cgttcatcgc cgtattttat acggcatgaa
    24541 cgaattaggt gtaacaccgg ataaagccca taaaaaatct gccagaatcg tcggagatgt
    24601 catgggtaaa taccatcctc atggagacta tgcgatctat gagtcaatgg tacggatggc
    24661 acagccattc agctaccgtt atatgctagt ggatggtcat ggaaactttg gttctgttga
    24721 cggtgacggt gccgccgcta tgcgttatac cgaagcacgg atgagcaaaa tcgctacaga
    24781 aatgctgcgt gatatcaata agaacactgt tgatttccaa agcaactatg atgatacaga
    24841 aaaagaacca gttgtactac ctgctcgctt cccgaatctt ttagtgaacg gaacaacggg
    24901 gatcgccgta ggtatggcca cgaatatccc acctcataac ttgtctgagg tagtagcggc
    24961 tatcgatttg ctgatggata atcctgatgt gacgaccaat gaattgatgg aagtattacc
    25021 tggaccagat tttccaacag gtggtttggt tatgggaaaa tcaggaatcc gaagagcgta
    25081 tgaaacaggt aagggttcta ttaccgtacg tgcaaaagtt gagattactg agatgccaaa
    25141 tggtaaagaa cggatcatcg tgacagaatt gccttatatg gtcaataaag caaaattgat
    25201 cgaacggatt tctgaactgc acagagacaa gcgtatcgaa gggatcacag atttgcggga
    25261 cgaatcttcc cgtgaaggta tgcggatcgt cattgacatc cgtcgtgacg ccagcgcatc
    25321 tgttatcttg aataacttat ataaattgac atccttgcaa aattcatttg gattcaatat
    25381 gttggcgatc gaaaaaggtg tgccgaaagt tttgagcttg aaacaaattc ttgaaaacta
    25441 tatcgaacat cagcgcgaag tcatcacaag acggacagtc tttgaaaaag aaaaagcaga
    25501 agcaagggca cacattttag aaggtttgcg tattgctttg gatcatatcg atgaaatcat
    25561 tgcgattatc cgcgggtcta aatcagatga cgaagcaaaa gcgacgatga tcgaacggtt
    25621 cgatttatcc gatcgccagt ctcaagctat tttagatatg cgtttacgcc gattgaccgg
    25681 tttggaacgg gaaaaaatcg aaaatgaata ccaagaactc ttaaaactga ttgaagattt
    25741 aactgacatt ctggcaagac cagaacgtgt tacagaaatc atcaagaatg aattagcaga
    25801 cttgaatcaa cgatttggtg ataaacgacg cacagaatta ctagtcggtg aggtcttaag
    25861 tctggaagat gaagatttaa tcgaagaaga agaaatcgtt attacattga caaacaatgg
    25921 ttacatcaaa cgtttggcaa ataatgaatt cagagctcaa cgaaggggtg gacgtggtgt
    25981 ccaaggaatg ggtatccaca atgacgactt cgtcaaaaat ctggtttctt gttctaccca
    26041 tgatacattg ttattcttta cgaataacgg aaaagtgtat cgggcaaaag gatacgaaat
    26101 tccagaatac gggcgcacag ccaaaggaat accaattatc aatttactag gtatcgattc
    26161 gagtgaaagc atccaggcaa tcattgcggt gacgggagaa gcagaagaag gccactatct
    26221 cttctttacg acgcgtcaag gtacagtaaa acgtacttct gtcactgctt ttgctaacat
    26281 ccgaagtaat ggtctgatcg caattggttt gaaagaagac gatgagctcg tcaatgtgct
    26341 actgacagat ggtcaatcta atatcattat tggaacacat aacggctact ctgtcacttt
    26401 caaagaagaa gcagtccgcg atatgggacg tacagcttcc ggggttagag gaatacgcct
    26461 gcgtgaggaa gattatgtcg ttggggcagc cttaatgaag gaagatcaag aagtattagt
    26521 gatcacagaa aaaggttacg gaaaacggac aaaagtatcg gaatatccag tgaaaggccg
    26581 cggaggtaaa gggatcaaaa cggcgaacat cactgaaaaa aatggtccac tagctggatt
    26641 gaccactgtt tctggagatg aagacatcat gctgattaca gataaaggtg tcattatccg
    26701 tttcaacgta tcgactgttt ctcaaactgg acgttcaaca ttaggcgtac gtttgatgaa
    26761 gatggaagct gatacgaaag ttgtcacgat ggcagcagtc gaaccagaag ctgcagaaca
    26821 aacagttgaa gaacaaggat cagaagaata gccatcaaga ctaattgtgt aagctagcaa
    26881 gaatgaccga ttaaaaaatc tggttattcc tgctggcttt tttgattagt tgaatttctc
    26941 ttaaaatatt cgaaactgtt cattctgtat tgcttttgac caaaatagag tgtataataa
    27001 gagcttgtga gtagtctaat taattagata actctccttg ctcttaggaa cctaagagcc
    27061 gaaagtccac agggaggtga atatcaatgg aaaacacgaa atatgaaatc atgtacatta
    27121 ttcgtccaaa cattgatgaa gaagcaaaaa ctgctttaat cgaacgtttc gatgcaatct
    27181 tgaaagataa cggagcagaa gttatcgaat caaaagattg ggaaaaacgc cgtttcgctt
    27241 atgaaatgaa cggttaccgt gaaggtatct atcacatcgt taaagtatct tctccatcat
    27301 cagcaaatgc tgtcaatgaa tttgaccgtc ttgctaaaat caacgacgat atcattcgtc
    27361 acatgattgt taaagaagaa gcttaattgt tgtttcatgt gaaacaatag aaaacgatga
    27421 gaggagatga ctattttgat taataatgtt gtattagttg gacgtctgac gaaagatcca
    27481 gatttgcgtt acacagcaag tggtacggca gtcgcaacat ttactttggc tgtgaatcgt
    27541 aattttacaa accaaagcgg caatcgcgag gctgatttta tcaactgtgt gatttggcgc
    27601 aaatcagcag aaactttagc aaactatgct cgtaaaggaa cacttttagg tgttactgga
    27661 cgtatccaaa ctcgttctta tgataatcag caaggacaac gtgtatacgt gacagaagta
    27721 gtagctgaca acttccaatt gctggaaagt cgttctgcat ctgaaaatcg ccaacaaagc
    27781 ggcggattcc aaagttctgg tcaatcagct ggcggatttg gcggaaacaa taactctaat
    27841 caaacatctc aatcatccaa cggtatgcct gatttcgacc gtgatacttc tgacccattc
    27901 ggctcaagtt caacgatcga catttcagac gatgatttac cattctaaac gaatttgata
    27961 ggagggaaat agaatggcac aacaaagaag aggcggacgt aaacgtcgta aagtagacta
    28021 cattgctgct aaccatattg aatatatcga ttataaagat atcgaattac taaaaagatt
    28081 tatttcagaa cgcggtaaaa tcttgccacg tcgtgtaact ggtacaggcg ctaaaaacca
    28141 acgtaaaatt actgttgcaa tcaaacgcgc tcgtatcatg ggcttgctac ctttcgttag
    28201 cgaagactaa taaatcctag gaattgaatg actgatcctt ttgatcagct attcaattcc
    28261 tttttttctg taaaaataac ctctattcgt ttagtcgctc gaatgacgaa agttatggta
    28321 aaatcaaatt agtcatatat gggaggaaaa ttatggaaaa taaaaacaat catttatccc
    28381 cgaaacctct cttccttatc ctgtttatat taatcgaagt attggtagtc ttaattttac
    28441 catttcgttt tgttagcgct tcggtcattc tattgatgaa tttatggggt gttcgctatt
    28501 ggttgaaaat gaaacgttgg cttattttaa ataaacgtga aaaaatccag caggcttcga
    28561 ctgtagctga aaccaatcta gcttatgtct cagaagtcat gcctgtagga gtgattgctt
    28621 atcagccatc aagccaaaaa atcgaatggc tcaatccatt agcattgaaa atcaaagatc
    28681 aaagtggatt aacagaggaa gaattgctag atactttttt tactgcaaaa gaaaaaaaga
    28741 aaaaccaagt ctatctagca gataaaacat ttcagtttga tatggataca gtaaagggtg
    28801 ttgtttattt taatgatatt acccaaaacc agttgttaaa actccatcag acgaacagtc
    28861 agccggtgat tggtatttta tctattgata actatgcaga tgccattgat aaattggatg
    28921 acaaagagat ttcttatttg aactctttcg tcactacact agtttctgac tggatgaatg
    28981 aataccatgt ctttttcaaa agaatcaacg cagaacggtt tttcttcgta gcacagatga
    29041 tcgatctgaa aaagatgatg gataaaaaat ttgatttgct ggatcgcttt cgagcagaag
    29101 ctgaaaaaca gagctcgcct atcaccctta gtatggggat tgcttatggc tcaagaaccc
    29161 tcgatgaaat cggtggagaa gctcagaata atttagatgt tgctttagtc cgtggaggcg
    29221 accaagttgt cgtgaaagag gtaaaagaag gagcaaaacc tgtttattat ggggggaaat
    29281 ctgctaagaa tgtcaaacgc acgcgtgttc gttctcgagc gatgagtacc gctttgcgtc
    29341 ggatttttga tgaaacaggc gatgtgttta tcatggggca caagtttccg gatatggatg
    29401 ctttaggctc tgcttttggt gtcagttgtc tggcacgctt caaccagaaa aaagcttaca
    29461 tcgttatcaa cgagaacgag atcattccag atgtagaacg gtgtcttgaa gaaatccata
    29521 agcatcctga attagaaatg caactaatct ctccagaacg tgccatagag ctgaaaaaag
    29581 aagaggacct cctcgtgatg gtggattacc ataaaccttc tctatcgatc tctcagggcc
    29641 tatatgagca atttgataag attgtgatca ttgatcacca tcgtcgtggg gaagagtttc
    29701 caagtaaacc tctgctgact tatatcgaat cttcagcttc ttcagcttca gagctagttt
    29761 ctgagctgat ccaataccaa agcagcaaaa caaatcgctt agatcgtttt gaggccacat
    29821 tattgcttgc agggatggtt gtagatacaa atagtttcaa tgtccgtaca actgcacgaa
    29881 cttttgacgt tgccagctat ttaaggtctt gtggagcaga cgcatcctta gtacaatatt
    29941 tattgagctc ggatttagcg acatacttgg agatcagcaa tttgattgct ggaagcgact
    30001 atgtgacttc tgatattgtt gtggcggcag ggacagacga aaaagagtat aatagtgtta
    30061 tagcagcaaa aacagcagat acattgcttt cgatgatcaa tatcaatgca gctttcgtca
    30121 ttacaaagcg gacagacggc ttgattggga tcagtgccag aagtaccggc acgatcaacg
    30181 tccaaatcat catggaatcc ttaggtggcg gaggacactt cacaaacgca gctactcaac
    30241 tggaaaatac gacagttgag gaaacaaaac agaagctatt tgctgcaatc aaagaaaata
    30301 tgaatcaaat atatgataag gagtaatcca aatgaaagta atttttttac aagatgtaaa
    30361 aggaaaaggt aaaaaagggg acatcaaaga agttccagca ggttatgcac aaaattatct
    30421 aatcaaaaat aacttggcaa aagaagcaac gaaaagcagt atcagtcagt tagcaggaca
    30481 aaagaaagca caagaaaaac acgaagctga aatcttggaa gaagctaaaa agttaaaaga
    30541 attcttggaa aaagaagata ctgtagtcga attgaaggcg aaagcagggg aagacagccg
    30601 tttgtttggt tcgatccctt caaaacaaat tgctgaaggg ttaaacaaac aatacaaaat
    30661 caaattagat aaacgaaaaa tcgaattaga aaatccgatc cgttcactag gctacacaaa
    30721 cgtacctgtt aagcttcatc atgaggtgac ggctacgatc aaagttcatg tcgtacaaga
    30781 ataacaaatc ttgatagcga tgttcagctg gtaagtataa ccagaaggaa aaaagacaaa
    30841 ccgaaattta tctgagaaaa cagctgcagc aatgaaagca aaagctgcaa atcgatttca
    30901 gattgatttc ggtttctttt ttgggaacag caaaatagca taaagaaaac gagtataata
    30961 aaagagaact atttttttat tacactttcg gtacgaatga tgacttttct ctcattttct
    31021 tgtaaaatga agcaattgaa gacaaggagc gatacgtatg aatgaagtgt ggcaggatcg
    31081 aatcccaccg caaaatattg aagctgaaca agcggtttta ggctctgttt ttcttgacgc
    31141 agaaacgatc attgatgcca tggagtacat agagccaaaa gacttttatc gtcgtggcca
    31201 tcaaattatt tttgagacaa tgatcgagtt aaatgatcgt aatgaagcga ttgacgtggt
    31261 tactgtcaaa gaccggctgg aacaagccaa tttgttagaa gatgccggtg gtttaagtta
    31321 tctctcagac ttggcattag cagttccgac agcagcaaat atcgtctact atgcgaaaat
    31381 cgttgaagaa aaatcattgc tgcgtacatt gatccagaca gcaacaggaa tcgttacgaa
    31441 aggattcgag caaggagaag aagttcaaac aattttagat gatgccgaac gcagtatctt
    31501 ggaggtttcg gaaaaaagaa atcgaagcgg ctttttatct attgctgaag tactgaactc
    31561 cacgattgaa aatatcgatc gactagctca aaacaatgaa gaaatcacag gtctaccaac
    31621 tggctatcaa ggtctggata aaatgacagc aggtttccag cccgaagaac taatcattct
    31681 tgctgcacgt ccagcggtag gtaaaacagc gtttgcattg aatattgctc aaaatgtagg
    31741 aacaaaaaca gatcgttctg ttgcgatatt tagtttggaa atgggggcag aatctcttgt
    31801 aaatcggatg ctttgtgcag aaggttcgat tgaggccagc catttacgta caggtcagct
    31861 ttcggaagaa gaatggtcga atctgatcgt tgcgatgggg agtctttctc gagcaaatat
    31921 ttttatcgat gatacaccag ggatcaaaat ctctgaaatc cgtgcgaaat gtcggaaact
    31981 agcgcaagaa aaaggcaatc taggcttgat attgatcgat tatttgcagt tgattgaagg
    32041 taacggtaaa gagaaccgtc aacaagaagt atcagatatc tctcgccaac tgaaaaaact
    32101 ggcgaaagag ctgaaagtac ctgtcattgc tctttcacag ttatctcgtg gagtagaaca
    32161 gcgacaagac aaacgaccag tgctaagtga tattcgtgaa tccggatcaa ttgaacaaga
    32221 tgcggacatc gtagccttct tgtatcgaga tgattattat gaaagagaag gcggagatga
    32281 cgatgatgga aacgagccaa aaaatgacaa cgtcatcgaa gtcatcatcg agaagaaccg
    32341 aagcggtgca cgaggaacag ttgaactact gtttatcaaa gaatacaata agttttcgtc
    32401 gctttcgcca agagaagaat tttaaagaag aggttgtgag ccttgagcaa tcccgagagc
    32461 tctcgtaaga agatgcaagg agtaaccgca ggaacgacta gagtacttaa tttaaacaga
    32521 tctccaaagg gattgtgaca aaagtcttgt cacagtccct ttttccgaat aaacggtgtt
    32581 caatcagctg acccttggta ttagctcagc aaacgtcaaa atatgaggaa ctattttgac
    32641 gtttgtttct ctaatactca ggtcaaaacg ctgatcttac gacctctttt ccttaaacgg
    32701 tgttctcctg ccaactcctc ggtcacaagt cacaatatca tcaaacatga gaagcagttt
    32761 tttgaaattg ctccttgtga ctcagagtta aacggcaggc tcacaacctc tttcttaaac
    32821 ggtgttcaaa agcttgcatc tgcggtaata cgcccaatca aacgaaaaat atgagaagct
    32881 atttttgttt ggctgttctt attacttgat gcaggacagc tttttcacaa cctctgattc
    32941 acggtgttcc aaaagtagct tcttcgaaaa ataagtcgaa atttcacaaa aatttgagaa
    33001 gcaattttcg tacattcctt cttatttctt gaagctgacc acttctgtta caacctcttt
    33061 tttaataacc attctaaaaa gataaagttc gttttttaag cgtttttata aaataaaaat
    33121 aaaaatcatt cgattttatt tgaaatatgt atctattatt gatacaatgg ttcaggatta
    33181 aataatatag aacgaggtgt tcacatgtca tctgtagtag tagtaggtac gcaatggggc
    33241 gatgaaggga aaggaaaaat cacagacttt ctcagtgaaa atgctgaagt gattgcacgg
    33301 taccaaggtg gcgacaatgc agggcacaca attaagttta acggtgtgac ttataaactg
    33361 catttgattc cttctgggat tttttataaa gacaagatca gtgtgatcgg aaacggcgtt
    33421 gtagtcaatc ctaaatcatt ggttaaagaa ttagcttatt tacatgaaaa aggtgtagaa
    33481 acaagtaatt tgcgtatttc tgaccgcgcg cacgtaatct tgccttatca tatcaaattg
    33541 gaccaattac aagaagatgc taagggcgaa aataagattg gtacaacgat taaaggaatc
    33601 ggacctgcct atatggataa agcagctcgt gtaggtatcc gtattgcaga cttattagat
    33661 aaagaaattt ttgaagaacg tcttcgtttg aatctagatg acaaaaaccg tcaatttgta
    33721 aaaatgtttg attcagaacc acttgatttt gacgatattt ttgaagaata ttatgaatac
    33781 ggacaacaaa tcaaacaata cgtcacagat acttccgtta tcttgaatga tgctttggat
    33841 gcaggcaaac gcgtgttgtt tgaaggcgca caaggtgtaa tgctggatat cgaccaggga
    33901 acttatcctt ttgttacttc ttctaaccca gtagccggtg gggtaacaat cggaagcggt
    33961 gtagggcctt caaaaatcaa taaagttgtc ggcgtctgca aagcctatac gtcacgtgtc
    34021 ggtgatggac catttccaac tgaattattt gatgaaacag gagaacaaat ccgcgaagta
    34081 ggacgagaat acggtacgac aactggtcgt ccgcgtcgtg taggctggtt tgattctgta
    34141 gttatgcgcc attctaaacg agtttcaggt attaccaacc tatctttaaa ctcgatcgat
    34201 gtattaagtg gattggaaac agtaaaaatt tgtacggctt atgaattaga tggcgaacta
    34261 atctaccact atccagcaag cttgaaagag ttgaaccgct gcaaaccaat ctatgaagaa
    34321 ttgccaggct ggtcagaaga cattacagga tgcaaaacac ttgcagaact gccagaaaac
    34381 gcacgtaact atgtacgtcg tatctcagag cttgttggtg tacgtatctc aacattttct
    34441 gtcggacctg atagaacaca aacaaacatc ttagaaagcg tctgggcgca aatctaagga
    34501 taaaaacgac gactgaatca ggacgttctt accagagcga gtcgaagtgt ttatctatac
    34561 gataataata acttgaagag gtagtgaaag agacgtttag ccttattgcc gataggctgt
    34621 ctcttgaaca ctgtttattc agaataaggg actgtgacaa aaaccgtgtc acagtccctt
    34681 tttccgaaca aacggtgttc aaaagcttgc atctacggca ctaagcccaa tcagatgaaa
    34741 aatatggagt gctattttta tctgattgtt cttactgctt gatgcagagc agctttttca
    34801 caacctctcc actaaacggt gttctcctgc caactcctcg gtcacaagtc acaatattca
    34861 acaaacatga gaagctgttt tttgaaattg ttccttgtga ctcggagcta aacggcaggc
    34921 tcacaacctc ttggtaaacg gtgttcaatc agctgaccct cggtattagc tcaaaaaacg
    34981 gcaaaatatg aggaactatt ttttccgttt ttttctctaa tactcaggtc aaaacgctga
    35041 tttcacaacc tctgattcac ggtgttccag aagtagcttc tacggaaata agccgaaatt
    35101 tcacaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa gctgaccact
    35161 tctgtcacaa cctcttattt tgattagaac ttgcgaaaat aaaccggtta aagtgtgtct
    35221 agcgcaagag atttgctata atagacgata agggtaaaat gtaacgagaa ggggttgaaa
    35281 aatgtgtatc aaattgtaac agattcttgt tgtgatctgc cataccatgt attagcaaaa
    35341 gaaaaagttg attttttatc aatgaatctc caattgaatg atcaagagtt agtagatgac
    35401 ctcggaaaga cattcaatta tgaccgctac atgaatcagc tgaaaaatgg tgcgatgcct
    35461 acgacatcac aaatcaatgt tggccgatat ttagaatttt tccgttctta tgcggaaaaa
    35521 cagattcctg ttttatatgt ggctttttcc agtggattaa gcggctctta cagtagtgcg
    35581 cttcaagcgg ttgaattgct gaaggaagaa tatgaagacc ctgagatcta tgtttttgat
    35641 acaaaagctg caagtattgg ggaagggctt ttagtattgg aagctgtaag attgaaaaaa
    35701 gaaggtaaaa gcatcgaaga aaccctagag tggctggaaa gtaattattt gaaagtccat
    35761 tcatgggtaa cagtagacga tctgaaatat ctagaacgag gcggtaggat ttccaaagca
    35821 agtgctactc ttggcagtct attgagtgta aagcctatta ttacggtgga taaagaagga
    35881 aggctgacga atgttgacaa agttcgagga agaaacaagt cgatccagac aatcgtcaat
    35941 gagacggtaa aaacaatcgt tgcaccactt gatcaaatcg tttatgtggc ttacgctggg
    36001 gatctagaga gcgcggagaa ggcaaaacgg cttttggaag agcagataaa gatgaaagat
    36061 gtgaagcttt atcccttagg accaacgatc gccagtcaca caggctatgg ctgtatcgcg
    36121 attttttcga tgggaatcag tcgataaaag cagtaactca ttctgtaaaa aagcccagaa
    36181 attgattgta acaaaaacag cgactcttaa aagatagatg agcatcctat ctcttagagg
    36241 tcgctgtttt tttatttttt aagctaaata ggccattatg cccataactc gttcaattgt
    36301 ttttgaatat ctgcattttc caaaaattca tcatatgtcg tatcagctcg atcgatcaca
    36361 cctttatccg aaacggcaat gatgcggttt gccaatgttt ggataaattg atggtcatgt
    36421 gacgcaaata agattgagcc agtaaatgcc atcaagccgt cattcaatgc tgtgattgat
    36481 tctaagtcta aatggttcgt tggatcatct aatacaagta cgttagcttt cgaaagcatc
    36541 atttttgaaa gcatgcaacg gactttctct ccaccagata aaacattcac tggtttcaat
    36601 acttcttcac cagaaaacaa cattcttcct aagaagcttc ttaagaaggt gttatcatct
    36661 tcttctttac ttgcatattg acgcaaccag tctaaaatcg ttagatcagt atcgaattct
    36721 ttcgttgtat cctttggtaa ataagaatta cttgttgtca caccccaacg tactgttcca
    36781 gtatctggcg taatttcacc catgataact ttgaatagcg ttgttgttgt tatatcattt
    36841 tctgcgacga aagcgacctt gtcttctttg ctcaaattaa aagatatatc atctaaaatt
    36901 ttctttccat caatcgttac acttacattt tctacctgca ataagtcgtt tccaatctca
    36961 cgttcaggtt tgaatccaac gaatggataa cgtctagaag aaggttggat atcgtctaaa
    37021 gtaatttttt caagcatttt tttacgtgaa gttgcttgtt ttgattttga tgcattcgca
    37081 ctaaagcggg caataaattc ttggagttct ttgatttgtt cttctttttt ggcatttgcg
    37141 tttgcttgaa gtttagccgc tagttgacta gattccaacc aaaaatcata atttcctaca
    37201 taaagtttga ttttaccaaa atctagatcc gccatatgtg tacatacttt gttcaaaaag
    37261 tgacggtcat gggatacaac gatcacagta ttttcaaaat tgatcaaaaa ttcttccagc
    37321 caattgatcg attggatatc cagaccgttt gttggttcgt ctagcaaaag aacatcaggt
    37381 ttaccaaata gtgtttgtgc taataacact tttacctttt gtccaccagt taattcactc
    37441 atttgctgat ggtgcaattc ttcagggatg ttcagacctt gcagtaaaac agctgcttct
    37501 ggttcagctt cccatccatt aagctcagca aattctcctt ctaattcagc tgctcgaata
    37561 ccatcttcgt cagtgaaatc ctctttcatg taaatcgcat ctttttcttt cagcacttca
    37621 tacagacgct tgtgtcccat gatgactgtt tcaagtacag tatagtcttc atagtcgtaa
    37681 tggttctgtt tcaatacggc catccgttca tctggtccca tagtaacgga acctgtggaa
    37741 ggctgcagat cccctgataa cactttaagg aacgttgatt tacctgcacc atttgcacca
    37801 atcaagccat agcagtttcc gggggtaaat ttaatattca catcatcaaa tagtttgcgg
    37861 tctgaaaagt gcaaactcac atcatttaca gtaatcaatt tttttcctca cttttatcat
    37921 tattagtttt gacaagtctt atagaattat ataggggaaa ggtaaaagat tcaaggcaat
    37981 cgaacattct ttgtgtttca cgtgaaacag aatgaaaaaa ataaaaataa aagcggagcg
    38041 aaaatagcta ctataggatt tattagtttg caacagcata atttttgacg ttatttataa
    38101 gagggagtac tataaaactg taaaagaaat gaaagaagga ttgaaaatgg atgaaaaaag
    38161 aaccatcgac tggggctcat tgattttggg aattttattt gtacttgtct cattgttatc
    38221 atttcaagac cctgtcggaa atttagttgc aattgtagta gtctttgcga tttttgcctt
    38281 tattaaaggg atatttgaac tgtttgtacg gaacagatta aaagagctaa caggatataa
    38341 aggaaagatg cccttaataa tcgggatcat cgatattcta gttggcgtct ttttcttatt
    38401 caatattggt gcaggagtcg cagcattgcc ttttgttttt gcagtatggt ttattgctga
    38461 ttcagtttta gcgttattta ctgctgactt ggcaagagga gtaagtgaag gatattattg
    38521 gtttacgatc atcgtcaata ttttaggaat tttattagga attttcttat tgtttaatcc
    38581 aatttcttct gcgttgacat taagcttttt agttggattc tattttatgt tatttggtat
    38641 cacacatatc gtctatgcat ttagataagt aaaatcaaac aaataaaaaa gccggcttcc
    38701 gattacagtt ttactgttgt aattggaagc cggctttttt atcatggaca aatatgcacg
    38761 aggtgatttt taggtgtcga gacaaattta tgcaaaaatg tgagaagcta tatacacaaa
    38821 ttttatctta atactcgaag catagcgcag ttgtcacaac ctcttttcat ataattcatt
    38881 caatactggc aaatcatgga cttcatattt ttctttgaat gcttggattt cttcttcaga
    38941 atattttctt ggatctaaat gcagatcttc tactggcaat gggcgcttgt tattgatctt
    39001 cacatcgatt actacaggac gatctgattt tgcagctgca tcaaaggcaa atcgaagttg
    39061 cgagtattct gtgactgtaa agctatttgc cccgagcgct tctccaactt taccgaaatc
    39121 tgcatcttct aaaaatacac caaatttctt ttgttccgta tcttcttgtt ctgcttcgat
    39181 gaaaccaaaa gaatcattcg aaaagacaac attaataatt ggaagctgat atttgacttg
    39241 tgtaatgata tcttgcatga ccatagcaaa cccgccatca ccacttaagg taaatacttg
    39301 tttttctggg tagcttagtt gtgcggcaat tcctcctggc acaccattac ccatagttgc
    39361 gaaccatcca gatgtcgtat gtttttgttt accgttcata ttcaataaac gaatagaatg
    39421 gatagtcgtg ttaccgacat ctgtgacgaa aatcgcatcg tcttcagcaa tacgattgat
    39481 ttctttatag acagcctctg gacgaatcgg ttcttcctct cgatcttcaa aagatttcaa
    39541 ccaatttacc catttttctt tattttcttg atttgctagg taccagctat cagcagggcg
    39601 agcatcccct aactcgacaa gtctttgcaa agctgtgttt gcatcaccga ggatcgacaa
    39661 agatgtttca tggcgtcgtc caaattttga cgcatcgata tcgatttgga taaattcagc
    39721 agttggatta aaaaatgcac gtccaaatgg gaagtcgcta ccgacaaata agatcagatc
    39781 ggcttctgcc aatgcttcat ttccgggttt agtagcgaca cgtccagcaa aaccaagaaa
    39841 gttttcataa tcatcaggaa taattccttt tgctagaacg gaagcgacaa caggaactga
    39901 aaaatgttct gagaattctt tgatttgcgg aaatccgttt cgcgttcctt gaccaacata
    39961 aagaactggt ttttttgctt tttcaagata aggcaaagca gctagcaaat ctttttcttc
    40021 tggtaatatc acacttgttt tgtgagtgtg agcggtggag aaaggttgtt cgtcaatttc
    40081 ttcaaaacca agatcaacag ggatagtcac gatagccacg cctttatgct cataggcggc
    40141 tttaatggct tcatctacta catgcggaag actttgtggt gtcatgactg tacgattgta
    40201 tacgctaaca tctgcgaaaa taggattttc atttagttcc tggaaagagt tatagttcat
    40261 ggatgtagaa gcaacttgtc ctaagaacgc tactagaggc acatggtcca tctgtgcatc
    40321 atacaaacca ttgatcaaat gtgtcgcacc aggtcctgca gagccgaaga cagcgccgac
    40381 tttccccgtt aattttgcat ctgcagcggc tgcgagtgcg ccgacttctt catgacgaac
    40441 ttgaatgtag ttgatttcgg ttttttcttg atatagcgca tccataattg aattgaaaga
    40501 tcctccggga atgccgtaaa tatggtcgat accccagctt tcaagaactt ttaccattgc
    40561 gattcctgca ttgatttttg acatggtgtt tcactccttt agcaatgatg atacataaat
    40621 tttttgtatc tagagtatag aactttttat cgaaaatccc aactaattcg tcttttcaca
    40681 aaaatgtagt catgtttttg ggaatatgct agagtagtac atagatagat tcaagagagg
    40741 ggaatggcat ggttgaatgg ctattgagac ttgaaccttg gcagcaagca cttgctggga
    40801 cagcttttac ttattttatg acagctcttg gtgccgggtt ggtttttttc tttaaagaaa
    40861 tcaaaaaaga agtgctaaac ttgatgttag gatttgcttc tggtgtcatg attgctgcaa
    40921 gtttttggtc tttgttagat ccggctatta caaaagcaga agaaaatgga gatattgctt
    40981 ggctagttgt aagtattggg tttggtttag gcggtgtgtt tttatatatg gcagataaaa
    41041 cactgcccca tatgcatttt ggaccacaac atgaagcaga aggattgcct acccatttaa
    41101 aacggacgat cttgcttgtt ttttctatta cattgcataa cattcctgaa ggtttagccg
    41161 tgggggtagc attcggtgca gcagcaactg cggataatcc gacagccgct atattagccg
    41221 ctgtttcggt ggcgctaggt attggtatcc aaaacttccc agaaggagca gctgtatcaa
    41281 tcccgttgcg acaagaaggt ctgagtcgta aaaaggcctt tgtttacgga caagcttctg
    41341 gaatcgttga accaattgct ggagtgattg gagcgctact agtaacgaaa gtggagctgc
    41401 tgcttcctta tgcacttgct tttgccgcag gagcaatgat ttatgtcgtg gtggaagaat
    41461 tgatccctga agcacagcag acattgtcca gcaaacatca ttttgcagtt tttggcgtca
    41521 tgagtggatt tatcattatg atgattttgg atgtggcatt aggataaata aaaaaaatat
    41581 atatgatata tcaaataggg ccgcgaactt atatcgcgac cctatttttt tagtaagtta
    41641 tatcataatg aagtgaatgg tatcatacat taataatagt tttttctatg tgtatttcct
    41701 ttgatccagc gaacaagcca gatgataagt gcgattggga ttagaacttt gaccgcaaac
    41761 cataaaagcc cgcttaggac actgacaaaa agactgatga cgaagctagc tgcaattagc
    41821 actaaaagaa ccatgaagat atttaagaac atattttttt gacgcataca aaaccctcct
    41881 cttgttcatt ctttactata gaaaaagtat aacagggatt gtttaaaaac acctccaact
    41941 gaagactgat ttttacttca tctacttaaa tgatcaaaca attgcttttt ctctggttta
    42001 tcatctaaaa tagagcggaa aaggaggaga atatcatgcc taaaaatcgt cttgaagcat
    42061 ttacagatgc tgtaatcgcg attatcatga ctattttagt tttagaactt catgaaccta
    42121 acggagacac gtgggaggcg ctcgctgcat taggttaccg attttttatc tatattgtca
    42181 gttttatcat tttagcgatt tattggaaca atcatcatca tttatttcaa gttgtacata
    42241 agataaatgg acgggtctta tgggcgaaca gtttctttgt ttttgcgctt tcgctttttc
    42301 cgtttgcaac ttcatggatc agtgagtaca tcaatagcct ggctccagaa atgacttatg
    42361 gttttgttac cttgaccgct aatattgcgt attatatctt ggcaaaagaa cttgtcaaag
    42421 caaataaagg ccacgagaaa gcattgaagg cgatgttgaa taattacaag aaatcgtatc
    42481 tatcgattgg tttgaatgtg ttaggaattg tcttagggta tttagtagcg ccagtagccg
    42541 tgctgatcgc aaacatcgtg attctagctg cttggatcat cccaagtcgt accatcgaat
    42601 cacaatatcg gtaaaatgat ccgtgtttaa aatttaagag aaaaatatag aaaaaataaa
    42661 taaacgatca aatatccgag tgatactagt attcaaagag ggatgcagat ggatcaaaaa
    42721 agaattcatg taggactgat tactagtttt gtcacgatgc ttatttattt ggatcaaggt
    42781 catttgactt ggacagtagt tggtgtcgta ggatttttga cattattcac agcaataaaa
    42841 aaataaacat ctttatgtaa tctgatgttc tatctattta agaaaagcat gtttacagca
    42901 gtatgattct gttgtaaacg tgtttttatt tgtggaaaat ttaattttta gaaaagtgta
    42961 t
//
LOCUS       DACBYO010000015        40618 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.015, whole genome shotgun sequence.
ACCESSION   DACBYO010000015 DACBYO010000000
VERSION     DACBYO010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40618
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.015"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(115..1392)
                     /locus_tag="IVD26_000783"
     CDS             complement(115..1392)
                     /locus_tag="IVD26_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078783.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(1471..2115)
                     /gene="pcp"
                     /locus_tag="IVD26_000784"
     CDS             complement(1471..2115)
                     /gene="pcp"
                     /locus_tag="IVD26_000784"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAP6078784.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(2314..3258)
                     /locus_tag="IVD26_000785"
     CDS             complement(2314..3258)
                     /locus_tag="IVD26_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAP6078785.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(3260..3946)
                     /locus_tag="IVD26_000786"
     CDS             complement(3260..3946)
                     /locus_tag="IVD26_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAP6078786.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            4420..4740
                     /locus_tag="IVD26_000787"
     CDS             4420..4740
                     /locus_tag="IVD26_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAP6078787.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            4894..5799
                     /locus_tag="IVD26_000788"
     CDS             4894..5799
                     /locus_tag="IVD26_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6078788.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            5796..6569
                     /locus_tag="IVD26_000789"
     CDS             5796..6569
                     /locus_tag="IVD26_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP6078789.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(6750..8174)
                     /locus_tag="IVD26_000790"
     CDS             complement(6750..8174)
                     /locus_tag="IVD26_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6078790.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            8385..8831
                     /gene="nrdI"
                     /locus_tag="IVD26_000791"
     CDS             8385..8831
                     /gene="nrdI"
                     /locus_tag="IVD26_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAP6078791.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(8896..10878)
                     /locus_tag="IVD26_000792"
     CDS             complement(8896..10878)
                     /locus_tag="IVD26_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6078792.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(10892..11788)
                     /gene="murQ"
                     /locus_tag="IVD26_000793"
     CDS             complement(10892..11788)
                     /gene="murQ"
                     /locus_tag="IVD26_000793"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAP6078793.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(11791..12852)
                     /locus_tag="IVD26_000794"
     CDS             complement(11791..12852)
                     /locus_tag="IVD26_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP6078794.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(13063..13590)
                     /locus_tag="IVD26_000795"
     CDS             complement(13063..13590)
                     /locus_tag="IVD26_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP6078795.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(13657..15159)
                     /locus_tag="IVD26_000796"
     CDS             complement(13657..15159)
                     /locus_tag="IVD26_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAP6078796.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(15417..16538)
                     /locus_tag="IVD26_000797"
     CDS             complement(15417..16538)
                     /locus_tag="IVD26_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP6078797.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            16664..17605
                     /locus_tag="IVD26_000798"
     CDS             16664..17605
                     /locus_tag="IVD26_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP6078798.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(17755..18651)
                     /locus_tag="IVD26_000799"
     CDS             complement(17755..18651)
                     /locus_tag="IVD26_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAP6078799.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            18920..20260
                     /locus_tag="IVD26_000800"
     CDS             18920..20260
                     /locus_tag="IVD26_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6078800.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            20478..20921
                     /locus_tag="IVD26_000801"
     CDS             20478..20921
                     /locus_tag="IVD26_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAP6078801.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(21425..22843)
                     /gene="nhaC"
                     /locus_tag="IVD26_000802"
     CDS             complement(21425..22843)
                     /gene="nhaC"
                     /locus_tag="IVD26_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAP6078802.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(23246..24469)
                     /locus_tag="IVD26_000803"
     CDS             complement(23246..24469)
                     /locus_tag="IVD26_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAP6078803.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(24500..25339)
                     /locus_tag="IVD26_000804"
     CDS             complement(24500..25339)
                     /locus_tag="IVD26_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAP6078804.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(25356..26036)
                     /locus_tag="IVD26_000805"
     CDS             complement(25356..26036)
                     /locus_tag="IVD26_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6078805.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(26038..27111)
                     /locus_tag="IVD26_000806"
     CDS             complement(26038..27111)
                     /locus_tag="IVD26_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6078806.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     gene            complement(27758..28429)
                     /locus_tag="IVD26_000807"
     CDS             complement(27758..28429)
                     /locus_tag="IVD26_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP6078807.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(28516..31194)
                     /gene="mgtA"
                     /locus_tag="IVD26_000808"
     CDS             complement(28516..31194)
                     /gene="mgtA"
                     /locus_tag="IVD26_000808"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAP6078808.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            31853..32290
                     /gene="ndk"
                     /locus_tag="IVD26_000809"
     CDS             31853..32290
                     /gene="ndk"
                     /locus_tag="IVD26_000809"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAP6078809.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(32312..33178)
                     /locus_tag="IVD26_000810"
     CDS             complement(32312..33178)
                     /locus_tag="IVD26_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6078810.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(33338..35431)
                     /locus_tag="IVD26_000811"
     CDS             complement(33338..35431)
                     /locus_tag="IVD26_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP6078811.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(36180..36803)
                     /locus_tag="IVD26_000812"
     CDS             complement(36180..36803)
                     /locus_tag="IVD26_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078812.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(36962..38359)
                     /locus_tag="IVD26_000813"
     CDS             complement(36962..38359)
                     /locus_tag="IVD26_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP6078813.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(38391..39362)
                     /locus_tag="IVD26_000814"
     CDS             complement(38391..39362)
                     /locus_tag="IVD26_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6078814.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            39736..40161
                     /locus_tag="IVD26_000815"
     CDS             39736..40161
                     /locus_tag="IVD26_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078815.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT        11750 a         8502 c         7095 g        13271 t
ORIGIN      
        1 tagtcctcaa ggctttgttc gaactttctt tcactcttca ctataatcta aaaatagaaa
       61 atagaggaga acatcattcg tcaatgatgt tcccctctaa tcttagtatg ttttttatag
      121 taattccttc agatactttc ttgcctcatc attgaaacgc agtgattctt ctaacttctg
      181 ataatattcc aacgcttgtt tctgagcttc agtaaaacga taatgttttc ctttccattt
      241 gtcgattgtc tcttgcacat ttccagattg gatatctttc actactagtt gccatttttc
      301 ttttgagact gtacggtctt tcttatcagc agattgtata gcttctcgtt ctttacgcaa
      361 tacttttaaa aaaccatttc tgactatccg aggaatgctg tcgaagaacc cttctgtaaa
      421 accatagcga caatattgct tccaaataaa tagatagatt tttggttgga tgaatcgttg
      481 gtttttcgca aaatattcca tctgagcagt gacttctggt gttcgttgac gttttgtctt
      541 tctcaacacg gaaataaatg tttcaaaata agcattagga tgtactggca cttcttcata
      601 tacgatggat tgccaatctt tacgtaaaaa tgcgcgatag ttgatcaaga attcttctac
      661 atcctttact aattcttctg caaagtcgtc aaatagttct ttttttatct gtcgcttttt
      721 tgactgccca ttgatgtgtt cacttatttt cttgatttca ttttccaatg cttgataatc
      781 cgctatgtaa atcggcattt ctacttggcg aaattctgcg agccgctgag ctaattttat
      841 atccggtaaa tatggctgtt tcatccgacg attttggtac aagacaaaac agtatttttg
      901 ccatagtcct tcaggaaaat cgatattctt ctgcttaagc cataataatt cgtctaaggc
      961 cagatcaact tttgtcattc cctgatggat cgaagctgcc actgtcggag agacatgcag
     1021 gtgatcggca aagtggttga tgcctagttt taggatcttt ccggtttttg gcgatttaac
     1081 gatgtattgc acttttaatt ctctaccaca ctcacaatac aatttttgct ggcttcgttt
     1141 tgttcgaaaa aacggattga tcttgaagtc agaaaacacc caatctgttg cagctaaata
     1201 atgttcttcc ataaaacgag agctgattag atatcggcgg tgcttatcga ctagttcccg
     1261 ctgttttttc gttaattttg catagatctc ccaacgttga ctgcttgtgt attgtttaga
     1321 aattttgatg ggatagcttt tgctgatttc ttttggaaac cattcttcaa agacggattg
     1381 ccattcttcc acggctgttt ctttcctttc taattacaaa aagctggcta ctaacataac
     1441 gttagcaacc agccagtgtt tcttgctaaa ttagtgagtt gttccggcat ttccggaaat
     1501 atcttcttta ttttctactg ctgcttcaac tgcataagtc aaagaagaag caatgtcttc
     1561 taaagacata gaaggcgtac ccactggacg atcgatcact tgatcgggtg agaatggcac
     1621 gtggatgaac ccacctcgaa ttgccgggaa ttgtgtttcg atcaaatgaa gcaaacgata
     1681 catgatatca ttgcagacaa atgttcctgc tgtataagag atgtacgctg gtagaccatg
     1741 atcttgtaca ttttttgtca ttgctttgat tggcaatgag gtaaagtaag cggctggacc
     1801 gttttcttct aaagccgtat cgaatggctg atttccttca ttatcaggga ttcttgcttc
     1861 tgctagattg attgcgacac gttcgaacga gactgctgac cgcccacctg cttgtccgac
     1921 acagatcacg acatctggtt ggtgctgttg gatggcttct ttgactactt gactgctttt
     1981 ttcgaatacg gtcggtactt ccactttgat gatttcagca ccgctgattt catctggcat
     2041 tttttttact gcttcatagg ctggattcac tttgtcccca ccaaatggat caaaacctgt
     2101 tactagtact ttcatctgtt gttcctccgt ccgattgatt taacatatgg ttatctttta
     2161 tcataccatt ttccttgaac agcgtaaata aaggaaacaa tagtttaaat aacataacag
     2221 atcaaactta atatattctt ataaaaaaat agtgttccac tacaatgtta gaagaggttg
     2281 cgacaattat tctgtcacaa cccctctctt ctattattta aatagaatca tataagcaat
     2341 ttggaaaact agcataaata acgcaataaa caactggttt ttgatcactc cgtatttgtc
     2401 tttcatctcc agcatcgcta caggcacgat attgaagtta gcagccatcg gtgtcagcag
     2461 ggtcccacaa aaaccgcaag tcaatgcaac cattcctatt aacgctggat tcgctccatg
     2521 actaaatacg aatggtgcac cgatcccaac cgtcatcacg gtgatggccg caaatgcatt
     2581 ccccatgatt accgtaaata tcaccatgcc aagagcgtaa atgatgatgc cgatgttcac
     2641 atttccttct ggaacgatcg tacctactgc attggaaatc actgtcccaa ctccagcgct
     2701 tgtaaatacc gcacctagag aagctaaaag cattggcaac atgcttaacg gccctactgt
     2761 gcccagcata tctgctgcat catctaaaaa tgtacttggt cgattatctc gagaaaagaa
     2821 catcaagatt agcatggctg caaaaacacc gacgcccacg ccgactaaag cacctaaatt
     2881 ggtaaataga gcaaacaaga tcgcaaagac accgatactc aaagctggaa taaaaatttt
     2941 cattcctagt ttgtctgaca ttttttccat atattctttt gatggaagcc ggctttctcc
     3001 tttgctgact ttcttagcaa ttgctggtat ggtcatcgca aagatcaagc caccgttcac
     3061 gattgccgga agccatcttc ctcctgcaat aactacccct aagaccgtcc agaaaaaggc
     3121 tgacccataa cgatgaggat tggttttatc tgttaaattt cttactccag tgtaaatcaa
     3181 tacgagtccc atcacgatat aaaggatctc cagtaattta tcgcctaata aaatatcagg
     3241 atttgtaaaa aagtccatct tattgcccct ttcctggata atatttcttc gctaatttct
     3301 tttctttaag atagaagtag acacttgcca caactaaagc cgtgatagcc actggaactt
     3361 ccactaaagc aagctgtccc aatgttacgt catatcctag atctttcagt gttgattgga
     3421 ctagcaacgc ccctgctcct ccgatgaata gtacttggcc aaagaaccag cagacatttt
     3481 ccatagctga agccatacct tttagttctt cttcatgctt aggatggact tctaaccctt
     3541 ttgattcgat ggtccccaat gccatcggta aaatgattgg acgaacaaat ccagcaactc
     3601 caccaaaact cacgttaaaa gccgcaaaga tcattcgaaa gatcccataa atatctacaa
     3661 tcataccagc agatactttc ttgaatcgct tgatcaagga agccgctgat tctttcagac
     3721 catttctttc aagcgttcct gttgccaaca taatgatgat aaaaatcgcc atcccgcgat
     3781 tgtttacaaa acttgtacct aaaagttcta acattccttg aatgccaaga ccgccagtca
     3841 aagctgtaac aactaaagca accattacga tcaatatcga gtctaattta aatgcaaacc
     3901 cgagaataac aatcaagacg cctaaaaggc taagataatt ttccatatat tttcctccat
     3961 aaaatgacaa tattttttta attataaagc aaaacacata aaaaatatag ttgttttctc
     4021 acgaaataga cactattttt aaatattttt cgttattttt ttatcacaaa aattatctta
     4081 cttattgtaa ggtaaagctt tttttaattt attgcccgat aatatataga aataaggtct
     4141 agttactgtt ttttttaaat gattaataaa taacaacttc tttctatgaa attgcaaagc
     4201 attcatcttc ttttccgcta acgatatatc cgtcagtgct tggtacactt tactaaaaag
     4261 tatgagattg ccgatatctg gataggtgtg ctatactaca gaaaaagata tacaatctgc
     4321 caccgggtag gataaagagg atgatcattc cattaggtct ttgaagggat gattttcctc
     4381 tttttgtgta tttttttata gttaaggagg aatgtaagta tggcatggat ggaattaatc
     4441 atagcaggaa ttttggaagt attctggtca acgatgatga aatggagtga tggtttttct
     4501 aaaatcaatt attcttttta cacagtgatt ggcatgattg ctagttttta ctttttgtca
     4561 aaggcaatca aaagtttgcc gatgagtctc tcttatccta tctggacagg gattggcgca
     4621 gttggttcgg tcataattgg tgtggtcttg tttcatgata agctgaatct ttccacttgg
     4681 ttctttgtgg ggatgctact catcagtatc attggcatca agattactag cggccactag
     4741 acacttggaa taagtactga tcagaaaaaa taagcctttt tatttaatat tcaatttttt
     4801 tatgaaaaaa taagaaataa gtccaatgac ctagcgactt ctccactcat caggtgtatg
     4861 cttgtactat ctatagaaaa ggagtgaata tttttgaaaa gtctttcggt ccaagaatta
     4921 tccaagaact ttggtcacaa acaagccctc agcgatgtca gttttagctt atcccctggc
     4981 aaaatcgttg gattagtagg tcctaatggc gctggaaaaa caacgatcat gaaagctatt
     5041 ttaggactga tccattactc agatggaaca atctgtattg gtgaaaatga gatttctccc
     5101 tctagtcata aagggttgga acaagtagga gcattgatcg aatacccggg tatctatcca
     5161 ttcttaacag gctatgatca tctgaagtta ttctctgaaa ccaacgatgt atctgctatc
     5221 gacactatcg tgaatcagct caagatggaa aagtacattc acaaaaaagc gaaatcctac
     5281 tcgttgggaa tgaaacaaaa attgggaatt gctcttgcct tactgaacca tccgtctatc
     5341 gttattttag atgagccgat gaacggtttg gatccacaag caacaagaga tgtgcgaaaa
     5401 atcattaccg acttggctac tcagggcacc tctttcttga tctccagtca cttactcagc
     5461 gagcttgaaa aaatggtcga tgagctgatc ctgatcaatc aaggaaagat catcaaacaa
     5521 tgtacaatgg ctgaattgaa ccaaacagcg caagatttca tcgttatctc tacaacaaat
     5581 gatctagctg ctcgaacgat cttgacagaa gctggatata ctttggaaga tcctgataaa
     5641 atcaagcttt taaaagaaaa cgaagaatta ttaggaaccg tgatccagct attgtctgca
     5701 caaaatatcc atgtgacaga cgtccagcat ctgacgaatg atttggaatc ttctctattg
     5761 gaaattctgg attcagtaaa gggggaagaa gaaaaatgac attgcttgta aaacaagaat
     5821 tatttaaatt gatcaagaaa aagtcaactg ctgttttatc tgttctatta gttgttttgc
     5881 tcataggaac agcacttcta gccaaaaaat acacgacgat cattgatcca gttgaaatga
     5941 ctgctcagct ttttagtgcc acatcttgga ttgtctttat catgattgca gctgcaagca
     6001 cgatcatttc gatggaagca caatatggta cattgaaaaa tctcctttat cgaaagtatt
     6061 ctcgaggaga aatattagta agcaaatgga tcacattagt tatttattct gtttatttat
     6121 accttttagc tattattgtc actgtgttga tgaaactgat tcttttccct tcgatttcct
     6181 tcacggagaa ggtttctact ggtcaaacac tgatccaaag cttgttcact tatactttgg
     6241 gtagttatat cggtttatgg ctgattttaa gtttagtgtt gatgattgct tgctttatca
     6301 atagttccgg cgcatccatc tcagcaggaa tcgtctttta ttttgcttcg tcaatcatat
     6361 ctggtatcct tattgcactc atccaaaaat gggagtggat caaatggaat ccgatcagta
     6421 tgttgaatct gcaaaaccaa attggaaacg aagagatcat gaagcaattg actcatcttt
     6481 ctactaatca aatgctattc ggtaatttag cttacatcgt tttgttctta gcattaggat
     6541 atctcgtatt taagcgaaaa aatgtatgat gactcatcaa aaaagaggct gtgaaagaga
     6601 cgttcagcct tattgccgat tggctgtctc ttaaacaccg tttattctga aaaaggagct
     6661 gtgacaacat ttgtgtcaca gctcctttcc tagtatgttt ttgaataaac gacaggctca
     6721 caacctctct ttatacttct tttatacttc tatacgtgaa gcatcccagt ggcaaataaa
     6781 accattgcaa tcactccgac catcgtcaca cctataagta aaatcttatc taagtggata
     6841 tgttgtacag gctcgttttg ctccttacgt gctttgaggt aaaaataaat gcctggcaag
     6901 aaaagaacaa gaacaagcat tacttcatta aaggctacga ctagcatagc ccatacttga
     6961 aaggcacttg ctaaaagccc tactaaaaat tggacccatt ctttccgctg ataagaaagt
     7021 ttcatttggt acaatcctaa gaaaagccac gtgaagaaaa tagctgctgt accaagtgtg
     7081 taagcaaagt tataagcact gtcagtgaat aataatgaaa gtaaaaagac attcgtacat
     7141 aacgtcgtca atacgatagc ataagttggt gccccatttt tgttgagttt tccccatgct
     7201 ttaggcaaaa gtccgtcttc agccatgttt cccattgttt caatcggtaa gatcgtccat
     7261 gagagccaaa caccaactaa agaaatgatc aaaccgccgt tgatcacgac tgctccccat
     7321 ttaccaacca tcatttcaaa cacatagccc atagcaggct gcgccttgat cgtttgcagc
     7381 tgattcatcg tcattgtccc atatggaagc atggaaacca agacgtaaat aataatcaag
     7441 ccgaatatcc ctagaatcgt tgctttccca acatctgatt gtttttttgc tcgtgaacct
     7501 acgacagagg ctccttcaat accaacaaat acccaaagca tcaccatgat gcaactcaat
     7561 acttgactgg aaaacgggat cggctgtcca ttcgcattca atataatgtc gctagaaaag
     7621 ttatcaatga attgttggat cgaaaacgtg ctgatagcta ctacaataaa taaaaataat
     7681 ggcactaatt tacagaatgt gacgatagca ttgacgaaac tagcattttc gactccccga
     7741 ttcactagcc atgcatatcc ccataaaaag actgtactca tcacgatcga tgccagattt
     7801 tgcccacctt caaatactgg gaagaaatat cctaatgcgc tcatcaacaa tgttgcaaaa
     7861 gctacgttgc ctaaccagca tgtgagccag taaccccaac cgctgataaa accagcgaaa
     7921 cggccaaaac cttcttctgc gtaactaaag atcccgcctt ttaaatctgg acgtttttta
     7981 ttgatattat tgatcgacaa ggagagcatc aacattgctg ttcctacgag tacccaactg
     8041 aaaatagctg ggccgccagc cgatccggag atgtccgtca taataccaaa tacgccacct
     8101 ccaatcgctg aaccaattac taaggcagca agtggaatta aaccaattcc ttttttctgt
     8161 tgctctgtat ccatgtaagc atcctccaaa ataaaaccgc ttttatcaaa aagtataaca
     8221 aacctttttt atttttactt aattaataaa aactttaata gaaatataat tctaccggct
     8281 tttttctcat tatacaagca aagcgcctag tccctttcca aattacacca ccaaaaaact
     8341 taaaaaagat gctatactaa aaggaaagaa ttggaggatg atccatgaac attttatata
     8401 tatcgatttc aggaaatacg cgtgcctttg ccaaacatct agcagaatat gctgaaaaaa
     8461 tgcatgcaga agatcctgtc aatcctgaag ttactttaaa agaaatccat gaaaatagtg
     8521 attttacgaa agaaacagaa ccatttttta ctttcgttcc tacttattta gacggcggaa
     8581 atggtttaga taacggtgat acagaaatct tgaccgaaac gatgcgtgaa tatctggaac
     8641 atgaagacaa tcataaactt tgtcttggtg tagtcggtag cggaaataaa aacttcaata
     8701 atcagtattg tctaacagcc aaacaatatg cacaaacatt tggctttcct ttcttggcag
     8761 attatgaatt acggggaaca ccatctgatg tgacacgaat ttatcagatt ttagcagaaa
     8821 acaataaata ataaaaaaga agaagctgaa aaatagattt cagtttcttc tttcgtttct
     8881 attgtttcta tcatattaag ctttgacatc catcacaggt gcttttgctt ttgctttacc
     8941 tgttttttcc aagacaaagt tttttacacg atccatattg gttaccaaga cgatcatgga
     9001 tgtttctttg cctgctgctt tgatcgcttc taagtcagct tctgctacaa gcgtatcagg
     9061 tgtcacttgc tgcccttctg ttactttcac atcaaatggc gtaccgccta agtcaactgt
     9121 gttgattccc atatgaagca agatttctaa accatttggc gttgtgatcc caatagcgtg
     9181 tttcgttggg aagacagagc tgactacccc agtaactgga gaatagatat gtccgttttc
     9241 tggttctaca aagtagcctt cacccatcat cttttgtgca aaaactggat cacttgcttt
     9301 atctaaagaa acaactgttc cgtcagcaac tgatgagagg atagtcacac tttcagctga
     9361 agtttgaggt actacttttt caggcacttc atttactgtg gctgtttcag tcgctaattc
     9421 ttctttttct aaacggtctt taggaatacc gaagaagaat gtagcaacga agccaccagc
     9481 ataagctgcc aataatccaa ggatgtagcc taaccattta ccgtcagaga tcaatgggat
     9541 caaagcggct cctgaaggtc caatagcgat agccccgaca tttccgatca ttccgatcac
     9601 tgccccgccg atacctccac cgatacaagc agtaataaat gggcgtccta gaggtaatgt
     9661 tactccgtaa atcaatggtt cgccgattcc taggatcccg actggtaaag ctcctttgat
     9721 catttctgtt aattctttat cttttttgca gcgaatccat aatgccaatg ctgcacccac
     9781 ttgtcctgca ccagccatcg caagaattgg aagcaatagc gtacgaccag tttcatcaat
     9841 catttgcaca tggattggag tcaaaatttg atgcagtccg aacataacca tcggcaagaa
     9901 taatgtgcct agaacgaagc cggcaaatgc tccaccaacg ccaagtaccc agttgatccc
     9961 accgaccatg ccatcagaaa tgaaacctgc taaaggcatg atgaagaaaa tttcaatcag
    10021 accgatggca atcaatgaaa gagttggtgt aacgatgata tctaccgcat caggtactac
    10081 tttatgcagt tttttctcaa cgattgacaa tagccaaaca gcgaagatga cacctaggat
    10141 cccaccttgt ccagctgcaa gagcttcacc agtaaataag tttttcagtg gtgcttccgg
    10201 attcatccct gtcagcatca caacggcccc gataactcca ccaagagttg gtgttgcacc
    10261 aaaaacttgt gcagcattga tacctgtata gataactagg tagctaaaca tcccgttttt
    10321 caagatgttc atcacatcga tatattgttg ccatgttgct gcatcaagtg ttccggctgt
    10381 gactaagttt gctaaaactg cggcaatccc tgccacgatc ccagtaccga caaatgcagg
    10441 aatcattggc acaaagatat tagaaatgtc ttttaatacc gatttgattt tagatggttt
    10501 ttgtttcgat ttttgtgccg ctttcatttc ttgtgcccgt tcgtttacac ggtcttttcc
    10561 agatgctgat gaatttgctg tagctgtact tacagaagaa agtttttctc ctaatttcac
    10621 gcctgccaaa tcaaccattt gctgtgctac tttgttcact ttcccaggtc cgatgatgac
    10681 ttgaagctgt tcatcttcta ctacaccaag cactcctgga atcgctttta attcagagac
    10741 atttacaaga tcatcattga tgatcttcat acgcacacga gtcatgcagt ggacaatgct
    10801 ttctacattg cccatgccgc ctgccccttt ataaatttgt tttgccagtt cttccaaagt
    10861 cagttcgttt tttgccatgg tcttttcccc ctcataaggt cccttttaca aatccgtttg
    10921 cttcagctaa ttttgcttga gcttcctctt tatcactatt tgtcaaaatc atgacgatag
    10981 ccagcttaac attttgatct gcttcttcaa agtacttttc agctgtttcg taatcagctt
    11041 ctgtcgcttg catgatgatt cgttttgagc gttcgattag tttttcattt gttggtttga
    11101 catcgaccat caagttattg aatactttac ctataccaat catactgata gtagaaatca
    11161 tattcaagat aagtttttgt gctgttcctg acttcaatcg agtagagcct gtcaaaaatt
    11221 ctggacctgc atcgacttcg attgggaaat ccgcgtgttt actgatttcg gcttgtttat
    11281 tgcaagaaat cgttcctgtg acagcaccga tcgattttgc gtaatctaat ccaccgatca
    11341 catatggtgt acgaccgcta gctgcgatac caataactat atcatttttt gtcaaattca
    11401 gcttgattag atcttcttgc cctagctcat aagaatcttc ggccccttcg acagctacag
    11461 tcattgcttc ttctccacca gcaattagac ctatgaccat ttccggttct acaccgaatg
    11521 tcggtacgca ttcagcagca tctaacacac ctagtcttcc acttgttccg gctcccatat
    11581 aaatcagacg tccacctttt ttaaaggact caatcgtgtt agcaatcact ggttcgatac
    11641 ttgtcagttc tttttcaacc gcagcggcca ctttctgatc ttctttgttc attagttgaa
    11701 cggcttgaga aatactcatc tcatctaatc caaaagtttc ttggtttctg cgttccgttg
    11761 ttaggttctc taaattgatt ttgctcattt ttatcttcct tcttttctta taaattgata
    11821 gttcatacca gctttgattt ggttgatcaa tggtagctct tctttgataa ctttagctac
    11881 tacattcact ttttcatccg ctggcaaatc atatttggtt aattggatct cacccatata
    11941 gcgcaaatac ttttcgttat ctaaagtaat agaccctttc atacgcgtag ctgtatttct
    12001 tgctgggata ggcggaatct ctcgaaaacg tgcatctacg cttcgtatga catctcttgc
    12061 atcgtcttgc cgattcgtat gcttccctaa tatatattcg taaaattctt catctacagg
    12121 ttccgtatgg agcaagactg tctgttcttt ttggaaagaa gcaaattgct cctgaacgtt
    12181 ttctgacaga cctgcatctc cgatgtaaac aatatccgtg ttacttgcta atagatctag
    12241 agcgcctgca agaggatgga tccctcgatg ttcttccaaa gttggcaatc cttgatatag
    12301 tgggcctctc aactctgtat ctcctggtac aaaaccttgg acaaggagac cttgaatttt
    12361 gagccattga ttttttttct gataccattc tttgtccagc cctgtttcgg gacgtggata
    12421 ataattatgc caagcttcaa tctgtgagaa atcagcttct gcttctttca attcatcgat
    12481 atctttaggc gtgatcgtgc tagcattcaa actgattttc aattgatgtg accagtcggc
    12541 aatctgctga ttggaaatat gataatccat tcttaaacct gttacaccaa ttgctttcaa
    12601 aggcgttaga tcttctaatg aaaaacccgc tcgttccaat gcctctcctg aaatatcgac
    12661 catcaattct agtttattct ttttcgcttc gcttcctagt tcgatcaatc gcttttgata
    12721 tgccgaaaca tcatcttctg gtatatgcat ggaagtgaaa ataccgacaa agccattgga
    12781 tgccatttgg cggatatact gtttcttctc ttctgacaaa gaatcgttca taaatattga
    12841 aaagccaaac atattatccc tctttttctg tatccgtctt catttctatg actagagtat
    12901 atatctaaag aaacaaaatt tcaatacttt tattaaaata attaaatttc atttctaaag
    12961 gttgagttta tattatcaaa agaattgtca taacctaaaa aaggcactgc taagcaaaag
    13021 cagtgccttg aaatatttta tttaaataac acaaaaacat aattactcat aagaaaccaa
    13081 ttctgtatta tctaccatga atgtaaagaa cccctcatta ggcatcggat gaaaataagc
    13141 attgatcact cttatcaagg cattatggca aactaacaga tagacatttt cttcgtcttc
    13201 gatgcattct ttcaataaag gaacgatccg tgcatacaca tctaagactg actccccatt
    13261 tgggaatcgt acagcgaacg ctaaacgtgc tttttgaaag ttctcatctt tgcttggcag
    13321 tccatcataa tccccaaaat ccatttctac caatcgttca tcaacggtca gcggcaagct
    13381 gagacgatca gcaactgctt gtgctgtatc tcttgctcgt tgaagagggg aatggatgat
    13441 tttcgtgatt ggaacaggca aatctactac cttttctgct agtttctgtg cctgcatctg
    13501 tcctttttca gtcagcggca catctgcccg tccgcaaact aatccttgtg cgttccaagt
    13561 tgtttctccg tgtctcgtta cataaagcat gtgattctct ccttcgttgg caaagttccc
    13621 cttaaccata ccttgttgtt cttgagatta caagggttag attctctcaa gagaaataat
    13681 ctcagtagat actttatcca ggaaggtttg atcatgttcc actagtaaca tggcaggttt
    13741 cacgttcaag atcagttgtt ctaattgttc ttgattgaag acatccaaat aattcaatgg
    13801 ttcatcccat gtatatagtt cagctggctg tgataaagat ttagccaatt ccactttttt
    13861 ccgttggccc atactcatct gctcgatctt gttatgaaaa acatctcttt ccatcccaag
    13921 ctttcggagg ttgttcaaaa atgcttggta gtctacttgg tttttctctg caaattccgc
    13981 caacgttcct cgattgtctt cataattttg gcttgcataa ctaatgctca gatgttttgg
    14041 ctggtatttt tctcctataa ccttgccgtt gaatgccccc agaagataat ggataatgga
    14101 tgactttcct gcaccgttag gacctgaaat cgccacccgc tgatgaggct cgattgtaaa
    14161 atgaattggc tcgaataaca gattttcata ccctaattga agatcttcta cgcttaaaag
    14221 tcgcttatgg tgagacgctt ggctattcat cgtcaaagaa tcgatatatt cgatatcttt
    14281 taatagtttt tctttctcgc tgatctgggt ctccatccga ttcacgattg ctttggatcg
    14341 tttcatcgtc cgtgcagcat cagcacccac tgctccttta ttcactcgtc tagattcagt
    14401 atcgatgaat ccgacttgtt tctttgtttt atctccttct cgggaacgag accattcggc
    14461 tttttcagct gctgttttct ttagcctact gacttctttt ttcaattttt cattttgagc
    14521 catttcaaat tcatcacgaa gttttttctg ttcttcatag atagagaaat tcccttgata
    14581 aagttccagt tgactttttt cgattgctaa aacatggtcc actacttcat cgataaatcc
    14641 ccggtcatgg ctgaccacga tgaagccttg ttttttcttt ttcaaataag ccgctacttg
    14701 ttttctacca gagatatcca aatgattcgt tggttcatcg attaacggga aatgagtgtc
    14761 atccacaaat aaaagtgcca gtaggacttt tgtcttctct ccccccgata gtgtgctgaa
    14821 ttctctccat aagatttcag gatctgtttg catcaattgg agctctcttt cgatttccca
    14881 tatctcaaaa tccgtaatat catttaacac gtaataggtt aaacgttctt tatcttttgt
    14941 ctgttgcggg aaataggcaa attcttgctg atggattact tgcccttgat aaggtagttt
    15001 gttttgtaga atattcagta aagttgtctt tcctcgaccg tttcgtccga taagtcctag
    15061 tttccattgt gtgtcaaaat ttagatttgc ttgttcaaat aataatgtgc cttggctgtc
    15121 gtagccgaat gtcagatttt ttatttcgat tttagacatt ttccatcacc tcgtaaaaaa
    15181 agaccagtcc tattttcaga actggctaaa gaggatgcaa gggttggata cacacaaaaa
    15241 gacccataca tcgaaaaaac caagccaatc ccgaaaatct gcacactgct tccttgtctc
    15301 cacaaggtac agtctgaatg cagctttcat caatcgactt aatttttcaa tgcacggatc
    15361 cctcactttg tcctatattt gaaattacga tagcataaag aaaatgattt tgtcaactac
    15421 ttcgggagga tggtgaaaaa tctgctaagt gtctgtccta agatttttgt tttttctaat
    15481 gtttgcctgt gttccattgc ttcttctaaa cctattggac ccaaatgaat acttaagaca
    15541 attgggagaa aatcagaaag tccttctagc tcttggtctc tacttccgca aatagcgatt
    15601 attggttttc gatatttttt tgcaagcact gctacaccgt atggaacttt tccgtggatc
    15661 gtttgctgat cgatccgccc ttctcctgta atgatgacat ctgcttgttc gatctttttt
    15721 tccaatccag tgatttggct gactaaatcg aaaccagaaa ccatcttcgc tcccaacaaa
    15781 aaaagggctc caccaatacc gcctgctgct ccacttcctg gaatatcatc taaatccacc
    15841 tcccagaaat cttttatttg ctgagcaatc tttcctgctt gtttatctaa gaaagctagc
    15901 gtcgtatcta ttcctccttt ttgtcttcca aattgccaag cagctccttg ttgacctgta
    15961 tatggattgg taacatctgc agcgataatc aattttactt tagaaacaag aacgtttctt
    16021 cgatcaaaat gaagtttttt agtagataat aaaggatttc cttctgtgta cccttctaaa
    16081 gaagcaccca aggattggag taatcctaga ccaccatcgc tacacccgct tcctcctaaa
    16141 gtgacaataa tttgttctac ttcttgaagc agtgcatctt taataagttc tcctaaggca
    16201 taactggaag caagtcggat agtttgatcc gttggtttat caagtagatc taaccccaat
    16261 gcttgtgcag attcgatgac tgcggtgttt tttccttgcc aagttgtcaa taaatagctg
    16321 atttttcgct gacggaataa gagatccatc ccatcaatgg tacgccatgt tcccctgagc
    16381 gcgtaataga ttgcttctgc agtattttct ccgccatctg caatcggcac attgattttt
    16441 cttcctttac gatcttccca gccatttaga actgcctgat ttagttcaaa tgaagaagca
    16501 cttcctttaa atgaatcaat tgccgccaaa atatccatct gtatccctca ctttcttctt
    16561 aagtaagaca ctttttttca tttttttcaa acaaaacaat gctattttct tccatttttc
    16621 tatatactaa aagggaactc attgaataaa ggagagaaaa aacatgaaaa tcgcaatagc
    16681 tggggccgga gcaatgggca gccgaatcgg attgatgcta catcaaagcg gaaatgaggt
    16741 cctcttgatc gatcgttggc ctgctcacat tgaagccatt cgtacaaatg ggttgattgc
    16801 tgactttaac ggtaaagaag tggtcgcaaa actgccaatc tattcaccag aagaaatcat
    16861 cgaaagcaac gaacacgtgg acttgatcgt agcattaaca aaagccaatc aattagatga
    16921 tatgttttgt tcgatccaat ccattattac tgacaatact tatgttttgt gtttactaaa
    16981 tggattaggt catgaagatg tactggaaaa atatgtgcca aagaaaaata tcttatttgg
    17041 gatcacgatg tggacagctg gtctagctgg tcccggaaaa gtcacattgt taggtgatgg
    17101 agaaatcgaa ctagagaact tggaaccaga aggcgaagca tttacaaaaa aagttgtaga
    17161 agtctttcaa gaagcaaatt taaatccgat ctatagccat aacgttcgtt attccatttg
    17221 gcgaaaagct tgtgtaaatg gaacattgaa tggtttatgc acgattttgg attgtaatat
    17281 tgctgaacta ggcgcgcaaa aagcggcaga gagcatggtt cgaacaatcg tatctgaatt
    17341 tgcttctatc gcagcaaaag aaggaatcat actagatcaa gaagaagtgt accaacatat
    17401 tgcttctact tatgatcctg acaacatcgg gttgcattac ccatctatgt accaagacct
    17461 gatcaaaaac catcgtttga ctgaaatcga ctacatcaat ggtgccattt ggcgaaaagg
    17521 acaaaaatat gatattgcta caccatattg tgcctttttg acccaattag tccatgcaaa
    17581 agaaggaatc cttggcgcag aataaaaggc tctctgatga gaatcagctg aatcagcagc
    17641 tggttctctt tttttaagcc caataaaaga tcaaaaagaa aacacaactc tcatgatgcc
    17701 ataagaattg tgcttgtttg tttcagtaca taatctcttc aaaatgtagg ttttttattt
    17761 gttttcaaca gaggagaggt catattcgta ttgctcataa atagtggaat cgttagtgat
    17821 aaatcgtttt gcccaatttt ctgcatcata aaattccaat agctctgata ggattggctt
    17881 aaatggtgta tgcagaaatt ccggtaattc atctaaatca cgttctcgaa gcaaaaaaat
    17941 attttcagga cgataaaaat gataatgagc aatcgcttga ttatccgtca ctagtttctt
    18001 ttgaaaatac atggattcaa atgtccgcaa agtcactcct tgctgaccct cccgcaacag
    18061 ttccagaatc ccgcgcgatt cccctgtttt tttcaggtac tcttcataag taagatatcc
    18121 aggttgttca ttccctcgat gtggaagaat gaaatagttg gtcgtaacat ctctttttat
    18181 aaattcctgc ttatagcttt ctgctcgttc ttttctccca ttattcgttg caccaaaaaa
    18241 tagatccgtc tttggttcgc tagaagaaaa attcatatgt ttcgaataaa atgaactatt
    18301 atgtttcagc ccaagttctt ttgcttccaa aaaatcaaaa tgataaatct catcgattgc
    18361 cggttcatct tgtgcctgct tcagcatcgc ctcgtgttct gctttgaagt gattccaaaa
    18421 aaataacaca atttttgcat tggtaaatgg gcgcacgcgt cgagccatct ccatatcaaa
    18481 tccataatct aaaaaaacga tcagctgata atttgccaac tgttgtctag ctgatttaat
    18541 gaattccgac tgtagtaaat cttttccgga ccaaacatct aaagagcgga tggaaggcaa
    18601 aaaataaagt gatttatttt ttgcaactag cagtacgtca tttttgttca tcttttccgc
    18661 ctcactttct ctgtcacttt ttcctatgat agcctgttta aatagtaaaa agccagtaaa
    18721 acgtttccta tatttgtatg aaaatttaac atttgtatga aaatatgatg aaataaatca
    18781 ttcttctatt aaaattcgcc taaaagtttt ctgaatagtt gtaattgtct gaaaattttt
    18841 tatcattagt cattgttaaa tattgctatt tattcttaat ataaattttg attgtgaatt
    18901 taaaagaaag aggtcattta tggaagataa aaaattgaaa aaacaactta gctccagaca
    18961 tatcaccatg ttagctttag gtggagcaat cggtgcaggt ctatttaaag gaagtggcga
    19021 agcgattggg atcgccggcc cttctgtatt gattgctttt ttgattggtg ggctgatttt
    19081 atatatcgtg atgaaaggtc tgggaaaaat cgttttaagc ggtggcgaca cgcatcacgg
    19141 attatctggt ttgatacgcc cttatctagg tgctcattct gctgatttta ctgattgggt
    19201 ctactggtct atgtggatta tcaatatcat cgctgaagct gttgcagctg cttccttttt
    19261 gcagttgtgg ttcccgcaca ttccagcctg ggtatttgtt tttatgttgg ctgttttaac
    19321 tacgatcatc aatctttatt cggtacggtt attcgcagaa acagaatatt ggctggcttt
    19381 tgctaaaatc agtgtcatta tcttactgat catttttgct acttatcttg tcggtcagca
    19441 aatgttgggc acaggcgttt tccctaccct tcagcaattg actgaccatg gtgggtttac
    19501 tcctcatggt atgaagggaa tcatcagttc tttgcttgta gttatctatt cttacggcgg
    19561 ttctgaactg attgctatca cggtaagcga agcagatgat cctaaacgtg cgattcctaa
    19621 agcaatcaaa ggtgtcatgg gaagaatcat ttccttttac atcattcctt tgtttttgct
    19681 tttgattctt tttccttgga atactttagc aggcacgaat gtcagtcctt ttgtgatggt
    19741 atttgaaaaa atgaatatcc catttgcagc ggatatcgtc aattttgtga ttgtccttgc
    19801 tttgttctca tctatcaatt cgggtgtgta tgcatcttca agaattttgt tcttccgttt
    19861 gaaggatcga aaaggttcct ctagaaaact agctgtttta aacaagcatc aagtaccgca
    19921 acgtgctgtt ttattttgta ccagtgttct ttatcttggt gtagctcttt cttattttgt
    19981 cggtgacaaa ttatttggct atctggcagg ttccctttcg tatacagtat tattgatctg
    20041 gatcattatc agtgcggcat cctttgtact ggcactaaga aaaggaacat tatgggataa
    20101 aggaatcagc ttttttgcat tagctgtctt aggattgatt ttccttggta tcctgttcac
    20161 gaactccatt ggggtaactg tattgactgg cctgctttac ctgttcattt atttcagtta
    20221 tcaaaaaaag aatgatgcgt tcgtattgac gaatgaatga aatcgataga aaattttatt
    20281 ttatttatgt ggaatagatg gagctattga agaaaggagt tgtgacaaaa gtcttgttgc
    20341 aactcctttt tccgaataaa cagtctcatg acctcttggt aaacggtgtt caaaaaccct
    20401 ctgtgcaaaa taattgattg ttctccatgc tcatgacatg atagaagaaa ggaatgaaaa
    20461 aaaggagttt gttttaaatg aaaaagtatt ggaagttttt gttgatgatc ggtgtttcaa
    20521 cggtagttat gtttggtatg atgtacttga atgtctatgc gctcgatcat atcttcttca
    20581 gtcgtacacg agtattcatg gcgttgatga tgggtgcagt catggcagtc atcatgctgt
    20641 tgttcatgtg gaaaatgtat gaaaacaaaa agataaatgt tatgatctta gccgctagtc
    20701 ttcttgtttt tgccggttcc ttgtttatgg tacgaagcca aactactgtc aacgacacag
    20761 cttggatgaa ggccatgatt cctcatcatt ctatcgctat cctggcaagt aaacgagctg
    20821 atttaaaaga tcctgaagta aaaaaattag cggaagaaat cattcaggca caagaagaag
    20881 agatcgacaa aatgaaaaaa atgatcaaag aaatggaatg accattatcc gtccaaataa
    20941 aaaaagagga tgttccagaa gttatcagct tcaagaaata agaagaagct acttctggaa
    21001 cgccgtgaat aaggggttgt gaaaaagctg ccctgcatca agtaataaga acagccaaac
    21061 aaaaatagct tctcctattt ttcgtttggt taggcttatt accgcagatg caagcttttg
    21121 aacaccgttt attaagaggt tgtaaaatca gcgttctgac ctgagtatta gagagacaaa
    21181 tggaaaaata gttcctcata ttttgccatt ttttgagcta ataccgaggg tcagctgatt
    21241 gaacaccgtt tatcgagagg ttgtgaaaaa gtcgcttagt ttcgcgtatt aagaaaaatt
    21301 ttgtgaaatg gctttccaca tttttgtata aatttggctt aataccgaga aactggcttt
    21361 tgaataccgt ttattcgtaa aagggattgt gacaaaagtc ttgtcacaat ccctttttat
    21421 gtttttattg ttctaattgc gctgtcttgc ttactgcttc ttgcggtttc acaaattttt
    21481 ttgagattcc ccaacctgtg aaggcactga ccatcgaaaa cacaggagaa agcaaactga
    21541 aaaatacgaa tggcaagtaa gtgagtgtag gaataccaaa tgtacttgct acgaaacttc
    21601 cggcaattcc ccaaggcact aagtagttga ttactgttcc accatcttct agcgttctac
    21661 ctaatacagt tggatcaaat cctgcttttt cataagtttc tttaaatgca ttaccaggca
    21721 gaataacaga taggaattgt tcaccaataa aaatatttac tccgatactt gtcatcaatg
    21781 ttgtaaaaat caaatttggt gtgttcgtca tctttcttga tactcgttcc atcacggttg
    21841 agatcaagcc aaattcgatc aacaatccac ctaatgacaa agttagaata atcaatgaca
    21901 cagtaggcat catactttcg attcctccgc ggctaagcag tgaatcgatt tgttggtttc
    21961 cagtatttga aacaaaccct gattcgatga ccccagccaa cttcgttaag gaagtttgtg
    22021 ggttttgaat aaaaatcatt cctactgcta cagcgatatt caacaaaatc gttaaaattg
    22081 ccggcacctt tttccatgca cacagtaaca ttaaaaataa aggaatcagt gaccagattg
    22141 aaatagtaaa gtttgcttct agaacatcag tcacttcacg aatagatgaa agacttgcgg
    22201 ctttacttgt gtgtcctaaa atcatgaata aaaagaaaga aacaacaaat gccgggacag
    22261 ttgaccacat catatgcttg atgtgtttga acaaatcggc atcaacaata gctgctgcta
    22321 gatttgttga ttcggataat ggagacatct tatctccaaa aacggcacct gaaacaatag
    22381 ctccaacaac cagcgctgga tttaagccta gtgttgtccc aataccgaaa aatgcaatcc
    22441 caatcgttga cataacagta aaggcactcc ctacagcgct acctacgatt gcacacacaa
    22501 caaatacaga agggacaaac cactggacac tgatcaattt gaacccaatg accattagag
    22561 ttggaatgat ccctgcttgt atccatacag caatcaatga accgactaaa ataaaaataa
    22621 agattgggat gattcctggt ttgatgccat tgatgattcc ttcgtgcagc caatctgtcg
    22681 ggtatctttt tatcactgca tacaacatga ccattccgat cgctgctaag atcgtgatat
    22741 taggtgagac ctttaatccg acaacgccaa tcgcaatgcc taaaacaata accattaata
    22801 caagtgttgc ttctaaaaaa cttggtgttc ctttttttcc catgataatc tctccttttt
    22861 tagttgttct tatgttctaa aaaagttaag atatcggatt actccgccgc aattcatccg
    22921 cgattcctcc tttataaaaa taaaaagacc tgttttaaac taaggacgaa tgactccgcg
    22981 gtaccacctt aattaaaaac agatctgttt ttcactttca aacttttatt caaatgtatg
    23041 gactttccat gtaattcgtc aattaggctt gatcggttca cagcgaccac cgactttctg
    23101 aacaaaacac ctaaccgcta ctgcgtgaaa agttgacttg tacgaagttt accttccata
    23161 agatcatttg tcaatgaaaa agaaaatatt ttttcatttt tctgaaaatt atttttataa
    23221 ctttcacaca caagattatt ttttactaga aagtagcgcc ctcttgtttt tttcttgcta
    23281 ctatttcttg atgttcttgc ttgattcttt ctaatagctt tggctctttc aacagatcaa
    23341 gagctgtatt ggcgagtagt tctgctgcaa tcgcaataga agcaaggcct ttgtcacttt
    23401 tagcagcagc tttgaattct tctgtgtgtc cggcaatata tgtctcagag attgctaccg
    23461 taggctggat tgttggtatg acttggctga catttcctac atcagaagaa ccgagacttg
    23521 ttctttgttc cgtttctatt tcttcatctg gaacacctgc ttcttttgca tgctggaaga
    23581 ataagtcatc aaaagaagga gtaacgatga catcatcaac tgcattttgg aacaatccaa
    23641 actcaaaagt cgtgcccgta cttatcgcag cacctcgtac gatattttcc actttttcat
    23701 atactttatc taatgtttgc cgatttcctg cacgtaaata gaaacgtcca gcagcgtaat
    23761 ctggaatgac gttggcagct actcctccgt ctgtaatgat cccatggata ttgacatctt
    23821 ttggcaattg caagcgtaga gcgttgattc cattaaacac ttggatcaat gcttccaaag
    23881 catttactcc tttttcaggt gctgctgctg catgggaagc gacaccgtaa aatttgatgt
    23941 cgactggatc attcgctaaa gattctgtcg ttttcccata acgaaaagct ggatggacgc
    24001 ataacgctac atcgacatcc tcaaaaaaac cttctcgaac aaagctgcct ttagctgatc
    24061 cgttctcgcc cccttcttcc cctggggtgc catatacacg gatttctcca ccagtttcat
    24121 caatgaattg cttcactatg ctggcggcta atacggagta agtaccaaac aaattatgcc
    24181 cgcatgcatg accaatacct ggtaaagcat cgaattctgc caaaaaggca attgtgggac
    24241 cgggtttatt ggaaatataa cgtgcatcaa aggctgttcg gtgtccagct acttcttttt
    24301 ctacccaaaa cctttctttt tctaattgtt taatcaacgc tgctgaggaa taaaactcat
    24361 agttacttac ttcaggatgt tcgtggatat ctagagcaag tgcttgatat tctggtaaac
    24421 gatattggat tagatccttc aattggtttg ttgagattgt tgttgtcata aaaaattcct
    24481 cctatgctag tcatttttct tattttctcc cgaatgtttc ccatgcaggc acgcttgatc
    24541 cttttgatgt tttctcgatt actttgactg tgtcttctgt ttgataagcg tctactattt
    24601 tttgatacgt tttattgttt tcatcttctt ttcttgcaac gatgatattc acataaggac
    24661 gtgcatggtc atccactggt tctaagaaga tggcatcaga agcaggatta aatccagcat
    24721 ctacagctac accgctattg atcactgaaa tgtctacatc tgacaaagca cgtgctgttt
    24781 gggaagcatc taattcagaa atgtctagat tttttctatt ctcggtaata tcagaaacag
    24841 tgggcgcttg tccttttgcc ttatccactt tgatcaatcc agcagtttgc aataacagaa
    24901 gagctctgcc gccatttgta acatcattag ggattgctac ttttgctccg tctttgatat
    24961 cagctacatc cttcaaagtg ttagaataaa ttcccagcgg tgcattgaca gtatttccga
    25021 tcgatactaa atcagttccg tgttctttat tgtaattgtc taaaaagaat tgatgttgga
    25081 aagaattcaa atcaatcgat ccatctgcta aagccacatt tggttgattg taatctgtaa
    25141 atttcacgta ttccaaatta atgttctcct ttttcaaacg gtctttcacg ttgtcccata
    25201 catctgtatc ttctccaata atccctagtt ttacgatagt ttcttttttg tcagttgtat
    25261 ctgcttttcc ttggctacac cctgccaacc aaataattgc tacaaatgta atgactacaa
    25321 aacgaataat ttttttcatt ttttctcctc cactttcaat gtgtaatttt tttaatcagt
    25381 tgattactga taaattgact taaaaaaact aagattagaa tcaataatgt agccacaatc
    25441 gttacatctg tttggaatcg attataccct ctcgatatag caagattccc taatccgcct
    25501 gcacctactg ctccagccat ggtagtcagt ccgatcacgt tgatgatagt caacgccgag
    25561 acccgaatga taccaggcaa accttctaac aaatacacac gtaaaatgat accgattgga
    25621 ctggttccca tcgcttctgc cgcttcgatc accccaggat caacttctag cagtgcgttc
    25681 tcgatttgac gagcaaaaaa cggaacaact ccaaaaatca atggcactaa agctgctttc
    25741 gcaccaatcg tcgttccaac taagaaacga gtagtcaatg ctaaaagaga aagcaagata
    25801 atgaaaggga tggaacgaat gatattgatc agcttatcaa gtatttcaaa tagcagacgg
    25861 ttagctagta atccattagg gcgtgtcact actaacgtca cacctaagat gattccaatc
    25921 atcccgccaa tgaatgctgt ccaaaaagac atatatagtg tttgcttcgt cgcttcgaca
    25981 aattcatccg gaatcaaata aacattgggc aaatatgttt taaagaaatc agtcatttta
    26041 tcttcctcct tcgatcactt tgatacgact atctaaatcg tttttttgta aaatatttat
    26101 ttttacacca gatttgatca aataatccaa tgcttttttc cgctgtttgg tttctccagc
    26161 taaagtaacg atcaaactcc ctaacggcgt ttcttgtaat aactctacat tgccatataa
    26221 aatattcgct gttacttgat atttgctgta cagatgagcg attagaggtt cgttcgtctg
    26281 atttccaata taacttaatt ccaccagcca tttattggcg atctgatcgg caaaagcaga
    26341 atgggcaatg atcgtttcta atgcttggtc aagatgagta gctgttcgaa taaaatcttt
    26401 ggtcaattct tcttcaggat tgctgaagat ctggatgctg ctaccttttt caacgattct
    26461 tccatcttcc ataaccgcta ccttgttgca gatttctttg acaacttgca tctcatgagt
    26521 gatcaggacg attgttaaac ctaactggcg attcaatttt tttaacaatg caaggatctg
    26581 aagggtcgtt ttcggatcaa gtgcactggt tgcttcatca cataataata ccttaggttc
    26641 attcgccaaa gctcgtgcga ttgctactcg ttgtttttgt ccccccgaca gttgtttagg
    26701 ataagcagat gctttttctt ccaaaccgac aagttccagt agttcattca ctttttgacg
    26761 acgttcctgt ttcgattttc cagaatactt taaagaaaaa tcaacgttgt caaaaatagt
    26821 tcggctttcc attagattga aatgctgaaa gatcataccg atggcctttc tttcttttcg
    26881 caattctttg ggagagagct gactcagatt cgtctgattg acaatgactt ctcctgctgt
    26941 tggtttctgc agcaaattca tcacacgaac taacgtactt ttccctgcac ctgagtaacc
    27001 gacgattcca taaacatcgc ctttttcaat cgttaaatct acagaatcta ctgcctgtat
    27061 ctctttttct ttttgtttga aacatacaga aacatctcgc aattcaatca ttaaaattcc
    27121 tccttatcta aaaaaagcgt cctcaagaaa atgaaaatgt cattttcttg aggacgcttt
    27181 tttgcgtgtt accacctcat gttcaagctg tgttcacaca caactcctct tcaagtacga
    27241 tcatactcta gcaagatatc ggtcgcagcc gtcatcgcct tacatctatg ctcgggatga
    27301 attgctcgat ggccattttc caatagtcgt tccttgcttc ttctcagcta ccgaagctct
    27361 ctgtcaaagg ttcttctatc gtacttacca tttcaatgca aataatattc aaaaaaaaag
    27421 tccttttact aacataaact atgtcagtaa aaggacgacg tatcgcggta ccaccttttt
    27481 tcggaagttt ccttccctca agcccaacat ctcaaaaaga gagattggcg ttcgttttaa
    27541 cggtcgaaca gttccgaatt tgcctactta tcgacaaatt attctccaag gccattttca
    27601 gcttttctta cttgactctt ctcaccagcc agagcctctc tgcaaagttt ccaaacttac
    27661 tttccttttc aacgaaatcg atattttgtt gttgggatta atctacatga ggaaaactga
    27721 aaagtcaagt acgaaattca aattattttt tctatattta tttttctgtt tttttattta
    27781 acatttcaat aacagttcga agatcttttc cttccgcaag aagtttcaat ttttcctttt
    27841 cttcgacggt ataatttcgg acaaaactgg aatcaggtat caaaacaacg cctaatcctg
    27901 ctcgtgaagc agctgttgct cctactaaag aatcttccac tgcaaaggct gaactagctt
    27961 ctaatcctgt tcgttccaaa gctgtcagat aaggaatcgg tgaaggcttg ttctccgaca
    28021 cttcgtctcc gaatgtaaac gtgtccaagt aatcagctaa tttaaagtga tccaagatat
    28081 ctgttgctct tttcgtaaca gtggtcgtag caatgcctag tttcatatga cgttctttta
    28141 agtctgccaa tatttctttt gcatatggtt ttaagtggat ggctccgctt gtcagctgtt
    28201 gataaaaata ttcttcacgc ttcgctcgga cttcctgtac tttttcaggg ctacctgctg
    28261 ctttcactaa aatatcaaaa ctttgtttcc agttttttcc gccccaagcg tcaacgattt
    28321 cttttgggat atggatatca aattgctgaa atccccaaag ccagccatca cgatacgttt
    28381 tttctgtgtc aactaacaaa ccatctaaat caaatattgc acctttcatc tatacattaa
    28441 tcctttccaa aacaatacac atagtttagc acgactggtc caaaaagaac agaagcaaag
    28501 aaccagcctt ctcgtttata agagttcttg gaatcgacgg atatagattt tcttcacagc
    28561 tgtcacaagc gccagataag cgatgactgt agcaaataac cataaccagt aattgccagg
    28621 aagtggcatc aagcctaatt cagcaccaaa acttgtaaaa ggaaggacag aaccgacaat
    28681 aattcctaat gtagtgataa caaacatggc aaatgttgcg ttgctttgga taaatggtac
    28741 tttcggtgta cgcagtgcat ggagcactaa ggtttgtgtc catagtgatt cgacaaacca
    28801 tcctgcatgg aataatgcga tgaaaatcac tcgctgtgaa ctatccaatg tatggaaact
    28861 tccgcccact acagcaggac aaataacaaa atacatcaac aagtaagtag taatatcaaa
    28921 tatcgaactt gttggaccaa agtaaaccat gaattcccca atactagatg cattccattt
    28981 ttttggctcg tccaaatatt ctttatccat ccgatcccat ggcaaggaaa tgcaggaaac
    29041 atcatagatc agattcaaaa acaaaagttg taaaggcagc attggtaaaa atggcaggaa
    29101 cgtacttgca atcagcacgg aaaacatatt gccaaaatta gaacttgctg tagccttgat
    29161 atatttcatg atattcccaa aagtttctcg tccagaaaga aggcctcttt ccaaaatcgt
    29221 caaatctttt tctaaaagga tcacgtctgc agattctttc gcaatatcca cagctgtatc
    29281 tacagaaata ccgatatcag ccactttcat tgcaggagcg tcattgatac catctcctaa
    29341 aaatccgaca gtatgaccat ttttacgtaa agctgtcgtc aaacgtgctt tttgctgagg
    29401 attcaatttt acgaatactt catggtcttc agctacttgt gctaattcat gatcactcat
    29461 ttccgagatt ttctcaccgg taaccaattc attgatctct agacctactt gacggcacac
    29521 tgaacgtgta actaattcgt tgtccccagt cagaactttt acagctacac catgttcttt
    29581 cagagctttc aacgcttgtt tcgttgtttc ttttggtgga tcaaggaaag caagataacc
    29641 aatcaaaacc atgtctgact catctttgac tgaaaattct ccaacgacgc ttggattggt
    29701 cttttgtgcg acaccaatca ctcgtaagcc atcttcatta agtgactgta cttttgcaag
    29761 tacggcttct tttcgttctt ttgttaatgg tgtaacagta ccgccaagat caataaattt
    29821 agaaatgttc agcatttctt caatcgcacc ttttgtgatc atttgtgttt taccagctgg
    29881 atcagcaacc acaacactca tacgacgacg ttcaaaatca aaaggaattt catccacttt
    29941 ttgataattg atcttatctg tatctaaagt ttctgttgct tcatcaatga tagccacatc
    30001 taacaaattt ttcagccctg tttgatagta gctatttaga tacgcatggc gcaaaacacg
    30061 atcatcttca tttccttcac aatccatatg atattcaaga atgattttat cttgtgtcaa
    30121 tgtccccgtt ttatccgtac ataacacatc gattgcacca aagttctgga tggcattcaa
    30181 atttttgatc actgttcctt ttttggccat cacacttgct cctttgacca aattcgtcgt
    30241 aacgatcatt ggaagcattt caggtgttag accaactgct acagatagtc caaaaagaaa
    30301 agcttctagc caatcccctt ttgtaagccc attgatgacg ataactgctg gagccatcaa
    30361 tgacataaat ttgatcagta gcatggatgt tttatggatg cctaattcaa agcttgattg
    30421 aattggtttt tcagatagcg tttctgctac atgaccaaat agtgtttcat ttccaacaga
    30481 aacaatgatt ccttccgcac ttccactgat gacattactt cccataaaga caagattttc
    30541 gtaacttgtt tcgctttgct gatcgtcttc acatactttc gcatgctttt ctactggata
    30601 gctttcccct gtcaatgctg cttgggaaat gaataaatcc tttgcggaca ataaacgcat
    30661 atccgctggt atcatatccc ctgctgaaag ccgaacaaga tctccacaga cgatttcttc
    30721 cataggaatc tctgtgtact ttccattacg ttttacagct gccgttactt tcacaagtga
    30781 tttcagtttt tcagccgctt gattggaacg tacggactga atcaacgtca ttgtcccgct
    30841 gacgataacc atagtgaaga taatggctac accgaaaaga tctttatctc caggagctgc
    30901 taatacatat tccgtgatga atgaaataat tcctaatgcg atcaacacta atgtaaatgg
    30961 cgtgatgtat gctttcaata tttctacaat gaatggtgtt tttttgccat atgaaatcgc
    31021 attttcaccg taattttctc ttgaacgttc gatttgttct tctgtcaatc catttgctga
    31081 tgcatggaat agttcaaata attcttgttt cgtttttcca gcaaaagctg catagatttt
    31141 ttgtgtatct ttcttttttt ccatctcaat ctctcctttg tgtccaaaag acagctgttc
    31201 tcgctgcttt tggtctttag ctattcatcg gatcgataga gaaaaaactg aaaggggctg
    31261 agaacagata gataatagcc ctggcctttc ctctagatcc ttgtttttcg aatgactgtc
    31321 atccatttgt tctcatctcc tttactaagt aattttaatt catgacttcc aatcattttt
    31381 cgaatagtta tttttccaat tagaccacct cctttttatt tttcaccgat ggggatttgc
    31441 ggcaacaaaa aaacctctcg ccaaatactc agcgaaaggt ttgaaaaagc atattaaaaa
    31501 aagcttctca gatctcatcg ttgagttttg acactgtaca acgtaaaaag cagatacctg
    31561 cttttagcta ccttatgaaa agccttatct cgacaattcc tgttctaccc attggcgtct
    31621 ctcgacgttt ttgggcagta gcctatgttt gtataggagc ctcacctaac aaatcttatt
    31681 cggttttcct tcgttaatat aacaactaaa aaagaggatg tcaaatcaat tttccatgtt
    31741 tttcatactt tttttaaaat acacacgtta tattcctgtc tcacgcggtt ttatttgtct
    31801 cattttccac ctcccgctat aatagaaata tagtaggaaa cgaggtgctg ttatggaaag
    31861 aacacttgtt attatcaagc cagacggcgt gagacgccat ttagtcggaa gcatcatcca
    31921 acgttttgaa gcaaagggac tggccattgc tgaaatgaag tttgaaacta tgactcctga
    31981 attagcaaaa gaacattatc agcacttgac tgagcgcagt ttttttgatg aactgatcga
    32041 ttacatgact tccggtcctg tcgtttatct tgtgctggtc ggcgaggaag tgatcgatat
    32101 cgtccgtaag atggttggag caacaaaagc tgccgatgct gttccaggta cgatccgagg
    32161 agactacgcg ctgccgggga ctgaaaacat cattcacgct tctgattccc gtgatgctgc
    32221 ggtaaaagag atcgcccgct ttttcccgcc attcgatata aacaaaccgt ctgaaaaagc
    32281 ggcgaagtga tacaaattct aaactgctgg tctagttgct gggttcagca atggccagca
    32341 gttttttctc taaggacctc cgttgattct ttcctaacat atattcgagc actgtgaaga
    32401 attcttggta gtctttcgtc ttttcttccc ctaaagcagc agaaatcaat ctttgataat
    32461 aatctgccat caatgtttca tagatcactg tacttctttc tttatgtgct aagctccgtt
    32521 tcatatcttc attcacacta cgtgcctttt tcaaccgacc attttctata taaaacgaag
    32581 tcaggttcat taaaaaagta aagagatact gctcatgatt gttcaactgt gctaatcgtc
    32641 gcattctttt tttgattttc aaataattgt tctcaatgaa ccgatcactg aatatccaag
    32701 gaaaatcagc tagaatagat agttcaaatt gaccatagtc tggtatctgc atcaagtatt
    32761 cttcaatgat tcggcattca taacgtaaaa attcaaattc tgtctcagat acttctgttt
    32821 tttcgaccat gtgaagattc aaaaccaaat aatacagatc ttctgttttc ttaaaatgcc
    32881 tacggttatt gctgatctct ttataaggat caaagctgtc ttcttgtacc cgatctagca
    32941 ttcgtctttt tttctttaac tttattggtt catccagctg gtttcgcatc cattcatatt
    33001 ctgcaagtgt catgttcatt cgctctaaaa atgatctcaa tgttacaaat gacatttttt
    33061 tcactgaatt tgtctcaatc ccgactagag aagtcttaaa acagattcct tccgctaatt
    33121 gggactgtgt caacttcttg ttgactcgaa gtttcttgat caattcacca tcatacataa
    33181 tagttctcct ttttaattta aatttttcca cattcaataa atagatacgt taaaaaggaa
    33241 aaatacacga aaaaaataaa aaaatgtttt tttcataaaa aataccaacc ttcaagcatt
    33301 agaatgttgt ctaactactg aaggttggtt tgattgttta ttgattattt ttttgctgtt
    33361 caacgtctgt tcttgttact ggatataagt tggttgttgt tttattacca ttttttgaaa
    33421 agacacttgt cgaatgttcg cctttttgct tttcgattgc ttcattacgt tccgcttcat
    33481 ttttatagtc atattttttc ggatcaatcg tctcaaatcc gtttggcaca taaaaccgca
    33541 agagattttc ctgattcagc ttatctgaaa gacttaacgc agtcttgact ttttcctgat
    33601 ctttggagat ttcctcatcg attcctgctg ctttcgtatc gatgatttct cctgtctgat
    33661 tattgtaagc ttttcctcct aggacggtgt atttgggtgt cacaaagttc ccatttcgaa
    33721 aagcaactac ttgatcatgc tgagaagata ataagtctgt accaaaatga agataatctt
    33781 tatcatcgat tcccaataga tgtagtaatg tcggcaaaac atcgatttct ccaccgtatt
    33841 catgattgac tgtcccttta gtataaccag gcatatggat catcaatggc actcgttgca
    33901 tctgtgcgtt gtcaaattca tcccatgtat ctggatcttt accaagagcg cttgctaaat
    33961 ctttattatc tgtattcgag atcccaaaat gatccccgta aatcacaaag attgaatttt
    34021 ggtaaatacc agattttttc aaatacgtaa aaaattgttc caatgattga tccagataat
    34081 gtgccgttcg aacataatta tctactgtgc tattgccagt attcaaagat ggaaagtcga
    34141 aattcttgtc atccgtataa taaggcgtgt ggttggttac ggaaagaaat ttcgtgtaaa
    34201 acggctgttg tagatgctca agatattggg cagattctct gaataaatct ttatctaata
    34261 tcccataacc taacgtttcg tcggattcat caaaataaga tcgatcaaag aaattgtcat
    34321 aacctaagtt tttatataca tgatctctat tccaaaaact agctacattc ccatggaaaa
    34381 cagcgcttgt atagccttgc ttttgtccaa ggatcgctgg tgcggcttga aagacattgt
    34441 ctgacccaag ttctgtgaat aatgagcctt gaggtaaacc aaatgtgcca gtttccaaca
    34501 tattttcagc atcacttgtc tttccctgtc ctacttcatg aaagaaattg tcaaagctga
    34561 tcgttgcttg attctggaaa atactattta aaaacggtgt gacttcttgt ccgtctacct
    34621 tcatattaat caaaaactgc tggaaacttt ctaaatggag aacgatcaca tttttccctt
    34681 tagcgatccc aaatgtttcg ggatttggct ctgcataatg tttctttgta taatctaaaa
    34741 cttcatcaat cccattactg cttgcatgcg cgcgaacact gctagtcatt cctgttttga
    34801 ttccgtcata aatagtatac gcatcgattc ctagatattt gacaatatat gaacggtcaa
    34861 atgttcgctg cagcaattgt ggacggttgg cttcgctcag cgctagattt cctgaaaaaa
    34921 taagccctga aagacaggta acagcgatag ccatcggttt gccgacaggg ttgcttttga
    34981 taggtatttt cttgaccttc aaccaaacca gtagcccaat gaacacagcg atatccagcc
    35041 agtagatgac atcatggggc ttcatcaaag aaaaggagct tcctgacaat ccttgcgaca
    35101 ctttcgaaaa gcctaataca gatttgactg taatgaaatc tgtgaattcc cgataaaaaa
    35161 taatattcaa gtacaacaaa agcgtattta aaatatcaat gatcaaaaga atagctaacg
    35221 ctggctttgg ctttttaata tacaaagaaa ggccaaaaaa caataaggta gtcgcaattg
    35281 ggttgatcca caagataaag tactggatcg taccttccac acctaatgaa aaatctgcat
    35341 agtaggcaat gatcgtcttc agccagaaaa agaaaacagc tgtcaaaacg attgctaaac
    35401 gattttggca caatttttta agttgtgtca cgtatatcac ttctctctat tcacattttt
    35461 tcttattttg ctcctgaaaa atgaaaattt cctaaaaaag ttgttatctt aagatttttt
    35521 tattctttct aaagattatt ccgtccactt ttcacagcat aaaaccgctg cgatgtaagc
    35581 gattaaacta atgaagagat aaaagtcttg tggtgaccgc ttcactccac ggtattcaaa
    35641 agccagtttc tcggtattcg tacaaaaaaa gaggctgtga caaaattctt gtcgcagctc
    35701 cttatttctt gatgcaggac agctttttca caacttcttc cttaaacggt gttctcctgc
    35761 caactcctcg gccacaagtc acaatattta taaaacatga gaagctgttt tttgaaattg
    35821 ttccttgtgg ctcagagtta aacggcaggc tcaagacctc ttgatacacg gtgttcaatc
    35881 agctgaccct cggtattaga ttatgtcagg acgctaattt tacaacctct tggtaaacgg
    35941 tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat aaggagctat
    36001 tttttgaaat tgctccttgt ggctcagagt taaacggcag gctcaagacc tcttgataca
    36061 cggtgttcaa tcagctgacc ttcggtatta gctcaaaaaa cggcaaaata tgaggaacta
    36121 ttttgccgtt tgtttctcta atactcaggt caaaacgctg atttcacaac ctctgttttt
    36181 cattgtccat aggattgata ttgtccttgt gatgactcat tcgtaataat tgaggcttga
    36241 ttttcttcac ttcccgttat cgtttgtcca ctgccagaat ctgaaggact tgttcctgtc
    36301 gactcgtttt tttgagaaga gacagttgtt ttcttgactt gttcatttgt ctttttccat
    36361 tccgctaaac gatcggcgac cacttttttg tctacttttt cagaataagc ggtgatcact
    36421 tttccatttt tcaaacgggc tactttgtcg ccatcatgag tcaaaagcaa aacggtcaaa
    36481 tgcttgtctt taaattgata ttgtctgaga gaaatcgcac taagtacgtc atcgatatta
    36541 ataaattgat tttcttcttt tccttttggc aaataaatgt ccaattcgcc tttttcgtaa
    36601 ttggcagtta ttttatactc cgcccaccaa taagttgaga attctttttt gaaattatct
    36661 actgattctt tgcttgctac gattttttct gtttctttct gagcaagatc tgctgtcatt
    36721 tttcctgaaa atgctgcgga taaaataagc agtaagaaaa aaccgaataa ccaaaagaga
    36781 agaaacggtc tttttttcct catgctttcc tccactccta tttaattttg actattctat
    36841 tatatacaaa aaatgaaata gaaagacaaa aaagttgaaa aagatcgtaa ataattgaac
    36901 ttctttttca caaaatggta agaatggaga atttcacgca tttgctctca actattcttt
    36961 cttaagcctc aaatccgttt ttatctgata cgtctttgaa ccaatgaccc gattttttga
    37021 ttgttctttt tccatcttgt gctaagtcta ctgaaataaa gccatatcga ttcttatatg
    37081 cattggtcca cgaccagtta tccatacatg tccacatatg atagcctaaa caattggcac
    37141 cttcttgaat ggcttgatgg acatatttca gatgagattg gacaaattcg atccgataat
    37201 catcgtggat catgccatct tctttgataa atcgtgcttc gttttctaca cccataccgt
    37261 tttcagaaat aaagcagtcg atatttccat aatgatctcg tacattgatc aaaatatcat
    37321 agattccttg ttcatagatc tcccatccgc gataaggatt cattttacga ccaggcattt
    37381 cataattgtc gaaataatcc tcaggcattg gaccgttttt agtatcgatt ggtgtttctt
    37441 ttgcttttac ccggcgtggc tggtaataat tgatacctaa aagatctact gtattttctt
    37501 tgataaccgt caaatcctct gcatggatca caggcatgag atcaagttct tttactatct
    37561 caatcaattc acttggaaac tcgcctttta cagctggatc aaggaatgaa cgattgaaga
    37621 acgcatctgc tatttgcgct gctttaacat cttcagggtt tgattcgtct cttggatagc
    37681 ttggtgtcag attcaagatg ataccaataa caccaccttg ctccatttca tggtaagatt
    37741 tgatggctaa cgctgaagcc aacgcttcat gatagccaac ttggatcgct tttttcatat
    37801 ctgactcttc tggataatgc catcgatata aataacctgc ttcgactgga acgattggtt
    37861 cattatgagt aaaccatttt tttactttcg aaccaaacaa ttcaaaacaa cttttggcat
    37921 atttttcata ggcttcaacc gtttctcggt tcaaccatcc gcctttttct tgcagataca
    37981 tcggcatatc gaaatgatac agattcacaa agggttcgat accgttttca atcaactcat
    38041 caaaataacg atgatagaaa cgaacggctt cttcgttgat tgttccagat tcatcaggta
    38101 tcaaacggct ccattggata gatgttcgaa atgaattatg cccagtctgt ttcatcaact
    38161 gtacatcctc ttgatacttc gtataaactt gcgaggtttt ttcaggtcct acttgatcaa
    38221 agaacttttg cggttctttt ttgtaccaat aatcaaaaat gttctctcct tttccatcgc
    38281 ctgaaatcct tccttctgtt tgtgggccac ttgctgcaga accccaccaa aaatttgctg
    38341 gaaattgata ttttttcatc aaagcacctc tttttctttt ttagttcgtt ttagttgatt
    38401 ccatgtatga tattttccat cacaatcact ttttcatttt cttcctcttc ttttttgatt
    38461 cgttttaaca gctgttctgc tgctcgttcc ccgattttat ctgttggtgg cgtgatcgtg
    38521 attttcggaa ggatactcag atcgttttta tctaaataat catagtgact gaacgcaata
    38581 tccttcccga ttctgacacc ttcttgattg aaacattcga tggcaccaat cgacatattg
    38641 taattgctga caaaaatagc agttgcccct ttttctaata atgcttttgc cccgtaatag
    38701 ccgctttttc tagaatagtc tcctgtaaag acctctaatt ggatcgatgg atcattttgg
    38761 accgcttctt tggctcctgc taaacgttct cttgctacgt agtctgtttg agtggcagca
    38821 ataaatccga tttttttatg tccttgttca ccatgatgag cgatcacttt tgctacactt
    38881 tctcgatcat tcactaatat tgtatcaata cctgctggtc cttctggaca attcaatgcg
    38941 ataactggaa tactcatttt tgtgagcatt tcaaatccag accactcttc ttcggataag
    39001 aagacaatca gcccatcgat cacatgcttc atcaggtatt caattttttg ttcaattttt
    39061 tctggctgat cggcaaaccc gcttaataat aagctatacc cattttcttc agctactctt
    39121 tcgatccctg agacaacttc cgacccaaaa cggctggaaa tcccgtttat caaaagtcca
    39181 atagagaagc ttcgattatt cttcaaccct ttagcaatga tgttttcttt atagtccaac
    39241 gctgaaatcg cttctgctat ttttttcatg ttcttttcct tcagttgctg accattcaag
    39301 taacgggaaa ctgttcccac tgaaacacca gccatcttag ccacatcacg gatcgatgcc
    39361 atacattctc actcctgcca gttacatttg atttctcttt cttgttgttc gattatgatg
    39421 accgcattct ttgcatagtg ttgcttgtca tcaatatcca tataactaaa gtcttcagta
    39481 gagcaacttc ctctcactat taattatact taaacaagta tttgaaccgg ttcattttta
    39541 atatagcatt tttttaaaag attgcaacac ttttttaaaa cgctttctga aagtggcgga
    39601 ttttttgcct ttttaaaatt ttattctaaa atttactcta tttgtgggtg ttttgtgcgt
    39661 ttttctcttc catccgtttg aagttttaca ttccaatggt ataatttctt tatcctatca
    39721 aatgggggaa gtattttgaa gaaattaatc gtactattta ttttgtctgc gggacttttg
    39781 acattgactg gctgtgattt gtttggcggc tctgaccaat cctcggacga aacaaccgat
    39841 tcttctgtct taaaagcgga aaaagcagat accaccaaca gtgtatatac gctaaaagta
    39901 cgtaaagata tggatttatc cgcgggacag ttgacattta cagataaaaa aatggaatgg
    39961 acacgcacgt atcagacaca aggaactgat tcttctgaat catctgaaga aaaaacagtg
    40021 ctgacagata tcaagatcac taccaaagat gacgaatata ttatttcagg aaaagaaaat
    40081 aaaaaagaaa caacagtcat atttacaaaa atcggtaatt accgtttgaa ggatgaggat
    40141 ggcaacatct acagtctata gtgccgtctg ttggatcttc ttttgtttct ccccttcttt
    40201 tctgctatag taaagaagca agatgattgt aaaggagacg aaatggatga tcgatagtcc
    40261 tgattattgt acatgtaata acaacaaaaa tatccataca gaatttaatg accaaggaag
    40321 cttgagcata tgcgacaact gtcacaaact agtcaaagat tcatttaaaa catttgaatc
    40381 ttatcctgtt caaaattatg taaaaagtag aagaagataa acaaatccaa gcaaaactca
    40441 ctatggctga tttttatgaa cttcaaactc agcttcttcc tttgatcaag cttcatcagt
    40501 aaaacaaaca gtggatcatt tcagtttaca aatcaaagag taaagattta tttatttcaa
    40561 atatttgaat ataaaataac caaacgatag aaaggcttat tctacatcac gtagtaat
//
LOCUS       DACBYO010000016        39565 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.016, whole genome shotgun sequence.
ACCESSION   DACBYO010000016 DACBYO010000000
VERSION     DACBYO010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39565
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.016"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..1751
                     /locus_tag="IVD26_000816"
     CDS             <1..1751
                     /locus_tag="IVD26_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6078816.1"
                     /translation="FLHYRTHHEKKLIIRKEELSLQVQKGLLKIKEIPERLDRFMDSK
                     SQYLTFEPGFADVVWSQDPERNMQVYNDIEEKVTSLSETGVENIDLETLISKDVDAYF
                     QTYVKELTKSSIPKDLLPDEIWRLTNQLYDVAEKRLDRIYNEKARFAFALHLQSTLDR
                     VREGHMIVHPDLNNVRKNFKREFQVAIDLSTIIEEEEQVEIPFDEIGFISMFLSINLG
                     ESEPVKENKVDVLILMHGRQTASSMLEMAQELLGTKVGKAFNMPLVMEVQTMYEEVLQ
                     YVKNYQEHLTNGLLLLTDMGSLNTFSDLIYEETGIRTKAITMTSTMIVIEAIRMASVG
                     RSLEDIYQNIQLSFESIVRDQFKAEKSETLQRKKAVIVTCFTGEGVAAKLYQRIMPVI
                     NQNKVELIQMQFLERESFKKHIDALLEEYEIKAIAGTVDVDYQNIPFFSAYDVFDDEK
                     LNILKRIADDEIPTAKIVDSLAGSLSDVFSIDELIRSLQKTVQQIQTDLSIIVEPGVD
                     TGIVIHLAFMLDGLIKQESHRQFEKLSIFSKIYRLEMDIVRANLMALERKYQVKIPED
                     DIAFLTQMFLENKIKK"
     gene            1903..2220
                     /locus_tag="IVD26_000817"
     CDS             1903..2220
                     /locus_tag="IVD26_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6078817.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            2250..2570
                     /locus_tag="IVD26_000818"
     CDS             2250..2570
                     /locus_tag="IVD26_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP6078818.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            2678..4138
                     /locus_tag="IVD26_000819"
     CDS             2678..4138
                     /locus_tag="IVD26_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6078819.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            4206..4427
                     /locus_tag="IVD26_000820"
     CDS             4206..4427
                     /locus_tag="IVD26_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078820.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            4458..4640
                     /locus_tag="IVD26_000821"
     CDS             4458..4640
                     /locus_tag="IVD26_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAP6078821.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            4640..5053
                     /locus_tag="IVD26_000822"
     CDS             4640..5053
                     /locus_tag="IVD26_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAP6078822.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            5176..6357
                     /locus_tag="IVD26_000823"
     CDS             5176..6357
                     /locus_tag="IVD26_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6078823.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            6746..6819
                     /locus_tag="IVD26_000824"
     tRNA            6746..6819
                     /locus_tag="IVD26_000824"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6780..6782,aa:Arg,seq:cct)
     gene            complement(6888..8027)
                     /locus_tag="IVD26_000825"
     CDS             complement(6888..8027)
                     /locus_tag="IVD26_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6078824.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(8141..8725)
                     /locus_tag="IVD26_000826"
     CDS             complement(8141..8725)
                     /locus_tag="IVD26_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HAP6078825.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(8852..9283)
                     /locus_tag="IVD26_000827"
     CDS             complement(8852..9283)
                     /locus_tag="IVD26_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP6078826.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFTASHFEYSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(9301..9621)
                     /locus_tag="IVD26_000828"
     CDS             complement(9301..9621)
                     /locus_tag="IVD26_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6078827.1"
                     /translation="MITFERIKELAKKQGKSLNKVEEDLGYGKNVLYRLKNSNPSTER
                     LQEIADYFDVSVDYLLGREEKETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            complement(10053..10232)
                     /locus_tag="IVD26_000829"
     CDS             complement(10053..10232)
                     /locus_tag="IVD26_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078828.1"
                     /translation="MNKKTDEIAADLVVAWLNHESQVSTKGESISPKEIAQAYLDIHY
                     AVIYGQLPEDRKNDD"
     gene            10313..11059
                     /locus_tag="IVD26_000830"
     CDS             10313..11059
                     /locus_tag="IVD26_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAP6078829.1"
                     /translation="MNTPQIFSFEQHEVRTFLENDIPYFVANDVAKTLGYKNPSKATN
                     DHCKKSIETWGNDSLGRRQKFKVIPESDVYRLIIKSNLPSAEKFEAWVMEEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            11074..11277
                     /locus_tag="IVD26_000831"
     CDS             11074..11277
                     /locus_tag="IVD26_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6078830.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            11293..11613
                     /locus_tag="IVD26_000832"
     CDS             11293..11613
                     /locus_tag="IVD26_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HAP6078831.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRR"
     gene            complement(11805..12281)
                     /locus_tag="IVD26_000833"
     CDS             complement(11805..12281)
                     /locus_tag="IVD26_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078832.1"
                     /translation="MRKKLNYILTATLTIYIILFITLSFLSSIKKIPFITLNKNSILK
                     EFNNIDYIAFLKLFSVCVLISCVIIFIVAKTCWTMLNKNQRDVENIAIFLIKITSSIS
                     IIIPMTVTFSKEQFNVAATYLSFIALFSFVLPKRNKSNFDNKELDEVRNSSPKEQK"
     gene            12334..13059
                     /locus_tag="IVD26_000834"
     CDS             12334..13059
                     /locus_tag="IVD26_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAP6078833.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFKKKHKHVLEAIESIKRSVENS
                     ANVEDVLNFEQMFVEGNEPDSYGRNRRVYFMNRDGFSLLAMGFTGSKAINFKLKFIEA
                     FNEMEDVIRKNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNM
                     KVMEVLGGKESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLP
                     ETAIRMEIDQLNRQQRLFGDENE"
     gene            13236..13577
                     /locus_tag="IVD26_000835"
     CDS             13236..13577
                     /locus_tag="IVD26_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078834.1"
                     /translation="MEKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEQLACDQ
                     DDLGNFVSIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYERDNLIDISYYGQGKK
                     YIAEMEAELDE"
     gene            13570..14316
                     /locus_tag="IVD26_000836"
     CDS             13570..14316
                     /locus_tag="IVD26_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAP6078835.1"
                     /translation="MSEKEQPLKNRSDNTLFNSLYKINVKGVTEKRNDLTYLSWAWAW
                     AEVSKVCEAVDYEIYRDPETHRPYLFDEKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKKIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWLEDQYREETKEK"
     gene            14322..15008
                     /locus_tag="IVD26_000837"
     CDS             14322..15008
                     /locus_tag="IVD26_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078836.1"
                     /translation="MFKPLIDSYSAVLRRFKGNQIVARINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            15011..15841
                     /locus_tag="IVD26_000838"
     CDS             15011..15841
                     /locus_tag="IVD26_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP6078837.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLGSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDIDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            15858..16709
                     /locus_tag="IVD26_000839"
     CDS             15858..16709
                     /locus_tag="IVD26_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP6078838.1"
                     /translation="MESLASTMEKLIRRVLVQSGRCPECSEPLYSWRGKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            16706..17065
                     /locus_tag="IVD26_000840"
     CDS             16706..17065
                     /locus_tag="IVD26_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAP6078839.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            17080..17241
                     /locus_tag="IVD26_000841"
     CDS             17080..17241
                     /locus_tag="IVD26_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP6078840.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            17238..17543
                     /locus_tag="IVD26_000842"
     CDS             17238..17543
                     /locus_tag="IVD26_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078841.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKTR
                     RRMPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRAKNMDIDSKGRQFRYVEEK"
     gene            17543..17860
                     /locus_tag="IVD26_000843"
     CDS             17543..17860
                     /locus_tag="IVD26_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAP6078842.1"
                     /translation="MNLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     GSK"
     gene            17857..18243
                     /locus_tag="IVD26_000844"
     CDS             17857..18243
                     /locus_tag="IVD26_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078843.1"
                     /translation="MIPRFRSWYTPFKGKTIGQEMKYGQAGRLITHAEMAPDKYVLMQ
                     STGLKDKNGVEIFEGDVVLVNVSNGFDHLVNEKTVVQESEFHSGLVCKSLISGMEYRI
                     FSHQKMGYEYEVTGNIHENSELLEVE"
     gene            18240..18575
                     /locus_tag="IVD26_000845"
     CDS             18240..18575
                     /locus_tag="IVD26_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078844.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDIHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEQ"
     gene            18721..19290
                     /locus_tag="IVD26_000846"
     CDS             18721..19290
                     /locus_tag="IVD26_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAP6078845.1"
                     /translation="MNKQEAIKKLESIKVIGNDALAACYNESINAGITLMKKIDEPKK
                     LVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLYSVIIAGEYLVKEISCSNEVKLVSTAYLPQYLAH
                     HYQLTEKQIKAIDERYWPFAVPVEEVAEG"
     gene            19457..19762
                     /locus_tag="IVD26_000847"
     CDS             19457..19762
                     /locus_tag="IVD26_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078846.1"
                     /translation="MNVQVYLKRDLARFPRSWDTNSHPSEAEEEGYLMSANMIEITRD
                     DADEFDKKRSWYSVPNPMYTAVIEDYHISDRFILIDLERPKKRIKQYRRCGFSTKKW"
     gene            19786..19983
                     /locus_tag="IVD26_000848"
     CDS             19786..19983
                     /locus_tag="IVD26_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HAP6078847.1"
                     /translation="MNNRHRRVAKLRNQELNVAKVKFEREYGVSAEETYKVASQCVAD
                     ASDAIRKFGISILDIKWEDTE"
     gene            19980..20186
                     /locus_tag="IVD26_000849"
     CDS             19980..20186
                     /locus_tag="IVD26_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078848.1"
                     /translation="MKIYVVKFGNQFYRSDERSIGANTLSIVDILQSARWFDNLEEAN
                     QVSRRLGGLTQVYELVTVDHEGVE"
     gene            20186..20482
                     /locus_tag="IVD26_000850"
     CDS             20186..20482
                     /locus_tag="IVD26_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078849.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTREKPKFKVGDMVRCEA
                     EGFIYPFRGYVEKVLSNSAIIRIENTMECDKWLAKSKENLAVARLVDMEVIESK"
     gene            20558..20971
                     /locus_tag="IVD26_000851"
     CDS             20558..20971
                     /locus_tag="IVD26_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAP6078850.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            21848..22192
                     /locus_tag="IVD26_000852"
     CDS             21848..22192
                     /locus_tag="IVD26_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP6078851.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            22197..22478
                     /locus_tag="IVD26_000853"
     CDS             22197..22478
                     /locus_tag="IVD26_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078852.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            22581..22895
                     /locus_tag="IVD26_000854"
     CDS             22581..22895
                     /locus_tag="IVD26_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HAP6078853.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            22873..24567
                     /locus_tag="IVD26_000855"
     CDS             22873..24567
                     /locus_tag="IVD26_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAP6078854.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            24587..25765
                     /locus_tag="IVD26_000856"
     CDS             24587..25765
                     /locus_tag="IVD26_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP6078855.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            25728..26414
                     /locus_tag="IVD26_000857"
     CDS             25728..26414
                     /locus_tag="IVD26_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAP6078856.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            26414..27574
                     /locus_tag="IVD26_000858"
     CDS             26414..27574
                     /locus_tag="IVD26_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP6078857.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            27584..28459
                     /locus_tag="IVD26_000859"
     CDS             27584..28459
                     /locus_tag="IVD26_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078858.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIKIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            28456..28767
                     /locus_tag="IVD26_000860"
     CDS             28456..28767
                     /locus_tag="IVD26_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078859.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            28757..29110
                     /locus_tag="IVD26_000861"
     CDS             28757..29110
                     /locus_tag="IVD26_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAP6078860.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            29100..29501
                     /locus_tag="IVD26_000862"
     CDS             29100..29501
                     /locus_tag="IVD26_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078861.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            29494..29898
                     /locus_tag="IVD26_000863"
     CDS             29494..29898
                     /locus_tag="IVD26_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078862.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            29910..30515
                     /locus_tag="IVD26_000864"
     CDS             29910..30515
                     /locus_tag="IVD26_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP6078863.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            30535..30897
                     /locus_tag="IVD26_000865"
     CDS             30535..30897
                     /locus_tag="IVD26_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078864.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            30900..31082
                     /locus_tag="IVD26_000866"
     CDS             30900..31082
                     /locus_tag="IVD26_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078865.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            31099..34518
                     /locus_tag="IVD26_000867"
     CDS             31099..34518
                     /locus_tag="IVD26_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAP6078866.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITVIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWVSIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            34569..35306
                     /locus_tag="IVD26_000868"
     CDS             34569..35306
                     /locus_tag="IVD26_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP6078867.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            35316..37607
                     /locus_tag="IVD26_000869"
     CDS             35316..37607
                     /locus_tag="IVD26_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078868.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITASQAWQNAKTLAKPVIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            37631..39319
                     /locus_tag="IVD26_000870"
                     /pseudo
     CDS             37631..39319
                     /locus_tag="IVD26_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737855.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        13830 a         6117 c         8210 g        11408 t
ORIGIN      
        1 cttttttaca ttaccgtact catcatgaga aaaagctaat cattcgaaaa gaagaacttt
       61 cccttcaagt acaaaaagga ttactgaaaa tcaaggaaat accggaacgt ctcgaccgat
      121 tcatggacag caaaagtcag tatttgacat ttgaaccagg atttgctgat gttgtctggt
      181 cacaagatcc agaacgaaac atgcaggtct ataacgatat tgaggaaaaa gtcacttctc
      241 tttccgaaac cggtgtggag aacattgatc tagagaccct catttcaaaa gatgtggatg
      301 cttatttcca gacatatgtc aaagaattga ctaaaagttc gattcccaaa gatcttttgc
      361 cagatgaaat ctggcggtta accaatcaat tgtatgatgt ggctgaaaaa cggttagacc
      421 gtatttataa tgaaaaagct cgttttgctt ttgctttgca tctgcaaagt acattggatc
      481 gtgtgagaga aggtcatatg atcgtccacc cagatttgaa taacgtacgg aaaaatttta
      541 agagggaatt ccaggtagca atcgatcttt caacgatcat tgaagaagaa gaacaagttg
      601 agattccttt tgatgaaatc ggctttatta gtatgtttct ttctatcaat ctaggagaaa
      661 gtgagcctgt taaagaaaac aaagtagatg ttctcatatt gatgcacggc agacagactg
      721 cttcaagcat gttggagatg gcacaagaac tattaggaac aaaagtaggg aaagctttta
      781 atatgccact ggttatggaa gttcaaacaa tgtatgaaga agtgttacaa tatgtcaaaa
      841 actatcaaga gcatttgacg aatggcctac tcttgttaac agatatggga tcattaaaca
      901 ccttcagtga tttgatttat gaagagactg gcattcggac gaaagctatc acgatgacaa
      961 gtaccatgat tgtgatagaa gcgatacgga tggcaagtgt tggaagaagc ttagaagata
     1021 tttatcaaaa tatccagctt tcctttgaat cgatcgtacg tgatcagttc aaagcggaaa
     1081 agtctgaaac tttacagcgt aaaaaagccg taatcgtgac atgctttact ggtgaaggag
     1141 tagctgccaa attatatcag cgtattatgc cagtgattaa tcaaaataag gtagaactga
     1201 tccagatgca gtttttagaa cgtgaatcat tcaaaaaaca catcgatgcc ttattggaag
     1261 aatatgagat caaagcaatt gcgggaacag ttgatgttga ttatcaaaat atcccatttt
     1321 tttcagccta tgacgttttt gatgatgaaa aactaaatat tttaaagcgt atagctgatg
     1381 atgagatccc gacagctaaa attgtcgatt cacttgctgg atcattaagc gatgtctttt
     1441 ctattgatga actgatccgt tcattgcaaa agacagttca gcagatccag accgatttgt
     1501 cgattatcgt ggaacctgga gtagatactg gaatcgttat ccatttagcc ttcatgttag
     1561 acggattgat caaacaagaa agccatcggc aatttgagaa actgtctatt ttctcaaaaa
     1621 tttatcgttt ggaaatggat atcgttcggg caaacttgat ggcactagaa cgaaaatatc
     1681 aggtaaaaat tccagaagat gatatcgcat ttcttacaca aatgtttctt gaaaataaaa
     1741 taaaaaaatg aacacactaa tcatactgtt tacacactaa acatctgtgt gcgcactata
     1801 aaaaagagct aaaaagcatg aaaacgctat ttcagctctt ttttttattg gcatgcttct
     1861 tgcgttatat aaaagtgtaa aaaaataaaa ggagtgttaa aaatggcaaa aaaaacaatc
     1921 atgttagttt gttcagcagg gatgagtacg agtttattgg tcacaaaaat gcaaaaagca
     1981 gcagaagaaa aagggatgga agccgatatt tttgcggtct ctgcctcaga tgcagataat
     2041 aatttagaat ctaagaatgt cgatgtatta ttattaggtc ctcaagtacg tttcatgaaa
     2101 gctcaatttg aacaaaaact tgcgcctaaa ggtattccat tagatgtcat caatatgcaa
     2161 gactatggca tgatgaacgg agaaaaagtt cttgcacaag cagaaaatct aatgaaataa
     2221 atcaagtatg cagttggggg tataacaacg tggaagatca acaaaatcta gaagccatca
     2281 tggggttaat catgtttggc ggtaatgcaa agagcgatgc aatggaagcg attgcggctg
     2341 ctaaaatcgg tgattttgag ttagcggata ggaaaatcgc tgatgcagaa gaatcactta
     2401 tacaagcgca tcatgcacaa acagacatgt tgacacaaga agcacaagga aatcatatgc
     2461 aagtgacatt attgactgtt cacagtcaag atcacttaat gacatctatt gcgtttactg
     2521 atttagcaaa agaaatcatc gaactttatc gtcgcgtata cagcgaataa atacaacttc
     2581 ttttttgaac ggaagaagaa aaatttttga acggattttt tattttgtta taaggagaac
     2641 tctctttata taaaaaactt ataggaggaa gtaaaaaatg aacggactat caagttggat
     2701 ggagaaatac atcctgccgg ttgccgcaaa aatcggagcg caaaaacatt tagttgcttt
     2761 gcgtgatgct tttatcggca tactgcccgc aacaatggcg ggatcagtcg ctgtaatgat
     2821 caatgcaatt attcgtgatt taccgcaaca gtttaacagt acctatgctg acagtttagc
     2881 agcagacaaa ggaatctttg ccgtattgaa tgtcatcatc ggaatcaatg gttttgtctg
     2941 gaacggtaca ctagcaatcg ccggattgat ctttgccttt tcttgggggt ataatcttgc
     3001 ccgagcttat ggagtaaatg atctagctgg ggggatcgtt ggtttagcta ccttgattca
     3061 aggtatttcc tttggtccag cattatcagc agcattagat gtgaatgttc cttcaaatgt
     3121 cgcagatgca atcaatagtt ctgagattgg tgcaacgatt gcagatggca cactgtcagt
     3181 tggattatgg ggttggctaa aactagatca tttgaatgga aacgcttatt ttacagttat
     3241 gatcatggga gctatttcag tcattatttt ttgtaaattg atgcttgcca acattacgat
     3301 caaaatgcct gattcagtac caccagcagt atctaaagca tttgcagcca ttttaccagc
     3361 gacgatcgct ttatacgtca ttgctattat caattatatc gtaggtcgtg tagctgatgg
     3421 gcaactgatc attgatttgg tgcaaaaata tattgcagaa ccattcctag ggttatctca
     3481 agggttggga gcagtattga tcgtcacagt atttgttcaa gtattctggt tctttggtat
     3541 tcatggatca aatgtattgg caccagtgct agagggaatc tggggacaag cacaactaat
     3601 caatattgat attttccaaa aaggttataa cggaaaaact ggtacaccag ccgtgttaga
     3661 tgcaatcgaa gatggaaaag cttatatgtg ggtccgcgga tcgttcgatg cttttgcatg
     3721 gtttggcgga tcaggcggaa cgatcgtctt actgatagct atcttgattt tctctaaacg
     3781 tgcagattat ctaacagtag ctaaattatc cattgggcct ggtatcttca atatcaacga
     3841 accagtgatg tttggtctgc caatcgtatt gaatgcaatc atgtttatcc cattcttgat
     3901 tgctccagta gtagcaacag caattggatg gacagctact tatcttggcc tagtcgctcc
     3961 ggtatcgcag caagtcacat gggtagtacc gccgttctta ttgtcattct tagcaacagg
     4021 agcggattgg cgggcaccga tcgtaacatt agtatgtatg gtcgtgactt tcttgatttg
     4081 ggcaccattt gtcatctctg caaacaaaat ggaccctgcc gcaggcgaac aacaataaga
     4141 tgaacgtgag gagcgggacg ctttaagttt cgttcctcat aatgaatttt cgaggaggaa
     4201 ctgaaatgat tacaattgcc agtgcaatgc aacaagatga aatcaaagaa ttgttagaag
     4261 gatacaatga agaaggaatg acttttacat ttaaagaaaa acaaggaatc aagctgttct
     4321 ttgaaacaag tgcagaagat ccggaagttg cggctaaaaa agcaaaggaa ctaatcaaag
     4381 cacagccttg gggaacagtc ctttattttc aatcaacagc tgtttagaaa atggtttaaa
     4441 aagataggat ggttgagatg ataaaaaacg gtttattttt atgtagtatt ggttctttga
     4501 tcgtgttgta tagtttgaat ccacattcgc aaaggtatga tttgtatagt atggtcacag
     4561 gtctttttct aacaggatta ggaatctatt tcttcatgaa ggggaaaaaa agagaagaag
     4621 caaaggagaa aaataactaa tggaaatcac gaaaaaatta aatattccag catcgttttt
     4681 ttacgataaa gttatggact ctgtcctttt cgatgtacgt aaagcgaccg gcaaatcagt
     4741 aactagaaaa cagctgaaaa atttggagta cgtcaaacaa ttctcgcaaa ataaccgggc
     4801 tcgcataaaa atcgaagaag tcattgaaaa ccagtcttat aagtttcgta catcgacaac
     4861 gaagaatgaa ttcgtcgttc attatcaaat caaaccattg gacgattcga cctgtgaggt
     4921 tcattacaca gaaaaaatgg agtcttatgg catgcttcaa aagttgaatg atatgctttt
     4981 aggaacaatc ttgatgtatt ttaaacggag acgtttcaaa aaaatgctag atatgatcga
     5041 agcaacgtat taaatcaatg aaacatggta ctatttagtt attgaaaaat gaagtaagct
     5101 agaaggaatt tttcatagga agatagatct ttcctgcgaa tcctcactag cttttttgta
     5161 ggaaggggca gcaaaatgac aaacaaagta agagagctag gtgtatcttc gattgaggaa
     5221 atgtttgatt tagccactta tgcatttaat ggggcagata cacctgaaag gcgagaacgt
     5281 tttcgtacac ttgcggagaa ttcttggaat tacggatttt ttgatgagga ggatcggcta
     5341 acaagtcaag tcatggcgac cccttttcca gtgaattttt acggacaaga gtacctaatg
     5401 gccggcattg gctatgttgc ttcttatcca gaagcaaggg gacaaggcgg gatcaatcag
     5461 atcatggaaa agatccttga agattgccgt gatcgtaaag taagcttatc ttatctggcg
     5521 ccattctcct atcccttcta tcggcgctat ggctatgaac aatcatttga taaaatcagt
     5581 tatcaactaa acagtcgtga tgtgccgttt atcaaaaaaa aatctggaaa aataaagcgt
     5641 atggattttg aagatgcaaa agctgcaatc agaagaattt atgaacagat gccggaaaac
     5701 caacgagctg gtctgaagcg cgaagactgg tggtatacgt ataaattcaa gcaaaaaggc
     5761 aattaccagt ttgctttgca ttttgatgat aatgaggaag caacgggata tatcgtttat
     5821 cagcttgcaa cgtcttcctt tattattgcg gagtggggat ttttggatca tgatgctttt
     5881 tgcagccttg ttcgcttcgt aagttctcac aatggtgctt ttgaaacatt tgaatattca
     5941 tgcggctacg gcggtaatga tcaaaattat ctattagaaa atccatttgc ttctgtaatg
     6001 atcacacctt atatgatggc gaggatcgta gatatttctt tgtttttgga aaattatcca
     6061 tttaaaaaga gacaagctgc atttgcccta caaatagaag aagatcatta tgcgaaatgg
     6121 aatgaaggaa tcgtggaagt aacaatcgaa aatggaaaaa atcatctctc aaaagtagaa
     6181 caaacaaaac tcccaatcgt tcgaggaagt atccaacata tcacgcagct attattaggg
     6241 tatcgtaaag tggaagagtt ggtattccaa gaaagaatac aggtgacaaa agaatatgaa
     6301 gaaacgttaa gctcaatctt gccacagcaa cagccaattc ttaatgacta tttttgataa
     6361 aaaacgggtg atgacaatat ttttgtcacc acccttttgt ttttcatttg gcatttgaag
     6421 gaaaatgtta aagtaaatcc tcttttttcg taaatttgaa ttttttgttt tcttttgttt
     6481 tagggttttc ttttttgtgg tcttggattg cttctttcgt aatcttttcc cgattttttt
     6541 tagatgaatc taagcgttct gcgtatactt tttcttttgg cttatcattc attggaaagg
     6601 acctccctac attatttcat tctacctcta gtttatcatc tgttaaggac tagtggaaac
     6661 gttttgccta acttataagc tgattttttt agcagataag cttgcaagta aaaaacaaac
     6721 aagctacaat tgatttattg aaattgttcc tgtagctcag taggatagag caatcgcctc
     6781 ctaagcgata ggtcgctggt tcaattccag tcaggaacgt ataaataacc cctgtatcct
     6841 ttgcggtaca ggggtttgtt ttgtatttgt gccaaaaatg tgccaaacta gttatcattt
     6901 ttatataaac tatcgaacac agtattgatt ttttctttat cctgatcttc aagctctcga
     6961 acaatatgaa gataagtaga cattgtagtt tctaaactgc tatgtcctaa acgtttcgat
     7021 acgctaagta tatttactcc ttgataaagt aaaatagatg catgtgtatg ccttagtcca
     7081 tgcaaagtaa attgcttttc aatccctaat tcttttaatt ttttgcgcaa atatttgctg
     7141 acggcgtttg atgaaactaa tccatttttt aagttgaaaa aaacaaaatt atgagggttt
     7201 ttgatttcaa aattctcgaa taattctttt tgattgattt taaacttttt taagagatca
     7261 atcgtatgtt tatcaatgga aattttccta tttgaagttt cgttttttgt ttttccccat
     7321 tcatttaatt tataattcca tgttttatta atagtgatga tttgatcttc gaaatcgata
     7381 tcttcccatg ttaatcctag aagttcagca aatcgcattc cagtggcacc agcaactaac
     7441 acgagcatag gagaagagta ctgcgcagaa aggttttctt ctacgagttt cattaaagat
     7501 ttaaattgat cataatctaa atatttatct tcttttggct tcaatgaatc ttttcctttg
     7561 attactgctt ttctagttgg atcaaacgga attaatcctt cttctacggc atctttcaac
     7621 gacgctctaa tatggttatt aaacttaata acggtagatt ttacatggtc tttagcatac
     7681 ttatttaaaa agcgttgata tcccactcta tctaaatcag aaatcaatac cgctggcata
     7741 tatttcttta tgttcattaa cgtatcttcg tattttctat aagtgatagg agatactgtt
     7801 ccttctttat aaagttgcat ccaatcctca aagtaatctg ataataatag atttttgcga
     7861 tcccctttaa ggcctttgtt caagttatat tctaattcgt tggcggcatc ttttgcttcg
     7921 ccttttgtct taaatcctga ttttcttatc ttcgtgtatt ttccgtcatc ttttttgtat
     7981 gaaatttcgt attgccaact atttccacgt ttgactaatc ttgccataat tgaatctact
     8041 ctctttctct gatacaatag gcactataaa gaagcctact gtataggttt gtttttctta
     8101 gaacacgctt gctttggacg gtgggcgtgt tttttattta ttatacagtt gctttaaaaa
     8161 tagctgcttt ttcaaatgat actaaaggag agaagtggat ttctatttct cccttttggt
     8221 ttaacgtgaa atgagcagtt acatccattt gttttcctgg agcaacagat cccattgtat
     8281 tttcgttggc atatgtctct gattttttgt catctggtcc atatacttcc acatctgtac
     8341 ctacagggat atctgaatcg ccatcatttt ttacggtata agtaattttt actacttgtg
     8401 caggttggtt ttcttcaaat tgatttcttt catcagttag ttctacacta tttagtgtat
     8461 attcagcatc accaactttt acagtgtcac caatcttata gaaggtatcg cttttttctt
     8521 ctttagaaga tgaagcagag gttgaagatt tagttacttt ttcgccacca ttatcacttg
     8581 ctttattact atctgatcca ccatttaaag cagaaccaat aattataatt aaaattactg
     8641 ctaataccca aaaccatact tttttgtaaa aaggtttact aactttatac atttttccgt
     8701 cttgacccat aacttttttt gccatttaaa tattcctcac ttcttgttat aatatatttg
     8761 cgatctcaga aatgaggtat gagtccgtgt gccagcacgg gcttttttaa tgttttgctg
     8821 aaatcggttt ttttaataat tcttgatgta ttcatacata ttgccttgcg taagaatatt
     8881 ttttcttaaa atagcattgg cagacagcat aacaagtgta tctgagctta ttctgaatag
     8941 aataatactc cataaatttt tcgagattaa actgagattc atcagtcagt tcgttctcaa
     9001 tatagatatt taataaaatt agaatagcta ttttatctgc ttctgtttca aattttgagt
     9061 gaaaagttgt agaagtatcg tacaaaactg aatattcaaa atgagaagcg gtgaaatgcg
     9121 caagttcatg agataaatga aaggcttctg cagtttcgcc atatagattt tcattcaaaa
     9181 aaatgattct aggcttcgga taatagaagc caggctcttt catttccatg taaactactt
     9241 tcaaattgta ttcgctcaac atttctttca atttcaaata catacaaccc atcactccaa
     9301 ctattcattt tcctctaaag ctttagcaat tgcaatcgct ttacgcattg tctccttaga
     9361 tatttctttt ccatcaaaag aaaaaacagt atcgttttct gataaatcca catgtttagg
     9421 ggtttctttt tcttcgcgcc ccagaagata gtctacagag acatcgaaat agtcagcaat
     9481 ttcttgcaaa cgttctgtag aggggtttga gttcttaagt ctatataaga cgtttttacc
     9541 atagcctagg tcttcttcaa ctttatttaa tgattttccc tgttttttcg ctaactcttt
     9601 tattctctca aacgttatca tatcaatatt cctttcgttc aagaaaaaat atttaacttt
     9661 atttgttaaa attcgttgac tattttaaca aaaggtgtta atatcattct tgtaaacaag
     9721 tttaacaact aaaaagacaa caaaaaacac tatcgattaa taaatgccaa ccgccaagaa
     9781 agcttttaaa atcaatgttt atatgtctta tttaactatg ttctgatttt aacactgtat
     9841 gttaatttag tcaacgcagt ttttttaaaa gttgttaaat ttgtttacga atataaaaga
     9901 aaggagagaa gaatatggaa aaaaacagtc tcggcaaaaa tcgaagattt gaaattagac
     9961 atactgaaac aagcaaaagt ggcgatggaa cacgcggtag ataaagaaga ctctgccatg
    10021 gttgcagcca tagcagagat tttagctcac gtttagtcat cgtttttacg gtcttctgga
    10081 agctgaccat agataacagc ataatgaata tctaaataag cttgagcaat ttcttttggc
    10141 gaaattgatt cgcctttagt agatacttgt gattcgtgat ttagccatgc aacaactaaa
    10201 tccgcagcga tttcatcagt ttttttattc atacttattc accaccttat gcattatttc
    10261 agtagaccac ttactgataa gaaaattata tcaaagaaag gaatgaacaa aaatgaacac
    10321 accacaaatt tttagttttg aacaacatga agtaagaacg tttctagaaa atgacattcc
    10381 gtatttcgta gcaaacgatg ttgccaaaac tttgggatac aaaaatccca gtaaagccac
    10441 caatgatcat tgtaaaaaat caattgaaac atggggtaac gattcgttag gtcgtcgtca
    10501 aaaattcaaa gttattccag aatcagatgt ttaccgcttg attattaaat cgaacttacc
    10561 aagcgctgaa aaatttgagg cctgggtaat ggaagaagtc cttccaacaa tcagaaaaac
    10621 aggtagctat tcaaacgtac ctcaaagttt tgcacaagca ttgcgtttag cagcagattt
    10681 agaagaaaag aaccaattac tcgaacaaca aattgccgag tacgaaccaa agattagcta
    10741 cttagatacg attctttcat cgacagatac ggtagctact tctcaaattg cagctgatta
    10801 cggaatgtcg gcaattgctc taaacaaatt gctaaacgag ttaggtgttc aacataaagt
    10861 tagcggacaa tggatacttt accgaaaaca tatgaaccaa ggatacacaa aatcgcacac
    10921 aagtgagatt ccgaaagccg atggcggcac taaagttgta atgaatacca aatggacaca
    10981 gaaagggcga gtgtttattt acaacttatt aatcgcagag ggctattacc ctcaaatgga
    11041 tttagaggaa attggttaga aaggagtttt agtatgactg acattgcaga aatcactcaa
    11101 cgagatagag aaaaaatcaa agaatatgtc gaaagttcaa agttcttaac ttacaccatg
    11161 cttgctgaaa gattcggtat tagcaaaagc tacttatctt tgattttaaa cggtaaaaag
    11221 acttctgcag aagcaaatag aattatagat tcgattatca ctatgtacga attgtaaagg
    11281 gaggaacagc taatgcaata tctagaagcg aaaatcccag ttccagaagg ctatgtaatt
    11341 atctctcaag tggattatga ggagttaaaa aaagctgatg atactggtag atggatgacg
    11401 ttgccagaag tgctagaacg gattaacaga aaatatgatt ggtttacttc tagagtttta
    11461 aagaacccaa gatatagaaa tattatcgat atcgaaaaaa ataaaaatgg atttgtctat
    11521 tatccagttg aaggaagaga cacatatcta tttttaagaa gtaaaacact tgaattttta
    11581 gaaacaaatt tttcggaaat cttaaggagg taagcggatg ggaaaattta acagagcatt
    11641 agtattcagc gcaccactaa tcatctacgc tttaggactt tggggaagca gacaagcgtt
    11701 gataggaacg attgtttaca tggtctggat ttttatgggg cttgatgaag ctgagtacag
    11761 agcgaaaaag ccagtcggga gggactgact aaaatatgat ttttttattt ttgttccttt
    11821 gggctgctat tgcgtacttc atccagctcc ttgttgtcaa agttgctctt atttctttta
    11881 ggaagaacaa aagaaaatag cgctataaat gaaagataag tagccgctac attaaactgt
    11941 tcttttgaaa aagttacagt catcggaatg ataattgata ttgaggaagt aatcttaatt
    12001 aaaaatatag caatattttc aacatcgcgt tggtttttat ttaacattgt ccaacatgtt
    12061 ttagcaacaa taaaaataat tacacatgat attagcacac agactgaaaa aagttttaga
    12121 aatgcgatgt agtcaatgtt attgaattcc ttcaaaatac tatttttatt caatgtaata
    12181 aaaggaattt ttttaattga agacaggaaa gataaggtaa taaacagaat tatatatatg
    12241 gttaaagtcg cagtaagaat gtaattgagc tttttcctca tagaatcacc tcactttcta
    12301 acgaaaatta taccaaaaag gagagaagaa ataatgcaag aattagtaat tttgaaaaat
    12361 aaagaagctg taactacgag cttacaagtg gcagaaagtt tcaaaaagaa acataagcat
    12421 gtactagaag caattgaatc aataaaaaga tcggtcgaaa attcggccaa tgttgaagat
    12481 gtgctcaatt ttgagcagat gtttgtggaa ggtaatgaac cagattcata cggcagaaat
    12541 cgacgagttt atttcatgaa tagagacgga ttttccttgc tagctatggg attcactgga
    12601 agtaaagcaa taaatttcaa actaaaattt attgaagctt tcaacgaaat ggaagatgtt
    12661 attcggaaga atactgttcc tcaaacaatt gaagacatga tgatctatca attagaagaa
    12721 atgaaagatg ttaaaaaaga tgtttccatg cttaaagata ctatgcgaat tagcggacaa
    12781 caagagtttg aaattaagca aaaaggaaat atgaaagtta tggaagttct agggggaaaa
    12841 gaaagccgag cttatgaaga aatcagcaaa aaagtattct caaaattttg gtctgaattt
    12901 aaacgtacct tttcaatccc aagatatggc gagttacctc gtaagagatt cgatgatgct
    12961 gtttcattta ttgaaatgtg gttaccagaa actgcgatcc gcatggaaat cgatcaactg
    13021 aacagacaac aaagactttt cggtgatgaa aatgaataga gctgaagcgc taagaatagg
    13081 gacggtaatt gctaatcgct ggtggagaca caataaacca agcatcctaa gccaacaaca
    13141 tattgataag caaaaagctt ggcaacaaat aaaaaagtga ctccgccggc aagcatagag
    13201 tcacaaagaa aatacatcta aggagatgtt accacatgga aaaagaactt tccactctag
    13261 atcaatattt gactgatcct agttggggca aatcgaatat caaggaaaca agcaatcgaa
    13321 aaatcagacg taatcttttg acggatgaac aactagcatg tgatcaagac gatttgggca
    13381 attttgtgag tatttgggat catgtctatc ttatccatct atcaaaacat tcaaacaaac
    13441 ctgaatacat ctatgtcatc gaagatggct tgattgatgc gctcgaagag tacgaaaggg
    13501 ataacttgat tgatatctct tattacggac aaggcaaaaa atacattgct gaaatggagg
    13561 cagaacttga tgagtgaaaa ggaacaacct ttgaaaaata gaagtgataa tacgcttttt
    13621 aatagcttat acaaaataaa tgtgaaaggt gttactgaaa aacgaaatga cctcacttat
    13681 ctttcgtggg catgggcttg ggcagaagtt agcaaagtgt gtgaggcagt agattatgaa
    13741 atctatcgtg atccagaaac gcatcgtcca tacctctttg atgaaaaaac aggctatatg
    13801 gtttttacca gtatcacagt caacggagta aagcgtgaca tgtggttacc agtcatggat
    13861 ggtgcaaaca aggcaatgaa agatgagcca tatacctacg aagtcaatga ttatcagtgg
    13921 aataacgaaa cgaagaaaaa aaagattgtt ggaaaaatcg aaaagcgagt tgaagcagca
    13981 actatgtttg atatcaacaa aacgatcatg cgctgtcttg taaaaaatct agcaatgttt
    14041 gggctagggc tatatatatt tgctggcgaa gatatgccag aagatgtctc gatgcttgaa
    14101 ccagctactc aaagaagcaa aaagctattc ttggatgctt tacaactggt tgctaacaag
    14161 tacgaaaaat caattgatga agcaattgtt gcattgactg atgcagcttc cataaccgct
    14221 gatgacagta aatggaccaa gagagacttg ggcattctaa aacgaggcgt taattggctt
    14281 gaagatcagt acagagaaga aacaaaagag aagtgatatg aatgtttaaa ccgttaatag
    14341 actcatactc ggcggtacta agaagattca aaggcaacca gatagtggca agaatcaatg
    14401 aagaagtgaa tatcgagcga ttgaagacga tgtatgacgg ctacgatggc gatcgagtca
    14461 ttgaaattcg ctttattgat ccacgtcggt tcacagtaca gcaaagaaac ttcatctatg
    14521 cgctcatagg cgatattttc atcgatacag gcatgccaac ggacttctgg aaggaattct
    14581 tctacttccg ttttgaaggt gtcacagggc gcaaaataag cctcaaagat gaatcgaata
    14641 caactgtgag tgatgctaat gtcttagcaa atatcatttt agatttcatc tttgaacatc
    14701 atattccttt caaagaagga tatgagattt taccagcgaa tcaagagtat tacttctaca
    14761 aatgcattac aaaaagagtc tgctgcatct gtggcaaaac aggagctgat atcgatcact
    14821 ttgacaaagc gctgggaaga cgaaagcgca aggaagttga tcattcagag tacacatttg
    14881 cagcactctg cagaatccat cacacagaga aacacaaaat aggtgtgatc aatttcaaaa
    14941 ataaatatca aatcaaagga atcaagttaa accaggaaac aattaaaaag ttaaggatag
    15001 gaggataaat ttggctgaga taagttggat caaacttaaa actactatgt ttgacgatga
    15061 aaaaatacga ttaatccaag ctgttcctga gtcggatgcc atcatcgtta tatggattcg
    15121 attactagtt ttagcaggaa agactaacga cgatggtctg atatatatcc agaggaacat
    15181 gccttatacc gaagaaatgc ttgctacatt gttcggcaaa aacgtaaata cggttcgcct
    15241 agcgctaact acattggcaa atttcaacat gattgatcta ggcagtgatg gactgattgc
    15301 catcagtaat tgggaaaaac atcaaaatat cgaagggatg gataaagtaa ggctaaaaaa
    15361 cgctgaaaga aaccgtaaat acagagaaag aaagagacag gaacgtctca aattggaaaa
    15421 tgacgttagc gtgacgtcac gtgacggtac agataaagat atagaagaag atatagatat
    15481 agataaagaa gaaaagaaag gtaagtattc tgacgaacac ttacgccttg ctaaaaagtt
    15541 gcaaagtaat ttaactgaag attttccaaa agaaatgaat aaagtagata tcgaaaaatg
    15601 ggcagacaca atcaggttga tggaagaaag agataaagca tctatagaag cgattgagta
    15661 tgtgatcaat tggctaccta caaatgaatt ttggtttgga aatattagaa gtgctaagaa
    15721 actgcgagaa aaatttgaga agcttaaatt cgaaatcaag gcagataaaa ataatcataa
    15781 aaagcaaagt caaaaattac agtacagcaa tcctagtgaa tatgacgact tgccaattta
    15841 aaaaggagat gcatcacatg gaaagcctag caagtactat ggaaaagcta ataagaagag
    15901 ttttagtaca aagtggaaga tgcccagagt gcagcgaacc tttgtatagt tggcgaggga
    15961 aaaataagga cgggtcagaa cgttgtaaac caacatgcat gagttgtggt tataaagcgt
    16021 tacgtgtgaa agaggatata cagaccgaac ggatatataa cgacagctta aaagcacgag
    16081 cgttgagttt ttttcaaaat ggttcggtat taacagataa aactttgttt aaatgcaaaa
    16141 tggaaaatta tcacgtagtg gatcaagaaa caaaaatcgc tttagaaaaa gcaaaaagct
    16201 atacgaatga ggttctgctg aaccatcctg cacatttcat tctatcaggg aaatcaggaa
    16261 gcgggaaaag ccacttatca atggctacag cttgggaaat acttgagcgc tcaaattatg
    16321 acaagaaaat actttttata agctatcaag aattattaga gcaaataaag ttttcttata
    16381 acaatgctga actgagaaaa gaaattgaag gatcgcttat agccgatatt aaaacaactg
    16441 atttggtggt ttttgacgat attggagctg aattaggtag tggggtatca aatagtaggc
    16501 agtttacaaa caacacgtta aacacgctct tagaagcaag acagaacaag gcaacgatca
    16561 tcacaacaaa cttatctggt cctgaactaa gagaagccta cggtgaaaga attgtttcta
    16621 ggatatttaa gaattcagaa ggttatgcgc tgaaattcca gcaaacagca gacaagcgca
    16681 taaaaccagt gaaaggtagt atcgcatgaa taaataccgt aataaaaaaa ctgttcatcg
    16741 aggtatcaag tttgattcta tcgcagaagc agagtattac gatctagcct tgtggcaagc
    16801 tgaagcgaat ggctggaaag taaaacttca ggaaagattt gagctgatgc cgaaatttga
    16861 actagacgga aagaagtatc gcaagatcga gtatattccc gacttcacat tttataaaaa
    16921 cggcaaactt gtcaaagtcg tagatgttaa aggaatgcag acaaaagact ttaagatcaa
    16981 ggcaaagctg ttttgtcatc aatatcaagt gccgttgata ttagctaaaa aatatcggaa
    17041 tacgttcaag gaagagcgtt tttaaagagg tggtctatca tgacaacaga agaagtgatt
    17101 caaatgcgaa ttcgaagcat tcaacgtgag attgacgatc tggaacgaac aaaggcagtg
    17161 atggtcaatg aaacggcgag aaaggcaatc gatttgcaca tagagaactt aagaagggaa
    17221 attcgtagat tggaggaatg agcgtggata agaaagcagc aatgaaacga atcatcgaac
    17281 tgacacattc tgagaattgg caagaagaca aagaaatagt tgcagaagtc caaaagctcg
    17341 gtaaatcaat gtggactgaa aaaaccagac ggagaatgcc gagaaaaatt gcaatctggc
    17401 acggtgaccg aattctagta acaggtaccg ctgaacagtt atctgaaatt actggtctga
    17461 gcaaaaacat catctgggat agagcgaaga atatggatat tgattctaaa ggaagacagt
    17521 ttaggtatgt ggaggagaaa taatgaatct cattacacaa tacagtgata tcatcctcaa
    17581 gaaaatcatg atgaagattc agaaagacaa aaaatcaaaa gaacgagcgg aattagttaa
    17641 gttggaaatg gctgaaacag gggcaggagt gcgaagtagc aggcattgga aggcagcagc
    17701 aaacattgaa ttttattaca acgaaattca aaaagggttc gatcaaatgc gtgagctgga
    17761 tcggcaaaca aattggagca agaaacttca tcaagatcgt ttcaaatttg tagagaaata
    17821 taaagagata ttagacgaat acatggaggg cagcaaatga taccgagatt tcgatcgtgg
    17881 tacacaccat ttaaaggtaa aacaattgga caagaaatga aatatgggca agcaggaagg
    17941 ttgatcactc atgctgaaat ggctccagat aaatatgtgc ttatgcaatc cacaggactg
    18001 aaagataaga atggcgtaga aatatttgaa ggggatgtag ttctggttaa tgtaagtaat
    18061 ggttttgatc atttagttaa tgaaaaaacg gttgtacaag aatccgagtt tcattccgga
    18121 ttagtttgta aatcattaat tagtggaatg gaatatagaa tattcagcca ccaaaagatg
    18181 ggatacgaat atgaagtcac cggaaatata cacgagaata gcgagttatt ggaggtagag
    18241 tgattatctt agctactgac tacatcgatt ctttaaaaga tgaaaatggg aatgtcccag
    18301 cattgctaaa ttgtggaatt aaaagtaaga atagaatcat tttgttacgg atatcggctg
    18361 atttagcaaa atatctttat ctgagcaaga cagcagtata ttacactgcg gctacacgtt
    18421 atcagtacaa gggaaaaaca atcagtcagg attattatga tcgtttaatc agtcctgaca
    18481 tacatggaaa atcaaaatca gcgatcaagt tatttggcgc aatagagata tatgccgatg
    18541 attttccaaa tttatggttg aaggaggaac agtaatgaaa gactggttag aagaagcaag
    18601 cgccttagtt ggctgtttca taaactgtgc gtttatatct gtaattattg cactggtggg
    18661 atttgtatca ttgaaagtga ttatattgct ttggcagtta attttttagg aggaacagcg
    18721 atgaataaac aggaagcaat caaaaagtta gaaagtatta aagtgatagg aaatgatgca
    18781 ctagctgctt gctataacga gagtataaat gcaggtatta cgttaatgaa aaaaatagac
    18841 gaaccgaaga agctagttat tccacaactc gtggccggtt ggcttgagaa atctacggac
    18901 ccttttacga aagctgaaaa aatagcgtat ttaatcaaat ctaaagatgg tgattcatat
    18961 tatttctgtg attggtttgt acgagatggc atagtgacgc aagaacaagg agaagaatta
    19021 ctcgcttggg caacgagaca atcatatgaa acactattga gcttgtacaa cggctacgag
    19081 gtcgagaaag agccgttgta cagtgtaata attgctggcg agtaccttgt caaggagatc
    19141 agttgcagta atgaagttaa actagtatca acagcttacc tgccacaata ccttgcacac
    19201 cactaccaac tgaccgaaaa acagatcaaa gcaattgatg aaagatactg gccatttgct
    19261 gtgccagtgg aagaggtggc ggaaggatga gtagacagat aatgctccat ataccagacg
    19321 gaacaaaggc aatgacgatt accattgttg ctgcacaaaa agacggtggg ttggcgttga
    19381 aaacaaaaag cattgatacc aaacagattt tagaaggcag agatgtcgag atagagatcg
    19441 atgaggagga agcggaatga atgttcaagt ttatttaaaa agagatttgg ccaggtttcc
    19501 tcgaagctgg gatacaaatt cccacccatc cgaggcagaa gaagagggct atctaatgtc
    19561 tgctaacatg atagaaatta caagagatga tgcggatgag tttgataaaa aaagatcatg
    19621 gtactcggtt ccgaatccaa tgtatacggc tgtaatagaa gattatcata tatccgacag
    19681 atttattctg attgatctag aaaggcctaa gaaacgaatt aaacagtata gacgttgtgg
    19741 attttcaaca aagaaatggt gataacaaaa cagaggtgaa gaaaaatgaa caacagacac
    19801 cgcagagtag caaaactaag aaatcaagaa ctgaatgtag cgaaagtaaa gttcgaacgg
    19861 gagtatggtg tttctgcaga agaaacatat aaagtggcaa gtcagtgtgt tgctgatgca
    19921 agtgatgcta ttcgtaagtt tggaatttcg atactagata ttaaatggga ggatacagaa
    19981 tgaagattta tgtagtaaag tttggaaatc aattttacag aagcgatgaa cgttctatag
    20041 gggctaacac attatccatt gtagacatac tccaaagcgc aagatggttt gataatctcg
    20101 aagaagctaa ccaagtttca cgacgacttg gtggattaac gcaagtatat gaactggtca
    20161 ctgtcgatca tgagggggta gagtaatgaa actaaaagac ggattttacg ctagtagtca
    20221 tggtatcggc ggtttgatgc tagatatgcc gacaaagaac cctaaaacac gtgagaaacc
    20281 aaaattcaaa gtcggtgaca tggttcgctg tgaagcagaa ggatttatct atccatttcg
    20341 tggatatgta gaaaaggtat tgtcgaactc agcaatcatt cgtattgaaa acacgatgga
    20401 atgtgacaag tggttagcga aaagcaaaga gaatttagct gtagcgagat tagttgacat
    20461 ggaagtaatc gagagcaaat aaaaaagccg gatcgctccg actaacataa taaaacagac
    20521 aagtttatta tatcacataa aggagcggtt tgacttgatg caattgttac gagaggtaga
    20581 tttcaaacag acaagatgta atgcgagaga tgtgctgaag aactttcggc gtttggagcg
    20641 gatggcaggt cgctctttga tagatattaa gtctccaatt attacggata tgccgaaggc
    20701 gccgaagcac ggcaataagg cagaggacgc gatcattcag atgatggata tagaagcaga
    20761 gagagatgcg attttagcgg ctttgatggc tcttagtctg attagccgtc agatactcta
    20821 ctacagcttt tgtgtgccag atagcttctc aaactacaga attagccgtg aagtgggtta
    20881 ttcagaaaga agtatacaac ggatgaagtc ggaagctcta atagagtttg cagaagcata
    20941 taaacacgga agaataattg cttataaata atttggcggt tttttggcgg aatgatggcg
    21001 gtttttagct atttaccagt gatattatgg tagtgtcgaa agattagtga taggtctgag
    21061 acaaaataat aataaaagga acatcgtttt attattgttt cacaattaag cttcgataga
    21121 cagcaacgga aatattaaga ataaggatgt gaatttcaac tccttctaaa ttgttcttat
    21181 tatctatcat ccgttgctgt ctattgtttt tttaattatt cacacgataa ctaaaggtga
    21241 gtgaagagaa atgattccat taataatttc aatttttgcg ctctgtctta atgtctatat
    21301 gattggattt aaaaatgggc aaaataaaaa atagtagcag ccaagaataa ttttatagtg
    21361 tcactgtggc ggaaagggta gacgcttaaa aataaggtca atacgtcgag ggatagcctt
    21421 aacgttttat gatttgacca tgcaatgttc gattcattgc cagtgacttt ggcaaccgag
    21481 ggttggaaat gggcgctcaa agtacacgag caaggcgagg tcgatagtaa tcgatggaat
    21541 cggtgtaggt tgcttgatag agctataact gcatctcgtt tatgaggtgt agtttttaca
    21601 gattagatca ctctttgagt ggtcttttta ttttacacaa aggaggtaac aagaatgtat
    21661 agaccacaat acttagaaca gaagtatgaa gtaatcactg tgcaaaacgg taacggtgag
    21721 atagtacgaa agtatagaag accaataaag agcgatacat acaaacgaaa ggaaagcaat
    21781 gaagttattc cattgtatgg caaaagaata gctaagcatt aaataagatt gcgaaaggag
    21841 acggaatatg accgaggaat tctatagatg gctattacag ttgataagag aagatcgttt
    21901 ggttaagttc tatcagtctc ctaaatggcg caggcttaga gagaaagcga tgaaacgaga
    21961 tcactatgaa tgccaagagt gtagaagact aggtaagtat catagagtag agaacgttca
    22021 tcatataaag gaagtcaagg atagacctga cttagcttta gatttagata atcttatttg
    22081 tttatgtgtt gaacatcata atgaagttca tggcagatat cttacagcgt tagataaaca
    22141 agagaagaag atagaaagct tcgctaactt cgatgcaagt gaaaggtggt aagtgcatga
    22201 tcatcaatga caatggcaga gagtatgata cagaaaagat tgaagagtat tcatcttata
    22261 ctcagggatt aattaaacgt ttgatatacg ttcgctatgt aggtattagg gatctgttat
    22321 cagataactg ttgtagtaaa tacaaagtga atcaagtaag agaagcgttg aataaagata
    22381 ataacgtcga aagaataaaa aatgtttttg gatatagtat tgaagagatt aattattaca
    22441 ttgacttcgc tgaagctttc attccgatgg tgagataacc cccccttaaa ataaatcgca
    22501 aattttttgg gggtgatgaa acggaggggg ctgtcaggaa aagagatttt ttcgaacttt
    22561 atcatgaaag gagggctaaa atgtttaaaa acgaattgtc tcaaaatcgc tacagagaaa
    22621 aattacgccg ctctttaata agccaattgg aaagtcagaa aacaaatatt gagccattct
    22681 tagataatgt tgatcgttat atcagtttat gggaaacggc gatatcactg gaagaagata
    22741 tatccgagaa cggcattaga ctggagaatg gtaaaaagaa tgaatcagta gcgttgcttg
    22801 tttctgtcaa caaacaaatg ggattgatgt tggataaact tgccattact cctgaattgg
    22861 taggtgaagc aaatgaatca attcctgagt tataagcata ttgaaaattg gttcaaagct
    22921 atagaagaag gcactatcaa ggtatgcaaa gagcaattat tgctaaaaaa ttatctagaa
    22981 gaaagagtct ttactagaga agatatttac ttcgataagc agatggtaga ggattcaatc
    23041 aatataccag cacaatactt tccattcgaa ttaattccgt gggaaaaatt tctacaatgt
    23101 tttatttatg gtgttcgatg gaaaaaagat aaaacactag tgttcaatag atatctttca
    23161 ttaatgggac gtggtaatgg taaaactggt tttgcttctt ggaacaactt ctttctacta
    23221 accgctaaac acggtattaa aaattatgat attgatatct atgccaataa tgaaagccaa
    23281 gcaaagacta gttttgatga tgtatttaaa gtaattaaag atcatcctga tttagataaa
    23341 aaagtattta aagctacgaa ggaagttatt caaaatatcg ctacaaacag caaacttcgt
    23401 tataacacgg caaatgctag aacaaaagat gggaagcgac caggtgcaaa ccgctttgat
    23461 gaaattcacg aaaatgaaga ttattcaatg ataaatgtgg ctacttctgg tggtggtaaa
    23521 attcgagatt atagagaatt ttatgataca actaatggtc atgttcgtgg tggtccgctt
    23581 gatgacatta tagaagaatc aaaaatgatt ctttctggag aacttggaat tgacaaggat
    23641 ggagcagaat tttctagttt gtttccattt atttgtcgct tggataacga taatgaagtt
    23701 gatgatcccg acatgtggga aaaagcttgt ccaactatta attacaatgc agatttaaaa
    23761 cggaaaatgt ttcaagaata ctctcaaatg caacgtaatg ctggtttaag acttacgttc
    23821 atgaccaaac gaatgaacag acctatggaa gatacacgat ttgctgttgc ttcatatgat
    23881 gatgttctgc atacgaaaga aaaagaattt cctgaaaaaa tggatgaagt gataggaaca
    23941 gtcgattttg ctgatagacg agattttgcc agcgttgggt tgctaggaaa atacgataaa
    24001 gatgtttatt ttacacaaca tacttttatc cacgaatcag cccttcgatt acaaaacatc
    24061 aaacgagagg ttatagatat ttctatagat caaggaaaat cacagatcgt tcatggaaaa
    24121 aatatagaag ctgattatat tgtaggttgg tttcttgaaa tgagtaataa atattatatt
    24181 aaaaaaatcg ctatggatat gtaccgtgca aaaatattga agcccgcttt agaagaagca
    24241 ggttttactg tggaaattgt tcgaagcgga tctgttacac atggtatgtt aaaagatctg
    24301 gttgatgacc tttttattaa tcaacgttta ttttttggtg acgatgcgat tatgcgttgg
    24361 tattgcatga atgtatatga agagcatatt tctaatggaa atatacgcta tgaaaaaata
    24421 gaacctgaaa ctagaaaaac ggatggcttt ttttcattcc ttcatggttt gaatttttta
    24481 gatgatattt atgattctgc tcctgtaaca gtcacaaata gctcagtaga aaatacagga
    24541 actggattta ctcctctagt attctaactt gaaaggaggt gagaaagtgg ggatttttca
    24601 aaaggcggta ggatacttca caaaaaaagc aacggttcct ttagaagaat acttttgtaa
    24661 attgcaagtt gattttgtgt atcgaaaatt tgcgattgaa acttgtattg atttgattgc
    24721 aaatgcgatg agtaaagcgg aattcaagtc atatgaagat ggaaaaaata aaaagaatga
    24781 tctttactat aggctgaatg tagctcctaa taagaaaaat aatgcaacag aatttagaaa
    24841 aaaactgatc aggagattaa tattctacaa tgaagtattg atcgtttctc cgtctaataa
    24901 ttctagcgaa atatttattg cggatagttg ggatgtcaca gaatatgcat tgaaagatga
    24961 tgtgttttct caagtgcaaa ttaacaacat agtccttgat agagaatttc tagaaagtga
    25021 tgttatctat ataaaatacg cagatcaaca aattaggcaa ctagtcgatg cgtattatca
    25081 agcgtatggg aaactcattt ctagtgccat gaatgtttac aagcgctcta acgctcgtag
    25141 atacgtactg aaagggaatt tattccgacc gcaagacaat acaacacaag atcaaatcaa
    25201 taaaatgatg acatcacaat ttaaggcttt tatggaagct gataatgcag gtgcggtatt
    25261 tcaattacaa aatgagtaca cattagaaga tttcagcgga aacttccaaa gcaattcaag
    25321 agatataaaa aacttaatag acgacatctt tgagatgaca gcagcagcgt ttcacgttcc
    25381 gaaaaaccta ctaaagggag acatgagtgg gttatcggat caagtggacg cttttttaat
    25441 gttcgaaatc ataccgattg ctgaacttat tcaggatgcg tttaacgcta gtctctatga
    25501 agtagaagaa tacttgtcag ggaattttgt acgtgtggat acaactatga tcaagattac
    25561 tagcttcaaa gatttggttg acgctattga tgtaggcatt agaaatggag tatttacaat
    25621 caacgaagga agagagcgcg ttggaaatga tcgctctgat aaggcgatgg cagatgaaat
    25681 atttataact aaaaacaatc aacaagtatc gaaaggaggt gaggcgaatg acgacaatga
    25741 aaacatttct agcagtaaag aatgaaggcg cagtaccgca aatttttatt cagggattta
    25801 ttggttctag ttggttcttt gaagggaata ctgacaaggg aatcaaaaat attttggata
    25861 gtctaggtga tcaagaagaa attgaagtag taattaattc aaacggtgga gacgtatttc
    25921 aagggattgc tattgggaac ttacttaagt caaataaagc aaaagttaac gttgtgatta
    25981 acggcttagc cgctagtgct gcttcaatta tcgcaatggc tggcgatact ataaaaatct
    26041 acaacaatgc acaattgatg attcaccgcg cttccacata cggagaagga aatgtcgatg
    26101 acttccgtac gattgctgac caactggaat caattgataa atcggtaaag gcttcatata
    26161 aaacacgatt caatggcaca gatgaagcat tgcaagaact tcttgaaaaa gaatcgttta
    26221 tggatgcaga aacagctttg agttatggat tggtcgatga aattatcgat gcagaaaata
    26281 gctcaggtac tgaagctaaa aaagaacaaa gcgttgaaga aattttgaat gacgttaaag
    26341 aaaaaagagc agaaaaaatt gctgcattta cagcagcatt aaataaaaca tttggacaag
    26401 gagatgtaaa ataatgacag ttaaaaattt aaaaggtgta acagctgcaa gcgaccaatt
    26461 gatgaaagct tttaaagatg gtaacgaaga atcttttagc gcagctatgg taagcttatc
    26521 taaggaaatt caggataaaa ttttagaaga agcaacagca aaaaatcaag atcaattagt
    26581 attaatgaac cgtggtcagc gtgtattaac tacacaagaa acaaaattct ataacgaagt
    26641 agtgaaaaac gaaggttttg caggggtcga agaattagtg ccagctactg tatttgaacg
    26701 tgtatttgaa gatttagaac aatctcatcc actattgcaa aaaattactt ttgttaacac
    26761 aactggtgta acagaatgga ttgtgtcacg tggagtcaat ccagcatggt ggggtaaact
    26821 ttgcgaagct gttaaaaaag ttttagataa tggctttgat gtaattaaca tgaagcagtt
    26881 caagctatca ggttatattc ctgtatgtaa ggcaatgctt gatttaggtc cagtatggtt
    26941 agatcgttat gtccgtactg ttttagtaga atcattgaga attgcattag aacaagcaat
    27001 tgttgatggt actggtaaag atatgccagt cggaatgatg cgtgacatga gcaaacaaac
    27061 tagcggagaa tatgctgaaa aaaaagcaga acctattaca gctttagatg ctgtaactat
    27121 gggcggtttg atggcgcgac tatcaaaatt caatatcgaa ggtgtgaatg atccgattta
    27181 tcgtaatgtg aatccttctg atgtggtcct aattgtgaat ccaactgatt actggtctaa
    27241 agtattccca gctaagactg tactaactgc taatggagaa tacgtacaag tattgccagt
    27301 accagtttca gatttgcagt caacggctgt gccagaagga aaagcagtta ttggggtagc
    27361 ctcagattac ttcatgggtg taggatctac actaaaaatt gaagcttcag atgaatacca
    27421 ttttgttgaa gacgaacgca tttatctagc taaacaatat gcaaacggtc aacctaaacg
    27481 taacgatagt ttcattgtat tagatattag cgctttggga actactacta caactacaaa
    27541 accaacaacc acaacaacta caacacaagc gtaggtgatc agaatgaagt atattctttg
    27601 tcagccggca atcaatcggt ttaaatggga gcttgaagtt tgtttaacta atctgaagaa
    27661 actaggaatc aaagatatcg tattgctttt cagcagacac gatgatcaga ttcctatttt
    27721 ttttgagaag gaatatggtg ttgaagttca tgtgtacgat gatctgcggg acgacaaaga
    27781 gtatattcct tcgattaaac catatttatg gtggaaatat ttagaagaag atcattcgcg
    27841 tgaggacgac cgatatttct atatcgattc ggatgtcatt ttcaataaaa gaattaattt
    27901 gcgcaaattg ccttctaaag atgatgtttg gtattgtagc gactgctgta gttatctaag
    27961 tcttgattat attagaagct gtgaaaacgg agaaaatatt ctaaaagata tggcaaacat
    28021 tgtaaatgtt acagtagaat ctttggaaac tataaacact aattcaggag gcgcacagtg
    28081 ggttattaac cgccctaaag cgaattattg gaaaaaggtt tatctggatt ctaatcggct
    28141 atatcgctac cttagagggc aaaaaacaaa tataaaaatc tggacagccg agatgtgggc
    28201 acagctttgg aacatgatgt atttcaatat tggtcctaaa gttcacgagg aattagactt
    28261 ttgttttgct actgatccaa tagaaaaagt taaagaagta aaaatcttac acaatgctgg
    28321 agtaacaaca aacgatgaag atttattttt caaagggaga tacgtgactt ctacgccttt
    28381 tgatgaagat ttatcatttg taaacaagaa aaaatgctct tacgcatatg ttaaagcaat
    28441 taaggcggtg gttagatgac gcctgaacaa gtgactgaag aattgctaat agctgtgaag
    28501 gataatattt acgttacctg gaacgaagaa gatgagtcaa ttaaaaagat gatagctaaa
    28561 aatgctgttt atcttcaaag taaagtgagt acaacacttt ctttttctcc tgaaagctta
    28621 gaatacggat tgctaatcga aagatgtaga tacgactgga atcgtgcttt agatgagttt
    28681 gaacaaaatt tcgctagtga gttattaggt ttcattcaac attatgcgct acaagaatat
    28741 attgcaggtg atgtgaatgg cgaataatcg tagactcgaa gaaacattca acgatggttg
    28801 gttaaagatt ttgacgcaaa ctaccaaaag aaatgaacta ggaaaaaaga ttggtgtaga
    28861 agatacagaa atcacttctt taaaatttag aaatctttcc atgagagata gtgatataac
    28921 agctatggat gcgatgggat cgaaattaac taagaaagta aagactccat ttcatccaat
    28981 cgccaagaaa tttaataaag atcaatattt tatcgtaatc gatagtatgc gttacaacgt
    29041 tatctatgcc gattacgata atttttatat ctatttttat cttgaaagtg tgggtgaata
    29101 tggtgattga taattctaaa gaaaaagaac gtttaaataa gcaaatttct gctatcaaaa
    29161 cttccttaga agagcatttt ggcctcaaac tctttcaaga ctccgtaggc gaggatgagc
    29221 tacctgatga ttttaattac ttcattctcg aaacaggaga aatagaaatg atcactgagc
    29281 caaaatatag cgtgggtcaa aatctatatc taactttcta ttcagaaaat agagaagatt
    29341 taacaggaga ttcactagat attatttcat tgattcaaaa tcgttcgatt cgttttcaga
    29401 gaatggatcc caatcattta aaactagaga accaagatcg ctatatcgat caattggtat
    29461 ttacgtttag acgattattg aagagtgatt gtcatggcta aaaatagttg ggagctaaaa
    29521 ataaatggac atgatgaact tcttgtgcgg atggaacgct attcaagcga gagcgaacga
    29581 ctgattaacg aagcattgaa atcaaaaggt tcggctattg cagtggatag gattacagaa
    29641 aaaattcctg tttctgaagc agatttaaga agagggcacc aacacgcaaa aaatagtcgt
    29701 ccacttaaga ctcaatacat taatttgggt ttcatcatta gacctacaag aaaatttgag
    29761 tatttaaaat atcctgattt ggggataggt acttctaaaa gaaatcagcc ggacgaattt
    29821 atgagaagag gattaggtct tgcacttgat ccaattacag aacttctgat tcgtcaattc
    29881 gataaattaa ataaatagga ggaacaacaa tggctaaaac aacaacagta acaacttttg
    29941 acaatataag tattaaaaga atttctttta attttaagaa tgcaacaaat gcaatttcaa
    30001 ctgattgtaa tggacaatta gatggcgaaa cagaaatgca gagaattgta aaaaaatgcg
    30061 gttcaacaga agtaaaatcg aaatctaaac caatcaatat gacggtaaca attactgcac
    30121 atgtaccgat ggaagtttat cgacgcttca atgggttgaa acaagatgaa cgtattaaat
    30181 cgggaattta ctcttatggt cctgattccg taggggaaga tttctctctt gctgcagaga
    30241 tcgtggatga tttcgaagaa aaaaataagc tgattggtat gttagcatgc acttcgaata
    30301 caggattaac attctctatt gaaaatggtg cggatgaagt agctgcgtta gaactagaaa
    30361 caaaagttat gcaagatgaa tttggtaaat tttatcatga agcaattgtt gcagaacttg
    30421 aagaagactt aacagatcaa tggatgacga atctatctgc tgatgtgatt aaaaaaactt
    30481 cagttgtgac aactacggcc actcaatcac agtaaaaaaa acggaggtag cgaaatgaac
    30541 gaagattact caaaaattga actaaacgat ggaacaattt tgaatttaga acctaaactg
    30601 aatatcaaga aattattgat gatcaataga gattttaaca cagacgagtt tgcaaaaatg
    30661 actgtgggaa aaggatccat ggatatttct gttattcaag gtgcaaaggc tgtgtatatt
    30721 gcttaccgcc aagcgaacat gactgattat atttcattcg atgaatttat cgataaatgg
    30781 gattttgata tggctactgc cagctatatt tatcaattga tgatgttcaa acaagcacgc
    30841 gatgcttatc aaaaagaatt tgaaaaagca aataaggaaa aaaagcttca aaagtaaaaa
    30901 tgccaaagct cttagttgaa acgtgggtcg atgtctattc gatgttgacc gacgtttttt
    30961 ctatgccttc agatttggtt ttaagcgata tctgtttaga tgacattttg caaatggctt
    31021 acaacaagag tgcttatgaa ggatggaaaa actatgcaat aaaccaatcc cagaaaaact
    31081 aaagaaagga ggtaaaaaat ggctaaaaag agaacagaag cagaagtaac attcatagct
    31141 aacgatgacg gattgaaatc tacgttaaaa gaaatcagtg ctgaattaac taaaaataga
    31201 gcagaattaa aactagaaca agctcaatta caacagactg gttctgaatc agacaagtta
    31261 ggaagtaaat tatcttcttt agaaaagcag tatgaattac aaagtcaaaa agttgaagta
    31321 actagccaac gtttagccaa tgccaaaaaa tattatggag aaaattccac cgaagttcag
    31381 aaacttgaga gagaactgat taaccaacaa acagcgcaac aacgtttgtc aaacgaaatt
    31441 gataaaacga gtaatgcact agctcaagca aaaggcgaaa tacagacgta cgagtctaca
    31501 atgcaacagt tggatagtga acaaaaaaat gttcaagcta gtgcttctct gattgaatcc
    31561 gaatacaaaa aatggcaagc aactgctggt caatcagctt ctgaatccga gaaattagcg
    31621 aaagcccaag aatatgtttc tcaacaatct gaaaatgcag agaaaacgat agatatcctg
    31681 agacgacagt tagaagctac acagtctgag tttggcgcta catccacaga agcaatgcag
    31741 atggaggcga agcttaatga tgctgaacgt gaatttgaag agttaggaca agctgctaaa
    31801 aatgtagata caactaactt ggacgatatc ggaagcaaaa tagatatgaa taatctaatg
    31861 gaagcttctg acgttttaag cgacattggc gataagctta cagaattagg gaaacaagca
    31921 gtggactctg ctaatagtgt aggtagttcc cagagtaaaa tacaagctaa ttttggtttg
    31981 actaaacaag aggctgaaga attaacgaat gtagccagag acatttatta taaaggtttt
    32041 ggagaatcgt tagatcagtc cacagatgca ttgattttgg taaagcgtaa tttaggcgat
    32101 ttaaataatc aagatttaca aaatatcacg gaacaagcta tggtcctaga aaacaccatg
    32161 ggcgctgata tggatgaaac gttacgtggt gtaaatggct taatggtcaa tttcggcttg
    32221 agcgctcaag atgcaatgga tttaatggtt tcgggtactc aaaacggttt agataaaacg
    32281 cacgaattag gcgacaatat ggcagaatat agccaattat ggagtcaaat gggatattca
    32341 gctgatgaaa cgttcggaat gcttcaaaat ggtttagatg cgggtgctta taaccttgat
    32401 aaagtcaatg acttagttaa ggaaatggga atatcgttaa cagatggtcg atttgagcaa
    32461 aacatggata tgtttagtga aagtactaga aaagcttttg aagagtggaa aaatggcgga
    32521 ggaacacaaa aagacgttat taattccatg attcaagatt ttagcaatat ggatggtcaa
    32581 tacgaccaat taaataaagc ttctacaatt tggtctgcac ttggcgaaga taacgcgatg
    32641 aaagttgtcc aatctttgac tgatgttaac catacatttg atgatgttag tggatctgca
    32701 caaaaaatga atgaagattc tactactccg ttacaagaat taaacggaaa aatagctgaa
    32761 ttaaaggatt cattagctcc tataggcaac acaatcatag atgcactcga accagtaatt
    32821 gattttctag gaaagatggc tgatgcgttt aataatcttc cacaaccagt acaggattat
    32881 gccgtagcga ttggcggatt gactgctgca tttactttat taatgccaat aatagttggc
    32941 ttcatggctc taggtggtcc tactacatta ataataggag cagttattac tgttattgct
    33001 ggagttatag caattataaa aaactggggc gcaattactg actggtttaa gggaatatgg
    33061 agtaaattca ctgattggtt gggtggtact tgggaaagta taaaagaagg tgcctcatca
    33121 gtttgggatg gagttaaaga aacctggtct ggatttgtag attgggttca agatatttgg
    33181 caaggagttt ctgattggtt tggagagcta tggagcggat tagttgaagg agcttccaac
    33241 atctggcaag gagtccaaga gacttggcaa gcattcgttg attgggtttc aaatatttgg
    33301 aacggagtca aagaagtatg gtcgattatt tgggcagaca ttgtaggaat tgttcaaata
    33361 ccatggacct taataacgtc attgattcaa gccggtatta atattatcgt gggtattttt
    33421 gatgtagctg gacagttatt aggcgcagct tggcaagctg tttggacacc tatttctgat
    33481 ttccttaaaa acacttggga tactatgaca caatgggtaa gcatcgcttg gaatggaatt
    33541 gtaactacat tccatactat atttgatcca gtagtggcat ggtggaatgg tatatggaca
    33601 gctattagta ctacggcttc aaatatttgg aattcaatta gtgcaacagc ttctagtatt
    33661 tggaacagta tcaagaatac aatcactagc ttggtacaag cagctgctac agtaattcaa
    33721 aatatttggt caactgtatc tagttggtta ggtggaattt ggaattcaat cagctctaca
    33781 gcatcaaata tctggaatag cgtgactagt agtataagca atgctataaa cgcagctaaa
    33841 agtgccattc aaagtgtttg gaatagtata tcttcgtgga tcagcggaat ttggaacggt
    33901 atcaaaaaca ctgctttgaa tctttggaat ggaattacaa gcactattag ctctaaagta
    33961 aacgatggaa aaaatgcaat ttcaagcggt tggtccaatc taacaggtat tgtttccgac
    34021 atattcaata atgttaaaag tacaattgct aacatttggg aaggtatcaa aaagactgtt
    34081 agcgctccaa ttgattggat cagagataaa atcagtagta tctttgataa tttgaatatt
    34141 tctataccac atattccgtt accacatttt aaattgagcg gagaattcaa tccattgaag
    34201 gggaaaatcc caacgttggg tgttgattgg tatgcgaaag gtagtgtgtt taattctccg
    34261 aatattatcg gtgtcggcga agcaggacct gaagcagttt tacctttgaa aagatctgtg
    34321 ctgcaagaaa ttggtgatcg tatcttgagt agcacatcag tttcatctag ggcacaaacg
    34381 attcaacctg tgaataacta cgaattcaat ttcacaattg atggtaacgc agatgaggtt
    34441 actatgaagc aaacaactca acaaatcatt gatagcatta caaaagttca aaatgataat
    34501 gcttcggcat ggcgttaaac aggagagtat ttctcctgtt tttttagtat taaaaaggat
    34561 gtgaaaaaat gactgattgt atacattcta taatcgatgg atttcctgat tatttgcata
    34621 aattggcttt agctgaaaga ccaaccatac cttctccaaa aagacagaga gttgaaactt
    34681 ctgttttagg aaggttaggt ggcttagtac aagattactc gtttgaagac atgtcgttta
    34741 cattgcacta taactattta gaggatgtgg aagaccatca agcgttcaag caatcgtttt
    34801 atatcatgcg tcattggtta aattatgcaa agaaattaga attctctgat gatcccaacg
    34861 tctattatgt tatccagact atcgatattg gggatgcaga aaacgatatt gttgaatggg
    34921 gagagttcga tgtaaatatt actgcgaaac cattcgcaag agttcaagaa gatgtaccta
    34981 taaccgtaga taaaccacag tcatttaact tgctgaataa tagtttagaa gaaagttttc
    35041 caaagattat catcactcct tcagctactt catgccagtt catcttaaat gattatgtgt
    35101 ttagttttga aggcttagta gtaggaactg acgtagtcat tgatagtgat ttgatgcttt
    35161 gctacgaaga gcaatcggac ggagatattt tagatcggtc caacaaaatg aagaccatgc
    35221 aatatccgac attgcaagtg gatattaatt attttaattg tactggtttg agcaaaatac
    35281 aaatttatcg taatgggtta aggtaggtga aatagatgat cgataattta ataactattt
    35341 acgataaaaa cgacgcgaat aatttagctg aacatttata tgatacgcaa ggtttaggcg
    35401 ctttgtcaga ctggttaaca gctactgtta gcaataaatt aaacggagcc gagatatttc
    35461 agggtactta tccaataagc ggaactaatg cagatttgat tgtagaagga cgtattattc
    35521 agtgttatgt agatgaaaat cgagcaaaac agcgtctacg gatttattat gcaaagactt
    35581 ctgtaatagg caatacgata gaagtaaaag ctgaacctat tttcaatgat ataagaaaat
    35641 cggtgttgaa taaatatgac agtggaacag aaaagatcac tgctagtcag gcatggcaaa
    35701 acgcaaaaac tttagcgaaa ccagttattc cttcacagtt ttctttctcg tcattagtag
    35761 atacgcttgc taatgtgaag atagaaaagg cgaatttttt agaattcttt ggtggaaaag
    35821 agggatctat tctagatcga tttcatgggg aatttctaaa agataataac acattacgtc
    35881 atgaaaaaag gctaggcacg gatcataaaa tcaaagcgat ttatactaaa aacttaactg
    35941 gtcttgactt agagattgat gctcaaagtg ttttagttgg agtttatcca ttcattagca
    36001 gctcttcaga aggagaagac gagatcactc taccagaaga agttattttc acggattacg
    36061 tggatgatta tcctgctgga tatgtttctt ttgttgattt taaagacaaa gcgactgatg
    36121 tagccacatt aagggaagct gctaaagact ggttgaaaac aaacatagat aaacaaaaac
    36181 cacaagtgag tggttcgatt gaattagtac cattgaggca tcaaagaggc tatgaaaaat
    36241 ttgttgatct agaaaaagtt tcgatgggtg acggagtaga tgtgtatcat ccacagttaa
    36301 aagtgaatat gtcagcgaga attgtggaat atacgtttaa tgttctaacc aattcatacg
    36361 ataaattagt tgtaggaaac gtcaaaacaa acttcttaga aaacacagag aataatgtca
    36421 gcaatttgat taatgatgcc attgatcaat tgaaaaacgg tggcgaaatc agtgatttac
    36481 tcaatgatat tgtagatcat caaactgata tgattactgg tcaaaatggt ggttatgttt
    36541 tattagatcc taaagaagcg cctagtcgta ttttgattat ggacacacca gataagaata
    36601 ccgcaaggaa tgttttacaa atcaacaatg ctggtattgg tttttctaaa actggcatta
    36661 atggaacata tgaaacggca tggacgttag atggcggatt caatgcctcg tttattacgg
    36721 ctggtgaaat agtaggaatt actattagag gtactacatt aattagtgat ggtgctgatt
    36781 atagaacaag tattgctaat ggcaaaatga cttggtactc aaaaaaagtt aacaaagata
    36841 ttatggagct agaagcacgt gattatgtaa gtgctgatgc cggtattgta tcatacacca
    36901 tgaaaactgg tggtggtttc atgattagaa atccacaggg taacttggtt tttagtacgt
    36961 gggataatgg taataacaga ccgtttctat cttttggtgc gcccaatttc aggtatagca
    37021 atgctagtta tgtaacttct ggcgacggta gttctttaag cattaatggt agtgcgggta
    37081 actcatggga atttaaggta gctggtagga ctatgaaatt tactagtgat ggtatgctaa
    37141 cgttaccagg ttgttttttt ggttcatggg aagatgggaa acttgctagg tttgaacaat
    37201 caacggtaca agtatataaa gattttactg ttagaggtac taaaaactca actgtaccaa
    37261 cagaacatta tggacaacga ctattgaacg cttatgaaac tccagaatat tatttcgctg
    37321 attatgggga agccgttaca ggtgacgatg gtaaagttcg tgttgatatt gaccccatgt
    37381 ttgctgaaac agtaaatcta agtcggtata tgacacatgt gacacctaca gaactagttt
    37441 tgtgtgctgt tactcatgaa gatattgacc atttcatcat tgaaactagt aagccaaacg
    37501 tattagttag atggaattta gtggcacacc gtctagggta tgaagatatt agattaaaag
    37561 aggatacagc atatgatagc acagtgcttg accaaaaacg tttttaaaac gaagacaagg
    37621 aggtatataa atggctagca gtttatataa tttggcttta gatttcagca aagaattaaa
    37681 ctacaccaaa gctattatgg ctcgtcaagg tgataaaggg attacggtga cggttaaacc
    37741 gtttctaaat ggcttgcaga tggatacgag tggcggaaca tttactttaa aaggaacaac
    37801 accatctaac cgttacgtag ataatgttgc aactagtgta actagtgaag aagtcacgtt
    37861 ttctcttgat ggcacattta tgagtgaagc aggatattat aaacactgct acgtagaata
    37921 tagaaaagac aatcaaattt taacaacgca agatatcatt tttttctcac taggagtgtc
    37981 tgacatttcg caaggccaag ccgatgaata tgtttcgcaa ttagaagagt tgattcgaaa
    38041 gtacaacgaa acttttgatg cttttatggc tgaaatcaaa ggtagagtgg atagcttaaa
    38101 tcaacagatt actgatttaa ctggtcaagc taaaacgcta caagacaagt tagatgctct
    38161 gaaagaagaa atttctaagt taggtaactt acaagtgatg tacagtaaca gcatcgattt
    38221 cggggaatat gattatagtg ggaatccgaa tttaatgtcc aaactaaaat cgagcgattt
    38281 taacgttggt taccacgggt cactaacttc ggataacgaa aagctacatt ttacttctga
    38341 tggtacagga agcattatta tgtttacgcg tattaataca cctcagcttg ctagtgggaa
    38401 aacctatact ctgagtgcga aagttcgatt tgatgaagga actacaggag ctattgataa
    38461 attacgtttg gtgtatcgta catcaccagg agaaaagata ttattggaag caaatagtac
    38521 aaatattaca acagatgatg tagggaaaga aataacaatc aaaggtacag ctaacgttaa
    38581 ttatcaaatc acaaatttag atcgatttta tatgagtatt agctttgttg acagggataa
    38641 aataaatggc ggatttaagt tgtacgacat caaaatcgaa gaaggctcaa cagccacccc
    38701 atatcagcca aacttacttg atgaccctta ctggctaggt aaagcgcctt tgggtgagaa
    38761 tattgctaat aagtctgtta cgtttccaat caaatctagc gcctacagcc tataccaagc
    38821 taacatggaa gaagaatttg ttttaggtca aacctataca attaccatga aggcaaccaa
    38881 accacctatc caaacgttca ttgtttacaa cgaggatagt ggagattata gatatggtaa
    38941 cttagagcca gtagaagggt tagttgatac atggggtctg acttttacac cgcagaaggt
    39001 tggagttaac taccccaaac ggttaactat tatccagtat ccacaatcaa cagtaggcgc
    39061 atgccggatc gactggctca agattgaaaa aggcgacaca cgaaccccga atattagtga
    39121 gtataaatat cgtggtactg gtatgcgtga ttcaaacaat ccaaaagatt atgtttggga
    39181 tctagcacca gaatatgtcg aagataactt ggccacagat attaaaattt ctgaaattac
    39241 tggtaaagca aacaattata ccgatgggaa agtatcggag attaattcgc agttgactgc
    39301 ttcaattaat gaagtagaca ccacagctaa ggatgctcaa acaaaagcga atgctaatgc
    39361 gactgctata gatgaattag acaataagat cgatgaacgc attaatgata cagctactac
    39421 cacattaaca gttacaaacg ggaataccgg atcagcaaag ctttatcgtg aaggaaaaac
    39481 agtttctata tattttgtgg ctttaaacgg aaaaagcagt ggtggaaatg attcaacgat
    39541 actaacaatt ccagaaggct atcgg
//
LOCUS       DACBYO010000017        38494 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.017, whole genome shotgun sequence.
ACCESSION   DACBYO010000017 DACBYO010000000
VERSION     DACBYO010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.017"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..351
                     /locus_tag="IVD26_000871"
     CDS             <1..351
                     /locus_tag="IVD26_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6078869.1"
                     /translation="KPDPKKVGRKIRSIRKKLGLTMQEFGYEVSNSPRSTVSTWEHGG
                     NLPNKAKLKKIADIANCSVEDLLFDEGFISEKSQVKLINELKEENSKLKEKIKYYECL
                     FDGIESLLNSRKNS"
     gene            391..999
                     /locus_tag="IVD26_000872"
     CDS             391..999
                     /locus_tag="IVD26_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6078870.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLAFVREGDTLVFESLERLGRNSDEILDTVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVISIFSWTAQNEREEIKRKQKQGIAIAKKKGIYKGKPYEYSSTAKNPQ
                     KRFIYSEIVRMLGEGVPIKQIAEKTGTNRTLVYRIKNRILKE"
     gene            1005..1277
                     /locus_tag="IVD26_000873"
     CDS             1005..1277
                     /locus_tag="IVD26_000873"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078871.1"
                     /translation="MNEMLFILVANSFVLLIILTCDFILINIGVHSFIVNLLLFVFSL
                     IQVISFWILWKENLLNTIYVLIAIMPLLYLLAGIIGIARNRDNFFL"
     gene            1322..1660
                     /locus_tag="IVD26_000874"
     CDS             1322..1660
                     /locus_tag="IVD26_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078872.1"
                     /translation="MSIENAEITGTLLGYGEHDILTFSIGLKGNGWGVNYGSRALDGY
                     IKKEDERKPNQAAMSVIPEILKVVGVRKWEDLKGKYVRVETNGLGRTVTKMGNLIDDV
                     WLDLDDFFNT"
     gene            1826..2143
                     /locus_tag="IVD26_000875"
     CDS             1826..2143
                     /locus_tag="IVD26_000875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078873.1"
                     /translation="MWGVIYLVLYVIGKLTDLIYFNQAICFIIFILVIIIINACIFRS
                     GRNKKRRIDKTVLLNLIVIIIGVGTFTSKALISSVILLIFDFLIIYSVLYFINKAREY
                     LNQ"
     gene            2240..2812
                     /locus_tag="IVD26_000876"
     CDS             2240..2812
                     /locus_tag="IVD26_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078874.1"
                     /translation="MTAIFKARKNSNVSEYVKARLQKNNLEYILENGVGNLLNELTED
                     IDTDYIVLWDNGTLEVSIYGDFYQTHSKAMFKKSLSGRSDIKGIRKNSRFYKENQEVF
                     SKLAEIIPSMVAPISKRLSKKYFGTVYDGFGLKSNVEKYYYFDDTAYLAIKDMKRIPT
                     ETLDQLEQMKLSEFYSIYEEVVKVGATTNG"
     gene            2805..3644
                     /locus_tag="IVD26_000877"
     CDS             2805..3644
                     /locus_tag="IVD26_000877"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraA"
                     /protein_id="HAP6078875.1"
                     /translation="MDNQKVGNKKSKKNDLKKELINFRQSLKEREYNLIFRLDVWRAL
                     KVGSGFLGYMMWLYLARIGWINLYSIFRVFVEDESVKVGINTFGNLMFNLLLIALIVL
                     QSVKIPLTKELSGYTSILKPFQEGLKIICKQGTVVFLIGIFTDEINFIDYKNVIIRLC
                     SFLLVYLIATTFEKVTFRKIETLVQKEISKEEFCLETPYGKLQNVSLSTFCLNSKWEK
                     YLYRSERRVSWGSYSPILHECLRETGAVADGEIMVLKDVFGDYEIAFLDQPELRSDCS
                     ANG"
     gene            4150..4404
                     /locus_tag="IVD26_000878"
     CDS             4150..4404
                     /locus_tag="IVD26_000878"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078876.1"
                     /translation="MELTKGKRIAVVRFDSLSINDSRYIMPVTDVVFKTEDGIRLIWR
                     LPIKKSERLLKKIKVLEIEFVVTEKIAPETYLIEQVKIFG"
     gene            4839..6437
                     /locus_tag="IVD26_000879"
     CDS             4839..6437
                     /locus_tag="IVD26_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP6078877.1"
                     /translation="MLDRQAYMDVLEGILKDGLQKFNSKNVMPLNKSVNKKGAIVGFE
                     SKGRLIQSQGIIYRSLEKLYADSELLTHWTPNVFSWIGGGKGQSVWGHREDNLIQINT
                     FVADIDFLDKKDKISLNSLVLYLLEEGLLPYLILDTPKGYHAYFLIKNYNEESREYDK
                     ASYISNANGYKSLHVAKRISENIRKAIKNRLPEVDMGCNHFGVFRFPTPRNIVHFEPN
                     FTNTFEGYLEWSKEFERKEKEKKKGNMTVLSNKTRIKSNFRQIDTKWYDYLIHADIEE
                     GDRNSVIFTLSLACKQSGLSMEQCIDQMDQIEFKNDLSNKEVQRTIKSAYEGAYSGAK
                     GFYINELLEKYTTPSQFKKYAVATENKMVYKRKGNRVDPCYWVKFAKNREERTYSHFS
                     ESQDDLMAYLKSKEKQLNENQLYLELNMVNLSEETKIPLSTLKVIIKELKQDKDIIVK
                     TKRGRNGSTKIATRRFVEVKVLMAVISRNKGNKLFATELLEKDEQTLVEEIISRYENK
                     ALPFSVDKEKVQREKIAPIRGATG"
     gene            6694..7530
                     /locus_tag="IVD26_000880"
     CDS             6694..7530
                     /locus_tag="IVD26_000880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078878.1"
                     /translation="MFTSADEKVIEQKEPDRNGTINGIKRIVCNRCNGSGSFKYVSMG
                     RLTCGVCFKCNGLGYVDKKFKIMTPEYRAKRDKINLCNQQKAEEKRIAKELERLYWQI
                     KQKGFDQQIIYIVNEPDTYVIKDDLKSAGALYDDVIGWYFLNAVKHFSTEMVLTQDIY
                     EIKNSELIYKQTYLDKSIQTEGEFLFSVGDSFELVVTYSKYERIDNPFAYKAYIYFYE
                     FLDESGNLFIWKTSKNEIDVVQGEKICIKARLKDHKEWKKRNKVIRQNMIKNVRIIKD
                     YK"
     gene            7618..7980
                     /locus_tag="IVD26_000881"
     CDS             7618..7980
                     /locus_tag="IVD26_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HAP6078879.1"
                     /translation="MNSDGIFNNADFRKGDITVNRSDYVFPEESGVFVIEGVTVCRYW
                     GKRKNLILLLDSLDGRKLKFSFWSNTKYCCEPSRSREVDVEKESVRYLKDGSSIILTC
                     EKSKDAKITRIRNIEIKK"
     gene            8050..10164
                     /locus_tag="IVD26_000882"
     CDS             8050..10164
                     /locus_tag="IVD26_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HAP6078880.1"
                     /translation="MGTVILAEKPDQGKKFATALAGKTPVNKGGKYEFESEVFGHTIV
                     TWGIGHLVGLSLPEKYEWLPNKEKWDLANLPFLPKENELRYEVSKGKSQQYSTVKSCL
                     ENADMIIIATDPDREGENIAYNIFKLCKKKIFERPIKRLWINSLVKTEILKGFKNLRE
                     AEETVDLFKEANARQIADYLVGMNYTELFTLKLQEQGLRGVVSLGRVQTPVNTLVVEN
                     DQAIKNFKSEKYKVIECQTKNKEPKTIFRNSHEYFNMDELEVDTKKFGLDSASTGIIK
                     SIEVTQKQTEPQKLFSLGGIQEYANTKWKYSSKKTNKVIQDLYDQGYLSYPRTDSELI
                     TTNEFEYLKNNLHRYKELLKLNINTPCVQPNKRFVNNDKVLEHYALIPTMEIPDIAKF
                     KTEEKNIYEIIVKRTCLMFAEPYIYENTKVVLDVNGYEFMANGNVPVSLGWKQVDQNI
                     DEKKDGDGEGVSLPKFIEGEVVNIKVNFIEKNTKEPKRLTEGKLVGKTGIMAKLGLGT
                     PATRAGIIETLLAREYIRIENTKVYPTPKGYLLWDLTKNKDLLIGKPEITAQWEQALS
                     KIAKKQYTREEFLKNIYKYLDVTIQDLKKSDFESLYLEKSTIQNKYEINGYVVEEKAK
                     VFEVVKSETKEKFVIFKNISNKTITKTIVEELLKNGRTKKPLTGFKSKKNKKFSAILV
                     FDDLEFKVKMEFENKKADSNKF"
     gene            10292..10861
                     /locus_tag="IVD26_000883"
     CDS             10292..10861
                     /locus_tag="IVD26_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAP6078881.1"
                     /translation="MLYKNHLLVSNAIAIPFMGMTNTLTVSSIVALSLGALLPDIDEP
                     ESYVGKRTRGLSDLINIFFGHRGITHSLAFVLFIGLLIVPLTSKIGFVSLGVWLTVGV
                     FLHIFEDSFSNSGVNWLLPISEKTYHLNIYSTGSLIEFLIGLVALIWIVVCFKGQYFV
                     LSQDELVNVAVLKNMFIDIKDTLSKILLE"
     gene            10885..11484
                     /locus_tag="IVD26_000884"
     CDS             10885..11484
                     /locus_tag="IVD26_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078882.1"
                     /translation="MNNSPPKNPKDKAKLFTIENEYINKLKSIDSRVQNNYKGQRLYY
                     KSDLEVGEGINYYVPLSSAKESQKKITNKSVFKLYGDKAQEDFLGVLHINNLIPVPDQ
                     YAKIWSPLAKTDERYLTLVIKQARYIKAHEEEINKDCKLMVDSNMGTLDPVYFSKNRK
                     DIMTYKRITSDLTKLEQVSKAERNTSDSVRHRSNDIEIN"
     gene            11590..11904
                     /locus_tag="IVD26_000885"
     CDS             11590..11904
                     /locus_tag="IVD26_000885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078883.1"
                     /translation="MSFLEKYKAEVLDELEKEYKEVSVDYIQSDLLDDSLSEVEFVKQ
                     TLEKIILSEERPLLTLKQLFEKYHVLQNTYDTAKYVFHLSTENLDENIVEKAIDYLAI
                     EF"
     gene            11954..12178
                     /locus_tag="IVD26_000886"
     CDS             11954..12178
                     /locus_tag="IVD26_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078884.1"
                     /translation="MARPKKYKTEEERKKAREKSKKKWASRNKDKVAYIRAKSSAKLF
                     VEMSEDEDVEMLERWIEERKKRGKISDNND"
     gene            12427..12633
                     /locus_tag="IVD26_000887"
     CDS             12427..12633
                     /locus_tag="IVD26_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078885.1"
                     /translation="MIENRVLGFIECEDDINDTLEVLESIVFNTKVLDLKAVNNDMVT
                     HIIVDHEKAAQLGEILIGWANGEL"
     gene            12731..13576
                     /locus_tag="IVD26_000888"
     CDS             12731..13576
                     /locus_tag="IVD26_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6078886.1"
                     /translation="MKKLNLGYVMAINMFKGGVGKSTLTQLMADILSAMGFKVLVIDV
                     DPQGTVTKKFQRQYDLDVIGRMTLFDAVINMSFMESITSIKENLDIVIGSEQMSRFTK
                     VLRDMWRSTGFSDEGEEIFWNLFNYMINNDDLRSQYDFVLFDTIPTVSEFTDNVYVAS
                     DFLVIPTQTEQDSIDNLHSTVNNYRTAVKEVNSNLEILGIVPYLVDTRLKTGKELLTE
                     LQEEYGDMVYSNVVNDKGVVRRWGREGLDKSIPHSKKTYQMYVNIAVETLERLEKVTG
                     ENLLN"
     gene            13593..14030
                     /locus_tag="IVD26_000889"
     CDS             13593..14030
                     /locus_tag="IVD26_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078887.1"
                     /translation="MMGKTKKVTSAGGNNSGNPFGIKSGSGGFNIGQQMLKGKAGVKS
                     AGDKRKSVRVPIQLYNEVVARLSHGEKYPLMTEILTSFLKEFEQKGDSIIQNFNDLET
                     RPIKISEEAFRILKVFKFETDQSNTDIIASALTWYKEKNKGKA"
     gene            14054..14353
                     /locus_tag="IVD26_000890"
     CDS             14054..14353
                     /locus_tag="IVD26_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078888.1"
                     /translation="MNRDQYSHKEDKYVWENILILAGIVLGTILLAYFIVIPNLFTFI
                     NWFVPNFWSIFGYIIILWIAYKILSFIWFPVYSILGKWSYLILLATLIYIFMQIA"
     gene            14355..14801
                     /locus_tag="IVD26_000891"
     CDS             14355..14801
                     /locus_tag="IVD26_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP6078889.1"
                     /translation="MKVLNDIKANFGVITWYTIMLILCNITLSWIPSFFINQVNYNQG
                     ETSFSSSVLLISGIFAPFFEETFMRGIFQNWLEKNITIPLWGIYGIVAIVFSALHMQF
                     YFVPFFITSILLSYVYDRSEKKLVVPFLIHSLYNIFVIVISNIFSH"
     gene            14948..15277
                     /locus_tag="IVD26_000892"
     CDS             14948..15277
                     /locus_tag="IVD26_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078890.1"
                     /translation="MKIESAEPNLQTPRTSKIQNSKKKTKIFKSEDVVRVAWSVKTFD
                     EDRYVKVSMNGLFVQLGNFSSFKTIDELYPEIRNIVDSKGLIVAKRKSRNSGLAYCKD
                     KGIMIPA"
     gene            15651..19280
                     /locus_tag="IVD26_000893"
     CDS             15651..19280
                     /locus_tag="IVD26_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078891.1"
                     /translation="MKKIKLISVALFSLITLSTAHQSVASAEGANSEKAVVEESGDKK
                     VAIDDNVKNEAEKAAVVQGADGLMYVVVDEIDPKKLLEAESPLNNEQENTGSVEVGVD
                     KKRQEEADQANEKVKDFEDVDYNDISSLQSALNNPKFPFLSDDDLKEQLSKAKDTFES
                     EELIKKTRGYFSQRILELGNNLNDVPQRAKVNRRALVSTRASKVSETRINPPSGYPWV
                     IYLVRSNGYSYTENYAIRRTIDGKEAFCLQAGVTATNTYTGSASGYLSNSQKELISSF
                     LSAYKELGGWANNDSGKQRWIATQILVWENSNEKPKSITVTPNWKSGVTKSKSDITAR
                     ANTIRVKPTWDVNSKTVYEGEKATFTVKNTGGEHKLKVESVSGGGKATISGNKLTVDT
                     SGSTGTQIVVKMTKGSTELNPTTVWSNGSYQKLVTGSFYVNTSVTVNVKRKGTVEVLK
                     IDSETKKPLAGATFRFSYSGINKDVTTDSNGKAKLTERLKAGTVVKVKEIKAPNGYQL
                     DSSEFSITVKENQNVTTTRTNKRSTGSVEIEKLGDLDGLGLPNVVFTIYSSDNKVVKD
                     NLKTDSNGKIKVDELQFGKYYAVEKQGVTGYDPDGKKYNFEITQDTPSTKPAKVKVTN
                     IYQVSISEKVSDMNESQVLKNVWSADPNDYLQYDITTGNLKKSGERNVQSFIIEGFYD
                     NKNVDVLKSEVYVGSTNVTNSFDISNDTGNGKVTAKAKATVLTNNDFYNKSYNLRITM
                     KIKKSTIENTEKQKPLTIVKNSKVTVGSKISKSASSNDVETVLYSRKITINHIDEKDK
                     HLLKQDIDYKYDGETYEYKPRTDLFDKDGNNYKSDVIQKGKINGKDIVLTTPYHIPAL
                     SVNVDRIQIDTSRAVKNGFLPTELELSKKEEYGNELSKIVFKVKITDIDSNKVVYDNN
                     FKYKEFSSHIKLNLPTEYLTKNKKVNYSISILLVENPEKNKFDTETKDLKTIGYTSSE
                     KVLTNKDMTNNQVNYSAVVRTVKERANNNPVKEFRESINYKFTDTTKTKTGYGISVDL
                     EPTYKNEIGKQIDMKVYSYPMNELIDSKIDEIYQPIGEKEAEVKMDRLKNESKVESGT
                     NTQILSFQFPHMNVERKTGNVYADSQKNDESIKYELIDGGRKLYVPIWCDLGKYSIAI
                     KSSNFGGNYISLDMNQSIDVYAYMYATIDSETKKEDELLLEPVYPETTLPDNWSNKEI
                     DWLNK"
     gene            19341..19709
                     /locus_tag="IVD26_000894"
     CDS             19341..19709
                     /locus_tag="IVD26_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078892.1"
                     /translation="MRVQSTGYGNSVFDVKREFQDSRRKTRKLIAYFILSAIVFYIIR
                     FVLELNSMVFVDMVHKMLNGESVDFNFAYMLDQAKSNQVVAFLISVYYLIEKSVFSLK
                     EFLLGLFSRFVDVVGKGIEN"
     gene            19926..20345
                     /locus_tag="IVD26_000895"
                     /pseudo
     CDS             19926..20345
                     /locus_tag="IVD26_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311847.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            20358..21785
                     /gene="cpaF"
                     /locus_tag="IVD26_000896"
     CDS             20358..21785
                     /gene="cpaF"
                     /locus_tag="IVD26_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAP6078893.1"
                     /translation="MRVIEQEKPSQPTKSLVNLVKAKKFIKAENNISVKDEDFLQTLL
                     EDDTANYNPPIEEARLNMIRDDLTRNYSEEVLQALTDDEIRKKLVEVVLKEHGSLFNK
                     DKSREVAEYVVRECIGTGIIERIMTNDDITDVGWNGSQLSIETNSNKWLIDGEKLNIT
                     QEYIERVISKYAVVNDRDFNTGNPILDGMFKNVRISATHIDNSPDGATMSMRVARPKL
                     ALNTTNFENFAPDYILDLFEKMVKTKANICISGETGTGKTELQKLLLSFIDNHDRMIM
                     IEDVQETHAKELFPDKDIYAWITTPKKTISDLVKACLRNNPRWIIVSETRGAEAYEML
                     QAILSGHHVITTLHAINARAIPRRFVNMCASGYNINETAVEEDINRYFDFGVHIKKVV
                     INGKVIRYLNEIVEFSDTGTTTVFKQKLINGEFIRENGALSDDFKERMAEKFISFEFP
                     EDKIEKEDSETNELNSENSEVEVIT"
     gene            21782..22612
                     /locus_tag="IVD26_000897"
     CDS             21782..22612
                     /locus_tag="IVD26_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078894.1"
                     /translation="MKVQAVTKKKGIMDVSELNAYQVAYGKPLDYRDYLNYVGLPCIF
                     MGVFSFSLCYFWWVGLICGVIGAVYGYKVVMPKSVKRSYELKSLRERNKFINNMTQIL
                     TDESKTVTKALAMAKTRTKGELREDIQILESRLQGADKFQIAEAFREINEKYERDVVF
                     TQYFEQLETAIYEGRNNADTMKQIKSYHNDVKLKTESFLKIKDGYLQDLKQMLFIVAI
                     FIGAITFSFGFSTFFDGFARSPIGWGFGGVYFIIMVRFMKSFFMHYFDDEIMSLGVSN
                     "
     gene            22612..23400
                     /locus_tag="IVD26_000898"
     CDS             22612..23400
                     /locus_tag="IVD26_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078895.1"
                     /translation="MKVANVQKKASKKARIIKQENKSIWLKMLDENYYKKLREMNNSN
                     VSIIKWQKQRFLKSWIFVGVGLVMYLLLGKEWYYLAGGIATAIGFYIIQAKSINNIYN
                     QFRFERHLQFSKFTRLLIPYLKQKKDGGNLYGVFAKIVKRLDYDTDKQLLMKLMQDMT
                     DRPNDIQPFVEYAEQTSGTDMSVLFMQTIYDIRQGSADLDVIEELDRLASEELMAGID
                     SIIDFKSRRFVFYPTKIAMTSFILVVGFAVGVLFLNLKDINFGQ"
     gene            23419..23781
                     /locus_tag="IVD26_000899"
     CDS             23419..23781
                     /locus_tag="IVD26_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078896.1"
                     /translation="MQEQSIMEIVKWFIGLVIIMVMVSVGLFCYQLQDVNSFKQQVNY
                     QIERRGGLTAEALKSLKEYSDKNYQGRYKIESNLLNQKVEYGQAVDYTVKATIPIQIL
                     PLPDVTLSFEGNSVSQIR"
     gene            23952..24152
                     /locus_tag="IVD26_000900"
     CDS             23952..24152
                     /locus_tag="IVD26_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078897.1"
                     /translation="MDETVEQVNKPKRQRKKKVDPFIEMTDKIIQKKGLTPREFDQTA
                     IRKERQKLYDEFVKENIGLLLD"
     gene            24172..24450
                     /locus_tag="IVD26_000901"
     CDS             24172..24450
                     /locus_tag="IVD26_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HAP6078898.1"
                     /translation="MKEIMITKLAMNMPKMDFFDNVSKFMSNTTSKLQGISLSVIIFC
                     VVVTGMMFLFGEGPSRTAKKWLTYIVIGALIIFGASTIGQTIKSVGGF"
     gene            24532..26361
                     /locus_tag="IVD26_000902"
     CDS             24532..26361
                     /locus_tag="IVD26_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078899.1"
                     /translation="MKQRFEYSFEDVESKLLRKGKGLKKKNKYSLKQAEGLIAWVQHN
                     WPNKTEVTVMCKDTEDGAVYAFDGIEITPFGMGGEPIALFPIIEDQILQAPDNMINDP
                     NKLILDINSQYQSEPDIAEAKQESKSKKGLNLPSVLPNVKLPFGKKKHLEETPESDQF
                     FEEYETESTPELDEELELDEESEEVEAEIETDLEQAEETMLDETESFDFEEEIDMTTS
                     SHESVAINSQTSVPAYSQNTYHSEQNFALASSIPQTVRQIKKHETVQLTPLQEYCDLG
                     EEIESSIVSTTNKLQPENLFKFIGIPAVKNTRLDEYRINHAMQRLAEVKFENLREHYS
                     RQVNSMIAEALDKLREAIDVAWKKPYDLEVKKRYADILEEMETNSNSTLEEFVKRQYD
                     MVDEKIKKFETEQEIALQNFIANQEAEKAVFIANEKERAQNLIDTKSETITSELEKRR
                     EEFIDEEMYKMKIDMNQNLFDGKRLIKQELAVELANANEDVWENALKFITEIQNEINE
                     KTPLWASEIKETNILEQQAHQMQKEQQELKLKEESLAIKRLEAETNLKRLEELDHENK
                     MLKIKLETANSKNELYEYEKETQQKVVGSTQARNLSTLGLFRK"
     gene            26381..27097
                     /locus_tag="IVD26_000903"
     CDS             26381..27097
                     /locus_tag="IVD26_000903"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078900.1"
                     /translation="MSVFNNKNMVSGYVNHVAVYDGGSFKTMFVRLAVFNYMKEDKAQ
                     YEVINAQISCSVDQQGRLTTTSSHPKALLNKMLFDKLDKNLVEGMKVTLHGSLRGSDQ
                     VFLSGRWRNFKDLSSAEKEEYKSLPKGQLITRTNSFIYIEEVNMPSKEGFLKRKEELL
                     TENQMNEVKVTEPSQADQMETDDNDPVDNEGVVVETVEAEIIEPQEGTKISRRNTVSY
                     VRFEDMIYPEATMVEEDYPF"
     gene            27196..29970
                     /locus_tag="IVD26_000904"
     CDS             27196..29970
                     /locus_tag="IVD26_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP6078901.1"
                     /translation="MMWFKGKNKYHSGKIEGEDLPENVKDMVNLPLLLLGTVLGLFAN
                     LTVNYLINFFAAFLKALSVSEKGLMSIEFDHGFHMGYLKPFTSGTQYFMISIVVCIAI
                     TFLVYNKLDHESDRNLVYGQKGDSRFATVKEIQNEYHEIPEKKVRFEGMGGVPISHYK
                     DKYYIDRDTVNTVVLGASRSGKGETFVVPTIDNLSRAKEQSNMVVNDPKGELFSASKE
                     TLEKRGYRVLVLNIDDPLQSMSFNPLQLVIDSWANKDYHEASKRANTLTSMLFASGMG
                     TENEFFYKSAKNAVNAIILTIVEHCFDNNCIEKITMYNVAQMLNELGSLFYTDPKNPN
                     KEKNALDEYFNTLPQGNQAKIQYGSTSFAGDKAKGSILSTASQGIEMFTSDLFGKLTS
                     KMSIDLKEIGFPKSLQFKLNTEMVGKRVKISFLRKTDGKTKIINEYRVKVKALGLCVL
                     NFDESLRDGDFLEIRYETEKEKFRAWYSLEFPKRDSEDHDTTVITKKFKSGKRFLDLE
                     INSVVLKYTDQPTAVFMVIPDYDPSNHVIGSIFISQLYTELATNCKETPSKKCFRRVH
                     FLLDEFGNMPAIDNMDGIMTVCLGRNILFDLVIQSYSQLESRYDKGAKIIKENCQNHI
                     LIMSNDDETIEEISKKCGNKTIIGKSASSKRMDTDSSVTSSADQERIITFERASQLIE
                     GEQVILRNLHRQDKNRKKIRPFPIFNTKATNMPYRYQFLNDDFDTRKDINEIDIACDH
                     INLSLADNQIPFASFIRDLKTRMEYSITNEILISEDDYEEYRSLPNSQQTLDEEKLIG
                     LVKKSNFEKKSEVELSEDDFKLTTYLLDCQKHTKKLHDLMYEKDRFADDKSLDLVLKT
                     LNERYFSSELVQEFQKGRVTAQNIKQSKKQLAGIINVLGQVYIYAENNIFKTHIIAVK
                     NALTKLSKAI"
     gene            30043..32739
                     /locus_tag="IVD26_000905"
     CDS             30043..32739
                     /locus_tag="IVD26_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078902.1"
                     /translation="MVLLLATILLFVMVPTTAYAWPWDSDDKEALDFLLKYQDYLQFT
                     KGGFGSIVMQTFSWGIIRFAYWISKTIEGLIPQALSLFSFVESAGLNKVYQSVLNTVV
                     VGLMVLSLVIIGYKMVTGKGTLDLKSVGMNVVMSVALILLMPTMISSGITFAKTFYND
                     ATSINNQDGGVAWSLIEDGVTDLVYINKNDAYNRMGKEGQKKNALKEKDFFTYDFSEV
                     ITTDTAKELEADNPKAEYLKMKLTPDGDGNMQAVKIDDGWMAIFSDSFKGGYYRYTKN
                     TFALTLGLIALAIAYVFSAFIIITAILELAFKRVLGVLVFATDLETGQRSKQVLSDIL
                     QCYLTVGFQGFGLSMFAMFVNYLGTGSGSSVNPFIKAVAYVCAVIVLIKGSGTVMRYF
                     GVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRSKGGKNSGGNDQAEGEERKPERNFG
                     QSLSQKANKTGKTLGYARERGLSGLASDGATMASERATKPFKSMRDMANDTKNKFKEG
                     LDDGTVSAINKNSKPIVAKNKEDETGKYADSMPTRLSDRKDGAKVENADRIMSSSERM
                     REAMKNNAESNINPASAIQQKVKQDIEERKNAMHGQAKSAEELINQKRQEAKYTPEAM
                     NREEMLRKRVEGRTGANMDEKEALTKERIQEAKNSNTGLEKSVKENLQNSTSSQDRRS
                     VDVRENLQNTTSSQNGNRTVDVRENVQSSGTSQPRTVDVRENLQNTTSSQNGNRTVDV
                     RENVQSSGTSQPRTVDVRENLQNTTSSQNGNRTVDVRENVQSSGTSQPRTVDVRENLQ
                     NTTSSQNGNRTVDVRENVQSSASNQPRTVEVRETRAEASQGDKTQKINIIEERKERPN
                     EKVIVEQEVKEKKRPRFTYENNPLFQDISDKPNPLFDNLFKK"
     gene            32790..33098
                     /locus_tag="IVD26_000906"
     CDS             32790..33098
                     /locus_tag="IVD26_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078903.1"
                     /translation="MYRNPKNIKQEIKLFFFYLVDLGIVAGCVMCSVYFAKLMPVSPL
                     MKFAFYVLAFIVGVWMCVRTPNHPKERNILMVYYLLRMDRNRYHEVEFKRNKRGKIEV
                     "
     gene            33095..33712
                     /locus_tag="IVD26_000907"
     CDS             33095..33712
                     /locus_tag="IVD26_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078904.1"
                     /translation="MIIAEPNENKLAGLFDKLLDLVVPKDKDMCELLPYKKVLKDGIL
                     VTNDDKFQVLFKVKTTDLTSISEDGFMRMVNKLTYLNRVYLEPYKIYSLTYPTETIEQ
                     GIYWKNRIQEAKRELINNSDPYLEPYLKWNLKLAYDNYERVELVSTLPELMFVIAIYG
                     KTIKEVKNHADVMKQAGGRELDLQRINEEDLTNVITKLMNPNSSL"
     gene            33725..34180
                     /locus_tag="IVD26_000908"
     CDS             33725..34180
                     /locus_tag="IVD26_000908"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078905.1"
                     /translation="MLKKSRKGLKHCIKENGETRFYEWKEPNLIRVLGRFDTTSSDLL
                     ETCRNNKSLIVTKDTAKYRGIRCIEKESVGVHDIKMIEDILEIYPDYSLVVYDETVKP
                     VNQCEFYKALVKITKRFENVIFIWTSKISTNKQSEKTFFSDKNVFLRSI"
     gene            34194..35771
                     /locus_tag="IVD26_000909"
                     /pseudo
     CDS             34194..35771
                     /locus_tag="IVD26_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tra protein"
     gene            36507..38384
                     /gene="ltrA"
                     /locus_tag="IVD26_000910"
     CDS             36507..38384
                     /gene="ltrA"
                     /locus_tag="IVD26_000910"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP6078906.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIISYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
BASE COUNT        14424 a         4983 c         7864 g        11223 t
ORIGIN      
        1 aaaccagacc ctaaaaaggt agggagaaaa attcgttcta ttagaaaaaa attaggactt
       61 actatgcagg aatttgggta cgaggtttct aattctccta gaagcactgt gtcaacatgg
      121 gaacatggtg gtaacttacc gaacaaagcc aaactaaaaa aaattgcaga cattgcgaat
      181 tgtagtgtag aagatttgct ttttgatgaa ggctttattt ctgaaaaatc ccaagttaaa
      241 ttgataaatg aactcaaaga agaaaattca aagctaaaag aaaaaataaa atactatgaa
      301 tgtttatttg atggtataga gagtctgctg aactcacgaa aaaattccta gttaattaaa
      361 ctagagtaaa attatttgta ggtgttaaat atgttagttg gctatgcacg agtcagttca
      421 gatgatcaaa atttggaaag acagcttgaa gaatttagaa aaattggtgt cgaaaaagta
      481 tttgctgaaa aaaaatctgg tcgtaacaca gtagaacggc cagagttcaa taaaatgtta
      541 gcgtttgtta gagaaggaga tacacttgtt tttgagtctc ttgaacggtt aggaagaaat
      601 tctgatgaaa tactcgatac agtatctttt atagataaaa acggcatggg actaatggtc
      661 ttaaatttgc caatcttaga tacaaaattc ggtgatccta atttagaaaa acttgtcaga
      721 agcttagtga tcagtatttt ttcttggacg gctcaaaatg agagggaaga aattaagaga
      781 aagcaaaagc aaggaatagc aatcgcaaag aaaaaaggaa tctataaagg aaaaccttac
      841 gaatattctt ctacagcgaa gaatccgcaa aagcgattta tctatagtga aatagtgaga
      901 atgcttgggg aaggcgttcc aattaagcaa atcgcagaaa aaactggtac gaatagaaca
      961 ctagtttacc gtattaaaaa ccggatttta aaggagtgaa tggtttgaat gaaatgttgt
     1021 ttattttagt ggccaatagt tttgttttat taattatatt gacatgtgat tttatactta
     1081 taaatattgg agtacattcc tttattgtta atttattgtt gtttgtattt tctttaattc
     1141 aagtgattag cttttggatt ttgtggaagg aaaatctgtt aaatactata tatgtactga
     1201 ttgcgattat gcctttactt taccttttag ctggaattat tggtattgcc agaaatagag
     1261 ataatttttt cttatagagg ttagttagtg gaagaaatac acaactagga ggaagtaaac
     1321 gatgtcgatc gagaatgcag aaattacagg gacgcttcta gggtacggtg aacacgatat
     1381 attgaccttc agcattggtt taaaaggcaa tgggtgggga gttaattacg gaagtcgagc
     1441 tttagatgga tacattaaaa aagaggacga acgcaaacca aaccaagcag cgatgagtgt
     1501 cattccagaa attttgaagg tagtcggagt tagaaagtgg gaagacttaa aaggtaaata
     1561 tgtacgagtt gaaacgaatg gactaggtag aaccgtcact aagatgggga atttaattga
     1621 tgatgtttgg ctggatttag atgatttttt taatacttga ttccactatc caccaaaata
     1681 agcaactata tgggagttat cttttgcttt tttgaattag cagaaatttt tatgctgaga
     1741 ggacgattct aaggctactt cagttaaata aggaaggtaa ttaagctact gcataaatag
     1801 tggtttaatt taaaaggagt attgtatgtg gggggtaatt tatctagttc tatatgttat
     1861 aggaaaacta acagatttaa tttattttaa tcaagcaata tgttttataa tatttatttt
     1921 agtaataatt attataaatg cttgtatttt taggtcagga cgaaacaaaa aaagaagaat
     1981 agataaaaca gtcctattaa atttaatagt gattatcatt ggagttggaa cctttacaag
     2041 caaagcttta atttcaagtg ttatcctact aatatttgat tttttgatta tctatagtgt
     2101 gttatatttt attaataagg ctcgtgaata tttaaaccaa tagaaaacgg tctaataaaa
     2161 tattggaggt gtttaaaaaa gctacaagag ataggaggat ttaaattcat agagatgaag
     2221 gttcaaagga gagtaaaaaa tgacagctat ttttaaagca cgaaaaaatt ctaacgtatc
     2281 tgaatacgtt aaggctaggt tgcaaaaaaa taatttagag tatattctgg aaaacggtgt
     2341 tggaaatctt ctaaatgaac tgactgaaga tatagataca gattatattg ttttgtggga
     2401 taatggaaca cttgaagtat ctatttatgg agacttttat caaactcact caaaggcaat
     2461 gtttaaaaaa agtttgagtg gaagaagtga cataaaagga atcagaaaaa acagcaggtt
     2521 ttataaggaa aatcaagaag tgtttagtaa gcttgcggaa atcataccta gtatggtagc
     2581 gcccataagc aaacgactga gtaaaaaata cttcggaaca gtttatgatg gattcggctt
     2641 gaaaagcaac gtagaaaagt attattactt tgatgatact gcatatttag caatcaaaga
     2701 tatgaaacga atacctacag aaacacttga tcaattagag cagatgaaac tttctgaatt
     2761 ctattcaatc tatgaggaag tggtaaaagt gggtgctact accaatggat aatcaaaaag
     2821 tcggaaataa gaagagtaag aaaaatgatt taaaaaaaga gttgataaat tttagacaaa
     2881 gtctgaagga acgagaatat aacttaatat ttcgtcttga tgtttggagg gcgctaaaag
     2941 taggttctgg ctttttaggc tacatgatgt ggttgtattt agctagaatt ggatggataa
     3001 atttgtatag tattttccgt gtatttgtag aggatgaatc agtaaaagtt ggaatcaaca
     3061 cgtttggtaa tttgatgttc aatctattat tgatagcctt aattgtgcta cagtcagtta
     3121 aaattccttt gacaaaagaa ttatcagggt atacttcaat cttaaaaccc tttcaagagg
     3181 ggttaaaaat aatttgtaag caaggtactg tggtttttct tattggaata tttacagatg
     3241 aaattaactt tatcgactat aaaaacgtaa taataaggct gtgttcattt ttattggtgt
     3301 atttaatagc aacaactttt gaaaaagtaa ctttcaggaa aatcgaaact ctggtacaaa
     3361 aagaaatttc aaaagaagaa ttttgtctgg aaactcctta cggaaagctg caaaatgtat
     3421 cacttagtac attttgtttg aatagtaagt gggaaaaata tctatataga agcgaacgaa
     3481 gggtgtcatg gggcagttat agtccaattc tacatgaatg tctgagagaa actggtgcgg
     3541 tagccgatgg tgaaattatg gtgctgaagg atgtctttgg tgactatgaa attgcttttc
     3601 ttgatcaacc tgaattaagg agtgattgtt ctgcaaatgg ttaaattact atctaaactt
     3661 tcttatcgaa aaagattgtc aaatacgtcg gaaaatgaaa agacaagaat agtagattct
     3721 aggcctttta gagtatggat aaaaaaagag aaaagaaagc gctaggtgcg ttttcttttt
     3781 ttgctaaaga ctatttgtag tcaatgaaac aacaaaaaaa gcgactactt gtagtcactt
     3841 ccaagaaaag taagagccag tgaaagctac caacaatcaa ctggctcaca agacttatcg
     3901 tagcaaagag aatttttggc aagcatacga agtcttatag ttcaattctg atattttaat
     3961 tataagggat taacgtagat aatgcaaggg gaaatgactt attaatactt agaaacaaat
     4021 ataagttgac aatgattaat aaaaatttaa ggtaatccgc tatatgacta cttgtagtct
     4081 tatagttagt tttatccttg actacaagta gtcaaaagcg gtataataat agtgcaaagg
     4141 agggataatg tggagttaac caaagggaaa agaatagcag ttgttcgatt tgattctttg
     4201 tcgataaatg attcaagata tattatgcct gttacagatg ttgtgtttaa aacggaagat
     4261 gggataagat tgatatggcg tttgccgatc aaaaagagtg aacgattatt aaaaaaaatt
     4321 aaggtacttg agatagagtt tgttgtaacc gaaaagattg cgccagaaac ctatcttata
     4381 gagcaggtaa aaatatttgg gtgataaaaa caccaatgaa aaaaactctt gttaaatcgg
     4441 ctggaaatag cttataataa acttagtttt gaagccaaac aaaacactaa aaaattctag
     4501 taatcaattt tgcaggttga ttactaagta tctaactgca ataaaggaat attagcaaaa
     4561 aagcacatga atagagctac caactttatt catgggaact cgtagcaaag agaatttggc
     4621 aagcatacga agtctaagaa atgagctacc aactcatttc agtattgcgc taccgtcaca
     4681 acaatgaaag agaaagtaga tacattttta tctatttgta gttttctaaa cattgaattg
     4741 aaggcatagt gtatatttta ggactcacag ctacgagaac ctagaaatat attctatgtc
     4801 ttttttgcta tctaaaattg atagcaagga gaaaatcaat gttggatcga caagcataca
     4861 tggatgtctt agaaggcatt ttaaaagatg gattgcaaaa atttaatagc aaaaatgtta
     4921 tgcctttaaa taagtctgtt aacaaaaaag gagctattgt aggctttgaa tcaaaaggtc
     4981 gtttgattca aagccaaggt ataatctatc gatctcttga aaaactttac gctgatagcg
     5041 aattattgac acattggact cctaatgttt tctcatggat tggtggggga aaagggcaat
     5101 cagtttgggg gcatagagag gataatttaa ttcaaataaa tacatttgtt gctgatattg
     5161 atttccttga caagaaagac aaaatcagtt tgaacagcct tgttctttat ctactggaag
     5221 aaggtctttt accatatctt attttagata caccaaaagg gtatcatgct tattttctaa
     5281 ttaaaaacta taacgaagag tcaagagagt acgacaaggc aagttatatt tcaaatgcga
     5341 atggttataa atcgctccat gttgctaaaa gaatatctga aaatataaga aaagcaatta
     5401 aaaatagact tccagaagtt gatatggggt gcaatcattt tggcgtattt cggtttccta
     5461 cacctcgtaa tattgtgcat tttgaaccta atttcacaaa tacctttgag ggatatttag
     5521 agtggtcaaa agagtttgag agaaaagaaa aagaaaagaa aaaaggaaat atgactgtac
     5581 tctcaaataa aactaggatt aagtctaact ttcgccagat cgatacaaaa tggtacgact
     5641 accttattca tgcagatatt gaagaagggg atcggaatag tgttattttt acactttcat
     5701 tggcctgcaa acaaagcgga ttatcaatgg agcaatgtat tgatcaaatg gatcaaattg
     5761 agtttaaaaa tgatttgagt aataaagaag ttcaaagaac aataaagagt gcatatgagg
     5821 gagcgtattc gggagctaaa ggcttttata ttaacgaact tttggagaaa tatactacac
     5881 ctagtcaatt caaaaaatac gctgtcgcta cagagaataa gatggtttat aaaagaaaag
     5941 gcaatcgtgt tgatccatgc tattgggtta aatttgccaa aaatagagaa gaacgtacct
     6001 atagccattt tagtgaaagt caagatgatt tgatggctta tttgaaaagc aaagaaaagc
     6061 agttaaatga aaaccagctg tatttagagt tgaatatggt caatttatct gaagaaacta
     6121 agattccttt atctacgtta aaagtaataa taaaagagct gaaacaggat aaagatataa
     6181 ttgtgaaaac taagcgtggc cggaatggca gtacaaagat cgcaacgaga agatttgtcg
     6241 aagtcaaggt tttaatggct gtcataagcc gtaacaaggg aaataaactg tttgctacag
     6301 aattactaga gaaagatgaa caaacgcttg tagaagaaat tataagccga tatgagaata
     6361 aagcattacc ttttagtgta gataaagaaa aagttcagag agaaaaaatt gcaccaatta
     6421 gaggagctac aggttaaaac gcctttattt tttagagttt tttaaatagc taaattgcct
     6481 tgtttacata tctagctttc tttcctgtgc atggcagtct aagctagaat aaccaacata
     6541 gtgtcttagc tatatgttct ttgaaaatgg aatacaggag aatgggactg gtctttacta
     6601 gcgtagttta tgagtaaatg tggtgatata agcgttgact acaagtagtc aacgcggtat
     6661 aataatgtta attaatagct tgagggggat tctatgttta cttcagcaga cgagaaagtt
     6721 atcgaacaga aagagccgga tcgtaatgga actataaacg gaattaagag aattgtttgt
     6781 aatcgatgta atggttccgg aagttttaaa tatgtgtcta tggggagatt gacttgtgga
     6841 gtttgtttta aatgtaatgg tttgggatat gtagataaaa agtttaaaat tatgacacca
     6901 gagtatagag ctaaacggga caagataaat ttgtgtaatc aacaaaaagc ggaagaaaaa
     6961 agaattgcga aggaattaga aaggctttat tggcagatta agcagaaggg atttgatcag
     7021 caaattattt atatcgttaa tgagccggat acttatgtta ttaaggatga tttgaagtca
     7081 gctggtgcat tgtatgatga tgtcattgga tggtattttt taaatgccgt taaacacttt
     7141 tctactgaaa tggttctgac tcaagatatt tatgaaatca aaaattctga attaatttat
     7201 aaacagactt atttggataa atctatacaa acagaaggtg aatttctttt tagtgtaggt
     7261 gatagctttg aattggtagt aacatattca aagtatgaaa ggattgacaa tccctttgct
     7321 tacaaggctt acatttattt ttatgaattt ttagatgaat caggtaattt atttatatgg
     7381 aaaactagta agaatgaaat tgacgttgtt caaggtgaaa aaatttgtat aaaagcaagg
     7441 ctgaaagatc ataaagaatg gaagaaaagg aataaggtta tcagacaaaa tatgatcaag
     7501 aatgttagaa taattaaaga ctacaagtag taaagttgga ggaaaccttt ctttattagt
     7561 ggttattttt ttgatataat taatatacgt cagatagata ataaaagagg tggttgaatg
     7621 aactctgatg gtatttttaa taatgctgat tttagaaagg gggatataac agtaaatcgt
     7681 tcagactatg tatttcctga agaatcaggt gtatttgtaa ttgaaggtgt gactgtttgt
     7741 cgctactggg gaaaaagaaa aaatttaatc ttattgttgg attcgttgga tggaagaaaa
     7801 cttaaatttt cgttttggag taatacaaag tattgttgtg agccttcgcg ttcaagagaa
     7861 gtagatgttg aaaaagagag tgttaggtat ctaaaagatg ggtctagtat aattttaacg
     7921 tgtgaaaaaa gtaaagacgc aaaaattaca aggataagaa atatagaaat aaagaagtga
     7981 ctacaagtag acactgtggt tacttgtagg attgtttcta ataaatttat agatagaagg
     8041 ttaaactata tgggaacagt aattttggca gaaaaaccgg atcaggggaa aaaatttgca
     8101 actgcattag caggaaagac tccggtaaat aagggcggaa aatatgaatt tgaaagtgaa
     8161 gtgtttggac atacaattgt tacttggggg atagggcatt tagtcggttt atcattgcct
     8221 gaaaaatatg aatggttacc taataaagaa aaatgggatt tagccaatct tccttttctt
     8281 ccaaaagaga atgaactgag atacgaagtt tccaaaggaa aaagtcaaca atattctacg
     8341 gtaaaaagtt gtttagaaaa tgcagacatg attattattg cgactgaccc tgatcgagaa
     8401 ggcgagaaca ttgcatataa tatttttaaa ctatgcaaaa aaaagatttt tgaaagacca
     8461 ataaagagac tttggattaa ttcacttgtg aaaacagaaa ttttaaaagg attcaagaat
     8521 ctaagggaag cagaggaaac agttgatctt tttaaagaag caaatgctag gcagatagcg
     8581 gattatttag ttggtatgaa ctatacagag ttattcactt taaaattgca ggaacaagga
     8641 ttaagaggag tcgtatcact tgggcgtgtt caaacaccag ttaatacact agttgttgaa
     8701 aatgatcaag caataaaaaa ttttaaatca gaaaagtata aagtgattga gtgccaaaca
     8761 aagaataagg aaccaaaaac tatttttaga aatagtcatg aatatttcaa catggatgag
     8821 cttgaggtag acacaaaaaa attcggctta gattccgcca gtacaggaat tatcaaatca
     8881 atagaagtta cacaaaaaca aactgaacca caaaagctct ttagcttagg tggaattcaa
     8941 gaatatgcaa atacaaaatg gaaatactct tcaaaaaaga caaataaagt aatacaagat
     9001 ttatatgatc agggctatct ttcttatcca agaacagata gtgagttgat tactacgaat
     9061 gagtttgagt atctgaaaaa taacttgcac cgttacaagg aactattaaa gttaaatata
     9121 aatacgcctt gtgtacagcc gaataagcga tttgttaaca atgataaggt tttagaacac
     9181 tatgctttaa ttcctacaat ggaaattccg gacatagcaa agttcaaaac tgaagaaaaa
     9241 aatatttatg aaattattgt taaacgaact tgtttaatgt ttgcagaacc gtatatctac
     9301 gagaatacaa aagttgtcct agatgtaaat ggttatgaat ttatggcaaa tggaaatgta
     9361 cctgtttcac ttggatggaa acaagttgac cagaatattg acgaaaaaaa agatggtgat
     9421 ggcgaaggtg tgtcattacc aaagtttata gaaggtgaag ttgttaatat aaaagtgaat
     9481 tttattgaaa aaaacactaa ggagccgaaa cgactaactg aagggaaact agtaggtaag
     9541 acaggaatta tggccaagtt gggattgggt actcctgcaa cacgagcagg tattattgag
     9601 acacttttag cacgtgaata cattagaatc gaaaatacaa aggtttatcc tacgcctaaa
     9661 ggctatttat tgtgggattt gacaaaaaat aaggatttgt taattggtaa acctgaaatt
     9721 acagctcaat gggaacaggc attgagtaaa atagcaaaaa agcaatatac acgagaagaa
     9781 ttcttgaaaa atatttataa atacttagat gttactattc aagatttgaa aaaatccgat
     9841 tttgagagtc tgtatcttga aaaaagtacg atacaaaata agtatgaaat taacggatat
     9901 gttgttgaag agaaggcaaa agtatttgaa gtagttaagt ctgaaactaa agaaaaattt
     9961 gtgatattta agaatatttc aaataagact attacaaaaa caattgttga agagcttctc
    10021 aaaaacggaa ggactaaaaa gcctttgaca ggttttaaat cgaaaaaaaa taaaaaattc
    10081 agtgctatat tagtttttga tgatttagag ttcaaggtga aaatggaatt tgaaaacaaa
    10141 aaagctgatt ccaataaatt ttaaaagatt aagcaaaaga gctataacaa gttcttttgc
    10201 ttttgttgtc ttataaaata aagaaaaaaa ggaaatattg gttatgacaa atactaataa
    10261 agttagttat actagaaggg agttttagaa tttgctatat aaaaaccatt tgcttgtcag
    10321 taatgcgatt gctattcctt ttatggggat gacgaataca ttgacagtta gcagtattgt
    10381 cgctttaagt ttgggggctt tattgccgga tatagatgaa ccggaatcat atgttggtaa
    10441 acgtacacga ggactatctg atttaataaa tatatttttt ggccataggg gaattacaca
    10501 tagcttggct tttgtattat ttataggttt gctgattgtg ccacttacga gtaaaatagg
    10561 tttcgtttct ttaggtgtgt ggcttactgt aggagtattt ttgcatatat ttgaggatag
    10621 ttttagtaac agtggtgtaa attggttgtt accgattagt gaaaagactt atcacttgaa
    10681 tatatattct actggtagtt taattgaatt cctaataggc ttagtagctc taatttggat
    10741 agttgtttgt tttaagggtc agtattttgt attgagtcag gatgaattag taaatgtagc
    10801 tgtactaaaa aatatgttta ttgatataaa agatacgtta tcaaaaatct tattggaata
    10861 aggaaaggaa gaaagcaatt gaaaattaac aactcgccac cgaagaatcc aaaagataag
    10921 gcaaaattat ttactattga aaatgagtat attaataaat taaagtcaat tgacagtcgt
    10981 gttcaaaata actataaagg acaacgattg tattacaaat cagatttaga agtaggagag
    11041 ggaataaatt attatgttcc actttcttca gcaaaagaaa gtcaaaaaaa gatcaccaac
    11101 aaatcagtat ttaaactcta tggtgataag gcgcaagagg attttttagg agttttgcat
    11161 attaataatt tgataccagt tccagatcaa tacgctaaga tatggtctcc gttagcgaaa
    11221 acagatgaac gatatttaac attagttatt aagcaagcta ggtacattaa agctcatgaa
    11281 gaagaaatca ataaagattg taagttaatg gtagatagta atatgggtac tcttgatcct
    11341 gtgtatttta gtaaaaatcg caaagatatt atgacctata aacggataac gagtgatcta
    11401 acgaagttag agcaggtaag taaagctgaa agaaatacaa gtgattcagt acgtcataga
    11461 agtaatgaca tagagattaa ttaaaggtag gaaggcttag gcttttctgc ctttatttat
    11521 gttggttaag aatgaaatat atgatattat aattatatat cagatagaca taaatggagg
    11581 gtgctaaatt tgtcattctt agaaaaatat aaagccgaag tcctagatga attagagaaa
    11641 gaatataaag aagtgagtgt cgattatatt caaagtgatc tattagatga tagtttaagt
    11701 gaagtagaat tcgtaaagca aacattagag aaaattattt tatctgaaga aagaccgctc
    11761 ttaactttaa agcaattatt tgaaaagtat catgttttgc agaatactta cgatacagca
    11821 aaatatgtat ttcatttgtc tacagaaaac ttggacgaga atatagtaga aaaagctatt
    11881 gattatttag ctatcgagtt ttagagatgt ggtaaaatga acatactgat taaatattgg
    11941 aaggttgaat aaaatggcta gaccaaaaaa atataaaacc gaagaagaaa gaaaaaaagc
    12001 tagagagaaa tccaaaaaga aatgggctag tagaaataaa gataaagttg cttatataag
    12061 agccaaatct tcagcaaaat tgtttgttga aatgtcggaa gatgaagatg ttgaaatgct
    12121 agaacgatgg atcgaagaga gaaaaaaaag ggggaagata agtgataata atgattgact
    12181 acaagtagtc aaagagatat aataaggctg tagggaggta ttctccctta tttttaaaat
    12241 taattgacta cttgtagtca atgggaggag gggttgaaaa agagaactta tgttcgtata
    12301 atgatgaaag gagagtggta ataaaaaaat taactatcta gtttgtggta ttaatgttcg
    12361 tttctattaa tagaacagaa actatgaaga aaataggttt tgaagaatgt tgtggaggga
    12421 gttagcttga tagaaaatag ggttttaggc tttatcgaat gtgaagatga tattaatgat
    12481 actttagaag tgttagagag cattgtattt aatacgaaag tattagattt gaaagcggtc
    12541 aataacgata tggttacgca tattattgtt gatcacgaga aggctgccca attgggagag
    12601 attctaattg gatgggcgaa tggagagttg tgaaattctc aaattttcat aaatgactac
    12661 ttgtagactg ctttattgac tacaagtagt ctgtaagtta taatcaaatt atcaaagcga
    12721 ggtatagata atgaaaaaac ttaatctagg ctatgtaatg gcaattaata tgttcaaagg
    12781 gggagttggt aaatctactc ttactcaact gatggcagat attctttctg cgatggggtt
    12841 taaggtttta gttattgacg ttgatccaca aggaacggta actaaaaaat ttcagagaca
    12901 atatgattta gatgttattg gtagaatgac tttgtttgac gctgtaatta acatgtcctt
    12961 catggaaagt atcacaagta tcaaagaaaa cttagatata gtgattgggt ctgaacaaat
    13021 gtcacgcttt acaaaggttt taagagatat gtggagatca actggttttt cagacgaagg
    13081 tgaagaaatt ttctggaatt tgtttaacta tatgatcaat aatgatgatt tgagaagtca
    13141 atatgatttt gttttatttg atactattcc tacggtttct gaatttacag ataatgttta
    13201 tgtagctagt gatttcttgg taattcctac gcaaacagag caagattcaa ttgataattt
    13261 gcatagtacg gttaacaatt ataggactgc tgtaaaggaa gtaaattcta atttggaaat
    13321 tttaggtatt gttccttatt tagtcgatac aagacttaaa acagggaaag aattgttaac
    13381 tgagctgcaa gaagagtatg gtgatatggt atattctaat gttgttaacg ataaaggtgt
    13441 tgtaagacgt tggggacgag aaggattgga caaatcaatt cctcactcca aaaaaactta
    13501 tcaaatgtat gttaatattg ctgttgaaac attagaacgt cttgaaaaag taactggcga
    13561 aaatttatta aattgatagt aaaggtgttg caatcatggg aaaaacgaaa aaagttacga
    13621 gtgccggtgg taacaattct ggaaatccgt ttggcattaa aagtggttcg ggtggtttta
    13681 atatcggaca gcaaatgcta aaaggaaaag caggagttaa atcagctggt gacaaaagaa
    13741 aatcggttcg tgtgccgatt caactatata atgaagttgt agcaaggctt tctcatggcg
    13801 aaaaatatcc gcttatgaca gaaatattaa cttcattttt aaaagagttt gaacaaaaag
    13861 gagatagtat tattcagaat tttaatgatt tagaaacacg tccaataaaa atttctgaag
    13921 aggcatttcg tatattaaaa gtattcaaat ttgaaacaga tcagtctaat acagatatta
    13981 ttgcttcagc tttaacatgg tataaagaga aaaataaagg aaaagcataa aagatcaaga
    14041 agggggtaag tatatgaatc gtgatcaata ctctcacaaa gaagataaat atgtatggga
    14101 aaatatttta attttagcag ggatcgtttt agggacaatt cttttggctt attttattgt
    14161 aattcctaac ttatttacat ttataaattg gtttgttcca aatttttggt caatatttgg
    14221 ctatataatt atactatgga tcgcatacaa aattcttagt tttatttggt ttcctgtata
    14281 ttctattctt ggaaaatggt cgtatttgat tttacttgca accttgatct atatttttat
    14341 gcagatagcg tagtatgaag gtattaaatg atataaaggc aaattttgga gtaataactt
    14401 ggtacacgat aatgttgatt ttgtgtaaca ttacgctttc gtggattcca agttttttta
    14461 ttaatcaggt taactacaat caaggagaga cttcttttag tagttctgtt ttgttaataa
    14521 gcggtatttt tgctcctttt tttgaagaaa catttatgag agggatattt cagaattggc
    14581 tcgaaaaaaa cataacaatt ccgctttggg ggatatatgg aattgtcgca attgttttca
    14641 gcgctttgca tatgcagttt tactttgttc cttttttcat tacaagtatt ttattatcat
    14701 atgtttatga tcgatcagaa aaaaagttag tggttccatt tttaatccac agtttgtata
    14761 atatatttgt cattgtgata agcaatattt ttagtcatta agatagctaa gagctgataa
    14821 ataaggcttt ttggctatct tttttgtcta tctggttgat aaaaactaat aggaatggta
    14881 taatgaattg taggctaatt aagtcttgaa taataccgaa ggagttgaaa gaatgacaag
    14941 acgaagtatt aaaatcgagt cagctgaacc gaatttgcaa acacctcgta cttcaaaaat
    15001 tcagaattca aagaaaaaaa ctaaaatctt taagtctgaa gatgtggtaa gagtagcgtg
    15061 gtcggttaaa acgtttgacg aagatcggta tgtaaaagtt tctatgaatg gtctttttgt
    15121 tcagctaggt aattttagta gctttaaaac gattgatgaa ttatatcccg aaattagaaa
    15181 tattgtggat agcaagggtt tgatcgttgc aaaaagaaaa tctagaaatt caggacttgc
    15241 atattgtaag gataagggaa ttatgattcc tgcttaatta gctatttgtt ctttgaaaat
    15301 tgaatattac tcgctctgtg gcaatattgc tatgtcgcag aattaagcgt aaggctaaca
    15361 agcaaaatag caatcgaagc atactgttat ttctcttgcc atgaggtcga aaaaaagacg
    15421 atagcgatag aaatgataag gtttgtattt cacgccaaaa aatgcataag tcgatccatt
    15481 tgaaccttct aatgacgagg tggtgaaaat ggcatttatt aaaaatattg acactaaaaa
    15541 attcagcgct aaaacaagag tgctagacac aagttaactc tttactacaa gaaatgtagt
    15601 aaagagttgt tacaattctt tattacattt ctttcaaagg aagtgtgata atgaaaaaaa
    15661 ttaaactgat tagcgttgct ctgttcagtc taattacttt atcaacggct caccaatcgg
    15721 ttgcttcagc tgaaggagcc aatagcgaaa aagcagtggt agaagaatct ggtgataaaa
    15781 aagttgcaat agacgacaat gttaaaaatg aagcagaaaa agctgctgtt gttcaaggtg
    15841 cagatgggtt aatgtatgtg gtcgttgatg aaattgatcc aaaaaaacta cttgaagccg
    15901 aatccccttt gaacaatgaa caagagaata ctggttctgt tgaagtaggc gttgataaaa
    15961 agcggcaaga agaagctgat caggcaaacg aaaaagtaaa agattttgaa gatgttgatt
    16021 ataacgatat tagttccctt caatcagcgt taaataaccc taaatttcct tttttgtctg
    16081 atgatgactt aaaagaacaa ctaagtaaag ctaaagatac atttgagtca gaagaattaa
    16141 ttaagaaaac aagaggatat ttcagtcaaa ggattttaga attagggaat aatttaaatg
    16201 atgtaccaca aagagcgaaa gtgaatcgtc gtgctttagt tagtacccgt gcttcaaaag
    16261 taagtgaaac acgaattaac ccaccgagtg ggtatccgtg ggtaatttat cttgttagaa
    16321 gtaatggata tagttacaca gaaaactatg ctatcagaag aactattgat gggaaagaag
    16381 cattttgttt gcaagcaggt gtgacagcaa cgaatactta cacgggttcc gcaagtggct
    16441 atctttctaa ttctcaaaag gaattgatca gctcgttttt gtctgcttat aaagaattag
    16501 gtggatgggc caataatgat tctggaaaac aaagatggat tgcaacgcaa atacttgttt
    16561 gggaaaacag caatgaaaag cctaaaagta taactgtaac accaaattgg aaaagtgggg
    16621 ttactaaatc aaaaagtgat ataacagctc gtgctaatac gattcgggtg aaacctactt
    16681 gggatgtgaa ctctaaaact gtgtatgaag gagaaaaagc gacatttaca gttaagaaca
    16741 ctgggggaga gcataaatta aaagttgagt ctgtcagtgg tggtggaaag gcgactatca
    16801 gtgggaataa acttacagta gatacaagtg gttctacagg tacacaaatt gttgttaaaa
    16861 tgacaaaggg atctactgaa ctaaatccta caactgtttg gagtaatgga tcttatcaaa
    16921 aacttgttac aggctctttt tatgttaata cgtctgttac tgtgaatgta aaacgtaaag
    16981 gtactgtaga ggttctaaaa attgattcag aaaccaaaaa accgttagca ggagcgacat
    17041 ttagattcag ttattcgggt atcaacaaag atgttactac tgactcaaat ggtaaagcaa
    17101 aattgactga gcgtttgaaa gccggaactg tagtaaaggt taaggagata aaagctccta
    17161 acggctatca attagattca agtgaatttt caattacggt taaagagaat caaaatgtta
    17221 ctactacaag aaccaacaag aggtctacag gttctgtaga aattgagaaa ctaggcgatt
    17281 tagatggatt aggattgcct aatgtagtat ttacgattta tagttccgat aacaaagttg
    17341 taaaagataa cttaaaaaca gatagtaatg ggaaaataaa agttgatgaa ctgcaatttg
    17401 gtaaatatta tgcagtagaa aaacaaggtg tcactggata tgatcctgat ggaaaaaaat
    17461 acaattttga aataacccaa gatacaccta gtacaaaacc agctaaagtg aaggtaacaa
    17521 atatttatca agtatctata agcgaaaaag tatcggatat gaatgaaagt caggtattaa
    17581 aaaatgtttg gtctgctgat ccaaacgatt atcttcagta tgacattaca acgggaaatc
    17641 taaaaaaatc cggagaaaga aatgtccaaa gttttattat cgaagggttt tacgataata
    17701 aaaatgtaga tgttttaaaa agtgaagtat acgtgggatc aacaaatgtc acaaactctt
    17761 ttgatattag taacgatact ggcaacggaa aagtaactgc caaggcgaag gcaacagtgt
    17821 taacgaataa tgatttttat aataagtctt ataatttacg gatcactatg aagataaaga
    17881 aatctactat tgaaaacact gaaaagcaaa aacccttaac gattgttaaa aatagtaaag
    17941 ttactgtcgg ttccaaaata tctaaatctg ctagttccaa cgatgtagaa acagttttat
    18001 attcaagaaa aattactatc aaccatatcg atgaaaaaga taaacacctt ttgaaacaag
    18061 atattgatta taaatatgat ggggaaacat atgaatataa acctagaaca gatttgtttg
    18121 ataaagatgg aaacaattat aaatctgatg taatccagaa ggggaaaatc aatggaaaag
    18181 atatagtttt aaccactcct tatcatattc cggcactttc tgtgaatgtt gatcggattc
    18241 aaattgatac gtctagagct gttaaaaatg gctttttacc tacagaatta gaactaagca
    18301 aaaaggaaga atacggaaat gagctgtcaa agatcgtatt taaagtgaaa atcacagata
    18361 tagacagcaa taaagttgtt tatgataaca actttaaata caaagaattt agtagtcaca
    18421 taaaacttaa tttgcctaca gaatatttaa cgaagaataa aaaggtaaac tatagtatta
    18481 gtattctatt agttgaaaat ccagaaaaaa ataagttcga tactgaaaca aaagacttga
    18541 aaacgatagg atatacttct tctgaaaaag ttctaacaaa caaagatatg acaaataatc
    18601 aggtcaacta ttcagcagtg gttagaacgg tgaaggaaag agcaaataat aatccggtta
    18661 aagagttccg tgaaagtatc aattataagt ttactgatac taccaaaacg aaaacaggat
    18721 atggtatatc agttgattta gagccaacat acaaaaatga aattgggaaa caaatagata
    18781 tgaaagtcta tagctatcca atgaacgaat taattgatag taaaattgac gaaatctatc
    18841 aaccaattgg ggaaaaagaa gcagaagtta agatggatcg cttaaaaaat gaaagtaaag
    18901 ttgagtcggg tactaatact caaattcttt cgttccaatt tccacatatg aatgttgaaa
    18961 gaaaaactgg aaatgtatat gctgacagtc aaaaaaatga tgaatctatt aagtatgagt
    19021 tgatcgatgg tggtagaaaa ttatatgtgc ctatttggtg cgatttgggg aaatattcta
    19081 ttgctatcaa aagtagtaac tttggtggta actatatctc gttggatatg aatcagagca
    19141 tagatgttta tgcttatatg tatgcaacga tagatagcga aacgaaaaag gaagatgagt
    19201 tgctacttga acctgtctat ccagaaacta ctttaccaga caattggagc aataaagaga
    19261 ttgactggct gaataaataa atttgtaaag ttattgtcta tctgttagaa tttaacaata
    19321 atatagaagg tagtgataga atgagggtac aaagcaccgg ctatggaaat agcgtttttg
    19381 atgtaaaaag agagtttcaa gactctcgta gaaagacgag aaagctgatt gcttatttca
    19441 ttctatctgc tatcgttttc tacattataa ggtttgtctt ggaactaaat tcaatggttt
    19501 ttgtggatat ggttcataaa atgcttaatg gtgaatcagt tgatttcaat tttgcttata
    19561 tgctagatca agctaaaagt aatcaagtgg ttgcattttt aatcagtgtt tattacctca
    19621 ttgaaaagtc tgtattctca ttaaaagaat ttctattggg tttattttca agatttgttg
    19681 atgttgtagg aaaaggaata gaaaattagt aaggaggtag ttatatgtta gatcaaaata
    19741 cagaccgttc gtggtggatg attggagcgg taattgtagg agcggtactt attggcattg
    19801 ctaaagttgc ctttcctgaa gtattcaata cagtaattga tttcttcaaa aatatgattc
    19861 ctacccgact agggtaaatc aactaaaaaa ttcacgcaaa aaagcgtagg agagatacat
    19921 aagtgattat gtatctcttt ttttgcagat aggggagtga aatattgcta agagatatgc
    19981 caaaaatcat tcttcttatg tttgttggtc tcttcatgat attaatagtt gcgtattact
    20041 ctctaaatgg ttatacgcag gattcgtcag taaaaagtat tcaagaaaca cttagaacta
    20101 ccgcaatttc caatcgtgat gatagtgttc gtatagaaaa aggacgattc attttgatga
    20161 aagatgactt tgaaaaagat tttaaagaaa agtttaacaa agggaaaaat ctaaataacg
    20221 acactaccaa gtatgatttt gattatttat ctgatggaaa agacggtatt aaagctatta
    20281 aggtcaaagt agtaagtgga aaacaaacat atcaagcaac atgtgtttta aacgttgcag
    20341 actagaggtg ggaagaaatg agagtaatag aacaagaaaa accttctcaa ccaacaaaaa
    20401 gtcttgtaaa tctcgtaaag gcgaagaagt ttattaaagc ggaaaataat ataagtgtaa
    20461 aggatgaaga tttccttcaa actcttttag aagatgatac tgctaactac aatccgccaa
    20521 ttgaggaagc aaggctgaat atgattcgtg atgatcttac aagaaattac tcagaagaag
    20581 ttttacaagc actaactgac gatgaaatcc gcaaaaaact tgtagaagtc gtgttgaaag
    20641 aacacggtag cttattcaac aaggataaat ctcgtgaggt cgctgagtat gttgttcgtg
    20701 aatgtatcgg aacaggcatt atcgaacgga tcatgacaaa tgatgatatt actgatgtcg
    20761 gttggaatgg ttcacaacta agtattgaaa caaatagcaa taagtggctc attgacggtg
    20821 aaaagctaaa tattacacaa gaatatattg aaagggttat ttcaaaatat gcggttgtaa
    20881 acgatcgaga ttttaatacc ggtaatccaa ttctggatgg gatgtttaaa aatgtgcgta
    20941 tatcagctac acacatagat aattcacctg acggagctac aatgtctatg cgtgtagcaa
    21001 gaccaaaact agcattgaat actacaaatt ttgagaattt tgctccggat tacattttag
    21061 atttgtttga aaaaatggta aagacgaaag caaatatttg catttcagga gaaactggaa
    21121 caggtaagac ggaattacaa aaattgttac tgagttttat tgataatcat gatcgcatga
    21181 ttatgattga ggatgttcaa gaaactcatg caaaggaact attccctgat aaagatattt
    21241 atgcttggat cacaactccc aaaaagacaa tatctgattt agttaaggct tgtttacgta
    21301 acaatccacg atggattatc gtatcggaaa cacgaggagc agaagcctat gaaatgttac
    21361 aagcaatctt gtccggtcac catgttatta caacacttca cgcaattaat gctcgtgcaa
    21421 ttccaaggcg atttgtcaat atgtgtgcga gtggttacaa cataaatgaa acagcggtgg
    21481 aagaagatat taaccgttat tttgattttg gagttcatat taagaaggtt gtgattaatg
    21541 gaaaagttat tcgataccta aatgaaatcg ttgaattttc agatactgga acaacaacag
    21601 ttttcaagca aaaacttatt aacggtgagt ttataaggga aaatggtgca ttgtcagatg
    21661 attttaaaga aagaatggcc gaaaaattta tctcgtttga atttccggaa gataagatag
    21721 aaaaagaaga tagcgaaact aatgaattaa atagcgaaaa ttcagaggtt gaggtgatca
    21781 catgaaggta caagcagtaa caaagaaaaa gggaatcatg gatgtttcag aattaaatgc
    21841 gtatcaagtt gcgtatggaa aaccacttga ttatcgagat tatctgaatt atgtaggatt
    21901 accttgcata ttcatgggtg tattctcatt ttctctttgc tatttttggt gggtgggttt
    21961 gatttgtgga gtgattggcg ctgtgtatgg ctataaggtt gttatgccaa aaagtgtaaa
    22021 gcgatcttat gaattgaaga gtttgagaga aagaaataag ttcattaaca atatgactca
    22081 aatcttgacg gatgaaagta agacagtaac gaaagcatta gcaatggcaa aaacccgaac
    22141 caaaggagaa ttaagagaag atattcaaat tttagagtct cgattacaag gagctgacaa
    22201 gtttcaaata gctgaagcat ttagagaaat aaacgaaaag tatgaacgtg acgttgtgtt
    22261 cactcaatat tttgagcaac ttgaaacagc aatttatgaa ggtcgaaata atgctgatac
    22321 gatgaagcag attaaaagtt atcacaatga tgtcaagcta aaaacagaga gctttttaaa
    22381 aatcaaagat gggtatcttc aagatttaaa acagatgctg ttcatagtag caatatttat
    22441 cggagcaatt acattttcat ttggattttc aacatttttt gatggttttg ctcgatcacc
    22501 gatcggttgg ggatttggcg gtgtttattt cattatcatg gtacgcttca tgaagtcatt
    22561 cttcatgcat tactttgatg atgaaattat gagcttgggg gtgagtaatt agtgaaagta
    22621 gctaatgtac aaaaaaaagc ttccaagaaa gcaagaataa ttaagcaaga gaataaatca
    22681 atctggctta aaatgttaga cgaaaattat tataagaaat tacgtgaaat gaataactca
    22741 aatgtctcaa tcataaagtg gcagaagcaa aggtttctta aatcatggat attcgttggt
    22801 gttggattag tcatgtattt gcttttaggg aaagaatggt attacctagc aggtggtata
    22861 gctacagcaa tagggttcta cattatacaa gcaaagtcaa taaacaatat ttataatcaa
    22921 tttcgttttg aacgacactt gcaatttagt aaatttacaa gattacttat tccgtattta
    22981 aaacagaaaa aagacggtgg taatctttat ggtgtctttg caaaaattgt taaacgttta
    23041 gattatgaca cggataagca actattgatg aaattaatgc aggatatgac agatcgtcct
    23101 aatgatattc agccttttgt ggaatatgca gagcaaactt caggaacaga catgagtgtg
    23161 ttgtttatgc aaacaatata tgatattcgt cagggttcag cagatttaga tgtaattgaa
    23221 gaacttgatc gtttagcttc tgaagaattg atggccggta ttgattcaat tattgatttc
    23281 aaaagtcgga gattcgtttt ttatccgaca aaaatagcta tgacttcctt tattcttgtg
    23341 gtcgggtttg ctgtaggtgt tctttttctt aacttgaaag acataaactt tggtcaataa
    23401 aaggaaggaa gaaaatatat gcaagaacaa tcaataatgg agatagtcaa atggtttata
    23461 ggtcttgtaa taatcatggt gatggtgtct gttggtttat tttgctacca gcttcaagat
    23521 gtgaatagtt ttaaacaaca ggtaaattat caaatagaaa gaaggggcgg tttaacagct
    23581 gaagcattaa aatcattaaa agaatactca gataaaaatt atcaaggacg ctataaaatc
    23641 gaaagtaatc ttttgaatca aaaagtagaa tatggccaag ctgttgatta cactgttaaa
    23701 gctacaatcc caattcaaat tttaccatta ccggatgtta cgctttcatt tgaaggaaat
    23761 agtgtgtcac aaatcagata agaggtggta atagtgcaag aaaataatac tgcaagaatt
    23821 ctttttctaa taggcggaat ggtaatctta tcactagtta tcactggaat agctacacat
    23881 tgggaagaaa tcaaatcgct gattgaaacg ttcttccaaa ataagatgat acgaatgtga
    23941 ggggaaatag tatggatgaa actgtagaac aagtaaataa gccaaagcga caaagaaaga
    24001 aaaaggttga tccttttatt gaaatgacgg acaaaattat tcagaaaaaa ggattaactc
    24061 ctagagagtt cgatcagaca gcaattagaa aagaacggca aaagctttat gatgaattcg
    24121 ttaaagaaaa tattggatta cttttagact aaatataagg ggcgctttaa tatgaaagaa
    24181 attatgataa ctaaattagc aatgaatatg ccaaaaatgg actttttcga taatgtatca
    24241 aagtttatgt caaatactac gtctaaactg caagggattt ctctttcggt aattattttc
    24301 tgtgttgtag taacaggaat gatgtttctt tttggggaag ggccaagtag aacagctaaa
    24361 aagtggctga cgtatattgt tatcggagct ttaatcattt ttggtgcttc aacaatcggc
    24421 caaacaataa aatctgttgg tggattctaa aattaatagg aataaaggag cattgagatt
    24481 ataatgctcc tttttaattg aaaaaaatga agtagagaag gagaaaagta gatgaaacaa
    24541 cgttttgaat actcatttga agatgtagaa tctaaattat tacgaaaagg gaaaggctta
    24601 aaaaagaaaa acaaatattc attaaaacaa gcagaaggct tgattgcttg ggtacaacac
    24661 aactggccaa ataaaacaga agttactgta atgtgcaaag ataccgaaga tggtgctgta
    24721 tatgcgtttg atgggattga aattacaccg tttggtatgg ggggagaacc aattgcattg
    24781 tttcctatta ttgaggatca aattctacag gctccggata atatgattaa tgatcctaat
    24841 aaattgattc tagacattaa tagccaatat cagtcagagc cagatatagc agaagcgaaa
    24901 caagaaagta agtccaaaaa agggttaaac cttccaagcg ttcttccaaa tgtcaaatta
    24961 ccttttggaa agaaaaagca tttggaggaa acacctgaaa gtgatcaatt ttttgaagaa
    25021 tacgaaacag aaagtacacc agaattagat gaggagcttg aattagacga agagtctgaa
    25081 gaagttgaag cggaaatcga aactgatctt gaacaagctg aggaaacaat gttagatgaa
    25141 actgaatcat tcgattttga ggaagaaatt gacatgacta caagtagtca tgagagtgtt
    25201 gctattaatt ctcaaacttc tgtgcctgca tattcacaaa acacttatca tagtgagcaa
    25261 aattttgcgt tagccagttc tattccacaa acggttcgac aaattaaaaa gcatgaaaca
    25321 gtccaattaa ctccattaca agaatattgt gatttaggag aagaaattga atcctctatt
    25381 gtatcaacaa ctaataaact tcagccagaa aatctgttta aatttattgg tataccagct
    25441 gtaaaaaata cgcgattaga tgaatacaga atcaatcatg ccatgcaacg attagctgag
    25501 gttaagtttg aaaacttacg agaacattat tctcgtcaag ttaattcaat gatagcagaa
    25561 gctttggaca aactacgaga agctattgat gtggcatgga aaaagccata tgaccttgag
    25621 gtgaaaaaac ggtatgctga cattttagaa gaaatggaaa ctaattctaa ctccacatta
    25681 gaggagtttg taaaacggca atatgatatg gtggatgaaa aaatcaaaaa gtttgaaaca
    25741 gaacaagaaa ttgcacttca aaactttatt gctaatcaag aagctgaaaa agcagtcttt
    25801 attgctaacg agaaagagcg tgcgcaaaac ttaattgata caaaatcaga gactattaca
    25861 agtgaattag aaaaacgaag agaagaattt atagatgaag aaatgtacaa aatgaaaatt
    25921 gacatgaatc aaaatctatt cgatggaaaa agattaatta agcaagagtt agcagttgaa
    25981 ctagctaatg ccaatgaaga tgtatgggaa aatgcactga aatttattac tgaaattcaa
    26041 aatgaaatca acgaaaagac accactttgg gcttctgaaa ttaaagagac taacatttta
    26101 gaacagcaag cacaccaaat gcaaaaagaa caacaggaac taaaactgaa agaagagtca
    26161 ttggctatta aacgtttaga agccgaaaca aatctgaaac gattagaaga acttgatcac
    26221 gaaaataaaa tgttaaaaat caagttggaa acagcgaatt ctaaaaatga actctatgaa
    26281 tatgagaagg aaacacagca aaaagttgtg gggtcaactc aagcaagaaa tttgagtacg
    26341 ttgggattgt ttagaaaata atcaactaag gagactataa atgagtgtat ttaataataa
    26401 aaacatggtg tcaggttatg tgaatcatgt tgcggtatat gatggtggat cttttaagac
    26461 aatgtttgtt cgtttagctg tttttaacta tatgaaagag gataaagcac agtacgaagt
    26521 aatcaatgca caaatatctt gtagtgtaga tcaacaaggt aggctaacga ctacaagtag
    26581 tcacccgaaa gcgctgttga ataaaatgct tttcgataaa ctagataaaa atttagtgga
    26641 aggaatgaaa gtaactttgc atggtagttt gcgtggtagt gatcaagttt tcttaagtgg
    26701 ccggtggcga aattttaaag atttatcttc agctgaaaaa gaagaatata agtctttgcc
    26761 aaaaggtcaa ttaataacta gaaccaattc ttttatttat atagaggaag taaacatgcc
    26821 gagcaaggaa ggttttttga aacgtaaaga ggaactacta acagaaaatc aaatgaatga
    26881 agtaaaagtt acagagccta gtcaagctga tcaaatggaa acagatgata atgaccctgt
    26941 cgataatgaa ggtgttgtag ttgaaacagt agaagctgaa attatagaac cgcaagaagg
    27001 tactaaaatc tctcgtagaa atacagtgtc ctacgtacga ttcgaggaca tgatttaccc
    27061 tgaagccact atggtggaag aagattaccc tttctaagtt atacgaggtg aaaaatgaga
    27121 cttataaatg ataagaaacc tgacaataag ttaaaagtat tgttagaaaa aggaaataaa
    27181 attgaaatcg gggatatgat gtggtttaaa ggaaaaaata aatatcatag cggaaagatt
    27241 gaaggggaag atttacctga aaatgtaaaa gatatggtta atcttccgtt attgttgcta
    27301 ggaaccgttc taggactctt tgcgaatctg accgtaaact acttaatcaa tttttttgca
    27361 gctttcctga aggctctgag tgtttctgag aaaggattaa tgagcattga atttgatcat
    27421 ggattccata tgggctatct aaaaccattt accagtggaa ctcaatattt tatgatttcg
    27481 atagtcgtat gtatcgcaat aacatttcta gtttataaca aattagatca tgaaagtgac
    27541 agaaatcttg tatacggcca aaagggtgat tcgagatttg cgacagtaaa ggaaattcaa
    27601 aatgaatatc atgaaattcc tgaaaagaaa gttcgctttg aaggaatggg tggcgtacca
    27661 atctcacatt ataaagataa gtattacatt gaccgtgata cagtcaatac agttgtttta
    27721 ggagcttctc gttcagggaa aggcgaaacc tttgttgttc caacaataga taatctctca
    27781 agagctaaag aacagagcaa tatggttgta aatgatccaa aaggagagct gttttcagca
    27841 agtaaagaaa cattggaaaa aagaggttat cgagtattag ttctaaatat tgatgatccg
    27901 ttacaatcaa tgagtttcaa tcccttgcaa cttgtaattg attcttgggc gaataaggat
    27961 tatcacgaag caagtaaacg tgctaatacg cttacgtcta tgcttttcgc ttccggtatg
    28021 ggaacggaaa acgaattctt ttacaaatca gctaaaaacg ctgtcaatgc aataatttta
    28081 acaattgtag aacattgttt tgataataat tgtattgaaa aaattactat gtataatgtt
    28141 gcgcaaatgt tgaatgaact aggaagtttg ttttataccg atcctaagaa tccaaataaa
    28201 gagaaaaatg ccttggatga atacttcaat acattaccac aaggaaatca agccaaaatt
    28261 caatatggtt caacttcctt tgcaggagat aaagccaaag gctcaattct ttctactgct
    28321 tctcaaggaa ttgaaatgtt taccagtgat ttgtttggaa aactgacaag taaaatgtca
    28381 attgacttaa aagagattgg tttcccgaag tcacttcaat tcaagctaaa cactgaaatg
    28441 gttggaaaaa gagtaaaaat ctcattttta agaaaaacag atggcaaaac aaagataatc
    28501 aatgaatatc gagtaaaagt taaagcgtta ggtttatgtg tgttaaattt tgacgaaagc
    28561 ctacgagatg gcgattttct cgaaattcgt tatgaaacag aaaaagaaaa attcagagca
    28621 tggtatagcc ttgaatttcc taaaagggat tcagaagatc acgatacaac agtgatcacg
    28681 aaaaaattca aatcaggaaa aagattcctt gatttagaaa tcaattcagt cgttcttaaa
    28741 tatactgatc aacctactgc tgtttttatg gtaataccag actacgatcc aagtaatcac
    28801 gtaatcggaa gtattttcat tagtcagcta tatacggagc ttgcaacgaa ctgtaaggaa
    28861 actcctagta aaaagtgttt ccgaagagtt cattttctat tagatgaatt tggtaatatg
    28921 ccagcaattg acaatatgga tgggattatg accgtatgtt taggacgaaa tatactcttt
    28981 gacttggtta tccagtctta tagtcagtta gaaagtcgat acgataaagg cgcaaaaatt
    29041 atcaaggaaa actgccaaaa tcatattctg atcatgtcaa atgatgacga aacaatagaa
    29101 gaaatttcaa agaagtgtgg aaataaaacg atcataggaa aaagtgctag ttcaaaaaga
    29161 atggatactg atagttcggt cacttcttca gcagatcaag aaagaattat tacttttgaa
    29221 cgtgcgagtc agctaattga aggtgaacaa gtaattttgc gtaatcttca tagacaagat
    29281 aaaaaccgaa aaaaaatcag accttttcca atctttaata caaaagcaac taatatgccg
    29341 tatcggtatc agtttttaaa tgatgatttt gacacacgaa aagatattaa cgaaattgat
    29401 atagcgtgtg atcacattaa tctatcttta gctgataatc aaattccatt tgcaagcttt
    29461 attcgtgatt taaaaacaag aatggagtat tcaattacaa atgaaatact aatatcagaa
    29521 gatgattatg aagaatatcg tagtttgccc aattcacaac aaacgcttga tgaagagaag
    29581 ctaattggat tggtgaaaaa atcaaatttt gagaaaaaat cagaagttga gctatcagaa
    29641 gatgatttca aactaactac ctatctttta gattgtcaaa aacatacaaa aaaactacat
    29701 gatttaatgt atgagaaaga tagatttgct gatgataaat cccttgacct agtgcttaaa
    29761 acgctaaatg aaagatattt ttcttcagag ctggtacaag aatttcaaaa aggacgggtg
    29821 actgctcaaa atatcaagca gtccaaaaaa cagctagcag ggataatcaa tgttttagga
    29881 caggtatata tttatgccga aaacaatata ttcaaaacgc atattatagc cgttaagaac
    29941 gcactaacaa aattaagtaa ggctatctga atatgaagga tgtgaaaatt tttgacagaa
    30001 gcaattttaa caagagctaa tagaattaaa ataagatggc ctatggtact tttactagcg
    30061 acaatattgc tattcgttat ggttcccaca acagcgtacg cgtggccgtg ggattcagat
    30121 gataaagaag cattagattt tttgctgaag tatcaagact atttacagtt tacaaaaggt
    30181 ggctttggaa gtattgtcat gcaaaccttt tcgtggggaa taattcgatt tgcgtattgg
    30241 atttcaaaaa ctatcgaagg gttgataccg caagcgttaa gtttatttag ctttgtggaa
    30301 agtgctggat tgaacaaagt ctatcagtca gttttaaata cagttgttgt tgggttaatg
    30361 gtactctcac tagttattat tggatataaa atggtgactg gaaaagggac tttagactta
    30421 aaatcggttg gaatgaacgt agttatgtca gtagcattaa tattattaat gcctactatg
    30481 atttcaagtg gaattacgtt tgctaaaacc ttttataatg acgcaactag tattaacaat
    30541 caagatggcg gtgtggcatg gtctcttatt gaagatggag tgacagattt agtatatatc
    30601 aataaaaatg acgcttataa tcgcatgggg aaagaaggcc aaaagaaaaa tgcattaaaa
    30661 gagaaagatt tttttactta tgattttagt gaagtaataa cgactgacac agcgaaggaa
    30721 ttagaagcag ataatcctaa agcggagtat ttaaagatga aattgactcc tgatggtgat
    30781 ggaaatatgc aagccgtaaa aattgatgat ggatggatgg ccattttttc tgatagcttt
    30841 aagggaggtt attatagata cacgaaaaac acgtttgcgt taacgttggg cttaattgca
    30901 ttggcaatag cgtatgtttt tagtgctttc attataatta cagcaatact cgagttagca
    30961 tttaaacgtg tactcggagt tttagtattt gctactgact tggaaacagg ccaacgatca
    31021 aagcaagttt tgtcagatat tttacagtgt tatttgacag tcggatttca agggttcgga
    31081 ttgtctatgt ttgcaatgtt tgttaattat ctcggaacag gtagcggttc ttctgtaaat
    31141 ccttttataa aagcagtagc gtacgtctgc gctgttattg tgctgataaa gggtagtgga
    31201 acagtcatgc gttactttgg cgtggatatt ggtttaaaag aaggctatgg ccagcttgct
    31261 tcagcatttg gcatgggagc tatgctgttt cgtaaaggaa caggtggtat gaaccgatct
    31321 aaaggtggga aaaatagtgg tggaaacgat caagcggaag gggaagaacg aaaacctgaa
    31381 cgcaactttg gtcaatcact ttctcaaaaa gctaataaaa cggggaaaac acttgggtat
    31441 gctcgtgaac gaggattatc aggcttagct tcggatggag ctacaatggc cagtgaaaga
    31501 gcaacaaaac catttaagag tatgcgtgat atggctaatg ataccaagaa taaattcaaa
    31561 gaaggtttag atgatggtac cgtgtccgct attaataaaa atagcaaacc tatagtagct
    31621 aaaaacaaag aagatgaaac tggaaaatat gctgattcta tgccaacacg tctttcggat
    31681 agaaaagatg gcgctaaagt tgaaaacgct gatagaatta tgtctagttc tgaacgtatg
    31741 cgtgaagcaa tgaaaaataa tgctgaatca aatattaatc ctgcaagtgc aattcagcaa
    31801 aaagttaaac aagatattga agaacgtaaa aatgctatgc acggtcaagc taagtctgct
    31861 gaagaattaa ttaatcagaa gcgacaggaa gcaaaataca cgcctgaagc aatgaatcgt
    31921 gaggaaatgt taaggaaacg tgtagaaggg cgtacaggcg ctaatatgga cgaaaaagaa
    31981 gcgttgacta aagaaagaat ccaagaagct aaaaattcaa ataccggatt agaaaaatca
    32041 gtcaaagaaa atctacaaaa ttctacaagt agtcaagata ggcgctcagt agatgttcga
    32101 gaaaacttac aaaatactac aagtagtcaa aatggaaatc gaacagtaga tgtacgagaa
    32161 aatgtacaaa gtagtgggac aagccaaccg agaacggtag atgtacgaga aaacttgcag
    32221 aatactacaa gtagtcaaaa tggaaatcga acagtagatg tacgagaaaa tgtacaaagt
    32281 agtgggacaa gccaaccgag aacggtagat gtacgagaaa acttgcagaa tactacaagt
    32341 agtcaaaatg gaaatcgaac agtagatgta cgagaaaatg tacaaagtag tgggacaagt
    32401 caaccgagaa cggtagatgt acgagaaaac ttgcagaata ctacaagtag tcaaaatgga
    32461 aatcgaacag tagatgtacg agaaaatgta caaagtagtg cgtcaaatca accaagaacg
    32521 gtagaagtac gtgaaacaag agctgaagca agtcagggag ataagacgca aaaaataaat
    32581 attatcgagg aacgaaaaga aaggcctaac gaaaaagtga ttgtagaaca agaagtgaag
    32641 gagaagaaac gtccacgatt tacttatgaa aataatccac tgtttcagga tatttctgat
    32701 aaaccgaatc cacttttcga taatctattt aaaaaataaa aatgaggtcg gcatagcgtg
    32761 atatgtcgat ctttttttga ggtgaaagaa tgtatagaaa tcctaaaaac ataaagcaag
    32821 aaataaaatt gttctttttc tacctagtag atttaggtat tgtagcaggg tgtgtaatgt
    32881 gtagtgttta ttttgcaaaa ttaatgccag tttctccttt gatgaaattt gctttttatg
    32941 tccttgcctt tattgtaggt gtttggatgt gtgtcagaac acctaatcac cccaaagaaa
    33001 gaaatatttt gatggtttac tatctgctac gaatggatcg caatagatac catgaagtgg
    33061 aatttaaaag aaataaaagg gggaaaattg aagtatgatc attgcagaac cgaatgagaa
    33121 taaactagca gggttgtttg ataaactttt agatttagtt gtgccaaaag ataaagatat
    33181 gtgtgaactg ttaccatata aaaaagttct aaaagatgga atccttgtta ccaatgatga
    33241 taaatttcag gttctattta aggttaaaac taccgatctg acgtcaattt ctgaagatgg
    33301 gtttatgcgt atggtaaata aattgaccta ccttaatcga gtatatttag aaccatacaa
    33361 aatttattct cttacttatc ctacagaaac tattgaacaa ggtatttact ggaaaaatag
    33421 aattcaagaa gctaaacgtg aactgataaa taattctgat ccttatttag aaccatactt
    33481 gaaatggaat ttaaaattgg catatgacaa ttacgaaaga gtagagcttg tgtcaacgtt
    33541 gccggaattg atgtttgtaa ttgctatata tggaaaaacg attaaagaag taaaaaacca
    33601 cgctgatgtg atgaaacaag ctggtggtag agaattagat ttacaacgaa ttaatgaaga
    33661 ggatttaacg aatgttatta ctaagttaat gaatccaaat tcttcattat agtggggtga
    33721 aaaaatgttg aagaaaagtc ggaaaggttt aaaacattgc ataaaagaaa atggagaaac
    33781 gagattttat gagtggaaag agcctaattt aattagagtg ttaggaaggt tcgatacaac
    33841 aagtagcgac ttgctagaga cctgtcgaaa taacaagtct ttgattgtta cgaaagacac
    33901 agctaaatat cgaggaataa ggtgcattga aaaagaatct gttggtgtac atgacattaa
    33961 aatgatcgag gacatattag aaatctatcc tgattacagt ttggttgtgt acgatgaaac
    34021 agtaaaaccg gtgaatcagt gtgaatttta taaggcgtta gtaaaaataa ctaaaagatt
    34081 tgaaaatgtg atatttatat ggactagcaa aatatcaaca aataaacaaa gcgaaaagac
    34141 gttctttagt gacaagaacg tctttttacg ttctatttaa aggagagaga aacatgattg
    34201 taaacagaag tgtagctaga aaattagatg gtgaaggata tgatctgaga tttgtagaac
    34261 agtatcaacc taaaggcggt attaaatttg acgagcgtta tatcacggtt ggggacggct
    34321 atctgagttc tgttatggtt attgaatttg ctgaagatgt aaatagtcga tggctaactg
    34381 atattatggc aattcctgac actatcgcaa catttgatgt gtgtactgct gataaagaag
    34441 atttgctaca caaaattaac acgtcgattg gtgagttaga ttatcgatca agtaatgaaa
    34501 atagaactac agataaaacg gacgctcttt tagataaata taatttagaa gaatttgctc
    34561 aagaaattac caagcgagga gaagtagtta agacagttca tgcgagaatc tttgtatata
    34621 acgattcgct tgaggaatta gaaaagaaaa tcacggaaat tcgcaaagac ttagctagtg
    34681 tgaaccacaa ggctattgtt ccgcaattca ggatgaaaga tgaatggctt tcactattcc
    34741 aaagtggggt tgatcaagaa gcacaattat ttgctaaaaa gggcttaact gtcccttcta
    34801 gaaatattgg tggcggaatt ccctttcacc ataaaagttt aaaagaccca cgaggttttt
    34861 acttaggaac gacaagtacc ggtggggcat ttatctttga tccatttttt tccacaaaac
    34921 aaagacgttc tttcaacggt tttattcttg ggaaaatggg attcggtaaa tcaaccttga
    34981 ttaaacagct acaagaaggg ctacaagcga agaattgctt tataagagga tttgataagt
    35041 cgggtgaatt cgaaggcatg gtacggcaag caggaggcgt ttacgtagat ttgggcggtg
    35101 gagatatggt tgtgaatccg ttgcaagtat acgctacagt gatgaaaaag gatcagtacg
    35161 gaaatgacgt gatcgatgaa gcaaaaagct ttcaaaacca tattacaaag tgtagtaacc
    35221 aaattcgatt tttggagcca ggaatcgata cagcaacggt tcgtgaatat actttgatgt
    35281 tgcaggattt ttatattcaa cgaggaatcc taccacaaga atggagagaa gcaaaagatg
    35341 ataatgagag aaattcatta ggaacaaata tttgcaatct accaaacgaa gcatatccgg
    35401 tctatggcga atttttgaat tatattgaac agcaacaatt taacattcaa ggggctacac
    35461 cagagcgtgt tcgttcaatc gagttgatta aaatgattgt gaaagatatg tgtaccacat
    35521 acccacaaat ctttaatggt attactacta tgcctaattt tgatactact aaaattgttt
    35581 attacaatat tgattcaatc agcaaaatgg ataaacctgt gtttcattgt caattattca
    35641 cggcattaac aactatttgg aacagtgctt taagaaatgg gaaaattcaa aaagaaaact
    35701 tcaaaaagca tggaagtgat tactttaagt atgcacaaga ctttatggta ttaattgatg
    35761 aatgtcacaa tggtgcgacc tgttctgcag tgaaaagctg tgggttgcaa gtagtctaaa
    35821 aactattgta ataactctta taacgagaag tcaaatgagt gggtaacgcc acaaagggct
    35881 tccactgata ctccgacatg caacaagtag tttatgcaga ccaacgttgt gtgaagctcg
    35941 gtgaagtcgg ctgaaggata ccgtaaggta aaagaaatag tgaataccac gaaagttctt
    36001 tagaggtaaa gggtgtatcc gataagtcgg gtgtccaaaa aaacttaata tggtgagtat
    36061 gtacaaacgt actgacgaac tagcgaatgt actgtccgaa aggcatagct cctagaaatg
    36121 ggagagacag tgagcaaaaa atcactcatt gtgctaactt gtggttgagt aaaagtcgtt
    36181 gttatgaaag accatgctgc gttacaggcg taggagaagt tagggggcaa aagctagcat
    36241 ctaagttaag gcatgtggat agatataagg gaacagggga agccatcaac atggagagtg
    36301 catactcgat gaagtggtag taagaaatat gtgaatgaca aataacttac tttagtgatg
    36361 gtgaaagtag agtcacgact gatgaaggtt ctgtaatgga actggaggaa caggctcgat
    36421 tcgtctgtaa aagtcatgaa acccgttcaa ccatgggatt ctcgtatgac taaaaaggtc
    36481 acgagccaat tggagcgtga taaaccatga caaaagaaac aagtccaaaa gataggaagt
    36541 tgcggcatgc agaatattat ggcatgacgg aaatcttcga taagatatac tccaaaagtt
    36601 tgaagggaga taatttcaag aatctaatgc agattatcat ttctgataac aacattgtcc
    36661 tagcatatcg taatatcaag agaaatcacg gtagtgtgac aagaggagaa gatggagtaa
    36721 cgattaaaga tattgaaaat ctcaaccgta atgaattcgt agaaattgtt aggaagcgat
    36781 tcgcacatta taaccctcgg aaagtaaggc gtgtagaaat tcctaaatat aatggtaaat
    36841 taagaccgtt gggtattcca tcaatatggg atagaatcgc gcagcaatgc atcttacaag
    36901 tattagaacc aatatgtgaa gcaaaattca ataatcacag ctatggtttc cgcccaaata
    36961 gatcagcaga acacgcaata gcagattgta tggcccgaat gaatcaaagt cacatggaat
    37021 atgtggtaga tgtagatatc aaaggtttct tcgacgaagt caatcatact aaactcatga
    37081 gacaaatctg gtctatgggt atacgagaca aacagcttct cttaatcatt aggaaaatgt
    37141 taagagcacc cgtagtactt ccaaatggga agttgatata cccaacaaaa ggaacaccac
    37201 aaggcggaat acttagccca ttacttgcga acatcaatct caacgaattt gactggtgga
    37261 tagcaaatca gtgggaggaa aaagatgcca aagagctaaa acatcatttt aggaaaaatg
    37321 gagcttggga taaaggtaat atctatcaca agctcagaaa gagtacaact ctaaaagaaa
    37381 tatacctagt gagatacgca gatgatttta aaattttctg tagaaattat aatgaagcga
    37441 aaaaagtttt ctatgcaact aaaatgtggt tacaggagcg tctaaagtta ccaatatctg
    37501 aagaaaagtc aaaaatcaca aatctttcaa aagaagaaag tgaattttta ggctttacga
    37561 tgaaattagt gaccaaaggt aacaaaaagg ttgttaatac gcatataggt acaaaagcac
    37621 aaagcatgat taaagtgaaa ctaaaaaaac aaatcaaacg aattcaaaaa agtcctaata
    37681 gcaaagatac ctttatctat attggagtct ataacagtat ggttattggg attcataatt
    37741 acttcaaaat tgcgactcat tgtagtgtag caatgcgaaa aattgcaaga gaactcagac
    37801 caagttttga aatacgacta cgagaacaag gaatctcaaa agaaggacaa tacggaaagt
    37861 acgaaggata caagccttac ctacggtcag gacaaatacg atatataaga gggtttccaa
    37921 tattaccagt agggtatatt caacacagac atccgatgtg taaaaaaaga aatattaata
    37981 aatacaccga agaaggtagg gaagccattc ataagaagca acaaaccgta gaagaatgga
    38041 agatatcgtg gttgtgtagc aatccagtgc ttagtaagag agcaacgatt gaatttgcgg
    38101 acaatcgaat ttcaaaattc atcgctcaaa agggaagatg tgcagtaaca ggtgaggagc
    38161 ttatcttatc tgaaatgcat tgtcatcata ttatctctta tcatgaaagc aaaagtgata
    38221 gctatgaaaa cctagtgatt gttactgagg aggttcatcg ggtaatacac gctacacaaa
    38281 gtgaaacgat tgaggaactt ctaaaatatc taaaattaaa tccaaaacaa aaagaaaaac
    38341 tcaatgagtt gagattaaaa gttggtaacg aagaaatatc ttaataaata tttgtaggac
    38401 gggaaaacag aatgtctttt atagacgagg gaacgccgta tgcggtgaaa gtcgcacgta
    38461 cggtgtggac tgggggaaaa gacggagata atat
//
LOCUS       DACBYO010000018        38103 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.018, whole genome shotgun sequence.
ACCESSION   DACBYO010000018 DACBYO010000000
VERSION     DACBYO010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38103
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.018"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            97..1875
                     /gene="uvrC"
                     /locus_tag="IVD26_000911"
     CDS             97..1875
                     /gene="uvrC"
                     /locus_tag="IVD26_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAP6078907.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            2020..2919
                     /locus_tag="IVD26_000912"
     CDS             2020..2919
                     /locus_tag="IVD26_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6078908.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            2912..4174
                     /locus_tag="IVD26_000913"
     CDS             2912..4174
                     /locus_tag="IVD26_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6078909.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            4335..6233
                     /locus_tag="IVD26_000914"
     CDS             4335..6233
                     /locus_tag="IVD26_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAP6078910.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(6563..7282)
                     /locus_tag="IVD26_000915"
     CDS             complement(6563..7282)
                     /locus_tag="IVD26_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAP6078911.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            7619..7951
                     /locus_tag="IVD26_000916"
     CDS             7619..7951
                     /locus_tag="IVD26_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078912.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            7938..9941
                     /locus_tag="IVD26_000917"
     CDS             7938..9941
                     /locus_tag="IVD26_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAP6078913.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            9960..10430
                     /locus_tag="IVD26_000918"
     CDS             9960..10430
                     /locus_tag="IVD26_000918"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAP6078914.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            10451..11035
                     /locus_tag="IVD26_000919"
     CDS             10451..11035
                     /locus_tag="IVD26_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAP6078915.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            11050..12036
                     /locus_tag="IVD26_000920"
     CDS             11050..12036
                     /locus_tag="IVD26_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAP6078916.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            12026..12337
                     /locus_tag="IVD26_000921"
     CDS             12026..12337
                     /locus_tag="IVD26_000921"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAP6078917.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            12359..14140
                     /locus_tag="IVD26_000922"
     CDS             12359..14140
                     /locus_tag="IVD26_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAP6078918.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            14133..15509
                     /locus_tag="IVD26_000923"
     CDS             14133..15509
                     /locus_tag="IVD26_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAP6078919.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            15516..16151
                     /locus_tag="IVD26_000924"
     CDS             15516..16151
                     /locus_tag="IVD26_000924"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAP6078920.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            16181..17536
                     /locus_tag="IVD26_000925"
     CDS             16181..17536
                     /locus_tag="IVD26_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAP6078921.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(17728..19122)
                     /locus_tag="IVD26_000926"
     CDS             complement(17728..19122)
                     /locus_tag="IVD26_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP6078922.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            19214..20185
                     /locus_tag="IVD26_000927"
     CDS             19214..20185
                     /locus_tag="IVD26_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAP6078923.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            20182..20964
                     /locus_tag="IVD26_000928"
     CDS             20182..20964
                     /locus_tag="IVD26_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAP6078924.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(21133..21504)
                     /locus_tag="IVD26_000929"
     CDS             complement(21133..21504)
                     /locus_tag="IVD26_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP6078925.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            21638..22081
                     /locus_tag="IVD26_000930"
     CDS             21638..22081
                     /locus_tag="IVD26_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAP6078926.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(22124..22933)
                     /gene="yidA"
                     /locus_tag="IVD26_000931"
     CDS             complement(22124..22933)
                     /gene="yidA"
                     /locus_tag="IVD26_000931"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAP6078927.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(22952..24319)
                     /locus_tag="IVD26_000932"
     CDS             complement(22952..24319)
                     /locus_tag="IVD26_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP6078928.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVIFDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(24303..25133)
                     /locus_tag="IVD26_000933"
     CDS             complement(24303..25133)
                     /locus_tag="IVD26_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAP6078929.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            25296..25733
                     /locus_tag="IVD26_000934"
     CDS             25296..25733
                     /locus_tag="IVD26_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAP6078930.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            25809..26429
                     /locus_tag="IVD26_000935"
     CDS             25809..26429
                     /locus_tag="IVD26_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAP6078931.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            26618..27124
                     /locus_tag="IVD26_000936"
     CDS             26618..27124
                     /locus_tag="IVD26_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAP6078932.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            27141..28040
                     /locus_tag="IVD26_000937"
     CDS             27141..28040
                     /locus_tag="IVD26_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAP6078933.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            28127..29011
                     /locus_tag="IVD26_000938"
     CDS             28127..29011
                     /locus_tag="IVD26_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP6078934.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(29203..29274)
                     /locus_tag="IVD26_000939"
     tRNA            complement(29203..29274)
                     /locus_tag="IVD26_000939"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(29239..29241),aa:Arg,seq:ccg)
     gene            29334..30668
                     /gene="rpoN"
                     /locus_tag="IVD26_000940"
     CDS             29334..30668
                     /gene="rpoN"
                     /locus_tag="IVD26_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAP6078935.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            30871..31908
                     /locus_tag="IVD26_000941"
     CDS             30871..31908
                     /locus_tag="IVD26_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAP6078936.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            31949..32950
                     /gene="gap"
                     /locus_tag="IVD26_000942"
     CDS             31949..32950
                     /gene="gap"
                     /locus_tag="IVD26_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP6078937.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            33060..34250
                     /locus_tag="IVD26_000943"
     CDS             33060..34250
                     /locus_tag="IVD26_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAP6078938.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            34354..35109
                     /locus_tag="IVD26_000944"
     CDS             34354..35109
                     /locus_tag="IVD26_000944"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAP6078939.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            35225..36523
                     /gene="eno"
                     /locus_tag="IVD26_000945"
     CDS             35225..36523
                     /gene="eno"
                     /locus_tag="IVD26_000945"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAP6078940.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            36922..38061
                     /locus_tag="IVD26_000946"
     CDS             36922..38061
                     /locus_tag="IVD26_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAP6078941.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        12641 a         6673 c         8113 g        10676 t
ORIGIN      
        1 ttaatatttt ttgagtataa ttacgttgtc aggctggatt gtttttttga cagacatgct
       61 ataataactt taattgaata tgaaggggag taccagatga acgaacgaat caaaaacaaa
      121 ttagctttac ttcctgatca gcccggctgt tacttgatga aagataaaaa tggaacgatc
      181 atttatgtcg gcaaagccaa aatattaaaa aatcgtgtcc gctcatattt tactggtagc
      241 cataatacga aaacggaacg gcttgttagt gaaatcgaag actttgaata catcgttaca
      301 gaatcgaata tcgaagcatt gctcttagag atcaatctga taaagaaaaa tgatcctaaa
      361 tacaacatta tgttaaagga tgataaaacc tatcctttcc ttaagataac gaatgaaaaa
      421 tatccccgtt tggtgattac tcgtaaggta ctaaaagaca aagcactgta ttttggacca
      481 tatcccgatg tcggtgcggc gaatgagaca aagaagatcc tcgatcgatt atttcctctg
      541 agaaaatgca aacctagtca gacgaaggag ccttgtcttt actatcattt gggacaatgt
      601 ctgtgtcctt attatttcga cgtagatccg aaagtctata cgaaaatcgt tgatgaagtg
      661 aaaaactttt taaacggagg acacgaaaaa atcgagtcag agatccatca gaaaatggaa
      721 aaagctgctg aaaacatgga gtttgaaaaa gctgcagaat accgagacca gatccgtgcc
      781 attgagacaa tcatgactcg ccaaaaaatg acaaatactg atttactgga tcgagatgta
      841 tttggttatg cgattgataa aggatggatg tgtgtccaag tgtttttcgt aagacaagga
      901 aagctaattg aacgagatgt ttcaatgttt cctttctata acgaagcaga agaagatttc
      961 ttgacttacc tcggtcagtt ttatcaggaa aatgagcatt tcattcctaa agaagtcttg
     1021 attcctgata cgatcgacaa gcccagtgta gaagctttgt tagctacgaa agtgctgcaa
     1081 ccaaaacgag gagaaaagaa aaaattagtt gaattggcga gtaagaatgc ctcagttgct
     1141 ttgaatgaac ggtttgatct gattgccaga aaacaggaac ggacgatcgg agcagttgaa
     1201 cgtttaggaa acgcgatgaa tatcccgacc ccaatacgta tcgagtcttt tgataactct
     1261 aatatcatgg ggacgaatcc tgtggctgcg atggtcgtat tcattgatgg aaaaccggca
     1321 agaaaagaat atcggaaata taaaataaaa acagtcaacg gaccggatga ttatgcatca
     1381 atgagagaag tcatctatcg cagatattcg cgagtgattc gcgaagggtt gcctttacct
     1441 gatttgatct tgatcgatgg aggaaaagga caagtagatg tggcaaaaga tgtcttagaa
     1501 aatcaattag gaatcgatat tcctattgct ggcatggcaa aaaacgataa acataaaaca
     1561 aatgagttgc tattcggtac agatttggct gtagtaccgc ttgagcgaaa ttcaccagag
     1621 tttttcttac tccagcgaat ccaagatgaa gtccatcgat tcgcaatcac tttccatcgg
     1681 cagctacgca gtaaaaacag ttttgcttcc cgattagatg aaattgaagg gttaggacca
     1741 aaacgaaaaa aaatgctgct taaagagttc aaatcgttga aaaatatcac agcagccacg
     1801 acagaagaat tacaagaaat cggactgccg aaaaatgtcg cacaaaacgt atttgataaa
     1861 ttacatcagg aatgaggaaa gggcacttta caaagaaagt aaagtgtcct atcattttat
     1921 gtacaacaaa aagagcgttt acgttttgtt ggtaaataat aaatcgctta cgtctggtgt
     1981 ctaaggatat atgtgatttc ttgaagaagg agtgaagaaa tgttagaagt caaggatctt
     2041 gttaaaactt ttgggaacta cacagctgtc gatcatgtct ctttccaaat ccccgatgga
     2101 aaaatcatgg ggctaattgg ccaaaacggg gctgggaaga caacgacttt tcgtttgatc
     2161 ttggattttt tgacacaaga ccaaggagaa gtgttatgga atggccatca tcttggggag
     2221 aaagattatg atgtcatcgg ttatcttccg gaggaacggg gactttatcc gaaagtaacg
     2281 attcaagacc aactgcttta ttttgcagaa cttagaggga aatcaagaaa agagattgaa
     2341 ccaaaaatcg acttttggat ggaaaaattt caggtaaaag ggaaaaagac ggataaagta
     2401 aaatctttgt ctaaaggaaa tcagcaaaaa gtccagctga tcgccacgtt aatccatgaa
     2461 cctaaattga tcattttgga tgagccattc agcgggttag atccggtaaa tgctgaattg
     2521 ctaaaagatg gaatattgga attgaaaaaa catggttcat gtgtcatttt ttctagccac
     2581 aatatggata atgtagaaaa aatctgcgat catttgatca tgttgcgaaa cggaaaaatg
     2641 gttttgaatg gaaaagtaca tgagattcgt gaatcatttg gccgtacgaa gttattcttg
     2701 gaatctggtt taagccaaca ggaagtagaa gaaatcgaag gcgtgaaaaa agtgatcctt
     2761 catgaagaca atacgttaga gattacctta gaagatcctg aagctgggaa agaaatcttt
     2821 actcgtgcga ctcagttcgg ctacattcct atgtttaacc agcaaccgcc aactttggaa
     2881 gagattttca aattgaaagc aggtgaaatc gatgcgtaag ttttggatta ttaccaaaga
     2941 tgtctattta aaaaatgtta agtcgatttc tttcttgatc atgatattag tcccttttat
     3001 catgctgggt atcatttatg tagcaggaaa ctttgctcaa caaaatagtg atgtcaataa
     3061 aatcggcgta ttggctgata atgagcaaat cagtcagcaa atgagccaag tcaaaacaga
     3121 tgattttgag ttcaaagcag ttgattctga agaaaaagca caaaaagagc tttcggaaga
     3181 aaaaatcgat gcgtatttag tagtctcaac tgagaatgat aagataaatg ggatgcttta
     3241 tagcgaaaat tcattaggac aaagtacaca actactgata caacaacaac tgactggctt
     3301 gcaatcgatg cttcgagcga gtcaattagg catttcacca gaagaagtag ctagcttgag
     3361 ccaacaagca agtttgactc gacaaaaagt caattttgat tcaaaaggaa aaatgacagt
     3421 cggagaagat aactcgacag tccaatacgt cgtaagttat gtagcaacga ttgtcttgtt
     3481 cattattatt ttgacgtatg cgcagatcat tgcacaagag atcgcttctg aaaaaggcac
     3541 gcggatcatg gaagtgatcc tgtccagtac gactgcacaa aagcattttt acggaaaatt
     3601 aacaggtgtt ttacttgttg cattaacgca aatggcatta tacggtatta tttttggtat
     3661 aggatacagt caattcaaag atatggaaat ggtcaaaaat atattagacg gtatctcatt
     3721 ggataacttg attggaccat tcttgtggta ttctcttcta ttcatgatct ttggcatttt
     3781 gattttttct gttttagcag ctttatgtgg ctctttggtc aacaaagcag aagatacagc
     3841 aaaagcaatt ttgccagtga cttatctatc tctaggcgga tacatgcttg gattgatact
     3901 aggagcttca gatccaaaca atatcgttat tcggatcact tcgtatattc cattcttatc
     3961 ttcatatatt atgccggttc gcttagcaaa tgagacagtc ggtatgggtg gagcattgat
     4021 ttccttgttg gtacttgtag ccgtaacatt cttattgatg atcttgtctg caaacatgta
     4081 caaatcgaat gtactcgttt atagcgaagg cggattatgg agttcattga aacaatcgat
     4141 ttcaattatg aggaatgaac gaaaaaaagc ataaaacaat cctaaaatac agaaggaagc
     4201 tggacatcta ttgttcccag cttctttttg tatagaccta ttttatttat tttactatat
     4261 tggatatata ttcattgaaa atagtgtata acaactttat aatattgagt ataccaattt
     4321 ttggaggcgt tttaatggac cgttatttag atttactttc agaaaaattc ccctcaacgg
     4381 aggatgtcat cacggaaatc atcaatctcg aagcaatttt gcagcttcca aaaggaacag
     4441 agttattttt gagtgatata catggcgaat ttcctgcttt tgatcatatt ctgcgtatcg
     4501 gttcaggaaa tcttaaagaa aagatcaaag accttttttc tgaacaaatg acggaaacgg
     4561 atatcagcca attcactatt tttacggctt atccagaata tgcattaacg actgattggt
     4621 acaaagaaca agataaatcg cagctgatcc atcatttgat cgatctttta cggtttacga
     4681 cagtcaaata tacccggtca aaagttcgaa aaggattgcc gaaagaatat agctatatca
     4741 ttgaggaact cttgtatatc gatgaccgta tcaatggaaa aaaagactat gtaaaaaaaa
     4801 tcattgaaca acttgttttg atgaaggaag aagaaaaatt tttaacgaaa cttgcacaga
     4861 cgatccaaaa atctgtcatc gatcatttgc atatcgttgg agatattttt gaccgaggaa
     4921 ctcaagcagc caaagtgatg gatcgaatca tggatttttc ttctgtagat atccaatggg
     4981 gaaatcatga tattttgtgg attggtgcgt attgcggctc tgaggcatgt ttactgacac
     5041 ttttacggat tgcagcacgc tataattatt tatttgaatt agagaaagaa tatgggttga
     5101 atttacgtcc attgttttct tttgctcatc aaacttatca gaagaatcca gtatttgcgc
     5161 ctaaaaacag taaaaatcta tccgaaagag agcaagaaga attagaaaaa atccatcagg
     5221 cactttctat ccttcaattc aaatcagaac atcagttatt ggatcgtcga cctgaattta
     5281 aaatggacga tcgtaaattg ctggaaaaaa tcgactatga agcatcaacg attgatttag
     5341 aaggtcagct ctatgagttg aaaggaactt gttttcaaac gatccagcca gatgatccaa
     5401 aaaaattctt ggaagaggaa caaaaagtga ttgatagttt gatgtattca ttccagcact
     5461 ctttgagaat gcaaaaacat atgacgtttt tgatcgaaaa agggggaatg tatctcacga
     5521 acaatcagca tgtgctgttt catggctgta tacctgtaga cgagaaggga cagctcttag
     5581 catttgaatt agaccaatct tatcgcggaa aagaactgct gggctttttt gaaaaacaga
     5641 taactgaaag cgcaaaagat ctgactgcaa aagaagattt agcaaccgat ttgatttggt
     5701 atgcgtggag tgggccattt tcgcctttat tcggcaagag taaaatggcg acttttgaac
     5761 gttattttct cacagagcct catacgcacg tcgagaaaag caatccttat tatcacttgc
     5821 gagatgaaga gtggttcagt gaaaaaattt tagcagaatt cgacacaaaa gaagaagggt
     5881 cagcaatcat taatgggcac acgccagtaa aagtaaaaaa aggggagtca ccgatcaaag
     5941 caaatggaaa agtatttgtc attgacggag gtttatccaa agcttatcaa aaaacgacag
     6001 gaattgccgg ttattcacta ttatgcaatt cttatggttt ccaaatcgtg acacattatc
     6061 cgtttttgcc tattgaacaa caatttgcaa aaaaatccga ccaaacaaat gtgaaaaaag
     6121 taatcgaaca gcaactacca cgcaaactca atcgtgatac aacaaaaggt atggaactgc
     6181 agcagcagat tacccagctc aaaaggctgt tggactatcg aaaggacgat tgagaagaat
     6241 tccagtgaac attgttccat agactggaga ctgagacaaa agtcgtgtcg cagtctcttt
     6301 ttccggataa acggtgttct tctgccaact cctcggtcac aagtcacact attcaacaaa
     6361 catgaaaagc tgttttttga aattgctcct tgtgactcag agttgaacgg caggctcacg
     6421 acctcttggt ataaacggtg ttcaaaagcc agtttctcgg tattaagcca aatttatgca
     6481 aaaatgtgaa aagccatttt cacaaaattt ttcttaatac tcgaaactaa acagcttttt
     6541 cacaaccccc tcagaaagtc tattaaaatt cattcacaaa gaaatcgaat aagcgctgtt
     6601 cagatggatg tacacggtgg gtaagttccg gatgccattg aacaccgagg attttatgca
     6661 tatcatcttt gctttgaacc gcttcaatga gtccatcgtt agaaaaagcg atggctttta
     6721 ataaaggtga aagatctttg actgcctgat gatggtaaga attcacaaaa tatggatcgg
     6781 ggagaaggtt gcttaacaaa ctgtctgaaa caatcttgac ttcgtgagtc gtaaattgcg
     6841 gggcagtggg ctgttgttca tgttttactg accactttgg atataatgaa agatcttgat
     6901 aaagtgtacc ttccaaaacg acattcaata gttggagtcc ccggcagact gcaaaaattg
     6961 gttttctttg tttcaatgct tccaagatca gtgcctgttc aaattggtct cgttgaatat
     7021 ttgtttccgt tagctttgga tgaggatctt ccatgtaaag ttgtggactg acatcttgac
     7081 cacctgcaag aataagtttg tcgatttgtc caatcagttg aggagctgaa tctggagaca
     7141 tgactggcag aataagaggc aatccttgag catctaaaac tgcatccacg aatccttgcg
     7201 gtgtatagct cacttgattt ccttggaaag tatctgttgc tcgaatcagt tgatttccgg
     7261 caatgccgat gattggtttc atttgtattc cccctaaagt agacttattg taacaaggat
     7321 ttaaaaaaaa ttaaactatg taagacttgc ccctatactt atctgttctt gctgtgttac
     7381 tatctgtaaa gagaaatttc gtgtgaaatt catgacgata gttgaaaata ttgcttaatt
     7441 tgttataata aaaagtaagc agaaataaaa aggttgggcg taagcttcaa ggatctagtt
     7501 cttcaagggg tgagaaggac attttattga aggggcctgc ctatactaag ttatctttag
     7561 aggtacatac tttcaatgaa aaaagaaagc atgtacctct tttttaaatc gaaaggaagt
     7621 gaagcaagtg ttagaagctt tggaacaaat ccgaaaagca gaagaagaaa atgaaaagcg
     7681 tgctcaaaca ctgcggcagc agctgaagat ctatgcaaca gaaaaagagc aggaattgga
     7741 aacgatccaa acaaactatc gacaacaact aaaacagttg gtggaagaaa aagaacaatt
     7801 tgaaatacaa gaattagaaa aagaaaaaat gaaattgaaa gcagaagcag acaaggtgca
     7861 agcaactttg aaagatcaat atcaaaagca tcagagtcaa gcgatcggtg cgatcattga
     7921 aagggtgaaa gaaacttatg gccgtcacta agatggaaaa agtgaccctc atttcagata
     7981 aaagaaatca ggagaggatt ttacaagcag tacaaggaat ccaaaacgtt gaaatccggg
     8041 atctgtatca aaatagaaca aacaaccagt gggtggagaa gtattttcca gataccacga
     8101 ttattgataa agaagcaaaa ttaagcgctt taggtaatcg gttgaaagac atccaagaag
     8161 ctatccaatt catacaacac cacggcgata gccgtcaaaa gaaactccat ttgaaacgtc
     8221 aagaactttc cttacaagat ttggaagcca attattccga agaaaatttc ataaataaat
     8281 tgaaagaagt ccttgattta aaagaaaagt gggaacaact aactgaagaa cgtgatcgtt
     8341 tagaagaaga ggaagaatgg cttcttcatt ggcaacagct ggatattgct ccaagtatgt
     8401 atgcaagtaa gacgaccatt tttgagatgg ggactgtgag tgcagcaaat tttgaaagtt
     8461 tcaaggaaga actgagtaag cttgatgacg tttatatgga agaaatagat tatacgccaa
     8521 aacaagttta tctttcgtat gttgctttaa aaaaatcagt tgctgttata gaagaaattg
     8581 ctgggaaata cgggttcaat aaagaaacgt atccttatga acaaaatcct aaagaaaaac
     8641 tgcaagagac caagcagcaa ttatccattg ttcacgagca gcaaaagaag ataacgacag
     8701 cgttaggtca gtgcagtggc tatatccaag aatttgaatg ggtagaagaa gtcacacttg
     8761 ccgttgcaga acgagaaaaa ataaaagaac ggtttatcca tgcgacttat ctgatcgttt
     8821 tgcaaggttg ggtagatgca gaagaaaaac agaatttgct gcatgtgtta aacgaaaccg
     8881 tatcagaaga agatatatac gtcagtttcg aaacaccaaa ctcagaagag attcagcagg
     8941 aagtccctac taaattgaaa aaccatccgc ttgtcgaacc ttttgaattg ctgactgaaa
     9001 tgtacagtct gccaaaatat gaagaagtag atccaacacc ttggatgaca ccattttatc
     9061 ttgtcttctt cgggatgatg gtcgcagatg ttggttatgg tttgctgatg ctcattggga
     9121 caatactagc tcaaaaacta cttgttctac cacgcgggat gaaacgtttc gtaaaattct
     9181 ttgagattct ctcgatacca tcgatcatct ggggattgat ctacagttca tttttcggac
     9241 agtcattacc aaaagaactg tttggcatcc gcttgccttt cccaatccta tctacgacgg
     9301 atgacgtcaa tacgattttg attttatccg tgattttcgg tctgatacag attttggttg
     9361 gattatttgt ggcagcaaag gaaaatatca ggagaaaaga ttacttgagt gctgtcagtg
     9421 atggatttgc ctggcaaggg atcctaattg ggatcgttat tgcgttggtt ggtgccatgt
     9481 tgataaaaaa tacagcattt gtttaccttg gcgctgggct atcgatcatt gctgccttat
     9541 gtatcttgat cgttccgatt atccaaacgc cgtctaaagt caaaggtgct gccaaaggtg
     9601 cgtataatct ttacggactg accggctata tcggtgattt agtcagttat acacgtttga
     9661 tggcattggg tatttcaggc ggaagtattg gagcggcatt caatatgcta gttgctttca
     9721 tgccgccagc tgctcgattc agtgtaggga tccttttgat catcgcttta cacgcactga
     9781 atatgttttt gacactgcta agtgcctatg tccatggcgc acgattgcag tatgtcgaat
     9841 tttttgggaa gttttataca ggaggcggac gtgcctttga tccgctgaaa acggcggaaa
     9901 aatacgtcaa catcaatcac aagaaaaaaa acaataaata attggaggat ttttatataa
     9961 tgatggatta cttaattagt caaaatggtg gaatggtatt tgcggtatta gcgatggcaa
    10021 cagcgacgat tttttcaggg atcggttcag ctaaaggtgt tggaatgaca ggtgaggcag
    10081 cagcagcatt gacaacaagt caacccgaaa aattcgggca ggctctgatt ctgcaattgc
    10141 ttccaggtac gcaaggtttg tatggattcg ttattgcctt tttgattttt atcaacttag
    10201 gaaatgacat gtcagttgta caaggactga actttctagg tgcttctctg ccgattgctt
    10261 ttacaggctt gttttcaggt attgcccaag gaaaagtcgc agcggcaggt attcaaattt
    10321 tagcgaaaaa acctgaacat gctacaaaag gaatcatttt tgctgcgatg gttgaaacat
    10381 acgcgatttt aggtttcgtt atttccttcc tattagtgtt gaatgcctaa gcataaagga
    10441 ggaaaagcag atgaacgcca ttgaaaaaat catctctcag atgaacgaag cagcagagca
    10501 ggaaagagcg gcgttagaac aagaagagcg aatgaagatc gatcaaaact ttgaacaaaa
    10561 acgtacgcaa gttgaaacag aacatcaaaa acaaaaagaa aaacaaatcg aattactcga
    10621 aaaaaaatac cgtcagctaa ggaatcgcca gcaagtagaa gtacgacaag aaaatttgaa
    10681 tgcgaagcag gaatttttaa gacgattgtt tgcagatgcg gtaactgaaa tggaaaattg
    10741 ggatgaatct gaacaaatcc agtttatcaa aaatgcattg tattcattac ctttgacagg
    10801 aaaagtagca ttcattgctg gagaaaaatc agcagcctat ctttctcaga cgttgttgga
    10861 tgaatggaac aatgaacttc cctttatgat ggttttaagt gatgaaactg ttgctgatca
    10921 agcgggtttt ctgataaacg atcaaggagt tcagtataat tttcttttca gcagccttgt
    10981 acaagatatc caaggaacga tgagttttga gattgccaat caattattcg aataaggagg
    11041 gatcagtgta tggaatacca cgaactaaat cccttgattc gcggaagaga gcttgaactt
    11101 ttgtccaatg agacatttga acggatgatt caaacaaatt ctgtcgaagc acttggtgaa
    11161 atattgaaat ccacgattta cagtccatat atttatgacg gatatgaata tgacttcgaa
    11221 cagaatcttt taaaggagca gagccgtcta tttcgctggt taaaggaatc agcaccggag
    11281 cctgaaatcg tttggatcta tacgatgcgt tatactttcc ataatctgaa ggttttgaca
    11341 aaagctgaga tgacaaatca aaatctggac catttgtata tcgacgatgg attttattca
    11401 ttagaaacct tgaaggatgc cattcatacg caagtttcaa atgaacttcc tgaaagcatt
    11461 atggacagta tacgagaagt acgtgattat tttgaagagt ctaccattct tcagggaatt
    11521 gacgtgattt atgatcgaca gtttttgaca gagcagcgac ggcttgccga taagctagga
    11581 tatcaagaat tgctgacaga agtcattgct tttattgact tgaccaatat cacaacgatg
    11641 gctcgaggaa tattgcagaa aagaacatat gggttcatga cgacggtact ttccagctcg
    11701 ggaagtatcg aaaaagaagt atttttgaac tttgtagata aagatatgga agattacacg
    11761 aattttctat tagagacaga ttatgctgat tttctgcgcc ctgtcatccg tgagggaaat
    11821 attgatctcg taaagcttga acagttgaaa gatgattatc taagttcatt gtatcaagaa
    11881 gcacaaaccc aggctttcgg accactgcca ctactagcct ttttgaacgc aaaagaggta
    11941 gaaagcaaaa accttcgttt actggttatc ggcaaaagaa gccatttcga atcagaaaca
    12001 atcagaaagc gggtgagaca agtctatgac gcataagatc ggtgtagttg gcgacaaaga
    12061 ttctgttttg ccattcaaat tgtttggctt tgatgttcgt tatggtacaa ccaagcaaac
    12121 cgttcgtcag gcaattgaag aaatggcaaa gaatgagtat ggcgtgattt atgtcacaga
    12181 gcaatgtgca gcattgagcc cagaaacgat cgaacgttac aaggaacaaa tgatacctgc
    12241 tatcgtattg attcccaatc atcaaggatc attagggata gggctggaag aaattcaaaa
    12301 aaacgtagaa aaagcagtag gtcaaaatat cttatagtat gaaaaggaga tagaaatttt
    12361 gcaaattgga aaaatcataa aagtctccgg acctcttgta atggctgaga acatgtctga
    12421 tgccagtatc caagacatgt gtctagtggg agatctagga gttatcggag aaattatcga
    12481 gatgcgtggc gatgtggcgt ctattcaagt atatgaagag acttctggaa ttggtccagg
    12541 cgaaccggtt cgctctactg gtgaagcttt atctgttgaa ttaggaccag ggatcatttc
    12601 acaaatgttt gacggaatcc aacggccatt agataccttt atggaaatca cacaaagtaa
    12661 tttcttaggg cgcggagttc aattgcccgc attggaccat gagaaaaaat ggtggttcga
    12721 accaacagta gaagccggag aaacggtgag tgctggagat gttatcggga tcgtagaaga
    12781 aacaaaagtt ataaaacata aaatcatggt gccaaatggg ataaaaggaa cgatcaaaac
    12841 aatcgaaaaa ggttcattca ctattgatga aacagtatgt gtcattgaaa ccgaaaatgg
    12901 tgacaaaaat ttgacgatgc ttcaaaaatg gccagtaaga cgtagtcggc caatcaaaga
    12961 aaaattaaac ccggatgcac ccatgatcac tggacagcga gtgattgata cattcttccc
    13021 agtgacaaaa ggaggagcag cagctgtacc tggtcctttt ggtgcaggga aaacagtcgt
    13081 tcagcatcaa attgcaaaat gggccgatgt ggacatggtt gtctatgtgg gatgtggcga
    13141 gcgtggaaat gagatgacgg atgttttaaa tgaattccct gaattgattg accctaatac
    13201 aggagaatcg ttgatggaac gtacggtatt gattgctaat acatcaaaca tgccagtagc
    13261 agctcgagaa gcttctatct atacgggaat cacaattgcg gaatatttcc gtgacatggg
    13321 ttatgacgtt gctatcatgg cagactccac ttcacgatgg gcagaagcac ttcgtgagat
    13381 gagcggacgt ttggaagaaa tgcctggtga tgaaggttat ccagcttatc ttggttcacg
    13441 gcttgcggaa tactatgaac gatctggaag agtcattgca ttaggatcag aaggtcgcga
    13501 aggaagtata accgcaatca gtgctgtatc cccgtctgga ggggatattt cggaaccagt
    13561 cacacaaaat acattgcggg tcgtaaaagt attctggggt cttgattcca gtttagccca
    13621 aaaaagacat tttccttcga tcgattggat acaaagctat tctctttatt caacagaagt
    13681 agggaagtat atggatcata tccttcaagc tgactgggca tccatggtca ccgagggcat
    13741 gcgtattttg caggaagaac agcagctgaa tgaaatcgtg cgtttggtag ggattgattc
    13801 cctttcagat aatgaccgtc tgacattaga agtggcaaaa tccattcgtg aagattattt
    13861 gcagcaaaat gcttttgatg atgtcgatac attcacttca agagagaaac aattcaaaat
    13921 gttgaagatg atcttgacct ttggtgaaga aggacgccgt gcgttgtcgt taggtgctta
    13981 tttaagtgag atcatggacg gtaccgtatc gattcgtgaa aggatcggac gaagcaaata
    14041 tatcccggaa acagaattag aaaaactaga tcaaattatt ggtgaaatca agcaaacgat
    14101 gcaaacgatc gtttcagaag gaggcatgag caatgattaa agaatatcgt acgatcggtg
    14161 aagtcgtcgg tccattgatg gcggttgaaa aagttgctgg tgtcaaatat gaagaattaa
    14221 tcgaagtccg tatgcaaaat ggcgagattc gtcgtggaca agtattggaa gtccaagaag
    14281 ataaagcaat ggtccaaata ttcgaaggaa caagtggtat caatttacgt gactcttctg
    14341 tacgattttt aggccatcct ttagaactag gtgtatcgga agacatgatc ggtcgagtat
    14401 tcgatggttt gggacgaccg aaagataacg gaccagagat cctgcctgaa aagcatttgg
    14461 atattaacgg agaagtaatc aatccagtag ctcgggatta tccagatgag tttatccaaa
    14521 caggtatctc tgcaatcgat catttgaata cattagttcg tgggcaaaaa ttaccagtat
    14581 tttctggctc tggtcttcct cataaagaat tagctgctca gatcgcgcga caagcaacgg
    14641 tactcgattc atcagatgat ttcgccgtag tctttgctgc tattggaatc acttttgaag
    14701 aagctgaatt tttcatggaa gattttcgtc aaacgggcgc aatcgaccgt tctgtcatgt
    14761 ttatgaattt agcaaacgac cctgcaatcg aacgtatcgc tactcctcgt atggctttga
    14821 ctgctgcaga atatcttgct tatgaaaagg gaatgcatgt tttggttatc atgacagaca
    14881 tgaccaacta tgcagaggca ttgcgagaga tttctgcagc acggcgagaa gttccaggaa
    14941 gaagaggata tcctgggtat ctttacacga acttagctac tttattcgaa cgagcaggaa
    15001 gaatccgcgg actaaaagga tcggttactc aaattccgat tctaacaatg ccagaagacg
    15061 ataaaactca tccaatccct gacttgactg gttatattac agaaggacag atcatcttga
    15121 ctagagagct ttacaagagt gggattcagc caccaattga tgtactcccg tctctttcgc
    15181 ggttaaaaga taagggaact ggacccggaa agacaagaga agaccatgca gctacgatga
    15241 atcagctttt tgcagcctat gcacaaggaa aacaggcaaa agaattagcc gtagttttag
    15301 gtgaatctgc tttatctgat gtagacaaga tctatgcgaa gtttgctgag cggtttgaaa
    15361 aagaatatgt caatcaagga ttctacacga accgttcgat tactgaaaca cttgatctag
    15421 ggtgggaact gctatcgatg ttgccaagaa ccgaattaaa acgaatcaaa gacgacatgc
    15481 tggacaaata tctgccagaa gggaagtgag ttctgatggc acgattgaat gtgaatccga
    15541 cccgcatgga attgactcga ttgaaaaaac agttgacaac tgccacaaga gggcataaat
    15601 tattaaaaga taagcaagat gaactgatgc gtcaattcat cctgttgatt cgaaagaaca
    15661 accagctgcg tcaagaaatg gaagagtcta tgacagaagc aatgtctgat tttgtattgg
    15721 caaatgcttc gatcacggaa cctttcatcg aagaattatt tgttttgccg gcggaaaacg
    15781 ttgatttgtc tatcgtagac aaaaatatca tgagtgtaaa agtacctgtg atgaattttg
    15841 aatatgatga acagctgaca gacacacctt tggaatacgg gtatttgaat tccagtgccg
    15901 aactggatcg gtcaatcgat cggtttacta ccctgcttcc aaaacttttg gaactgacag
    15961 aaatcgaaaa aacttgtcaa ctgatggcga gtgaaatcga aaagacacgt cggcgagtca
    16021 atgcattaga atatatgacg atccctcaat tagaagaaac gatctattat attcgtatga
    16081 agctggaaga aaacgagcgc gcagaagtaa caaggttgat caaagtaaaa aatatgggta
    16141 ccactgacta agtggtatct ttttttaaaa gaggaaaacg atgattaaac aaagcaaaca
    16201 aataaagaaa cgtttgccgg ctgttcagct tctcgcatta ggattttttc tcctgatttt
    16261 agttggcggc ggcctactta ccctaccatt ttttagtaat agtgggcatg ggacaaattt
    16321 tatcgatgcg cttttcactg caacttctgc tgtctgtgta acgggattga caacattgaa
    16381 tacagcagag cattggaaca gtgctggtca atttttgatc atgcttttga ttgagatcgg
    16441 cggtcttggt tttatgatgg ttccgattct atgctttgca ttgataaaga agaaagtcag
    16501 tctcagcaca cgtattatat taaaagaagc gctgaatcta gaagaagtat caggtgtgat
    16561 gaagctcatg ctttacatcc taaaattggc ctttgtgatc caattgattg gtacggttgc
    16621 tttatctttt gtatttgtgc ctgaatttgg ctggttgaaa ggtatctggt acagtttgtt
    16681 ccatgcaatc tctagttttt gtaatgcagg gtttgatttg ttaggagaca gtttagccaa
    16741 tcaccagcaa aatgtttatt tgatcatggt ggtatctgct ttgatcattt ctggtgggtt
    16801 aggcttcatc gtatggcgtg atttactgga atatcatcag aaaaagaaga tgacgattca
    16861 ttcaaaaatc gcattaaccg ttacaggtac ccttttatta ggcggattcg ttgtgttctt
    16921 tttcacagag cgcaatgggg caacgctagt ggaagggaat atgtttcaac gattggcaaa
    16981 cacctttttt atgagtgtga cacctagaac ggctggatat tattcagttg attacctcca
    17041 tatgagccat gcaggtctga ttttaacgat gtttttgatg tacatcggcg gaacatctgg
    17101 gtcgacggcc ggcggattga aaacaactac gttaggtgtg ttgctgatcc agatgcgttc
    17161 gatgttgaaa ggacgtacga gagcggaagc atttggccgt accatccgac aaggcgcagt
    17221 gttgcgggca cttactttat tttttgttac gttgacgttg tgtgtagtcg ccatcatgat
    17281 tttatcggtg actgaaacga tacctaaaac ttctggcatc gaatatattg cttttgaggt
    17341 cttctctgcg tttggtacag taggtcttac gatgggattg acgccagact tgactgcaat
    17401 agggaaattg atcattatag cgcttatgta cattggacga gttggtgtat tgactgtggt
    17461 cttctctctg atgacaaaag cacaaagaac acaatcaaaa tacaaatatc cagaagaaag
    17521 tgtcatgatt ggataatttc atcttctgac agaaacctag tgatttagta aaataagaaa
    17581 ataaaataat ttttcttgct tcttggatac tttaagtgca aaatgttcgt ttattttttg
    17641 aggcactacc cgttgttgaa cctcgggtag tgcctctttt ttattgaaag gaatcaataa
    17701 gatttgattc ctttatttat caataggtta taattcatat ttttttattt tttcttttac
    17761 gatacttagt ccagaagcta aaatttcaag gttattagag gatagggaaa ttcgaacgaa
    17821 tgcatctggt tgcgtacgtg tagtaaagcg tctggaatga taaagtcgga taccgttagc
    17881 aagaaagtca ttctcaatta tcttagggtc aatctcagga tcaactggaa gaattcgata
    17941 gtaagggaca cgattcgttg gtttttctac tttgaaaaga gaatcaaaaa gctgattggc
    18001 tctttttgta agacttaatt tagtttctaa gatcctattt gcttcatttg aatggaggat
    18061 ttgagtgatg acttccacat ctaatccaga agttttcaca tttatattaa aaattgcttg
    18121 ttctatcttg ctttggacat gtactggaac tacaagataa gcaactcgca atccagaaca
    18181 aataaatttt gtcattccag ctaagtagat tgtttggtta ggtaataaat tttggaaagg
    18241 aggaatgatc gtatgttgat agtaagttgt taaaaatgaa tggatatcat cttcaataac
    18301 ccatagacct tctttttcaa tcacttcggc taattgctct cgtcttttgt gagagatttg
    18361 aaaccctata ggattattac aagaaggcat aagaaagaca ccatgaatct tcttttttct
    18421 acattcctga atcaatatat caggtcgcat tccttgctcg tcaaaatcaa ttggaacgat
    18481 ctctaaatga tataactgag ccaattcaat gaaattagcg tatgtatatc ggtctgttgc
    18541 tattctatca cctggagaga aaagtgcaga aagtgtgata gccaatccat tttgaacacc
    18601 ggaaacaata gatagagatt ctaaggacgg aatgactcct tgagttttta accaatttgc
    18661 tgcagtagtc aattgaaaat ttgtgccttt gggatcttgg taattaagca aaccaacaag
    18721 atttgggtta ttactagttg attgaataaa cgggacaacg aatttattac attcttcaaa
    18781 agaactaacc agaccaaaat caatgatatg ttcggttact tcattggtag agatggtgat
    18841 ggactcaaag acattgggag aaataaatgt gccacttcca atattcgtat acagcaaacc
    18901 tttctcaatt ccatatttat aagccttgcc aacggtagta aaatttaaat ctaaataatc
    18961 agctagctct ctttgggagg gtaactgagt gtttttctgt aatttattct ttaaaatatc
    19021 ttgttctaat tgttgaatca acgatcgata ataaggacgc ttcaattttt gtttgtctgg
    19081 tcgccaagtt aacgggtaat tgtcataaga attaataggc attttctcca ctccttaaaa
    19141 ttgtatacca tacaatttta ccattgattg tattgatttt agaagttaat cttttgtgag
    19201 gagggaattg tctatgaaaa ttattaattt tgaggaagta gtagcttctt ttagttttga
    19261 agaagcgatt caagtaatga aaaaatgttt ttttgattat gaaagtggta aaatcagcca
    19321 aaatcctcga ttggtggaaa ttttacctga cggaaaaggc aaaaatatgt ttgcgatgat
    19381 gcctgcttat ttgggggaga acagatattt tggcacaaaa gtcattaccg cttttccgga
    19441 taatcatcag tatcatttac cttctcattt aggagagatt ttcttgtttg atgctcaaaa
    19501 cggactaccc aaagcattga taaacgcaaa tgcagtcacc tggattcgaa cagctgctgt
    19561 atctgcgctg gcaacagatt acttagcaaa tccgcatgca gaaacacttg ctttaattgg
    19621 agctggtcaa caagcattgt cgcatttgac tgcgatttct accattcgtc ccatcactac
    19681 agtgtttgtt tacgatattt tagaagaaag acgaaatact tttatcgcta aagctaaaaa
    19741 acagtatcct aaaataacgt ttataaatgc aatatcagta gaagatgcag tacgtccagc
    19801 ggaaatcatt tgtacgttga cctctagtaa agaggcattt cttcaaaaag agtgggtaag
    19861 ggaagacgca catatcaatg ctgtgggcac atttactcct gatacaagag agataagtac
    19921 atcgttgatg gaaacttctc aaatctatgt agatgattac tcagctgcct taacagaaag
    19981 cggggacctg cttatagcca tggcagaagg agatttagag gaatcttgta ttgttggtac
    20041 attaggcgaa ttagtttctg agaaaaaaac attttataaa ggagaatcga ggccgacgat
    20101 tttcgacgca gttggtctag ctattgaaga tctttgttgt gcagaatata tttataacaa
    20161 attagagaaa ggggctttaa aatgaactta gattattacg tagttgatgc atttgcagat
    20221 gaggtgttca aaggaaatcc agcagcggtt tatgtgctag aagaatggct gccagaaggt
    20281 acgatgcaaa aaattgccat tgaaaacaat ttatctgaaa cagcatttac agtgaagaaa
    20341 aaccaagaat ttgagcttag atggtttacg ccagatcgag aaatcgatct ttgtggtcac
    20401 gcgacattag caacagcatt tgttttattt aactattaca aaatacctga tgaaacgatt
    20461 aaattttcta ctcaaagcgg taatctattt gtgacaagaa ttaaagatta ttattacatg
    20521 gattttccta gtattatgcc gaaaaaagtg ccgatattgt ctgaatatga agaagcgatt
    20581 ggggctaaga ttaaagaagc ctacttagca cgtgatttat ttttcgtatt agaagatgaa
    20641 aaaacggtgg ctaaattgca gccagatttt acagctatca aaaattttga attaggaata
    20701 ggagtcatcg tgacagcaga aagtgtgcaa aaagactttg tttctagaac cttctttcca
    20761 aaattaacaa tcaatgaaga tccagtatgt ggatcagcac attctaatct tattccttat
    20821 tgggcagaaa gaatgaataa aacaaaattg tcagcttatc aaatgtcatc aaggggcggg
    20881 gatctagaat gtgaattaaa agaagatcgt gtgataatag gaggaaaagc agttttgttt
    20941 tctaaaggta cctcgtttat ttgatttctt tcaaatgaat taaaaataaa ttggtggaga
    21001 gtggcaacct tatagctaca atggttgtta aaaaaagacg caaacttttt caatttaatg
    21061 aaaagtttgc gtctcatttt aattattggt gtttgttttt tattcaatca agagtaaaat
    21121 gccccatact aactatcctc ggatgacttc gattttataa ccatcagggt caatgacaaa
    21181 gtagtaagaa ggcgcagtgc caggtaatcc ttttaagtca gtaatctcaa gaccagcagc
    21241 tttatgttgc tcgtgtaatt tttctagatc atcagctgct atagcgatat gaccatagcc
    21301 gtctcctaga tcatacgcac catgatcata gttgtaagtc aactctaatt catagtcatc
    21361 cccaggaagt gtcaaataaa caagtgtaaa tttgttttct ggaaaatcac ggcggcggct
    21421 ttcttcaaaa ccaaatgcct tttgataaaa ttcgattgat gcttcaagat ctttcactcg
    21481 aacacatgtg tgagccattt tcatagattc atctctcctt ttccttttac tcaatcataa
    21541 caaaaagaag taaggaaata gttgatttgt gcttgttcat gagaaatttc tcatgtaaaa
    21601 tggatagaaa ataaaactgt taaggtggaa actattcatg gataaaccaa tttttggtga
    21661 aaaaaagcaa tttgctgatt atcaaacccg ttatgcagca tatattgtca tagaaagaga
    21721 tcagcagatt gcagtaatcg aggctccaaa tggtgctttt tttcttcctg gcggggaaat
    21781 tgaaggagaa gagacgaaag aagaagcgat tgtccgtgag ctgatagaag aaatgggaat
    21841 tgtggcagaa atttcttctt atctgggaga agctgatgag tatttttact cgaattatcg
    21901 tgcaacttat tattataatc caggatattt ctttgttgct gattcttgga agcgtatagg
    21961 agaaccaact gaaaagacca ataaaatttg gtgggtgagc cctcaagaag cgcttgtgaa
    22021 attgaaacgt ggtagccacc gatgggcagt cgagagatgg atcgaaaaaa ataaaaactg
    22081 aaagaaagcg agtagatcag ctttctctca gtttttttat ttattacagt acatattttt
    22141 tgattgcttc agctacaccg tgctcgtcgt ttgatgaagt gatgacattt gctgcttctt
    22201 tgacaagaga aacggcattt cccattgcta ctcctagacc agcatattca atcatggata
    22261 agtcgttctc gttatctccg atagccatga tttcatcttg atcaatacca aggtgctgtg
    22321 cgagattcgc aactgccgca cctttacttg cttctttatt tagtacttcg aagtaatagg
    22381 gcgcactttt gaccgttgtg tatttatcac ggaaagtttg cggtaaacgc gcaattgctg
    22441 catctaaaat ttctggttcg tcgatcatca tcattttgac gatgttcatg tctggtgtca
    22501 tttcttcagg tgttcgatat tttagcggca tcttgactaa acttgcttcg tggatcgtat
    22561 aagcgctgat atctcgatta ggcgtgtaga tcgctttgtc atcgatcgaa tggagatgac
    22621 tgccgacacg gcgtgccatc acttcgatct ctaggaaatc ttcatgtgtc agtccgtgac
    22681 gggcgatgat tttacctgat ttcgtttgtt gtacgagtgc cccgttataa gtaataacgt
    22741 aatcattatc ttgaaaaagg ttcaactcgt ttaactgttc ctggacacct ggtaagggac
    22801 ggccagtgca taaaacgatc gaaacacctt ttgcaacagc agcggcaatc gcttctttta
    22861 cttcttttgt tacttctctt ttctcattta ataaagtacc atcgatgtcg atagcgacta
    22921 gtttgataga cataatttcc tccaatatat tttaatttat ttcaatcaat gcgccattac
    22981 ggatatggct ggcaaattct tgataagttt cgtcaaataa atcataatga tcacgcaagg
    23041 acggatcaac catttctttt ggaaagaaaa atcgctcatc tccttgttct tgtcccgcta
    23101 atgcagcaac aagctgacta acctgtgata attctatcaa agttccgtca tttcgcaaaa
    23161 tctcgatttg tgtgcgatgt ctgccttgtt ctgggcgata aaaatcataa ggtagatcgt
    23221 agctagaatt cacagcagtg taataaacag gattatatcc gaccttttct actaacaaag
    23281 tgagttcttg gactaatttt gaatcccggt tgccagaaaa agtagcagat ttcagtggtt
    23341 tacgattcaa aaaacgttta gctaaatcat ttaaaatagg atcagcagat tcagaccatt
    23401 gagtaaagta agtgcccaag accccatcat caagtttgag gtattcttct aaagtaaagc
    23461 ttccgtcaag aaatggcaga agtaattgag aatggagttc aaaactgctg gcatcttctt
    23521 gatacaactc gtgtgcgcga tgaagcagat gctccaaaat tacttccata ccacgggaaa
    23581 caggatggaa gtacacttgc acatacattt gatatcggct aacgatataa tcttccactg
    23641 catgcatgcc actcatggaa aaagcgatcc cgccttcata aggacgaatc acacgtaata
    23701 ttcgggtaag atcaaatgtt ccatattctg ttccagtgaa ataagcatcc cgaagcaaat
    23761 agtccattcg atctgcatcg atctgactag aaatcatttg gacaacttgt gggttggggt
    23821 aagttttttg gatcacacta gctacctttt caggaaaacc ttcttctact cggttaagaa
    23881 tctgatacac ttctgtttct ggagaagtga tgatctctac agtgatggct tcatgattcg
    23941 tatggaagat atgttcaaat gtatgagagt aaggaccatg accgacatca tgcaacagtg
    24001 ccgcacataa agtcaccagc cgttcctgat catcccagcc tccgttgcct attttttctt
    24061 ttgaaaaatt tcgagaaaag atatcgcaga ttcgtcttga aatctcataa acgcctaatg
    24121 aatgagtaaa acggctatgt tctgctccgt gaaaagtgaa agaagaagtg cctaattgtt
    24181 taatgcgtcg tagacgttgg acttctttcg aattgatcaa atcgaagatt acttgatgct
    24241 ggacatggat atagttatgg actggatcac gaaaaacttt ttccataggc agcatttgat
    24301 atttataagg ggttgtcata atgtagctcc tttatgttat tacgttgttc cattctctgg
    24361 atttggttgt tccattgctc cagctggatt tcttttttta gccagtcggt agaatcctgt
    24421 aaatcacttg cagaatacag cttttcaaaa gcttttgcaa atgcttcttt gacttctttt
    24481 acaaaaaggg gttggtcaag cagttcttca agtgttgcca ttgtagcagg atccactgca
    24541 ggatagccat ttgtaccaaa gtcttctttt aaagcagatt gataaaatcg cttcatgact
    24601 tgcccgcgtt tttcctgatt accgttgaca cttaagtaca tcataacaga aatcccattt
    24661 ttgatccgac gctgagcgat accggcaaat tttttgccat ggatgcttaa atcataagtt
    24721 ccaggacaat aagaatgggt gatttcgaat gcttgtatcg gtgcctttgg aaaagcgtat
    24781 ttagtcaata ggagcatttg ctcgtaagcg tcatctatgg ttattttttt tgtgtcactt
    24841 tgggggaaaa tcaaagaaat attcaaaatt ccttcatctg atacgatccc taatccacct
    24901 gaatttctga tcactggagc gtaacctgca tctttcagtg tttggatccc gtcacttaga
    24961 aaaggagttc gaacatcctt catacctaag atgactgtgc agtcatattg ccagaaatgt
    25021 aaaaagattt gctggtgttc tttagaatat tccgttaata tatctgttaa tgcaaaaggg
    25081 gaaaagtcgt ttttttgata aatgtgctga tctagtcgaa tcgcagggtt cattcaaccg
    25141 gctcctttgt ataaattcat attttctaca atattatact ctaaaatcaa agagttgttt
    25201 tggaaaaaag gttttctgta aaaatggaca agttggttga caaaacaaaa gaaactagga
    25261 acaatgtagc tatgagaagt aaaggagaat gaataatgga attatcacaa ggaacaccga
    25321 tttcaatcaa attgcgtaca aaagtaaaac agcaagggga agtgcaagat ttttattttg
    25381 atttgaaagg gcaaatggtg acaattggcg atacgctgta catacgttat aaagagattc
    25441 aggaggagac gggcgatgag attcctgtaa cgatcaaatt agttccagat ggtcatgtac
    25501 agctgatccg tgcaggagaa atgcggatgc gtttgaaatt tggctataaa gaacggttag
    25561 aaacatccta tcgaacacca tacggtatga tccagattgc tacttttacg aaagaactgc
    25621 atgttagttt gaaagaccgt cccacagcag ggaaggttcg aatcgattat gatctgttca
    25681 tgggaccgga aaaaatcggc gaatattatt tgaccttgga ttttacagcg taaatataaa
    25741 agaaaagttt gattttttgt gtctgatttt gtatgataag gagtagactg tgaaaggacg
    25801 tgtcctgatt ggaaattagt gtatttgaag gtgcaaacaa aagcgaatta tcaatgatcg
    25861 aagtagcaca cgcgatctta gaacaacgtg gcgatgtcat ggatttttct gatttagcta
    25921 accagatcca aaactatctt gggaaatcag acagtgaaat tcgtgattca ctcgcacaat
    25981 tttatactga cttgaatatt gacggcagct ttatctcatt aggggataat cgttggggct
    26041 tgcgttcatg gtatgctatc gattcgatcg atgaagaagt aaaccatgga atggacgaag
    26101 aggatgaaga tactccacgt cgccgtaaac gcaagaaagt caacgccttt atcaatgatg
    26161 atgaagacgc gatcgattac aatgacgatg acccagaaga tacagatctg acagaagaag
    26221 atgacgatga tctgtttgat gacgatgatg atgaagatga agaaatcgct gcttataatt
    26281 ctgacttgca agaaatcgga gcagatgacc cgacagatga tgaagaagac ttgccaggaa
    26341 atatcgaaga agatttaagt atcatagacg aagacgatga tgatgaagat tatgaagagg
    26401 aagaattttc tgactctgaa aaagaataaa cattattttc ttacgagagg ttgtgacaga
    26461 gacgatcagc ctatcagaat aaggaggtgt gacacgattt ttgtcacacc ttcttttttg
    26521 tatataaaaa tcccaagtaa atacataaaa aataaaaaaa ttgaaacttt tagcgcacct
    26581 tgtacgtcat attaagtgag gcagaaagga gtggagaatg atttttactg gatataagaa
    26641 aaaacggcag atcgaaaaat accgtcacct gctgaatgga ctcatcgaaa ctgattatca
    26701 aaaaatgttc cgtatcacga tgaattacgt acatgataaa gaagaggcct tagatgtgat
    26761 gcaagatagt tttcataaag ccctgaacta ttttgaaaaa gaaaaagaga tcgagcattt
    26821 tagtgcatgg ttttatcgga tattgatccg cacggcatta gatagttggc gcagacaaaa
    26881 aaggacgcct gtggacttat ttgaaattca agatatcccc caacagttac ctttagaaac
    26941 ttccgttgca gagctccata tgattttaga taaaatagac agtccggaaa aagagattct
    27001 gatcctctac ttttttgaag gatttcgttt gaaagaaatt gcgactatct tggatatgaa
    27061 tgaaaacaca gttaaaacga aaatgtaccg ctcattgaat gctttacgtc aaatcctaga
    27121 atgaaggaga gaagagtgcc atgtattccc aaaaagaaaa tttaaaaaaa ctaaagaaaa
    27181 cttataaaga acaagcaatt cccaaagggc ttaaagagga gatccgccag cgttttatta
    27241 tcgaagagca atcatttata aaagcaaagc ggagaaagag acgtctccaa gggttcggag
    27301 tatctttggc tatcgtaatg attacaacaa gtagccttct ttttaatagt caagttcgaa
    27361 gctttgcaga agatttaccc atcttaggat cagtcattga attgatctta ggcgaacgct
    27421 ttactgatcg atctgaaaaa atcgatattc aggtaccgaa gatcaataca caaaatgaga
    27481 aagaaaataa aacaattcat ggattaaatc aaaaatactt tcgcgaagga caagcagatt
    27541 ttgaaaaagc tgaaaaagaa tatggaaatt ttgaaacgga tcattaccaa gttttgggag
    27601 attatcagaa aatcgtagac gataaccggt ttctcgtgat tgaaaggcag atcacccaaa
    27661 cagcagcaga tagccatgtt gaaaaaagat acgacacaat cgacaagaaa aacagtgtcc
    27721 agctctcact tccactttta ttcaaagatg acacctatct atctgttttg acaaaagaag
    27781 tcaaacggca gatggccgaa caagtcaagg aagatccatc taagtactat tggactgagc
    27841 aagatattca agaagggacg atagaaaaac caacacttgt tacgcctaca cgaagttttt
    27901 atttgaacaa agagcatcaa ttagttttga ctttttctca atacgaaatt gctcctggtt
    27961 atatgggtac accagaattt gtcattccta agtccgtgac aaaaacgatt ttggcatcgg
    28021 aagattattt ggatcattag acgagaagta gttgcgacta gcagtttcaa ttttcaagta
    28081 agtacaagta aataataaga agagaaaaag agaaagaaga gatatagtga aaagaaatta
    28141 tttagttatc agtattattg ctttatccgt gcttttgttt ttcgaaatta cttcggtggc
    28201 ctccttgatc accgaagtaa aaggacaaac acactcttcg gagcattcgt cacaatcttt
    28261 caaacaatca gaacaatcaa ccattaaaag ccaatcaact gaaacagcta acgtcaaaga
    28321 agccattcaa gaatcagcgg aaaaggtaca aagtcagtca tcacaatcaa cacaagacag
    28381 tacaaaaacg agccgagatc cggctgtcaa aagcgtcgca atcagctttg atgatggacc
    28441 aggagcgacc acaacaccgc agcttctgcg aatcttaaaa gaaaaaaacg tgcatgccac
    28501 ttttttcgtc ttaggagaaa atacggcgca gcatcctgaa atcgtgaagc agacagctga
    28561 agcagggcac gagattggca atcacacata cgatcatcag aatctggcca ctctttctgc
    28621 ccagtcgatg acggaggaag tgacgaaagc agacactgag atcaaaaaag tcactggcaa
    28681 aacccccact tttgttcgtc cgccctatgg ttctgtcacg aatgtaggag caacgatcat
    28741 ccagcgaccg atcatcgaat ggtctgttga ttcagaagat tggaagacaa gaaatcctga
    28801 tttgattttg cagaagatcc aagcaacagt atacgatggg gcaattattt tattccatga
    28861 tatctatcct gaaacgattc gtgccgttcc tcaagtgatc gattatctga aagagcaagg
    28921 gtatcgcatc acgacagttg gggatttatt agggcatcca acggctgtcg agaactatta
    28981 tggcagaaac gatcatcggc cagttcagta agtgagacaa gtatctttaa taaataacac
    29041 attttaataa gtagttgaac acataactac cttacttgca aaggcttaac aatatctata
    29101 caggtacaac aaaaaactgt ccaccaattt tctttggcgg acagttttca cttaaaaata
    29161 aagaagcaac tattcgtaaa ttatgctaaa atagcagtag aacgcgtcct gagggaatcg
    29221 aacccccgtc tcaagaaccg gaatcttacg tgatatccac tacactaagg acgcaagcac
    29281 tgggataatt gtaactaaac agataaaaaa ttacaagggg attggacaaa aaaatgaaat
    29341 ttgagcaaaa tttttcacaa aaacagcagc agacacagaa actagccatg acgcaacagt
    29401 tgcaacagtc catccaagtt ttacaatata acagtgagga gctgttggca ttcgttgaga
    29461 atcaagcaat ggaaaatcca ttggtggaag ttgttgagcc ggaatggcag ccagattaca
    29521 taaaagcttc ttcatcttct tatgaaggag aagagacaaa ttacctaaat cagattcctg
    29581 atacaaaagg gtctttattt gattcattga tcgaacaagt ccatttgaat taccgagata
    29641 cttttttgag gaaaatcgtt ctttatcttg tagaatacat cgatttgaac ggatttttga
    29701 cgattagttt agaagaagcc ggaaaagaga ttggagctac gcctatccaa atgctcgatg
    29761 cgttgactct gattcagcaa ttagaaccag ctggagtagg tgcacgtagt ttgcaagaat
    29821 gtctcatgct tcaaacagaa cgagatgatt atgcgccgga attagcttat atcgtgttgg
    29881 aagaatgttt tgaggaactg gtggagcgaa aatggaaaga aatcgcacaa cgtttttctg
    29941 ttgatctaca tgctgttcag cagatattcg actatttaca aacgttgagt ccaagccctg
    30001 gccggatttt cgaccgtagc agcgaattgt acattattcc tgatgtccgg gtattagtgg
    30061 acgacgataa aaatgtacaa gttatctcaa accgaaaaaa tcagccaaat atacgctttc
    30121 aagagagtta cttcaaacaa atgtcacaac aagcagataa agaaactgaa aattatttaa
    30181 aagaacggaa acaggaattc gaatggttga agaaaacgat cctacaacgt ggggatacaa
    30241 ttttgcgggt tgctcaagtc attgtttccc ggcaaaaagc tttctttatc gacaaggaac
    30301 gtccaatcaa gcctcttacg ttaaaggaag ttgcaactga gatagatgtg catgaatcca
    30361 cggtcagtcg tgcagtcaac gggaaatatt tggaaacaga cttcggtgta tttgaattaa
    30421 aaaaattttt cactacacga attcctacga atagtacaga acagacagaa gacctttcag
    30481 cagatacagc gaagaaaaag ctgcaggaat tagtcgatca agaagacaaa aacaagccgt
    30541 tgtctgacca gaaattggtt gaattgctga aaaaagatga gatagcgatc tcaagacgaa
    30601 cagtagcaaa atatcgtgat ttattaggaa tcccgagttc atcaaaaaga aaacgttatg
    30661 ataactaatc agtcaaaaga ctagaaaaag tatttcactt tttctagtct ttttagttga
    30721 aaaacgagag caaaactgtt agacttacag tcgtgaggtt gagatttccc tttattgatg
    30781 tgaaattcga atagttaatt tcttttttta tcgtatatgg gtcgttttaa gtctacattg
    30841 gacgtaaagt gtccaactaa ggagatcgct atgctggatg aaataaaaat gattgaatct
    30901 gttgcaccag atattatcga agtgttgcaa gaacgctata aaattttacg aaatatctat
    30961 tggatgcagc cgattggacg tcgaagttta tcggaaagta tggggatcac agaacgagta
    31021 ttgcgaacag aaacagatct tttgaaaaat ctgaatttga tcgacacctc aaaaagcggt
    31081 atgacgctga caactaaggg cgaagaagtt tatcaaagcc ttgaaaactt catggatcag
    31141 cttttaggta cgcatcaaac cgaacaacag ttggcagaat attttggtaa ccaacgctgt
    31201 atcgttgttt caggaaacag cgaagagcag accaaagtgg ctgatgcatt cggcgaagcg
    31261 ctgagcgaag ccctagaccg actacttcca gaaggcgaga atatcatcgc tgtgatggga
    31321 ggaactacta tggctgtggt agccgaacaa ttgtctaatc tggaaaataa gaaacggcat
    31381 aacctgtttg tccctgcaag aggcgggatt ggtgaagcga taactgtaca ggcaaattct
    31441 gtcagtgcaa gaatggctgc taaagcaaac ggtaaccacc gtgcacttta tgttccggaa
    31501 caattaagtc tggcaactta caattcttta ctcaatgagc catctatcca agaagtctta
    31561 aacttgatta gtgaagcgaa ttgtgttatt catagtattg ggcgtgcatt acacatggca
    31621 gcacgtcgta agatgactga aaaagaatta gtcatgctga aacaagcaaa tgctgttgcg
    31681 gaatcttttg gctacttttt caatgaaaaa ggtgaagtcg tttataaggt ccctagaatc
    31741 ggcatagaat tgcaagattt ggaaaaagtc ccgatcatca tggcaatcgc gggcggaaaa
    31801 tcaaaagcta aagcaattcg agcttatatg aaaaatgcac caaaacaaac gtggctcatc
    31861 actgatgaag ctgctgcaaa tgagatttta aaaggggtaa ccctttaaaa taaatatttt
    31921 tttgattttc ataaggagga aatcttaaat gacagttaaa gtaggtatta atggttttgg
    31981 acgtattgga cgtctagcat tccgtcgtat ccaagatgta gatggaatcg aagtagtagc
    32041 aatcaacgac ttgacagatg ctaaaatgtt ggcacacttg ttaaaatacg acacaactca
    32101 aggacgtttc aacggaacag ttgaagttca tgaaggttca ttcaacgtaa acggaaaaga
    32161 agttaaagta ttagctaacc gcaacccaga agaattacca tggggcgaac taggcgtaga
    32221 tatcgttcta gaatgtactg gtttcttcac ttctaaatca gcagctgaaa aacatttaac
    32281 agctggtgct aaacgcgttg ttatctctgc tcctggcgga aacgatgttc caacaatcgt
    32341 ttataacaca aaccacgaaa cattaactgg taaagaaaca gttatctcag gtgcttcatg
    32401 tactactaac tgtttagctc ctatggctaa aacattgaac gacaaatttg gtgttgttga
    32461 aggattaatg acaactatcc acgcttacac aggtgaccaa atgactctag acggacctca
    32521 tcctaaaggt gacttccgcc gtgcacgcgc tgctgctgca aacatcgttc ctaactcaac
    32581 aggtgctgct aaagctatcg gtttagtaat tcctgaattg aacggtaaat tagacggagc
    32641 tgctcaacgt gttcctgtac caacaggttc attaacagaa ttagtaacag ttcttgaaaa
    32701 agaagtaact gttgacgaaa tcaatgcagc aatgaaagaa gcttcaaacg aatcttacgg
    32761 atacaacaca gacgaaatcg tttcttcaga tatcgttggt atgacttacg gttcattatt
    32821 tgatgctaca caaactaaag taatgacagt tggcgacaaa caattagtta aaactgttgc
    32881 ttggtacgac aacgaaatgt catacactgc acaattagta cgtactttag aatacttcgc
    32941 taacttataa gatagacaaa cgtacaagtg taaattatag acatgtacat ttaaaagcgg
    33001 ggaagcaatc gcgcttcttc cgcttttttt gataataagt ttattcagga ggaaataaaa
    33061 tggctaagaa aacagtgaaa gatatcgatt taaaagacaa aaaagttctt gtccgtgttg
    33121 acttcaacgt tcctttgaaa gacggcgtga tcactgacga cactcgtatc aaagcagcat
    33181 tgccaacaat caactacgtt ctagaacaag gcggaaaagc aatccttttc tctcaccttg
    33241 gacgtgtaaa aacagaagaa gataaagaag gaaaatcttt agctccagtt gcaaaacgtc
    33301 taggcgaatt attaggtaaa gaagtaacat tcgtacctga aactcgcgga gaacaattag
    33361 aagaagcaat ccgcaacatg aatgacggcg acgttgtcgt attcgaaaat acacgatttg
    33421 aagatattga cggtaaaaaa gaaagcaaaa atgatacaga actaggtaaa tactgggctt
    33481 cattaggcga tgtatttgtt aacgatgctt tcggtacagc tcaccgtgca catgcttcta
    33541 acgtaggtat cgcttcaact ggtatcccaa cagttgctgg attcttgatg gaaaaagaaa
    33601 tcaagttcat cggtgaagca gtagaagaac caaaacgacc aatgattgca atccttggtg
    33661 gcgcaaaagt ttctgataaa atcggcgtaa tcgaaaactt gattcctaaa gcagataaaa
    33721 tcttgatcgg tggcggaatg acttacacat tctacgaagc aaaaggaatc aagatcggta
    33781 actctctagt agaagctgat aaagtggaac tagcaaaaga attaatcgaa aaagcaggcg
    33841 acaaacttgt cttgccaatc gacaatgtct gtgcaccaga attttcaaat gatgttgaaa
    33901 cacaagtaat cgaaggagac attcctgatg gtttgatggc tttagacatc ggcccagcat
    33961 cagtaaaatt atttgctgat acattacaag gtgcaaaaac agttgtttgg aacggaccta
    34021 tgggtgtatt tgaaatgagt aactttgcta aaggtacaat cggtgtttgt gaagcaatcg
    34081 ctaacttaga aggcgcaaca acaatcatcg gtggcggaga ctcagccgca gcagcagaac
    34141 aattaggatt tgctgacaaa ttcacacaca tctcaacagg tggcggcgca agcttggaat
    34201 tgcttgaagg taaagaatta ccaggactag cagcaatcaa cgataaataa acgaccaagt
    34261 ttgctcaatt ctgacgagta atcgaacaaa aggtgaaggg agttttcatg actccctagc
    34321 catttttcaa taaattaagg agtgtgttcc tcaatgcgta aacctattat cgcaggtaac
    34381 tggaaaatga acaaaactgc atcagaagca aaagaatttg ctgaagcagt aaaaaacaaa
    34441 atcccttcaa atgacaaagt tgattcagtc atcggatctc ctgcattatt cttacaagaa
    34501 ttaatgacat cagctgaagg tacagaacta aaaatctcag cacaaaactg ctactgggaa
    34561 aactcaggtg cgttcactgg tgaaacttca ccagcagctc ttgctgatct aggtgttcat
    34621 tatgtgatca tcggacattc agaacgtcgt gaatatttcc atgaaacaga cgaagacatc
    34681 aataaaaaag cgaaagctat ctttgcaaat ggtatgacac caatcctatg ctgtggcgaa
    34741 tctttagaaa cctatgaagc aggcaaaact gctgaatgga tcgaaggaca aattacagct
    34801 ggtttagctg atctttcagc tgaacaggtg tcaaacatgg ttattgctta tgaaccaatc
    34861 tgggcaatcg gtactggtaa atcagctgac gcacaaatcg ctgacgaaat ttgtggagtt
    34921 gtacgtcaaa cagttgaaaa actttatgga aaagaagtat cagaagcagt tcgtatccaa
    34981 tacggcggtt ctgtaaaacc agaaaatatt gctgaataca tggcaaaaga aaatgttgac
    35041 ggtgctttag tcggtggcgc aagcttgcaa gcagattcat tcttgtcatt gttagacgct
    35101 gtaaaataat tgttgaaaat ttgcgaaaaa tgcaagaaat gtttgcacta atgagcaaaa
    35161 ttaactaaaa tcgtatatga gggaaatccc ttaggaaaaa acaaactcaa aggagagaca
    35221 aaacatgtca attattactg atgtttacgc tcgcgagatc ttagactcac gtggtaaccc
    35281 aacaatcgaa gtagaagtat acacagaaag cggagctttt ggccgcggaa tggttccttc
    35341 aggtgcttca actggtgaat acgaagcagt tgaattacgt gacggagaca aagctcgtta
    35401 tggcggtaaa ggtgtaacta aagctgtcga caacgtaaac aacatcattg ctgaagcaat
    35461 cattggctac gatgttcgtg accaaatggc tatcgacaaa gctatgatcg ctttagacgg
    35521 aactcctaac aaaggtaaat taggtgcgaa cgctatttta ggtgtttcta tcgctgttgc
    35581 acgtgcagct gctgactacc tagaagtacc tttataccac tacctaggcg gattcaacac
    35641 aaaagtattg ccaacaccaa tgatgaacat catcaacggc ggatcacatg ctgataactc
    35701 aatcgacttc caagaattca tgatcatgcc tgttggcgct ccaacattca aagaagctct
    35761 acgtatgggt gctgaagtat tccacgcatt agcttcaatc ttgaaagctc gcggattagc
    35821 aacttctgtt ggtgacgaag gtggatttgc tccaaacctt ggttcaaacg aagaaggttt
    35881 tgaagtaatc atcgaagcaa tcgaaaaagc tggctatgta cctggtaaag acgttgttct
    35941 tgctatggat gctgcttctt cagaattcta cgacaaagaa aaaggtgttt acgtactagc
    36001 tgattcaggc gaaggcgaaa aaacaactga cgaaatgatc aaattctacg aagaattagt
    36061 ttctaaatat ccaatcatct caatcgaaga cggattagac gaaaacgact gggacggatt
    36121 caagaaatta actgacgtat taggcgacaa agttcaatta gttggtgacg acttgttcgt
    36181 aacaaacact caaaaattat ctgaaggtat cgaaaaagga attgctaact caatccttat
    36241 caaagtgaac caaatcggta cattaacaga aactttcgaa gctatcgaaa tggctaaaga
    36301 agctggctac acagcagttg tatctcaccg ttctggtgaa acagaagatt caacaatctc
    36361 tgatatcgct gttgcaacaa acgctggcca aatcaaaact ggttctctat cacgtactga
    36421 ccgtattgct aaatacaacc aattactacg tatcgaagac caacttggtg aagttgcaga
    36481 atacaaaggt ttgaaatctt tctacaactt aaaaaacaaa taattctttt ctaatgaaga
    36541 tacatgatcg actattgaaa gatagtcgag tatgatcact tagttaagta atcgaactct
    36601 ctacttgctg aaatatcagc aggtagagag tttttttgca actagcttct gtatatgatg
    36661 tttacaaaga atggtacaag aaaagatcat ccttgaaaaa ggaaagctaa caataactag
    36721 catcatataa gagcttttaa ggatagaaca gtagaatagg aatctatgag caagtcctct
    36781 cgtataaata aaataggagg gaagtagcag catatttttc ataaagtggc tctctttctt
    36841 catttttact ttggttgctc ctatttgaaa attcgagcac actcaaatac aataaaaaga
    36901 aatggcaagg gagaggatta gatgaaaaaa gaagaaaaaa tcgcgatttt acaagagatc
    36961 atccgaatta aatcagtgaa tggaaacgaa ggtgaagtag cagcctattt gaataagctt
    37021 ttggcaaagc atgacataac aggagagatt gtttcttaca gagatggtag agataatttg
    37081 attgctcgtt accaaaaggg ccaatcagga aaagtgttag gcctatctgg gcatatggat
    37141 gtcgtggcgg ctggtgatga atcgtcttgg acctatgcac cctttgcagc agaaatccat
    37201 gggaaccgtt tgtacggacg tggtgctaca gatatgaaga gtggcttggc agcaatggtg
    37261 attgccatga tcgaactgaa agagtcagga aaaccattta acggaacagt caaattatta
    37321 gccactgtcg gagaagaagt gggtgaacta ggtggggaac agctcacgaa agcaggctat
    37381 gtagatgact tagatgcctt gatcatcgga gagccaacca attacagttt gatgtatacg
    37441 cacatgggat caatcaacta tacagtcacc tcgcacggaa aagaagcgca tagctctatg
    37501 ccagaccaag gttataatgc aatcaatcac ctaaatgaat tcattacgaa agcaaatgct
    37561 gaaatgaatc acctcgctga aacaatcgag aatcctgtcc taggaaaaac aatccataat
    37621 gttacattga tcagtggcgg gaatcaagtc aacagcatcc caagccatgc gcagctccaa
    37681 gggaacattc gatcgattcc agaataccca aatgataaaa tcattgcatt gctgcaatca
    37741 atcgtcaatg aattgaatca agagacagac tatcatttgg aattgatgat cgattacaac
    37801 aaaatacctg tcaaagctga tccagattct cctttgattc attgcattca gcaacaattc
    37861 agccagccat tacctttagt tggagcggca gcaacaacgg atgcagccga atttacgaaa
    37921 gctaaccatt ccttcgactt tgtcgtcttt gggcctggtg tcgttacttt gcctcatcaa
    37981 gtagatgagt atgttgaaat cgataattat ttggatatga tcgaaaaata tcaaggaatt
    38041 attttatcct acttagcgta agattttttt aataaatgaa aaaacagagc cagattagca
    38101 tta
//
LOCUS       DACBYO010000019        37213 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.019, whole genome shotgun sequence.
ACCESSION   DACBYO010000019 DACBYO010000000
VERSION     DACBYO010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.019"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            68..808
                     /locus_tag="IVD26_000947"
     CDS             68..808
                     /locus_tag="IVD26_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP6078942.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1232..1402)
                     /locus_tag="IVD26_000948"
     CDS             complement(1232..1402)
                     /locus_tag="IVD26_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6078943.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1596..1775)
                     /locus_tag="IVD26_000949"
     CDS             complement(1596..1775)
                     /locus_tag="IVD26_000949"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078944.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            complement(1785..2009)
                     /locus_tag="IVD26_000950"
     CDS             complement(1785..2009)
                     /locus_tag="IVD26_000950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078945.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            2162..3274
                     /locus_tag="IVD26_000951"
     CDS             2162..3274
                     /locus_tag="IVD26_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP6078946.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3352..3645)
                     /locus_tag="IVD26_000952"
     CDS             complement(3352..3645)
                     /locus_tag="IVD26_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAP6078947.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3813..4127
                     /locus_tag="IVD26_000953"
     CDS             3813..4127
                     /locus_tag="IVD26_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAP6078948.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4148..6127
                     /locus_tag="IVD26_000954"
     CDS             4148..6127
                     /locus_tag="IVD26_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP6078949.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6140..6466
                     /locus_tag="IVD26_000955"
     CDS             6140..6466
                     /locus_tag="IVD26_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAP6078950.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6482..7000
                     /locus_tag="IVD26_000956"
     CDS             6482..7000
                     /locus_tag="IVD26_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078951.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7000..8352
                     /gene="celB"
                     /locus_tag="IVD26_000957"
     CDS             7000..8352
                     /gene="celB"
                     /locus_tag="IVD26_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP6078952.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8436..9941)
                     /locus_tag="IVD26_000958"
     CDS             complement(8436..9941)
                     /locus_tag="IVD26_000958"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAP6078953.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10033..10623)
                     /locus_tag="IVD26_000959"
     CDS             complement(10033..10623)
                     /locus_tag="IVD26_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP6078954.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10802..12448
                     /locus_tag="IVD26_000960"
     CDS             10802..12448
                     /locus_tag="IVD26_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP6078955.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12497..13216
                     /locus_tag="IVD26_000961"
     CDS             12497..13216
                     /locus_tag="IVD26_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAP6078956.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13695..14642
                     /locus_tag="IVD26_000962"
     CDS             13695..14642
                     /locus_tag="IVD26_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6078957.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14654..15574
                     /locus_tag="IVD26_000963"
     CDS             14654..15574
                     /locus_tag="IVD26_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6078958.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15615..17072
                     /locus_tag="IVD26_000964"
     CDS             15615..17072
                     /locus_tag="IVD26_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6078959.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17417..18031
                     /locus_tag="IVD26_000965"
     CDS             17417..18031
                     /locus_tag="IVD26_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP6078960.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18024..19748
                     /locus_tag="IVD26_000966"
     CDS             18024..19748
                     /locus_tag="IVD26_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6078961.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19745..21196
                     /locus_tag="IVD26_000967"
     CDS             19745..21196
                     /locus_tag="IVD26_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6078962.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21668..23821)
                     /locus_tag="IVD26_000968"
     CDS             complement(21668..23821)
                     /locus_tag="IVD26_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAP6078963.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23823..24869)
                     /locus_tag="IVD26_000969"
     CDS             complement(23823..24869)
                     /locus_tag="IVD26_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6078964.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            25019..26308
                     /locus_tag="IVD26_000970"
     CDS             25019..26308
                     /locus_tag="IVD26_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAP6078965.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26321..29023
                     /locus_tag="IVD26_000971"
     CDS             26321..29023
                     /locus_tag="IVD26_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAP6078966.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            29008..29865
                     /locus_tag="IVD26_000972"
     CDS             29008..29865
                     /locus_tag="IVD26_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6078967.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29936..30793)
                     /locus_tag="IVD26_000973"
     CDS             complement(29936..30793)
                     /locus_tag="IVD26_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP6078968.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            31004..33175
                     /locus_tag="IVD26_000974"
     CDS             31004..33175
                     /locus_tag="IVD26_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAP6078969.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            33243..33584
                     /locus_tag="IVD26_000975"
     CDS             33243..33584
                     /locus_tag="IVD26_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAP6078970.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33860..35614)
                     /locus_tag="IVD26_000976"
     CDS             complement(33860..35614)
                     /locus_tag="IVD26_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6078971.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35625..36461)
                     /locus_tag="IVD26_000977"
     CDS             complement(35625..36461)
                     /locus_tag="IVD26_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP6078972.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(36463..37146)
                     /locus_tag="IVD26_000978"
     CDS             complement(36463..37146)
                     /locus_tag="IVD26_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAP6078973.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        12002 a         6544 c         7632 g        11035 t
ORIGIN      
        1 ggggtatgaa ttagatgcga caccgatcga gtttgagatc gaaagaagtc agacagcggt
       61 ggtagaattg acgaaagcaa accgacttac accaggcggt gtcgtgttga caaagatcga
      121 tgaccaaagc ggggaagtcc tgcaaggagc tgtttttgag ttacaagatg ccaatggaac
      181 cgttctgcag tcaggtctaa ccacaggagc agatggaaaa ctggcgattg acggcttagc
      241 accaggagtg tatcagctgg tagaaaccca agcgccaacg gggtatgaat tggatgcgac
      301 accaatcgag tttgagatcg aaagaagtca gacagcggtg gtagaattga cgaaagaaaa
      361 tcgacttaca ccaggcggtg tcgtgttgac aaagatcgat gaccaaagcg gagaagtcct
      421 gcaaggagct gtttttgagt tacaagatgc caatggaacc gttctgcagt caggtctaac
      481 cacaggagca gatggaaaac tggcgataga tggcttagca ccaggagcat atcagctggt
      541 agaaactcaa gcgccaacgg ggtatgaatt ggatgcgaca ccagtaactt tcaagatcga
      601 aaaagaacaa gaagtggcga tctttttaac aaaagagaat agaaaagttg ctgatagctc
      661 agatataaga ggaaacaatc caacaagcag tggaaataag catcttccaa aaactggaga
      721 aaccatcatt agccagttta tattgtcaat attgggtgtg ctacttgttt tcatcagtat
      781 aaaatttaga aagaaacgaa atatatgagc taaaataaaa aattgaataa gcatagtttt
      841 taaaatcaac tagtacccat caattgaatg gaaactaccg attttagaag gggtatacaa
      901 acaaatatta gtatcggagt agagaaggtt gaacccaacc agtaaataag taaagacaat
      961 tttgtgctgc gttgagaagt gaaaaataaa cctttgtagt aatactagtt aataaaaaat
     1021 atacaaaaac actgcgaaaa tcattcttga gtttcgcagt gttttttgcc taatgactca
     1081 agtttattgg gtaatacttt gattttcttt ctacaaataa tcagcgatca gttgtaattt
     1141 tttctctagt tttaatggct ctttgtcaat aaggagaaaa acaagtcggg tcttttgtct
     1201 cggaaagctt caaccaactc gtgaataaag gttacgcctc cttgaaaggc gtggaaaaac
     1261 caagtaatcg atcaatcacc aatttcgcat ttggtagaac atgtttggtg agctgaaagt
     1321 aggtggcgtt catgtctgta actaagaatt ctatttcttt aggattagtg cagctaagga
     1381 aatagtttgt taatcgagga attttttgtg taggtaaatt ttctcgatta atttttctgt
     1441 ctcgccatcc gcggaaataa aactcagttt atcctcaacg gaaacgtgag aacgaaattc
     1501 acaaccctca acactcaaga cagaattctt ttggaagact ttggtaaata gcttctcaac
     1561 tctttcaatg tgcgaataac ggttgtcaaa gatacctaac aacttttcga aataaaaaat
     1621 aacgacactt tttcagtcag taaagaagtg attttatgtc tgacatgatt tgaaatcgag
     1681 tgccttggac ggataaaata actttgagcg ttccaatggc ttcgacagtt tttacaggta
     1741 tagcgctgct tttttaggcg tataaccatt ggcatatgat tatattattc aaagtggaca
     1801 atggtttcct tcttcttgtt tttcaccacc attaatttcc tatttccatc taccacagca
     1861 gaaccacaat ttctacagac acatggagca gggaagagaa ctgcagcaac gatcaatgtt
     1921 tttttcttct gtaaggtttc gtaagagacc tctgtaatca tcaaattttt gtctattgat
     1981 ctcagaattt ttttgataga accattcata aagcatatcg ttctctcagt tgtttatttt
     2041 gtggtgattt aatcatacaa gaaaacgata tgttttttta taaaaacatg aataggaaaa
     2101 atagttgaca agaaaatgac aacgccatat gatgttccat agtatttaca acctgtcata
     2161 gatgactgta aaaaataaaa gtaaaaagaa aggacgacaa caggtggatt tttatcagtc
     2221 tctacaacta gatccgttta ttttaaaaca aaaaatacga gaagcagctt ctaaaaaaga
     2281 aaagtgcatg tatatttgtt cattgttttt acgatcatta ttcatcgtat tgtttgccat
     2341 ttgttttatc attataatta caacattatt tgaatcgaag cataaaccat acgctgtggt
     2401 tttattctgt atgttgatga gtattcgttt tgttgacttt ggttataaga tttcccattc
     2461 gatcataggt ttagcaatcg tcatgttctc actattagta gcaccgtatg tccagctgat
     2521 caaatggtca gttatgggca tgttgattca ttttatttta ctaagcagca tattaatggc
     2581 aaccgctagt gatcccaaaa tggggaatgc ttctttgtac ggcttttcat atctctttat
     2641 tgtttattcg ttacctaaag attcgttgaa caagaatttc tttacacaaa caagtagctt
     2701 attatttttg tttttttgtt ggttttcagt tctcctttac agaaaacatc gagaaaagaa
     2761 caaagacaaa agcttgttta aagagatttt tttgaaaggc atgtattcgc aggaaaaaat
     2821 ttggatgctc atctatgcat ttggcattag tcttttgatc gttgcaggag agtatgtccc
     2881 ttttcagcga ttgatgtggg cagggtttgc attttcttct attgtatcta gctatggatt
     2941 gatgtcgatt ggtttcaaag aacgagcagt agaccgaatc attggctcat tgattggatg
     3001 tgttttattt attggtatca gccaatttat tccttttaac tgggtcggta tattaggtgg
     3061 tctagcttta ggtgtttgtt ctacctatag atataaaaca gtttttaatt cttttggtgc
     3121 tttggcaatc actgccagtt tattcggggt tccaggagca gtaacgatcc gcatttttga
     3181 gaatatcctt ggggtatgtt taggaatcat gtatattggg gtgactgaaa tacttatccg
     3241 aaaaataaga gaaaaacacg gtttgaatca ttagatgaga tcgaataaaa aataaggaaa
     3301 aagtgaagat acacatggat gataaattgc tatcattcca tgtgtatctt tttacggtaa
     3361 atcagtgaaa cgttcgactt tcatttttaa tttatacttt ttacggagtt cgtttatttg
     3421 agccatcatt tcggatttgt gatgcttttc gattgcttct tcatctttcc aacggtcgat
     3481 cagtaaaaga gattctggat cttctagtgg aaagtaatag tcatatttct cgtttccttc
     3541 ttctgcacga atcgctttga caatgtttct ttcgaccatt tcttctgcaa attttctggc
     3601 ttgtccattt gtacttgtat acaaaatatt cactgtgata ctcactaaat cccctcctga
     3661 aaaaattcta tcactagtat atcacggtgc cagaaattat tattcaagat atgatacaca
     3721 ttttttccgc aatgctacgg aaatatatat tttgaataga aaacgcttac aagatatgct
     3781 tggtttataa aaataaaagg agtgattgat ttatgaaaaa agcattgatt atttgtgcgg
     3841 caggaatgtc atcctcgatg atggcctcaa agacaacgga tttctttaag caaaaaagag
     3901 aagaggtact cgtagatgca gtttcagcta cagaaggcga taatatgatt aagaatagtg
     3961 attttgattt atttctgatc agcccgcaaa cgacgatgtt tttggataaa ttcaaaaaat
     4021 taggagaatc tgttggaaag cctgttgtta gtatcccttt ccaagcgtat gtcccaatcc
     4081 ctacaggcat ccagaagtta gcagaggtga tcgaagagaa catatgatgg aataggagtg
     4141 gatgataatg aaacagaagg aaaaattgct gttgagatat ttgattgatc acaagaagga
     4201 gtatgtcacc agtcaacgtt tagcttctga attgttatta tctgatcgga caatccgtaa
     4261 ttacttgcag cggatcaaag agttagtaga aaaaaacgga ggtaagatca ttgctaaacc
     4321 aggttatggc taccaactgc atattttaca aagactgaca tttgacttgt ttttgagtcg
     4381 gcaagaaata gtacctggat atgctagaga accgcaagga ttttatgagt ccgaagatcg
     4441 acaaaagtat atattgaacc aattgctttt ggaagatgcc attcttttta tggatgattt
     4501 ggcagaagag ctttatatca gtcgttccag tttgacaaag gacatgcaag aaatcaagga
     4561 gcgattgatt ccatattcac taaaaatcgt ttctaagcat ggtcaaggga catggatcga
     4621 aggggaagaa agaaatcgac ggcattttat catggatact ttttttggaa accattatgg
     4681 aaattcattg aaagaatatt tagggcaaag ccgttttttc ccagacatca gttttgaaga
     4741 gctagtcatt atcattctcg atgaaacaag agaagctaag ttaaaagttt cggattttat
     4801 catacagaat ctgactttac acttggcttt ggggatcaaa cggctccgag aagggtttga
     4861 aatcaaggaa ttaggcatcg aacaagaagt ttctaagcga gtagagtatc aagtggcgca
     4921 gcggatcgtt caacgtattg aggtaatcgc aggtgtatcg tttcccgaag aagaaattgc
     4981 ttatttgaca ttacatctca tggctaagtc gaatcacaaa gaaaatcaaa atgatcagga
     5041 actatcaaag gaattagcga aagttctgaa aagattgtct caggaatttc atttttcatt
     5101 agtagaggat ctccagcttt tcaatggact actcgatcat ttgtcaccga tgatgattcg
     5161 attgagccga ggtattcgca ttgagaaccc attgactgag gagataaaga aagaaaatcc
     5221 caaagtcttt gacgcagtaa aaaggcattt cagcaacatg ccggctttga aaaactatac
     5281 catcaatgaa gatgaatggg cctatttggc tttgcatctc atggcggcat tggaaaaaga
     5341 aagagctgcg cataaactac atgcattgat tatctgtgca acgggttacg gcagtgccca
     5401 actattaaag aatcgcgtag tcagtgaatt cggtaaaaat attacagtgg taagtgtaaa
     5461 aggctattat gagatcaatg aaacaacttt aaaaggaatc gacctgatta tttcttctat
     5521 tgatctttcg acaatgtttt tcaaaattcc agttttacat gtcagtattt ttttgaatga
     5581 agatgatgtt cgtaaaatac gaaaggtagt tggagaatct ataccctatc attcctcaga
     5641 tagaccgata ccagcatttt ctctacagca aaaaaagcag atttacaccg aacagttgtc
     5701 tgaaaaattt ttcaagactt atacgtacga accgaaaaag gaagaaattc ttcatgattt
     5761 gctgcaaaag ctgagcataa atgaagaaga aggatatata agagaaatgc gaaagcagat
     5821 ccagcaacgt gaaaatatgg gacaaatcat attcagtgat acagtggcag tcccacatcc
     5881 cgctgttcca gttggaatcg aaacaaaggt agccgttgca ttgattcctt ctgggatgca
     5941 gtgggatcaa tatcaagaaa ttcattttgt ttttttagtt tcgccttctt atgtcgaaaa
     6001 tgaaggaatt acggtcgtga ctaaagcaat cgttaggtta gttgaccagc taaaagtaca
     6061 gcaggaaatc ttagctgaac ctatttttga gaatttcagc agtaaattta tcaaactgat
     6121 cgaataagga ggaaaacaga tggctgaaaa aataaacagt gaaacactac aagtgacttc
     6181 ttttgatatc attttccata gcggaaatgc acggacactg atacatgaag catttcgctc
     6241 gatgcgtaaa gagatgtttg aagaagtaga agagaagttg cgacaagcaa atgaagagat
     6301 tcttcatgcg catcagtcac aaactcaact tctgaaagaa tatgccagcg ggacaaaaat
     6361 agaaatggaa attatcatgg tccatgcaca agatcatctg atgacgacga tgacattatt
     6421 ggaagttgca caggaaatga attatttgta tcaaaaaaat aaatagaaag gaaggatcat
     6481 tgtgcaggat acagtaaaaa ggaaaatcga attagaaaaa aagcaactta gtttgaaaaa
     6541 catgtatttc aatcgttatc taatcgtacg ttacctgact gcctttttct ttttcatgaa
     6601 catgcaatgg atgattctgc ttctatcagc taaaagttta ggaagtagtt taccgatgat
     6661 tctgatttta gctattttgc ctgcagtagg agaacaagta aagctttatc gaaaacacca
     6721 aacgaacgtt ccatggacaa agtggtattt tttgttccag agtgtcttta atttattagt
     6781 gattccagtg ttgtttacct caggatttac attcttgtat ccttttatgg caaataacaa
     6841 tggaggacag ttatttgttt tcattcttgt tgtaagcggt atttttgcca gtgcatttat
     6901 acagtatcgt ttaaagaaaa tttcactcaa ccaagaccaa cagtatatcc gtattaaaca
     6961 atatgaaaaa gcgttatatt taggaaagga gaataactaa tgtttgattt tttgcagaaa
     7021 tacctgatgg gacctatggg gaaaattgcg caacttaaaa tcgttcgggc tgtcatggca
     7081 gcggggatgg cttctattcc tttcacgatt gtaggctcga tgtttttggt tttaaatatt
     7141 ttgccattac cgttcccatt tttagaagga ttttttaatg caactttttt caaagttagt
     7201 gacttgtaca tgatcgtcaa tacaatgacg atggggattt tatctattta ctttgccatt
     7261 gtgtttgctt atgaattaac gtcaattgaa cgagatgaac aaaaattaaa tgttaatccg
     7321 ctcacggggg cattactatc tgtttttgca ttctttatgt gtatccctga attgatcatg
     7381 actgatggta aaatcagctt gattgcttct atcaatgaga cagaaactgt agtaaatggt
     7441 attaggatgg gctcttttgt cgaacgttta ggaacttcag gaatctttac agctattatt
     7501 atgtcgatta ttgcggtcga attgtattgt atgtgtgtca agagaaattg ggtcataaaa
     7561 atgccagatg ttgttccgcc aggagtttct cgttctttca ctgctctgat cccaacattt
     7621 gtcattgcgt ttgtggtgat gatcatcaat ggattattag ttgcactagg aacggatatc
     7681 ttcaaaatga ttgctatccc atttgggttt gttacgcagt tgacgaatac atggcttggt
     7741 gtcatggtga tttatttctt gatccatgca ttgtggatcg tagggatcca tggagcgaat
     7801 atcatcactt ctttcttgac cccgatcgta ttagctaata tggcagctaa cgcacaaggc
     7861 gcaaattatc cgttggcagg agaattcaac aattcttatg taaccgttgg tggatcaggt
     7921 gcgactttag gattgatcat ctttattgca ttcctcgcga aatctgatca gctgaaagtg
     7981 ttaggaaaag cctcacttgt accaggatta ttcaatatca atgaaccaat cattttcggg
     8041 atgccaatcg tctacaatcc ctatttagcg gttccgtttt tcttagctcc gatggcttct
     8101 gctacactcg cttattttgc cattcggctg gaaatcgtca aaccgatgct tgcacagatg
     8161 ccgtggcctt caccagtcgg gatcggagca tttgttggta gtggtggtga ttggaaagct
     8221 gctgtgttag cagtcatttg tgcaatcatc gcattcatta tctggttccc atttatcaaa
     8281 ttctatgata ataaattatt aaatgaagaa agagaaaagg cagcagaatt agctagtgaa
     8341 aagttaaaat gatttctaag aaaaaaggaa ctgtgacaaa aaatcacagt cccttttttt
     8401 cttagaaatg ggaaaccact agtatataaa taccattatt cttcaatcaa ccgcttcacg
     8461 attgcataat ccccttcata aggttcatct acaccattga ttttttgata gggatccacg
     8521 ccttttcccg caataacgac tgaatcttgc ggagcgcttt ctgctaaagc gcgtcgaatc
     8581 gcttcaggac gatccatttc ataatgaacg atcaaatctg gattagtaat tgcttcattg
     8641 atttcttccg cgattttttt cggatcttca aatgctgggt catctgccgt caaaaaggcg
     8701 atgtcagctg tttctgatag cacttttcca aaatcatgtc gacgggagat tgctttgttt
     8761 cctgggctgc ctaatacaac aattacacgg ccatctggat gttcattttt ggcaaatttc
     8821 agcaatgttt tcaagcttag ataattatgt gcatagtcca catagacatg cgctccattg
     8881 gattggatca attgatccat tcggcctggt acacgagctt cttttaatcc gtcttgtgca
     8941 tcttgactgg aggcacctgt tagtgctgcg gcaatgatcg cactggctgc attttcttgg
     9001 ttgaatcctc cagccagcaa aatatcataa gcagtatcgc agatagctaa gcgatcttca
     9061 tgagaagata aagtaaaacc gtgagtacct ttatctgaac ggatcacttg ataattgctt
     9121 tcttccgaac gaccataagt gatcgttgga atctggaata gatcggctgt ttccctaagt
     9181 aaatcaaaat agtcactttc atgatttaaa acaactgttt ttgaattcaa gatcaattgt
     9241 cgcttgcaat agaaatagtc atcaaatgtc ggatgttcga tcggactgat atggtcaggc
     9301 gagatattca agaagattcc gacatctaaa gtcaagccgt atacgcgttg tgttttgtaa
     9361 gcttgtgaag aaacttccat cactagatga gtcataccat tttcaactgc ttctgacatc
     9421 atacgatata aatctaatga ctcaggcgtt gtcaaatggg atttgaaata tgttttgcca
     9481 tctaacgttg tattcatagt agaaagcaat gctgtttttt tatttgttgt gtgatccaag
     9541 attgcttttg taaagtacgc agcagttgtt ttaccttttg ttccagtgaa tccgatcact
     9601 ttcaatttat tttgcggata gtcgtaaaaa gccatagcaa gaagcgccat tgctttacgg
     9661 atatccgtta cgatgattcc tactgctgaa ttttcgtatg gttgttctga tacataatat
     9721 tgaataccct gttcgattgc tgaatccaaa tattcttctt tgaaattcat tcctttacag
     9781 aaaaacaaag tagaagcatc agcttttctt gaatcataac ttaactgaag aaattcagct
     9841 ttttctggta catcaagatg ccagcctctt gttgaaacaa attcttttaa tagattttct
     9901 tttaatagta aatgacggat gtcttctaaa gagaagctca ttgattgatc cctcgcttta
     9961 ttcaatttct tggtttatta tagcacactc tttttaatat atcgtttgtt tccgctatga
    10021 caaaatccag ctttattcaa attttcttga cacaggggac aagcggatga gtattttcat
    10081 aaacaatgaa ctgactgtaa tagataggag aacgaatagt gtctccaaca atccaaaaac
    10141 ataataattc aaaaagacga taagactatt ggtaagtaaa agtccttgcg gcattggaag
    10201 ccgaaaaaat ttgtggaaaa taatcggcgg tatcgttata ccgccatttg aggccccgac
    10261 tgtgtacaat gtgtaaaccc caagactgaa caaaagactt cctgaaatca gtgaaaagaa
    10321 atgtgaggag atcatttcca cttttggaac aatctctaaa acaacaggaa aaagcagact
    10381 tcccgctaca gtcttaaaaa atactgattt tcctaatagg acagcggcta gaagcagcat
    10441 cataagattg atgctccaaa cagtaactga gcgttggata gaaaaggccg tttcaactaa
    10501 atgtccgatg gcgcccactc cggcggaagc tatatcgtga gggagcaaga accaattcaa
    10561 tccaactgtg ataaagaaaa gacctaaaaa tataacgggt agttttttta tttcttgtgt
    10621 cattgatatc tcctataaat gttagccata aaaggctgta tatttcttta ctttaccaaa
    10681 aaaacgaaac cgaattcaaa aaaacaattg ttcttataaa agttatataa aatcgattgc
    10741 cagtttctgt tttaccaatt aaaatgatag taatgttttg tagaaagttg gaatctgacc
    10801 gatggataat caaagaaaac cagcattaga tcaattaaca ccgcaagaaa aaatggcacg
    10861 aggctctgct tggatgaccg ccagtaatat catttcaaga ttgctaggcg ctgtctatat
    10921 cattccctgg tatgcttgga tgggcgaaaa tgctaaggct gccaatggat tattcaatat
    10981 gggatacaat atatatgcat tgtttctact gatctctaca gcaggaatac ctgctgcgat
    11041 tgcaaaacaa actgcacgct ataattcatt gaatgaatat ggcacttcac gacgattatt
    11101 tatccgtgca ttacagatga tgggcgggtt aggcctgttg tttgctttgt tcatgtacat
    11161 cgcctctcct tggctagctc atgcttctgg tggcggagaa gaactgattc caacgatgcg
    11221 ttctttgagt atcgctgtat tggtttttcc ttgtatgagt gtgatacgag ggtatttgca
    11281 aggcaatcaa gaaatgatgc cttatgcgct gtcgcagatt gtagaacagg tggcacgtat
    11341 tttttatatg ctattggcta cattcatcat catgaaagtc atggatggtg actatgtgac
    11401 ggcggtcacg caatcaactt tcgcggcatt tatcggtatg ctagcaagta ttcttgtcct
    11461 tttgtatttt ttgaagaaac atcaagcgta tacatcggcg tttattcact acagcgaaaa
    11521 caaaataaat attgcaacga aggaattgtt gttagatacc gttaaagaag cgattccgtt
    11581 tattattgtg ggttcagggg taacgatctt caaattagtc gatcagttca cttttatgaa
    11641 gatcatgtct gcatccaccg agtattccaa tgcacagtta ctggatcttt tttcgatttt
    11701 tagtgccaat ccagataagt tgacgatggt agttattgca ttggcaacat cgatcgcgtc
    11761 tactgggtta ccgttgatta cagaagctgt tacgttgaaa gatcgagtag gtctggcaaa
    11821 attgacaagc ggaaatttac agttgttttc attttttatg tttccggcga catttggtgt
    11881 tatgttactt gcctatccgc taaatacatt attttataca ccggattctc taggaagtaa
    11941 tgtactgatc caagcaagtt ttgtaggact cttcctagga ctatatatgc tagtttccaa
    12001 catgctgcaa ggaatgtttg aaaacaaggc ggcaattaat tatttggtta ttgggtttct
    12061 agtgaaactc cttcttcaat acccagccat tcgtttattt gaagtatacg gccctttatt
    12121 ggcgacaatg atcggatttg ctgtgtcttg taccttgatc ttaaagagaa tccatgaagt
    12181 agcccgcttt aaaccaagtt ttgtctggcg caggacattg ctgatcttta ttcttacctt
    12241 gattatgctt ttggcttcgt ggatcacaaa gatgattttt ggtgcttttt taaacgaaga
    12301 tagcaaattc cagtctctat tgttgattct tgtagtagca ggtatagggg ctttagtgta
    12361 tggttattta gctttgaaaa tccgcttggc agaaagacta ctaggaccag gaatagcgcg
    12421 tttacgacat aaattaaaaa taaaataagt gaatcagaag agctagattg atgctctttt
    12481 gaaatggggg aaacgcatgc gtttagataa gtttttagca gatatgggac ttggcagccg
    12541 caaagaagtc aaaggattaa tcaaaaaagg aacgatcgaa gtcaatggac aagtggtgaa
    12601 aagcgataaa gcgcaagtaa atgaattcga agatgcggtt acttatttag gagaaatcat
    12661 tacgtatcaa aaagattttt actacatttt gcataaacct gcaggagtca tttctgctac
    12721 tcaggataat catgatcaaa ccgtaatcga tttattggaa gaccaggatt atcgggaaga
    12781 tctttttcca gtcggccgat tagataaaga cacagagggc ctcttgattt taacgaatga
    12841 cggggtgttt gcccatcagt tactatcacc taaaaaacat gtggagaaag aatatctagc
    12901 tgaggttagc ggtataatga cagaagaaga tatccgttta tttgcagaag gactgattat
    12961 tgatggcgat gagcagacat tgccggcaaa actccaaatt gatcaagtag atcaagagac
    13021 agaaacttca attatccgtc tgattttgca tgaaggaaag tttcaccaag ttaagcgaat
    13081 ggtcaaagca gtaggaaaag aagtcttata tttaaaaaga atccgtatgg gaaaattttg
    13141 gctgcctaaa gatttgaata aagggcaata tcgacccatg accaaagaag agctagaaca
    13201 agtgagagaa aaataattga atggatagct aaaagaataa gcagagtagt tgtagcgcca
    13261 tctgaaaagc agacttgtcc gtctgacttt cggatggctt ttttgtgaaa tttcggctta
    13321 tttccgtaga agctacttct ggaacaccgt ttgttcggaa taagggactg tgacaagact
    13381 tttgttacag tccccattgt tccttgtgac tcagagttag atagtaagga cacgatctcc
    13441 ctaatactca ggccaaaacg ctgaattcac aacctctgat aaacggtgtt caatcagctg
    13501 accctcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttccc gtttttttct
    13561 ctaatactca ggccaaaacg ctgatttcac aacctctcct atactttgtt tcattttccc
    13621 tatactttgt ttatttattc tcattattga aagcgctata attacgttgc gaatgaatcg
    13681 aaaggggttt ttagatgaaa aaacgaaagg ggttcaatca tttttttatg aatctatggc
    13741 gttataaagc acttgtcctg atggctgtac cgggtatgct ttggatgatt tttttctttt
    13801 acatacctgt aatggcgaat gtcgtagcat tcaaaaattt tcatatttca gcagatgggt
    13861 tcttggctag cttgagggaa agtccttggg tgggttggga aaatttcaaa tttttatttt
    13921 cttcggatca agcatttctc atcactaaaa atacaatttt atataatgta gcatttatcc
    13981 ttttgaatct gctgatctca gtcgtatttg caatcattat gagcgagttg agaaataaac
    14041 gactcgttaa agtttatcaa acgatgtcct tactacctta ttttctatct tgggtcatta
    14101 tcagttactt tgtttacgct tttttaagtc ctgacaaagg aatattcaat cagtggatca
    14161 ctggacatgg aggagaagct gtcaattggt ataatgaacc gaaatattgg ccgtttatct
    14221 tggtgttcat tggtacatgg aaagggattg gttataacag cattatttac tttgcatctg
    14281 ttatgggaat cgatccgact tattatgaag ctgctatggt tgatggagct agcaaatggc
    14341 agcagatcaa acatgtgacg ataccacaac ttattccact aatgacgatt ttaacgattt
    14401 tagccgtagg aaacattttc cgagctgatt ttggcctgtt ttataacatt cctaggaatt
    14461 ccggtgcatt atatgatgtg actcaagttt tggatacgta tatctacaat ggcctgacat
    14521 ccacaggaga ttttggtatg acggctgctg caggacttta ccaatcagtt gtcggctttg
    14581 tcttgttgat gatcacaaat acgatcgccc gacgttttga tagcgattct gcattattct
    14641 aaggaggaaa aaaatgaaaa aaaagaaagt ggagagagtc caagtccgct ctttcaataa
    14701 gacggctaat tttttctcta atataatgat tgcactcttt gctatttcct gtattttgcc
    14761 atttatattt gttatcgcca tctcttttac cgatgagtcc atattgtcga ctcacgggta
    14821 cagtttttgg ccagaaaagt tcagtatatt tggttatacg tacttgttcg accagatgca
    14881 ggataaaatt ttccaagcgc ttttcgtcac tgtacttgtt actgttttag gtacactgat
    14941 caatagcacg gctacttctt tatatgctta tgcgatttca cggtcaaact ttccattccg
    15001 tcgttttttt accgtttttt gtttgattac gatgttgttc tcaccaggga tggtggccaa
    15061 ttatcttgtt atgacaaatc ttcttcagtt aaaagatacg atttgggcat tgatcttgcc
    15121 aatggctgtc agtcccttca atattattgt gatgcgcaca ttctttaaac gttcggtctc
    15181 tgattcgatt attgaatcgg cacggatcga tggagctagc gaactgcgaa tatttgttca
    15241 gatcgtttta ccgttagctg ttccaggtat tgcgacaatc agtttatttg ccgcattggg
    15301 ttactggaat gactggttca atgctttact ctacatccaa gatgataagc tagttccact
    15361 acagtatctt ttgatgaaaa tccaaagtaa tattcaatat ctgacacaaa attcaggagc
    15421 aggaagccaa ttgacaggcg gattagcctc agttccagga gaatctgcca gaatggcgat
    15481 cgtagtcatc tcgacgttgc ctattgcgat cagctatcca tttttccaga agcattttgt
    15541 caaaggtcta acaatcggcg gagtaaaaga ataaagaaac aaaaatataa atcataaaat
    15601 taggaggaag aaaaatgaag ttatggaaga aactagcctt tacaggtgtt tcagcgttgt
    15661 tgttgggaac attagcagca tgcggaggtt ctggttctaa agaccaggca gaagctagca
    15721 attcggacac tttgcagatg tatcaaatcg gagataaacc agataatttc gatcaattga
    15781 tggaagtagc aaacaaacga atcgaaaaag agatcggtgt aaaagtcaat atcaattaca
    15841 ttggctgggg cgattacgaa aagaaaatga acgtcatcat ttcttccggg gaaaattatg
    15901 atatcgcctt tgcgaacaac tatgtttcca atgcccaaaa aggagccttt gctgatttga
    15961 ctgaattagc gcctaagtac gctgaaaaag cttataatga tttagatgaa gcatatatta
    16021 aaggaaatct ggtcaatgga aaattatatg ctttcccagt caatggaaat gtctttgctc
    16081 aacaagtact tacttttaac aaagctttac tagataaata cgatctttca attgatggaa
    16141 tccaatctta cgctgatgca gaaaaagtct tgaaggaatt ccatgaaaaa gaaccaaaca
    16201 cggcagcttt tgccattgga caaggcttca aagtccaagg gaactttgat tatcctttag
    16261 ggaatacgtt accatttgct attgatctgg atggagatga ttcgaaaatc atcaaccaat
    16321 acgataatga aacgtatatc ggactgttac gtacaatgca tagctggtac aaacaaggac
    16381 tcattccaag tgacgctgca acgagcaata aggattatcc actagaagga aatacttggc
    16441 taatgcgtgg agaaacacaa ggaccgtatg attatggcga tacaattttg acaaatgcag
    16501 caaaacaaga acttgtctca aaagcaatta ctgttccact aaaatctaca gctcaagcac
    16561 aaatggcaaa ttttgtcgta tcaaatactt caaaaaataa agaaaaatca gtagaacttc
    16621 tagggctgct taacagtgat ccagaattat tgaatgggct tgtttggggg atcgagggag
    16681 aagcatggga aaaagtcgat ggttcagatg ataaaatcaa attgctagat ggttatcagc
    16741 caaatacaca tatgtctgct tggaatacag gaaacaacaa gattctatat acacaagagt
    16801 ctattacgga tgacatgatt gccaaacgtg atcaatcgat tgctgatgca gaaacttcac
    16861 cgattttagg attcagcttc aacactgaca gtgtcaaaac agaattaagt aatatttcta
    16921 atgtcatgaa tcaatattta gatggattga atacagggac tgttgatcca gatgaaacat
    16981 taccgaaatt gaaagacgct ttggacaagg ctggctatga taaggtattg aaagaaatgc
    17041 aaaaacaata tgatgagttc cgacaagaat aataatgaat aaagacaaag gggttgtgac
    17101 aaaagacgtg tcacaacctc ttgttccgaa taaacggtgt tcaaaagcca gtttctcggt
    17161 attaagctaa atatatgtaa aaatgtggaa agccatattc acaaaatttt tcttactact
    17221 cgaaactaag cggctatttc acaaactctt ggtaaacggt gttcaatcag ctgaccctcg
    17281 gtattcgctc acaaaacgac aaaatatgag gaactatttt tccgtttgtt tctctaataa
    17341 tcaggtcaag gtgctgattg cccaaccttt ttttgtataa tgagaaagta taaacttaat
    17401 gtttggagga gaagatatgt tagggaaggt tttggaagag ttatttatcc ggatctgggt
    17461 cattataaaa ctaaccttgt atttctggat atatacattt gccggcggga tcatctttgg
    17521 attaggtgcg gcatggaaaa cagtcaatga actattttat ttgtacggat tcgagtataa
    17581 agaaatcaca ataaaaagag gctggaatat atataaaaga aattttttaa gaggcaatct
    17641 gctatttagt ttatttttat ctggtactgc tttattgagt tacaatttat atttatctgt
    17701 tcaaatcaaa gggctcattt ttttagctat tgattttatt ttactttttg ccttgctctg
    17761 cctatttgct acttatcaat acagtatgat tttagatagt gaatatacga tctctgttcc
    17821 taatctgcta aagctaagtt ttatttcggt tttttccagc ttttcgtctt ttctaaaaat
    17881 aattattggt agcggtataa ttttaggcgt gacttggcaa ttcaaaggat tgatcctgtt
    17941 tggtgtcatt ggtcttttga cggtttggaa tggtacgatg acaacacatt ggcgtgaaga
    18001 attagataaa cagttggaaa gttatgaata agtttcggat tctattttca aaaggaacct
    18061 tactaaatcg tctgttgcgg aaatacgcgg ttatcatgat cggtgtaacg atgactgcta
    18121 ccgttatttt tagtatccat acttgggaac aaaatcaaaa acaggcagaa aacatgacaa
    18181 gtgatgccgt tcaaagcaca agcagaatgc tgaatgataa aacaaccttg agtaggatca
    18241 tcaaaaacca gcttgtaggg aattccgaaa agatcgaaaa tgtgacgacc tacttaacaa
    18301 aacccataga tcagtatctg atgtatgtat acgaacagca aaacagtacc gatgaattag
    18361 tttctttccc aaatcaaatc aaagatctct acgcaaatta tgaagaacta agtgcgatat
    18421 atatcgtgtt gaatcaacta ccggagtatt atgaatcttc tagagaaaac aaaggtgggg
    18481 aaataaaaaa ggggacacca aaattactag acgcctttta tatcaagttg cctatcacac
    18541 aaggaggagc tgagtcagga agtattttta ttggttttca aaagaaagaa ctagatatga
    18601 ttttagaaaa tctaacgtca ttcaatggac tctctttata catgatttct ggaacgacaa
    18661 atcgactata cacattccat gataataaaa tagctaaaga aacgtttgaa agacaagaaa
    18721 tgatcatcac agagagtctg aagaaaaatt cacaattgcc gattgacgat ctggaaaaaa
    18781 acaattttgt tcaacaccaa gaactgtctg atgattatcg tatattagct gtactagata
    18841 aaaaaagtgt aaaaatcgaa acgggaaaaa atcttgcccc gctgatcatt ggtatcatta
    18901 ttttagacaa tatactgctt atctttcttt ataaaacatt caaacgatat tcacagcaag
    18961 tatctatcgt catgcaggcc atggatcaaa cagcagcagg gaatttagag acgcggatcg
    19021 acataacaaa cacggaatat gaactgaagg aactttcaat cggtatcaac gaaatgttgg
    19081 atagcatcaa tcagtttgta gaagacatct acaaattaga aatcaaacag caagacgcac
    19141 atatgcgggc gcttcaagca cagatcaatc cacacttttt atataataca ttagaatata
    19201 tccgaatgta tgcaatcagc gaaggaagtg aagaattagc agatgttgtg tatgcgtttt
    19261 ccgctttgct tcgaaacaat acgaatcaag agaaaacgat cactttaaaa gaagaactgg
    19321 acttttgcga aaaatatgtc tatttgtatc aaatgcgtta tcctaatcga gtagcctatc
    19381 attttatgat cgatcctgat ttggaaaaga tcgaagtacc taaatttgtg atccagccat
    19441 tagttgaaaa ttattttaaa cacggtattg attttactcg attcgataat gcgctaagtg
    19501 tcaaagtctt gcaggaaggc aaacgggtaa ggatcatcat caaagataat ggaaaaggga
    19561 tgactgaaaa acggctaaaa cagattgaag aaaaactgtc tcatcctaaa gtggaacttc
    19621 acggttctat cggtctgcaa aacgtgaatg aacgtttacg tgccagcttc ggcagcagtt
    19681 attatatgtc gcttgagaat aatgagacag gtggactgac cgtttctatt acattcaagg
    19741 agggatgagc gtgtatcaag tgttattggt agatgatgaa tacatgattt tgaatgggtt
    19801 aaaaaagata attgattggc aaagtttagg ctttcaaata gtagcaacag cagagaatgc
    19861 caaagaagga ctagctgtac ttgaacagcg acagattgat ttagtagtaa cggatgtgac
    19921 aatgccagaa ataaatggac tggaatttat tgaagcggct caaaaagaac gtcataattt
    19981 tgaatttatg attttatcag gataccaaga attcgattat ttgaaaggag gtatgcaatt
    20041 aggcgccgtg aattatttga tgaaacccgt gaataagttc gaattggttg aaagcctcaa
    20101 gaaaatcaaa acacggttag atcagcaaaa tgaacaaaaa aatcaacaag aaatctatca
    20161 agaactgtta ttcagtcaat ggttgaatga agaattggat gaaataagtg aagaagaaat
    20221 aataggacaa ataagtgaga agcagcatag gatagtattg attcaactgg caagaactca
    20281 tgatactctt atcaatagat ggttgcaaga acggcaacaa atcttttact atcaacgaaa
    20341 ttacggagac cgtgtattga tcacgttgtt gttggaggca gatgaagttg atggcttctg
    20401 ttgttttgtt caagaaaact ttcctgatca ggaatggctg atcagtatcg gggaagagac
    20461 agattctttg gacaaaatcc ctgaaacatt ccaacaagcg aaagacaatc tacagttgca
    20521 tcaattttat ggagataaag acgagcatgt tttttacgca gtacaagcag aaacaaaaga
    20581 tcaaaccatc gatttttcaa gtttcagacg cgtgctgcaa aataaacaat tggaagtcgc
    20641 tcaaaaaatg atcactgatt tttttgaaca gtttcagtta gcagccatga tgccggaaga
    20701 tatacgatat tccagttttt tactgtttat ggagattcaa cgggaattga ttgatctgga
    20761 agatgaggaa tatttacaag gaatcgaaaa aatccatcag gcaaaaacgg tgcaagaact
    20821 tcagcagcta cttctgtcat tcatcaaaaa gcatcagaga cagaaaaagt acagtgacaa
    20881 tgtggaaaaa gtaatcgtaa tcctgcacca gcattatcaa gaaccactta cactcaaaga
    20941 agtgtcagaa aacctgcatt taaatgtcat gtatctagga cagctgttca aaaaagaaac
    21001 gaaaaaaagt ttttcagctt atttgaacca tttacgtatg gaaaaagcga aacaactgct
    21061 tttgcacagt aatcaaaaca tcaatgagat agcaagtgag attggctaca acaacaccac
    21121 gtatttctct aaattattca agaaaatcgt cggcagatcc cctaaagagt accgagaaaa
    21181 cagtggagaa tcataaaaaa aaagccaatg taatgaaata acttataaaa aattgtctag
    21241 aaatctaatt ttgggctgtt cttattactt gaggcaaggc agctttttca tgacctctcg
    21301 ataaacggag ttcaaaagcc agtttctcgg tattaagcca aatttatgca aaaatgtgga
    21361 aagccatttt cacaaaattt ttcttaatac tcgaaactaa acagcttttt cacgacctct
    21421 ccactaaatg gtgttcaatc agctgaccct cggtattagc tcaaaaaatg gcaaaatatg
    21481 aggaactatt ttgccatttg tctctctaat actcaggtca gaacgctgat ttcacaacct
    21541 ctcaataaac ggtgttcaaa agcttgcatc tgcggtaata agaccaacca aacgaaaaat
    21601 atgaggatct atttttgctt ggctgttctt attacttgat gcaggacagc tttttcacaa
    21661 cctcttgtta attatagttt gataaggaaa aaggcaaatc ttttgcttga tatttcttag
    21721 ggtgagggat gatccctaat tggtaagaga tcgtgccgcc tttcagcaaa tcttgatggg
    21781 taaaatataa tttcgtatat tctctgtcca tccgtttgat tttatggata aattgttgct
    21841 gcggccgatt aggcgttgct tcaatcgtca attcctttcc atttgacaaa agcaaaacag
    21901 ccttgtcaat taatggcata ccgataacat attcaccggt tccaggcgtg acaggataaa
    21961 atcccagact attgaagata taccaagcgg ccatacttcc attgtcctca tctccagggt
    22021 aacccattgg agaatcgtcg aaggtctgag tcatcaactg tttaagcagt ggctgtgcca
    22081 tttcaggttg tcctatataa ctgaacaagt aaggatagtg aaaacttggc tggtttgaaa
    22141 tagctaattg tccaaattct atcgcggcca tctcactcat ttcgtggatc tcaaaaccat
    22201 atcctcctgg gtcaaacgtt gggggctgat tgcacagctc aatgagtttt tctttatatc
    22261 tctcactgcc accatatttt ccgatcagtc ctgaaaaatc gtgataaaca gcaaagctgc
    22321 tttgccaagc acttccttct gcataatctt gtccccaacg attagctgaa aatggttctc
    22381 tgaacttgcc atctttatct tttgaacgca taaatcctga ctcatagtca aagatatttt
    22441 gatagttcaa tgattgctgc tgatatttct tcgtcatttc ctcttcttct agtaccttgg
    22501 caacttggct aatacaaaaa tcgctataag catagtctaa tgtgtgattg actgattcgt
    22561 ggtagtgatt aggaacatag ccatatgtca agtaatcttc tgttccttgg cgtccataat
    22621 ttggatgttt gctttgaacc gtagcacctt tttccattgc cgttagaaat tcaggcatca
    22681 agtctcgtcg gatatctttt acagcagcat ctgcaatgac cgcatcgatc aatgtcccag
    22741 gcataagtcc acgttcatca ggagacagcc attttggcaa atagccactt tctctatagc
    22801 tgttcaaaaa accttccagc atttcttcgt atttttctac agcaatcaaa gaataaagag
    22861 gataaaccgt tttatacgta tcccaaaacc cattatttgt atagagaaca ccaggtttta
    22921 tagatcgact agtcgtatca tagtggattt tttgcccact aggatcaatt tcataaaatg
    22981 tttgtggaaa taaaaacacc cgatataaat tatgataaaa cgtccgcaat tgttgttgat
    23041 catggtgtgt gagctgtata cgatcaaaat aggactgcca ttgttcttga ctgtgagcaa
    23101 ggtaagtctc tttgctttgg ttttgttcta gttccaggtt ataagctgct tgttccgagc
    23161 tgataaaaga tgtcccaaat cggatagttt gtttttttgt ctgttcaaaa tacaacggga
    23221 tcgagtcgct atttttgttg gaaacagcta actcatcaat tgttaaagga tattcaaatc
    23281 tcaatataaa ataaaaagaa aaatcaggat cttctgaacc agcaaaatgt gtgatttttc
    23341 cttccactgt gtaaggatct ataacaaaga gctgatggcg tcccggaaag gataaaagta
    23401 aaccgctgtc atttttgctg taatcaatag ataagattcc gccatacatg ctaggtatca
    23461 atgtagaaca gatgccataa cgtaattgac agatcgacag atgagtcggg caaaatatac
    23521 tttcttctgg gcggtaagaa ctttgagcat ggaaaagggt gttctcctgt agttttccat
    23581 tgatcggcgt aaacagcata tgactgaaat cacccatcca aggacttggt tgatgggtaa
    23641 gacggtagcc ttgaaaaacg cggtcatcag gatgaaacca ccagctgccg ttttgatccg
    23701 tagtttgcgg tgcaaaataa ttcatcccaa aaggaacgcc agtataaggc tggcagttcc
    23761 cattagagaa atttggctga ttcgctgttg catgtctagt atctatttga ccgatattca
    23821 ttttatttct cctttgttga ttgtcttttg atgaatgaaa ctggaaattt actatcggat
    23881 ggtcgatctt ttgtctctaa ccaagtgacc aaagcatctc ccgcaagctt acctaactgt
    23941 tcaaaatctt gtgcgatggt tgtcagtggc gggtcaacaa gagctgctgc ttggatatca
    24001 tcaaatccga taattgaaaa atcttcaggg atatgataac catgctgtct caagagattc
    24061 atggtctgga tagcgacaac atcgttttca caaacaaaag cagttacttc atacttagtg
    24121 atataagaaa gcaattcatc taatgtcgcg cttttgtcat ccagtgaagt gtggaaagtc
    24181 aaaccagctt tgtccaatgc ttcaaggtaa ccaaggtaac gctgtcgaac ggattgtgga
    24241 tgagtctgcg taccaaacaa ataagcgatt tttgaatgtc cctgttcgat caaataagag
    24301 gcagcaagcg caccgccttg gaaattatcg gaaagaacgg taggaaaagg taactcatag
    24361 atttttttat ctaatatgac gacagggaat tctttcaatg aaagctcaaa aagtaagtca
    24421 agatgttgtt ctgtatcaag agcataataa atcaatccgt caaattcatt gattagctct
    24481 tttgctgttt tattttgtag aaagtcaagc gtcgtcatca tgacatcaat ctgtttatct
    24541 tgcatcacag ggttcaatcc cttgctaaaa tcaccaacag acaaatcagc gacatatgga
    24601 agaagaaaca gaatccgtcg tgtttttgta ggagaagcaa gaatctgttc cggagaagcg
    24661 gatttaacga aactgccttt cccgcgaacg cgataaataa gtcctaattg ctctaattca
    24721 gtcaatgcac gtttggaagt gattctgctt actttatagg tacgtgaaag ttctttttca
    24781 gttggtagtt ggctgtctac aggtaattca ccagttaaaa tagccgtttg caaatcatta
    24841 aatattgtct ggtacaatgg ttgagtcata taaacacctc ttaatgatat atcatattca
    24901 aataatacca taatggatga aaaagtaaat aaaaagatat tttttgaaag cgtagacata
    24961 attggctgta tgaagtataa tctttaaaga tatatcaaat agaaagaagg ttttattagt
    25021 ggtttataaa gatataccaa aatcggtgca gaaatttatg gaagatatca cacaaaaatg
    25081 tggggatatc catgcggact gggcaaagaa ttttacagca gcatttgcca atactctgtt
    25141 gacaacagtc aaaaagcaaa atgacggaac caccttttta ttgacgggag acattccagc
    25201 gatgtggtta agagactcta ctgcacaagt tcgtccttat ttagtgattg caaaagaaga
    25261 tgaggaatta gctgacatga tcagcgggtt agtcaaaaag caattttttt atatcaatat
    25321 cgatccatat gcgaatgcct tcaacgaaga agctaacggt gctggccacc aaacagatca
    25381 tacaaaaatg aacgattgga tctgggaaag aaaatatgaa attgattctt tatgctaccc
    25441 aatacagttg gcctatcttc tttacaaaaa tacaggaaaa actgatcaat tcaatcaatc
    25501 ttttattgaa ggtatcaaaa aaatcttgga cgtgttcaaa acagagcaag atcatgaaca
    25561 ctctccttat acatttgtac gagacacgac aagaaaagaa gatacgctga tcaatgacgg
    25621 gcgaggtgca aaaacagctt ttacaggaat gacatggtct ggtttccgtc ctagcgatga
    25681 tgcttgccgt tatggatatc tggtaccatc caatatgttt gcggtggtcg tgttaggtta
    25741 tgtggaagaa atttttcaaa cgatactcga tgataaagaa attgtacagc aaacacagaa
    25801 attgaagaaa gagatccaag aggggattca gaatcacgga cgaacggtta atcaaaaagg
    25861 gcaaacgatt tatgcatatg aagtagatgg aatgggaaac gccacagtca tggatgacag
    25921 taatgtgccc aatctgatcg ccgcacctta cttgggatat tgttctgaac aagaggaaga
    25981 ttatctgcaa acaagaagaa cattgttgag taaagaaaat ccatatttct atgaaggaaa
    26041 gtacgcaaaa ggaattggat cctcccatac gccagaaaaa tacgtttggc cgattgcatt
    26101 agctatggaa ggaatgacaa cgtcagacaa atctgaaaaa gagcggatat tgaatttact
    26161 tgtagcaact gacgcaggaa cacaccttat gcacgaagga ttcgatgtga acaatcctga
    26221 aaattatacg agagaatggt tttcttgggc aaatatgatg ttttgcgaat tagtcatgga
    26281 ttactttgat attagagtag aaaagtagga ggtatcgtaa atgaaaaaga aagtatatat
    26341 catttctcat agccactggg atcgtgaatg gtacatggct tacgaacagc atcacatgcg
    26401 actgattgaa ttgatagacg atctactaga gctatttgaa gttgatccgt ccttcaacag
    26461 ttttcatttg gatgggcaaa cgattatttt agatgactat cttcaagtaa ggccagaaaa
    26521 aagacaggca atccaacaag caatcaatga aggaaaattg agaattggac cattttatat
    26581 cttgcaagat gattttctta tcagctcgga atcgaacgtg agaaatatgc tgattggcat
    26641 ggaagaaagc cgtaaatggg gaacccctgt catgttaggc tattttcccg atacatttgg
    26701 aaatatggga cagacgcctc aattaatgaa acaagctggt atttcagcag cagcgtttgg
    26761 ccgtggtgta aaaccaattg gctttgataa tcaagttttg gaagcagaaa actattcttc
    26821 ccaatactca gagatgtggt ggaaaggccc tgatcaaaca gcaatctttg gtctgctatt
    26881 tgccaattgg tatagcaacg ggaatgagat tccagtagaa aaagaagcag ctcttgcctt
    26941 ttggaagcaa aaattagcgg atgcagaaca atatgcctct acgaaccact tattgatgat
    27001 gaatggtgtt gatcatcaac cggtacaaaa agatatatca aaagcaatcc atctcgcaaa
    27061 tgaactgttt ccagattacg agtttattca ttctaatttt actgactatc tggaagcagt
    27121 tcaaaaagat gtgccagaag acttaggctc agtagaagga gaattgacaa gtcaagaaac
    27181 ggatggctgg tatactttag ccaatacagc atctgctcgg gtttacttaa aacaatggaa
    27241 taccaaggtc cagcgacagc tagaaaatat tacagaacca cttgcgacga tggcttatga
    27301 agttagtgga aactatcccc atgatcaatt agattatgct tggaagacat taatgcaaaa
    27361 tcatcctcac gacagtattt gcggttgttc agtcgattct gtccatcggg aaatgatacc
    27421 tcgttttgaa aaagcagatg aagttggaaa gtatcttgca caagattcct tagaacagct
    27481 gaccgcagca atcgatacga ccggattccc aaaagacagc tttccatttg tcattgtaaa
    27541 tactgcagga atggataaaa ctggtgaagc agaaataacc atcgaattag aaagaaaaag
    27601 attcgctgaa ggaatacctg aacaactata tcaagagtta gaaaatttgc ctaaacgtaa
    27661 gtatcatgta gaaacaaaaa gtggggccac tataccagct attttatctg aagaaactgt
    27721 ccaatttggt tatgatttgc cgaaagaccg tttccgtgtg ccatatatgg caagaatgat
    27781 caaagtgact ttaccattag aaaacatgcc agcattttct tgggaaacat tcgcgcttgt
    27841 agaaggggaa gcgaaagcag aagaaaagga aacaatgatt catcagagtg gacgaatcat
    27901 cgaaaacggc cctctacatt tgacgattga aaaaaatggt accattacaa tggaagatcg
    27961 caaaaacaaa cgaaagttga ataatctgca tatttttgaa gatatcggcg atataggaaa
    28021 tgagtatatc tttaaacaac ctttctgtga tcagccaatc ctatccagta acaaagaaaa
    28081 ctctgaagta aaagtattag tagatacacc ggaaatagca aaaataagta ttctacagga
    28141 aatggaaatc cctgtttctg cagacgagcg tttagaaaaa gaacagcaga tggttgtgga
    28201 atttcgttat cgaaaagcag aacgatccaa agaaaaacga atccttcaaa taaaaacaat
    28261 catgacaatc agaaaagata gtaaaaaaat cgactttgaa acgactctcg acaatcagat
    28321 gaaagatcat cgcttacgtg tcttgtttcc tacaaagtta catgtggaac atcacgaagc
    28381 agatagtatt tttgaagtgg tgaagcgccc aaaccatgtg tctaaaagtt gggaaaaccc
    28441 cacgaatccg caacatcagc aagcatttgt caatattcat gatgaagagt acggtgtaac
    28501 agtcggaaac tttggtttga atgaatatga agtaacagaa gacggacaaa tcgcagtgac
    28561 gctacttcgc agtgtgggag aactaggcga ttggggatat tttccaacac cagaagcaca
    28621 gtgtctaggt gagcatcggt tcaattacag cattgaacta catggaccag aagaaaaatt
    28681 ctctacttat ttgcatgcat acgcagcaca gattcctttt tccactcaac aaatcaaaca
    28741 tcatgaagga acattgattt caaaacaaca atatttaacg ataaaaagtg aaacgtttgc
    28801 aattacagct ttgaaacgca gcaagtttag tgataaagta gtagtaagag gtttcaatat
    28861 gtctagtcat ttagaaaaat tggaaataac taaagacaat ggaaaaactg tcatattgaa
    28921 tctgcttgaa gaaccaacga agcaagcggt tgtcccaata atccaacctt atgagattcg
    28981 gacaatcgga ttcgaggagg aaaacgaatg tatggcggaa tagaagcagg cggaacaaaa
    29041 tttgtgtgtg cggtttcaga tggtggagaa attttagaaa aattaagtat ccctaccaca
    29101 acaccagaag aaacattgga tcaggtattt gaattttttg atcgttatga attgaaggga
    29161 atcgggattg gctcattcgg cccgattggt atcgacaaaa caaaagataa ttacggatac
    29221 gttttggcaa ctcccaaaaa agggtgggca caattcgatt ttcttggcac aatcaaggaa
    29281 cgctacaata ttcctgctgc ttggacaacg gatgtcaatg ctgctgcata tggggaattg
    29341 aagcaaggag cagcacaagg aaaaaatagt tgtatttacc ttaccgtggg aacaggaatc
    29401 ggtgcaggtg tcgtgatcaa tgaagaaatt ttttcaggga tcgcacatcc tgaaatggga
    29461 catatttggg tgaaacgcca tccagatgac cattatgaag gtacttgtcc ttatcataaa
    29521 gattgtttag aaggattagc agcaggaccg tctattgagg cacgcacagg gatcaaaggg
    29581 caagatctgc cgcaagatca tcctgtttgg gctattcagg cttattatat tgctcaagca
    29641 ctgatcaact atacgttgac gttagcacct gaaaagatta ttttaggcgg tggggtaatg
    29701 aatcaggatc atctccttca aaaaatccgt cagcaatttg ttgaattgat gggtggttat
    29761 atggaaacac ctcaagtaag tgaatatatc gttcgttggg gactgccgaa tgaaagtggg
    29821 attatcggta gtttgctgtt agcagaacac gaacatcaaa agtaagcaga caaattacac
    29881 aaaaagaaca gagtcttatc attatctgct gataagactc tgttcttttt tatttctatt
    29941 cccataatcc aggtaaagct ttaccgacta ttttttcttg agtaaatgga tggatcatgt
    30001 gcagttctaa tgcatggagc atcagtcgtt cagctgttct attttggtag agagggtctc
    30061 caacgatcgg atgtccctta tgagctaaat gaactctgat ctggtgtgta cgtccggttt
    30121 ccaaaacaca atagacttgt gtttgttcag aaagtacttt gttgacagtg acatgtgtca
    30181 aggcgctctg accattttta tcatctacga ccctttttct ccgatcatgg cgatctcgtc
    30241 caattttatt ggtgatggtc atatctttgg caatttctcc ccatacgatg gcttgatatc
    30301 tccgatagat cattttttgt tccaacattc ttccaagtat cggcaagaca aatggatttt
    30361 ttgcaaataa aacggcaccg cttgtttctt tgtccaagcg gtggacaacg taaggtcgtt
    30421 gctgtttagt gtcgagataa gcagctaaat gattgagtaa ggtactgttt tctgtcggtt
    30481 catttggatg agtcttcatt cctgcaggct tatccactat aatcaaatgc tcatcttcat
    30541 ataaaacacg gatgtgcttc gcatctccta attgaacttc ttgataatta taatctgttt
    30601 cttcgaataa caatgtgatc tggtcattgc cctttacttc atgatggaac aaagcaggtt
    30661 gttgattgat ccaaacgttt ttacgtatac gcaaaaagtg tcgaaccttt ctaggaacta
    30721 accattcctt ttcaagcaag tcgcgaattg ttgtttcagg atggttcata ggtaaagtga
    30781 tcgtgatttt cacaagtgta ctcctttcag tgcaattgca gactaattgt accattttta
    30841 aaacatattt aagaaaaaac ttacattttt ctgttcattc ttatgttact ctacttgcac
    30901 taacgtaaaa aaacatattg aactacaact taagcaggaa gaaaacactc tttcactatg
    30961 gtaaaataag acgattgaat caaatagaca ggagaagaag caaatggatt ttcaaagcat
    31021 tttagaaaag ataaaagctg ctttgatcag tttttggcgt tggatcagac catatctcgg
    31081 acaattccat cgatggcgaa agcgcatctg gaaaaaatat catgtgaaca aattgatttt
    31141 gctgattggt ttgatctgtg tcttagtgac aagtatctac ctctttattt tagcaaaaca
    31201 agcaaatgtc gaaacgttaa aatcaggatt aagccaatcg acagtcattt atgataagaa
    31261 aaacgaagaa gctggcacac tgtacgccca aaaaggaaca tatgtagaat taaacgcgat
    31321 ttctccctat atccaagatg cagtaatctc gacagaagat aggaattttt acgagcatca
    31381 cgggtttgat atcaaaggga ttgcccgtgc agcagtccga atggtcttgt ctggcggaac
    31441 atcagggggc ggaggaagta cgatcactca gcagcttgcc aaaaatgcgt atctgacatt
    31501 agaccaaacg tttgatcgaa aagcgaagga attatttttg gcaatcgaga tcgaaaagaa
    31561 gtacagcaaa gaagaaatct tgaccatgta tcttaacaat gcctattttg gcaacggggt
    31621 atggggtgtc caagacgctt ccagaaagta ttttggagta gatgcaacga atgttacgct
    31681 gtctgaggct gctactttgg caggaatgct gaaaggtcct ggtatttata atccgatcga
    31741 tcacccaaaa aatgcgaatg atcggaaaaa cacagtacta agtgtaatgg aagaaaacgg
    31801 aaaaatcaca aaagaacaag aacaagcaga aagccagaca gatatcagcg cgtatcttaa
    31861 tgacacatac gataattcag attctggtta tcgttatcct tattattttg atgcagtgat
    31921 cgatgaagca gttaacgagt atggtcttga tgaagaagat gtcatgaata aaggctataa
    31981 aatctataca gctttagatc aggattatca aaagcaatta gaagctactt atcaaaacag
    32041 tgcattattc ccagcaaatg cttcagatgg tgccatggtc caatctgctt cagtagcttt
    32101 agatccgaat acaggtggtg tacaagcact agtaggacga agaggagatc atgtctttag
    32161 aggattcagc tttgctacac agatgcgtcg ttcaccagga tcaacgatca aaccattaag
    32221 cgtatataca ccagcactgg aagctggata caagccttcc agtatcttga aagacgaacc
    32281 gcaaagttat tacgatgcgc ataattttga cgggacatac caaggagaag taccgatgta
    32341 tcaagctgtt gcacaaagtt tgaatttgcc tgctgtatgg cttttgcatg agatcggttt
    32401 acaaaaagga tatgataaag cagaagaatt cggcctgcct ttagcaaaat ctgataagta
    32461 ttatggctta gcccttggtg gactggaaaa aggagtatct ccattgatca tggcgggtgc
    32521 ttacagtgca tttgccaatg atggtcagat gtatacgccg catcttatca cgaaaatcgt
    32581 tgattcgact ggagcggtga tcgtcgataa cacaaacaaa aaaccaaaac aggtcatatc
    32641 aaaggaaaca gccgatgaaa tgaccagcat gcttcttggt acattttcaa atggaacagc
    32701 ggctgctgcg aatcctgcag gttatacgat agcagggaaa acaggaacca cagaaactaa
    32761 tttcgatgcc acaaaagcaa atgaccaatg gatgatcggt tacacgccag acgtagtgat
    32821 ttcgacatgg atgggttacg aagaatccag caagctgcac tatttggaag ggacaagtgg
    32881 aaatgttgtc gggaaagtct tcaaatcagc ggcagaaggc atccttccgt atacttcaaa
    32941 aacaggattt agtgtagcag atgcctatgc cacaggagga caagtggtag ctgcagatca
    33001 agttggaaac acaggaaatt ctaatggaga gtctggaaat tggcaagata acttgaatca
    33061 atatggtgaa caagcaaaag aagggctgaa aaacttcggc gatatggtga aagaaggcgt
    33121 tcagggaatt ggtgaagcgg ctaaagacct ctggcggaaa tatcaaggag agtagcccct
    33181 ttgaaaacga ataaccccat gttacaatag agagtaacta ctaaaagaaa agagggcata
    33241 acatgtcaaa catctacgat agcgcgaatc aaatcgaacg tgagatccgt gaattaccag
    33301 aattcaaagc gttgaaagaa gcgtacgaga aagtacaagc aaacgaagaa gcacacaaac
    33361 tgttcaaaga cttccaagcg atgcaaatcg aattacaaga aaaacaaatg agtggacaag
    33421 agttcagcga cgaagatgca atgaaagcac aagaaatggc tgtgaaaatc caatcagaag
    33481 aagtaatcaa tgacttgatg caaaaagagc aaggcttcag tacaatcatc aatgacttga
    33541 accgtatcat catgacacca gttcgcgacc tttacagcga ataaaactat tttatgaaac
    33601 aacagagggt gtgaaagaga cgttcggcct tgagcgatga caaaattgct tcttattgcc
    33661 gataggctgt ctcttgaaca ccatttacca agaggtcgtg agcctaccgt ttaactctga
    33721 gttacaagga acaatttcaa aaaacagctt ctcatgtttg atgactattg tgacttgtga
    33781 ccgaggagtt ggcaggagaa caccgtttat tcagaaatag gagctacgac aaaagtcttg
    33841 tcatagctcc tattttttgt cattcatttt tcaagcggta gaaatagcct ttttgagcta
    33901 acagtttttc gtaagtacct atttcaacga tttttccttc atcgatcaca acgattttat
    33961 ctgcctcttt gatcgttgaa agccgatgag ccacaataaa agtagtgggt gtttctgtca
    34021 ggtaattcag ggcttgctgg atttttttct ctgactggtt atctaaagct gaggttgctt
    34081 catctagcaa aatgattttt ggctgacgta tcaacgctcg tgcaatggag atacattgct
    34141 tttggccacc agacagcttg ttgccatgtt cgcctactaa ggtatccaga ccatcaggaa
    34201 gctggtcaat cagtgaagaa agttgcgcag cttcgatgac ttcatctaaa cgttcttttg
    34261 atacgttttt caagccataa gtgatgttct ctttgatcga agcggagaac aacaaagtgg
    34321 tttgaggaac aacggctaaa taatttcgca cacttcgcat atccagttca tccaaaggct
    34381 gatcatctag aaaaattttt cctgaagtcg gctggataaa tccaatcaat aagttaagga
    34441 gtgtagattt tccagagcca gatggcccaa caaaagcaat tgtttctcca gctttcacct
    34501 ctagagaaaa atgatcgata atcggtttga gtgagtccgg ataaagaaaa gaaacatcct
    34561 caaaacgaaa atttccatcc aaatgttgga tttttttctt accgtgataa gtttctacat
    34621 cgccagcaat caacagttcg ccaatagaag tgatagattc catgcctttt gaaatcgtag
    34681 gaatcagcgt gatcattcca gaaacggaat tgacgatcgt cgtgaaatac gtctgataca
    34741 tcacgacatc gccgggttgg atgcgccctt gtaaagctaa tatcccagtg aaactcaaac
    34801 aaatcagctg aaatatctga aaactagccc agctgactga tccgaaaaca gattgcagga
    34861 tatctaagtg gaatcctttt tcatagattt gagtaaaatg cttatttaag cgagttgttt
    34921 cgtgtttttc taacccatga gctcgagcaa tcggtgctaa ttcgatcact tcgatcactt
    34981 ttgcagaagt ctcttccatt tcttgcctga agtctgagtt ggactgtctg atccttttac
    35041 ggaaaaagag agtaacgaat gcggcgagag gaacagtcaa taagaaaaac atgaaaacaa
    35101 caggactttt ataaagcgtg atacctaaag ctacgaataa attgacagcg atatttaatc
    35161 cgctgacaaa tacttgagag gacaacgttt ggatagcttc tacatcacgg atgatctttg
    35221 actggattcg tccagattgc aattcttttt gataaggaat agatagttct tggattttct
    35281 tgataagggt cgctcttagt ccagcttcta cttgacggat cgaagtgcta tggtatttta
    35341 catgaaaata attcgtcaat atattttgac caatcagaca agccatcaaa aaagcgttga
    35401 aataaatggc ctgcaactga gaagaatctt tcgatgaagc tgcattgatt acattggcaa
    35461 tagcgatcgg cattaaccaa gatggaagat gtttgataat aaaaaagagt cctgacatgg
    35521 caaaacgcca ataatttccc tgataaagat gcagcaatgt ctgaaaagca tttgcatgat
    35581 atttttgata acttttctgt attcgttcct ccataatctt ctccttaaca atcttggtaa
    35641 ataaactgca agtgttctat tgcttcagga acataaatct caggagtagc ttcaagagtg
    35701 gcgtacatta gaggacgctc atatttgata taatgcagta ccgggcggaa atctaaacag
    35761 cccttgccaa caggtaccat gcggatcttt ccattttcca tgatatagtc tttgagatga
    35821 agcgctgtaa tataaccatg taaattgtcc aaggcacctc ggatcacttt ttcctgatca
    35881 gcatgatttt ctttatgcat caaattcgca caatctaaaa tgatttttaa atttggtgaa
    35941 gctacttcat cgattaaacg tttagctaac tgatagttat agattggatg attgatccct
    36001 gcttcaacag caacagttac gccaaaattt tctgcatgag cgactaattc aatgatagaa
    36061 tttctggcga tctgataagc ttcttcagta aaattttctt ttgtgtaacc gacagagaca
    36121 ctaccggttt ccgtagcaat catcttggct tgataggcag agcacagagc aatttgctgt
    36181 ttgaaagttg ccaatgcttg tgcacgaact tcttgatttt tgctggatag gttgatatag
    36241 catcctaaaa tggaaagttc gatattgttt ttttggaagt attcaccaaa ataggcagca
    36301 ctcccaagtg tcatgtcagt taatttaagt tgttcaggaa atgctttttg tggtgcaaat
    36361 tggatatggg acaagtgaag ctgtgatact ttttgaacga tttcttcacg atttcgaaca
    36421 tctaaatcgt gggcacggat gcctaaattt aatggaaaca tctcaaactc ctttttgtaa
    36481 ataattagca agaggcagac gggattcttt tatcaattca acaattattc gggcaacttt
    36541 atcagcgcct tctggactaa agtgggtatt gtcttttagt ccttctgggt aatttttaca
    36601 agtatcaggc ataagatgca ggtagaattt ttttgtctct tcttttgaga aggtctggaa
    36661 caattcttgt gatcttgaga acacatctaa aagaggaata tggtgtttct cagcaaatgc
    36721 acgcatcgct tttggatagt ctccaagtat atctggattc aatgttccgt tttctaagta
    36781 atctcgtcgc gtcacagatg tcagtaagac catttggacg ttcgcttttt ttgcgcattc
    36841 aaaaaatatc tgcagatttt ttaaatagct accgaaggga agcgtacctc tttcttcttg
    36901 gattttctgg tcgttatgtc caaattgtac aaataagaaa tcattcggct gaaactgtga
    36961 agctagacgg gctaaccttc cttcctggat aaatgatttg gtgctgcgtc cattctttgc
    37021 ttggttattg atctggatct cgggtgaaaa ataagcagag attttttctc cccaacctgt
    37081 ctcgggacgc ttgttttcat ctttttctgc cgcagtagaa tcaccggcaa tatggatagt
    37141 aggcatgtta tctcttcttt cataaaggtt tataggcaat gaagcagaac agcaagagaa
    37201 gaagacggag caa
//
LOCUS       DACBYO010000020        37005 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.020, whole genome shotgun sequence.
ACCESSION   DACBYO010000020 DACBYO010000000
VERSION     DACBYO010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.020"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(59..187)
                     /locus_tag="IVD26_000979"
     CDS             complement(59..187)
                     /locus_tag="IVD26_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP6078974.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="IVD26_000980"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="IVD26_000980"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP6078975.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="IVD26_000981"
     CDS             complement(1674..2729)
                     /locus_tag="IVD26_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP6078976.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="IVD26_000982"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="IVD26_000982"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAP6078977.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="IVD26_000983"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="IVD26_000983"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAP6078978.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="IVD26_000984"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="IVD26_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAP6078979.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="IVD26_000985"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="IVD26_000985"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAP6078980.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="IVD26_000986"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="IVD26_000986"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAP6078981.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="IVD26_000987"
     CDS             10491..12050
                     /locus_tag="IVD26_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAP6078982.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="IVD26_000988"
     CDS             complement(12161..14092)
                     /locus_tag="IVD26_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP6078983.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="IVD26_000989"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="IVD26_000989"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAP6078984.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="IVD26_000990"
     CDS             complement(15021..15773)
                     /locus_tag="IVD26_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP6078985.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="IVD26_000991"
     CDS             complement(15932..16141)
                     /locus_tag="IVD26_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078986.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="IVD26_000992"
     CDS             complement(16152..17480)
                     /locus_tag="IVD26_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078987.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            complement(17845..18432)
                     /locus_tag="IVD26_000993"
     CDS             complement(17845..18432)
                     /locus_tag="IVD26_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAP6078988.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="IVD26_000994"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="IVD26_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAP6078989.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="IVD26_000995"
     CDS             complement(20012..21301)
                     /locus_tag="IVD26_000995"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAP6078990.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="IVD26_000996"
     CDS             complement(21455..22387)
                     /locus_tag="IVD26_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078991.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="IVD26_000997"
     CDS             complement(22544..23203)
                     /locus_tag="IVD26_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAP6078992.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="IVD26_000998"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="IVD26_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAP6078993.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGASGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="IVD26_000999"
     CDS             complement(24244..24534)
                     /locus_tag="IVD26_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078994.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="IVD26_001000"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="IVD26_001000"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAP6078995.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="IVD26_001001"
     CDS             complement(26821..28176)
                     /locus_tag="IVD26_001001"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAP6078996.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="IVD26_001002"
     CDS             complement(28200..29369)
                     /locus_tag="IVD26_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6078997.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="IVD26_001003"
     CDS             complement(29366..30253)
                     /locus_tag="IVD26_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAP6078998.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="IVD26_001004"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="IVD26_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAP6078999.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="IVD26_001005"
     CDS             34320..34841
                     /locus_tag="IVD26_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAP6079000.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="IVD26_001006"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="IVD26_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="IVD26_001007"
     CDS             complement(36284..36940)
                     /locus_tag="IVD26_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079001.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
BASE COUNT        10084 a         8035 c         6532 g        12354 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagcc cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttca
//
LOCUS       DACBYO010000021        36205 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.021, whole genome shotgun sequence.
ACCESSION   DACBYO010000021 DACBYO010000000
VERSION     DACBYO010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.021"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..377
                     /locus_tag="IVD26_001008"
     CDS             <1..377
                     /locus_tag="IVD26_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP6079002.1"
                     /translation="IEQPNLDRIKTARLEKKDKIVKNIASLDSDYFTELSNLYFSMTS
                     LLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKALNLNIDERKELESELFGN
                     LTQVQVNNLKREITARLISKLQ"
     gene            432..1598
                     /locus_tag="IVD26_001009"
     CDS             432..1598
                     /locus_tag="IVD26_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6079003.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            2015..5242
                     /gene="fss3"
                     /locus_tag="IVD26_001010"
     CDS             2015..5242
                     /gene="fss3"
                     /locus_tag="IVD26_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAP6079004.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            5354..5668
                     /locus_tag="IVD26_001011"
     CDS             5354..5668
                     /locus_tag="IVD26_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP6079005.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            5681..6055
                     /locus_tag="IVD26_001012"
     CDS             5681..6055
                     /locus_tag="IVD26_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP6079006.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            6065..6409
                     /locus_tag="IVD26_001013"
     CDS             6065..6409
                     /locus_tag="IVD26_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAP6079007.1"
                     /translation="MEINVEHILDCLDQFGKGELTEEQLTNALTYDEKMFLIMHQGLL
                     EVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFLKQL
                     VETKQLPVVVND"
     gene            6478..7494
                     /locus_tag="IVD26_001014"
     CDS             6478..7494
                     /locus_tag="IVD26_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAP6079008.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            8088..9962
                     /gene="ltrA"
                     /locus_tag="IVD26_001015"
     CDS             8088..9962
                     /gene="ltrA"
                     /locus_tag="IVD26_001015"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP6079009.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            10088..10444
                     /locus_tag="IVD26_001016"
     CDS             10088..10444
                     /locus_tag="IVD26_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAP6079010.1"
                     /translation="MILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRV
                     ALGRMSELGYSMMFGEVDKNFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREIS
                     NIVGLTVHTERENNSV"
     gene            10489..11631
                     /gene="dcm"
                     /locus_tag="IVD26_001017"
     CDS             10489..11631
                     /gene="dcm"
                     /locus_tag="IVD26_001017"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAP6079011.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDSVAPTLTGD
                     EGIKIALPVKDGISVAGMLSGNFEQGNRIYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKGVKAYDL"
     gene            11621..11910
                     /locus_tag="IVD26_001018"
                     /pseudo
     CDS             11621..11910
                     /locus_tag="IVD26_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395166.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12166..13350
                     /locus_tag="IVD26_001019"
     CDS             12166..13350
                     /locus_tag="IVD26_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP6079012.1"
                     /translation="MAQRNLDYRLLKERRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     IASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            13365..13460
                     /locus_tag="IVD26_001020"
     CDS             13365..13460
                     /locus_tag="IVD26_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAP6079013.1"
                     /translation="MEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
     gene            14230..16140
                     /gene="ltrA"
                     /locus_tag="IVD26_001021"
     CDS             14230..16140
                     /gene="ltrA"
                     /locus_tag="IVD26_001021"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP6079014.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            16244..16468
                     /locus_tag="IVD26_001022"
     CDS             16244..16468
                     /locus_tag="IVD26_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079015.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            16481..16984
                     /locus_tag="IVD26_001023"
     CDS             16481..16984
                     /locus_tag="IVD26_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP6079016.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            17111..18148
                     /locus_tag="IVD26_001024"
     CDS             17111..18148
                     /locus_tag="IVD26_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079017.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            18163..19860
                     /locus_tag="IVD26_001025"
     CDS             18163..19860
                     /locus_tag="IVD26_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HAP6079018.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKIPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            19853..20314
                     /locus_tag="IVD26_001026"
     CDS             19853..20314
                     /locus_tag="IVD26_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079019.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            20327..21187
                     /locus_tag="IVD26_001027"
     CDS             20327..21187
                     /locus_tag="IVD26_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079020.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFFGRSRRFKLYVLQKDYASNG
                     KYSKKYRIFI"
     gene            21225..21614
                     /locus_tag="IVD26_001028"
     CDS             21225..21614
                     /locus_tag="IVD26_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6079021.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            21601..24048
                     /locus_tag="IVD26_001029"
     CDS             21601..24048
                     /locus_tag="IVD26_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP6079022.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSMI
                     GDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            24053..26161
                     /locus_tag="IVD26_001030"
     CDS             24053..26161
                     /locus_tag="IVD26_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP6079023.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            26158..27162
                     /locus_tag="IVD26_001031"
     CDS             26158..27162
                     /locus_tag="IVD26_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAP6079024.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            27181..28092
                     /locus_tag="IVD26_001032"
     CDS             27181..28092
                     /locus_tag="IVD26_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6079025.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
     gene            28279..28566
                     /locus_tag="IVD26_001033"
                     /pseudo
     CDS             28279..28566
                     /locus_tag="IVD26_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(28754..28969)
                     /locus_tag="IVD26_001034"
     CDS             complement(28754..28969)
                     /locus_tag="IVD26_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079026.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(29228..29395)
                     /locus_tag="IVD26_001035"
     CDS             complement(29228..29395)
                     /locus_tag="IVD26_001035"
                     /inference="COORDINATES: protein motif:HMM:NF018933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6079027.1"
                     /translation="MGSECGHTDGKKSFTIREWTCPICRTHHDRNVNVSINILIKGYV
                     YKHCLRKHQEP"
     gene            complement(29740..31179)
                     /locus_tag="IVD26_001036"
                     /pseudo
     CDS             complement(29740..31179)
                     /locus_tag="IVD26_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(31727..32398)
                     /locus_tag="IVD26_001037"
     CDS             complement(31727..32398)
                     /locus_tag="IVD26_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAP6079028.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
     gene            complement(32747..34198)
                     /locus_tag="IVD26_001038"
     CDS             complement(32747..34198)
                     /locus_tag="IVD26_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP6079029.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            complement(34310..35653)
                     /locus_tag="IVD26_001039"
     CDS             complement(34310..35653)
                     /locus_tag="IVD26_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP6079030.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLEDLFYQNRRELNSKIKKLFLETAVDKIDIQNKKIICVKKDGTRFSQ
                     EYDKLILATGSKQIMLDVPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGKKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHIDNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPVFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            complement(35787..>36205)
                     /locus_tag="IVD26_001040"
     CDS             complement(35787..>36205)
                     /locus_tag="IVD26_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP6079031.1"
                     /translation="GKTEPNAEVTVTLPNGSQYHGTADKNGNFTVKVPKLEAGTKVIV
                     TATDESGNTSEPTNVVVSSNEKDSEKAVSKDNKTDNQGSKQNKNRGKSSPQKQSSKAY
                     PKTGEIDSNIFTISGGLILLGTLGLLGYKNRKKENE"
BASE COUNT        12146 a         6091 c         7166 g        10802 t
ORIGIN      
        1 ccatagaaca acctaatctt gatagaataa aaactgctcg tttagaaaaa aaggacaaaa
       61 tagtcaagaa tattgccagt cttgactcag attattttac tgaattatct aatctatact
      121 tttccatgac ttctttactt gaagtcaaac ttcaagaaga tgactccgac tttctttttt
      181 taaaaagtat tctagaggac tcctttgaat acacgattct atttgccaaa caaaagaagt
      241 ttattaataa agctttaaac ttaaatatcg atgaaagaaa agagttagaa tctgagttat
      301 ttggcaactt aacccaagta caggttaaca atctaaaaag agagataaca gctcgattaa
      361 tatcaaaact tcaataaaac taattattca atcagccaac tcgccaagtt atcagattgg
      421 agagattagt tatgtcaata caaaagtaca caacaaaaag cggtgcacga tatagtgtcc
      481 gcttgtatgt tcgtaaagat gaaaatggaa agcaagaata ctatgtaaaa aaagggttta
      541 aaactgaaaa agaagccaag ttacacgaag caagaaaaaa ggtcgagatt gaagataccg
      601 gctatcataa gccttctaat gacttgttta taacagtgta tgaagaatgg ttgccttctt
      661 ataggaatcg tgtacaagaa acgacatatc aacgtacaaa agaccttttc cgcttgcata
      721 tactaccaaa attcgggaat aagtccattt ctaagattac tcctgttcac tgtcagaatg
      781 cagtcaatga atgggcttta aaattcaaga atatcaaaca gcttaagtct tacagctctc
      841 aaatatttga gtatgccatt tttgcagagc tattacaccg aaatcctatg gcaaatacaa
      901 atctaccaaa gcgggaaaag aaagaaaatg aaaattactt ttcattagaa gaactaaaag
      961 ctttttggga tattctcaat aaagaagagc ctttaaaaca tattttaatc ttccagcttt
     1021 tgattactac tggtatacgt aaaggagagc tagctgctct tcattggtct gacatttatt
     1081 ttgaagaaca gctaatgtat gttagaaaga gctatgcaac tattcgaaat gaagagaaga
     1141 atgcaagaag aaaaactgtc aggattcaaa aaaatacaaa aaatatatct tccgaacgaa
     1201 tattaccaat tgatgcacaa actattgaaa tgttaaaaat ctggaaaaaa gaacaagctc
     1261 gagagctttt gcagtttggc ataaatacaa atacaaaaaa tcaacttatc tttacctatg
     1321 taaatgcaga cggtgacatt aatcaacctt tgcatgcgga ctattcaaat aatatattga
     1381 aacgtttaga gaagaaatat aaatttaagc acgttactat tcatggattc cggcacactc
     1441 acgctactct tctactagaa ggtggagcaa gtatcaaaga aacacaagat cgattgggtc
     1501 ataaaaatgc tgaaactacc cttaacactt attctcatgt tactgaaaaa gctcaacgaa
     1561 atgcgttaga aaaattcatt gcttacactg gtttataata ttgtcattac ctttctcatt
     1621 accagaacga aaaaaagaca ccttctcgca atgagaaagt gtctgaaatc gttggtataa
     1681 caacgattaa cgttttgaaa actgtgaagc tttacgtgct ttcttaagac ctggtttttt
     1741 cttcgtatca ttgaataagt ttgaaaagcc ttgatttata aaggtttttc cgtaaatata
     1801 ttttgttata tttgattaaa tttgaaatgt ttgtgttcta aaatgtgttc taatttaaag
     1861 gcagtatatt tcgtatttta tattaaattt ttaggctcat tcattctcaa atccattcta
     1921 tttagtcaat aaatatttta aaaagacttt ataaacaaag atgttcaagc gagcatctta
     1981 tttttttgtg cctaatttga aaggagaaca tttcatgtat aaaaaacaaa aaaagaaatt
     2041 atgtgtatta actattttga gtttggctgt tcaatcaatt gtaggagcaa ttgctcctac
     2101 gattgctttt gctgatgaaa ttacccatcc acaaacggta accgtagaac tagatttagc
     2161 acatcaatat gctgttgaag gaacttttag tgatggtcgt ccaatgtcag aagtcactgt
     2221 tccgcattat gcagtgtaca acggcgttaa acaagatatt ttctgtgttg aaccaggagt
     2281 cccgatttac aatgagttca ctcctggata tgagaagaac ccgttaccag atatgtccga
     2341 taaagccaaa ttagtttccg ttttatggaa aaaagtaggt acagatgcag atactcatat
     2401 tgtggcacag aagatgatct ggcaagaagt taatgggtat acccttcact caataaaacg
     2461 atcagatggt agtgccgtaa atatcgcagc cattgaggca aaaatcaatc aagccattgc
     2521 cgattatcag aagaaaccaa gcttccataa tagtacggct aaaacagtat tagggcaatc
     2581 gactactgtg acggatacga ataatctgaa tttgtcagag ttcgatgagg ttgtggaaaa
     2641 taccgcaaac attgattatc gtgtgaatgg caatcagttg ataatcagcc caaatgccaa
     2701 ttcaaaagaa agtggtgtgt tgacgcttaa gaaatctgct ggtaccggaa cacctgtcgc
     2761 ctataaaaag gctggccaac agactttaat ggccggggcg atcgataagc cgaacactta
     2821 tacggtcaaa attgatgtgg aaatggaggg ttctttgaag attaaaaaag ttgataaaga
     2881 atcgggtgat attataccag gaacggtttt ccatttagac tttggaaaaa ctttacccgc
     2941 aaaagacgtg accaccgata aagaaggcat tgcgacctta gatgagattc ctcatggtac
     3001 aaaggtaacc attactgaaa aatcggtgcc ggcgccttat acgattgata ccacacccat
     3061 gactgccaca attaaagcag gtgaaaccat ttcagtgact tcaaaaaata cgcgagaaaa
     3121 aggtcaaatt attctggata aaaccggaat tgaaacaggg agtgatcttt ggaacgataa
     3181 ttactcttta gcgggcaata cgtttgccat tcgcaaggat agcccaactg gtgaaatcgt
     3241 ccaagaaatg accacggatg aaaaaggtca tgcagaaaca ccaaaagaga ttgccaatgc
     3301 gttggaattg ggaacctact atgtgactga aaccaaggct agtcatggct ttgtgaatac
     3361 tttcaaacca gtaaaagtcg aattgaatta tgtcaatcaa acagtggctc ttgttaccag
     3421 taacgtaaaa gggcaaaacc aagaaattac tggtgaaacc actttgacaa aagaagacaa
     3481 agataccggt catgaaactc aagggaaagc tgagtttaaa agagctgaat acaccttgtt
     3541 tactgttaag gatggaaaag cggtcaaatg gaccgagaac tttaaaccag aattgttgaa
     3601 gggaacgaaa gcttctgatg aaaccgtaac tttgacttta gatgaaaaga atcaagttgc
     3661 cgttaaacac ttagcgatta atgagtatta ctggcaagaa accaaagcgc ctgaaggata
     3721 taccttggat gaaacaaagt atcctgtatc catcaaaaag gtggatgata gcgaaaaaaa
     3781 tgctgtgatt actcgagatg ttgcggcaaa agaacaagtg attcgctttg gctttgattt
     3841 ctttaaattt gctggatcaa ctactggcac tgccgaaact ggcttcaatg atctaacctt
     3901 taaagtgtcg ccattggaag gaaccaatga aatcaccggt gccgaagatg aagcgaccac
     3961 agcttataac gagcaattag ggtttgatgg ttatggcaag tttgaaaatc ttccttatgg
     4021 ggattattta cttgaagaag tagaagcccc agaaggtttt caaaagatta cgccattaga
     4081 aatccgttct acttttaaag aaaataaaga ggattatacc aagagtgatt atatctttac
     4141 tattaccgaa aaagggcaaa agcaaccgat taaaacggta acggtccctt atgggaatct
     4201 aaccaatgag aatttctcag tcagtttgaa ccgtttgatg ctttatgatt tgcctgagga
     4261 agaagatagc ttaacttctc ttgcgacttg gaaagaagga gataaagaat tgactactct
     4321 tgattctacc gagctagtcg ataaattgag ctataatcta catgaaatca aagaagactg
     4381 gtatatcgta gctcaagcca tcgatgtaga tgctacaaaa gctgcccaag aaaaagataa
     4441 aaaagccaaa ccggtggcga ttgcggaaac aaccgcaact ttagcgaata aagagaaaac
     4501 aggaacttgg gagattctgc ataaattaac tgtcgaacaa gttttagaca agaccattgt
     4561 cttattcaac tatgtgtatg aaagcaaaga agcctatgaa gctggtgatg agccggtagc
     4621 gaaggatgct agcttgaaca atcaagcgca aactgttaat tgtatggtgg aacgtcatgt
     4681 ttccatccaa accaaagcgc acttagaaga aggttctcag acctttactc atggtgacgt
     4741 ggtagatatg tttgatgatg tatccattac ccatgatgta ctagatggct caaaagaagc
     4801 ttttgaaaca attctgtacg ctttatttcc agatggtaca agtaaagaaa tttggaaatc
     4861 tggcaagatt gattacgaag tgaatgacaa agaatttacc aaaaccgtac ttgcggaaaa
     4921 agtggataca agtaaatatc cagaaggtac aagttttacc ttcaaagaaa ttaactatga
     4981 caaagatggg aatatcaatg gaaaacacaa tgaagatttg aaagaaaaat ctcaaacttt
     5041 aacgcccaaa aaagttccga caacaccaag tacaccagaa caatctgaaa tgccaactgt
     5101 tccaagtggc tctcaagaat ctagtcctac agtgaaggca ttccctcaaa ccggggagaa
     5161 aacttccaat gtgctactgt tcattggctt tagcttgatc tttgcgacgg ctggctatta
     5221 tttttggaat cgtcggaact aaggtgataa gatgaaacat gtaaatagta gaaaacaata
     5281 cgcgcgaccg cctcctaaaa aagtggtcgc gctatttttg tattcaaaac taacaatgaa
     5341 aagaggaaaa aatatggaat tgaaatttgt tgtaccagat atggtcgaga cgttcggaaa
     5401 actaacatac ggtggtgaag gtgaagttct atcggaaggg tatggtcgaa atactacaat
     5461 tgttggtcga agttaccatc tgttttcaaa taaacaacgg gccgatgata ttgaagtggt
     5521 ggtagctgcg gaagccggcg aaaaggattt tgaccaagat caaccactaa aagctgtaaa
     5581 tccccactta attgccaaag gctatgaaat tgagaatcgt gggtttaccg attacgtgtt
     5641 gtatgttgat gatttagtga aagcatagga ggaaaagaag atgagattaa cagaaggtat
     5701 tgtcgtagat tcaggattaa cctttggcaa gttgcgtttt tccgcattac gtcgagaagt
     5761 acgcaagcaa aatgaggacg gaacggttag taacgaggta aaagaacgga cctataattt
     5821 gaaatcctcc gcgcaaggtc gaatgatcca agtcagtatt ccagcaaatg tacccttacg
     5881 cgagtttgct tatgatgcag aggtagagct ggtcaatcca atcgtggata cggtcgccaa
     5941 ttatgttttt cgggaaggaa ccaccgttaa ttggtttatc aaggcagatg atttagtctt
     6001 gaaacgacaa ctgaatcaag gaaaacctac gaaccaaaat gaaggaaaga aataggtgaa
     6061 gaatatggaa attaatgttg aacatatttt agattgtctc gatcaatttg gcaaaggtga
     6121 gctaacggag gaacaactca ctaacgcatt aacctatgat gaaaaaatgt ttctgattat
     6181 gcatcaaggg ttactggaag taggtaacga tgccaaagaa gactttgatg tactggattg
     6241 gttaggggaa gaagagtctt tctttatggt tgtcgaggta aatgaaagtt tatgtcggca
     6301 ggcagaatct gttttggaag aaatcgatgt ggagatgccg gatgccatcg aaagattttt
     6361 aaaacaatta gtggaaacga aacaacttcc cgtagtagta aatgactagc ataacttttt
     6421 gaaattgccc aatgaaatcc tattgggctt tttcgactgg aggtggaaac catcaaaatg
     6481 tacaaaggac atcgcatacg cgcaggagat caacacttga tttatcactt tgttcttggc
     6541 tggctaatct ttttgttcat tggttggatg agcgtctttt atttacaaga acttagacaa
     6601 tttgatattt ctaaggtatc attttccact agtgaaattg gctggtctat gaaggatgta
     6661 atctgcttgc taggaagtct cgctctttca ggaagcatga tgttacttta tatacacttt
     6721 tttcaggatc attggcgaag tctttggcat cgacaaaagt tagctcggat gattctagaa
     6781 aaccattggt atgaagtaaa gcagactcaa ggtgaaggtt ttttcaaaga tttgaatagt
     6841 agttggacca aagagagtat cagttacttc cccaaaattt attatcgaat gaaagatggc
     6901 ttactttcta ttcgcgttca aatttcactg ggaaaatatc aggatcagct attgaagttg
     6961 gaaaataagt tagaaagcgg actgtattgt gagttagtag aaaaagaact caaagactcc
     7021 tatgtggaat acaccttgtt atacgatatg attgccaatc gaattgggat agaagaaata
     7081 gtggcagaaa atggggcgtt gcgattgatg aaaaatcaag tatgggcgta tgattccttg
     7141 ccgcatatgt taattgctgg cggcacaggt ggtgggaaga cctatttctt actcaccatt
     7201 attcaagcac tattgaagtc agatgcagaa ttgtttatcc tcgatcccaa aaatgcggac
     7261 ctcgccgatt taggtacgat aatgcctcac gtatactccc aaaaagaaga aatttctgaa
     7321 tgtgtggaag atttttacga acgcatgata gctcgtagta ggtcaatgaa agaaatgccc
     7381 aactacaaaa caggagagaa ttatgcgtat ctcggacttc cgcccaactt tttaatcttt
     7441 gatgaatacg tggcttatat gggtgcgaat cgttttccta caagcatcga atagatgtga
     7501 aatggaagcc tattgagatt atcaatagtg acaactaatg ttttgagaga tggaatgaaa
     7561 gccttcaagt tgagctgaaa catccccgct aatactccta catgctctaa tcaatgaagt
     7621 agattggttt tggtatgaag ctaggtgaag tcgtctgaaa tctgcctaag tgcttgagca
     7681 taaggctgac tatagggcgg gcggctgaaa aagataacta tggtaagaat gtctgaaaat
     7741 gactgacgaa tctgcgaatg tacgggtcta aaaggctgat cttattgaaa gataggaaca
     7801 tacggacgta tggtgagata ccgacaagta aggttccatg atatgaaaat cgggatagct
     7861 aacgaagaag ctataatttc acaggctcat agtagatacc taaggttata catgatagct
     7921 aaaaacattg gaacgatgta agcagaaaac tatcaattaa atgactactt ctagataggt
     7981 gcatataagt aataacgaaa ttgctttgtt tctgtgaaag taagggcaca gtaccgatga
     8041 agcgtctaac aaatgtggag ggatagccct aagtctattt aataacaatg aatgttgaaa
     8101 cagatgaagt tcaaggatct ggtaagaacg tgggaaaatc cgttatggag gtgccacgct
     8161 tgaacacaaa aatacgttac tgggaatatt atgatctaca agaaacattc gatcagctat
     8221 ttactcaaag tagaaacggg aaaaagtttt atcaattata tgagttaatc atttctgaaa
     8281 ataatattct tttagcatac cgtactatca aggcaaacaa ggggtcttcg acaccaggaa
     8341 cggattcctt cacaattgat aactataagg aaatgaacca agcagagttt atccatctta
     8401 ttctcagtca tttagaaaat tacaaaccaa aatccataaa gcgagtaatg atacctaaac
     8461 ccaatggtga gaaacgccca ttaggaattc catgcatgat tgatcgaatg atccaacaga
     8521 tgttcaagca gatactggag ccaatatgtg aagctaagtt ttatgaacat agctacggtt
     8581 tcagaccatt gagaagtgca aagcatgctc taggtcgcat tatgtatctc ataaacatca
     8641 gtaaaatgca ctatgcagta gacattgata tcaaaggttt ctttgataat gtaaaccacc
     8701 gtttactgat aaaacaatta tggaatatag gaatttgtga caaacaagtc ttagctattc
     8761 tttcaaaatc tctgaaatca cccattcaag gagaaggtat cccgagcaaa ggaacgatcc
     8821 aaggaggtat catttctcca ctattatcta atgttgttct aaacgactta gaccattggg
     8881 tctcaaagca gtggcatacc tttgaaacaa agtatcccta tactaaaggt tacaataaat
     8941 ttcgtgctct aagagataca aatctaaagc aaggctatat tgtcaggtac gcagatgact
     9001 ttaaaatcat gactaatgat tatccgacag cattaaaatg gttccacgct gtcaagcttt
     9061 acctaaaaga cagacttaaa ttagatattt ccaatgagaa gtctaaaatc gtcaatttgc
     9121 gtaaatgtaa gtcggaattt ttaggattcg ctatttgcgt gaaacaaaaa gggaaaaaat
     9181 gggtttgtaa ttcacgtatt tctaacaaaa aaaaggatca gattaaagaa gagattaaac
     9241 aaagaatcaa agatattcaa aagagtccta cagcacaaaa tgctctcctg tttaatgctc
     9301 tcgtgctcgg tgttcataat tatttcaggt atgccactca tattaattta gatttgaata
     9361 ggatgaacta cgttctttca ttcactactt acaaccgatt atcaaattgt agtacaagat
     9421 gttaccccaa caaagcttcc ccaacttaca aaaagtttta ctcaacaacg atgaaaacgt
     9481 ataaagtagc tggagtctat ttgtaccctc tttgcgacgt atctacaaaa acaatttacg
     9541 gatttaatac ggaggataca ccgtttactc cgtttggtcg tcaaagattg gagcacaaaa
     9601 gcctacagtc tcttgtgttc caagaattaa gaaaattgat ggaatcgaaa ataccgaata
     9661 gaacggttga gtatttagat agtagaatat ctcgttactc aatgaaatca ggcaagtgtg
     9721 agattacaaa acaatttttg ccagcaaaag ccgttcactg tcatcactat ttgccaaaaa
     9781 gtcttggtgg agacgacaaa ttcgataact tgagaattat tcataaggat atccatcttc
     9841 tgatccatac aacaaataaa atgataatcg atcactacgt gcatgaactg aaactggtgc
     9901 cagagcaaat agcaaaaatc aacctttatc gaaagatgtg taatctgcaa aacattcaat
     9961 agaaaataaa tagatggaac gccgtatgag gtgaaagtct cacgtacggt gtggagcggg
    10021 ggaaaagatg gagattatat caaattctta cctatcgcta tagatgttaa cgacaaaaga
    10081 aagtgcggtg attttgaata agcttaaaca aatcgtgatg ttaggccgtc aatctggttt
    10141 ctttctgatt ctagcttgtc aaaggccgga tgcgaaatat ctaggagatg ggattcgcga
    10201 tcagtttaac ttccgtgtgg ctttgggtcg tatgagtgag cttgggtatt ccatgatgtt
    10261 tggagaagtc gataaaaatt tttttatgaa acgcatcaaa ggacgaggtt atgtagatac
    10321 agggggcagt gtgattagtg agttttatac gccacttgta ccaaaagggt atgatttctt
    10381 aagggaaatt agcaacattg ttggattaac cgttcatacg gaaagagaaa ataatagtgt
    10441 gtagcctagg aatatcaata atcctgggct tttttattga ggtgatttat gacattttta
    10501 gatttattcg ccgggattgg tggctttcgc ttaggtatgg aacaagccgg tcaccagtgt
    10561 atcggttttt gtgaaattga tgaatttgct cggaggagtt ataaagcaat ccatgataca
    10621 aggaaggagg tggaaatgca tgacatcaca agtgtatcag acgaatttgt tcgatccctc
    10681 ggaccagtgg acatcctttg cggcggcttt ccgtgccaag ctttttcaat tgcgggaaag
    10741 cggcaaggat tttccgatac tcgaggtact ttattctttg aaatcgctcg gttcgccact
    10801 cttctccaac ctaagtttct attccttgag aacgtccggg gattgctcaa tcacgaagga
    10861 ggggctacgt tcgagacgat cctccgaacg ttggatggat tggggtatga tgtggaatgg
    10921 caagtgctta actcaaaggc ctacgttccc caaagccgtg agcggatctt ccttatcgga
    10981 cattctcgag atgcatgtac cgaacaagta tttcctatca ttggatcgtc ttcaacatct
    11041 gatcaaaaca tcagaaactt ggtaaatatc aatccttcca atcgaggaat gggtggccaa
    11101 gtctatggtt cagatagcgt agcaccaacc ttgaccggtg atgaaggaat taaaattgcc
    11161 ttaccggtaa aggatgggat ttctgtagcg ggtatgttgt cgggaaattt tgaacaaggc
    11221 aataggattt atgaggtaac cggaacagcc cccactttgt caacgaaaca agggggaacg
    11281 aagattatga ttcggaaaaa tgaaacagaa tatcaagagg tgaagccagg ggacagtgtg
    11341 aacctggctt ttcctaattc cacaagtcgc cgaggtcgtc tgggaaaaca aagtgtgcat
    11401 accttactaa caggagacca acaagcggta gtcacggatc agtaccagat tcgaaagtta
    11461 acacctaggg agtgctggcg gcttcagggc tttccagatt gggcttttga tcgagcttct
    11521 caagtcaatt cagatagtca gttgtataaa caggccggaa actcagtaac agttccggtc
    11581 atttttgata ttgctagaag attaaagggg gtaaaagcat atgatttatg acgagttgat
    11641 tggagaaatc tactggatga ttggcaagat tcaggcagat ccgaaattgg aagaagaact
    11701 gtaccggctc aattttgata ttcgcaaaaa cggggtgaaa gtccaggtga ttcgtatgta
    11761 gtggatgagg aaacggatgc tcgaatggag ctcaatcaag tcatcggtga attggaacga
    11821 attgcggacc ttgccaaaga acctgatatc cgccaatact tgtttgagat aaaagcagag
    11881 ttggaaattg agggtatcac cgcggagtaa tagggaaata acccactgat aggcactgac
    11941 cgcgggggat ttgcgaagca gaaatcctcc gtggtgctgt gcctgttcat ggacggcggc
    12001 agccggccat gatgtctcac cccccgtatc taacaggggg gtacaaaaac acaaaaaaca
    12061 agcaagtaac cataaaaaat gcttgttgta tcaaggatat taagtaattt gtataggtgt
    12121 taactcattt ggaaaagtta acaccttgaa tttggaggtg aaaacttggc gcaacgaaat
    12181 ttagattatc ggttattaaa agaacgacgc aacgaatatg gcgtttcaca aaataaatta
    12241 gctactgctt gcggacttag ccgcccatac ctaaatcaga tagaaaacgg tggcgtaatc
    12301 gcctctacaa agaccatgag aaaaattttt gatcaactgg aaagtttcaa tcccgattta
    12361 cctttaacgt tactatttga ctatgtaagg attcgctttc ccacaacgga tgtgcggaaa
    12421 attattcaag aaattctcca tttgaaattc gagtatatgc ttcatgaaga ttacgccttt
    12481 tactcctatc aagaacaata tgtcatgggc gatattgtag tgatgttatc tcatgaagaa
    12541 gataaaggtg tccttttgga attaaaaggt cgtggttgcc ggcagtttga aactttttta
    12601 ctcgcccaaa agcgtagctg gtacgacttt tttgaagatt gtctaaaagc cggtggcgtg
    12661 atgaaacgct tggatttagc aatcaatgat cgagtggggc tactggatat tcctgattta
    12721 acgaaaaaat gtcagaagga agaatgtatc tccttgtttc gtaccttcaa aagttaccgt
    12781 tccggggaac tgttgaaagc tgatgaaaag gatggtatgg gcaatacctt atatattggc
    12841 agcctcaaaa gcgaggttta tttttgtttg tacgaaaaag attatgaaca atatatcaag
    12901 ttagggattc cattggacca gaccgaaacg aaaaatcgtt ttgagattcg gttgaaaaat
    12961 gaccgtgctt attatgcgat tcaagatttg ttaaaaggtc gtagcattga aagtaccacg
    13021 ttttccatta tcaatcggta tttgcgattt gcggataaag tagatggaaa acggcgaacc
    13081 aattggccct tgaatgaaca atggggtcgt tttattggac ggaatcggaa agagattcaa
    13141 ttaacttctg aaccgaaacc gtataccatt gaacgaacat taaattggct aggtagacaa
    13201 gtcgccccta cgtggaaaat ggctaaggag ttggatcgat tgaatcaaac aacgtatatc
    13261 caggatatgg tacagaatgc gcgactctcg gaccggcata aaaagatttt ggagcaacaa
    13321 agtatggcaa tcgaaaactt gattgtatga aaagaggaat tttgatggaa attgtaaaag
    13381 atatgttatt ggtacttggt ggcagtatgc ttggtgttac cgtgatgtgc ttgatgaatg
    13441 caagtgcagc agcggattga gcaatggaaa agaaaggaaa gtgacaaaat gaatttcgga
    13501 caaaatttat gtgcgactcg ttccttagtg aaaagctaag gcactaataa aagaacgaaa
    13561 aagtttggtt attaggagaa ctgataatct gacaggtgga atgatgaagt aacgctctga
    13621 aacgcctgcc ctgagcctcc gacaagcatt gtatgaggaa actcagaatg tttgaagctc
    13681 ggtaaagacg gctgaaagat accgtaatag ttgatgaaca tatatcttct atcgaaaact
    13741 atccagaggt gggtagcgta tccaacaggt cgggggtcta taaaatatct atggttagaa
    13801 tgttctataa ggaactgacg aaacagcgaa tgtacgggtc taaatttgaa ctttgtagaa
    13861 atgcaaaggt acgagaaatc gtagctggtg tggcaaagta agaatatagg ttatgaaatg
    13921 ccatataacg ttacaggcgg tatcaagcca gcaggcttat agctagtgac ctaaggatat
    13981 atatgtatag ataagattat cggaacgagg aaaggtattg ggttctcatc aagagaataa
    14041 actgacgaag aacaataagc agttgaacta atgctgaaaa gcagagggcg aacctaagaa
    14101 attcttgtaa tgagaatgga ggaatgccct caagtcgtgt atatattaga aaagtattat
    14161 gttgtttcaa taaggattac gagtaagata aaaaagctca ctcaatttca agtaaaggag
    14221 tgaagcctta tgcctaaaaa taaaaatgaa acattgtgtg tagaagattt aagacacgct
    14281 gaatattacg aaatgcaaaa cacctttgat gatttatatg ccaaaagtaa gaatggagat
    14341 attttcactc atcttatgga tattatccta tcgagagaaa atatattact ggcatatcga
    14401 aatatcaaag caaatgcagg cagtaaaaca gcaggaacag acggtacaat aattaaagat
    14461 attggcaaat tgccagcaga aacagttgtc aaaaaagtaa gatacattgt tgcaggcagt
    14521 ccacatgggt atcgacctaa gccagtgagg cgaaaagaaa taccaaaacc aaatggtaaa
    14581 accagacctc taggtattcc ttgtatgtgg gacaggctta tacaacaatg tataaaacaa
    14641 gtattagaac caatctgcga agctaaattt agtgaaaaca gctatggttt tagacctaat
    14701 aggtcagttg aaaatgcaat aaaagcaacc tataaccgcc tacaaatcag ccagctacat
    14761 tatgtgattg aatttgatat taagggtttc tttgacaacg tgaaccattc caagctgata
    14821 aaacagatat gggctatggg aatacgggac aagcacttga tattcatttt aaaaaggata
    14881 ttaaaagctc caatcaaaat gactaacggt acaataacat atccagagaa aggaactccg
    14941 caagggggaa taatatcccc actactagca aacattgttc ttaatgagtt agaccattgg
    15001 gtagaaagcc aatggcagga aaatcctgtt acaaaaaact atgtggttca tatcaataaa
    15061 agcggtagcc catgtaaaag caacgcttac aaagaaatga agaaaacaaa gttaaaggaa
    15121 atgtatatgg ttcgttatgc agatgatttt agagttttct gccgctacaa ggaaagtgct
    15181 gaaaaagcca aaatagcaat cactcaatgg attgaacaac gattaaaatt ggaagtatca
    15241 caagaaaaaa caagaattgt aaatgttaga aaaagatact ccgactttct tggtttcaag
    15301 attaaaatga taccgagaag aaagaagtta gttgttaaat cacatataag tgataaacaa
    15361 ttcaaaaacc aaaaagacaa gctggtatca caggcaaaga aaattgcttc tccctcaaaa
    15421 gggaaaacgg aattagaaga aacaagactt tataattcaa tggtattagg tatgcaaaat
    15481 tattatcaga ttgcaacgaa tgtaaatctg gattgtatga aactgaatag agctgtaatg
    15541 gctatcttca ctaacagatt aggtacaaac aaaaggggca gattgagaaa aacaggcaga
    15601 caacttacga caaaggaggc aacaagatat ggtaaatcta aaatgcttcg gtatgttgct
    15661 ggcgagggcg aacctatttt ccctgttgga tatatccaac acagaaaacc aatggcaaag
    15721 gtgtatttag cgaattgcta cactctagag ggaagaaaat ttatccacac caatctaagt
    15781 gttgataaat tactgatgta ccagttaatg aaattatctt tggaaaatcg cacaatagaa
    15841 tacgcagaca atcgaatttc gctattttct gctcaacatg gaaaatgtgc tataactctg
    15901 gaagaatttc aacaagctaa tgaaatacat tgtcatcata ttgtaccaac tggagctggt
    15961 ggaaatgacg attataaaaa tcttattttg gtaaaagagg cggtacaccg tctaatacac
    16021 gctaaaacag aagaaacaat acaaaaatat atagctctat tgaagctaaa taaagtccag
    16081 ctcataagac taaataaata tagagtatta gctggcaatc aagaattaaa cttgatatag
    16141 gtctactaca taaatacttt tcaatataaa cacgatggaa cgcggagtgc ggtgaaagtc
    16201 gcacgctccg tgtgaatggg gggaaaagtt tgagatattt ataatatcag gaacttacct
    16261 atccatatat caatggtttt taaccaatgc tcaatcttta gtcttactag cgattgtggt
    16321 cattggtttg tttttaggat ttaaacggga gttttccaaa ctgattggct tcttggtgat
    16381 tgctttgatt gcggtaggtc tggtctttaa tgcttctggt gtgaaggatg tcctactcaa
    16441 tttgtttaac cgaattgtcg gtgcctgagg gggaatcaca atggaacaga tgcgtgttta
    16501 tattgcgaac cttggaaaat acaatgaagg tgagttggtg ggggcatggt ttaccccacc
    16561 tgtcgatttt gatgaagtga aagaacagat tggattaaat gacgaatatg aagagtacgc
    16621 gattcatgat tatgaactgc cttttgagat tgatgagtat acgccaattg aagagattaa
    16681 tcggttgtgt aacttagcgg aggaactaga aggaacgcca attggtgaag ctgcttctga
    16741 gattcaacac gctttcttca attctttcga ggaaatggta gagcatgtgg atgatattgt
    16801 ctattatcca gattgcgatg atatgagtga tgtggcgcat tacttgattg tagaagctgg
    16861 tgattttggc gaagttccag aacaattgaa gccgtatatt gattttgatg cttgcggtcg
    16921 agatttggag attggaggaa attatttggt tactagtcgt ggagtttttg agtatccaga
    16981 atgaatcaaa cactatatat agtgtttgat tagtatatgt aagcaaaaaa acacaatata
    17041 tagagtgcaa actgaagggt aatgtgatat aatatttgcc gaagaaatat ttttgaaatg
    17101 aggtaatatt atggcaaata ttcaaacaag ttttattgat ttccataatt caattagatt
    17161 ggacgtagaa gacaatacgc tacttaagga ctataaagac caagtaattg atggattaaa
    17221 agattactta cctgatgatg tgaagtttga aactttttta cagggaagct attctgttta
    17281 taccggaata aaaagctgtg atgaaaaaat tgattttgac atcgatattg cagttgcttt
    17341 cgaaattgat catactgttt atgaagatcc aagggagcct aaactgtggg taaaagaggc
    17401 gctagttgaa atttttccta atgctcaagt taatttaaaa gtaccttgtg taactgctac
    17461 atttactgga aaaaagacaa aaaaaaatgt gcacgttgat gttgcggttt atgctaaaga
    17521 agatgaaaat tatttcttag caaaagcaaa agaattcagt gctcccgaaa accgatgctg
    17581 ggaggaagcg gatcccaaag tattaaaaga gaaaattaat agtcatgtag cagattcaga
    17641 tgatcgaaaa caatttcgaa gatgtattcg ctatttaaaa agatggaaag ataacaattt
    17701 taaccaagaa tataaaccaa caggaattgg acttacaatt aatgtgatgg atacgttcct
    17761 agttaataag tccactgatt ttttaactag aaaagttcag tataatgata tggaatgtat
    17821 gaagcagatt gtttcttcgc tgaaagattc atttgtgtat gagtacagtg aaacagatgg
    17881 ttggcattat cgtctacatg catatcttcc agtgaagcct aacagtgaca cctattcaaa
    17941 aatgacagtg aatcagatga gtgattttaa aaacaaactt tctaaattat atgatgattt
    18001 gattttcgct atcgatactg aagatgagta tgaagctaca aaacgattaa ataatcaatt
    18061 tggggaggat tttttaatta tttcagaaga agaagttaca gaaaaaaact taagaaatgc
    18121 atttgttaca gactatccga gtgcttaggt tggtgttaaa gattggatta tactgatatt
    18181 ttaaaagaaa agctaacaga tgttgtgcgt ttattcgatg gtaattacta tggggatttt
    18241 tcatttgcta caattggaaa gttgcgttta aaaattgaaa taccaaaaca ttttccattg
    18301 gtacttccta ggatttacat tcataatttt gatcatttag gactttacct accacatgta
    18361 gaaaaagatg ggttggtatg tttttcttca gatataaatt atttagtaga tgaagaaaat
    18421 tcagaattgg ttttattgca gtgtgttaat aaaactataa aaacaattga ggaaggtttg
    18481 aaagggttaa ataaaaatga ttttcgaaaa gagtttgttg ctttttggga caaacaagag
    18541 aatcaaattt cgttattcta cctttgtgaa ccagcgttgt ttatcaagtc agttgataca
    18601 ataatgtacg gtaagtcttt ggttgctttg gataaagaga acgaattaca attaaatgca
    18661 gcgagtagat tgtttaatgg agagaaagaa gatactcatg aattagatgc atactatgtt
    18721 ccaattagaa acaagaataa tattatgccc ccgaagaata ataaagcatg gtcaaagaag
    18781 gatattttac aaatagtaaa aaaaaatgta acaggtgcaa ataaaagatt ttttttaaaa
    18841 cttgaaaaaa gaaagaatag acataatgtt ttacttattc tagatatccc aattgaagaa
    18901 aagtcaaata atgtcataat tggatttctt tttacaaaac aatctggatc tataaaagat
    18961 tataagggta cgcctaggac tgtattagtt cagcgtcatg atgaattata tttggtgaat
    19021 agaacgagcg gagaaaacta tggattgggt gctaatatag ctattgttgg ggtagggtca
    19081 gttggcagta aaattgctga aaatcttggt ccattaggtg tgagaaagat gacactcata
    19141 gacaatgatt gttttcaagc tgaaaatttg tatcgaaatt cacttggtgc agatagttta
    19201 aaaaatgccc gatctcagaa taattttttt aaagttgatt taatgcagga ggagctcgaa
    19261 aaaaaaatcc catacctttg tgttgaagtg gagtcaatga acgttttaga cttaattagt
    19321 atgcaacctg gttttttcaa ggaatatgac tatgtttttg tttgcatagg agatacaatg
    19381 gcaagcctgg ctttaaataa ttatttttcc aaaagtagtc aaaaagtttt ctattcttgg
    19441 ctggagccat atggcattgg gggacacact ctatttataa attattctct aaatcaaaaa
    19501 ggttgtttca attgtcttta tacagattca aactctaaaa ataggtgttc aaatagagct
    19561 tctctggtaa aagaaggaca aatttttgaa aggactttag cgagttgccg ctcaaaattt
    19621 ataccatata atgctattgc ctcgacggaa tgtgcaatta atgcaataaa acttttccat
    19681 aaagtcaatc aaaataatat gaccaatagt actctttttt catggatagg agatgggagt
    19741 acttttgaga atttaggata tcaatatagc gacagaaata cttttcttaa tggagtcaat
    19801 aagtttgaag aaagattctt ttctaaatat tgcaaagtat gtggggagtt agatgattaa
    19861 attttcgtgt gaccgtattg tcattgaagt aagggatgaa gttcttaaga tatttgaaca
    19921 atatcggcag ggaaaggatg acttgcctga agctggagga gttcttcatg gaaaaagact
    19981 taagaatggg agcataataa ttaccgatat aacaacacct caaataggag atatacaaaa
    20041 aagattactc tttaaaaaaa accgagaaat tcatcaacag ctttctaatg agaaatggat
    20101 agaatcaaat aagttttcta ttgcattggg agaatggcat actcatcctg aagctgtacc
    20161 aactccatca aatgttgata agaaaagctg gagactgaac gtgagcaagc aacatgatga
    20221 tagagtttat gtttttatta tcgttggatt ttctgatttg agaatgtggt tactgtcaaa
    20281 aaaatcagat attaggcagg ctataaaact ataaaggagt gattaggtga aatcacaaaa
    20341 gaatatttgg tggtgggggt ttttagtagg aaaggtaatg ataccagccc ttctcttaat
    20401 ttctctaccg atgattactt ttttctttac caataaaaaa atgagtaaag aagccgtgat
    20461 ttttttcttt ggagaccaaa aagctacctt tattgaaacg ttagtaacat ctcttcagct
    20521 taatttgaat tacatttttt caattattat tgttatatcg ttattgaatt tttttaaaaa
    20581 aagaaattca ggaaaggtgt ttaactctaa tggaaatgtg tactacaact atttttattt
    20641 tgtattttgg gtagcagcaa ctttacttgg ttatgataaa attcagattg caggaattcc
    20701 tatacacatg caatataagt tggttttgag tggaattttt tctgaggtgt tgccagatat
    20761 atacgatgat cattacgaca gtgatggaac atgtaaagta agcattgaaa aagaaaattt
    20821 cgatgacatc gatggatatg actctgtgaa cttactgatt attgatactt acgatataaa
    20881 aatgagtgaa ttatctatgg aaaatcaaac atatcctacg ataattgtta gagggaattc
    20941 aatagatgga gttcgtaaag ttaatagatc tttaatcttg gaaataaaaa aaacaatgga
    21001 tgaaattcaa aaaagtgact ttaaaaaagt atttgttgct tcaacatcta atccaaaaaa
    21061 tagtatcaat attattaatt catcgtttag atttttcggt cgatcacgta ggtttaaact
    21121 ttatgttctt caaaaggatt atgcaagcaa tggaaagtat agtaagaaat atagaatttt
    21181 tatttaagaa ggaatttttc cttcttttta ttttggagga aactatgaaa aaaataaaaa
    21241 gctacaccag tatttgggca gttgaaaaag tcatttatgc gattaatgac tttcagctgc
    21301 cttttcctgt gacctttaac cagatggctt ggtttgtttt atccttgatg tttgtcattg
    21361 tatttgccca tgtgcctccg ctatccatga tagagggggc ttttttaaaa tacttgggca
    21421 ttccgatagc ggtcacttgg ttcatgtcgc aaaagacctt tgacggtaag aaaccattgg
    21481 gatttttacg atcctttatc agctatcact tacggtttaa ggtcactttt gcaggaaaga
    21541 aagttaaaga acagaagaaa cgatgggacg aaccaatcac cttggtaagg agtgtgaatt
    21601 atgtacccga ttaagtatat tgaaaataat cttgtcttta accaagaagg cgagtgtttt
    21661 gcttactatg aattagtgcc ttacaattac tcctttttgt cacctgaaca gaagtatcaa
    21721 gtacatgata actttcgcca attaattgcg caaaatcgtg aaggtaagat ccatgcctta
    21781 caaattgcca cagaaagtag tattcgtgcc acacaagaac gttcgaaaaa ggaaattacc
    21841 ggtagactca aagaagtagc aaagcaacga attgatttac agacagatgc attagtatcc
    21901 atgattggcg atagtcagat tgattatcgc ttctttattg gctttaaact gatttcgaca
    21961 gatgaagagg tcaatctaaa gaatctcagg aaatctttct tttctggact tcaagaattt
    22021 gtctatggag tgaatcatca tttgatgggt gattttgttt ccttatccaa tgaagaaatt
    22081 cgtcgctata ccaagcttga aaaactaatg gaaagtaaat tggctcgaag atttaaagtc
    22141 aaacgagtaa cgccgagtga cttgacgtat ttaattgaac atatctatgg tgaaaaaggc
    22201 acaccgtttg aagaatatga attccagcta ccaaagaaaa agctgaaatc agaaacgctg
    22261 gtgaaacgtt acgacttatt acgtcccact cgttgtttga ttgaagaaaa gcctcggtac
    22321 ttacggatgg aacatgaaaa tcatgagtct tatgtagcgt acttaacaat taataccatt
    22381 gtaggggaaa tggagtttcc ttcctcggaa cttttctatt accagcaaca acaatttacg
    22441 tttccgattg atacttcaat gaatgtggaa attgtgacga ataaaaaggc cctagctacc
    22501 gttcgtaata agaaaaagga attaaaagat ttagacaacc atgcctatca atctgataat
    22561 gaaacgaact ccaatgtatt agatgctttg gattccgtgg atgaattgga aaccaccttg
    22621 gatcagtcga aagaatccat gtataaacta agctatgtgg ttcgagtgag tgctaaatca
    22681 gtggatgaat taaaacgccg ctgtgatgaa gtgctcgatt tttatgacga taccaatgta
    22741 aaactagtcc ggccctttgg cgatatgatg ggtctacaca aagaattctt accctcaagt
    22801 aagcgataca tgaatgacta tattcaatat gttacgtctg actttttggc gggacttggt
    22861 tttggggcta ctcaaatgct aggagaatta gaaggcattt actttggcta taacgtagat
    22921 acggggcgca atgtttacct gaaaccggca ttggcatcac aaggggtcaa aggctcagta
    22981 accaatgctt tggcatctgc tttccttggt tcgttaggtg gggggaaatc ttttagcaac
    23041 aatctcttag tctattatgc cgtccttttt ggtgggcaag ctgtgattgt cgatccaaaa
    23101 ggagaaagag gcggttggaa agaaacgttg ccagaaattg cggatgaaat taatattctt
    23161 aacttgacca gtaagccaga aaatcaaggc ttacttgatc cctatgtgat tatgaagaaa
    23221 aagaaagact cagaaagttt ggcgattgat atcctgacct ttttaacagg gatttccagt
    23281 cgggatgggg agaagttccc tgtgttacgc aaagccattc gaacggttac ccaaagtgat
    23341 cagcgaggat tattacaagt aatcgttgaa ttgcgtaaag aggactcacc agtcgcggaa
    23401 aatatcgcgg atcacatcga gtcctttacc gattatgatt ttgcccattt gcttttctca
    23461 gatggttcga ttacccagtc gattagttta gataagcagt taaatatcat tcaagtagcg
    23521 gatttggttt taccagatgc agaaaccact tttgaagaat ataccaccat ggaattgctg
    23581 agtgtttcca tgctaattgt tatttccact tttgccttgg actttatcca tagcaaccga
    23641 gaaattttca agattgtgga cctggatgag gcttggagtt ttcttcaagt agctcaagga
    23701 aaaacgttat cgaataaatt agtgcgtgct ggtcgggcca tgaatgccgg tgtttacttc
    23761 gtcacgcaaa acagtgatga cttgttggat gaacgtttga agaataatat tgggctaaag
    23821 tttgcatttc gcagtaccga tattcatgaa atcaagaaaa ccttggaatt ctttggatta
    23881 gataaagaag atgaaagtaa tcaaaaatgc atgcgagatt tggaaaatgg gcaatgcttg
    23941 atgcaggatt tgtatggtcg agtaggtgtg gtccaagttc atccagtctt tgaagaactt
    24001 ttccatgctt ttgatacccg tccgccagtt caagagagaa tggagtgagg agatgaaaaa
    24061 gaaacttttt cgtatctttg gaattgtttt aatcagtttg gtcactctga taatactttt
    24121 gagcttagtt ggaacggtag ctgaggcaac aggtctggtt gatgatacag ttggagccgg
    24181 aaatctttat tcccaatatt cacttggtaa ctatcagttg gatttctttg tggatagttc
    24241 gtgggattgg ctgccttgga attggggtga tggcctaggg aagagcgtaa tgtatggact
    24301 ttatgccatt actaatttta tttggacagt tagtctctac ttatcaaatg ccacgggcta
    24361 cgtggttcaa gaagcctata agctggattt catttcagat acggctgaaa gtattgggaa
    24421 gaatatccaa accttagccg gcattaccga aaatggactc cagacctcgg gcttttactt
    24481 tgggtttcta ttattgatga ttttagctct aggagtttat gtggcgtata caggattatt
    24541 aaaacgagaa actaccaaag cagtccgggc tgtcattaat tttgtgatga tttttctact
    24601 ttcgggttcg ttcattgcgt atgcgcccac ctatatcaca aaaatcaatg attttagctc
    24661 agatgtcagc gaagcggctc ttagccttgg aaccgagatt gtcgtgccga attcagaaag
    24721 ccaaggaaag gacagtgtgg atttaatccg agatagcttg ttttccattc aagtccaaca
    24781 accgtggtta ctcttgcaat ttgatgattc caatatagaa gaagttggcg aagatcgtgt
    24841 taacaaaatc ctgtctgtaa gtccagatga aaataaaggc aaggatcggg aagaagcggt
    24901 caaagcggag attgaagata atgacaatgc gaatctcagt attaccaaga ccatgaaccg
    24961 cttagggacc gtggtctttt tggtgttgtt caatattggc atatccttct ttgtctttct
    25021 cctaacaggg attatgttgt tctcgcaaat tctctttatt atctttgcga tgtttttgcc
    25081 gattagtttc ttattgtcca tgttgccgac ttatgagagt ttgggcaaga aggcgattat
    25141 tcgcttgttc aatacgatta tgatgcgagc aggagttact ttggtgatta cgactgcatt
    25201 tagcatctcc acgatgtttt tcaatatttc ggcaacctat ccatttttca tggttgcttt
    25261 tctgcaaatt gtgacctttg ccggtatcta tttcaaattg ggcgacatta tgaatatgtt
    25321 caatctccag agtaatgata gccaatcaat gggaagacgg gtcatgcgaa aaccgcaaat
    25381 gttaatgaat cgaacattgc ggcaactcaa tcgaaatgtg ggacggactt tggcttttgg
    25441 tggtggtgca gcagttggaa ataagttggc aaaggaacaa tcaaaatcca aatttaagcc
    25501 atccggttct tctctacgaa agaattcacg attaccgaac gatcacgaga taccatctga
    25561 cttgaataag gaaaagccaa ttccaaataa taagaaacaa tcccgaatga atttggccgg
    25621 gagaaaagtc ggcaaggttc tggataccca agctttggtg aaagataaga ccaaacaagt
    25681 aaaggatgga gtacggaata cgccaaccaa cttgaaatac aacttccata aaggaattga
    25741 aaaaacgaaa aaagcaccgg aagagtttaa gcgaggactg gtccaagaaa aagcaaatcg
    25801 aggagagttg cgagaaaaac aacaacaacg tagagacgaa aaaatagctg aaaagcgcaa
    25861 agtattgaac gaaataggga atcctcatgg gaaaagaagg gaaaatgttc cgataaaagc
    25921 aaaggtccaa tctcaaaagg atagagcacc aaagcggatt gtgagagcaa attcgaatcc
    25981 cgaaatcaaa cgaaaattcg ctagccaaga aatcatttca aaaggaataa accaatcctc
    26041 aagtaagaaa aattcttttc aacaagtgaa acggcggtct actctgtcca aacgaaccaa
    26101 tcgaaaagta caaaaaagtt tgaaccctca tcccaaacca aggtcaggtg agaaaaaatg
    26161 aacgtaaaga aattaagtgc catttcgtta actttcctaa caatctcttt tatgggtatc
    26221 ttgatgtgtg tgggcttatt gtttggtgaa gacagtgaag gaagtagtag ttcaggtgct
    26281 cctcctgggg ggagtagtgt ctcagaagag gttttgaaac accgtgcaat ggtggaaaaa
    26341 tatgccaaag aatcggatat aacagagtat gttccgattc ttttagcgat tattcaagtg
    26401 gaatctggtg gcacaatgga agatgtgatg caaagttctg agtcagccgg tttaccaccg
    26461 aattcattaa gtaccgaggc atccatcaaa caaggatgtc tctattttgc gtctttggtt
    26521 aagcgttcca aagaattagg ttgtgatcaa gatagtatca ttcaggccta taactttggc
    26581 ggtggttatt tggactatgt ggcaaaaaac gggaagaagc atagttttgc tttagctgaa
    26641 tctttttcaa aggaaaaatc ttgcggtcaa aaaatcgatt accctaatcc catcgcgaat
    26701 aaggaaaatg gtggatggcg ctataactat ggcaatatgt tttattgctt attggtgaag
    26761 caatacctaa ctacaacaca gtttgacgat aaaacagtcc aagggatttt tgacgaggcg
    26821 tttaagtatg aaggaacggc ttatgtattt ggtgggtcaa gacccgaaac aggatttgat
    26881 tgtagtggct tgactcaatg gtgttatgcc aaagttggtc tgaaacttcc tcgggtggct
    26941 caagatcagt atgatgccat gacccatatt gacctaaaag atgccaaacc aggggatttg
    27001 gttttctttc attcgactta tgatgccggt acttatgtga cccatgtcgg tatttatgca
    27061 ggggagaatc gcatgtttca tgcaggagat ccagtaggct ggacgaatct aacagaaagc
    27121 tattggcagc agcatcttat cggtgctgga cggtacaaat aagagaaaag aggaaaaaga
    27181 atgaagataa aaattgaacg gaatcaaaag gaaaagagcc taaaaaagaa aaaagaacga
    27241 gtcgtatccg tgggtaagca tcgaaaaatg gtgcttgccc tttggctttt attatcttgt
    27301 agtcttactt ttggcgttta taaaaatttc accgccattg atcaacatac aactcatgaa
    27361 aaagtggtta ttaaagagaa agtagtgaat acttctggta ttgaaaactt tacgaaggat
    27421 ttttcgaaag aatatttttc gtggaaaaat aacaaagaag caattgaaaa gagaatgaac
    27481 aacctcgaac agtaccttac agaagaaggt ttcgctttaa gtcaagatat ggttcgagca
    27541 gatattccca ctaattccga agttcagtca gtaaaagtct tagatgttga aaagagctcg
    27601 gaggaatttg tcgtttcatt tttagtggag caaaagatta cagagggaaa aaaggcacaa
    27661 tcgatttctt ctgcataccg agtgacgatc tttgaagatg aaaacaggaa ttatatagta
    27721 acgagtttgc caactatgat tgcaaaacct gatagggcaa aatacaagac aaaacaagta
    27781 gaaaatgatt cgaaaattga tgccaaaact acagaagaaa tcgctgagtt tttggaaacg
    27841 ttctttaaat tatatccatc agcttctgaa aaagaattgg agtattatgt tgaaaatgat
    27901 gcgatgcgac caatcaatat tgacttaaag ttttcgaagt tagaggatcc agtttaccta
    27961 caaaacggaa aaaaaattct agtgagtaca aagataaaat accttgataa tgtatcaaaa
    28021 accactagct actttcagta caaattaata ttacaaaaaa atggaaactg gaaaatcatt
    28081 gatgttaaat aataatgact caatctaaat ttatgagaag ttataagtag tttaacttat
    28141 ttcaggcaga agtcgcccat cctctatagg tgggtgatga atgccgttcg gtaactcgaa
    28201 aaccgacaat taagacatag tgccttttta ttttaatcca tgtcataatc agtctatata
    28261 agaaatggtt gatataccat ggaattagat acaaataatc attcattatt tcttctttgt
    28321 taccacctta ttttagtagt gaaacattgt aaacatctca ttgatgatgt aatgttagct
    28381 tatgcaaaaa actatctttg aaagaatatc agaatcacat cacattacct tagttgagtg
    28441 aaatcgtgat aaagactact ttcatattat gctcaaagca caacctaaaa ccgaattaac
    28501 aaaattcagc aatgcctaag ctcatgtctg ataaaatgag actttctaag ggtcaaaaat
    28561 ttcctttgaa tacgatcatt agcttagata aaagtaaaaa ccttagaact acggggatag
    28621 cttggttaat aagagatatc gctgttaata aagacataag cttgcaagta tgctctattc
    28681 ccaagaatct cccacttcaa gcactaagga tcgttaaatt cagctaagtg gcaagtagtt
    28741 cactagacga taattatctc catatttcaa tctcagcttt tccatttttc atagcaaatt
    28801 ccgttatttt tatagcatct aaaagattca gcttttccac tgatctttca ccacttttca
    28861 gcttttttat tgtgcttaaa ttgataccag taccttttga tattgaattg gaagtaaaat
    28921 cattaagggt tttttttatt aaattcatat ccgcaattcc agcgttcata agaatgaaga
    28981 ttctcctctc atagactact ttgaaaatgg tactacagtg gctgtttata tatttcagta
    29041 ggttactgta gtggtcattt tattataatt agaaaaggaa cctaaatcaa aaatgctaaa
    29101 gaaaattttc atagtattaa acctatcatg actaaagcca cggaattctt gataaaagag
    29161 tatacttgca agcctatgtc tttactaaca gcgatatctc ttattaacca atctatcccc
    29221 gttgttccta aggttcttga tgttttctaa ggcaatgctt gtatacatag cccttgatca
    29281 aaatattgat actaacgttg acgtttcgat catgatgtgt acggcaaata ggacaagtcc
    29341 attctcgaat tgtgaatgac ttcttaccat ctgtgtgtcc acattctgaa ccaatttgac
    29401 tagacggaaa tcatttatct atcttgatga tttttttgac agaagtatcg aaaatcttta
    29461 cataatctgg gtgttgcatt cttatgcaga tgagagcgtt agctccgtat tcataaccag
    29521 ttgcctctaa aacgtagtcc atcggtggat acctagcttg cggttgccag tggctttcgc
    29581 agtcttcttg taatcaaatc gagcatctaa ttgagtacta gtattttgaa gataatactt
    29641 gagtttttcg gttttcagaa gttcacttca tcttccatca tccatggaaa tcccactcac
    29701 ccatacgcag gcctccaaaa attcttcaac aatggttttt cagacatttt tctgaatacc
    29761 tccttgtttt ttgatacgcc agatagtcag gaaaaaggca acaaaacaca aaacaaagct
    29821 gcctaaaaag gtaatcttca ttccatataa aaagacatcc ggccgatctg cgatatagtt
    29881 agttactcgt tggcccatct tagcagacat cgcttgatat aagaccgtcg tagaaagcga
    29941 aatcccgatg accatcccca aatttcgggc aaaggaattc atggagcctg ccagtcccaa
    30001 attttcgata gtgacagaac tcataaccat cgtattattt ggggactgga acaaggcatt
    30061 gccggcaccc atgatggcag tagcgacaat gtacagccac aaaggagagt ccactgacaa
    30121 aaacatatac atgacttggg ttaccgacaa taaacccaag cctactaata caaaaatctc
    30181 cgggccaacc cggtcggtca ggtatccgct taaaggcgcc ccgacgacca tcatcaaggg
    30241 aaagaccatc atcaacagtc cggcatagct aggactcaac ccgcgagcat tttgcagata
    30301 aaaaggaatc actacattaa caaagaagtt ggaagaaaaa atcaacaagg ctgtaatcaa
    30361 gctcatggta aaaatcttgt tcttaaaaat accgaaagaa atcaatggag aggctgcttt
    30421 cttttcaact tttaaaaagc tgacaaaggc aatcactgaa attacgaaca gtacaagggg
    30481 gactggatgg aaaaagccac tttcttgccc caaaaagatt gttccaaaaa ggctgataat
    30541 cgtagccgca atggcagcaa agccccctcc atcgattgta tggccgctca tggtgatatc
    30601 ttttggtaag aatttttcag caatcaacat cgttacgatt cccaccggta cattgatcca
    30661 aaaaatgtac gcccaagaaa attgggacaa aatcaagccg ccaagacctg gtccagcaat
    30721 cgagcctaat gaaacaagcg caccgattgc tcccaatgcc cgaccacgtt catgtatggg
    30781 aaagacttcc gtgatgattc cggcatttgt agccatagtc atactagcac caatggcttg
    30841 taccacccgt gcgaacaatt aaatacctag cgaatgattg aacccacaca acagcgagcc
    30901 caagacaaag atcagcgtac caatccgaaa tactttgatt ttcccacagc tatcgccaat
    30961 tttaccaaac agcaacaaac aagaacagac aatcatcaga taaacggaca ctacccattc
    31021 cgcttgattc attggtatgc ccatatcatc tgagatggta ggtagtgcaa tattgacaat
    31081 actgccatcc aatgtggaca tgaaggtaaa catagatata gcaatcaaaa tccaccagcg
    31141 atttttttgg acttttgcat cttcttgata actatgcata ataggatttc ctttctaatg
    31201 atcgtgtagc taagaacaat ataacctatg tctactgccc aacaacttct cgcgactcta
    31261 gccataggaa gcttgagtaa tttcgatttg ttattctcat gtaaccatgt aagtttgaga
    31321 tgctttattt gaacttactc tatagtaact agtgataatt cgctttactt tcttctagca
    31381 atttctaaaa gtcgacttca ttgttcttca gattaatagt gtgagctatc tcgtgagacg
    31441 taagaaaatt tccattctac tttttcccaa ttttttcata tttatggtgt tgcacctatt
    31501 tgttttccaa tttgcttttc aaatacattg ctatgatatt caattccata ggattatact
    31561 aaatgtcaat agtatgaata atatattata gatgtttata tatcactgtt aattattatc
    31621 cacaataatt aatgattacc tcgatatttg tcaatcaaag gttgaaacaa tttattttca
    31681 gcatcttttc taacttgagc tgcactctta atagaatcat acgatcctaa atagtacctc
    31741 ttttttttaa agttatatac gcaatccatt tctctttaga acgataaact cccttaacac
    31801 cacttgtatt atttttcggt aattttgacg ttagacactc tattactgtc ccttcaacac
    31861 atgtccttgt ttcttgcctt tttaaacatc cacaactttg agtatgtcca aaaaataagt
    31921 tactataact tatctcacac atactgccac actcacattg acaaacccat tttgttttcc
    31981 atgaacagtt attgtccaaa ggatactttg cagtaagtaa tccgaatttt ttattttcaa
    32041 tgtgatgctt ttttgatttc aaacatccac agctttttac atcacctttt agaagtcgct
    32101 ttgccgatac taactttttt ctcccacaca gacattgaca ttcccaaaca acagttcctt
    32161 cacttcgcag tttagttggc ttgattgcaa ctaacttacc aaaagtttta tttgtcaaat
    32221 ttttatattt atgcctattt ttataatttc cacatccaca acttttggtt ctacctgata
    32281 gtaagtttga tcgatataca atcgtttcat tcccacagtc acataggtaa cgatattttt
    32341 tatatccatt atgagtaatc tcctcaacaa cagtaaggtg accatatctt tccttcactg
    32401 cacctaccct cccaagaaag aagtaccata taatttcaat taacttttaa taaatcagaa
    32461 aaaaatattt tcaatttttc ttagtctgat tttatgacta atttataata caagactgaa
    32521 cgatacgtac acgaaatcct caagatagat aaattgtttt catctagtaa aacctgctca
    32581 aaatatgagc ataaagacgg caataataca ctcgatattc gataatggac ttgttttatt
    32641 tgtcaaactc atcgtaatcg agatatcaat tccagtctca atatcctgat caaaggtcta
    32701 agaatccaac cattttcttg ttactttgtc agattgatta ccttttttag tctccgaata
    32761 ataaggtttt cggatcaact aacatgctct gagaaagact actatctttg caaatttcca
    32821 aatgaaggtg tgggccagta ctattcccag tacttcctac atagccaatt atttgtcctt
    32881 gcaaaacatt atctccagtt tttactaggt attgttgctg gtgagcatat aacgcggttg
    32941 atccatcttc gtgttgtatc accacgtaat ttccccaaga gtagtgaaac tctgctttaa
    33001 caaccttacc agctttaact gcatgaatcg gctcaccctg tgtagctgcc atatcaagtc
    33061 ctcggtgaaa ttcatttcca cgatttccaa acaaactggt tattgaataa ttatgaatag
    33121 gcacttggta tccagtctta ctcatttgtg gacctttaac ttctttatca tagttggtta
    33181 aatcataggt tttaattaat tcatttagct tcaaatagta ttgtgtatct gttgcatacc
    33241 gtcctgtaag gaatttagtt gcttctcgat atgttttact attagctttt aatgctcctg
    33301 cataaaaatc tttatttcca ctaattccct tagttaataa tttggcataa tcttcaaaac
    33361 tttcctcata gttttcatac actctaaatt ttgattgggt cgtataaagc gttccattac
    33421 ccaaatcttc gtttgttacc ataatgacaa agtttccatt ataagttcct tttatcccaa
    33481 ataaattgta attcggtgcc tgagctaact ggctttgacc actggcagat tctaagatcg
    33541 cttgtgcaat cataacagaa gcatataaat catatttctg accaattttt ctcgcagact
    33601 caccaatttt cataataaaa ttttctacag attcattttt gtcaaaatga atttcttcat
    33661 taccagatag tattggttgt gattggaaag attctgttga ttctatttgc tgtggtgtcg
    33721 aaaaattttt tgtttgtcct tccgtttttg gcgcttcctt ttttgaagac tctatatggt
    33781 ttggtcttgt cactttcgaa gaagttattt cacttgtact acttgaagtt gttgaagatt
    33841 cggcacttga aatcgtacta ctttcacttg acgaagttgt tgaagactcg gcatttgaag
    33901 tcgtactact ttcacttgac gaagttgttg aagactcggc atttgaagtc gtactacttt
    33961 cacttgatga agttgttgaa gactcagcat ttgaagtcgt actactttca cttgataaag
    34021 ttgtcaaaag ttcactactc tctgctgtta catcggaatt actcatttca gtcgtctcgg
    34081 ttctttcttt tgcaattttg tatgttgaat tttcgcttgc caacacatgg aaaggtgttg
    34141 ctataaagag ttgggacatt aatataactg ctgatgcaag ttttaaagat tttttcattt
    34201 gatttacctc tcttttttct ctttaatagt gttttctatt aaaaattatg ataaatattt
    34261 tcaatgaatt gagtaataca gtatatttct tgatttcatt tagtaacgat tatgtttcaa
    34321 tgtttaatcc tgttactgcc tttaaaataa aattataggg ttggctaaaa ctaggatgaa
    34381 ataaataatc taacattttc aatttgtcta atgtaatttg ttcttctata gcaagagaaa
    34441 acattgataa tagtccagat aaatcttctt gactacaaag ttgtacacct actattctct
    34501 ttgtattttt ttcaaagcta attcttaatt ttacacgact attttttctc aaaaaaacag
    34561 gtctaatgaa atcttctatt tctatataat ctatagactc acttaataat cgtgctgttt
    34621 ttaaattcaa acctgctgcg taaaaattgt aattaaatat agaaaagcca tttgtaaatt
    34681 gggaaccaga aggtgtaaaa tcttgattgt caatatgttg agttgcaata taagctgttc
    34741 ttagagcatt agaaatagaa aaatcaacac tacttctatt aatggacgta aaaaaagttg
    34801 tagcacaatc cccaatagca tatatatctt ttatatttgt ttgctggtat tcattagtta
    34861 gatatgctcc actaacatct ctcaagagtt cctttttgcc aattggacta ttagatagaa
    34921 atcctatagc ttgtacgacc atatccatag agtattgggt accacttgta gtgactattt
    34981 tttcaatctt ttttcttcct aaatattttt taggactttc tgatagacaa agatgtattc
    35041 cattttttga tagtatttct tcaactttat ctgaaaaact acggtcgtaa taagtcgaca
    35101 acactctatc tgcaacatcg aaaagatata cttctttccc tctttttctt atggcttcag
    35161 caatttcaac tccaatatat cctgctccaa taattcctac ttttttaata gtattatcat
    35221 ctaaagcttt aaaaatctct ttagcatttg gaaaattctt tatcgaaaaa atattagcta
    35281 aattattccc cggtacatct aacataattt gctttgaacc tgtagctagt ataagtttgt
    35341 catattcttg ggaaaatctt gtgccatctt tttttacaca aataatcttt ttattttgaa
    35401 tatcaatttt gtcaactgct gtctccaaaa acaacttttt tatcttagaa tttagttctc
    35461 ttctattttg ataaaaaaga tcttctaaat tgctaacttc tctttttatg aacaacgatg
    35521 tcccacattc taagtaacta atttctgatt ttttatctat cagaataact tcataatttg
    35581 aatcacataa gtttagaaat cgagctgcag ctagccccga atggtttgat ccaataatta
    35641 ctattttttt cacttaatca cattcttttc ccttctatga aaagtatctt catttttaac
    35701 taacaaccta tctcccaaaa taaaaaacaa aaagaggaag aaaaagattc ttcctctttt
    35761 cagagaagat ttaagaaatt gattttctat tcattctctt tttttcgatt tttataccct
    35821 aataacccta aagttcctaa caggattaaa ccaccactaa tagtaaagat attactatca
    35881 atctctcccg tcttaggata agcttttgag gactgctttt gaggactgct tttgcctcta
    35941 tttttgtttt gcttgctacc ttgattgtca gtcttattat ctttactaac ggctttttca
    36001 ctgtcttttt cgtttgaaga aacaactaca ttagtaggtt cactagtatt accagattca
    36061 tcagttgcag ttactatcac ttttgttcct gcctctaatt taggaacttt aactgtaaaa
    36121 ttaccatttt tatcagctgt cccatggtat tgactcccgt ttggtaatgt aactgtcacc
    36181 tctgcatttg gttcagtttt accag
//
LOCUS       DACBYO010000022        34656 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.022, whole genome shotgun sequence.
ACCESSION   DACBYO010000022 DACBYO010000000
VERSION     DACBYO010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.022"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            156..1862
                     /locus_tag="IVD26_001041"
     CDS             156..1862
                     /locus_tag="IVD26_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAP6079032.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="IVD26_001042"
     CDS             complement(2020..2922)
                     /locus_tag="IVD26_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6079033.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3623)
                     /locus_tag="IVD26_001043"
     CDS             complement(2919..3623)
                     /locus_tag="IVD26_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAP6079034.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="IVD26_001044"
     CDS             complement(3654..4295)
                     /locus_tag="IVD26_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP6079035.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="IVD26_001045"
     CDS             complement(4333..4647)
                     /locus_tag="IVD26_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079036.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5264)
                     /locus_tag="IVD26_001046"
     CDS             complement(4635..5264)
                     /locus_tag="IVD26_001046"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAP6079037.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="IVD26_001047"
     CDS             complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="IVD26_001047"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAP6079038.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5984..6916)
                     /locus_tag="IVD26_001048"
     CDS             complement(5984..6916)
                     /locus_tag="IVD26_001048"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAP6079039.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="IVD26_001049"
     CDS             complement(6913..7689)
                     /locus_tag="IVD26_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAP6079040.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="IVD26_001050"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="IVD26_001050"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAP6079041.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="IVD26_001051"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="IVD26_001051"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAP6079042.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="IVD26_001052"
     CDS             complement(12014..13294)
                     /locus_tag="IVD26_001052"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAP6079043.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="IVD26_001053"
     CDS             complement(13313..14239)
                     /locus_tag="IVD26_001053"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAP6079044.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="IVD26_001054"
     CDS             complement(14252..15535)
                     /locus_tag="IVD26_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAP6079045.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="IVD26_001055"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="IVD26_001055"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAP6079046.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="IVD26_001056"
     CDS             complement(16323..17234)
                     /locus_tag="IVD26_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP6079047.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="IVD26_001057"
     CDS             complement(17231..17695)
                     /locus_tag="IVD26_001057"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAP6079048.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="IVD26_001058"
     CDS             complement(17700..18398)
                     /locus_tag="IVD26_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP6079049.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="IVD26_001059"
     CDS             complement(18385..18771)
                     /locus_tag="IVD26_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079050.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="IVD26_001060"
     CDS             complement(18918..20588)
                     /locus_tag="IVD26_001060"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAP6079051.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="IVD26_001061"
     CDS             20771..21004
                     /locus_tag="IVD26_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAP6079052.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="IVD26_001062"
     CDS             complement(21103..21534)
                     /locus_tag="IVD26_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAP6079053.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="IVD26_001063"
     CDS             21613..22026
                     /locus_tag="IVD26_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAP6079054.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="IVD26_001064"
     CDS             complement(22064..23212)
                     /locus_tag="IVD26_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP6079055.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="IVD26_001065"
     CDS             complement(23334..23930)
                     /locus_tag="IVD26_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP6079056.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="IVD26_001066"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="IVD26_001066"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAP6079057.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="IVD26_001067"
     CDS             27160..27591
                     /locus_tag="IVD26_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6079058.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="IVD26_001068"
     CDS             complement(27636..28985)
                     /locus_tag="IVD26_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP6079059.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="IVD26_001069"
     CDS             complement(29055..30218)
                     /locus_tag="IVD26_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079060.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="IVD26_001070"
     CDS             30347..30670
                     /locus_tag="IVD26_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079061.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="IVD26_001071"
     CDS             complement(30853..32202)
                     /locus_tag="IVD26_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6079062.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="IVD26_001072"
     CDS             complement(32271..33224)
                     /locus_tag="IVD26_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAP6079063.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="IVD26_001073"
     CDS             complement(33326..34516)
                     /locus_tag="IVD26_001073"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAP6079064.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9847 a         7592 c         6087 g        11130 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaac ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttaca
//
LOCUS       DACBYO010000023        34385 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.023, whole genome shotgun sequence.
ACCESSION   DACBYO010000023 DACBYO010000000
VERSION     DACBYO010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.023"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            61..219
                     /locus_tag="IVD26_001074"
     CDS             61..219
                     /locus_tag="IVD26_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6079065.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            291..1517
                     /locus_tag="IVD26_001075"
     CDS             291..1517
                     /locus_tag="IVD26_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6079066.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGIASEKYQKVFPTRQLAIKA
                     EREMKKKIETVLREENANSLELKGKIKFKDFYESKWLPRYELGQTTRSNRAPSNVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILCYIEFNRTTKIIQCITAPKKMALEEKRIREGNQALSSEELTDWIEAVNNDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFNKNTVRLKYALDKYQRKTHTKGWKDTV
                     IQAPEVVMTLLREWKSAQAEQLLKLKIIQTPDQYLFTYSKPSGEVNCPVHADYLNYRI
                     NAIKKRHPELAQLSPHKLRHTYATIAREGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKSVFEAFQKGLNKCD"
     gene            complement(1606..1998)
                     /gene="rpsI"
                     /locus_tag="IVD26_001076"
     CDS             complement(1606..1998)
                     /gene="rpsI"
                     /locus_tag="IVD26_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP6079067.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(2014..2457)
                     /gene="rplM"
                     /locus_tag="IVD26_001077"
     CDS             complement(2014..2457)
                     /gene="rplM"
                     /locus_tag="IVD26_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAP6079068.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(2976..3443)
                     /locus_tag="IVD26_001078"
     CDS             complement(2976..3443)
                     /locus_tag="IVD26_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAP6079069.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(3563..5101)
                     /locus_tag="IVD26_001079"
     CDS             complement(3563..5101)
                     /locus_tag="IVD26_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAP6079070.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            5181..5867
                     /locus_tag="IVD26_001080"
     CDS             5181..5867
                     /locus_tag="IVD26_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAP6079071.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(6068..6595)
                     /gene="msrA"
                     /locus_tag="IVD26_001081"
     CDS             complement(6068..6595)
                     /gene="msrA"
                     /locus_tag="IVD26_001081"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP6079072.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(6679..7356)
                     /gene="pgmB"
                     /locus_tag="IVD26_001082"
     CDS             complement(6679..7356)
                     /gene="pgmB"
                     /locus_tag="IVD26_001082"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP6079073.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(7353..8481)
                     /locus_tag="IVD26_001083"
                     /pseudo
     CDS             complement(7353..8481)
                     /locus_tag="IVD26_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(8481..10664)
                     /locus_tag="IVD26_001084"
     CDS             complement(8481..10664)
                     /locus_tag="IVD26_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAP6079074.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(10661..11686)
                     /locus_tag="IVD26_001085"
     CDS             complement(10661..11686)
                     /locus_tag="IVD26_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6079075.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(11731..12558)
                     /locus_tag="IVD26_001086"
     CDS             complement(11731..12558)
                     /locus_tag="IVD26_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP6079076.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(12555..13622)
                     /locus_tag="IVD26_001087"
     CDS             complement(12555..13622)
                     /locus_tag="IVD26_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAP6079077.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(13648..14484)
                     /locus_tag="IVD26_001088"
     CDS             complement(13648..14484)
                     /locus_tag="IVD26_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6079078.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(14481..15350)
                     /locus_tag="IVD26_001089"
     CDS             complement(14481..15350)
                     /locus_tag="IVD26_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6079079.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(15420..16703)
                     /locus_tag="IVD26_001090"
                     /pseudo
     CDS             complement(15420..16703)
                     /locus_tag="IVD26_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
     gene            complement(16717..18402)
                     /locus_tag="IVD26_001091"
     CDS             complement(16717..18402)
                     /locus_tag="IVD26_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAP6079080.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            18677..19702
                     /locus_tag="IVD26_001092"
     CDS             18677..19702
                     /locus_tag="IVD26_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6079081.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(20297..23950)
                     /gene="rpoC"
                     /locus_tag="IVD26_001093"
     CDS             complement(20297..23950)
                     /gene="rpoC"
                     /locus_tag="IVD26_001093"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAP6079082.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(24029..27646)
                     /gene="rpoB"
                     /locus_tag="IVD26_001094"
     CDS             complement(24029..27646)
                     /gene="rpoB"
                     /locus_tag="IVD26_001094"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP6079083.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            28374..29342
                     /locus_tag="IVD26_001095"
     CDS             28374..29342
                     /locus_tag="IVD26_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6079084.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            29360..30265
                     /locus_tag="IVD26_001096"
     CDS             29360..30265
                     /locus_tag="IVD26_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079085.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            30262..31068
                     /locus_tag="IVD26_001097"
     CDS             30262..31068
                     /locus_tag="IVD26_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6079086.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            31225..32193
                     /locus_tag="IVD26_001098"
     CDS             31225..32193
                     /locus_tag="IVD26_001098"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAP6079087.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(32510..33034)
                     /locus_tag="IVD26_001099"
     CDS             complement(32510..33034)
                     /locus_tag="IVD26_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAP6079088.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            33321..>34385
                     /gene="scm"
                     /locus_tag="IVD26_001100"
     CDS             33321..>34385
                     /gene="scm"
                     /locus_tag="IVD26_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAP6079089.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT         9821 a         7305 c         6445 g        10814 t
ORIGIN      
        1 gcggttcaaa aattttaaac tattatttta ggagatgatt ttataaaatc gaaagcctac
       61 ttgaataaaa aacaagcctg tgaatttcta ggaattgata ataatacttt agataagtgg
      121 attcgtgtat ataattttcc agtaataaaa attgatggcg tagttcgctt tgacgtagag
      181 gatatcaaag atttcatgaa tacattcaaa aaaaattgaa attttcttct cgtcacatat
      241 actataaata gcgaaatgta ctgccttact ttttaaagga gtgaggaagt ttgcctacaa
      301 agctttcaaa tgggaaatat aaaactaatc tgaggtatcc aaaaaaattc agagaaatca
      361 ctggaattgc atcagagaag tatcaaaaag tatttccaac taggcaatta gctattaagg
      421 ccgaaaggga aatgaaaaag aagattgaaa cagttttaag agaggagaat gcaaactcac
      481 tagaattgaa aggaaaaata aaatttaaag atttttatga atcaaaatgg cttcctagat
      541 atgaactagg tcaaactact aggtcaaaca gggctccaag taatgtaaca attagtaata
      601 ctaaggatat attccgattg cacatccttc caatgtttgg tgaatatgca atgaattatc
      661 tgaattcaaa tactgagata atatcagatg aattaacaaa gaaatcgaaa gaatacgcaa
      721 atataaaaat tatcaaaggc tatgttcgct ctatgtttga tattgccgaa atactatgtt
      781 atatcgaatt caaccgaact accaaaatta ttcaatgtat taccgcgcct aagaaaatgg
      841 ctttagaaga aaaaaggata agggaaggga atcaagcatt atcatcagaa gagctgactg
      901 attggataga agcagtaaac aatgacttaa ataatcactt gcttacactt cacgattaca
      961 cacttttcat gcttacctta tatctaggtg atagaaaaag tgagacttat gctctgcaat
     1021 ggaaatatat tgattttaat aaaaatacgg ttcgtctcaa atatgcttta gataaatatc
     1081 aaagaaagac acatacaaaa ggttggaaag acaccgttat tcaggcacca gaagttgtga
     1141 tgacattatt aagagaatgg aaatcagctc aggctgaaca attgttgaaa ctaaaaatta
     1201 tacaaacacc tgaccagtac ctctttacct attccaaacc ttctggagaa gtaaattgtc
     1261 ctgttcacgc tgactactta aactatcgaa tcaatgcaat aaaaaaaagg catcctgaat
     1321 tggctcaatt atctccacac aaacttcgtc atacctatgc aactatagct agggaaggtg
     1381 gagcaaatat gaatcaaatc tctaatgctt taacgcactc ggatatttct actacaaaaa
     1441 tatacgtgaa cacacctgac gtagttgata aatctgtttt tgaagcattt caaaaaggat
     1501 tgaataagtg tgattaacat gtgttctcaa atgtgttctt attataaaaa aagacacttt
     1561 ccaaataatt gaaaagtgtc ctgaaatatt gatataaaaa gaatattaac gttttgagaa
     1621 ttgtgaagct ttacgagctt ttttaagacc tggtttttta cgttcgacca tacgtgcgtc
     1681 acgagtaagt aagccagcac gtttaagagc taaacggaag tcaggatcaa cttctagcaa
     1741 tgcacgagcg ataccatgac ggatagctcc tgattgtcca gcgtatcctc cgccgtttac
     1801 gttaacaaat acgtcatatg cgccttttgt ttcagtaaca gcgaaaggtt gattgattac
     1861 ttcacgcaag tcagcatgtg gaatgtattc ttcaacatct tttttattta cagtaatttt
     1921 gccagttcct ggtactagac gtacgcgagc aactgcgttt ttacgacggc ctgtgccgat
     1981 atattgaact tgtgccaatg aaattccctc ctattagatt aagtttgtga tgtctaaaac
     2041 ttctggttgt tgtgctgcat gtggatgttc tgctccaccg tatacgttca attttgtaaa
     2101 ttgtttgcgg cctaaagtgt ttttaggaag catacctttt acagaagttt cgatcaaacg
     2161 acgagaattt ttagcacgca attcgccagc agtgattgat ttcaatcctc ctgggtagtt
     2221 gctgtgacgg taataaattt tgtcagtcgc ttttttacct gttaatttca ctttgtctgc
     2281 attgatgacg atgacgaaat cgccagtatc caaatgaggt gtgaaagttg gtttattttt
     2341 accacgtagt acagatgcaa caactgttga aagacgtccc aatggaacat cagttgcgtc
     2401 tactacatac catttacgtt ctacttcgcc tggtttggcc atatatgttg tacgcacgtt
     2461 attttcctcc aatttaagtt ctgatgtttg acatacactt cgagtttccg gggctctttg
     2521 tggggcaaac aataccattt aacatattac ccgctaatct agtcaatgtc aacgtttttc
     2581 tgcttgattg aaaaatttat atgaaacttt acttcttttc tttcttttat ataaaagggt
     2641 cgtttcctgt caaaatgaaa aacaaaaaga ggctgtgaca aaagtcttgt cacaacccct
     2701 tattttgaat aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatccataa
     2761 aacataagaa gctgtttttt aaaattgttt cttgtgactc ggagctgaac ggcaggctta
     2821 caacctcttg gtaaacggtg ttcaatcagc tgaccctcgg tattagctca aaaaacggca
     2881 aaatatgagg aactattttg acgtttgttt ctctaatact caggtcaaaa cgctgatttc
     2941 acaacctctt tttcggtcaa gttcaacaac agtttttacg cgtcgatctc tggcgctttg
     3001 cccaaatgag cttggatcat ccagatacgt ttttctgtgg ctgttttgaa ttcgataaag
     3061 atatcttgtg ttggatcgtc gccttcttct ccagaaactt cgattccttt ttggtaaaga
     3121 tctgctagat aacgatagcc tgcaacaagt gtttccaaac gttctggaat agtacgatcc
     3181 cagcggccaa tttcatcagg gatttttgtg ttatctgcaa attcacgcaa tgtagaataa
     3241 ggtgaaccgt ctaatgtgat caagcgttcg gatacttcat ctaactgagc gttcaaatca
     3301 tccatgaact catccatcat tgggtgcaat gtaaggaaac ctggtcctct catgtaccaa
     3361 tgtgtttggt gaacaacaac agacatttgg cttagatctg caactaattg atttaatact
     3421 tctttggttt gttggaattt catctttctt gcctcctaac attttcttac acttaaaata
     3481 atagtagact ttcaatgaaa agtacaacaa aatcatttac ctgagaacga ttttcagttc
     3541 gcttttttat ccgtaaagcc aatcattttt cagaatcagc taattcttct cgcagttgag
     3601 caaattgctg ataagtctgt gctaaatgct tttgtgtcga aacaaataat ggatagattt
     3661 tctgatattt tttatgatca gtttcttgta ctccaacttg ctctttcaat tctatcaatt
     3721 cctgtgcttc actgatactt tggatctttc cgatgcttct ccagcctaaa atcacagctc
     3781 ctaatgcgga tgcttctgtg acagtaggga aaacaagcgg gtaacccagt acatcagcca
     3841 tcatctgacg aaaaatcgga gattgagcaa acccgcctgt agcacggatc tctgtgagct
     3901 gattttcctg gcaaactcct tttaaaatcc gataaaggtt gagacagatc ccttctagaa
     3961 tcgccttcat catttctttt tctgtatgtt gccgctgtaa accgataaaa ctgccaaacg
     4021 catctgcgtc ccaaagcggt gctcgctcac caagtaaata gggatgaaaa atcagaccat
     4081 tggcacccgc tggcacaaaa gcgatagccg aaagcagtgc atcatatgga ttttctcctt
     4141 tttctttagc agattgaacg acttcctgta aaaatgtatg ccctgcccaa tcaaagatgc
     4201 cagcaccatt gctagtcgct cctcccacta cccaatgttt ctgatccaga acataacaaa
     4261 acgtctccat ttctggatgg aactgaggct gagtagtaat aaaacgaagt gctccgctcg
     4321 ttcctacggt caaagcggcg atcgtatcac caaaagcacc taaccctaga ttagaaagcg
     4381 gcccgtctgc ccctcccaaa acaaatgata tatcatttgg caaacctagt tctgctgctg
     4441 tttttgatgg tagacctgtt acttgatagg tggaaggaaa gacttgcggc aattgctcta
     4501 ttcgaatgtt caagtagtca agcacttctt ctgcccattg gaattcatgg atatcaaaat
     4561 atccagttcc tgaagctgtt ccgtagtcgc tgatcagttc gccaaacaat ctataaaaga
     4621 tatagtcttt gataccgaca aaataagcag tttttttgaa taattcaggt tggctgtttt
     4681 gcagccactt gattttgttc aatggtgtca ttggatgaat cggcgtccca gtctgccgat
     4741 aaaattcttt gccaagcacg gtatatttca gtttttctgc ttcgtccgct gctcggttat
     4801 ctgcccaagt gatcattcga gataacggtg ttttctcttc atccaacaat atcaggccat
     4861 gcatcgcaga ggagaaggag acaaattgaa tgattgtgtc tgaaggcaac tgtttaatta
     4921 cttcttttat aacggtgcag acaccttgaa agatcaattc ctgatcttgt tctgccatcc
     4981 cttgtgtttc ttggatcaaa gggtagcgaa aataagcgga tgctgcttct tgggcttcat
     5041 ctgtgaaagc aactgctttg gtttgtgtgg ttccgatatc taatccgatt gaaacgttca
     5101 ttttttcacc tcaaatttta tgtatgtaca aaaatttagt ttaagcttgc gtatcttggt
     5161 tttgaaaagg gggagatggc gtgttacttt attttatcat tggttgctgt atcggatcat
     5221 ttttatgttt aaccgcccag cggattccgt taggtcactc tattatttat cctagatctc
     5281 attgtgtcaa atgctgtcgt tcgctttctt ggtatgaatt gattccgatt ctctcgatca
     5341 tcgtccaacg atttcgctgc cgctattgca ggtgtcggtt gcccttctac tatttgttgg
     5401 cagaagcctt atgtggtggt ctttttgcct ggttctttac tttttcttcc gcaagaaatt
     5461 tttcgacgtt catatggatg ctttcggctt tgctattttc gttgatggat ttattttact
     5521 tcatggtcca ttctcacacg ctattctgtt cttgggcaat tttatggatt ttttggttgc
     5581 aggccggcgt cttccaatgg caaagtgtgc tgttaacgtt tatcgtaggc ggtgtgtgcc
     5641 ttcgctatgg tcaatcctat ctcggagctg gcgatactct gttgatgctt tcttggagtg
     5701 gtggcttgtc tctagaagag ttgcttcaga tcttgtttct tgctagtctg tttggaatat
     5761 ccgttttttc tgtttacttt atctgtcata aaaaaaagtt ggaaaagctg cctttcattc
     5821 cttttttgag cagtgcgttg ctgattgtcc ttcatcttag gtattgaaaa aaggttgtga
     5881 caaacgactt gtcacaacct ctgatatata gtgttctctt accaaatcct tgtgacttgg
     5941 agctaggcga caggttcaca acctctccac taaatggtgt tcaatcagct gaccctcagt
     6001 attagctcaa aatgctggtt ttacaacctc tgatatacgg tgttccataa gtagcttttt
     6061 cggcttctta tttcttgacg ccccaatgtc gacgaaggaa acctgcacgt ccagaacctt
     6121 ctcgataaag attgtaatgg agcttgtttt tcttgtaata atcctgatgg taatcttctg
     6181 caggataaaa ttcgcttctt ggttcgattt ttgtcacgat tggcttatcg aatcgcccgc
     6241 tgtcttgcaa tgcttgtttt gaacgctctg caatatttcg ttcttcttca tcattatagt
     6301 agatcactgg acgataagaa tcaccgcgat cagcgaactg tcctaatgcg tcagtcggat
     6361 cggtttgctg ccaatagatt tccaccaact gatcataaga aataacttct ggatcatatt
     6421 cgatctctac tgcttctgta tgccctgttg tgcctgttgt tacttgttca taagttggat
     6481 ttggtacatg cccgccagta taaccggatg tcacagaaat gatccctggc tgctcttcaa
     6541 atggtttgac catacaccaa aagcatccgc ctgcgaaaac tgcttttttt gtcatataaa
     6601 atcccccttt tttctcatca taccttgatt tccaaaagga ggataacgtt ttgcttgtga
     6661 cagaaaaaac ggaaactatt atatacgtga tacggcttct gataaatgcc aaaacgaacg
     6721 tacttgatca aaaacggtta aatcaggaat cacatattca gcagaaggaa gatttatgtt
     6781 ttcacctatt cccaatacat gcatgttacc agccaaagct gcttgacaac cagcttctga
     6841 atcttcaatg accaagcatg catttggcgg tacattcaat tgctgtgctc ctttgagaaa
     6901 aacttctgga tcaggttttg cttttgatac ttgcgtgccg tcaataagga catcaaaata
     6961 acttgtcaaa ttcgtttttt ctaaaatgag gcgtgcattt ttgcttgctg atcccaatcc
     7021 gatcttgatg tttgtttttt tcaagtactc aagaacagct attgcaccag gcaaaacgga
     7081 tgtttcatcc attttttgaa tcgcttgaag atatagattg tttttttgct cagcaaaggc
     7141 tgatttctct ttttctgaga atttctgttc catttttcca aatgacagca atcgctctag
     7201 tgactcggtt ctggatattc ctttcagttg ctcgttttct ttctcagtga atggaatgga
     7261 cagctggtta gctaaaacca gccacgcttc gtaatgataa cgagctgtgt ctacaagaac
     7321 gccatctaaa tcgaatagtg ctgctttgat tttcatcgat tacctccttg aaaatgaacg
     7381 acttgaagta aagatgcgat gtttttagct gtgcgatgaa gattatcagt ggcttgctgt
     7441 aaagcttctt gtaaaggcac agctgcagga aggatcggaa aaacggccga aatgccaaca
     7501 tctgctgctt tttcgcttcc tttaccaaca cttccgcaaa tagctatcac aggaacgccc
     7561 tctggtactc ttctagcaat cccaactggc gcttttcctt ttagactttg tccatctaga
     7621 cgtccttcgc ctacgattac gaggtctgct tgctgtaccc gtatcgaact ccagtaaatc
     7681 caatacgtag tcgatgccag agactatttt ccctgaagca aatgctaaca gtcctgcacc
     7741 cattccacca ccagcactac tgcccgatgc ctcgattact tgaggggcaa atctcatata
     7801 aaaatcatgc atggcttggt cagccactgc taattcattt tctttcaagc ctttttgtgg
     7861 tccgaaaaca aaagaagcgc cttcttttcc gcataaaaga ttagtaacat cagtaatgac
     7921 agtgattttg gctttaatca gctcaatagg cacgttcgtt ttatcaactg tagcaatttt
     7981 acctagattt tctcccagtg cttctacttt ttgattatct tgatcgtaaa aagcataacc
     8041 tagaccttct gccatgccga tgccgccatc gttggtacta cttccgccaa cgccgatgat
     8101 gatgtgtcga acaccttgtt gcaacaattg tcgtatcagt tctcctactc ctcgcgtgga
     8161 taacctaagt ggctgttgtt ggtttagtgg gacatctttc aatccgacga tttctgccat
     8221 ttcaaaaatc gcagtttgac cgtctgaagc gtactggatt tctttgtttt tgccaaatgc
     8281 attagtaacg actgctgttt gccgcttcaa ccttaaactg tctgctaatg atgaaaccgt
     8341 tccttctcct ccatcgccta taggtagcag atcatattca gcctgaacaa aaacttcttg
     8401 aaaacctgat tgaatggctt gtgctgcctc taaggctgtc agactttctt tgaaagaatc
     8461 tggcgcaatc agaatacgca ttattttccc ctccgttcca agatcagttc tttttccagc
     8521 tggtattggt ctccattgac aaaaataggt aatgtttctt tcgtctcttt ttttattact
     8581 atttgttttt ttgtcaaaac aaatagcaac ctgtgatttt tccaaataaa aggaaaagaa
     8641 attttttccc atgctgaagg aagtcttgga gaaatagaaa gagttccatt cgttactgta
     8701 atacctgaaa aaccaaatat aactgctagc catagtgctc ctaatgaagc agcatgaatt
     8761 ccgtcatctg atgaatgcgg atctggtcct aaatcaatca ggcacgcttc ttggaataaa
     8821 tgatacgccc attccatttc ttggatacgg caagcctcta tggcgtgaat cgctttactc
     8881 aacgatgagt cgtggattgt tttgttttca tagtaatgca aattcttaga aacgattggt
     8941 tgagaaaaat actcaggtaa taagtataac agcatgacaa gatctgcttg cttgctgact
     9001 tggagttcat ttacttcgct acgggcataa tcaagtaaaa tagactggct gccaggacgt
     9061 tctttgtaag tggtcaaatc aataactggc ttactgagat acgtgtcatc ttgcggaatc
     9121 agctgttctt tgttaggcac tggcaaatat aacttatcta aaaaattttg acattctttc
     9181 aaaaaaagcg gatcgccagc ttgatattta acagctaagg ccacattata atgcgccaga
     9241 tagttcgtat atgcattatt gtcgatatat tctgtgtatt catctggacc aatgactctg
     9301 tgtatctcta aatgatcatc gacttttaca gctctgctca gccaaaaagc tgctgtttca
     9361 tgaatgagcg tttttccctt tgtttctaaa aacgattgat cctctgttgc ttggacatac
     9421 tcttgaacgg cataagcaag gtctgcactg atatgatgtt ctgcggcagc tgaagcaact
     9481 tcttgtcttg ttccggtttt gatattcaat gcagcaaatt tgggtgtctc ttcctgacca
     9541 gtgtgtgcgc tttcccatgg gaaaagtgca ccttgatagt gataatctct tgctttttgc
     9601 cgtgcgcctt ctaatcgatc ataacggtac agcagcaaat tctttgctac ttcaggaaac
     9661 tgatataaaa agaaaggcag gataaaaatt tccgtatccc agaaaacatg ccctttataa
     9721 ccttcgccag ttagtccctt cgcccctaca ctaacacttg gatcattgcg gggagtcata
     9781 atctgtaaat ggtaagcagc gaagtccatc gctaactgat cgaaagaaga atcgccttgg
     9841 atcgttatcc gatgctgatg ccaaaaatct gtccaataag acatcgactg ctctaaaatt
     9901 tctgtataac taacgctttt ctgggcttgg gcaatacttt tcttaaacgg gtctgtttgc
     9961 tgaagagagg tagagagcac gatgatcttc tccagcgtaa aggacgtatt ttttctgatc
    10021 ttttctgaaa aggaagcggt gatccggcga ttttttgctt ggaatacacc tgctttattg
    10081 aatttagctg caatcccaat atcaatttta ctttctgttg tctggtagga tgcactgatc
    10141 aaatcgtcac caaatactcg cagttctttt tcaaccaact gctgtgtacc aaaattggtt
    10201 tgctgtccat cgatacccgt tttcacatct acttggcagt cttcggtcaa cggcttgatg
    10261 accactttca gggctgcctg atggagatta ttttgatcag caacacgaca agtaatgact
    10321 tccacttttt ttccttgagc agtttcaatg agcgcatagc gtttaagctc tcccatttct
    10381 aaatctagtg cccgctcgta tgcaagaact ttcatcgtct caagagaaaa atgttcaccg
    10441 tcgattttta tttcccatct gatgacatct gggagattca ctaactcggc tgattctgct
    10501 cctaaaggtc ggttatatac accagctgca aacattcccc ttacttgatt ccgatagtct
    10561 tcctcctggc ttcctctgat accaaaaaat ccatttccaa tggtcatctg actcgcatac
    10621 ttattgatat actctaaatc aaactgtttt tcttctactt tcataaggta ataacttctc
    10681 ctgtttctgc cgaacgatat aaattttcca ccagattctg gatgacatat ccttgccagc
    10741 catctgcaat catctgagtc tggtcaccga gcgcccgatt cacaaaatga gccatactta
    10801 gttcatgtgg gtcattaact ggcgtggtct tttgtaagga aaccagcttt ccatctacat
    10861 cttcgaatag ttcgcctgga tacagattag cacctgcctg atcgccacaa aaagccacat
    10921 tcagtttgtc ttctctgata ttcaaagcaa acgaagtatt cagttggatg atcttgccgt
    10981 tttctaattc cagtgtgcca aaaattgcat cttctactgt gaatttgctt ggatcccatt
    11041 tcccgaattt ccctgaattt tttttcgtac caattttttg gaagctgtac gcccgaacgc
    11101 tttttacttt aggaaatcca gtaatataca tcgctgtatc aagcatgtga atgccataat
    11161 cgatcaaagg cccgcctcct tgaagttctt tgtcgataaa cgttccccag cctggaacac
    11221 cagaccgacg aagcgcattc gcttctacgt aataaatatc cccgagaaca tcaagatgat
    11281 tcttgatcat tgttgcttcg tcagaaaaac gatgctggaa tccataagcc aaaatctgcc
    11341 cgtttttatc ggctgtctct gccatctttc ttgcttgatc agctgtcata gctggtggtt
    11401 tctcgcacat cactgaagca ttagcttcga gggcagccaa tacatgttcg aagtgaaagc
    11461 gattggctgt acagacactc acgatatcgg gagaaatctc attcagcatt tgtgtaactg
    11521 atgtatacgc atgagaaaat cctgtacgtc ggcaaaagtc ttctgctcgc tggctgactg
    11581 gatcaaccac agcggccaat tctaagacat ctgatctttt ttgataataa gcagcatgta
    11641 ctttttctgc tacttgtcca gcgcctatga ttgctacttt cttcatttat ttctctctcc
    11701 tttgcttatt tacttattgt tattctttct ctattctttc tctaaatcat ttaaatgacg
    11761 cgctgtttcc agacagtttt tcaagtattg caatgattcc tgataaattt tcacttcatt
    11821 ttctcctcgc aaacgacatt catataccat ataaccttca tactcatttt gaagtagcgt
    11881 ttgaaaatgg cgagtaaaat caattgcgcc agatcctggt tggtagcgat gattatctgc
    11941 taaatggata tgacccacat actctttttg cgtagtcaat gcttttgaaa tatcatcttc
    12001 ttcaatattc atatgataaa aatcagcgat gatctgcaca tgtttcaatt gattagagtc
    12061 aatgtaatga cgcgcatccg ctaacaaatt gatcatatgg tcttggtatc ggttcaaagg
    12121 ctccaaataa ataaccgtac ctgtttcttc ggctacttta tctaaataac gaagtgattc
    12181 gctgactgct ttatagtctc cttctttgct tcggggtgaa accatcggcg gtaatcgata
    12241 agtgaacatt ccccaagctg ctgggataac gattcctttg cctccaacct cgcttagtgc
    12301 acgcaaaatc tcagcaattt gacgtacacc attaagacgc cgttcttcga taaagtcacc
    12361 gatccaccca tcgtagccgt tacaagctgt cactactggg atccctgttt ctttgattgc
    12421 ctgtttgact gtgtcgatat tttctattaa caacttaccg tcgatttcgt attcttcaaa
    12481 tccacagtct ttgataaatc taaatttttc taaaatgtct cttgggaaaa atgcttgatc
    12541 ttgcgtaccg aatttcattg ttctcctcct cggacttgaa cgcccatttt gatactttct
    12601 tctgggtgct ggtctacata acgcatgtaa gcttctgcgc tttctgcaaa tggcacaact
    12661 ggatcaatga tttcttcaca atccaagtaa ccgttcatca ataattccca acatgtgtcc
    12721 tcgattcgtt tacggttcca tcttgggtaa tctgggtttg gttcactaga tgctcgagca
    12781 aagacgattt ttgcattatt gaaatgtgct tcgcgaccaa gattaaaccc agctggaaaa
    12841 ggtttagcaa aggcaacata agaaatgatc ccgccatagc cgatccctct taaagaagct
    12901 tgtaatgcgg cagcactgcc actcgtttca ataactgaat ctactccacg tttatctgtc
    12961 aattccttta gacgaaaacc gacatctgct ttcataggat ctagcgtgta atcggcaccg
    13021 tatttttctg ctaattctct acgctgcgct atgggatcga tcccaacgat ggtagtagca
    13081 cctgcttttt tagctaattg aatcgcaatt tgcccgatag cgcctaaacc gaagattgct
    13141 acagcatcac ctgctcgaac atgtgcttcc cggataccac ctaaagcgaa ttgagcagga
    13201 tcgtaacata ctgcattttt ccattgatcc aaccgatcaa gtttacgtag tttataatta
    13261 tcaacaccgt ttgtaatcag cgtttcacga atgggtccat aagtgcagac taactctcct
    13321 ttttgatact ctgtcaccaa actgcccgtt tcttcgatcg taccgacaat catatttcct
    13381 aattgaaatt cgccaaatac cacaccgcgt tggcttcctt cttctcttgg caagaatagg
    13441 cgccattctt ctgaaaattc ttcatcgata aatggactta atcctctaaa gtcgacaatt
    13501 tctgttcctg gttttggagt agcgaaaatt actcggatac gtacttcgtt cttttcgatc
    13561 tcacggtctt cgtaatcttt gaatccggct attcttggtt ctaatgcaac taattttttc
    13621 atcttttctt tcctctttct tttcttttta tccttttacg ccgccttcga ctaaatcacc
    13681 tttaataaat cgttcagata acgcatacat aatgatgact ggtaaagcgg tcaccaatga
    13741 agcggccatc attcgtcccc aaatgtagtc tggtgtactg aataatgtgt tcaaaccgat
    13801 tggtaaagta aatttttcgg aggtcgacag gaaaatcgaa gcaaataaat aatcattcca
    13861 cgaaaccata aagcaataaa cgaagacaga aatgattcca gaaatagcca atggtataat
    13921 gatccgaata atgatctgga tccggctaag accatcgatc attgctgctt cttcaatatc
    13981 agtcggaatc gtgtcaaaat aactttttag catgaatatc gcagtaggaa gtgtttgaac
    14041 gaccatcgtg ataatcagtg ctgtattggt atcatacaaa cctagaccgg aaatgatttt
    14101 aaataatgga acaacgatca aaataccgga aaacatataa acggtgtaaa agctagcatt
    14161 gattttcgag cgagctttga agcgtagttt tgacaaagcg tatgccccgc tgatcccaat
    14221 cactactgca gttacggagg ctatcaagga gatcactaaa ctatttttga aatacatgat
    14281 gaatggaaaa atctcagcat tgaaaatatc ctgataatgt tcaaaagtcc attctttcgg
    14341 aaaaatagtt tgtgtcgttg caattgcttc ttgtgaatcc ttgaatgatg tcatcagcat
    14401 gatcaaaaat ggaaacaaat tgacagctaa tagcaacaaa atcgtcgcgt aaaataagat
    14461 tttcctgctc tttttatttt tcatttcaag tccaccttct ttcgtgagag caagacgacc
    14521 gctgcaataa tgatgaacaa tagaatcgat atagctgctg cttttccaag atcattgaac
    14581 gcaaaggctg tctgatacaa ataaacgcct aagatattga ctttattcgt cagtagatag
    14641 acatctgtaa acatatagaa catccagata gatcgtaaaa caatcacagt tgctagtact
    14701 ggtttgattg ccggcagtgt cacgatcttg aacttctgcc aagcatttgc accgtccatt
    14761 tcagctgctt cataaagcgt tttgtcgact gtttgcaaaa tagccaaaaa tgaaataaac
    14821 gcatacggat agtatctcca gatagcaaac aaaacgacca taaagaagct agcaactggc
    14881 tggtcgaacc acagcggtgc ttcgttgaaa agctgcaacc tatctactaa cagatcattg
    14941 acgattccat aactattatt gaacatatat ttccaagcaa aaatcaaaga aatagatggc
    15001 gtaacataac ttaataaaat cagtgaacgc accgttttcc taaatctgaa cttgcggtta
    15061 agcaaaatag ctacggctaa tcctaaagct gtactgcctg ctacaactaa gaatgtgtaa
    15121 gcaactgtta aacctaaaga acgataaaat tcactatcac ttaaaatttc aagataattg
    15181 cttaatccga taaaaacggc gtctgagtta ggattcagcg gcatatcgaa aaaactgatc
    15241 tgaatattgg aaagcattgg aatcagcact aaaacagcta ataaaagcat gcttggtgct
    15301 aaaagtccca tggctaattt taagtcagaa tgtttccttg gacgattcat tgaaacctcc
    15361 ccctgataat ctgccaatag ctatctactt ttttcgaaca ccattggcag aacttcttgt
    15421 tatttcgtat ttttttgtgc gtcagctaaa gcttgatcga catcttcgtt tccgacagtt
    15481 acttggttca ctgcttttcc gatcacacct gagcttgtga tatctcccat tttcgtgaaa
    15541 ttcttttccc cgactagtcc aaagacttgt acttcatcaa aagcactagc aatctcagat
    15601 ggcagctcgc caaaagactt gatgacttca ttttctttgt aaccatccag ttcgactact
    15661 tgtttattca ctggttgagc accaccagga gacatcaaga cccacttttc catgtttttc
    15721 ggttgagata agaaagctgt gaatgcttca gcagcctctt tttgtttctc gtctagacca
    15781 gaagaaatcg tcaatccaga tactgtgcca tagacagctt gatctttttg tgttgggata
    15841 gcaaaaccga tattttctga gttccccgct tcataaacag aaggcaaaat gtaagttgaa
    15901 tagattgcca ttggtgctgt tccattcatg aaagcatctt tgatttctgt cacatcatta
    15961 gagcctggca tcgtgtattg ggataagttt tgataaaacg acaatgcttc tctcatcttt
    16021 tccgtatcga tcgttacctc gccttcatca tccaaaacat ttgctccatt tgacaaagca
    16081 aattgagaga acgcttgctc actcattgtt ccttcagcag taggcatagc aattccatat
    16141 tgtttattct ctttatctgt gaaatgttga gcaattttta aaatatcatc ccaattttct
    16201 ggttctgaaa aaccagcttc tgataatttt tctttgtcat accaaatacc ttgaacccag
    16261 ccgctaattg gtgcagcaat atagcttttt ccatcttctg aacgaacaag gtttttggct
    16321 ccgtcataat aattatcttc tccagcttcc tcgataacgt tttggactgc cgtctaatca
    16381 atcagttcat ctttatccat cactttagca aaatcctgac tgacttccat tacttctggt
    16441 aatttaccgg aacgagctaa cgtaacgatt tttgtattga acgctgattc ttctaccggc
    16501 acttgcttga ttttgatgtc tggattttct ttttcaaaat cagcaaccag ttcattgatc
    16561 acacttaatc gttcctgttc gacagaagag tgcatgaatt gaatcgttgt ctgttgtgat
    16621 tcgttagagc tttgactttc accacaagca gtaagaagaa atccagtagc tagcagacag
    16681 gtagtaacaa taattttttt catttttttc cacctcttat tttattattt tcagccacat
    16741 atattcatac ggctggaata tcaactttcg ttcttgactg caatggataa tttgtccaga
    16801 aaacaggtct aggtaatctc cttttggtaa aagataacct gctgattgat tggaaaaatt
    16861 atggataact aagactttct cttccttcgc ttcgcgaata aaactgataa aagaatctgc
    16921 tgagtccagt aagtaaatca aactattcgg atggaaggct ttttcttttt ttcgaataga
    16981 tagcatctgg gtcaattcac catatactgc tgttcttaat ggatctgtct gcaactcttt
    17041 ctcaatatct gctaacaaaa atttttgccg attgattttt cgattctctc ctgttttttc
    17101 tacgcctttg taatcatttc gacttcccag cacactttga atataaattg ccggcacgcc
    17161 tggtaacgtt accaaaaatg aatgagcagc taaaaagcgt ttgcttctcc attccgtcgt
    17221 atctgttgga gaacttaacg catctagata cgtagcgttt atctcatatg gactggtcgt
    17281 tccatctggg tttttcttgt agtttactcg ggcaccctct ttcttcagct gttccactaa
    17341 ttcaaggatc gttttttccg gcagaatacc tcgtaccgga ttcaatccga taccgtcatg
    17401 ggaggctaaa aaattaaaaa aagttgtttt tttcgatgcg aaatcgatgg tttttaacca
    17461 ttctttcaac ttacttgtat tacccgaacg aatcgcttga agggtcaaag gtggtagcga
    17521 aaactgatag accatctgtg cttcattctc gccattccca aaataactga tattatcttt
    17581 gtgtggcaca tttgtctcag tgatcaatac cgttcctgga gctgcttcat cagcgattgc
    17641 acggaataat tggatgattt tatgcgtttc tggcaggtgt atacaagaag ttcctagttc
    17701 tttccataaa aatcccacag cgtccaagcg aataaatgaa gcgccttttt ctaagtaaaa
    17761 caaaagaata tcgatcattt tcaataaaac ttctggattt ttaaaattca agtctacttg
    17821 atcttcgcta aaagtcgtcc atacgtgttt ttctttcccg tttttgtcaa tgaacgttgt
    17881 aagtaacggg ctggtccttg gtctagtcac gctgcttgta tctgtatcca gtggcaaatc
    17941 aataaaaaaa tctttgtacg tatcattcaa gtttaaatat tcctgaaacc aagtactttc
    18001 ggcagacata tgattgcaga caaagtcgaa cattaaccgt gtttcgcttc tcatttcttc
    18061 tatatcttcc catgtgccca aacggtcgtt gattgcctga taatttacaa cggagaaacc
    18121 atcatcagat gtatatggga aaaatggcaa gaaatgtaca actctaaatg tatctgccaa
    18181 atacttttga taaaatttct taaatgtacg caaagttggt tgctgctctt caaaaaattg
    18241 atccccataa gtaatcaaga aaatatcttc ttcgtcccaa tgcagtttgc ctgcctggcc
    18301 tttcttctgc tgataaacac tgactttttg ttcaatcata gaggcggttt tctcagacaa
    18361 atctgagtcg cgataaatcg cttgtaaaag ttttgtatac atcggattcc cctttctttt
    18421 ttgggagcgt tcccaacgat ttgatcatat tatggaaaac gcttactgtc aatagcattt
    18481 ttttaaataa ttttgatata cacaaaaata caaataagaa agcttatgta tcaataatta
    18541 atagcttctt aaaaaaatat ggtctctcat gatcatgcaa gctattccta aattttcaaa
    18601 atcatagaca aaaaagaatg tctattgtac tatggaatta ttctaaaacg ctcccaaaaa
    18661 ggaggtgcat ataaaattga aacctactat ttatgacatt gcgaaaaaag ctaatgtctc
    18721 aaaatcaact gtctccagag tattaaataa ccagccaaat atctctgata aagcaaaagc
    18781 aagtgtactt caagcaatca aagaattgaa ttatgaaccg agcaaaattg caagaggact
    18841 gtcaggaaat ggttttgacg cgattctagc attatctcat cgtacttctc atacgaccta
    18901 tggcaatcct tttttttcag atgttattca atccatttct gccgtttctg aacaaaataa
    18961 cttcgacttg attctacaaa cggcaaaaac accagaagaa gagctagaaa aatgcgcgaa
    19021 aaagatccaa gaaaaaatga tccgaggaat tattatttta agctctacga tggatgaaac
    19081 acttcttttt gaattggatc aatacaatat tcctattgtg gtaatcggaa aagtcggaaa
    19141 cgactacacg aacatctact cagtggacac ggataatttc caggatagtt acgatttggt
    19201 ggaaacactg atcaagaatg gacaccgtca tatcggctgt ctccatgctc cgacagaagt
    19261 ttatgtatcc aatgatcgtc tcaatggtta ccgtcaatgc ttatttgatc accacctaga
    19321 tatccgtaat gaatggatta tagacggcgg ctttcgctta gaagatagca tggcagcaat
    19381 gaatgattta atgaagctac gagaaagacc aactgcgatt ttttctaccg atgcattaaa
    19441 atcattgagt atttacaaag tggcagaaca atctggaaag cagatacctg atgatctttc
    19501 gatcgcagga ttcagtgatc ccttattgtc ctccctattt tcgccacagt tgactcggat
    19561 agacattccg acaaatcagt taggaatcaa agccacagaa cttttattcc aactaatcca
    19621 ccaccaatac cctgaagaaa aaagaatcat tctttcaacc gagattactc tcacagattc
    19681 gatccaacaa caagaaatgt agaacagaat tataaaagaa cagaaacact gaggataagt
    19741 cagttactct gttctttttt caatcactca tccctcgtta ccccctcccg gtattttagc
    19801 gaatttttct tattttccat ctgttttaga tagctgtgga taactataat gtttgtgtta
    19861 aactattttt tccacaggga agaaaaaact atttttaacc acgttgtgta taagttttta
    19921 tagttcgttt ttttaaacac atttaccctt atttcaatcc atgttatttg gggatactta
    19981 tctctaaaac ataaatagaa taacagacat gtctactggt tttgttttat tcgaggaatt
    20041 attcaataat agctagcaaa atattaaaaa taaccgctct atcttcccat caatttattt
    20101 tgcattcaaa aaatgatcta tctttacttt tgttgattga cttctcttgg aagatgatcg
    20161 ttccgatacc ttaattggat acgaaccgat gttgttaaga tcctttccca cttttcttct
    20221 agttagacaa attattttag acaaaccaaa aaagaggttg tgacaataat ttgtcacaac
    20281 ctctttttta aaatatctat tttgtttgat tgttcattgc gtcttctgca gccatttgcg
    20341 cttcaatatc tgaaatactg tagacatttt cgcttgctac accgacttct tttggttcca
    20401 tgtcacgata acgttgcata ccagtaccag ctgggatgat cttacctata ataacatttt
    20461 ctttcaaacc aagaagagga tctttcttac cgcggatcgc agcatccgtc aagacacgag
    20521 ttgtttcttg gaatgatgca gcagataaga aactatttgt ttctaatgat gcttttgtga
    20581 tacctagtaa gacaggtcga gaagttgcag gaacgcctcc tgagactagc gtattgtagt
    20641 tttgatcttt aaagtctgcg atgtctaata atgtacctgg taagatatct gtatcacctg
    20701 gatccattac acgaacttta cgcagcattt gacgaaccat tacttcgata tgcttgtcgc
    20761 cgatttctac cccttgcata cggtaaacac gttgtacttc acgaagcaag tagttttcaa
    20821 cagataatac atcgcgaact tgcaacaatt gttttggatc gattgatcct tctgtcaatg
    20881 gtgcaccacg gtggatcata tcgccttctg ctactttcat acgtgctgta taaggaacag
    20941 tatacgtacg tgtatctgtt tttcctttga ttgttacttc tttggtacgt gttgcaggat
    21001 cttctgagat atcgatgaca tcccctgtta cttctgtgat cactgcttgc cctttcggat
    21061 tacgtgcttc aaagatttct tggacacgag gaagaccttg agtgatatcg tctccggcaa
    21121 ccccacctgt atggaatgta cgcatcgtca actgagtacc aggttcaccg attgattgag
    21181 cggcgatcgt accaactgct tctccgactt caacgtcaga gccagttgca aggttgcgtc
    21241 cgtaacaatg tttgcagaca ccatgttttg tattacatgt gaagacagaa cggattgtca
    21301 ctgtttcgac acctgcatca acgatttgtt ttgcgatgtc ttcggaaatc aattggtttc
    21361 ctgcaatgat caattcattt gtttcaggat gacgtacttc tttacgggtg taacgtccca
    21421 ctaaacgatc ttctaatgat tcgatgattt catttccctc gcggatggct tggatttcaa
    21481 gacctcggtc agtaccgcaa tcttcttcac ggatgattac atcttgggcc acgtcaacca
    21541 gacgacgagt caagtaacct gaatcggcag tcttcaaggc tgtatcggtc atccctttac
    21601 gagccccgtg agttgagata aacatttcca agacggatag tccttcacgg aagttcgaaa
    21661 tgattggcaa ttccatgatt cgaccattag gagcggccat caaaccacgc attccggcaa
    21721 gctgtgtaaa gttggaaatg ttaccacgag ctccagaatc agacatcatg aagattggat
    21781 ttttcgcttc caaaccttcc atcagttttt gttggatgct gtcttttgca gcattccaaa
    21841 cagcaatgac acgttcataa cgttcgtcat ctgtgatcag accacgacgg aattgttttg
    21901 taatagtttc aacttgttta tgggcatttt caatgatttc ttgtttttca ttcagtacac
    21961 tgatgtcagc gatccctact gtgataccgg catgtgtcga atgtttgtac cctaagtctt
    22021 tcatacggtc aagcatctta gaagtttctt ttactttgaa tcgtttgaag acttctgcga
    22081 tgatgtttcc taagtttttc ttcttgaacg gtaatactaa ttcttgctct ttgatatgtg
    22141 caggaatatc agtaccagct tcaacaaagt atttgtccgg tgtttggacg gtcaagttga
    22201 agtctgttgg ttcattcaga taagggaatt caggaggcat gatctcgttg aagatgatct
    22261 taccaactgt tgtgatcatc gtacgttctt tttgccattc agtaaatggt ttttcaccta
    22321 atgagttagg gttcacaccg atacgtgaat gtaaatgaac atatccgttg cgccatgcga
    22381 taacggcttc gttttgatct ctgaagacca ttccttcgcc ttcgcgtcct tcttcttcca
    22441 ttgtcaagta gtagttacct agaaccatat cttgagaagg agtaacaact ggtttaccat
    22501 ctttagggtt caagatgttt tgagcagcta acatcaacat acgtgcttct gcttgtgctt
    22561 cttcattcaa tggaacgtgg acagccattt ggtctccatc gaaatcggca ttataagctt
    22621 cacatacaag tggatgcaaa cggattgcgc gtccttgtac taaaactggt tcgaatgctt
    22681 ggataccaag tcggtgaagc gtaggtgccc ggttcagcaa tactgggtgt tccttgatta
    22741 cgtcttctaa aacatcccat acttcgtctt cttgacgttc gattttacgt ttcgcatttt
    22801 tgatgtttga agctagttcg cgttgaacaa gctcacgcat cacgaatggt ttgaataatt
    22861 caatggccat ttcttttgga agtccacatt ggtacatctt caagaaaggt ccaacaacga
    22921 taacggaacg acctgagtag tcgacacgtt tacctagcaa gttttgacgg aaacgacctt
    22981 gtttcccttt caacatatga gaaagagatt tcaatgggcg gttacctggt ccagtaactg
    23041 gacgtccgcg acgaccgtta tcgatcaatg catctactgc ttcttgcagc atacgttttt
    23101 cattttgaac gatgattcca ggtgcattca agtctaacaa acgtttcaaa cggttattac
    23161 ggttgattac acgacggtaa agatcattca agtcacttgt tgcaaaacgt ccaccttcta
    23221 attgaaccat tgggcgtaaa tctggtggaa taacagggat aacgtccata accatccagc
    23281 ttggttgatt tcctgaagcg cggaatgctt ctaaaatatc caaacggcgg attgcacgtg
    23341 tacgtttttg tccttgtgca gatttcaatt cttctttcaa ttcggctgct tctgcatcta
    23401 gatcaacatt atcaagtaat tgtttaatcg cttctgcacc catagcagct tggaattctt
    23461 gtccatattg ttcacgtttt tcgcgatatt cgcgttctgt caacaattgt tttttctcta
    23521 aattcgtatt tcctggttcg atgactacat atgaagcaaa ataaatgatt tcttccaaag
    23581 cgcgtgggct catgtctaat acaagaccca tacgtgaagg aatcccttta aagtaccaga
    23641 tatgtgaaac aggagctgct aattcaatat gtcccatgcg ttcacggcga actttcgaac
    23701 gagtaacttc cactccgcat cgatcacaaa cgattccttt ataacggata cgtttgtatt
    23761 ttccgcaggc acattcccag tcttttgtag gaccaaaaat ccgctcacag aacaaccctt
    23821 cgcgttcagg ttttaaggta cgatagttaa tcgtctcagg tttttttact tcaccgtaag
    23881 accagcttct gattttttcg ggagaagcca aacctatttg catactttcg aatttattta
    23941 catcgatcaa aaggggttcc ctccatttca tttaatggca aaccgcaaga cggctgatct
    24001 tcgaccgcct tgcagctcat agaccggatt agtctaaatt atcttctgcg gtttcaaagt
    24061 tttggatgac atcgtctttt tcatcttcca cttgttcagc agctttcttt tctaattctt
    24121 tggcagtttg ctgttcggca aattttgtca aagcatcaac agtgatcaaa tcgtcgtctt
    24181 catcgtccat gtcgcgaagt tcgatctctg tttcttcgat atccaagaca cgcatgtcca
    24241 gacctagtga ttgcaattct ttcaccaata cgcggaatga ttccggtaca cctggttttg
    24301 gaattggttc acccttgacg attgcttcgt atgttttcac acgtccgact acgtcatctg
    24361 atttgtatgt caagatttct tgtaaagtat aagccgcacc gtaagcttcc agtgcccata
    24421 cttccatttc accaaaacgt tgtccaccaa attgagcttt acctcccaat ggttgttgtg
    24481 taaccaatga gtaaggtccg attgaacgtg catgcaattt gtcatcgacc atgtgagcaa
    24541 gtttgatcat gtacatcaca ccgacagaca cacgtccatc aaatggttca cctgtacgtc
    24601 cgtcgtacag aacagttttc gcatcgctgg ccataccggc ttcacgaact gtttcccata
    24661 cgtcttcatc acttgcacca tcaaatactg gcgttgctac gtggatacct aactgacgtg
    24721 cagccatacc caagtgtaat tccaatactt gcccgatgtt catacgtgaa ggcaccccta
    24781 aaggattcag catgatatcg attggtgttc catcaggtag gaatggcata tcttcttccg
    24841 gcataatacg ggatacaacc cctttatttc cgtgacgacc ggccatttta tccccttcat
    24901 ggattttacg tttttgaacg atataaacac gaactaacat gtttacgcct ggtgacaatt
    24961 catctccagc ttcacgagta aagattttca catcgtgaac gataccgccg ccgccatgtg
    25021 gtacacgtaa tgatgtatcg cggacttcac gagctttttc gccaaagatc gcatgcaata
    25081 gacgttcttc tgcagataat tctgttaccc cttttggcgt gactttccct acaagcaaat
    25141 cgccatcttg gacttctgca ccaatacgga tgatacccat ttcgtctaaa tcttttaatg
    25201 cgtcttcccc gacattaggg atttcgcgtg tgatttcttc aggtcctaat tttgtatcgc
    25261 gggcttctga ttcatattct tcaatatgga tagaagtgta tacgtcatct tttaccaaac
    25321 gacggctcat gatgatcgca tcttcatagt tgtacccttc ccaagtcatg aaaccaacta
    25381 aaacgttttg gcctagagcc atttcgcctt gttccataga tggtccgtct gccagagtat
    25441 cccctttttc gactttctca cccaaatgaa cgattggacg ttggttgtag cttgttccgg
    25501 agtttgaacg acggaatttt gttacatcgt atttatctaa tgcaccgttg tcgcggcgta
    25561 cgcggatttc agaagcatca acgtattcaa cgacaccatc atgtttacat aacaaagcag
    25621 ctcctgagtc atgcgctgat ttgtattcca taccagtacc aacccatggt gcttgaggat
    25681 tgatcaacgg cactgcttga cgctgcatgt tggcacccat caaggcacgg ttggagtcat
    25741 cgttttccaa gaaaggaata catgctgtcg caacggcaac tacttgttta ggtgatacgt
    25801 ccatgtagtc tactttatca atagatactt ctaagttttc actttgagca cgagccataa
    25861 caacgtcttg agcaaatgtt ccatcttcat tcaatgggct gtttgcttgg gctacgatgt
    25921 aatggtcttc gatatcagct gtcaagtagt cgatttggtc agtaacacga cctgtttcac
    25981 ggtctacacg acgataaggt gtttcgataa atccgaattt atttactttc gcataactgg
    26041 acaaactatt gatcaacccg atgtttgggc cttcaggagt ttcgatcgga cacatacggc
    26101 catagtggga gtagtgaacg tcacgaactt cataaccggc gcggtcacga gtcaatccgc
    26161 caggtcctaa ggcgaaaaga cgacgtttgt gtgtcaattc gccaagaggg tttgtttgat
    26221 ccatgaactg tgacaactga gaagaaccaa agaattcttt gatacttgcc acaactggac
    26281 ggatattgat caattgttga ggtgtcaatg tttcagtatc ttggatcgac attctttcac
    26341 gaaccacacg ttccatacgt gctagcccga tacggaattg gttttgtaaa agttcaccga
    26401 ctgaacggat acgacgattt cctaagtggt cgatatcatc gacattgccg ataccttcca
    26461 tcaagttcaa gaaatagctc attgaagcaa tgatgtcggc tggacgaacc gtttttacag
    26521 ctgcttctgg atagccgttt ccgatcacgt ttacttcacg ttcagggtct cttggtgaaa
    26581 atactttgat gacttggaca gtcattggat ctgtgaccac accgtcttct gatggatagt
    26641 aagtcactga atttaggcca ttatcaatga aaggagctag tgtttccatg acttggtgag
    26701 tcagaactgt tcctttttca acgatgatct cgcctgtttc tggatcaact aatgtttcag
    26761 ctaatgtcag attcaataga cgtgttttca aatctaattt tttgtttact ttgtaacgac
    26821 caacgtttgc taagtcgtaa cgttttggat cgaagaaacg agcattcagc aagttacgtg
    26881 agctgtctgc tgtttttggt tcgcctggac gcaaacgttc gtaaacgtct ttcaaacctt
    26941 cttctgttct tgagtcgctt gcgtttttat gcaagtcttt ttcgactgta ttgcgtaatg
    27001 tttcgctgtc gccgaagatt tcaaagatcg tatcatcgga accaaatcct aacgcacgaa
    27061 ctaatacggt taaaggaatc ttacgtgtac ggtcgatacg tacataagag atgtcttttg
    27121 catcagtttc catttctagc caagctccac ggttagggat aacagtagaa ccgaatcctt
    27181 cttttccgtt tttgtcgact tttccatgga aatagacacc tggtgaacgg actaactgag
    27241 aaacgattac tcgctctgcc ccgttgatga tgaatgttcc ttgttctgtc attaatggga
    27301 aatcaccgaa gaatacttct tgtgctttga tttcgccagt ctcgcggttt gtcaaacgca
    27361 atgttacatg taatggtgca gagtagtttg catcatgcgc acgagcttct gctactgtat
    27421 actttggttc tttcaattca taatctacaa attccaaaga tagattgcca ttgaagtcat
    27481 cgattggcaa aatgtcttca aacatttctc taagtccctc atctaagaac cattggtaag
    27541 agtctgtttg aatttcgatc aaatttggta attccaacac ttcactgatt cttgcgaaac
    27601 ttctacgttc gcgatgtttt ccgtatttta ctacgtgtcc agccaagctc ttcacccctc
    27661 taaaatgtca ttcaaaaaga ctacccgatc aattgttaca ataatatttc aaatattatt
    27721 tttaggtaac aacagacatt ttttgcggct tttaggcaaa aaaaaaccaa aaatagaaca
    27781 ttctcttgaa accttacttc gtgagcttct acttttgttt ccttatatta aagccgaaac
    27841 ggacaatatt tcgtttctgc cttttcttca tcagatagtt tttgcaactt catatactac
    27901 acttattttc tataaaagtc aacacttcct ggcgtttctt ctgctttttc gcaacatttt
    27961 cttaatgttt tcaattttat gttttcaatt atctgacaat tcttaattga cagacctttt
    28021 tatctcggtt atactttaga aaattcattt tgtggaggaa cttctatgcg aaccaacatc
    28081 aaccaaatcg caccaacaca actgaataac ttttacttta gctactttag ataggtttgt
    28141 attcatcatg atggatacaa acgttaaacg acagtttgta tctatgatgg ctaaagaact
    28201 ttgtattgca gcaaaaagcc acgtagacaa aatgctaagt ggctgagcag tgaaaataca
    28261 aagtaaaagt atcaagcatt ctactttttc aatttatttt ccgacttttc aatccatttg
    28321 gacattttgt ctgaatggat tttttgtttc ccaaaattaa ggaggaaaaa gaaatgaaaa
    28381 aaaatataat catcggatta ggcgctgccc tgctactagc tttaggaggt tgcgcacaaa
    28441 aagacaattc cgcagaggca tcagatggac aaaaaacaat tggcgtattg caacttgtac
    28501 aacataactc gttagatgct gcctataaag gattcaaaga aggattagca gaagaagggt
    28561 ataaagaagg cgataatcta acaatcgatt atcaaaatgc ccaaaacaat caagacaacc
    28621 tgaaaagtat gagtgagaaa ctcgtcaaag aagatcctga tttgctactt ggaatcgcca
    28681 ctccagcagc acaatcttta ttaaatgaaa caaccactat cccgatgact gtcacagcgg
    28741 tcacagactt ggaacaagcc catttagtca catccaatga aaaacctggc ggcaatgtga
    28801 ctggcacgac agatatggtg ccaatcgaaa aacaaatcgg cttactgtta aatatcgtgc
    28861 cagacgccaa aacaatcggc atcatgtata acaacggtga agcaaactct aagatccaag
    28921 ctgatttggc agaaaaagaa ttgaaaaaag cgggcgtcaa agtcaaagta ctgacagcaa
    28981 attccacaaa tgatgtccaa caagtgacga aaagtctagc taaagatgta gatggaatct
    29041 atattcctac tgataacacg ttcgcaagtg cggcaagtgt tgtcggtgaa gtcgcaaaag
    29101 aaacaaaaac acctgtcgtt gctggcgcag ttgatcaagt caaagacggc ggtctagcaa
    29161 cagtaggaat cgactacgaa agcttgggca aacaaacagg gatcatggca gcaaaaatct
    29221 tagacggcaa gaatccaagt gaacttcctg tcgaaacagc gaatgatttg gaactgtatg
    29281 tcaataaaga catggccaaa gcattaggca tcaatccaga cagcatcaaa gaagctgaat
    29341 aaaacacagg aggattctca tgacaaattt gctctctctt ttcttatcat ctgcatcgca
    29401 aggggtctta tgggccctac ttgcgattgg tgtatacgtc actttccgta tcttggacat
    29461 tgccgacttg actgctgaag gaagctttcc tttaggtgca gggatcgcgg cagtaagtat
    29521 tacaaatggc tatcatccat tgacagcttg tcttctaggc tttttaggga gtgcggcagc
    29581 agggcttgtt tccggactgc ttcacacaaa attgaaaatt cccgcccttc ttgcagggat
    29641 catcaccatg actggtttat attctgtcac atcccgtgtg atgggtgcgc cgaacatctc
    29701 tttattgggt cagccaacga tctttcattg ggtcgagtca ttcggcataa caaaagacaa
    29761 cgctgtactg atcgtcggtc tgctttttgc tttgatcgtt gtatgtttac ttgttttgtt
    29821 cttacgtaca gaaacaggac ttgctattcg tgcaactggc gataatctgg caatgagcga
    29881 agcaaacggg atcaacacag ataatatgaa gatcatcggt tatatgattt ctaatggatg
    29941 cattgctctt tctggctcct tgcttgcgca aaacaacggc tttgctgatt taaattctgg
    30001 tattggaacg atcgtaattg gacttgcttc tattatcatc gcagaagttt tgttacgtaa
    30061 ccagccacta tttctccgtc tcttgactgt cgttttaggt gcggtcattt atcgttttat
    30121 tttagcgtta gtcttcgaac tgaatgttga accaagtgat tcgaaacttg cttctgcttt
    30181 cgtgctagtg atctgtcttt ctttcccgca gatccagcaa aaattccatt tacctcaaaa
    30241 aaagaaaggc ggtagtgtca aatgaatgac gtcttaacat tggaaaatct ccatcatacc
    30301 tttgaaaaag gaacgatcaa cgaaaatcat gtcctgaaag gcattaatct ttccttagat
    30361 cccggcgact tcgtgacgat catcggtgga aatggggctg gtaaatctac tttgctgaac
    30421 agcatcgccg gtacattttc tgtcgatcag ggtcaaattt tattgaatgg aaaaaatatc
    30481 acgaaaaaat ctgttgtcga acgttcgaaa tccatcagtc gcgtattcca agatcctaaa
    30541 ctagggacag ccgttcgttt aacggtagaa gaaaatcttg ctcttgctat gaaacgagga
    30601 aaaaaacgcg gcttcttccg tggtgtcaaa ccacaagacc gaacattttt caaagaccag
    30661 ctggttcggc taaatttggg gttggaaaat cgtttatcct cagaaatcgg tttgctgtct
    30721 ggaggacaac gtcaagctat tacgttattg atggccacat tacagcgtcc agaactgatc
    30781 ttattagatg aacacactgc agcgcttgac cctgctactt ccaaaacggt gatggaattg
    30841 acagaaaagc tgatcactga gcagaatctc actgctttta tggtcactca tgacatggaa
    30901 gacgcgatcc gctatgggag tcgactgatc atgctgcatc aaggaaggat cgtcgtagat
    30961 atccagcaag aggaaaaaca gcagctcaca gtgccccaat tattagcgtt gttcaaacaa
    31021 aacagcggca cggcattaaa agacgatcaa gtacttttat cttcataatc agaaagagga
    31081 tgggacaaaa aatgaacgcc caccctcttc ttttttctct ttccttcttt cgtttttgct
    31141 ttatgtatca accgttgttt cttcgaaaac tattttgttc tctccttctt cctgatagaa
    31201 tggatgggaa aggagcttga tgccatgaca acgaaagaca aggtacttca attattgaaa
    31261 aagacaccag attttctttc cggagaaaag ttggcacagc aactggaagt ttcccggaca
    31321 agtatttgga aagccatcaa agaattggaa aaggcaggct atcgttttga gcacgggcct
    31381 acagggtatc gttacctgcc ctctgacgta ctagatgcaa aagaaatcca gcaagagcta
    31441 cggtcgttta ttcctgattt gaaagtacaa acgatgatga cttctgaatc tacgatgaaa
    31501 gatgccaaac tggcagcagc tcaaggagat tctgtttcga agttatttgt tgctgataca
    31561 caagaacaag ctcgtggacg ttttggacgg ccttttttcg ctgaacctgg acgaggaatc
    31621 tacatgagtc tcttgctcca tccagacaaa cggtttgatg aattgcctca atatacgatc
    31681 atcgcagcca gtgcctgtgt gaaagccatt gaatctgtaa ccggtcgttc tgcttcgatc
    31741 aaatgggtca atgatatcta catggatgga aaaaaagtct gtgggatttt atctgaagca
    31801 gtcagtgata tggaaagcgg caggatcagt catatcatca ttgggatcgg gcttaatttt
    31861 tctgttcctc aaaatcattt tccagctgat ctccaagaaa aagccatctc tgtctttccc
    31921 gacggacaag ctagtgtcac aaggaatcag ctaatcagca aaatctggca agaattgttc
    31981 acttatcttt ctcacccaga aaaagcgttg gacttctata aagaaaaatc attcgtattg
    32041 ggaaaaaccg tgtcgttcaa tcaaaaagga acgacttatg tcggtcttgc aaaagaaatc
    32101 ggtgatcatg gcgaactgat cgtccaaaca aatgaacaga agatgagttt gtcttctggc
    32161 gaaatcagtc tcacatctat ccgtacgcaa taattatcag atttcacaaa aggacacctg
    32221 atctcataca gtgtcctttt ttctgaattc tcttcaaaag actctcctta ttctatcagc
    32281 tgacagtttc tctatcctct agaaaaaggt attctaaaaa tatctataaa gcatggtaca
    32341 ctttctttaa atgaatcaat gcaaaaaaca agagagtcat cagtttacac gatcaaaaga
    32401 gatagcaggc cgcttccttt ttcaatctta tagatagacc atgggtaacg ataaaaacaa
    32461 aaaagaactt gcgacttatt ttgccgtaag ttctttttta gctagtgcct taatctctta
    32521 atcccaacaa acgtctcgca tagatcacct gaccagagtg catagcagca tcatcaataa
    32581 tagaaacgag acgcattcct cgtgtgactg gtggtgtcca gttctcgtca attacttcat
    32641 ctagctcgga aggttccagc cttcttaagt aagaaatagc aaaatcagca gctcctcgca
    32701 agtatcctag cagatcttct atttgattag cttggatctg ctttgcttgt tccagactat
    32761 gcttccaatc ttgttcgtta tctgctatcg tcatcggaaa ccggctttcc cagtcttgac
    32821 tatgccaaat tggagaagtt cctgctaaat cagcaatctg gaaatctaat tctcgagcgg
    32881 tatgccaagc cagccaagtc attgatttga tctgcggggc tctatcttcc actggaaaac
    32941 gattggcctc ctcaatagag acgccttcaa acaaacgttc aaaccgatcg tatgcccgat
    33001 ccacactctc gcatagcata tctaaataat ccatttattt tcctcctttt tatttatcct
    33061 acttactttt tcctaattct aggataccta cttatatgtt actacacacc cttatttttt
    33121 acactttaac agtcaccatc atcaatagtt tggagattga aagaaaaaga tagtgtcgaa
    33181 ctatcaattg aacaagaagc aacaatatga acgtttcatt aatattcttt aaataaacaa
    33241 tgatttttca aacgaacagt ttaagactag gagaaaaaga gtataatagg aaaatgtttg
    33301 aaaggaaagg aaggggaaaa atgaaaaaaa gggcaagttt actagtccta gttgctttgt
    33361 tgttcaatat cttttcgtat ggtgtggccg tttcagcgga aacatacatt cctaaagacc
    33421 ctgggaatat ttataatgat ctaactggta actatggctt gttaggaatt gctagtcaat
    33481 tccacgtatt tgctaaaaat aagacaactg tgaatgcaca tacagacgga aatatagcaa
    33541 cacatgaact tgatgcaaaa aataattttg gtacagagct tcatgaaggt ttattgaacc
    33601 aagaaataaa ttatatacaa aaaactgatt ctttcgctaa ttcttcaggc atacctacag
    33661 gtagcacaag aatgaataaa tttgtcgttg gcagtaacgt ggatgtagca cttcaagatg
    33721 gtcatcctac agtcaatgga tccaggcttg atcacttaac tccagatgat ttttataaag
    33781 atcgtgctgg gcatgaatat attgatttcg agcaggaatt tgctaaattg aatgtagcag
    33841 caaatgatct tgcaacgatc actccagcta aaacatatac tgctgcagat tttccagaca
    33901 tgaacaatcg gacaatcgat ttaactgatt tatcagatac cgggttttta ttggtaaata
    33961 tcgatgcaga agtgttaacg atgaatacgc cacttcaaat cattaatcca aatgatcaag
    34021 tagttgtatt taatgtcatc aacagttctt ctgcattgaa cgtacagtca ccaatcaaat
    34081 acaatgatcg ttcaaatcat gaaacagaag atttttcgga tgcgaatatc tcttggaatt
    34141 ttggaaatga gatgactgat ttgacaatca gtgctccttt tcaaggaaca atccttgcgc
    34201 ctaatgctac tatccgcatt actcaaaacc aagacggaac gattatagga acaaatgtga
    34261 ttttagatgc agctaccaat cgttgggatc ctaacgaaat atttatcagc gacaatggta
    34321 cagatacgac agacacaagc gacagtacag atacatctac cacaagtgat agctcagatt
    34381 catca
//
LOCUS       DACBYO010000024        34118 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.024, whole genome shotgun sequence.
ACCESSION   DACBYO010000024 DACBYO010000000
VERSION     DACBYO010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.024"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(99..1229)
                     /locus_tag="IVD26_001101"
     CDS             complement(99..1229)
                     /locus_tag="IVD26_001101"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAP6079090.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1878..3080)
                     /locus_tag="IVD26_001102"
     CDS             complement(1878..3080)
                     /locus_tag="IVD26_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6079091.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="IVD26_001103"
     CDS             complement(3140..3343)
                     /locus_tag="IVD26_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP6079092.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="IVD26_001104"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="IVD26_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4880..5692
                     /locus_tag="IVD26_001105"
     CDS             4880..5692
                     /locus_tag="IVD26_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6079093.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6913)
                     /locus_tag="IVD26_001106"
     CDS             complement(6716..6913)
                     /locus_tag="IVD26_001106"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079094.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="IVD26_001107"
     CDS             complement(7059..7937)
                     /locus_tag="IVD26_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6079095.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="IVD26_001108"
     CDS             complement(7976..9094)
                     /locus_tag="IVD26_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAP6079096.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="IVD26_001109"
     CDS             complement(9091..11190)
                     /locus_tag="IVD26_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAP6079097.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="IVD26_001110"
     CDS             complement(11241..12062)
                     /locus_tag="IVD26_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP6079098.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="IVD26_001111"
     CDS             complement(12059..12868)
                     /locus_tag="IVD26_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6079099.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="IVD26_001112"
     CDS             complement(12889..13383)
                     /locus_tag="IVD26_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6079100.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="IVD26_001113"
     CDS             complement(13395..13883)
                     /locus_tag="IVD26_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6079101.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="IVD26_001114"
     CDS             complement(13960..16656)
                     /locus_tag="IVD26_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6079102.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="IVD26_001115"
     CDS             complement(17084..18157)
                     /locus_tag="IVD26_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6079103.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="IVD26_001116"
     CDS             complement(18154..18981)
                     /locus_tag="IVD26_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079104.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="IVD26_001117"
     CDS             complement(18982..19788)
                     /locus_tag="IVD26_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079105.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="IVD26_001118"
     CDS             complement(19800..20885)
                     /locus_tag="IVD26_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079106.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="IVD26_001119"
     CDS             complement(20902..21444)
                     /locus_tag="IVD26_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6079107.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="IVD26_001120"
     CDS             21702..22691
                     /locus_tag="IVD26_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAP6079108.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="IVD26_001121"
     CDS             22688..23425
                     /locus_tag="IVD26_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAP6079109.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="IVD26_001122"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="IVD26_001122"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAP6079110.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="IVD26_001123"
     CDS             23989..24621
                     /locus_tag="IVD26_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP6079111.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="IVD26_001124"
     CDS             24706..25353
                     /locus_tag="IVD26_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6079112.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="IVD26_001125"
     CDS             25358..26341
                     /locus_tag="IVD26_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAP6079113.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26744..28258)
                     /locus_tag="IVD26_001126"
     CDS             complement(26744..28258)
                     /locus_tag="IVD26_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAP6079114.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="IVD26_001127"
     CDS             28396..29202
                     /locus_tag="IVD26_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079115.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="IVD26_001128"
     CDS             complement(29377..29946)
                     /locus_tag="IVD26_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6079116.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="IVD26_001129"
     CDS             complement(30029..32089)
                     /locus_tag="IVD26_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079117.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..33844)
                     /locus_tag="IVD26_001130"
     CDS             complement(32366..33844)
                     /locus_tag="IVD26_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP6079118.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT        10255 a         7082 c         5747 g        11034 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttaccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctctttta
//
LOCUS       DACBYO010000025        33263 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.025, whole genome shotgun sequence.
ACCESSION   DACBYO010000025 DACBYO010000000
VERSION     DACBYO010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.025"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(41..229)
                     /locus_tag="IVD26_001131"
     CDS             complement(41..229)
                     /locus_tag="IVD26_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAP6079119.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="IVD26_001132"
     CDS             499..861
                     /locus_tag="IVD26_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP6079120.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="IVD26_001133"
     CDS             913..2595
                     /locus_tag="IVD26_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAP6079121.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="IVD26_001134"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="IVD26_001134"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAP6079122.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="IVD26_001135"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="IVD26_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAP6079123.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="IVD26_001136"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="IVD26_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP6079124.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6430..7434
                     /locus_tag="IVD26_001137"
     CDS             6430..7434
                     /locus_tag="IVD26_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079125.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7435..8379
                     /locus_tag="IVD26_001138"
     CDS             7435..8379
                     /locus_tag="IVD26_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079126.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8379..9341
                     /locus_tag="IVD26_001139"
     CDS             8379..9341
                     /locus_tag="IVD26_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079127.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9368..10282
                     /locus_tag="IVD26_001140"
     CDS             9368..10282
                     /locus_tag="IVD26_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079128.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10308..12089
                     /locus_tag="IVD26_001141"
     CDS             10308..12089
                     /locus_tag="IVD26_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6079129.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12437..13123
                     /locus_tag="IVD26_001142"
     CDS             12437..13123
                     /locus_tag="IVD26_001142"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP6079130.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13143..16724
                     /gene="smc"
                     /locus_tag="IVD26_001143"
     CDS             13143..16724
                     /gene="smc"
                     /locus_tag="IVD26_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAP6079131.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16733..17542
                     /locus_tag="IVD26_001144"
     CDS             16733..17542
                     /locus_tag="IVD26_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6079132.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17553..18551
                     /gene="ftsY"
                     /locus_tag="IVD26_001145"
     CDS             17553..18551
                     /gene="ftsY"
                     /locus_tag="IVD26_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAP6079133.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18738..21005
                     /gene="gshAB"
                     /locus_tag="IVD26_001146"
     CDS             18738..21005
                     /gene="gshAB"
                     /locus_tag="IVD26_001146"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAP6079134.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21094..21546)
                     /locus_tag="IVD26_001147"
     CDS             complement(21094..21546)
                     /locus_tag="IVD26_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAP6079135.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21696..22646
                     /locus_tag="IVD26_001148"
     CDS             21696..22646
                     /locus_tag="IVD26_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAP6079136.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22639..23598
                     /locus_tag="IVD26_001149"
     CDS             22639..23598
                     /locus_tag="IVD26_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAP6079137.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23595..24350
                     /locus_tag="IVD26_001150"
     CDS             23595..24350
                     /locus_tag="IVD26_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6079138.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24373..25326
                     /locus_tag="IVD26_001151"
     CDS             24373..25326
                     /locus_tag="IVD26_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6079139.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25970..26266)
                     /locus_tag="IVD26_001152"
     CDS             complement(25970..26266)
                     /locus_tag="IVD26_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAP6079140.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26621..26977
                     /locus_tag="IVD26_001153"
     CDS             26621..26977
                     /locus_tag="IVD26_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP6079141.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26987..27886
                     /locus_tag="IVD26_001154"
     CDS             26987..27886
                     /locus_tag="IVD26_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAP6079142.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28403..29134
                     /locus_tag="IVD26_001155"
     CDS             28403..29134
                     /locus_tag="IVD26_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP6079143.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29279..31306
                     /locus_tag="IVD26_001156"
     CDS             29279..31306
                     /locus_tag="IVD26_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAP6079144.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31414..32511
                     /locus_tag="IVD26_001157"
     CDS             31414..32511
                     /locus_tag="IVD26_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP6079145.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32818..>33263
                     /locus_tag="IVD26_001158"
     CDS             32818..>33263
                     /locus_tag="IVD26_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP6079146.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11138 a         5762 c         7123 g         9240 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag taaagcgatt
     6301 ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg ttataaaacg
     6361 ctttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga agcagagagg
     6421 ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac aggattccga
     6481 ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga caaaaacgag
     6541 attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac tacgattatg
     6601 ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa cgatctgaat
     6661 ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat cggaatgatt
     6721 ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca gatcaaagaa
     6781 ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc actagaattg
     6841 ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc ccatgaacta
     6901 tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa acctccaatc
     6961 gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca gattcttgat
     7021 ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac tcatgactta
     7081 ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca gttcgttgaa
     7141 gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg ctctttactg
     7201 aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga aggtgtcgtt
     7261 ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat tccatggata
     7321 ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa ccacttggta
     7381 cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt gtagatgaca
     7441 gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg attcttcaat
     7501 cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga aaaaggaaag
     7561 acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa agccgttgtg
     7621 ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt aacgaagcga
     7681 agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca agattcaatg
     7741 tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat ccgaaatttt
     7801 gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga tatcgttggg
     7861 atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca acgtcaacgt
     7921 ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga tgaacctgta
     7981 tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg aatccagcaa
     8041 gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa acacatgtgc
     8101 gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag agaagacatt
     8161 tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc gcaaatcgat
     8221 gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga gtatatccaa
     8281 aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac gatcacaact
     8341 acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg attctgcgac
     8401 gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc ttattagccc
     8461 aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat ccggcagtga
     8521 tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag tacttccgtt
     8581 ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa cgctctgttg
     8641 ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg acagttgtcc
     8701 ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa aattcaatct
     8761 tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta tttatcttcg
     8821 gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca agtggatcac
     8881 aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg aaatatattc
     8941 tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa tatctgcgaa
     9001 gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc aaaggggtac
     9061 cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg atggcttctc
     9121 aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa aagatttttg
     9181 gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac tataccgtga
     9241 tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta ctttcagata
     9301 tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca gaaaggagaa
     9361 tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc ctatggggat
     9421 acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat taggtttgct
     9481 agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag acaaagtgat
     9541 gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac aaggacaaaa
     9601 gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga tcataggtgc
     9661 tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca tcggggttgg
     9721 attagggatc atctctggct actacggagg gatcattgac aacatcttga tgcggatcgt
     9781 tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat cgattatttc
     9841 cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg tagctaaagc
     9901 ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca gtgcctcaaa
     9961 aacaatggga accaatgatt ttaaaatcat gttccgcgaa atcatgccga atctaagttc
    10021 attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg agacaacttt
    10081 gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat tgatcggtta
    10141 tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg catcaatcct
    10201 tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc gttctgcaga
    10261 tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg aagaaaacga
    10321 tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg ggcggaggta
    10381 cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa ttaacttttc
    10441 caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa gctgcggtcg
    10501 caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat tcatatgatg
    10561 cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat ttcagaatca
    10621 cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg acaatcaaag
    10681 taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat gtgattttcc
    10741 cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac actttccgta
    10801 acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc ggaatcaaaa
    10861 aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc atgcttcaat
    10921 cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt gtagcaatca
    10981 aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc ccttattaca
    11041 tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac tactggaatg
    11101 gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt gcaactgaag
    11161 cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact tacgatacct
    11221 ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat acttatctag
    11281 gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat ccagattcaa
    11341 aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat aatgcagtag
    11401 gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct ccagtattcc
    11461 agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa gcgaaaaaac
    11521 tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa gacaaagatg
    11581 gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg caaccattgg
    11641 cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac acaacaggtc
    11701 gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct gaaattgatg
    11761 tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta tggggaccaa
    11821 atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg atcaacgata
    11881 tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa aaatggcaac
    11941 aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa gtattgccag
    12001 tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca tgggcaaatg
    12061 tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa gggcgatgtc
    12121 ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc aaggcgctga
    12181 tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt aagtcaaatt
    12241 tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg aaactaaacg
    12301 aatttttcac aacttctcgt caatcactag gattattaaa gctttactta ccttttgacc
    12361 gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa aaatatccat
    12421 aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa actataacat
    12481 cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct atgtgaatga
    12541 gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag atgccgtttt
    12601 agaactgatg gtttctcagt atttattccg tttatatcct catttgccag aaggaaaatt
    12661 gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg ccaaagaatg
    12721 tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag gacgtacgcg
    12781 accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc ttgaccaggg
    12841 attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca aagcaggtgc
    12901 tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa aatcaggtga
    12961 tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac gagtattttg
    13021 gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat cgaaaaaatt
    13081 agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag tgagggaaag
    13141 ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac aagacagtca
    13201 ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga aaaagcaata
    13261 ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg cgaggcggaa
    13321 aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat attgcagaag
    13381 tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat gagatcagtg
    13441 taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa caaagctgca
    13501 gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa tcgttctcaa
    13561 tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac cgtcgtggga
    13621 tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa gcagaacaga
    13681 agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac gaattggaag
    13741 aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta cggctaaaag
    13801 aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca gcaaaaaaag
    13861 attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc aaactatctg
    13921 agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat gcgcaagccg
    13981 atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa ctgaagcaga
    14041 cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa agctcgcaag
    14101 aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa aagcttcaag
    14161 aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct gaagcaaatc
    14221 tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa ttattggcag
    14281 aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga aacgaactga
    14341 agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg ttagccaagc
    14401 aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa ttgacacaaa
    14461 agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa atgatccaac
    14521 aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg tatcaattaa
    14581 tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc caagaaaact
    14641 attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag ctttcgggta
    14701 ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta gctatcgaag
    14761 cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat gctcggcaag
    14821 ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca ctgacgacaa
    14881 tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta gaagggttta
    14941 tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg gttcaaaacc
    15001 tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc gcgcaaacga
    15061 tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc ggaggatcca
    15121 tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa aatcaagaat
    15181 tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca caagaaaaaa
    15241 aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa gttttgcgta
    15301 cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta caaaacatca
    15361 taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag acacgtgaac
    15421 tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac aaacaaacag
    15481 atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt caagaaagcg
    15541 accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa caagcagatc
    15601 ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt gcccgagtcc
    15661 aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg acattgacag
    15721 cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt aacgaattat
    15781 ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag cgagatagaa
    15841 ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt gagcaaaaag
    15901 cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa atgattttag
    15961 ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa gcttcccaag
    16021 actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc ttaaaagaac
    16081 agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa caagtcagtg
    16141 aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa aaccaattgt
    16201 ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa gtatttgaag
    16261 ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt aaagctgaat
    16321 tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa gtacaacctc
    16381 ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca cttacagcca
    16441 tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc ttagatgagg
    16501 tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg agcgatttcc
    16561 aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc gcagcagatg
    16621 tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct gtacggatgg
    16681 aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga aaatgatcaa
    16741 attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga tttcagatga
    16801 gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc tatgtacagg
    16861 acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag atgaaggtga
    16921 ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg aaatcatgga
    16981 aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc agcaattgga
    17041 tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg ccccaaggaa
    17101 gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg atataagcga
    17161 tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag aagaattaga
    17221 tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca tcaaaacaag
    17281 aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta tttctttatt
    17341 ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg aggaaaatga
    17401 tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg tgcctttcgt
    17461 caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag ccaaagtgat
    17521 ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa atcaagcgtg
    17581 cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac gacaagggtt
    17641 tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc aattttcgaa
    17701 cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca gatgtaggtt
    17761 ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc agaaatgcga
    17821 aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc tatgaagcgg
    17881 aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca gttattttgt
    17941 ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc catcagttca
    18001 aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct ggagcaatcg
    18061 accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc aatgcaggag
    18121 gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag caggcagatg
    18181 ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg aacgaattag
    18241 aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa acacttcttg
    18301 tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc aaagaaacaa
    18361 cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc ggtatcgtac
    18421 ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt gaaggaatcg
    18481 atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa ggattactaa
    18541 aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag ctccttgttt
    18601 gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac ttatttgtaa
    18661 gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt agattcatat
    18721 gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc aatgcgcgcc
    18781 cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt gatcttgcag
    18841 gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat cacccctata
    18901 tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc gattctattc
    18961 ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct ataccgaaag
    19021 aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac gaagagatca
    19081 ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta gcaaaaaaat
    19141 acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt ggcgatgagt
    19201 tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa ttcaaaacag
    19261 aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc acttatttat
    19321 tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat ccgcaagaac
    19381 ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat gtgaaagttt
    19441 cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa gaagggaaac
    19501 tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag aaagtcgcag
    19561 atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg aatccttatg
    19621 caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg atgtacatgt
    19681 tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg actcgaaata
    19741 acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa ggtagagaaa
    19801 ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct ctttatttag
    19861 tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg aaactctatc
    19921 aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat caatattata
    19981 aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa ctttctactc
    20041 agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta gatgagtcgg
    20101 atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat gcaaacatga
    20161 caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta acgaaaaaag
    20221 tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc atggaagaag
    20281 cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct aaatcaacca
    20341 attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat tatcaagcag
    20401 gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt atgccgggaa
    20461 cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg cgagtccctg
    20521 ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa aaaaatagtg
    20581 accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta ggtgaattag
    20641 aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa gccaatcaaa
    20701 ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc gatatgactg
    20761 atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca ctaggagcta
    20821 agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca actgataaaa
    20881 aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat gtttatcctt
    20941 ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat cctgaagtat
    21001 tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat caaaagcttt
    21061 ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc agaagctttt
    21121 tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt attttttttc
    21181 gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc cgaattcctc
    21241 aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt tcgttgctag
    21301 ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta tggaagcatc
    21361 tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga tcatttcagc
    21421 aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat gctgttcttc
    21481 agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta catcatcttg
    21541 tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag catattccca
    21601 ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac ttaaaataag
    21661 aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga ctagtagcat
    21721 tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta caattgtcag
    21781 aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt ttgccacgaa
    21841 cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc atgcaacatt
    21901 tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt gcgcgtttag
    21961 gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga tccttgacag
    22021 cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga ttgttcctcc
    22081 agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc attggttcag
    22141 ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca tggcttcaag
    22201 ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt gttccattgt
    22261 tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc gaatcgtttg
    22321 cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc ttagtatcat
    22381 tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga gtgatcattc
    22441 cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc gtaactgctt
    22501 tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg atttttcctt
    22561 atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc ctttatcttc
    22621 tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg tatgcttgtt
    22681 cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa ctggcatttt
    22741 gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct agctgtcagc
    22801 agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc ttcagtattg
    22861 ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat cggaggagtg
    22921 acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct gatggtcggg
    22981 ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct ttttttatta
    23041 ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt tttacaagtc
    23101 atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag ctttggcaat
    23161 atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg gtacctgtta
    23221 tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc agtaaacctc
    23281 gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct tttgacaggg
    23341 acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc aaatatcagt
    23401 tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt tctggtagct
    23461 atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg gaatacaaca
    23521 gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt gattcgcgaa
    23581 aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat ggaaaatcag
    23641 tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt atcggtccaa
    23701 atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca aaagatacag
    23761 gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa ttagccaaaa
    23821 aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg aaagaattag
    23881 tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac gaggaaatcg
    23941 ttcaggaatc actggaacac cttgggttag aagaaatagc ggatcaatcg attgacactc
    24001 tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa gacacggatt
    24061 atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt caaatcatgc
    24121 agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt cttcatgata
    24181 tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga cagttattta
    24241 cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta tacgaaatgg
    24301 acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa aactaacatt
    24361 aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc atttggttta
    24421 gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag cagcacacaa
    24481 actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt gccaaataat
    24541 ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc tcttggtgtt
    24601 ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc atcctataaa
    24661 aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa tcagcttcag
    24721 ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct aagtcaaatt
    24781 gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt ccagcaaaat
    24841 gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca attagaggaa
    24901 ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa aaaagcacta
    24961 gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag attcggtttc
    25021 atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc cactcacggt
    25081 caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt tgtagtagac
    25141 agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa tgaactggta
    25201 gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga tgtctggtat
    25261 ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa tcaagcattt
    25321 aaatagcata aataacagag gattaaactc tcatactatg taacaataat gtttcttaca
    25381 ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg taaaatcgta
    25441 ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac gtgaattcat
    25501 tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt gtgatccatt
    25561 ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg aaacttagat
    25621 aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg atgttccatc
    25681 tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat tttctgtcca
    25741 gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac gatgttccat
    25801 ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta ttttctgtcc
    25861 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa caatgttcaa
    25921 tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt taggcatgtg
    25981 tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg gcgggaagct
    26041 tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt ttatactcgc
    26101 ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa atatccaatg
    26161 ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa ccctcgatat
    26221 tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg attcctccaa
    26281 agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc cgtgaacaaa
    26341 aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta ttttttgtta
    26401 tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt tttccgttca
    26461 agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa tcataataaa
    26521 cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt agttgcatct
    26581 gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag aagtgacaaa
    26641 agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt tattagatat
    26701 cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg atacggcatt
    26761 tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt ctgtagtggc
    26821 tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca tggatgatcc
    26881 atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac caagcggctt
    26941 gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg gaaaattggc
    27001 gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc tgatgcagct
    27061 ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag atacggctaa
    27121 taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat tatctacgac
    27181 atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga tggaccattt
    27241 tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga ccgttctttt
    27301 agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg aggcaatcgt
    27361 acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa cagatctcga
    27421 ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa
    27481 acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc
    27541 tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat cattcggaga
    27601 attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc atcgtcgctt
    27661 tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt attattatga
    27721 atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct atgatcctat
    27781 gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc aaacacaaca
    27841 tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca gcattagtaa
    27901 tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag atccatttat
    27961 cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg atcggatgat
    28021 ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga taatcacaaa
    28081 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
    28141 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
    28201 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
    28261 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
    28321 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
    28381 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
    28441 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
    28501 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
    28561 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
    28621 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
    28681 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
    28741 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
    28801 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
    28861 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
    28921 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
    28981 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
    29041 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
    29101 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
    29161 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
    29221 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
    29281 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
    29341 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
    29401 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
    29461 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
    29521 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
    29581 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
    29641 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
    29701 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
    29761 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
    29821 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
    29881 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
    29941 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
    30001 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
    30061 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
    30121 gcaaagaagt cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga
    30181 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
    30241 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
    30301 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
    30361 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
    30421 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
    30481 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
    30541 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
    30601 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
    30661 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
    30721 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
    30781 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
    30841 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
    30901 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
    30961 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
    31021 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
    31081 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
    31141 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
    31201 tacagctcat cgtggaatca gaataaatat tcctgtagaa aaccaaagaa tcggaacctt
    31261 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
    31321 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
    31381 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
    31441 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
    31501 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
    31561 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
    31621 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
    31681 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
    31741 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
    31801 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
    31861 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
    31921 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
    31981 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
    32041 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
    32101 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
    32161 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
    32221 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
    32281 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
    32341 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
    32401 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
    32461 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
    32521 aacaaatagt aaatttttat tattgtagga tggttgggct ctttttataa caatataaaa
    32581 tataccattt tattaataaa aatgcatact agtaaatgat ataattctaa taacaggttt
    32641 gatcgcgaga aaggccaaat aaaacgctct ccaaaatgtt aaaaaaaaga caggacgatg
    32701 tatattatac aaacaagaat cgctgacaac agtgactcgg atccaggaaa tcagttttat
    32761 ccccagctag ttggtgaatg catggaaagt aatatacgta gaaagagctg atgactaatg
    32821 aattatgagt tttttttaag caaagaagat cacagaagtt attcattact taaatattta
    32881 gaagcaagct caaatttatc agagtcaata tcgaatgttc aagaagagtt gtcgctatcg
    32941 acatttctct tgaaaaaaac gatcgataag ctgaaacatg atttacaaaa gttcgatcta
    33001 gagaaaaatt tgcgagtaac cgtcagtgaa ttggatatat gtctggaaat taatggaaaa
    33061 tgttctagca aagctctgtt atctcgttat ataacggatt ctttatctat gaaaatggta
    33121 ttggctttct ttcaggaaaa atatatctca gtagaaaatt ttgctaaaca gcatcacgtg
    33181 agttattctg tggcttataa agtattacaa agactaaaaa gaaatctaaa aaaatatcaa
    33241 attttttttg aaaagagaaa gtt
//
LOCUS       DACBYO010000026        32015 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.026, whole genome shotgun sequence.
ACCESSION   DACBYO010000026 DACBYO010000000
VERSION     DACBYO010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32015
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.026"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..1368)
                     /locus_tag="IVD26_001159"
     CDS             complement(<1..1368)
                     /locus_tag="IVD26_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAP6079147.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTI"
     gene            complement(1355..2386)
                     /locus_tag="IVD26_001160"
     CDS             complement(1355..2386)
                     /locus_tag="IVD26_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079148.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            2417..2638
                     /locus_tag="IVD26_001161"
     CDS             2417..2638
                     /locus_tag="IVD26_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAP6079149.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(2803..3540)
                     /locus_tag="IVD26_001162"
     CDS             complement(2803..3540)
                     /locus_tag="IVD26_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAP6079150.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(3693..5033)
                     /locus_tag="IVD26_001163"
     CDS             complement(3693..5033)
                     /locus_tag="IVD26_001163"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAP6079151.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(5270..6793)
                     /locus_tag="IVD26_001164"
     CDS             complement(5270..6793)
                     /locus_tag="IVD26_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAP6079152.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(7171..7782)
                     /locus_tag="IVD26_001165"
     CDS             complement(7171..7782)
                     /locus_tag="IVD26_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP6079153.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(7905..8030)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(8112..8828)
                     /locus_tag="IVD26_001166"
     CDS             complement(8112..8828)
                     /locus_tag="IVD26_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAP6079154.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(8834..9403)
                     /gene="scpB"
                     /locus_tag="IVD26_001167"
     CDS             complement(8834..9403)
                     /gene="scpB"
                     /locus_tag="IVD26_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAP6079155.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(9387..10184)
                     /locus_tag="IVD26_001168"
     CDS             complement(9387..10184)
                     /locus_tag="IVD26_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAP6079156.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(10154..10525)
                     /locus_tag="IVD26_001169"
     CDS             complement(10154..10525)
                     /locus_tag="IVD26_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP6079157.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(10544..11431)
                     /gene="xerD"
                     /locus_tag="IVD26_001170"
     CDS             complement(10544..11431)
                     /gene="xerD"
                     /locus_tag="IVD26_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAP6079158.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(11527..12000)
                     /locus_tag="IVD26_001171"
     CDS             complement(11527..12000)
                     /locus_tag="IVD26_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP6079159.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(12105..12968)
                     /locus_tag="IVD26_001172"
     CDS             complement(12105..12968)
                     /locus_tag="IVD26_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP6079160.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(13164..15263)
                     /locus_tag="IVD26_001173"
     CDS             complement(13164..15263)
                     /locus_tag="IVD26_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAP6079161.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(15483..16592)
                     /gene="rpoD"
                     /locus_tag="IVD26_001174"
     CDS             complement(15483..16592)
                     /gene="rpoD"
                     /locus_tag="IVD26_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAP6079162.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(16616..18457)
                     /locus_tag="IVD26_001175"
     CDS             complement(16616..18457)
                     /locus_tag="IVD26_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAP6079163.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(18639..21032)
                     /locus_tag="IVD26_001176"
     CDS             complement(18639..21032)
                     /locus_tag="IVD26_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP6079164.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(21139..21999)
                     /locus_tag="IVD26_001177"
     CDS             complement(21139..21999)
                     /locus_tag="IVD26_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAP6079165.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(22058..22579)
                     /locus_tag="IVD26_001178"
     CDS             complement(22058..22579)
                     /locus_tag="IVD26_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAP6079166.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            22899..23618
                     /locus_tag="IVD26_001179"
     CDS             22899..23618
                     /locus_tag="IVD26_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6079167.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            23644..26235
                     /gene="mprF"
                     /locus_tag="IVD26_001180"
     CDS             23644..26235
                     /gene="mprF"
                     /locus_tag="IVD26_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAP6079168.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(26423..27610)
                     /gene="tuf"
                     /locus_tag="IVD26_001181"
     CDS             complement(26423..27610)
                     /gene="tuf"
                     /locus_tag="IVD26_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP6079169.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            27978..28334
                     /locus_tag="IVD26_001182"
     CDS             27978..28334
                     /locus_tag="IVD26_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP6079170.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(28575..29579)
                     /locus_tag="IVD26_001183"
     CDS             complement(28575..29579)
                     /locus_tag="IVD26_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAP6079171.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            29745..30596
                     /locus_tag="IVD26_001184"
     CDS             29745..30596
                     /locus_tag="IVD26_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAP6079172.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            30613..30858
                     /locus_tag="IVD26_001185"
     CDS             30613..30858
                     /locus_tag="IVD26_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079173.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            31045..31749
                     /locus_tag="IVD26_001186"
     CDS             31045..31749
                     /locus_tag="IVD26_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079174.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         9093 a         6685 c         5537 g        10700 t
ORIGIN      
        1 aatcgttccc caatgaagtt gttcagtctt agaaaaaagc ttcctctttg gcagaagttc
       61 tgcttttgct ccatcaatat cacaacaatt ctgcggcttt tcggagagtt tttcgccaaa
      121 ataagctaag atgaattttc tgcggcagtt ttcttcatta atatagcgaa gcatctgctg
      181 caggcggaat tctttttctt tttcctgacg tttgagccgt tccacccaat tttctggttt
      241 ttcagactgc tggatcagct ccatccattt tttttgcagc tcatcaaagg gagcttgctc
      301 tgtggcatat tccaaataaa gctcaaaact ttgtcgctgt tctctagaaa gttgattaaa
      361 gaaataatgg atacgttcat ccccactttg ataaaaaaga attgctgcac tttcttcctg
      421 atctctgcct gctcgaccga tttcttgtac atagttttct agactgtctg gcaaatcata
      481 atggaccaca taacggatat cagatttatc gatccccata ccaaatgcat tcgtagcaat
      541 gagaaactgc agctgatttt ttacaaactg ctgttgaagt tgtcttcttt gagctgcatc
      601 aagaccaccg tgatagtatc caactgtaaa acgttccctg aataaatgat acaatcgttc
      661 gacttctttt tttgttgcac aataaatgat tgccgctcct tgtgctcttt ccatgaagtg
      721 ttcaagttct tgttcttttt gctgcgtttt ccgaacaaaa agcgagatat tttgccgatt
      781 gactgattgt ctgatctctt ttggtggtcg atcaaatagt acatgacgta tatctcttgc
      841 tactaaatct gttgctgtcg ccgttagtgc cagtgtgacc gggtttccta aaagctttcg
      901 gatttttcct aactgttgat attctggacg gaaatcaact ccccattgag acacgcaatg
      961 agcctcatct actacatata acgcaatatt ttgttttttc agatgctcta aaagagaagg
     1021 attagtcaac atttcgggac tcaaaaacaa aaatttatat tgcgatagat gacggaggac
     1081 gtatcttctt tcagattgcg aaagtaaact attgaaagca gctactcgtt tctcccctcg
     1141 tttttgtaat tgcgtcactt gatcttccat tagagaaagc agcggtgaca cgatgatgac
     1201 cagaccttcc attaaatacc ccgtcaattg atagcaaagg ctttttcccg ttcctgtagg
     1261 caaaatagcg agagtatctt ctccatcaag caacgcctga ataatttctt cttggccggg
     1321 acgaaatgaa tcaaatccaa aatatttttt taattcattt attaacattc tgtatcgctt
     1381 cctttctcaa tagatagatt tgatacaaac gaaattctcc ataatctaat tgtccatcta
     1441 cattccattc gctaaagcgc cactctcgca cggaatcctt atttggttcc aaacgttcga
     1501 ttgtttctgc agagagaatc cactcgtatg gaaaatcatc aaaaaacaag gcccactcaa
     1561 taagatgatc tgttactgtt cctcttttta aatgacggat tgccatgatc tggtcaattg
     1621 tctgaccatt cataaacatc tgcttggtga tcatcatgct ttgattgaaa ttttgctgta
     1681 ataatgaatc gatcaaagcg tgccaaagcg aatctggccg tttttcgatt tgtgctaaca
     1741 aaaggtggat acatctgctt tgttgcagat aaaccgctga ctcatcattg ttttttgcca
     1801 gctgataagg aagcagccct gttcgctcat ttccagataa ttggttagct aaaaaatctg
     1861 ctgcttcttc tggtatctcc gaaaacagct gcaccaaact ctcatacgca gtatcaatca
     1921 aaatttcacg tggcaattgg ctttcactaa gccatttttt tagttggaaa gtataaaaag
     1981 gacttgtctc tgctggaaga tagtcttgaa tacccgttgc cagattagaa attacttgaa
     2041 cagcaaattt aatgagccgc caactagttt cccctgttct gccatagcgg tcaaaacgca
     2101 aaccagtatg ttctatttga tgttcggaca acatatcagc ccctgcaggc gttagctttg
     2161 cttcattttc atttatttcg atccaacctt gctgcgcaat tttttgcaaa atttgataaa
     2221 acttatcctg cttcaattct ggaaaactgt tatggataaa caaaagttcg tgggtaaatc
     2281 cataaataag tactgaagtc gttcgttttc ccacaaggag ttggtaaaga gaactaatcc
     2341 gcagcttgtg tcctgatgaa aatagcgata aaataaaaac aatcatatta ttctccttaa
     2401 gttaggatgg ttagaaatgt cactactatg taaacttgta cctgaacgct gtattgcatg
     2461 cggtctttgt caaatcgaag cgccagatat tttcgattat gatgaagaag gaatcgtttt
     2521 atttgcccaa gaaccagagg ctcatcaaca gttcgtgatg ccggaagaag aaacatatgt
     2581 aaaaaaagcg tatcaaaaat gtccagttcg agcgatttta ttagaaaata aaatataaat
     2641 ataaacgaaa ctttaaaaac gtacactaag ttctctaaac ttgaaaataa gccgggatct
     2701 gtttctcttg ttccgtgaaa tcccgactta ttttgaaaga ttcatttgct atctatagtt
     2761 aattgactag ttttttcacg gaccctatag gacccattta tattatttca actttttcag
     2821 ccagttttcc aatgtattga cgatcacagt ttgctggtct gcgttagaaa tttctgcctc
     2881 tccatctcct ttttgctcac catagctgcc aaaacctcca tgatttccgc cattgattga
     2941 tacatactct gttctttccg gtaaatactg cttagcttct tgataagctt cctgattcaa
     3001 tactttatct tttgtcgccg tgatcgataa aacaggaaca gctgattctg tcaatgttcc
     3061 ttttttgtcg ggataacttg ccatgaagaa tacccctttt aaatgtttgt ctgaatgatt
     3121 cttattgaca taacgacttg ccattacgcc acctaatgaa tggccaccga tcacataatc
     3181 ggaatttgga aaatcttctt tgaccttatc cgctttgttt ccgcccatca ctgctagatc
     3241 aagtggcatt ttgacaatag cgactgaaaa gccgtttttt gctaaatctt gcgcccaaat
     3301 actataactt tctggctcta cgagagcacc aggataaaaa ataagtaatg gagactttcc
     3361 atgattcttt ttctctcctt caaaaaataa gtaatcttct ttgttttttc cttcttttac
     3421 caacacttgc gcttctgacg atggttcgta cgtattttgc tgtatatagt aataaccggc
     3481 tccaccgagt aatcctaaaa tgatgactaa gccaattagt attcgtctaa atattttcac
     3541 tttctcccac cttttctatc tgagtgaccc ctttttctta atcaagtatg attatacctt
     3601 aaaaaaataa gagagaaatg caaactttcc agcatcaaat aaaaaaagac ggaatatcca
     3661 tttgaatatc cgcccttttt gtatgtttat ttttatttag cacataaacg atacacagct
     3721 tctgcataaa tttccattgc tttatacata ctacttaatt cccatcgttc attcgcctgg
     3781 tgcataaagt caggagtatc agggaacatc gcaccgaatg ccacacactg gttcatcgta
     3841 cgagcaaaag tagcgccgcc tgatacaaac ggttcagtca tgtctccagt aatatcgcga
     3901 tatgtcccca atagattttt cactaactca ctgtctagtg gcacgtataa tgaatcaagg
     3961 aagtcaaatt cttcataagt caacccatat ttttctgctg ttttagttaa tttagctact
     4021 aaatcatctt tcttgaatgt aacagggatt ctcatatcta caccgatttt tgtttgttct
     4081 ggtgtgattt ccaaacttgc aaagttcatc gttagctcgc cggattgttc atcttctgtt
     4141 ttgcccacga cagcttcacc agttgcattt tcttgaacta attttcctaa gaaattgatt
     4201 gggccaaaat caaatacttc tgaaagagca attgccagac gagaaatagc attcactcct
     4261 tgtgctgcat ctttcgcgtg gatactttta ccaagaacga cgatgccttc accttgttct
     4321 tcgaaatcga attcgtgttt tttcaatgct tcttttactt cagaaagctt ttctccagag
     4381 taaggagctg catcaggaac aacattcaac gctcctccag cttttacaga aaactcgttc
     4441 gttcctggtc ctgtcaagta agcttgcaat aagccttttt ctgcataaat taaaggaaat
     4501 tcagcatctg gcgcaaatcc ttgcgtaatt ccttcttctt tttcgttata tttttctaaa
     4561 caacgccata aattttcttc atctgtacca aagataaaac gaatacgtgt cttgaattcc
     4621 acgccagcat caatcaaagc tttgacggca tacattgccg caatagaagg acctttgtca
     4681 tcttgggatc cgcgaccaac taaccagccg tcttttatag ttggatcgaa tggttttgtt
     4741 tcccaattat tttcgtcccc tgctggaaca acgtccatat gacacaagat accgaataat
     4801 tcatctccag agccaatctc tgaataaccg taatagcctt ctggatcttt aaatgttcta
     4861 aatcctagct tttcactgat ttccaatact ttatccaaag cttcaatcac ttttttaccg
     4921 aagggatgtc cttgtcctga atctgcttca tctagtacgg aaggaattcg gatcaattcg
     4981 ctcaatgatt ctaatgcttg ttcatgatgt tgttctgtca caaatttttt catgatatta
     5041 tcctcctaat atgttaaaaa gggtcatgtc aaattcctcc gacacaacct cttcttctca
     5101 aataatgacg ttttaagcct gctccatcag caagcagaat gttcttaaca aatgatgaaa
     5161 gaaaaaacac tcactgaatg gagctattga cttatccacg tgcttatcga tagccgttta
     5221 tcggtttctt cattcttatg atagaccttg tacctgtatt tgtctaggtt tagaacattg
     5281 ctgctacacc taggatcaca cagatggcta caaataatat cgcaattaat ttaccggtaa
     5341 atttccacca cactgaaaca tcgaaacgag caattgctac agcacccatt acgatagcag
     5401 atgttggtgt aattaagttt actaaaccag atgcagattg ataagcagtg attactaaat
     5461 ccttaccgac gccggcaaat tcacccatag gtcccatgat tcccattgtt gcagcagcta
     5521 agccggaagt tgaaggaatc aagaatgaca tagggatata gaaaataaat gtaataatga
     5581 tgaatacact tgaagataat gaacttaatc cttgttcgcc ccaatgtaag atggtgtctg
     5641 tgattaatcc attgttcata accacttgga taccacgagc aacagctact acgattgcta
     5701 caccgatcaa atcagaagca ccagctaaaa attcagagac aaattcagac tctttcatgc
     5761 cataagtgat tgctactacg atggacatta ctaagaataa catagtaatt tctgggaagt
     5821 accagtcacc taatggaagc atgcttttac ctagaaccgt acctagtacc ggaaggtttg
     5881 ttaaccagtt tgtcaatgat tcaaaaatcg tgaaattcgc attcaaggtt gtccaaggaa
     5941 tcaaactgat gatcatgata ccaaaagtaa taaagaacaa tacattaaca tgtttttgtt
     6001 ttttcgtgat tacttcttga cgaccgattg cttcaatatc gaaatgcttc atatcttctt
     6061 tacgttggtt gtatactaat gattttgttg gatctttttc gatctttgat gcataacgat
     6121 acacatatac aatagaaata gctaacaaaa taacgaacat caagaatcga agaccaatac
     6181 cttcacccat cgaaatccca acagcttgtg aagctacgcc tgttgcaaaa ggatttaccg
     6241 ttgaagctag acagcctact tgagacccta ctaatacgat tgctacagct actactgtat
     6301 caaagcctac agccatcatg actgggatca gtaaagcata gaatggaatc gtttcttctg
     6361 ccattccgta agtagagccg cctaatgcaa ataacagcat caatactgga ataagcattt
     6421 tttcttttcc tttgaatttc ttcacaactg aagcaatccc ggcatctagt gcccctgttt
     6481 tgttgataat acctaaaaat ccaccaacaa ccaaaatgaa gaaagagatt gggattgcag
     6541 caggtgtttc tttagttagc tcccccgctg gtacacctag catcccattg attggcgcca
     6601 tgaaaatatc ccacagccct tgaggatttt gttgtactcg ttcatatgat ccagcgacga
     6661 tgttgcctgc atcgtctaca ctatagtgcc cagctggtat aaaccaagta agtacagcga
     6721 ttactgcaat aataataaat aagaccgtat acgctgaagg catttgaaat tttttctttt
     6781 ttgtttgttc catcttcttc ttcctttctt ttccgttaga gacaacaatt ttggctctaa
     6841 tgttatttta tcaaaaagag tatcagaaca aaaataataa cacgcatttt gtaaaacttt
     6901 tgttcaaaaa gttcgttttt ccctattccc tcctcttttt tcaggttttt aaagctttct
     6961 tctttttcat tgtagcgttt cctttttttt ataaacaaac attttcgtct tttaaaagga
     7021 gaagaatttc acatttgcaa agaattgatt gatttttatg cataaatcaa aaaaatactc
     7081 aaaacaaaca aataaaacgt ttacattatt gcatgtcttg tatttttttc caaaaaaaaa
     7141 gaccaagaaa tttcttgatc tttttgatat ttatttgact gctgtatgac gttgttcgaa
     7201 ctgatgttgt tttcgactta accatggaag aagttgcgca tgcagcacta aaaagacagc
     7261 actcacgatg aatcctttga tcaagttgaa aggaacgatc ccaatcagta catagtttgc
     7321 taaagacatg cccagcatct gtgttgcgtt cagccctaaa aacattaagt aaagaggcgt
     7381 aataacgaaa taatttgcga tactcataaa aatagttaga gcgatggttc ctgtaatgac
     7441 acctaaaaat ttgtttcttc ctttatgctg tttctttaca ctaaagaaat aataaatcgg
     7501 gaatgtaaag atcgttgttg ataagaaact agcagtgtct cctaccaaat tatccggaga
     7561 aaaacctgta gtcagcagat gtaatactga acgcaagaac gctgttgcaa ctccggccgc
     7621 tggaccgaat aagaacatgc tgatcaatac cgagatatca ctaaaatcga tcttcaaaaa
     7681 actaaaagcc ggcatgatcg gaaaagcaaa atactgtaaa actaatgcga tcgcagcaaa
     7741 catcgctact gcaaccattt tctgtacacg ggtgttcttc atttgaaatc ctcctgttag
     7801 gactcctctt cagcgaactt tttgacgttt ctctccaaat gaaaaaactc tattttccag
     7861 ggaaaataga gttagagtta tttgatcaag cgtcgtcaaa taagctctat cttctttatc
     7921 cagactatac tgtcggtatc ggaatttcac cgattcagct atttttttgc aaaataggtc
     7981 gtggactata accaccggtc gggaatttca ccctgcccct gaagacgaac cttatataat
     8041 ttttgtttac atattcatta tacatatcta ttcaaaaaac gcaacatcta acacttataa
     8101 aaagtaagtg ttcattttga gtggttcagc aaactgctga cttctttttt gttcagttca
     8161 cggtaatccc caggacgtag gccttgtaaa gtcagatctc cgtatttttc acgttttagt
     8221 ttttgcacag gaagaccaac tgcttgaagc atatttttca cttgatgatt acgtccttcg
     8281 tggatcgtca attccacgat actgtggttt gtcttaggat ccactgataa aatttggaat
     8341 ttagctggag atgtttttcg tccttcgatc tttattcctt ttgtcaaagg tgcaagcatc
     8401 gattttgtag cgatcccttt tacctttgca acgtaaactt tatccacttc atgttttgga
     8461 tgtgtcaggc gctgagcaaa atctccatca tttgtcagta gcaagatccc cgaagtatcg
     8521 taatccagtc gacctacagg atagatacgt tcttttacca tcggcaaaag atccgtaaca
     8581 acttttcttc ctttgtcatc tgcaacagca gaaataactc ctttaggttt gtacaataaa
     8641 tagtaaccgt attcttcttg ataaattggg acttcatcca cttccacagt gtcatgtttc
     8701 ccaactttta tccctaattc ccttacaact tgtccgttta cttttacacg tcctgcaagg
     8761 atgaattctt ctgcttttcg acgagaagtg atgccagcgt gggcaattac tttctgcaat
     8821 ctctccatta caattattct cctttattca ttccatcaaa gaatagatct ggtgacacgt
     8881 cttcttcaag tgaaatttcc atttcttgtg tatcaggcag ttcttctaat gatttcaaac
     8941 caaaataatc taagaagtag ccagttgttc catataatat cggccgacct ggtccttcta
     9001 ctctaccttt ttcttcaatc agtttatggg cagctagacg ctgtaccgct cctgaaacct
     9061 gaactcctcg aatctgctcg atttcagctc ttgtgattgg ctgtttataa gcgatgattg
     9121 ctaaggtttc gacggcggct tgagataatg tgtttgatgt cccttgcgca tatcgcttaa
     9181 gtaagggagc cagctctttt ttagtcgtta atacataatg gctttccgtt tcaaaaatat
     9241 gcaaagctga gtgcgagttt tgagtgtaag attcttttaa ttctttcact aaacttgtga
     9301 cttctgcttc gctgagattt aacagtccgc ttaattcttc attactgatc ccttcctcgc
     9361 caacaataaa aagaagggct tcaagttcac ttaatttcgt catgttcggt atctcctact
     9421 gctggataaa gcataattga ttcatagttt tctttttgtt gcgcaatgat ctgccctttt
     9481 ttcatcaatt ctagcaaagc cataaaagta gtgacaactt cacttttaga aggtgactca
     9541 aaaaaagaat cgaaagtaca gccatgcgca tttcttttta tacgctcttc gataaatacc
     9601 attcgttctt cgatcgttgt gtcatcgggc gtgatcgttt tttccacttt ttgagaaaat
     9661 ttcttacgtt ctaagatttt ctgcatggca cggatcaaat cgattttttt gacttgtcct
     9721 cgcttcaacg gcttttcagc atccgctaac ccatcgatgt tcataggttc ttttgtgtaa
     9781 taaagacttc gttcctctgc tttttctgtc agtctttcag ctgcatattt atatttacgg
     9841 tattctaaaa gctgagtgac caattcttct cgaggatctt cttcccataa ttcttcatcg
     9901 tctgtgacga attcttggac aggaagcaat gtcttgcttt tgattgccat caatgtagca
     9961 gccatcacta agtattctcc tgcaacagct agctcgagtg ttttcattgt atggatataa
    10021 ttcatatatt gctccgtgat cgtagcgatc ggtatatcat atatatcgat ttccatttgc
    10081 tgaatcagat gaagcagcag atcgagagga ccctcgaata catctaattt aatattgatc
    10141 tccgtcaact cattcactct ttcttctttt tctttgctag ccattttcca atgtaaggct
    10201 ctgtgatttc agttgcacgg atggagacat ccgggtactt ttcctgtaat tcatctaaca
    10261 tttgaaagcc catattctca ccgcgataag acggattcaa agaaatgtca tggatgatca
    10321 gctgatcgtt cgttgcccag taaataccaa taatcccttg aatgttggtt gaaccttctg
    10381 gcgtaaagaa aaaaagttca taatcgtctt cagattcgta cgtatcaatc tccttcaaca
    10441 aagaagtttt acctgtcagt ttcttatgga aactcaatag tcccatagca attttacggt
    10501 tttctttccg gtaatgtgtt aacatcttct caccttccta tgactaagcc cttggaaaat
    10561 gctgcttata aacatccgtc attcttttct tcgtgatatg tgtataaatc tgagtcgtag
    10621 agatatccgc gtgacctaac aattcctgta ctgtccgcaa atcagctcca ttttctagca
    10681 gatgtgtggc aaagctatgc cgcagcgtat gtggtgttac ttctttgtaa atcccagcct
    10741 ctcgtactaa ctgcttcaga tttttccaga ttccttgccg agaaagacct ttcccatgat
    10801 tattgacaaa tacatgcatt tcagatgcgt cctttacaag taatggacgt gcttcgtcta
    10861 agtagcgttc cagccattgg atcgcataat cacctaaagg aatgatccgc tctttatctc
    10921 cttttccaac tgtctgtacc agtccaagag aaagatgaag atctcccaat ttcaatccaa
    10981 tcaattcact gacgcgcatc ccagtagcat acatgacttc caagattgca cgatctctta
    11041 tccctaacgt ttttgtcgta tcaggtgctt caatcagctt ttctacttct gtcagagtca
    11101 atgtacttgg taatttctgt gctttcttcg gcgtatcgat atgttgcatc ggatcatgat
    11161 cagtgatacg ctcttgccgt aaaaactgat ggaatcttct gagacttgag atcatccgag
    11221 taacagttgc tgtcgctttt ttttcttcat gcaacttctc cagaaaacgg atgactaaaa
    11281 agcgatcgac atcctgccat gaagcaattt tctgctcctg tagaaaatgc aagtactgtt
    11341 ccaaatcacg ttcatagctt tgtcgtgtat tggcggacaa tccccgttca atattcaagt
    11401 agtggagata atcgttgatt tgctctttca taataatccc cctcatgcct ctctatcata
    11461 tcagataccg cttcattctg atagtctttt tccataatct gagcaaagaa aaagccgtct
    11521 agacactcag acggactggt ttcttttttc tttttcatag cattcctgac agattccatg
    11581 gaacgttagc cgatgatctt ttactaaaaa atgataacgt tcttctacta cttgctccac
    11641 ttcaagtaaa agatcctctt ctacttcctc gatcgtgccg cagttcaagc atagtaaatg
    11701 atgatggaaa tgtttggcgc cttcttttct caaatcataa cgggctaatc catcattaaa
    11761 acttacttta tcgacaattt tcaattctgt caagatttca agggttcgat aaacagtagc
    11821 aagtccaatt tccggactct tttttttcac taaaaagaag atttcttctg cagataaatg
    11881 ctctttctca ttttccaaaa gcacaagcag agtagcttct ctttgcggtg tcagcttaaa
    11941 ccccgcttca tgtagctgct gttttgtttt tttcatcgcc gaaatagcat tcatgaccat
    12001 ttactcaacc ccaacaattt ataataatta caaataaaaa aagatataac actatgttaa
    12061 ttaaaattat tataagctag ttaagaaaaa catgcaaggg attctcaatt agattttttg
    12121 actagttttg tcacaccgtt ttcttgtgta atcaatcctt gtttcaaaag attacctaat
    12181 gcgcgcttaa atgctccttt gctgatacca aaagctttca tgatttcttc tggatccgat
    12241 ttatctgtaa agttgatttg ctgatctgca gaacgttcta aaatggttaa aatcatttgt
    12301 gcatcatctg atatagcttc atatgctctt ggcttcaatg aaagattcag tacaccgtct
    12361 ggtcggacac caatcactcg accttttatc tgctcgccta gacgaggttc attatatcgt
    12421 tcagaaggat ggataaaccc aagatagaaa tcttccgtta aaacgtacgt acctgttaat
    12481 ttcaagcggt atgctgttcc tatcacatct ttgtttttca tttcttctgt tccatatttg
    12541 cttaaagatt tgaatatttt ttcatctgct aaactgcccc aaatacggtc ttttgcatca
    12601 actctaaggg aaatcatcaa gcgatcccct tttttaggcc atagctctgt cattgtcggc
    12661 aattcatcaa gagatacgac aaagtcttta tctggaagac cgatatcgac aaacgcacct
    12721 aaatcttttc gtgtagcagt aacgattcca aaagcgtaat gaccgatacg gcttttagga
    12781 atttgtgtag tgatccgatt ttcatgtttt tgattttggt aaccgaatcc ttcaactgct
    12841 tcaccgattt tgtgttcacc ttctgatttg cttaagccaa aggtttgtcc gtttttttgg
    12901 acaaagtagt ttttttcatt ttcatcaata ataatacctg taaatatagt tgctaataaa
    12961 tcgttcattt ttttctccct ctatagtgaa aggttttctt aatacatttc tttgctatca
    13021 taacataatg ttatctactt gaatagctga gccttggttt ggaaaggtga aaaaaggagt
    13081 atgacaacag ttgtgtcata ctcccctttt tcgaataaac ggtgttaaac ggcaggctca
    13141 cagcctcttt catttgccta aaattaattg ctcccatttc ctccgaacca tccagtttta
    13201 cagttgatgg ttacgatgta aaatggcaaa gcactttctc caatgccttt catcaatgca
    13261 gattttgttg aagtggcata tagattataa tagccttccc cattttcgat tctggctttt
    13321 tctaatctgt aacctccttc aacgatatat ccacgttgga tacatgtagc aatcactttg
    13381 ctttggacac ctggtgccca cgtccatgct ggattagatg catcggcaat atcacttgct
    13441 ctggcagatt tgattggctg attcgctgag tttgaagagg aaggggtcga ggatgccgct
    13501 tcttgctgtg ctgcttgtgc gaccgcagct tgttgagcgg cttgagctgc agctgctgct
    13561 tgagcggctt gttttgcttg ttcttcagct gcttttttcg cttcttctgc ttttttcttt
    13621 tcctcttctt cttttttctc tttatcagtg agcatcttat ctacttgttt caattgttca
    13681 ttcaactgag cagatagatc tgtatttttc actttttcta ctgcttcttt tgccgtcttg
    13741 tattggtcgc gtgttgctga atccactact tttccgtctt taaagactat agctgttttt
    13801 tctttagctg tttgcaattc agcatattga tttttagctt ctgtttgtgc ttgttgaatc
    13861 aattttccaa aatctgtgtt atccgtttcg attgcttgga tctctttatc tgctttcaac
    13921 ttgatgtcat ctgctagatg atcatcgacg atggcaggtg ctatgaacca ctcattcact
    13981 ttttggatat ctcggatctt agattggata tcttggtaag ttgtttctaa ctctgaatat
    14041 cctttttcat tcttaagact ggataaatca ttttttagtt ttgataaatc ttgatgaatc
    14101 atatctgcac gaataaattg atggtgatca tctgtataaa aggcagcaag tttctcatga
    14161 agttcttcca tttgttgctg tctttttgct tctgctgcta cttcggcttc tactttttga
    14221 tgatggtcat aataagccca gcttcctcca ccgagtagaa gtactgctgc taaaacgaga
    14281 taaggtactt tttttgattt tttcttttgc gctttatctg gatctgtttt ttctaagttt
    14341 gattcttgat gtgttttttc agtatctggc acgattgtta ttgatttcgc ttctgcttca
    14401 aacagcttag gctggttctc ttctttttct atttttgctt caagatcagt accctctttg
    14461 cttacagatt gattttcagc atcggattca ctatttattt catcgggctc tgttgacttt
    14521 ttgtctgtgt tttcgagtat ttcttttttc tctgcttccg gcagtttatt cgttttttcc
    14581 ttttctaatt gtttttcagt aaatacttca gttttttctg tgatatccgt ttttacgtct
    14641 tttattttta ctgtttcttt acctgtggcg ttttctctat cagagtcttt ttcagtttct
    14701 tgttcctttt ctggctctac tttgttttcc tgtgcaattt tttcactgat cattttgagc
    14761 agctctttcg cgtgctcttc ttttgtatct tcacgatgtg ctttgatata agcggatagt
    14821 atcgaatttt cttcctcatt atcgacgatt tctttcagtt cagctactct tcttttttgt
    14881 tttgattcaa gcgtttcttc ttgattcttt cctgattctt ccgaagtctc atgaacagtt
    14941 gctttcttct gttcattttt ctctatatta gttacttgat cgtgagcagg tggttcttcg
    15001 tcttctggtt ctgctttttc gaataattcc attacagatt ctagaggtaa atctttcaat
    15061 tccgaccatt cgattggatc gtttaattct gtatcaggaa agactgcatc ttcagttgat
    15121 ttatcctgca tagctgcatc tgtatttgtt tcttcaattg attcttttat ttgctgatct
    15181 tctgcagtta tttgatgacc gcagtctgga cagatagtat tctgctccat ttttttcgat
    15241 ccgcaatttg gacatttttt catcacttag cgatcggctc ctttactagg tttacgctac
    15301 catttaatct atcatattct atacgtcacg ccaatagctt atttttagga tttacttaaa
    15361 aataatgaat gaatttcctt cctatagaaa aaaaagcttg agactgcgta gtctcaagct
    15421 ttttttcttt taaaataaac caaacagttt tactgatttc tcttctggtc aatagtccac
    15481 gcttattcta agaaatcttt taattgtttt gaacgagaag gatggcgcaa ttttcttaat
    15541 gctttagcct cgatctgacg aatacgttcc cgagtaacac caaatacttt ccctacttct
    15601 tccaatgttc tcgtccggcc atcatctaaa ccaaaacgta agcgaaggac attctcttcc
    15661 cgatcagtca atgtatctag tacatcttcc aattgttctt ttagtaactc ataagctgcg
    15721 tgttctgctg gacttgttgc ttcctggtct tctatgaaat cacctaagtg agagtcatct
    15781 tcttcaccga ttggcgtttc aagggaaaca ggttcttgcg cgattttcaa gatttctcgg
    15841 actttttctg ttggaagatc catttccgca ccgatttctt ctggcgtagg ttctcttcca
    15901 aggtcttgca gcaattgacg ttggatacgt atcaatttat taattgtttc aaccatatga
    15961 actggaatac ggatcgtacg tgcttggtca gcgattgctc gagtgatggc ttgacgaatc
    16021 caccatgtag cataggttga aaacttaaat cctttgcggt agtcaaattt ttcaactgcc
    16081 ttcatcagtc ccatgtttcc ttcttggatc aagtcaagga actgcatgcc tcgtcctaca
    16141 taacgtttag cgatacttac tactaaacga aggtttgctt ctgccagacg ctgtttcgct
    16201 tcttggtcgc cttcttcgat tttcaatgct aacgctactt cttcttccgc agttaaaagg
    16261 gagacacggc caatttcttt cagatacata cgaaccgggt cattgatttt tacaccggtt
    16321 ggcgcagaaa gatcttctgt ttttgcttgt tcagcttttt tctcagcact cttcaagctg
    16381 tgaattgatg gatcaccatt ttcatccacc acactgatac ctgcgtcttc aatcttttgg
    16441 atcaatttgt ccatttcatc tgcattcaaa gtgaatggtg tagcaagctg attggataaa
    16501 tcatcatata caacttgtcg tttgggtttg ttttctttga tgaaagctgc tactgctgct
    16561 tcatacgttt ttttatctgt tccatttgcc ataaaagaag gccccccttg agtagctatt
    16621 tggcttgttt taactgtttc gttaaattga tgatttcaat cgtcaattca agctcaagct
    16681 gtttgtttcc agttcgtctg gcttcttgct gcatttgttt ttttaatgtt atttcatcag
    16741 ctaagccaga tttgctgatc acatctagca agtcttggat ttctcgtggc gaactttctt
    16801 ctgccaccgg taaatattcg atttccacca ccaaccgcct taaattttca tcttgcaaaa
    16861 agtctaaaaa ctctgcaagg ttgaattcat aatgttgtga gacatatgca tcgaataaaa
    16921 aataaacttc tgcatatgca tcatgaataa actgaaattc tcgttctttt aaaatattac
    16981 ggacagaaac ttctttaaat gcacgatata atagaatctg ctctgccttt tctacttgcg
    17041 tcaaaggtct ctttttccgt gcagtttctt gtctcgtaac ctgagtgtgt tgactttcct
    17101 gaggttcttg acgattttgc tgatttgtcc ttcgaagatc gcgcagttgt ttttgtatcg
    17161 tctctctgcc gatctgaaac tctgttgaca gttgagatag atacatatct tgttcgattg
    17221 gtgaaacaac tcggctaagt tcaactagta attcttcgag gtattcgatc ttgtcttttt
    17281 cattatctaa atttttccct tgttttaaat aacgtgattt aaaagtaaag actgtttcgc
    17341 gcccatgagc cactaattct tggaaagatg cttctccata cttacggaga tattcatcag
    17401 gatcaagctt ttctggaacg actacgacag aaagtgctaa tcgactgttt tgccgaagca
    17461 attcaatccc tcgattggtt gcttcaaaac ctgcgttgtc tccgtcatag caaaagacca
    17521 attctttcgt cagcttttcc atttgttgga tctgttgagc tgttagactt gtccccatag
    17581 aagctaatcc agttttgata ccagcctgcc atgcagcaat cacatccata aacccttcga
    17641 acaacaaaat ttctccgttt ttccggatat cgcttcttgc tttatcaaga ttaaataaaa
    17701 cttgtctttt attgaacagt tctgtttctg gactattcaa gtatttgggc tgatcttttt
    17761 cctgcccttt ttcaggtgca agccagcgtc ctgaaaaacc gatcgtctgg ccttgagaat
    17821 tacgaagtgg aaacatcact ctttgataaa aacgatcaga catacggcca tcatcatgcg
    17881 tgacaaacaa tccagagcgt tctaacaatt catttgaaat tgattcattc ttgaatactt
    17941 gctgaagaaa agaacgctca ttaggtgcaa aacctatgtt gaattcttca attaattcta
    18001 aagacaaccc acgactttgc aaatattcta aagctggctg tccagctttt gtatgcaata
    18061 gcatgtgatg atagatttcc gctgcttttt catgagcagc aatcagtttc cccgtagcag
    18121 attcaggatt ttggacagct atagtacgct gacgccattg atcttctaac ggtatctgtt
    18181 cgaagtctgc cacttttacc actgcttctg gaaaacttag accttctagt tcttgaagaa
    18241 aagtaaacac gtttccgcct ttaccacaac caaagcaatg aaaaatctgc ttgtcttctg
    18301 caacagaaaa agacggtgta cgttcttcat gaaaaggaca cagccccaag taatttttac
    18361 cagacttttt caactggaca tattgtccaa tcacctcaac gatattcgtt tgactgcgta
    18421 ctgtttcgat aacctcttga ggaatccgtt gagccatttt ttcaccccct gctctattga
    18481 tatcttttgg gtttaacaga agatatttca ggagaataac cggtaaaaaa tcgcactaac
    18541 tgaaatcagt gcgattttaa aggacacaat tatacatgtt tgattgtatc atatttcatt
    18601 gctttttcaa gtataacaca tttctatctc attaagcatc aatttgctac tcttttcagt
    18661 aactgatttt gaatatcagc cttccagtac aatactcgaa gaacaatatt tacgagcatg
    18721 aatacaaaga agtatcctac gctctctccc aaccctaagt ttacttccaa aattccatgg
    18781 aacagcattg cagctacata tatccctacg atcgtcgtta ctgctaggaa gatgcgcaat
    18841 gggttgaagg gataacaagc ttttacaact gccatgcaac tgatcccaat cagcaagtaa
    18901 tacatcaaag tagtagtttc agcatttccc catgcgaatg tttttccaag tagatacacc
    18961 gcaatgatat tcactactac aagcaaggca tttggtaaag cattaataag tgctgtaggc
    19021 aaataacggt aagtgatttt tcttttatct tgttcaaaag ataaaaagaa ggaaggatac
    19081 ccttcaatcg ctaaatcaat cagcgtgatt tggataggga taaacggaaa tccaattgct
    19141 gtaacggcac atataatcga taaaataaat gaataaatcg ttttgataaa aaagatgcct
    19201 gagactttcg tcacattgtt gaccactcgg cgtccttcaa acaggacttc tggcaatgta
    19261 gtaaaatcag agtccaacaa taccagattc gcaatctgac gtgttgctcc atcaccttct
    19321 gccatagcaa tgctgcaatc tgcttctctt aacgccaaaa catcattcac accgtcgcct
    19381 gtcattgcaa ccgttctgcc gctttctttc aattcattta ccagcaattt cttttgctgc
    19441 ggactcactc gtccaaaaac cgtatagcga tgagcagctt ctcgcacttc catttcttca
    19501 gtaatttgag aaagatcgac atacgcatca taattcggta atcctgcacg tctagcgata
    19561 ttggagacag taaaaggatt gtctccagaa atcactttca gatccacacc ttcctcatga
    19621 agataagcta gtgtttcttg agcgtttttt cggattggat catcgatttc aaacagagca
    19681 accggctcaa caaatgctgg tttttcttcg ttcaattgct gatttggagc gatccccaac
    19741 ataagtacgc gatagccatt cgcttgggct gtttttagac tgtccggaag ccgatcttct
    19801 tccaccaaac gttcaggcgc tcctacgtac acgactccca gttctggaaa ttccatcgcg
    19861 ccccatttgc gatcagaaga aaatgcgact ttgtttgtca catcataccg attagaaagc
    19921 tcaaaataat ctctcatagc ccgcatagtg atgttgttat cactgctttc tgccagatac
    19981 gtccccataa tttctgggat ggctttctcg tacagcggat gtagtgcttc tacccgctgg
    20041 atactcattt tcccttcagt aatggtccct gttttatcca agcataatgt atcgacatgg
    20101 gccagcgttt caattgaata catgtcttga acaaggattc gtttttttgc cagtttggtt
    20161 acccctgtcg ttaatgcaat acttattagc aataccaaac cctttggaag catgcctaac
    20221 aaagctgctg cagatgcaat aacagaaatt ttgatagaag catcgcggat gaacagtgct
    20281 tccaaaaata gtatgatccc caaaggaata atcacgaaac tagtgaattt ggatactttg
    20341 cgaatcgaat ctacaagttc agaacgaata gctttgtgag tctttgcctc gctagtcaag
    20401 cggacagcat aattatctgc acctactcgg ataacttcag ccatgacaga accgcttgtc
    20461 aaaaagcttc cagaaagcaa ttcagctcca gtttctttga caatcaaatc agattcgcct
    20521 gtcaaaagag cttcatttgc ttctgcccgt ccagatataa cctgtaaatc ggctggtatc
    20581 tgttctcctg ctccgatttt taccaaatct cctaatacca gctctttagt agaaatcgat
    20641 tgttctttac cgtcccggat cactagtact tctgattggg aaacaatcga taatttccgt
    20701 acaagatttc ttgcatgtat ttcttgataa attccaataa cgatattgac gacaataatt
    20761 gctaaatacg ccatgttgga atacgcacct acaaataaca gacaaatccc aataccaaag
    20821 ttcagaaaat tgaataacgt caatatatta tcgctgaata tttgttttgt actttttgat
    20881 gcatcttcct ggtagtcatt ttgctggcca gaagccattt tctgaactac ctcttgctgt
    20941 gtaagtccat tcattttctt tttctccatt ttccgccaac tttcaaaaat aatcacgtgt
    21001 ttaagtctag cgtgttccaa gattaaaaac aacttgtttt tataaaattt atagaaaaac
    21061 acacgaatga ttttacaaaa aagatgccaa cctttttgtt tgaatcaccc gtgtgctgtt
    21121 tttattatca atctatcttt acttatattg ttcctccaaa cggctcatcc accaacctag
    21181 tgctgtaccg gctataaaaa gaacaggaca agctagtacc ccagcaactc ccaatcccgc
    21241 gtaatcggta ggaatgatca taatcgttga agcaaaaact acacctaaaa tgaaatggaa
    21301 tagcttgcta tatgcctttg agaaaatgta atccatgatt tttgacaatc caagaacaca
    21361 aagaatccca ccaattccga tcggcacaat cacttcaagt cgtacttctt taaatccgtc
    21421 agccatcgct ttatacaatc ccatatacac caaaaaatta gaagggctca atcctgggac
    21481 gatcataccc aaaccaatca atccgccggc aatcagccat gttccaaaat tctgatcgac
    21541 ttgcccgtca aataattgag cgccgtataa taaaaacaaa taagccagaa caaaagtaac
    21601 aaccatgatg atcacatcag aagtatctct tccttttttc cctgcttctt tccataacgc
    21661 aggaacagtt ccagcgatac atccgacaaa aaaccataat atcgttgttt catacgcacc
    21721 taataaaaaa ctgactaaaa aagaaagtag aaagatgcct gtcactccgc ctagaccaac
    21781 aggcagaaaa aacaaaacat tttctttgaa attttttgta aggtgggcta aaaaagaaat
    21841 cagccgctca tacatgccaa agacagctgc taatgcacca ccgctgactc ctggcaagat
    21901 aaatcctgaa ccgataaaca ttcccttcac aaaccgtaac atccagtctt tggttgtgta
    21961 ccccacttct tgattttcca ttttttgcct tttttccact atttgcgtac tccttctttc
    22021 atttaatttt attcatgatt gaacatttcc tgctatttta cttaaagact ttttcatagg
    22081 tctctattat tttttcattc attttgacaa tatcaggata aaacatgtta cctccattat
    22141 gatagagata gccgccattg taaagcaagg actggatccg ccaatatcgg tattgtttcc
    22201 cttcctcatt tcctaaaagt gggctcagca catctttaga atacgcttct gctaattcta
    22261 ctgtgttttc tccgccatga ttttttacat aggcaatata atctttccca aaattatatg
    22321 cttggacagc tgtccataaa tcgcatcctt gtttctttgc ttctactatc atttccgcca
    22381 aatatttgac accttgatca atactgtcag ctggattatc aatgatctca gcttctccat
    22441 gcagactttc cgagctctgc atgagatctg tcccttttcc ttttgattcg gtcaatatta
    22501 tcgccttgat caaattctcg tagttttcca tatgataatt ttttgcagct gttgttattt
    22561 ctatttgata gctttccact cgttttaccg aacgataagt tcttcctcat aaaaacaaca
    22621 ccgcaccaat aaccgtcaga atgatcatgt aaaaaagaat acggataata gataatcgtt
    22681 ttcgcttcat ttcatcacct agttattttg acatcttttt ttatcttact atttctttat
    22741 cttcttggct atttcttcct tgatttctgt gtacgcctta agaaaaaatg aattttcctg
    22801 tattttttga catcttacga aaatgatcgt tgtttttcag taaaaacaat tgcccaatga
    22861 ctgatataat cgttatactt tacacagtag gtgattatgt gaaaaaagaa aagaaatatg
    22921 caaaaatgcc agatgggagc gaaatttact atgaaaagag cggtcaaggc ttccctctct
    22981 ttttactgca tggcaatgac ggcagcggcc gctttttttc agaacaggtc cctgtactcg
    23041 aacgctacta taccgtgtat ctagtagata gccgaggaca tggtcgttcg acaaacgaag
    23101 catctatgtt gaattttcag ttaatggccg aggatctgaa tacgatcatg ttgctggaaa
    23161 aaatcgatca ggcagatttt cttggattta gtgatggagc aaatctagca ctggtatttg
    23221 ccagcagctt ccctaaaaaa gttcatcgat tgattttaaa ttctggaaac acgcttgtta
    23281 aaggcgttcg tttttctgcc agagtcatca gtaatattca ttatgcatgg gtatggttac
    23341 tctctttatt tcgcccaagt cttcgcaaaa atcttttagt tatcaaactt ttgctgcatg
    23401 acatcgggct tacagaaaat gatttaaaaa aaatcaactc ccccactttg atcatcgtgg
    23461 gaaaaaaaga tgtaatcaag ctaaaacatt ctttgtatat agctaaaact ataccaaaag
    23521 cttcctttgt gcttgtgaaa gaacaaggac atgaattagc tagaaaagat cctgaacgct
    23581 tcaatcgaga agttcttcaa tttctttctg aaacataact attaggaata gaaggtgatt
    23641 tatttgttaa aaaataccat acaatggctg aaaaaccacc taggactgtt caaaacaatc
    23701 tttttgattt ctgtcattgt cattattgtc ggtgaattga tgtccatcgg taaaactcta
    23761 tctatccagc aattaggaga aacgtttgcc actatacctg tatggaaaag cggactaatg
    23821 ctattgattg gtcttatctc tgtgttacct atggttggtt atgatattat tttgaatcgg
    23881 atgcttgaac aaaagcagaa tcctcgttac ctgtttgaga caagctggct gatcaatacg
    23941 atcaacaata ttgccggttt cggcgggttt gttagtgtgg ggcttcgctc tgaactatat
    24001 ggacaaaaga aagagagcag aaacgtgatc caagcattat cgaaagtttt cttgtttttg
    24061 atggctggac tttctattta cagtctgctt tcttttttac ttgtagtctt cacgccagtt
    24121 gctccttttt tgaagcaata ttggatatgg ttgatcggcg gcggtctata ttttcctgtc
    24181 gtctttttat ttactacttt caaaaagaaa ggattccttg gtggtacctc acttaaaact
    24241 caaggacagc tattgctagt ttcattgttg gaatggaccg gtgtcctgtt tagtttcctt
    24301 tctgttggtt atttaatgga aatccggatt gatctgtggc aaacaattcc attattcatt
    24361 gctgcttcag tgataggaat cgtgtctatg attccaggag aaattgggag tttcgatgta
    24421 atgatgatta tcgggttgtc cgctattggt gtgccaagag aaatagtcgt tgtgtggatc
    24481 ttgctctatc gcctgttcta ctacatcatt ccgtttttga ttggaatcgt ctttttcttc
    24541 aaaaatatcg gttccacttt tgatcagcgt tattctggta tccctaaaca attagcaaca
    24601 gaaattgcgc ataaaatcgt ggttgtctta ttatactttt ctggaatcat gctagtactt
    24661 tctgccacta tcccgcaagc ttttacagag tttcgctggc ttcatagttt gaacccattg
    24721 aaatttcatt ttattatcca atttcctagt atactattgg gatttctttt aatcattatg
    24781 ggcagaggga tcgcagcacg tgtgaaacga gcatatttgc ctacaatctt cttgattgtt
    24841 ctagctttac tttatgtttt attaagtgat tttagtttca caccggtggt tttcttgtct
    24901 attctgcttc tgatcattct tgcttctaaa aacgaattat ttcgggaaca attgatctat
    24961 tcatgggagt ggcgtacgat cgatggaatc attattggtg cactgtcctt gctttacatc
    25021 gttattgggg tatacaatct gccggatttc cctcatcggc gtcaccattt tatttccttt
    25081 ttcttatttc cttctgaaaa gatttggttt tcgggattgt tggccatcat cgctgttagt
    25141 ttcatgatcg ttctatttgt tcatttcctt caaggagaaa agaaacagat tggcgaagcc
    25201 tttaatgaag aaaaggccct gaagatcctt acaacttatg gaggaaactc cgatagtcaa
    25261 ttgatcttct taaaagataa gcggatgttt gcctatgaaa aagacggtga accaactgtt
    25321 cttctccaat tcgcttgctt caataataaa tgtattgtaa tgggtgatcc ttctggtaag
    25381 aaagaagatt ttccagaagc aatcgaagct tttatcgaag aaacagatcg actatgctat
    25441 ttaccagttt tctacgaaac aagcgaagag attgttatga ttttgcatga attcggctac
    25501 gatttcatta agatggggga agaagcttat gtagacctga atagttttac aacttcaggg
    25561 aaaaaaatga agggcactcg tgctgtcttg aatcggatcg aacgagaagg atttacattt
    25621 gatgtcttac aaccaccatt ttctactgag caaatgagta ctttcaaaaa tatctctgat
    25681 aattggttgg gttcacgaaa ggaaaaaggg ttttctttag gctttttctc tgaagattat
    25741 ctacaaagag cgcctattgc agttgtcaaa aatacccaag aagaaattgt cgcttttgca
    25801 acgatcatgc ctacttacac gaacaataaa gtaggaacga ttgatctgat gcgatatgat
    25861 tctaaaaaag caccttctgg cagtatggat ttcttgttct tgcatttgtt tgcctatatg
    25921 aaagaagaac atatccaatg gttcaattta gggatggccc ctctttcaaa tgtcggaact
    25981 tccagaaaga gttttttaca ggaaaggatt gcatacttgg tttacgagtt tggttctcat
    26041 ttttattctt tccatggatt aagagaatat aaaagcaagt acgctacaaa ctgggtctca
    26101 cgttatactc tatattctag agatagttgg attgcatatg ttatgattgc tttgctgatt
    26161 attgataatg cgccagttga gcagacacaa ggtagaataa gtggtttgaa aaaatggata
    26221 cgaagaaagt attaaaaact gcataccgat agatgaacac tctcatgatg aataaaagag
    26281 actgaagtaa aacgaaagtt catgcttcta caatctcttc ttatacaatt gaagaacaaa
    26341 gagcggtcca aacagaaatc ctgtttggac cgctctttta ttttaaacat ttttcattac
    26401 caaaatattc gagtcgcgtt tcttatgctt cgatctctgt aacgatacct gaacctactg
    26461 tccgtccgcc ttcacgaatt gagaatgtcg ttccgttttc aacagcgatt ggatggatca
    26521 agtcaacatc aatcgtcacg ttgtcaccag gcatgaccat ttctgtatct tctggcaatg
    26581 tgattgttcc tgtaacatca gttgtgcgga agtagaactg tggacgatag ttgttgaaga
    26641 atggagtatg acgtccacct tcttcttttg tcaacacgta cacttctgct ttgaattttg
    26701 tatgtggagt aatggaacct ggtttagcaa gtacttgtcc acgttcgata tcgtcacgtt
    26761 ggatcccccg taacaacacg cctacgttat ccccagcttc cccgtaatct aacgttttac
    26821 ggaacatttc tacacctgtt acaactgctt tttgtgtttc aggtttgatc cctacgatct
    26881 ctacctcatc accgacacga acagcaccac gatcaatacg acctgaggca acagttcctc
    26941 gacctgtaat tgagaagacg tcttccactg gcaatagtaa tggtttatct gtatcacgtt
    27001 ctggtgttgg gatatattca tctactgtat ccatcaattc cataatagca gcttcagcat
    27061 ctggatcgcc ttgcaatgct tttaatgcgg aacctttgat cacaggagtg tcatcgcctg
    27121 ggaaaccata ttcgctcaat aactcgcgaa cttccatttc taccaaatcg atcaattctt
    27181 catcatcgac taaatcaact ttgttcaaga aaacaatcag gtattttaca ccaacttggc
    27241 gtgacaataa aatgtgttca cgtgtttgag gcatcggacc gtcagttgca gaaacaacta
    27301 agattgcacc atccatttgt gctgcccctg taatcatgtt tttcacatag tccgcgtgtc
    27361 ctggtgcatc aatatgcgcg tagtggcgtt tttctgtttc atattctacg tgtgcggtat
    27421 tgatcgtaat cccacgttca cgttcttctg gagctgcatc aatactagca tagtcttgag
    27481 gatttgctag gccttttttg cctaatactg tagtgatcgc agcagttaaa gtagttttcc
    27541 catggtcaac gtgtccaatc gtaccaatgt taacgtgtgg tttacttctg tcataatgtt
    27601 cttttgccat aatttacaaa cctcctaaat aatatagatc actgaaaaat ttcagctctc
    27661 acctttttat tatagtcttt ttttgactaa atcaaaaaga atacgtccga cttacttttt
    27721 gtaagattcg aactaagctt attatacgtc aatattggtc aaagtcaact aagagcactc
    27781 gtctgtctta tacgcgaaaa aagtaccttt tataaataaa aaaatgtgtt ttttgagaaa
    27841 aacttcaaga tagtccttaa ctttcttttg aagcaataag aacaaaatga ggaaaagttt
    27901 aaaattcagc tgttgccaac aactttcaat agacgaaatc ttctatttcg ttaataataa
    27961 ggaaagaggt gaagtacatg aaaaaattaa ttggcgtact tgtcgtttta ggcatatttc
    28021 tcggcggaag ttttgcagct tatcattatt tttacggcgg cgaagcttat tatacaaaaa
    28081 tcacgacgaa tggcgaaatg tcagctaccc aagcagataa cggagagaaa ttcacgactt
    28141 atacctacaa gcaagcggct tataataaag atggtgaaaa aaaacaggtg acgcttcgcg
    28201 aagaaagaga acatccatta aagatgaatg cgtatcttaa actcaaagtc aatcctcgta
    28261 aaggtgtatt aagctgggaa gaaataaagg cttctgaagt gcctaaaaat gcggcagaaa
    28321 aaatcgataa ttagtaaatg gtcttaaaat tttattagat aaaaagaggc tgggacagaa
    28381 gcgtttaact ccaagaaata agaaggagtt gcttctgctt ccgccgttta tacgtgttta
    28441 gagcgtgaga caaaagtgtt ctttactttt gtctcacgct ctttttttgt tatattcgtc
    28501 ttttccgatc cttctcttga cacaattcat ttaactgatc actggtactt gaacacctaa
    28561 tattctagtc atttttataa acgattcaat acttcatcca catttttgat catcacggat
    28621 atcgtaccat ccggattatt cacaaattca atcaaatctg ggttgcgata tacatctact
    28681 ggtacgatca gttcgatccc gtttgatagc ttgaattttt gttttccaaa ttttttctca
    28741 gaaatttctt gtacttcttt tacaggaggt gcttctggga caaatccttg ctcttgtact
    28801 tcttctttaa aagccatttt tgccgtgatg ttttccttga agactttttc cgcaatcatc
    28861 tcatgatcca accgaccttt ttcttctatc gtatcataga cagcttcttt caaatcagcc
    28921 atgatatcaa attcttctgt ctcaaatttt tttccaagat gcttggctac tttttggatc
    28981 acttttacat tttcttctaa agaaggtgca ggaacacttt cgatcactct tccagaaaaa
    29041 taaagctctt ttttgccaga aaactcatat tttttttcaa ttaattcgta ggtccaatca
    29101 gtcaaattca cagcgaatgc ttcatctgct ttttgtgttt tcgcccctag aattgctcga
    29161 ttcaaaatca agcggttgtc gatccctgct tcgtctgctt caacaaagtg agtgtaagcc
    29221 tcacgataat tgactttcaa taaagataag tacatcactg tatctaattc atacaagaca
    29281 acaaatacat ctgcactagg tgcttcttca ctttcttggt agatatcgaa ccaccgctga
    29341 acgattgctt cacttgcttc cacaaaattt tcttgagcga ttttaagtga ttcaacgatc
    29401 atgctttctt ctgctagttg tccagttttt gtttgagcag aagagatttt ttggatcttc
    29461 ttttgaagaa aatcacgaat atattctttt gtcagatcca gctctttttg tgaaaagact
    29521 ggagaaccag tttctctgtc aataatatgc agaattgctt tttttaaata gatatccatt
    29581 ttctcattcc cttctgtctt agtttacgga aaaaaaatca aaaataccag aatcaaaatc
    29641 attttctttt aaacaaaaat ttcaagagta gaaacaaaat ggattctttt tttcgaaaaa
    29701 tgcgctacac ttatagttga acgaataaaa aaggagctga aagtatgaat tcattaacaa
    29761 gcacttatcg tctatcaaat ggttacgaaa tcccggtagt aggattcggc acatggcaaa
    29821 cacctgatgg ggatgtcgct gtttcctctg ttaaagaagc gctggctgca ggttatcgcc
    29881 atatcgatac tgcccaagga tacaagaatg aagaaagcgt cggccaagcg attaaggaaa
    29941 gtggaattcc tagagaagag atattcttga caacaaaatt atggaatgca aaccacagct
    30001 atgaacttgt gatgtcttct tttgaagaat cattgaagaa gctccaaaca gattatttag
    30061 atctgttttt gatccactgg ccaaaccctg ttgcttttcg tgataattgg gaacaagcaa
    30121 atgcagatac atggcgagca tttgaagaac tgtatgaagc aggtaaaatc aaagcaatcg
    30181 gtgtgagcaa tttcttaccc caccatctag atacactagc aaaaacagca aaaattatgc
    30241 cgatggtcaa tcaagttttc cttgcaccag gcgaattaca gacaactgta gttgagtatg
    30301 caaaaaaaca tgatatgatc ctcgaagcat atagtccatt aggcactggt aaaatcttcg
    30361 atgtgcctga aatgaaacaa atcgctgaag cacatgacaa gacgattgca caagttgctt
    30421 tgcgttggtc gctgcaacac gaattccttc ctcttcctaa gtcagtgaca ccaagcagaa
    30481 tcaaagaaaa tactgaatta tttgattttg aattaacaga agaagaaatg aaacaaatcg
    30541 atcagttaga tggtgtagtc ggcaaagcaa aagacccaga tactacccaa ttttaagtcg
    30601 aaaggtgatt ttatggatcc aatcgaacgc ttgaattctc tctcggaaga agttacccag
    30661 acttttcatt ccgattttgt ctttttgatc gatgcagaga aaatccaaca ttttcctgca
    30721 agaaactgga cacatgatca aatcatcgaa gaactgaaaa aacggttcga tcattcgcta
    30781 atggtcaaac cctggcacga acatgaagtc atttattcac ctgaactacc tgtttttgcc
    30841 ttgataccga aaaaatagaa agaatggaac ggattatgta tatatacata atccgttcca
    30901 ttttttattt ttctttcaaa aaacgggaaa atacgcaaat ttttctgttg taatttgcgt
    30961 atacgcaagt ttttttgcat tactcctttt catttggctg tttttttctt ataatcgaaa
    31021 gggtatgagc gaaggagaga acatatgaag aaaaaacaga aacaaaaatt attaaatcaa
    31081 ttccgtcctt cattggatgg tgtaagagga caattattcc gttctctaga agaagagagc
    31141 ttgcgacgtt atggtttgcc gttacaagtc atgcttgatc ccaaaaaccg tcaaatctta
    31201 acgatcggat tagctgggaa aacaaatgaa gatacacgga tcaacgtgcc aatcgatgac
    31261 aacttcaata ctgtattaaa gagaattcgt tcaggagaaa acgggatttt cgaacgattc
    31321 cgtgacaatc ttcttattga aatcgtgtct tactggaatg atcaacgatt gaaaaacgat
    31381 gaaccaactg cgcaagctgt tgcgacacca gttacagaag aaacagtcag tgtgccagaa
    31441 gaaaaaacgg aaaaaccaaa agcggacaca actgaaaata cacgctcaac tgatacgaat
    31501 gccgctttaa gttttgctga tttttcaaaa gccgttgctg agtatcctaa attttacaca
    31561 gaacaaaatg aacatgaagt agttattaat gaaaaaaatg ctgatgaacc tcgtaaatta
    31621 gcaactattt ctatgactac tgaaaatgag ttcgttatcg aaaaagcact cgaacggaaa
    31681 tacaaagtca aattgacttt gattcctttg atcgaacaat ttgcagcgac agcgattact
    31741 gatcgataaa aattctattt gtcataaaag gctgggattt aaaatcccag cctttttagt
    31801 catataataa tttctacagc aagtaaaaag aaattccttc taacatcagg ctcaaatatc
    31861 agcttgacct gtccaacaaa tcacctatga tcctacaatg ttaggcgact tctcttctac
    31921 ctgaagatat cttggagttg cctgatttct taagatgcct aaccttaact ataaaaaatt
    31981 ctaataataa acatattttc tgatagagaa aaaag
//
LOCUS       DACBYO010000027        31004 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.027, whole genome shotgun sequence.
ACCESSION   DACBYO010000027 DACBYO010000000
VERSION     DACBYO010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.027"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(395..2470)
                     /locus_tag="IVD26_001187"
     CDS             complement(395..2470)
                     /locus_tag="IVD26_001187"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAP6079175.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKKSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2472..3389)
                     /gene="glyQ"
                     /locus_tag="IVD26_001188"
     CDS             complement(2472..3389)
                     /gene="glyQ"
                     /locus_tag="IVD26_001188"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAP6079176.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            complement(3773..4585)
                     /gene="recO"
                     /locus_tag="IVD26_001189"
     CDS             complement(3773..4585)
                     /gene="recO"
                     /locus_tag="IVD26_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAP6079177.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            complement(4728..5627)
                     /locus_tag="IVD26_001190"
     CDS             complement(4728..5627)
                     /locus_tag="IVD26_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAP6079178.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5642..6043)
                     /locus_tag="IVD26_001191"
     CDS             complement(5642..6043)
                     /locus_tag="IVD26_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAP6079179.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(6021..6497)
                     /gene="ybeY"
                     /locus_tag="IVD26_001192"
     CDS             complement(6021..6497)
                     /gene="ybeY"
                     /locus_tag="IVD26_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAP6079180.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6514..8706)
                     /locus_tag="IVD26_001193"
     CDS             complement(6514..8706)
                     /locus_tag="IVD26_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAP6079181.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHAVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8730..9701)
                     /locus_tag="IVD26_001194"
     CDS             complement(8730..9701)
                     /locus_tag="IVD26_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAP6079182.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10407..11786
                     /gene="brnQ"
                     /locus_tag="IVD26_001195"
     CDS             10407..11786
                     /gene="brnQ"
                     /locus_tag="IVD26_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAP6079183.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(11942..12388)
                     /locus_tag="IVD26_001196"
     CDS             complement(11942..12388)
                     /locus_tag="IVD26_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAP6079184.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(12415..12591)
                     /locus_tag="IVD26_001197"
     CDS             complement(12415..12591)
                     /locus_tag="IVD26_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAP6079185.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(12753..13181)
                     /locus_tag="IVD26_001198"
     CDS             complement(12753..13181)
                     /locus_tag="IVD26_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP6079186.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            13273..14133
                     /locus_tag="IVD26_001199"
     CDS             13273..14133
                     /locus_tag="IVD26_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAP6079187.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(14217..14510)
                     /locus_tag="IVD26_001200"
     CDS             complement(14217..14510)
                     /locus_tag="IVD26_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP6079188.1"
                     /translation="MPDTQKTKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAIIQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(14583..16310)
                     /locus_tag="IVD26_001201"
     CDS             complement(14583..16310)
                     /locus_tag="IVD26_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAP6079189.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            complement(16523..17449)
                     /gene="trxB"
                     /locus_tag="IVD26_001202"
     CDS             complement(16523..17449)
                     /gene="trxB"
                     /locus_tag="IVD26_001202"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAP6079190.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(17594..19027)
                     /gene="ascB"
                     /locus_tag="IVD26_001203"
     CDS             complement(17594..19027)
                     /gene="ascB"
                     /locus_tag="IVD26_001203"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP6079191.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(19027..20430)
                     /locus_tag="IVD26_001204"
     CDS             complement(19027..20430)
                     /locus_tag="IVD26_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP6079192.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            20660..21562
                     /locus_tag="IVD26_001205"
     CDS             20660..21562
                     /locus_tag="IVD26_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP6079193.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(21603..23489)
                     /locus_tag="IVD26_001206"
     CDS             complement(21603..23489)
                     /locus_tag="IVD26_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6079194.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(23586..24437)
                     /locus_tag="IVD26_001207"
     CDS             complement(23586..24437)
                     /locus_tag="IVD26_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6079195.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            complement(24895..26679)
                     /locus_tag="IVD26_001208"
     CDS             complement(24895..26679)
                     /locus_tag="IVD26_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079196.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(26679..28430)
                     /locus_tag="IVD26_001209"
     CDS             complement(26679..28430)
                     /locus_tag="IVD26_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6079197.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            complement(28572..28796)
                     /locus_tag="IVD26_001210"
     CDS             complement(28572..28796)
                     /locus_tag="IVD26_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAP6079198.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            29047..30633
                     /locus_tag="IVD26_001211"
     CDS             29047..30633
                     /locus_tag="IVD26_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAP6079199.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
BASE COUNT         8673 a         6648 c         5522 g        10161 t
ORIGIN      
        1 tctgattgac gtcataaaaa gtagctttga attcataatc gtttatataa cgattaatag
       61 aaaacaatat agtatttagt gttcatacaa tgattctaag atcattttga attaatcagt
      121 cttatagttg atttctaaat tgtcatatat tattaaaaat ttttgccatt taaaaagaaa
      181 agcgacagtt taccaataaa tttcaactga attatctaaa agtagatcag ttagtttaga
      241 taattcagtt gaaattgacc gactcaaatt acttgtataa tacctaggaa aaaattaact
      301 agcaccacgg gtatagttat ttatatttat aacaaataaa ccagagaaat agcctatttt
      361 gtgcctattc tctggtttat ttacatatta gaaattattt tgtgatgatt tgatctaaac
      421 ttgctagcga caaagccatg gcagcaattt gacttaattg cgttaatcgg ttcttacgta
      481 ctgctggttc ttctgccatg accatcgtct gatcaaaata attttcgatc agtgggcgaa
      541 ggcttacaag ctgatcataa ttttcgttga tcgtttggtc agcaaagctt tttttcattg
      601 cctctactgc tttgtgcagt tctttctccg cttcattttc gaacagttca gggtctactt
      661 ctgattgttt ttcaagctcc gcttttttcg ctaagttcac gacacgtgtc aaagcttcca
      721 tcgatggttt gaagtcttca tctgcaagat gctgcttgaa caattgtgct gctgcaaata
      781 cttttgtcag atctttttgt tctgcattca aaacagcttc gatgacatca tgacgaatat
      841 tcttcgttgt caataattgg cgcagacggc ctttgataaa gtcgatcacc tgttgttgcc
      901 cttctgataa accaatgccg aaacgatccg tatctttact gataacatca ctaatcgttt
      961 cttgcagaac agacaaagga aaggcccatt ttttcgattc gatgatccga acgacaccgt
     1021 atgcttggcg acgtaaggca taaggatcgt ttgacccgct tggaatcatc ccaactgcaa
     1081 agaaagaaaa aatgctatct aatttatctg caatcgctaa aacagaacct actgtagact
     1141 gaggtagctc tccttcactg gatataggca tgtaatgctc acgaatcgct gttgctacag
     1201 caggtttctc gcctttcagc agagcatatt tttcgcccat gatcccttgt agttcaggaa
     1261 attcccctac catgttggtt actagatcaa atttatagat ttcagcagct cgttgcagat
     1321 ccatcaattc ttcctcagat agtcctactt gttcgccaat gatacgggca atgacttgta
     1381 cccgctgcat tttctcatag atactaccga ttttttcatg gaaagtaaca gtttttagtt
     1441 tttcaacgta ttggtcgatt gaagctttct tgtcttcatt ataaaagaat tccgcatctt
     1501 ctaaacgagc cgtcaatact ttttgattgc ctcgaaccac attttccaat tttacccgat
     1561 caccattacg agcagaaata aaatgaggaa gcagcatacc ttgatcgttc cgtacctcga
     1621 aataacgttg atgttctttc atagaagtga ctagtacttc ttcaggaaca gaaagatatt
     1681 tttcttcgaa gtcgccagaa aagacagttg gatattcgac taaattgttg acttcttcta
     1741 gtaaatcttc gtctagatca ataacccagt gatttttttc ggctaattca tttgcttgtg
     1801 taacgatcat ttcttgtctt ttttgcggtg aagcaataac gaattgttca ttcaattttt
     1861 cttcatattc ttttgcatgc gcaaatgtca catcttcgcc taagaaacga tgtcctcgag
     1921 aggctctgcc tgttttgaca tctaagatct caaacgggat tacttcgtca tctaacaatg
     1981 ccacgatcca gtgaataggg cggatatatt caaaatcgta ttctgcccaa tgcatcgtta
     2041 ctgggaaagt gaggctttta atgacatctg ctaaacctgt caatacttct ttcgcttctt
     2101 tgccgtgagt gtatttcgtt acatagacat attccacgcc ttttaattct ctaaaagtga
     2161 tagcatctgt cgtcagacct tgtccgcgga caaatccttc agctgctttc gtccagtttc
     2221 catctgcgtc caaagcaatt tttttggctg gtcctttgac ttcttcttca ctgtctgctt
     2281 gacgttctgg aatgtttgtt actttgattg ctaagcggcg cggtgtagaa aacgtttcga
     2341 tcgtatcata agtcaattgg ttttcatcta aaaattttgc tgttttttct tctaattgtt
     2401 tcatgcttgg tgtgacaaca tgagcaggca tttcttccag cccgatttca agtaataagt
     2461 cttttgccat cttattcagc ctccttcatg ttttctggat ttgctgtgtt tttattcaat
     2521 aaagggaatc ctaatttttc gcgttctgcc acaaagattt tggctacagc acgagccatg
     2581 ttgcggatac gggaaagata acctgctcgt tctgttacgg atactgcacc gcgagcatct
     2641 aataaattga atgtatggct gcatttcaaa atataatcat acgctggatg aacaagattt
     2701 tcatcgatac agcgtttagc ttctttttca aaacggtcaa agttgcttag tagcaagtct
     2761 tggtcactta cttcaaaaga atatttggaa tgttcatatt ctggttgttt gaagatctcg
     2821 ccatatttca caccatcagc ccattccaga tcatagacac tttcaacttc ttgaatatat
     2881 gaagcaagac gttctagtcc ataagtgatc tcagaagtaa ctggtttaca aggtagtcct
     2941 ccgacttgct ggaagtacgt gaattgtgtg atctccatcc catcaagcca tacttcccaa
     3001 cccacaccgg cacaccccat cgatgggttc tcccagttgt cttcaacaaa acgaatatcg
     3061 tgttctaatg gatcaattcc taaaagacgc aagctttcta aataaagctc ttggatattt
     3121 tcaggtgaag gtttcattac gacttgaaat tgatgatgct gatacaaacg gtttgggttt
     3181 tctccataac gcccgtcagc tggtcggcgg gatggctcta cataagcagc attccatggt
     3241 tccggtccga ttgcccgtaa gaatgtatat gggctcatcg tacctgctcc tttttctgtg
     3301 tcataagctt gcatcagcat gcagccgttt gatgaccaaa atttttgtaa tgttaaaatc
     3361 atatcttgga cggtcaattt tttactcatc tgttttgccc ctttcaattt ttaagcgttg
     3421 ctgtcaataa gaatacagga aagaaaacga caaaaagtcc ctatgtctga ttacagacat
     3481 agggacgaat aatttcgcgg ttccacccta cttccgaata aagattcggc agcttcattt
     3541 atcgtactcg caagtgcctc ttcaaaaatc gtttgggtcc ggcttccact ctcccgaact
     3601 cgctaaacca cgtgtttttt actgatcttg gtcaatgtac gtattcattt tgcagttttc
     3661 ttgtttatat aatagatcct ctcagtgaac gatctattta atctacggtt aataatagac
     3721 ggaagtccct gtatttgtca aatagttttg atttttttgt tgtatctttc atttattctt
     3781 ctttttcagg tatctctttt tcaggcatat ttttctctgg cgtctttaat acgtgtgccc
     3841 aagacttcat ttgatcaatg aactttttgc tttttagatg aataccgaca tattcatcat
     3901 acaactggtc aatgaggtca cggattgcct gcttcgtttc ttctttcaag tggattccac
     3961 tgatcttatc ataagaaata gccgaaaaca ttcgaacgaa ataaacagcg cgaggatctg
     4021 catgataacg gtgttcgtcc attggccagt gtttctcgca tatcacaccg ccagatttgg
     4081 aagaatagtc aaattttcct tttgtttccc cgcatacgac acagtgcgtc caaattggcg
     4141 cgattccgaa gcgttgcagt atttgaactt caaagatatt cgtgatgatt tctgcatcat
     4201 ctccttgatc catccgctgc agagcttgtt gcgtaaattg gaataaatgc gggtcatatt
     4261 gatgatcttc gattgctgca tctactagat ttagcaaata ggtaccataa ccgctcaaaa
     4321 agatatcttc ttggatgttc cgaaacgcat ggacgtcttt gacactgctt aaaaacgaca
     4381 aaccttcact tcgaaaatta ccgatataga ctgcttcggt aaaggggagc aaagccggag
     4441 ctaatggctg attttgccga tggattcctt tgatataaaa catcattttg ccagaagatt
     4501 ccgtaaagat tttgactaat ttatcttttt ctttgtaatt acggctagat aaaatcaagc
     4561 ctttcgattc tgcaagctgg ctcatattct ccctcctaaa aaataaatct ggaaaagcag
     4621 attctgccga tccagattat ttatgtttcg atcttccgcc gtttttctca acgtgcggat
     4681 ttttatccag tttatttcta tacttaacct ataagaagtt cagaatatca gtattcgtct
     4741 tttcggtagc caaagtcttg cagatagact tttttgtctc gccagtcttt ttggactttg
     4801 acccaaagtt ctagaaatac tttgtctcct aaaagatttt cgatatcctt tcttgctttc
     4861 gttcctactt gcttcagcat ttttccgcct ttgccgataa tgattccttt ttggctatct
     4921 ctttcgacga tgatcgtggc ctggatatgg attttatcat tctcgtttcg cttcatcgaa
     4981 tcaacaacga ctgcgacaga atgaggcact tcgtctcgtg ttaaaaacaa gactttctca
     5041 cggatcaatt cagaaacgat aaagtattca ggatgatcag tcacttgatc atctggaaaa
     5101 tattgtgggc cctctggcat ttcactgact aatacatcca ttaagcgttc gacattgttt
     5161 ccttctgtag cagagatcgg aatcacttgt gcaaaaggca tctgcgtcga ataatcttcg
     5221 atgattccca gcaactcgtc tggatggatc ttatcgattt tattgataat cagataaact
     5281 ggagaatgca cgttttttag acgttcaata ataaaatcgt ctccccggcc gcgtttttga
     5341 tcagcactga tcataaataa gactgcatcc acttctttca acgcactgta agctgcttct
     5401 accataaaat ctcctagacg atgctttggt ttatggattc ctggtgtatc gataaaaatc
     5461 agctgagctt ctggtgtagt atatactcct tggattttat ttctagttgt ctgtgccttg
     5521 tcactcataa tggcaatttt ttgacccacg attcggttca ataatgtgga ttttcctaca
     5581 ttcgggcggc cgacgattgc gacaaaccct gatttatgtt ctggcatata cgttctcctt
     5641 tttaattaaa caacaaatga tatattttag ggacaaataa aatcaaccca atgatgacag
     5701 caaaacaagc ggtcactaaa actgctccag ctgccatatc tttgattttt ttcccaatcg
     5761 gatgaaaatg aaaatccgta aacatgtcca ctacattttc aaaaacagta ttgatgatct
     5821 ctactatcca aacgagaaaa acagctaaaa gcagccataa ccactctatc cgatcaagct
     5881 ggaaaatcac gcccataaat aaagcaagga taccgaacgc aacatgtttc ctcatattgc
     5941 gttcttcctc aaaaacggtt ttgactcctt ggacagcaaa ttccacagac atcaggaaat
     6001 gtttgttttt ctctacgttt ttatcttttg agtccatagg catccaagat ctctttctgt
     6061 aaaccaaaca tttctttctc atcttctggt gtcatatggt catacccgtt gatatgcaag
     6121 aatccatgta ccgctaaaaa gccaagttcc cgatcatatg aatggccgta agcttctgct
     6181 tgttcagcag cacgttcaat agaaatcatg atgtctccta gtacacgagg caaaggattc
     6241 tctccatctt caaaaatcac tgggatttcg tcttcgcctt cttcttccag agcaaaactg
     6301 atgacgtctg tcggtgcatc ttttccacgg taatcacgat tgattacttg gattgccgca
     6361 ttgtccatga aagtaacaga catttctgtt tcctctggca gctttaaata agatgctgca
     6421 aattgcagca agtcatcgat ttctttcatt ttctcttctg agacttggtt tgtttcatcc
     6481 ataaaggtaa tatccattat acatcgcttc tttctattct tcttgttctt cctttatctt
     6541 ctcaacttct gttttcattt taggatattt gatccgagaa tggaaggtgc tacttaaacc
     6601 gctgatcaat gatttttcca cttttcggat ttctttcaag gtcagtccac tatcgtctaa
     6661 ttgaccatcg gaaatacgct cttcgataag attatggaca aaactttcga ttttttcgct
     6721 cgtcggatga tccattgccc gtactgcagc ctcacaactg tcagcaatat tgacgatccc
     6781 tgcttcacga ctttgcggtt ttggtccagg ataacggaat tgctcttctg ttacttccgg
     6841 attgcgttct ttcgctttga tgtagaaata acgcattagc gtggttccat gatgctgttt
     6901 gcaaatatcg atcaccattt gcggcatatt ataatcttcc aatattttgg ctccatctgt
     6961 cacatgtcca aagataatat gtttactgtc ttctggcaat aagaaattgt gcgggttttc
     7021 cgctcctgaa ggcaagttct caacgaaaaa gctagcatgt ttgatcttgc cgatatcatg
     7081 ataatagcaa gctactcgag ttagcaaaga acgtccgccg atttctgcta cagcgttagc
     7141 acttagatta gctaccatca tactatgatg ataagtacct ggcgcttctt ccagcaactg
     7201 tttcaataaa ggatgatttg gattgctgag ttcatttaat acaattacac tgtcatcatt
     7261 gaccatcaat tcaatatatg ggtgtagacc gatcgtcagc aagaatgaga agagtgcacc
     7321 agtgaacccg cagacaagca ttaaccaagt cgttgcatca ccaaagctca ttccttgata
     7381 gacgatcaaa atgacatcca tcatcacagg aaaaataatg acccacatgg cagcagataa
     7441 tccttgttct gagatccgtt tgcgtctgac aatcgttgcc atgagcccag agaaaacata
     7501 agacatcaag ataatcgtta gaaagttcgt gccaatcgaa tcataaaaaa tgaaaagtgc
     7561 agatactgct tggaaaatac cagccatgat ccctgctctt cggttcaaga aaaagcttaa
     7621 aacaagtggt gcaaaagcag cgggataaaa cagcgggata taagtagctt gttccgtttg
     7681 gaataattgg aaaaatttca tcagcactat gctgactgac atagctgtca catagaaaag
     7741 cacgtatttt gttctttctc ctgcattttg gaattgaagt gaattataaa tcagtacgcc
     7801 gatttgaagc aaaacagcta aaaccatggc aatgagtggg aaaatcgaag tcgtttgatt
     7861 cgtcaatcct agtaattcca attttttcat cgctgaagca tcaatttgat ttccttcgcg
     7921 aacaatgatt tctccttgga agatcatcac tggttgtaca gcttctcgtg cagattgttt
     7981 taattcttct gtctttttct cattcaatac atcattgact acaatgcctt gatccactaa
     8041 gtagcgaatc atttgttgct gctctgttgt gacattcaaa tactgaatct gatcttctgc
     8101 ttcttgttta aaagcttcca attcgctttc acgaacttgt ttactcatct gttcgtcaat
     8161 gagcttcaaa ctttcatccc taaccgcgtg aatttccgtt tcagtcattt caaatatcgt
     8221 cgaataaaaa ttgttcggca gtttttggta aaacgcaacg ttttctgcat tcacgttttc
     8281 aaaatttttc ttcagtgtag caatccgctc ttctgtagta ggtttcggga tattttcatc
     8341 ttccttcgcc ttatctacct tgtcattata agatttgttg atggtatcat tcgtcttatc
     8401 gatcaattcg aataattgct tgatccgatt gttctggtca tctgccagat ctttttgata
     8461 agtatattct ggagtcactg cttctgctgc cagttttctt ctttgttcgg tttcttccgt
     8521 gttctcgatc gttttattcg cacggatact ctcttctgct acttggcctt ctctgaaatc
     8581 attggccttt tgtttgacac tactaaatgt aacgccgcag acaatgataa aaaacaagaa
     8641 cagaaggaaa ggcaatgctg cctttccgag tttttcttgt agtttctgca gtgttttatt
     8701 caacatgtgc ttatcctcct aagcaaagct tattcttgat gaagatccgc cttttcataa
     8761 gctttgatga tttcggcaac tacagggtgc cgaacaacgt cacttgcttc aaaattaaca
     8821 aaatcgattt ttttgatttg ctttagtgtt cgttctgcat gaacaagacc acttgtcgtc
     8881 cctcgaggca agtctatctg acttgtatcc ccattgacaa tcatttttga ttgataaccg
     8941 agacgggtca agaacatttt catctgagcg actgtcgtgt tttgtgcttc gtccaagata
     9001 acgaatgcat catccaatgt ccgcccccgc atgtaagcta atggtgcgat ttcgattacg
     9061 cctcgttcca tcaatcggtt cgtatgatcc aatccaaaaa tttggtataa agcatcataa
     9121 acaggccgca gataaggatc cactttttct ttcagatccc cgggtagaaa gcctaggttt
     9181 tcccctgcct ctacagcggg ccgcgtcaaa atgatttttt gcacttcgcc tttttttagg
     9241 gcagcaattg ctaatactac ggcaagaaac gttttccctg ttccggctgg ccctacacca
     9301 aatacgatgt catgtttggc taccgattca acgtatttct tttgaccgct gttttttacc
     9361 cgtataggtt ttccattacg gtctttgacg atctcttcct catacatctc aacaaaataa
     9421 tctaatgtac ctttttgccc cattttcaat gccgtcacga catctggtgt acttacgtgg
     9481 attcctcgtt tgatcaattc ctgtaatgtc cgaatgactg aggcagccaa ggaaatctgg
     9541 gattgttcac caatgatctg aatgatttct ccacgtgtat ggatggttgt ttccgttgtt
     9601 tcctcgatca gttttatatg cttgtcgtgt gcacctaaaa gcatgctgac atcatcagca
     9661 gctgtcaatc taatctctaa agaactagac tcttccgtca aaaatagaca tccccttttt
     9721 ttcgattcat tctttcctat tttaccatac tcagaagaaa ctatatagca aataagaaaa
     9781 ggttgtaaaa gagtcgttta accatacgta ccaagaaacg ttaaaaaata gctgtttcca
     9841 ttcgctaaag gtctcgtttt gataaaaaga atctgagaat gtaagttata tgaaagtgga
     9901 gaacaaaata ttccgtttca ttcagaggta ttctctaggt atttttcttg tttcaaaaaa
     9961 agaaaacaaa atagttaaaa tattcttgca tttcaaaaaa aacaggtgta ttattacgtc
    10021 aacaaataaa catacagcaa agcgtcgagg aaaacagtag gctattcaac gatttattcc
    10081 cagtgagtca tgtaagtgag aaatgacaat aaatcgaata gacgaacatc atttccgagt
    10141 caatgtcgaa aacgtagatc attgtggctg cctccattat caggctagcg gataacttta
    10201 tcaaaaagcg tccgtgaatg aagaagcttt tttaagcgaa aaaaggtggt accgttctag
    10261 aatctagagc ccttttccca agtggaaaag ggcttttttt tatattttaa ggtggtggtt
    10321 ttcatggaat ctgatattag tggcattact aattgctgca acgtttatat cgtcaatcaa
    10381 aatgataatt attggaggaa aaatttatgg aagaaacaaa aacttattca tggaaacaac
    10441 tattgatggt cagttcactt atcttcggga tgtttttcgg gtcaggtaat ctaatctttc
    10501 ctgtccactt aggtcaaatg gctggcgcaa actgggtcag tgctggcgta ggatttgcca
    10561 tctcaggcgc tcttttccca ttactagcta tcttagctgt agtagtgaca aaaagtgatg
    10621 gtctgtatga cttagctaaa cctgtcggaa aatggtatgc tgccttgttc ttaatccttg
    10681 ttcatttgac gatcggacca tttttcggta caccacggac agctgctact gcttttgaaa
    10741 tggctgctaa accatttttg cctgaaaaat ataattcatt aggtatgttt ttattctctg
    10801 ctcttttctt tttacttgct tatttcctta ctgtccatcc cacacggttg gtcaaatacg
    10861 tcggaaagta tctaaactcc ttgtttcttg cattattagc aatcattttt gtcgtttctt
    10921 tattccaccc aatgggaaat ctaaatcaat ctgctgcaga tacttaccaa acaaacgctt
    10981 taacaaatgg tgtcctagaa ggttataaca cggttgatgc agtagccttg cttgccttaa
    11041 gtgtcacttt tgtccatgca gtccgtgacc ttggtttcaa agataaaaaa gtcacagaat
    11101 taacagcaaa agctggtagc ctgagcgttg cgctagaagt catgatctat tttggtcttg
    11161 ttcttctcgg tgcgatgagt ttgaataaga tgtctttatc agaaaatggc ggaactgcac
    11221 tttctcagat cactaatttt tatttaggta acttcggcgc tagcttctta ggagtgatgg
    11281 tcacattagg tgtcttcact accgctatgg gactcgttgt ttcttttgca caagatttcc
    11341 ataaactgtt ccctaaagtc agttatatga catggctgcg gttaacgact ttcgtctctt
    11401 ttgtcgttgc aaatgctggt ttggacaata tcatccaatg gtctttacca gtattgatgc
    11461 ttttgtatcc attgtcgctt gcgttgattt tgctttcctt aacagcaaaa tttttccaaa
    11521 agacaccatt tgtctatcaa gtaacgatgt tgtttgctgc tgttcccgcc gtattggata
    11581 tgctggcaaa ttcgcctgct ttagtgagtc aacaaagagt tgtagcaagc atgctcgaat
    11641 tttatcatca tcacgttcct tttgctgcat tgggacttgg ctggatggtc ccaacgttac
    11701 ttgggtatgc tggcagctta ctcttctatt acgcctatcg cctatcaggg tataaacaag
    11761 aagcaaatga actaccagaa gaataaccag atcaaacaca atttaacata agaaatatta
    11821 aacaggaaaa aaacagctag atgaaagaat cctattcttt cgtctagcta ttttttagat
    11881 ctctttttta cgagcacaaa aaaactgcgg acaatgattg tccgcagttt aaatgataaa
    11941 attaagattg taatagttct ttcacaatgg catttacttg gtttccatct gcttttcctt
    12001 tgactttagg catgatcgca cccatgactt tgccaaattc tttcattgat gaagcaccag
    12061 tttgcgtgat tgcttcttga acaagttgtc gaatttcttc gtcggaaagt tgttccggca
    12121 tgtatttttc gactatcaca atttcacttt ttactttttc agctaaatcg tcacgtcctg
    12181 cttcttcaaa ctcatgcaaa gaatcacgtc gctgtttcat ttcgcgagac aacaccgtta
    12241 attcttcttc ttctgtcaag tcgtgacctt ctttaatctg ctcgttttgt atagatgact
    12301 tgatcattcg gatgacttgt aaagattcct tatctttcgc tttcatcgct gttttcatgt
    12361 catcgtttaa tctacttagt agtgacacac taccaactcc aattcatcac agaactagaa
    12421 ttttttgcgt tttctagctg cttcagattt tttcttgcgt cttacacttg gtttttcgta
    12481 gaattcacgt ttacgagatt cttgtaaagt acccgctttt gacacggaac gtttgaagcg
    12541 acgaagagca tcgtcaagtg attcgttttt gcgaacgact gtttttgaca tgttaattcc
    12601 ctccctccga gcttaaaaag taaccgtaat tgttattgaa atatatctca aaaaacaaga
    12661 ctgtcctgta aatattatat ctaatgctgt tttgaccgtc aaggaaatct tgcttttttt
    12721 taaaattatc aaatgttatt ttatttaaat ccttattgac aattttcaca tcttccgaaa
    12781 atctcgaatc tatgcccttc gatcgtacat ccaccgagct gttcttcgaa ataattcatt
    12841 ggacacatat ggatttcttt cgttgttccg cacaccgtac agataaagtg atggtgatgg
    12901 ccgatttccc cttgacagca atgaaaacga aacttcatct ctccatttaa atcggtttct
    12961 tccagtaaat cgatttctgc aaaatcatgg agatttcgat aaatcgtatc gtaacttact
    13021 cctttgaatt cctgattcat atagtcaaaa acttctttag cggatacgta gcgattgcgc
    13081 ttcactaaat aagttaacaa tgcttctctt tttttagtat atttaaaacc gttatttttc
    13141 aatgtttcta gtgattgttc gatcaacgtc tgttttttca tgacttattc ctccaaatca
    13201 aaatgattac gaagtacaca ttctagagta tggtataata aacataaaaa aaatgcaagt
    13261 gaggttttat ccatgtcttc cgattctaca gaaatcgtta ctttttttgt catctccgac
    13321 tctgctggag aaactgcgac aaaactagcg caagccacta tggcccaata tcctagcgtt
    13381 gagttcaatt tattccgcag aacatttgtg acagatgaga aaacattgat gcaggcactg
    13441 caagatgcac tagaagaaaa agctcttgtc ctgcacacat tgatcaatca agaattgatc
    13501 gagatgacgc gttctttttg tgaagaacat caattattta gttttgatgt gatgactccg
    13561 ccgatatcag aaatcgagcg cttaactggt atcaagccca ttcggcaacc tggcgccctt
    13621 catttattga atgagaacta tttcaaacgg atcaaagcaa tggaatttgc tgtaaaatac
    13681 gatgacggga aagatcctcg tgggtttcta gaagcagatg tcgttttgct aggcgtatcc
    13741 cgaacttcca aaacgccttt gagcttgttt ttagctaaca aaaatttaaa agttgccaat
    13801 ctacctttga tcccacaagc acatattccc aaacagcttt gggagatcga tcctaaaaaa
    13861 atcgtgggac tgacgaataa cccagatatt ttaaacaata tccgtaaaga acggatgcgc
    13921 tcttacggat taaatcctga tactgcttat tccgatatcg aaaaaatacg agctgaactc
    13981 gattttgcga atgatcttta tgaaaaattg ggctgcgtag taatcaatgt cgcttcttta
    14041 tctattgaag aaacagcttc gcttattttg aatgctttag acctagaaga ccatagttat
    14101 tatggaactg aaaccaccga agaaacagac taacaatttt tctttaaaaa aactggactg
    14161 tgtcagcgaa gaagattcgt tgacacagtc cagtttgtct ctatttgcac ctatcgttat
    14221 tgatgttcca catgtttgag tgtctggttc aaaatatcca gtacgtgaga atcatcaaga
    14281 ctatacaaaa tcgcttttcc ctcacgatgg gacttgacga catggttttc tcttaataaa
    14341 cgcagttgat gcgatacagc agattgttcc atttccactg cttggatgat tgctgtcaca
    14401 ttttgttccc cgtctttcag atacagcaga attttgagac gagtggggtc actcaacatt
    14461 ttgaatagtt ggctgacttt ctctactttt gttttttgcg tgtctggcaa tccattcacc
    14521 tccaacttga aaaaagactg acttctaaag tttaccactt tttccatcag tctcaagttt
    14581 ttttattctt ctgtcatctt ttggataatc gtttcataag cggctacttt ttcagctgcg
    14641 tcttctgaag agtttccttt tacaccgata taaaatttga ttttcggctc agttcctgaa
    14701 ggacggatag cgatccagcc attttcttcc agcgtatact tcaatacgtc agatggcggt
    14761 gtcgttagtt tttctacgtt tccttcacgg tctgttctcg tcaactcttt gaagtcttct
    14821 gtttggatga cttttgctcc ggcaaattct gttggtgctt cttcacggaa tttttccatc
    14881 aaagcagaga ttttcgcaga accttcttgt ccgctcattg tcacagaaat cgttttttct
    14941 gcgtagtagc cataggtttc aaaaatcgtt tgcaagccat catacaacgt tttgccttgt
    15001 tttttatagt aagctgctac ttctgctaat aagagcaatg cttggatcgc gtctttgtcg
    15061 cgaacgaaag gtttaactaa ataaccgtaa ctttcttcga atccgaacat aaaagtatgg
    15121 gaatgatctt cttcaaattg ttgaattttt tcagcaatga atttgaatcc tgtcaataca
    15181 ttgaacatgg tagccccata gtgttccgca attgctgtag gtaattcgct agaaacgatc
    15241 gatttcaata ccgctgcgtt ttcaggtaaa gtgcctcgcg attggtgtgc ttccaaaata
    15301 tattgagcaa acagtgctcc gatttggttt ccggtcaata cttcatagga gccatttggc
    15361 aaacgaacgg ctgcacctaa acggtctgca tcaggatctg ttgcaatcag caaatcagcg
    15421 ccttctttct cgccaagtcg tatcgcatac tcaaaagcag agtgttcttc tggatttggt
    15481 gatttgactg tagtgaaatc tgggtctgcg acagcttgtt ctggaactag tacgaattgt
    15541 tcgaatccag cttgtttcaa cgcacgttcg cccaacattt ttcctgttcc gtgaagtggt
    15601 gtgtacacaa gtttcaaatc tttccccatt gtttccacca attcatgatc aatcgttact
    15661 gctttgattt cttctagata agcggcatcc acttcttctc cgatgatcgt gatcaatccg
    15721 ctatgttcag cttcttcgtc agataatact tcaactttta acggattgct gacttcacgg
    15781 acatatttcg tcaatgcatc tgcgtctgca ggaggcattt gtcccccatc ttctccgtag
    15841 actttatatc cgttgtaagc tgctggattg tgggatgcgg ttaccatgat tcccgcaaac
    15901 gtcttcaaat gacggactgc aaaagaaagc tctggtgttg gacgtagact ttcgaataca
    15961 taagatggga tattgtgatg tgctaatgtt ttggctgctt ccatggcaaa ttctggtgat
    16021 tgatggcgtg agtcataagc gatagcgaca cctcggcgtt ttgtttcttc gccttgtgta
    16081 tccatgaaac gtgcaagtcc ttctgttgct tgtcttaccg tatagatgtt cattcgattg
    16141 atcccaggcc ctaagattcc ccgcatgcct gcagtaccga attccaacgg tgcataaaaa
    16201 gcatcttcaa gtttttcagg atcttcaccc agatcattta attgtttttt taagttttct
    16261 tctaaatttt cttcatgtac ccattgttca tacacttgtt cccaagacat gaaaataaca
    16321 cctctttctg aaatatggtt cttaataagt atagcattca cttattagat atgaaagtat
    16381 gaggaccaaa aaacgcttaa atcaagaaag gattctttta tcaagcacgg ttgcaagtat
    16441 tcgcataaat cggattcagt agatttcacg cgaaaaaaaa gagtaaaaga acaattaaac
    16501 cgttcttcca ctctttttaa acttatgcag ttgtttcttc taaagattcc aagtatttat
    16561 acacttgttg tccagcgatc ccaccatcac caacagcagt agtgatttgt cgcaaatctt
    16621 tttcacgaac atctccgatg gcaaaaacgc ctggtatatt cgtcttcatt tcgttgtctg
    16681 ttggaatcca gccagcttcg ttcgtcaacc ctgcttctct aaatggtgca gttaatggat
    16741 ccagtccaac atagatgaat actccgtctg ctgccaaatc aaactcattg ccggttttga
    16801 cattacgtgc tttcacacct gtcactacca tttcattccc aacgatttcg tcaacgactg
    16861 tatcccacat aaaggaaatt ttttcattcg caaatgcacg gtcttggatg atcttttgtg
    16921 cacgtaattc atctctacgg tggacgatga ctacttcaga agcaaattgt gtcaaataga
    16981 tggcttcttc tactgctgag tctcctcctc cgatcactac tagacgtttg ttacggaaaa
    17041 acgcaccatc acaaactgca cagtaagaaa cgccacgtcc agcaaattct tcctcgccag
    17101 gtacgcctaa tttacggtgg atacagcctg ttgcgataat gactgttttt ccttcgtaag
    17161 ttttatcttc acaaataact tctttgtggc tgccgtgatc cttgatatct tgcacgattc
    17221 cataagcatt ttctgtccca aatcttgaaa caccttcata catcttataa gctagatcag
    17281 gacccattat tgaatcgaaa ccaggatagt tttcgatttc tgccgtattg ttcatttggc
    17341 cgccaggggc gccttgttcg atcatcaata cggataagtt tgaacgtgaa gcatataaag
    17401 cagcagtcat cccagcagga cctgcgccaa taacgattac atcatacata tgtagattct
    17461 cctttactta atcaagtaag catactttac agccaatgcg aaaaaaagtc tattgttctg
    17521 cttgcgtttc tcgaatagct ttattatact cgaaaaatcc gctgaaaaac aatagacttt
    17581 tataaatcat tgatcaatca ttcgaaagat tttctccatt tgaatcaatt acttttttat
    17641 accagttgaa tgatttcttc ttcgaacggg ctaatgtgcc atttccttcg ttgtcacgat
    17701 cgacataaat gaatccgtac cttttcttca tctcacctgt accagctgat actaaatcaa
    17761 tacatcccca agtcgtatag cctaatagat cgactccatc taattctact gcatctttca
    17821 ttgcctggat atgtgctgcc agatagtcga ttcgatagtc atcttccaca taaccattct
    17881 catcgggcgt atcgactgca cctaagccgt tttctacaat aaatagtggt ttttgataac
    17941 gatcataaat atcattcatc gttattctca agcctaatgg atcaatttgc caaccccatt
    18001 cacttgcttc cagatatgga tttttgacag aagcaaagat atttcctgca gtctgttcca
    18061 agagttcgtt gtcagtagtc gaaactcgag aagaataata agaaaaggag ataaaatcaa
    18121 cagtatgttc tttcagcaat gcggcatccc caggttccat tttgatctga atgccatttc
    18181 gttccatttc tttcaatgca taagcaggat attctcctcg tgactggaca tcaatgaaga
    18241 aataattttc tcgatctgat tttctagaag cccaaacatc ttcaggattg caagtgtatg
    18301 gataatatgc tcctgctgcc agcatacagc ctactttgtt ctccggatct acttcatgag
    18361 caatcttcgt tgcgatggca cttgcaacca actcatgatg tgccgcttga tatttgattt
    18421 gttcttcatt ttctccttct tcaaaataca gccctgcgcc catgaatggt gcatgaagga
    18481 tcatattgat ctcattgaat gtcaaccaat atttgacaag tcctttatag cgattgaaga
    18541 tgactcggca cagattttca taaaaaccaa cgagttctct ggaacgccac gcaccatatt
    18601 ctttgatcaa atgcatcgga caatcaaaat gtgtaatcgt cacaagcggc tcgatcccgt
    18661 acttttgaca ttctttaaag acatcctcat aaaatttcaa accagattca tttggctctt
    18721 tttcatcgcc cattggaaaa atacgactcc aagcaatgga catccgataa gtcttgaacc
    18781 ccatttctgc aaataaagca atatcttcct tataatgatg atacatatcg atcgcaattt
    18841 ttgctggata aaaatgattt tcatcaaatt caaacatttt cttttttcca gtaatgacag
    18901 gaaaacggtc ttctccgatt ggcacaacat ctacgttcgc taacccacgt ccgccttcat
    18961 cataaccgcc ctcgcattga ttggctgctg tagctccgcc ccataaaaaa tcttttctga
    19021 atcccatcat acttcctcca ttacatgtgt attgcttgat aattctcttg ccagttcatc
    19081 ttggacttcg attccttctg cttttaaccg gctgattgtt tccttgaatt gcggtaaata
    19141 ctgctgatgt gcaataaaca actcattcat gatccgtttt gctgtctttc ctgatcgtat
    19201 aagcggattg atcgtaaacg cttgtaaagc tgttccataa tcaccagtca cagctgcttc
    19261 gatcgtcagc aattccatat tcttcattac ttgcaaccag cctctttcag cagcaggaag
    19321 ggaaccaaac gctacatttc gtgcgccttg tgcgccaaca taggcagtga cttctactac
    19381 acaatctgcc ggcagatcag gaacagctcc atcattcttt gtagatacca cgatctgtgt
    19441 ttctttattt ccatagatcg aagcaatcgt ttcacaggca gcatctgaat aataagcacc
    19501 acctcgtttt tgcaattgtt caggtttatg atccaattct ggatctttgt ataattcaaa
    19561 cagctctgct tctgtttctt tcacttgctg cgctcttgta ccaatcgttt gatattcttc
    19621 taaagcatgt tccagcattt cttcttcacg gtagtaatag cggtggtagc cacaagggat
    19681 catgttcatt tgttttaatt gttctttgaa aaacgggata tcaaagatat ttttcggcaa
    19741 tccattgtct tcatcgtata aacgatcaat caattctgcc gtgcggtcat ttcctttatt
    19801 atctgctact ttgtgccaat ggaagtgatt tagaccggca aacttgtaga tcagctcttc
    19861 ttttttcttg ccaagcattg ttggttctgt catcatcgcc attactggca cattgcataa
    19921 tcctatcact ttatcccatt tgccatatct gataactgct tctgtcacca tcccgcttgg
    19981 gttcgcgaaa ttgatcagcc aagcatttgg acataaacgc ttcatgtctt caacgattgc
    20041 caaaaccact ggaacggtac gaaaagcttt gaatatcccg ccagcaccat ttgtttcttg
    20101 cccaatcatc ccataataac tagggatccg ctcgtctttg attcgtgcat ctaattgacc
    20161 gacacgaaac tgagtcgtaa caaaatccgc atctttcaat gcttcttccc gatccagagt
    20221 tgcatagatt ttgacttcat acggagaagc atcccacata cgctgagaca tctgactgac
    20281 gatctcaagc ttttcttttc cttcttctac atctacgagc cagatttctc gtatcggtaa
    20341 ttcctcatat cttttgataa atccttccat caactcgggg gtgtaactgc tgcctccacc
    20401 aatcgtagcg attttgattc cttttgccat gttctcactc ctttactttt tacactttta
    20461 ttatcttttt tgtaaacaaa acaaacaata gaaattcgtt tctttccagt aacatttaca
    20521 aaagttagtg ttttctactg gatttttgta aatatcttgt caaaaaatgt ctttattaag
    20581 ctatataaca taaatccgtt tacaaatcat tttcaaaaaa gttataattt acgtaaaaaa
    20641 acaagaagaa ggtatctaca tgttattacg tgaaaaaatc aaagaaatct ccttttctcc
    20701 ttcagaaaat gaagtgattc agtttctctt aagcgattct ccagcacttg gcgaaatgac
    20761 catccaagag attgctgagc gatgttatgt ccacccgtcc acactcatcc gtgtagcaaa
    20821 aaaaatgggt tttgatggct gggtcagttt tcgtaatgct tttttagctg aaacagccta
    20881 tcttgaaggg aattttcaag acgtagatgc gaatcttcct ttttccacca cagacggtat
    20941 tatgacgatc gcaaataaaa tggcttcttt agaacagatg acgattcaag atacactttc
    21001 tctcattcat catgaccaac tgcaaaaagc caaacaacta atgcttcaag caaaaaaaat
    21061 cgtgattttc gccagtaact cgaatacttt gatttctcaa gatttcatgc tgaaaatgaa
    21121 gcgcatcaaa atggatgtca cgattgtcac cacttttggt gaatcgttct atgaagcgta
    21181 caattgcacg agtgatatgt gcgggattct gatttcttat acgggtgaaa acaatgtgat
    21241 ccttcgtacc gcagaaatat tgaaacaaaa tcatgttcca attttagctt tgaccagtat
    21301 cggtgattca acgctatctt caatgagtac agccgctttg cgacttacga cacgcgaacg
    21361 actgtattcg aaaattggta attttacgat caatacatcg atttgttatc ttctagacgt
    21421 gttatatagt tgtgtttttg cagaaaatta tcaacagaat ttagtccatc taatttctgt
    21481 aggacaaaaa tttgataaac gccctatcag ctcagccatc atgaaagagc ctttcaattt
    21541 tgaaaataaa gaagtggact aaaaagaata attaagccta gtccattctt tcacctaacc
    21601 gttcaggtca gtgcggtgat aagtgcatcg tctggcccga ccgtctcccc ttgattttcc
    21661 aaaatatcca aataatccgt gtaattggtg acgatcacag gtgtttctaa actgtatcct
    21721 tcctcttcga ttttcttttt gtcgaagcgg agcaacagat cgccttgttt cactctttct
    21781 ccttgctgca ccaagctttc aaaatatttc ccttccaact gaacagtatc caatccgaca
    21841 tgaatcagca attccagacc tgcttcagaa accattccga ttgcatgttt cgtcgggaac
    21901 agggtcatga ctgttccgtc aaaaggggca cgtacttctc ctttttcagg gtagatcaag
    21961 attcctcgac ctagtgttcc ttgtgcaaaa gctgcatcct ttgctgcatt cagtggagcg
    22021 atttgtcctt gtatcggtgt ttttacaatt tctttacctg atcttttctg tctatcatct
    22081 gtttcacctg cttcctcctt ccaaaagaaa aaagtcagcg caaaggatac caccatcgca
    22141 atggcgattc caatcaatac attaatcaca tccgttaaat caccatctgg tctaatatag
    22201 ttgggaattg taaagatgcc taatccacct ggattccaag aagttaaatt cattaatcca
    22261 ctatacgcgc cccctaacgc accaccgaca caggtaaaaa taaatatttt tttacgtggc
    22321 aatgtaaacc cataaatagc tggctctgta atccccacaa taccagaaac aatggctggt
    22381 attgcgattg ctttgtcttt tgggtttcta agcttaaagt agagtgcagt aagtgctgca
    22441 gtttgtccaa aagacactac tgcaacaggt gtcatgatat tttgccaacc attcacagaa
    22501 aattgcatca atcccattgg tacgattgcc caatggagac caaacatcac tagaatttgc
    22561 cagaagaagc ctacgattgc tccataaata actggcgaaa gtgctaaaag tgtttcaaat
    22621 ccagccatta aaatatcagt tgcgaatgtg aatgctggtc caacgagtaa aaaacctaag
    22681 ggcattgtaa taagaacggt gaagaatgga acgaagaaat tcgcgatcat ctcaggtact
    22741 aactttttaa ttggtttctg aatttggcta gctaacaaca caataaagat aatgggaatg
    22801 acagaagaag cgtagttacg cgcaatccag ggaatgccga atactgtttg ataaataggt
    22861 gcttcaaaaa tagtgccaga aaatatggta gtcagtggtg cttctgctgc accactcaaa
    22921 gcttccagcg acaagctagg attcattaat gctgccccaa gcaacatccc tacgaattca
    22981 tttactttaa atttacgggc agctgttaaa ccgataataa caggcataaa ttggaataca
    23041 gaatcaccga tattatcaaa cataacaaat gtgccagaac cgcggtcaaa tgcgcctaag
    23101 aagacaagta atgctgtcag tccacgaatc atcccaccag cagctagaat agcaaggaat
    23161 ggctggaaac agcccgatat tccatcaata agcatatcaa acggtctcat tttttctgtt
    23221 gaaacagcct catcaaaagt aaggtttcct gcttttataa cctcttcaaa cacgactggc
    23281 acatgattcc cgatgacaac ttggtactgt cctcccgctc gcattaccgt cacaacaccg
    23341 tccatatttt tcaagatctc atcatttgct ttttcttcgt tttttaattt gaaacgaagc
    23401 cttgtgatac aatgtgtcaa accattgata ttttccttcc cgccgacatt ttctacaatt
    23461 ttgctcgcta attcttgata ttttcccatt tctattccct ccaatttatt agtggaaggt
    23521 ttagccaact gaatgtcact acccttattt catgcgttct tgttaattta tcctcctttt
    23581 tttatttatt tacaacgatt ctcatgcact aaacgcgcaa tatggatcgt taaatacatt
    23641 ttttcgtccg tggacatctg gtagttgaat atctcggcta aaaagtctgc tattttctca
    23701 acgcaaccaa acgtatcctt atattttttt tgaataacct ggtacaattc ctcagaaact
    23761 tctcccactt ctgatttttc tccatctagg acgcgtgtca gaaaaaaacg taggtgtgtg
    23821 acgaatcgaa aaaaatggac tgaatcttca tcaaatgtaa tcttatagta atagcggacg
    23881 atatttagaa tatcctgtat tgttgtagta aacaggtagg tattgtcttg ttggctttga
    23941 atgccttgtg cattgactaa atgcaatgcg ataaatccgg cttcatcttc tgataacttg
    24001 atgtggtatt tatccgagat tttcttcact gtttttttcc cgatggcata ctctttagga
    24061 aatagttgtt tgatatcata cagcaataca tttggtacaa atattcccat tttgtgacgt
    24121 tcgatagccg tatacaaatg atccgtcaat gcaatataca ccgaatcatt caactggact
    24181 tgtagagcct cttttgtata ttcaatgatt tcacaagaaa tttctaagta ctcaagagga
    24241 atcgcttgtg ccaattcttg gaactgttgt gaaagtccgt catttgtcaa ctgaaatttt
    24301 ttgtcgatgc atgagtcaaa aatcgggtca cccactttct ttttgaatgc caaacctttt
    24361 cccatcacga tcatttcctg atttctttca tccctggtta ttacgacgtt gttattcagt
    24421 actttctcaa tcagcatgtt ttactccttt ccatgatata tagggctgta tccaaaacaa
    24481 aaagaaaaac ccaaaaagcc gtccatggaa ccatgggaga ctcatcaggt ttagcttgca
    24541 tcaggcaatc actatccaag ttgtatcgtt ttctttatat tatcgaaagc aagcactttt
    24601 gtcaacgctt tcttagcggc tattgggcac ttctgactag ctgtcgtgat tttttttaaa
    24661 tctggtaatt acgacactaa cgctcacaga tgaagaatct gggaagctct gttttatttt
    24721 cactctagcg cttaggtcaa aatgctacta tgctactgtc ccaacttcta atatacggtg
    24781 ttccagtacc agcttatcgg tgataagcca aatttatgca aaaatctgga aagccttttt
    24841 tacaattttt ttcttatcac ctaaagctga acggagccct gtcacaacca ctttttacac
    24901 accactgctt tgcagtttgt acatatctgc atacaaacca ttttgcgcta gaagtgtttc
    24961 atgattccca cgttctacta tatgaccttt gtctaaaact aaaatcaatt ctgcatcccg
    25021 aatcgtggac agccgatggg caatcgcaat cgttgtccgt ccttgtcgca tttttgtcaa
    25081 tccttcttgg atcaatcctt ctgtttcagt atcgatattt gctgtcgctt catccaatac
    25141 tagtatttta ggatctgtca cgattgttcg cgcaaaagtg atcagctgtc gttgtccgct
    25201 agaatagctg gcaccgtgtt cgatcacttt tgagtgatat ccttttggta attcatcgat
    25261 gaacttgttt gcttgaacaa actcagctgc atggcgaatc tgttcgtctg tgatagttgg
    25321 attcatcatc cggatatttc ctgcgatatc tccataaaac aagaaggcat cttgcaagac
    25381 caatcccatt ttcttacgta actcttccat tggatattct cgaatgtcat gatcatcaat
    25441 caagatctgg ccttcataaa attcgtaaaa ccgcatcaat acgttgatga tcgagctttt
    25501 tccgcttccg gtgtgcccca ctaatgcaac ggtctctccc ggattagcga caaaagagat
    25561 attgttcaat acattgtgct ctccatcata agaaaagctt acattgcgaa actcgatctt
    25621 acctgaagta atcgcttgat ctgctccagg attttgttgc ggtgcatatt cttctgtatc
    25681 catgattttc aaaatacgac taccggcaac cattccatct gtaaaggtgc tcaaaaagtc
    25741 catcatttga gacattggat taaaaaatcc ctggacatag gtcgtaaatg catagatcag
    25801 tccaacttct acgggagaat gcagcgcatc gatcccaaac aaagtcaacg ccaacgcaat
    25861 cgccaatgca tatagaaaat tgatgatcgg acttaacaga atcgaatttg ttttgatcat
    25921 cgcatagcgc gtgtctaaat actcgttgtt cacttgttca aattctttag ctaaacgagc
    25981 ttcttggcga aactgctgga taatacgcat gccggaaatc gattcattca atttcgtgtt
    26041 cagctgactt aatttttccc gcatattccg gtaaatacga gaactgaatt tctggtaata
    26101 ccagatgacg attcctaaaa tcggcaagaa caccaaagtc cacaaggcaa tttctccatt
    26161 gatttgaaac atggcaatga aggaagaaac gactgcaaag atcccagtca ataccatcaa
    26221 aaagacatac caaaattcaa atagcgtttc tgtgtcattt gtcactcgag aaacagtcga
    26281 tcctgccggt gtctgatcaa aataacgcat acctagtgta tgcagctttt caaataatct
    26341 tacccgaaca tactgatagg tcttcaatga agccatggaa tacaaatacc attggaaaaa
    26401 ccaaatgata cttttgacta tgactccaaa caagtacata ccagcaaaaa acaaaataac
    26461 ttgtgtcgta gccgactgtt tagccagatg atcatccata aaagtttgga tgatccttgg
    26521 caataggaca ttgatcacag acagggcaaa cgcaaataag atagcaacga tgaacgttct
    26581 tctaaaaggt ttggcgaact tcatcagtcg tttgatgatc ttcttctgtt ctttaagtgg
    26641 aatcgatttt gtccattccg attgataatt ttcatccatc aggcctcgcc tccttctatc
    26701 ttcgcttcta atttctgttt ctcccacatt cgttcatacc agccgcctaa tgcaagcagc
    26761 tcatgatggg ttcctcgttc aatgattttc ccttgatcga caacaatgat ttcttttgca
    26821 tgcatcacgc tgcttaaacg gtgagctgca atgatggttg ttttctcttt tcttatttct
    26881 tttaaattat gcaagatagc ttcttctgtt ttggcatcta ctgcagaaag tgcatcatct
    26941 aagatcagca attcaggatt tttgatcaat gctcgagcaa tcgaaatcct ttgtttctgt
    27001 ccgccagata aagagactcc acgttctcca actaaggtat cataaccttt tggtaattcc
    27061 ttgatttcat tgttgataaa tgctaaagaa gccgcatgct ctacttcttc ttctgaaagt
    27121 tttggattag aaaaacggat attatctcga atggtcatcg aaaacaagaa gtgatcttga
    27181 ggcacatagc cgattgatcc taataaagca ttcaatgaat attctttgat cgaacatccg
    27241 ccaaattgaa tttttccttg ataatcatcg tattcacgca tcagtaattt gatgattgtc
    27301 gtttttcccg caccagtttt cccaacaata cctaatgttt ctccttcttg gatcgcaaat
    27361 ttgatttgtt ctaatgctgg tgattcttct ttcggatagt taaaagagga aatagctaca
    27421 ttcagctcgc cttttgccgg agtctgcact gcacccagtt gttccacgat atgcgtcttt
    27481 tcatgcaaaa gttcattgac gcgatcataa gaagcatttc ctctttccaa tacgttgaac
    27541 aatcgaccaa tcgcaaacat cggccaaaca agcataccga tatagctaat aaatgagacc
    27601 atctgcccga ttgagatcgt gccttccaag acatactttc cacctaaaat aattgttgca
    27661 acataagaca gaccgataat caaggtaatg aatggatcaa ataaggagtc taaaaaattg
    27721 actcgtttgt ttttaataat tgcatcttca atcttttctt caaaatccgc gagatcttct
    27781 ttttcttgtc caaatgtttt aatgactttg atcccagtaa tactttcttg tgtcttatca
    27841 ttgatactag aaaaagcttc ttgcgaatca cgaaaagcat cgtggagttt tgaccccagc
    27901 actcgtgaag taacggctag taaaggcaga ggaatcagcg caatcagtgt taagcgccaa
    27961 tcaataaaca aaatcatcgc aatgatcgtt gttccgcccg tgatcactga atctgcaaag
    28021 gtcaagatac cagctcctgc tacattttgg attgcattca aatcattcgt tgcatgagcc
    28081 atcaaatctc cagtccgata tttttggtaa aagagattgt ccatttctgt aaaatgtttg
    28141 aatagctgct gccgaagttc tttctccaac cgagctgcac ttccccaaat attcgtccgc
    28201 cagatataac gaaaaagata ttgtaagaga gctgcaagga tcaataataa gatccaccag
    28261 gaaatgatct ttattgataa atttttatcg gcgatctcat caatgatgat cccaatcact
    28321 tttggaggag ctaactgtac caaggccact gcgaataggg agaaaatccc aattaaataa
    28381 tgtttctttt cctgtcgaaa aaaccaacct aattttctaa aaatcgacat tttactcctc
    28441 ctttgtcttt atcaagagca taggattgtc tgtgcttgtc ttttttgctg aatagtctga
    28501 atagtctaac aaattacgaa ataaaaaacg gactgaaaaa atcagcccgc aaaaagtctt
    28561 tgggtcagaa cctatttttt cccttggttc ttcatttgct gcatcatctg gcgaattttc
    28621 ttctcagatg gtttttgccc cattgacatc atcattgatc gcaacatgtc ctcattaacg
    28681 ggaggatttt tttctaaata gtctttcata tatttacgcg ctaggaaaaa gccacctact
    28741 gcgccgatta gcaaagcaat aatagcaata agtacgacaa tacctgttga taccatataa
    28801 atctctcctt tctatttccg aattgctctc aatgatttat tttactaaag tttattgaaa
    28861 aaagaaaggc gtattcttta gtttcatgca aaaaatagtg gtttttttag agaagaacaa
    28921 aatttctttc attaaccagc aagacacgcc acgaaaaaaa attaggcata ccaaatcttt
    28981 ttctttaatt ttttctttct gaggtgtaga atgtaatcgt agataaatag gaaaggtggt
    29041 tttttcttga ataatcaatc caacaaacaa tttcataagc atcgacttat tgaacataca
    29101 aatggtttat ctttagctga agtaaatgga acagtggatg tacccaaggg aaaaagtttt
    29161 tttaaaacac ttcttgctta ctctggacca ggtgcattag tagcagttgg ttatatggat
    29221 ccaggtaact ggtccacttc gatcactggt ggacaaaatt tccaatattt attgatgtca
    29281 gttattttga tgtctagtct gattgctatg cttttacaat atatggcagc aaaattagga
    29341 atcgtgaccc aaatggattt ggcccaagca atccgagcac ggacaagtaa gacattgggt
    29401 gtcattttat ggatcttgac tgaattagcc attatggcaa cagacatcgc agaagtcatt
    29461 ggtgcagcaa tcgccctcta cctgcttttt gatattccat tggtaattgc cgtatttatc
    29521 actgtgttag atgttttcgt ccttttattg ctgacaaaag tcgggtttcg taaaatcgaa
    29581 gctttggttg tctgcttgat tttcgtcatt ttattcgttt tcgtctatca agttggcttg
    29641 tctaaccctg attggcacag tttgtttgcc ggatttatcc ctaacagtca cacattctca
    29701 gactcaccgg tcatcggcgg cgaaactccg ctgactggag ctttagggat tattggtgca
    29761 acagtcatgc cgcataactt atatcttcat tcagcagttt ctcaaactcg gaagatcgat
    29821 caccaagacg aagaagatgt agcacaagcg gtacgctttt ctacttggga ttctaatatc
    29881 cagttgtcaa tggcttttct agtcaatgca ctgctattga tcatgggtgt ggctgtattc
    29941 aaaaccggtt ctgtccaaga tccttccttt tttggtctgt atgaagcttt atctgatcca
    30001 tcagctatga gcaatggtat cttgattgct gtagcaaaat ctggtatctt gtctacttta
    30061 tttgctgtag cacttcttgc ttctggccag aactctacta ttactggtac gttgaccggt
    30121 caagtcatca tggaaggctt catccatatg cgtatcccaa tttggctaag aagactagtc
    30181 acacgattgc tttctgtgat tcctgtattg atttgtgttt tgtttacaag tacaaaagga
    30241 acgatcgaag aacataccgc tttgaataac ttgatgaatg aatcccaagt ttttctggct
    30301 tttgcattgc cattctcgat gattccttta ctgatgatga ccaatagcca agcggagatg
    30361 gggagccgat tcaaaaattc atttgttgta aaactacttg gctggttctc tgtgattagt
    30421 ctgacttact tgaatttacg aggattacca ggtcaaatcg aaagtttctt cggcgagcaa
    30481 gccacctcag ctcaactagc attggctgat caaatcgctt atgtaatcat tgttcttgtc
    30541 cttctcctgt tggcatggac gattggtgat ttatataaag gaaacaaaaa atatgaacag
    30601 cgtttgcagg aaacgataga agaaatcgag tagaaactga ttcttttaca caaaggaggt
    30661 tgtgtcagaa gtgggcagct tcaagaaata agaaggaatt taagaaaatt gcttttcaaa
    30721 tttttgtgaa atttcggctt atttccgaag aagttacttc tggaacaccg tgtatcagag
    30781 gttgtgaaaa agctgccttg catcaagtaa taagaacagc caagtaaaaa cagcttttta
    30841 tgtttttaac ttggttggac ttattaccgc agatgcaagc ttttgagcac cgtttattcg
    30901 gaaaaaggaa ctgcgacaag acttttgtca cagttccctt tcctacgatt agtcaagtaa
    30961 aaggtgtaag aaaaatagct cataaacgaa agcgacaaaa tcaa
//
LOCUS       DACBYO010000028        30202 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.028, whole genome shotgun sequence.
ACCESSION   DACBYO010000028 DACBYO010000000
VERSION     DACBYO010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.028"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(38..1189)
                     /locus_tag="IVD26_001212"
     CDS             complement(38..1189)
                     /locus_tag="IVD26_001212"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAP6079200.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="IVD26_001213"
     CDS             complement(1202..1639)
                     /locus_tag="IVD26_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6079201.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="IVD26_001214"
     CDS             complement(1654..3420)
                     /locus_tag="IVD26_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAP6079202.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="IVD26_001215"
     CDS             3684..4361
                     /locus_tag="IVD26_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079203.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="IVD26_001216"
     CDS             4364..5491
                     /locus_tag="IVD26_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079204.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="IVD26_001217"
     CDS             complement(5691..6131)
                     /locus_tag="IVD26_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6079205.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="IVD26_001218"
     CDS             complement(6142..8175)
                     /locus_tag="IVD26_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP6079206.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9880)
                     /locus_tag="IVD26_001219"
     CDS             complement(8177..9880)
                     /locus_tag="IVD26_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6079207.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9974..10924)
                     /gene="manA"
                     /locus_tag="IVD26_001220"
     CDS             complement(9974..10924)
                     /gene="manA"
                     /locus_tag="IVD26_001220"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAP6079208.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10963..11988)
                     /locus_tag="IVD26_001221"
     CDS             complement(10963..11988)
                     /locus_tag="IVD26_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAP6079209.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12197..13066)
                     /locus_tag="IVD26_001222"
     CDS             complement(12197..13066)
                     /locus_tag="IVD26_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAP6079210.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13525..15417)
                     /locus_tag="IVD26_001223"
     CDS             complement(13525..15417)
                     /locus_tag="IVD26_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079211.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15414..17141)
                     /locus_tag="IVD26_001224"
     CDS             complement(15414..17141)
                     /locus_tag="IVD26_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079212.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17157..17807)
                     /locus_tag="IVD26_001225"
     CDS             complement(17157..17807)
                     /locus_tag="IVD26_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6079213.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18011..18307
                     /locus_tag="IVD26_001226"
     CDS             18011..18307
                     /locus_tag="IVD26_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP6079214.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18479..19099
                     /locus_tag="IVD26_001227"
     CDS             18479..19099
                     /locus_tag="IVD26_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAP6079215.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19191..20357)
                     /locus_tag="IVD26_001228"
     CDS             complement(19191..20357)
                     /locus_tag="IVD26_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP6079216.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20369..20722)
                     /locus_tag="IVD26_001229"
     CDS             complement(20369..20722)
                     /locus_tag="IVD26_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAP6079217.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20850..21872
                     /locus_tag="IVD26_001230"
     CDS             20850..21872
                     /locus_tag="IVD26_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAP6079218.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(22311..22745)
                     /locus_tag="IVD26_001231"
     CDS             complement(22311..22745)
                     /locus_tag="IVD26_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079219.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22855..24714)
                     /locus_tag="IVD26_001232"
     CDS             complement(22855..24714)
                     /locus_tag="IVD26_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP6079220.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(24832..25992)
                     /locus_tag="IVD26_001233"
     CDS             complement(24832..25992)
                     /locus_tag="IVD26_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAP6079221.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26299..27210)
                     /locus_tag="IVD26_001234"
                     /pseudo
     CDS             complement(26299..27210)
                     /locus_tag="IVD26_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
     gene            complement(27376..28569)
                     /locus_tag="IVD26_001235"
     CDS             complement(27376..28569)
                     /locus_tag="IVD26_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6079222.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(28653..28856)
                     /locus_tag="IVD26_001236"
     CDS             complement(28653..28856)
                     /locus_tag="IVD26_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAP6079223.1"
                     /translation="MMNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVI
                     MNGNRIQIKRKQFEKIIDTLDTI"
     gene            29113..29355
                     /locus_tag="IVD26_001237"
     CDS             29113..29355
                     /locus_tag="IVD26_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079224.1"
                     /translation="MAHQPSGSAQTECVRMPYDAPPLSCGHIYQGAIRPPGKHRNGER
                     VSRFMLPGPVRQFVTIAWMSLISRRRFMASSRHTCG"
     gene            complement(29277..29510)
                     /locus_tag="IVD26_001238"
     CDS             complement(29277..29510)
                     /locus_tag="IVD26_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6079225.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(29517..29948)
                     /locus_tag="IVD26_001239"
     CDS             complement(29517..29948)
                     /locus_tag="IVD26_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP6079226.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         8479 a         6440 c         5483 g         9800 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgca ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac ccaggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcaa
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgact gtttgtgaga
     9241 attcgattcc taaaggtgtc aatacaccat gattgattgc attattgaaa aatagtactt
     9301 ttagaggttc taagatcaga ctgacaagtg gtaacagatt cattgtgact agccaagaca
     9361 caacggaggc gagcaacaag tgaacactat ttaaaactgg ttcaataaaa acgattccaa
     9421 ttatacaaat aacgctacca gtcagtccta ctagtaggtt gctgacaagc atttcatatc
     9481 cagccttgaa tttcacgtgg aatctagaaa caaattgttc atatacgatg ccggcaagcg
     9541 gcccgataat catcgctcct acgatttgtg gagcattgga acgagcgatc aaccctaaag
     9601 aagcaattgc accggcgact gccccttttt gtccccctac cgatttcccg cctgaataac
     9661 tgatcaagat gggtaaaagc agctggatca tccaatggca tacctcttct aatgtggtgt
     9721 gcaaatcgcc agacacacct tttgttgcta atgacaagat tccccaagcg ataaacagac
     9781 ttagatttgg catgatcatt tcatttaagt gatgtccagc ttttctcagt tgtttcatag
     9841 acacgcgact gctgttgttt gctttccatt tgtattccat ctttttcacc atacttctat
     9901 ttattgatgg acggatttta tgtagaaaaa gcagcaaacg aaaaaccgtc tgctgctttc
     9961 agctatctgg gaactatttg cctggttcag tcgcaatgat tgctagttca ccttggaccg
    10021 cccactcaga aacgccattt ggaataatac agcttgttcc tttttctaat ggatatgttt
    10081 ttccgtcaac gacaaggtct cctgctcctt cgattaccgt catcaatgta taaggggctt
    10141 gttttttgaa agatgtgatt cctttaatat cccactcata tacattgaaa aactcagttt
    10201 ctaaataagt gacgatcgat gaattccctt ttcggacttc tttgatttgt aattctggtg
    10261 ttttcgcagg gacagttgtt acatcgatcg attgttggat atgcagctct cttgtttgtc
    10321 cttgcgcatc ttttctgtcg tagtcataca cgcggtaagt cgtgtcagaa ctttgctgtg
    10381 tttctaaaat catgattcct ttaccaatag catggatcgt tccgcttggt acataaaaga
    10441 aatcaccttt tttaactggt actttcttca aaaggtcatc ccagcgccca tctttgatca
    10501 tctcagctag ttcttctctt gtctttgcat gatgaccata gatgatttct gcaccaggtt
    10561 cagcatcgat gatataccag cattcagttt ttcctaattc accttcatgt ttcatcccat
    10621 aggcatcatc tggatgtact tgtacagata gatcatcttc tgcgtctaag atcttgatca
    10681 ataatggaaa cactggttct gaaggatggc caaacaattc cttgtgttct gaccatagtt
    10741 catctaatct tttccctttg aattcgccat tttctactac actgacacca tgaggatgcg
    10801 cactgatcgc ccaatcttct ccgattttat cgttagggat atcaaaacca aagactgaac
    10861 gtaaacgact tcctccccaa attttttctt gaaaaactgg ttttaaaaac ataggttcct
    10921 gcataattca aactcctctc atttttcata gctattatag cattatttcg gtaataccgc
    10981 tttctctttc aaaaagtttt caacaatttc atctcgacat atgagatact ccgcacgatg
    11041 atcgacagga tgtacgcgat ttgacaaaaa tatcaacgct tcttgtgttt ttatatcaat
    11101 caagaaaaac gtacctgtat aaccagtatg aaaaagaatc gcatgaccgt cttctacatc
    11161 cttttttaag tcccatccta aagaacgata gccatttttt ttcggtgttt gatcttgcag
    11221 taaagaatca atcgtctctt cttctaaaaa acgaccatta cggatttttc ccttgttcaa
    11281 atacatttgg acaaaagtaa tgctgtcttt caaatcaata aagagacccg cgttacctgc
    11341 atgttcagcc aaaactcttg ctttcggatc atgagtttgt ccacgcaaaa cctcacccga
    11401 aggcagttgt tctgtgggaa cgattttttt ggaaggaaaa ggaagaaata agctgttcat
    11461 cattcctaat ggttccaata cttgttcttg aaagatttcc actgcagttt cttggtaaat
    11521 ttcctctagc atcaacccaa gaagaatcgt accggcatct gtatatttta cttcttttcc
    11581 tagttgctca cctggttcta gcttcaaata agcggcgatc aattcttcct gagatagctt
    11641 atctctgttt ggtatccatg ttttgatatc agaagtatgt gtcagtaaat gacgcaaagt
    11701 gattgtctga ttttcaaatt caggaagata tttatgaagc ggttgatcga gttctatctt
    11761 tccatcttct aatagacgta aaactaatga agtggttgca acgactttcg tcagtgaggc
    11821 tgcatcaaac aacagatctt ctgtcatcag ctgcttttca ggaacgactt gggcaaagcc
    11881 ggctgtaaat gtttctactt gattttcttt tatgaaggcg actgctacac ctggataaaa
    11941 tccttcttcc atctttttca aaataagctg tttcgtgtgt ggatacatct ttttctcctg
    12001 cttttctatc agattcttac agtccaagct taaagcttaa tctatgagga atcaaccttt
    12061 tttacacaaa aaaactgcgc gaaaaaccgc gcagtttccc ccggtatact attttctctt
    12121 tctatctcta gaataagcga tagtatgacc gttcataaaa tgacgagaca tgcgacaatc
    12181 gttaagaaag aaaaagttaa gcgtcgcatc gaatgtcagt tttattcttt tcttttggct
    12241 cactgacgaa ccaccattcg attcctatag catcatagat tgtgagtact gtgtgctttt
    12301 tgtctaagaa gaaatcaact gatagttgct gcaagtgagc aatcagtcct tccatgcttt
    12361 cagtatcgat catgaatttc agaaaatcaa gtccaatcac ttcatctgta ggcaaatcaa
    12421 ttgcgcctcc gctagcttct gtcaaaccaa catggaaatc tccttcattc aatacatgga
    12481 tgccctcttc ttcattatgt accttcaaac caagtacatg attaagaaat tggcgttctt
    12541 ttgttaagtt agtaacattt aaatggattt tttcaaaata agaacctgtt gatagtttac
    12601 tgaatttttc ttcagatttt cttaataatg cttcttgatc cattgtttct ggaatttctc
    12661 tttggtcgtt cttattctct tcatggtaaa tttccaattc attctcttct gggtctacga
    12721 gcaaaatccc catacgtcca tgatcttcta aagcttcttt gattggataa ttcattttac
    12781 ggatacgaca aaggatatct gccatttctt ctgtgctagg gataatcaat gaaaaacggt
    12841 tcagcttttt gatcaccccc atgtgatcat tcgctctagg actttcttcc agcagcaaca
    12901 tttcacttcc agcttcttct gttcctaaaa tggctaattc gttttcttct cttttcaaat
    12961 caaagccaac aacgttcttg taaaaatcaa tcattttatc tcggtctttc acccgaatgg
    13021 ctacactttt taaataggtg gcagccccca attgaaaatc tttcatattt cttgctcccc
    13081 tctacgtcaa gctttatttt aacgatggat tcttcttctt tcaagcaata actttgattt
    13141 tgttaaaaaa aatgtgagaa aattcgcatt ttgcttgttt tttgtaaatt aatgagtaaa
    13201 aactcttata aaaagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    13261 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    13321 tgaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagatac
    13381 aaaacggaaa aatagcttct catattttgc cgttttttga gctaataccg aaggacagct
    13441 gattgaacac cgtttattcg gaaaaaggga ctgtgacacg acttttgtca cagcccctaa
    13501 aaaaaataat aaatttgtac tattctatga agcttcttct tcagaaaact gactgttata
    13561 aagatctgca tagaatccgt ctttttccat caatgtatcg tggtttcctg tttctacgat
    13621 cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt attgtagaca agcggtgagc
    13681 aacaacgaaa cttgtccggt tttccaatag gcggttcatc gctttttgaa tcagtatttc
    13741 tgttcgtgta tctacactag atgttgcttc atcaaggatc aggacatctg gatttgctaa
    13801 gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc gaaatattgc ttgcatcctc
    13861 gtttaataca gtgttatatc cttctggcaa tttacgaaca aaatcgtcta cgtgagcagc
    13921 tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg ttcccatatt tgatattgtc
    13981 atagatactt cctgtaaaca gccaagtatc ttgcagtacc attgaaaact gtgcgcgcaa
    14041 ttcatcacgt gaaagatcac gggtatctac accatcgtaa cgaatactac ctccagaaac
    14101 atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc cctgcaccag tcggacctac
    14161 aatagcgacc atctcaccag gtttgacatc caagttaaaa tcagtcatta gcaagttatc
    14221 tggtgtgtag ccgaattgaa cattttcaaa acgaactttg tatggtgtat ctttttcttc
    14281 tggaaggcca gatttttcat tggacatctc ttcttcatcc aacacttcaa atacccgttc
    14341 ggctgaagca actgttgatt ggatagtgtt catcaaactt gcaagttgag tgattggttg
    14401 agagaactgt gttgtatatt gcaagaacgc ttgaacatcc cctaatgtca tgttcccatt
    14461 tgcaactttt actccgccta gtacagcgac gaacacatag cctagatttt taacgaaatt
    14521 catcaacggc atgatgattg ccgaaataaa ttgagctttc caaccagcgg catacagatt
    14581 ctgattttct ttttcaaata cttcctggtc tttttcagta tgattgaatg ttttaacaat
    14641 ggtatgacca ccatatgttt cttctacttg gttattcaat aaacctaaac ttttttgctg
    14701 atctgcgaaa aacacttgtg atttcggcgc tacgatcatc acgatgatca agcttaaagg
    14761 gatcatcaat aacgcgacta acgtcaattg ccagctgatt gaaagcatca tcacgatgac
    14821 cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa ttttgctgca gcgtgcttgc
    14881 gatgttatcc atatcattga ttgctcgaga catgatatcc ccatttgtat gtgtatcata
    14941 ataggaaatc ggtacacgat tcattttggc ttccaaatca tgacgtaatt cataaactgt
    15001 tcgttgggaa acacgtgtca taataaattg ctgtaaaaag ttgaatacag cagaaatcaa
    15061 atacatcacg attactgtcg caatgatctg cgcgatttta tcaaagtcta tcggaaattt
    15121 tgttacttgt tggccttgtt gcatctgttg agcgccagcc attacacctt tgaatatttc
    15181 tgtggttgct ttccccaaga cctttggtgt ttggatttgg aagatcacgg ctgctattgc
    15241 tagtacaaat acagcgatga tcgcaaccat acgtttagac atatagccaa acaatcggcg
    15301 taccgttccc cagaaatttt taggcttttc accttttaca ccgagatttc tgccaggtcc
    15361 accatgtcct ggaccgcctg ctggtccatg agagggacgt gtgtttgttt tactcatgct
    15421 aagtcctcct ctcttagttg tgaatgaacg atttcttgat aagtttcgtt tgttgctaat
    15481 agttcttcat gtgttccttt gccaaccagt tttccttcat ctagcacaag gatcatatct
    15541 gcatccatta ctgtacttac tcgttgagca actaaaacgg tgatactttc tttcatattc
    15601 gttttcaatg cttggcgaag attggcatcc gttttgaaat ccaacgctga gaaggaatca
    15661 tcaaacacat agatatctgc tgttttgact aatgcccgtg caattgccag acgctgtctt
    15721 tgtccaccag agaagtttcc tcctccttgt tccacatggc tatctaagcc atcttccatc
    15781 tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt tccaaatcat ttcatctgtt
    15841 gcatccggct taccatactg catattgtct cggatcgttc cagagaacag aactgctttt
    15901 tgaggaacaa agcccattaa ttctcgcaaa ttatattgag tcatgtcact aatgtccgtt
    15961 ccatttattt ggatcgaacc agattcgatg tcatataatc gagggatcaa attgactaag
    16021 gtcgttttac ctgaaccagt cccccctatg attgcgacga tctcgcccga cttggcttgg
    16081 aaatcaatat cttccaatgc aagtttttct gctccatgat atcgataatt gacatgattg
    16141 aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt taggattttc agggtcatgg
    16201 ataccgattt tttcatccaa cacttcatta atacggtcag ctgaagcttg tgcacgaggc
    16261 accatgataa aaatagcgga aagcatcata aagctgatca agatctgcat cgcataagtc
    16321 ataaatgcaa tcagattacc gacttccaaa gtcatatctg ctatgtagtg tccaccaaac
    16381 caagtgattg ctacgtttgt accgctcatg atcaatgtca tcattggcat catcaatgcg
    16441 acgatcgtat taactttgat tgccgtattt gtataatctt tattcgctaa atcaaaacga
    16501 ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc tgacccctgt caatccttct
    16561 cgaaatacca ggtttaaacg gtcagttttc ttttgcatac ttttgaataa tggaacagca
    16621 aagtacatga ttccgccgat caaaataatc attactggga tgacaactaa gaagattttt
    16681 gtcaactgat gatctttttg ataagcaagt atgctcgcgc caatcaacgt gattggtgca
    16741 ttgatcatca tacgtaaaaa catttgtgta accatttgga tttgagtcac atcattggtc
    16801 gttcttgtga tcaaagaggc cgttccatat ttatcaaacg catcttttgt cagactctct
    16861 gattttttat agacatccgt acgcaattgc ttacccagtt tctgtgattc acgagtagca
    16921 aaaaatgtat ttgcgatagc agctaagata ctgatcaaag aaaagccgat catcacaaaa
    16981 cctgtatgcc aaatataatc gacatctcct tgcgctaccc ctttatcaat aatattggag
    17041 gtaagtgtcg gcaaatataa atctgccagt acttggatca ccatgaaaac tgcagctgca
    17101 attgctgaag tcaaggagat ccgttttacg atttttagca tctagttccc ttctttctat
    17161 ttatatactc cgtttttcag ccaagaaagt ttcaaattga attcactgat tgcttgctct
    17221 actgagtaat cttcagatgt tgaaaataag cgatacgaat gcgcaattgt tgtaaataca
    17281 gtattcatca ctaattggat cagtaattcc aattcatgat cattttttac tttcagcttc
    17341 gtccgatcga tcaattcaag caactctttt gcatcttgtt tgtgttcttt atgtggatcg
    17401 tgaggcgttt tttggcgact cgtatgagga gcgacttttc ttgaggcacg gtaatccatg
    17461 ttcataaaca agttacgata aaaagaagca ttctcgcctt ccaaaatctc ataaatcatt
    17521 ttagaaaaat aggattcgaa tcctttgaat agatcaccat cggattcttt cattagttgt
    17581 aacatatctt tagagctgtc acgtctcatt gtctcaaagt aataaaaata aagatcctct
    17641 ttatcttcaa aatactgata gaaactgcct ctagggatat ccgctaattt gacgatatta
    17701 gcaatcgaag cttcttttaa gggtactcta gaaaactcga ttctcgcagc ctcgattagt
    17761 cttttttgtt tttctttagg caaatggaaa aatgtctgtg tcggcatatg gatcctcctt
    17821 tctttcaaga tgacacattg tcatatgacg ctgtgtcatt ataacacctc ctacctgttt
    17881 tgcaagacat ttgcatagtt tttttcatta tcatccgata cattaaaaaa gtgataagag
    17941 gaatccttcc atttgaatta atgagagttg cccattaaaa tagccacata ctaaacaaag
    18001 gatgagataa atggcccaat caattagtgt ccaagacttc aataaattgc ctctcgatgc
    18061 tgacagcatc gttttagata caagaaatac cttagattac acaaaaaacc acttaagcca
    18121 ctcgctttct atccccgctg ctatcttgcc aagacaatta aaaaatctag atccaaagaa
    18181 actttattat attctaagct atacaggcag gcgatcagaa gcattagccg atcaacttac
    18241 tgctaatggt tttcgtgctg tttatatcat tggtgggatg gaagctcttc agtcgagtgt
    18301 tgcttgaata ttgcttgtta gattcaaaag aggctgtgac aaaaaatcgt gtcacagcct
    18361 cttttatacc ctgtcttttt ttagttattt attcttcaac cttatcaata tgacttgata
    18421 gccttttctt tttctcatag ttataacaat catagcaata aaaggagaag gtaagcatat
    18481 ggcatctgtt ttagtagtca aaggtcatcc cctaactgca gaagaatcgc gcacagttaa
    18541 ggcattgacg tcttttttaa caagttataa agaaaatcat ccagatgatg aagtgactgt
    18601 tttggaactt tatcgcgatg atattccgga aatcgatgaa gaattattat caggttggga
    18661 agcattacgt gctggtgcag aattcacttc cttatcagaa agtcaacaac aaaaaattgc
    18721 tcgtttcaat gaattgactg atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc
    18781 cttatggaat ctaaatatcc caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc
    18841 tggaaaaacg ttccgctata cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc
    18901 actgcacatc caatctaatg gcggtgtata caacggacaa gactttgcct ctcaatatgt
    18961 aaaaggtatt ttaaactttg taggcatcga tcaagtagat cagctattca tcgaaggaat
    19021 cgattatgac cctgaccgtg cagatgagtt gatgcaaaat gcattagata aagctgctgc
    19081 tttaggtaaa tcattttaaa aattgagata aatgcataca aaagagacag aggaaaaaat
    19141 cttcaaagca gcatttgtac cttggatatt ttcccatctg tctctttttg ttattctttc
    19201 tgctttttca acggattttc ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca
    19261 tgagtaatca ctactttagc tgctgcataa acaggaatcc ccaagatcac accgatgatt
    19321 ccgaacaatt tcccagaagt cagcagaact aataaaatcg ttactggatg gattgctaac
    19381 tgattcccta gtactaatgg agagatcaag cgtccttcta ttgtctgctc tactgcaaaa
    19441 acgatcagta ctttgatgat catgaatgga cctgctacaa tggctaaaaa gatagccgga
    19501 atcatcgcta aaaatgatcc taagtaaggg atcaggttca aaaaacccgc aataatcccc
    19561 aacgtgacag catactctaa accaatgacc gcaaaaccaa tcataaacat gattgccaca
    19621 gcaaaagcca cagttagttg tcctcttata taagaagaaa cttgactatt catttcactc
    19681 agcacattca acgtcggttt ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct
    19741 aattgtttac cgtctttcaa tagataaaat aagataaacg gcatcgtcag cagagccact
    19801 aaaatagtcg ctaccgcgcc gacaaaactt ccaagactct gaactgtact cttagatata
    19861 tcttggatca tatcgcctgc cgaattcatg aacttatcac ctgctgtttc caactgttcg
    19921 cgaaattggt tgaacagcgg gtcccgcaaa atctcggtta atttattatc aatcgtatct
    19981 acatattgag ggaagttact gatgaagctc actgtttgtt cctgaatctt agggatgatc
    20041 actacgctcc cccatgcgat tagtgcaaca accaaaacaa acagcccaat gatactgtaa
    20101 agccttggta cttttcgctt ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag
    20161 attcctgcta aaatgatagg cagacctacg attgctaaaa attgccagat tggtgcaaac
    20221 aaatatgaaa cttttgtaaa taaaaagacg atcagcaata ttaacaatac aacaagtaag
    20281 gctgtgacta cttgattatt taaaaaccag cgccaaaacc acgataccgg tctgttcttc
    20341 ttattttttc cttccataat tcctcctgtt agttataaaa aatttggctt cccaaaccaa
    20401 tagcaggcag tctatgcgga tgaagataga ttccatttgc aatttgtcct tcttctggac
    20461 aagcatcaaa aatcaatgat acgtgagcta ctgtctctaa attcccattg gccatcggac
    20521 cgacataatc gatcgtatat acctgatcat caaaagcaat tgttccgcct gctttcaaag
    20581 aaaaaggttc gtcttttgat acttcttgaa tcaccgaata ttttcgtaag gcagctgttg
    20641 ctgttttatc gaacaaaatc agcatgggtt cttccttgtt tattgcttct gtcccaattt
    20701 ctgtaatctt tgcctgaatc attgcactct ctcctttaat tgctttcaaa aacagtataa
    20761 cacattctca ttctttagcc gtgtggaata attatgtgat agaataaaaa cgaaaactat
    20821 ttcattacaa ttaggaggaa tcagctcata tgatcgaaaa gataatttta ggaacctata
    20881 cgcgtcgcga aagtaaagga atctatacga tcgaccttga tacagaaaaa gaagaattag
    20941 ccaacctttc attagctgtt gaagaaaata gccctaccta tgtagcaaaa agtaaagctg
    21001 gcaatcttta cacagttact agtgtggatg gattaggtgg tgccggtgcg tacgataagg
    21061 attttcattt tttgaatgcg gtaacagagt ctggcgctcc tttgtgttat gtagcggttg
    21121 atgaagcacg tcaattacta tacggggcga actatcataa aggtgaagta aatgtctacc
    21181 atatattagg agatggcgaa ctgaaagcag cagattcaat attccatcaa gaagcgacag
    21241 gtcctcataa aaaccaagat catgcgcatg tccactatac ggatctgact cctgaccaac
    21301 gattagtcgt atgtgatctt ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg
    21361 gcaaattgaa tcttgtaact accttcactg cagagccagg aacaggccct cgccatcttg
    21421 tctttcatcc aaatggacaa ttcgcttatt tatttggtga attagacagc acagtccgcg
    21481 tgctttctta taataaagaa acaggtgctt ttgaagaatt acagaaaata tcgaccttgc
    21541 cagaagaatt cgacggtgaa aatggagggg cagctatccg catttcaaat gatggcaagt
    21601 tcctttatgc ttctaaccga ggacataact cgattgctgt attcgcagtt tttgaagatg
    21661 gttcccacat tcaaaacaag caaatcatct caacagaagg ggattttccc cgcgatttcg
    21721 cactagatcc aagcaataat tttgtcgtgt gtgccaatca gaacaccgat aatctgacat
    21781 tatatcgccg tcatcctgaa acaggattac tggaattact gaaaaaagat gtctatgtac
    21841 cagaatgtgt ctgtgtttat tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc
    21901 aagacgtatt agacagacta cgggaagaac taaatattcc tttctttgat gggaaaatcg
    21961 aagataaaga gtatagcgaa gaggaatatc agaaactcaa agccgattta cagaactact
    22021 ttgaacaata tgtacagaat gtagaaaact aatcagcttt ccatactatc tgaaaagaac
    22081 atcaggacaa gacttttccg tctatcctga tgttcttttc tacaaataaa aaaccgccga
    22141 gatggttaga ctcgacggaa aaggagtatt tactcgattt tgagtaagta caaggttgtt
    22201 gttggttata ggtatgtcat tatcataaag gattttgatc actctatcat aaaggtaata
    22261 ttacatttat attagataac tctagttttt attgttatca aagatttctt ttattttttc
    22321 aacaacaaat tagtcatttt ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt
    22381 tttgcttcag atgtattgaa tagatcttca tctacccctg attcaagatc gatactttgg
    22441 atcatttctt cacagcctgc tacatatgaa agataagctt tttcaaaatt tttatgaatg
    22501 cccattgctt ttgctggtgg acgcaaagta ctgactttct taagcattgc ccgatatttt
    22561 tttgttcctt cttcaaataa caggatgatc tcttcaagag tcgatttgtc cagttcactt
    22621 gtttttcctt catcaattgc gtttctgatc acttcatatt tcggatgcat tccttctccg
    22681 attgcttctg tttccttgac gatttgatcg atggactgca cataatagcc aatattcggt
    22741 aacatgttcg ttttcctact ttctccattg ttgttattat ttattctact tgtttttatc
    22801 ctcaaatgac aagtacttga aaaaatttaa tggtttctat acagctcgcc attcttattc
    22861 gtgctcaaag aaaccatctg ctaaactata ttgtttccct gcgacaatgt catattggat
    22921 caattgatat tcgtcgtaaa tctcttgttg cgagcgattg aattgcgctt ctttatacca
    22981 ctgtccgttt tgatagtaca gttctcgttc aaacgccgga agttcctgtt ctaatgataa
    23041 aagcagctga taaaagccat ttgttgtctg attcgtctgt tccattagat tcgctgcaaa
    23101 ataaaacgga ctggtgattg catcgtgagt cgtttgcttt tctaattctc ctttactgtc
    23161 gaacataaga aattgtgttt catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc
    23221 tgaatagatc cctggaagat gatcccccca aaaaacaact aaagtccttc tagaaagatt
    23281 cttcaattct tccgtgaact gcttcagtgc cgtgctgcta taggaaatat cttgcagata
    23341 attctctaag tcaagtgtcc cacttccatc tgaagttttt gcaggatagt ctagattatc
    23401 atactttcca tcgtagggca tatgtgtctg catcgtgact aaatgaatga actgaggtgt
    23461 tttttcttcc ttgagaagtg tcattacttc tttgtaagct gactcatcag aaatatatgg
    23521 attattctct atcgtatccg tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc
    23581 taatgtctga taaacatcct ctcttttata catcgaagta ttgtatggat ggatcgctgt
    23641 cgtctggtat gattgtgcgt ttaacgctga aacgatagaa ggaagctgat ccatttttgg
    23701 tacaagcatc gtgtaagggg tggtgagttg cgcattaaat aacgccatag aaaaaccagt
    23761 caatgcttca aattcgatat ttgctgttcc accgccatag ttttgagaaa gcatattgcc
    23821 actatatgtt tgatcagcta cttcataata atctgccaat ggctcaccag atacttctac
    23881 gccgtttaat cgactaggat ctgagaaact ttcactcatc acgaacacga tgttcggcga
    23941 ctcttcctct acagttttat ttttttcatc ggctagcttc tggtattttt cagtgatttc
    24001 tttgatcttt tctttcgaat atccttcagg ttcatccatt ggttctacct tcagattgta
    24061 caaaaaccca ccgataaaac cagtgttata gtagttcatt ttctggctgt aaggtatcca
    24121 tagtgccgtt ttattatatg cttttcgcaa caaattatcg ggattgttga aattactgat
    24181 ataccctagc agtccaattg ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct
    24241 tccttttttc aggcttcgaa acatgtacca gcaaaacaat cctatcacgg ttcctgcggc
    24301 agctaagatc actgtaaaca gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt
    24361 gatcatcttc aaatcgtctg gataaatcgg ttcttgccga taactcattt tcatataatt
    24421 tgcaaaacct aatacaccga tggctacgac atacgtaagg gaacctaaag ggacagatcc
    24481 tgctagtgca atcagaaaaa taagaataat cagcaagacg agacaggcta agaagaattt
    24541 ttccgtatgc caagaaaaag caaatttcaa cgcaaggtct acggatagat cattttgaca
    24601 ccactgcaaa aataaattac taaaaacaac aagaaaaaag atactgatga ttgctgctgt
    24661 tccttttaaa atctttttct gtttggtcga aagtctgctt atatatcttt tcaaatgctt
    24721 gctccttcat ttctatcaat aaaagaatgt tgcttctctt attttagttg tacgaaattc
    24781 gaaagtaaag aacggaaaga agaattaatg aaatccaaat attctctttc tttatggcct
    24841 ttctggtttc tttaataagc ggacctttcg tactccagaa attttttcta gctgttgttt
    24901 cacttgattg agctgttcaa aatcagtact gtctatgtca atcaatatgt agacatgctc
    24961 attcttatgg ttacgcgata tatctgcgat cgctagctcg ttctcattca gcagagaaaa
    25021 tatctctgct aatatattgg ttttcttttg ataaaatata gtgaatcgaa acggcgcttg
    25081 gaaaaacatt cgtgcggatg gataattgac cgcttctcta accgtaccga acaaaagata
    25141 atcttttaag gcttcaactg ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc
    25201 ccctagatga ggcaacataa gtatacggtc attttctaag aactcttctt ctggaaaatc
    25261 agtcaagtat ttagccagat gttgtttttc caatgcttgc ataacagcat atttatcaac
    25321 aatttcactt cttcctacat tgataagtac agcatctttt ttcatttttt ctatattcgc
    25381 ctgatcgatc aatccttttg tatcttctgt caacggcagc atgactacga tgtaatccga
    25441 ggtagaaaga actgtttcta aatctgcttg ccgaacataa tccaactggg catcgcggat
    25501 agaataaccc aagacatcca tccctaagct atagcaactt agcgctactt ttgtgcctat
    25561 cgctccaaga ccaagaagac cgatggtttt gccttgcaat tctcgtccca cataagcact
    25621 tcttttgttt tctgcctgtt ctaaaatatt aggacctgtt agtgtttgta ccatacgact
    25681 tgcttcgatt atcggacggg aagataagag caaacagcac aaaacaagct cttttactgc
    25741 attagcattt acacctggtg tattcatgac gatcgtcccg ttttcagaag ctttttcaac
    25801 gttgatcgtg ttcaccccaa caccagctct tgaaattgct agcaaatctg gtgtaagcca
    25861 ttcatctttc actttcgtac tacgaataac tattccttcg gctggcaaat catctattat
    25921 tttgaaatat tccccttgta acttttctat ctcttgttct ggaatagcat caatcaaatg
    25981 aacgtgatac ataaaacccc ctccttacta acaagtatct cgaaatttct gcaattagac
    26041 aactgtttac catttgactt cctagaagca aaaagagcag ttagagcaga gtaggctgag
    26101 tgataaaaat aaggctatga caagttactg ccataagcct tattttcgag agcaaaatat
    26161 tgagggtgag atatcttgat aaatggtgtt ccgttagctg acattgataa taagactaaa
    26221 tttcaaaaaa gttgaaaagc aaatttcgtc aatctcttct tatttcttaa aactaagtgg
    26281 ctttttcaca acctcttttt atctaataac cactgtttcc aactcaacta attttgccca
    26341 cgtttcaatt tgatctgttg ttagatttag cgagacaacg gtatgatgac cgccacctgc
    26401 ctgaatccat gaatggacac cttcatggaa attcggttta gttttccata acacacgtgc
    26461 aacaggtaaa ttaggtgctt cagtcgttgg ttcaaaggct tctacttcat tgatcagcag
    26521 tttataatgc gtaccgaaat ctgccatcga tacgactacc ccttctcctg ctttcccatc
    26581 aaatacaaga cgcgccggat cttctctatc tcccattgat aaaggagaaa caacgattct
    26641 tggtttcgtc gcagcaagcg tcggatctac ttccatcata tgggattcca agattgcttc
    26701 ttggccacta gctagctcgt aagtataatc ttccatgaat cctgtatctt tccctcgagc
    26761 catgattttc agcaaccgat caatcgctgc agttttccag tcgccttccc cagcaaaacc
    26821 gtatccttct gccatcaaac gttgtacagc tagtccaggt agttgtttca ttccatacag
    26881 gtcttcaaaa ttagtcgtaa aagcgttata gcctccttct tctaagaaac ggcgaatacc
    26941 gatttcctgc tgagcttgta cttttacatg ttcctcccat gtcttttctt cataatcacc
    27001 atagtcgaag gtatacaatt ccttgtactc ttcaaataat tgatcgactt cttcgtctga
    27061 tacgcgatcg attacttgta caagatctcc gataccaaaa taatcaacag tccaaccaaa
    27121 ttgaatctgt gcttccactt tgtctccttc tgtgacaccc acgtttctca tgttgtcacc
    27181 aaaacgagcc acttttattc caaaattata tgggatttta gattatcttt ttagaagttc
    27241 ttgaatgtcg gtatagcccg tgtttccggg cttttccggc atttttgata ttgttagata
    27301 cttacaaatg ttcttattac ctctcaccat ttccccctca aaagtagtaa atggagtagt
    27361 aaaaccggcc ttgtgtcagg ctgccagccg ttccatttct gcccttgcgg aatcgaatgt
    27421 ggcgtgtgca taatagttca gcgtcatggt gatattggaa tgtcccataa tgtactgcaa
    27481 ggctttgggg ttcattcccg cattggctaa ccgggtgcag aatgtatgac gcatagcatg
    27541 gggcgtcgtc gttttcggca acgcttcttc atggctcttg ttgtacttct tcacaagcct
    27601 gccaaacatc ccgccataat ctaccgccgt catgggatag ccgttctgtt tgagaaacag
    27661 gaaattggca tacccgtcaa taatgaacgg ctttgcacct ttgcggtttt ttatcactcg
    27721 ctggaacgcc tgatacactt cctcattcat ggggattttt ctgacgccgc tttgggtctt
    27781 gggttcgtca atatagtaac cgacgccggt atttctcaaa agctggtggc tcacgatgat
    27841 tacccggttt tcaaaatcca aatctttgtc cgtcagtccg cacagttccg aaatgcgaag
    27901 ccctgtcccc agcagaataa cgattgcgtc ataatgcttt tggtaaacct tatcaccttg
    27961 aataaaggac agaaaacttt cttcctgtgc tggtgtaaga ggcacctttg gttccgtatc
    28021 gtcgtccaga acgtcactaa gctggaagtc aaacgggttt tttcggatgc aatcgtcctg
    28081 tatggcggtg taaaaagccg ctttcaggga acgcttgtcg ttattgatgg tcttataaga
    28141 aaggcccttt tctttcatcc gaagcgccca ttcctttgcg tcggacagct tcacactgtc
    28201 aatcgggcag ctccccagcc gatcttgttc cagaatacgc atcagccgtt cccggcccag
    28261 tttggtgttg tgcttcacat tgccccggtg cctgatctgc ttggcgtaga gctggcagac
    28321 ggtcattttc ttgccgatgg tgtctatccc gtcgtcaagg tctttctgga tttctttctc
    28381 cttttcccgg agtgaaatat cctcccgttt acctgccggg gtcttatccg taggcactaa
    28441 cttccatgag taaacaaact gcggttttcc aaaggtatca acatatttgt aagcatatcg
    28501 tccgtctttt ctctggctct ctccagaccg caaaacgcga tttttgctgt ctcgtctttt
    28561 ttctgacatc tcgtcatgct cctttccatg acggaaagag ccgcatatat gcttataaat
    28621 tattataaca tatctgcggc cctttttcac tattagattg tgtccaaagt gtcaattatt
    28681 ttctcaaact gcttgcgttt gatctggatg cggttgccat tcataatgac ccagccagag
    28741 gccggatttt cctcggccag cttacgcaat ttgttttctc cgatacggaa atatttagac
    28801 gcttcctcaa tcgtcagcgt gtatttttcc caaataggca catcatggtt cataatgcag
    28861 ccccctttca caaattcaaa ggtttgtgtg atttaggggc atagacggac ggctgctggc
    28921 acagctccac gggactttca cccccgcgtg gttctcacgc ggccctaccc attgcctgcg
    28981 acgcttttaa cgctcggact gtggctataa gggagtatca tagtcctgcc tgtacgtcgt
    29041 cgcccgcaag ccgccacgct cacattgcgg cgtggtgttc ctcgctccgc ttttcccgta
    29101 gggaaaagta tcatggcgca ccagccgtcc ggctcggcac agacagaatg tgtccgtatg
    29161 ccctatgatg cgccgccgtt atcttgcggg catatttatc aaggtgcgat caggccaccg
    29221 ggaaaacacc gaaacgggga aagggtaagc cgtttcatgc tgccggggcc ggttcgtcag
    29281 ttcgtgacga tagcgtggat gagcttgatt tccagacggc gcttcatggc ctcgtccaga
    29341 cacacatgcg gatagccgtt ttcgtcatag agcgtccggg tacacagctt gttcatgtaa
    29401 ccgctgtaat actgcaaaac gcgctctacg gctccggcat ccccagcgcg ggcggcctcg
    29461 atcaccgaaa ggggcaaaag ctcaatgccc ttgtagttcg ggttcttcat ccgcgtctaa
    29521 cctcccttcg gcatcaacgc ctttagctgt ttccgcagct ccgataaggt atttgtcctg
    29581 tgccgctgaa cggcactccg ggacattccc acaaggccgc cgatctcacc atctgccata
    29641 tccagaacac agtgcaggat taaaatactc tgctccatgc tgggcagcgc ggcaaaggct
    29701 tcggcaacaa gctcattgtt gatatgtagg tcatagccat gcgacgaaaa cgtaaagctg
    29761 tcgctggggt agtgatctac tgtacagagc ttgtccaaat ctgcctgtga caaagagctt
    29821 agtgacactt cacggtcacg gcggcgcttc atttcagcca agtagctttt ggcctcgtta
    29881 cgcagtaccg tcttgcaaaa agcatcgaac atgcaccgcg cttcatagtc gcgggggata
    29941 gcatccatct tctcaccccc tttctgtggg ggacttaggt ggttctctcc ctttccgcta
    30001 acaagacttt gacaaggccg ccagctaccc gctaaatacc tcctttttga aaatttctca
    30061 aaaaattttt ttggggacag ccgggccgca aaagacgaca aaaatcgccc ggcaggtcgc
    30121 aaacctaccg ggcgagaaaa tgctttgcta tgctgctgat ttacatggta tagtacatac
    30181 tcataaccgg aatagccctg tg
//
LOCUS       DACBYO010000029        29957 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.029, whole genome shotgun sequence.
ACCESSION   DACBYO010000029 DACBYO010000000
VERSION     DACBYO010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29957
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.029"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..740)
                     /locus_tag="IVD26_001240"
     CDS             complement(<1..740)
                     /locus_tag="IVD26_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079227.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(870..1817)
                     /locus_tag="IVD26_001241"
     CDS             complement(870..1817)
                     /locus_tag="IVD26_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6079228.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(1946..2710)
                     /locus_tag="IVD26_001242"
     CDS             complement(1946..2710)
                     /locus_tag="IVD26_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP6079229.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(2714..3103)
                     /locus_tag="IVD26_001243"
     CDS             complement(2714..3103)
                     /locus_tag="IVD26_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079230.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            3238..3780
                     /locus_tag="IVD26_001244"
     CDS             3238..3780
                     /locus_tag="IVD26_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAP6079231.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            3928..4560
                     /locus_tag="IVD26_001245"
     CDS             3928..4560
                     /locus_tag="IVD26_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079232.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(4694..4819)
                     /locus_tag="IVD26_001246"
     CDS             complement(4694..4819)
                     /locus_tag="IVD26_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6079233.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(4953..5846)
                     /locus_tag="IVD26_001247"
     CDS             complement(4953..5846)
                     /locus_tag="IVD26_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAP6079234.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(6028..6954)
                     /locus_tag="IVD26_001248"
     CDS             complement(6028..6954)
                     /locus_tag="IVD26_001248"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAP6079235.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(7039..7800)
                     /gene="pflA"
                     /locus_tag="IVD26_001249"
     CDS             complement(7039..7800)
                     /gene="pflA"
                     /locus_tag="IVD26_001249"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAP6079236.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(8044..10275)
                     /gene="pflB"
                     /locus_tag="IVD26_001250"
     CDS             complement(8044..10275)
                     /gene="pflB"
                     /locus_tag="IVD26_001250"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAP6079237.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(10552..13002)
                     /gene="parC"
                     /locus_tag="IVD26_001251"
     CDS             complement(10552..13002)
                     /gene="parC"
                     /locus_tag="IVD26_001251"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAP6079238.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(13014..15059)
                     /gene="parE"
                     /locus_tag="IVD26_001252"
     CDS             complement(13014..15059)
                     /gene="parE"
                     /locus_tag="IVD26_001252"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAP6079239.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(15225..15659)
                     /locus_tag="IVD26_001253"
     CDS             complement(15225..15659)
                     /locus_tag="IVD26_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAP6079240.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            15786..16424
                     /gene="plsY"
                     /locus_tag="IVD26_001254"
     CDS             15786..16424
                     /gene="plsY"
                     /locus_tag="IVD26_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAP6079241.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(16556..17431)
                     /locus_tag="IVD26_001255"
     CDS             complement(16556..17431)
                     /locus_tag="IVD26_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAP6079242.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(17513..18304)
                     /gene="codY"
                     /locus_tag="IVD26_001256"
     CDS             complement(17513..18304)
                     /gene="codY"
                     /locus_tag="IVD26_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAP6079243.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(18322..19722)
                     /gene="hslU"
                     /locus_tag="IVD26_001257"
     CDS             complement(18322..19722)
                     /gene="hslU"
                     /locus_tag="IVD26_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAP6079244.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(19736..20284)
                     /gene="hslV"
                     /locus_tag="IVD26_001258"
     CDS             complement(19736..20284)
                     /gene="hslV"
                     /locus_tag="IVD26_001258"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAP6079245.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(20321..21226)
                     /gene="xerC"
                     /locus_tag="IVD26_001259"
     CDS             complement(20321..21226)
                     /gene="xerC"
                     /locus_tag="IVD26_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAP6079246.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(21424..22800)
                     /gene="trmFO"
                     /locus_tag="IVD26_001260"
     CDS             complement(21424..22800)
                     /gene="trmFO"
                     /locus_tag="IVD26_001260"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAP6079247.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(22769..24847)
                     /gene="topA"
                     /locus_tag="IVD26_001261"
     CDS             complement(22769..24847)
                     /gene="topA"
                     /locus_tag="IVD26_001261"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAP6079248.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(24969..25826)
                     /gene="dprA"
                     /locus_tag="IVD26_001262"
     CDS             complement(24969..25826)
                     /gene="dprA"
                     /locus_tag="IVD26_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAP6079249.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(25882..26649)
                     /locus_tag="IVD26_001263"
     CDS             complement(25882..26649)
                     /locus_tag="IVD26_001263"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAP6079250.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(26642..27502)
                     /gene="ylqF"
                     /locus_tag="IVD26_001264"
     CDS             complement(26642..27502)
                     /gene="ylqF"
                     /locus_tag="IVD26_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAP6079251.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            27762..28160
                     /locus_tag="IVD26_001265"
     CDS             27762..28160
                     /locus_tag="IVD26_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP6079252.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            28397..28939
                     /locus_tag="IVD26_001266"
     CDS             28397..28939
                     /locus_tag="IVD26_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAP6079253.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(29022..29573)
                     /gene="lepB"
                     /locus_tag="IVD26_001267"
     CDS             complement(29022..29573)
                     /gene="lepB"
                     /locus_tag="IVD26_001267"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP6079254.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(29725..29952)
                     /locus_tag="IVD26_001268"
     CDS             complement(29725..29952)
                     /locus_tag="IVD26_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAP6079255.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
BASE COUNT         8046 a         6303 c         5135 g        10473 t
ORIGIN      
        1 tatttaaaat agctattttc tcccaaagag tttccttgat catcgatcaa tccttgtaat
       61 gagcgttcta agataccatg gctttttttc gatttttttt cttctgactg ctttgtttcc
      121 tctaacgttt ttgttcgatt gaatgttcgt acagacggct caccatttct tttttcttga
      181 tacggcgtcg gttctgtatc gaacaacaga taagagtcat ccgttttttt catcgattcg
      241 attaaatgat cctcagaaat tttgctttct ctagggtctg ggataatcga tgcgggtaca
      301 tatttaggaa caaaataaga acgctcccgc accttcgtgt caacagatgc gtttcgtgta
      361 gtatgcttgg actctgtcct tgtttcactt tgtctgacag aacgagagga atcaccaaaa
      421 agtttttttc gtcctgtcga tgtgatttct gattggtaat ggccggtata atccggtaat
      481 tttcctttat gcttttccaa attttcctta cgcggagctg acttcaatcc atttgttgca
      541 cgacgcttgc gacggatttt ctcggtgttc gtgttcgtga aatgaaattc tttcatctgt
      601 tcaaacgggg actgattctg ttcagtcaaa agatcttctt gtccgtcaaa taatactcgc
      661 ttcttgtcgt tggttaattt tacgcctaac tcatcatcgt acgcaggaaa acggaaatgt
      721 tttcgtctga tttctttcat tcaaaccatc cttctcaaaa atggaacttt tctcaataat
      781 agcacagatt cattgttttc agtagcaatg cgctgattat tttaagaaaa tagcgatgaa
      841 tttcataaat atatatatag taataagact taattcgttg tctctctgat aactagttca
      901 ggaaaaaaac gacgataacc ttgactcgcc cctttttctt ctattttttt taacaacatt
      961 tctccacata cttcacccat acgtataata tcttgcttga tcgttgtcaa tttaggtgaa
     1021 ctgatttggt ctaaaaatac cccatcaaat ccaatcacac caaattcttc gggcaagtgt
     1081 cctccagcat ttataatccc tcttactgct cctagtgcta gccgatctga actacataca
     1141 aaacaagttt tatctgtaaa atctgcccag ttttctgtca tatatctttc tacttctgtc
     1201 gaatgatttg gaaaccgcaa gattttacta ggaagatcaa cttccttcat cacagataaa
     1261 taaccagttt cccttgaaat ttcaaaaggc tcgtccactt cgataccgat ataaataatc
     1321 gtttgataat ctctttctaa ggcatattgc gttgcttttg ctgtaccata ttcattatcg
     1381 ctgtctacat aatcatatcc ttcagaattt tccccaaaca agacaactgg tttttccaaa
     1441 cggtcgatcc aatcgaagtc tttttttctg acacctgtga tgatgtatcc atcacaagaa
     1501 ccgacgtcga aggcatcatt tgtaactaat tggagagaat aatgcgcttt accgatccgt
     1561 ttagcgattc ccatcagcaa attcatgtaa tagggctcag ttgtgtcgat ttcttccagt
     1621 ataaataatt tgatgatctg cgaccgattc gtgacaagtg cttttgcagc aatatttgga
     1681 cggtaatcca gttcagccat tgctgagaaa actaactctt tcaattcgtc agtcacctgt
     1741 tccggatgat tgatgactcg agagaccgtc atttttgaaa cattggcacg ttttgcaaca
     1801 tctgctaaag tgggcatgct ctcttccttt ctaacatgtt gtcattctta ctatcaatta
     1861 taccaaattt tcctaacaga gtttattata gcccaaaata aaaaacggaa aatcctctat
     1921 cgtcatgagt gattttccgt ttcaattatt tatacttttt tatcaaattt tttgctaaaa
     1981 aagtggaagc ttcttccatt agtggtattt gtaccatatg tcgctgtgtt tttgaggaac
     2041 gaaaaacaat ttcttttccg taagacttat gccgattttt ttctacaaat cgttccgttt
     2101 gtatataagg gattttttcg tcagcttgtc catgccaaaa gaacagagga cgtccagcta
     2161 acttttccgg ctgcaatgac aaatcatagc tcttaaccca tgaaatcaaa tcaaaatagt
     2221 cttttggtac gacataatta tattccgatg cgcgccttac gatttctttt ccatattcca
     2281 aaggtgcagg ggaacccatc aaacacacgc ccgctactat atgaggatgt ttagccaaca
     2341 aggcgcatgt tgtcattccc cccatcgaaa ccccgccaac tgcaagctga tcatgtagaa
     2401 gacctctttt ttctaaatgc ttgataagtg tgtcaaattc aaacagattt ccgtagatac
     2461 tatcccaaaa tgtataggat ggaatagaag aaaccggctg tttgcgctcc ccatgattca
     2521 tcgcatctgg caggatcaca cgaatgccct gctgcgcaat ttttcttcct tgcgtcaaaa
     2581 ctaactcctt acttgtctgc catccgtgat aatagatgac aacgggaata cgttcctctc
     2641 ttaattcttt cagaacaact tctaacactg gaatatgatg gacagaacgt ttcaatataa
     2701 ttggattcaa ttgttactca cctattttca ttaaatttcc tgatcgccat agcaaccatg
     2761 ctccaacagt tgtctggaac aggttcagtg taccaaataa tataaatgca ggactgaatg
     2821 gctcgggaaa taagcacaga gaacaaagtc ccaccactcc taatgctagc gaaaggagtg
     2881 gataaataga aaaattcaaa aaactggcaa cgctaccgaa aatattacca ataaacagta
     2941 tcaaaaagaa aaaaacgctt aaaattaaac catctgtcag cgacatctga aaaacaatgt
     3001 tctctacctc aattggctgt tgaatcgaat agacacctaa gtatatactg agaaggagac
     3061 ttagcacgtg gctggcacaa aacacacgat tgaccgtttt cattttaatc acctaaccta
     3121 tctttataat tctattataa tcattttatc atttttttgt atgtataaag tttcaatttt
     3181 tcttcactta cgattttttt tgatattgtt gttatataaa tgaaaggagt tttacaaatg
     3241 attgatccaa aaatgttggg gatgatcttc ctcattaatt ttgcttatat cactctgaac
     3301 acgttacgtt tcatgttgac aatgaaaggc tatcgactga ttgctccact tgtcagtatg
     3361 gtcgagatca cgatttatat cgtcggctta tcccttgttt tagatcgttt agataatcca
     3421 ctgaatttat ttgtctatgc gttaggttac gcagtaggta tcagtgtcgg aattttgatt
     3481 gaagacaaat tggcattagg atacatcatg gtcacaacga ttttgccagc aaatagcgca
     3541 gaagataaaa gtttgccggg tatactgaga gaacacggtt atggtgtgac acagacttct
     3601 gcaatggggc tggaaggtga gcggctagtt ctcgaaatac tttctcctag aaaaagcgaa
     3661 cgtgaactgt atcgcctgat caaagaaatc gaagagcgtg cttttatcat ttcttatgag
     3721 ccaaaatata tttcaggtgg tttctggact aaaaaagtga gaaaacgaca aggaaaataa
     3781 ctcacaaact taaaaactgt ctaatatcta aattaaattt taaatgttag acagttttta
     3841 tttattattt tgattaaaaa acatcgacat atactcatca atttgttatt atactttata
     3901 tacttatcaa tttaatttgg agatattatg gaaattcaac gtagaaccac taatttttta
     3961 catttaggct ctttttttgc aactttgacg atcttatttt ttctatgtta ttcatacctt
     4021 aagacctcac atgcgccttc tagtgcatta ggctggttgc ttttggatca ttctgatatc
     4081 acagaagccg aagaaaatcc gttttttttg attttgtctt ctctttgcgg cttactgttt
     4141 tctgtttatt tcggtgccta tttttttcat cgacatcctg gtacgttaaa cgaagcttca
     4201 agcgtattga ttgcatttaa aacgttttct tttttagcaa ttctttttta ttcgtttaat
     4261 cacaatacgc ttttcttctt tatcatgaat ggtttagtcg tgattttatc catttttact
     4321 tattttattt tttcactcat ttttagccaa ttgaaatgtc cgctcttctt tcgattagtt
     4381 cctgtcacct gttttattta cagcttgttt tccttttttg tccttgcttt aatgccactg
     4441 accaaccctt cgacgatcca agtcgcagga aatctgttgg atatgctctt catcgtcagt
     4501 ctaggtgtat ttatgtggca aagaaaaaac aaacaaaata aaaagcattt tgaagcctga
     4561 ctattacgac ttcataaatg cttttttagt tttaaacact tcaatctaaa agaataaccc
     4621 aagattggat aaattattaa tgactcgcca ttcgtttctt agtgattctg gattatcaaa
     4681 tggacttcct aatctaatca gctagttctt cccataaaat gccatacttg actgaatcat
     4741 aatattgatt atttaaaaat ctaacttttc ttatcactac ttcctttgtc attccacatt
     4801 tctcaccatt tttttgcatt cctttgtttc cagaccatgt agtgaatcta ataggtggta
     4861 gataggcaaa atactcaaat aattctttta accataaagg aagagaaagg ctcctcctgc
     4921 aagagtcagt ataatttttg cttactgctc tcttaggttt tactcactaa aactgttcca
     4981 tattctttga tataagaaaa tgcatgcggt ataaatttct tgctcagctc agaaaagatt
     5041 tgtcgtttaa gaaaggccat ttcctccatt gtcaatgaag gatccaatgt tggtaattca
     5101 atctcaaaat tgtttttttc gacaataggt aattctaatg tgaatgattc ttcttccttt
     5161 atagtattcg tcacaagtag agactgatgg aaaatactag gccggcgatt tttatattta
     5221 ttcttacgta tcctgtcaac gataacttct atttgatcaa aaaagtacga ttcatttacg
     5281 tctccaataa gttcggctaa ttctttgaat gccttcgtta caggaagctg attcttctgt
     5341 acaaaaaagt aattagccaa agtaagcggg aagtgttcta tagaggaaag tgtgataaaa
     5401 cggtacttct catttcctgc agttgtcctc agcaattctg tctctcggct gtttcttact
     5461 ccataaaaat acgcttcttt ccgttcatct tcgaaacaat acgcccaaat aacttctccc
     5521 atcgctaatt tttgttcatc aacagagagt ctcttcaatt gttcagctat ggtttcagca
     5581 gccgaagtgg cttgttgcaa gtaatcttta ggatcaaata ttggaaagtt caaatgatat
     5641 cttcgttctt ccctcttgat taatcctgca tcgatcaata aatcaagaaa atgggaaaat
     5701 ttattttgcg aaaattcttt tttcaattct cttagaatcg tttcttgttc tcgatgttca
     5761 tatagataat cggtcaatga agaaaaaagc ggatcatcgg tcagtttttg ataaaagttt
     5821 tccttatttt ttgaataata gttcatatat gttctctttt ctatccgttt tattttactt
     5881 aaaaggcttt tacgtaaaaa ggaggaagaa caagagtcat aattgactgt tattctcctc
     5941 catttcttcg gcctttagta tgttctatgt ttctttttat atcaatcgct tatccattca
     6001 ttttgaatgc ttcatactac catttgatta gctaaataca gccgtcaatt gaggtacgac
     6061 ttgtttttta cgtgaaacga cacctttaag caaagcacgg ttgttggtca aagttgtttg
     6121 gaaagcttct tctacttttt cttttccttt accagcaaca agtaattctg aatcactgtc
     6181 taagatgttt gtgacaacta atacgaacag atcgtagcca tttgctttca tttcatcttc
     6241 cattgctgct tctagctctg cttgtcgatc catcacttca ttaaggtcca ctgtattgac
     6301 ttgagcgata cgaacgttgg aactgcccat tgggaaactt tttgcatcca aatcaagaag
     6361 aaccgcagct gatttatcac ttagatttgt tcctgctttc aacatttcaa gtccataagt
     6421 gtttagatcg acttcagcga ttgctgcaag ttcttttgca gctgcttcat cttcaggcgt
     6481 acatgttggt gatttgaaca acaatgtatc tgaaatgata gctgagagca tgattcctgc
     6541 gatttcttta ggaattgtta cttggttttc tttatatagt tttaaaataa tcgtacttgt
     6601 acatccaact ggttctgcac gatagtacaa tggattagct gtttcaaagt ttgcaatacg
     6661 atggtggtct actacagcta aaatatttac ttcgctgata tctgaaatac tttgttggaa
     6721 ttcattatga tccacaagca tgacatctgc attttctgct ttagctgact ctactactcg
     6781 tggtgcagat agctgaaagt ggtctaatgc gtattgtgtt tcttcattag gtgtacctag
     6841 agcaactgct tctgtttctt tacctaattc attttgcaag tgtgaaaacg caatggctgc
     6901 cccgattgca tctgtatctg gattttggtg accaaaaact aaaatttttg acatgtcatt
     6961 cgctcctttg tgatttctcc tatttaataa tagcaaaaaa acggaaagaa gcaatactta
     7021 tcttctttcc gatgcgacct atcgcgttaa atattttgta tactcttctg tatgaagcaa
     7081 tcgtttagca ttttcgacac gttcttttgt aggtggttcg atcccttcta atggatattt
     7141 caaaccaagt gtttcccact tgtattttcc catcgtatga taaggaagaa tctctactct
     7201 gtctacattt gacaaggttt gaataaagtt gtctagtcgg atcaaatatt catcataatc
     7261 acttcgctca ggaactagta catggcgaat ccaaaccggt ttgttgattt ttgacaaata
     7321 ttgagccatt tctaaaatat tttcattgtc ccaatgcgtt agttttttat gctcttcatt
     7381 atcgatgtgt ttgatgtcaa ataacagtaa atctgtatac ttcatcaatt cttgaaaacg
     7441 tgaaaagaaa ggttcttcat acgtaaaagg ttttccgcat gtatccaatg tagtatgcat
     7501 cttccgctct tttgcttttt taaatagttc gatcaaaaaa tcgatctgca atagaggttc
     7561 tccaccacta acagtaatac cacctttatc tccccagtaa ggtctgaagc gttctgcttt
     7621 atctaaaagt tcatctgctg tgtattcttt ccctccgcca atattccaag tatctggatt
     7681 gtgacaaaat tggcaacgca tgcggcatcc ttgcataaac acgacaaagc gcagtccagg
     7741 tccgtctact gaaccgaaag tttcgataga atgaacatag ccgattgttt tttcttccat
     7801 ttaagttcac atcttttctt tgatttcatt ttaagtacaa gttagctgtc gaagcgaagc
     7861 tttctgaaca aaatttttcg caattgccgc ttcgttatgt gtaaaattta cagggacgga
     7921 acatacaagt cctgcccctg taaatcgttt ctttcaaata agcatactga ttattcgatt
     7981 ttgatgcgat ggctattcaa cgtcctttcg acgctaagtc gaaaaacttt tttcacgaac
     8041 tttttacatt ctgtcgtgtg aagttctcat caagacatct aattgttgtt ctcttgtcaa
     8101 gtcacggaat ttaactgcat aaccagatac ccggatcgtc aagttcggat atttcattgg
     8161 attttccatt gcatcacgca ataaatcatt actgaataca ttgacattca aatgataagc
     8221 tccttttgag aagtatccat ctaagacatt acgcaagttt tcgattcttg tatcttgttc
     8281 ttttccaaga cctgaaggat tgattgtttg ggtatttgaa attccatcca atgcacagcc
     8341 gtaattcatt ttagctgttg agttcaggct agctaataac ccactttgtt ccgcattgta
     8401 acttggattt gctcctggcg caagtggttt tccagcttca cggccatcag gagtatttcc
     8461 tgtattttta ccgtaaacaa catttgaagt aatcgtcaat aatgaagttg ttggttttga
     8521 gttgcggtaa gttttatgac gtttgatttg tcccatgaag tattccaaga tccatgaaac
     8581 taattcatct gcacggtcat catcatttcc gtatttaggg aagtcgccat ccacttcaaa
     8641 atcaactgct attccttttt cattacggat tgcttttact tttgcatatt tgatcgctga
     8701 caagctgtct gccgcatgag agatcccagc aatacctgta gcaaatgtgc gttgcaagtc
     8761 agaatccatc aaagccagct gagctgcttc ataagaatat ttatcatgca tataatgaat
     8821 gatgttcaac gtattgacat atagttctgc taaccaatcc atcatattca tgaagttatg
     8881 tttcacttct tcaaagtcta gtatttctga tgtgattgga cgatattctg gtccaacttg
     8941 ggcgccagtc acttcatcga ctccgccatt gatggcatat aatagtgttt tagccaagtt
     9001 agcacgagcg ccaaagaatt gcatgtcttt tccgacaact gttcctgata cacagcaagc
     9061 aatcgcacaa tcatcagaac cccattgttc acgaagctga ttatcatttt cgaattgaat
     9121 cgaagaactt tcgatagcga ttctgctagc atatgttctg aatccttctg gaaggtgttc
     9181 agaatacaaa acagtcaagt ttggttctgg tgaaggtccc atatttgtta atgtatgaag
     9241 cagacggaaa tcattctttg taactaatga acgaccatct aatcccatac ctgcaatgga
     9301 taaagtagcc cagataggga atcctgagaa taattggtta tattcaggtg tacgcgcgaa
     9361 tttgaccata cgtaatttca ttactaagtg gtcgatcaat tcttgtgctt ctttttctgt
     9421 gattactcca ttatccaaat cacgttggat atagatatca aggaatgctg agatacgtcc
     9481 gattgacatc gcagcaccat tttgtgattt gattgctgct aaatatccga agtatagcca
     9541 ttggacagct tcttttgcat ttgcagctgg tttagaaata tcatagccat atttcgcagc
     9601 catttctttc atttgcgcta atgcacgata ttgttcagtg atttcttcac gtaaacgaat
     9661 cacttcttca ctcattgtat gataaccagt catatcatga tcttttttct tttgttccat
     9721 caaatagtcg attccataca atgccacacg acgatagtca ccgatgatac gtccgcgacc
     9781 gtaagcgtct ggaagccctg taatgatttt gtttttacga gcagcacgca tttcagcagt
     9841 ataagcgtca aatacacctt gattatgtgt tttgcgccag tcagtgaaaa tatgtgtcaa
     9901 ttcatcgttt ggtgtatagc cattgctttt tagcgcattg ttagccatat tgattccgcc
     9961 gaacggcatg aatgcttgtt tcaaaggttt gtctgtctgt agaccgacga ttttttccaa
    10021 atctttatcc aaatagcctg catcgtgtga agtaatagtt gatacgattt ctgtgtccat
    10081 atcatagaca ccgttacgct cgaattggat atcatttaac ttttgcaatt catcccataa
    10141 tttttctgtt gcttctgttg ggccttccaa aaagctgtca tcaccgcgat attcagtgta
    10201 gttattttga ataaagtctc tagtgtctac gccttctttc catttggtac ctttaaatcc
    10261 attccattgc tccattgtat ggacctccta aatttctgtt ttatgtaaca gtttttacgt
    10321 gattagtata acacagcacc ctatctttgc aagggttttc ttgtttttta tttaacaatt
    10381 tttatgtttt atttacatat atttaaatca acgttgacat accaacattt aagcattgtg
    10441 aacactttca tctttttttg caaacgtata aggatttatt aaaaatgaat gaaaaagaga
    10501 cgccacctgt attaatacag atggcgtctc ttcattaaaa tactacaaca gttacgactc
    10561 gatgaaaatc tcaggagcat cgataacttc gatgacttct ccaccttttt tctcatccat
    10621 cgcaaatgat ccattcgatg ttcgatcacc tatagggaaa tcagttgggt caatcgttaa
    10681 ctgctgccct ttttgattca tcaaggttat ttcttttgat cttccttccg acatatagat
    10741 aatacggtgc ggattttttt tcagctcacg catgaccgtc actccccgct tcgcacgtga
    10801 agtttggctg atttcttgag caagcatgcg tttaacagct cctcgctgag taacgattac
    10861 gatcggcgta tcaccttctg ctaacacaag cagcccgttg ataatcctat ctccatcttt
    10921 caaattcata gacttcactc cagctgcctt tgctccaaca acgggaacat ctgttaaagg
    10981 atagcgcaaa cccattcctt gatgcgttac taagaaaaca tctaagcctg gctgatcttc
    11041 tttcagatac acagcaatca gttcatcttc ttccgccttt agcttcatac agctgagcgg
    11101 acggctctta taggtgcgcc atggttcgaa ctctgtcatt cgtgtttgct tgatcaatcc
    11161 attcttgctg atgaatacaa atgttttctc tgcttgaatt ttttgatatg ggaaaacagc
    11221 taaaatcgat tcgtctacag acagattgga gattgtttga gaaatgtgct caccagcatc
    11281 tttccatttc aaatcgggta gttcatggac agggcggtag atcacatttg ctttatttgt
    11341 gatcagaaga acatggtcca atgtactcaa ttcacctgag tatagcaagt agtcgccttc
    11401 tcgcatcccg atttcttctg gtttggaagc actataagaa cgaaggcttg ttcgcttcac
    11461 atagccttct cgcgtcacac tgacaattac gtcttcttgt gccactaaga cttgcgtatc
    11521 aattttgatt tcttcgattt cgtcttcgat tgtcgttaga cgagcggaag aataattttt
    11581 tttcacttct cgcaattctt ttttcataac agagaaaagc tctttgtcat ttgaaaggat
    11641 tttattcaac tctgtgattt gcgcaatcaa gctttcggat tccttttgaa gctctgtgat
    11701 atccgtgttc gtcaaacggt ataattgcaa tgtgacaatt gcttctgctt gttcttctgt
    11761 aaattgaaag acgtcgacta aattcttttt ggcgtctttt ttgtctttac tttcacgaat
    11821 cgttgcgatt acttcatcca gaatcgataa agctttcatc aatccttcta cgatatgctg
    11881 tcttttttga gctttggcta aatcgaattg actacgtttt gttatgactt gctttcgatg
    11941 ctcgatataa cttcttaaaa tgtctttcag tccaacttga tgcggagtca tatggtcgat
    12001 agcgaccata ttgaaattgt aattgatctg tagctcagtg tttttgaaca aataattcaa
    12061 aattccttga gcattggcgt cttttttcaa ttcgacgaca atttgcagac ctgttctatc
    12121 actttcatct cgtacttcag ctattccatc gattttctta ttcaaacgga tctcatccat
    12181 ttttttcacc aaggtcgctt tatttacttc atatgggatt tctgtgatca cgatttgctg
    12241 tttattaccc ttcattgcct ctatctttgt tttcgaacga agaataactt ttcctcgtcc
    12301 tgtttcataa gcttttttga tttcatcttt tccttgcaag atccctcctg ttggaaagtc
    12361 aggtccagga atatattcca tcaatttttc aaggctcgct tgtggatgat cgatcatata
    12421 gattgtgcca tcgatcactt cagctaagtt atgagtcggg atttctgttg catatccagc
    12481 agatatacct gtcgatccat tgacgagaag gtttgggtat cgagctggaa ggactgttgg
    12541 ttctttttct gtatcatcaa aattccacac gagatcgact gtttctttct cgatatctgc
    12601 tagcatctct ccacttaact tggataatct ggcttcagta taacgcatcg cagcaggtgg
    12661 atcaccgtcc atactcccgt tattcccgtg catttcgatc agtacttccc gcaacttcca
    12721 gtcttggctc atgcggacca tcgcttcata aatactgatg tcaccatgag gatgataatt
    12781 ccccatgata tttccgacag attttgctga tttacggaat cctttgtcat acgtattgcc
    12841 atctttgttc atggcaaata atatccggcg ttgcactggc ttcaatccat cacggatatc
    12901 aggcagtgca cgttcttgga taatatattt ggaataacgt ccgaagcggt cacccatcac
    12961 ttcttctaaa gttaattctt gtacttcttg tcgattttcc atcaggtgac ctcctattct
    13021 acttcaaata actgattgtt ttcattttta tctgctcgtt cttcatctaa taaatcatta
    13081 gaaactgaag gagagatttc agtatcctct tttttatcta agatactgcc atcttcttcg
    13141 agcgtaaatt gcacgtgatt ttcgatccat tttcttcgag gttctacttt gtcacccatc
    13201 agtgtggtta ctcgacgttc agcttgcgca gcatcatcga tacggacgcg gatcaacgta
    13261 cgggaagtcg gatccatcgt tgtttcccac aattgttccg cattcatctc tccaagtcct
    13321 ttatatcgct gcagcatata tcctttgccg acttttttaa tcattgctgc caattcgtca
    13381 tctgtccacg catattcaat gacttgcttc tttccttgtc ctttggatac tttatataaa
    13441 ggcggtaacg cgatatatac tttcccagct tcaatcagcg gtttcatata acgataaaag
    13501 aaagtaagca gtaatacttg aatatgggcg ccgtctgtat ccgcatcggt catgatgatt
    13561 actttgtcgt aattacagtc ttcgatagaa aactcaggac cgactcctgc accaatcgta
    13621 tagatcatcg tattgatttc ttcatttttc aagatatctt gcattttagc tttttcggta
    13681 ttgatgactt ttcctcgtaa aggtagaatt gcttggaact ttctgtctct tccttgttta
    13741 gcagatccgc cagcagaatc cccttcgact aaatacaatt catttttctt agggtttcgg
    13801 gattgtgcgg gtgtcaattt tcctgaaaga agagattcgc cttttttacg cttcttccca
    13861 tttcggcttt cttctctggc tttacgtgct gcttctctcg cttctctggc tttgattgct
    13921 ttacggacca acatctggct catttcgcta ttttcctgca aataaaagcc catttgttca
    13981 ctgatgacgt tatctactac ggtacgagca actggcgtac caagtttttc ttttgtttgc
    14041 ccttcaaatt gcagaagatt ttcaggtaca cggatagaaa gtacagcagc taacccttct
    14101 ctgaaatcac taccttccag attcttgtcc cgttctttca gcaaaccaac ttttctcgca
    14161 tattcattat aagatttcgt catcgccgct ttcataccag cttcatgggt tcccccatct
    14221 tttgtccgaa cgttattgac aaaagataaa acattttctg aataaccgtc attgtattga
    14281 taagcgacct ctacttcgat accttctttt tctcctgaaa aataaacaac tggtgtcaat
    14341 gtatcttttt cttcattcag ataatcaaca aattctttga ttccttcttc gtaatgaaaa
    14401 atttccttga ctggttcttc tccacgaaga tcagaaagag agattttaac gccttttaga
    14461 agaaaggcag attctcttaa ccgttcggct aaaatttcat atgaaaattt cgttgtactg
    14521 aatattgtat catctggtaa aaaatggaca gtcgtcccgt ttgctttttt tgtttttcct
    14581 atctttttca aagtaccgtc aggtttaccg ccgtttttaa atttctgctg atactctacg
    14641 ccatctctaa cgatcgttac aattagccat ttcgataagg catttaccac actggctcct
    14701 acaccgtgca gtccaccaga agttttgtac cctccttgac caaactttcc gccagcatgc
    14761 agcacagtaa aaatcacttc aactgttggt attccggaag catgcattcc tacaggcatc
    14821 ccacgtccgc tatctgcaac agttatacta ttgtcttcat ggatggtcac atcaatctca
    14881 ctgccataac ctgataatgc ttcgtcaact gcattatcga cgatttcata gactaaatga
    14941 tgcaagcctc ggctgtcagt ggatccaatg tacatccctg gtctttttct aactgcctct
    15001 aatccttcca atacttggat ggacgagtca ttgtattcgt tgtttacttt ttttgccaag
    15061 gcaaacgctc cttcaataat actttgcggc aaaaccgcac cacgattatc atactagaaa
    15121 aggtcgtgaa aaaaaagagg gtagacgaga aatcaatttt aattatctcc taaccgcttt
    15181 ttcgacattc ccctctatcg atcatctctt ctttgtggtc atttttattt ttggttttct
    15241 ttcaacttac caagttcaat cttaatacaa cgatccatta cgatatctgt acgtcctgct
    15301 tttcttagca tctcagctgc ttctttgttt tcaatcccta attgtgccca gaacacttta
    15361 gcatcagttt tcaaaaaatc acctgctatt tcaggtaaaa attcactccg tctaaataca
    15421 tctacgatat cgattggatc atcgatttct gtcaaattcg catagacttt ctcgcctaga
    15481 atttcttcac cagccaataa tggatttact ggtatgattt tatatccatt gtcttgcaat
    15541 acctgtgcaa ccatgtaact tgttcgttct ggtttattgc tcaagcctac gacggcaata
    15601 ttttttgctt cttccaaata gttgaaaatc gtttcttgtg ttggattttt tacagacatt
    15661 tctgccaccc cttgcttttc tttttattcc atctattata cttgtatctt tcattttttc
    15721 aattgttcct gttacctatt catgctaaaa taaaggatag ttttcaactt gaaagagggt
    15781 aaaaaatgaa attgatctta ttacttattt tagcatatct tttaggttct attccttccg
    15841 gtgtctggat tggcaaattg tttttcaaaa aagatatccg acaacacggg agcggtaata
    15901 ctggaacgac caatacattt cgtgtattag gcaaaacagc cgggattgtt gtcctgctta
    15961 tggatatttt aaaaggtaca ttggctactt gtttgccgat gatcttccac ctttctggga
    16021 ttaaccctct ttggtttggg gtatgcgcca ttcttggcca tacatttccg atttttgctg
    16081 ggttcaaagg aggaaaagct gttgcgacaa gtgcaggaat gcttttagga tttaatcctg
    16141 tattttttgt ttattcttgt atcatcttta tcgttagttt attttgtaca agtatggtga
    16201 gtttgagcag tatgatcagt gcagtattga tcactttatc tacgatcgtc cttccttatg
    16261 tagctcctgt gattttggct aagcccaatt ggttactgac gatcattgcc tttttagttt
    16321 cttcctttat cttttatcgg cataaagaca atatcaagcg tatcagaaac catactgaaa
    16381 gtcgaatccc gtttggtttg aatagcagca agaaaaaatc ctgatacttt ttcattccaa
    16441 agagataaaa cgggagtgtg acaaatcgat gtcacactcc cttattactt acaggatagc
    16501 ttttttacac accttggtaa acggtgttcc ctgctaactt ctcggtcaca acctcttact
    16561 tcactgtgat ggaatatttt gtcttgaaga tttcatgggc acctagttga ttgatcccta
    16621 ctttttccat caagtttcca ctactgttca ccgtgtcagc gattccgcac cacggttcga
    16681 tacaaacgaa aggcgcttct tttggataag gagaccagat ccctacataa ggcatatctt
    16741 tatagcttaa agttacgcta tgggaagatt tttcacttcg aatggcgtac gcatttagac
    16801 cccttgtttc aaaaaccaag gcatcttgct caaaaagttc acgattcaaa gccagattcg
    16861 tatttgtctg acctaacgtc ttttgatcca tatcgatgaa tgggcctttc aatggtaggc
    16921 gtaatcttga tttcaatgga gaaaatgcca gatagaaatc ttcaaatgac aatccttctt
    16981 caagaggtac attgaaagca ggatgtccac cgatagaaaa gaacatttct ttttcaccgg
    17041 tatttgccac ttgataatga accgtgatgc cgtctcctcc taattcatag ctgatcacta
    17101 attcaaaatc aaatggatac ttttctaatg tctccggcgt actccttaag atgaaactag
    17161 ccatttcttg tccatgttca atgacttcaa aatccatatc ccgagcaaat ccgtgttgcc
    17221 ccatttgata tgttttccct tgataaacat actgatcatc ttttaaacgt ccaacaaaag
    17281 ggaataaaac cggtgcatgt ctgccccaat acgctggatc accttgccag atatactcta
    17341 aaccatgttc ttttgatttc agactgatca attccgcacc gtgttcagcg atttcggcga
    17401 tcagctggtc attttgaata ataacagtca ttgccattcc tccaacttcg acttactttt
    17461 taaaatggga aggctggaac aaacatttct atctgcccca gtccccttac ttctaataac
    17521 tgtgttttgc taactcgtct ttaaaacggg aattcaatac ttttaaataa gttcccttca
    17581 tgcctaacga acgagattca atgattccag ctgattccaa ttttcgtaaa gcattgacga
    17641 tcacagaacg agtgatgccg atactatcgg caatattaga agcagtcaga cgaccttcat
    17701 ctccatccaa tgcttcaaag atagcttgta cagccttcaa ttcgctataa gataatgtgt
    17761 tgattgccat ttggacagcc gttgcactcc gtacatctgc ttcgatgctt cgagacttct
    17821 gataaaggat ctgcataccg acaaccgtag ctccatattc tgctaagact agatcgtcat
    17881 ctgcaaacga ttgttccata cgagataaga taatcgtacc caaacgttcg ccagctccaa
    17941 agatcggaac gacagtcgtc agaccaaatg gatatttctc tcttgactct accggaaatg
    18001 cagtaatatc actagtaatt gggatattag cttcagtttt catcaactgt gccactgtat
    18061 cagtataaga ttcaggaaat tgtttctcaa caaacattgt tttgattcgt tcattgttca
    18121 catcgtgacg ttcattataa cctagtaata ctccgtcact tcctatgata taggtgttgc
    18181 tgtcaagaat accacctagt gtgacagcca ttttatcgta aggcaaatct gcttgcatgt
    18241 caaaagtatt cttttgctgc aaaagtgtgt ttatcttgcg ggttttcgtt agcaagtctg
    18301 tcattgtcgt cctccgattt tttataaaat atagcgactt aaatcttcat ttgccgcaat
    18361 tgagccaagt ttgtcatcca catatgcttc tgtgatcgtt atttctccca tttgcatatc
    18421 tggtgcttca aataatagat cttctagtag tttttccaaa atggtatgca gtctgcgtgc
    18481 gccgatatta tctgtgtcac ggttgacatc gaaagcgatt tgagcgatcc gttcaattgc
    18541 ttcttttgta aacgtaactg acacattttc tgtaccgatc aacgcgacgt attgttttac
    18601 taaagcatta tttggttcgg tcagaatctt cacaaaatct tcagctgtca aatcatctaa
    18661 ttctacccgt atcgggaagc gtccttgaag ttctggaatt agatcacttg gtttagacaa
    18721 atggaaagct cctgaagcaa tgaataggac gtgatctgtt tggatgatcc cgtattttgt
    18781 gtttacttgt gaaccttcga caattggcaa tatgtctctt tggacgcctt ctctggatac
    18841 ttctccagat tgctgtgatt tagaagtgat cttatcgatt tcatcgataa aaataattcc
    18901 actttcttcc gctaatttga ttgcctcact atggatatca gcatccttga ctaattttgc
    18961 tgattcttcc ttgatcaata actctaaagc ttctttgact gttaccgtcc gttccacttt
    19021 tttcttcggt gtcaaagcac ctagagtttc atttaggtcg atccccattt gctccaatcc
    19081 attgttcatc attggtgcag gtttcttttg gtcttcaact tcaatggtta cttcacgact
    19141 atccagtaaa cccttttgta gttgttccaa gactgtacgg cgattgattc gaatatcttc
    19201 tgtcacttct tcttgcggtt cagcggtatt ttgctgacta gcattaaaaa gattcatcat
    19261 ttgttcaaat tgattagtgg attgtttctg ttcttttttg ataccaggta ccaagatttt
    19321 taccaaacgt ttttctgcat tttttttagc acttgtgtat acacggctgt actgctcttt
    19381 ttctacgatt tggatcgcat tttctactaa atcccgaacc attgattcta catctcttcc
    19441 gacataaccg acttcagtaa attttgttgc ttcgactttg acaaatggtg cattgacgat
    19501 ttttgccaaa cgtcgtgcga tttctgtttt accgacccct gtaggtccga tcatcagcat
    19561 attttttggt gtaatatctt gttgcatttt ttcatctaac tgcaaacggc gatagcggtt
    19621 acgcaaagca acggcaacag atttttttgc tgcgtgctgt cctacgatat attcatctaa
    19681 ttcacttacg atttgtcttg gtgtttgttt taattcatac atatctactc acctcttaca
    19741 gttcttctac gataatatta tgattagtaa agatacagat atctgcggca atatttaacg
    19801 cattttctgc aatttctttc gcactcatgt cgttttgagc atagtttttc attgctcggg
    19861 ctgcagccaa cgcaaaattc cctcctgatc cgatagctaa gataccatca tctggtgtga
    19921 taacttctcc tgtacctgaa acaagaagca tttctttatc attcattacg atcagcatcg
    19981 cttcaagttt ttgcatagat tgctgtgtcc gccattcttg agctaattcg acagctgcgc
    20041 gttgtagatt cccgttatat tcgtttagtt tgccttcaaa tttttcttct aaagtaaacg
    20101 catctgcaac acttccggcg aaacctacaa caacttctcc attgtagata cgtcgtactt
    20161 tctttgcagt gcctttcatg acaacagatt cacccattgt tacttggcca tctccagcca
    20221 tagcaaattt cccgtctttt tcgacggcac agatagtggt tgaatgaaat ggtgattcga
    20281 ccatgtttgt ttcctcctaa atttgttctt ttccttattt ttacgctctt ggatggaaag
    20341 aacgatagtt tttttgtaaa ctttcttttg ttacatgggc atagatctgg gtagtcgata
    20401 aattggcatg tcctagcaat tcttggactg tccgcaaatc tgccccatta tttaataaat
    20461 gagtagcaaa tgtatggcgc agcatgtgag gatggatatc actatccaaa ctgctttttt
    20521 tgatcatttg attcaagaca tattcaattc cagtaggcgt gattggtttt ccatgatgat
    20581 tcacaaaaac gatatcatgc tcttcgtgat attttgtcat caatacctgg cggccttccc
    20641 tgaaatattc ttgcagagca tcttgagcaa aagaacctag aggagcatat ctctctttgt
    20701 tccctttacc atggatcaac atgacctctg aatcaaaatc aatgtctgat accgacaaac
    20761 tgctacactc acttaaacgg atgcctgacc cgtaaaggac ttccagtaaa gcgcggttcc
    20821 tcaaatccaa aggactatct cctgctacgc tgtcaaaaag tgcttgcatt tcattttcat
    20881 aaaaaaaacg tggcagtctc aaatttttct ttttgagatg aacgtaagaa aatggatttt
    20941 cttttatcac ttcttctttg agaagatact gataaaacga acgtaggctg gctatcttgc
    21001 gactgataga atttctgcta tagctaggac gatgatcagc taatgcactc aaatagacac
    21061 gaaccgtaaa atattccgcc ttcagcagat cagcgtctcc agattcctcc aaaaaatgtt
    21121 tgaaatggag aatgtcttct tcatatgctt ctttcgtttt ttctgaatat cctctttcga
    21181 caatcaaata acgcaaaaat ttttgttccc acgtggcttc tgtcattttc tcaccttcct
    21241 tttgtcccag agaataattt agcacagcgt ttataaaaag acaaataaat tgtcagaatt
    21301 taaccaatat ttctaagttt gttcacaatt ggcgcaattc ctcacatttt gtttgagaaa
    21361 ttcttaagaa aaacgcaaga aaaagagcga gactatccgt ctcaccctct tcatggagtt
    21421 tccttactca tttgggattg cagttttttc taattctgtt tttattgcct cattagcttt
    21481 taaagctcgt tgtgcaattg cttcatatct tgcttttttg tctcgaatgc gctctggcag
    21541 ttcaggaaac agaccatagt tggcattcat cggttggaaa tgttttcctt ccgcatgagt
    21601 aatgtagtaa gccatacttc caatagctgt ttcttgtgga aactcgactg gttccatttc
    21661 ttttgctaag cgtgcggcgt tgattccagc aagtagtccg ctcgctgcac tttcaacata
    21721 gccttctaca ccagtcatct gacctgcaaa gaacagatct tcgcgtttcg ttgattggta
    21781 agtcggtttc agcaattctg gcgaattcat aaagctgttt cggtgcatca caccatagcg
    21841 aacgaattca gcattttcta acccaggaat catccggaaa acacgttttt gctcgcccca
    21901 tttcaagtga gtctgaaagc ccacgatgtt gtataaagaa gctgcagcat tgtcttgacg
    21961 cagctggata acagcataag gacgtttgcc agttttagga tcttccaatc caactggttt
    22021 cataggtccg aaaagcatcg ttttgaatcc tcgctgtgcc attacttcaa ttggcataca
    22081 tccttcaaaa tatttttctt tctcaaaaga tttaagttct gccacttcgg cattgattag
    22141 tgcctcatgg aaagctttga attcctcttc tgtcatcgga cagttcaagt aagctgcttc
    22201 tcctttgtca tagcgggact tcaaatatac tttatccata tcgatcgtag ctttgtctac
    22261 gattggtgca gctgcatcat agaaataaaa accatctgaa ccattgaatg ctttgatgct
    22321 ttctgctaat ggatgagaag tcaaaggtcc tgttgctact acggtgattc cttccggtat
    22381 ttcagtaatt tcttcgttta tcactgttac taatggatgc tctttgactt ttcgggtaat
    22441 tgtttcagaa aaagaatcgc ggtcaacagc taaggcacca ccagctggca ctgctgtttc
    22501 atctgccgaa gtgattacta ccgaattcaa tcggcgcatt tcttctttca ataaccctac
    22561 tgcattagcc aaactgtttc ctcttaatga attggaacat actagttcag caaaattact
    22621 tgtgtgatgc gcctcagtcg atttgactgg acgcatttca tataaacgga cagggactcc
    22681 tgcttgtgcg atctgccaag cagcttcact tccggcaagc cctgctccaa caacatttac
    22741 cattttcaat gaaagaacct cttttctatt atttttggat gtcttcttcg taatctccat
    22801 ttacacagac tacttgttta ccgcctttga ctttcttctc gaccagatat ccgtcacatt
    22861 ttggacaatt tctgcccact ggtttatccc aagaagtgaa ttcacattct gggaaacggg
    22921 aacaaccata gaatagtctg tttttcttag attttcgttc aatgacttgt ccttcatgac
    22981 atactgggca agtcacaccg atttctttta cgattggttt cgtattccga caatcaggaa
    23041 aattactgca agcataaaac ttcccatatt tccctaattt tatcaccatc ggatgtccac
    23101 agacatcaca atcgaatcct gctggttcat ctttgatttg aattttttcg attttttctt
    23161 ccgcattcgt cagttctttt tcaaacggtt tatagaaacg atcaaccact ttgacccacg
    23221 cttccgtgcc ttcttcaatt ttatccaaat ctccttccat ttctgctgtg aaatggatat
    23281 cgacgatttg agggaagaat tcacagatta atgaattgac aatttctcct agttcagtcg
    23341 gctcaaatct tttttgtgtc aattttacat agtagcgtct ttggatcgta tcaagtgttg
    23401 gtgcataagt ggaaggtcgc cctaccccgt tttcttctag tgcacgaatc aacgtagcct
    23461 cactaaaacg tgctggtggt tgagtaaaat gttgttttgg ttcaatatca acagattgga
    23521 ctacatcgcc ttcttcaagt tctggaagaa tattttcttt ctcttctttg ccgtcatctc
    23581 taccttccac atacacttgc atgaatcctt tgaatttgat ttttgaaccg ttcgcaatga
    23641 agatgacacc attttgttct aatgtcactt tcattgtatc taaaatagct ggtgtcatct
    23701 gactagccac aaaacgtgac cagatcaatg tataaagttt caattgatct ttatctaaat
    23761 attgtttgag ttcatctggt gtacgaagca cactcgttgg acgcacagct tcatgggcat
    23821 cttgtgcgcc ttgagcattt ttgatctttc ggtgatcatg tctagaaaat tcttttccat
    23881 acgtatcttc aataaatgct gcggcctctg cttttgctgt atcggcaatc cgggtagaat
    23941 cagtacgcat gtatgtaatc aagccgactg ttccttgttt acccaaagtg attccttcat
    24001 ataattgctg tgctaccatc atggtttttc ttgttcgaaa gtttaactta cgggcagctt
    24061 cttgttgcag gctacttgta gtgaaaggat tcgcagggtt tcttttgcgc tctttctttt
    24121 ctactttttt aacttcgaag tctgttccat caattctagc agtgacttct tttacacttt
    24181 gtgcatctgg taatttcttt ttcttaccgt cgattcccca gaaatttgct ttgaatttct
    24241 tgcgagcttt tttaaaatta ccgtcgatgc tccaatattc ttctggaaca aattctcgga
    24301 tctctttttc acggtcaata ataattttta aagcgacaga ttggacacgt cctgcactta
    24361 accctttctt gaccttacgc cagagaatag gactgatcga ataaccaacg attctgtcta
    24421 aggtacgacg agcttgctgt gcatctacta aatctacatc gatcgttctt ggttccttaa
    24481 aagctgcttt gactgcgtct tttgtgattt cattgaagac cacccgattt ttttctttca
    24541 gatccaaccc aagtaggtac gctaaatgcc aagcaatcgc ttctccttct ctatccgggt
    24601 cacttgccaa gtaaactttt tgagcttttt ttgctgcggc tttcaggctt ttgatgacat
    24661 cgccttttcc gcgtatagaa atataatggg gttcataatt gttttcaaaa tcgataccca
    24721 ttttactttt cggtaaatct cttatatggc caacactggc cattacttta tagtttcgtc
    24781 caagatattt ctcaattgtc ttggcttttg caggtgattc tacaatcact aaatatttat
    24841 acgccattac tgaatggact cctttccatt gtcgtgttcc tactattaaa agaggattca
    24901 tacaaatcgt agctaatcat atccattcag aaaacgtttg tcaagaaaag caaatgaaaa
    24961 gtatggtgtt attctttaaa ttctgccaag atatcttcac ccgaaaccgt gcaaactgca
    25021 ccgtcttgga tcaaatgatg acatccggta gaatgttctg ttaaaatatt tcctggaaca
    25081 gaaaaaactg ttcttccaag atccaatgct tgctgtgctg ttatcagaga gccgcttttt
    25141 ttcttggctt caaagacaca tgttccttta gacaaagctg cgataatccg atttctcatt
    25201 ggaaaacaat gctttttcgg gccggattga ggaggatatt cactcaaaag aagatgatca
    25261 tttgcaatca cctcttgcaa gtcacgattt tcagcaggat agacttgctc tatccctgtt
    25321 ccaatgactg cgattgtccg tccaccatga gagattgctg cttggtgacc gtatgtatct
    25381 atccctttcg cgcagccact gacgatcaca tatccagctt ctatcactgg ttttagtaaa
    25441 taataaactg tttttttggc taaagcagaa gtgtgtcttc caccaacaac gcttaacatg
    25501 ttacaagaaa gtaaagatag atcaccatta taaaacagta caattggcgg ataggtcaag
    25561 tgaagcagct gagggggata tttgggatca aagcaagtga taaacgactg tttcgattgg
    25621 attttgcccc agttagcgtg aatttcctgc caacttttgc gaaacagctc ccggtgtttg
    25681 gttattttac ctatcttaat gatgtcttca aatccgattt ctttataagg atactgcatc
    25741 atccagttag caagtgccca ttttccttga ctactgattc cttttgtata agcaagtttc
    25801 aataaatttt cttctatttg atacatcata aaaccgcctt tcgtctctct ttctaataag
    25861 atacgtaaaa gcggctgttt tttattgtaa atattttttt acaggtgcaa aacttttacg
    25921 atggattggc gtaattcctt gtcgttcaag tccttctaag tgttcctttg ttccataacc
    25981 tgcattatgc gagaaaccat atccaggata aagcacgtca tattctttca tcaattggtc
    26041 tcgatatact ttagcaatga tacttgcagc agcaatcgac acagatcgtg catccccttt
    26101 gattattttt tcctgctgaa taggcaaatc caaggtcatc gcatcgatca acaaatagct
    26161 tggtacaatg gacaattttt ctactgcttg gatcatcgct aatttacttg cttcataaat
    26221 attcacatca tcgattgtct gctgatcaac gatcccgatc ccgattgcca gggctttttc
    26281 ttgaacttgt tgataaagaa gttctcgctt tttctctgat aattgtttgg agtcattcag
    26341 ccctaatatg atctcatttt tcggcaagat aactgcagct gccacgacag gtccagctaa
    26401 tggtcctctt cctacttcat caatgccggc aatccattgg tgaccttgtg cgtacccttg
    26461 cttttcaaag caaaacattt cttcatattt ttccttaatt aatgcttcct ttttcaatcg
    26521 tcgttcaaaa gaagccagtg cttgctgcac gcctttgcgt ggatcatttc ttaatgattc
    26581 tagtgtagga tcatctattc tctgtatgct tttcaatcgt tctttgatac tttggatgga
    26641 ttcagtcatc acttttttgc tccatttctt cgcaacgatc cagtgtgtat cgtccaagtt
    26701 ttccttgacg aatatcatgc acgactaatt cgctgccacg atcatagtct tctttatacc
    26761 cacgttttgc tgtaatatcc atcagtaatt ccggtgccaa tttttcttct tgctcgattg
    26821 ataaaccata acgatcgctg attcttcctg aataatatcg ggcaaaaaag tctaatccgt
    26881 aaatcgctaa atcatctaaa tggacaagct ggtctttgat cgcgcctgtc agcgctagtt
    26941 ttttgccgat ttcttcatct tcaaatttgg gccataaaat ccctggtgtg tctaacaatt
    27001 ccaactcatt acctaaacga agccactgct gaccttttgt tacgccaggc ttatttcctg
    27061 tctgtgcaat tttcttgcct actagtcgat tcatcaacgt agatttccca acatttggaa
    27121 tacctaagac cattgcccga atagcgcgag gcttgatccc ccgagcagca tctcttgccc
    27181 gtttttcttt caatgcttct ttagccgcag gtactagacc tttaattcct ttactttctt
    27241 gtgccgtgat agctaatgca agatggcctt gtttacgaaa atattcttgc cacagctttg
    27301 tctgttgtgg atctgccaga tccgctttat tcaataaaac aaggcgaggt ttttgctgaa
    27361 tgatctgatc tagcattgga ttacgagaag ataaaggtaa tcgtgcgtct accaattcaa
    27421 atacgatgtc cacatatttc attttttcag aaacttctcg tcgggctttt gccatatgtc
    27481 ccggaaacca ttggatggtc attgttctct ccattccttt cataccggaa tattccccgg
    27541 ctttacttgt ttttttcttt ttcaatataa attcactttt ttattataaa gaaattccat
    27601 ctattagtta agtgaaagtg aaccagtcct cattctatca catcttcact tttttgatga
    27661 tgcaaatttt tattttggtt tctatatatg aatctaaatt tttgacagcg tttcctaaat
    27721 aagagatgat agacgaacaa aacagaaagg agacgaaaca aatgaatagt atggtttttg
    27781 ttaattttcc tgttgctgat gtcaatcgtt ccgttgcttt ttatgaaaag ctgggtttta
    27841 aaaaaaatga agaattttct actgaagaag ctggttcaat ggtatgggat gacacttttt
    27901 ggataatgct tctctctcat gatttttata aaaaatttat aaaagataaa gaaatagctg
    27961 ataataaaaa aacaagtggt gctttgattt cgtttagtgt tgaaaatgcg gatgaagtaa
    28021 aaaaatttgc tcaaattgca aaagaaaatg gtggtacttt ccacgaagta gatatgggaa
    28081 tgcctgaaga agaaatgttt tcattagaag tccaagatct agacggaaat acattagaac
    28141 ccgtatggat gaagatgtaa gcagataact aatctgacgt tttttataac aaaaaaacaa
    28201 aggcggatga tacgataagt attctccgcc tctatttttt ttattcgtac aatctctttt
    28261 ttacagttta taaaagcagt cttctcaccc tttttttaat tgttagatgc cagtgtatgt
    28321 aaatcaccaa tgtgtcatga cacattggtg attttatggt atccttttat tattaactga
    28381 caaaggagag aatattttga acactttgat tgcaaaagac gtttttagat tgcccgaaat
    28441 gaatgcaaga ttgttgtcga cctctgctct tttattagcc cttgatgtca tcttatacaa
    28501 gatagcgatt ggtcctgctt attttcaaat cacattcgga tttttaagta tggcgcttat
    28561 gggttatcta tatggaccga tctgggctgg tttgcttgaa atgttgtcga acactttaaa
    28621 tttcacgata tttggttcag gaacgtttca agctgctttt cttatcacgg ctttccttgg
    28681 tggatttatt aatggcttat ttttatatca taaaaagata aacctgcctt ccgtcatagc
    28741 tgcccaatta ttgattatga tcccagtcag cctttttatc aattcttggc tgatgtctgt
    28801 tttgtttggt gcagatttca aagtaatttt tctaggtaga ttcatcagga atatgatcca
    28861 aatccctatt caaataatgg ttgtttattc atttatcaaa actttagagg ctagaaaagt
    28921 gtttaaacga gctgtttgat tttacgtact aaggtagtaa actgattttg gattaaacaa
    28981 taaagcgtgc agtctcaaca gactgcacgc tttattgttt ctcactggat ccattttatt
    29041 tcatcaagtg gataatagac aaatcttgct ttacctagaa tatcagtttt attgatcgtg
    29101 ccaaacgaac gactatcttt tgaaactctt cgattatctc caagtacaaa ataattatct
    29161 tccggaagct tggattgtcc cgttagctct tgtagtgtaa agtccgtcgt ataggatgca
    29221 tttgcatgat ctgatttcag gtttttagtt agataaggtt ccttaactac tttcccattg
    29281 atcttcaatt gatcattttg gtagctgaca ttttctcctg gaagaccgat tactcgtttg
    29341 atataaatcg tgccatctgc taattgaaaa acaacaatat caaatcgtct gatctccgaa
    29401 aatttttcca tcacaaccat atcaccttgc ttcaacacgt tttccattga attgccttcc
    29461 actggtaccg ggatgaataa aaatccccgc aacatgaacg caaggaatac agaaacaagt
    29521 aagtatttga atacaagcca gaagcgatta atatagcgtt gtttttttgt caatctctat
    29581 caatccatcc ctcttttttt cattctttct ttattataag aaaaatatca aaaaaatgcg
    29641 actagatagc tgaaataaaa ataattcttt caattaggct attggacaaa aaactttttt
    29701 gatcataaag tacaaaacta tctcttatat gtcatgatta ttttctaaat atttttccca
    29761 tgcttcgtca aagatatcca tggacggcaa atagtcgaca ttcagttcca gataattaga
    29821 aatttcttcg tagctagagc tgtgcttagg aaattggatg tctttaccgg cttctgtagc
    29881 gaaaacagat aaagcatcat gtgtgccacc gcctcgcagt gtcattaaat aatgaaaaaa
    29941 gcttcgattc acccttc
//
LOCUS       DACBYO010000030        27392 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.030, whole genome shotgun sequence.
ACCESSION   DACBYO010000030 DACBYO010000000
VERSION     DACBYO010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.030"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..525
                     /locus_tag="IVD26_001269"
     CDS             <1..525
                     /locus_tag="IVD26_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAP6079256.1"
                     /translation="VSDSSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYP
                     DTAITSLELDSDWGSYFYKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKK
                     KEDGLDVDKLITIEEAAKIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKI
                     NSQTGEVLSTEQDD"
     gene            609..1553
                     /locus_tag="IVD26_001270"
     CDS             609..1553
                     /locus_tag="IVD26_001270"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAP6079257.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            1688..3139
                     /locus_tag="IVD26_001271"
     CDS             1688..3139
                     /locus_tag="IVD26_001271"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAP6079258.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            3160..3996
                     /locus_tag="IVD26_001272"
     CDS             3160..3996
                     /locus_tag="IVD26_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAP6079259.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            3996..4655
                     /locus_tag="IVD26_001273"
     CDS             3996..4655
                     /locus_tag="IVD26_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP6079260.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            4781..5470
                     /locus_tag="IVD26_001274"
     CDS             4781..5470
                     /locus_tag="IVD26_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079261.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            5476..6432
                     /locus_tag="IVD26_001275"
     CDS             5476..6432
                     /locus_tag="IVD26_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAP6079262.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            6476..6988
                     /locus_tag="IVD26_001276"
     CDS             6476..6988
                     /locus_tag="IVD26_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6079263.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(7244..7792)
                     /locus_tag="IVD26_001277"
     CDS             complement(7244..7792)
                     /locus_tag="IVD26_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6079264.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(7881..9062)
                     /locus_tag="IVD26_001278"
     CDS             complement(7881..9062)
                     /locus_tag="IVD26_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAP6079265.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGLGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(9298..10806)
                     /locus_tag="IVD26_001279"
     CDS             complement(9298..10806)
                     /locus_tag="IVD26_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAP6079266.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            10965..11156
                     /locus_tag="IVD26_001280"
     CDS             10965..11156
                     /locus_tag="IVD26_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079267.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            11359..12276
                     /locus_tag="IVD26_001281"
     CDS             11359..12276
                     /locus_tag="IVD26_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAP6079268.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            12269..13342
                     /locus_tag="IVD26_001282"
     CDS             12269..13342
                     /locus_tag="IVD26_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079269.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            13490..14008
                     /locus_tag="IVD26_001283"
     CDS             13490..14008
                     /locus_tag="IVD26_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079270.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            13989..14381
                     /locus_tag="IVD26_001284"
     CDS             13989..14381
                     /locus_tag="IVD26_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAP6079271.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            14457..15392
                     /locus_tag="IVD26_001285"
     CDS             14457..15392
                     /locus_tag="IVD26_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAP6079272.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            15525..16304
                     /locus_tag="IVD26_001286"
     CDS             15525..16304
                     /locus_tag="IVD26_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAP6079273.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            16297..16614
                     /locus_tag="IVD26_001287"
     CDS             16297..16614
                     /locus_tag="IVD26_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAP6079274.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            16858..18468
                     /locus_tag="IVD26_001288"
     CDS             16858..18468
                     /locus_tag="IVD26_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP6079275.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            18625..19473
                     /locus_tag="IVD26_001289"
     CDS             18625..19473
                     /locus_tag="IVD26_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP6079276.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            19704..20183
                     /locus_tag="IVD26_001290"
     CDS             19704..20183
                     /locus_tag="IVD26_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079277.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            20216..22444
                     /locus_tag="IVD26_001291"
     CDS             20216..22444
                     /locus_tag="IVD26_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP6079278.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            22573..24216
                     /locus_tag="IVD26_001292"
     CDS             22573..24216
                     /locus_tag="IVD26_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP6079279.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(24289..24834)
                     /locus_tag="IVD26_001293"
     CDS             complement(24289..24834)
                     /locus_tag="IVD26_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAP6079280.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(24857..25342)
                     /locus_tag="IVD26_001294"
     CDS             complement(24857..25342)
                     /locus_tag="IVD26_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP6079281.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(25332..26144)
                     /locus_tag="IVD26_001295"
     CDS             complement(25332..26144)
                     /locus_tag="IVD26_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAP6079282.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(26283..>27392)
                     /locus_tag="IVD26_001296"
     CDS             complement(26283..>27392)
                     /locus_tag="IVD26_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAP6079283.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         8972 a         4992 c         5491 g         7937 t
ORIGIN      
        1 gtatcggact cctcaacaaa agcaagcaca tcttcgtcta gccagacaaa aagttctagt
       61 gaagcaagta ctcagtcaga tatcaaagtg tctgcagctc gtgcgatcga attgttccaa
      121 gataaatacc cagatactgc aattactagt ttggaattag atagtgattg gggatcttac
      181 ttctacaaga tagaaggtgt cgatgatcaa aaagaatacg aagcaagaat tgatgctcaa
      241 aatgaaaaaa tggagacaga gaatccagaa actctagatc gagatgaaca aaatggtcaa
      301 aagaaaaaag aagatggtct ggatgttgat aaattgatca cgattgagga agcagcaaaa
      361 atcgccgtcg acaaagtagg aagcggtacg gcaacagatt gggatttgga taaagattta
      421 ggtactactt attgggaagt caaagtaaaa gacggcaatc aaagtacatc agtcaagatc
      481 aatagccaaa caggcgaagt actgtcaact gaacaagatg attaagaatt tcttcggaaa
      541 acaagagttg atttttcttt tagtcatgat acactagaca aaataacttg tttgaaggag
      601 cgatttactt gagtttagaa acgacctttg ccaatcatat ctttgccaat cctttgatga
      661 atgcatctgg tgtccactgc atgactaccc aggaattaga tgaactggct cattcagaag
      721 caggagcatt tatcactaag agctgtacga tcaatgaacg aaaaggaaat cccgaaccac
      781 gctattttga tgttccttta gggagtatca attctatggg acttccaaac ttaggttttt
      841 cttattatct agagtatgct cttgcgtatg aaaaagtgca ggaaaaccaa aatcaaccgt
      901 tatttttttc cattgccggg atgagtgtcc aggaaaactt ggaaatgctt gagaaaatag
      961 aaaaaagtgg gtttaatggg atcactgaat taaatttatc ttgtcccaat gtgcctggaa
     1021 aaccacaact agcttacgat tttgaggcca cttatgaaac actgaaagaa gtattcagca
     1081 tcttttctaa gccgctagga atcaaattgc ctccttattt tgattttgct cattttgatc
     1141 agatggctga tatcttgaat cagtttccat tgacctatgt caatgctatc aacagtgtgg
     1201 gcaatggttt gtatatcgat acagaacaag aagcagtagt catcaaacca aaagaagggt
     1261 tcggcggcat tggcggagag tatatcaagc cgactgcttt ggcgaatgtt cgcgcttttt
     1321 atacacgttt gaaaccagaa atccaaatca ttggtacagg tgggattcgg acaggacaag
     1381 atgcatttga acatctgcta tgtggcgcaa gcatgttaca gattggtacc gagcttcata
     1441 aagaagggcc ggaaattttt tctagaatca taaaagaatt aacgcagatt atgtcagaaa
     1501 aaggatatac gtcaattgac gaatttaaag gcaaattacg caccatttca tagcaaagag
     1561 acgaaggtca tgattgatct tcgtcttttt ttataaaaaa cactcgtctg ttcattcctg
     1621 tgcaagcgta ctcattgtat gttagacgaa cttgtgggaa aataacagag gcaaaaagga
     1681 ggataatatg aatgatgcaa cagaattagc aaaagagctt aaagaaaaag aatttagttt
     1741 tcaagaacta gttacggata tacagaaaaa aataaagaag caaaatcatg aattgaatgc
     1801 gtttgtcgcg cttgaaccat tcgagagtaa ttcccacgag ctattgattc cccagtcaga
     1861 aaaagggcca ttggctggta tcccatttcc tttaaaaatg ctcggtcaag aaaaaaaggg
     1921 atggctagct acttcaggat ctcgtttatt tgaaacacac cgagcttctc atacatctaa
     1981 ttatgtgcgg caagcagaag cgataggtct agttcctttt ggacaaacca atgcgccaga
     2041 gtttggtttc aaaaatatta cagacccagt catctatggc ccagcaagaa acccttggaa
     2101 ccttgaatgt acaccgggcg gatcaagtgg aggagctgct gctgcagttt catcaggaat
     2161 cgttccttta gctggtgcta gtgatggcgg tggttctatt agaatacccg cttcgttttg
     2221 cggattgatt gggctgaaac cttcgcgagg gacgatgcca gttggtccat atgcttggag
     2281 aggatggcaa ggagctgcta ttgatttcgg cttgacagtt tctatgagag acacggaggc
     2341 tttattttat gggatgagaa gtatccattc cggtgcgcca tatcaagtat cgccagttga
     2401 gtggcaaaca catccaagaa aaaaacggtt gaagatagct ttttgtgttg attcaccgat
     2461 ccactcacag attagtgaag aggcagtact tgctgtaaaa aaagctgtag atttccttgg
     2521 aaaagaaggg catgatttga cagagattcc ttacccacta gatggtcgta aactgatcac
     2581 gtcttattat cagatgaatg gcgcagaaac agcagcaatg atccgctcga ttgaaacagg
     2641 catccagcga gctgtcagaa aagaagaact tgaacccatt tcttggactt tgttccaata
     2701 tggtcagaag ctctctgccg ctacttacat cgattctctg catgtatggg atgaagcagc
     2761 aattgtcatg gaaaacctac atcaagaata cgatctattc ctttcaccaa cgactgcatt
     2821 taccgcccct aaaatcagcg aagatttgca aagtgatgcg ataagagcac agatggaaca
     2881 catcagtgat tgttctgaag tagaaggttt agacgttgtt tcttccatgt ttgaggagag
     2941 cttgaagatc acaccttata cacagttggc taatctgact ggacaaccag caatcagctt
     3001 gcctactcat ttgacaaaag aaaacatgcc tctaggaatc caatttatgg ctgccagagg
     3061 aagagaagat ttgctatttc aaatcggcta tctatttgaa gcaaatcatc agttccattt
     3121 accaaatcca tggaaatagc agaaacaagg agaagaagaa tgaagaaaaa aagattgttt
     3181 gctctaataa ctagtgcctt ttttatttta agcgcttgcg gtacagctgc cgctaatcag
     3241 gaagataaca gctggagtaa tgtagaaaaa aagaaagaat tagtagtagc gacttctggc
     3301 acactgtttc ccgcatctta ttataatgat caaaatgaat tagttggtta tgatgtagat
     3361 ttggcaaaag aggtggctaa acggttaaat gtcaaaatct cctttaaaga atacaacgtg
     3421 gatggacaaa tcacttctgt ttcaaaaaga gaatcagatt ttgctgcgaa cgattttggt
     3481 atcacaaaag aaagagaaaa aaaattctcc ctttcagaga ctttcaaata ttcatttgac
     3541 agtatgatcg tacgaaaaaa agatgattca ggaatccact cacttgaaga tcttaaaggg
     3601 aaaaaagcag ctggcgaacc caatactagc tatatgcgtt tagcggaaaa acacggagct
     3661 aaattagtca catatgacaa tgccacgaat gatcagtatt taagcgatgt agcaaatggt
     3721 cgaacagatg ttattctaaa tgattattat ctgcagaaaa tggccgtatc tgctttacca
     3781 gatatccctg taaaaatact ggagaacgtt tatttcaatg aaaacgaaag tggtttttta
     3841 ttgaaagaag gaaatgatgc tctgaaaaag aaaatcgatg gcgtattaaa agagatgaaa
     3901 gaagatggga cgacaaagaa aatatctgaa aaatattttc aaactgatgt ttcagtcaaa
     3961 ccgaaagaaa cgatggctga gtcggtgagt gagtgatgta ctttcctcta attgattttt
     4021 ccctcatgtg gacttcactt cctttcgtac tgcaaggctt ggtatacaca ttagggattg
     4081 gcttcgtgtc gtttctttta ggaaatctgg tagggttgct tttgacagtt ttaggtcttt
     4141 tggattggct gcctctgaat gtatttattc gtttttattt atcgttcttt agaggcattc
     4201 ccgcactagt cctgctgttt ctgttatatt ttgggttacc ttatcaatta agtgccttaa
     4261 cggcttcagt catctgcttt acgattacca gcagtgcatt tattggtgaa atctatcgag
     4321 gatcactagc aggcgtttct tcaggtcagt gggacgctgg tttagcttct ggtttttctt
     4381 tctttggggt attgaaatat atcgttttgc cgcaagcttt tcgaatctca gtaccggcac
     4441 tcagtaacgt agctatggat ctagtgaaag gtacttcgtt agcagcaaca atcacagtgc
     4501 cagaaatatt tcaaaaagca aagatcatag gcggtcggac attcgattat ttttctctct
     4561 atattttagt tgcactgatt tattgggtca tttgtatcgg gatcgaaaaa gtgcaacagt
     4621 atttagaaaa acgttctatg catcagtcaa tctgaaaaat agaaatggtg ctagcgtggc
     4681 tggcaccatt tctatttttt gtttcttgta tattctgcct agtattttaa aaccatttca
     4741 tgtaaaatgt aaatcgaaaa tatgttcgga ggtagaaaac atgaagaccc cgctaaccat
     4801 cgaaatagaa tcctcgttat accaatattg catcgagcaa ggcggcttgg ttgtagaaga
     4861 agtcacgatg cctgatgacc aaggaattgt agatacgctt agctgcttga caaaatttga
     4921 tggaagccga gaatggcgat gctatgagct gaaagtgaca aaagcagatt ttcgctctac
     4981 agccaaactg tcatttgttg gacattataa ttattttgtt ttaccaagta aactatatga
     5041 agaagtaaaa actgaaatcc ctacaggaat aggtgtttta gtgtatcgtc cgtacacggt
     5101 tgaagaggag atgcctgcct ctggtacatt tctgattgcg aaaaaagcag caaagaaaga
     5161 gcttgctgta ccggaagaag ctttgacaaa ccgcttcatg gcttctttat tcagggaagt
     5221 aagaaaagca aagcaaatgg agcgaggcgt aaaatatttt ccaacagatc aattgtacaa
     5281 agaattgaaa agacgttcag aaaatcaaga tccattttct aacgaacgat attatgaacg
     5341 gtttttagag gaaatagcta gtcaggcaat caatgagttg caagaagaag ttatcgcgct
     5401 tcagcatgat tatgaatatt tgaggcaaca acagcagatc cgtcggttgc ctacagagcc
     5461 attggagtga aaaatatgta ctatccttat ttaagaggaa aacaatttga cctattagca
     5521 ttaaaagaag cactgtcgcg aggattgctc tccaataaaa tccaaccagt gatcgaacca
     5581 gtacgtgatt ccgctacgct taaaaatgtg atcgaattat ttcaaaaaaa gcaccatcca
     5641 atcgctgtga tccaaaatcc ccaagtagga caattcaaat tattcgatca gcatgtgcac
     5701 agttggacag tcaaagaaaa tagctctgtc gtccctgcac agatcttaac gccagaaaat
     5761 ctcagtgaag tactggattc acctccagcg tttcttgttt tcgatggaca gcactaccca
     5821 aaagatacag aggtgtggaa acagttggca ggagttgatt cgaaattttt gataccagat
     5881 actagtcgct ttcgcatctg gctgcccgaa aacaaaattg tgatccgtga ctcttttcaa
     5941 acgagaaagc atgttgaaag ttatgcagat aaaacagatg acttttttag tgatgactat
     6001 ctttttttcc acgcagacgg atatattgga ttttctgatt tcacgatcga aggtagccgt
     6061 tatttcgata aagggttccc tagccgagcg cttgctatcc atctaacgta tattgatgct
     6121 tacggcaata tacgcgtgaa acattttgtc tctgacagta acgactctgc taaagaccaa
     6181 gcattgaagt ttcttgaagc aggagataaa atgaaaaaat ggatcatgcg tcaccatcat
     6241 caactcttga ttacttcagg aatgattgaa ttattggctc tttaccagca acaaaaattc
     6301 cctggactgg gagtgttgaa aaagtggtca cttatgcatc atttggaact tattagtcac
     6361 ctgctagatc atccaaaaga ttggcttaaa tattattcaa aagttcagga actatatgaa
     6421 gtgatccaat gattagataa tgtaaatgaa aaaggaatag aaaagaggaa actggatgta
     6481 tattcggcaa acaaggaaag aagaagtaga agaagtggta gaaatcatta atgccgcagc
     6541 ggatttcatt gcttcgcaag gctctcctca atggcaaaac gggcagaaac caacaaaaga
     6601 aacgattttg aacgatattg aaagaaaaga aagctatgta ttaatagtgg aagatcaaat
     6661 tgctggaaca gctgcattag tctcaagcgt ggatcccgtt tacacaaaaa tagatggtag
     6721 ttggaaagaa tcaactggtc cttatttatc gattcatcgt gtcgctttag cagaaagtac
     6781 tcgaggaaaa aaactagcaa aaccgttctt agaacatttg ttgacgattg cagccagcaa
     6841 aaatatccaa gatatccgta tcgatactta tccagctaat gaaccgatgg aaaagaccat
     6901 ctattctgct ggattcactt atcaagggat gattgaattt ccttttgaac acggcgaaag
     6961 aaaagcatat caaataatca tcaattgact ataaaatcat ctgagcaaag ataaagacat
     7021 taacactact gaaaaaaaca atcatatgat agccaagagg ttgtaacaga agtggccagc
     7081 ttcaaaaaac aagaaagaat ttccgaaaat gcttctcaaa tttttgtgga attttagcgt
     7141 attttacgaa atagctgctt tctgaaactc ccttcatcga gaggtcgtga catagctttt
     7201 gtcacgacct ctcggcttat cctacgagta ttattcgata catttatatc aataatcctt
     7261 tttttatttt atctgcagct tcttggaacg ctccatcgtt tgacacgact aaaagtgagg
     7321 ggatagcttt caaacgtttc aactgtgcta aatcttctac ataaaccgcc agtctggctg
     7381 aaatctgttc agatgaatct ccacgttttt tcaggcgcga ttgcaatgtt tctttagaga
     7441 tcgtaataaa gataggacgg actaccgtcc cgaaatactc atataaatgc caaaaaccat
     7501 ttgctgtcaa aacggcgtaa caatttccta ctgtcagttt ctttttaatt tctgctttac
     7561 tggaaccata tttatgttga gcatattggt cccactctgc aaactcattt cccttgatca
     7621 tctgattgaa tgtattgtca gaaacaaaat aataatcctc ttgatctttt tccccaggtc
     7681 ttggtgatcg attcgtgtaa gtaatgatct tttgttccgg ctgaaaaata gcttctgcga
     7741 gtgaagtttt tccagaacca gaaggaccga taaatacata gcaataattc attgtcattt
     7801 ctcctttgat gattgaacaa gtgaaaaagc tttggaaaat atttccaaag cttttaaaag
     7861 taactttgct tttttgtata ttataccagc aagccagtca caatagcact taaaaagctg
     7921 actaaagtcg ctgttagcaa aattttcaat ccgtgttttg cgacaagatt tcctttttct
     7981 tcatttaatc ccttcatcgc accagaaatg atcccgatag aagagaagtt ggcaaatgaa
     8041 acgaggaaga cagatataat tgctgttgta cgctcagtaa aatggaaatt accatttgct
     8101 aattctgtca tagcaacaaa ttcatttgta accagtttag tcgccatgat actaccggca
     8161 tccactgctt ctttccatgg gattccgctg atgaaggcaa gaggggcaaa gatgtaacct
     8221 aggatctctt ggaaagtgat gccgaatatc ccgtggaaga tagcattgat catggcaatc
     8281 aaagcaacaa aaccgataag catagcagca accgtgatcg ccacatggaa accatcaaga
     8341 atgtattctc ccaacatttg gaaaaatgtc tgttctttgt tttcttcaat gatcagctca
     8401 tcttcttttt cttctaatac atagggattt acaattgaag ccagaatata accgccaaat
     8461 aagttcaaaa caagggcagt gatcacatat ttagaatcga tcagtgccat ataagatccg
     8521 acgatcgaca tagaaactgt agacatagcc gatacactca tggtgaacaa acgtttctca
     8581 gataggaagg gtaattcctt ttttatggaa ataaaaactt ccgattgtcc taaaatagca
     8641 gaagctactc cattataaga ttccaatttg cccaacccgt tgattttact taatcctaga
     8701 ccaacagctt tcataaataa tggaagaatc ttgatatagc gtagaatacc gataatagca
     8761 gaaataaata caattggcat caatacggaa agaaagaaag gtgcacttcc tttatttgct
     8821 acaccggcaa aaacaaagtc aacaccttgc ccagcaaaag caagaagatg atcaaacatt
     8881 tttgccaata cagaaacaac cgctgtacca aaagttgtac gtaataatac gaaaccaaga
     8941 acaagctgta aaacgaacat cacaattagt ggtttcaatt tgattgcttt tttgttactg
     9001 ctgatcaaaa aagcaagccc taatgtgaca aataaaccaa taatacctaa taaataactc
     9061 aaataatcac tcctattcca aattccgttt tattttacct gttttgcaaa taaaatacta
     9121 atctttagtg aaattttcat tactttttta gagtgaaacg cattcatttt ccattagaaa
     9181 ataaagcgaa caaaataaaa ggtttaaaaa gtgtaacgtc ttagtaaagt ctataaaaaa
     9241 acgaaactat cgattaagct aatagtttcg ttttcaacat ttataagtaa actttttcta
     9301 ttggtaatat agattttcgg aagggtagac aggtgcgcag gtaatatcga ttcctagttt
     9361 tttcaatgtt tgttcatcat ttttattgac catcacagta gagtgggctt gtgctccctc
     9421 aagttcagct agtttatcat aagcaacttg agcgattgga ttcgttactg cactgattga
     9481 taaagcgatc aagacttcat tgatgcttag tgcatccaaa gaggaatgaa gtgtctttga
     9541 tttcaatcct tgtattgttt caagaactaa tggtgacaat aaaggaatgt catctgcgat
     9601 atgggctaaa tgttttactg catttaagat aactgccgct gacgcatcca tcaatgaact
     9661 tgtacgcccg gtaatgatga cttcatctgg taattcgatt gcaatcacag cagaaggatc
     9721 ttttgtagga ctttgcgctt gaatcttatc tgcatagtca tgggcaggga ctaccacgtt
     9781 tcggtcttca ggacgtaaac cgacttcttc cataatcagt ttgattcgat taactgcttc
     9841 ttcgtcgatc aatccttttt tgaagtcgca ttctgtttgg aaataacgac ggatgatttc
     9901 ttgtttagag gcttcttgga caacggtatc atccacgatc ccaaatccta cacgattcac
     9961 acccatgtca gtaggagatt gataaacaga ttctttacca gtaatttttt caataatacg
    10021 tttgattaca ggaaatgtct caacatcccg attatagttc acagctactt tattgtaggc
    10081 atcaaagtgg aaggaatcga tcatattgac atcttttaga tcgactgtgg ctgcttcata
    10141 agcaatgttc agcggatgtt tcaacggaac attccatact gggaaagttt cgaacttgga
    10201 gtaaccagct gcatgtcctt tttggctttc atgatacagt tggttcaagg aagtagcgag
    10261 ctttccactt cctgggccag gagctgtcac tacaacgatt ggtttagttg tttcaatata
    10321 ctcatttttt ccaaaaccat cttctgagac gattttttct acgttgactg gatagtcttc
    10381 gatttctgag tgtttataga ccttgatgtt tcgtctttct agtttattga taaagacttt
    10441 cgtggcaggc tgtccactat agcgagtgat aacgacactg ttgattaata agccataacc
    10501 acgtaattca tcgattaacc gcaagatatc catatcataa gtaatcccat aatcaccacg
    10561 gatcttatta cgttcaatat ctccagcata gacgcaaatc agtatttcag cttgatcttt
    10621 caatttttgc agcaatttga ttttcgcatc ttcttcaaat cctggaagta cacgtttcgc
    10681 atgcttgtcg tcaactagct tcccaccaaa ttctaaatat aatttgtcat agtggttcac
    10741 tcgttccaaa atatacgctg actgctcttc aatatatttt tctgaatcaa aaccaatttt
    10801 tttcactagg ttccctcctt aagtactaaa gcattttttc atttttttga ggattcgtca
    10861 actggaagag cgaaattcct caaaaaaaca aagaaaatgg tttaaaccaa cttgtctaga
    10921 tagttattca ttggtatgat agtttttgat aaggaaggtg ctacatgaaa aaaagacaga
    10981 aaaagaaaaa cgcatataaa cactatatcc gttcgatttt taccggttat gaaagaatgc
    11041 ttgaagatcc cgaattggaa caattgacgt ttacttatct aaacgaagaa acgcagctaa
    11101 ctcgtgatga gcatcagcgc attcatttca caacaagaga tctgcctagt aaataaaaaa
    11161 taagataaag gtcatcggat tcgattctgt cctatcagat ggaaagacta gttgatcgaa
    11221 aaaaaggctg taccaaattt tggtgcagcc tgttttatgg agcattgccc gctctttttt
    11281 ataacaattt tttacagaaa atggtactat tgaagtatta ataagtgaaa aacagatgag
    11341 taagaggagg caagtagtat gaaagagcca gatacaaatg caaattatga gccagacgaa
    11401 ctagaggaga cgaatgcgga tcaggataca ggacaagaat cgtcttcttt ttacgatatc
    11461 aaagaaaaag caagcatgaa tctttcccaa ttattagaag acttacaggc ttttgaaaaa
    11521 gctgtccgcg aagaagatat ccctgagatc taccgtttat acaatggccg attgaatgaa
    11581 gaattaaaaa gaagctcaaa tgaaaatcac gagatcgatc aattgctgat gcgtaagatc
    11641 catgatcgtt ttttacagga atttcctttt atggaacaag tagaaaacat ctcgccaacg
    11701 atgagctatt acaaaatcgg cacttattac catgatcggc ccacggtcgg tattgatgca
    11761 agtctgccag aaatttttgt tttgcctaag atcgatgaag agtgggagaa atattcccaa
    11821 ccggagtcaa cggactatga caaaaaaatc aatgagctag acgcaaaggt gatcactgct
    11881 cagacagaaa ttgaacgttt agatgaacaa ataaaagaaa tcaatcgaca aatgactgat
    11941 ttgaacgaca ataaaggatt cttgaatcgt aaaaaaatcg aggaagaaat tcaagaatta
    12001 gagaagaaga agcaagtact atctaatgaa aaattaggct ggcttcctta tattgagacg
    12061 cctgaaacaa tccagcagca aaaagaagca ttgaagcaag aagcaagagc agaccagctt
    12121 cgtgcagcca tcgtagaaaa agaacaaagg caaatcagac gctatttcgg tagcaaagag
    12181 ggattcggtc aagcaatcca tgaattcttg atgaattatc ttggcaatga gaatcctaat
    12241 aatcaatcta atgaaggagg ttccgagtat gaatgaacac gatgaagcag aatggacaaa
    12301 aaatgaagaa caaacagaag atcatgaaga aacgaacact tcattggaag aacaaacaag
    12361 taatcctctg gatgacacag aagaaatccc tatgctagag gaaacaaaaa tacacgaaaa
    12421 agaaaaagta actccgacga atacgaatac tgcagaaaac acccatgctt acgaaataac
    12481 tgaaaatccc gggtatttag aaggaaaaga gcaagatcat caagatatcg tcagtttgat
    12541 tgaaacagcg gaagcagaat tagcggattt acgtatgaga aaagatttga tcgaatcaga
    12601 ttttccacaa ttattagaat catatgatcg ttttatattg aatgaagaac caatctccac
    12661 gatcggaaag acaagcctga tcgaatactt cacgtatgaa ttactgaaac cgttgaatga
    12721 tattggtctg gaacggtcaa attcagctta tgacacatgg aaaacaagac atttttcgat
    12781 caattatacg ttgaatggac aaaacgaatt agtcttttcc tttgtattac cgaccatcga
    12841 tcaacgatac caagtggaat cgatgagtct cctaaacgta tcaccagaga caatggaaat
    12901 caatgtccaa gatgaccggg tgctttcttt gatccgacac tggtcagtgg atcgagtatt
    12961 ctctgcaggg cagatcacga tattcaatca caaattgaat caattattag cccatgcaag
    13021 aacacttggt tttaccgtta atcagacatt actagacaat acgaagccac ttcgtttgaa
    13081 tcttcagagc gaatttgaat tgacgaatga agtattggat gatattttta tcgtggcaat
    13141 gaaaaatcca tcctacgata tggaaaagat caacgaaact acttatcaag tacgattaga
    13201 taaaggacag tctttaacga taacaacaaa cgaaaaagat caaacagtct tgtcgatctc
    13261 atctggagac tacccacgat ctgtcattga tttctttatc aattacgaat tcttggtccc
    13321 attaatggtg agaaagtcct gattggataa gttggattac cagatgtcat tcagataatt
    13381 ctgttccaaa ggacttgcgg cagttatcca gaataattgt cacaagtctt ttctgtatgt
    13441 actaaatgga cgtgaataac ttgctgatga aggagggatt tcattaggaa tgtccacaaa
    13501 taaaatagca cagcttagct tattgtctgc tgcttgtgta gcaggtagga tcgcttttca
    13561 atttattccg aatttccagc caatgactgc tattttttta tttatagtac tttacttaag
    13621 cttaaaagat gcgttaattg tcatgagtct ttctattgcg atcagcagtt tttattttgg
    13681 tgttggacca tgggtcatcg gccaatggat cagctatact gttgttctga gtttgttttc
    13741 aatcgtctgc ttgagaaaaa cagtgcaaag gaatctatgg ttaaagggag tctgtttttt
    13801 tctggcgggc atggtttacg gaataggtat gaccgttttt gatacgctgt tatatcgttt
    13861 gcctcaacct tggatctatt accttcaagg ggtgtcgttt gatttgatgc acagtatagg
    13921 caatgttgtg ttctttcttg tttttctgcc agtcgtcaaa cgtttttaca atcattcagg
    13981 aggaaaaaat gaaaaaaata atttatagtt tgcttgcaat gagtgtcagt atactcattt
    14041 tgacaagttg cagtacaacc tatacacaat cggcttccaa ccaaaaggag gaagtaaaaa
    14101 catcgcaaaa agcaacaatc acgttacaag aaaatggtca aaacttttcg gaaaaagaag
    14161 tgttcttcaa aaaaggcgat gatttactga gtattttgaa acgaaatttt gaagtcaaag
    14221 aagataacgg cttcatcact tcgcttgaag ggcactcaca ggatgagaaa aatcaactct
    14281 attggatgtt tactgtggac gggaaaagtg ctactactgg tgccaaagag atcaaattga
    14341 atgatggaca atcggtcatt ttcaatttgt ctaaactata agtttcataa aaaactgtta
    14401 aagggcgaat attgccataa ttcagtgagt tcagttgatg aaagaaggaa aataacatgg
    14461 aaaattttaa aaaaagcgga atgttttccg taattgctgc tctaggggct aatattctag
    14521 ttgctatcag caaatttgtc ggctatgcaa tcagtggcag tgccgccatg ctaaacgaaa
    14581 gcatccacag tatcgttgat tgcagcaatc agattttgct gttattcggt gataaacaag
    14641 ccaataaagg acagagcgag ttgcatcaat ttggtgaagg acgagcaaaa tactttttca
    14701 gtacaatcgt cgcaatgatg cttttcttcg gcggtggggc acttggggtg atggaagctt
    14761 ttgaaaagtt gacgcatcca tcccatgaag tgggtaatcc gatcattgtt atagcaatac
    14821 tgttatttgg tttggtaatc gaaggaagtt cgttacgcgt ggcaatgaaa gaaatcaaag
    14881 aattgaatac tgaaaaactt tccacgatgc gctttttgcg cgaaagtcga cacagtgaaa
    14941 tactgattat ttttacggaa gacttgtgtg ctgtaatcgg tttggtcttg gctttagcag
    15001 gaacaatatt gacttatgca accgggattg ctgcatttga tgcgatcagc ggattgctga
    15061 tcggtttctt gctgatggga gccgccattt tcctagcaaa agaattttat agtctgatca
    15121 tcggtgaaag cgtgacagca agcgatttat caaaaatcaa gttagctttt gaacgtcctg
    15181 agatcagtcg gctgatcgat ataaaaacag ttcatttaag tccaacggag attttagttg
    15241 cagcaaaagc agatatcgtt ggtaacaaag agaatgaagc ttactcggtc atcaatgata
    15301 ttgaaaaaaa tatgcgtcag tctcttcctg acaagaagat gtatatatac attgaaacag
    15361 ataaatatga cccaaattat tctcgtaaat aaaacgttta ttcatgaatt gaagcaaaaa
    15421 tgagaaaaat ataatcttgt ttttaaataa aacggctaca atttagcgaa tttatgttac
    15481 aatgagtccg ctgtttattt gttgtaatta aaggagatat tttaatgaac aaaaagaaaa
    15541 gtgcgccatg gcttcaagct ttgcatgcag tgatgccact ttgtataagc tatataccag
    15601 taggattagc ttgcggagta ttgttgcaaa aagttggatt tgatcctctc ttatcaggac
    15661 tgttatcgat tctggtcttt tccggtggcg cgcagttttt agttgcatct atgcttacga
    15721 cgcaagcatc atttgcaacg acattattga tggttttctt tttagaatta cgctatacat
    15781 tattaggagc aagtcttgcc ggttttatga aaaaagaaaa gcggacgttt ttggctgtct
    15841 tttctcaatc actgaatgat gaaaactatg cggtgaacta cttaaagttt tcaactgacc
    15901 cttcctggaa taaaagaaag gctttatatg tcaattggtt ctcaatgact gcatgggccg
    15961 gtagcaatat gatcggtaat tttttcggct cggtgattcg agtagatgct gaccttgtcc
    16021 attttgcttt gacggccatg ttcattttca tgtttatcat gcagatgaaa agcgcactac
    16081 tgatctttac aggtttattc tcaggcgtat taggggtcgt attcatggta ttattccaaa
    16141 atactttcgg attgattgca gcaacagtca ttgcttcatt tgccggattt atgctggaga
    16201 aggcattcaa aaaagaaaaa gctaagaaac taagagaccg cggtaaagat gtcaatgagc
    16261 cgctcttcaa cttcccggaa caggaggcca atcaccatga ctaaactata tttgctactt
    16321 ttagttgctt gtctgttcat cgtggcatat atcccgcgct tgttcccgat gctttatttt
    16381 actcatcgaa aagtgccatc ctggttcagt gactggatga aatatgtacc ggtggcatta
    16441 tttgcggcgt tagcttttaa agatgttttc attactcatg aacatctgga tattgcttgg
    16501 aatatcaaaa tagctgcaat gattctagta gcaggcgtgg cttacaaaac acgttcgatg
    16561 gcgttgtcag ttttgacagg acttgcgtct gtctttttgc tgtctatgct ttaaactgtt
    16621 ttattttatt aaaaacagag attgcgacat aagttgttca aactgatcta tccgaactgc
    16681 atttgcaaca gtcaattctg gatgcaagtt tattcgtagg gataaaaaag attagtgttg
    16741 gcttatgatg caagctcttt tttattttag gaattagaga gggatttgtc cttctatgat
    16801 tttttgctat aatagggaag atgtttattt tatgaaagaa tagttgaggg aatttaaatg
    16861 aataaaaaat tgatgcaagg aacattttgg ctaacctttg ctaatcttct atgtaaagtt
    16921 ttaggggtag tctatttgat tccctggcta agtatgatgg ggaacaatca agatggtatg
    16981 cttgctacga cattgtataa tgttggctat cttccttatg gattgttcct gatgcttggt
    17041 acagtcggat ttccaaatgc gattgcaaaa aaagtagctg tagccacaaa agaaggagat
    17101 aacgctgctt gtcggctgat ttttagaagt acgatcaata tcatgtttgt catcggtatc
    17161 gcctctgctg cactgatgta tttatttgct cctttactag ccggaatcag tccgattgct
    17221 aacgttaata atgggatact agctatcaga agtttatgcc catctttgat tgctatccca
    17281 attcttagtg caatgagagg atatttccaa ggaaaaaatg atctgcggcc ttatggaact
    17341 tctttgatta tcgaacaggc tgtgcgagtg atcgttatct tggctggtac ttattacttg
    17401 cgcgtattga ctgacggaac catattagaa gctgtattga tcagtacagt cgcttctttc
    17461 ttcggtgggt tagctgcgat tatccatatg tatatcgtcg gacgcagaaa agacttcttc
    17521 gaacttaaag attttttgat ttccagccgt tatttcgaaa gagaaaaccg atctgcctct
    17581 gtctctatca ttcgggaaac actaccgttt atttttgtcg gctcagtcat tactatcgtt
    17641 caaatgatcg accaagtaac gatgaaacca ctgcttcact ttttccgtcc agagatcgca
    17701 gatcagcaac tggaattctt attcagccgt gcttctgtca atccaaataa attgacattg
    17761 atcctgatct ccatggtagg aacagtagct ataagcagct tgccaatatt aagcacgatg
    17821 aagaaaaaag atcggataca aatcgaaaaa acagtaggag atagtttttc gattgcgtta
    17881 ttgattcttc ttccttcatt gactggaatg tctttattag ctggaccact atacacattg
    17941 ttttttggct atgatcctga aagtgtcgga tatttccaaa tggctttgct agcttctttg
    18001 tttttctctt tattcacgat cctatctacg atgcttcaat ctttgaatca ccatcgtttt
    18061 gcgatccgat taactgtaga agcaattatc ctgaaagtca tcttccaagt aatcggatta
    18121 ggattagttg gcggatacgg gatgagctta tcaaatggct tagcattcgg tattgtcttt
    18181 gttcgcggct atcactttat gtgcaaagaa taccgaatag cacctttagc aaagatcagc
    18241 aattttttct taaaaacttt ccgctccacc ctgattatgc ttgcagtatg ttttgccgtt
    18301 ttctttttgc tgaatcagcg attgtcaatg gaatcaaaaa gctatgcaat gatttattgt
    18361 gtggctgtag gaagtattgg cggcttagta tttttatttt ctcaattcgg aaaaaatggg
    18421 tttcgaatgt tgaaaaatgt taaacatcat agcagaagca aagaataggt taactaatcg
    18481 ttttttgctg tcacttgaaa aacggcaact cgtatgatta cgcttgtcgt ttttctattt
    18541 tccaatttta gtttcatatc taatcttact tatgatatag ttataaggtc tggaaaaatt
    18601 ctttgaaacg aggaaattaa acacatgaaa cttgcagtag ttacagatag ttcggcatat
    18661 ctgccggaac gtatcaagaa ccatcccgac ttattcgtta ttccaatccc tttgattatg
    18721 gatgggaaaa tttataacga aggaatcgat atcgaagcgg atgaatatta tggactttta
    18781 aaaaacagta aagattttcc tactacttca caacctgtcg taggggaagt tttgggttta
    18841 tatgaggaat tgaaagagaa agggtatgac acgattttaa gtatccatct ttcttcaggg
    18901 atttctggct ttgtcaacac attatttgcg atgaaagatg acatcagcgg agtaacggtc
    18961 attccttatg actctaagat cactagtatg ccgatgggac acatggtaga agctgcctta
    19021 gacttaaatg atgaaggtca gtcccttgat gaaatacttg cacatatcga tcgaatccga
    19081 gataatacct acgcttatct gattgtagat gatttgaaca atttagtacg aggaggacgt
    19141 ttgacaaatg gtgcagcgct gattggcagc ttattaaaaa tcaaaccgat cctgacattt
    19201 tctgaaggga aaattgtttt attcgaaaaa atccgttcaa gtaaaaaagc atttgctcga
    19261 gctgaagaaa ttattggtag aagaaataac gaaatacaac cgccagtcaa actttacgtg
    19321 atacatgcaa ataatttaga agtagcgatt gcggagaaag agaaattgca gaaaaaatat
    19381 ccaaatgcag aaatcgaaat tggtcatttc ggaccagtca ttggtacaca tttaggtgaa
    19441 aaagccatcg gcattgccat ttcagcgcaa taattccttt tattcaaaaa acataccaaa
    19501 aatattccaa catcatcttg gactttctac atgttactaa tgagcgtgta aaagaacgag
    19561 atggtgtttt tatttctatc aatgaagctc tttttctttg caatcctcac ttcaatcctc
    19621 tataatgtcg catatagttt agtaaatgag taaactacta atttacttat ttactaaaaa
    19681 taaaaggatg aggagttaaa ataatggaaa taccaacaaa tttaaaacat aaaccagtaa
    19741 tcgttgtaga agactatgat aaagttgatg gaagaaatgc attaaatacg gatgcaaaag
    19801 ggctttcact gggccttgct cagtggaatg atcgtggaaa agtcgatatc tcaggcaagg
    19861 tatggcgaca tactggagaa aaatggtcac gacagtcgga agaattacca atcacacgta
    19921 ttttagattt agcgatctta gctgcacaag gaagtttata cttccaagat gcttatcgtt
    19981 atgaaaaatt ttatgatcca gaaaatccag tcgtagacat cattggatta caagggaacc
    20041 gaatgacggt agaagtagat accaaaaatc caaagatcga tgaagacatc attttgtatt
    20101 acgatacact acaaaaagac ggagaactga ttggggaacg attccgtatt ttaaaacgtc
    20161 ttttagatga gctaggatat taatagacag agatgatcaa aaggggaaga gaagcatgga
    20221 gaatttctca ctaacagaaa accgaacctt ttcacggcta gaaaagcaaa tgatctggaa
    20281 gaaaccgaaa agccatcgga caagtgcaga agaatggcgg atcgcctccg aaatcaaagg
    20341 gaattggcaa gatcctgaaa tgaaaatcag taacgtactt ttggaaggag atgccgggtc
    20401 ggggaagaca caattagcca aagcactatc tgctgatctg caacttccct atacaaaagt
    20461 gacctgtttt gcagatatgg acaaatcaga tgttttcgga gccttattac ctgtagtaga
    20521 ttctaataag gaacaagacc aagaattact agaagctatt taccaaacag atacacttga
    20581 agctgtactg acactgatcc agaaccatta cggcattgat cctttttctg ctaaagaaaa
    20641 attagcagag ctagttcaaa ggatcgaagc tgattatcca gatgcaatcc attacagcta
    20701 ttacccttct gaaatcgttc gagcgattga aaaaggatat ttattagaga ttcaagagcc
    20761 gactgtcatc cgagatgcct ctgttcttgt ggcacttaac tcagcgctcg aaccaaatgg
    20821 gatgttgaat ttaccgacag gaatcattcg tcgccatcca gattgcgtca ttgtgatcac
    20881 tacaaatcga aattaccaag gaaatcgccc attaaatgaa tctttaagag atcggatgca
    20941 acatgcggaa aaaatggatc ttcctgcctt agaagtcatg gcagaacgtg cgatggcgaa
    21001 aactatgatc caaaaacaag aacttctctt aaagatggca gagattatcc gtttgttgga
    21061 tgaaactgca aaagctaacg ccatcaaagg tgtagcagga atgcgttctt atttttattg
    21121 ggcaaatacc tataagcaag gacaagattt actccagtcg atttatccaa aagttttgta
    21181 taaattatcc actgattcag atgaattggc aattcttgaa caagctttgt ctgacagtgg
    21241 attgctactg gaacttcagg acatattgag aaaagaaaaa tggggtcatc ctcaatctga
    21301 gcatacaaaa ggaagaacca ttagcgccga agaagcaaat gaacgaaaca tcactgaaaa
    21361 tgctgaagaa attctgcgct tagatgaaaa gaaatcgttg tctgctgaag aaccaaatga
    21421 gggagaagag aaacaagaag aaacaataga aaaaaacgag attcctcctc aaatgcaaaa
    21481 agaacgcagt agcgatatcg aaggaaaaaa tcaaaaagaa caacaaacag gagatgattc
    21541 tcaagaaatg tctgcttctg acatggaagc acatgataag gaaatcaaga agcaactgaa
    21601 taaagaagcg cgacaaatca tgaaggaaac gattcatgaa aaagaaggtc tcatcgttca
    21661 ccgaccagct ttccaaggaa aaacgccgga agcacgtgag ctacacatgc aagtaatgcc
    21721 aatagtagaa tcacttagcc ggcaaatttt agagttactg gataatgaac aaacagagac
    21781 gtaccaaaaa ggaaaatacg aaggtcagcg gttcaatgca agcaaagtag catatggtga
    21841 tttgagaaat tttgacaaaa agaacccgcc acatgagcaa ccttctttag cggtagctgt
    21901 acggatcgat gaatctgggt caatgatacg ggatgatcgg atcgaagcgg caaaaaaagc
    21961 agcgattgcc attgccgaat tttctaagaa agtcgatatc ccattgttga tttacggaga
    22021 tacagcagac cgttcgtcaa gagaaaagac ttctttgttt tcttataaag aatttgaaga
    22081 cggatttcaa tggttaaatg aaaaattagt cactatgaaa ccaaggcaaa acaatcgtga
    22141 tggtgctgca cttcgtttag cagcagaaaa attaaacaga caatccgcaa caaccaaact
    22201 gttgcttaat attagtgacg gtcagccaaa agcgttgccg gattatacag gcaaaaaagc
    22261 aaaagaagat atccagtctg ttttgaaaga atatgaacgt caaggaatcc tatttgtctc
    22321 cgcagctatt ggccaagaca aagaagaaat caagtcgatc tacggtgaaa gtcgttttgt
    22381 agatattact gacttgaatg aatttcccaa gcaaatgatt caactgattg cccgctatct
    22441 atgataaaat aaagctcaac gaacgcactt agcagattcg ttgagctttt cgtttctagt
    22501 taccggtaac aaggatactt ctaaaataga atcggttata atcaagaggg accgttaaag
    22561 gagtgaaacg atatgataca agaacaaaaa tggtggaaag aagcagtagg ctatcaaatc
    22621 tatcctgcta gtttcaaaga tagcaatggc gatggtcaag gagacatcaa tgggatccgt
    22681 gaaaaactta attatttgaa agatcttggt atcggcttta tctggatcaa tccgatctat
    22741 caatctccat ttgtcgataa tggttatgac gtaagtgact atcaagatat agaagagaga
    22801 ttcggaacga tggaagattt tgatttattg ctaaaagaag cacatgaatt agggatcaaa
    22861 gtgattatgg atcttgtcat caaccatagt tcggatcagc atcaatggtt tgaagaatcg
    22921 aaaaaatcta aagaaagccc gtatcgcgat tattacattt gggtcgacgg ggtagatggc
    22981 aaagaaccga ataattggac atcgattttc ggcggttctg cttgggagta ttctcatgaa
    23041 actggacagt attatctgca tgtttttgca aaagaacaac cagacttaaa ttgggaaagc
    23101 gagaaattga aagaagaact attcaatatg atccgatggt ggttggataa agggatagat
    23161 ggatttcgtt tagatgcgat ttctcatgta aaaaaagatg aatattcagt aaaagccaca
    23221 gagaaccctt tctcaccctt tcaaaatgtc tcaggaatcg aagaacattt gaccgatttg
    23281 aaacatgttt ttgaagagta cgatatcatg actgtcggag aagcaagtgg tgtcactgca
    23341 gaagaaggac cacaatgggt agggaaagac ggttatttcg atatgatatt cgaatttgat
    23401 catatccata tctggcagca agaaaaagaa gggcaattag atgtccttaa attgaaactt
    23461 gcattaagcg cttggcaaac ttcattggat ggtatcggat ggaacgcttt atatatggaa
    23521 aaccatgatg ttcctcgtgc cgtttcagtg tttggagata ctcgtcccga tttttgggct
    23581 atgtctgcaa aagcaatcgc tatgatgtat ttctttttgc aaggtacgcc atttatttat
    23641 caaggacagg aaatcggaat gacgaatatg ccctttgaat cgatcgatca agttgatgca
    23701 gtagattcga aaagacttta taaaaggctg cttgcggaag gtaagacaag agaagaagca
    23761 ttggatatca ttcgtgaaac aacgagagac aacagcagga cacccatgca atggacttcg
    23821 gaacaatatg ctggtttttc tacacatgaa ccttggctga tcactaatcc aaataccaaa
    23881 acgatcaatg tagaacaaca agaatatgaa ccagagtcgg tcctgcaatt ctataagaac
    23941 atgatccgca ttagacaaac caataaaggt ctgatatacg gttcttataa agaatatctt
    24001 catgaacatc cacaacttta tgtctatgaa agatatttag aagatgaaca atatcttatt
    24061 atggtaaact taacagaatc acttgctgac tatgaacttc caaaagaagc agatcagtcc
    24121 tggacattac tcttgtcaaa ttcctctagc ggagaatttg aagctaaagg catactagca
    24181 ccttatgaag ctcggttata taaaacaaac aagtaaaact tcctcgttaa agttcattag
    24241 ttggactttg cgaggaagtt tttcagattg ctctgtcaat tactcatttc aataattcgc
    24301 tctaggacca ccgatatatt taggacgaga gcgaagggct gtcacgtgag cttgtccaag
    24361 ggttttcaaa cgaggtctga caggtacttg gacatgtttg atatgcatac cgattgatgt
    24421 gtcaccgata tcgataccgg cttgtccaac tacgtgttcc acttcgacag gatcattgaa
    24481 ctggtcaaaa gcagcaacag aacaagcacc tccagcatgt agtgcaggaa caacagagac
    24541 aatttcgaaa ttttttgctt ctgccactgt tcgttctact actaatgctc ggttcaaatg
    24601 ttcacaacct tggacagcta gcgcaatttc tttaggatcc aacaactctt ttaacgtacg
    24661 gatgatccat tgaccaactt ccgcactgga attttttcca atatgtcctc caacgacttc
    24721 gcttgtgctg catcctaaaa caaaaagatc accttttttc aagtgtgcct cagccaatat
    24781 gtcattaact atttcagtca attggtcttt taattctttt tctgacaact tcattttcta
    24841 aaaccttctt tttcaattaa tattgcttcc gtgcttgaat acgttgaaga cttgcagtta
    24901 taggaaaggc aagtcccatt ccaatcagat tttggaagat gtttcctggt atagaagcca
    24961 ctccagccgg ccaatcatat aaaatccaac cggcgatacc atagccgatg atcataacta
    25021 agcttcctaa taaaagccct aatccccaca tacgagtaga agatttgctg aaagaaccag
    25081 caacatatcc ttgtaacccg tggatcacta atgaaaaaac tgcccactgc ggatatcctg
    25141 aaatcaaatc gatcaataga ccactggaag caccaacaac taatccaccc gttggaccat
    25201 aaagaaaagc agcggtatag atcccggcct cgcataatgt cacaaatcca ttcgtagccg
    25261 gtacagggat caaaattgtt aatgaaaggg caactgtcaa cgcaatcagc atagcataga
    25321 tcgttaattg cttagttttc atttctcatt cctccttttt gaataccgcc agaccagaca
    25381 cttccggtat gatcgttcat cagcacgcca ttagaaatac aatgggcaac aaatttttta
    25441 ctttctgcta ctgctttggt aaaatctgcc cctaacacaa gattcgctgt tattgcagaa
    25501 gaaaaggcac aaccggcccc gtttactgtt gtagtgtcga tttttttatg agaaaatacc
    25561 tcataatgat caattgaata gagaagatcc acagcttcat ctccagccat ccttgtgccg
    25621 cctttgatca caatgttttt tgttcctgaa gcagtgagtt ctttagcgag atggatcatt
    25681 tctgttaacg aagagggaag agcttgacca gaaagtaaag cagcttctgc caaattaggc
    25741 gtaatcatcg taacaagtgg aaaaagttct tcgatgagct gcgaaatata caattgattg
    25801 atcacagctt cagtttcttt gaatgccaaa acagggtcta aaatgattgg gatattttgt
    25861 tttgttttta tgaagtctcg aacaaccatg attgcttcac ttgaattcaa taacccaatt
    25921 ttgataccat ctaatgaagt cattttatca atcgaaacta actgtcgttt aagcaattcc
    25981 aaagatatag attccagcat aaatcgctca ttaatatcta gtgcccctat agaagtcaag
    26041 gcgcttagtc cgaatagacc aaaattctca aaagttttta aatctgtttg gattcctcca
    26101 ccagcaaatg gatcagaacc gccaattgtc aagattcttt tcataacatt ttcctccatg
    26161 aataagagta taacgaaatt ttcaaaaaag aaaaacagcc aattggcata tttttatctc
    26221 atccaattta aaaaaacaaa aagaaaagaa agaccaaaat ggatctttct ttccttaaat
    26281 agttaggact tttgtgattt taattctttc tcgatttgaa gccgttgcac tttcattgta
    26341 gctgttcgcg ggattgcatc aaaatcacgg atgataggga cgttcaagcg aggaagttca
    26401 tggacttgct cccaccatcg attccaatcc atttctttat caggagctaa agcaataatc
    26461 ggttgtggag aatgattttt atcccttaca atcactactt ctgccaaaaa atctaacgaa
    26521 tctaataaaa agtcttcaat agctaatgta ctattgatcg tttcgatcaa atccacttgc
    26581 cgatctttca aaaataggtg gccatgctta tccataaaac cgtaatctcc gctatcccac
    26641 caatcgccat aaacattttc ctggaaccgt gcatcttcct tgtaataagt caaagcccgt
    26701 cctttagaca gtaattgtat atgaccatct gtgttttcag gtaggacatt cccaactgaa
    26761 tctgtaatcc gagcgcttgt catgtcttcc agtccaacgc ccatatctct tgcatcactt
    26821 gttttcaaac tctctagtgt atgagcctta agaatcattg gtccgcattc actttggcca
    26881 tatacttgaa gaaataccgc atcctgtgcc atcgacgttc gcaaaaatgt cttcattgtc
    26941 tggttgttta tagcatcaaa agtggagtga tagtatcgga tacccgaaaa agcttctgga
    27001 tgctccttag cagtaaaacg ccactgaaca aagttattcg gatgggtctc tagtgcaatt
    27061 ggccggtgag cttccaacat atgaacaact tttgaacttt gtgcgtttgc taaaggcatc
    27121 ataggaaatc ccatggacat caaagaagag ataccaatat tgaatctgga atgcactgga
    27181 gagatgtgaa aagcgattaa tttcttttcc gaaatttttg tgaaaactgt tttttgccat
    27241 ttcgtccgcc atcccataga atgagcagaa tgacaaataa gtttagggat accagttgta
    27301 ccagaagtat gggtcatata agaaatttca tttttgtcta aaaatgattg agaaacagac
    27361 aaagcaggtt gttccattaa ataaagaata gg
//
LOCUS       DACBYO010000031        26158 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.031, whole genome shotgun sequence.
ACCESSION   DACBYO010000031 DACBYO010000000
VERSION     DACBYO010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.031"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(62..1093)
                     /gene="queA"
                     /locus_tag="IVD26_001297"
     CDS             complement(62..1093)
                     /gene="queA"
                     /locus_tag="IVD26_001297"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAP6079284.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1286..2461
                     /locus_tag="IVD26_001298"
     CDS             1286..2461
                     /locus_tag="IVD26_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP6079285.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2465..3106
                     /locus_tag="IVD26_001299"
     CDS             2465..3106
                     /locus_tag="IVD26_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079286.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3103..4020
                     /locus_tag="IVD26_001300"
     CDS             3103..4020
                     /locus_tag="IVD26_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6079287.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4017..4688
                     /locus_tag="IVD26_001301"
     CDS             4017..4688
                     /locus_tag="IVD26_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079288.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5229..5717)
                     /locus_tag="IVD26_001302"
     CDS             complement(5229..5717)
                     /locus_tag="IVD26_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAP6079289.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5918..6184)
                     /locus_tag="IVD26_001303"
     CDS             complement(5918..6184)
                     /locus_tag="IVD26_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP6079290.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6184..6447)
                     /locus_tag="IVD26_001304"
     CDS             complement(6184..6447)
                     /locus_tag="IVD26_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP6079291.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(6440..6712)
                     /locus_tag="IVD26_001305"
     CDS             complement(6440..6712)
                     /locus_tag="IVD26_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079292.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            6923..7108
                     /locus_tag="IVD26_001306"
     CDS             6923..7108
                     /locus_tag="IVD26_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6079293.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(7250..9073)
                     /locus_tag="IVD26_001307"
     CDS             complement(7250..9073)
                     /locus_tag="IVD26_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAP6079294.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9671..12376)
                     /locus_tag="IVD26_001308"
     CDS             complement(9671..12376)
                     /locus_tag="IVD26_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAP6079295.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12682..13629)
                     /locus_tag="IVD26_001309"
     CDS             complement(12682..13629)
                     /locus_tag="IVD26_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAP6079296.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13819..14088
                     /gene="rpsN"
                     /locus_tag="IVD26_001310"
     CDS             13819..14088
                     /gene="rpsN"
                     /locus_tag="IVD26_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAP6079297.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14264..14626)
                     /locus_tag="IVD26_001311"
     CDS             complement(14264..14626)
                     /locus_tag="IVD26_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP6079298.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14637..15758)
                     /locus_tag="IVD26_001312"
     CDS             complement(14637..15758)
                     /locus_tag="IVD26_001312"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAP6079299.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15774..16124)
                     /locus_tag="IVD26_001313"
     CDS             complement(15774..16124)
                     /locus_tag="IVD26_001313"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAP6079300.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16254..17765)
                     /locus_tag="IVD26_001314"
     CDS             complement(16254..17765)
                     /locus_tag="IVD26_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP6079301.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18087..19439)
                     /locus_tag="IVD26_001315"
     CDS             complement(18087..19439)
                     /locus_tag="IVD26_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAP6079302.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19592..20668)
                     /locus_tag="IVD26_001316"
     CDS             complement(19592..20668)
                     /locus_tag="IVD26_001316"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAP6079303.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20864..22609
                     /locus_tag="IVD26_001317"
     CDS             20864..22609
                     /locus_tag="IVD26_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAP6079304.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22889..23326)
                     /locus_tag="IVD26_001318"
     CDS             complement(22889..23326)
                     /locus_tag="IVD26_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAP6079305.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23310..24683)
                     /locus_tag="IVD26_001319"
     CDS             complement(23310..24683)
                     /locus_tag="IVD26_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079306.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25005..25493)
                     /locus_tag="IVD26_001320"
     CDS             complement(25005..25493)
                     /locus_tag="IVD26_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6079307.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25515..26117)
                     /locus_tag="IVD26_001321"
     CDS             complement(25515..26117)
                     /locus_tag="IVD26_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP6079308.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7503 a         5560 c         4838 g         8257 t
ORIGIN      
        1 ctttgtcata aaatctttgt aaagcttttt tgttattcaa aactagcggc ttttcataac
       61 cttatttcac gaacatcgca tctccaaaac taaagaaacg atagcgctct tcaatcgcat
      121 gctggtaagc agataaagtc aattctcttc ctgcaaaggc actaactaac atgactaaag
      181 tcgattttgg caaatggaaa ttagttgaga aagcttctac cactttgaat tcatagccag
      241 gcgtaatgaa aatatcagtc catccgctgt ctgctttgat ttctccatta aatttcgttc
      301 caatcgtttc taatgttcga attgaagttg ttccgacagc cacgattttc ccgccatttt
      361 tacgtacttg gttcaatcgc tcagccgctt cttccgtcaa acggtagaat tcactatgca
      421 tatggtgttc ttcaatttta tctacgctga caggtcggaa tgtacctaac cctacatgta
      481 gtgtcagata gactaattca acaccctttg cttcgatctc atcaagtaat tctttcgtaa
      541 aatgcaatcc agctgttggc gctgcagcag aaccattttc tttcgcatag acagtttgat
      601 agcgatctgg gtcttccaga cgttctttga tatatggagg caatggcatt tctcccaatg
      661 attcaagaat ctctagaaaa attccttcat actcaaagtc aatgatccgt ccgccgtgtt
      721 ccaattcttc tttcactact gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa
      781 ctttggcacg tttcgcaggt ttgatcaatg tctcccacgt atctccttgt gtattcgtta
      841 gaagaaggac ttctaaatgc gcaccagtat ctggtttttc tccatataaa cgagcaggca
      901 gaactcgtgt attattcata actagcgcat caccaggctg taactcttca atgatttcat
      961 ggaaatgttt atcttccatc tctccagttt tccgatccaa aacaagtaaa cgagaatgat
     1021 cgcggtcttt taatggtgtt tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt
     1081 ctgttgttaa catatcgtca ctcactttct atcatgtgct tcatcattct atcatgtttt
     1141 tcgttctgtt ggcaaaatca gcactttttc acttctattt tttgttttcc taaataaaaa
     1201 aactacccta tttgtatttt ttcattgttt taggcatact agtaatagat agttcttcat
     1261 tgaaaataga aaaagaggtg gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa
     1321 aggtggaaaa gtcgctgtag aggacgtcaa tctttcattt gaaaagggtg agttcatttg
     1381 ttttatcggt acgagcggaa gcggaaaaac gacgacgatg cggatgatca accgaatgac
     1441 tgatccaaca caagggaaaa ttttgattga tggaaaatcc atccaagaaa ttgatccagt
     1501 ggaattgcga cgtcagatcg gctatgttat ccaaagtatt ggattgatgc ctcacatgac
     1561 gatccgtgaa aatatcactc ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa
     1621 taaaacagct gaaaaaatga ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta
     1681 cccacatgaa ttatctggtg gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc
     1741 gaatcaagat atcatcttga tggacgagcc attcggtgcg cttgatccaa tcactcgtga
     1801 ttccttgcaa gaccttgtca aagatttaca agagcgtttg ggaaaaacga tcgtatttgt
     1861 aacccatgac atggatgaag cgattaaact agcaagccgt atcgccatca tgagtgaagg
     1921 ccgtgtgatc caatttgata caccagaaaa tattttacgt catcctgcaa acgatttcgt
     1981 agaagagttg attggagaag atcgcctact acaagccaag ccaaatgcga caagagtcgg
     2041 cgaagttatg ctaaatacag caatcacgat tacaccggaa aaatcattac aagaagcaat
     2101 caaactgatg agggaaaaac gtgtagatac gttgttagtt accgataatt cgaatgtatt
     2161 aaaaggattt atcgatgtag aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg
     2221 cgacattttg aataaacatg ttttttacgt aaaagaatcc gcctatcttc gtgatacctt
     2281 gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc gttgatgaac agaacaaagt
     2341 cgtaggtatc ctgactcgtg catcattagt ggatatcgtc tacgatgtga tttggggaga
     2401 agatcccgca actactgatg ttgcagagtc agctactcct gaagaatcta aggaggtctg
     2461 acctatgcag cagttttttc atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca
     2521 tctttatatt tcaggacttg ctttgatcat tggtatcatc attgctgtac cgcttggtgt
     2581 cttactgaca cgttttccaa aagctgccac gattgtgatt ggcttaacca gtgccttgca
     2641 gacaatccct tctcttgctt tattggcatt gatgatcccg ctatttggcg taggtaaatt
     2701 acctgcgatt atcgcactct ttatttattc attattgccg attttacgta atacgtacat
     2761 tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca aaaggcatgg ggatgactga
     2821 gttccaatcc attttttccg ttgaattgcc cattgctatg ccaacgatca tggctggtat
     2881 tcgtttagct gccgtttacg tgattgcatg ggctacactt gcctcttata tcggcgctgg
     2941 tggtttaggc gatttgattt ttagtggact gaataattac caaccagatc tcattttggc
     3001 aggtacgatc cctgtaacaa ttttagcact attggctgat tggcttctag gtctcttgga
     3061 acaccggctg acaccgatcg cacttagaga ggagaatgaa gaatgaaacg tatactaaaa
     3121 atgaccatgg ttcttttctc tcttcttata cttgcgagtt gttccttccc tggtcttgcc
     3181 agcaatacag atgaagacac catttcgatc acaggtggaa tcacttcaga agcacagatc
     3241 ttagcaagtc tagttgccgg aatggttgaa cattatacag ataaaaatac cgcaatcatc
     3301 aacaatctgg ctactacaac tatcaaccat caagcgatga tgaacggaga tgcttcaatt
     3361 tcagcggctc gctacacagg aacagattta acgactacat tgaaccttcc tcctgaaaaa
     3421 gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg agaaaagata cggtcaaacg
     3481 tggttcccgt cctatggttt tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca
     3541 caaaaatacc atctatctaa agtcagcgat ctgaaaaatg tagcggatga attagtagct
     3601 ggtgtagata cttcttggat caatcgtaaa ggagacggtt atgacggctt ccaagaaact
     3661 tatggcttct ccttcaattc gatattacct atgcagattg gacttgttta tgacgcagtc
     3721 gaagcaggaa aaatggatat tgttcttggc tactctacgg atggacggat cgccagttat
     3781 gatctagtca tgttggaaga tgatcgtcaa ttcttcccac catatgatgc tgctccagtt
     3841 gtagacaaca agatattagc tgatacgcct catttaaaag aagccttaaa taagttaggt
     3901 cataccatca gtacggaaaa aatgcaggaa ttgaactacg aagcagataa taatctagtg
     3961 gaaccatcag tagtagcaca acgtttctta caagaaaacc actattttga agggaagtga
     4021 agcaattgga taaaatgaat gtctttcaac aatttttcta ttatttccag gaaaatggct
     4081 cctatatctt tgcacaattt atccgtcact tcctgatttc tatctatggt gtcctctttg
     4141 cagcagttgt cgggattccg gttgggatca tgatttctag gagacgtaaa ttagcaaact
     4201 gggtgattcg tttggcgaat atcatccaga cgatcccttc tctagccatg atctccattt
     4261 taatcattgg attaggcctg ggagtcaatg tcgtgattgt tactgtattt ttgtattccc
     4321 tcttaccgat catcaagaat acgtataccg ggatgatcca agtagacaaa aacatccttg
     4381 atgtcggcaa aggcatgggg atgactgcta gacaacgact attcatggta gagttaccac
     4441 tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt agttgttgcc atcgggataa
     4501 ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga tatcattatc cgaggaacca
     4561 atgcaacaga gggcacatcg attattttag caggtgcatt gccaactgca ttaatggcga
     4621 tcatcacgga ctggctttta ggtattttgg aaagacggct agatccagcc agccgtacat
     4681 cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct
     4741 tttttagttc tgtcattttt aaggcaataa tccactctga ttcttccctc cttatgggca
     4801 aagagttgct tttcttagct atttatccat tccgtatact ccaacttcat actgccaacg
     4861 ggttcatatc tgcatccacc gactaagttt ttttcttatc cgctaaggca ttttgccaat
     4921 ccattttccc atcactcgtc atggaattca taccacatga tctctaaata ctcgtctgct
     4981 tgttctttga attgggcatc aattcttaca tcctttggcg tggctttcat ttaagccttt
     5041 tccatcagtc ctcgattgtt cgatgccttc agctgcatca tcaaaactgg tgactgccgt
     5101 atcggtaact tcgatcatct tttatacaat cgggaacttg ccatcctcat ccttggctaa
     5161 aaacatatct agccattcca gcttctcgcc atgggaggtt tgcggttcct aaaaccggta
     5221 cacgattctt atggactgca tccgtcgcaa ctagacttgg cgatacgatg atccttcacc
     5281 agaagagcac ccccgtaaac caattgatcg atatattgcc aataagaaaa gacattggcg
     5341 taaaagatat cgatccctcg tgatgcattg ccgttgatac tgctattcat ggccgaaagc
     5401 gccacgactt taacttcttc cgtttgagtg acattcatgt tcggcaatgt cgctttggat
     5461 acccgctctg ctaaaggaac gacactggta ttgtatttcg tatctgtatc ttttccaaaa
     5521 gaccatgcca acgaatcctc tgggaaccaa taagacgact ccggttgatt gtccattgct
     5581 tttttcaaca tacttttggc tgtttctcga taaacgacat ttccaattgt cttcgcctca
     5641 ctttggcgat aatcgatggt cgttgccact gccaacacta acaacgatgc tccaatttta
     5701 ctgattttcc ttgtcacact tcttcctcct tgttttacat aaacccgtca acattccatt
     5761 cctaaactca aacaatgacc cttcaaaggt ggagatatag gaacaaatta aagaaatcat
     5821 gcaataaatc caagaaggtt ggttttagaa caaaaaaaga gtctcctttt tggggagact
     5881 ctttgttaac tatctaaaaa ggttggctct tctcacttca ctcataatgt gtccaggcag
     5941 aataaatttc tacaacttta ttttcctcat caactttgta aaccactcga tgctgtctat
     6001 tcagcctgcg tgagtatctg ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg
     6061 gcatatatgg atcttccttc aatgtctgaa tcacttcttc aaattgtttc tttaaattcg
     6121 tttgcttgat ttttcttaaa tccactttcg cagagttttt gattgcgact gtatagttac
     6181 tcatcaaaga gcttcccaat caatatcatc gatattcgta aagctactgt cgtctttttc
     6241 gcggtctcgt actttatcta aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc
     6301 tctccagtct tccagcccaa tcaatacagc attgtttcca ctacgatcac taataatctc
     6361 gatttcagta tgattttcat ttacctcttt caataactga taaaaatttt tacgagcagt
     6421 gctaggattc atcgttgtat tagccattgt ctctcctcct ttttctgata taattatagc
     6481 gtacttgatt aagtacgtca aaaaaataca ataaagcact taaattcagc aaacttttcc
     6541 tcttttttac atagagaaaa agaccccttt ttagggagga tctttgtcca cgctcacttc
     6601 ttactccttt acgactagcg gtagccaaac gtaaagtaat tggtaacaac gtatcatctt
     6661 tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca acaccaatac acgaaggttc
     6721 ctcgttgcag tgtgacttga ttgatatctt gaataacctg aggatacgca cgaaagattt
     6781 gtaacggtta ttcaaaactg attttggccg tcaagtcttc tactgcctca aaaatgattg
     6841 cctctttcgt ctcctgtcat tcatgttcac tatcgatttg atacttgctt agaccgttgg
     6901 gtttgtgaat caccaattaa aaatggcact gagttatggt aacaaaaaat ggtcacttga
     6961 cgaggctgag attcctactt atgaagacac atggcactta agagtcgagg taaaggaaga
     7021 agctgaaaat ataggaggct gtacattatt tggcaaagga ttcggaaatt atgatcaaga
     7081 catcaaaatc aaaatgtttt acagctaaat aggaagaata ataacatttc atacgctgtt
     7141 cccatcttta atggcttata gagggcacct ttagctgaga ataagacaaa acagaccctc
     7201 tagcttcaat taagagctag agggtctgtt tttgatttta aaacttggtt tatttcttca
     7261 aatggtagct ataggtgctg acaacgatat tttcacgcca agacaatcgc aatcttaacc
     7321 gcaaacttgt ttggttatgg agaatattct gccagcgtct gtttggtaca aattgaggaa
     7381 tcaacacagt agttgtatag ttttgtttcg ctgcattttt acttacgata tctacataac
     7441 ggataattgg attttcaatc gagcgataag aagagtggac gattgaaaaa cggacatctg
     7501 ggaaatgctt tttaaattct gcttcgattt ctttttcttt ttcgacatct tcgtctagcg
     7561 aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc gtaattcaac gcaccgatat
     7621 ttacccgtgt cacattcccg actaatacaa gaacggtatt cccgtcataa tcatgtagtt
     7681 ttgcatcatt ttctaaacga agctgttctg ctactttttt ataatgatca tggatcttat
     7741 aaaaaatgaa cataacgatt ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat
     7801 agacaaacaa aatcgcaatg attgcatatg agatgaacgc acccgtaata ttggcaatcg
     7861 atttgcttaa ccatcttttt ccttcttttt tccatttgac gaccatccct gtttgagata
     7921 aagcaaatgg aatgaacacg ccgatagagt ataacggaat caagcgttct gttgagccat
     7981 ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt gataatccca ttggaatagc
     8041 ctagtcgatc cccacgatct tgatacatgt gaggcatgaa tttatctttt gccagattgt
     8101 atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg
     8161 tagcaaattg aaggacgtaa tacaaaatac catgtccaaa gacagcttta ccaatttgag
     8221 acaaaacagt gacttctttt tcaggaacga tcccatacca atagttgata aatgtgatcc
     8281 ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg
     8341 ctcttggctt cttaaagaat ggtacagcat tactaatcgc ctccacccca gttaaagagg
     8401 aagaaccaga agaaaatgct cgtaaaatca aagcgataga aacacccggc acagccgctc
     8461 ctggaagtgc agtagcttgc aatggcacag cacctgtcac gatattatat aaaccaacaa
     8521 cgatcagtaa cgagatcaca aggataaatg tgtacaccgg aaataatagg aacgatgcag
     8581 attccctcag cccacgaaga ttcagcatca tcagtagcaa aacgattgtc acagaaatag
     8641 cgacttgatg accgtagagt gctggcaccg ctgatgtgat cgcttcagca cctgctgaga
     8701 cagatactgc tactgtcaac atgtagtcga tcaataaaga gccaccggaa atcaagccag
     8761 cattctttcc aagattctca ctgctgacga catatgctcc cccgccatga ggataagcat
     8821 ggatgatttg acgatatgat agcgttaatg aaatcaataa aataataaca aaagcggcaa
     8881 tgggtagcga ataccagatg gctgcagcag acaaagcgac taaaacgaca acgatttgtt
     8941 ccgtaccata tgcaatagat gataacgcat cagacgacaa taatgccaaa gcagcaaatc
     9001 gggttaattt gtgctcatca ttttcagcag attttaaagg cttacctact aacaaccttt
     9061 ttaagtaatc caatttctaa actcctttac acacaatttt acttcaagtt ttatagtcga
     9121 aaatttatag taaacaagat gttatagtac gctcactgac cttaaaagtc aataaacttt
     9181 aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct ttttcaaacg ctttaataca
     9241 gcaaaaatct aacatttttt tatgggcttt ttctttgaat tctataataa aaggatagaa
     9301 cttgacttag aaaatcaagt tctatccttt ttgatatctt aacttttgga agagagatgt
     9361 aaggctgctt tctacccatc attcttacta ctcgaagcat agcgcagttg tcacaacctc
     9421 ttgataaacg gtgtttaaaa gcttgcatct gcggtaataa gcccaaccaa attaaaaaca
     9481 taagaagctg tttttatttg gtcgttctta ttacttgatg cagagcagct tttttacaac
     9541 ctcttggtac acggtgttca atcagctgac cctcggtatt agctcaaaaa aacggcaaaa
     9601 tatgaggaac tatttttcca tttttttctc taatactcag gtcaaaacac tgatttcaca
     9661 acctcttttt ttaatgaaaa atatggctct catgcgccgc ttctttgaat ttcgtcattt
     9721 tttcttcgat gaacggatag attgccgttc ctacgattcc aaagacaaca aacaaaccga
     9781 tcatgatcca gattgctttc gtagcatttg gccaataaat tcctcctgca gattcccgta
     9841 acaagtttac cgcatgagta aatggcaaga acggattgat catttggaag aatttccctg
     9901 agacttggat cggatagttc ccgcctccgc cagagatcga cagtactaag atgataatag
     9961 cgatcccttt accgacatta tcgaataatg cagccaagac atagacgatc atcatgaacg
    10021 ctaaggcgat caagacagca aatgacacgc tgtagaccgg attttggaca tctactccta
    10081 gtaagaaaat attccctaat gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg
    10141 tcagcatacg agcaacgaat tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta
    10201 aatagtattc tgtcgtagca acacttgaaa gaagaacagc gccgacccac agacatagtg
    10261 cagtataaaa cggggtgcta gctgaaccgt tatttgcgat tggataaagc gcattggttt
    10321 gtagctcaac aggttgtgta aagaagtcac tttcttttgt tgcgtctagt ttcaataatt
    10381 tgatgacttc gcctagatcg acttcttgtt cgccttttcg gatcgcgtct gctgcttttt
    10441 ggataccagc tttgatattt ggccagtcat tgttgatcaa gtccgcagca gcgttcacag
    10501 ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa tgtaccggtg atttcatttt
    10561 ttagtgctgg ccaatcattt tggataaaat cagcggccaa tcctaatttt tgctgaatga
    10621 tcggtaattc attgttgtat aggtctgccc cttcattgat gccattgacg atggtatcca
    10681 tatttccatt cagcattgta ttggcatcat ggatttcttg tccaattgca ggcatttctt
    10741 tttgatattt ttctaaaatt gccactgcat tcgttacagt tgctttcgtt gagctgagaa
    10801 gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat
    10861 cgatgacttg gtctagtaga gaagtgacag tggaactgat ttgacctgta ttgataccag
    10921 caatgatgcc attgatatta ttaacaacgg catcaatttg atctagcaat tcatcaatag
    10981 ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga taggcggttt tgcagattgc
    11041 ttagcaaggg ttttaattga tttagctgat caataattgg ctgtaatttc gtatttccag
    11101 cacttgtttg caatttagtc aggaactcga ccagtttatc gattgcattt tgttgttgag
    11161 atattccgtc aataaagccg ttcaatacat tgctgatgtt tttcttttca tcatcagtca
    11221 gcttaccatc ttcaatagct gttcttacag tatctattaa cgaacctgtc gttgttgcca
    11281 cttgtccaat tgacttcaat gtaacatcta cactgtttgt gatgcttggt atcgcatctt
    11341 tcagctgaga ggcacctgat tttgtttggt ttgctagatc acttgcctga ttttctaaat
    11401 ttttcacatc tggcaagata tcttgtactt gttggatgat cgtcaagcct tgttttgctt
    11461 catcgattcc ttggttcatt gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta
    11521 gttgcttacc ggcattttgg atctctggga ttttttcttg caaatcaagg atgatttttg
    11581 cttgatcttt caactcaggc attttgtcat tcaatgcaac gactttttca cccatctcat
    11641 ctactttagg gatgtaatcc acgaattcat ttgctttatt cagtttttcc ttgatttcag
    11701 gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt
    11761 catctgttga taaaatcata tctttaactt tattgatact tactaggttc gtatcgatgt
    11821 cgtaacctat ctcattgaat actttcaata aagtcgaact ggctgttttg ataaattcat
    11881 ttgtgatttg cgattggatc gaacttgctc ctttatcggt gattttcggt gcaatcgcat
    11941 tgattttttc atttaccgta tattcgattt ttggtttctt gatatcacca ctagtaaaac
    12001 tcagcagatc ttctgagaaa tcctttggca agtaaatacc tgcgtaatac tttccggaac
    12061 ggactccgtc ttctaattgt tcttttgaat caacgaattg ccatcctaat tgtttatttt
    12121 tatgaagcga ttcgatgact tgctccccaa tggccacttc tttaccttga aactctgctg
    12181 gcttgtctgc actgtaaaca gcaattggca gctctccagt atttccatat ggatcccata
    12241 atgctttgat gttaaaccac gcatatagcg aagggatgat catgatcgcg atgatcagaa
    12301 gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag caaatataat cgaagcgtat
    12361 ttttgattga ctgcatagtt ctcccccttc ttcttttttc agctgaatta ctttaccatg
    12421 tatttcatac ttttttcaat cggctttttt caaaaaagtc gaatttttgg acatatcacg
    12481 gcaattgtct cattgtaatc tcttacatat tgagaaataa ttaaggatta cagcctttac
    12541 tttatcatga aataaaaggg aaagataatt ttatgccaaa gtttttatct attatacgta
    12601 tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac aaaaatgttt cagctttttt
    12661 cgttttttat tcctgtattt cttatttttc gaatgacagg atgattttcc cagcaggagg
    12721 atgtccttca actagctgat gtgcttggat gacatgctta agtgaagcag acagattcat
    12781 tgaaataaaa acatgaaagg ctcctttttg gtaggctttg attatgccag caaaggcttc
    12841 tgcatctaga tattcctttc ttggaacaaa cgattcataa aagccttcct ttttttgccg
    12901 caaatctaga tctgggaggt catttaatgc aacatacctg ccgcctggtt tcatgatctg
    12961 gatgccggtt tctcctttga tacttccttt cgtcgcatcg attacaaggt ctgcctgatc
    13021 agcaaattgc agacctggat ttgttttatc ataagcagca aatgctgaag ctcctaattt
    13081 ttttaccttt tcctcatttt tactggatgc actggttaag attcggattc ccttttcatg
    13141 gagaagctgg atcagacttg acccgaccgc acctgatgct cctagtatca ttacagtatc
    13201 tgtcggctgg atttccgtca aatggttgat tagattataa gccgtaattc ctggcgtgac
    13261 cattccggct gcttcttccc aactcatttt atctggaatt tttgctactt ttgctgatgg
    13321 caacacgact tcttctccgt aagtcccgcc gactgcatgg acagctactc gatcacctac
    13381 atgaacagtt gtgacatctg aaccaatctc tgtcacaata ccagcgccat cattacctgg
    13441 tacataaggg aatttcaatg ttcgtatctc tttcatttct cctaaacgca aggcaacatc
    13501 ataaggattc acactgaatg cttttatttc tacacgaaca tgtccagaac cgacttctct
    13561 gggatgagca tcgatttctt caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa
    13621 tcttcgcatg gtcaccatct ccctttttct ttaagtttac gtttatgcct ttattttgac
    13681 aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca aaatagttgt cttttttcgc
    13741 gtaacgtgtt aaattattta tctaaaagcg taaagattac gatttacgct aataaaaaat
    13801 aattggagga atttgttgat ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa
    13861 gaaacgattg aacgctatgc tgctttacgc caggaattaa aagcgcaaaa agattacgaa
    13921 ggcttgcgta aacttccttt agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc
    13981 gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa
    14041 ttagcacata aaggtttgat tccaggagta aaaaaagcca gctggtaatc caagtctggc
    14101 tgtaatgtaa aggaggaggg cgcatggacc actccttgga tcatcaaaaa agatacgttc
    14161 gcttcttcta gcagaaatgc tggtactaga agcagacgta tcttttttta cgcacagctg
    14221 gtcctttttt atatgtaaag gctgcatggt tacttcgcta tatttattta gtaacaggag
    14281 tcagtgcttc gatacccaca ctaattttca atgctcggtc aacttctgcc ataatgggtc
    14341 gatccaaatg gcagaccttt tctttcaatc ttgatttatc gatcgttctg atctgctcca
    14401 acaggataac ggagtctctt tctattcctg ttccagtagc tttgatccca atgtgagtcg
    14461 gaagcttagg tttagccatt tttgccgtta tggccgcaac aatgatcgtc gggctaaaat
    14521 ggttacctag attattttga ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca
    14581 cgactggaga aagatcagca aaataaatat ctcctctttt taccatagga tcctccttat
    14641 tcttgatatt ctcttggtat ccgctgtcct aatccgcaag ccacttcata gtggatcgta
    14701 cctaattgat ctgctatatc ctgcatagtg atttctttgt ctgcattttt gccgataagc
    14761 gtcacttttg ttccgacagg aaattcttga ggcaatcgga tcatcagttg atccatacat
    14821 acacgcccaa tcgtttcaca gtagttccct tctaccaata gagaaaaacc ctgcatcttt
    14881 cgtggccagc catctgcata accgatcggt atcgttccga tccactctgc ttcaggagtg
    14941 atatatgttt ctccatagcc gattccttca cctgctggga gttttttgac ttgaatcaat
    15001 tcagaaacca gctcaagtgc tggctgcaat ggataaactt ccggtagtgc gtgcccagag
    15061 ggattaagtc cgtacattgc tactccataa cgaatcatat tgccgattgt ttcatcatgc
    15121 cataaagccg ttgcactatt gctgacatgt acatatcgag gaagttcggg aagttttttc
    15181 agcacttcta taaagcgttc tttttgcaga ttccaatatg tatcatctgc ctgatctgct
    15241 gtagaaaaat gggtaaataa accttcccat tctaatacac gactttcttt gatgaatgca
    15301 gctgcctctt ttacttcttc aggtgtacaa aatccgatac gacccatccc agtgtctgct
    15361 tttagatgaa tcgaaagagg cgtctctagc ttacttttct ctaaaacagc agctgctgct
    15421 tgcaaccatt cccgtgtacc tgcagttact gataaatcat gagcaacagc tacagtcagt
    15481 gcgtcgtaag gaaccatatt caagataagg atgggctgag taaatccagc ttctctcaac
    15541 tcgactcctt catctaaatt tgaaacacaa aagcccgaag ctccacctgc aactgctgcc
    15601 tcagctgttt caatagctcc atgaccgtat ccgttcgctt ttactactgc aaacaattct
    15661 tttccttgcg gaagtcttgc aacttcattt gctacatttt cagttatagc ttttttatgt
    15721 atcactgctt tcgttgggcg gtgccaagcg acaaccatcg tttttccttc tttctagtct
    15781 tccaaaataa tttgtgcaaa agctgtttca tttgtatgag taatactgac ccatacattg
    15841 ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt cattttttaa aatctcgaca
    15901 tcttgaaagg taacttttcc gatcccagtt ccccaagctt tagagaaagc ctctttgcaa
    15961 gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag gcaaggactg gaatagtttc
    16021 atttcatcag aggtcaagat tcgtgcaatg aattttggtt tttcttcgat cagccgagtg
    16081 atcctaggaa gttcgactgc atcgatccca attcctttta tcatatgctt ttctcttttc
    16141 aataaattta gaacactctc attctaccaa attataacca ttttgccaca aataagtcca
    16201 caaataacaa aaatgaaagt ttctcttaaa aaagagaaac tttcatttta tgtttaatcg
    16261 ttatttgaac ggattacaaa tccgcgtttt ttatcattgt gacgtttacc gccatctttt
    16321 tggctgttat tatttttgct ataaccgcct tttgatttgt ttccacgata attaccgccg
    16381 tcacgacgat tacggttgtt tccgccacca cgtttgccat ttttattgta tccttttttc
    16441 tgcattggca atgggcgttc tggtgtgatc ttcactggca ctgcatcagc tggatctttt
    16501 gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag aatattcttc taataattta
    16561 tctgctgttt gcaggtattt atctagacca ttttctgcaa gttttgtttc gatttgttca
    16621 actgcagcac ctaattgacc tttgaatgct tctttttcgg ttggtggacg taaagtcgtc
    16681 atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg
    16741 aaagtcacag acataccgcc ttttccggca cggcctgtac gtccgatacg gtgaacgtag
    16801 ctttctggat cttgagggat atcatagttg tacacatgag tgacacctga aatatctaat
    16861 ccacgtgcag caacgtctgt cgctacaagg atatctaaat gaccgctctt aaatgaacgc
    16921 aatacgctca ttcgtttttg ttgagacaaa tcgccatgga ttccttctgc acggtaaccg
    16981 cgtgcttcta atccgcgtgc caattcgtct acacggcgtt ttgtacgtcc gaagacgatt
    17041 gttaattcag gtgtttgaac atcaaacaag cgagtcatga tatcgaattt ttcgtattct
    17101 tttgcgcgga catagtattg atcgatcaag tcagctgtca tttctttcgc tttgatcttc
    17161 acatgatgtg gatttttcat gaatttaacg ccaatattct tgatagctgg cggcatcgtt
    17221 gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg aaatgatttt ttcgatatct
    17281 tccaagaagc ccatattcaa catttcatct gcttcatcca aaactaatgt ttgaacggtt
    17341 ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac gtcctggtgt acccacaacg
    17401 atatgtggac gatctttcaa gccacggatc tgacggccaa tatctgctcc gccgtaaacg
    17461 gcttgtacac gtactttttt gtcgcgccct aaacgatata attcttcttg tgtttggata
    17521 gctaattcac gtgttggtgc gataactaaa ccttgtaatt cgtgacgatc tggatcgatt
    17581 ttttctaaca ttggtaatcc aaatgcagct gttttccctg tacctgtctg tgcttgtcca
    17641 ataacgtctt ttccagctaa tgctagtgga atcgtttctg cttggatagg cgttgcttct
    17701 tcaaaaccag cgcgttcgac tgatttcaac aattctggtg ataattctag ttctttaaat
    17761 ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt agcttttttg ctaccccgtc
    17821 gatttgttcg gtcaaagtgt attgtttctt tttgacagtg gccacgcacg tttttatcca
    17881 ttcttagccc ctgtggcacc accgaaaaat cactttgcga agtttaggca ttagaaaagc
    17941 caaacgggtc gcgttcagct ttatcattat tatgacatct ggcttcaaca agttgtttct
    18001 atggcaaaac cagtccaatt tctcttcatc tttcggcaat aggttattct aacatagttt
    18061 ttcgttttct gcaagtttac agatttttat ttcatttgct gaagttgttc taccacttca
    18121 aataagccca tgctgttgct gccttttagc ataatactat ctgttgcttc aagattttgt
    18181 ttgatagcat caatcaattt attcttttct ttttccaaat agaacacagg tagttggggg
    18241 tatttttggt tcaattcttc ttttagtgca tgcatttgtt ccccataaag gaaaatcatg
    18301 gcgaatttct caggatcgat atgttcactc atttgcgcat gcatatttaa agactctttc
    18361 cctaattcca gcatatctgc taacacagcg attctgcgtc cttttgttgg cagattttta
    18421 aaagtatcta ataccagtcc catggctgtt ggatttgcat tgtagacatc gctcaaaata
    18481 gctgcaccat ttcctgccgt tagccattcg gttctgtttt gagtgataga aacatgggcg
    18541 agcccttggc gtatctcagg tatggacagt ccaaagaagc gcccgatcgt atacgcaatc
    18601 aaagcattcg ttacattata acttccaggc agcgggatcg taaatgtttc tccttctact
    18661 acaaaatcgg tttgtgcttt tccttttgct gtcacttccg catgaacatc gccatttcca
    18721 ataccgaatg ttgtgactgt ttgtactaat gttgccgtta aaggtgtcag caacggttca
    18781 tctgcgggca caacgagtaa tccgtctgat acaagtccgt cagtgatttc cattttggct
    18841 ttagcgattc cttctcgcga cccaagattt tctatgtgtg cttcaccgat cattgtgatt
    18901 gctgcagctt ttggttgagc cataagtgaa agttccgtga tttcattggc gtgatccatg
    18961 cccatttcca aaacgatctt ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga
    19021 ccaatattat tgttgtaatt tccttgcgtc ttatatgttt tgtatttttc agacaagaca
    19081 gacgcggtta gatctttcgt ggtggtttta ccattgcttc ctgtaattgc aacgacttct
    19141 gcgcctactt tttccaagta ataggttgcc aattgctgca tggctttcaa aggatctgct
    19201 acaggaataa ctggaaaatt ttttggagct tgttcaacag gcaagctcca aaatgaagca
    19261 gatgctccgt ttgtgatcgc ttgctggata aattcatgtc catctcgcgt accagcaaga
    19321 ggaacgaata aacttccttc ggttatcttc cggctgtcaa attcgacatt ggtaatcttt
    19381 gtcagtgcag agcattcgct gcccacggct tgtgcaattt cttgtattgt tagattcatt
    19441 gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg
    19501 actctcactt ccaagtaaat ttctctattc gtatttagaa gctagaatga acgcggttac
    19561 gcaatcactc cagcctcttc tttatttctc tttattcatt tttttcaaaa aaagattgac
    19621 gctgatggta tcgattcatt cctaactgga tcagttcttc aatcaaatca ccgtatttca
    19681 agcccatatt ttcccataag agtgggtaca tactgaactc cgtaaatcct ggcatagagt
    19741 ttaattcatt caggaataat tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc
    19801 cgcttccacc taacatcgtg taagctaact tcgcgtactc ttgcgctttt tgataaactt
    19861 cttctggcac ttcggctgga atctgcattt cgattttatt attgatatat tttgcttcat
    19921 aatcatagaa tgctacgtct tttacgactt caccaggcaa agtcgtccga acgtcttcat
    19981 ttcctaatac agcaacttcg atttcgcgcg cttcaattcc ttgttcaacg attgctcgag
    20041 aatcatactg ataggctgtt gctaaagcat tttgcagctc ttctcggttt tctgcttttg
    20101 taatgccgac actagaaccc atattcgccg gtttgacaaa catcggataa agcaaagaac
    20161 cttcacattg atcaaatact tttttaggat tttctttcca ttgattctta agtactggta
    20221 cataaggaac ttgcggcaca ccagcagctt gtaaaatata cttggtcatg attttatcca
    20281 tggcacatgc actggtcaat acgcctgcgc cgacataagg catattcaat gtctctaaga
    20341 agccttggat cgttccatct tccccgtttg gcccatgtaa aactggaaaa acgatggctc
    20401 cttcttcttt gatttcgccc ggattgatca cttttcctgt aaagccttcc tctgtctgtc
    20461 cacttgggtc ccatgaaaga tgcaagacat ctttgctggc aggtttttct gttagtaatg
    20521 gacctttgac ccattgtcct tcttttgtaa taaatacgag ttgaacttgg taataattat
    20581 aataaatggc atttaaaact gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc
    20641 gtccgccata tagtaaagta atcttcaaaa gattgtcctc ctgtattcta aatcgttcag
    20701 tgatttactc tcatatttta gcacaaaaca aaaataaacg aataacttat ttataaaaaa
    20761 acgagccagc ttctaaaaga acgagcgtca tttatttttt gtcagctaga ttatttgtcc
    20821 cgttttttat aaaaagttat gataaagaaa aggagggatg atgatggcgc aaacaaatcc
    20881 acgcagccgc ttggcagaaa tcattcgagt gttcatcaat tacaatgtag tgccaaactt
    20941 tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt gaagaactag gccccacctt
    21001 catcaagata ggacagatgc tttctgttcg agaagatttg ctttcttctg ccttcactca
    21061 aacattcaaa acattacaag atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac
    21121 gatcgaaaca gaactttctc tttcattatc agatatattc gatgattttt caaaatcgcc
    21181 ttttgcctct gcttctatgg ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt
    21241 agtcgttaag atccaacacc ctaacatcgc cgaagagatc cgacttgatc ttcaactatt
    21301 tgaacgagcg atccctttga tcaaatacat tcctgaaact agcgtagttg atctaaaagg
    21361 ggtactccaa gaagtaaaac gttccttgat caatgaaatg gacttcttaa aagaaagtca
    21421 aaatggcgaa caattctatc aaaagaacaa tggctggaaa gagatccgca gccccaagat
    21481 ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt
    21541 gaatcattta atgaacgccg aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa
    21601 gcagctgaaa caagaagttg caaagctttt agttgagaac tttatgaaac aggtgtttga
    21661 tgatggtttt ttccatgctg atcctcatcc agggaatctg ctattccatg tactaacaaa
    21721 agaagaacag acacaagcta gccgaaaaac tgaaacagtc catgaaaaag agttcggttc
    21781 ctttgctttt cgagcctcca cttctgcaga agaccctgtt gcgccatata ccatcaacta
    21841 catcgatttt ggtatgatgg ggcatctttc tgcaggactt aggcaaaaac tcacacaagc
    21901 cgttttagcg ctgtatacga aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg
    21961 tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa gaactgacaa gttttcttga
    22021 acagtattat gattctccta ttgatgaaat caacttgcaa gaagtattca cacatgtcgt
    22081 gacgatttgt catcaaaata atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc
    22141 atttgggaca ttagaagggg tgatccgcgt cctcgatcct gaagtttccc tcatggaagt
    22201 cgcttcgcct tttgctcaac attattttct cactcatctg gatgtagaag atacattgaa
    22261 acaaagcgga ttagacttat tggaagggat gaaggctgcg cctaagatcc ctcaacagct
    22321 ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa
    22381 gcaagacaaa ttattgagca ggatcgaaag tatgatcaat cggcttgttt tcggtatgat
    22441 tttagctgca ttgatcgtag ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc
    22501 agaggtcgtt tccttattag ggatatttac gtatgctatt gccgcattcg tcattatttt
    22561 tttggcaatc gatgcattga tccaaatgta taagaagagg aaaaagtaga aaaaggttgt
    22621 gacagaaaga atcagcttca agaaataaga aggggtttta cataaattgt ttctcaaatt
    22681 tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct gaaacaccga gaataaaaaa
    22741 tgtgaaaaag ctgttctgca cccagtaata agaacaatca aaaagggaac atggaacaca
    22801 tttatcctgt ttccctgttc cctttttgat gtattcgagc ataaataaaa taccttcgtt
    22861 acctactatc ttctgtactt ggtaaacctt agtcaattgc cttttttaac gcttgacgaa
    22921 aagacatatg atctttctcc gtaaagggtt ttggaccctt tgtccttatg ccagcttttc
    22981 ttaactttcc actatgataa cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt
    23041 cttttccaga gtgatggaac actcgcacac ccttcggcaa tacaagtgaa gctaaaccat
    23101 aatcttgcgt gatcaaaaag tcattcttct taaccatacc gacgatttta taatccgcac
    23161 tatcagctcc gcggtctacg tagacgattt ggacatgatt agcgtattct ttggtcgtat
    23221 aatggtccac actggtcacg ataaccacgt caagaccata ggattctcct aattttatga
    23281 catcttcttt tactggagaa ccatctccat caatgaatag cctcattctt tttcgccttc
    23341 ttccataaat gataaacagt tactaatccg ctcagtaaaa gaccaacatt gatccatttt
    23401 gccaagataa gcagttgtac actttctatc ggcactgatt catggttcag cgtgatcaat
    23461 aatagatgga ttggctctcc catttctttt gctaaaacaa acaaaagcgt catcaataaa
    23521 aactggtgga tcacactccc tttattttga gtagtatact tgacaacgat ccggcgatcc
    23581 attggaatag ctgtatcagt ttgataatat tccttattta gccagctgcc tgttactacg
    23641 tgccagaaac taagcagaaa gacacctatc gcaaaaccat ttggaatcaa gaggaccaat
    23701 aaagaagaac tcagtccaag caattgcata gccaatggag accatgttaa acgtttcaaa
    23761 atccatggtc cgactatttt tgctgcaatc aagcctgctg cataaggcaa atacataaaa
    23821 atcgaaagtt tttctaatcc gtacagtatg ccaacataaa aactgctaaa taaaaaaagg
    23881 aaattcccta gcattccatt tagaaaagta aacagattta gccagcttgg caacttccat
    23941 tccttcttct ggtgtcctaa aacaaacacg aacaagatga acagcagcaa gaaaccataa
    24001 atagcaagat caaaaagcct ttcatcgaat aacaatcggg catttctcaa aagaaacaat
    24061 aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag ctaccagatt tcttttgatg
    24121 tctttgaaat ccagttcgta acgcggataa tgactaaccg tatggtaggc catgacgtaa
    24181 aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct
    24241 tgatacagga gaaatagcca gatagctgca aataagtact ttttcccatc catattgata
    24301 aaaccttgcg tcttttcgtg aaaattgacc gtggtattag caggtacaag ccatgctgca
    24361 ctcagcccta gcaaaacact tgaaaaataa aataaaggaa aataaaatac gcctaatatt
    24421 ccaagcaatg aaccagcacc accaatcagc agagcgatca tcagcaacgt gtaactatct
    24481 agaccaaatc gtagactgtt gactaaaaat agtccagtca tccgaaaggc ataaaacagc
    24541 gtaaatggca aaatcgtcag ccaattatgc gagtctgtta gtcccaaaaa taaaagataa
    24601 ggaataaaaa taaccgtgtt acttaagata aagggcgttg tttgtgtaaa attacgccca
    24661 aatcgtttga gtttttcgaa catgacaatg gctccttaaa cagtcttata actaatctgc
    24721 tcttcgattt tagcattaaa ggggaaataa accaatttta cagaatatat tcttgtaaaa
    24781 aaaaatacag aaagaagcat aagcttcttt ctgcattttt acggtacttg attactcaag
    24841 cagacaagcc cttctccaca aaagtcttgc ccgacacccc tgcatccggc aggtgataaa
    24901 gatagaaatc aattatcctg tgcctccaaa atcaattagg agctctgtaa accagagtcc
    24961 ttctcgaccc gtcgcataaa tttactttaa cacagttcct atgtttatgc gagagctttt
    25021 ttcattttat aatcgaccat ttgaaatcct tgaccgatat ctgaaataag ttcttctgta
    25081 atctcaaatc cttcatgctt ataaacctcg attgcttgat gattcccctg attcactcgc
    25141 aaaaagatct ctctttcctt tgtttgcgca gcaagttctt cataccagcg aaaaactgaa
    25201 gaagtcaatc cttgaccacg tactttattt agcaaatata atttacttaa ataaattttt
    25261 ccatttatct cttcataagc agtgtaaccg acagtctttt cttcgctttt taataaaaag
    25321 taggacacac cttctgtcag ttctttttga atctgttttt ttgactgata agttttcagc
    25381 atgtaatcca cttgtttttg accaatgatc ggcacaaaag cttccggcca tacttcttgt
    25441 atgactgcca tcagctcatc cagttcattt tctgttactt ttattttttc catacaccca
    25501 cgtccttttt tacattataa atgaccttgc gcttgatgga ataaaaagag catgatcatg
    25561 ctatacacac ccaccgacca tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa
    25621 gataatttcg tcaaaccagc tactagacag atcaagtcgt ctggcgcaaa gggaagcagc
    25681 aaggtaacaa ctagtacttt tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat
    25741 ttctgatact tttttggcga taaaataagc tggacaaagg ctacgccata gtaacggaca
    25801 agcaaaaatc cgattgcttc cccaatcact aggccaatac aactatataa aagcccaaat
    25861 ccattgccaa acatcagcat gcccgctact gaggagatcc ctcccggcaa aataggaatg
    25921 atcacttgga tcacttgcaa cagaacaaat atcatcactg catacttgcc aaattgctgg
    25981 ataaacgctt gcaaagacgt gctcgatcga aaaatcccat gatgataagc ataaagaatc
    26041 aacacaaaga aaaaaaacag accaataatg ggcatgatct gaagacattt ttgtaaaact
    26101 gatccttttt tagacatcta tattccccac atcttttttc atttattaaa actgcctc
//
LOCUS       DACBYO010000032        25461 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.032, whole genome shotgun sequence.
ACCESSION   DACBYO010000032 DACBYO010000000
VERSION     DACBYO010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.032"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            132..3659
                     /locus_tag="IVD26_001322"
     CDS             132..3659
                     /locus_tag="IVD26_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP6079309.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3656..7378
                     /gene="addA"
                     /locus_tag="IVD26_001323"
     CDS             3656..7378
                     /gene="addA"
                     /locus_tag="IVD26_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAP6079310.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7447..7788
                     /locus_tag="IVD26_001324"
     CDS             7447..7788
                     /locus_tag="IVD26_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6079311.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8097..9140
                     /gene="pheS"
                     /locus_tag="IVD26_001325"
     CDS             8097..9140
                     /gene="pheS"
                     /locus_tag="IVD26_001325"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAP6079312.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9145..11565
                     /locus_tag="IVD26_001326"
     CDS             9145..11565
                     /locus_tag="IVD26_001326"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAP6079313.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11735..12745)
                     /gene="trpS"
                     /locus_tag="IVD26_001327"
     CDS             complement(11735..12745)
                     /gene="trpS"
                     /locus_tag="IVD26_001327"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAP6079314.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12999..13736
                     /locus_tag="IVD26_001328"
     CDS             12999..13736
                     /locus_tag="IVD26_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP6079315.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13750..14565
                     /locus_tag="IVD26_001329"
     CDS             13750..14565
                     /locus_tag="IVD26_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAP6079316.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14578..15225
                     /locus_tag="IVD26_001330"
     CDS             14578..15225
                     /locus_tag="IVD26_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP6079317.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15241..15897
                     /locus_tag="IVD26_001331"
     CDS             15241..15897
                     /locus_tag="IVD26_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP6079318.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16059..16880
                     /gene="racE"
                     /locus_tag="IVD26_001332"
     CDS             16059..16880
                     /gene="racE"
                     /locus_tag="IVD26_001332"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAP6079319.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16883..18238
                     /gene="rph"
                     /locus_tag="IVD26_001333"
     CDS             16883..18238
                     /gene="rph"
                     /locus_tag="IVD26_001333"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAP6079320.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18239..18757
                     /locus_tag="IVD26_001334"
     CDS             18239..18757
                     /locus_tag="IVD26_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAP6079321.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18864..19364
                     /locus_tag="IVD26_001335"
     CDS             18864..19364
                     /locus_tag="IVD26_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP6079322.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19644..20564)
                     /locus_tag="IVD26_001336"
     CDS             complement(19644..20564)
                     /locus_tag="IVD26_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAP6079323.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20729..21742
                     /locus_tag="IVD26_001337"
     CDS             20729..21742
                     /locus_tag="IVD26_001337"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAP6079324.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21852..22607)
                     /gene="fabI"
                     /locus_tag="IVD26_001338"
     CDS             complement(21852..22607)
                     /gene="fabI"
                     /locus_tag="IVD26_001338"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAP6079325.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22827..23267
                     /gene="fabZ"
                     /locus_tag="IVD26_001339"
     CDS             22827..23267
                     /gene="fabZ"
                     /locus_tag="IVD26_001339"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP6079326.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23382..24143)
                     /locus_tag="IVD26_001340"
     CDS             complement(23382..24143)
                     /locus_tag="IVD26_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP6079327.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24332..25426
                     /locus_tag="IVD26_001341"
     CDS             24332..25426
                     /locus_tag="IVD26_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP6079328.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8442 a         4420 c         5378 g         7221 t
ORIGIN      
        1 ttttgcgtat acttaaaaaa gtagaaatat cagaacctta aaaggatata atttgaagaa
       61 tatagaacaa atgttcagta ttttttgata taataaagga gcaccgtatc atgtgttgaa
      121 ggaggaaaag catgtcttta caatttattc ttggaaacgg gaaaaaagat caccgtcaag
      181 tcttgatcga cgaagcatcc gcttggctcg accaggatgc aagtaaccaa gtatttttcc
      241 ttgttcccaa ctacagcaaa ttcgaacagg aacaagaaat tttagcggag atgcgaagaa
      301 gaagcggaaa aaaaactttc agcacaacaa acgttcaagt atttagtttt tatcgtctgg
      361 cttggtattt gctgcaacag acaactcttc ttacaggaaa tgaattatca gaatcaggat
      421 ctgcaatgat cttgcgacag attttagaaa aaaatgagga agaattaaca atctttcgcg
      481 gagaaatcaa taaaagaggg tttattcgtc aattacaaga actctacagt gaattgcgta
      541 caggaaatat tcaaccagaa gacctgatgc ttttatttgg tgattcacct aatgcagaag
      601 accagcaact taaaatgaaa gacttgaagc tgattttttc agcttatgac agcgaattga
      661 ctcaacgtgc actaacaaat gaagatgcac tatctatact agcaaattat atgcagacac
      721 aagatttcaa caacgtcaaa tttattgtca gtggtttttc tcgaatcaat ggtcaagagt
      781 atcaattact gcaggcaatg atggaaaagg ggcaattggt tgtcgattta ttgctggatc
      841 gtccttatac agcggatctt ccagaagtac ttacgctctt tcatgagact ggaaagcttt
      901 atttccgtct ttttcaaagt gcaagagaac ggaaagtccc tatattagtg gaccgatttg
      961 caccagagca gactcgtccg acagagcttc aactgctgca aacaatgtgg gaagagacat
     1021 ctagccaaaa gaaagcggca gtacacaaaa tagggggaca agagcatctc catttgtggg
     1081 aagctgaaaa tccaactgaa gaagtccgac aattagctgt tgaaatcaga cgactagtca
     1141 gtgaagaaaa ctaccgttat cgtgatatcc aagtgctgac aaaaaatatg tctttatatg
     1201 gaaatatcct tcggccgatc tttcaagaaa tggcaattcc tttttatatc gatgaagaac
     1261 aaatgatgga aaatcatccg ctgatcgaat ggatcaacag tctgttcgct cttgaccgct
     1321 attcttatcg gctaagtgat attatgcgtt ttttcaaaac tgaattattt ctgtcgacgg
     1381 aagcagaaac cgaacttgat gaatggaaac aagagcgaga tgaattcagg aaaaaactgg
     1441 acatcactga aaatgtagca cttgcttaca attatcaagg aacttattgg actcgtgaaa
     1501 aagactggca gtttgtggcg tatgattttg aagcagaaca gattgaagac gtacagtatt
     1561 tggaagaaca gtcaaatacg attagacgat tatttcagaa agctgtacca gtatttttga
     1621 aaaaaataaa gaaaagcaaa acaggacaag aggccgcaaa tgttttttat caatttttga
     1681 tccaaagtgg cgtacagcaa caattattgt tttggcgtaa tcaggaagta gacagaggaa
     1741 acttagaagc ggcaagaaac catgagcaga catggggagc gctgattgat ctgttggatg
     1801 aatatgtagt aatttatggt gaatcggctt ttgactggtc actgttccaa gaaatcatta
     1861 caagtggtct agaaaatcta agttatggta aaatccctac cgcaatcgac caagtgcgaa
     1921 tcaatcgttt ggaattagtt cgaccaaatc aagctgccgt cacttttgca ttagggttga
     1981 atgatcaagt gtttccagac cgaaaagaga caaaaggatt gttgtccagt gaagaacgag
     2041 aagtattaaa tcaggccttg ccagatggac agtttttatt cgacccatca aaggaaagta
     2101 tctcttttga gcctttccaa gcctatcttg tttttctttc cggaacagat cgattatatc
     2161 ttagttatgc acaaagctat gacacagatg gttcgctgaa gatgtctcct tatttgcgta
     2221 gaatcacaga atatttatct gttcccgtcg agagaaaaga gcatttgacg atcgaaagcg
     2281 accctaattg ttatgtaggg acttacagaa gcggaatcaa tacagtcaat aggatttatc
     2341 gattagcttt agatgaaaaa aaacctgtac caaagcactg gcaaaagctc aaagaattag
     2401 tactgaattc gtcatggcga aattttgctt tacagatttt tgaaagtcag gaacatttaa
     2461 atgttcctgt ttcgatgcca gaaaaaatgg cggaagagct ttatggaaaa gagatttata
     2521 cttcaatttc acgtatggag aatttttata attgtgaata caaatacttc atgcaatttg
     2581 gtttgaaatt gaaagaacga actgtttatg gtctaactcc agcagcaact ggtgattttt
     2641 atcatgaatc attggatcgt ttcttcaagc tactgttttc aaaccaatta tccttagtga
     2701 atatgtccga tgcgcagcgt agagacttta ctgaaaaagt gctgcaggaa gtattcggag
     2761 aacttcggtt tgagatattg gatagttctg caagaatgaa ctatatccgc taccagttag
     2821 gacagacgat tcaaaaagtg acatgggctt tgcaaaaaca gagcaaaaat acaggcatgc
     2881 atcctcttca gacagagatt ctatttggtc agattgctgg agcaaaaggt atcacaggtc
     2941 tggaattacc gttgagtaat ggtggaaaac tccatgttcg agggaaaatc gatcgaatcg
     3001 atgtagcttc tgaacaagaa gatacttggc taagcgtcgt tgattacaaa tctagcggac
     3061 gttcattcga tgtcacagaa gcttattatg gcatggctat gcaattattg acgtatctgg
     3121 acgtagcatt gatggatgcg gtacgtttga ctggaaaggc ggctgttaaa ccagcaggat
     3181 catattattt acatgttcat aatcctgtat tgacggagac agatgatgta gagaagaata
     3241 cattgaaaaa atttagttat gatggcgttt ttgtcgatga tcccgctctt ttagaagtac
     3301 tagatcattc actggaagca aaagaacaat cactgatcta tccagtgaaa aaaaatgcga
     3361 aagatgaata ccaaaaaggt agtttcagta aagacaaatt tttcacggaa gaagaactgc
     3421 aactattcat ggcgcataat cgggaaaata tgcggttagc tggagatgcg attacttccg
     3481 gagaaatcaa actaaatcca gcttataaag ataaacagcg gattgcctgc gaattttgtc
     3541 cattcagaag catctgtacg tttgatgtga tgctgaaaga aaataattac caccgtctgg
     3601 agaaaataga taaggaagaa gcactgcgta gaatattgaa aaggagtgaa gaagagtgaa
     3661 tcaaattcct ttaaaaccgc aaaatgaacg attcacagat gatcagtggc aagcgatttt
     3721 tgatcaagga gataatctat tagtctctgc gtctgccgga tcaggtaaaa ctacagtgct
     3781 tgttcgaaga gtgattgaaa aactaaaaat gggttttgat atcgatgaat tattgattgt
     3841 gacatttact gaagctgccg caagagaaat gaaagaaaga attcaagagg cattacaaga
     3901 atccgtcaat agcgaaagtg accctgtacg tagacagcat tttactaagc agttagtttt
     3961 attgcccaca gcgaatatct caaccttaca tgctttttgc ctgacagtta ttcgacgtta
     4021 ttattactta attgatattg atccagtctt tcgcatgtta acagatgaaa cagaaacgat
     4081 cttgatgaag gaggatgtgt gggacgagct gagagaagca ctttatgcag aaaatgatga
     4141 acgatttttc caattaacaa tgaatttttc taatgatcgt tcagatgacg gcttgacgaa
     4201 tctggtgttt tctctttatg agtttgcccg tgccaaccct gacccccaaa aatggctaga
     4261 acagttaagc gataattatc gtttgcctga ggggctagcg aaatctcgat tatatcaaaa
     4321 acaaatccgt cctttagttt tggcagatat ataccaatgt gtacagttat atgaacagat
     4381 gactcagtta gcacaaggtg aaggattaga aaaaatgcat gagcaagtag ctggagaaca
     4441 acagcagatc aagaatatct atgaagcgtt ctcgcaagat cggttagaag aagcttatgc
     4501 tggtttggaa caactaactt tttcaacttt taagagcagt cggaaagcag aattgaaaga
     4561 aatttccaat gaagtcaagg gcatgaggga taaagcaaaa aaactgattc agcagataag
     4621 taaaagttat tttcctgttt ccccaagcca aatggaagaa ttaacggaca aagcactacc
     4681 gttagtcgaa gaaatgacaa aagtcacgca aagcttcatg gacggtttca gtatgcgtaa
     4741 acgggaaaaa ggtgtgctgg atttcaatga tctggaacat ttagcgttgc agattctcac
     4801 agaaaaaacg aaagatgtat ggctgccaag tgaagcttca aaacattatc gaaaaaaatt
     4861 caaagaagta atggtagatg aatatcaaga cgtgaaccaa ttacaagaag ccattttata
     4921 ctggctaaga gaacccgatg atacaaaagg aaatatgttc atggttgggg atgtcaaaca
     4981 atccatctat tctttccgtt tagcagatcc tagtttattt atcgggaaat acgagaattt
     5041 ctcaaagaaa gaaggcggac gtcgaatcgt tttggctgag aacttccgct ctagaaaaga
     5101 agtcctttct tttacgaatc ttatttttga acaactaatg gatccagcag tgggtcaaat
     5161 caattatgac gaagcagcca aactgatcca aggattttca gactttccag agaatgaaca
     5221 gtttgagccg gaaatcatga tctatgaaaa agaacaggaa gaatcagaga ttgagattcc
     5281 gacggatgat atactggaag acaaaacaga aggcgaactt tttatgacag gactaaaaat
     5341 tcgtcaatta attgattcct cctttatgat ttatgataaa aaatcaaaaa aaagtcgtcc
     5401 gatagagtac aaagacattg ttctcttgac acctacaaag aagaacaact taacgatttt
     5461 agagattttc aaaacattgg atattccatt agagatgaat gatgctcaaa actattttca
     5521 agcgacagaa attcgcacga tgatctcgct gctacaatta atcgataatc cctatcaaga
     5581 tattccgctt gcggctgtat tgcgctcacc gatcgtgggt ctgattgaac cagaattagc
     5641 cagcattcga ttagctaacc gtgcacatac ttactatgat gctgtgcttg cttatcaagc
     5701 atcaaacgaa gatgaattag cagctaagct ggaacatttt ggcaagcaac tagagcattg
     5761 gcgagaactt gctcgccgtt cttcgatcac tgacttgtta tgggatatct attatgagac
     5821 gggatatcta gagtatgtgg tcggtctgcc agcaggggca cagagacaag ccaatcttta
     5881 tgcattggtt gatcgtgcca aagcttacga gcaaagttct ttcagaggat tataccagtt
     5941 cgtgcgtttc attgaaaaaa tgcaagaaaa agataaagac ttagcagaac cagtcatttc
     6001 aatagaagat aatgctgttc gcgttatgac gatccatgca agtaaaggct tggaattccc
     6061 agttgtattt ttgttagata tgacaaagga gttcaactta caagacttgc gcaatcggta
     6121 tgcttttgaa gaaaaacttg gagcaggaat tcgctatatg gatcctgaaa cacgagtgtt
     6181 atatgatacg ttaccgtttc aagccatcaa attggcaaag caaaacaaat tgttgtcgga
     6241 agaaatgcgt aaattgtatg taggattgac tcgggcagaa caaaagcttt tcattgtcgg
     6301 ttcctataaa aataaagagc aaatgatcca aacgtggtct gaagcagctg atcatgagga
     6361 gttagttttt gatcctgcgc tacgtttgaa gggcagaagc agcttgatga attggattgg
     6421 ttacggattg atccgtcatc ctgaaatgca gaaatactta gaggaagaaa tttcgacttc
     6481 tcttcttcaa cattcaaatg cacagttttc tatttcatgg atgaatcagc aatcgatcat
     6541 tgaacaaaga cagttgcttg ctgaaaaaga actggttaac ttagatcagc agatgaaaga
     6601 agatgaaact ttattagcag attcgttaca aaaacgtctg gcatatgaat atccttatca
     6661 agcttcttca caaaccacaa gttatcaatc tgtatctgaa atcaaacgat tattcgaaga
     6721 tccagatgat acacaagaat cacgtttgac tctggaaagc agtcagaaca aagcagcatc
     6781 ccgtcaattt cgttatacgc aagaacaact agcagaacca aaatttttgc aaaaagatcg
     6841 gcaagtgtca gcagctgctg ttggaactgc tacgcatgct ttgttacaat tactgccatt
     6901 agagatgcca actacagaga gtatccatca aaaattacag gaattggtaa ggaaacggtt
     6961 agtagacgaa aaagtcgcga aaaaagtaga tgtttcttct attatatggt tctttcaaac
     7021 agaacttggt caacagctga ttgccaacaa agaaaacgta aaacgagaac aacctttttc
     7081 catgctgctt cctgctgacg aagtatttca agactatcca aatcaagaag atgaactatt
     7141 aatccacgga atcgtcgatg gatacctaga agaaaaagat catctcaata tctatgattt
     7201 taaaacagat tttattttac atccggatga tccagcagaa atagatgcaa tcgtccaaaa
     7261 atatcaagga cagctaagac tttaccaaca agcaatgtca gaagctttga ataagccagt
     7321 agaaaatgtt ttcctaattt tgcttcgagt gaaacaaatt ataaacatta acaaataatt
     7381 ataattgagc aaacttgact tatgttttgt aaggattatg ctatactctg ggaagaggtg
     7441 agtatgatgg agctaacaca gacagaattc gttttatgcc ctaaatttga aaaaacattc
     7501 tctattttag gaaaaaaatg gaacggattg attatcgatg tactactcga aaacggtccg
     7561 caacgctttg ttgagcttgc ggcaaaaatc ccgatggtca gtgatcgagt attagtcgaa
     7621 cgcttgaagg aattagaaaa agaaggaata gtcactcgaa actttgcctg tagcgaaaag
     7681 agccgttcag aatatctctt gactgaaaaa ggagcagact tgcaaaaagc gatgcgtcaa
     7741 atacaagttt ggagcgaaaa atggatcaca gaggaagaat gcggttgatt ttgtaaaaaa
     7801 aatcttgtaa actatagtcc atacgaataa gtaaagaacg atgacgaaaa agagtagttt
     7861 ggctaaacca gttcagggag atctgtcgca gactgaaagc agatcctgtg tttgaaaaat
     7921 gaagttcact ttccgagttc gtctgataaa atcagaccgg caattgtcgt taacgaagta
     7981 agagtgcggt gtaagtcatt tatccgcaaa ttaggatggt aacgcgaaga cctcgttcct
     8041 taacaggaat gaggtctttt tgttttgtat ttggaattta aaggaggaac aagcacatgt
     8101 ctctacaagc acaattagag agcttgaaag aagcaacgct cgtcaaaatc acagcggcac
     8161 aagatttaaa tgaattaaat caaatacgtg ttgaaacgtt aggaaaaaaa ggaccgatca
     8221 cagaagtatt acgtgggatg aaagatctaa gtccagaaga gcgaccaaaa gtcggaagtt
     8281 tcgcaaatga gatccgagat cttttgacag aagagatcga gcgaaaaaaa caagtattag
     8341 aagaagaagc gttaaatgca gctttggcaa aagaaacaat agacgtgaca ctacctggta
     8401 gaaaagtaaa acatggtaca cgtcatatcg tgacacaaat catggaagaa attgaagata
     8461 tttttgtggg tatgggctat cagatcgtag aaggatatga agtagaatct gatcattaca
     8521 atttcgaacg gatgaatctg ccaaaagatc atccagcaag ggacatgcaa gatactttct
     8581 atatttcaga cgagatattg attcggacac atacttcacc agtccaagca cggacaatgg
     8641 aaaaacatga tttctctaag ggtgctctac gaatgatctc gccagggaaa gtcttccgca
     8701 gagatacaga tgatgcgacc cacagtcatc agttccatca aattgaaggg ctagttgttg
     8761 ataaaaacat cacaatgggc gaccttaaag gaacattaga agtcgtaatg aaaaaaatgt
     8821 ttggggaaga tcgtgaaatt cgtttgcgtc caagttattt cccatttacg gaaccatcag
     8881 tagaagtaga tgtcagctgt ttcaaatgtg gtggtgccgg ttgtaacgta tgtaaataca
     8941 ctggatggat cgaaatttta ggagctggca tggtacaccc gaatgtgttg aagatgtcag
     9001 gaatcgatcc agaagaatat tcaggctttg ctttcggcct tggaccagac cgcgtagcta
     9061 tgttgcggta tggagtgaat gatatccgta atttctatca aaatgactta cgtttcttaa
     9121 gtcagttcaa gggggagtaa gaaaatgtta gtttcatata aatggctcaa tcgttatgta
     9181 gatttatcga atgtaacacc aaaagaatta gcggataaga tgtctgtgac aggaatcgaa
     9241 gtagagggag taacggttcc agaagaaggc ttgaaaaaaa tcgttgtcgg tgaagtcaag
     9301 gaatgcgtac cacatccaga ttctgatcac ctttctattt gtcaagtcga tattggcgaa
     9361 gacgaactgt ctcaaatcgt ttgtggagcg cctaatgtga aggttggaat caaagtgatt
     9421 gttgcacttc ctaactcacg tatcgctggt aatgtaaaaa tcaaaaaagg aaaaatgcgt
     9481 ggccaagtat caaatggcat gatttgctca ttacaagaaa ttggctattc agatagtgtt
     9541 ataccgaaag aatacgctga aggtatctat tatatgccac aagaagctgt aaatggcgat
     9601 ccagtttttc cttatttgga tatggatgat tcgattattg aattatctat cacaccgaat
     9661 cgtgcggatg cattgtcaat gcgtggcgta gcttatgaag ttggggcaat ttatcgtcag
     9721 actcctacat tcgatgacga aaagctggta gaatcctcac gtcctgctag cgataaaatt
     9781 caagtggaag ttgaagataa agaagcagtt cctgcttatc aaatcagaat cattgaagga
     9841 gtaagaatcc agccaagtcc tcaatggctg caaaatcttt tgatgaacga aggcattcgt
     9901 ccaatcaaca atgtagtaga tgtgacgaac tatattttgc ttttattcgg acaaccacta
     9961 catgcatttg actacgacaa attgaaatca aaagagatct ttgtccgccg tgcaaaagaa
    10021 aatgaaacat tagtaacact agatggagaa tctcgggaat tgacaactga caatctcgtc
    10081 attactaacg gcaaagaacc agttgcttta gctggtgtca tgggagggtt agactcagag
    10141 atcacgaatg aaacaacaac agttgcacta gaatctgctt tatttgatcc aatttcgatt
    10201 cgtcgtacag caaaacaatt taatttgcgt agtgaatcct ctgcacgttt tgaaaaagga
    10261 atcaaccatg cgactgttgg agaagccagt gaggttgctg cagcaatgat cgtttctctt
    10321 gcgggtgggg aagttctaca aggcgcggtc aaaggctcag agatcaaagc agaagacgta
    10381 tcagtgaaga tttcacttga acgcatcaat caatatttag gaacatctct tgtcgttaaa
    10441 gaagtaaatg agatttttga agcacttgga tttagctatg aagaaaagga gtatgtttat
    10501 tccgtagtag taccaccaag acgctgggat atccaaatcg aagcagatat tatcgaagaa
    10561 gttgctcgta tttatggata cgaccagttg ccatctacac ttccaagtgg agaaacggtt
    10621 gctggaagct tgtcaaaaga acaagaaact actcgtaaaa ttcgtacaat ctttgaagga
    10681 agcggattga gcgaagcaat cagttatgca ttgacaacag aagaaaaatc aagacagttt
    10741 gttataaatg aaagtaatat tacacgtttg gactggccaa tgagcgaaga acgttctgta
    10801 ttacgaatga atttgatcag cggactatta gatgatatca gttataacac tgcccgaaaa
    10861 aatacagaga ttgctttata tgaaattggt cgggtgttct tccaagaaaa tgatccacgt
    10921 acacatctgc cgcaagaagt aaaacatgca gcaatcgcta tttctggtat ttgggaagaa
    10981 aaagattggc agacgaaagc tcaaaatgta gactttttca ccatcaaggg tcttttagaa
    11041 aacttatttg aacaactagg catcactgaa gatgtccatt atcaaacagt gacagaaatg
    11101 aaggaaatgc atcctggaag aactgctgcg atttaccttg gcgaaaaatt tattggtttt
    11161 gtcggtcaag tgcatccaac gattacaaaa agttatgata ttccagaaac atatgttgct
    11221 gagtttgatt tatctgctat agtggaagct gctcaaaaag ggatcgtttt cgaagcagtg
    11281 acaaaattcc cagcagtcag ccgggacatc gctttgcttg taaaagaaac tgtgacaaat
    11341 caggaattaa cagaagttat ccgttctgct gccggaagat ttttaacaga tatccaatta
    11401 tttgatgtct atcaaggaga aaacattgaa aaaggacata aatccatggc gtatagcctg
    11461 acattcgtca acccagaagc aacattgaca gatgaagaaa tcaataaagc aatggaaaaa
    11521 gtcgaaaaag cgttggtaga aaacctagag gcaagtattc gctaagaagg aaaatatagt
    11581 aagtaacgat caagtagctt ttgaagacca tacatttgaa aaaaagatgt gacacaactt
    11641 cgtcacatct ctttttttga ttttaaaaaa ggaatagcac agagacgaga taaaaaaaca
    11701 ggcctttaca gcctgctttt ttagagtaaa tgaattaatg gaagtaattg attcccattg
    11761 ctgattttac ttcagaaagt gtttgtgcag ctactttagc agcttcttca ctacctttac
    11821 gtaagatttc cataacagct gaaggatctt tttccaattc ttctcggcgc gcacggatcg
    11881 gtgcaaattc agcttccaat acatcaatga ggtatcgttt gatctttaca tcaccaagtc
    11941 cgccgcggcg gtaatgagct ttcatttctt caattgcttc tttatctgtt ccgaatacat
    12001 ccaagtaggt gaagaccata ttcccttcta cttgtccagg atcttgtaca tggatgtggt
    12061 ttggatcagt atacatactc atgacttttt tctgtaagac atcggcagga tcggagatat
    12121 aaataccgtt tcctaacgat ttactcattt tgccatttcc atcgattcca ggtaatctac
    12181 ccattccttt tggtgggaat acgccttttg gttccaccaa gacttcacca tatgtatgat
    12241 tgaagctttg tacgatttcc tgtgtctgct ctagcattgg tttttgatcc tcaccaacag
    12301 gtacaagatt cgctttgaat gcagtgatat ctgctgcttg agaaacagga tagataaaga
    12361 atcctgtagg cacgctttca ccgaattttt tttgttcgat ttctgttttg acagtcggat
    12421 tgcgccgaac gcgtcctacg ctgactaagt tcaaataata catggttaat tcagctaatt
    12481 ccggaatttg tgattggata aataaagtag attttgcagg atctaatccc acggctaaat
    12541 agtctaaagc aacttgcaag acatttgatg aaaccttctc aggattttta gcattatctg
    12601 tcagtgcttg catgtcagca atcatgacaa acagttggtt gtcttcatct gcctgcatag
    12661 ccactcgggt ttttagagaa ccgacgtaat gccctaaatg cagcttccca gttggtcgat
    12721 ctcccgttaa aataatattt ttcaaaaaag acacctcttt acgatttgta agtctgagca
    12781 cttaatatct taccgttttt cctgaaaaga aacaacagtt cctaaggaaa aaacaaggaa
    12841 agaggataaa ataactaata gattagaaat ggaagaaata tttatgggag aataaacgtt
    12901 ctaagaaact ttacaaatta ctaaactatc agatataatg tattttatta tacatcttta
    12961 aaagaaatct tactaaataa taatgggagt gtaattctat ggcaatgatt aaatttgatc
    13021 acgtggataa atattatggc aagttccacg cattaaaaaa tatcaatctc gaattcgaga
    13081 aaggagaagt tgtcgttgtc attggtcctt ctggttcagg aaagagcacg atgcttcgct
    13141 gtatcaatgg attagagacg atctcttcag gtaagctgct gattaatgat actgacttgc
    13201 atgataaaaa gacaaaactg acagaagtcc gaaaaaacat cggcatggtt ttccaacatt
    13261 tcaatttgta cccaaataaa actgttctgg aaaacatcaa attagcacca atcaaagtgt
    13321 tgaagcaaga ccaggcaact gcagtcaaaa acgcggagaa atttttgaaa actgtcaata
    13381 tgttagataa gaaagattct tatccttcca tgttatccgg gggacaacag caacgggtgg
    13441 caatcgccag aggtttagcg atgaatcctg agatgctgct gtttgatgaa cctacttctg
    13501 ctttggatcc ggaaatgatt ggtgatgtat tagacgttat gaaaaaattg gctcatgacg
    13561 gtatgtcaat gattgtcgtg acacatgaaa tgggctttgc caaagaagtg gcggatcgtg
    13621 ttatcttcat ggctgatgga gaagtattgg aagacagcag aaatgtgaga gactttttcg
    13681 aaaatccaaa tgaagtccga gcacagcaat ttatcagtaa agttatcaat cattgatagg
    13741 aggaaaaaga tgcgcaggtt aaaaaaaata cgcctgattt tccttttagg cattgctttt
    13801 cttgcactag ccggatgtaa aggaaatggg ttggcaaatg aagatatttt agagcgaagc
    13861 aaatctacca atgaaatcat ctggggtgtc aagtatgata ctcgattatt tggaatgatg
    13921 gatattgaga gcagaactgt acaaggattt gatgtagata ttgcaaaagc aatcactaaa
    13981 aagatccttg gtgacaatgg aaaaacagaa tttgttgaag tcacttctaa aactcggatt
    14041 ccattattga aaaacggaaa tatcgatgca attattgcaa cgatgacgat cacagatgaa
    14101 cgaaaaaaac aggttgactt ttcagatgtc tatttcgatg ctggccaagc tttgttggta
    14161 aagaaaggaa gccaaatcaa aagtgtagat gatttgaatg cttctacaac ggttctagca
    14221 gtcaaaggtt ctacatcggc tgcgaatatc cgacagcatg caccagatgc aaaaatttta
    14281 gaattagaaa actatgcaga agcatttact gctttacaat ctggtcaggg agacgcgatg
    14341 actacggata atgcgatttt gttagggatt gcagatgaaa atccagagta tgagttagtt
    14401 ggtggaacgt ttactaatga gccttacggg attgcgatca acaaagggca agaaaacttc
    14461 ttgaaagctg ttaaccaagc gctagaggaa atgcatgcag atggcacata cgataaaatc
    14521 tatcaaaaat ggtttccaaa tgaaactgaa ggaaaagtag agtaaggggg agaggcaatg
    14581 agcgaattga tacaaactta tggaccaatc tttgtcgacg ggttcaagat cacattgttt
    14641 tcgagtgtct tagcacttgt gtttagtttg attatcggaa cgttaatggc aatcttccaa
    14701 ttatcaaaga ataaagtagt gagcgcctta gcaaaggcat atgtagaatt ttttagaaac
    14761 attccattat taatcatcgt gatgtttttt tatgttgtcg taccgattta ttggtttaat
    14821 ctagatggat tccaagcagg tacgattgga ttaacgatct atacatctgc ttttattgct
    14881 gaaacagtac gttcagggat tcaaaccgta ccaaaaggtc aaacagaagc aggactatct
    14941 tctggtttta cctattcaga aatcatgcgt tatattgttt taccgcaagc attcaaaatc
    15001 gttatcccgc cattaggcaa ccaatttatc aacctcgtaa aaaactcatc tattttagca
    15061 atcgtagctg gtttagattt gatgtatcaa ggagacttga tcgctagtga aacattcaat
    15121 accttcgata cgtatatcat cgttgggtta ttttacttag ttatcacgct accgttatct
    15181 tacttaatgg tttatcttga gaaaaaatgg gcggttcgtt catagaagga ggggaaatac
    15241 atggatttta gcggcgcttt ttcatggatg aatatccgtt ttttattgga aggattaaag
    15301 gttactgttg aagtttcatt gttttcgatc atttttagtt tcttgatcgg tggtctgaca
    15361 ggtgtgattc gttttgcgaa tatccctttc ttttccaaaa tccttggtgt agtgattgat
    15421 attatacgga atcttccatt attattgatc attttcttca cttactttgc cttacctcaa
    15481 atcggcattc agatgaacat cttctggtcc gctgtcgcag cattaacgat ttttgagtca
    15541 gctatgttgt cggaaatttt ccgagctgga ctcaatgctg ttccaaaagg acagatggaa
    15601 gcaggattat caacgggact gacttatgta gaatcgatgc gaacgatcgt gttaccgcaa
    15661 gcatttaaat caatgatccc ggcaattgtg agccaattga tttcactgat caaagatact
    15721 tcattagcag taatcatttc tttacctgaa ctttctcatc aggcacgtat tatttatgga
    15781 cagaacacca attatgtgct tccgatgttc atcatcatga cacttatgta cttcgtggta
    15841 tgttacgcgc tttctctgct ttccggttac ttggaaaaga gacggtacag ttattaatag
    15901 atgattcttt tagcggttgt ggcaaactaa agtcacaacc gcttttcctc tttccattcg
    15961 aaaaaaagag atttcgattg ttttaagcaa gtaagagcac ttgaaaattc acgctaaaaa
    16021 gtacacaata gggaggatag aatttattga aaaaaaggat gatacgattg acagataatc
    16081 gccctatcgg atttattgat tcaggtgtcg gcggcttgac tgtagtaaaa gaagccctga
    16141 aacaattacc gaatgaaaat attttatttg taggagacac agcacgctgc ccatatggcc
    16201 ctagacccgc ggaacaggta atccagtata cttgggaaat gacggattat ctggtggagc
    16261 aaggaatcaa gatgctggtg atcgcctgca ataccgcaac tgcggtggct ttagaagaaa
    16321 tcaaagctgc tctttctatt ccagtcatcg gtgtgatcct tcccggtact agagcggcag
    16381 taaaaaaaac acaaaataaa caagttggca ttatcggtac gattggtacg gtaaaaagtc
    16441 aagcttatga aaaagcactg aaagagaaag taccagaatt gactgtgaca agtcttgctt
    16501 gtcccaaatt tgtttcagtt gtcgaaagta atgaatacca ttcatcggtg gcgaaaaaaa
    16561 ttgtggcaga aacattagct cctttaacca ctaaaaaaat cgatacattg attttgggat
    16621 gcacccatta tccattatta cgccccatca ttcaaaatgt aatgggagaa aatgttcaac
    16681 tgatcgattc tggagcagaa acagtaggtg aagtatctat gctgttagat tatttcaatt
    16741 tgagcaattc accgcaaaat ggtcggacat tatgccagtt ttatacaact ggctctgcca
    16801 aacttttcga ggaaatagct gaagactggc ttggaatcgg acacttaaat gtagaacata
    16861 tcgaattggg aggaaaataa ggatgcgtca tgacgggaga aaagcccaag agcttcgcaa
    16921 actggagctt caaacaaatg ttttcaaata tccagaagga tcggtagtga tccgttttgg
    16981 tgatacaaca gttatttgtt ctgcaacaat agaaaattct gttccccctt ttttgagaga
    17041 aacaggaaca ggatgggtga cagcagaata tagtatgctg cctcgagcaa cgagtacgag
    17101 aaatcgtaga gaaagcagca aagggaaact ttctggtaga acaatggaaa tccagcgtct
    17161 tattggtcgt tccttgcgtg cagtagtaga cttggaaaaa ttaggagaac gtagtatcat
    17221 cgtagactgc gatgtgatcc aagcggatgg cggtactaga acagcaagta tcactggggc
    17281 atttgtggca ttgaaattag ccattgaaaa acttttaaga gaaaaagaat tgtcagaaga
    17341 tccaataaaa gaacatcttg ctgcagttag cgtaggaatc ttaccagatg ggacttgcgt
    17401 cacagatttg gattaccaag aagattccgc agcacttgta gacatgaatc ttgtaatgac
    17461 agaatctgga aaattcgtgg agattcaagg aactggagaa gaagcaacgt ttgatggtga
    17521 acagttgaat gaaatgctct tttttggaaa aaacgcgatt gaagatttga tcaaagagca
    17581 aaaacatgct ttgctaacag agtttgctca aaatgatgag cggatagaag aaacaaaaac
    17641 aatcatcatt gcgacaagaa atccaggaaa agcagaagag tttcgaaata tgttcaaaga
    17701 agcgggatat catgtaaaaa cattacttga ctatcctgaa ttgccagatg tggaagaaac
    17761 tggcagcaca tttgaagaaa atgcccgatt aaaagcagaa acgattgcac aattgcttga
    17821 tcagccagtc ttagcagatg attcaggttt gaaagtggat gctttaggcg gtatgccagg
    17881 aatctattct gcacgttttg caggggaaca aaaaagtgat gcggggaata acgccaaatt
    17941 attatatgaa ttgacagatg tgccggatga aaaaagaaca gcacaattcc attgtacgtt
    18001 agtattcgcg gcacccaaaa aagacagcct tgtagtagaa gcggaatggc ccggtcgagt
    18061 agcccgtata ccatctggcg aaaatggctt tgggtatgat cctttattta tcccagaagg
    18121 taagaaacaa acagcagcag aattatcgag cgaagaaaaa aacaagatca gtcatcgggc
    18181 tcaagcaatg aaaaaattga gtgccgagtg gaaacaatgg ctggaaggag agagatagat
    18241 gcggtattta gtagtaagtg ataatcatgg agacagagat atcctcgttg acttagtaga
    18301 tcgttatcgt tctgaagtgg atatcttttt ccattgtggt gattcggaat tagaagcttc
    18361 tgacccatta tgggatacat tccaagtggt tcaaggtaat tgtgattatg gaccaggatt
    18421 cgaacagaaa aaagtgatcc aaactggtca ggatacagta ttcatgactc acggtcattt
    18481 atcgaatgtc cgatttggtt tgacacagtt agcaatcgaa gctcgagctg caactgccga
    18541 tatggtgttt tttggtcata cccatcaaat aggctgtgag atggatcaga aaatcctgtt
    18601 tttgaatcct ggtagcattt ctcagcctag aggcccgatc caaatcccat catatgctct
    18661 tatcgaaagt ttagatgacc aaatttctgt tcaatactat aaccgtgccc atcaggcagt
    18721 tgaagagttg gccttttctt tttcgagaga gcgctgaata aaaaaactct aatttttaat
    18781 aaaaataagc tttattttat gaattttgca tccggtttcg gtaaaatagt agtgttgaat
    18841 gaaatagaaa tggaggccat cagatgattg gacctatagt aagagaaatg ctgctggaaa
    18901 atcaggaaac gtttttgatt cctgcagaaa atgtggcaaa tgttatgtat catcatccat
    18961 tgtcccatgg tttacttgtg ttatcgaagg tcggttattc caaaattcct gtattaggaa
    19021 aagatgatca ctttgtagga ctagtaagtt tatcagatgt ggtcaataaa atgattgact
    19081 tgcaaacaat cagcatggac ccgttagaag gactaacggt tgctgatgtg acagaaacag
    19141 atgttccgac aattgatgaa aattgggaac tagaagaagt actccatttg ttagtcgatt
    19201 cgcctttttt accggttgtc acagaagatc ggattttcaa aggaatcatt acaagaaaag
    19261 agctgcttaa agccgtaaac ttcatggtgc atgaattaga acgtcgtaat atattgtctc
    19321 cgaaaatcga agaattaaaa gaacaaatcg atatcgtgag ctaaagaacg agaaactaaa
    19381 agataatcaa aaaataagta gaaaaaacag cgtaccagtt ttgactttat cttgaaaaag
    19441 aggctgggac aaaagcgttt aactccaaga aataagaagg aattcacgaa aattgctttt
    19501 caaatttttg tgaatttcag cttatttccg aaggagttgc ttctgcttcc gccgtttata
    19561 cgtgtttaga gcgtgggaca aaagtgttct ttacttttgt cccacgctct ttttagtgag
    19621 attcgttgca tcgtttgtcc aaattatttt ccgacagcaa ttggactgtt cggaatcgtg
    19681 aaaccagaag ctgtcaattc tttgacatag gagctcaaga actcttcttt taaggcatat
    19741 tgttttccgt tcaatgcgta gcagaccgta cgaatcgcaa aattgctgtt tccaagatcc
    19801 actaatccaa agatagaagg ttcagtttgg agctcttctt ggtatttttc agctaatgta
    19861 cgatttactc gatcaatgat ctcatagatt ttgtcatatc cttcttcagg aacaatccga
    19921 atatctaaaa gtacttgcat atttgcacga gagagattgc tgatcgtggt gatgtttcga
    19981 ttcgggatga aatggacagt accatccgtt gctttcagct gaagggtacg gataccaaca
    20041 gatacgacgg ttccttcaat cgttaagttt gctagcttga tgtagtcccc aacatccatc
    20101 tgttgttcca tgataataaa aaatccggta ataacatcac tcatgaaccc ttgggcacca
    20161 agaccgattg ccacacctgc aattccggca ccagccaaaa gtgatccgat cggcacaccg
    20221 atagcagata aaattgcata gataaaaaag aaaccaaggg tataatgaaa aatagtattt
    20281 aaaagactat gtaaagtctt taagcggctc tcgtttagaa tggctttttt agaatactga
    20341 ttaaaagact tatcaatcag atattttccc acacggtgaa gaatccaaaa aaggacgatc
    20401 aaaaaaatca gatataaact tttttggata aaggcagcca aaatggcgtc ccaatcaatc
    20461 ccgtcccaaa accgctgaaa cgcatttact ttgctgacag cttgatctgt caatgtctcg
    20521 ccagaagagt ctgtcgtacc ggcagttgct aataatgaaa acataaaatc ctcttttcta
    20581 aaatttgatt ctttctgtat tgtaccaaga agttttcaaa aaaggaaata gcaaaaataa
    20641 ctataatgaa ggaaaaaagc tgaaaataaa atgacaaata atatggataa tgataaaatg
    20701 tggagaaaat aacgaaggtg gtaagtatat gcaaatcgat tggaacaatc taggtttttc
    20761 ttatatcaaa actccttggc gttttattgc caaatggaaa gacggacaat gggaagaagg
    20821 agaattgaca gaagataatt acctgacgat tcatgaaggc tctccagcgc ttcattatgg
    20881 tcagcaatgt tttgaaggtc taaaagctta tcgtcgaaaa gacggcaagg tcaatctctt
    20941 tcgacctgaa caaaatagtc gacggatgaa tcaaagtgct agacgattgc tgatgccaat
    21001 ggtccctgaa aagatgttcg ttgatgctgt caagcaagtg gtaaaagcaa atgaagattt
    21061 tgtgccgccc tatggaacag gcgctacatt atacttgcgc cctttactga ttggggtcgg
    21121 tgaaaacatt ggtgtccatc cagctccaga atatttattt gtcgtcttct gtacgccagt
    21181 aggagcgtat ttcaaaggtg gactaaaacc aacgaatttt attgtatctg attacgatcg
    21241 tgctgctcct aaggggactg gtgcagcaaa agtcggcgga aattacgcag cgagtttact
    21301 tccaggaaca gaagcaaaag aactggatta ctcagattgt gtttatcttg atccagccac
    21361 acatacgaaa atcgaagaag taggtgcagc aaatttcttt ggaattacaa aagacggaaa
    21421 attcatcact ccgcaatcgc cctctatctt accaagtatc acgaaatatt ccttgttgca
    21481 gttagctgaa gaacgactag gactgcaagc aattgaagga gatattttca ttgatgatct
    21541 agatcaattt gcagaagctg gtgcatgtgg tacagcggct gttatttctc caatcggtgg
    21601 gatttatcac aataacaatc ttcatgtatt ttatagtgaa acggaagtag gaccagtaac
    21661 aaaacggttg tatgatgaat tgacaggtat tcaatttgga gacatagaag caccagaagg
    21721 ctggattgaa gtcgtggaat aatttcaaag taatgagttg aaaaaaacgt aaaaagaaaa
    21781 aatcaggaag agactttaaa aagttttttc ctgattttta tatgttttac tttaaagaat
    21841 gcaacaaaag tttatgaaag atggacacct ttgtcaacgt agataatatc accgatgatt
    21901 ccgctggaaa gtgggctgat taagaaagca caagcattac cgacttcttc gatcgtcaca
    21961 ccttgctgat caggcgtacg agattcagat aactggatca gtttttgata gtctttaaca
    22021 cctgtgacag ctaatgtttt gattgcccca gctgagattc cattgacccg aattccttta
    22081 ggcgagaact cagctgccaa ataacggata gcagcttcaa gagaagcttt cgcaataccc
    22141 atcatgttat aattcgggat tgcgcgttct gaacctagat aagtcatgct aacgatcccg
    22201 ctgtttggtg caagaaacgg ttgtgcgtat tttgatacag caattaaaga gtagctgctg
    22261 atatcttgag ctaattgata gccgtctctg gaaatatcag acacatttcc ggacaattct
    22321 tctttgttgg cgtaagcaac tgcatggaca aggccgtgga tctccccagc atattcaccg
    22381 atggcattca ttgctttttc gatgctttcg tcgctagaaa catcacattc tacagtgaat
    22441 gcttcttcgc cgaccaattt gactaatgat tttttcattc gttcattttg gtaagtatag
    22501 ataatttctg ccccttgttt caacattgct tcagcacaac cccaagcaat gctttttttg
    22561 ttagcgacgc ccataatgac gatttttttt ccttctagaa atgacataat gactctcctt
    22621 tgtttctgat aaaaatttga tagtcgtaaa aaaatagaga ataatagcta aaataacttc
    22681 ttgatttctt aattattagt caaaatgttt tgattgtcaa actatttttt cttaaattaa
    22741 aaaaagattg ctaaatattt aggaatatga tactttgata gtcaaagtaa tgaaaatggc
    22801 aattgcctga aagaaggagt ttaattatgt cttacgtatt atctgctact gaagtaatgg
    22861 aattgattcc taatcgttat cctatttgtt atattgatta tgtagatact ttagaaccag
    22921 gaaaaaagat cgttgcgaca aaaaatgtaa caatcaatga agattttttc caaggtcact
    22981 ttcctgacaa tccagtgatg ccgggtgcgt tgattctaga aacactggca caagcaggtt
    23041 cgatacttat cctaaaatca gaagagtttc taggaaaaag agcttatatc ggtgggatca
    23101 ataaggccaa attccgtcaa aaagttgttc caggagatgt gctgaaatgt cattttgaaa
    23161 tcaccaaaat gaagggatca gtcggtacag cgttatctgc agcatatgta gatgataaaa
    23221 aagtctgtga gtgcgagttc acgttcatcg tcaaccaaaa tgcttgacta taaaacctga
    23281 tatagcaaaa caaaaggaag cttacttgct ttttatgtaa aaagaagacg cctgaatcct
    23341 agcatacgtt gtcatctatg caggattcag acgttatttt tttatttttg ttttgcttct
    23401 tgcagtatat tgattttatc gatttttact tcttcttttg gtttgtctga actatctgtt
    23461 tcgatatttg caatagcatc cacgacatcc attccttcaa tcacttggcc gaagacagta
    23521 taatggccat ctagtgaagg ataaccgccg tttttataag cgtcgatgat tgcttgagga
    23581 tagtcgtctt ttaaaagacc atcatgcata tcatctgtat tttgaacgat aaagaactgg
    23641 ctgccgttac tgttaggatc ttgtgagcga gccatagata acgcacctct tatattataa
    23701 aggtggttgt tgatctctgt ttcaaatcct tctccccaaa tgctttcccc tccagtgcca
    23761 tcgcctttag gatcgccacc ttggatcatg aaatctttga tgacgcgatg gaaagtcagt
    23821 ccgttgtagt aaccgtcttt tgcatgtgtc ataaagtttt caaccgcttt tggtgcgtgt
    23881 tcgggaaata atttgatttt gattgtgcct ttattcgtca ccatttcgac cagatcttca
    23941 ttttcggcga catctttcgt caattgtggt aattccaatg cgttcaaatc gacgctactg
    24001 gcagtcgtgc tttccgcagt agatgtactt tttgaacttt ctgtagacga actagaagaa
    24061 gtcgtgttgt ttgcagaaca accagcagca aacagcaatg ctgctgctaa actaatactt
    24121 aaaataactt tatttttctt cataactgtt cctttccaat ttactatttt gttatcttta
    24181 atgataacaa aatagaggga aaatacctac ttaaattatt ggaatttatc atttatttta
    24241 aaagaaaaag aaaaggtgta gaccatttac tttgtgtttg ctataatgta agtggataca
    24301 aaaacgaaaa gatgcaggag gaaatggtaa tatgggaaaa ttaggaatct cgatttatcc
    24361 agaacggtca acatttgaaa aggacaaagc gtacttggat ttagctcata agtatgggta
    24421 taaacgggtt tttaccagtt tgctgcagat caatgatgat aaagaaaaag ttctttcaga
    24481 atttaaagaa gtagttgatt acgcgaatag cctaggcatg gaagtaatgg ttgatatcaa
    24541 tccagcgtta tttgaacagt tggagatttc ttacgatgac ttatcttttt tccataagat
    24601 gggtgcctac ggggtccgct tagatatcgg attcacagga gcagaagaag caaaaatgac
    24661 gcgcaatcct tttggtatca aaatcgagat caatatgagt tcgggcacga attacgttga
    24721 caacatcatg agttattcgc caaacacgga taatttatta ggttctcata atttttatcc
    24781 tcatcgatac tctggtttag gatacgaaca ctttgttttt tgttcagaaa aattcagaaa
    24841 atataatttg aatacgatgg cattcgtcaa ttcgcaatct gctgagtttg gcccttggcc
    24901 tacgcaagat ggcttgtgca cgctggaaga ccaccgagat cttgaaattg cgacacaagt
    24961 gaagcattta atccttacag gattgattga tgatatttct attggaaatg cgtacgcaag
    25021 tgaagaagaa ttgaaagaaa tggcagaagc atttaacgcg gattatccaa cattgaaagt
    25081 agatacggaa gaaggtatta cagaaaacga acgaatctgc ttgtttgata accttcatag
    25141 ttatcgaggg gatcgctcag aatatatcct tcgttcaacg atgactcgtg tatactacaa
    25201 agataaagat ttcccgcctc ataatacgcg agatatgcat catggggatg tactgattga
    25261 caatgaaggg tacggtcaat acaaaggaga aacacaaatc gccttgaagg atatgaaaaa
    25321 cgacggacgt gtcaatgttg taggaagaat ctccgatgac gaattattcc tccttgactt
    25381 tttgaaacca tggtcaagct ttaaattaat tgaaaataaa aaatagataa ttagttattg
    25441 cagaaataat ccgctagaaa t
//
LOCUS       DACBYO010000033        24811 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.033, whole genome shotgun sequence.
ACCESSION   DACBYO010000033 DACBYO010000000
VERSION     DACBYO010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.033"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            141..572
                     /gene="mraZ"
                     /locus_tag="IVD26_001342"
     CDS             141..572
                     /gene="mraZ"
                     /locus_tag="IVD26_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAP6079329.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            593..1552
                     /gene="rsmH"
                     /locus_tag="IVD26_001343"
     CDS             593..1552
                     /gene="rsmH"
                     /locus_tag="IVD26_001343"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAP6079330.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            1557..1958
                     /gene="ftsL"
                     /locus_tag="IVD26_001344"
     CDS             1557..1958
                     /gene="ftsL"
                     /locus_tag="IVD26_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAP6079331.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            1959..4151
                     /locus_tag="IVD26_001345"
     CDS             1959..4151
                     /locus_tag="IVD26_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAP6079332.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            4177..5139
                     /locus_tag="IVD26_001346"
     CDS             4177..5139
                     /locus_tag="IVD26_001346"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAP6079333.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            5153..6514
                     /locus_tag="IVD26_001347"
     CDS             5153..6514
                     /locus_tag="IVD26_001347"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAP6079334.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            6540..7628
                     /gene="murG"
                     /locus_tag="IVD26_001348"
     CDS             6540..7628
                     /gene="murG"
                     /locus_tag="IVD26_001348"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAP6079335.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            7643..8863
                     /locus_tag="IVD26_001349"
     CDS             7643..8863
                     /locus_tag="IVD26_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAP6079336.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            9019..10344
                     /gene="ftsA"
                     /locus_tag="IVD26_001350"
     CDS             9019..10344
                     /gene="ftsA"
                     /locus_tag="IVD26_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAP6079337.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            10367..11608
                     /gene="ftsZ"
                     /locus_tag="IVD26_001351"
     CDS             10367..11608
                     /gene="ftsZ"
                     /locus_tag="IVD26_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAP6079338.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            11625..12302
                     /locus_tag="IVD26_001352"
     CDS             11625..12302
                     /locus_tag="IVD26_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAP6079339.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            12316..12915
                     /locus_tag="IVD26_001353"
     CDS             12316..12915
                     /locus_tag="IVD26_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAP6079340.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            12930..13217
                     /locus_tag="IVD26_001354"
     CDS             12930..13217
                     /locus_tag="IVD26_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAP6079341.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            13266..14048
                     /locus_tag="IVD26_001355"
     CDS             13266..14048
                     /locus_tag="IVD26_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAP6079342.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            14069..14776
                     /locus_tag="IVD26_001356"
     CDS             14069..14776
                     /locus_tag="IVD26_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAP6079343.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            15038..17836
                     /gene="ileS"
                     /locus_tag="IVD26_001357"
     CDS             15038..17836
                     /gene="ileS"
                     /locus_tag="IVD26_001357"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAP6079344.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(17885..19411)
                     /locus_tag="IVD26_001358"
     CDS             complement(17885..19411)
                     /locus_tag="IVD26_001358"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAP6079345.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(19426..20073)
                     /locus_tag="IVD26_001359"
     CDS             complement(19426..20073)
                     /locus_tag="IVD26_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAP6079346.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(20257..20586)
                     /locus_tag="IVD26_001360"
     CDS             complement(20257..20586)
                     /locus_tag="IVD26_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAP6079347.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            20763..21491
                     /gene="sfsA"
                     /locus_tag="IVD26_001361"
     CDS             20763..21491
                     /gene="sfsA"
                     /locus_tag="IVD26_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAP6079348.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            21507..22520
                     /locus_tag="IVD26_001362"
     CDS             21507..22520
                     /locus_tag="IVD26_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6079349.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            22520..23797
                     /locus_tag="IVD26_001363"
     CDS             22520..23797
                     /locus_tag="IVD26_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP6079350.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            23860..>24811
                     /locus_tag="IVD26_001364"
     CDS             23860..>24811
                     /locus_tag="IVD26_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP6079351.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAK"
BASE COUNT         8392 a         4292 c         5323 g         6804 t
ORIGIN      
        1 taaaaggctt tttgcagctt gatttttaaa aaaatgttta tgaataaaaa aagttgttcc
       61 cggatttccc agaaaaggtg gtagaaagtg ggggattgtg gtagactaat tttagttagt
      121 ggaggaatgg ggggctttca atgttgatgg gtgaattcca acataatatt gatgcaaaag
      181 gacgtttaat cgtgccctca aaacttcgtg aagaacttgg cgaaaagttt gttctgacac
      241 gcggattgga tggctgtctt ttcggctatc cgatgagcga atgggaaaat ctggaagcta
      301 aactgaacga aatgccgttg gctaaaaaag acgcacgtac ttttgtgcga ttcttctatt
      361 cggctgccac tgaatgcgaa cttgataaac aaggacgaat caatataccc agcacgttaa
      421 gaaattatgc agctttgaca aaaggttgcg tagtcatcgg tgtatctaac cgaattgaaa
      481 tttgggatga gacacgatgg caagattttt ctgcagcagc agaagagaac tttgacgaaa
      541 ttgctgaaag tatgattgat ttcggactat aagaatagga agaggctgac taatgactga
      601 aacatttcaa cactatacag tcatgttgaa agaaacggta gatggattga acatcaaacc
      661 ggatggcgtt tatgtagact gtacactcgg cggtgccgga catagtgaat atttattaag
      721 ccaactaagt tctaaagggc atctgtatgc gtttgaccaa gatcaaaaag caatcgatca
      781 cgccaagctg cgtttagctt cttatgtcga acaaggtatg gtcacattta tcaaagcgaa
      841 cttcagagaa ttagaagaac gcttgagtga gcatgtagat aaggtagacg gcattttgta
      901 tgatctaggg gtttcctctc ctcagctaga tgaagcagaa cgtggattta gttatcatca
      961 agatgcaccg ttggatatgc gcatggatca gtcagctcct ttatccgctt atcacgtaat
     1021 taatgaatat tcctaccatg aattagtaaa gattttcttc cgctatggcg aggagaaatt
     1081 ttccaaacaa attgctcgtg aaatcgaacg agtacgaaaa acaaaaccaa tccaaacaac
     1141 tggtgagctt gtcgaaatca ttaaacaagt catcccagct cccgcaagaa gaaaaggcgg
     1201 gcatcctgca aaaagaattt ttcaagctgt gcggattgca gtaaatgacg aactcggtgc
     1261 cgaagaggcc tctttagaac aggcaatccg gttattgaaa gtcaatggaa gaatcagcgt
     1321 aatcacattc cattcattgg aagacagaat tgtcaaaagt atgtttaaag aatatagtac
     1381 ggtacaagat ctaccaccgg gacttcctgt catacctgac gaattccaac cagaactgaa
     1441 agtcattact cgtaaaccaa tccttccttc agaggaagag ctaacagaaa acaatcgatc
     1501 acgcagtgca aagttacgta ttgcagaaaa aataagaatg aaagaggagt agaatgatgg
     1561 cagaattaaa gaaaatgcaa gattacgaat atgatttacc tgaattggtg gatcagccgg
     1621 aacaacaaat gcctgattct tcttcgaatc aagaaatcat tcttccacaa tcaccggcaa
     1681 aacgattaaa gcagatttct gctttggaaa aaattgctgt ggcaagcgtg gcgattgcta
     1741 ttgttgcttt atgtgtttta acagttatgc tgcgcacaaa tatcagcgga gctgaaaaag
     1801 aaatcacgtc aatacaaaca gaaatcaatg ataaaaagca agaaaaaacg agtttagaac
     1861 aagaaaaaaa cgaactttct cgtactgaac ggattaaaca aatcgcagaa gaaaaaggat
     1921 tgtctattaa tgacgacaat ttaaggaaag tgaagtaaat gagtcttaaa aataaaattc
     1981 ggcggtttat ggaaaagaaa aatctaaatc cgatgaacaa tcgcaaaaaa gtaggtatca
     2041 ttttatttgc tacgagtatt ggattgttct ttttatttgc cgtccgtttc tcgtatatcg
     2101 ttattggagg tcatgttgct ggtacctcat tagctgaaaa aacaaaacag ttgtaccaag
     2161 gaagtgaagt agtaaaagca aaaagaggaa cgatttatga tcgtaacggt gtggcgctcg
     2221 cagaagatgc ctcctcttat tcaattaaag cgatactctc aaaaacatat acctctgggg
     2281 ataaaaaact gtatgttgaa gaaaagaatt ttgataaaat agcagaaatc ctgcataaga
     2341 atctttctat agacaaaaaa gatgcactga atattttaga ggacggcgca aaaaaagagc
     2401 tgtatcaagt tgaatttggt agctatggga aaaatatctc ccaagaaacc aagcaaaaca
     2461 tcgaagcgga catgaaaaaa gaaggtgtcg ctggtcttta ttttgtcgac catcaggctc
     2521 ggatgtatcc aaatggcgtc ttttcttctc attttattgg atacgcagtt ccagacaaag
     2581 atgagaatgg cttagttggt aaactaggtt tggagtctgc ttacaatgat atcttgagcg
     2641 gtaaagatgg taagattatt tatcaaaaag ataattttca aaatcctctg ccaggtacag
     2701 tggcagaaga agaaaaagct gtcgacggac aagatatcta cacgacttta gacagcagac
     2761 tacaaagtta tttagaaaca ctgatggatc aagtaaatga agaatatcag ccagaagaat
     2821 tgacagcagt cctgatgaaa gcaaaaaccg gagaaatctt ggcaatggga caacgaccta
     2881 ctttcaatcc tgaaacaatg gaaggattga ctggaaaaga tgctatctgg cgtaatttct
     2941 tggtacaaga tagttatgaa ccaggatcaa ccatgaaagt tttcactact gcagctgcta
     3001 tcgaagaagg agaattcaac gagaatgaaa ccttccaatc tggaaaaatc caagtagaag
     3061 atgctacgat caatgaccat gactttggtg aaaaaggtgt gctgaccatg cgtcaagctc
     3121 tttcatggtc aagtaacgtc gggatggtca tactggaaca gcgattaggc ggacgatggt
     3181 ataactattt acaaaaactg ggatttggac aaagtactca ttctggatta gatgatgaag
     3241 taaacggtgc tttacctaca ttaaatattg tcgaccgagc aatgagtgct tatggacaag
     3301 cggtaggtgt gacgaatttc caaatgatga aagctttcac ttctattgcg aataacggta
     3361 caatgattca acctcgatat atcagcaaag tggtggatcc ccaaactgga gaagagcgaa
     3421 caactcaaac agaagttcta gggcaacctt tttcaaaaga aacaacagaa aaagtccgtg
     3481 aatatatgag agatgttgtc gaaagcgaaa actacggtag tgcttatggt gtatatagtg
     3541 tacctggata caatgtatcg gcaaaaaacg gaacagccca aatcgcttct gatacagggg
     3601 gatatcaaac aggagataca gcctacctgt attcgattgt ggagatggtt ccttctgaag
     3661 atccagacta tgtcttgtat ctaacaatga aacaccctaa gacatatgat cgaatggcat
     3721 tggctaaaat cgcaaatcca ttgatgaaac gggcaatgga ttttaaagaa actgaagaag
     3781 attcagatac agaaacaaaa acagaaaaag tatccgtagc cgattatcgt aatcttgaag
     3841 cggacgttgc agcagctgat gctcaaaaaa gtggactgca acctgtagtg atcggtaatg
     3901 gtaaaaaagt acaaaaacaa tctactgcca acggtgatca gttgatctct ggagaaaaac
     3961 tgatcctata tactggtggt gataagctga tgcctgacgt aacaggatgg tcaaaagcag
     4021 atatcatgaa gctggggaaa atcctcggta ttgaagttag ttttgatgga gatggttatt
     4081 gtgtcaaaca agaacttgct ccatatgaaa aaatcactga agacaaactt agttttactt
     4141 tagaagaata agaagagaaa taggagagaa aagagcatgg aatggacaca agcattgatt
     4201 cccattgtca gcagttgtgc aatgacaatt gccgcaatgc cgctatttat tggttatttt
     4261 caaatgaaaa agcaaggtca ggcgattcgt gaggagggac caaagtggca caatagcaaa
     4321 gccggaactc ctacaatggg cggcttagtg tttctgatcg gctctatttt gacaggaatt
     4381 tgggttggag cttggcaaaa acagctaact cctactcttt tcatcttgct ttttgtatta
     4441 gcgttatacg gagtaatcgg ctttcttgat gattttataa aaatattcaa gaaaagaaac
     4501 atgggactga actcgaagca gaaattgatt ggacagattc tagggggaat catcttttat
     4561 cttgtttacc gttctgaagg ttatccaggt gtattgaatt tcttcggact agatctacct
     4621 ttaggaatca tttatggtat tttcgctctc ttctggcttg ttggattttc aaatgcagta
     4681 aatctgacag atggcatcga tggattagtt gctggcttag gaagtatctc ttttgcagct
     4741 tacggtctaa ttgcttggca tcagcatcag tatgatgtat taatcatttg cttaagtgtt
     4801 ttaggaggtt tactgggttt cttcgtctac aacagaaaac ctgccaagat ttttatggga
     4861 gatgtcggtt cattagcgtt gggcggactt ttagcggcaa tttctataat gctaaaccaa
     4921 gaatggacat tgcttttgat tggtttgatc tatgttatgg aaacagcaag tgtgatgctt
     4981 caagttactt cctttaagct tacaggaaaa cgaattttta aaatgtctcc aattcatcat
     5041 cactttgaaa tgtgcggatg gtcggagtgg aagattgata cagttttttg gttgatcagc
     5101 attgtgactt cgttgatcac attatggatc gtttggtagg agatgacggg aaatgaaaaa
     5161 aatatcaaca tatgaaaata agaaagtgct tgtcttagga ctcgcaaaaa gcggagtaag
     5221 tgcggccaaa ttattacatg aattgggcgc acttgtcacc gttaatgatg gaaaaccttt
     5281 tgacgaaaat ccggaagcac aagagctgct ttctttaggg ataaaagtaa taacaggtag
     5341 tcatccaatc gaattgttgg atgaagaatt ttcattgatg gtcaaaaatc cagggattcc
     5401 ctacagtcat cctttagtag caaaagccca agaaatgggt attccggtaa ttacggaagt
     5461 tgagctagct tacgaagtag cggaatgccc aattattggg attacaggaa cgaacggaaa
     5521 aacaacgaca acaacgatga caggactact actgaatgca ggagcagatc aaggaattgc
     5581 acgtttagcg ggtaatattg ggtatccagc aagtggtgta gcgcaagaag caaaatcaga
     5641 agataaaatt gtgatggaat tgtctagctt ccaactcatg ggaatcacag atttccgccc
     5701 tcatatagcg gtgattacca atatctatga agcacatatt gattatcatg gtacaagaaa
     5761 agaatatgtc aaagctaaat ggaaccttca aaaaaacatg acagaaaaag attatctgat
     5821 ccttaactgg aatcagtcag aactacaaga attagcgcaa agaacaaaag cacgcgtact
     5881 gcctttctcg acaaaagaag tgttggaaga cggtgtgtat gctgacgatt actcaatata
     5941 ctataaaaaa gaaaaaataa tggaaatatc tgaacttggc gtaccaggta agcataatgt
     6001 agaaaatgca ctagctgcta tttctgtagc aaaattgtat ggtatatcaa atgaagctat
     6061 acgagaaacg ttgcattttt tccatggcgt accacatcgt acgcaatatg taggagaaat
     6121 ccaaggcaga aaattttata atgattcaaa agcaaccaat attttagcga ctaaaatggc
     6181 tctaagtgga tttgaaacgt ctaaggtcgt gttattggct ggcggattag acagaggaaa
     6241 tacatttgat gaattaattc cttcattaaa aggaatcaaa gcaatggtcg tatttggcca
     6301 aacaaaagaa aagttgatgg atgctggaaa aaaagcaggc atcgagacaa tagtaacagc
     6361 cgattctgta gaacaagcag ttcctttagc attagaaaac agtacagatg gtgatgtagt
     6421 tttattatca ccagcgaatg ccagctggga tcaataccca aattttgaaa ctagaggaaa
     6481 cagattcatg gaagctgtga accgattaaa atagaaaaag tagaagcgag cgataaaaaa
     6541 tgaaaatttt ggttacaggc ggaggaacag ggggacatat ttatccagct cttgcctttg
     6601 tcaattatgt aaagactcaa gaaccgaatg ctgaattcat gtatgtggga gcaaaacgag
     6661 gtctagaaaa caaaatcgtc cctgatacag gaatgccttt ccataccttg gagattcaag
     6721 gatttaaacg aaaaatttcc atgcataaca tcaagacggt ccgattgttt cttaagagta
     6781 tccgtcaagc aaaaaaaatc ctcagtgatt ttcaaccaga tatcgttatc ggtactggag
     6841 gatatgtttc cggagcggta gtgtacgctg cagccaaaat gggtattcca acagttatcc
     6901 atgaacaaaa cagtgtacca ggtgttacca ataaattttt aagccgatat gtggatcgga
     6961 tcgctctttc atttaaagat gcggcttcct tttttcctga aaacaaagca gttcttgtag
     7021 gtaatcctcg agcacaagaa gtagcagata ctaaaaaatc agatattttg aaaacatttg
     7081 atttggatcc agaaaagaaa acagtcttga tttttggcgg tagtcaagga gcacttaaaa
     7141 tcaatcaagc agtatcagtt tttttaagtg aatatattcc ttcttcttac caagttttgt
     7201 atgcttcagg agatagatat tatgaagaga tcctaaataa aataaatcct gaaatacaaa
     7261 atattagtgt ccagccttat atcaaaaata tggcagaggt catggcttcc agtgatctgc
     7321 tggtggggcg tgctggtgca acttcgatcg cagaattcac agctctgggg ttaccggcag
     7381 tgttggttcc cagcccatat gttacgaatg atcatcagac taaaaatgca atgagtcttg
     7441 ttcacgcagg agcagcaaaa atgattgcag ataatgaact aacaggtgaa tcactaagtc
     7501 agacagtcaa cgaaatcatg ggtgatgaag aattgcaaaa gcaaatgtgc cgagcttcta
     7561 aagaacaagg aatccctgat gcttcaaaac gtctttatga cttagtaaaa caaataatca
     7621 aaaaataaag gcggtggtct tagtgagtaa gaaaaaagaa ccaaaaaaat tgtctcatcc
     7681 gtcttctgat gaaaacaatt tgactccttg gcaaaaggct aaccgaaaat atctggcaga
     7741 acaagagatg aaaaaccaag agccaaaaaa agaagacata acattagata cacccctttc
     7801 agattctgaa gaagaaaaaa cggttcaaga ggaacagcaa gaagaaagcc agtccgagaa
     7861 aaaaatcgaa ttttttgaag agatcaagca aaagaaaaac ggtggaccat ataacggttc
     7921 ttttttgaac cggctgccca atttaaaaag tcaacggcac aaagtactat ttcgtcggtt
     7981 agctttgatc atcactgtat tgggtatacc gctgattttt ttgatctatt atgtttctcc
     8041 ttatagcaaa ttacaagcag ttgcagtatc aggcaataag acagtcaaca gccaagaaat
     8101 catctctgat acaaaattgt cattaggaga aaatgtttgg ggacagtatt ttcatcgatc
     8161 tacttatatc gatcgcctta aaaaagcaca gccaagaatc gaaacagcaa atatacattt
     8221 caaagggatg aatgaattcg atttggatgt aacagaatat aaagagattg ctttgatcgc
     8281 aaaaaacaat caatactacc cagtgattga aaatggaaca gtattagatg aaaaagtagc
     8341 aaatcctaca aaaaatctcc ctatcttgga agagttcaaa gactctgcaa aaatcaaaga
     8401 attaacaaag caatacaatc agttatcatc agaattacaa aaagcaattt ctgaaatcaa
     8461 gtacacgcca agagcaagca ataaaaatct gatccaattg aatatgaatg acggcaatca
     8521 agttattgta aatatcaata atcttgcgaa ccaaatgaaa tattattcgc aagtagccaa
     8581 agatatggat gaaaaaggtg tgatcgacat ggaagttggt atcttctcgc atccttacgg
     8641 tagcactcaa gaaacggaag aatcgggcca atcggaagaa acaactgaaa gtgaagaaaa
     8701 tgcggatcaa acaaacgaat caagtgaaga ggcagaaacg caaaaagcac aaacacctgg
     8761 atcgtctagc acaaacggat catctgattc aaatgattca agtgaaacaa gtcaaataga
     8821 agataatcca agtacaactc cgtcaagttt aaatgaaaat tgataaaaca actttaaaaa
     8881 gtaagaatgt actttctaaa aaccagtaat ttatggtaga attggaagca gtgaatatat
     8941 ctattaataa gtatatttta aaacggacgc tagttgttcg cttgtatatg gaatagtaag
     9001 taggagggaa tcccattcat ggcaaaaaca ggaatgtatg taggccttga tattggaacg
     9061 acatctgtta aagttgtcgt ggctgaatat atcgacagcc aaatgaatat tattggagta
     9121 ggaaacgcaa aatcagaagg gattaaccga ggcattatcg ttgatatcga taaaacggtc
     9181 caagcgatac aacgagcagt acgacaagca gaagaaaaag caggtatcca gatcaaaggc
     9241 gtaagtgtcg gtttgccagc aaacatgctt gaagtagaaa attgccaggg aatgattgca
     9301 gttaacggag attcaaagga aatcaccgat gaagatgtca gaaatgtggc ttcagctgcc
     9361 cttgttcgtt caatacctcc tgaacgtcaa atcgtgtcaa tattgccaca agattttact
     9421 gtcgatgggt tcgagggaat caaagatcct cgtggaatga tcggcgtaag attagaaatg
     9481 tacggtctgt tgtttacagg acctaaaacg atcatccata acatacgtaa atgcgtggaa
     9541 aatgccggat taatcgtcaa cgaaatggtg attactcctt tagcgctgac tgaatcaatt
     9601 ctttctgacg gagaaaaaga ttttggtacg atcgtcattg atatgggtgg cggccaaaca
     9661 acaacggctg ttatgcatga taagcaattg aagtttacca atcttgacca agaaggtggc
     9721 gaatttgtca ctaaagatat ctctattgta ttaaatacgt catttaacaa tgcagaagcg
     9781 ttgaaaataa actacgggga tgcataccca gaacggacat caccagatga agaatttcca
     9841 gtagatgtga ttggtcagtc agaaccagtg aaagtcgatg aacgctactt gtcagaaatt
     9901 atttcagctc gaatggaaca gattttcaac aaagcaaaag atgcattgga ccaaatcgaa
     9961 gcattagagt tgccaggtgg cgtcgtattg acaggcggag ctgctagtct tcctggtgtt
    10021 gtggacttgg cacaagaaat cttcggcgta aatgtaaaat tgtatgttcc aaatcacatg
    10081 gggctgagaa acccggtatt tacaaatgta ataagtatcg tggattattc agcaaacttg
    10141 agtgaagtgt atcaattggc aaaaattgct gttacgggtg aaacctcagc agctcgtcaa
    10201 atggtagttg aacaagaaac aacaaacaca tatgagagct atgaagcacc tgaagaaaca
    10261 atctacgatg agccggaacc aaaagagtcc ggagaaaatg taaaaaataa aatcaagggt
    10321 ttctttacaa atatttttga ttaattcatc ctgggaggaa taagatatgg aattctcaat
    10381 tgataataat atcaatgacg gcgcagtaat caaagtcatc ggagtcggtg gtggcggtgg
    10441 aaatgctgta aaccgaatga ttgaagaaaa cgttaaaggt gttgaattca ttacagccaa
    10501 cacagacgtg caagcattaa aaaattcaaa agctgaaaca gttatccaat taggccccaa
    10561 atatactcgt ggtttaggtg ctggttctca gccagaagtt ggacaaaaag cggcagaaga
    10621 aagtgaacaa tccttacgcg aagctttaga cggtgcagat atgattttca tcactgcagg
    10681 aatgggtgga ggaaccggta caggtgctgc accaatcgtt gcaggtatcg cgaaagaatt
    10741 gggcgcattg actgttggtg tcgtgacacg tccattcact tttgaaggac cgaaacgtgg
    10801 ccgttttgct gcagaaggta tcgctcgttt gaaagaaaat gtggatacat tattaattat
    10861 ctcaaataac cgtttattag aagttgtaga taaaaagaca ccgatgcttg aagctttccg
    10921 tgaagcagat aatgttttac gacaaggtgt acaaggtatc tctgatttga tcacagcgcc
    10981 aggttacgtt aaccttgact ttgctgacgt gaaaacagtg atggaaaacc aaggtacagc
    11041 attgatgggg atcggtgtgg ctagtggaga agatcgcgta gtagaagcaa cgaaaaaagc
    11101 aatctcctct ccattgcttg aaacatctat tgatggagct gaacaagtac ttcttaacat
    11161 cacaggcggt ttggatatga cattgttcga agcacaagat gcttcagata tcgtagcaaa
    11221 tgcagcaact ggcgatgtaa atatcattct aggtacatct atcaatgaag aaatgggcga
    11281 tgaaatccgt gtgacggtca tcgcaacagg tatcgatgaa tcaaaaaagg aacgcaagtc
    11341 tagccgacca gctagacaag cacaaatgca atcacctgct caaaagactg tattagatat
    11401 ggatcaagct aaaccaactt cttcagaaga agaaaacagt tttggcgatt gggatatcag
    11461 acgtgaacaa aatgttcgtc ctagagttga tgattccaat tttgacaata tcgaaaaaaa
    11521 agaatttgat acattcaacc gcgaagaaac aaaatctcat ggcgatgatg aattaaatac
    11581 gccaccgttt ttccgtcgta aaaaataaag gagaggaaga gcacatgatt gctgacaact
    11641 tgcagaaaat caagcaagaa attcaggatt cgtgtgctct tgttcatcgt gatccgaaag
    11701 aagttacatt agtagctgta acaaaatctg ttgaatccgc tcaagctgaa gaattggtta
    11761 gagctggcgt tatgaattgt gcagaaaacc gagtagataa attattagaa aagaaacaag
    11821 atttatttga ttttcctgaa ataaagtggc atttaattgg taatttacag cgcagaaagg
    11881 taaaattgat tgtaaatgaa attgattact ttcatgcgtt ggacagttta agattagcag
    11941 aagaaatcca gaagcggtta gagaaagaat tatcctgttt tattgaagta aatgtttctg
    12001 gtgaggaatc aaaacatgga atttcaccag atgagctttt accgtttgtg gaatctttag
    12061 ctgcctgcac aaaaatcaag gttgttgggt tgatgactat ggcgcctaaa gaagcttctg
    12121 atgagcaaat ccataaagtg tttggtacgc tgaaagaatt gcgtgatctt gttcaagcaa
    12181 aaggttatgc ccatgcacca tgtagtgaat taagtatggg gatgagtcaa gactttcaaa
    12241 ttgcgattga agaaggtgca acatttatcc gtgtaggaac agcgctattc aaagacgaat
    12301 aaaggaggaa caaaaatgcc gcttttaaac agaggagcaa ttgctaattt tttcggatta
    12361 gctgatgagg aagagtacga ataccaagat tatcctgaaa caacaaaaaa ggctgtacag
    12421 ccaactaaaa aaaatacaac acagaatcaa tcaactcatt ctgtatctgc tgcgaatact
    12481 catgaaaaac aaaaaacggc gacttcacgt cctgtaacgc atgaaagtat tcagccggct
    12541 gaaaagaaaa aagtaattga actacatcaa tcacctacaa aaactgtagc gaaagaaaga
    12601 acagcttcaa gaacctctac acaacctaaa gcaaatcttg ctggaaaaat cactgtaatg
    12661 gaaccaagag cttattctga agctatggcg attgctaaac gaatcattgc tggagaagca
    12721 accttagtga attttcattt agtagaagaa aaacaagcga gaagaatcgt tgattttcta
    12781 acaggaacag tttatgcact agatggagat atcaaacgtg ttggagatga gatttttctt
    12841 tgtacaccga ctgggatgga gattgacagt tcaaccgctc aatcttttgc agatgcgaat
    12901 ttgtttgatc tgtaagagga ggaactacga tttatactat tgcactatta cttcatttac
    12961 ttcaacgggc agcctatttc tatagcatta tcttgatggt atatgcattg ctctcttggt
    13021 ttccaggcgg gtatcaatca gggctaggac gattattagc taagatctgc gaaccgtata
    13081 tcagtttgtt cgatcgtctg cctttgagga ttggaccctt ggatttcaca attttagggg
    13141 caatcctgat cttgaactta gccgtacaag gtttagcaca gatcgttata tggataactg
    13201 tccatttagt ttattgattg aagcaacaaa atctttattc tcagaataga taggagggga
    13261 aaattttgga tgcaaatgta taccagcact ttcgggcaga tgaacgtaca tttatcgatt
    13321 cggtaggcga ttggattgaa caggttcaag gacaatatgc accctatctg accgaatttc
    13381 ttgacccaag acaatcctat attttagaaa cactgattcg acaaagcagt gatttgcgtt
    13441 tcatgtttta tggcggatat gaacaggcag aaagaaaaag atgtttgatt ttccccgatt
    13501 attacgaacc tgtagaggaa gattttgaaa cagcattgta tgaaatccat tatcctagca
    13561 aatttgccag cctaagtcat gggaaaatcc ttggaacttt agtgggaacg gggatcaaac
    13621 gctcttactt tggcgatatc atctcggacg gtgatcgctg gcaagtattt attgcaaatg
    13681 aggtggatca ttttgttgct gcacaagtaa caaagattgg aaaggttgct gtacgcttgg
    13741 aaccaatcaa atacacagaa atgattatgc cgaaagatag ctggacacaa gaaagaggaa
    13801 cagttagttc catgcgacta gacagtgtga tctctgagat ttataatatt tccagacagc
    13861 ggtccaagca gctgatcgaa gctggtaaag taaaagtgaa ctggacagaa aatacaagac
    13921 ctgattttgt acttgaacta ttagatatta tttcagtcag aggttatggc agagtccaga
    13981 tccaagaact tgaggggaag acgaaaaaag aaaagtacag ggtactgttc ggtgtattac
    14041 gtaaataaaa taaaaaggtg gtttactcat ggctttaact ccattagata tccaaaataa
    14101 gacattcccg acaaaaatgc ggggatataa tcaagacgaa gtagatgatt tcttagattt
    14161 agttgttcgt gactatgagg aattgactca aagaaatcga gaattagaaa aagcagtcaa
    14221 acattctgaa gaaaaacttg agtacttcaa tgaattaaaa gatgctttga accaatcaat
    14281 catcgtagct caagatacgg ctgataaagt aaaaacaagt gcaagcaagg aatccgaagt
    14341 gatcgttact tctgcacaaa acaaagcaga tgagttagtt gcgaacgctg aaaaacgtgc
    14401 acatcaatta acaactgatg cagaagaaaa agcaagaaaa atcttgacag atgcaacaga
    14461 aaaagcaaga cagcttgcga cagaaactga agatcttaag aaaaaaacac gagtattcca
    14521 tcaacgtatc agcttgatgc ttgagtctca attagaacaa gtgaaaagtc cggaatggga
    14581 tgaaatttta caaccattct ccagctacgt gactgacagc catgaagtga tcaaagaagt
    14641 tttagcaaaa cagcttgaca atgaaaatga tactgatgta aactcagaca caggagtcat
    14701 agaagcacct atgacggcat ttgatacaca ggctattgat atctcgatcg tgcctggtga
    14761 aaatgaaaac gagtagaaca gaaaagcact ttgttattct taaagcgagc cgatgagagt
    14821 ggaagttcgg taagacactg catggtgaaa gatcctctac ttgagacctg cttttccgaa
    14881 attagagtaa gaagcagcgg ctgacctcgt tattggtcac agagagtttg cactagatag
    14941 atgcaactaa atttgggtgg taccacggca tgttcgtccc ttgcggctga acatgctttt
    15001 ttgtgtccgg aaaacaaata aaggagtgta tggttgaatg aaaatgaaag aaaccttgca
    15061 attaggaaaa acaaaattcc ctatgcgtgg taatttgcca aaccgagaag gcgagtggca
    15121 aaaagaatgg gaagaaaatc gaatctacca aaaaagacaa gagttgaacg aaggaaaacc
    15181 tagctttgtt cttcatgatg gacctccata tgccaatggt aatatccatt taggacattc
    15241 attgaataaa atcagtaaag acattatcat tcgttcaaaa tcaatgtctg gctatcgtgc
    15301 accatatgtt ccaggatggg atacacatgg attgccgatt gaacaagtat tggctaataa
    15361 aggcgtgaaa cgtaaagaaa tgtccatggc agaatacttg gaaaaatgtc gtgaatatgc
    15421 actttcccaa gtagataagc aacgagcaga tttcaaacgc ctaggagttg caggagattg
    15481 ggaacatcct tatgttacat tagatccttc ttatgaagct gcacaagtac gcgtatttgg
    15541 taaaatggct gaaaaaggct atatttacaa aggattgaaa ccaatttact ggtctccgtc
    15601 aagtgagtct tctttagcgg aagctgaaat tgaatataaa gatgtaaaat ctccatctat
    15661 ttttgtagct ttcaatgtca aagacggcaa agatattctt gatgaagata cagcttttgt
    15721 catttggacg acaacaccat ggacattgcc agcaaaccaa ggtattgctg taaatccaaa
    15781 atttacgtat gtattggtgg aagccgatgg ccgtaagttt gtcgtagcga aagatttgct
    15841 agaaacagtc caatcagaaa tcggttggga aaatgtaaca gttctaaaag aatttgctgg
    15901 acaagaaatg gaatatatga ctgcaagtca tccattctat gaacgtgaat cacttgtgat
    15961 tttaggcgat catgttactt tagacgctgg tactggatta gtccatactg ctccaggaca
    16021 tggggaagat gactatatcg ctggtagcaa atataaacta tctgtagtgt cacctgtaga
    16081 ctcaaaagga ttgtttacag aagaagcacc tggatttgaa ggtatctttt atgacaaagc
    16141 aaatcctatg atcactgatc tattaaaaga aaaaggagct ttgctgaagc tagatttctt
    16201 tactcatagt tatcctcacg attggcggac gaaaaagcct gtgatctatc gggcaactcc
    16261 acaatggttt gcatctatcg ataaattccg tcagaatatt ttggatgaag tagaaaaagt
    16321 agagtgggtt atcccatggg gtaaaacacg tttgtataat atgatccgtg accgcggcga
    16381 ttgggtaatt tcccgtcagc gtgcatgggg agtaccactt ccgattttct atgctgaaaa
    16441 tggagaagca atcatcacac cagaaacaat cgaacatgtg gcaaaattat ttgctgaaca
    16501 tggatcaatt atctggtttg aaaaagaagc gaaagaactt cttcctgaag gatttaccca
    16561 cccaggttct cctaatggcg aatttacaaa agaaaaagat atcatggatg tctggtttga
    16621 ttctggttct tctcatgaag ctgttttacg tcagcgacca gaattatcat tcccagcaga
    16681 tatgtattta gaaggatcag accaatatcg tggctggttc aactcaagta tcacgactag
    16741 tgtggctatc aatggtgtag caccatacaa atcagttatt tctcaaggat ttgctttaga
    16801 tggtgaaggc cgtaagatga gtaaatcttt aggaaacatc attgcaccag aaaaagtgat
    16861 caaacaattt ggtgcagata tccttcgctt atgggtatct agtgtagatt atgaagcaga
    16921 tgttcgtgtt tctatggata tcttaagtca agtggcagaa gtatatcgta aaatcagaaa
    16981 tacgatgcgt ttcttattag cgaatacaga agatttcgat cctaaaaaag atactgtttc
    17041 gtacaatgat ttacgttctg tagacaaata tatgaccgtt cgattgaacc aagtaatcaa
    17101 agaaatccga gaagaagggt acgacaaata taacttcatg catatttacc gtacagttat
    17161 gaacttcttg acggttgatc tatcgtcatt ctacctggat tttgctaaag atgtagttta
    17221 tattgaagca gaagatgatt atcaacgtcg ttgcatgcaa actgttttct atcaaacagc
    17281 tgtagctttg acaaaattat tgactcctat cattccgcat acagcagaag aaatctggtc
    17341 attcctgaaa gaagaagagg agtacgttca gttaagcgag tttcctggtt atgaagagtt
    17401 tgcaaaccaa gaagaattga tggatacctg gactgctttc atggacttcc gtgataatgt
    17461 cttaaaagca ttggaagaag caagaaacag caaattgatt ggtaaatctt tggaagcaaa
    17521 actaactgtt tatccaaaac aacaagttcg tgaaatgtta aaagctttgg atgcagatat
    17581 tgcacaatta ttgatcgttt caccagacta ctttgaagtt atggcagcag atgaacaagt
    17641 gccagataac gctatggtat ttgatgatgt tgctattaca gtggaaaaag cagacgggga
    17701 aacttgcgat cgctgtcgcc aagttcgtaa agatgtagga gtagatgaaa aacttcctca
    17761 tctatgcggt cgttgtgcaa aaatcgttga agacttctat cctgaagctg tagctgaagg
    17821 attcgaagaa aagtaaaagg gaaaaggggg tgtgacatgt tctttgtcac accccctttt
    17881 gttatcaatc gtttaatttt ccacgttcac gataccagtt atctggttgc cagatccatt
    17941 cgaatccgtc tttttcaagt agttcgaaag ctgctttagg tcccattgat ccagctttgt
    18001 agttgggaaa atccggttgt gtttggtccc aagcttttcg aatgacatcc acgatatgcc
    18061 aagattgagc gacttcttcc caatgagaga agttcgttcc atcaccattc aacgcatcta
    18121 atagtaattt ttcgtaagct tctgggctat tttcaaccat ttctgcacta tttctaaatt
    18181 ccaatttgat tggttccgtt tcaaatcctt gccctacttc tttcccattc aaggataaag
    18241 aaaatccttc agttggctga atatagatcg ttagaacatt aggtggaagt gtcgtatcgt
    18301 cacatggttc atcgacagat gttttgaata cattaacagg aacttgtttg aatacgatgt
    18361 tgatccgagt ccctttttca gtcaaacgtt tgcctgtacg tacatagaaa ggaacacctg
    18421 accaacggaa gttatcgata gtgaatttgc ctgcgacgaa tgtttcagtc tctgattgag
    18481 catccacttt gtcttcttcg cgatagccct tgaattgtac accatccaat tcaccttgag
    18541 catattgccc gcgaacgaag ttttctaaca cttcttcttc gttataaatg cggatagctt
    18601 tcaatgcttt gatcttttct gtacggattt ctttttcgga aaatgctact ggcggttcca
    18661 ttgcaagtaa tgctacaacc tgtaaaatat gattttgcac catgtcttta agtgcgccac
    18721 tatgatcgta gtagcccccg cgatcttcta caccgaggtt ttcgccaaaa gtaatttgga
    18781 tattgtcgat atagcgattg ttccattgag cctcaaaaat attattggca aaacggatag
    18841 ctgagatgtt ttggatcatt tcttttccta aataatgatc aatcctgaaa atatcttgtt
    18901 ctgggaatac ttctctgatt tgctggttca attcaaaagc agactggtaa tcagaaccga
    18961 acggtttttc tatgatcaaa cgattgaagc cattttttgt cataatattt tgtgatttca
    19021 aatgagaaac gatcgttcca aaaaattgag gtgccatagc caaataatag acacggttac
    19081 cgtttaattg atagtgtcca tctaatcggt cagacaattc ttttaatgtc tgataatgcg
    19141 ttgaatcatt tacatcatgg gattgatagt aaaaatggct tgcaaaggta gttgcttctt
    19201 catctgaagg attcaatgca cggattgttt ctttgacaac ttcacggtag tgctcatcgc
    19261 tccagggacg gcgagcggtt ccgattacag caaaatgctc gcctaaattt ccttttctgt
    19321 aaaggcggaa caaagacggg tacaatttac gctgggctag gtcacctgta ccgccgaata
    19381 tcgtaaacaa tacatttttt tcattagaca tgtggataca ctcctttata ttttatcgac
    19441 aaaaatcgtg ctggccgcct taaagctgac ggggattttc tttctatcat tttggatagt
    19501 gatcggtcct tcataagctg cgatgtcaac gatctcatat tcttcgttga tattcaggtc
    19561 aatagtgact aagtaatcca acaattcttt ttcatcaagc actcgtgcga tacgcacttt
    19621 tgtaccgaca ggataggact ccaatgtttg tcggcgttct tcatggacaa cttcctcttt
    19681 tttaggaatc gatcctccat gaggacaatg ttcaggatga ttcaaatagt tttctaaatg
    19741 atctgcaaga tgttccgaag tcacatgttc caatacttca gcatcatcat ggacttcatt
    19801 ccagctatag tctaaatgtt caactaaaaa aacttcccat aagcgatgtt tgcgaatcag
    19861 actgctagct ttttgcagtc cgcttgcagt caattgtaca ccttgataag gggaatgttc
    19921 tacaagctct tctttcacaa gtttagaaat catttcactg acagatgcag ctgagacatc
    19981 tagactagat acgatttgtt tattgttgac tttcgttgta tctccaccta gttctaaaat
    20041 gattttcaaa taatcttctc gatttggtgt catattcgat catcctttca tggtaaaaaa
    20101 ccatcattag taagtgtaac aaaaaaaacg ttaattgact atttttctaa ataaaaaaca
    20161 aaggattttt agacgttttt acaacaaaaa acgaaagatg atagagaaga ctcattcttt
    20221 cgtttataaa ggatatatat atacattggg agggatctat ttttcagata acaacttata
    20281 tgaagtgtct gcagattcgt cataaagagt ttgttcggga taagaaaaga taagataaaa
    20341 accatactga tcacgtacga ctaaacgata ttcatctatt tctaccacag atgtgccaag
    20401 agactgaccg ttgatcaaaa acgtgtaatc agatgtaatc tgtaattgtt gtttttgctg
    20461 gctatcacta aagaaccatg taccttgata ctttgagagt ccttctgact tttccgcttg
    20521 ttttttcttt ttcaagtaaa taaaacttga gagaacggta atgagtgaac caagaaaata
    20581 gatcattttt tttatcacca aatcactcct ttatgagaaa ataatcgcat agacatattc
    20641 tttcttcttt atttcattgt accgaataaa agctaaaatt tctctaagac tttcgactgg
    20701 tttttttact gtttttctac aaattatgat aggatacata gtaggaagaa aggtgacata
    20761 atttgaagta tcagcaagtg gaaatagctt tttttattga ccgcccgaat cggtttatag
    20821 cacattgtat gaaaaaagac ggagaaataa ttattgcgca tgtcaaaaat acaggtagag
    20881 gaaaagaggt cctgatacca ggcgctgaag tggctattgt atttgctcct ggacctaaac
    20941 ggaaaaccgc ctatgatctg attgctgtaa aaaagaaggg tgactggttt aatatcgata
    21001 gtcaattgcc taatcggctg gcaattgatg gtattttaga cggcacgatc cttttaccag
    21061 gattaactgg tccatttacg gtatacaagc gtgaagtaac ttatcttcac tccaaatttg
    21121 atatttattt agagacggtg gtcggacaaa aagcatttgt tgaagtcaaa ggtatgacac
    21181 ttgaaaataa agcgattggt gcttttcctg atgcgcccac actcagagga ttgaaacata
    21241 taggagaatt aacgtatgcc gcacaagatg gttatgccgc ttatgtcttg tttattgctc
    21301 agttcgaaca tcttcatctg gcaacgatcc atgaagaaat gcaaccagca ctagctgata
    21361 tggttcgaca tgcgcagcaa agcggagttc aaatcctcgc ctataattgt caagtatcgg
    21421 cagatgaggt aactgtcaag caggccattc catttgatgt agatatccct tttgaagatc
    21481 ctatacaata gaaagaaggt aaaataatga tcaacttagg tattatcgga acaaattgga
    21541 ttactcatca atttgtccaa gcagctttaa gcacaaaaaa atatgaattg acagcggtat
    21601 attctagaca tttggaaaaa gcacaggaat ttggttctca ttatgaaggg gatatcgaat
    21661 tcgcaacaga tttgaagact tttttcaata ttactcatat ggacaccatt tatattgctt
    21721 ctccgaatag tcttcacttt agtcaagcta agcaagcaat tttggcagga aaaaatgtga
    21781 tagttgaaaa gccagctttt tcgacgccaa aagaaatgga tgaaatcatc catttggcaa
    21841 atgaacacaa tgtgtatttt tttgaagcag caagaaatat ccatgaatca ggttttaaaa
    21901 agattgccga ttacttacca ttaaaagacg agataatcgg tgcaaatttc agctatatga
    21961 aatattcttc gcgctatgac caagtattag atggagaaga accgaatatc ttctcgactc
    22021 atttctcagg tggtgcattg atggatttag gtgtttacct tgtatatgca gctgttgctt
    22081 ggtttggaat gccaaaagaa gtccattatt tcccaagaaa gatttctact ggtgtagatg
    22141 gtcttggatg ggggatctta cgttatgaga attttgatgt atcgatccag ccaggtaaaa
    22201 tcggtgattc ttatttaccg tcagagattt attttgactc aggaacgcta gtgatgaatg
    22261 gagtcaatgc aattgaacaa gcacaatttc atgatcgcgc gcataaagaa atcattgatt
    22321 tggcggtaac agctgcagaa aatccaatgg cagatgaagc agaggatttt gccaatgtca
    22381 tggctcatcc gaaagatcca gcttggggat tgttgtatga agagtggatc gagctagcta
    22441 gaaatgtgaa ccaagtgatt tatgatttaa gaaaaaatgg cggcatcaaa ttcgatgcag
    22501 ataatgagga agatttttaa tgaacgaatt tgtacaagta tttcccgaaa attggcagaa
    22561 aaaatatgag gataaagggt ttatctcacc ttctcttatt caacgagcag tttttcagcc
    22621 actaagtaat aaacaaagta tagtagcggt ttctcctaca ggttcaggta aaacactggc
    22681 ttatctttgg cctctactac taaacgtgga accaggtgaa gcaagtgcgt tggtcatttt
    22741 tgcttcttct caagaactag ctattcaagt agcagatgtt gcacgtgaat ggggaaaaga
    22801 caaagagttg aaagtccaat ctttggtggg cggagccaac gtcaaacgtc agattgaggg
    22861 tttgaaggaa aaaccagaaa tcttgattgg tacaccagga agaatattgg aattgatgaa
    22921 agcaaaaaaa ataaaagcac atcaagtgaa aacaatggta tttgatgaag cagaccagct
    22981 atttgacgct gggaacagcc aaatcattga tcaaattctt catcaagctc caacagagta
    23041 tcagctagct tttttttcag cgacagcaga tcgttccctt gaaagcattg aaaaaatcac
    23101 tgggaaaacg tttgagacaa ttgacgtgac agcagaggac gattctcgaa aaggactgag
    23161 acattacttt ttacgtgtac cgatacgaaa gaaagatgac tacttgagac gtctcacgca
    23221 tatagaagat tttcatggtc tgattttctt taatcaactg actgaattag gcgtaatgga
    23281 agaaaaattg ctgtatagag gtgtaccggt aggaagtctg gcctctgatc agaacaagct
    23341 actccgaaaa gcagcgctag aacaattcaa aaagaaaatg gtcagagcac ttttgaccac
    23401 agatgtggcg gctagaggtt tagatattac aggtcttcct tatgtagtga atgcagaagt
    23461 tccgttaagt gaagaagctt atttgcatcg ttcgggaaga actggtcgaa tgggtaatga
    23521 aggaatagta attacactcg tacaagataa taatctaaga gatttaaaac ggcttttacg
    23581 tccatcaaat ataacacttg aagagatttt tttatacgga ggtaagctgc aaactgagca
    23641 gccaaccaaa gaagatgcag ctcctgcagt aaataaaaag tatgcgaaaa ctttttctgg
    23701 aaaggagcag aacccagaat ataacaaaga aaaaataaga aaaaaagtta aaaataaatc
    23761 aaaaaaagag agaaataaag gagcaaggcg caaataagcg cctttttatg ctatgattat
    23821 gaaaacggga acaaaattgg ttgccagagg aggggttatg tgaaagaacg tcaagaagag
    23881 atcttgcagc tattgacaga aaaccaacaa ggattgacag caagtgatgt agctgagcgc
    23941 ttaactatcg atcgaagcaa tgcaagccga tatttaagtg aactatacaa ggcccatcat
    24001 attgtaaaaa ccgctggccg accagtcgtt tactctttgc caacggaaaa gtcaaaatct
    24061 gatgaagtgc atgtcgactc ttctacgcaa gtgacttttg aaacactcgt tggagaaaat
    24121 gattctttaa aagtcagcat acagcaggca aaagctgcga ttctttatcc accgcggggg
    24181 ttgcatacga ttatttttgg agaaactggt acagggaagt cgatgtttgc tgaatgtatg
    24241 tatcattttg caatcgattc agagatgctt tctgcagatg cgccatttgt ttctttcaat
    24301 tgtgcggatt atgctcaaaa tccgcaactg ctctttggac acatctttgg gatcaaaaaa
    24361 ggggcttaca caggagcagc tcaagatagt cccggtctaa tagccaaagc agacggcggt
    24421 atattgtttt tagatgagat ccaccgttta ccgccggaag ggcaggaaat gctgtttact
    24481 ttcattgata aaggtattta ccgtccgctt ggagaaagtg cacaagtaca tgaagcatct
    24541 gttcagatca ttggggcgac gactgaatct tcagaaagtt tcttatctac gttcaatcga
    24601 cggattccta tggcaatcac cttgccgaat cttgcttcac gttcactgga tgagcgttat
    24661 gaaatcatct ctctttttat caaacaagaa gcgaatcgtt tgaatcaacg tatcgatatc
    24721 gaaaaagaag cgattcttgc cttcatgctt tatgatgcgg aaggaaatat cggtcaagtg
    24781 aaacgagact tgaaactagt ctgtgcaaaa t
//
LOCUS       DACBYO010000034        24721 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.034, whole genome shotgun sequence.
ACCESSION   DACBYO010000034 DACBYO010000000
VERSION     DACBYO010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.034"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            308..1969
                     /locus_tag="IVD26_001365"
     CDS             308..1969
                     /locus_tag="IVD26_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6079352.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2039..2386)
                     /locus_tag="IVD26_001366"
     CDS             complement(2039..2386)
                     /locus_tag="IVD26_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAP6079353.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2470..3411
                     /locus_tag="IVD26_001367"
     CDS             2470..3411
                     /locus_tag="IVD26_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079354.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3412..4455
                     /locus_tag="IVD26_001368"
     CDS             3412..4455
                     /locus_tag="IVD26_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079355.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4461..5531
                     /locus_tag="IVD26_001369"
     CDS             4461..5531
                     /locus_tag="IVD26_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079356.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5521..6474
                     /locus_tag="IVD26_001370"
     CDS             5521..6474
                     /locus_tag="IVD26_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6079357.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6486..7496
                     /locus_tag="IVD26_001371"
     CDS             6486..7496
                     /locus_tag="IVD26_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6079358.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7781..8602)
                     /locus_tag="IVD26_001372"
     CDS             complement(7781..8602)
                     /locus_tag="IVD26_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAP6079359.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8699..8977)
                     /locus_tag="IVD26_001373"
     CDS             complement(8699..8977)
                     /locus_tag="IVD26_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079360.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9245..11254
                     /gene="metG"
                     /locus_tag="IVD26_001374"
     CDS             9245..11254
                     /gene="metG"
                     /locus_tag="IVD26_001374"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAP6079361.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11733..12320)
                     /locus_tag="IVD26_001375"
     CDS             complement(11733..12320)
                     /locus_tag="IVD26_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079362.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12495..13817
                     /locus_tag="IVD26_001376"
     CDS             12495..13817
                     /locus_tag="IVD26_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6079363.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13972..14748
                     /locus_tag="IVD26_001377"
     CDS             13972..14748
                     /locus_tag="IVD26_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAP6079364.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14741..15310
                     /gene="rnmV"
                     /locus_tag="IVD26_001378"
     CDS             14741..15310
                     /gene="rnmV"
                     /locus_tag="IVD26_001378"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAP6079365.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15303..16187
                     /gene="rsmA"
                     /locus_tag="IVD26_001379"
     CDS             15303..16187
                     /gene="rsmA"
                     /locus_tag="IVD26_001379"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAP6079366.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16638..17267
                     /locus_tag="IVD26_001380"
     CDS             16638..17267
                     /locus_tag="IVD26_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079367.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17391..18500)
                     /gene="ugpC"
                     /locus_tag="IVD26_001381"
     CDS             complement(17391..18500)
                     /gene="ugpC"
                     /locus_tag="IVD26_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAP6079368.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18709..19131
                     /gene="mgsA"
                     /locus_tag="IVD26_001382"
     CDS             18709..19131
                     /gene="mgsA"
                     /locus_tag="IVD26_001382"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAP6079369.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19454..19990
                     /locus_tag="IVD26_001383"
     CDS             19454..19990
                     /locus_tag="IVD26_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAP6079370.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20030..21793)
                     /locus_tag="IVD26_001384"
     CDS             complement(20030..21793)
                     /locus_tag="IVD26_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079371.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21796..23511)
                     /locus_tag="IVD26_001385"
     CDS             complement(21796..23511)
                     /locus_tag="IVD26_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079372.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            24452..>24721
                     /locus_tag="IVD26_001386"
     CDS             24452..>24721
                     /locus_tag="IVD26_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP6079373.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCG"
BASE COUNT         7999 a         4479 c         4988 g         7255 t
ORIGIN      
        1 accgtttatt cagataaggg actgtgacaa gacttttgtc acagtttctt tttgtttatt
       61 cttttttatc tttgtatggc aataatagac aatataacga aaattattta atggcttttg
      121 gaagaccatg gaaaaccttg tacaaagcta ttttttctga aaaattcctt gaaacctcac
      181 gaaaaaatca ttattttatg aaaaagacaa aaaaaagtgt tgatttttta ataattattc
      241 attaaactct taaacaactt cagaaaatat taattattct gaaaattcca ataaaggggt
      301 acgtaaaatg aaaaagaaat ttacatttgg tttggttgcg gtatgcggcc ttgtacttgc
      361 tggatgttat ggcggcagtt cagccacaag cagtagttca gcaaaaagcg gttcagcaga
      421 tggaggaggc gtatttaact tagtcgtgcc tcaagaaatg cctacagctg acttatcagt
      481 tgcaacagat acaatcagtt ttacagcatt gaataacgtt tatgaaggaa tttaccgtct
      541 tgatgaagac agcaaaccac agccggcagg agctagcgag ttggcagaag tcagtgaaga
      601 cggattaact tacaaaatca aattacgaga agacgcaaaa tggtcaaatg gtgatcctgt
      661 tacagcagcg gattacgttt atggctggca acgaacagta gacccagcta cagcttctga
      721 atatgcttac ctgtatgcgc cagttgaaaa tgcagaagac attacagctg gaaagaaaga
      781 taaatcagaa ctagggatca aagcagttgg tgactatgaa ttagaaatca aattgacgaa
      841 acaaacacca tatttccaat atctgcttgc tttcccatca tttttcccac aaaaacaatc
      901 cgtagtggaa gaaaatgggg atgcctatgc atctgcaagt gataaagctg tttataatgg
      961 accattcaca ttagaagatt ttgatggacc aggaacagat acagaatgga cttataagaa
     1021 aaatgatcat tactgggaca aagatacagt aaaactttct gaaatcaaag tcagtgtagt
     1081 aaaagaatct tctactgcat tgaacttatt caaagatggc caagcagatg acgtgatctt
     1141 gtctggtgag ttagcacagc aaaacgcaaa cgatccagct tatacttctg ttaaagaagc
     1201 gcggacaagc tatatcgaat tcaatcaacg tgaaaagaat tcaccattca acaatgtgaa
     1261 cctaagaaaa gctatttctt attctatcga tcgtgaagct ttagtaaaac aagtactagg
     1321 tgacggatca gttgtctcta caggattgat cccatcagat atggtaaaaa gtccaacaac
     1381 gaacgaagac tttgcaaaag aagctggaaa attagtttct tatgacaaag ataaagcaaa
     1441 agaatattgg gaaaaagcga aaaaagaatt gggcgttgat tctttagaat ttgatttgat
     1501 ggcttctgat gatgattcat cgaaaaaagt aatcgaatat gttcaaaact caatccaaga
     1561 aaacttggat ggcgtaacag tcaaaccaac acctgttcca ttctctgtac gtcttgaccg
     1621 ctcaacttcg ggtgattttg acgcagtact aggcggatgg gctgctgact atgcagaccc
     1681 aagcagcttt actgatttgt ttgtcacagg taattcatac aaccgtggtc gctggagcaa
     1741 tgcagaatat gacgaagcag ttaaagcagc ttcatcaaca gacgctggcg atgaacaagc
     1801 ccgttgggat gatttccaaa aagcaatcaa gatcatctct gatgatatgg gtgtcgttcc
     1861 ggtgtaccaa aaagcagaag gtcacctagt gaatgaaaaa atcaaaggta tcgttcacca
     1921 tgcggcaggc gcttcatggg attacaaatg gacatacgtt gaagaataat cgttaatacc
     1981 gtgagcatga gaaaaaacga ggctgcggca aatgtcgcaa cctcgttctc atattcactt
     2041 atcctaacaa agaaaaaagc atgaaaatag cagaaagagc aattagtatt ccggcaatga
     2101 tcagccaaaa gctgtacata ccgtagctgg cagacgagag cgtggaaaat tctggttttt
     2161 tctttcggtt ccttgttcgt gcaagatgga ccgatcgctg aaaatgatcg aagaaacccg
     2221 aagaaaagac ccataaaaaa ccgccgataa tcagaaacgg caatgaccat aagaatagat
     2281 cattagataa ttgaatgagt gtaaaggaat ggttgatgag attttttatt aaaataacca
     2341 gaatcagtag aaaagctact gcgtagggga tagatttttt tttcatttga ttgctccttt
     2401 atttttggtt cattatctaa taatgtagcg aaacatctgt cagaagtcaa aagctagggg
     2461 gaaacattag tgaatagtta tatcaaatat gtattaaaac gtgtcttttt catgatcatc
     2521 acgctttggt taattgcaac aatcaccttt ttcttgatgc aattgctgcc gggcacgcca
     2581 tatacgaatc aggaacgttt gagtcctgaa acaatcgaga tgctaaataa acaagtcggt
     2641 ttggataaac cagttatcgt acaatatggg atttatcttt ctaatttgct tcaaggagat
     2701 tttggaattt ccttccaatt taaaaaccag ccagtcgcac atttgttagc tggaagaatc
     2761 ggaccatcct tgcagttagg gttacaggca attatctttg gaacagtcct agggacgatt
     2821 ttaggaacga tctctgccat gaagcaaaat acatgggcag atacatcttc tacactcgta
     2881 gcgatattag gtcgttccat tccaaacttt gtatttgctg ttttattaca atatatcttt
     2941 gcaatcaaat tacaagtttt gccaatcgca aaatgggatg gctttgtgta cacaatctta
     3001 ccaacaattg cgttggccat gtcgccgctt gctgactctg ctcggtttat ccgtacggaa
     3061 atggtggaag tactgcatag tgattatgtg gaattagcaa aagcaaaagg attgagccgt
     3121 tgggaaatcg cctttaaaca tggtcttcga aatagtttga ttccattgat gactttatta
     3181 ggaccgttag ctgtagcatt gatgaccgga tcactggtgg tagaaaatat ctttgctatt
     3241 cctggtatcg gggaacaatt cgttaagtca atcacaacaa atgattatcc tacgatcatg
     3301 gctgtaacga tcctttactc atttatgctg atttttgtta ttttgatcgt ggatctattg
     3361 tacggtctag ttgatccaag aattcgtgtt tcagaaggga gccgaggata aatggaaatg
     3421 ataccaaagc gttatgaaac agttgcagat atccctgcgg atgaatttct tccattacaa
     3481 aaaaataccg aagaagaacg tgaacagatt actgcacctt ctttgaattt tatccaagat
     3541 tcatggcgcc gtttaaagaa aaacaaagct gccgttattt caatggtttt actattggtc
     3601 atcattttga tctctgtgat cacaatcttt gtttctcctc atgatccaac tgcccaaaac
     3661 gtggcttata tcaatttgcc tcctcgtatt ccgggaatca atatcgatgg attgaatgga
     3721 aaagcaatgg ttggtggtga acttgttgat aaatatgctc aagcaaacgt cccttcaaac
     3781 gtaaatttct ttttaggaac agacggtttg ggacgtgatg tattaagccg cttatttatg
     3841 ggaatgagaa tctcgttgct gatcgcattt attgctgcat tactagatgt aacgattggt
     3901 gtagcttacg ggttggtttc tggtttgtta ggcggacgtg tcgataacgt gatgcaacgt
     3961 tttttggaaa tcttatcagg aattccaaac ctcgttgtca tgattttgat gttggtcgtt
     4021 tttgaaccag gaattttttc aatcgtggct gctatggcca tcacaaactg gataccaatg
     4081 gcacgtatcg ttcgtgcaca aacaatgaaa ttaaaagatc aagaatatgt tttagctgga
     4141 ttgacattag gtgaatcaag aatgaaaatt gcattcaaac atattttgcc gaatatctct
     4201 agtgtcatta ttattcaaat gatgtttagt attccatctg ctattttctt cgaagccttt
     4261 ttaagcttta tcggtttagg tcttacgcct ccgtcagctt cattaggaac gatgttgagc
     4321 gaagggtaca agacattcct gtatctgcct tatctattat ggattccggc agtaacttta
     4381 tcggttatca tgattggctt taacttactt gctgatggat tgcgtgatgc ctttgatcct
     4441 aaaatgaaag agtgaagacg atgacgaaaa ttttagaagt gaaagactta gaaatctctt
     4501 ttgatacgta tgctggaaag gtacgagcga ttcgcggtgt caattttcat ttgaataaag
     4561 gagaaacatt ggcgatcgtt ggggaatctg gaagtggaaa atcagtgacg accagaagca
     4621 tcatgcgctt gctgtcaagc aacgccaata tagatgctgg tcaaatcctc tttaaaggta
     4681 acgatatcgt tggaaaatca gaaagagaga tgcaaaaaat ccgtggtaaa gaaatagcga
     4741 tgattttcca agatccaatg acctctttag atccgacgat gcccattggg aagcaagtcg
     4801 ctgagtccct tagaaagcat aataaagttt caaaaaaaga gggacaaaaa gctgcattag
     4861 aattgcttaa attagttgga atacccgaag ctgagaaacg tatcaacagt tatccgcatc
     4921 agttctcagg aggtcagcgt caacggatcg tgatcgcgat tgcactggta tgttatccgg
     4981 aaatcctgat tgctgatgaa cctacaacag cgcttgatgt gactattcaa gcacagattt
     5041 tggagctgct gaaagaaatt cagacaaaaa tcgatacatc aattatcttt atcactcatg
     5101 accttggtgt agtagcgaat gtcgctgatc gtgtcgctgt catgtatgga ggaagaatcg
     5161 ttgaagttgg aacatcggaa gaaattttct acaacccgca acatccctat acttggggac
     5221 tgcttggttc aatgccgaca ttagatagtg cgaacgatcg attgtatgct attcctggtt
     5281 ctccaccgga tttattgaac ccgccaaaag gagacgcatt ctatccaaga aatgaattcg
     5341 cgatgaaaat cgatgcagaa caagaaccac cattttttga actatcaaaa acacacaagg
     5401 cagcaacttg gctacttgct ccgcaggcac ccaaagtgac accgccagaa gaaatccaac
     5461 gtcgctgggc tatctttaaa gagaaacaaa aacatactta cggtcaagga ggaattgctg
     5521 atgccaaata aactacttga agttaaagga ttgaaacagt atttcaatgt aggaaaaaag
     5581 aatgaagtac atgctgtaaa tgacatcagc tttcacattt atgaaggaga aacattcggt
     5641 ttagttggag aatctggaag cggaaaatcc actactggcc gtacgatcat tcgcttgaat
     5701 gaacctactg atggtgagat attattcgac ggtcaagata taacgaagat caaagataaa
     5761 aaaggtttga cgaaattccg gcatgatgtt cagatgatct ttcaagatcc atacgcttcg
     5821 ttgaatcctc gtatgaaagt cagagatatc attgccgaag gaattgatgt taatggacta
     5881 gctaaatcat ctgaagagcg tgcaaaaaaa gtcgatgatc tattgagaac tgttggattg
     5941 aatccaagcc acggtactcg ttatcctcat gaattttcag gtgggcaacg ccagcgtatt
     6001 ggtattgcac gagcattggc agtaaaaccg cgttttatca tttgtgatga accaatttct
     6061 gcactagatg tgtcgatcca agcccaagtg gtcaatttgt tgcaagatct ccaaaaagaa
     6121 catcaattga cctatctatt tattgcacat gatttgtcga tggttaaaca tattagtgac
     6181 cgaatcggtg taatgcataa cggcttgtta ttagagatgg gaacaagtga tgaaatctat
     6241 aatcacggtg ttcatcctta tacagaaagt ttgttatctg ctattcctct accagatcca
     6301 gaccatgaga gaaaacgcag aagaatcaaa tatcaacctg aaccagatga cggacaagta
     6361 cgtcaacttc gtgaaatcgc accagaacat tttgtctatg caactgagca ggaagtccca
     6421 tattacgcaa aaaaactaaa acgacaaaag gaatctcttc tggttgctaa ctaggaggga
     6481 catagatgct aaaagctttt aaattccgta tgtatccgac agaagaacaa aaacagcaat
     6541 tgattcgtac ttttggatgt gctcgattta cctataacca tttgctgaaa aagcggcaga
     6601 aaagttggca acaaacagga gtagccaatt tttcgctcac acccgctaca ttaaaaaaag
     6661 aatacccatt cttaaaagaa gtagacagtc ttgctttagc aaatgcacag cttaatttgg
     6721 atcgggcttt tcgcaattat ttcaagggac gtgccagctt cccaaagctt aaaacgaaaa
     6781 aaagtatgtg gcaatcttat acgaccaaca accaaacccg tacgatctat ctggaaaatg
     6841 gctacttaaa gttaccaaaa caaaaagaac taatcaagat aaatcagcat cggccagttg
     6901 aaggatcgat tcgctccgct acgatttctg ctcgatataa tgaagaattt tatgtcgcac
     6961 tactttgtga tgtttcgcca gtaaaaaaag aatctttagc taaatggatc gggatcgcct
     7021 atcatccgaa gacattgatc caaacatctc gacctctaga agtaacttta ccaaaatttc
     7081 accagacaga agaaaagctg caacatgcac agcggaaatt gaatgtgaaa gtccgctccg
     7141 ctcaccatag aaagatcagg ttagatcagg caagcaatta tcagaaacaa aagagaaaag
     7201 taatggatct ttatctgaaa caaaagaacc agcgagaaga ttatcttgaa caattatctg
     7261 ggaaattggt caaacaatat gactacttat ttgtagaatc ttttccaaaa gaagaggcac
     7321 atgctgattt ttctattcac gactggcata aattaataac aaaattgcgt tataagtccc
     7381 aatggtataa taaaaaattt cttttgatca ataccgacgg agcagaagaa agcaattccg
     7441 taagaaagag ccaagtagta gaaaaaatgg gcagacattc ggttatcaag ggataaaaaa
     7501 tgaatgaaac tgataggagc gttagggtta gccttgttaa taaaaagtct taatgacttt
     7561 tgtttctagg aatttttctt ttgaagaaaa gctcactaat tatgacaaac caataaaaca
     7621 atagcagaaa aagttcgtac gagctttttc tgctattgtt aattttttat tcagaaagtt
     7681 tacgaataca tcaaaattct gaaacaaaaa acgtaactca caaagagttg tttttgcgtt
     7741 ttttcttgaa tgattaggtc tgaatctttt gctcacaacc ttattcatgg tgccccggct
     7801 tgagctgata gatttttgaa ggacggccga ttcctacagg acgttcaccg atctcatcga
     7861 aatattggag catagctttc ttaaaattgg aatgatcgat cgttttataa tcgatcccta
     7921 agaatttagc aaatactttt cgagcttccg taatcgtgaa atctttacct aaaacttgta
     7981 gaacttgcgg ctcgtgttcc attttattga ctacacggtt gaatgctttc aagatgattt
     8041 gactatggtc aaaagccaaa gtatctttgc cagaagactc tccagtgact aaatcaagcg
     8101 agatagccac ttctccgcta gataaatgga tcttgttact atgacgttct agtgtgaacc
     8161 agcgtacttc cttggcatca tctccggcga ttagcggttc ttctccaata aaggctaagt
     8221 agctgactgt gacgacccag cctcgcggat ctcgattagg cgtactgaat gtatgcagtt
     8281 gctcaatatt ttcttttgaa ataaccacac cagtttcttc ctttgtttct cttaagacgc
     8341 tttctccagt tgactcatcc ttttggacaa agccaccagg caatgcccat gaatttcgat
     8401 aaggatgccc ttttctttgg atcaacaaaa ctttcagctg atcttcttct ttgttatagc
     8461 acatcagtac gatatcgaca gtcaaagagg gcttgtcata ttctggacgt tcctgttttt
     8521 gataccagtt aagaaattct tcttcacttg ctttatgttc ataatataat ttttcttctt
     8581 ctttagaagc aaaacggttc atctgaccac ctccattgac agtaaaagta ctttttacct
     8641 tattgtagca gactctgaaa aaaaaccaag gatttacttg aaaaatctag gttatcattt
     8701 aaatatgaaa aataaatgga agtatgagat tgaataaaaa gaaaagcaga taaaacggca
     8761 atactttata ccgctcttca cgaatggcaa agaagccaca aataacgata tatacgtcaa
     8821 tgataaaacg caaaatccaa gctgctgtca taaaactgtt caaatgccca tggaggttaa
     8881 aataaccata catacgaata taaaaatagc tgaatattaa atgtgctaat gaaagaaaag
     8941 caatactaag tgtaaaaaaa agatgtttct tctgcatgat tgttccagtc ccttactaag
     9001 atagatagtc tttattatac cacgtgtgag gggagaaata aaaagccgtt ttttagtaga
     9061 tatgaaacaa aacaaaaacc cgcatttatt caacctattc atccttttaa aggatagatt
     9121 gaacgtagat agaagtcgtt tatccagtct ttttcatttt gaaaaaaagc taacagcatg
     9181 ctttttttat ggtatactag caaggaaacg aattcgcatc atgcgataaa ggaggaagag
     9241 ccccgtggca gaaaaggaaa ctttttatat cactacgcca atctattatc caagcggcaa
     9301 acttcatatc ggcaactcgt atactacgat tgcatgtgac gcaattgctc gttataaacg
     9361 gttgatgggc tttgatgtgt tttatctcac tggagtggat gaacatggtc aaaaaatcga
     9421 aacaaaagca gaagaactag gtgtaaaacc gcaagaatat gtagataaaa tggcggctga
     9481 tgtcaagaaa ttatggaaaa cgcttgatat cagttatgat aaattcattc gcacgacaga
     9541 tgattaccat aaagcagctg ttcaaaaaat atttgatcgt ttattagaac agggagatat
     9601 ttacttaggt gaatatgaag gctggtactc tgtttctgac gaagaattct ttacagaaac
     9661 acaacttgca gaagtgtaca aagatgacga aggtaacgtg atcggtggta aagcgccaag
     9721 tggacacgaa gtagaattgg taaaagaaga atcatacttc ttccgcatga gcaaatacgc
     9781 agaccgtcta ttggaatact atgaagaaca tcccgaattc atccagccag aatctcgtaa
     9841 aaacgaaatg atcaacaact ttatcaaacc aggattagag gatcttgcag tttcacgaac
     9901 aacttttact tggggagtac cagtcaagag tgatccgaaa catgtggtgt atgtatggat
     9961 cgatgcatta tccaattata ttactgcact aggatatggc tccgaagatg aaagtctatt
    10021 cgaaaaatac tggcctgcag atgttcagat ggtcggtaaa gaaatcgttc gctttcatac
    10081 gatctattgg ccaatcatgc tgatggccct tgatttgcct ctacctaaaa aagtatttgg
    10141 gcatggctgg ctattgatga aagacggaaa aatgtctaaa tcaaaaggaa atgtcgttta
    10201 tcctgaaatg cttgtggaac gttatggttt agatgcactc cgttattatt tgcttcgtgc
    10261 tgttccgttt gggtcagatg gtgtctttac gccagaagat tttgtttccc gtgtcaatta
    10321 tgatctggca aatgatctag ggaacttatt gaatcgaacg attgctatga tcaacaaata
    10381 ttgtgatgga ctcgttcctg actatgcctc acttgtcact ccatttgata gtgaactgtc
    10441 tacgacggct gctaacgttg tcggacgtta ccatgatgca atggaaaaaa tggaattcaa
    10501 tacagcattg gctgaaatct gggtgctgat ttctcgtgca aacaaataca ttgatgaaac
    10561 agaaccatgg gtattagcaa aagacgaaga aaagaaagct gaattgaata gtgtcatgat
    10621 ccatttagct gaatctttgc gtatcgcagc gatattactt cagccaatca tgacagaaac
    10681 gccagagaag atcttcaatc aactaggatt ggactctgaa acaatgaatc ttgaaggatt
    10741 acactttggc gaatttcctt caggaacaaa agtagttgca aaaggtacac caatcttccc
    10801 acgtttagat atggaagaag aagttgcttt tattcaagaa aaaatgtctg aaggtactca
    10861 aacaaacgaa gatacagtca aatgggatcc agaagaaaca gaacttgttt caacgaaaga
    10921 aaaacaaatc aaatttgatg tatttgaaaa agtagaacta aaagtagcag aagtcatcaa
    10981 ctgtcaaaaa gtagaagggg cagataagtt gctgcaattc cgactagatg ctggagacag
    11041 ccaagaccgt caaatcttgt caggaatcgc tgaattttat cctgatccaa gcgaattgat
    11101 cgggaaaaaa gtcgtcattg tagcaaatct gaaaccacga aagatgcgtg gacaaatcag
    11161 tcaaggaatg atcctttctg cagaagcacc agatggctct ttacaagtaa tcgaagcacc
    11221 aaaatccatg ccaaatggct cagaaatcgc atagaaattc aaagggggta tgacactagt
    11281 tgtgtcatac cccctttttc cgaaatttga gaagcaattt tcgtaaattc cttcttatta
    11341 cttgaagcca atcatataat acagaaacag agaactatcc aaaataaatc ctagaaaaag
    11401 aagtacgagc ttcgctgatt tttgttaatt tagaataata ctaataggaa tcgtaaaaac
    11461 agaaaaaaag cataatgata aagggtcggg cagattttaa ttgattcatc tggtactctt
    11521 ttttattgtc cttacattca taaagtttga atgcaatgac tttattacat ctatatttat
    11581 atctaacagt agcgttgatg tgttaattat aagttctatc actttatgtt caattagttt
    11641 gtgctcttat atgtgtgatt gaaaatatag ataaaaaaac aatcatcggc tttgacttcg
    11701 atgattgttt tctttatttt gtaaaaatcc tatcacttga ttttatggta accttttatt
    11761 tttgtcttca aacggcttgg taagagagca gtaagcagtg caaatgggat cgaaaagaca
    11821 taccagaaaa tcgtacgtcc gataccataa tgttgataga gctttgtcaa catcacgtgt
    11881 aacaagatca accctaaaag caaggagcca gctataaacc aatgattatc ccaatgcatg
    11941 acttcactaa gtgccatcac tccaaaagga tagaaataaa aatagatccc gactaaggtc
    12001 atccgccagt tctttgtaaa tgttccgata ttcaataaaa agaaaatcgc tgaaagcaaa
    12061 ataccgatag gcggaaaaag cccaaccaaa aaggaataca acatccccca caagatcatc
    12121 acaggacctt tgatcaatgc aacgattgcg atgaacaaag tcagcaatat tagtttttgt
    12181 gataacgttg caacagtcat taatccaaat aaaattaatg tgaaccaatg ccaatgggac
    12241 tgctgttgtt ctttacggga aaaatcgacc cggttggata aataatctgc taatttcgga
    12301 taagaacgct taaaatccat aaactgttcc tccttcgtgg aaaaggtagg tttagtatac
    12361 gaaaaataaa aaagaaatac atccgtctta agagggagtt tttcactgaa agtggagaaa
    12421 aaagaatggt aaattaaaat attctcagtt atactgaaaa ttataccaaa tttcaaagaa
    12481 gaaagaggat gggaatgaaa ggcaaactaa aacgagaaat caatctgttt ggcgcattag
    12541 ctaccgttat gggaaccgtg atcggtgcag gcgtcttctt caaaactgct gctgttactg
    12601 ctagtactca gtctacaagt ttgacattgc tagcttggct tttgggtggt ttcttaacga
    12661 tctgtgctgg attgacagtg gctgaattag ctacagcaat cccggaaact ggtggagctg
    12721 taaaatatat tgaagctgcg tatggaaaat tgcccagctt tttattagga tgggcgcaaa
    12781 gcttgattta ctttcctgct aatattgctg cattatcgat tatctttgcg acacaattga
    12841 cgaacttatt acaattatct accgattatc ttttgttgat tgcagtgatc accgctgttt
    12901 ctgtgacagg gttgaatttg ttagggacaa aagtcggtgc ttctgtacaa tcagtgacgt
    12961 tgattgttaa attaatacca attgctgtga ttgtcatatg gggattattg accccaggac
    13021 aaggaactgt ccagttattt ccaatcgaag ctggaaaaga tgttactttt gtcgaaggat
    13081 tgagcagtgc gttgttagca acgttgtttg cttatgacgg ctggttaggt gtcggtgcaa
    13141 tggcagggga aatgaaacgg ccggaaaaag atttgcctaa agcaattatt cttggtttga
    13201 gttttgtaac agtcgtttat ctattgatca attttgtttt tttgaaaact ttgccgattg
    13261 atcatcttgc cggtaatttg aatgcagctt ctgaagcatc agacgtcatt tttggaggaa
    13321 tcggtggaaa gctggtcact attgggatct tgatctcggt atacggtgca ttgaacggtt
    13381 atacactaac tgggatccgc gtgccttatg cgatggcttt agaagacgag ctacctttca
    13441 gtaaacagct gacaaagctt tcaaagaagt ttacggttcc ttatgttcct gcggttttcc
    13501 agttagcagt agcttgtatt atgatgagcc ttggttcttt cgacttttta acagacatgt
    13561 tgatttttgt gatgtggcta ttcagtttac tgatttttat cggtgtcttt attttaagaa
    13621 aaaaagcgcc ggaattgcca cgtccatata aagtaccact ttatccaatc gttccgatta
    13681 ttgcgattct cggtgctatt ttcattttag gtatgacgat gatgacgcaa acgaaattag
    13741 cattgatcgg tataggtgtt accttgatag gtatcccagt ctattatcaa aaaaagaaaa
    13801 aacgctcaga agagtaaaat atttcaacaa cagacagaaa aagtacgaac taggtcctct
    13861 agatcttcgt gctttttcta tttcaataaa acaagttctt ctattttgat ttttgctact
    13921 tctgcaagta gtgcttatgt gctaaagtaa gaatgaaaag gagagataaa catgatattt
    13981 gattctcata cccatttaaa tgctgaacag ttcaatgaag atattccaga aacgattcag
    14041 cgagcacaag aaatgggggt aacgaaaatg gcggtcgtgg gcttcgatac gccaacgatt
    14101 gaaaagtctt tgcaattaag ccatgactat ccaaatatat acagtattat cggctggcat
    14161 ccgacagagg ctggcagtta tacgaaagaa atcgaaaata aattacaaga acaattgact
    14221 ttaccaaagg ttgtagcatt aggggaaatt ggcttggatt atcattggat ggaagacccg
    14281 aaagaagtcc aagataaagt atttcgcaga cagattgcta tcgcaaaaga aatgaaccta
    14341 ccaatcagta ttcatactag agaagcactt gaagacacgt atcaaatcct aaaagaagaa
    14401 gatgttcgag atatcggtgg aatcatgcat agtttcagtg gtgattatga atgggcaaaa
    14461 cgatttcttg acttagggat gcatatttca tttagcggtg tcgtcacttt caaaaaagca
    14521 ttagacgtcc aagaggctgc agcaaatgta ccaatcgaac gattacttgt ggaaacagat
    14581 gccccttatc tggcaccagt tccttttaga ggaaagcgaa atgaaccagg ctatactcgt
    14641 tatacagtag aaaagattgc tgaacttcgg aatcttccga cagaagaagt ggctgcccaa
    14701 acatggacaa atgcgcaccg attatttggt ctaagcgaac atggataaga tgaagatcca
    14761 agagattata gtcgttgaag gaaaagacga tacaagaagg ctgcgggaag tagttgatgc
    14821 agatacgata gaaacaatag ggtctgcaat caatgaagag atcctgatgc aaattgaaca
    14881 tgcccaagag actcgtggag tgatcgtttt taccgatcct gatttttcag gagaaaaaat
    14941 aagaaaaatc attatggaag ctgttcctca ggcaaaacat gcttttttgc cgcgcacaca
    15001 agctaaacca aagaaaaagg gaagccttgg tgtcgagcat gcaagtgatg ctgctatttt
    15061 agaagcattg aaaaaggtcg tgacgccaga catttcccaa acggctgttt ctgaaatcac
    15121 tagacaagac cttttagact atggtttaat agctggggca caagcaaaag aaaaacgaga
    15181 aaaactaggt gacgagttgc gcatcggtta cacgaacggc aaacaattgg aaaaacgttt
    15241 gaagatgttt cgtattacgc cgaaagaact cgcccaagca atgaaaatag tggaggaaca
    15301 acatgagtga atatcgtgaa attgcgacac cctctagaac aaaagagatt ttattgaaac
    15361 atggtttttc atttaaaaaa agtttaggac aaaattttct gactgaacca aatattttaa
    15421 ggaaaatcgt agaaactgcg caaatagatg aacatacgaa cgtgatcgaa gttggaccag
    15481 gaatcggtgc attgacggaa caattagcca agcatgcaaa acaagtcgta gcatttgaga
    15541 tcgatgatcg tttgatccct gtattggctg atacgatgca accctatgac aatgtgacta
    15601 ttgtacatca agatatttta aagaccgatt tgtcaacagc tgttagagaa acatttcatg
    15661 aggagcttcc gttaaaagtc gtagcgaatt taccttacta tattacgaca ccgatcatga
    15721 tgcattttct tgaatcagat ttggttgtgg atgaactagt cgtcatgatg caaaaagaag
    15781 tagctgatcg tatctctgct gaaccaggaa cgaaagctta tggttcatta tcgattgctg
    15841 ttcaatatta tatggaagcc agtttagcat tcatcgtacc aaaaacagta tttgtccctc
    15901 agccaaatgt agattcagcg attttgaaac tgacaagaag agatataccg gcagtcgaag
    15961 tgacagacga aaaagcattt ttccgattga caaaagcggc atttcagcaa agaagaaaaa
    16021 cgctttggaa taacttgcag cattcgtatg gcaaagatga ccagacaaaa gcatggttag
    16081 caaaaagctt ggaaacagct ggaatcgatc caaaacgtcg tggggagact ttgtcattac
    16141 aagaattcgc cgcattaagc aatgcgatgt cagaaaatat gcagtaaaaa aagaggttgt
    16201 gacagaagtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa acaaaaatag
    16261 ttcctcatgt ttttcgtttg tttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16321 ttaagaaaga ggttgtgggc ctgccgttta actctaagtc acaaggaaca atttcaaaaa
    16381 acagcttctc atgtttttga gttagttggt cttattactt gatgcaagct tttgaccact
    16441 attatgccga acaaggagat gtgacacaaa ttttgtcaca tctcctattt ttgtttcttg
    16501 atcaaaaaat tcttatactt gatactcaca ctcattttgt atggatttag aaaagaatat
    16561 gtgtcttgac agttattagt aagtgagtta tactaagtcg acatttatgt gtcaagacat
    16621 attaggagag agaaaaaatg agaaaaaatt cagttcgaaa actaacgatt tctgctttat
    16681 tgattgggat gggggtcatt atcccaatgg tcatgcctaa aatcatgatt ccaccagctt
    16741 cctttacttt ggcgtctcat gtgccattat ttattgcgat gttttttaca ccaggagttg
    16801 cagtggctgt tgcgctaggt acgacatttg gtttcttttt aacaacgccg gttatcatcg
    16861 cattgcgagc attgtcacat cttgtgtttg cgttgattgg ggcttggtac ttgcaaaagc
    16921 atccgagtat cgttttaaaa aatggacagt ttacttttgc taattggcgt ttccaagggt
    16981 tcaattttgt gatcggtgtg attcattctt tagcagaaat gctagtagtc agcatctttt
    17041 actttattgg taatatgcct gaaacatatt attctcaagg atatttttat acagtattca
    17101 tcttgatggg gattggtggg cttatccaca gtttagttga ttataatatt gcttatttta
    17161 tagcaggaac actcagcaaa tattttgata tccccgtatt tacggcagca aaaaaagaaa
    17221 atcggaaaga gtcgattcaa gggtacgcga agaaaacgac atattagaca tgatctctca
    17281 aaaaaaaaac tctcatctag taatggataa taaatcctct aagatgagag ttttttgtcc
    17341 taaaaagagc tgcaccaaca tcttctggca cagctctaac agggggcaat ttatggaagt
    17401 ttgatgactt gttctgtttc tttatcaaag aagtggcctt tgctgatgtt gaaggcaagg
    17461 tcgactattt cgcctggttt atggaaatct cttgcatcta cttttgagat gaactcagta
    17521 gaaccagttt ttgtgtaaag catcgtttca gctccaagta attcggaaac gacaacttct
    17581 gatttcacta cggcttcagg tgaagcttca agggctactt gttcactgtg gatgtcttct
    17641 ggacgaatac cgaagataac ttcttttcct tcataacctt tttcaactaa tactttgttt
    17701 tttccttcag gaatacgaag cttaagccca tgtccatctg tgataacacc atttttcaat
    17761 gtcacattaa agaagttcat ggcaggagat ccaataaagc cggcaacgaa catattgacg
    17821 ggtgtatcat aaacttcttt cggtgtaccg atttgttgga taaatccgtc tttcatgata
    17881 acgattcggt cagccatagt cattgcttct gtctgatcgt gagtaacata gatggtcgtt
    17941 gtttcaagac gctggtgaag tttggcaatc tcagcacgca tggctacacg taatttagca
    18001 tctaaatttg ataatggctc atccattaag aagacttttg catcccgaac gattgcccgt
    18061 cccaatgcca cacgttggcg ttgtccacca gataaagcag ctggttttcg tttcaagtat
    18121 tctgtcagac ctaagatctc tgctgcattg tccacacgtt ttttgatgtc tgctttatca
    18181 tatttacgta atttcaagcc aaaagccata ttatcaaaaa cagtcatatg aggatacaat
    18241 gcgtagtttt ggaaaaccat ggcaatatca cggtctttag gtgccacgtc attcatgact
    18301 tttccgccga tatttagttc tccttcagag atatcttcca gtcccgcgat cattcgcaaa
    18361 gtagttgact ttccacaacc ggaaggacca acaaaaacga taaattcacg gtctttgatt
    18421 gatagattaa aatcagttac agaataattt tctgcattgt catatttttt atatacgttt
    18481 ttcagagcca tttctaccat aatacgttcc acactttctt ttttagtttt attaactatt
    18541 taaagtataa atgaaagcgt taactaactt caatgtcatg ttgaacaaga attttttctt
    18601 ttttttgtca atgtgctagt tttaagcttt aataaatatc cataagaaat aaaaactgat
    18661 acactggagt aaataagtat gttaacaata tcaaaaggag tgtctcttat gaaaatcgct
    18721 ttgatcgctc atgaccgaaa aaaacctatg atggtgaaat tagcaacagc gtataaaaca
    18781 atattggaaa aacatgaact ttttgctacc gggacgactg ggcagaggat cacggaagca
    18841 accggcttgc cgatccatcg gtttaaatcc ggaccgttag gcggggatca gcaaattgga
    18901 gccatgattt cggaggatca gttagatttg gtgatttttc ttcgagaccc gctggctgca
    18961 cagccccatg aaccagatgt aacagcactt atccgtttat ctgatgtcta tgagattccg
    19021 ttagctacga atatcggaac agctgaggtg ctactaagag gactggaagc cggcttccta
    19081 gattttcgaa gaatcgtcca tgaaatagac aagcatccac tttcattttg atggataagc
    19141 gtatggaaaa ataacgttta atgttcgcct atatgtagct ataaaagcta aacaaactga
    19201 taatatgcga tataatacga acgtattgga taatataaac aataatatta gtttttcgta
    19261 tttgcagtaa atgtgaaaat atgctatagt ttctgtggga aaagatccca aaaataatac
    19321 agagtagaaa ataaagcgtt aagtgctaag aggatgggat gttgcctctt ggacgaagga
    19381 cgtaatgttc gcggttttat tttcgcattc gctgcatgat acgatgtagc agctcttaaa
    19441 ggagatgcta aaaatgaaga aacaccggtt agacgcacgt atgattgcta ttatgggctt
    19501 attgattgca ttgatggtca ctttgtcccg actggtagca atcgagaccc catttattaa
    19561 aatcagtgtc acatttattc cacaagtgat catgggcatt ctttttggtc ctttttggtc
    19621 agggataggc gcagttttag ctgatttagt aggaatggcc ctcttctcga aatctgcatt
    19681 ctttattgga tttacattga atgcatttat tgaaggagca atctacggat tctttttcta
    19741 tcgaaaagag atcacttgga aaaatgccat tctggctacg cttagtgtca cgctgatcat
    19801 caacttattt ttgacaccat tatggcttgc gttgatgtac catgtgccat tgttcagctg
    19861 ggtcgtttgg gcgccccgcc tgttaaaaac agtaatatgg ttaccgattc aatcaattgc
    19921 catttattac gtaggacgta gtattcctta caaaaaaatt ttaagaagtt tagcgatcca
    19981 cgctaaataa aaaacaagca gtcttcccat cccagaagac tgcttgtttt tattgtgctg
    20041 tgaattgtgc ttgatagagc cgtcggtaat aaccatcttt ttgaagcagc tcatcatggg
    20101 tgcccatttc gacaatagct ccctgatcca tcactaatat ctggtccgca tttttgattg
    20161 tggacaggcg atgggcaatc acaaaactgg tttttccttc catcattgct aagaaggctt
    20221 gttggatttt tttctctgtc aatgtatcga ctgagctggt agcttcatct aagatcaaca
    20281 tagggggatt actgatcatc gttcgagcaa tcgtcaacag ttggcgttgt ccatctgata
    20341 tctttaaccc ttgaccgcca atcttagtat ctaatttttc cggcaaacgt tctacaaatt
    20401 catacatata agaggctttt agggcatcat tgatttctgc gtcacttgct tccggattcc
    20461 caaaacgaag attttctcgc aatgtactgt caaatagcca agtatcttgt aacaccattc
    20521 caaaactttt acgtaatgta tcacgttgga tagagcggat gtcatggtca tcgactgtaa
    20581 ttgttccttt tgttgtgtca taaaaacgca tcagcaaatt aacaagtgtg gattttccgg
    20641 cccctgtttt tcctactata gcaatggttt gacctggata agcagtaaaa ttgaaatctt
    20701 cgatcaaacg ctgcttgggg tcataagaaa aagaaacatg atcaaaagag acttttcctt
    20761 tgatattttt gggttccaag gcataggcat ctggcaaatc aggcttttct tctggctgat
    20821 cgatcaaatc aaatgctcgt tctagaccag aaaaagcggt ttgcagttgt gtcgtgattc
    20881 cagaaagttc gataaatggt ttagaaaact gacttgagta gatcgtaaag ctggaaatca
    20941 caccaacagt gattgacgaa ccactcttca atgccaatag gccgccaact aaaccaatcg
    21001 ataaataagc aaggtgatct acaaaacgag aagacgggtt tgtcaaggaa gaagaaaatt
    21061 gtgcccgttg tcctttttca tatagatcag catttagcag ttcaaattgc tgttgactag
    21121 cttcttcttg ctgaaaagct ttcacgattt tctggttacc gattcgttcg gtcacaaagc
    21181 ccgagatatc cccaataatc ctttgctgtc tatcgaaatt tgtttgtgaa gcacgagcaa
    21241 cgatccaact cacaaggaaa ataattggtg tagaacaaag aacgaccaat gtcagaagtg
    21301 gacttagacg catcataaaa ataaacgaaa gaatgatgat tgccactcca gaaaataatt
    21361 gattgaaggc cgcagaaatt gcaatggaaa tattgtccat atcatttgta aatcgactga
    21421 cgatatttcc gtgggagttt tgatcataat aacgaagtgg caatcgattc agatgagcaa
    21481 atgcatcttt tcttaatttt gcaacggata agtaagctaa ccgattgctt aacacttgga
    21541 tgagccattg actgactacg ttgattaaaa cgataccacc gaatagaata agtaaatgga
    21601 acagtcgatt gaagcggacc tgtccttctc caatcatttg atcgatactt tgaccaattt
    21661 gtaacgtcat cacaactgtt gcaatcccat tgatgattcc tagtatcaca gctagccaaa
    21721 tgtcttttgc ataggcagta aggtaaggaa tgaatcggcg gagcgtctgc aaggataatt
    21781 tttttacttt cataactatt cttcctcctg tgatgcgacg atttcctgat attctgctga
    21841 ttgagcaagt aattcttcat gggtaccctg agcagcaatc ttaccttgat ccatcactaa
    21901 gatatgatgt gcttcttgaa tagagcggac acgttgggag ataataatca ctgtactgcc
    21961 aagataagtc tgtagcgcct tacgcaaatc caagtctgtt tgataatcca acgcacttaa
    22021 agagtcatct aaaatcagta atgctggctt ggcaatcaaa gctcttgcaa tcgtcagtcg
    22081 ctgtttttgt ccgccagaga aatttttccc attttccatg acttttgtat ctaaaccatt
    22141 tggaagctga cggacaaatt cttctgcctg agcgattttc agagcttccc aacattcttt
    22201 ttctgtggcg tctttcttac cccattgaag gttttcacga atagtcccgg taaatagtac
    22261 agaagtttgg ggaacaagag caatttgctg acggagatga tccagctgcc aagaacgaac
    22321 atccattccg tccattataa ctgtaccgga actgacatca tagaaacgcg gaatcaattg
    22381 tgtcaaagtc gttttcccgc ttccggttgg accaatgatt ccaaggactg tatttcgctt
    22441 cagctgaaat gtaatatttt ggagagaaag accagaatca ggagtataac ggaagtcaac
    22501 atggtcaaaa gcgataattg cttcagaaga aaaatcggga gtagtactga cctcagcttc
    22561 aagaatcgaa ttttctgtgt ctagcacctc tttcacccga tttcctgaag cttcggcacg
    22621 tgtgaagatc acgacgaggt ttgaaacaac gatcagtgcc aaaagcattt gattcatata
    22681 attgatcaaa gcaagaactt gtccttgttg caagctacca atatttactt tgatcccgcc
    22741 aactgtcagc aaacagatga tcccgacatt catgatcaag gttgtagcag gtgataatag
    22801 ggcagagata ttggaaacac gtaaataatt gttcgctaga tcatttgtgc ttttatcgaa
    22861 cttctctgtt tctttttttg tctgcgcaaa tgcgcggatg acacgaacac cgctaagatt
    22921 ctgactaacg tgttcattga gctgatctag tttttcttgc actttttggt agagaggaac
    22981 ggtttttttg atgataaaaa ataaaatgat tgagaaaata ggcaataatg ctaagaaaaa
    23041 cagacctact tcccagtcga tcacaaaagc catgaccact gacccgatac ttaaaaacgg
    23101 tgctctgatc aataaacgaa tgaccattgc taaagctagc tgaagctgat tgatgtcgtt
    23161 tgtcattcgg gtgatcaagg tatctgttcc aaaatgattc aactcgttgt gagagaaagt
    23221 attgattttt ttgattagct gattacgtaa ctctgtacca aatccttgtg aagctactga
    23281 agcatagtat tggcaaatga tagcacaaat cagaccaatc acagacatag cgaccatcca
    23341 taagcccatt tcaatgattt ttcctcggtc attcattttt agtccattat cgatcaagga
    23401 agccatcatt aaaggcagga caagttcgaa gacagcttca agaaatttga agaacgggcc
    23461 caaaatgatt tgcttacgat agtcttttgc ataacgtaat aactgaatca tatgattcct
    23521 cctattattt atttgtccac aattgaaaaa acaagtacta ccacattgta gcttaggaaa
    23581 tttagaatga aaagagaaca agccttttca taaatgaaag ttttattatg aagaagcttt
    23641 agaaattgaa tagactattt tttttaaaaa aaagaaaatg agaaaacatg ccagtctctt
    23701 cattcatagg aacgtctatt ttacttaatt tttctataaa tgaattctgc ataaaaaata
    23761 tatcaagtaa atgtttatag atgaaactct atttacttct tttttaattt gttcttgcaa
    23821 tcttttttgc tacgtaattt ttgtaaaaaa gtgggttgag agaaatctaa ttgattttca
    23881 aagaaggagt atgaaaatga gaaaaatatt tattcgttta ttgtgggtac tatcttagag
    23941 gaataaataa tagtggagaa aactatggtt tggcgcagat tctatcaggt ttgatggaac
    24001 gaagacaacc tcccgacatc aagtcaaaag ccacttgaga ttttgatctg aaaataaaaa
    24061 aagaaaacaa ggtaggaaca tcaatgtttc taccttgttt tcgtaatcaa tgggaaaaaa
    24121 ctaagagtgg tgtacgtaat caataaaaag gatggtgaca acagtacctc tttactctct
    24181 gaaagcatca taactcgttt ttcctcatta tgccaataaa ttgttgttat accacatata
    24241 aggatttgta atagctaaaa acagacagga aagttgaaat ctgtgaatct tattttgtat
    24301 ggaaggattt aggttctata atattttgtg ttggtggaaa atcgaaagcg attttctact
    24361 aacacttttt tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac
    24421 caaaacgtca ccctaccaaa ggagtctctc aatggataat catactagaa aattactcgg
    24481 attaacagat aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg
    24541 cgttcaagcg cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg
    24601 tggatcgatt cgtattatcc gcaacggttc ctatacgaca cgcactcaga tgttgaaagt
    24661 caaagaaaag ttgactattt tagaattaaa acgtacccgt tttctctgcc atgattgtgg
    24721 a
//
LOCUS       DACBYO010000035        24385 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.035, whole genome shotgun sequence.
ACCESSION   DACBYO010000035 DACBYO010000000
VERSION     DACBYO010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.035"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="IVD26_001387"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="IVD26_001387"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAP6079374.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="IVD26_001388"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="IVD26_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAP6079375.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVDCREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="IVD26_001389"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="IVD26_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAP6079376.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="IVD26_001390"
     CDS             complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="IVD26_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAP6079377.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="IVD26_001391"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="IVD26_001391"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAP6079378.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="IVD26_001392"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="IVD26_001392"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAP6079379.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="IVD26_001393"
     CDS             complement(8053..8523)
                     /locus_tag="IVD26_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAP6079380.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="IVD26_001394"
     CDS             complement(8569..8994)
                     /locus_tag="IVD26_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAP6079381.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="IVD26_001395"
     CDS             complement(9061..9330)
                     /locus_tag="IVD26_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAP6079382.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="IVD26_001396"
     CDS             complement(9341..10936)
                     /locus_tag="IVD26_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP6079383.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="IVD26_001397"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="IVD26_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAP6079384.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="IVD26_001398"
     CDS             complement(14489..15049)
                     /locus_tag="IVD26_001398"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAP6079385.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="IVD26_001399"
     CDS             15402..16376
                     /locus_tag="IVD26_001399"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAP6079386.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="IVD26_001400"
     CDS             16546..17946
                     /locus_tag="IVD26_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAP6079387.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="IVD26_001401"
     CDS             complement(18024..18746)
                     /locus_tag="IVD26_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP6079388.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="IVD26_001402"
     CDS             complement(18825..19331)
                     /locus_tag="IVD26_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP6079389.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="IVD26_001403"
     CDS             19454..21253
                     /locus_tag="IVD26_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAP6079390.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="IVD26_001404"
     CDS             complement(21321..22895)
                     /locus_tag="IVD26_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079391.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="IVD26_001405"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="IVD26_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAP6079392.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..>24385)
                     /gene="mreC"
                     /locus_tag="IVD26_001406"
     CDS             complement(23663..>24385)
                     /gene="mreC"
                     /locus_tag="IVD26_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAP6079393.1"
                     /translation="NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDS
                     YDDVSQQNKNYEREIEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKD
                     GIEANMAVMSQKGLIGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKN
                     YDEKLHALVVTQLTGDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVY
                     VKPYAEMYDVSVVTIVQRLAED"
BASE COUNT         6728 a         5303 c         4431 g         7923 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaatc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcatt
//
LOCUS       DACBYO010000036        23816 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.036, whole genome shotgun sequence.
ACCESSION   DACBYO010000036 DACBYO010000000
VERSION     DACBYO010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.036"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(54..788)
                     /locus_tag="IVD26_001407"
     CDS             complement(54..788)
                     /locus_tag="IVD26_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAP6079394.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1105..1515
                     /locus_tag="IVD26_001408"
     CDS             1105..1515
                     /locus_tag="IVD26_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAP6079395.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1508..2209
                     /locus_tag="IVD26_001409"
     CDS             1508..2209
                     /locus_tag="IVD26_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAP6079396.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2209..3795
                     /locus_tag="IVD26_001410"
     CDS             2209..3795
                     /locus_tag="IVD26_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP6079397.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3814..4035
                     /locus_tag="IVD26_001411"
     CDS             3814..4035
                     /locus_tag="IVD26_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAP6079398.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4032..4793
                     /locus_tag="IVD26_001412"
     CDS             4032..4793
                     /locus_tag="IVD26_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAP6079399.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5173..5682
                     /locus_tag="IVD26_001413"
     CDS             5173..5682
                     /locus_tag="IVD26_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAP6079400.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5757..6296)
                     /locus_tag="IVD26_001414"
     CDS             complement(5757..6296)
                     /locus_tag="IVD26_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAP6079401.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6436..7047)
                     /gene="rpsD"
                     /locus_tag="IVD26_001415"
     CDS             complement(6436..7047)
                     /gene="rpsD"
                     /locus_tag="IVD26_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAP6079402.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7363..8160
                     /locus_tag="IVD26_001416"
     CDS             7363..8160
                     /locus_tag="IVD26_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAP6079403.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8188..8823
                     /locus_tag="IVD26_001417"
     CDS             8188..8823
                     /locus_tag="IVD26_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAP6079404.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8843..9616
                     /locus_tag="IVD26_001418"
     CDS             8843..9616
                     /locus_tag="IVD26_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6079405.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10024..10821
                     /locus_tag="IVD26_001419"
     CDS             10024..10821
                     /locus_tag="IVD26_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAP6079406.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10799..11212
                     /locus_tag="IVD26_001420"
     CDS             10799..11212
                     /locus_tag="IVD26_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079407.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11196..13841
                     /gene="mutS"
                     /locus_tag="IVD26_001421"
     CDS             11196..13841
                     /gene="mutS"
                     /locus_tag="IVD26_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP6079408.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13859..15967
                     /gene="mutL"
                     /locus_tag="IVD26_001422"
     CDS             13859..15967
                     /gene="mutL"
                     /locus_tag="IVD26_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAP6079409.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15989..16549
                     /locus_tag="IVD26_001423"
     CDS             15989..16549
                     /locus_tag="IVD26_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAP6079410.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16634..18622)
                     /gene="treP"
                     /locus_tag="IVD26_001424"
     CDS             complement(16634..18622)
                     /gene="treP"
                     /locus_tag="IVD26_001424"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAP6079411.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18845..19558
                     /gene="treR"
                     /locus_tag="IVD26_001425"
     CDS             18845..19558
                     /gene="treR"
                     /locus_tag="IVD26_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAP6079412.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19635..20081
                     /gene="msrB"
                     /locus_tag="IVD26_001426"
     CDS             19635..20081
                     /gene="msrB"
                     /locus_tag="IVD26_001426"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAP6079413.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20251..20853
                     /gene="ruvA"
                     /locus_tag="IVD26_001427"
     CDS             20251..20853
                     /gene="ruvA"
                     /locus_tag="IVD26_001427"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAP6079414.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20866..21867
                     /gene="ruvB"
                     /locus_tag="IVD26_001428"
     CDS             20866..21867
                     /gene="ruvB"
                     /locus_tag="IVD26_001428"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAP6079415.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21896..22474
                     /locus_tag="IVD26_001429"
     CDS             21896..22474
                     /locus_tag="IVD26_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAP6079416.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22526..23008
                     /locus_tag="IVD26_001430"
     CDS             22526..23008
                     /locus_tag="IVD26_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAP6079417.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23125..23499
                     /locus_tag="IVD26_001431"
     CDS             23125..23499
                     /locus_tag="IVD26_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079418.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7776 a         4286 c         5113 g         6641 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgtaaa
     1081 gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat tattattttc
     1141 ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc tggaagtatc
     1201 ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc tgaaaaaatc
     1261 ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc tgctggtgta
     1321 ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact gggagcagtc
     1381 gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg tgtagaagct
     1441 ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga aatggaggag
     1501 aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga ctttaggagt
     1561 gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga atcctctcgt
     1621 attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct ataaagacta
     1681 taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg cacttgccat
     1741 ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa tggctgcgat
     1801 tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact tcttctctct
     1861 tcataaagag atggtgatct cattactacc taaatctgta acgacggcta tttctgtcga
     1921 tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg tctctacagg
     1981 tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg aaagtccagt
     2041 tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa aagcaatcga
     2101 gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg gaatattgac
     2161 cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat gcgaaaacca
     2221 ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa agacgtgtat
     2281 ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat tctcctccta
     2341 gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt tgttcagctg
     2401 gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca gcagtttagc
     2461 ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt ttatgatacg
     2521 ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac gctgaaattc
     2581 cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt tgcgcaaaag
     2641 cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca gcaactgcaa
     2701 acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga agaaatcatt
     2761 cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg gccatttgaa
     2821 acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt ttttaatgtt
     2881 cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt ttttttaaga
     2941 aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat ttctgacaat
     3001 ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta ttttcaagta
     3061 gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata ttatagtgat
     3121 cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc gccctttaca
     3181 gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg gctgccagca
     3241 gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt cgcctatctt
     3301 tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa tcatttagtt
     3361 attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag acacaaacat
     3421 cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct gactgtgttt
     3481 aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt aatgacagat
     3541 ttcccattat ttgaagagca actgttagag gagggattac ggacattttt ccgtaatgag
     3601 tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct tctgatttcg
     3661 acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt gactgaagaa
     3721 ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca aaaacaaaaa
     3781 ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat tttaccagaa
     3841 ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact ttatgttgtt
     3901 ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt gatcaaaaca
     3961 agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc agatgattgg
     4021 gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta tttatcacag
     4081 gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa gatgcttttg
     4141 tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga tttcctgaaa
     4201 cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa gcggtatcga
     4261 aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg atattggatg
     4321 cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat gagacgaatg
     4381 tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc caaaaaagcg
     4441 gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt gggatcgctt
     4501 atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg gattacgcag
     4561 gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca atgaatgcgg
     4621 ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca ccagtcaagc
     4681 gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct cctcaagcaa
     4741 gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa taaccttgtg
     4801 tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga tgataaaaaa
     4861 agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat tctttttaat
     4921 aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa cgatattcaa
     4981 aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc tatttttatt
     5041 tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg acacttcagt
     5101 tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta tcttgcaaag
     5161 gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac aacgacagat
     5221 gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt tttgtctgtc
     5281 tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct gtccttgtat
     5341 aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat tgcttctcct
     5401 cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt gcttatcaac
     5461 tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac agcatgcgta
     5521 tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca actacctttt
     5581 ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt cggtgggata
     5641 attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt ttaatttaaa
     5701 atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt ttttgattaa
     5761 tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata agctgctcca
     5821 gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa tgcagttgta
     5881 aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc agcaagagag
     5941 cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc gatcatccaa
     6001 ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg cccaaataaa
     6061 acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc aagtaaaaga
     6121 taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt taatccaata
     6181 gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg agaaaggaca
     6241 gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg gttcataacg
     6301 ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa caaagtgatt
     6361 actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg gtctttttca
     6421 agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag cttcgtcgat
     6481 ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca atttttcagc
     6541 gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt ttactgttac
     6601 gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt ggtatgaagg
     6661 gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt gacgtgcttg
     6721 acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt gttctagtaa
     6781 gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta cgaacaagtt
     6841 acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt cagttaattg
     6901 catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg gtgcgtaagg
     6961 gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac gagaaatttt
     7021 ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata agtttttgga
     7081 gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc ttcacctttg
     7141 cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg agttattatt
     7201 tttctgctgc attattttac acaaattaca gtatatgata gatcatccac gaatgtcaag
     7261 ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat gagagggtat
     7321 gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc ggtatcacca
     7381 ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga aaacagcttt
     7441 tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg aacggctgtg
     7501 gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa gattttatac
     7561 gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga attaggaaca
     7621 tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt aagtaaggca
     7681 gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt atgtggattt
     7741 ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat gttagaatca
     7801 atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat gtttgcgaat
     7861 atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt cggaaaagtg
     7921 atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca cgtgatagcg
     7981 aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga tggaatgaca
     8041 gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat tggtggcggt
     8101 ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta tgtggactaa
     8161 aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa aaatgaggaa
     8221 aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg agtacctaag
     8281 ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt atctatttct
     8341 gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta tcagtatgta
     8401 gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt agtcgtattg
     8461 ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag aaaagtatac
     8521 agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt gtttgaaaaa
     8581 aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta taaacagcaa
     8641 acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa ggaattcttt
     8701 atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc cgattgggta
     8761 aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag taagtattta
     8821 taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata ttgatggaac
     8881 gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg aaaaattacg
     8941 caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg cgcaagagat
     9001 cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg gttttttaga
     9061 ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt tcgttcaaga
     9121 agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca agcgttcttc
     9181 ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg tcttgcctga
     9241 attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat ttttcgatca
     9301 aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct ggcatgagaa
     9361 cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc acttagcaga
     9421 acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa acgaccgtga
     9481 aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag aagtacaagc
     9541 agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg cattgaaaga
     9601 gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta ataagcccag
     9661 ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg cagatgcaag
     9721 ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca agaaataaga
     9781 agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt tctgaagaag
     9841 tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt catagtccca
     9901 tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt ttgtttgacc
     9961 ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga agaggaattt
    10021 agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga gatgattact
    10081 gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt aaatggtgag
    10141 aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt gcaagacggc
    10201 gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt tgagtttgta
    10261 aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc tggacaaggg
    10321 atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca ggctcgttct
    10381 tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga agaagccaga
    10441 aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga aaaacaagca
    10501 atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac acacgttcag
    10561 acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt tgggatgaca
    10621 ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa gtttctgact
    10681 gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag cggctgtatc
    10741 ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca gatcaacgat
    10801 gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc cggaaattca
    10861 aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca ttcgctacaa
    10921 agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag aaaaaatcaa
    10981 acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag cagaaaaaga
    11041 agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc ttgttgtagc
    11101 ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa ctatgataca
    11161 agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact aaaaatactc
    11221 ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt ttgttctatc
    11281 gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca cagcttttgg
    11341 aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg tgcggtgtac
    11401 ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat aaagtagcga
    11461 tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc gaagtgatcc
    11521 agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa gacaacaatt
    11581 ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc gatttaagta
    11641 cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat gaagcctctg
    11701 cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt cgtgaacagc
    11761 taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa aacgcggaat
    11821 ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc ggcaaactat
    11881 tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa gcagtagaat
    11941 accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta gaattaagcc
    12001 aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat gaaacaaaaa
    12061 cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc caggcaaaac
    12121 aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt gaacgtatcg
    12181 atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt cgagtagctt
    12241 tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa caagtgccaa
    12301 tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg ctttcagaaa
    12361 tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat gatccgccgt
    12421 tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc gatatgtacc
    12481 gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa gagcgtcaag
    12541 aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat tatatagaaa
    12601 ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa caaactttag
    12661 caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa atcctcgaag
    12721 cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga gaagaagtca
    12781 aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta gatgtgctac
    12841 aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt gtcagtgaca
    12901 agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta ttaggacatc
    12961 aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg ctgattacag
    13021 gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact gttctgatgg
    13081 cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt gatcggattt
    13141 ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt atggtagaga
    13201 tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt ttgtttgacg
    13261 aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca atcatcgaat
    13321 atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat gaactgacgg
    13381 tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt gaaaaagacg
    13441 gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc tacggcatac
    13501 atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca gatatcctgc
    13561 atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta gaagagaaaa
    13621 ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat caagaccata
    13681 tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa ttatccgaaa
    13741 atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg acgccaatgg
    13801 atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc ggatatcgat
    13861 ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg gagaagtagt
    13921 ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg ccggcagtac
    13981 tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga ttgataacgg
    14041 agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga caagtaagat
    14101 ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg aagctttgcc
    14161 aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag aaaaacaagg
    14221 cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac cactgcgtca
    14281 aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct tgaaatacgt
    14341 gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac tggcattgag
    14401 tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg caactgctgg
    14461 aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg caaaaaaaat
    14521 gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt cattgcctga
    14581 ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt ttatcaagaa
    14641 cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg tcggtcgttt
    14701 ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa atgttcatcc
    14761 gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa ttagtaacgc
    14821 cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata atctacggtt
    14881 taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt tgtcctacgc
    14941 ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgac agacaggtac
    15001 ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata agtctgtgga
    15061 aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag aaaaaacagc
    15121 gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa cagtggaaaa
    15181 atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg aagaacaagc
    15241 agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac tccatcctga
    15301 atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga aattagaaac
    15361 ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc acggaacgta
    15421 tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg cccaagagcg
    15481 cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc tgcaagaatt
    15541 gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa aagagcaaaa
    15601 acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca gctttattgt
    15661 acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc gggagatgat
    15721 cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag caacagcaat
    15781 catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag cacaagcacg
    15841 tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc atggccgtcc
    15901 agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa tccaagaccc
    15961 gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc aatcaccaag
    16021 aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg ctgatatcga
    16081 tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg ctgaagaaaa
    16141 agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg ccagtgacac
    16201 gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg aggctgaatt
    16261 catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg ttttaaaaac
    16321 aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc ctttgacaga
    16381 cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag gggcatacgg
    16441 catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt acagtatcgt
    16501 aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa caaaaaagcg
    16561 gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg aaaagattac
    16621 ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc gggcgaacaa
    16681 gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa gcaacaataa
    16741 tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca atcagggtct
    16801 ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc tttagttcaa
    16861 cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga ataccaatgg
    16921 catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag actttgccgt
    16981 ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact gggtcattta
    17041 cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct tttgttgcaa
    17101 ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt gcgccatttg
    17161 ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc ttattcaaaa
    17221 ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca atgatcattg
    17281 cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc aaaccgccta
    17341 ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct aatccagagc
    17401 cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac atagcaggtt
    17461 cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct tcttttttat
    17521 tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata tttgataaag
    17581 caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata tcgatggcat
    17641 tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg aatacggcac
    17701 taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag atccagcttc
    17761 cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt ggtaacaatg
    17821 aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg aagaagattt
    17881 ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct tgataaccaa
    17941 tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg gctgtggaag
    18001 ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa acgattccta
    18061 atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact ggaagaaaat
    18121 ggaaaattgc ttcaccgggt aaccacaaaa aggcattgac accattccaa aacttcgagt
    18181 gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca tttctgaatc
    18241 caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt tctgctaaaa
    18301 cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt ccttgttctt
    18361 tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta gaaacatcgt
    18421 ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg ctaggtatat
    18481 cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc atacgagtcg
    18541 cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac agcttctcgg
    18601 catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt ctatgcaagt
    18661 tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta ttaaaaagta
    18721 cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa aataggaaca
    18781 ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga gtgagggaaa
    18841 aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt tagcgaaaga
    18901 atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt atggtgtttc
    18961 acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata ttcaaaaaaa
    19021 acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta tttctggatt
    19081 gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga tcatccatac
    19141 gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg agatcggtgc
    19201 gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta tattagacac
    19261 cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac aaggatcgat
    19321 ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa aggagatcac
    19381 agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg acacttatgc
    19441 agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt attctgagtc
    19501 ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa aagtgtaaat
    19561 agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat aggatcacaa
    19621 agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg aaagaaaagt
    19681 tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca tttagcggga
    19741 aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt gaaccgttat
    19801 tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc aaaccaataa
    19861 cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga atagaagttc
    19921 gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca gtagatcaag
    19981 gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat gaaaagatgg
    20041 atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac acaaagagcg
    20101 gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga ttgctatttg
    20161 aaagaaacgc tccctagact ccttttttca caaggtgaaa tgtgctacaa taaagggaac
    20221 gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg tgtggttacc
    20281 tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca gatcgcacta
    20341 ggaaatcctt accgctacag tagcaaacta aatcaaaaaa taaaaattta tgtccatcag
    20401 gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga aaagcaactg
    20461 tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc aatcatggca
    20521 agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac ttatttgacg
    20581 aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct aaaaggaaaa
    20641 ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa cacaaaagac
    20701 gctacagctc tatctgaagc aatggaagct ctctcggctc ttggttacag tgatcgagaa
    20761 atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga tgagtatcta
    20821 cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac agatgaatac
    20881 ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct tcgaccacag
    20941 ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat ttacatcgaa
    21001 gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc tcctggatta
    21061 ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat tcgtacgacg
    21121 agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga actggaagca
    21181 ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga agagatgctt
    21241 tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc aaccgcacat
    21301 ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg ggcaggtatg
    21361 ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata ttatgacgaa
    21421 caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga gatcattgaa
    21481 gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc taatcgcttg
    21541 ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga tcgtcctata
    21601 gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta tgttgaccag
    21661 aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt aagtacgctt
    21721 tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc gtatctgatc
    21781 caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta tgcctatgaa
    21841 cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa aatgaatgag
    21901 tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt gccaaacgca
    21961 atcttttcga aaaatcagcg tccaaaaaat cgcaaacgaa gcaaaaatca atcgacaaac
    22021 attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt gtgaggatgc
    22081 attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc aagcattgaa
    22141 aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc tttctgaccc
    22201 agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca agatttttga
    22261 acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg ctcgtttttt
    22321 ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg aagaaacacc
    22381 gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat attcttatcg
    22441 tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt tggaaaagca
    22501 ataatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt tgggaaatat
    22561 ttgccgttca ccgatggcag aaggcttgct gagaaaacga atagcattag aaggaaggga
    22621 agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa agacaccgca
    22681 ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata tggttgctcg
    22741 gcaaatcaca ccccacgatt ttgaaacttt tgattggatc attggcatgg atcaagaaaa
    22801 tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc atttgttttt
    22861 aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata ccaataactt
    22921 tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata tttggattga
    22981 tgaaaataaa ataacaaaca atttgtaaag ttaacgcttt ctttttaagg cgatgttaga
    23041 gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag taacactttc
    23101 ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat gaagaagctt
    23161 acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa tgacactgaa
    23221 gaacatgcta agaatgtacg attgcaagga aagtttattc ttgagctgca aaaagctgct
    23281 actgaacata gtctagttat cttacaagta agagcaaatc gtttgagtag caagtatgaa
    23341 acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat gatccgccta
    23401 caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa aataacaatc
    23461 ctttcaccag caggggaaca ggaacggtta tcaaaataat ttataccaga tagaaaagca
    23521 cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct ttaagctgat
    23581 atcagtaaaa cggaacgttt taggatgagt atcatagcat gacagcattc ggttgattag
    23641 ttgaatcgat tggatggtac aagttttttt gataaaaaaa ggtcctgcta gccggggagc
    23701 tagcaggata aggagttaaa aatgaaaaag tgttgttagg gttgtttgtt ggtatgctta
    23761 tataatagtc attagttgtg aatattttgt gacgaaagtt ttcgaaagtt gttaag
//
LOCUS       DACBYO010000037        23697 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.037, whole genome shotgun sequence.
ACCESSION   DACBYO010000037 DACBYO010000000
VERSION     DACBYO010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23697
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.037"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(45..1340)
                     /gene="purB"
                     /locus_tag="IVD26_001432"
     CDS             complement(45..1340)
                     /gene="purB"
                     /locus_tag="IVD26_001432"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAP6079419.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1353..2486)
                     /gene="purK"
                     /locus_tag="IVD26_001433"
     CDS             complement(1353..2486)
                     /gene="purK"
                     /locus_tag="IVD26_001433"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAP6079420.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2470..2958)
                     /gene="purE"
                     /locus_tag="IVD26_001434"
     CDS             complement(2470..2958)
                     /gene="purE"
                     /locus_tag="IVD26_001434"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAP6079421.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3374..4681)
                     /locus_tag="IVD26_001435"
     CDS             complement(3374..4681)
                     /locus_tag="IVD26_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAP6079422.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4684..5265)
                     /locus_tag="IVD26_001436"
     CDS             complement(4684..5265)
                     /locus_tag="IVD26_001436"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAP6079423.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5381..5478)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5837..7129)
                     /locus_tag="IVD26_001437"
     CDS             complement(5837..7129)
                     /locus_tag="IVD26_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6079424.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7126..7749)
                     /locus_tag="IVD26_001438"
     CDS             complement(7126..7749)
                     /locus_tag="IVD26_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079425.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7752..8588)
                     /locus_tag="IVD26_001439"
     CDS             complement(7752..8588)
                     /locus_tag="IVD26_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6079426.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8605..9492)
                     /locus_tag="IVD26_001440"
     CDS             complement(8605..9492)
                     /locus_tag="IVD26_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6079427.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9508..10791)
                     /locus_tag="IVD26_001441"
     CDS             complement(9508..10791)
                     /locus_tag="IVD26_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6079428.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11474..12157)
                     /locus_tag="IVD26_001442"
     CDS             complement(11474..12157)
                     /locus_tag="IVD26_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP6079429.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12175..12792)
                     /locus_tag="IVD26_001443"
     CDS             complement(12175..12792)
                     /locus_tag="IVD26_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAP6079430.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12802..13626)
                     /locus_tag="IVD26_001444"
     CDS             complement(12802..13626)
                     /locus_tag="IVD26_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAP6079431.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13619..14179)
                     /locus_tag="IVD26_001445"
     CDS             complement(13619..14179)
                     /locus_tag="IVD26_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079432.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14353..15309
                     /locus_tag="IVD26_001446"
     CDS             14353..15309
                     /locus_tag="IVD26_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6079433.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15614..16570)
                     /locus_tag="IVD26_001447"
     CDS             complement(15614..16570)
                     /locus_tag="IVD26_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAP6079434.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16674..17276
                     /locus_tag="IVD26_001448"
     CDS             16674..17276
                     /locus_tag="IVD26_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP6079435.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17364..18863)
                     /locus_tag="IVD26_001449"
     CDS             complement(17364..18863)
                     /locus_tag="IVD26_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAP6079436.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18879..19403)
                     /locus_tag="IVD26_001450"
     CDS             complement(18879..19403)
                     /locus_tag="IVD26_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079437.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19701..20450
                     /locus_tag="IVD26_001451"
     CDS             19701..20450
                     /locus_tag="IVD26_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAP6079438.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20441..21226
                     /locus_tag="IVD26_001452"
     CDS             20441..21226
                     /locus_tag="IVD26_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP6079439.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21195..21911
                     /locus_tag="IVD26_001453"
     CDS             21195..21911
                     /locus_tag="IVD26_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP6079440.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22013..23032)
                     /locus_tag="IVD26_001454"
     CDS             complement(22013..23032)
                     /locus_tag="IVD26_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAP6079441.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23051..>23697)
                     /locus_tag="IVD26_001455"
     CDS             complement(23051..>23697)
                     /locus_tag="IVD26_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAP6079442.1"
                     /translation="SIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIATFAG
                     LFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLAIGA
                     TLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIVIMM
                     ATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
BASE COUNT         6982 a         5120 c         4146 g         7449 t
ORIGIN      
        1 tttttgctat tctattttaa ttgaattttg caactcactc ttctttattc caaacctact
       61 cgtttgaata tcacgtcaac gtttttcaaa tgatgatgat aatcaaaggc atcgtctatt
      121 tcttctttag ataataccga tgtgatggtt ggatcttctt ctaacagcgg gcggaactgc
      181 acttggttgt cccaagcgta cgcagttttt ggctgaacaa gatcataagc ttcttctctt
      241 gtcattccct tatcgatcaa tttcagcata acgcgctggc tataaatcaa accaaatgtt
      301 gcagacatat tccgcttcat gttttcagga aagaccgtta gatttttaac gatattgcca
      361 aaacgattta acatgtaatt caataaaatc gtggtatcag gcaagatgat tcgttctgct
      421 gaagaatgag aaatatctct ttcatgccat aatgtgacat tttcataggc agtgaccatg
      481 tgtccgcgca ccactctggc tagaccagcc atattttctg aaccgatcgg attccttttg
      541 tgcggcatag cagaagaacc tttttgacct ttcgcaaaaa attcttctac ttcacgtgtt
      601 tcggattttt gcaatccgcg tatctctgtt gcaaaacgtt caatacttgt agcaataagc
      661 gccatcgctg agaaatattc agcatgtaga tcccgaggga gaacttgagt agagatttct
      721 tgtggacgga tccccaattg tttacataca tactcttcaa taaatggcgg gatatttgcg
      781 aacgttccca ctgctcctga gatttttcct gcttctactc cttttgccgc atgttcaaat
      841 cgttcgatgt tccgtttcat ttctgaatac catgtggcaa gtttcaatcc aaaagtagtt
      901 ggttcagcat ggacaccgtg tgtccgaccc atcatcactg tatatttgtg ttcttttgct
      961 ttttcgccaa tgatttccgt aaaacgtttc aagtcttccc gtaaaatatc atttgcttgc
     1021 ttgatgagat agccataagc agtatctacg acatccgtac ttgttagacc ataatggacc
     1081 cattttcttt cttctcccaa tgtttcagaa accgctcgtg taaacgcaac gacatcatgg
     1141 cgtgttaatt tttcgatttc caagatccga tcgatatcaa atgatgcatg ctcacgaatt
     1201 tttttcacat cttcttgcgg gatttcacca agttctgccc aagcttcatc tgctaaaatc
     1261 tcgacttcga gccacgcacg gtatttgttc tcttccgtcc agatattccc catttcaggg
     1321 cgtgtataac gttctaacat gttttttctc ctctaatccc aaatattcgt ttgtttgatt
     1381 tcttccagcg tttgctggat gtcttctgtc aagatagtga tatgtcccat cttgcgacct
     1441 ttttttgctt gtttttttcc atagaaatgg aattgccagt ctggcttatt ctcaatcaag
     1501 cgatagcttt ccagcagttg ttctcccaaa acattgacca ttactgcatt gcttatcaaa
     1561 cgtacttttt ctcctaatgg ccaaccacaa atacctcgaa tatgggcatc gaactgactc
     1621 atagaacaag cttcaataga ataatgtcca gaattgtgag gacgaggagc taattcattc
     1681 acatatagcc cgcctgtttt tgttaaaaac atttctaccc ctaaaacacc tgaaaggctc
     1741 actgcttctg caatcacacg ggcaatacgc tcagcctcct cgatcacatc ctgatcaatc
     1801 gcggctggag caatcgtttc atgaagaata ttgttgtggt ggatgttttc cacgaccgga
     1861 aaagtcgtga aatctccttg accatttcct gccaccatga tcgaaatctc tttttcaaac
     1921 gggatccatg cttctaaaac acaggttcct tctcttaaaa ggtccatggc aggagctaga
     1981 tccgcccgac ttttcaaaac atactgcccc ttgccatcat agccgcctcg agtggttttc
     2041 aaaacacaag gatagccgat cccgtcaatc gcatcttgga tatccgtcgg actgacgatc
     2101 gttgcataag gagcaatcac gatgttattc gtttccaaaa aagatttttc taacaggcgg
     2161 tcttgcgtaa tcgcaagcaa gtctgtccct tgaggaataa atgacatggg taaaatcgca
     2221 tttaacgcct ctacactgac gttttcgaat tcataggtaa tgacatctgt tcttctggca
     2281 agctctttca gcgcaaaggt gtcatcatag acactttcaa tgtgccaatc tgcaacttgt
     2341 gcggctggac aatcgctcac aggatccagc acacctactt taaagcccat ttcttttgca
     2401 ctaatcgcca tcatacgacc taattgaccg ccaccgacga tcccgatcgt tgaaccaggc
     2461 aacaaaggtt taaccaagtt gatcactact ttctataaca gttttagcca acattgaacg
     2521 tctttcagcc aatttagcct ccaattctaa atcatacatg gaaagcatct gtatcgcaag
     2581 tagtccagca ttaattgctc ccgcttttcc gattgctgta gtagctacag gtactcctcc
     2641 aggcatttgg acaatcgaaa gaagcgaatc caaaccattt aatgttcgtg attggaccgg
     2701 tacaccgata accggcaaag ttgtttttga tgcgaccata cccggcagat gcgcggctcc
     2761 ccctgctcct gcaataatga ttttgattcc tttttttcga gcgttttgtg catattcaaa
     2821 catcaaatct ggggttcgat gagcagaaac gacctttttt tcataagaca caccgaattc
     2881 atccaatatt tgacatgctt ctttcattgt ttcccaatct gaagtactcc ccataatcac
     2941 agagattttt gctgtcattg tttttcctcc cagtttttct acattcatat tttaacaatc
     3001 actttttttg atgtcaaaga aatttcgaat gttaacaaag aaaaacattt tattgttcgt
     3061 gtttattaaa gataaaaaaa aggaatgtga caaaagttag gtcacattcc tttttatgga
     3121 taaacggtgt tctcctgcca actcctcggt cacaaggaac aatattcaac aaacatgaga
     3181 agcttttttt tgaaattgtt ccttgtgact cggagatgaa cggcaggctc acgacctctt
     3241 ccttcaacgg tgttcaatca gctgaccctc ggtattagct caaacaaacg gcaaaatacg
     3301 aggaactatt tttccgtttg tttctctaac aatcaggtca aaacgctgat ttcacaacct
     3361 ttcttttgct ctattacttc ttgaaggctt cttccaatat ttcttcatct tttttcaatc
     3421 cattaaagat caaattcaat atgatagccg taatgctact cattacgatg ccatttccag
     3481 tgaacatttg caatgtttgc ggcatttgac tgaataatgt cggcgtaaca ttgaaaccca
     3541 gcccaaatcc aacagaaaca gcaacaatca atagattttt atcattgctg aaatcaactt
     3601 ccaacagcat acggattcct tggactgcca ccatcccgaa catgactaac attcctccac
     3661 caagtaccgg ctcagggatg atttgtgcta acgcaccgat tttagggaat aatcctaaaa
     3721 caatcaagaa gaatgcagag aaatagatgg gttttcttgt tttgattccc gaaagttgaa
     3781 ccaatccgac attttgagaa aagccagtat aagggaatgt attgaaaata ccgcctaaga
     3841 taacggcaag tccttctgca cgatatccct ttttcaattc ttcttctcca acatttttcc
     3901 cagtaatgtc accaagtgca aaatatacac ctgttgattc taccatgctg accatggaaa
     3961 tgatgatcat tagtaaaatc gaccatacgt cgaaagttgg tttaccaaaa taaaagggtt
     4021 gtggaacatg gaacaacggc gcatctccaa tcgcgctcag atcaatcatt cccatgaaag
     4081 cagctaagat gcttcctccg actaaaccaa tcaataccgc gattgaacga atgaaccctt
     4141 ttgccagcat ttgcacgcct acaattagga gaatcgtcac aaatgcaagt agcagatttg
     4201 ttttgtcacc aaaatcagct gctgttgcat tacctccacc cattttctcg attgctacag
     4261 gaatcaaagt caaaccaata acggtgataa ccgttcctgt tactatagga gggaatagtt
     4321 ttttaatttt agaaaagaca ccagaaacta acacaacaaa gatcccagaa gcgataatag
     4381 atccgtagat agctcctact ccttcattgg ttccgatcaa gatcagtgga gctactgctt
     4441 ggatcgcaca tcctaaaacg acaggcaagc caattccgaa aaatcggtta actgtcaatt
     4501 gcaataatgt cgctaatcca cacataaaga tatcaattga aatcaaataa gtcatctgtt
     4561 cttgattaaa gcctagtcct gtaccgatca aaagaggcac cgctactgct cctgcataca
     4621 tcgctagcag atgctgcagc cctaaaaccg cagcttttcc attttgtgtt tctttttcca
     4681 cgattatgcg tcctcctcaa gaaactcaac ttgtccattc gtcaaggaag caatacgcgc
     4741 aagagaaacg actctcaatc ccatttcttc aagtaactga cgtccatctt ggaaagactt
     4801 ttcgatgacg atcccgattc cttctacttg cgctccagct tgctggcata attcgatcaa
     4861 tccttttgcc gcttgtccgt ttgccaagaa atcgtcgata atcaatactt tgtcttctga
     4921 agataaaaat ttacgagaaa tagaaatcgt acttgtcact tgtttcgtaa aagaataaac
     4981 agaagctgtc aataattctt catccatcgt caaacttttt gcttttctag cgaagatcat
     5041 tggaacatct aattctcttg cagcaaataa agctggtgcg atcccagaag cttcaatggt
     5101 cacaactttc gtgattcctt gttctttaaa tacttctgca aaccgttttc ccatttgttc
     5161 catcaataca gggtctactt ggtgagtgac gaagctgtcg acttttaata cgccctcgcc
     5221 taatatacgt ccgtcttttt gaatacgttc aactaattct ttcactttat ttgctccttt
     5281 atcatttatt aataccgaaa taaccgcttt tgtgcaaaaa cctactatgt ttctgttaaa
     5341 gaaaaacacc ctccacttta tcataagaaa agaagggtga aatagccaat cttttactta
     5401 tagtccagca tttacggtac tggctagaaa ctgtcatcca tattatgacg atatataagt
     5461 aggtatgtaa aactaataat agtgtaaatt cattttcttg caactgtttt gcacgtgaag
     5521 gcagtttgcc atatttgaat aaaaaatgtt gtttcaaata ttgaaaacag tctaacacta
     5581 ctttctgaaa ctgacaacgt ggtttactta tttttttgta aaatctaatg atttttaatg
     5641 cattattcct ttttgttcgg gtttaaatag ttatttttat tttctcctat ctaaaaaagc
     5701 agcccacata aaaagaaggc atgacaaaaa gcatgtcata gccccttttt ccgaataaat
     5761 agtgttcaaa agacagccta tcggcaataa ggcaagattt tataaactac gggaagtaat
     5821 ttccgtaaat ctattcttat tcttttaagc tgacaagctc gtcaatcact actgcttttc
     5881 ctgaagcaat agaatgattt gctgcgattc ctgtcaaaat cgacaaaata ccatctacgt
     5941 gagttgctgc ccgattccac ggatcttctt ctttttcttc accaaataga tcatctaata
     6001 aacgcggatc tcctccgcca tgtccgcccg cttcttgttc gacgattacc tcatatggct
     6061 caccgaacat cggatagaca tggatggact gaagaacggc tgctccttca tcctttttat
     6121 ctccacctgc attgatgtaa gacttttcga tcactttcat ttcgatccgt cctttgctgc
     6181 cattgaaaga aacattgaat ccttcccacg gcatatacgc gtttagcgaa tacgtcaaaa
     6241 tcgcaccagt ttcatatttg accgttacgc ctagtgtatc ttcaatagag atatcatcgg
     6301 aaaatacact gcggtcacga atatatccac tgtctttttc tgcttctaaa tacatttctc
     6361 gcaattcctc attggctgac aggtctatag caaatggatc agctttagct agttcgcttc
     6421 catagcatcg actgtaaaat atttctactc cgcgtttctc cgcattatgc atcccataaa
     6481 agtttaatcc accgaatgca aatacctttt ggggacggct gttcaaccaa aaattcacta
     6541 gatcaaaatg atgggtagat ttatgaacaa gaagcccgcc gctattgtgc ttatttcgat
     6601 gccatcttct gaaataatct gccccgtgtt gcgtatttaa cagccattcg aagtggatag
     6661 aaaacacatc accaatcaca tcactttcta tcagttcctt tatcttcgtg tgatacggtg
     6721 cataacgata attaaaagtg actcgcaggc ttcttcccgt ctgtttttgg accgttatta
     6781 tttcttgagc tttttcctca tcgatagtca gaggtttttc gcaaataaca tcatatcctt
     6841 ttttcattgc acgaatgata taatcatgat gcgttcgatc tactgacgta ataatgactt
     6901 cagccggccg tacgtcatcc agtagttgct caaattgtga tggcatacat gtctttactt
     6961 ttttctgtcc atacttgttc acaagtatcc gatttgcata atccatcctt gtttgagata
     7021 catcacaaaa accgactagt tcacaagttt gatgatacgt agaggcaatt gcctcataaa
     7081 aaaaacgcgc tctcccacca agtccgactt gtacatattt tttcttcatt taaagtcatt
     7141 ctccttttct tttaagcaaa atactgtgac aaatggcagc cctggataca gtaatgcagt
     7201 gagtaaaaaa tcatgctgta tacaccagaa cagtccatac aaaaggcata aataccacag
     7261 aaaccccttg acgttttttg acaacagcca gatattcctt ttgatcaaat aaacaagact
     7321 atctgcttta tcttctttgc agatatcaat tagcgtacta aaaaaactat gggatacaaa
     7381 aagcaacaga cacaatagaa aaggaatcag ataccaagct ccaatctttc ccactaataa
     7441 ataccaatca actgcaaaaa taatgacaaa cagctgaaac aacgtaatga tgaaacacat
     7501 ccgtttgatt tttcctttcc tccaacatac ctttttttct gccaagtaat ggacagatag
     7561 ataataagaa ggatacatca tcaaaaaata aatcagatag acaacacgag cagacagcac
     7621 taatcctaaa gtgaacaaac atcctagaac taaagcgaaa agagcattac tgataagact
     7681 ggttaaaaaa atccgacaga catagtagtt gagcttgtaa agaaacatct cttctattgg
     7741 ctttttcata ttcagccctt cagaccgctt gtactgatcc cctggacaag atatttattg
     7801 aagaataaga aaatcagaaa aaccggtagc agcgacaacg tagacatcgc aaacatactc
     7861 gcgtaagtcg tactagatcc agcgtctgca aataatttga tggcaatcga taccgtgtaa
     7921 gatctcggct tgtttaaata aatcaatggt cccatgaagt cgtcccattt ccaataaaac
     7981 tggatgatga tcgtcgtgat gatcgaaggt ttcagcaaag gaaaaataat tttggtaaag
     8041 acactatact tgctgcatcc gtcaataatc gctgattcat ctaactcttt ggggatgctg
     8101 accatgaatt gcatgatctg gtaaatgaaa aatgcttgtc caaaaaaatg tggtaaaatc
     8161 agcggcacat acgtcccaac caaattcagc cgattgtaaa taataaactg cggaatcaaa
     8221 atcacttgtg caggaatcat catcgttact aacatgacga cgaaccagaa tctttttcct
     8281 ttgaaatcga ttctcgataa tgcgtaagca atacaagtcg agctcagaac tgtccctatc
     8341 gtcgaaactg cagagatgac aaacgaattc ctaaagaaag taaaaaatga aattccagca
     8401 aaccccgccc atccttttgc gtaattttcc cattgaaaag tctctggaat caaattcagc
     8461 gaaccactca taatctcttg atccgtttta aaagaacctg cgatcatcca taagaccgga
     8521 taaatcatga ctagacctaa tagcaaaata aaaccgtatt gaaaccattt cgttactgta
     8581 ttattcattt cttcctcctc tcattcacac aacgacccat ttttttgatg atttgaaaat
     8641 cagaaaggtg acagctccca taatcaacag catgatccac gaaatagcac tagcataccc
     8701 catagaatta aaagaaaaag cttggttata cacataaaga gcataaaagt tcgtggcatc
     8761 attcggacca ccttgggtaa tgataaatgc ctgcgtaaaa gtcataaacg ccgcgattgt
     8821 ctgcataacc aagttataca aaatgatcgg cgaaagaaga ggtaacgtga tcttgtaaaa
     8881 cgtctgccat ttgttcgctc catcgatctc tgccgcttca taatacgagc ctgggatctc
     8941 tttgatacct gcagcaaaga tgatcattgc cgaaccgaat tgccaagcag acatcaaaac
     9001 aagagggatc atgaccagtt tttgatcgct aaaccaggaa agcgcaggtg cgcctaatcg
     9061 ttccaggaaa atattcacta acccgttttt agaaaacaac tcccgccaaa ctagagcgat
     9121 agaaatactg ccaccgatca aactaggcac ataatacaaa gaacgaaaga aagtcgttcc
     9181 tttgatattc ctcgttaaaa gataagcaat caatagacca aagatcagtt tcacaggtac
     9241 agatgcaaat acatagagaa aagtgactcg gatggagttc aaaaaacggg catcactcag
     9301 catctttata taattatcca agccgatcca tgagactgga tttcccaaac gataatcggt
     9361 gaacgaataa taaagtgaca agatcatcgg tatcactgtt atcaatagaa atcctaggat
     9421 gaatggagaa gcaaatacgt aaccgaccac attgtcttga tccaagaacc gttttagttt
     9481 ttcttttttc atgccttcct cctgctgcta tcctagaatg tttgacgcaa actcataaag
     9541 actctctgct gcttcttctg ctgttacttc ttcataaatg actttttcaa ctaaaagatt
     9601 gtattggtct tgaatttccg gattcaaagc actatcaaag acattcactt cgccgttgtc
     9661 catatcggaa atcatttcta aataatcaaa tgtcgcttgc aaagttgcat catctgcacg
     9721 agcgagctgt tctcgaatat tcgacatgat tggtacacca cgttctcctt ttaaaatttc
     9781 attggcttct tcactgtttt gaaagaaatc aataaactta gcagcttctt ctttatgggc
     9841 tgagcttttt gccatactca gcatttgcga agaacgtaaa gggataccag attctccatc
     9901 tgcttttctg cgaggtggat taatcaactg aatctccata tcttcaggag cccctgacaa
     9961 tatttctgtc aactggttac ttgatagaaa caccattgcc gcttctctat ccctaaccgc
    10021 ctgaaaagac agatccgtcg tacttgcagc tccaccacct ggttctggat gggccccttt
    10081 gtctaccaga tttttacgca gctggaaaaa atctgttaga tagtctggat tttcaaatcc
    10141 caagctgtta gatagatctt cccgattata aaaattcaat cctttctcaa cttgtggtat
    10201 ttgaataata cagccagcta taaaatcttc gaatcttgaa atagcataga ttcctaattc
    10261 ttcagtgatt tgatagctga tttgttcaaa ttcatcccat gtccaatttg aagctggttc
    10321 agggatattt aattgttcaa atatattttt attgtaagca atcgcaaacg aattcacccc
    10381 gttagacagt ccaactaatt gcccgtcgta agtcgtcgtt gctaaatagg attcatctgc
    10441 attagaaata tcaattatcc cttgctccac atattcatct aatggttcaa tctgattgat
    10501 gtattgagga aattgattgt tcagttggaa aatgtcccag atatcatctg atgctgctag
    10561 tgtacctaat tttgtgtaat atccttcata atcataaaat tcataatcga tcgtcacatg
    10621 gggatttttt tcttcataaa gctcgattac ttttactgtt gcatcgtgtc ggacttgcga
    10681 accccaccaa gccatgttca gcgtgatttt tttgtcatct tcttgcccac aagccgtcaa
    10741 gaagaataac ataacactta aagctaagat gattctcatt cttttcttca ttctctgcac
    10801 ctctacttcc attgttattt ttcaatatac tgtattttta tacagaacat atttattaaa
    10861 cgatcttttt caaggggaat aaaaaccaag acttgcctta tcgttctgcc taggatgaac
    10921 aactcaatac tttcaagaaa aattagatag tgctgattct tctttcatcg ctaaaaacac
    10981 ttcttgcttc aatgatggga ggataattac gcaaagaaaa aaggatatca gacaactgcc
    11041 caatatcctt gacatagcta aataagcatg cttcttcgtg tgcgctcttc cctaaaaaac
    11101 agaaaaataa ctagtaattc tgtatgaaat taggtacaat atacacgtcg atgcacaagc
    11161 attgactatg gcaacttgat tggtcagttc ccgctgactt ttcaagcccc gacaatttag
    11221 ctgctactaa attgtcgggt gcctttttta gtttttattc gtttttcatt ctatagaaag
    11281 cgcttcaata aatcaagaca tttttttgtt agaatgctaa taataacaaa aggttttaac
    11341 tcttcttatg tacattacag gtaaaaaaac aaaaaaattt ctcttttttt tgaattctga
    11401 acaaatagta ctggagtaca aaagacgagg aagagccact atctgctctt cctcgtcttt
    11461 tgattctcac ctgttattca tgattctttt tctcagtttc ccgatatttt tccattttac
    11521 gactaaaaag ctctccgcta cttggtggcg tatatgtgat ggcatttgct cctgcttgaa
    11581 tggtctcagc aatactttct tccgttggac cacctgtcgc aatgatagga agttcaggat
    11641 attttttacg aaaatggcgt actgcttctg cagtttcttt acctgcactg atattgataa
    11701 tcgaaatacc agctgctaac ttttcatcta tttctgtata tttcgacgtt accgtactga
    11761 taactggaat atcaactact cgacaaactt cttttactgt ctctaaaggc gtaggaccgt
    11821 tcaaaacgac ccctaacgaa ccttgcgctt ctgcgaacat gctcatgtag gaagaacgag
    11881 caccttgtgt caaaccacca cctacaccgg agaaaactgg aatgtcagct gcctcaataa
    11941 tgcttttagt aatcgctgga tgaggtgtaa aaggatacac agcaattact gcattcgcat
    12001 ttgtattacg tatgatcgca atatccgtag taaagatgat cgaacggatc aattttccaa
    12061 atatcttgat cccgcttgct tctaaaatga tttccggtac tcttacgata tcttttctca
    12121 attccgtcat gatttctggc gtaaattgtt ctgccatcag ccacttctcc tttgctatct
    12181 ccggtcatac tgattcaatt gatacgtctc gatgacctgg atgatttttt gcgcataacc
    12241 ggggtctgtc gcataacctg catcttgcaa tgcttgtgcg gcttcctgat agttggtggc
    12301 cgtaatcact ttttcataca gcgcaggatt ccaatctact ccttggacga acagttgtgt
    12361 atggtcatcc atggactgtt cccatgaatc atacactttg aagtctcctt ggatagttat
    12421 ccattcttcg ttaacaaatt cctttgtttc caggcttact ttcttctgat ccccataagc
    12481 cttgatcccg aaaagattat tgtatttgct agccaaggta ctttttcccc aatttgattc
    12541 taatatagct tgtcctaaaa tgatactagg aagcactcca taaccatctt gtagttcttg
    12601 ggcatgcgga acaagccgtt caataaattg ctgatgggat tgcgcttcat tttcttgctg
    12661 attatcagta aaaggagaag acagattctt caaggaaaaa acaaaggcta agagtatcac
    12721 tgctacaccg gcaaccactg ctggccaacg gatattcttg cgcttttgct ttttccactt
    12781 ttttttcgcc atgatcaatt cctacttttc atttaattca ttcagatatt cttctagcgt
    12841 caattggtgt ttggtgatat actcagcgtt ttctttaccg acataacgta agtgccaagg
    12901 ttcatatgtg atcttagtta tatcttcgtg tccttttgga taacgaacga taaatccata
    12961 ctgcgcagca ttatctgcga tccatttagc tccaggctga tctccgtaac ttgcatccaa
    13021 tacagtagaa ggataactgt tgtaccagtt ttgatcgacg acatcgactg ccagacctgt
    13081 gtggtgttcg ctgtatcctg gctccgtaat cgtttcttta gtaatctttg tcgcctcctc
    13141 ttctgataca ccttgacgac tcatcacatc ttggacattt tgttcgaaaa cttgttgttg
    13201 ggatgataca gaccggtaag ctgagaccat cactaatgga aatccagctg cttcagcagc
    13261 cttggcaaat gcttcatatt ctggagcaat gcgtttgtcg atcaagtatc cgttacttaa
    13321 tgatgccaat tgagtagact catcaatttc tttttctaat ttgtgatctg gaccaaccaa
    13381 aactagcttc caatcgtctg ttttaacatc tggcaattgt ttggacgtac gatcttttgt
    13441 ttctttgtcc tttaccttgc tgctggttgt ttgactgttc ttttctttac tagcagttgt
    13501 tttggtgctt gttcgttcga ctgcttgatt gccggcttga acatgcgaat catcatcgct
    13561 aaaaataaca tagcccattg ctgcgatcat aatcacaact gctccaaatc ctaaaaattt
    13621 attcacttga aaaatccttt cgttgttctt cacgttcccc attcgcctca tgaacgtaag
    13681 tttcttccag attttcattc acccaatcga gaagttcgat tttttctcct tcgatctgtt
    13741 tttgaacatc tgctggcaga cgaaaattca aaatatcatc atagccccat tcatcatatt
    13801 gaatacttac tttcaagtca aggtatctac cagcctgctg attatttttc aaagggatca
    13861 gctcgacttt tgctgctttg ctgctaagcc atttttgcgc gatgcgtgtt ttgatttgct
    13921 tgtactctgc aacggcaacg tttcgttttt cgggaaaaat aatcgtttga cgcaaaatct
    13981 tttgcgttag catccattca taatcagtga aaagattttt tactttctgc atcgcttcag
    14041 atggcagatt tttctcgcca tctttccatt tttgccattg ttctggactg atcagcaagt
    14101 attcatctaa aaaatttttt tcagtttcaa actgttctaa taatacactc ataataagat
    14161 caatatatac ttgatgcacg tttatcccct ccttttaact attctactta agttttgatc
    14221 aaaaagcacc tcttaaatcg ctgctttcat tttttttaat gtttcaagtc ctctcctctt
    14281 tattcttcgt gatttttgtt ataataatag acagacaaga aactcaatcc aactatgaag
    14341 gagcgttttc agatgaaaaa atatcaatgg ggaatcgttg gtcttggtac catcgcacat
    14401 gagtttgccg aaagcttcaa tcaagagacg agcgaactaa cagcagttgc ttccagaact
    14461 tcagaaaaag cggaaaactt cgctcaccgt tacaatattc caaaagctta cggaagctat
    14521 caagaaatgt tagacgatgc tgaaatcgac atcgtgtaca ttgctgtacc aaatagacag
    14581 catatcgacc atatcttggc agcattggaa gcaggcaaac acgttctatg tgaaaaagcc
    14641 atcacgatga ataaaaaaga actggctgac gctatgcgct tagcagaaga aaagaatttg
    14701 atcttagcag aagcgatgac aatcttcaac atgccacttt atcagcagtt acgctcaata
    14761 atggatacag gaaaactggg ggctttaaaa atgatccaag cacctttcgg cagttacaaa
    14821 gaaccagacc ctaaaaaccg gttcttcaat ccagaattag ctggaggagc tctgttggat
    14881 atcggtacgt atgctgtatc tttcgctcgt ttctttttga gctctcaacc tgaagtagtt
    14941 gcctctacaa tggttccttt tgaaacaggc gtggacgaac aatccgtcac tatcttgcgt
    15001 aacaaagaaa atgaacttgc tgctgtcagc ttgacttttc aggcaaaaat gccaaaagtc
    15061 ggtatcgttg cctttgagaa cggttatgtg acgattgctg attacccgcg tgctgatcgt
    15121 gcggagatct tatttacaga tggtacaaag gaattcatcg aaagcgggaa tacatctgaa
    15181 gcaatgaatt acgaaataaa gaatatggta cacatgattg aaggtgactt gcccaatcgc
    15241 tctctcttct tgacaaaaga tgtcatcgaa atcttggatc aaatgcaagt tctatggaaa
    15301 aatatgtaat tttaaaaggt tgtgaaaaag ctgttctgca tcaagtaata agaacagcca
    15361 aacaaaaata gctcctccta tttttcgttt ggctggactt attaccgcag aggaaagctt
    15421 ttgaacaccg tttaagaaag aggttgtgag cctaccgttc agctccgagt cacaaggagc
    15481 aatttcaaaa aacagcttct catgtttgtt gaatattgtg acttgtgacc gaggagttga
    15541 caggagaaca ccgtttaaag aagaggttgt gaaatcagct ttttgacctg aatattagct
    15601 gaattcacaa cctctatttt tggatttttt gttgggagaa ttctgccttg atttcaataa
    15661 aacttttaaa agactgcaaa aactggaaca attctgctcg atcctcgaat tcagggcgac
    15721 tagtcggcag aggcatttgc cgatacaata cataaacttc ttcaatacgt gttaaaattt
    15781 gtctgccatc atttgactct gaaaatgttt ctgcagtata aatcaataaa ccatagatat
    15841 gttttccata ataagctggt tgctggattc tctctagatt ttccagcatg tctttaatca
    15901 cattggcctg tgctcttctc atagagaagt aagtttcgta gtatagcggc tgtctgagcc
    15961 agtagttttc ttgatgttct ctggcatctt cttggctttc gcgaatgaat gtcagtaaat
    16021 gttcgcattt gatctgcaca tcttctttat tttctgataa aagaaattct gccatttgtc
    16081 tcaaaatatt tcgaaattct ttttcgatct gtatttggtt ttccttcagc tgcttcgtac
    16141 gatctggcat gtaaacattt gcaagcaaag caaatactaa tccaatcgcc attaatcccg
    16201 cttcattgcc gatcagctgc caagacatgt tttcctccac taaataatga gtgaccaaaa
    16261 ccgaatttac tactatccct tcggttaatt tgaagcgaga ggcaagcggg atgaacagga
    16321 ataaaaaaag actgaagcca aaaatagtat acccaacagc aaaaaaactg aacagtgctg
    16381 ttgccgtagc taatataaag gctgcgattc gattcatgcc cgtacgcaat gtagagcgct
    16441 tggtatttcc tacacttaat aatgcaatga tccctgcagc tggccaatac aacagcgata
    16501 agctacccgc tgtgaccatc gaaaagaaga cactgatcac tgttttgact gttcgcattc
    16561 ctatacgcat ttacttcccc cttttttatt ttaattatac ttgaataatg aaaaactagc
    16621 tatcagacaa aagtttaggt atgatagtaa aaagaccaaa aaggagaatc tctatgcaat
    16681 ttggccgttt tcgactaggt atgcgtacga tcaaaagtgc cttagctgtt tttttatgta
    16741 tcttgttttt tcatttgact caacgaggaa tcccgatgat tgctgcatta tctgctgttt
    16801 tttctttgcg tcaggacttg actacaaccg tttcttttgg aaagtctagg atcatcggca
    16861 atacattagg tggtacatta gctatcattt atttttttgt caaaagctat tttcacaatg
    16921 attttttggt agaattgatc ttgcttccta ttctagttat tattgtgatc gtcgtgtcag
    16981 atggtattaa caataattcc ggtatcattt ccgcaatagc tacgttgttg ctgattgcgt
    17041 tgagcatccc tcaaggcgaa tccgctttgt atgctatcca acgtgtacta gatactttta
    17101 tagggacatt cattgcaatc ggtatcaatt tctttcttcg tcctcctgaa acagaaaaga
    17161 aggaagaact atcagaagat ttggtcgaac tccaaaagaa agaacgattg ctaagaacaa
    17221 atttacaaga gatagaagct aagatccaaa aacaaaagaa aaatagcgag gactaatttt
    17281 cttttgcaat aaaataaaaa aatggagaga agaactttaa aaagtcttcc tccatttttg
    17341 attgaacggt gaagtgtact actttattct tccttcatcg agttttgttc tgcctctttt
    17401 ggcgcttcat acatatttac ttggctagta gtcccacgtg tcgacaaatt ctctacgatt
    17461 tccttcaagt caagtcctgt tgtcgctttt agtgtttctt gagtagaaga aagcaaattt
    17521 gtggcataat ttgtcactcg gttcgctcca ctggtttctc ctgaactgct tcctgtatcg
    17581 acaacagaga ttttttcgat atttcctagc ggctgtgctg cttcgcgcat caattgcggt
    17641 agcatatcga taaccatact caagacagct gcttcgccat attccttgaa ggcattggcg
    17701 atcttttgtt ttgcttcggc ttctgctttt ccttttgcta gtgctgcttc ggcttctgct
    17761 tgtccagcta aacgtgtctt attggcttcc gcttctgcca gtgcttccac acggaatcgt
    17821 tctgcttcgg cttcagtcac ttctttgact ttttgagctt gtgcttcttg ttctttagcg
    17881 taccgatcgg catctgcttt tttcttcact tccgaatcat attgcttttc acgacgtgtg
    17941 atttcttttt cttccagttc gatttgtttt tgacgttcta cgattttaat ctgcatttcc
    18001 tgttcgatta cttgttgttg tgctcgggca ctttctaaat tgtaggcttg gtctgctttt
    18061 gctttagcaa catcttgttc ttgtttgtag gttgctaatt tcagttcttt ttcttttaat
    18121 gattctgcga tctctgtttg tcgctgtaat tcagctgctt gtgattcttt ttctgcttga
    18181 gcttttttga tacgcgtttc ttttagagct tccgcttctg ctatatctgc atctcttttg
    18241 acttgggcga ttcttggttt ccctaaagag tcaagataac cgtttttgtc tctgacctct
    18301 ttgatagtga aagaaacgat gatcaacccc atttttgcaa ggtctacaga agcgacttct
    18361 tgtacgcttt gactgaactt atcgcgattt tgatagattt cttctacagt catagaacca
    18421 agaatcgagc gcaagtgtcc ttctaatact tctcttgctt cattttccag ttcttctctt
    18481 gtcttgccta aaaactgttc tgctgctgta gcaatctctt ctacagatga accgattttg
    18541 atgatcgaag taccatcaca catcaccggt acgccttgtt ccgtatacac ttcaggggtg
    18601 gagacgtcca atttactcga taatagactg atccgattcg aacgttgaaa aactggcaag
    18661 acgaatgcgc cacctccacg cacaattttg attttgttat tgctttcatc aatgtgcaca
    18721 tttttgcttc ctaaataact tccactgatg atcaacgctt catccggttt tgctgtctgg
    18781 tacttcgcta caaagacgat cagcaacatc agtaaaatca aagctgcgat tgcgatcgcg
    18841 ataaaaacaa ctggtatttc catttaacac acgctccttt aagcttttat catgctttca
    18901 taaggcatga cataacagat tctttccttg atctcaatga tcaatacttt cgttccccgc
    18961 tcagctgtct gttcttgggg gctgtaaaaa caagctggac gactaatgga accggtaaca
    19021 cttttcaact gaatttctcc catacctcgt acagggatcg gtgtgatcac aacagctact
    19081 tgtccttcca gagttttttc agaagacgac atcgttgatt cggcatgttt catcggcatc
    19141 aatatataga aattaagcaa aaataccaac actatcgata tgcctccact agcaataaat
    19201 aaaaataaag atgattgatc tgttaaacgc tcacctagaa aaccaaataa gcttgtgaaa
    19261 gttaaccaag ggataataag catcggatca agcgggccat caaaatcgaa tacatctcca
    19321 aaaataatca ataggactgc caatcctgca caaatcagca atgtatacca ataaatcgtc
    19381 tcaagtgcga ttccccctat catatacacg cctccttcca tttctacgtc tatcatacca
    19441 atgtttgaaa attctgtata gcttctttta ccgactcagt ggtgtttttt ataggaaggt
    19501 tgtgtttatc gttgacaatt tgttaaattt ttgttttcat gttaaaattt tcacaataaa
    19561 ttctttcgag gtagcctatg tttccttttt ttaagaaaaa accattaaag ctccagaaca
    19621 cgatcatcct tgtcgtttgt ttctccacat tcgtttcttt gattgtttct gccatattga
    19681 tcaggaattt tattctttcg atgaaccgat ctagtgtgtc agataaaatc tctagcattg
    19741 ctaaaatcgt tgccaatgat aaactcatcc aaaaaaagct gcagactggt gacccgacac
    19801 atgcgattca aggaataaca aatgaaatca tgattgcatc gaatttagat tttatcgttg
    19861 tcatggaccc tgaaggcatt cgatattctc acgcagaccc aagttacatc ggtcttcctt
    19921 tctcaagtca tgaagatgtg aaaaaagtga ttggaggaca agaatttttc tctgaaaaag
    19981 aaggaatgtt agggttcggc ttccgctatt tcgtccctat ttattatgat caagagatta
    20041 ttggtgcagt ttgtgttggc ttaacaaaca acacgattga caatcaagtc aaagatggac
    20101 aaaaaatgat tgttttttca ttgattattg gacttagcgt aggcatcata ggcgccgttt
    20161 ttcttgccca aaaaatgaaa aaagtactgc ttggacttga accacaagaa atagcagaac
    20221 agttaagtga aaaaacgatt atcgaaaatg aagtagatga aggaatctta gccatctctt
    20281 ctgataaaac tatcctcttg atcaatacac ctgcaaaaaa cattttctac caaacagagc
    20341 agctattgga tttcgaagta ggaaaaaaat cagtgataat ctatatgacg ttttgtttaa
    20401 agagacgatt gagcatcaaa cgaccgttcg gactcaatcc atgtatttaa atgggataga
    20461 aactatttct agcgttacac ctctttttag caatgaccgt tttttaggag cagtcgcaac
    20521 tttacgaaat cgatcagaag taatgaaatt aatggaggag cttgggggga cgaaacaata
    20581 tataaactcc atgagagctc aaacccatga attcatgaat aaacttcatg tcatttctgg
    20641 tttgattgat ttgaagaagt atgaagaagt cacccatttt atccagcagc taaatcaaaa
    20701 ttataaaaaa gagattggcc aagtctcaag tctgatcaaa gtacctgcaa ttgccggttt
    20761 tttattaggc aaaataaacg aagccaaaga acaatctgtt gaaatgctgt tagaaagcga
    20821 ttcttttatc cctaaaatgg agatggatga ctccatccat tcacttttgc aagtgttagg
    20881 gaacttactt gataatgcaa aagaagccgt gctacaaaaa catgaaagaa acggacaggt
    20941 ccggattcat ttaaactatg acacagaagc tgaagtattc atcgtgaccg tctgcgatga
    21001 cggtgtcggg atatcagaag aaatctcaga aaaaatattt acgctaggtt tttcgacgaa
    21061 gggaatcaat cgtgggtttg gattgaatct catccattca atcgtcaaac gccacggtgg
    21121 atttttagaa ttttccaaac aaacaaatgg cggtacaatc gtctatctag aattaccaaa
    21181 aaaggaagat caaaatgatg acaaatgtcc tgataatcga agatgatcca atggttgcag
    21241 aattgaatcg tacttttgtg gaaagcatcc ctaatatgaa cgtaatcgaa agtttcagaa
    21301 atgtagaaga aggaaaaaaa tatttcagac aaaaaaacgc agatctgctg ctgcttgatg
    21361 tatacatgcc tggcgaaagt ggtatccatt ttttatcttg gcttagacag caaggaaatg
    21421 atatcccagt gattttgatc actgctgcag atgatatcga aaccataaag aatgtgatcc
    21481 gctacggtgc cttagattat ttgatcaaac cgttcacttt gcaacgtttt cagctggcga
    21541 tcgaaaagta tcttgctttc tctcagacaa tccaaacgac tgaaaaagcc gatcagaaat
    21601 tgatcgatca agtattcaac cacaccactc ccattcacga aataccatca ttcatcgatt
    21661 tgcctaaagg tctgtcaaaa ctgactttaa aaaaaataag tgcatttatt ctaaaagaag
    21721 atactatttt ttcaacaaaa gaactggctc aaaaaagctc actgtcacgt atatccgtca
    21781 agaaatattt gaatttttta gtagaacaag atatattgaa cgaaagaatc aaatatttgg
    21841 aaatcggccg gccgctaacc tgttatgaat tgacaaagaa tgggcggaaa aagctcacag
    21901 attactgttg agtcatcgaa ttatcccata caaaatagtc caagtataca gaagtaacaa
    21961 ctgtttactt ggactatttt taaacatttt attgacgaat atccatgttt tcttatctta
    22021 attgacgggc tttaggaaga gatacctcat ttttcgtttt tccagtttct attatttcac
    22081 gaaagttctc gaaacttgtc gaaatcatat ttgataatgc ctcatctgta tttgaaccta
    22141 catgcggggt tacaagaact ctagggtaca tttctactaa ttgctggata gcagggtctg
    22201 gaatcgtctc ccatggcttg aaggatcgga aaaaaacctc tgtttcattt gcaaaaacat
    22261 cggttgcaaa accagctaaa tgattgcttt tcaaagctct taaaatagct tcattatctt
    22321 gaagctctcc acgggctgta ttaatcaaga tgctaccttt tttcatttga gctaaaaatc
    22381 cttcattgat catttgatcg ttttcacctg ggatatgagg tacatgaata ctgacaatat
    22441 cgcttttggc taataactct tcaagcgagt ggaacgtcaa tactttttta gcagcttctg
    22501 tctgatgaat atcgtagccg atcactttgg ctcctagtcc cttaaacaaa acagcttccg
    22561 tcaaccctat cctgcctgtt cctatgatcc ctactgtgca atttctgatt tcacgactaa
    22621 acatttgctc atccactcga aaatctttga aagatgttcg gatcgtcgta tacgcagtat
    22681 ttctcaaaag catcatggca aaagtcaaag ataactctgc tatcgcattt ggcgaatacg
    22741 atggtacacg ggctactgtc ataccaaaat cagctgccgc ttgtagatcg atatgattga
    22801 ctcccacagt ccgtgtaaaa acataacgaa tcccatattc ctgcattttt gcaagattgg
    22861 tctcatctgc tatacaattt cccctcaaca atacagcatc atggtccttt gctgacacga
    22921 tattgtcatg tgtcaacagt tcttcataaa gactgagatc ataatggtaa atattcaatt
    22981 tttcaaaaaa atctatctcg ttcggacgaa caccgtaaca tgcgattctc atactttctt
    23041 cctccatttc ttatgaaaat aaacctatgc catgaatcat ttgtaataca acgatccata
    23101 caggtgtcag taccacagca aaaatagttg acagtaagga tgcattggag gctaaaagtg
    23161 cctccctatc aaaactgata gcataggctg ctgccactgt tgcagctggt gtagccatca
    23221 tgataacgat tgttgccagt gcttcaaaat tgactggtag aatattcgtt gccgtcaaaa
    23281 ctgctagaat cacgatattc aatgcaggta caaataccac tttgactaga ctgtaatacc
    23341 atgaagtttt ttcagatgca gcttttttga agcttacttc acctaatgtt gcgccgattg
    23401 ctagccacgc caatggtgaa cttaaaccag ctaaataatc catcggctga aatagccacg
    23461 gtgcagtctg gtcaattcgc aaaaacgcta cttggcttat ctctccttct gcacctgtaa
    23521 ctgacacttg tggcagatac ccttggaaca gccaaatgaa aaggccggca aaagtagcga
    23581 taatgattgg attgacgaac atcgctttga tatttttagc ttccatcttc aagccactca
    23641 tttttatgta tccataagaa tacaaaaaga ttcggtagcc aatattgaaa attgagg
//
LOCUS       DACBYO010000038        23635 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.038, whole genome shotgun sequence.
ACCESSION   DACBYO010000038 DACBYO010000000
VERSION     DACBYO010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.038"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(60..278)
                     /locus_tag="IVD26_001456"
                     /pseudo
     CDS             complement(60..278)
                     /locus_tag="IVD26_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(544..738)
                     /locus_tag="IVD26_001457"
     CDS             complement(544..738)
                     /locus_tag="IVD26_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079443.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            2090..3130
                     /locus_tag="IVD26_001458"
     CDS             2090..3130
                     /locus_tag="IVD26_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAP6079444.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3954..4286
                     /locus_tag="IVD26_001459"
     CDS             3954..4286
                     /locus_tag="IVD26_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAP6079445.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4905..5246
                     /locus_tag="IVD26_001460"
     CDS             4905..5246
                     /locus_tag="IVD26_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAP6079446.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
     gene            5360..5599
                     /locus_tag="IVD26_001461"
     CDS             5360..5599
                     /locus_tag="IVD26_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079447.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            5666..5875
                     /locus_tag="IVD26_001462"
     CDS             5666..5875
                     /locus_tag="IVD26_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079448.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            5935..6606
                     /locus_tag="IVD26_001463"
     CDS             5935..6606
                     /locus_tag="IVD26_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP6079449.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTCKFIVSEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            6659..8635
                     /locus_tag="IVD26_001464"
     CDS             6659..8635
                     /locus_tag="IVD26_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP6079450.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGANSKYIKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEIVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGIGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGKYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGVLSAVVYFKKKA"
     gene            8650..9402
                     /locus_tag="IVD26_001465"
     CDS             8650..9402
                     /locus_tag="IVD26_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP6079451.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            9418..10179
                     /locus_tag="IVD26_001466"
     CDS             9418..10179
                     /locus_tag="IVD26_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079452.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQT
                     GVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            10192..10452
                     /locus_tag="IVD26_001467"
     CDS             10192..10452
                     /locus_tag="IVD26_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079453.1"
                     /translation="MKLIKLLLFNLSCLTAVFLYCGLLFSQLSILPSYQLYLMRILNI
                     PAVSMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            10449..12539
                     /locus_tag="IVD26_001468"
     CDS             10449..12539
                     /locus_tag="IVD26_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP6079454.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDFGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYTHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDNMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVDYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEVSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            12566..13030
                     /locus_tag="IVD26_001469"
     CDS             12566..13030
                     /locus_tag="IVD26_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079455.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLEIYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRMKEKLIHDGSQSNKYKLQKTSE"
     gene            13027..13269
                     /locus_tag="IVD26_001470"
     CDS             13027..13269
                     /locus_tag="IVD26_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079456.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            13287..13589
                     /locus_tag="IVD26_001471"
     CDS             13287..13589
                     /locus_tag="IVD26_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079457.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            13660..15714
                     /locus_tag="IVD26_001472"
     CDS             13660..15714
                     /locus_tag="IVD26_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079458.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGSLDYQISEGFYPTLIDLIR
                     LDIFKDTDETMSVEESYRNEKILQVLEEELESDQRKVNQVSEVEANEEVPWERPIFPK
                     DESKEKEKGIIDEQADILTHKSIFEEENEVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEDPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLRISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQAQIPKWKKEYEIHQQELKEQEEKQRKKEKEREQLELKKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLTHPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            15714..18326
                     /locus_tag="IVD26_001473"
     CDS             15714..18326
                     /locus_tag="IVD26_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP6079459.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFSEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNEEISEMI
                     GKRLLLESEKVVKE"
     gene            18323..20854
                     /locus_tag="IVD26_001474"
     CDS             18323..20854
                     /locus_tag="IVD26_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079460.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYISSPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEDKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKDND
                     QSFVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            20904..21236
                     /locus_tag="IVD26_001475"
     CDS             20904..21236
                     /locus_tag="IVD26_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079461.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            21237..21830
                     /locus_tag="IVD26_001476"
     CDS             21237..21830
                     /locus_tag="IVD26_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079462.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            21993..>23635
                     /locus_tag="IVD26_001477"
     CDS             21993..>23635
                     /locus_tag="IVD26_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP6079463.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDEC"
BASE COUNT         8710 a         3603 c         4645 g         6677 t
ORIGIN      
        1 ggtattttta ttatatatag atttaacata tgtcggtcgg ttgattgata tagctaaagt
       61 tataactcaa ccgaagccga ttcatctaca cgaataaagt tgcgagtgtt ctcggctaat
      121 tcataaaaat tgttatgtgt tccatatagc aatactggaa taactttatt ttcttgaatc
      181 tcataagcaa ctctatacac ggtgaccgca tacttaaatc cattagacca attacctgat
      241 aaacctccag ttttttgctc ttacttaaat ggatcaatgg caatttcatc acaaacctat
      301 agaggatgag tgacttctgc ctaattacgt taaaaaatat tgaaagtaac tctatgtagc
      361 aaaaaatatc tagaatttca tttcctcaaa actgatcgat attgtatcta aaaatatata
      421 ctacctaaaa taggtagtat atattaaaat atgtgctttt gttagaaaaa tcaatacata
      481 aattatcata tctgtatatg tcatttaggt atttcagtta tgttataata gttttgctgt
      541 ctgctacccc ggcctaatct ggcaagggga ggaggagata taatgaaata cctttttgat
      601 tttgtttttg caatcaagcc acttgcagat gtagtgtgca gttacctctg caaatggctt
      661 gattgcaaaa ttgccaaaaa agacagtaag cctacccgtt aattctataa tatagaaacg
      721 taaaaaaaac cccatcagcc tgcacgctga tggggtttgg tgatataatg aaatacctct
      781 ttgttactca taattatacc ataattagtc acgaatgcaa ccaatagaaa aaactactta
      841 gaacggtaga tcatcgctaa taacaatgca ttgtccacca aatggatttt gtgaagcatt
      901 aaatacattg ttattaattg tcgctgcttt taactaggcc tctccccttc tattataaaa
      961 gaagatatat atcatttctt aattacctac taccttaaac caaaatttaa gtactaccta
     1021 atttaagtag tacttaaaca atctaaaaaa tagttatccc aattgttatg cttttataat
     1081 acgattattt gtaacaaaat gaatattata taattaaaca ctaccatatt taggtagtgt
     1141 ttaattatta gcaaaacaaa aaatatttat tctattctct taacttcaac taagttatgc
     1201 tgcacacctt tatataaatc atatgcaact cattagctag acaaactaca agcatgtagt
     1261 tttatctgtt aattatgtac tacctaaata aagtagttta taattagcaa gtatatatat
     1321 ttaaaaattt aagattaatt tttttatgac ttgtacaaat ttatctgata ttctcttatt
     1381 aagaactacc taatttgggt agttcttatt ttttacattt taagtagtat ttaattgcaa
     1441 tttggtagta tttttttatt atcttattct tagaacggta gtacttaata taaatatagg
     1501 tagtatctaa tttaagtatt aatggtagta tctaaattaa caggtagtat gtaactactt
     1561 taaagtaatt tttttcagat taacacagta gtatcttatt aaataagtta attttaatgg
     1621 tagtacataa ttattatata tatctgacat tggtagtact tattgtattt tttagtagta
     1681 tataatctat tgttttctag cctaaagcct tgtcttataa gaataatata atatatacta
     1741 ctgaaataag gtagtatata ttactagtaa tggtagtatg ttttatatgc ataaggtagt
     1801 tcttaattta ttttttgttt tgacactggt agtacttaat tatctttaat tttaaaacta
     1861 aattttattc atacgttttt ctggtagtat ttaattataa ataatattta tttaaagtag
     1921 ttcttaatga ctttaaaggt agtacataat tcattttatt tctgatttta ggtagtattt
     1981 aattaaaaaa cagttttaat gcgtttgcat tttttattta tctttgctat tttcgaaaag
     2041 agtaggtaat tttacataaa taaaacaacg tgaaagtaga ggatctacaa tgactgattt
     2101 taaatttttt aaggcggata gagtttacaa cgaattattt tatcaatttc caaaagtctt
     2161 tattgtttct gacgaataca aaaaaatgaa agattcaact aagattgcct atatgctttt
     2221 aaaagcaaga ttagagatcg caatcagcaa acggcaaatc gatgaagaag gtaatgttta
     2281 ttttacttat acgacaaatg aactatgtag agtattaaac tgccaaaaac aaaaagcgat
     2341 agcaatcaaa aaagagttgg aatcctttgg tttattatta caaaagcaga tgggatttaa
     2401 caaacagtta gggaaaaata atcctaatag actatatcta gcagaattaa aagtctcaga
     2461 aaatgatatc tacttactcg aaaaatttga tagagagaat agggaaaacg ttgataaatc
     2521 agagggtatg aaaatcatac ccaccctcga cgaaaaatca gacgctgaat cccttggggc
     2581 tcaagagggt atgaaaatca taccgtgcca aaacgttgat aaatcagagg gtatgaaaat
     2641 cataccagaa cttaataata atatattaga cactaataga cacaatatag acactgaaaa
     2701 agaccgccta caagatcaat tgttgttaga caattttgag acaattatga caaacgacag
     2761 cattgctacg tttgtccctg aacgagtatt aaatttgata aaaacatttt cttcaagtta
     2821 cagtgaagct caaaaaaccg tccagactat tcataatgca aagaaaaaag ctgaaataga
     2881 aagtgatatt tcgatagttt ttgaagaact cgatagttat tatgtcaatg cagaacaaga
     2941 attatacacg acactgttaa aagcctatca aaaattaaaa accgaaaaag tcgaaaatat
     3001 ccagaacctg atttttgtct atgtaaaaaa ttggtttatc gaaaaaccaa tagctgctaa
     3061 agtatcaagt gaaaaacgtt tgaattatgc aagctcccca agcactatta cgaaagactg
     3121 gttagagtga aactttactg acaaagtgat tgttgcttca tggagtaaca ttaaaattaa
     3181 aaatttttta ttattctaat tatattacga atattacaaa ataatagcta ttttaataga
     3241 atttataagt taaaatatta tgataaaaat cacaaacgta gccttttacg tcataagtgt
     3301 taaaagaaat aattaatttc aaatatagaa aagggaacgt atgtttgcat actccttttt
     3361 tttgagttat aataatacgc gaagagagat aatttcatta tttaaacaag ctaaaaatct
     3421 tgatattact tcttttcagg caatacgaat attattcgct tacatttttt gtataaattt
     3481 aattgtctgc tatgcttgtg atgaattgat tttcgttttg cacttttgga tgataaattt
     3541 ggacaattga aaatacaaaa aaaagaaagg cggtatgaac tcggaaggct ggtaaccttc
     3601 gtcagcgttc atacacggca ttaagatttg gcccttaatg cgttaacctt tcagtgttac
     3661 ggtattaccc gcaatggatt tagtataaca gatattcaaa agtgatacca ctttttttgg
     3721 ctgtgttaag gttaaaaata cgtgatatta cgatgaatct atgcctaagc ataatgttat
     3781 aaaaatgtcc gtgtggctct ttgccgtatg acgaacgctg aaattagagg gaacgcatgt
     3841 ttggatgcgt tccctctttt ttgtttgtca tgaacgaaaa tcaattctct atttttgaaa
     3901 aataacaaga aaaacttgtt aaaaatattt aaagaaattg ggtggtttat tttatgtcat
     3961 atacaggaat tttgagtctc aaagatattt gtcactacgg taaacggtgt accgctacag
     4021 agaaaatcac gaagaaacta tcaactggcc aaagtaaaac cgttgtgcag tgtaagaaat
     4081 atataatcca gaaagacaaa gtctcagagg aaatgattta ttacattggg aaacaaaagc
     4141 aaataatttt aaaagatcct atccccttaa aagagctata tccaacaatc aaacatgttt
     4201 atgaccaaaa cggtgtactg attggtcgaa gaaaaaatgg agtcttgcgt tgtaccgcaa
     4261 aagggatggg gcgtttgatc ggctgaattg atcattctca taacttgtat tttatcgttt
     4321 ttcgcttgct tgaaaatatt gtcgagactt ctaaaggaac ttagagtcac tagaaaaata
     4381 aggagtagac ttgatctatc aacaattccc ttcggggagt gacggggtag gttttaacga
     4441 ttggtaacgt aaaaaattgg tcaatcgagt aaatgcgctt gtttggatag tggtgaaatg
     4501 aatttgtgta aataataagc gcagagtaaa caagagggaa tttagaagtt agacaagtta
     4561 gaatagcgtc tagattaatc atgagcagct actaagggat ctagactttg acgcaaactc
     4621 atggaataag gagtaggtct tctcgtaatg gggaggacgc acaagaaatt gtgtcgtgtg
     4681 ctgcagtaca tgtagatact tgcgaggacg ttgattattg gatcaatcga gcatttaccg
     4741 ctgtctacta gggtttctcg tttcggacgc cataaacgag tcgaaatttt ttatgtattt
     4801 ttaagtaaac gaaaaacgat aaaatatgaa caagtcctga ataaagtgaa aaaattaata
     4861 taaagcatag agaaaatgaa atttacgtaa tggaggaatg acaaatgaaa aattatgatc
     4921 cgaatatacg attgggcaca catactatta aggtttcttt ccaacgttgg gattacaaag
     4981 gatttgtgac gtttagaagg ggcggaaatt gtaaaggatt agatgtttta gcattagacg
     5041 aggatgattt atacgatcaa acattgactg ataatccaat tggattcggc ttgctacctg
     5101 aagatgatga aggtaatgaa tggtttaaaa tgacgcttat gaatgataat ggagacgaat
     5161 tatctgttga agatacttgg tcatatttga gtgattatat tgtcagcttt gaaatcattg
     5221 aatttgtagc ggataaagaa gaataaaaac tggaggaata aattttacag ataaaggctt
     5281 agaaggagtc acgacgatta ataaaaaggt agtattacct taggcattga gtaaggaatt
     5341 tatttaggag gaatagtaga tggcgcgacc agttttagag gcgatggata tggatacttt
     5401 gacaaaagga aggtatgtac agctgttagc tcgtggttat tcacctaaag aagtattcaa
     5461 agccttatct aaaggaacag atatggaaaa agaaagattg cgaaaagaat tcgattattg
     5521 gagaacccat aatggaatca aggatttgaa accagcacgg ccagtaatta aacgaaagaa
     5581 aaagataacc caagactgaa gtgtagagcg tatgtgatca taggcttttt tatttttgca
     5641 aaaaacaagg aaggtaggaa aactcatgaa ttatgaagaa atcgaaaaca gaaaaaaagt
     5701 gtcgaaagaa atggaagaaa agttactaaa aacgatgaag caaaaacacc ttaaaagatt
     5761 atctgtcgcg caatatatca atgatatgca gttaacagga aaagagaaag cttgtttgtt
     5821 aggttcaatg aaaaactttg aacagttgag acgaacttat agaattcatt tttaaaactt
     5881 tttctatgga aatgagaaaa agtttttttg ttttgtccga aaggaggcag atggatgaaa
     5941 aaatggttat ttggtttttt aggagtcact ttaatcgtct tttgcagtgt gtttggctat
     6001 gttagctacc aaaaacatga aggagaggtg tttaagcaaa atatagaaaa aaagatgccc
     6061 gtagatcaaa tcaatgcaca tgcaaagagt tataaggagg atgcaacgaa cgtcaataat
     6121 gatatgtctt tggggcaaat gttgtccata caaaaagaag caatcgaaat gggcgtcaat
     6181 aaacaagtat ttgcacaaat tcagattcct gcacttggtt tagcattgcc aatttttaaa
     6241 ggggcaaatc aatacacttt gagtcttgga gcggctactt atttttatga agatgccgaa
     6301 atgggcaaag gaaactatgt cctagcaggt cataacatgg aaatgccagg tgttttattt
     6361 tcagatattc aaaagttgtc attaggggag gtgatggact tagttagtaa cgatggcgtc
     6421 tatcgttaca aggtaacgtg taaatttatc gtatctgagt actttaaatt aattgatggc
     6481 gttcctgaag agaactcttt cttgtcttta ccaaagaaag gagagaaacc cttattaacg
     6541 ttgtttactt gtgtttatac gtcacaagga aaagaaagat acgtggtaca gggagagcta
     6601 caataacaag gttgtaatca acgcgagtcg ttgaaatatg aaatgaggag agtaaaaaat
     6661 ggcaataaat cggtatgtaa aaaaagctgg aatgcttgtt ggaatgttag gaatcattgc
     6721 aggctgcttt cagggatatc gagcatatgc agaagatgtc acgcaaaaaa cgccaccaga
     6781 gaaggtcaat atcacggttc ataaattaat gtacgatcaa ggaacgcaat tgaatgttga
     6841 tattgacggg atcaaaaacg atggttatac gcacgatcaa tatcctacag gtgtaacgaa
     6901 atacaacaag gcagattatg gtgatgttga gtttacgtta ggaaatatta cggatcaagt
     6961 attaccgact gaagattctg atctaaccaa cgcgaaggtg gacgaaatcg ttaaagatgt
     7021 agaagacaaa ggtgctaata gcaaatacat taaaaatgca accaacaaaa ttacttcagc
     7081 tgtagatgaa aatggtgaga tcacttttgc ggatcaacca gcctatgtca attccaaagg
     7141 gaatgtatat gtggtttatg aaagtaaatc cgctgctgga ttagtcacac aaaaagcaaa
     7201 accaatggtt gtgattgcgc caatgacaga caatacagga tcaggatttt taaaagatat
     7261 tcatttgtat ccaaagaaca ttgtttctaa gttgagtttt gaattaacga aatttggtga
     7321 cgatggcaca gctcaaagca aacaaacacc tttaaaaggg gcaaaatttg agttatacaa
     7381 gggcgaacct ggaaaaggaa caaaattagg agatcttgta tcggatgatc aaggaaagct
     7441 gactgcgact gatttgacgt taggaaaata ctattttgtg gaagttcctt cagaaattgt
     7501 agtgggatca gataaagaac caacagccga tcaatattta ttaggcgcag acgctcgcaa
     7561 cgatgcgcac aataaattaa cctttgaaat tacgaatgac ggtgtgacaa gcgatttaaa
     7621 agcttcatac gtaaactata aagcaccagt gatcgataaa acagtaacaa atggaacagg
     7681 acaagaacat tctttccaaa ttggtgacgc agtaaattat caaggaacga ttcatatccc
     7741 aacagacatt gcaggcggag cagacggtat cacagtaaac ggcgtgaaaa gcgaaacttc
     7801 tccttacagt gtatttaagt ggggggatac agcaggacaa ggactttctt atgtcgctgc
     7861 taaagcaaat atcaaagtaa caaataaaga tggatctgtg gtattaaaag aaaatacaga
     7921 ttataaaatc caaaattcag aaaatggctt tgtgatcgat tttatcgtga ataatggcca
     7981 agtaagtgat actgtagcaa gtttacacgg acaagatctt caaatgactt ataacatgta
     8041 tgtaaatgat agcgcagctg ttgccaatcc attaacaaat agcgtggatt tcgtttataa
     8101 caacaatcca tttaatcagg aagaacacca cgaaaaaacg aaagctgacg ttgtgactta
     8161 tggtgcaaaa ttcttaaaag tcgatagcgg actatttgga ataggaatca aagcaacacc
     8221 gcttgaaggc gcagaatttg ctgctaaaaa cgcagaagga aaatattatg gtggattagt
     8281 tgatacggat aaagacggtg tcaaagaagc agtatgggta gacgatgtag caaatgcagc
     8341 gatcctaaaa tcagataaag aaggtcactt tgaaatcact ggtttaactg aaggtaaata
     8401 ttcactggaa gaaacaaaag cgcctgaaaa ctatcaaaaa ttaacgaaag agatctcttt
     8461 caaagtagac aaagattcat acaaagaaga aaaccgaatc acgatcaaaa acaatcaaaa
     8521 agcttccgta ccaatgaccg gtagcaacgg ttttcaaacg tatgtattaa tctcttgctt
     8581 gttgctagga gcaggggtac tttctgcagt tgtttacttt aagaagaaag cctagaagga
     8641 tcaaaaccaa tgattatcag gaagcctaag aaaaagcgaa tcatgggtaa atggatcatt
     8701 gctttctggt tactttcagc tgtaggtgtc ttacttttga tgcctgctga agcgagcgtg
     8761 gcgaaatacc aacaaaatca gcagattgcc gcaatcgatc gaacaggaac ggcagcagaa
     8821 acggattctt ctttggatgt tgctaagatt gagttaggcg atcctgttgg tattcttaca
     8881 attccaagta tttctttaaa actaccaatt tatgacggaa cgtccgacaa aattttagaa
     8941 aatggtgtag gtattacgga aggaactggt gatattacag gaggaaacgg taaaaatcct
     9001 ttaatcgcag gtcatagtgg actttataaa gataatcttt ttgatgattt accttcagta
     9061 aaaaagggag aaaagtttta tatcaaagtt gatggtgagc agcacgctta tcaaatcgat
     9121 cggattgagg aagtgcaaaa agacgaacta caaagaaact ttgtcactta cttagaacca
     9181 aatcccaatg aagatcgagt aacgctaatg acatgtacgc ctaaggggat caacacacac
     9241 cgttttctag tgtatgggaa gcgagtaacc tttacaaaat cagaattaaa agatgaagaa
     9301 aataagaaac aaaaattatc ttggaaatgg cttttaggaa gtactgtttt tctttcagtc
     9361 atgatcattg gttcgctatt tgtttataaa aagaaaaaat aaaggagggt aaccaacatg
     9421 agaaatagaa aatggctatt tgtttgtgca gccgctcttt tttctttcac tgcctacaca
     9481 cagttgacgt ttgcagacag acaagaaagc acggatagca cagaacaaac aatccaaacg
     9541 tcagatagca gcacgattca aagcagcgat gaaaccgtcg attcgtcaac agttgattct
     9601 tcagaagaac ctaaaattgc tgaagacgat caaatagtca aacagaccat tcacgttcaa
     9661 aaaattattt cttccgaaca attagacaac caggggcaaa agcttgaaaa acaagaagga
     9721 gtaaatggcg cgaagttttc tgtttatgat gtatcggaca ttttacaaaa gatggatgtt
     9781 aaggatctca ctactgacca aattgaatcc caattaaaag atcgagtgaa aaaactatcc
     9841 agtgatcaac tgaagctaat ttctaatgga gaaacaaaga caattgatca acaaacaggt
     9901 gtctttgaat tctcggtaga agtacaggca aatcagaaac aagcttatta tattgtcaat
     9961 gaatcaagtc ctgaaaacat ttctaatagc gaggatattt tgctattaac acctgtttct
    10021 gataaaaatg gtgaattctt aaaggatgtg tggatttatc ctaaatcaga agcttcgcaa
    10081 cctaaagaag aagtaaaaaa aatcgtatct actggcgtaa agaaaaactt ctttgagaat
    10141 tgttgggatt ttgttactca cttgttttct agagattaag gaagaaataa gatgaaactg
    10201 atcaaattat tattattcaa tctttcttgt ttaaccgcag tctttttgta ctgcggttta
    10261 ttattttctc aactatctat tttgccaagc taccaactat acctaatgag gattttaaac
    10321 ataccagctg tttccatgcc gctagatatt atggaaaagc tcattaggaa tccattattt
    10381 actacgatca atttgatcgt tattgtcgga atttcactag tcatttataa aaaagagggg
    10441 atgaagggat gaattttaaa cactcgtgga caagacggtt aaaatatgtt tttcccataa
    10501 tgatgatgtt aggtacattg tttgggttaa aaacagccaa tgtctttgct gaaaaagtta
    10561 ttgtcgatcc gtcaaatcca atacagaacg taaagaataa ttttattatt ccaaaagatg
    10621 ttcctaatgc aaaaacaaat attactgtaa acggagcgtc aaaagtttac aaatatcatg
    10681 ttgatgccaa caaaggtggt tttacagacg actacgtagg attagtggag ggaaacaaaa
    10741 atatacgcta tccttctttc caaaaggaat acggtgaaac aaaccttgtt ttagaaggcg
    10801 taacaaccaa caccaaagtc aatattgact ttggaaaaat cggtacgtat aacgggaaaa
    10861 aagtcaatat caagctagtt ttatctaata ttcacttata ctcggatacg ttgccgtgga
    10921 atctactaga taataactat acaaaaactc attttcgaga cgatggctat aaaaatacga
    10981 atggtgcaat gagtaaatct aaaaaaagaa cagtactttg gatctcagac aatcttttct
    11041 caggaattgt ttaccattca acacaaatga atgtgcagct agtagccaca tatgaggacg
    11101 gtagccccgt tcaattttca ggagatacat ttatcagttt taactctttg aaccctgcag
    11161 gaggaaaaag cacggatctt aaaggagaat atacccacta tgacaaaatg aatacaacag
    11221 attggtatgt cagaaaagat acggttcttt cagaatttaa atctttctac aacaatctga
    11281 acgtggtagg tggccaccca ggaggaagct ctaagctgac acaagcggat aatgatttca
    11341 ataatttgca tgataaatta ggagatccga agtttggtca aggtactgtg tcctttaaaa
    11401 tatctgaagc aaatccgacg tttgtgattg gttcttctaa tgttcaaacc tggtttactt
    11461 tatcttctgc gacaatcttt agtgttgtac ctgatcaacc tgaaaaaaca ggggttgata
    11521 aaaatggaaa taacgtgaac gataacatgt tgcaagtagg agacacgatt caatatcgaa
    11581 tcaaacagaa ggtgaatcga ttaggagtgg atttactagc ggtttacgat cgatttgagt
    11641 taatcgataa tttaccaaaa gaagtagatt acgtcgatgc acacgttgaa agtggtacaa
    11701 ataaaaaatt cgatgtatct ggtgaagtga cctatgacaa aacaaaacac caggtaaaat
    11761 atgcagcgaa agctgataca ttaaaaaatc gaatgaagta taacggcgaa acttacgaat
    11821 tagtgatcaa tgtaaaagtc aatgaattgg ccaatcaaaa tagtgtagcc aaaaatcagg
    11881 gaacgtcgat cattaataaa gtagaaaagg atacaaatat cattaccgtt tatttcccta
    11941 aaattccagt gaaagaagta caacaaaatg gaaaagatgt aaacggacga aatgacggta
    12001 agaagggtac gccgacagct cctttaaacg caggatctga agtacaatat ctagtcacac
    12061 aaaaatggca cacaaaaggc gtagacgctg cgtcagatca ctacaaacaa tttagtattc
    12121 aagatccaat tgaagctcgt ttgacatata aagaagtttc tgcgcaagta atagataaga
    12181 gtaaaggaaa agatattact tctgaaggca cactaaccta tgatagcaat tcaagaacgc
    12241 tgaagtggga agcttccgct gacttcttaa gtaacaatct tttagatgga cgagaaattc
    12301 agctgatatt tacagctaaa actccattac aatcagaaaa aaatattgat aaccaagccg
    12361 tagtagcagt agataatgtt tctaataaaa caaatgttgt gacaattggg gttgatccta
    12421 acttgccaca ggtcattgtt cctaaaacag gttctacaca tttagtaacg atttcagcgg
    12481 tcagcttact attacttgtg ttagcaactt ttagttatgc ggttctgaga tacatttaaa
    12541 ataaaaaaac gaaagaatga ataaaatgaa aaagttaata atagtagtta cttccttgat
    12601 tgccatgatt gttattttag tcggatgtag taatgaaaaa aataaacaaa ctaatcaaga
    12661 taatggcgta ttgaaatcag gaactatgtg gaaagaagaa gtaggtggtc ttgtttataa
    12721 tttgaaaatt atagacgaga ctacctggga atactctgag agtgtatggc atccagatcc
    12781 tgtacaaata acagtcaaga ggcaaaaaga ctataaaggt ttagaaatat acaaaatagt
    12841 agattcagct ggtgttaggg aatttataaa caaatctgat tctttattta ttgttgttcc
    12901 ctatgagaag aatggcgtaa aaaaaataat ttttcttgga tctagcaagg atgaaaagcg
    12961 aatgaaagag aaattgattc acgatggatc acaatccaat aaatataagt tacaaaagac
    13021 tagcgagtga ttgctagtct ttttatttgt cctgaaggag gaatcacagt ggcaaaagct
    13081 aaaacgccat ttgaaaaagc cgcgtctaaa atcttagaac gccgcggtgt atctgaaaca
    13141 cagtggaaac aagaagtcct tgaaaaagca caatttgacc tattacgggg aaaagacaag
    13201 gacttagaag gatatatcta tcaacgtgaa cgtgaaaagc ttgttttcga tgaaattatt
    13261 aaacactaaa aggagcgaac aattttatgt ttgaatcaat tacaatgaat tttttaacac
    13321 aaccgaaagt agtagctgcg gttgatattt ttagagcatt acaaactgcc gcaactagtt
    13381 tgaaaaataa tctgatgatt tttgctgctg ttgcggcagt ggcttccatt gctcttggag
    13441 gtattttctt cttctttggg cgaagaggag ctgaaaacgg gaagacacac gtaggttatg
    13501 tattgttggg ggtaggagtt attttagctg ccgcttctat tgtagtttca atgttctcaa
    13561 tgtttggaca aaccccacaa ggactataaa aaaacaagta gaaggagtaa aaagtacgtg
    13621 gctacttttt actccttttt ttatggaagg agaatattca tgttttttac gatttcaggc
    13681 aatgcaaaat tggataaaga gttaataaga aaagcaacga agaaagtggg aaagcgtact
    13741 tcctttttac cgaaaacaat taaatattct gtcattgaaa cggaagaaca gctacatgtg
    13801 ttaggacaag tgttagaaca agagaatcaa tcttctgtta aattgactct cacgttacat
    13861 gataaagaag gaaaaataga aaaggctggc acagaatacg tttttggctc actggattat
    13921 caaatttcag aaggttttta tcctacattg attgatttaa tccgcctaga tatatttaaa
    13981 gatacggatg aaaccatgag tgtggaagag tcttatcgaa acgaaaaaat tttacaagtt
    14041 ttagaagaag agttagaaag cgaccaaaga aaagtgaatc aagtgagtga agtcgaagca
    14101 aacgaagaag taccatggga acgcccaatc tttccaaagg atgaatcaaa agaaaaagag
    14161 aaaggaatta ttgacgaaca agctgacatt ttgactcata aatcaatatt tgaggaagag
    14221 aacgaggtaa tgggtcaatt ggaggtagat ccctttgaag aaacaatgga ggatgaagag
    14281 acggccgaag tagaagttga tccagttgaa gctaatgaag acccaacatg gactgaaggg
    14341 gattctcagg aatatattga accacttatc agtgaagaag tagagaaaaa tgaaacagag
    14401 atacaaaagg caacggtatt tgattatatt ttggatcaat atccgccaga gcatgaatgg
    14461 atgaaagaaa aaaataaatt atttttaaat gaactttatt cgaaatatca attacctcaa
    14521 acctatcaag catttttaga gagtaaagaa gaattaatct cacagggtaa aggcacactt
    14581 ttagaacagt tagagtctgt ccaatcaaca aattggcatg agcttgcaca agaagattta
    14641 ttagctactt ttgaagaacg tcaacaagaa acagatcaag aaattaatga gtatgcgacg
    14701 gaacagtcgt cgaattggga gaaagcaaaa gaggaactaa ataaagaaga acagcgagtg
    14761 attgaagaag aagtacaaaa aattaaagag cggtacgaaa agaaacgtga caatgcgtat
    14821 tccttgtgtg tagaaaagat caacaatttt actcagacga atcaagaagc attatcgaaa
    14881 gaaaaagaaa acttattaaa agaacgtata aaagaacgaa aagaagaatt ttaccgaggg
    14941 ttgcgtactg ataagctaag gattagcaaa gaattaaatg aacaactgaa taaactctat
    15001 caaactacga ctgaagttct gatggaaaaa cacgagcaga tccaacaaga attacaagca
    15061 caaattccaa aatggaaaaa agagtatgaa attcaccaac aagaattgaa agaacaagaa
    15121 gaaaaacaac ggaaaaaaga aaaagagcgc gaacaattag aactaaaaaa acgtgaacag
    15181 gatcttgcgg aacaaaaaat ggcgatagaa aaacaacggc tagaacaaga aaaggaaaaa
    15241 gaagcagctg ctcgtaagga acgtcaagaa caaatggata cattgcgaca agcacagtta
    15301 aattatctga cacatcctca accagtagct gctgttcaaa cgccagtgaa caaccaagca
    15361 aatttaactc cttcacccca gcgttccttt aacggatgga tggtgggatg tattgcaagt
    15421 ttaagcttgc ttctaggtgg aggaacagta tttgctttta atcatatcaa tcaatcttca
    15481 caggctgatt ctgtagccac aacggcgtca atcaaggaag aagcccagga acaagcaaga
    15541 aaagagtatg aacaacaatt agaagaatta ttgaatcgta ccaatcagtc aacaacagag
    15601 tcaagcatgg aaaatagcaa agagagtgat tctagtaagg ctaaagaagg atcaagcgat
    15661 tcaactgtac aatcaaacac ttccgaaagt tcagaatcaa atgaggtgaa ataatgcgtg
    15721 ttagagaaac aacgaagcga aaagacaaac gattcaattt agaaaagaat aggtatcttt
    15781 ctcatttcta tcgctatact ccctcaggag aagagctacc agaaaaacat gacaaacgca
    15841 tttcgaaaaa gattttttat agtggacttg tatacctccc tttagagtat ttagtaacaa
    15901 gagtaccaga agttttcaac cgattggaaa ttgttaaggg aagcttacaa ggaataaatc
    15961 tgtttcaatt acaggaaatg ccacaggtct ttcattttga ttcagctggt ttttggaatc
    16021 catttactcc tacaactagt ttgggtacac gtttagcaat ttcgacagtt tgtgtggttc
    16081 cagctgtact tatgggattg aaaatggaca tgtggtttcg tcctctagca gatggacaaa
    16141 aaggggataa tcgattaatg accttaaaag aaatccaaca gatttatccg caaatacctg
    16201 aaacaaaaac tacttttcca ggttatggag gtattccaat cacacattac aaaaaatatt
    16261 ggtacattca aacagatact gttaatacgt gtattgttgg tacctctcga tcagggaaag
    16321 gtcagattga agtgttagcc accattgaca atttatctcg tgcagaaaaa caaagttcaa
    16381 tggtcgttaa tgatccaaaa acagaattat atgttggtag taaagatgaa ctagaagcta
    16441 gagggtatga tgtatatgcc tttaatatca ccgatccact gcaatcaatg agtgataatc
    16501 cattggcact catcgtgaaa tactggaaac gaggagacat agatactgca acacagttaa
    16561 ccaatacttt cacaaatacg atttattatg atgccaacgc ttcagataac aaatacttta
    16621 acgaaaacgc gcagaaagct gtcaatgcgc ttatttttgc gttgttagaa caagctgatc
    16681 aaacaggaga ttactccaaa ttgacaccga ataatctcgt tgagcttctt tctgagattg
    16741 gcggttttaa ttattatcca gatccagaca atgaattcaa acagttgaat gccttagatg
    16801 aatttatgaa tcagttgcca cctggaaaca ttgcaaaaaa acaatatggg gcaacgaaaa
    16861 ttggatctga taaagcgaag ggaaatattt tatcaacggc aatcacggga ttgaatccat
    16921 ttactctaac gaaaattgca aagatgactt ctcaatcaac gattgattat aaatcggttg
    16981 ggtttccaaa atacttagat ttgaaattac atgaaagtct tttaaatcaa cgagtcgtag
    17041 tagaatttta tcataaggga aagaaatttc atgaagaacg tgtcaaagta ggctataaag
    17101 gatttagtga aatcaatttt gattgtcatt tagttgcagg tgatcaagtt tgtttaaaat
    17161 acgatcatca aggaaaagaa tatgtggctt ggtatgaatt ttctcaaaga gtattgaaag
    17221 acgaagaggg taatatcgtt tatcggaaaa aacgaggaga aacccatttg ccagaattag
    17281 aaaaagaagc cgttctaaca ttagatgagg aaaaaagtaa cttattagta gagtctattc
    17341 ggatgcacta taccgataaa ccaatggcta tttttatgct tacacctgat tatgatccat
    17401 ctaaccatat cattgttagt atttttctta gtcagttata taaagaatta tctacgcaat
    17461 gtgttaagac taaaggagat aaatgtcacc gcaggattca ttttatttta gatgaatttg
    17521 ggaatatgcc accaatggat aatatggaag gaatcatgac ggtcacagct ggccgaaaca
    17581 tgttgtggga tctgtttatt caatcttatc agcaacttta tgcgaagtat ggagaacaaa
    17641 acgcagcgat tatcaaagaa aattgtcaga cacatattta tattatgtcg acagatgata
    17701 ataccatcga agaattttct aaaaaagtgg ggaataagac ggttgaacaa gagaacagta
    17761 ccatcaattc attaggtatg aatactcata tcaatcgcaa tgttgattca gatcgtatct
    17821 taactcctga aagaatttct acttttttag aaggtgaaac gattgtactc gctcctttaa
    17881 aacgacaaga tttgaaaggt cataaaatac ggccgtatcc tatttttaat catggggaaa
    17941 cgaatcttcc ttatgcttat caatatattg aagatttcaa tccatcgtgg gatatcaatg
    18001 atatagacat acattgtaca catgcggact tggatcttaa ggctttacaa attgattatg
    18061 attatttcct accagatgaa tatgctagaa atctctatca tggactgcat gatcaattag
    18121 aagaaaaaaa cgaagaaaat atgttttata aaatcgttca atctcttgag aatgagacgg
    18181 ctaaaaaatt gttaattcaa ttttacgaag aacaagcagc agatcgactt caagaatatg
    18241 ttgaaaagtt gatcaaaaat gaagaaattt ctgaaatgat tgggaaacgg ttgttattgg
    18301 aatctgaaaa ggtggtgaaa gaatgatcat tggaggaatt ttttctggca tagccgactg
    18361 gtggtcaggc ttattcggag aaggggatgc aaaccccaaa accgtaacga aagtcttaca
    18421 agattatggt aattatctgc agtatcaaga tgtgttcagt tggatttgta atactttttt
    18481 atgggggttg atcaaagggt tatataatct caatacttta ctagaaaaaa ccatttatca
    18541 aagctttgat ttaaaagact tattgaacgc cgctggggta aatgaactat ttcaaagttt
    18601 gattagtaag gtattggctc ttttttgtgt cgtcacatta atttatttag gcttgaaatt
    18661 ttttatgagt aaacacccac caaaagtcaa aaatatcttg gttaatttat ttatggccat
    18721 gatcttgatt tttggtggta gttctttaat cgatgaaggg ttaaatatca gtaaaagctt
    18781 ttacggagac gtcactgcag caaataaagc agataaaacg ggttcacctg cttttcaaat
    18841 tattcaaaat aatgtgatcg atgtcagtac attactagca actgacccga ataaagtaga
    18901 atccctgcca acagacaaaa gaaatgcttt aacagcgaaa aattttaaaa cagcgaatat
    18961 caatgggatt attactccta aacaagctaa agaaatggcg gataaagata agagtggttt
    19021 atcagattta caaaaggatc ggttaagagc gttacaatac cgactggaac tggatgataa
    19081 tggaaaagaa attcctgtgc aaatcagtga tgaaggctta gccaaatatg tttatacttc
    19141 agggtatcgt cgatacatta gtagtccagg gattatttta gctggtgaat cttctttggc
    19201 ggtggcctat ttatttatcc tatttacgat cgttacttgc attattgagc tggtatttaa
    19261 aaaattctat ttagtgattg ccgcgtcaac ggactttgag acaggacaac ggatgaaaag
    19321 tgctatcgaa gatatttctc aatccttctt gttattggca tttacaattt tagaattacg
    19381 aatctatacc ttaatgcttt caggtattgg tgatttgcat gcggcaggaa agatcaatgg
    19441 attcttgtat gttgtcgctt tgattgtact aaccattgcg ctattcaaag gctctcaatc
    19501 agttacgaaa attttcggcg ttgatacgag tctgaaaaac ggcagtaatt ctcttcttag
    19561 catgtttgcc ttaggaaata ttgcgaaaaa tgtgggtagc ggagctaaaa accttgcaag
    19621 tgctggtaag agtggtttaa gccatttaaa tgatattcgt aaaaatggat ttggccatcg
    19681 aaaagatgtt acccctgata acggggaaga acaatcagac gataaagcta caactgtacc
    19741 taatagtaag aaaacagttt ccgaaatgtt cgggaaagcg aaaaatggtg tttctaaagc
    19801 cgcagaaggt cttggttacg tcaatgaacg tgggttaaaa ggaacagctg aagatcttac
    19861 agaaaaagcc aaagacacct tagaagataa attagacggc acgagagcta aagaattggc
    19921 tgaagctgtg aagaatccat ccgaagcact agaaaaacaa aaagaaaaag cttcagaagt
    19981 caaagaagga ctaaaagatg cgtatggtga aggacaagtc aatgcagcag tgaaagctaa
    20041 tacaacaacc gaaaaagaaa atcaagaagg tatagtgatt ccttcagtca aagatcacca
    20101 agaagcgttg cactctaatg aaaattcgat tgaagagaaa aattccatag aagaaagaaa
    20161 ttcagaagaa ggaaaaaatg gacagttacc aaaaactgat ccagaacaat atcgctataa
    20221 acctaacagt gaccttgaaa atgagaagcg aatttcagat ttatcaaaag taaatcaaga
    20281 agacaaagca gaaaatgagg gacagttacc aaaaactgat ccagaacaat atcggtatag
    20341 atctgttaac tccgaaaatg aaaaacgcat ttcagattta ccaaaacgaa atcaagaagt
    20401 acaaacggat gaggattcca tcgttctgcc aaatgataat ggaatcgaag ttggaactga
    20461 aaaatcaacg aaaattggtt tacctaaggc acaaaattta ccaatgaaag atagtcgttt
    20521 gaatcaattc aaggataatg atcaaagttt tgttcatcaa tcacctgcag gtactgttca
    20581 aatgaaacca agtcgtttgc ctgaaaatgg aaatctgaca actgtttctt acaatttatc
    20641 tgaaagtggt gagacaggga atgcgtccgt tcaaaatgtt gtgacaagag aagctgcacc
    20701 aaaacctatt caaaacgttc atacaggtta caagccagca aatgtggcat ttactgcacc
    20761 aacaaaaata aatgtgacaa gagaaactaa aaacaggaac aatgcattga aagaacaact
    20821 attgagggat atcaaacagg atatcaaacc ataaaaggcc tacaagttag gccttttctt
    20881 tatatgaaaa ggagaaatca attatggata aatatataaa catgaaaaac cctccaagat
    20941 ttagtggaga atggaagttt ttcgcttttt tctttttaga tctattaacg cttggtggct
    21001 gctttttttg ggcgaaaatg gtcaataatc ttgtccactt accactcttt tttgcactct
    21061 tgaattatgg cttatggatt gcgatagcgt tagtgattgt ttggcgaccc tataataacc
    21121 caggtcaacg acaaattttt gcgattatcg agtctatttt ttttgcggac aagaaccatt
    21181 atcatgcgtt agatcctaac cgaaattatc atggtacgta taaggaggat gaataaatgc
    21241 gagtcaaagg acaaaattca gttgaaagga aatccatttt gcagtttgga aaaccagaag
    21301 agcgctctat cttggactta tttccgtata aatcctgtac agaagaggga gtcttaatta
    21361 ctagagaaga tcattttcaa cgttattatc gtgtagtttc tacagacgtg gaaggattaa
    21421 atgaacaaga gaaactagaa cgaatgaatc agttgaccac cgtcatgcgt acgtatgtgc
    21481 caacaattaa gttagttagt ttgaccacag agacggatct aacggaacaa atcgtgcaaa
    21541 agcggcaatt attagataaa aatcgtatgg aacagtcctt aggaagaaat ctacaacgat
    21601 taaaaaaata tgaaaagaaa ttagtcgaag aaatccagga attgaaacga gcagaacaag
    21661 aacgtcctga cttaagcttc tttttcgtca ttgaaggaaa gacaatcaag gatttacaaa
    21721 ccagaaaccg tcagttaatg cgatctagtg gcattttagg gttaaaacca ctctacaaaa
    21781 aagaattgat caagattctg tatcgaatga acaatatgaa tgatgagtag gaatggagaa
    21841 gagagaatga aatatccgtt gatatggtta gaaaaagatg ttccgaagga agagaccact
    21901 agaaaatttc ctcacacttt aagcctgggt aagttgggaa aagggcaatc ttttaaccaa
    21961 gtaaagaatc aaacaagaag aggtgactgt acatgttaga agcaattaaa acagcttttt
    22021 caccacaaaa tgatcaaaaa gtacttgatc cattaaagca actaggaaat cgggaaatag
    22081 aaattttaaa atccaaaggg tatgatttag attttttaaa acaagtgatg ccacaaggtg
    22141 ggttaaattt tgatgaagaa tatgtgacgt atggtaatgg ttattcacga tgtgtgacag
    22201 tttatcacta cacaaaaaat cctacgcttt tttggttggc caatctcatg aacaatcctc
    22261 atacagtggc cacactcgat gttagcacag atgaaaagca aaaagtgatt gatcaaatca
    22321 atcgtgcctt agatgaatta aatgatcgat cagataacga acgaaaagcg actgaccgaa
    22381 ataaaagcgc agaagaatac ctggaactag cggaatatgc tcgtaaattg acttctaatg
    22441 gggaaatttc taagcaagtc aaagtgagag tacatgttta cggaaacacg attcaagaag
    22501 tagatgaacg agcgcaggaa ctgatcgaaa atctcaaagg gatggattat cgtgcggtga
    22561 cttatctgca taaaaccaaa cgagattggc aatcgatgtt taccatgttc gatgaacaag
    22621 ctgaatggtt cggaaatatc aaagggcaat cactaccatc gttaaacatt ggcggaggtt
    22681 tcccgttcca ccaccaaacg ctaaaagatc caggagggac acaatatggg gaaactatga
    22741 caggcggccc atttgtctgg aatgcgacgt ataaaaatag tgtacggttg tctaccaata
    22801 ccttgcttct aggaatgatg ggagctggta aatcgaccgt tcttaaaatg atcgcggaag
    22861 cccatttagc tgcaggagac tttatttggg gctttgaaaa gggaaaagac tttattcctt
    22921 tcttaaagga atataacggt attatggtgc gtttagacgg atctgacgga atgatcaatc
    22981 ctttagagat atttgccaca cggacgtatg atgaagcatc cagtttatat gacgatggat
    23041 cagtcaaaga tttgaagatc aatgaagcag cgtcctatca aacacactta gacaaagtgg
    23101 tctatcaggt acagttagtg agtcctcagc taaaaggaac gatgaaagca gaatttaaga
    23161 cctacttaaa tcgtttttat gaagagtatg gaacagtacc acgcggcttt acttcctcaa
    23221 attcgcgttc aaatactgat acgcaagtca cagggaaaga tccagaagct tatccgacgt
    23281 tcaaagaatt tttagacttt ttaggacaac tggaattacc aggtgcttcc caagagaaaa
    23341 agaatcgaaa agaagaaatg gaatccatcg tagaatcctt atgtgagacg tatggcatga
    23401 tttttgatgg tcatagtacg attcgacacc ttgaccaaca acagttggtc ttttttgaca
    23461 ttgactctat tacaggctta gatcgagggg tacaacaatg tcaaatgtac atggctatga
    23521 cgttgatttg gaatcaggca ttgattcaag gaagaagaca acgacgttta attaaagaaa
    23581 aacaaatgga agaacaagac ttcaaacgct tcttggcgat gattgatgag tgcca
//
LOCUS       DACBYO010000039        23463 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.039, whole genome shotgun sequence.
ACCESSION   DACBYO010000039 DACBYO010000000
VERSION     DACBYO010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.039"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            155..1105
                     /locus_tag="IVD26_001478"
     CDS             155..1105
                     /locus_tag="IVD26_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6079464.1"
                     /translation="MTLCQLYAKQNAQRTNVKKSTQKQREQLMRLLKEDKLGARSIDT
                     IKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFYIAIQDDYVRKNPFDFKLSEVIEN
                     DTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLILLKTGLRISELCGLTVADIDFKN
                     EVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSKETIQAFQRVINSRPKIKSIEVDG
                     HSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHKDNPLPHITPHTLRHTFCTRLASK
                     NMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEVQRLIA"
     gene            complement(1112..1270)
                     /locus_tag="IVD26_001479"
                     /pseudo
     CDS             complement(1112..1270)
                     /locus_tag="IVD26_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788611.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-binding domain-containing protein"
     gene            1310..2449
                     /locus_tag="IVD26_001480"
     CDS             1310..2449
                     /locus_tag="IVD26_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAP6079465.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            2442..3242
                     /locus_tag="IVD26_001481"
     CDS             2442..3242
                     /locus_tag="IVD26_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP6079466.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            3242..4069
                     /locus_tag="IVD26_001482"
     CDS             3242..4069
                     /locus_tag="IVD26_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP6079467.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            4047..4781
                     /locus_tag="IVD26_001483"
     CDS             4047..4781
                     /locus_tag="IVD26_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP6079468.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            4881..5747
                     /gene="rfbA"
                     /locus_tag="IVD26_001484"
     CDS             4881..5747
                     /gene="rfbA"
                     /locus_tag="IVD26_001484"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAP6079469.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            5761..6333
                     /gene="rfbC"
                     /locus_tag="IVD26_001485"
     CDS             5761..6333
                     /gene="rfbC"
                     /locus_tag="IVD26_001485"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAP6079470.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            6355..7383
                     /gene="rfbB"
                     /locus_tag="IVD26_001486"
     CDS             6355..7383
                     /gene="rfbB"
                     /locus_tag="IVD26_001486"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAP6079471.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            7481..8332
                     /gene="rfbD"
                     /locus_tag="IVD26_001487"
     CDS             7481..8332
                     /gene="rfbD"
                     /locus_tag="IVD26_001487"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAP6079472.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            8366..10399
                     /locus_tag="IVD26_001488"
     CDS             8366..10399
                     /locus_tag="IVD26_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079473.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            10443..11723
                     /locus_tag="IVD26_001489"
     CDS             10443..11723
                     /locus_tag="IVD26_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAP6079474.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            11933..12739
                     /locus_tag="IVD26_001490"
     CDS             11933..12739
                     /locus_tag="IVD26_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079475.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            12751..13971
                     /locus_tag="IVD26_001491"
     CDS             12751..13971
                     /locus_tag="IVD26_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079476.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            13961..15547
                     /locus_tag="IVD26_001492"
     CDS             13961..15547
                     /locus_tag="IVD26_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6079477.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            15586..17724
                     /locus_tag="IVD26_001493"
     CDS             15586..17724
                     /locus_tag="IVD26_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP6079478.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(18092..19075)
                     /locus_tag="IVD26_001494"
     CDS             complement(18092..19075)
                     /locus_tag="IVD26_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HAP6079479.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            19453..20844
                     /locus_tag="IVD26_001495"
     CDS             19453..20844
                     /locus_tag="IVD26_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP6079480.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIGASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            20860..21900
                     /locus_tag="IVD26_001496"
     CDS             20860..21900
                     /locus_tag="IVD26_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP6079481.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            21919..23004
                     /locus_tag="IVD26_001497"
     CDS             21919..23004
                     /locus_tag="IVD26_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAP6079482.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            23037..>23463
                     /locus_tag="IVD26_001498"
     CDS             23037..>23463
                     /locus_tag="IVD26_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAP6079483.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQK"
BASE COUNT         7691 a         3842 c         4799 g         7131 t
ORIGIN      
        1 agacgcattg ggaaacacaa aatatgtgta tgcttggaga ttgacaccca cagacccgac
       61 accaaaggga aaacgggaaa aaccctcact tcgagaactg gaacagcaga taagacggga
      121 tattgaggac ggtatcgaca gcacaggcaa gaaaatgacg ctttgccaac tctatgccaa
      181 acagaacgca cagaggacaa atgtgaagaa aagcacacag aaacaacggg aacaactcat
      241 gcggttatta aaagaggaca agttaggtgc taggagcatt gatacgataa aaccctctga
      301 cgctaaagaa tgggcgttac gcatgaaaga caaaggcttt tcctacaata ccattaacaa
      361 ccataaacgc tcgttaaaag cgtcattcta catagccata caagatgatt atgtgaggaa
      421 aaaccctttt gatttcaagc taagtgaagt catagaaaat gataccaaag agaaagtcgc
      481 attgacagag gaacaggagc aagccttatt gtcatttatt aagacggaca acgtgtatca
      541 caagcattat gatgatgtgc tgatactgtt aaagacagga cttcgtatct cggaactgtg
      601 cggactgaca gtagccgaca ttgatttcaa gaatgaagtt gtgattatcg accaccagtt
      661 actaaagagt aaggaacagg gctattatat tgaaacgcct aagacgaaaa gcgggataag
      721 gcaagtgcca ttaagcaaag aaacgataca ggcatttcaa cgggttatca acagccgacc
      781 aaagataaag tcgatagagg tagacggaca cagcggtttt gtgtttatca atccgaaagg
      841 taatccaaaa gttgccattg attataacgc cttatttatc cgtatggtaa agaaatacaa
      901 caagcaccac aaggacaatc ccttgccaca tattacaccg catacgctac gccatacatt
      961 ctgcacaagg ctggcaagca agaacatgaa cccgaaagat ttacagtata tcatggggca
     1021 ttcaaacatc agtatcacaa tgaactggta cgctcatgcg tccatagata ccgcaaaatc
     1081 agaggttcag cgtctaatcg catagaagta tttaccacga ttttaaccac gattgacagg
     1141 gaaaatataa gaagatagac ctagatatgc gaggtttacc acaaaagcaa aatgcccgta
     1201 gagccgataa aataaggctt tgcggacatt tgagaagata taaaaagata gtcaaaaaga
     1261 catatataat ttataataat tatgactctt aattaaagta ggtgcccata tgcttgtttc
     1321 ttttagtatg gttataagat tttttctgac aattttatta tcactgatat taacacctgt
     1381 attcaaaatc atttcagtac aaacaggtat ggtcgacaaa ccaaatgaaa gaagaataaa
     1441 taaagttcca atgccttcag cgggcggact gcctatcttt atttcatttg ttatatcgac
     1501 tttattctta ttccgtaaaa ttatccctca atcgtatatt gtaccgatct tgattgcttc
     1561 tttagtaatc atagtcacag gagtgctcga tgataaatat gagctgacac ctaaacaaaa
     1621 aagtataggg atcttgattg cttctcttat tatttatttt gtagcagata tacgtattga
     1681 ttccttcacg cttcctttta ttggatatat ccaactaggc tggcttagtt ttcccgtaac
     1741 gattttttgg atcttcggta tcacgaatgc ggtcaatctg attgacggtt tggatgggct
     1801 ggcggcaggg atttcattga tcggtttaat tacgatagga atcattggat attttttcct
     1861 ccatgcttct acagtgtata ttccagttgt tattttctgt cttgtagcaa gtattatcgg
     1921 tttttttcct tacaattttt atccggcaaa gatttattta ggcgatacag gagctctatt
     1981 cctagggttt atgatggccg tcctttcact acaagggctg aagaacgtga cttttgtttc
     2041 atcgatttct ttgctgatcg tcatgggagt gccggtaaca gacacgtttt ttgctatcat
     2101 taggagaaaa gcaaaccgtg tttctttttc tacagcagat aaaaaacatc ttcatcaccg
     2161 actaatcagt ttaggcttta ctcataaagg tgctgtcctg acgatttatg cgatggcttt
     2221 gatgttttct ttcacagcta tggtcatgaa ttatactgga agaatcggaa cgatcatatt
     2281 gattattgcc atgttgtttg ctgcaatttt attatttgaa ttgattggtc tgatcaatga
     2341 gaaacatcag tttattttaa aaacattgcg atttttaggg aataaagagt accgtacgca
     2401 agtaaaacag aaatatttga agaaatggaa ccgtcatata gatgaataac aaattaaacc
     2461 agccgatcct tattagtatt gtgacggcaa acagtgataa aatttttcgg acactagata
     2521 attttatttc aactgtaaaa gatgaaacag cagtaaaaat ccgaattttt gacaacaatt
     2581 cacttcccga gtacaaaaaa agactaacag agtataggaa atatccctac atcgatatct
     2641 attttcatga tgaaaattcc ggatttggtt atggacataa tcacaatctg atagctagcg
     2701 attctcgcta tggcattatt tgtaacccag atattttagt ggatgaagag acagttacag
     2761 cattggtctt gttattgaaa gaacatccgg aatgtgcgat gttagcacct aagattctta
     2821 atgaagatgg aacaactcag cacctcatcc gtgagcagct ggctgttttt gattacgttt
     2881 tgcgctttgt gcctttcaaa tgggtcaaaa aaaagtttga caaacgactg gctgtgtttg
     2941 aatgccgagg attgcctact gatgctaata gttatgtacg gatgatctca ggtagtttta
     3001 tggtagctga tattgataaa tttaaagaga taaaggggtt tgatgagcgt ttcttcatgt
     3061 actttgaaga caacgacttg tgtttgagtt ttgaaaaagc aggttacaag ttattgtaca
     3121 caccctttta tgcagttatc catttttacg ggaagggtgc gcatcgaaat gcaaaactgt
     3181 ttcgcgtgtt tttgacttct atgatgaaat ttttcaataa gtgggggtgg cgttttttct
     3241 gatgaaacca gaaatattag tagtcgttgt gctttatcag caactattca gtcaatctcc
     3301 agcttatgga ccattaagca aagcacttag cgaaaagcaa attcagctta ttatttacga
     3361 taatagtcct caaaggcagc aaaatgagct gtttgaaaaa gaaaatatcg tttatcatca
     3421 tgatccgcaa aatcctggtt tagcggtggc ttataatttt gcgttgtctc aagcagatga
     3481 aggaacacgt tgtctcgtca ctctggatca ggatacgagg ctagtcgacg attattttga
     3541 actattgcgt aaagtaacct ttacagatga atgtgttgct gcagttccga tgattttttc
     3601 tgggagccga caagtttctc ccctatattc agatcgttat atcaatcgta cagctcaagc
     3661 agtagaagtt gaaggcccaa cagctgaacg aatcatggca atcaattcag gtgttgcctg
     3721 gtctgtcaaa tttctaaaaa agattggcgg gtttaatcct gctttttctt tagatttttt
     3781 ggatcattgg ctgttttgga aagtggatca gttggaaaaa actgtggaga tccttcctgt
     3841 acgaatggaa catgatcttt cggttttaga ctatgaaaaa gtttcaagta atcgataccg
     3901 ttctatttta caagcagaaa atcgatttta tcatgaatat gatcaaaggc atttatccag
     3961 tcaccgacga caattattgt taagaacagc taaacagttc ttgaccgtca aaaaccggca
     4021 tatctggcgg atgactttgc gctcatatgt taagaattgg aaggtgtgaa ttcgtgcgtt
     4081 cggtttgtat agctaccttt aatggaggca gatatttaag agagcagtta gatagtattt
     4141 tatctcagct ttcagcagaa gatgaagtag tcatttctga tgatgggtca gtagatgata
     4201 catgggatat attaactgaa tacgcagaaa aagataagcg aatccagctt ttttcggggc
     4261 ctcgtcaagg attgatcgct aattttggtt atgcgatcca gcagacgaaa ggagatctaa
     4321 tctttttggc agaccaagat gatgtttggt tggagacaaa agtgaaaaag atcactgact
     4381 attttgagca gaatccggat cagctagtag tagtttctga tttaatcatt gtggacagcg
     4441 agctgcaaga gatccatgat tcgtattttt cgtttcgaaa ttccaaagaa ggatggctta
     4501 ataatgtgat aagaagtcac tatattggtg ctggtatggc tttccggtct tctttaaaac
     4561 ccgatatttt gccgatcccg tcagaagtgc cgatgcatga tatgtggatt ggtttgctgg
     4621 gaggaaagaa gactgggttc ctaagagaac cgttaactct gtaccgaaga catgatttaa
     4681 acgcgagtga gattgaaaca cattctaaat tacggcaaaa aatttcttgg cgtgttcatc
     4741 tgattacggc gttgatcaaa cgaaaatggt ttaaacgttg ataaaagatg tttaaatcct
     4801 taatatttcc atgacaaata taacaattga tgagataata acaaagtgaa atttgaaatc
     4861 aaaaaggaga gcagatatcc atgaagggaa tcattcttgc tgggggcagc ggaacacgtc
     4921 tgtacccttt aacaaaggca acatcgaaac aattgatgcc gatttatgac aaaccaatga
     4981 tttattatcc aatgtctact ctgatgttgg cgggaatcaa agaaattctg attatttcaa
     5041 cgccacaaga tacaccacgt ttcaaggaat tatttggaaa cggaaatgat ttaggactgc
     5101 agatcgaata tgcagtacaa gaaagtccag atggattggc acaagcgttt atcattggag
     5161 aagaatttat tggagatgat agtgtctgct tggtattagg ggacaatatt tactatggtg
     5221 gcggtctgtc taaaatgttg caacgagcag cttcaaaaga tacaggcgcg acagtatttg
     5281 gctatcatgt caatgatcca gaacgctttg gtgtagtaga atttgatgag aatatgcaag
     5341 ctttgtcgat tgaagaaaag cctgctcagc caaaatcaaa ttacgctgta actggccttt
     5401 atttttatga caatgaggta atttctatcg ctaaaggtat caaaccttca gaacgtggag
     5461 aactagagat tacggatgtc aataaagcat atttggataa aggaaaacta tccgtagaac
     5521 ttatgggacg cggatttgct tggcttgata caggaacaca tgaatcattg cttgaagcat
     5581 ctacctttat cgaaacaatt gaaaaacgtc agaacttaaa agtggcttgt ttggaagaaa
     5641 ttgcttaccg tatgggctac atcgataagg aacaattgct ggcccttgca cagccattga
     5701 aaaaaaatca atacggtcaa tatttattga atttggccgc tgaataagga gtccttacag
     5761 atgaaagtaa cagatacaaa attaacagat gtcaaaatcg tagaaatgga cgtctttggc
     5821 gatcatcgcg gtttcttcac agaaagttat tcaaaagcaa aatttgcaga acatggattg
     5881 aaatatgact ttgttcaaga caaccattca ctatcagctg aagctggtgt ccttcggggg
     5941 cttcatttcc aaaaaggaga agctgcacag acaaaattga ttcgggtagt cactggagca
     6001 gttttagatg tagtagtgga tatccgcaaa ggtagcccga cttatggtca atgggacgga
     6061 tttatcttat ctgaacataa tcatcgacag ttgcttgtac ctaaaggata tgcccatgga
     6121 ttcgttactt tgacaccaaa tgtgaacttc ctttataagt gtgataatta ctataatgca
     6181 gaagcagatg ggggcatcgc atttgatgat ccagatttag cgattgattg gccaattgat
     6241 ccatcaagag cgattatgtc ggaaaaagat caccgtcatc cgacattaaa agaatttgaa
     6301 gcagaaaatc catttgttta cggagaaatc taagaattaa ggagaaattt tcttatgaaa
     6361 aacatcattg ttaccggagg tgccggattc atcggctcta atttcgttca ttacgtggta
     6421 aacaatcatc cagaagtgca tgtcactgtt ttggataaac tgacttatgc aggaaacaaa
     6481 gagaacttgg ctggacttcc tagcgatcgc gtagaattgg tcgtaggaga tgttgcagat
     6541 gcagaattag tggaccgtct agtaaaagaa gcggacgcag ttgttcatta cgcggcagaa
     6601 tcccataacg ataattcatt aaaagatcct ttcccatttg tacaaacgaa tatcattggt
     6661 acgtatacac ttttagaagc ttgccgcaag tatgatgtac gctatcatca cgtatctact
     6721 gacgaggttt acggcgatct tccattacgt gaagacctgc caggacatgg ggaaggcgaa
     6781 ggagaaaaat tcactgcgga aacaccatat aatccttcaa gtccatattc ttctacaaaa
     6841 gctggttcag atctgttagt aaaagcatgg gtgcgttctt ttggcttacg tgcaaccatt
     6901 tcaaactgtt caaacaacta tggtccttat cagcatattg aaaaatttat tcctcgccaa
     6961 gtaacgaata tcttaagcgg tattcgtcca aaattatatg gcgaaggaaa gaatgttcgt
     7021 gactggatcc atacgaatga tcattcttca gcagtgtggc tgattttgac gaaaggcaga
     7081 attggcgaaa cctatctgat cggtgcagac ggtgaagaag ataataagac cgtgatggaa
     7141 ttgatcttag aaatgatggg tcaaccaaaa gatgcgtacg accatgtaaa cgaccgtgca
     7201 ggacacgact tgcgttatgc aatcgattcg acaaaattac gggaagagtt aggatggaag
     7261 cctgagttta cgaacttccg tgatgggttg gctgacacga tcaaatggta cgaagaacat
     7321 gaagactggt ggaaaaaaga aaaagaggcc gttgaagcag catatgccaa aaatggacaa
     7381 taatacagag aaaatgtcac tgtattaatg gaaaaacaca tgtgaggcag gcgctcgcct
     7441 gtctcttttt taaaataaaa atcaaggagc ggataatcat atgtttttat taactggagg
     7501 aaatgggcaa ctaggtacag aattgcgcca tttattagat gaaaaaaatc tgcaatatgt
     7561 ttcaacagat gcaaaagact tggatatcac agatgccgag aaaacaatgg cttacatcac
     7621 agaattaaaa cctgatgtta ttttccattg tgcagcttac acagcagtag ataaagcaga
     7681 agaagaagca aaagaattag atgagaagat caatgttgat ggtacaagaa atgtagcact
     7741 tgcagcaaaa gctgtgaatg ctcaattcgt ctatatcagt acagactatg ttttcgatgg
     7801 aaaaaacaaa aatgtagaat acgaagtaga cgaccaaacg aatccactaa atgaatatgg
     7861 tcgtacgaaa ttattaggcg aaaaagcagt agaagagatt ttagaagact attatatcat
     7921 acgaacttct tgggttttcg ggatctatgg acacaatttc gtcttcacga tgcaacgcct
     7981 agcggaaacc cgcgacaaac tgactgtagt aaatgaccag tttgggcgac caacttggac
     8041 acgtactttg gcagaattta tggtatatgt catcgaagaa aaagcaccat ttggtattta
     8101 tcatttgtcg aacgaaaata gctgttcttg gtatgaattc gcaaaagaaa tattgaaaga
     8161 tacagatgta gaagttgcac ctgttacgtc agaagaattt ccgcaaaaag caacacgtcc
     8221 gcagtattca gtcatgagcc tgaaaaagac agaagagtta ggatttgtca taccaacttg
     8281 gcaagaagca cttgcgcaaa tgctggaagc tgccaaaaaa atgaataagt aatttccttt
     8341 tatcaaatag aatttggagc atgatatgga aaaacaaaca agaagtgcac gacgaaaaga
     8401 aaagccaaaa gcgaaccagg cagattcgaa tttggtgctt gacctgtttc taaaactccg
     8461 ctatcttatt ggcgttttag tcatcgtggt catcgttact tttaatttaa acggaagttc
     8521 acttggtgtt tgggataaat atgtgtcgca aagagacgat gggaaaaaaa ctgatgtgat
     8581 ttttggacag aatcgggaag tgcggtcaga cgaatggctg gtgcagacac ctttttacct
     8641 ctcacaagct gaagaggact ttccgttggt gaacgaggat tattcattaa acggacaaaa
     8701 catgatcatt gcgtataatt ctcctgtaaa ggatattacg gttatcggaa aaccattcaa
     8761 ctggggattc tttttcctcg gaagagatcg aggactttcc ttttattggg cgatgaaatt
     8821 agtcgtcatg gtcttgcttg gattcgaagt actgatgata ttaacgaaga gaaaaaaagc
     8881 tctatcgcta atcggtgcat ttgcgctgac attttctcca gcagtccagt ggtggttcat
     8941 gcaacatgtg ggcgatttga ttttctttac tttgggactg atgactgctt tttatcatta
     9001 tttctacaat catgataaaa aatggctacg aacgttgatg atgcttttgg tggttatttt
     9061 cggtattggg tttattttag tgatttaccc agcccatcaa gtgatgctgg cgtacttgct
     9121 gattttttat tttgttggcc tgcttattta ctatagcaag aaagtttcat gggatctgtt
     9181 ggatgtagtg ttgattggag gggcagtttt atttattggc ggagtcatgg ttcatttctg
     9241 gctaacgtca aaagacgcat tgttagcttc tttgaatacc ttatatccag gaaaacgggt
     9301 aagtactgga ggaaagtgga cgattggcga atttttttct ttccttacaa attggaaaat
     9361 tccttttgaa gatatcaact attcgaataa ctctgaagtg gccctgttct atcacttttt
     9421 tccaactgta ttcctagcaa gtccatttgt gttatttggc aaaaaagata gcgaacaaaa
     9481 gttactggga cgtattttga tgattttttg tctgttttct atcttttgga ttaccgttgg
     9541 gttgccaaaa tggctagcag aaatcactct gctgtcttat gttcctccat taagagccat
     9601 ccttactttt agttttgcgg cttgtttatt atcgatctgg tttatcgctt atatttggag
     9661 agaagatgtt attcctattt ggtataaatt cattttgttg gcagtaaatg catggtctta
     9721 tttctatgcg attacgcatt cgaaaatgga taattatttt tcggattttg aaaccatcgc
     9781 agttgctgtg ttgggaacag tgattttagc ttttgcatta tttggctgga gacgcttgtt
     9841 ttacctcgct tttgccgcct tagttatcgt atctggcttt ttcgtcaatc cagtcgtaga
     9901 aggtacagga gcgatttttg aaaaaacact ggcaaaagaa atccaaaaaa tcgatcaaca
     9961 agatcctggt aaagtttggt tgtctgaaga tgaattatat aacttcaccc caacattggg
    10021 agtgaaatcc ttcaatacag tacgctttta tccagatata gctgcatgga agaaaatcga
    10081 tccgaaagaa gaatacgaga agtattataa tcggtatgct catacaagag cttttatcgc
    10141 taaggaagat acaaagttca ttttagatcg tccagatatg ttttcggtca cgttgaattt
    10201 tgaagacgca gaaaaattag ggatcgacta tgtgatcagt aaacgaccat taactgatta
    10261 caaccaatta tatgaagcgc agttcacgca gctatatgga ccggataaag acggttatat
    10321 gatttttaaa gtagaatatc cggattatcc agatgtacca caaacacaaa ctcaggaaaa
    10381 tcagctagtc gtacagtaat aggctagctg agaataatcc tgaaatgtta gtagaaagga
    10441 gagtggagat aattcaagca atcgtacaaa aatttgtcaa caaaatgagt gtcggtttct
    10501 tgcttttgtt actgacgcta gtcttttttg tttggacagc agggttaggt tttccagcaa
    10561 ctttgtttat atataacaat agttcattac ttatcgcttt tagtgtggct attttgctca
    10621 ttttaaatgt ttataaagca aaaggcgtcg attttcttta tctaggtgtt gcgcttgccc
    10681 ttttcatttt cttttcttac tttcgggaat taagaaatga gtctttattt ggagacttac
    10741 tgtttccttt gattatttta ttttgtttag taattaaatg gatcgagtgg acaaaatggg
    10801 atcgcggtat ttatctgatt gtcttttcgg tcttcctcgg aatcacgtta tatcgtgtat
    10861 ttacagagat ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg
    10921 atatttggat caatacgaat ataatcggaa gttctttgat gactcttgct ttattgatca
    10981 gtggatttgc cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg
    11041 ttgcagcttt tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg
    11101 tttttgcgat attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta
    11161 ttgcttacac ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg
    11221 aaaaagtcaa tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag
    11281 gagaaaaatc tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc
    11341 aatttttagg aaaccacaat agttataatt ctattttgaa tatctatgga ttgataggat
    11401 ttgggattgc tgctttgctg cttatccttt ttattggtcg cttaacgttg aaagcagatt
    11461 tatccaacgg gcagatgact tttatctggg ccttttttgc ggtgatgatg cagtcattta
    11521 tggaggatac attgacttca tacccatggg ttccgattat ttatatcctg ttggctatgg
    11581 ccgttcatcg atatgatgaa ccagaagttg cggaggaatt ctatgttatg gaagaggcat
    11641 atgacgatat gacttatgat gatacatctt atgaggaaca accagatagc gctcattctt
    11701 ccaggatcca acgctatcat tgataggcac aaaatacgag agaggctgtg acaaccgtcg
    11761 cagccttttt tggtttattg caattgtcta gcatcttctg taaaatagaa acgttagaga
    11821 aaatcttgta tcatagaaaa ttaagaaaga aataagaacg cagctcggta ccaaaaatat
    11881 ggtaaaatgg cacttgactg taattcactg aaaatcgctt ggaggaacac aaatgtttaa
    11941 agatttgtat ttatttatga aggacattta tcagaacaga aaattattgc tacagttttc
    12001 gatcaatgac ttcaaatcaa gatatgcagg atcgttttta ggaatcttat gggcgtttat
    12061 caatccgcta tttactgtat tgatttattg gctggtattt ggtgttggac tgaaagcaca
    12121 aatgatcgat gcaaaatacc catttatcgt atatttagtt accgggatga ttccctggtt
    12181 cttcttctca gatgcatttg catcaactac ggttgttttt cgggaatata cttatttagt
    12241 aaagaaagtc gtattcaata ttcgtatctt gcccacgacg aaaatcctat ccaatctgta
    12301 cacccactta ttcttcattc tgattggcat agctgtcgcg cttataaatg gtatatatcc
    12361 ttcagcaatg tctttacagc tgatttatta tttattttgc atgtgtgctt tcttgacagg
    12421 attgacttgg ctgacggcat cgatccaacc atttttacct gatatcatgc aattaattac
    12481 gatcgtgctg cagttgatca tgtggacatt accgatatta tggagcccta atcagtttga
    12541 ttcaggtctt gtaagcatat tgaaattaaa tccgctgtac tatgttgttc aaggttatcg
    12601 tgagtcattt ttaagtgaag cttggttctg ggagcatgga acatatactt tgtatttctg
    12661 ggttttcacg ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat tgaaaccaca
    12721 tttttcagat gtgctgtaag gagaatagct atgacagaat atgcaattag actaaaagat
    12781 atcacaaaat cttataatat gtacgcaaaa ccttcggatc gatttcgtga agccctcaat
    12841 ccttttaaga aatcctatca tgatgtattt tatgcgttga aaaacgtgaa tgtagaaata
    12901 aaaaaaggtg agatgatcgg tttcgtggga gaaaacggat cgggaaaatc tacaatgttg
    12961 aaaatcatta cgggagtact gacaccaaca tccggcacga tggaaatcga aggaaaaatc
    13021 tcagctttgc tagaactagg atcaggattc aatcctgagt attctggcta tgaaaatatc
    13081 tatttaaatg gaatggttct aggattttca agagaagaag tcgatgaaat ggtcgatgat
    13141 atcattgaat ttgctgacat cggagaccat atttatcaac ctgtaaaaac ttattcaagc
    13201 gggatgttcg ttcgtctagc ttttgctgta gcaatcaatg tgaatcccga tattttgatt
    13261 gtggatgaag cattggcagt aggcgatctt gaatttcaac taaaatgtat ggaaaaattt
    13321 acagaaatca agaactcggg aaagacgatt ttattcgttt ctcatgatat cagttcgatt
    13381 cgtcgttttt gtgatcgttc ctattggttg aaaaacggag aagtcgtcga atatggcgat
    13441 acgatggaag taacgacgaa ttatgaaaac tttttaaaga aaaaatcagt taaaacagtg
    13501 gatcggaata aaaaccaagt agaacggttc gccgctccag atatcgtcga cgtgacgaaa
    13561 gcggaattgt tggataaaga caaaaatccg gtggatatgc tggaacaagg agaaaaacta
    13621 tacgttaaag taacttatga agtaaaagat gatacaatca aaaatccggt tttaggaatt
    13681 gcgctacgaa cagtcgacaa tttttatgta tgcggactta atactctact agatggtatc
    13741 aagattcctt ggaaaaaagg agagaatatc ttttatctgg agtatgaaaa gttaggtttg
    13801 ttagctggtg aatattattt tgacgttgcg gtctttgaag aaaatgcaac ggttcctttg
    13861 gtatataaga caaagtacat gaacttgttt gtcagcggtt cttatatcgg agaaggcatc
    13921 gtggtcttag accataaatg ggaagaaggg actcatagca atgaaatatg attttgaaat
    13981 ggacctagat gaacaaagca gtgtgggaaa aattgccgca cagatcaaac caggaagtaa
    14041 agttttagag tttggtcccg gaaacggccg attaacgaaa catttaatcg gagcaaaaca
    14101 atgtgaagtg agcattgttg agttagataa ggaattgttc gattttgtca gcgaatttgc
    14161 tcaagatgga ttttatggtg atatcgaaag ttttgagtgg gcaaactatt atgctggaca
    14221 gacatttgat tacgtcttgt ttgcggatgt tttagaacat ttggtagatc ctggaaaaac
    14281 attgaagaaa gtcagagaat ttttgaatga agaaggagag atcctgatta cattccctaa
    14341 cttggcgcat aattctgtca tgatcgattt gttcaataac caattgccgt gggcttctta
    14401 tggtctccta gatgaaaccc ataattcttt ttatactcat gatggcttcc aaaaagtttt
    14461 tgaaaaagcg ggattattca ttaatattga agattatttg tacttagctg taggtgatac
    14521 agaattaaaa tcaacttatg aagaattgcc ggaagctgta cgctatgatt tcaaaatgcg
    14581 accatttggt gaagtctacc aatacttttt ctcattgatg aaacatccag tagcacaaag
    14641 ttccattgca gagccacaaa attctaatta tgtaaaagtg ttagaagtaa cccagcaaac
    14701 gaaacaagat gaaacaatcc aacaaatacc attcaataat ttcacagggg aaaatgagac
    14761 actaagtttc cccgtatcag aaacaacaga aagaatggtg tttcgcttcg cgcaacaacc
    14821 tagctttatc gaattcagcg cagaagctgc cggagaaaaa ctaacattta tcgattcgaa
    14881 tgctgtagtc aaaacagtaa atgattgtta tttgtttgat gggaaagaat taccagagtt
    14941 cgttctaacg gatatttctg ggaaagaagt gactatccat tgtcactatc gctttatcgg
    15001 ggaattgaca ccaacaatga aagaattgtt ggaaacgatt cgtcccatgg ctgaagtcac
    15061 aaagcagctt tctgagaaaa atgacgaatt agaaagagaa aatcatcatc ttcttgagga
    15121 aaatacaaga ctagaccata cgttaaaaac aaccacaaat cgctattgca cattgttgga
    15181 aagtgatgaa tggacaataa aacatagact aggacgacgt aagaaagaaa cttcgaaaaa
    15241 aatccaagaa aaagaacttt ctatatgtat tgacgagaaa atctgggatg cagaaacaaa
    15301 aatattaaaa atcatcggat ggggaatcgc taattcggat cgccagccct tgtcctataa
    15361 gttatcagct gaccaatcgc catttttcga agcaattcct gtttcacgag aagaagtcaa
    15421 tcaagcagaa cagctcgcaa aaggaacaga agcgggattt gagttacgaa tcctttgcga
    15481 gcaagaacgt tcattcttag tggaagcagt agctcaaaat ggccaatcat ggatcattga
    15541 aatgtaaata atgattaact tataaagata aggagtaaac gaatcgtgca aaaaaaagaa
    15601 attgccgtat ttatcgatca aatcactcgt gaacgggcca ctggcgattt gcttattgtg
    15661 ggctgggcaa ttgatgaagt gaccaaagaa atccctacga taaaggtaga aaaagaaaat
    15721 gtgattgctg aagcaacaca tgtcgtaaga ttggatatca atcatttata taatcttgat
    15781 gttaagaccc aaagcggttt taaggtacgt ttatcaggga aaatgagagg aaaagccatc
    15841 ttagacttcc aaacagcgag acatcaaaat ggcatagctg tgaaattaaa cggtaaatac
    15901 ccttatgatg acggcattga atcttcatgg gaaagaaaaa aaagattact gaaaaaaggg
    15961 ataaattatg caaggactca tggcgtaaaa aaagcgatcc gtcgggtcaa attggaattg
    16021 aagccaggat cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc agatttgaaa
    16081 gagcaaagga aagaagcaca aggatttgcg taccgtccat tgatttccat acttatgcct
    16141 gtctataacg ttgaaatcaa atggctcgaa aaatgcattg attcggtact ggatcaaacg
    16201 tatgatcatt gggaactatg tatcagtgat gatgcttcta ctgatccagc tatccgaaag
    16261 tgtctggaat cctatcaagc aaaagatgat agaatcaaag tcgttttccg aaaagaaaat
    16321 ggacacatca gtctggcaac taattctgca ttggaaatag cagaaggaga atttatagca
    16381 ctcttagata atgatgatga attaccgcca tttgcattat atgaagtggc aaaagtgcta
    16441 aacgtacatc cagaactgga tgtgatctac agtgacgaag ataaaatcga tgcagatggc
    16501 aatcgctttg atccgcattt caaagcagac tggtcgcctg atacattgat gggaaataat
    16561 tatatctctc acttaggcgt atatcgaaca agcattgtta aagaacttgg cggtttccgt
    16621 aaaggctatg aaggttctca agattatgat ttggtccttc gtgtgacaga acaaatccct
    16681 gcagatcata tttaccacat tgaccgagtc ttgtatcatt ggcggacgat cccaggatca
    16741 actgcaagta atggcgaagc caaaagttat atctatgatt ccggagtgaa agcattgaca
    16801 gatgccctgt ctagaagaaa catcaaagga agcgtacgtc ctggcagaat ttctggattt
    16861 tatgagattg cttatgacgt cttgcaagag gatttggtca gtgtgatcat tccaacgaag
    16921 aatggctatg aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac gtcttattca
    16981 aattatgaaa tcattattgc ggataacgga agtacagatc caaaaatgca agaattattt
    17041 gcagaataca agcatcagct gaaagaccgc tttatcgtag aattgattga cattccattc
    17101 aattattctc gaattaacaa tttagcagca gaaaaagcaa acggcaaata ctttttattc
    17161 ttgaataacg atacagaagt gattgagcca gattggatga cggtgatggt ttcttatgca
    17221 cagtttgatc gaatcggctg tgtaggagca aaactgtttt atccagatga tacaacgcag
    17281 catgcaggag tattattagg aatcggtggt gttgcagggc atgcattgaa taactatgat
    17341 cgaacacatt gtggttattt cggccgattg gtcattgacg tcaattactt agcagtcact
    17401 gcagcttgta tgatggtcaa ggcagctgac ttcaatgctg ttaacgggtt tgatgaaaca
    17461 ttagaagtag cattcaacga tgttgacttg tgcttgaaag tttatgaact gggtcgttac
    17521 aatgtctatg cacatcaagc agaattgtac catttcgaat ctaaatcaag aggttatgaa
    17581 gatactccag aaaaacaaag acgttttgct ggtgaaatca aaaaaatgca agataaatgg
    17641 ccagcatata ttgcgcatga tccattttac aatgataatt taacaaaaga aggaatcggc
    17701 gacttttcgt tgagaccaga ttaaactata ataaaaagct gttatgttgt gattcgctcg
    17761 cacataacgg ctttttatag ttttttgtca aaaaaaggca gaaggtgccg actcaaaaaa
    17821 ataagtcgag gttgggacag aagtgtttaa ctccgagaaa taagaagaaa ttcacgaaaa
    17881 ttgcttttca aatttttgtg aatttcggct tatttaagaa gaagttgctt ctgctcccac
    17941 cgtttattcg tttttaaaga atgagacaaa agtgtttctt acttttgtcc cacgctctta
    18001 ttcatgctca gagcgccaat agatacaaaa tcatagccaa agtttcacga accctagctg
    18061 tcaaagaatc gatattttat tttaatatag gctattttaa aataaatggt ttaaggtatt
    18121 cctctacaaa agccactcta tcaattatca tgggtttaaa ataagaagtg atggagataa
    18181 ccagattgtt cttagcgtca atataaagaa catttccact attaccaatt gctgaatata
    18241 tttcgttctc agaatctaat acccaccata aatagccata tctcatattt tgtaagtctt
    18301 ctaaagcact ggttctaggt ttgaacatct cgtttatcca catgggtggt acgatttgtt
    18361 ttcctttata catcccttta tttaggcata atacaccaat ttttgccaga tcacttgccg
    18421 ataaacacaa accatatcct gccgtcccga tatttagtgg atcacaaaac cagacattgg
    18481 ttttaggaga cttatccatt gtaaactgct tatgttcttc agctgtttca gcataataat
    18541 tgacatggtt tggtatccct ataggatcaa atagatactt attggcaaaa tcaacagttg
    18601 ttagcttact tgtctgatac aacaagccag ttaatatgtg taaacagaca gtttgatagt
    18661 tgaattcgcc ggttatacct tttcttcctc ccaataaatc tagtgatgtt tttgtccaat
    18721 cttcacttga acagactttt gtccatggat cgcctttaca tttgtagggt gctttcattg
    18781 ttagcaagtg cttgattgta atagcgtaaa tagttttctc cccgcgtttc actttatact
    18841 ctggaaaata atctaatact ttatcatcga tacttttgat taatccttgc tctaaagcaa
    18901 tgccaatcag caaagataca atacttttcg ttgctgacat gatatgacaa gtatcgtctt
    18961 ttttataacc attccattca tctgtataaa cttctacccc atccttatat gcgacaattt
    19021 gacatatatt tggttgtcga aaaccaataa aatcatgcaa ctcttgttta ttcataagat
    19081 attacctcac tttcttctat aagcataatg tcattaaaaa tcgatttcaa ttttttcgat
    19141 tcttcacgta atacaggtat tcttatggac tagacagcgc tttgggaaga tggattctct
    19201 gaaaaatata aaggttcact ttatgagtgg ataaaaaaag cagcaaatac ttcgacttct
    19261 ttaatttacc aacattagtg aaaatcgatt catctggaga tttgtaattt agagtccttg
    19321 tcttgattag aggtgtataa agctttttat tagacatttt taaattccat tacaatttgc
    19381 ttataaacta ggtttttaaa ggtgactatg gtaagataat agagatatta ttttgtgatt
    19441 aggagtgtat atatgaataa aaatggagaa tggagtgctg cacgacggat attcattata
    19501 ttaatggatg ttattgtata caatgcagca atatatagta gtttcttact gaagtttcgt
    19561 ggagagatcc cattacgaaa tttagaaact ttccaacact cagcaattat tatttcagtg
    19621 atttttattg cgttgaacat tttgttgggt gcatatgttt tttataatcg aatgatcagt
    19681 gacatcgtgt ttgtcacagt catcggtcag gtattgatga cactagggat catggtagtg
    19741 acttttgcgg gccgctggtt tgcttttcca cgtcttgtta tcttactttc atttgttctc
    19801 ggtacgcttt tcttaagtat ctatcgtatt ctcgtatata aactttattt acgcgtaagt
    19861 cgagataaaa aggtcgtcat tattgggtta gaaaaggatg tcgcaccagc aatccaaaat
    19921 tttggttcaa agaaaaacaa caaacataaa gtcgaagcag tcattcttga taactattat
    19981 gcaaacatca aaaatatgat taaagacatc gatattgtct atcttgcttc tcatatcgaa
    20041 gaaactgaaa aaatcaaaat ctatcaatta gttactaaaa atgaaaaaaa attgtttttg
    20101 aatacaacat ttgaaaactt gacattgatc aatccaaata ttatgaattt cgaagatgaa
    20161 agtattattg gagcatctgg atttagaatc caacctgaat atgaactatt caaacgtttg
    20221 tttgatatca tcgtttcact tgttttatta gttattgctt caccatttat gttattcaca
    20281 gcaattttag tcaaagtgac atcaccggga ccaatcatct ataaacaagt gcggatcaca
    20341 aaaaatcaaa aggaattttc aatctataaa ttccgctcga tgaccgccac agccgaagca
    20401 aaatctggac cagttttagc taagagcaat gatgcacgag taacgcctgt aggtaaattt
    20461 attcgagctg tccgctttga tgaattacca caaatcttca atgtgctgaa aggcgatatg
    20521 tcgatcgtag gaccacgtcc tgaacgtcct ttcttcgtcg atcagttcaa tgcagaaaac
    20581 ccttattact acttacggca taatgttcgt gctggtatca ctgggtatgc acaagtctat
    20641 ggaaaatatg tctctgatta caacagtaaa ttacgttttg atttacttta tatcaaaaaa
    20701 tattcattga tgcttgattt aaagatcttg ctgcaaacca tcaagatcct atttgataaa
    20761 atgtcctctc aaggacttga agaagacgaa aatgtgatct cattggcaga aattgctttt
    20821 ccgaatgaaa aaatctttcg ctagttggga ggcgtaaaaa tgaacaatcc gaaattcagc
    20881 ataatcgtac cagtatacaa tgcagaagca actattggtc gaacgattga tattctaaaa
    20941 gaattggatt atgaagagta cgaagtcgtt ttagtaaatg atggatcaac agatcaaaca
    21001 caggaaatca ttcaagaact gattgaaaat gatgaacgtt ttgaattgat tactacgacc
    21061 aatcaagggc ccggattagc aagaaacgaa ggaataagac agtcaaaagg agaatatctc
    21121 ttattcttcg atgcagatga cacgccagta aaaacgatct tgtcagatta tgatcatttg
    21181 ctagaaaaga gtccaaaagc ggatcttgtt gttagttcgt ttgtttttcg tacaatggac
    21241 gagggaagaa tcgtttccga aaaagaaaac ttagttacag aatgtcacta tctaactcac
    21301 gaagagttta taaaagacat gtatcagtta atgaatgaac agttgatgta tgttgtatgg
    21361 aacaaatgct atcgtagcga tattctgaaa aataaccaaa ttctatttaa aacttataat
    21421 agttgtgagg atcgaatatt taacttacat tattatgaat actgtcatca agtgatcatg
    21481 aacccaaaag tagaatatat ttatgaattt gaaggtggga aggggatcac taatcaatac
    21541 cgacctaaca agttcgaaac atttaaagaa ttctattcat tagcaaatac tgtaacagac
    21601 gatattaata aagacggtat ggcggcgctt cttttaaaag ggacaacttc agttattttt
    21661 tctatttata gtacctctgc aagaacttca aaagagaaga aagacgaagc aaagcagata
    21721 ttgagtgatc cagtgatccg agaagccaag caaattgcta agacggattc ttcagcaaaa
    21781 aaaataacaa agttgcttta caatatgcca gctccactat ttttatctgc tgtaaaagtt
    21841 ggaagcttcg ttgaagtgaa aatgccaggg ttaatggctg ctttgaagcg agtatattag
    21901 ttaatggagg aaaatataat gaaaagaatt ttgcattttc agggacgaat gggtttaggt
    21961 ggagcagagt ctttcatgat gaatttatat cgtaaaattg atcgtacaaa ctatcaattt
    22021 gattttttga tttatgaaga ttatgcagat gttcaagact atcattcaga gattgaaaga
    22081 ttaggaggcc gtatttttgt tgtacctaat cctaagaaaa atatttttaa atatttaata
    22141 gaagtgaata agttactaaa aaaagaatct ttttctatag ttcacaatca ggtttatttt
    22201 ggcgggggaa ttaatttatg gttagccaaa aagaatggaa tcagacagag aattgctcat
    22261 agccatgcaa ctgaagatgg aaaatctcaa aatattgtaa tgaatgtatt gcgtaaattt
    22321 ttaaccaaat tgttgttaca aaatgcaaca gactaccttg ccgttagtca agaagctggt
    22381 gaaagtctgt ttcaaaacca cccctttgag atagttcata atggtattga tttagagctt
    22441 tatagtaaaa attcagaagc taaggttaat aagagaaaag aattggatat ctcaatgagt
    22501 acttttgttg tgggaaacat tggacgatta gagaaacaaa aaaatcaatc ttatttgtta
    22561 gagatttttt tagaaatact aaaaatgaat tctgattctt acttgatttt agtaggtgaa
    22621 gggtcactta gaaataaact gaaagccaaa gcagtagaat tggatataga gaaaagagta
    22681 aaatttttag gagaaagaaa cgatattccc gagttattat ctgtgatgga tgtttttgta
    22741 atgccttctc tttatgaagg tctgccaatg gttggattag aagcacaagc agcaaaatta
    22801 aaattagtct tagcagatac tatttccaaa gatacaaagt taacaaataa tgtggatttt
    22861 gtatcattag atgaaacacc acaagaatgg gcaaaaaaag taataaaaga gccgtatgct
    22921 aataaaataa cacaagaact aaagagttat gatgtttcgt acactactga acaaatggag
    22981 agtatatata gtagagatca ttaaaaatgt tcaagatatt ttaggagtga ttatttttga
    23041 aaatatgtta tttgatattg gcatacaatg atattggcaa cttaaagaga ttggtcaatc
    23101 gattgaacga aaatgcagtt tttattattc atatagataa aaaaactgat atagaaccat
    23161 ttattgaagc atttaaatca tatgataatg ttgaattttt atgtaataaa aaccgtgtta
    23221 aaatttattg gggtggtttt tccattgtac aagcagaaat caatttagta aagagagcat
    23281 tacaaaatga gaaatattta aaatatgtat tattatctgg tgctgattat ccaatcaaag
    23341 ataatgagta tatttataat tattttaaaa agaatagttc agtggagttt attcgtggaa
    23401 tagatctaga tcaaattaaa cataaagaat tttattataa acatatagat gtatatcaaa
    23461 aac
//
LOCUS       DACBYO010000040        23004 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.040, whole genome shotgun sequence.
ACCESSION   DACBYO010000040 DACBYO010000000
VERSION     DACBYO010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.040"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..343)
                     /locus_tag="IVD26_001499"
     CDS             complement(<1..343)
                     /locus_tag="IVD26_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP6079484.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSN"
     gene            complement(336..1511)
                     /locus_tag="IVD26_001500"
     CDS             complement(336..1511)
                     /locus_tag="IVD26_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP6079485.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(1515..1700)
                     /locus_tag="IVD26_001501"
     CDS             complement(1515..1700)
                     /locus_tag="IVD26_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079486.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(1666..3360)
                     /locus_tag="IVD26_001502"
     CDS             complement(1666..3360)
                     /locus_tag="IVD26_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAP6079487.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(3357..3830)
                     /locus_tag="IVD26_001503"
     CDS             complement(3357..3830)
                     /locus_tag="IVD26_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HAP6079488.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(3899..4054)
                     /locus_tag="IVD26_001504"
     CDS             complement(3899..4054)
                     /locus_tag="IVD26_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HAP6079489.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            complement(4188..4568)
                     /locus_tag="IVD26_001505"
     CDS             complement(4188..4568)
                     /locus_tag="IVD26_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP6079490.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(4572..4787)
                     /locus_tag="IVD26_001506"
     CDS             complement(4572..4787)
                     /locus_tag="IVD26_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079491.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(4790..5197)
                     /locus_tag="IVD26_001507"
     CDS             complement(4790..5197)
                     /locus_tag="IVD26_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HAP6079492.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(5463..6938)
                     /locus_tag="IVD26_001508"
     CDS             complement(5463..6938)
                     /locus_tag="IVD26_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HAP6079493.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(6928..7776)
                     /locus_tag="IVD26_001509"
     CDS             complement(6928..7776)
                     /locus_tag="IVD26_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein"
                     /protein_id="HAP6079494.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(7813..8175)
                     /locus_tag="IVD26_001510"
     CDS             complement(7813..8175)
                     /locus_tag="IVD26_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079495.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(8475..9099)
                     /locus_tag="IVD26_001511"
                     /pseudo
     CDS             complement(8475..9099)
                     /locus_tag="IVD26_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(9096..9407)
                     /locus_tag="IVD26_001512"
     CDS             complement(9096..9407)
                     /locus_tag="IVD26_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079496.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(9451..9744)
                     /locus_tag="IVD26_001513"
     CDS             complement(9451..9744)
                     /locus_tag="IVD26_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079497.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            9938..10585
                     /locus_tag="IVD26_001514"
     CDS             9938..10585
                     /locus_tag="IVD26_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6079498.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            10646..11791
                     /locus_tag="IVD26_001515"
     CDS             10646..11791
                     /locus_tag="IVD26_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6079499.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(11872..12177)
                     /locus_tag="IVD26_001516"
     CDS             complement(11872..12177)
                     /locus_tag="IVD26_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAP6079500.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(12202..12633)
                     /gene="ruvX"
                     /locus_tag="IVD26_001517"
     CDS             complement(12202..12633)
                     /gene="ruvX"
                     /locus_tag="IVD26_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAP6079501.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(12630..12896)
                     /locus_tag="IVD26_001518"
     CDS             complement(12630..12896)
                     /locus_tag="IVD26_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAP6079502.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(13151..13876)
                     /locus_tag="IVD26_001519"
     CDS             complement(13151..13876)
                     /locus_tag="IVD26_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAP6079503.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(14237..14307)
                     /locus_tag="IVD26_001520"
     tRNA            complement(14237..14307)
                     /locus_tag="IVD26_001520"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14273..14275),aa:Gly,seq:ccc)
     gene            14424..15176
                     /locus_tag="IVD26_001521"
     CDS             14424..15176
                     /locus_tag="IVD26_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAP6079504.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            15192..15671
                     /locus_tag="IVD26_001522"
     CDS             15192..15671
                     /locus_tag="IVD26_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAP6079505.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(15922..17502)
                     /locus_tag="IVD26_001523"
     CDS             complement(15922..17502)
                     /locus_tag="IVD26_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAP6079506.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(17495..18238)
                     /locus_tag="IVD26_001524"
     CDS             complement(17495..18238)
                     /locus_tag="IVD26_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079507.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(18414..19190)
                     /locus_tag="IVD26_001525"
     CDS             complement(18414..19190)
                     /locus_tag="IVD26_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6079508.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(19438..20274)
                     /locus_tag="IVD26_001526"
     CDS             complement(19438..20274)
                     /locus_tag="IVD26_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAP6079509.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(20285..21214)
                     /locus_tag="IVD26_001527"
     CDS             complement(20285..21214)
                     /locus_tag="IVD26_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAP6079510.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            21406..21759
                     /locus_tag="IVD26_001528"
     CDS             21406..21759
                     /locus_tag="IVD26_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAP6079511.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(21833..22489)
                     /locus_tag="IVD26_001529"
     CDS             complement(21833..22489)
                     /locus_tag="IVD26_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAP6079512.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            22715..>23004
                     /locus_tag="IVD26_001530"
     CDS             22715..>23004
                     /locus_tag="IVD26_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP6079513.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQ"
BASE COUNT         6826 a         4633 c         3824 g         7721 t
ORIGIN      
        1 catttgaata ggtcgtgtcg gttagctctg cttcaaaatg taatcctgta tcatcgacat
       61 tcaatttcaa cgtacctgct ttgacactag ctagtggctt tgaataatcg tgtccatata
      121 ataagaacac atttgataaa tccacctctt ttaatgcttc gggtgtaatc acttctacaa
      181 agccgcctaa atcttttgac ggttgcccga atttcaacgc atagcctgaa atagttttgc
      241 cgtctgttgg ttgtttttca ttttctttct ctactttggg agaatcggct gttagctcag
      301 cttcttctgt cagccgtttt tccttttctt cttcattatt caactggtgt aactccttcc
      361 tgttctttta attgatattt ctccaacgta tctaaatacg taaagttcaa acttgctagt
      421 aaacgatcgc caccatccat ggggggtagc cccattttcg accgcccctc attaatcgtg
      481 agaagtgacc ctttgacctg atccaataca ttttttactt ttgtttcagg atcagtctct
      541 agtaactgat cggaattaaa gcggatattg gtttcaagtt tcgtatctaa ttcactcaca
      601 aacacattaa agtaatgaat cagcgtactt tggatatact ggagattact ttgaacggtg
      661 ctagaatgtt cattttcaac gcctaaacgc tcaatcggta caccaaacgc cttggcaatt
      721 tgttttgtgt tccaatcatt ggaattgata agcttcaaaa catcggtgtt tatttctaat
      781 gttttgtagt ccattgtttc atcaagaatg atcgttctaa gagcattatc tccactactt
      841 gaaccgttgg cttcttcaaa cttttcacga attgcgttct ttgctgatcc gtctaaatct
      901 gacttatgaa ccttcaaaat acctgaccca ctgacaccac gagtaaagaa attgtgcaat
      961 gtgcggttgc cagcttgttg aattttcagt tcatcacgta acgcataaag tggtggtaat
     1021 cctgttaaac catcttgggt gaaatatttg aagtgcaaaa tatcgctaga cttcacacgt
     1081 ctttttttat caccaatctg ataagacaac gtaccattat ctaattgagt aaccgttaca
     1141 cttgagttag gtaataagtg aatttcttct accttttcac cgttgcgttt aatctctgca
     1201 aagctattac cgtttagcaa catattgacc gccaaagcaa actttaaatg ccaaccatcc
     1261 atttctgaat taggtttctc gtttagtaac ttcaccagtt cattatcagc ttgtggcata
     1321 ttgtttttga ccaattgaat cggacttgaa gcaatatcac tagcaataat tcgaacggct
     1381 gcaaacacat cactatttct taatgcacga acgcttgtaa agctggtggt gtaatcatcc
     1441 gattggattg ataccacatg ttgtaggaaa ggatctcccg ttgtattttg tctcgcttta
     1501 aaaaatgcca tcttttaacc tcccttctgt tctgtattta gcatgaccgc taccccaata
     1561 agcactatgc ccagcgctaa caagccatag tagacatttg ttagtaaggt gatagcaacc
     1621 aacacacaca ccaatccaag aagtaaaaga acggtatgaa tgtaattaga aagaaaattc
     1681 ttcacttgta taaaattcat tgtctgcttt cgctccttcc gttgtggtga agtaatccat
     1741 tgcaaacaca taggcattga ttaatgcagc tattggatca attttgttac tgttctttga
     1801 tttattaatc tgaatgccgt tgttatccgt ttttaaaata gcgttgttca ctgcatgggt
     1861 gagaatcgta tttttattgt gaataacgtt gccttcataa acttgttctc taaaagttcg
     1921 ggtcggaacg tttagagtaa tcgttccttg tcttacttct aacattgggt agttggcttt
     1981 ttcagcttta ctgataagcg aattagcgtt atacgggtca taacaaatcc ccatacattc
     2041 caaatcattt tcttgaatca aatcttgaat aaactgaaat acttggtcat agtccacgat
     2101 tccactttct aattgagtaa tggaacactc accagctttt tctagttctc gataaggcaa
     2161 accgtcgcgc ttttctttgt cttgaagccc atatttggtg gctacaaagc tatgtgaatc
     2221 acaataaagt tcgccgttat ctagcggtac gatccatgaa acgctagtta aatcatctgt
     2281 tttagataaa tccactccga tataaacggg cttgcctgta atatcttgtg gttctacttc
     2341 ggttgcctgc cagtcttcag caatcatata gctgtcctca ctcgcttgtc tccataaatt
     2401 gaagtttttc accaatacag aattaaggtt attttgtttc aaagcaaggt tcacatcatc
     2461 ttgaatggtt ggaatcatta cttttttgat ttcttcactt tcaaaaatcg gattggcttt
     2521 gatccatttc tcttgatcgt gaatttcttc gggatcgtcc aattcccata tcgctataaa
     2581 gtacctgtcg gcttgttctt cgccttttag cacacgatct aacaataagt attcctcgta
     2641 cataggaacg tttaaatcaa gcccagcggt actaataaca cacaataagc cgttcttttg
     2701 ttgggtcatt cctgacttaa tgacgttgta cgttttacga gtttttgctt cgtgccactc
     2761 gtcaagaatt gcggttgttg gtgcaaaccc atctagcgtg ctggtttcac tagccagtgc
     2821 catagcgaac gaattagagg gcaagtgctg aatcttagag ttcataattt tcagttgtgg
     2881 tcttaaaaac ttactagact tgaccacgtt tctaagtgaa ttagacagca tatcatagcc
     2941 caatttagct tgtttcaaag cgttacttac aaacaatact tgccttgctt ctgctggttc
     3001 ttgttccata atcaacgcat tggcagccat gccacttgcg atatacgttt tcccattctt
     3061 acggctcata ctggtaaacg ctcgattgaa tcgcctgtaa ttcccttctt tagtacgcca
     3121 gccataaaga ctgcctagaa tgaatttttg aaatcctaac atcttgattg ctttaccgtc
     3181 cgtagatggt agcaactcaa tgaatttaat cgctttggtg gcttgttctt catcgaacac
     3241 ataagggaag ctatctgact tagaacgctc caaatcgctt atatgacgct cacacgcttg
     3301 gataattttc ttgggtgcaa tcagcttacc tgataggact ttctcaatgt aatcattcat
     3361 gaattcatca actctttgaa cgggtcttcg ggttcatcat ttttaacctt gttcaaagct
     3421 agttttgatc gtgattctaa ggtcatacct agtgaggtgg cttgtttttt caaatcactc
     3481 atagcttgtg attgaacccg aaccgctgga ttggctttct ttactccgtt ttcgcatgtg
     3541 ataaacgtac ctgattttct tatctcggct tcggctgttt tcattcgagc aaaggctaaa
     3601 caataggcta ccaatgaacc ataatctgct tcactcaatg gataatcttt ttttaatgtt
     3661 ggtacgatac gattccattc acttctagcg ctcgctgcca tccagtcagg gggcgtgata
     3721 tttattaatg gttgctgctt gaacaattct tctctagcgt ccacacggat tgctttttct
     3781 tcacttgata tattgccttt tgtatcgtgt aatattttag ggtgtcccat gttgtcctcc
     3841 tttcagacaa aagaaaaagg aacgtaagca attaagctca cattccttcg tttttcgatc
     3901 agaatttttc tttatctaat ttatctatat aaatgatttt tccgttctgc atttgaatgg
     3961 tcacttgacc aaaatgaggt aactcaatgg tgcgctgttt ccctgtttta tcagtaataa
     4021 caattgtatt tttcaataaa tctcctactt tcattatata ctttttcact tgtgattaca
     4081 agtgtaatcg ttatttgtaa ttacccttat gccttttcac aacggttatt tgtaccaaaa
     4141 tgagtaggca tcgattgtca gtaagtttca cactatgccc ccttaactca aagggtactc
     4201 ttttctcgtc tttgtctttc attggctgtc ttggaattat ggtgtgcatg gcataaagaa
     4261 cgaaaattag tttcatctaa ccgtctattc caatcatctt ttagttcaat tttgtgatct
     4321 acaacatcag ctttccttat caagccttct tctaggcaat cctcacatac tggatgattt
     4381 aaccgataca agtatgaagc ctttcgccat gttctacttt gatagaattg aaaatattta
     4441 ccttcgcttt gctttctttc ttcacgctta attgccgttt gctttgcttt atgcttccca
     4501 caatacttct gcctataatc aatcaatgtt ttacatccag catgattaca ttgtttttta
     4561 actgccatag attaccaacc aaagcgatct cgttcgtcag aatcatcttg ttcccatttt
     4621 gatttgtatt caatataagg cgaaactatc ttcaagcacg ttccgtcttt aaaattaact
     4681 ttagtgattt tatcttcctc aaaactaata aagtctacat cttcttgagt gtttgaatac
     4741 tcaatgtgtt tctcaccatc gaagtatcta atactttcca tatgcataat tattctacct
     4801 ccaataaatt agttatcaat tcatcatctg ttagtagcaa agccaagaac ttatcatgga
     4861 tgtttaaaaa caaattatcc tcattcgatg taagctctcg ttgtctcgct cgatcatata
     4921 ggttaagcag acaattaaat tcatccatta gctcacctgt atcatcatag ttgccactat
     4981 ctaccaatga tcccactact agcgattgac accacgctac tgactcctgc agccaatcag
     5041 gttcttcttc cattatcttt aatacttctg gatcaaatgt ggaataatct tctgttacca
     5101 atcccacact aaatgccagc gtgttcatta gaaaccgatc catttcatct gtatattgaa
     5161 agttcggtgc tttgtttgtt gaaataatat tgagcattta ctttcctcct tgattcgtaa
     5221 cacgtggtaa cacctacgta acaggtaccc gttaccactc aatcccaacg gggacaaggg
     5281 ttctagcgtt ttggtaacag gtaacgggta aaatccagta acattattcc ccagcatatt
     5341 agctaactat ttcaaaagtt ttaaggaaat aaggtgttac cccgttacca aattgctgta
     5401 tcccttgggg cagtaagggt aaactagtaa cgggctaggt gttactgacc cgttactacc
     5461 cgttactttt tgtactttcc agctcgattt ttattttcat aggcatttga cttattgtaa
     5521 aatcctcgtc gtttatttct ttttggcagt tgcttccgtt cccaaccagg aatactgcta
     5581 ataatcaagg caatcttttt agtttctgca tctgatcgac cattcaataa atcctttgct
     5641 tgtttatcaa aaacagcttc caaaatatca gcggtgagta cgctatcaac taaataaaac
     5701 tcttgttgca tagtagctcc attatagaaa tgctgtaaat ttttctcatt acatttactg
     5761 tcaggatagt tctgataata agaacgtctc gcccacgctg gagcttcttc ccatttatac
     5821 gggatttcca tttccaaata tttagtgatt gcttctttaa ttggattctc catcttggca
     5881 tcctcttgat agtcttttgc aatttctaag acttctttat cttcatcggg actaaaatag
     5941 attcgttgtc ctttatcaaa aagcaccttt gcttcagcta acacttgaag aaaatattca
     6001 tcctttgttt taaacggatt catctttggc ttattcttac aaggcaaagg ataaaaacgg
     6061 cggtttcctg tatcatcttt caaatactgc ccatcattcg acgttccaat aaatacacat
     6121 tgccttgccc aagctatgac attccgacca taaggaggtc taattttatc gatcttggca
     6181 ctgatgaagt tttttatctg ttcaatttta gttttgttca ttgaagataa ttctccaagt
     6241 tcaataatta cattgccttg aagctgcata taatcatctt tcttttcacc tagcgaatct
     6301 aatgaatcgg tgaaaaaatc atccgtgtaa agtaatgctg gaacggtact cttaccaatc
     6361 ccttgcggtc catccaaaac tggaacgatc tcaaacttta ttcctggttt atagatacgt
     6421 gcgactgatc cgactatcca acgttttgtt acttctcgtg tgtaaaggtt gtcgtctacc
     6481 cctaaaaggt caataaacag tgtttccagt ctaggctgtt gatcccattt aactttttcg
     6541 atacgttctt ttactgggtt gaaaacattc tttctagcca catttactac tgctttgtgt
     6601 attttgttgt catcaaaaac tacattgtag ttttcttcaa tatatgccgt taaggcatcc
     6661 tcaaaactgt cttcccattc tccagcggta cgattgatcc aaggagaatc ttttaatagg
     6721 tgaatgtatc cgctaaattc gttataagca attgttccag ctaaattgct atcattggtt
     6781 aaaatcaatt ctgcattcac aacactgtta cttttaatct gatcgtcttt attgcatctt
     6841 aatcgtgaca tccaggtttt caattcaatg atattgtctt cacgctcgct ggcttcggga
     6901 aagtctaaaa tactatctaa tttatgctta tgagccatga gctttccccc tcaaatcttt
     6961 tttaatcatc gatcgaataa tttgattcac ttctttatct tttagcggtg gttcattgta
     7021 cgcatttgct gtataaatca attctgctaa agtttgatta tctacaccgt gccatagtaa
     7081 ccaaccgcat aacttagtta aatgatcgtt tctactacct tcgccagcgc cttgaacaat
     7141 catatctaat ttttttgctg tccctgtttt tgctacgggt cggtattgag tctttatttc
     7201 ttgcggtttt tttagcagta ggttcactag ccaatcggga gctggtgcaa tattatttag
     7261 agatacgttt tcaataggtt catatgctct cccaacactt cttgaaataa tcatagttgg
     7321 cgctattgga actcctttag tgataatatc aatcccgctt aaacttttac ctttatcatc
     7381 acgcccgaag atatcagcaa atgcacctgt ttcttgttgg ataattacac catcaggaat
     7441 tttaaagaag aaatggattc ctttacctgg tgtgatttcc gtataagtag aaggaaatgg
     7501 atcatacatt gaagcaagtt ttttataatt ctcaacgccg tttcgtgttt cagaatgttg
     7561 atctaggtca actaccacca tttgatgatc ttcaagcatt aacccaatat ttctagttgc
     7621 atcttccgtc caccattcat taatttgatt agaatcgtta gttgcatcat tccaaccact
     7681 agagcctttt attggaattt tagttccagg agataaggga taaattgacc atcccgactt
     7741 ttgtaattcc gttgctgctt gataattatt tgccaataaa cctctcctcc tttttcaaaa
     7801 tactggtata aatcattcag acacctccat gagcttcaac tgctcaagtt cgtatttcaa
     7861 cccatcccga acaaattcag caccttttaa ttgattctga tactttaccc atgtattaaa
     7921 tgttttcacc cttgcttctt gcatatcagt aatgtttaac catgcggtta aaatctgatt
     7981 ttttagctcg ttgatttctc gacaaattat tttgtgttct gcatgttttt tgagtacata
     8041 caaaactgtt agtttttcat tgaatgaatt tccaaagtag gttttcccga tattattttc
     8101 tagttcagcg atcccttgat taatttcctc taattcaagg ctatcgagtt ggtttaatag
     8161 ttttgttttg tacatctact tatgccctcc agttcttaat tgatagtcgt actcgtcata
     8221 agcagtgaag agatataacg ctaatcctgc aaagatagct atttttgcaa ttaatggtaa
     8281 taagccgaaa attccgccga ttaaaatgct tcctataatt aagtttcgtt tcataatggt
     8341 tccctccgat tttttaatat ggtataatcg gaacaaagaa tatcgggttt tatcccaatt
     8401 aagttgcctt tatcctgtcc gccaagactg ttatggataa ggctttttct ttgttctcga
     8461 tcatgttaat gctcctaagt tgtctgcaat tcagcagaac gattataaat tttctcactc
     8521 actgaaaact gcaacccata tttttcttta acagtcatta attctactgt ctcatctaaa
     8581 ataggttcac gatcaaccaa catttcagga gtcatatctt tcttttttac cattttggaa
     8641 tgaccataaa tagttgatac agctttattg gctatcacat tcgctttaat gtagtctact
     8701 ggttttggtt cagtaatagc gtggcttaat ttagtcattg cttctttttg gtgttctttg
     8761 tctagcatgc ggaatacttg aaagccttca agtcctgtgg actggcgtag ttctttgatg
     8821 atgtcgaaaa tccagtcttg aaatgcctcg gcttcttttt tacggctttt gaatgccatg
     8881 cggtaaatat tttttttcgt tgatgatgtt tacatcttgt gttctgccca atgaatcgat
     8941 gaccttacta gtagtaaccc catctttagg caaagagtga atggctctag taacctgttt
     9001 aagacctaac gcttccgcaa catctttcgc cactgcccac cattcatcat taatatcgac
     9061 aaatcttata atgtgtccgt tccaaatttc agttttcatt caacgtcctc cagttcaagc
     9121 cctagcaagc tcgctaacaa ctcaacttgc tgatacaaaa tttcttgata ctcttcaata
     9181 gaaagtcgtt ctttaaactc tgcttgtact aaatcgttca agccacgcaa tactccgctt
     9241 accgttggtt cttgtggtag caatttttga tagtccattt gttcgtacaa acattcaaac
     9301 gtttcttcta gcgctttgcc ttccaagttt gctaattctg ccgctgtgtc ttctgtaaga
     9361 attgttgata atactttttc gattgcttta ttttgtgtcg attccattat tatttcctcc
     9421 tattaatccc tttgccccca cggcttgcgt ttatttttgg tattcttcca taaagcgatc
     9481 acattcatct tgtgaaattc ttacgactcc atcaactata atcaacttta aaccgttagg
     9541 aacatatttc tgcatcatag tattgtatga aacgttcata tacttagcag cttgtgcctt
     9601 gttcatatat tttggaaact ggtacttttt ttctaataat gaaagtaacg ttccttgagt
     9661 ttgctctact tgttgaacaa ctcgatcgtc aataatttta aaagctggat catcaagcgt
     9721 gagtttgtca atttttaatt ccatatttat cccccctcgt tagcatacat ttctatacaa
     9781 agattttaaa aaaatgcaag aggctcttga atacatttct atacctctta taaactcaat
     9841 ataccatcat accttttcat ttgcaagaat tttaacatac ttttttgaac ttttatgttt
     9901 cacacatatt taaatcgtga tatagtagag aaaatatatg aatggtggtg aaaatgtggc
     9961 tagaaaaaaa taccccgaag cagtggagac aggacaaaga attagactgg ctagaattga
    10021 aaagggactc tcaatggaac aacttggagg taaattatcc ccaccggcca gtaaaggtgc
    10081 cgttagtaat tgggaaaatg gctataatct tcccaataac accaggctta aacaactttc
    10141 aaaggtatta gatgtatcca ctacctatct attaaacgga tcttatacat taagagatat
    10201 gcatatgatg cccgaaatta agcgaaatgt gcttgaaaag caattgaaaa aaactattga
    10261 aaaaaataac tctataattg attctaatct ttctaatgct atcaataaca tcgaagaaga
    10321 taacctgact gtctcacaga agatttattt aacaaacgca ataaaatatc ttaaaacagg
    10381 atctcgaatt gaatttcctg acgggagtac cccaattgct tatctcgcag ctcttctaaa
    10441 tacgctttta cgatatgact cattaattaa tgattcagaa aaaaatacag atgagaaaaa
    10501 agagtatcaa gaattttatg aaaatgatct tctaaaagag ttcacagctc ttgttactga
    10561 gctaaataaa cactattcaa aataataata aactgcctcc tccaaccgcc cccacggctt
    10621 gctacactat ggagggaaaa ctattatggc aacattcaag caatatgaaa ctaaaaaagg
    10681 taaattttgg ctctatgaag cctatcttgg aatgaacaaa atgactggca aacctgataa
    10741 ggttcgtaga cgaggttaca aaacaaaaaa agaagcccag cttgccttgt cacgcttgca
    10801 agtggactac gataaaaacg gtattaaaaa agcgaacaac gaaacgttta aagaagttta
    10861 tgacttgtgg ctagaaacat ataaaaccac tgtccgagaa gccaccttca tgaaaactga
    10921 aatcaagttt agaaagtgga ttcttccaaa atatggaaat cttcgtgtga atgaagtcac
    10981 ggtaaaaaaa gcccaacaaa ttgtaaatag ctgggctgaa actactgacc aatacaaggt
    11041 acttcattca acttctaagc gtatttttag ctacgctatc aatcttggga ttattgagac
    11101 taatccacta gacaacgtat taatgcctaa aagaaccacc actaagcata aagaaaaggt
    11161 caaagtttac agtaaagaac aactgatcac cttgtttgat tacctaaaca gcaaacctga
    11221 aacttatcga aacgactttg ataaaacgtt actacgcttt ctcttttata gcggggttag
    11281 gatcagtgaa gcccttgcat tgaattggtc agacattgat tttcaagaaa atacggtcac
    11341 catcaataaa acactaagcc aatccaaaaa tggctataaa atcagtgatc ctaaaactga
    11401 ttgtagtgct ggggttcttc cactagatga aagaacaatt tctatattaa aaaaatggca
    11461 gattaatcag cggaaatata tgctgacact tggtgtaact gatccgacta tgattttttg
    11521 tggtatctat aaagaactaa tcacacacca cgctatttat gcaagattga ttactatttg
    11581 tgaaaaagct atggttccat ttctcggtgt gcatgtagca agacacactc atgcttcaat
    11641 gctcttggac gctggagcta ctatggtaga agttcaaact agattacggc atacaaaaat
    11701 tagtcagacg atcgattgtt acggtcactt ggcaaaagaa acgaaagaaa agactgttga
    11761 aaaattagta caacacttaa atattgacta gatggcatac aatatggcat acagtaaaaa
    11821 ataaaaaaag gagaaaccct atcatatcaa ggtttctcct agctttatag tctattcttc
    11881 ttcttccgcc atgaatgtat tgaatacttc ttcaatcatg tcccattctg cgtctgtttc
    11941 gatttgttct aactcgcctt ctgttccatc ttcgttttcg atgtatgcat aagcttgtaa
    12001 ttctacatct tcatcttctg aaacaccagc aggatataaa agaacatagt tacgtccaaa
    12061 ttcttcttgt ccgtcaactg ttagtaggat ttcatataat gtttcatttc cttggtcatc
    12121 caccaatgtg atgtgttcgt gtccttcatg gtcgtgggaa tggttatgtt ctgtcataag
    12181 attacctctt ttcttttatt attaaaataa ttgcttacct gagccgtcta aataattttg
    12241 taagatcatc acagctgcta atttatcgat gacttttttt cgtttggctc ttgaagtatt
    12301 tgcctgctct actagcatac gttctgcctg aacagtggtt aatcgttcat cttgataatc
    12361 aactggcaag gagaatagtt ctttgatctt ttctccgtat gacatggaag cttctgccct
    12421 tggtccgatg gaattgttca tatttttagg taatccaact acaaaccggt ctacttcata
    12481 ttgtgctact aattccttca accgatcaaa gccaaactct tcttctgctt cattgatccg
    12541 aatgatctct actccttgag ctgtccagcc aaaggggtca ctgatagcaa cacctactgt
    12601 cttagaaccg acatccaagc ccattactct cataaattca ctccatgatt tgagaggtag
    12661 tccttgacaa ttacttccat gatctcatcg cgttcgtgac ggcgaatcaa atttcgagca
    12721 tcacgataac gaggaatgta ggacgggtct ccagaaagca agtagccgac aatctgattg
    12781 attggattgt agcctttttc ttccaaagcc cgataaacaa tcgctaatgt ttcgctcact
    12841 tcttttttgc gactatcgtc aaaaccaaaa cgtacggttt catctgtaaa acccatgatt
    12901 ctacacctct ttcccgcaag gtaattccag cttaccttct acaaccttat tttactcgaa
    12961 gaaagggaaa actacaaaca aatattccaa acttccgaat aaattaagaa acactatttg
    13021 tatgtttttt tccttttttc tgtagcttta tcaaaagtac tcttttcata aagtatacgc
    13081 tatatttctt tgaatgtatg tttttacaca attttttcat aatattcata aaaaattcga
    13141 atagctgcta ctaatttttt gtttttgttg cttgtcctgt ctcataattg atcgtgtagc
    13201 catcttgaac attgtagata aagacattga attcaatttt tttgtcttca atgctttctg
    13261 cttccaattg cactcccctg gctaccagtt cattcccctc aaaatgagga gtgacacggt
    13321 agcgtacatg atgatttgtt tctttgatat atgccgcaat atcattttcg tgagcaagca
    13381 tgtatggagc attcaacgaa cgtgtccctg tcatcaagtt tttaatgttg ttattttgac
    13441 cagtcagctg gaaaccaatt aaatggctgc gattatataa ccattgcccg tcacttaatt
    13501 tcttttgttt ccaacctgtc gggtcaatat acaaaggctc tctcttttca gtagggaaca
    13561 aatcttttcc aagcatagca ttggcttgtc ctactctgtt caatttatca atatttgaat
    13621 agctttccca tgttcctttg gaaaggctaa gatcctcttt tgtaaattcc ggctgattcc
    13681 cattgatttc tatttcttga tgttttccat catattctgg cacatccgct acttgagaag
    13741 cttgtggtgt ggaatcaaaa atagttgtaa tctgctgaaa gatatctgaa tctttttgtg
    13801 tggtggaaac accgaatgcc cctgcaatca cagcagcgac gatccccacg atcgccttgg
    13861 ttgttttttt gctcatttct ttactccttt actaacagct ccctaaatct taacatatgt
    13921 tcccctataa ataaatacta gaaagaaata gaaacagcaa aaaataaaac ctgttttaag
    13981 atggcttaaa aatacaaaaa agagacggat tcctcgtctc taatcagtca ccactctatc
    14041 tgtaaggtat ttattattat tcaaaaattt tcttcatact caagacaata cactgatttc
    14101 acaaccgctt ggtaaacggt gcgcaaaagc ttgcatctgc ggtaataagt ccatccaagt
    14161 taaaaacata agaagttgtt tttgcttggc tgttcttatt acttgttgca gagcagcttt
    14221 ttcacaacct attttaagcg ggtgacggga atcgaacccg cgacatcagc ttgggaagct
    14281 gggattttac cactaaacta cacccgcaat acaaaaacag tatacgcctc ttttattcct
    14341 tcctcaagtt tttttattct ttacgcttct ggtatgtttt gtagtaaaat aaaactaatc
    14401 aatcaattat tggagaagat gctatgacgg gaaaagaatt agatctgttg ctggacactt
    14461 gtttactcgc tgggaaaatc atgatggaaa gcaatgcgga gatgtatcgg gtagaagata
    14521 cgatgagtcg aattgcttta gcttctggaa atttccgttt ggtcagctat gtcactcaaa
    14581 ccggtctctt tattggtctt gatcgtacct cgaccatccg aatggaacaa attaccaacc
    14641 gttcgattaa tttagaaaaa gtagtaaaag taaatgatct ttcacgtaaa tatgttgctt
    14701 cagagctaac attagaagaa ctttactgcg aactgcaagc aatcgaccga gaccgttctt
    14761 tctttcctgt ctggttgcaa atcgttagcg cggcagtgat cagtggaaca attatggtgt
    14821 tatttggcgg aaagatgacc gatttacctg tgactttagt cattggagga ttgggatacg
    14881 cagcttatct atatagtttg aaatttttta gaatcaaatt tttatcggaa tttttatctt
    14941 ctttattgat tggcatagcc gctatctaca gcgtacgttt tggcttagga agcaatcagg
    15001 atctaatcat tatcggatgt gtgatgcctt tagttcctgg agttcaaatt acgaacgcta
    15061 tccgtgattt gctagctgga cattatgtct caggagtttc tcgcggaaca gaagcgatga
    15121 tgactgctac gatgatcggt tttgcgattg cttttatttt ccagcttttt tattaggaaa
    15181 ggaacacaag tatggggacg atatttattc agttttcttt tagtttttta gcgactgcgg
    15241 catttgccgt tattacaaat gtacctaggc gttcattgat ttgttgtggt ctttctggtg
    15301 cttttggctg gatgatctac tggatctgtg ttcaaatagg cggatctgct gcttttggtt
    15361 cattgcttgg ttctttagga gtagcattca tcagcgatct tttctctaaa cgtttgaaaa
    15421 tgcccgtaac gattttcaat attcccggga tggttcctct agtccctggt ggtttagctt
    15481 atcaagcggt tcgaaatctc gttactgaat cctatcgaga agcggctcat tatgcggtcc
    15541 aagcaattat gattgctgga gcaatcgctt taggtcttgt attatcagaa gtctttaacc
    15601 ataacatccg taatttcaaa gtaaagcgtg acgcaatcat gatgaaacga aaaaaacggc
    15661 tttttaaata aacgaagtgt aacaaagaaa aggttgtgaa agagacgttc agccttgagc
    15721 gatgacaaaa tatctcacaa acattgcgac aagtaaccgc aggagcaata agaagtaatt
    15781 atgagtatta aaaaaagttt tgtaaaaata gcttctcaca tttttacata aaattgactt
    15841 aatactgaga aactgacttt tgaacaccct ctatctgtaa aaaaggggct gcgacatgat
    15901 ttttgtcacg gcccctcttc tttattcaaa ttttttccaa aacgttcgtt gataataaac
    15961 gatccataga gcggaaagta ttagaactaa accgatcaca ggaatattca ctaaccaaaa
    16021 tggataaaac aaagccaaca ttccgtataa gacgataaga ataatactga tgatcaatga
    16081 acccatcata gttgcgacta aacccaaact tcctgaacct ctgttaaata attggttaat
    16141 attggtccag ttcagcagca gcaaccgata atctctagcg aaataacgta gtgacaataa
    16201 gtagcagccg aataaagaac caaatagcaa gctagggata aaaaacaaag gcagctgaaa
    16261 agacagtccg cttaataatg cgatcccacc agttaaaaaa ctctgcaata tccatccgaa
    16321 tctgaacttt tcttttaaat attggttcat agagattggc aaagaacgga taaacagaaa
    16381 attttcttga tccaaagaaa taagattgct gataaaagaa gtctgattaa ctgttaagaa
    16441 agccaatgcg atccctacca ggaaaacaac accgattaac ttattatcta aatcagttaa
    16501 ttttatttcg cctcctaggg caaaagcaag aataaaaatg attggagtta acaaggaaga
    16561 agaaagaact tgcataatca aattaggttc ttttactaat tgagcattgt aactaaataa
    16621 aagctgatgc acattttggt tctttttatg ggttcttttt attttgaact cactgtttga
    16681 atcagtcagt tgctctgtaa gctttggtac tatcagctgt tttacagcaa ggaaaaatcc
    16741 cagagccgtg atagctagta ttccccaacc caataaacct tgttgagaaa gtggctgact
    16801 ggcagcatca tagaatggca ataatatcga aatcggatgc cgatctgtta actcattttc
    16861 aatagtcccc gtttgatgat tcatccacat gattccagca aatgcgatca gcatcgagct
    16921 gccaagcaag atactagaaa ctgtttttct atgtttttta aacactgctg ttcgagccaa
    16981 accaaaaaca atcaaactag ccagacaaaa aagaataatc aaaaatagag aaaacaaaag
    17041 gattgagata atgatagtaa gcaaaatccc tagatcagct cgccatccgg ttaaaataaa
    17101 catgactaga agcggaaaaa caaaaggaat gatggtcaaa gcaactacca aaatctttgc
    17161 tgaaaaaacc tgttcttgtc caaaaggcag aggcaaaaat acttgcaggt catttccttc
    17221 aaaaaagata ttataaatga ctgatatact ttgagttaaa cctaacatac caaaaagtgc
    17281 cacgtaataa gtaaagaaac ctggcaattt aacaaagttc atagcaaaca tagcaaatcc
    17341 gtaaatcagt aaaaaaatca gccctgaaaa aagattttga gacaaaagat agatagttaa
    17401 tcgctttccc ttttttcctt tctctcttgc tttattcgtg agctgtggat taacatataa
    17461 aagattaact cgaattaatt ctaataattg tcgcttatac atacggtcca tctcctgtcg
    17521 cttgccttcc agccattttc aaataaatct tttctagcgt ttcatcaggt gagccattca
    17581 ataattcact aactgccccc tgataaatca attcaccttt cttcaaaata gccagtttat
    17641 cgcataactg ttgtgcggta tccaatacat gtgtagaaaa aatgactgtt tttccttttg
    17701 cggcatgagc cttcatcatt tctttcaaat caaatgctgc ttgaggatca agtccttgca
    17761 aaggttcatc caatacccaa atatctggat ctggcagcaa cgtgccgatc aaaatcgttt
    17821 tttgacgcat tccatgtgaa aaacttgcga ttgtttcatt ttgatgacta tacatatcaa
    17881 aaagcgctgt caattctgct aaacgctttt cttttttttg tgtgtctaat tcataggcag
    17941 ctgaaatcaa gtcccaatat tctccagccg tcaattgtaa aaaaatatct ggggaatcag
    18001 gcacataacc gattttttgt ttgatactca atcgattttc cgtcaatttc attccatcta
    18061 ctaaaatcgt tcccgatgat ggttcaataa tactaactaa acttttaatc gtagttgatt
    18121 ttccggcacc attatgtcct aaaaatccaa aaatttcccc ttgtcttatc gagagagaca
    18181 agtcttttaa tgcttgtttt ttcccgtaac ttttacttac attgatgaat tcaatcattt
    18241 ctgtactcct tttgtttgtt attacttttt attgtaccct tcgttattgg tggagtaaat
    18301 gtcaaaaaga gtgcataaca aaaaaggata gaaacgacta ggctgctact tgggttgttc
    18361 tcttctacag gaaaacactc ttctaacagg taagatatga gtctttgttt tctttaaaat
    18421 gattcatttt ctatcttttc ttgcataaaa ttctttagtt tatcaatact tctctttccc
    18481 atctctagtt gttctccatt tgcaaatgtt actatttcgt ttactctgct aatagatgta
    18541 atgttttcag tattaatgat ataagctttt aaatctttac ataaatactc atattcgagt
    18601 gattttttat attttttaat tgtgccgttt acgagaatct cttcatcttt caatactagg
    18661 cctattttat ttttataacc tggcatgctc attagataaa ggatttcatc gtaatggata
    18721 tagtgatcgc tattaccata acggacagtt gtccaccttt ttttcgtagc atgttgaaca
    18781 ggatagtttt ctttttcttt caataagtaa ctttggatgc tttttttatt tttttcataa
    18841 gtgaattctt ttatcaaata accactaggc gtaatctttc gattaataac agttattgct
    18901 ttattcggat gagacgttag ataaacaatt ttacactttt cattcttttc tctaagcatt
    18961 tcgcctagtt cgataccgct ataataggcg ttcaaatcga tgtctaggaa aaaaatatct
    19021 gaggaataga tttcattatt tttaatgaat tcaacaaatt gtataacgtt caatccctga
    19081 acgatctcaa atttccaagg acttaataaa attctggatt cttccaaaat ttctactagc
    19141 attttttcaa aaaccaaact atcatccaaa ataaatatac gcgttaccat aaaaagtacc
    19201 tccactcgat attttactat caaaatcatt tcatacaact tttcaacata catgttagga
    19261 ataaattgta attctcttca caatcttttc caacaccttt gaaaccgata tcaaatactt
    19321 tcaggatgct gcttctaaaa taaatatcaa acaaatgaat acatcatgca aaaaaagcca
    19381 gacaaccgac gtccttgcgt gtcagctgtc tgagctatgt ttatttattt tgttctttta
    19441 aaaagaacga tacacatact gatttttcgg agcagagact ttctcagcgt ttgtaacaac
    19501 tacagatggg atttcacgct tgaatggttg ataatagtct gattggatgg ttccttctat
    19561 tttataccat tcatcatttt taaccgttac tccttccggc atatgcgtca acaaaccaaa
    19621 gactcctgaa tctgccacac aatggataat gccgaatcgg aacaagaaga tatctgtatt
    19681 gctatcgttc ggtgtttggt aaacaaatcc ttcatagctg atttttttgc caatgaattc
    19741 gctagggtaa ttataaatta gctccataac ttctaaatag ttttcatctg tgatcttgat
    19801 agtttgctta tccccatact tttctttcaa ctcattcatt tggtctaagt agtctgattt
    19861 gttgaaataa atactggtat ccggctttaa gtattgtgtc tgcatctccg gatcccctac
    19921 tgattcttta cttactggga aattaaatcc tttggcttct acgatcgtag tgtcgagact
    19981 aactgttgga aacaacgtcc ccacgattac tggcaaagct agcagtacat aagcgattcc
    20041 acgttgataa ggttttgaca acccatggtc atgatcgtgc tcgtgtgcct tttcttctgc
    20101 ttttccgttt ttgacccaca aatacagctg aactaaagcc aaaagagcag ataaaatcat
    20161 tgaaagaata gctaagtagc gataatggac attgatatat tgatcgagtt tgccagaaac
    20221 ttgcaagtac atcatcaatt cgaaataccc agataaaatc aaaaaccgca gcatattttc
    20281 cctcctaaat aaataatgtg aatccaataa cgctaagggc aatcagtccg atcagcgata
    20341 aaataaagcg tcctgtaaaa tatcgtttca tcatcagtag atttttgata tcgaccattg
    20401 ggccaaagac caaaaaggca gctacaggtg ctgtgccgaa cagacttaac aaagaagatc
    20461 ctataaacgc atctgcttct gagcaaagag acatcgtaaa ggccaataac agcatgatga
    20521 taatggctaa aatctttgtt gagccgagcg ttagcataat tctagttggt aaataagtct
    20581 gcatcgcagc tgcgattaat ccgccaatga tcaaataacg acctgtatca aaaaattcgt
    20641 cgattgaatg tgtcaacaca tgcccagttt gatggatcag ctgatttttt ggttcattct
    20701 tctcactttg ttcttcttca tggacatgat gatggtgatt ttctgctact ttagacgtga
    20761 ttttttcttt caatacagcg tctttttgaa aataggcaag ccagacacca atcacaaggg
    20821 caacaaaaaa gctgcctatc acccgccagc ttgccatctg ccaagaattg ccaaatgcga
    20881 taaaagtgga aaaaatcacg attggattga tgatcggagc agtcagcata aaagcaaacg
    20941 ctgtgtgaac tggtacgcct tttttaacaa attgatgaac gatcggtacg atgccgcatt
    21001 cacatgaagg aaagaaaaat cctaagatcg aaccagtaaa aatagagaag atacgatttt
    21061 caggaagcca tctcttcaca cgttctgggg tcaaaaatac ttgtaaggcg cctgagataa
    21121 gacagcctaa taatacgaaa ggtaatgctt caataacgat cgataagaaa atcgtactca
    21181 tctgcaaaac cgaatttgga ataaaagaaa acatgagttt cctccttttt atttctagtt
    21241 cattcgcttt gcaaatatac gcttttattc aaaaaaaaca agttgctctg taaattttta
    21301 cacaactctt attttttacc aaagcacttc aattgacttt ttctgttatt cccattaaat
    21361 taaggtctca tacatatcac ttctatcata aaagggagaa taaaaatgaa acaaaccact
    21421 aacttgactg aagttcaaga catactgcaa cagtcatccg ttgccgtcat ttatctttcg
    21481 atgcctaatt gcagtgtttg tcacgctgtt cgtccacgac tagaggaact tctcacacat
    21541 tatgatattc cggcacttca tttggatgca tttgaaacac cagaagtagc tagtaaattt
    21601 gaagtgctga ctgcgccagt tgtcctgatt tttcatcaag gaaaagaagt ctttcggcaa
    21661 gcacggttca tcgactttaa aaaaatccgt tatctactag atgaactgac agcagaagat
    21721 gattcccttt cttatgaaga aatcttccga acaaaataat cgttgtccaa acagaaaaaa
    21781 gcgattgaac aagtgaaagt tttgccttca tttgttcaat cgctttttat ttttattctg
    21841 ctgtattttc ggaatgcgca tttgcgtcag aatgcaagaa atagatcaag gtttgcaatt
    21901 cattcgtcaa atcaacattt tggatcaata catctgacgg agcattcaat cgagcagcgg
    21961 taaagttcaa gattcctttg attcctgctt ccgttaactg attgactact tcttgtgctc
    22021 tttcagcggg tatcgttaaa attgctactt cgatttgttg gatcttgatt tgttctgaca
    22081 tatcttccat tggataaacg gggataccgt ctacgatgcg cccaacgatt tcctcattca
    22141 catcaaaagc acaactgata cgtatgctat tactttgatg gaatttgtat tttagtaaag
    22201 cacttcccaa gttccctaca ccgatcagcg caacatttgt caattgatcg tcgtttaatg
    22261 tctttgcaaa aaagtgcata agatcttcta catcataacc atacccacgt tttcctaatt
    22321 cgccaaaata agaaaaatct cgacggatcg ttgcactatc tacttgaacg gcttcactta
    22381 attcagttga agacactttt ttctttccag cattatttaa aatccttaaa tagcgataat
    22441 acaaaggcag tcttttagct gtcgcctttg gaataatatg atctttcacg aaatgacctc
    22501 cacgtattgt ctaattacat ctttgatttc tccatcatag cagtatttat aggaaaaaat
    22561 caattccatt gctcagatat tgtgaaattt tattctttat tcatttattt atcatttctg
    22621 caaatctcgc agtataatgg aatttatggt agactactaa ttgaaaaata gttttttatt
    22681 tgaggagaat tcacaaagta gaaaagagga ttccatgata ttattacaag ccaatcagat
    22741 tgctcgccat tttggtgcag aagtcttatt tgaaaacata catttagaaa tcagtacagg
    22801 cgctcgtgtc gctttagttg gcagaaatgg cgctggaaaa tcgactttat taaagatcat
    22861 tgctggaatt gaagcacctg atgaaggaaa gatcgctaaa aataaaacag cgactctcgg
    22921 atacctcgct caggacacag gacttgattc caatgaaaca gtttggaacg agatgctgaa
    22981 agcttttgaa caagttagac aaat
//
LOCUS       DACBYO010000041        22480 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.041, whole genome shotgun sequence.
ACCESSION   DACBYO010000041 DACBYO010000000
VERSION     DACBYO010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.041"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(74..961)
                     /locus_tag="IVD26_001531"
     CDS             complement(74..961)
                     /locus_tag="IVD26_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6079514.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(958..1827)
                     /locus_tag="IVD26_001532"
     CDS             complement(958..1827)
                     /locus_tag="IVD26_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6079515.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(1964..3250)
                     /locus_tag="IVD26_001533"
     CDS             complement(1964..3250)
                     /locus_tag="IVD26_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6079516.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3523..4101
                     /locus_tag="IVD26_001534"
     CDS             3523..4101
                     /locus_tag="IVD26_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP6079517.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4101..5030
                     /locus_tag="IVD26_001535"
     CDS             4101..5030
                     /locus_tag="IVD26_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6079518.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5027..6763
                     /locus_tag="IVD26_001536"
     CDS             5027..6763
                     /locus_tag="IVD26_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6079519.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6826..7662)
                     /gene="pheA"
                     /locus_tag="IVD26_001537"
     CDS             complement(6826..7662)
                     /gene="pheA"
                     /locus_tag="IVD26_001537"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAP6079520.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7659..8168)
                     /locus_tag="IVD26_001538"
     CDS             complement(7659..8168)
                     /locus_tag="IVD26_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAP6079521.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8161..9456)
                     /gene="aroA"
                     /locus_tag="IVD26_001539"
     CDS             complement(8161..9456)
                     /gene="aroA"
                     /locus_tag="IVD26_001539"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAP6079522.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9469..10560)
                     /locus_tag="IVD26_001540"
     CDS             complement(9469..10560)
                     /locus_tag="IVD26_001540"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAP6079523.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10577..11743)
                     /gene="aroC"
                     /locus_tag="IVD26_001541"
     CDS             complement(10577..11743)
                     /gene="aroC"
                     /locus_tag="IVD26_001541"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAP6079524.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11745..12809)
                     /gene="aroB"
                     /locus_tag="IVD26_001542"
     CDS             complement(11745..12809)
                     /gene="aroB"
                     /locus_tag="IVD26_001542"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAP6079525.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12842..13864)
                     /gene="aroF"
                     /locus_tag="IVD26_001543"
     CDS             complement(12842..13864)
                     /gene="aroF"
                     /locus_tag="IVD26_001543"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAP6079526.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14523..15497)
                     /locus_tag="IVD26_001544"
     CDS             complement(14523..15497)
                     /locus_tag="IVD26_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAP6079527.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15478..17361)
                     /locus_tag="IVD26_001545"
     CDS             complement(15478..17361)
                     /locus_tag="IVD26_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAP6079528.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17379..19604)
                     /locus_tag="IVD26_001546"
     CDS             complement(17379..19604)
                     /locus_tag="IVD26_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP6079529.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19719..20753
                     /locus_tag="IVD26_001547"
     CDS             19719..20753
                     /locus_tag="IVD26_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6079530.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20820..21833)
                     /locus_tag="IVD26_001548"
     CDS             complement(20820..21833)
                     /locus_tag="IVD26_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6079531.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(21911..22099)
                     /locus_tag="IVD26_001549"
     CDS             complement(21911..22099)
                     /locus_tag="IVD26_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAP6079532.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         6395 a         4832 c         4079 g         7174 t
ORIGIN      
        1 aaataacaca cgtcccaaaa gtatcttttt acttggaaaa atgactttga aggaacgcgc
       61 ttattgtgtt tttttatttt acagagccga tcattccttg aacgaattgc ttttgcaaaa
      121 caaaaaatac gatggcagtt ggtaaagtag cgatgactaa tccagccatg atcattccat
      181 agtctggtgt ataggaagca cccatagcag ataaaacaag cggaaccgtc cgtttatcag
      241 gagattgcaa agctactaag ggccataaat aattgttcca gctactcatg aatgtgatga
      301 ttgcagccgc ggcataggta tttttagccg tcggcatata cactctaaaa aaaatactta
      361 gttcttttag accgtctaat cgagcggctt ctactagatc ttttggaaaa gatttaacat
      421 tttgtcgaaa gaagaagatc aaaaaagcag tgctaacaga tggcaggatg acaaccaaga
      481 aactgttgat tcccaaaacc gttccgttca attgtgaaaa cattcgatat aaagggatca
      541 tcaatgccgc aaaaggaacc atcatcgata gcagtagaat attgaaaatt aggtcttttc
      601 gtttactttg ataaatctca aatccatatc ctgccattga cgaaatcagc aatgcaaaca
      661 cagtggtcac caaagcgatc atcgctgaat tccaaaggga acgagtaaaa ttcagctcat
      721 tggaaaacaa attttgaaaa ttgatgatca agttactgcc aatctttatt tttcccgatg
      781 tgatatccac gggtgtattc gtcattccca aaaccatcca gacaaaaggg aaaatggaaa
      841 taaatgatag gatgcttaat gctgtatact ttaatactga cccaattgtc gaacgaagtt
      901 ctaatgcttg ttttttgacg ttggggcgtt cgattgtttc tttttctacc atatttttca
      961 tcgactttct cctcctactt tcgtttggat tatcgacaat atcacaataa aggaaacaat
     1021 aacaaaggaa actgctgccg catatccaaa attaggcgtg aatttataac tcaaattata
     1081 gatgtattga gatagggtgg tcgttgcatt tgctggtccc ccgccagtaa tattttgtac
     1141 ttcatcaaaa agctgcaatg tcccgatcgt cgaagtaatg gaagtaaaca aaatgattgg
     1201 ttttaaattt gggatcgtca ctttgataaa ctgctgccat ttagaagcac cgtcaataga
     1261 tgctgcttca taaatctccg aatcaatatt ttgcatgcct gaaaggaaaa aaatcatatt
     1321 gtatccagtc caacgccaag tgatcgaaag aatgatcaga actctcgccc aaattggatg
     1381 agtcaaccag ccaatcggtg tgtcaatcat accaatgccc aacaacaagt tgtttacaag
     1441 gccagattga gaaaatagac ttttcatgat cagagaataa ctgaccatcg aagtgataca
     1501 tggaagaaag atagcggttc gaaacaaccc tttatatttc aactttttat catttaaaag
     1561 gttggaaata aaaagtgcta gaaacaacat gatcggtact tgtacaagta aatacaggaa
     1621 tgtattaaaa aaagcttttt taaaagttgc atctgtcaac atccgctgat aattacctaa
     1681 cccgttaaat gtcatattga cagggggacc actttgaaaa gacgtgatca aagccaaaac
     1741 catcggaata aaaaccatga ttgatatcaa aatgactggc aagattaaaa aagcatgccc
     1801 gtttttgaat aaatctttct gcttcattct tttccctcca attctatcat tgattatcta
     1861 catgaaaaga caagaaagac aatatctgta aggcagacgt gatctttttt gtcttttcgt
     1921 ttgtctgatg aaaaagcgaa gaaattcact tttttaccac cgatcaatta gccaattgtg
     1981 cttctacttg tttttgtgta tctgctagta ccttgtctgt ctcttctcca ttgatgattc
     2041 gatgaagagc ttcagctacg actgcttcaa ttgcataggt ctcatgtccg taattcactt
     2101 ctggtatttc agatgtccat gttgaaaaat cgtcaaagat cttttgacca ctgtaaaatt
     2161 cagaagcttc ttgataagct tcttgttcat tcgcgctaag catcgtagat actagtccga
     2221 tttctttcgc aagagtgccc atcagttctt cattcgaagc aaacgttgct tctaggaaat
     2281 ctttcgctga atcttctcca gctactcctt tgatcacata ccagccagcg ccgccaaggt
     2341 tagaagcttg cgctttttgc agattttctg gaagtgcagg tattggtgca atcttccatt
     2401 ttccagattg gttttctgct ccttggatcg ttgaagaata ccaagcgcca gttgggctag
     2461 aagctactgc tcctgattgt atcgcagtta ctccagcatt ccagtcagag gtttgttcga
     2521 ctagatcttc tttcaaaaga gtggcaaaca attcaagacc atactttaaa gatgcattgt
     2581 cttggatcgt gactgtctcc ccatcttcag atgtatacca ttctcctgcc tgttgcataa
     2641 tcatccttac tcgaccaagg tcagaaggat tgacttcagc gattttcttt cccgtctttt
     2701 ctttgacatc tcgcgctact tgaatatact cgtcccactt cagattctcc atatcctctt
     2761 ctgtataacc tgcttctgcc atcagatccg tacgatagaa gtttgctgtt acgcccgaat
     2821 cgaaaggaac accgtatatt ttatctccta ctttgtttac cgcaaattta tacggtgcaa
     2881 aatgatcttc ctttacaata gcagacaaat tagcgaatgc atctggataa gaagtcaaat
     2941 agccttgtat cctataatct tcaatcaaga cgatattggg caatccttct gtattcccgc
     3001 tcgctaaagc ggtgttcagt ttctgaacga tatcatcctg agacatcgta acaacttcta
     3061 tctctgtttc ttcgttctca taaacttttt ttgcttcatt cactgctttg atattgaatg
     3121 tctcatccca cgcccagaca gtgacttttt cttctttgtc tgctgtacta ctagcacttc
     3181 cgcatcctgt taagaaacct gatgctgccg ctaaacaaac gactccagca attaactttc
     3241 tgatgttcat ttttatccgc tccttttcca tccattagtt gtttacgttt gctacattca
     3301 tcataccaaa atttgaaaac ggtttcttta ttattcagat acttcaaaaa tttctcctaa
     3361 aataataaaa aaatacaaat caactatgac aaaaggaata atcttagcat ctagaccaaa
     3421 gatcgaaatg gtgaggtttc tttaaaataa aaatatcctt gcattttctc ctagaaataa
     3481 gtatttttaa attacaagac tattcttaag gcgggtaaaa aaatgccaat acgcgtaatt
     3541 cttatcgatg atgaacagac gattttagat ggaatgaaac agttgatcaa ttggtctgag
     3601 cacgggtttc aattaatagg gactttttcc agtccgctga aagcgcttga tttttctttg
     3661 gtacatgcaa tcgatatcgt ggtcacagat gtaatgatgc ctgaattaaa tggaatcgaa
     3721 ttatcgcggc tattaaaaca gcaacaacct gaaacacaga tccttatcct ctctagctat
     3781 gatgaatttg atatggttaa agattctttt aaagaaggcg tcgctgatta tcttttaaag
     3841 cctcgattga gtcctgattt ttttctaaat tccttaactg ccgtttcaca aaaaatcaaa
     3901 aaaaagccca acaaaagccc aatcaccaat cgttatgagc agatctgcga gaatctttca
     3961 cagcagattg ctggacaaac tcgtccattg cttgaccctc ttctttttga acacaccttg
     4021 tttttctgtt atataccgaa aaacggccat tcagttcaaa acaaggctct aaacaaaaac
     4081 agtcgatcac ccattcattg atggatagcg acgattcgtt tactatttat cctgtttcta
     4141 ccttttcgga agaatccggc tatgtaatca atactgattc caaagataca cttaggaagt
     4201 ttgttcaaaa gtttcgtcaa gaagtttttc caggtgattt ttttgttgtt tctgattctt
     4261 ttgcaatcca agatatcaat gaaatattcc aagagatcag aaattgcacc aaaggacaac
     4321 gtttctatca taagggaaag aaccttgctt atcagcatga acttcttccg ttattaacca
     4381 accacgagca gcaagcaagt agttatttaa caaaaatcgt tcataaagac tacgctttag
     4441 ctgtcaaaga acttgagaat ttcttcacga cgatattgga acagcctatt gatccagctt
     4501 atttgaaaca tgaggcaatc aatcgtttct atgcattact caacgctttg gctgacgagc
     4561 atgttgggaa tgaagaactt tctttgctca agatcgccct tccttcttta ttagccgatg
     4621 ctgagtattt cgaagatttt tctattcttg tcaaagaaac acttgagaaa ctcacccact
     4681 tttctgcaaa tgcaaaaaaa gacaatttcg atatcttgac tttgatctac gagttcgtcc
     4741 aggaaaatta tgagaaagaa atcaatttac aacttttatc cgaaaaatat catttttcat
     4801 atagctatct ctcagccatc tttactgaaa aatttggtat caacttttca aaatatctaa
     4861 aaaaagtccg tatcagtaaa gccaagctct ttttgacgga aacacggctt actttgacgg
     4921 aaatctgtga gaaagtcggc tataccgaac tgggttattt ctccagagtt tttaaagaag
     4981 agacaggaat gacaccttct caataccgta aaggaacttt tgtaaaatga gaaaaaaaat
     5041 caaagagcat gaactctttg ccaaacttct gttcattttg ttcatcggtc tttttctgca
     5101 agccatcgtc atttctttgt ttatttatca tcgatcaagg gatgcctata tccagctgtt
     5161 caatcaatcg aatgatgtgg tactaaaaaa gattcaatct gaatttgaaa gtttgaatga
     5221 tacaatcgag aatacattag ccgcttttga ttctaatcca gctgtcaaaa gctatttttc
     5281 caatgatcca gcccaacata tggaacagct tcagcaacta agaacaatcc aaaaaatgaa
     5341 tgactctctt tcaaaaatcc atccaatgat cgattacgat gtattgatct ttggagaaaa
     5401 tggaagaact tttgtcggaa acgacatgct cactgccgta tctgccgatt ctttttttca
     5461 atctgcgatt gctcagagag tgaatgaacg tgctgctgat acacaaatgc tttttgcaca
     5521 ccacggattg actcttcgcg ataagaaagc acccagcgtc ttctttgtca aaaaactgaa
     5581 aaatacattg aatcacgttt acggatatgc tgttttatcg atctcatcca agcaactagc
     5641 gaatcttttt caatctgtag taaatcctga gatatcgaag atctccttca tgaacgaaga
     5701 acagacgatc atcgcatcaa atgaagaaaa tacaattggg agccgatcaa tgattttcaa
     5761 aaaactaaca gtaggtgaaa caacgatttc aaatggacag cagttgaccc gtcttcctct
     5821 gtaccgccag gattgtacat tactcagtca agtcgatctt cattctttat ctaaccaaat
     5881 gggcgtgatt tttccgatta ttttgtataa tatcgtgaca cttgcttttg ctggctcatt
     5941 ggtatttatg tatttggatc gacacacaaa atcgatctac cgcttgattg attcgctaaa
     6001 acggctagag gaagatggct taaaagctac tgttcctgta caaggaagcc atgaagtcca
     6061 attgctaggg aatacgatca atcaattgct aagtaatgct cagcatcatt atgaacagac
     6121 gatccaagac gaaaagaaga aacgttcgct tgaaatccaa actatgcaag cacagataca
     6181 gccccatttt atttataata cgctgactag cttgaaattt ttgatttggc agaaaaaaac
     6241 agatgaagca gttcaaggaa tcgacagttt cattacttta ctaagaagta cgattgggaa
     6301 aaaagaagaa gtgattccag tcaaggaaga aatcaaaagc gtacaaagtt acatcgatct
     6361 tttgagtatg cgatatggcg aaagaatctc ggctaaaata atgattcctg atgaactgca
     6421 gtcattatct atgccgaata tgatccttca accaattatc gaaaacgcct atcttcatgc
     6481 ttttcacaat aaaacgcaag gattcatcac ggtgtacggc aaaacaaaaa atcagcttct
     6541 tttattcgaa gtgattgata acggcgatgg cttcgatact gaaaatacca aacaaaaaaa
     6601 tgatcatttt tcaggaatcg gcatcagcca tgtagatgag cggatacgcc taatgtatgg
     6661 cgatgcatat ggcttaacga tccaatcagt gattgggaca ggaacgactg taacgatttg
     6721 tctaccgctt cttcctaaaa atcaatcaga atatcaaaaa taaagaatag ccaagcgctg
     6781 atttttttat tttaagttaa ataaatcaat cagtattctt gactttcatc tacgcgtctc
     6841 ttctactgtc agcactggat aacagcccaa tatttgactt tctcctccga gcatcttgat
     6901 ttcttggagc gcattctcta ctaatgtcat tggacggtcc aacaacaaat cgatcacgaa
     6961 aaaatattct cccaagctag ttttcaatgg tcgggattca atcttactta agttgatttc
     7021 ccgccagcca aaagctgcca gcattttatg aagcatccct ggccgattag caggtagtgt
     7081 caagatgaca ctcattttta ctggagctga ctgctggctg gtcatctttc ggtcaccgac
     7141 gatccaaaaa cgtgtctggt tcaactcatt atcttggata ttctcagcta agatctccaa
     7201 tccaacatgc tgtgctgttt ctaatgaagc aatcgctgct gcgtcttctt tcggatgttc
     7261 tgctacatac attgctgcag cagttgttga ttctgttgct actaaaggaa cattaggata
     7321 atgcgtttct aaaaactgtt gtgattgtgc tagtgcttgt ggatgtgaaa ggatttttgt
     7381 aatctttgtt gctggattgc ctaaaagctg ctgcttgata ggaagaacga tttcactttt
     7441 aacttcgact tctggatgtt tggaaagaag atcgattgtg tgatgaacag ctccttccaa
     7501 tgaattctct acaggaacga cagccagatc gacttgtttg cgaaacaaag cgcgcaaaca
     7561 aacagggatg gaagcatacg cagtcaattg ttctgtagga aatagctgac aagccgcctg
     7621 ataagtgaat gaactttctg gccctagata gctgacgttc atatgctttt gatcctttct
     7681 ataatggtat cgatgatctt ttctggtgtt tgattggtcg tgttgattcg atgtgtcgca
     7741 ctttcttcat accaagaaag tcgttgtgcc aataatgctt ttatttcttc tcttgttttt
     7801 ccaagagcta aaggtcgaat agacgtttca tcttgttgga tacgatcaac tagacagtcc
     7861 gcttctgcct ctaagtaaag aacaatcggc tgtgttttta aaaaacgccg attttctgca
     7921 ctttggacaa tccctccacc agtcgcgata attttgtctt catttgacag ctttcttaaa
     7981 atatctgact ccacttttcg aaagcttttt tcaccgtaat agtgaaaata ttcggcaatc
     8041 gacaattgga tatgttcctc aatctttgta tctaaatcta catactcttt ttgtaaacat
     8101 tgagctaacc ctttaccgat tgttgttttt ccagcgccca tgaaaccaat cagcaaaatg
     8161 ctagccatga gcttctcctc ctgacacaag ttctgctaaa tcgtcaaaaa atgccggata
     8221 agagattgaa acagcttcag ctccttctag ttcgcaaggt ccatcagcta tcaaagcagc
     8281 tacttgcagc atcataccga ttcgatgatc gcctctgctg gacacttttg cgccatgcag
     8341 aggtgtcggc ccatggatga tcagaccgtc tgctgtcgct tttatctttg ctcccatttt
     8401 ctgtaattct tctgccaccg catcaattct gttggtttct tttactttta attcttctgc
     8461 gtctttgatg atcgtgattc cttctgcttg agtagccact aaagctagaa tgggcaattc
     8521 atcaatcaga cgcggaatga tttctccacc aatcgttgct ttcttcaaat gactcgtctt
     8581 gacacttaaa tcagccgatt ggttctgttc attgtgattc gtctgggtaa tcgctgcgcc
     8641 catctcctcc aacacatcta agataccagt tcttgttgga ttgaccccga cattttttaa
     8701 caacagttgg ctttccggaa caagaagtcc tgctgctaga aagaaagcag ctgatgaaat
     8761 atcacctgga acagttatct gttgaccagt taatttttgc ggtccggtca ctatgatcgt
     8821 tttatcttcc actgtgatcc ttccgccaaa ttgacgaatc atttcttccg tatggttacg
     8881 ggaacgttct ttttcaacga ttacggatgt gccttctgct tgtaatgccg caaacagcaa
     8941 agcagatttg acttgcgcac tggctacagg catattgtat cggataggtg ataaagagcg
     9001 ggttcctgtc acagtgattg gtagatactg gtcattttct tctccttgca agtcagcgcc
     9061 catctcgcgt aaaggttcca tcactcgccc cattggacgt ttagacaacg aagcatcccc
     9121 gaacagagta gtcgtaaaag gctgtccagc caaaataccc atcaataaac gtatggtcgt
     9181 accggagttt cccatgtcaa ttgattcggt tggttggaca aatgagtggc taccgcgacc
     9241 atgaatcttg atcacctctt cctcttcttc gatctcgaca cctaattgtt ggaaggcatg
     9301 taaagtactc agacaatctt ctgcgcgcaa aaaattttgt atagtcgtcg ttccttcagc
     9361 aattgctcca aacatgatgc tgcgatggga aattgattta tctgctggta tcctaacagt
     9421 ccctcttaat ccatgtattt gttgtaataa ttgcatttat ccagcctcct atttgatcca
     9481 gcaatgataa ctggtattag acataatgat tctttttgct tgtaacaaat cctgttggtt
     9541 tttaaaactg atttgcagta ttcctaaaat atcttccctg gtctcttgga tcttcaaatt
     9601 aatcaaagaa actcccgctt ttccgatcag tccagttact tctgcaataa cgccaggttc
     9661 atctggcaca tcgataaata aatcaaaaaa ggcaggaatc gcgccttgct tatggacagg
     9721 caactggtct cgactttctt ttgcccgatt gaaaaaagaa aagatttccg attggttctc
     9781 agtcatgatc cattctgcta tttgtgtcat ttcttgttgc caatctgcca atcgttccaa
     9841 taatatctgc ttattgctca acaaaatatc tgtccacatg acaggatctg aggaagcgat
     9901 cctagtgata tctcgaaagc ctcctgctgc cagttgtttg gctcgcggat actcttgatt
     9961 gaattgttct gcctgattga ctaagccagc tgccagaata tgtggaaaat gacttagcat
    10021 tcctgttata cggtcatgtt ctcttgctgt aagagttaca tattttgctt tggttccgca
    10081 aaatagttct tgcagttttt caacatcttt tttcgtcttt tccaaaggtg taaagatgta
    10141 ataggcattt tcaaatagtt tagcatctgc tgcctgtata cctgatttat gagaaccagc
    10201 cattggatgt ccaccgacaa accgaagatt tttctgctca gcggatgtca cgacttgctg
    10261 cttcgtactg ctgacatccg taatgatgac gtgatcagac aagttgattc tttcaaggac
    10321 atcaagataa gctaaggttg tacggacggg aacggctaat aagataacgt ctgcttgttc
    10381 tgcacctgtt tcaaaatcac ttgcaacgta atcaacgatc tgctgttcta ctgcttgctc
    10441 acgggttttt gactgactat cccaaccaac tactatcagt tctggattgg tctgacgaat
    10501 acaaagtgcc atagaagcac caatcagtcc aagccccacg ataaaaacat gttgtgccat
    10561 cttatttgcc ccctttttag taatgtttca agtagtcacg gtactccttc actgcagctt
    10621 tcaactcaac aagcgaatca cttgggaatt ttgacaatag ctctgtcgct accacagtgg
    10681 ctacaacatt ttccgcaacg acgctagctg caggaactgc tgtactatcc gaacgttcta
    10741 cacttgcttt gtaaggttct tttgtatcga tatcaacact ttgaagtggc ttgtacaatg
    10801 taggaatggg tttcatgacc ccgcgaatga caagtggttc gccattggtc attccgcctt
    10861 cgaagccgcc tagattattg gtacgtcgga aatagcctct ttcttcttcc cataggatct
    10921 catccatcac ttctgagcct ggtaatgaac cagaagtgaa tccgacccca aattctacgc
    10981 ctttaaaggc attgatacta accacagctt gtgcgatttt ggcatctagc ttcgtgtccc
    11041 attgtacgta gcttcctaat ccagctggaa cgcctccaac gagcacttct acaattcctc
    11101 cgatcgtatc tccatttttc tttgtctgat cgatcaaatc ttttattctt tgctcaactg
    11161 ctggatcaac aactcgtact tctgacgctt cagaaatttc tttgatttct tgaatcgaga
    11221 tatttccagg tatttctgct tggattccac caagacaaat cacgtgtcct gctacgatga
    11281 tgtcaagttc ttccagaatt ttcttggcaa ttgcgccgat tgctacacgc atggtcgtct
    11341 ctcttgcaga ggaccgttca agcacattcc gaagatctcg atgatggtat ttcataccgc
    11401 ctaccaaatc cgcgtgtcct ggacgcggac gtgcaactcg ccgcagtgat tggtcttttt
    11461 caggcacttc tgctacagac atgacagttg tccaattttt ccaatcttta ttttctacca
    11521 ctaaagtgac aggtgaacca attgttttgc cgtgacggat gccagacgtg atccgaacac
    11581 gatctttttc gatcttcatc cttcctcctc tgccgtaacc agcttgtctg cgagcgagtt
    11641 cgtgattgat ttcttcttct gacagaggta atcctgctgg tagtccttca ataatggctg
    11701 ttaattctgg tccatgggat tctcccgcag tcatataacg catcttacag tcctcctaag
    11761 taatctttga atgtctctgt gggaacagga acgatttttg cttgcccaat cttttctagc
    11821 aagatgatat tcaattggct tcctcttgct ttcttatcat gggttatcgc gtggaataat
    11881 tcatctggat gacttagatc gtacgtaatc ggcagatgga atttttgaag tatcctttct
    11941 aaagcagctg tcgatccagt tggagacaag ccgatttttt ctgcatgaga agtgatggct
    12001 accattccaa tagctactcc ttctccatga ctgactaccc catatcctgc tgtattttca
    12061 attgcatggc caattgtatg accaaaattt aaaataagtc gatttccttg gtcaaagaca
    12121 tcttcttcca ctacttttcg tttgatttcc aacgtagcag taatgattgg aacagcatgt
    12181 tccagaagat ctttttcgtc tttcagctcg ttcagctgtt tccaaagcgt tgcatctgct
    12241 atagctgctg atttgatgat ttcagcgatt ccttctcgta aacgacgtac cggcaaagtt
    12301 tttagaacct caggatcaat caatacacca gctggctggc taaatgttcc gacaaggttt
    12361 ttcgctttgt ttgtattgac tgctgtcttc ccgccaatac tagaatctac ttgtgcaagt
    12421 agcgtagtcg gaatttgaac gaaatggatc ccacgcatga acgtcgaggc cacgaatgct
    12481 gctagatcac ccaccattcc tccaccaagt gcaagtatcc catcgctgcg ggtaaaatca
    12541 ttatctgcta aaaaatcgta taactcagct gcttgttcta aagatttact ggtctcaccc
    12601 gccggtacga ttgaaaggac tggttcaaaa ttagcttgtc tcaattggaa catgattttt
    12661 tctgcatata gtggagcaac gtttgtatca gtgatcacag ctactttttg aggtctccaa
    12721 atcgtttgaa gccatgatcc agcctgttct agtgcgcctt tttcaatatg aatatcgtat
    12781 ttttggttat caacatgtac agtaagcatt cgtttcactt ctttctttta aaaagctgga
    12841 attaatcgag tgtctgaatc ttttccattg cttctttcat gatcgcaact tctttcatca
    12901 tgcgtgagta agtcttttca ttcaacgatt ggggaccgtc tgaccaagca tttgcaggat
    12961 caggatggat ctctacgatc atgccatctg ctccgcttgc cacacccgca cgagccattg
    13021 gtggtacaag ttcccaaatt cctgtaccat gacttggatc aacaatcaca gggaaatgag
    13081 ttaatttttt catcaatggg acagcactta aatcaaacgt attacgtgtc gctgtttcgt
    13141 aagtccgaat cccacgttcg ataaaaatga caggagattt gtcttcgact gcaatgtatt
    13201 ctgcagcatt aagccattca ttgatcgtac cggaaattcc acgtttcaat ccaacaggtt
    13261 tacctgtttt accgacagca gatagcagtt taaaattttg catattacgt gcgccaatct
    13321 gtaggatatc gctgtactca gccaccatat cgatatgccc ttcatccatc acttcagtaa
    13381 tcactttcat tccaaattca tcagccgctt gacggatgta tttcaatcct tcttcttcta
    13441 aaccttggaa agcatatgga gaagtacgtg gtttgaaggc accacctcgc agaatttttg
    13501 cgcccccggc tttggccatt cgcgcacatt ctctgatttg gtctaatcct tcgatagaac
    13561 aaggaccagc catcgtcacg aaactgccgt caccaatttt tactccgtct acatccacga
    13621 ctgtattgcc aggatggaat tctcgagaag tcaatttgta tgtgtttaaa atacgcacag
    13681 cattttctac tccttcatag cgtgtaaatg ctccttcttg taaacttcgc gtatcacctt
    13741 ttagtccaat cactactcgt tctgttcctt gatcgattga gactttgaat ccttcttttt
    13801 cgatatgatc gacgactttt tttatttgtt cttccgttgc ttcttttttc ataattacta
    13861 tcattgtttt tcccgctttc ttttgtttac ttatctatct tggctgattt tctctacttt
    13921 ttcaaggtgg ttttacatta attcctacta aatgaccgtg tcctgttgtt ctcattttcg
    13981 ctccttcttt cctacttatg acccagataa tcaacaaaaa aagatgtccc tgtaggaaat
    14041 tgcctctaca gtgaacatct tcaacgagcc ttaaaaagcg ctgcaaaaat ataaaatagc
    14101 cactatagat gaatttctct acgtggctgt aagtcgtgtt taaaaatctt tagccatcat
    14161 agatacaaac ctggtttgtt tgtacccacg aagtcatgaa tacaaaccta tctaaaatag
    14221 ctaaagtaat acgtattcag ttttgtaagt tttctagatt tcataaaaaa tcgctccaaa
    14281 ctgatgtaag aattgtacct agtatagaca taaaaaaatc gactgtcaat catttttatg
    14341 aaactttttt taattttctg atagttaact ttgtttttca gaaaaataac aattggtttt
    14401 attgaagaaa atagtcatga acaaaagtat ctgagaactt ttttactctc ttgttcatga
    14461 catatagaat aaagcagctt tgtcttgtaa actccgtttt tcaaataata atctaaagat
    14521 tgctactgaa taataaagcc gatttcatgg tcctcttcgc tgctgattcg gtaaggtgac
    14581 tcaacatccg ctccccagct attgataccc ccgactcctc ttacttttgc aaaaatcgta
    14641 agaaccgttc gtctttctgg cggtagttct tctatatgtg ttgcctgttc cagttcttct
    14701 gctttgaatg gtaaagcgga aaaagcaaat ggcgtatcct gctgttcaaa tcgcaacgaa
    14761 aaatcttctt gatctttatc cgtattatcc aacgtttgat ttcttgttag ttctacccat
    14821 ttcgtttcca tatgcatgcc gcattcttgg ggaacaaggt atggggaaac ggggagtcct
    14881 gccactttat aaataccttc gacaccacca gccatccgat ccggatatgt ttcccctgat
    14941 aggccttcat actcaaaaaa ttttgctttc gttggcataa tgaaccttaa acccaatgcg
    15001 ggtaattccg gtaatccttt ttgtccataa taatgcatat tgacaagcat tttaccctct
    15061 ccagcgattt ggtaggaaat tgtcacttgg gtttttggta ctgtgttgat ttccagtgta
    15121 aaaatgattt caaccgtttc agcgtattca ttacttgaat attgattatt tactggagca
    15181 atcggcaaat cgatcttttt attgtccacc agtacttcta tttctttgac ttttggatac
    15241 aatccggctc ctaaccacat accggattta aatccaaatc cgctacctct gtcattatcg
    15301 gtcgttgctc gccaaaaaac tggaagtgtt tcccggtata gccattcttt tccgttttta
    15361 ttgagcgatt ccagtccgcc tcttgtataa gaaaaaatat aatgcgtatt ccccgatttg
    15421 acacctaatg tacagtcgcc gaagacgatt gcaacttttt ccgtatccat atgactttta
    15481 tttactgtat ttttcataat aatatcttac ctcctgcatg gcgggttttt cttgtccatc
    15541 tgcaaaaacg atcccattcc ctgagaattc atagtcactt ggtttatcgt caaagtcacc
    15601 gccatagcgc atcacttctc tgcctgtgat tggatcagtc acttggatcg cctgatcttt
    15661 aaaatcccat atatagcctc cttggtacat ttcataacga tcaagcaacg tcatgtaaga
    15721 atccattcca cctaacgaat tccccatgtc atgcatatat tcacataaga tgaacggttt
    15781 ttccgcttta ttttcaaggt agtcaatgat ctcttctggt ggcgcataca tgcagctttt
    15841 tacatctgaa atcgaatctt cgaatgctgg atttggaaaa ttcccttcat aatggacaag
    15901 tcgatcgggg tctacttttt tgaagtaatc gttcatttgt cgaatgtttt cttccgcata
    15961 agattcattt ccaagagacc aaaaaagaat acttggatgg ttttttaatg tttcgaaatt
    16021 cgtttttgct cgatcaagaa cagccgcctg ccactgaggt actgcacctg gtacgttgta
    16081 agaaggctca aatgcgccca ttttttgcca tgagccatgg gattcgaggt tcgtttccgc
    16141 catcacatgg attcctgctt ggtcgcataa ataataccaa gtgatctggt tggggtaatg
    16201 agatgtccgt acgccgttga tctttgcatt ttttatgata gccaaatctt tttccatatc
    16261 ttctatagtg atggcgcgtc cttttttcgg atgccactca tgtcgattta ccccgttgat
    16321 aatcatccgt tttccattga agtagatgat tttatctttg atttcgattt tacgaaaacc
    16381 gaaggaatag tcaatatact ccgttactct tttttcttcg tctatcgtct ccaattcaag
    16441 cttatataaa ttgggctgaa aatgccccca cagtgccaca ttttcaaatc catcgatgcg
    16501 aatcgtcatt tgctctttta acggatattg ctgttgatag atttccttcc catcaggatc
    16561 tagtatcgct acattcagct gactgttttt ggctacttgc tcaaaagaca aatctacttc
    16621 aagtttgcca ttttgacatt tgtcatctaa gcgaggtttg atccaaagat cttctaaatg
    16681 gttttgtcct cgagcaacta agaagacatc tctgaagatc ccaaaaaatc ggaaaaagtc
    16741 ctgatcttcc aagaatgcag ctgtacttct tttgtaaacc tccacagcta gaatattttc
    16801 ttcttccaaa taaggtgtta aatcaaattc agacggagtg aacgaatctt cggcataccc
    16861 gataaaatga ccattcaacc aaataaacat tgcttgttct acaccagcaa aatgaatcga
    16921 gatttgtttt ccctttagac cttcttctaa tcgaaaagtc gtcaaatacg aaccaaccgg
    16981 attgtcttta gcagctgaaa agatcccttc cgcctctttc tcagggcttg tcgtgaaagg
    17041 gggacggcga aatacatgtc cctcccacgg atacatcgta ttgatgtaat ggatcttgtc
    17101 ataatttgct aattcaatat gactaggaac agtgatttca tcaaaagaac aggcatcaaa
    17161 atctttttta taaaatgttt ttggtcgtac cgaaggattt ggcgaataac aaaaacgcca
    17221 tgatccattt aaagactgtt taagggagga tgtggtttct acttcttccc ttgttgcata
    17281 acaaacatga tcgctatgtg catttgattg gttcactcta aaaacttgtg gatcatctaa
    17341 ccattttata tttgctttca tacttttttc cttctctctc ataacttttt gaaatgaagc
    17401 agttctgttt ggaaatcacc ttgaaaatcg gggaagtaaa gtccaactgt catcaattcg
    17461 gcccccgaaa atatccgctt cgaggtctgt tcctgataaa gtgcctcatc atctaacccc
    17521 atcagatata cttcatggaa cgctggttga gctgaagcta gtatcctccc taaaaacaca
    17581 atagcttcat cttgtttagg agacacaaac atccatgcgg caatattttc ttcaaaagga
    17641 ctcgccaaac gataataatg gccatactgg atcaccggac gaatcgtttg ataggatata
    17701 atttggtctt ttacttgctt tttttcttca ggagacagct ttgtcaaatc cagttcataa
    17761 ccaaaaacag cgctcatagc tgtttctcct cttgttttca acgaagtaga tctgtcggtc
    17821 tgatgatttg gtacagctga tacatgagct gtgatggacg aaatcggata agcaaggctt
    17881 gttccatatt ggattttcat acgctccact gcatccgtgt tatcacttgt ccatgactgc
    17941 ggcatataat aaataaaccc ggcatcaaac cgtccacctc caccagaaca gccttcccat
    18001 aagatttccg gataatcagt tgtcaaatgt tcaagtagtt cataaagccc gagcatataa
    18061 cgatgcgcta cttctccttg tctctgtggg tcaagggtaa tcgaatagac atctgaaagc
    18121 gaacggttca tatcccattt gatgtagtca agaggaatcg tatctaaaat ctttctcatt
    18181 tgtttctcaa tcgtctgccg aacatctaac cttgtaaaat ccagtacatg ttgtgatctg
    18241 gaagcagaag gcattctacc tggctcctgc ataagaaaat caggatgtgt tcgatacagt
    18301 tcagaatcaa ccgagatcat ttcaggttca aaccataaac caaatttcaa tcctttgcta
    18361 tgagcataat ctgctatttc acgtaatcca tttgtcaact tgccttcata ctcgaaccag
    18421 tctcctaatg aagaattgtc cgcatctctt tttccaaacc agccatcatc taatacgaac
    18481 atttcgatgc ctagctcctt tgcttcatca atgatcgcct tgattttttc actattgaag
    18541 tcaaagtaag tggcttccca gttattgacc agaatcggcc gttcagcaaa ttgatgacga
    18601 cctcttgcga ttctttcacg tagcaactca tggtggatct gactcatttt gttcaatccc
    18661 tgacttgagt aagaaaggat catttcaggt gtttgaaaag actggcctgc attcaattcc
    18721 cacgaaaaac gatggctgtt gatcccaccg acgactctca attgattgat ctgatctttt
    18781 tcaagttcga aagaatggtt gccggaataa acaaattgaa gtccgatcgc ttctccagta
    18841 ttttctgtcg tatgatgatg aactaaagca ataaagttat tcatatggtg actgctcgtt
    18901 cctcgacggc tttcaaatac ttttgttcca gataaaacag attgccgtga aatctgtctt
    18961 tcattgacat gtgctcctgg caaagcaatg acttcatcaa atcgcctagt atgggcaaag
    19021 tctagctgga aactagccgc tttttctagt ttgattgttt ctccggtttc atttcttatc
    19081 tttacagatc gtgtgatcac tgctctatca gtaaatatgg tatagaacaa atcgaaataa
    19141 atcgctgttt ctctatcctt aagtgaaatc accaacgttt gtgcctctga cttgtccatc
    19201 acataagttt gaggcaagcc ttcgatctct ggcttcccat ctgtaatata atggctgtca
    19261 tatctcagat ccagtaagtc tgatccattc ttgcgctgaa tgatcgatgc gggcgttcga
    19321 aagtccatgc tgccatgaga agagtattct tgcggtagtg tatctttcga cagagaccgg
    19381 tcaggattta agggaacatt tcctgaaaat ccacgatctc ttcggggata atttttattg
    19441 tctttgtact gcttgactgg tttgccaaaa taaatatgcg ccaatacatt gctttcttct
    19501 atctttatca gataagaaag aaatgtattt cgtaaatgga agactcggct cttttcatca
    19561 aataagatga aatttttatc tgtttttcta tgcgtaatat ccatcatttc actcccaaca
    19621 aaacggaaac cgtttacttt tttttataat tcctgtatac tgtttactaa acaattttgt
    19681 caataaaaat tttttatttt tttgaggagt gtgtaaaaat ggttggaatt agagatgtcg
    19741 cacgaaaggc aaatgtctct cctgctacag tttcccgtgt gttgaataac gatcagacga
    19801 tccatgtggc tcagactact cggcaacgga tagtagaggc agctgctgcg ttggattatg
    19861 acatcagtac tcgtaaatat atcaaaaaga gaatgccttc gattggtgtg atctctacga
    19921 tcggcaaagc gagcgaagaa caggatatct attacaaaca tttgcgagta gggatggaag
    19981 aagaagctcg acgtctgcat ttagggatga atcgaatcta taatctatct gataatccta
    20041 aacaatggga agatctagat cagttaggtg cggtgatcgt tgttgggact gttacgaaag
    20101 aatcgattac cgccttgtta aaacaaaaca tgcaaatagt cgtcgtggat aaccctgaca
    20161 tccagcaaga ggtcgatatg gtgtatgcag atcttgaacg gatgactaaa accgtactgg
    20221 aattgttctt agaaaatggt cataaaagaa tagcctatat cgggggatat aaagtcgata
    20281 tggatgaatt cggtgggaag cagatttcta taaatgaaaa gaggatgcgt gcctatcagc
    20341 attttatgat cgatcatcac ttagaaaaat atatgtctta tcatctaggt ggctggacag
    20401 aaaaacaagg tgaggtactt gcgactaatc tattagaaaa tgaatcccct cttcctactg
    20461 ccattcttgt cgggagcgat ccaatggcaa ttggtgtcta tcgggcattg aaacaaaaaa
    20521 atatccaaat tggagaagag attgttgtag caagctttga taatatcgag acaatcgcaa
    20581 acctctcccc tggcttgacc agtgttcaaa tcaatgcgaa atcaattggg caagcagctg
    20641 ttcgaatggc attggagcga attgacggta tacgggacga accaatcatt ttgacttatc
    20701 ctgcacgatt gattgttagg gaaagtttta tcccaagaac aaaaaggtat tgaaagagag
    20761 gttgtgaaaa gccgcttcgt ttcttcatac tcaaaacgaa acggcttttt cacaacctct
    20821 tacttatact tattcacaaa atccaatgtc tgctggtaac aattttgcga ttcttttagc
    20881 gtgtaatcaa attggtattc atgggtaatc tctttttttg tatctgtata aaacaaggat
    20941 tgcacgggta cctttaattc tgtcaaccga ttttctaatg cttgaccttg ctcctggaat
    21001 gagtatgcat ttccgtcagt tatatacgtt ggcggaaatt ccttagaaac atggtcagcc
    21061 acactagctt ctttcaattg ctcactcgtt ttccaatctt ttgttccaat caacgaccac
    21121 gcaacggttt tgacgaaaaa cttcataaat cgatcatccg aatgctgctg tgctgttagc
    21181 ttcaaatcaa caggtccgca ataagaaatg gttcctttca gactatcttt tggaagtagc
    21241 tgtttgattt tcatttgttt agcatacgca tcattcgttt gtatagctgc atattgcaat
    21301 gcgatttgtg aacctgcact atctccacca aaaaataatt gttccatgtc tagcaatttg
    21361 tcgtcttttt cttcagctaa taaatctttg atcagttcat tcacttgaag aacttgatta
    21421 gggtattctg aatcaggcgc taattcataa ttcatcgcaa ccactgcgat gttggcgtct
    21481 gaaactaatt ttgtcgcaaa ttctttgaca cccgatttat ctccgccgac gaatcctcca
    21541 ccatgtaccc aaaatagaac aggaacaggc cccttgctgt tttttggata gtagatgtca
    21601 taagtattct ctttatactt ggactcatac gtcaaatctg tttttttcgc cacgtttttt
    21661 tctgcttgat cgaacgtttt tttatcagtg atttgaacag tatttgaaaa catatggttg
    21721 atcaagaatg ctccaggtct gggggaaagc tggaaggcaa gaaagattgc aaacgcgatc
    21781 ccaagaatga ttccgaagaa ccatccgata aatttaagaa ttttcttttt cataaggctc
    21841 cctcagtagt tagtattaag cattctgatt ataccatagt gttatttcct atcaagctct
    21901 cctagatgat ttaatgattt tccccaaact tcttctgcaa tgcttttgac aaaagaaatt
    21961 ttttccattg ttcttcaaac aaaacatttt cttcttctgt tgaagcaaat ccacattgag
    22021 gacttaagca caaacgatcc aaaggcagat atcgtgtcgc ttcgtagatc cggtcaatca
    22081 cttgctggtg ctcttccatt tcgccatttt tcgttacagt caaaatctaa gacaactaat
    22141 ttatcttcag agactttctc taaaagaaca aaactcccag cacgttcact atcgtattct
    22201 aaataatagg cacggacatt ttcttgagta aaataatggg tctgctacgt cgtcatcccc
    22261 cctgatgccg ccaaaatcga ataataattt ccgcgtcaaa catgtatatt tagtgttgaa
    22321 tcatttgaga atatgaaaat aaaaatcttt ttgatcaatc agttaatcaa attgaaataa
    22381 cgaaaaatct gagacagaat gacgttcatt ctgacccaga tttgattttg cacaactcaa
    22441 cagtccttat tggcaaatcg ccaaaataat gtagactaac
//
LOCUS       DACBYO010000042        22394 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.042, whole genome shotgun sequence.
ACCESSION   DACBYO010000042 DACBYO010000000
VERSION     DACBYO010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22394
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.042"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(282..749)
                     /locus_tag="IVD26_001550"
     CDS             complement(282..749)
                     /locus_tag="IVD26_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAP6079533.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            complement(824..1264)
                     /locus_tag="IVD26_001551"
     CDS             complement(824..1264)
                     /locus_tag="IVD26_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6079534.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            complement(1294..1587)
                     /locus_tag="IVD26_001552"
     CDS             complement(1294..1587)
                     /locus_tag="IVD26_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079535.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            complement(1618..1812)
                     /locus_tag="IVD26_001553"
     CDS             complement(1618..1812)
                     /locus_tag="IVD26_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079536.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            complement(1918..2370)
                     /locus_tag="IVD26_001554"
     CDS             complement(1918..2370)
                     /locus_tag="IVD26_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079537.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            complement(2396..2857)
                     /locus_tag="IVD26_001555"
     CDS             complement(2396..2857)
                     /locus_tag="IVD26_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010781228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6079538.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            complement(2858..3061)
                     /locus_tag="IVD26_001556"
     CDS             complement(2858..3061)
                     /locus_tag="IVD26_001556"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079539.1"
                     /translation="MNLTKQEKRICRQIMLQIIGDRDMDELSQQESRMVRKISKLIIY
                     RDTERFLTVLGNVYENPELLEVE"
     gene            complement(3058..3909)
                     /locus_tag="IVD26_001557"
     CDS             complement(3058..3909)
                     /locus_tag="IVD26_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP6079540.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            complement(3924..4724)
                     /locus_tag="IVD26_001558"
     CDS             complement(3924..4724)
                     /locus_tag="IVD26_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP6079541.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            complement(4767..5657)
                     /locus_tag="IVD26_001559"
     CDS             complement(4767..5657)
                     /locus_tag="IVD26_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HAP6079542.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            complement(5659..6600)
                     /locus_tag="IVD26_001560"
     CDS             complement(5659..6600)
                     /locus_tag="IVD26_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAP6079543.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            complement(6833..7168)
                     /locus_tag="IVD26_001561"
     CDS             complement(6833..7168)
                     /locus_tag="IVD26_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079544.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            complement(7494..7682)
                     /locus_tag="IVD26_001562"
     CDS             complement(7494..7682)
                     /locus_tag="IVD26_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079545.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            7760..7984
                     /locus_tag="IVD26_001563"
     CDS             7760..7984
                     /locus_tag="IVD26_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004401476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAP6079546.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            complement(8276..8488)
                     /locus_tag="IVD26_001564"
     CDS             complement(8276..8488)
                     /locus_tag="IVD26_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079547.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            complement(8491..8703)
                     /locus_tag="IVD26_001565"
     CDS             complement(8491..8703)
                     /locus_tag="IVD26_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6079548.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            8978..9388
                     /locus_tag="IVD26_001566"
     CDS             8978..9388
                     /locus_tag="IVD26_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6079549.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            9401..9853
                     /locus_tag="IVD26_001567"
     CDS             9401..9853
                     /locus_tag="IVD26_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP6079550.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            10292..11224
                     /locus_tag="IVD26_001568"
     CDS             10292..11224
                     /locus_tag="IVD26_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAP6079551.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            11296..12417
                     /locus_tag="IVD26_001569"
     CDS             11296..12417
                     /locus_tag="IVD26_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6079552.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(12499..14271)
                     /locus_tag="IVD26_001570"
     CDS             complement(12499..14271)
                     /locus_tag="IVD26_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079553.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(14274..15986)
                     /locus_tag="IVD26_001571"
     CDS             complement(14274..15986)
                     /locus_tag="IVD26_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079554.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            16101..16769
                     /locus_tag="IVD26_001572"
     CDS             16101..16769
                     /locus_tag="IVD26_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAP6079555.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            complement(16836..17624)
                     /locus_tag="IVD26_001573"
     CDS             complement(16836..17624)
                     /locus_tag="IVD26_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAP6079556.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(17707..19179)
                     /locus_tag="IVD26_001574"
     CDS             complement(17707..19179)
                     /locus_tag="IVD26_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6079557.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            complement(19309..20502)
                     /locus_tag="IVD26_001575"
     CDS             complement(19309..20502)
                     /locus_tag="IVD26_001575"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAP6079558.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            complement(20768..20839)
                     /locus_tag="IVD26_001576"
     tRNA            complement(20768..20839)
                     /locus_tag="IVD26_001576"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20804..20806),aa:Glu,seq:ttc)
     gene            complement(20851..20924)
                     /locus_tag="IVD26_001577"
     tRNA            complement(20851..20924)
                     /locus_tag="IVD26_001577"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20888..20890),aa:Ile,seq:gat)
     gene            complement(20937..21007)
                     /locus_tag="IVD26_001578"
     tRNA            complement(20937..21007)
                     /locus_tag="IVD26_001578"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20973..20975),aa:Gly,seq:tcc)
     gene            complement(21012..21084)
                     /locus_tag="IVD26_001579"
     tRNA            complement(21012..21084)
                     /locus_tag="IVD26_001579"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21049..21051),aa:Phe,seq:gaa)
     gene            complement(21088..21160)
                     /locus_tag="IVD26_001580"
     tRNA            complement(21088..21160)
                     /locus_tag="IVD26_001580"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21125..21127),aa:Asp,seq:gtc)
     gene            complement(21179..21252)
                     /locus_tag="IVD26_001581"
     tRNA            complement(21179..21252)
                     /locus_tag="IVD26_001581"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21216..21218),aa:Met,seq:cat)
     gene            complement(21265..21354)
                     /locus_tag="IVD26_001582"
     tRNA            complement(21265..21354)
                     /locus_tag="IVD26_001582"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21316..21318),aa:Ser,seq:tga)
     gene            complement(21377..21448)
                     /locus_tag="IVD26_001583"
     tRNA            complement(21377..21448)
                     /locus_tag="IVD26_001583"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21413..21415),aa:Glu,seq:ttc)
     gene            complement(21470..21557)
                     /locus_tag="IVD26_001584"
     tRNA            complement(21470..21557)
                     /locus_tag="IVD26_001584"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21521..21523),aa:Ser,seq:gct)
     gene            complement(21582..21655)
                     /locus_tag="IVD26_001585"
     tRNA            complement(21582..21655)
                     /locus_tag="IVD26_001585"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21619..21621),aa:Ile,seq:gat)
     gene            complement(21669..21739)
                     /locus_tag="IVD26_001586"
     tRNA            complement(21669..21739)
                     /locus_tag="IVD26_001586"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21705..21707),aa:Gly,seq:tcc)
     gene            complement(21741..21816)
                     /locus_tag="IVD26_001587"
     tRNA            complement(21741..21816)
                     /locus_tag="IVD26_001587"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21781..21783),aa:Asp,seq:gtc)
     gene            complement(21835..21908)
                     /locus_tag="IVD26_001588"
     tRNA            complement(21835..21908)
                     /locus_tag="IVD26_001588"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21872..21874),aa:Met,seq:cat)
     gene            complement(21921..22010)
                     /locus_tag="IVD26_001589"
     tRNA            complement(21921..22010)
                     /locus_tag="IVD26_001589"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21972..21974),aa:Ser,seq:tga)
     gene            complement(22034..22107)
                     /locus_tag="IVD26_001590"
     tRNA            complement(22034..22107)
                     /locus_tag="IVD26_001590"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22071..22073),aa:Ile,seq:cat)
     gene            complement(22121..22194)
                     /locus_tag="IVD26_001591"
     tRNA            complement(22121..22194)
                     /locus_tag="IVD26_001591"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22158..22160),aa:Met,seq:cat)
     gene            complement(22222..22294)
                     /locus_tag="IVD26_001592"
     tRNA            complement(22222..22294)
                     /locus_tag="IVD26_001592"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22259..22261),aa:Ala,seq:tgc)
     gene            complement(22314..22387)
                     /locus_tag="IVD26_001593"
     tRNA            complement(22314..22387)
                     /locus_tag="IVD26_001593"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22351..22353),aa:Pro,seq:tgg)
BASE COUNT         6898 a         4625 c         3712 g         7159 t
ORIGIN      
        1 aattaaaaaa acaatagaca gcaacggatg atagataata agaacaattt agaaggagtt
       61 gaaattcaca tccttattct taatatttcc gttgctgcct atcgaagctt aattaaacga
      121 tgagggagat ttcctccctt acattttatt ttgtcgatcc tgtttcctaa tttttcgaca
      181 ctatcataat acaacgttga ataggtaagt gattggtata aaaaaggtat aaaatggaaa
      241 ccaaattggt aataaaaggg tataaaaagt gtaaaaactg gctacttgaa agcaaccagt
      301 tctaacgatg aagcaaattg gatgataatt ctgtttgatt ctactttaac cgattcttcg
      361 ctagtattat tcctttgagc agttacataa atgggcagac cattgatata acgatcatag
      421 aatatcttct tgcgcctttc agtcacatca ggcttatgcg gatgctgtat cgctgaatag
      481 cctcgaacaa acaatttatg cagatactca aattcttcct gtgcttcttc tttatcgatc
      541 agcattcttt ctgcttcaaa tatatgatca gctgtagaag gtggaaccaa ggaataagat
      601 gctgtcactt ttggttctcg atgttgccct actctacatc tagctgatag atatgctgaa
      661 agaaacacag cgacattatg ttttgtgcgt tccatatcaa catctttcgc gcttggtgtc
      721 tcatatttct ttacatcgaa aagtaccatc ctctgattcc cccaattatg atataatact
      781 tatgtcggaa atattattca tagtcggagg aatccgactt tttttatttt gtacgtgaaa
      841 tgagttctcc tgatttatac gcctcagcaa attcaaccaa agctactgcc ttcattctct
      901 cgatagttct atcggaatat cctaattttt ctcctatttg atacattgac atcttattag
      961 gaaaacaata actataataa agtacctgga aatggattct acttagccgt gttaatgctt
     1021 cgataaccga atctcgagta cttatcgctt caatgatttc ttcgttttga ctgtcaattg
     1081 tgaatttcaa atttttggta acagtcatca cggaaaagtc tattttcact ggtccgacca
     1141 aacgttctaa atttctgtat ctttttagta atcgtctagc atttttcctt gtttgcttaa
     1201 tatctatatt ctctaaaatg ttcacaattg cctcttctcc ttccagttgt ggaataacgc
     1261 tcattgttgt aggatagttg taaaaaagca aaattaagat tttataactt ccatgtccac
     1321 caatctcacc actgctaaat tctctttgct tttcgctaac cacttatcac attccatcgt
     1381 gttttcaatg cgaatgattg ctgagtgatt atagacgtgt tctacatatc cacgaaatgg
     1441 atagatgaat ccttctgctt cgcagcgaac catgtcaccg actttgaatt ttggtttctt
     1501 acgtgtttta ggattctttg tcggcatatc tagcattaaa ccgccgatgc cgtggccgct
     1561 ggagtaaaat ccgtctttta gtttcattcc gcttcctcct ctttagctgt caattactta
     1621 ctcgcaagtc actaaaatgg ctacttcatc gataaagttt ccgtcttcgt cttccattcc
     1681 ttgctgaatg ctaatgtcgg taatctgctt aaaaaattcg ttgtcatagc cttgtgcgtt
     1741 tatcactact tcgacgtctc cgaaaacctc tttgagacta ttaattttat ttactacttc
     1801 cgatgcgtcc atgactacac ccctttccag ttaaaaatct ctgtcgttaa tagactactg
     1861 ttcaaagtat tcatcttcac tcatccttct gcctcctctt tagttgtcat tagtggacta
     1921 aatactacct gtttgaaaac cataatgtgc agtttcaacg ccgtcataat cacttatttc
     1981 ccactcagcc ccatcgggta tatcaacgac tttaagactt gcatatggtc cactggcctc
     2041 acttcctagt ttttcgacaa cagcaacgag gtccttatca cctctgtttg aatcacttga
     2101 aaaactggaa tcatcagcaa ttccgtacag tcggtcaatt tcgctataaa ttcctgtaac
     2161 tttgtcgatt ttcgggtctt ttttgaaata gtagataaaa tccatcgaac ctagcttttg
     2221 gcctgtgtat ctcgtgtatt catcatctga gtcatagcta aagttattga tgtatgggaa
     2281 tacttcaata ttttttcttt taaaaatttc catttttgct tcatggctca acccaaagcc
     2341 accaaaacat ttatttaata caatcttcat tacttttcct cctttgtttc ctccgttagc
     2401 tgaatttttt cataaacaca agccaatgtg ttttgcttcg tttattacca aacaatggct
     2461 gttctccaat agcctctaac acatcagaaa gtggtatctg ttcctcgttc cacttaaaaa
     2521 ttaatgttcc tgaaggtcgt aaaactcgca tacactctgc aaaaccttgc ctgatgtctt
     2581 ctggccaaag ttcgtctaat tttccatatt ttttggcaag ccatgagttt tcgccgacat
     2641 gtcttaagtg tggcgggtca aatacaacca tatcgaacac atcatcttca aaaggcatat
     2701 cgcgaaagtc tgcgaccaca tctggatcaa cattgatcac atgacctgtt gataattctt
     2761 catactgctg acgacaatcc ataaatgtta cgtcagaatt gttcttatca aaccagaaca
     2821 atctactacc gcaacatgca tctaatattt ttggcaatta ctctacctcc aataactctg
     2881 gattctcgta gacgttacct aaaacagtga gaaatctttc tgtatcccga taaataatta
     2941 gcttacttat cttccgaacc attcgactct cttgttgaga taattcgtcc atgtcacgat
     3001 cacctataat ttgcaacatt atctgacgac agattctttt ttcttgttta gtcaaattca
     3061 tgcgatcgct cctttgactg gttttatgcg cttgtctgct gtttgagaaa ataccatcgt
     3121 aaatccatca gagttgacaa acattcttga tattgttctc gtaccgtaag cttttttcag
     3181 ttcttcacca agcaagttcg ttgtgataat cgttgctagg ttctgtcgtg catccaagaa
     3241 cgaatttagc gtgtttatgc caaacgctcg actatctgat gcatcttttc ctagttctga
     3301 accgatatca tcaatgatga ctaaatccgc tgttttgata tctgcaatca acgatccctc
     3361 aatcgttttt ctgagttcag gattgttgta cgaaaatttg atttgatcca gcatttcctg
     3421 taacccgata aataagattt ttttatcgta gtttgatcgc ttcaagactt cccaagccgc
     3481 tgccatcgct aggtgacttt tacctgttcc ttgttttcca gttaaaacaa ggtgacttgg
     3541 atttcctaac aagactgaat taacaaagcg tttggttact tcaaccgctt gtcttgtttc
     3601 ttgatcgaca atttgataat tctgcaatgt gcaatcaaac aacgcttgat taggcacaac
     3661 agaaccacct ttgaaaaaat tgattgctct tgctttcagg ctctcgttgt aaattcgttc
     3721 tgtttgtaag tcttcctgaa ctcgcaatgc tttataccca cattgcatac aggttggctt
     3781 acaacgttct gagccatcag ggttcttcgt acgccatcca tacaaaggct gtccgcattc
     3841 aggacattcg ccacgttgga caagcacttt ctgtatcagc ttttccatga tttccccaac
     3901 agtttccatg cctacgcctc ctctcaaata ggcaactcat ctgtgctaaa tttctcgtat
     3961 tcaagcgttt tagtttgttt tgttttataa tcacgatttg cttgcgctgc cattgtgtcg
     4021 tatttttctc gcaatttttt agcagataaa atattcgatg cccaaaacac attgtgctga
     4081 ctccattcaa tcattccccg tacctggttt tcggtccgct tgtcgatctc gatcattttc
     4141 cgaatgtcat ctgcccaact ttgcagattc ggctttttga tttcctgatt ctgacaaatc
     4201 tgtttgaata actcctccgc gagaatgtag taaactgagt cggtgtcgta aacacgcttt
     4261 ttgcgtggtt gcgacgatga tgttttatta ttcttttcat tcttataatt cttttcattc
     4321 ttgtttgtgt gcacttgttg ttcacttgtt gtgcgtttga tgttcatttg ttgttcactg
     4381 ctttggtaca aagaccagtt ttttattgat ataacgctgt atttcgtagt tgatttgatg
     4441 ttcaacattc cgtttttttc aaattgtttt agccatctcc atacagaacc gctgttcact
     4501 tgatgttcac gtttcacgcc ttcgttcatc tcagatgtga tagcatcgcg ccctgtgacg
     4561 aattctccgc tgttcacttg tatctctttt ccattaaaaa gtatcttgcg attctcatga
     4621 ctcgctttca tcaaacacaa gttccataat ttatacatat aaggattggt ccaaacgaat
     4681 gaattcatca cttttcgatg taatttgaca tatcctgtgt tcattcgtat ttctcctcta
     4741 gaaaagcaag ggagaaagct ccctcattat ttgtttaacg gcggattaga tgcatcaaat
     4801 aatccagttt gtacatcttc attttcttca gatataacct ctgcttcttt tctttcagga
     4861 atatcttctt caacttctgt ttcagcaata atgctgccgt cttcttgaac cctttggact
     4921 ctctcatccg atgtggtggc ttcttgcatt tcgatggaca agattcccca tttagaaaga
     4981 agatttctca aaacagtttt tcgtgccatt gcattgtaat cagatgccca cacaccactt
     5041 aactttgtct tatcgcgatc tttattgtta gcaatccgat gagcttcgat ttcttgtttg
     5101 gtccaataga cagttttttt gaatccattc agtaactcga aatagccaac atatccaatg
     5161 acttcatcag acgttctacc atttggatca aactcaaact cttctgtcag tcggttccag
     5221 ctttttagtt ctccttcgta aacttcgatc acatttaatg ctttgtattt acctgatcgt
     5281 tgggctaatt ggatatatcc tttatagcca agcatgaatt gagctttctt ttcccatttt
     5341 cctgtttgct tgtttttact attgaatgga actaaatatg cataacctaa attcttatct
     5401 agcccaagat ttaatgttgc agcagttaac gcaccactca tgatagacat cggttcacta
     5461 tctgcaagat aactgtcatt agatacaaga gtcataacat tcgacataaa agcattagca
     5521 ttgtcatgaa gcacctcttc gaacttcttt ctcattgttg gtgtattcat caaagcttta
     5581 agtcctaatt gacctggtgc aacttgtttc tgtggctttg ctgccaattg attttttaac
     5641 gattcatttg ttgccatatt atttgatctc cctttcggtt agccttcttg attcagtaac
     5701 gttataaatc tcttcatcat ttgcgacatc tggatatttc tctgctagtt tcttcgagtt
     5761 catacgtctc gtacggacaa atttccaact gatgatgttt ttttgagtga taccgatact
     5821 ggcttcacgt ttacctagct cgctgataat ctcgttgtct acttgacgga tagctgattc
     5881 aatttctttc ttagtccgtt tgagttcgtt tttctgttca actagttcat cgaaatgaat
     5941 tggtaacgtc gtttgaacgt cttcaacatc tgcatacttc tctttcaaga aatcagctgt
     6001 cgcttgacta ccatcaataa ttggctcgat acctccaaga acgtttgttt cccaaaactc
     6061 tactaattgt tcagtgattg tatcgatcag ctcttgatct cgttcaatcc gcttccagat
     6121 aaatttttga ccaccgatta agacagcgat gtaacaatag tctttgttta gaacgttcat
     6181 gtaatgttga acttgacaga gatagctaag cggtacctct tcgccttccc attctttacc
     6241 gagaaattga ttggctgttt tgcattccag aatggcattt tctcccacta cttcccgatc
     6301 aatatttgct cttaaaaatg gatgtaatgg atgttcaaat acttggtttc ttctgcgtac
     6361 ttttttgcct gtacgttcct gaaactcttt agcaaccact tcttctaaaa cattacccca
     6421 ataagcgggc tcacttcctg attcttcaag tactacttgt cctgtttttt ctagccatag
     6481 ttgataagga gatttccatt tattcaatcc taaaattgtt ccaacatccg aacctccgat
     6541 gcctttctta cggtcttcaa gccattcttg atggctcatt tctaaggtag atttactcat
     6601 cttcatcctc ctcatcaatt ggtgcttcat atggtggttt agcataatca ggatcagtta
     6661 aatagttgtc aagatttgct aactcgttca tgtttaacct cttttctgct tgctaacacg
     6721 caaagcacaa gcatggtaat tgcgaataac aagccaaaga ttacataact tttcgctaca
     6781 atcactaacg tgaaaaataa aataatgagt agatcaattg ttttttcatt catcattgaa
     6841 attccccctt gagaatacga gtcatcacat cagctaaatc ttccttgtta ttaataacaa
     6901 aagtatgatt tgaaggttga ttttcttctt catttttcgc ttgttcgtaa gcatccacag
     6961 caattctacg cataatatgt gctgacaatg ggagattttc atctaaatgt tcttcttgca
     7021 tagcaagaca aagtaaaatt tctgttgtct caccataaac gagactttta agttcccctt
     7081 ctttttgggc tgtacaaata atagaaacac cttgcttttg gcattcacgt ttcaattctt
     7141 cgataagatt ttcaattttc ttattcatgt gatataattc tcctagtttt ataaatttgt
     7201 atgtgactct ttgctggctg gcagagtcac ttttttattt gttgccatgc tttttgcttt
     7261 tcgatatgtt gcttgcttaa aataataggg cggctatttc cccaccgatt atcagcaatc
     7321 actttaccga tttttagcgc ttcttctcgt gccatagttg ctcctttctt ttgaatcaag
     7381 cagattgatt aaaaccatca atgctgcgaa caagcttccc ccgataatac tttggtgcgc
     7441 tacaatcact aataacccca aaatgaatcc tataaaaagt gtgtctgtct tcttcataat
     7501 ctaatctccc tattttttat ttctagcatt ctcaaatcct caagttcaga agcaattagt
     7561 tcagcttgcc tatctgatag ctcatcggct tttctaagcg ctgcacggtc atcttgtaat
     7621 tgtttcctgc gttgtttaat caaaccgaga atttgatgtt cttgttgcaa ggtatatgcc
     7681 atatcacttc tcctttcgtt tattgaattt ctccatttct atttgataaa atatttctat
     7741 agaaatggag gtgaaaacta tgggaaaaaa tcaacatgtt gtacctaatt ccaatggtgg
     7801 ttggaatgtc aaaggtgctg gaaattctaa agcgactgca catactaata caaaatcaga
     7861 agcagtaaaa atcgctagag agatttctaa aaatcaagga tctgagctat ttattcatgg
     7921 cagagatgga aaaattcaaa gccgtgatag tcacggaaac gatccacacc caccaaaagg
     7981 ttaatcatat ttaggagtta atcgaatacg ataaccgtca gcaggagttg catcggtcaa
     8041 tgtaacttct gctacttttt tcccttcttc tgtttcaata attaatcttg tgtaattgtt
     8101 ctcattcaaa atccctattt ttgattcttc cttcatgtca tccctccttc gtctctcgcc
     8161 gtcaccacct ccaagaagag gagttgccaa aatgaaaaaa cgtggacttt ggcaaacttg
     8221 aaaggagagc agcaactcct cttttcagaa gtggtgaatt tagatttttt agctattaac
     8281 aaacagctct aactctaaat cgatttttag aacgccatgt tctaaactgt tcatataaat
     8341 cgacatcaat tgttatttct ttggaagtaa ctgcgttata cccctcacta aaacgtgatt
     8401 ttttaaattc cttcattctt ctttgataag tactttcaga atacttatat ttctctttaa
     8461 actccgcttt gctcaaacgt tgtaccattt ttacgcctcc tgttctgatg gctgatcatt
     8521 agaatctact tctaacttga tatccaaaag ttcttcgatt tgttttaaac gttccttagg
     8581 ttttcttttt tcgatgaaga tatctcgtaa ataagtaatt gatataccca ttcgtcgagc
     8641 taactctctt tgactccaac ctttctttac taaagcaatt aatacttgct gttttaaagt
     8701 catgcttcat acccccttat cgaatatttt ctaatatttt tgtctaataa gtttgacaaa
     8761 aactgcaaat atgctattat gtaagcatac aaaatacagc gcacaaaaag cgagcttact
     8821 gatgtctggg gagactatta gtttattgct tttagtcttt gtatgccgta aatatcttgc
     8881 ttacaaaact agtataactg caaattctct atttgtaaat agataatttg cagaaaaata
     8941 ctttttttgt cggtattttg aaaggaatgc atatcctatg ctattagacc gtataaaaat
     9001 cttattaaaa gaacgttcaa tgacgttggc agaacttgaa agaaagttaa atttcggaaa
     9061 tggaagcatg tctagatgga ataaaagtac tccatctgga gataaaatac aaaaagttgc
     9121 agattacttt aatgtatcaa ctgattatct tttaggacgt actgataaac gccattatta
     9181 tgatttaaca gaaaaagata aacaagatat tgctttacaa gctgaaaaat tacttgaagg
     9241 cttgaattca gatgctgaaa caaattatta tggtgaacct ttagacgatg aagataagga
     9301 aaaattatac gatgccattc aacttgcact tgccttaacc aaagttaaag caaagaaaaa
     9361 attcactcct aaaaaatatc gtcaataggt gggctttggt atgcatttaa acaaatactg
     9421 gatattagaa gaaatagaaa aattatttgt agagtttgga tctgatgcga ttaatccata
     9481 taaaataatc aaatattctg atatagattt aattgaaact gatttaggga ataaaacatt
     9541 aggacaaacg atacacaata aaagatgtta tgtgatatta attaatcaaa acctatcacc
     9601 ttctatgaaa agatttgtat tatggcatga aatagcccac gttagactcc ataaaggtat
     9661 ttgcacagca gcttttagag caaacaacct tagttgtatg atttatggta tagaagctga
     9721 agctaatatg tttgcaattg aaatgttaac tagaacaata gatgaacaag atttatctga
     9781 tatgagtcag ttccaaatta ttgaatattt agggcttcct cataatcttg aacatttagt
     9841 attacaacat taaaaataaa aaagcccatg ctttcacatg gactctttcc tcatttctga
     9901 gtaaactcta caataattat atcaaagaaa tgaggagttt tgaatgttat tattgattgg
     9961 acttatttta ttaattatag gaatcactaa actgtcgaaa gctaacacaa taaaaaaaga
    10021 agcttatgaa ttagaacaaa aaaatgatga aaaactaaat aaattacatg atagagaaag
    10081 atttatatta agtaaggaag aaacactatc agatttaaat aaacaaatta ctatgttaaa
    10141 aaatgatatt attttattaa aaaaagagaa agaagattta aatgatgaaa taaatcaaaa
    10201 gtatgatgaa acattaaaaa atgtctattc ttcacttatc gtttcaaata tagaagaaac
    10261 ttcatcttct gaaataaaaa ataagctttc tttgttaaaa ttaaaagaaa aggaatatat
    10321 tattgacgat gctgtttctg tccctcttat tttaaataaa cgagagaaaa ataatttaaa
    10381 gaaaaaaatg ctcattccat ttgattcaga agtgaaagga ttactcaata aactaactat
    10441 ttctaatata gactcgacta gggaaaaaat cataaaaata tttgataaaa ttaataattt
    10501 attcaagaat gacaatgctg aattaaggaa gggtctttta gagtttaaac ttcaagaact
    10561 agaacttcat tactcttatt tagtgaaaat taccgaagaa aaagaacaac aaaaagcaat
    10621 aaaagaacag atgatagaag aggaaaaagt tcgtagagaa attgatcgtg aaaagaaacg
    10681 tattgataaa gaacaacgtc aattcaattc tgaaatttcc aaattaatcg catatatgca
    10741 aaaagctaat gcagatgtgg aaaaagaatt atatgcaaat aaaattcaag aactggaaga
    10801 aaaattaaaa gaattagaag ttatacgtga aaatgtatta caaagagaat taaatactag
    10861 agccggttat gtgtatgtaa ttagtaatat tgggtctttt ggtgaagaca tatataaaat
    10921 tggtatgact agaagattag aacctatgga tagaataaaa gaattgagta gtgcatcggt
    10981 tccatttgaa tttgacgttc atgcgatgat tttttcagag gacgctccgt ctttggaaac
    11041 taaattgcat aatcatttta gaaaacaaga agttaataaa attaatcaaa gaaaagaatt
    11101 tttcaaagtt tcactagacg aaatagagaa agttgtttta gaaaattata atggaacagt
    11161 aacatttaca aaattagcta aagctgaaca atatagacga tctttagaat tgtcaaaaga
    11221 ttaaatatat aaaaagcctt cgggcttttt cttttaacaa ttaataggaa cgtatattcg
    11281 aaaggaatag aaataatgtg gttagaaaaa ataaatgaca aaaaatttaa gtacaccgaa
    11341 cgttatacgg atcccttaac tgaaaaaaag agaaaagtgt ccgttacttt atctagcaat
    11401 tcacgccaag cttggaatca agctaactta cttttgaatg aaaaaatcgc agaaaaaata
    11461 aaacgaaatg aagaattacc actaactttt ggagaattaa aaactaaatg ggatgaaaaa
    11521 tacaagccaa ctgtaaaaga aagttcctat cgaacaactc aggtttatct atcattaatt
    11581 tcaaaatata taaaagatga tgtacttgta aaaaacgtta atagtaatct tatacaagat
    11641 atgctagatt actactattt tgaaaaaaat ttatcatata attatgtaat acatttaaaa
    11701 acttttacag gaatgatttt taaattcgcc aaccgtcgat atggattaaa atataatccc
    11761 gtaaatgggg tttctttagc aagaaaacct aagacaaacg aagaaataaa aaaagaaaaa
    11821 gatggttatt tatcaaaaga agaagttcaa atgattgcta gtaaacaaaa aagttcacat
    11881 caacagtcac gttattcttt aattactaaa tttttgtttt taactggact acgttatggt
    11941 gaattgatat ctttgactga atctgattat gatggtaata aaattacggt ttctggtact
    12001 tatgattacg agttaaaaat taaaacaaca actaaaaata caggttctta tagaaccatt
    12061 gaattatcaa gtaatgctaa agaaatcata gatcaattaa ttgaagaaaa caaattaatt
    12121 aagaataata aagataaata cattttcatc tctaaaaatg gtaacccgat atctattcaa
    12181 gcatataatc aatctttaag agcagtatcc aaagaattaa acctagataa aaaagtttct
    12241 tctcacatgt taaggcattc ccacatttct ctacttacag aattaggaat cccattaaaa
    12301 gccattatgg atcgtgtagg acatgaagat tcaaaaacaa cattaaagat ttatactcat
    12361 acaactaaaa atatgcaaaa tcaactagta gaaaaactag gaaaaataga aatttaaatt
    12421 gccccttttc tgccccttat aaaaacaaac aacataaaat atataaaaag aaccccgtta
    12481 taacgaggtt cttttaattt aactttcaaa tacaaattga ttatgataaa gttccgcata
    12541 aaatccattt tctgctaata actcatgatg actgccttct tcaatgactt ccccatcacg
    12601 caagacaacg attctatctg cattcaagat tgttttcagc cggtgagcaa tcacaaagct
    12661 ggttcttcct ttgattgctt catccattgc tttttggatc cttgcttctg ttaccgtgtc
    12721 tacattactt gttgcttcat ccaaaatcaa taaagatgga tttgtgatga tcgttcgagc
    12781 aatactgatc aactgctttt gacctgtact gaataagtta ttttcttcgg atatctctgt
    12841 atcataacct ttttctaacg tcatgatgaa gtcatgaata ttcgcttgtt ttgctgcatt
    12901 gatgacttct tcatctgaag cgtccggttt gccgaatgtg atattgtctt tgatcgttcc
    12961 ggagaacaat acagattctt gcaaaacgat tcctacatgt ctacgtaatg catcaagatc
    13021 ataatctcgg atatctattc catcgatgac tactgaacca tcattgacat cgtaaaaacg
    13081 gtttagcaga ttcatgatcg tcgttttccc cgatcctgtt ggaccaacaa gagcaaccat
    13141 ttctcctttg tccacattga tcgagacatc tttcaagact agtttttctg gagaataacc
    13201 aaaatctacg tgctgcaacg caagaccttt ttcaacacca tcaaatgctt taccgttttc
    13261 tggtttgact tcatcttttt catcaaatat ttcattcaat cgtcttgccc ctgtaatcgc
    13321 taattggatc atgctgtatc cagatgaaat ctgcatcagt ggttggtaat attgttgtga
    13381 atactggacg aatgtcacaa ctaagcctaa tgccaccgaa cgttccaaat caccatttaa
    13441 tgctaaccag ccgccgaaaa agataactat cgctgtattg accagtgaca ttccttgcat
    13501 catcggaaat agtagaccag aataagcttg tcctttgaag gttgcttcgc gaacactttg
    13561 attatgctct aagaatcctt caatcgtttc ttcttgtaag ccatttgtga tgatgacacg
    13621 ttgtccgctg attttttcat ccatataacc atttagtttc cccacttcat cttgctgaag
    13681 atccacatat ttccgtgctt tgcggataat caagacagct atcaaaacgg ctactggagt
    13741 ggaagcaatt gtagcccaag ctaactctac attttggcgg aacatcatga tcaagatccc
    13801 gacaagtaaa acagcattcg tgatgacttg aagcaaagct tggttcaaac tattttgaat
    13861 attatctaag tcactggtaa aacgacttaa aatttcaccg tcttgatgag aatcaaagaa
    13921 acggatcgtc aatttttcca atttgttgaa tagaccgata cgcattcggt tcgttgactt
    13981 ccctactact tgtgtgaaca aaatactata gataaagttg gctgcactag ctagtacata
    14041 aaacagcaag agtttccata ttacagaaac aaatttgctt ttatcgtcta cgccttgcat
    14101 caagcctcct acgtaattag ctaattcttg aaaagcttcc ccgatgtatt gaggtgcctt
    14161 tacttgtaga taggtagcaa tgatcactgt gataaagata aagaaaaagg agagtttgta
    14221 ccgcttcaaa tagtgataga aaaatttact tgcttttatt agatcagtca tacttactcc
    14281 tccgttcctt tttgagtttc aaagatttcc tgatagacac ggtttccagc taccaattcc
    14341 tcatgggttc cttcgccgac taatctgcct tcatccaata ctaagatgcg gtctgctttg
    14401 acaacagaag caattttttg tgcgatgaca atcgtcgttg ttcccttcaa atctcgatcg
    14461 agtgcttctc ggaccagctt ttcagagcga gcatccagtg cactcgtact gtcatctagg
    14521 atcaagatct ttggattacc gataacgcca cgagtaatgg ataaacgttg cttttgacca
    14581 ccagaaaagt tactgctacg ttcttctatt ggtgcttcgt aacgatcaga taacttttcg
    14641 atgaattctt ttgcttgagc aatagaagaa gcatgttcca tctctttttc tgttgcattc
    14701 tttttccctt ggcgcaagtt ttgagcaatc gttcctgaga ataaaattgc tttttgcaaa
    14761 acaaaggaaa ccgtttgtct taaactcttt tcatttactt gacgaagatc tacaccacct
    14821 acttcaactt tgccttctgt cggatcaaat agacgaggga tcaattgtgc tagtgttgac
    14881 ttcccggcac cagtcgcccc gacgatacca accatttctc caggtttgat agaaaagctg
    14941 atatctttaa gcgtatctgt atcctcacca ggataacgaa aagaaacatg gtcaaaagtg
    15001 acagaacccg tcaactcttg ttctggaacg tctaaataag taagatctgg ttcagcatct
    15061 aaaatttccg caatccgctt cagcgatacg gctgctcttg aagtcatcat catcatcatt
    15121 ccgccaataa tgattgccat cataatctgc atcaagtagt tcatgaatga agcaattcca
    15181 ccaattaacg taggatcatc tttaacaaga tcgctcacaa aaaagatcgc cccaaccaca
    15241 gccaaattgg cagccagcat gaaggacggg atcatcacag aaaataatgt accgactatg
    15301 atgttgtgtt ttgttaagtc ctcacttact ttgctgaatg acttcaattg gttttcttct
    15361 tgtacaaaag atttcactac acgaatccct agtaagtttt cttttgcaat gctattcaca
    15421 cgatcaatca gtttttgaat gatcatgaag tgcttgccca tccttgtaaa tgaaagtgcc
    15481 gtaatcagaa ataccgtaac gataagcgct acgatgatcc accataattg cggcatcgtg
    15541 atcatagcta aaatgaaggc accaataaat aagaatggaa ttcgaaaaag tgattgcaaa
    15601 gaaatcatca ctaaattttg gatttgcgtg atatcatttg ttagacgaac aacaagattt
    15661 ccagcagaga actgttcgat atttccaaat gaaaatgtct ggatctttcg aaatgcttct
    15721 tctcggatat ctgcacttac gccttgagct acttttgcag agaaaatcgt gttcgttaca
    15781 cctgcggcta atcctagcaa agccagactg atcaggtaaa taccaattgt tttcatttca
    15841 tcattatctt ctgtaataat agcttccaat acttgctgta gtaacttagg ttgccataat
    15901 gctgctgcaa ccatgactgc tacggacagc aaggaaataa aaacagatac tttatatttt
    15961 ttcgcatgtc gtaagattaa tttcattcgt tgattacacc cctttgttta aattgacagg
    16021 actaatttaa cactgtaaaa ttagaccgac taacaattta ccatgtttaa aaagataatg
    16081 caatacacga ggttgataaa atggaaataa agctttctca agcaatcatc attcaggccg
    16141 cctttgatat cctggctgaa acacaagctc tttcgcagct ttccatgcga aacatcgcaa
    16201 acagaattca tgttcaagca cctgctttat attggtattt caaaaacaaa caacagctct
    16261 tgcaaaaaat ggctgaaaca atggaagaag aattagcgct tccagatcca actttgcctt
    16321 ggaatgaaca gttgctgcag tatatggaaa attactatga cctttataca cgtttccctt
    16381 gtggggcaga attagaaatc aatactgtgc ccgcttttcc gagtcgatta gaacatttgg
    16441 agcaaatgat ccaattactt gttcgtgaag gattttcagt cacccaaagt catcaggcca
    16501 ttgcctctct ccacaattta ttgattggac agttaatgga tcagcagcat gaacagcagc
    16561 ttcgacaaaa aattatggac ggaaatgaat ttttgaaaga aacagttcta tttatgcgta
    16621 attatgtagt tgaaaatcaa ttagagggat ttaaagaaag tatgcagtcc catgcagaat
    16681 tgaatgaaaa agcactcttt ctaacgagtg cacaaaccta tattgaaggc ttatgccaac
    16741 aaaataaaag aagagaaaac gagcagtaaa aaagctccta tagagatcac tatgtttgtg
    16801 atctctatag gagctatctt tttaagactc tttttttatt tttcttccat tagccacgcc
    16861 aatgcacgtt gaatccattg gtcccagaag atccagttat gatcgccagg tccttgttca
    16921 aaggtgaccg ccaagccttg ttcctgcata gcagatacca tttcctgatt tgcctgataa
    16981 agaaaatcag attccccaca agccatataa aatcttggaa ctggttttcc gctttttact
    17041 agttctttca ataagtattg cggatcattt tttgaacctt cgatttgatc caatggtcca
    17101 aagatccctt cccaaaaaga tgctttacga accatcaaaa gatcatccat tcgatttcct
    17161 acagaaacag cgcctgaaag agagattact gctgcgaaat tttctgattt tgcaaggcct
    17221 agttttaacg cgccatatcc gcccatcgat aatccagcgg catatgtttt ttctcttttt
    17281 cttgttaatt gcgggaataa ttcatgacaa atctcaggta gctcttctgc aatgaatgtc
    17341 caatacttca tgtcataaac tgtatctgtg taccagccaa gatcagtaga tggcatgatg
    17401 acagctaatc cgtagtttgc tacataacgt tcaatcgacg tacgtctttc ccatacacta
    17461 tgattgccac ccattccatg aagtaaatat aaaacaggta tatccgttgt ctcttgctct
    17521 gaactggtgc caatcacctt ttttgttgtt tgcggtagta tcacatttag attgacttcc
    17581 atttctaaca cattcgaata aatatttgct tgaataaatg ccatattttc gccttcctta
    17641 gtaagaagtt atttttgaat aactttaaat ttgaatgatt cggctacgta catatcttaa
    17701 ccgaaactac tgttttattt taccactttt ttcatgaacg aaaagcgtta agaccaaagc
    17761 aatgatcacg agtaacaagc caactagata aacggaatgt aacccatcat aaagaatttt
    17821 tcttaatggt aacaaaatat ccgcatcaat atatttagcc gtttgtggat tcaccagttt
    17881 attcatgata tctgcatcat ttgttaaatt tgctgctgca agttctcgtt tagttacccc
    17941 atttatcaat aaaccaaaaa tagaaaccat gactgtttga ccaattgttc gaactaacgt
    18001 attaaaagaa gttgctacac caagctggtc acgagataca ctattttgtg cactgacagt
    18061 cgaggtagtc atggtcacac ctaagcctat accgatgacc gttgatatag caaaaaacca
    18121 taaatagtta cttctgaaag gcataagata caaccaagcg cccccaatag ctgcgattag
    18181 tagtccaatt ctcaagaccc aatgagtttt catttgagtc atccacttgc ttgcaaggaa
    18241 agaaccgacc atccagacta gtgataatgg tgctaatacc agcccaccaa ttgctgcatt
    18301 cagccctaat acaccttgca tccacatagg gatataaaca tcgattccca tcaaaaaacc
    18361 actagccaat gctgcagcca agttgaccac aacaaatagt ggatttttga ataaatgcat
    18421 catgatgaca ggatctttag ctcttttttc ggcaaaaaca aaaataccta acattacgat
    18481 actacctagc agcaaagcag aaacaagcgg actcattcct tcgtctccta ataattggaa
    18541 ccctaacagc aatgagacaa gcatggccat caaactaaaa ctaccaaaaa tatccattgg
    18601 tttagactca tgtatgattt ttggttcatt taaatatagc caaatcaaaa taattaatag
    18661 aattccgatc ggcacattga taaaaaagat ccagtgccag ctgatcgttt caacgatgaa
    18721 tcctcccgca agcggtccaa aaacactggc aatcccccag gctgaactat tcaaacctaa
    18781 aacttttgct cgcttttcaa tagaataaag atcgccgatg atcgtcaaag ctactggcat
    18841 cattgcccca gcacccatcc cttgaatcgc acgagcagca atcaacccaa tcatgctttg
    18901 agataaaccg caaaataacg aaccgataat aaacaataat gtcccaaaaa taaagattgg
    18961 tttccgtccc actttatccg caagttttcc gtaaatcgga gtaagcatag cgtttgtcag
    19021 caaataaatc gaaaataccc agttcatgat ttccattcca tgtaatgaac cgacaatcgt
    19081 tggcatagcg gttgttacga ttgtaccttc aatagccgtc atgaacgttg caatgaaaat
    19141 actcactgtg accaaagtaa catttgtttc ttttttcatc ttattcctcc ctttcattat
    19201 gacaggatct aaaaatagat aaataattac tatctttttc aagaggttaa ctgccataaa
    19261 aaaagctgga acaaccacca cttggcgatc gttccagctg aatataactt attttgctaa
    19321 acttgctttc aacgcatcta ctttgtccgt atgttcccaa ggcaaatcta catctgtacg
    19381 accaaaatga ccgtaagcag ctgtttgttt gtaaatcgga cgacgcaaat caagcatctc
    19441 gatgattcct gctggccgaa gatcgaagtt ttctctcact gcagcaatca gttcttcttc
    19501 cggaaccgtt ccagtaccga aagtattgat tgagatcgaa acaggttgag caacaccaat
    19561 cgcataagct agctgtactt ctgctttgcg agcaagccct gctgcaacaa tgtttttagc
    19621 aatataacgt gcagcatagc tggcagaacg gtcaactttt gtcgcatctt taccagaaaa
    19681 agcaccgcca ccatgacgag cataaccgcc atacgtatca acaatgattt ttcttcctgt
    19741 taatccggca tccccttgag gaccaccaat gacaaatcgg ccagtcggat tgatataata
    19801 tttcgtttga tcatctaata attcagctgg aataacttcc ttcactactt tttcgatgac
    19861 atcatgacga attgtttcat tatctactgc atcatcatgc tgtgttgaaa taacgattgt
    19921 atctacgcgt tccggttgtc cttgatcatc atattcaacc gttacttgag attttgcatc
    19981 tggacgtaaa tacgttaatt catttgattt acgcaaatct gccaagcgtc gtaccagacg
    20041 atgactcaaa gcgattggta aaggcatcaa ttctggtgtt tcatctacag caaacccaaa
    20101 cattaaacct tggtcaccag caccaatctc atctaatacg tcttttttat cttcatcccg
    20161 gatctcaagt gcttcatcaa ctccttgagc aatatcagga gattgttcat caatcgcaac
    20221 caatacagct gctgtatctc catcaaatcc gaattttgca cgtgtataac caatttcttt
    20281 tattgtttcc cgtacgactt tttgaatatc tacatatgcc gtcgtagata tttctccaaa
    20341 tactaaaaca agaccagttg ttacagacgt ttcacacgct actcgtgctg ttggatcttg
    20401 ttttaaaatt gcatccaaga ttgcatcact gatttggtca gcaattttat ctggatgtcc
    20461 ttcagaaaca gattctgatg taaataagtg tctttctacc attataatga ttccccctag
    20521 ttaaattcgg ttacaaggca tctccgtcct gcggatcctt tcgggaactt gcaacgaacc
    20581 aagtatagca gataaaacag ttttctgctc gtattttttc atttttttgc ttaaaaaata
    20641 taaaaatatt ttacattaga actgtccaaa aaagcttagc acaatcatcc ataaagataa
    20701 ctctgctaag ctttttaaaa tcattctttc agataaaaag aaaaagatac tcaaaaagta
    20761 tcttccatga cccgtacggg attcgaaccc gtgttaccgc cgtgaaaggg cggtgtctta
    20821 accgcttgac caacgggcca ataaaataaa tgggcctaaa tggactcgaa ccatcgacct
    20881 cacgcttatc aggcgtgcgc tctaaccagc tgagctatag gcccataaaa actaaaagcg
    20941 ggtgacgaga atcgaactcg cgacaacagc ttggaaggct gtggttttac cactaaacta
    21001 cacccgcata atggcgcggg acagaatcga actgccgaca catggagctt caatccattg
    21061 ctctaccaac tgagctaccg agccaaacgg ttccgacggg aatcgaaccc gcgatctcct
    21121 gcgtgacagg caggcatgtt aacccctaca ccacggaacc aatgttttta gtttttaatt
    21181 gcgggagcag gatttgaacc tacgaccttc gggttatgag cccgacgagc taccagactg
    21241 ctccatcccg cgataatatg aaaaaggagg ataagggatt cgaacccttg cacggtttta
    21301 cccgcctgac ggttttcaag accgttccct tcagccggac ttgggtaatc ctccatgtaa
    21361 aactatatta aattaatgac ccgtacggga ttcgaacccg tgttaccgcc gtgaaagggc
    21421 ggtgtcttaa ccgcttgacc aacgggccag gtaaaacaaa atattgaaac ggagaaggag
    21481 ggatttgaac cctcgcgccg gtttcccgac ctacaccctt agcaggggcg cctcttcagc
    21541 cacttgagta cttccccaaa accaataaga ttttgtacta atgggcctaa atggactcga
    21601 accatcgacc tcacgcttat caggcgtgcg ctctaaccag ctgagctata ggcccataaa
    21661 aaactaaaag cgggtgacga gaatcgaact cgcgacaaca gcttggaagg ctgtggtttt
    21721 accactaaac tacacccgca tggcggttcc gacgggaatc gaacccgcga tctcctgcgt
    21781 gacaggcagg catgttaacc cctacaccac ggaaccagtg tttttagttt ttaattgcgg
    21841 gagcaggatt tgaacctacg accttcgggt tatgagcccg acgagctacc agactgctcc
    21901 atcccgcgat aatatgaaaa aggaggataa gggattcgaa cccttgcacg gttttacccg
    21961 cctgacggtt ttcaagaccg ttcccttcag ccggacttgg gtaatcctcc atatgaaact
    22021 tacaacgcca caatggacct tgtaggactc gaacctacga ccggacggtt atgagccgtc
    22081 tgctctaacc aactgagcta aaggtccagg ctcttaaaaa tcgcggcgga ggggatcgaa
    22141 cccccgacct cccgggtatg aaccggacgc tctagccagc tgagctacac cgcgaaaaag
    22201 atattcatta tttaaatgaa atggagccta gcgggatcga accgctgacc tcctgcgtgc
    22261 aaagcaggcg ctctcccagc tgagctaagg ccccgtgttt aaatttataa ttatcgggaa
    22321 gacaggattc gaacctgcga ccccttggtc ccaaaccaag tgctctacca agctgagcta
    22381 cttcccgttt aatt
//
LOCUS       DACBYO010000043        22127 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.043, whole genome shotgun sequence.
ACCESSION   DACBYO010000043 DACBYO010000000
VERSION     DACBYO010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.043"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..312)
                     /locus_tag="IVD26_001594"
     CDS             complement(<1..312)
                     /locus_tag="IVD26_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP6079559.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KF"
     gene            complement(531..1010)
                     /locus_tag="IVD26_001595"
     CDS             complement(531..1010)
                     /locus_tag="IVD26_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAP6079560.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(1137..2816)
                     /locus_tag="IVD26_001596"
     CDS             complement(1137..2816)
                     /locus_tag="IVD26_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAP6079561.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            3364..4866
                     /locus_tag="IVD26_001597"
     CDS             3364..4866
                     /locus_tag="IVD26_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079562.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            4879..5541
                     /locus_tag="IVD26_001598"
     CDS             4879..5541
                     /locus_tag="IVD26_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079563.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(5642..5845)
                     /locus_tag="IVD26_001599"
     CDS             complement(5642..5845)
                     /locus_tag="IVD26_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP6079564.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(5956..7140)
                     /gene="iadA"
                     /locus_tag="IVD26_001600"
     CDS             complement(5956..7140)
                     /gene="iadA"
                     /locus_tag="IVD26_001600"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAP6079565.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(7297..9036)
                     /gene="yfcC"
                     /locus_tag="IVD26_001601"
     CDS             complement(7297..9036)
                     /gene="yfcC"
                     /locus_tag="IVD26_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAP6079566.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(9809..10423)
                     /locus_tag="IVD26_001602"
     CDS             complement(9809..10423)
                     /locus_tag="IVD26_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6079567.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(11029..11406)
                     /locus_tag="IVD26_001603"
     CDS             complement(11029..11406)
                     /locus_tag="IVD26_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079568.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(11706..12587)
                     /gene="galU"
                     /locus_tag="IVD26_001604"
     CDS             complement(11706..12587)
                     /gene="galU"
                     /locus_tag="IVD26_001604"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP6079569.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(12630..13649)
                     /locus_tag="IVD26_001605"
     CDS             complement(12630..13649)
                     /locus_tag="IVD26_001605"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP6079570.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(14282..15286)
                     /locus_tag="IVD26_001606"
     CDS             complement(14282..15286)
                     /locus_tag="IVD26_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6079571.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(15299..16348)
                     /locus_tag="IVD26_001607"
     CDS             complement(15299..16348)
                     /locus_tag="IVD26_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6079572.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(16365..17186)
                     /locus_tag="IVD26_001608"
     CDS             complement(16365..17186)
                     /locus_tag="IVD26_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP6079573.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(17173..17952)
                     /locus_tag="IVD26_001609"
     CDS             complement(17173..17952)
                     /locus_tag="IVD26_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6079574.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(17969..18439)
                     /locus_tag="IVD26_001610"
     CDS             complement(17969..18439)
                     /locus_tag="IVD26_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6079575.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(18451..18870)
                     /locus_tag="IVD26_001611"
     CDS             complement(18451..18870)
                     /locus_tag="IVD26_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAP6079576.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(18951..21719)
                     /locus_tag="IVD26_001612"
     CDS             complement(18951..21719)
                     /locus_tag="IVD26_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6079577.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            21919..>22127
                     /locus_tag="IVD26_001613"
     CDS             21919..>22127
                     /locus_tag="IVD26_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079578.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKS"
BASE COUNT         6499 a         4657 c         3705 g         7266 t
ORIGIN      
        1 gaattttacc acgccgaatg gaaacgcatg ttttccaccg atattcatac cgaatgaatc
       61 tactcctctg ctgttcgcat aatcagcaat ctcaacaata ctgataattg tggcttgatt
      121 ttcttttgca ataggaatca tatctcctat gtggtcacta tgaccatgag taatcagcaa
      181 ccaatctgtc tttacttctt ctgcagttaa gtctgtcaat ggatttcctg taataaacgg
      241 gtcaatcatc acgcgttggc cattttccat ttcaattgtt aaacaggaat gtccatgata
      301 cgtaattttc atattttaca cctcgcgttt tctctgtatc ttttttatta aaaacgattt
      361 catcacttgc acatcaatga aaaaatatag ctgctaaata tattttcatt ggattgatag
      421 tacagtatgt acaaagcaat tgtaacagat aatacaggat gcaccaagta ccaagcagat
      481 ataatctcaa gtttgaggtc tctgctctgc ttagcttctc ttctcgtccc ttaactaatt
      541 aaatcagcgt aaataggatg gacgatcttt tctaaatcgg ctacttttat ccgaaggctt
      601 ctcccgattt caccgcttga cacaattact tcttcttttt cttttaaaga actgtctgct
      661 aaaaaacaat aatcaggatg tgcgagtttt attccaatag gggtgtttgc tccgtgggga
      721 tatcctgtat gcattaatac aaaatccatt ccaggaaaac caactttacg atctttcgtc
      781 acttgtctcg tttttttgta atctaagtga tcgttcaaag gaatcaatgc gatgatcacc
      841 ccagttttgt ttcctttcac tacgagagtt ttacatatca aagctggatc aatccctctt
      901 ttttgtagtt cttctgtgaa agattcttct accacatgac taaaatcaag tggttgatag
      961 ctgatctttt gttcttctaa ataacgttcg acttttgttt gactcatcat tgattcactc
     1021 cctttattct atcgtttatt ataaagcgag ggatgctgta ttcaaaaatt atttgttttt
     1081 cgcaaaaaaa gagcaagacg agcactctat agagaggttc atcttactct ttttgtttat
     1141 tttttatttc gacgttgagt agcttccata atgactggca agatcactgg gcggcgtttt
     1201 gtttgttcaa ataagtaacg gcctaattga tctcggatgt cttgctttaa tttgctccac
     1261 tcaaaatcat tgctttctaa atgtttctca acgattgttt caatcatatt gctgctttct
     1321 ttcatcagat cacggctagc ttttacgtaa acgaatcccc gtgaagtaat ttgaggtttt
     1381 gaaatgattt tcttttctcg ccgactgata gtgacaaccg ctacgaaaat cccgtcttct
     1441 gacaagattt ttcgatcacg taaaacaatg tttccgatat cacctatgcc taatccatca
     1501 atcattacat tttctgcact tgtagttcct gcaacactca tacgcttgtt cttatattcc
     1561 agcacgtctc cgcgtccagt aatatagata tttttgtatg gcatccctac tgcatgagcc
     1621 aaatctgcat gagcagctaa ttcacgatac tctccttgaa ctggcacaaa atatgttggt
     1681 ttcatcaaat tgatcattaa ttgcaagtca ttaggattgg catggccaga aacgcgcata
     1741 ttctcagaga tcaacttcac tgttccacca gctcgataaa tgatatcttc cgttttcgcc
     1801 acgatggttt ccatcgcgat gcttggcgta gtagtgatat aaaccaaatc tccttcttca
     1861 atcttgacat tacggtgtgt accgtttgcc attttttgca gagacttgat gggttcaccc
     1921 attcggccag tttctaaaat gatcagttct tctggatcat agtttttcat gtctttcaac
     1981 gtaacaagca gatcttcact tggtaattga agtttttcta aacgcatcgc tgtgcgaata
     2041 attcgttcga aatcttgacc agtcaagaca acttttcgtt gtgctttttc tgctgcatcc
     2101 aatacttgtt gcactcgttg caaattactt gctacacaag cgacgatgat acgcccttcc
     2161 caatatttga tcgtatcaaa tacttcatct gctatttggg cttcagaagc tacaggctga
     2221 ggattttctg catttgccga ttcacttagt aaggctaaga ctccttcttt gccgatttcc
     2281 gccaatcgtg cataatctgt ttgatacatt gggatagccg tttggtcaaa tttaaaatct
     2341 cccgtataaa cgatactacc ttcttttgtt ttcagattga tccccactga atctggtatc
     2401 gtatgagtgg tacggaaaaa gctcactact gtttcaccaa agtctatttc tgtatgctca
     2461 tctaccacat ggaaatcctt aaatcctttg gctgcttcat tacgactgac attcaatttt
     2521 gctaactcga tcgtcaactc tgtcccgaat actggtacag aaatttttga caacaagtaa
     2581 ggaagtgccc cgatcgcatc tgcatgtcca tgtgttaaaa agacaccagc tacacgatca
     2641 atgttttctt ctaaatacgt aaaatcaggg attacgacgt cgatccccaa caactcattt
     2701 tcaggatatt ttagcccaca atctaaaata aaaatatcct cgcccacttc tgcgacatac
     2761 atgttttttc cattttcacg aacgccgcct aatgggataa ttttaatggt actcacaaac
     2821 ttcacctctt cttatgacat ccaagtttaa agatgtcgat tttcttcttt atctaaatat
     2881 atgagccatt ccaatgaagc atatgcaaaa tcactatttc tcaacttatg gagaatcagc
     2941 aggaaaatta ccagcacatc cgcgttctga cagttggatg ggcattttat tttggatata
     3001 cttcattaac aaaatggatc ttttgcgaaa cgctatagcc agaatactta tataagtatt
     3061 cagctgttcc ccattattat acaacaaata aactaaatcg ctagtatcag caattgttag
     3121 aacaactatg cacgtaaaaa tccctctgta gcatctagga tttcttttgc tattcctctt
     3181 tcatttcttc ttcgtcggtt tgaaacatac ttttttcatt ttaccacatt ttttgcaata
     3241 actatagtga ctttttatat atacagaacc tcatgttgat ggtgtgcaaa cagcataaga
     3301 tttaagctag ctttaagata ggttgtctat tatcaaatgc atctactagg agggatgcaa
     3361 aatatgaatt ttatgaaacg tgcatggaaa agtacaaaag taaaatgggg acgttcattg
     3421 ttattgtttg ccgtgttcac agccattctt atttttgtgc tagctggcct cacgattcga
     3481 agcgctgcag aagaagcagc gaatcaagca caaaaagaag ttggagcaac agtgacttta
     3541 agtgccaatc gagaagcttc atttaaaaaa caggaacaaa cttcttcaag cggttctacc
     3601 actgaagaac gtccagatcc aggcagtttt tctcttacac cagtttcctt aacggacgcg
     3661 gaaaaaatag ctgaattaga taatgtaaag agttattcct ttgaaagttc cgcctcagct
     3721 atggcaaaag atggaataac tgccatcact agttctgatt caagtgaaga cagttcagaa
     3781 actactgatg caggcggtga acctgctgga ggaatgggcg ggaatccgca aatgactcaa
     3841 gcagactttc aaatcagtgg tgtgtcagca actgcacaaa atagtaattt ttctgatgga
     3901 acagcaaaaa tcacggatgg tgaaggaata gatgacagcg acaaaggcac aaacaatgta
     3961 gtcattgatt ctactctagc agaaacaaat gacctggcag tcggagatac tttcacaatc
     4021 acgagtactg aagatgaaga taccacttat gaaatgacga tcaaaggaat ttatgaatcc
     4081 agcgaaacaa gcggcagtat gggtatgaaa ttcaacttca tgaatccgtc gaatacactt
     4141 tacacttctt acacttttgc aaatgaacta aatgggacat ctgacgataa cacgatagat
     4201 tctgctattt acactctatc tgatccagat aaaatggatg agtttctcaa agaagctgag
     4261 aagctgatcg acacagatac atttagctta caatcaaatg attccatgta tcagtcaatg
     4321 ttggaacctt taaacaacgt ggcaagtttt tctaaaaatg ttgttttact agtggctgta
     4381 gccggtatta tcatacttac tctgatcatt atgattacca ttcgggagcg tcggcatgag
     4441 ttaggcgtct tgctatcttt aggagaatcc agaagtaaaa tcattctcca attgtttacc
     4501 gaagtggcta tttgtatgat tcttgcatta ggagttgctt cgcttagcgg aaacgtcgtc
     4561 gcgaatgccg tgggacagca gctacttgac caacagacag aaaccacgac acaaaaccag
     4621 caagctcctg gcggtggaca aatgccaggt aacagacaag aacaaggcgg tcaacgcgat
     4681 ggtcaacaag gaaccacgaa taatccattt gctgtttctg atcaagtcag cgaattggaa
     4741 atcaatgtca aacctgcaca attgggacta ttagccggag tagcatttgg aatcagtctg
     4801 ttttctgtct ttttagcttc tatagggata ttaagattaa acccaagaaa aatcctatta
     4861 aactaaagga ggaatttgat gttacggaca gaacaattgg gattttggta tcaagatccg
     4921 caagatgcgc tttataaaga tgtagaactg aatttcgaag ctggaaaaat gtacgctatt
     4981 ttaggagcaa gtggttctgg aaaaacgact tttctttcgc ttatttctgg actagatgca
     5041 ccaaaagaag gaaaggtata ctatcaagat cgttcactga acaaaatcgg gttaagaagt
     5101 tatcgtaaaa atgatgtctc gattattttc caagcttaca acttgcttcc ttatttatcg
     5161 gctctagaca acgtcatagc agcaatggaa atcactaaga ccaagcaaga gaattatcga
     5221 caagttgctt tagatcgact ggctcgtgta ggaattgatg aaatattagc aaaaaaacag
     5281 gtgaccaaac tttcgggagg tcagcagcag cgagtcgcta tcgttcgtgc tatctgctgt
     5341 gaacatcaac taatcgtagc ggatgagcct actggaaatc tagatgaaac aacttcacaa
     5401 gatatcgtca aacttttcca agaaatcgcc catgaacaaa atcgctgtat tatcatcgtg
     5461 actcatgaga ttgaagtagc aaaaagctgt gatgaagtct ttgaactaaa aaataaaaaa
     5521 tttcaaaaaa tcgaagttta aaaaacagga taatgatcaa ataaaaaatc cgaaccatat
     5581 ctgtctcgca gatatggttc ggatttttta tttgcttgat tcaattagta ataagtggtt
     5641 tttatttttt ttcgtctttt cgagaaaact tgtctttgac ttcgtcgcct aaatttcgag
     5701 ctttttcttt gatgtcagca cctagtgatt gtgctttccc ttctgtttct ttgctcttgt
     5761 cgtctgttgc tttgccgtat gcttcttttc cttcaccgac tactttatct ttcatatctt
     5821 tagaacgtcc ttttaaatct gccattgtgc ttcctcctct tagtttgttt attgatctac
     5881 cttcagggta acatcaacaa cagatacaga caaacagaac gctcgttttc taaaaaagat
     5941 agttagagct gttgattaaa aacttttttc gaaagtcccc catactttga cttctttttc
     6001 ttggaccatt atttctcctt tagcgataac tgtatcaata tcaagcgttt ctttatccaa
     6061 gatacacaga tctgcatcag caccaatttc gatttttcct tttttatcca atttcaatat
     6121 acgtgctgga ttactggtta tagctcgtaa ggcgatttcc aaagggatac tttctttttg
     6181 cacagcttct ttgatcccta ctagcaatgc cttggcactt cctactccta accctaggaa
     6241 atgattgttt tcatcaaaat aaggcaagct tccttgtcca tctgaggtca tcgtgaaatt
     6301 atctaaagaa acatcttcct cgatcaatcg tttcagtgct ttgctgaagc gaacttcacc
     6361 atctgtcttc tcccaaaaat caggatcttc gctagcagtg aagtcaatcg tgccaccacg
     6421 tttggcaaat gccacgcaag cttcaaataa ttctggtgtg cgatttgcat gagtaggcaa
     6481 aaattgtgtg atcggaattt ctgtttcttc tacgattcgt gtcaatagct ctagctttct
     6541 ttttcctccg cctaagtgga cattgatgat cccagctttt ccggataaca tgcctcctac
     6601 acgagcatct gctactgcac gagcgaactc ttcaaaactt ggctgagaag aacggtgatc
     6661 ggatactgcg atttctccga ttccgataat tttatcaatt gtcaaaaagt ctttgatgat
     6721 agaatctgtt actgttttta ccggcaatcg gtacgaacct tcgtatacat aagtggagat
     6781 tccttctgct tccagacctt tcgctttgct gatcaacgca gtcatatctc taccttctcc
     6841 gtctgttccc aaacaaccga caactgtcgt tacaccagct gtagtcaatt ggctcaatgt
     6901 gacttctggc gttcgatttt gataaccgcc ttctcctcct ccacctaaaa tatggaaatg
     6961 acagtcaatg aaacccgggg ttagtacttt tccctcacct gaaagttctt ctacttccac
     7021 tccttcgtag ccgccttcta gctgttcttc tacagccaaa atcttcccac cggcaatcag
     7081 tacatccatt tttcctaagt aatctggtgc aaacacttca atttgtcgaa tgattttcat
     7141 acatttttcc tctttcttta agtataactg atgataggat cttaaaaaat aatccaaacg
     7201 ataggatctt tactcctttg attttaccgt aaaatgacgg ttcttggagt ccttatctac
     7261 tgtttggatt acttttttat ttacaggtct ccagtactac tgcagaccta ttgcaatggc
     7321 aatcatgatg aaaatagttc ctaaaacaaa caggaatcct tgcatcttga tttggaatct
     7381 tgcccatttt gcccattcga tccgtgcaac acctagcaca ccaatcaagc tggctgatac
     7441 gggtgtaaaa gcgtccataa aacctgaacc aagctgataa gcaagaactg ctacttgtct
     7501 ggatacacct actaaatctg ccagtggagc catgattggc atagtcaaag ctgcttgtcc
     7561 tgaatttgat gtaacaacca agttgaacaa actttggaag atgtacatcg cccaagcacc
     7621 aatgacagct ggaacaccgg tcaacgccgt cccgatccca tgcaaaatcg tattcaaagc
     7681 tgaaggaaca gatgcatcag atcctcccaa gacaagaaga atccctttgg ccatacctac
     7741 tacgattgct gtaccagcta aatcagctgc accagattgg aaagaagaag cgatgtcatt
     7801 gactttcatt ccatctaatt tgaaaagaac agcaatgatt ccagcaacta atcccatcac
     7861 aaagaattga gaagcgattt ctggaatgta atagcctttt tgagtcacgc cccaaacgat
     7921 ccagacaagg acaactaaca tctctaataa gatcaattta tgcccaagca tgaatttttt
     7981 attttcatca gatgtctttt tgatatgaga acggaaataa tcatctgatt tgtaagtcaa
     8041 cgaactttct ggttttttac ggattttttc tgcatatatc atcatataac cagcggctaa
     8101 tgcagtaaca actacccaca taatcaatcg gaatgtcgca ccagacaaca cggggattcc
     8161 agcaatccct tgagccaccg ctacgctaaa cgggctcatc caagaggtcg catttccgac
     8221 ttgagatgcg acataagtca cggttactgc tacgatcgag tcatatccta acgcaatgac
     8281 aaatggaacc atcaccattg agaatggaat tacctcttct gccatcccga atgtagcgcc
     8341 accgaatgaa aaagcaaaga ataatagcgg taaagctaaa cgctccagtc ccttagtttt
     8401 actgataaac gcatagatac ctgcgtcgat cgctccggta cgcataataa taccaaaagc
     8461 acctccaaca acaaggatca atgcagcgat ccctacagca gatccatact tatctccaga
     8521 tactagtcct tcaaaaacaa aatttaagaa accaaagccg ccaaaatcat ctgttcccca
     8581 tattttggct gttttatgca attttttaga agtatcatag atattttcgc cgtactgatc
     8641 gtaaagcaca tcatctgtca aggagatttc atctagtttt tcctgcgtaa gatttttttc
     8701 tccgtcagca atgacttttt ccaatccttt ttccggaaca tccagttttt cacgttctgc
     8761 tggatgatct tgcagttctt ctaattgatc aaacacatac gacttatcca gctcgtaagc
     8821 ataacggaag gaatcttgac gtaaaacagt acgagtactt gtttcgccat ttgcatcttt
     8881 gtattcaata tcttgcgtgc tgaactttcc tgctggaacg acaaaagtca gtatccatgc
     8941 aaagatgact acaccaaaaa taatgacata cgtatggggt gtcgataatt tagtgaagtc
     9001 gcgtttcggt tttcctgaag aatttgtttt cttcaaattt atttcttcct ttcttttttc
     9061 agtaattttg atgaataaaa aatggataat caaatgaatt atacagtaaa aatgacattt
     9121 ccacatgaat aatttattag aaaatcactt ttttctattt tgtttttttt ctcctatgta
     9181 tgattatttt tttctctttc catttatatt aagtatttta tttctctgtt tttccttaaa
     9241 attctttttt tatttttaga ttagagaaaa tctcgtcctg tttttttcat tttacaatca
     9301 ttgaaaaatt gaatttcatt gcaaaaaaaa taataaacac ttataaatat ccattatcta
     9361 tccttcaatt tttgtgtatt ttatttctat tagaaaaagg tatcctgttg gacaattttg
     9421 ttatatcagg taaacttcat tgcaataatg ataacaaatg tactataatt actttgtaaa
     9481 gagttttggg gaagactctt tcatcaacgt gtattaagag acaagaaaga atccatatgg
     9541 attctttctt gtctcttttt ccactacttt ttatttttct gacactacat attcttataa
     9601 ctcatttctc ataactgtga aacaacttat aaaaataaca aactttaaac aaaacaagct
     9661 taaaatcaaa gatgatccat cttaaaataa ctaaaacaaa aaaagtagtc gttgttaatc
     9721 ctcattaata atcgttttct ttttttcaaa cgctccattt ttatgtggaa cattattttt
     9781 ttaaggaact ttgtcaacat gtggataact attttccact tgtgtcctgg actagctgtt
     9841 ttgctgtaaa atacaaaact tgctgcagca aaaagatcgt tgcaagagag gctgttccgc
     9901 agatcgctgg atctagattt ggcaaagtca agactgcatc atgtaaattg gcgtggttgt
     9961 ccaaaaccaa atcagcaaat tcaaataatc gcaaaccact gctatgttgc gatttgatac
    10021 ttcgtgacaa atcaaatcca gtaacaatga ttaatggatg accattttct ttgatccact
    10081 gagctagttc gatgattgcc gggtttcttc cttcattcga aagaagaaga aaaatgtctt
    10141 ctgatttgac agaaagctga tcaataattg cctgtcctgc accttctagc gtttcataga
    10201 cacctccggc tggattttca atcaatatac ttggtacaag atccggggtt tgatcccaaa
    10261 attcaaatgc tacaccactt agtgtgcggc tagcatatat ctgcaatcta ccaccttgat
    10321 taatttgttt cgcgatccaa gtgccagctt gaagcatcag cggctcttct atccttaatt
    10381 tctcttccaa ttggtgataa tagtcaaaat aacataaact catttatctc tcccgcctag
    10441 ctatacttga catgaataga aacagctgcc taatctaagg aagtacataa aaaaacagta
    10501 gttagacagt aacacatgtg gtctttgctg tttcaaacac aaaaaaggca ttgaacgaat
    10561 acgcccaata ccttgacata gcaaataaaa caacgtgcag accatggaaa atatctacat
    10621 aggggtagaa ttttcaccct agattaggta caataaatta ggtcgatgca ctgcattgac
    10681 tatggcaaaa tgatcggtca gggtgtatgt gtgtgactgg tcattccctg attcttagcg
    10741 ccaactaagg gtcagggagc ctttttttat tcagctgttt ctatctgaat ttattgtaag
    10801 taatctctta tccaagtgca agcaagaaaa tacaaaaaaa cattggtatg atttatatat
    10861 atataaataa cataaaaaaa ggaatggctt atcccgatac aacaagcatt cctttaaaaa
    10921 agattctttt atataagtga aaaaagcttt tttccaccaa ttaaataaat ctctcatctc
    10981 aatagtttat ccattatttt atcttttttt gcgtatacct actaaatatt accgtcttct
    11041 tctcgttctt ctactttgtt cgagagaatc tgtactagaa aaagtagttg tatgtctacc
    11101 ttttctgcct atccgagact ttcttttcat atatgggata taaatgatta gatacagtac
    11161 agcaaaaaat aaagcaaata cgcaagcttc ccaactacct aacgccaatt caaccatcaa
    11221 ggtagcaacc ccaacggatg ctgcatacca gataaaaatc agaaacgttt ctttttttct
    11281 gaccatgcga aacatgataa atagactaat aagcaatagt ggcaacacaa atatccaatt
    11341 gcttccttcc atcagccact tgagtatatc aagcagcgac tgtgcaacag cgactaattt
    11401 tcccatagtg aacacacacc tttttttata attaaaaaat tcgccttttt attctactat
    11461 gaatcttctg gcttggcttt catttctctt atgtaatcat tttcttttat acaacttaaa
    11521 aaaaaattaa accattagca taatattttc tgaatctatt cacgaaagtc tttttctatc
    11581 tttcgttttc cacgactcaa ctgatctaga gtcaaaaaac taaaacgaca gttgcgcaaa
    11641 tgacgcacaa gctgccgctt taataacaaa tagcctttca ttctcagcag gccacttatt
    11701 tccagttaac tttctgttct tagcttttta ctcaactgga taatatatgc acttaatgaa
    11761 gtcccaattt ccgaatgttg aagtccatat tcaatatttg tcttcatata tcctaactta
    11821 tcgcctacgt cgtatctttt tcctttaaac tctctcgcat agaccgcctc tgtctggtta
    11881 agagtctgaa gtgcatccgt tagctgtatc tcgtttcctg ctcctggttc ttgagtttct
    11941 aatatctcaa atattttagg agtcagtaga taacgtccga taatggctaa attacttggt
    12001 gcttttccca tttcaggttt ttctacaaac ccttttactc tgcaacgacc cttttcgcta
    12061 tctgttttag gatcaataat tccgtattta gatgtttcat tttctggtac acgcatgacg
    12121 gcaacagcgg aagcttgtgt ttcttcataa tccatcatca attgttgagt caatgggata
    12181 tcatctttca tcaaatcatc ccccagcatg acgacaaacg gttcatttcc tataaatgct
    12241 tttgcttgaa gcacggcatc ccccagtcct cttggatgag attgacggat gaagtgaaga
    12301 ttgacttgag tcgtttcttc aactaaagcg agtaattctg ttttttcctt ttcccgcaaa
    12361 ttgttttcca attcgatatt tgcatcaaag tgatcttcaa tgggtctttt ttcttttccc
    12421 gttacgatca agatgtcttc gattcccgaa tccaatgctt cttccacaat aaactggatc
    12481 gttggtttat ccacgattgg aagcatttct tttgccatgg cttttgttgc cggcaaaaaa
    12541 cgtgttccta gcccagcggc aggaatgact gcttttttga ccttcacttg ctgttcctcc
    12601 taaacgacga ttaactattg atcatctatt taacgaagag aaaattcatt ctccattttt
    12661 ccgtcacgta acatgatttc ttttgctgct tttttgatat cttctccatt atacaaaaca
    12721 ttatagattg tttgagtaat tggcatctca acacctagct gttgagctag ctctactgct
    12781 gcttttgtcg ttgccacacc ctcaacgacc attcccatgt tttctagaac ttcttccagc
    12841 ttatgtccct gtcctaacaa gttaccggca cgccaattgc gagaatgaac acttgtacaa
    12901 gtaacgatca agtcccccac accactcaaa ccgataaatg tcagaggatt ggcacccatc
    12961 gcgacaccaa gacggctgat ttctgccaat cctcgagtca tgattgctgc ttttgcatca
    13021 tctccgaatc ctaatccatg gatagcgccg gcaccaattg caatgatatt tttcagtgct
    13081 gcaccagttt ctacgccaat cacatcatta tttgtataaa tcctgaaata atcattcatg
    13141 aacagttttt gtacataggc tgctgctttt tgatcaatac ttgcagctgt aattgttgtg
    13201 atatcatgta ctgccacttc ctcagcatgg ctaggaccag ataatacaac aattgcctgt
    13261 cttttttctt ctggaatttc ttcagccaaa acttctgaga ttcgtttatg cgtatcttgt
    13321 tctagtcctt tacttgcatg tataatgatt ggcttagtat tcattttacc aataagttcc
    13381 tgtgcgactg aacgaatcgc ttttgttgga acaacaaata aaatagcatc tgcgttatcc
    13441 actgcttctg ccaattcttt atatccgata atcgattctg ggatcgtcaa atcaggtaaa
    13501 aaatgctgat ttgtatgata cttattgatt tcatcaatct gttcaggtac atttccccaa
    13561 atacggacat catgcccgtt ttctgccaat gtttgtgcta aagcagtgcc ccaagatcca
    13621 ggaccaagaa ctgcgatttt ttgtttcatg gatattcctc caaataaata attgataatt
    13681 tccattatag tatacatttc ttaaagttgg gactaatttc cattgttttt aagtgtttgt
    13741 ttacttcttt tatcgttttt acttgaaata atcaatgata tgttacaata gtctacattt
    13801 tatttttaca ctcgttatgc tttgcttgtt cctaagagga agcagttttg acaatgttac
    13861 taccagcatt actattagga ggttaggaaa cttctcctag tgagtattga tttaaaatac
    13921 ataagagaca gattgaacat ttctaaatct gtcaggtcct gcaacggaca gattgtctct
    13981 gttgacggtt gacataggaa cttttgtttt agtcaacatt ctggatacaa aacgctatgt
    14041 aaactggcgc aactcgttgt acttggactt ttactacgga tccatgcaac aactaaatag
    14101 tactattgca taacaaaaaa tggttggcac ccacatgtcc cattaaacag attataagtt
    14161 gaactgtaga taatgcaaaa aatgtgtttt ataacgtaat tgatgccaat attttaaaaa
    14221 aataaaggga gcagttatcg ctgctctctt tattttttat attcttttta tccagtctat
    14281 cctaataatc aaactgacga tagtagcggc gtatctctaa tggatggcag ttcaactgct
    14341 ccacatgagc atcgatgcgt tgtgtcacta catgcatcaa taagaaagac aaaacacgtc
    14401 cgcgatattt ttcactgata ccttctactg gatagtcttt tgtgtctatc aatgtataat
    14461 tgctgcaaat ttttggcaaa agtttagcca cacgttcaga taacactctc tgttcatctt
    14521 cgcctaaaaa taatgtgact ggggttgttt cttctacgat ctctaacgtc ccgtgaagaa
    14581 actcggcagc atggatagat ttcgatggaa gccagctttg ttcttcccag taacacatgg
    14641 catatgaata aacagctccc cattgattcc ctgctccaat aaaataatgc atactatcac
    14701 gtcgatgttt ttctgcaaat gataagccaa atgcatctgc ttttttctct gcttccacta
    14761 accctgttgg taaataacgt tcgagctgtt catagtattc tgaataagct tcgaattctc
    14821 cattcaaata catcaatcga tctgctgcca taaaaaattt gatttgttct gttccaggag
    14881 ctggataagt gaccacaaaa tcgcatagct gagacaactt actgttcgct ttatcgataa
    14941 atccaatcag tgtcgctcct actttcttga tttgttctac tgctttcact acttcttgag
    15001 ttgtaccggt aacagaggac aaaataacga tagaatcttt tgttaatctt ttgtttccag
    15061 tagtgtaata ttctgcagca tgctgtacaa agacaggcaa gttgcttttc ccattcatat
    15121 aagtgacagc ttgcatcgag gaagcatacg ttccaccgat tcctagataa tagacagcgt
    15181 caaatttttc cgcataaagt ttatcgatga tttcttctac ttgcggacgt aaagctagtg
    15241 cgccttttat tgctttgatt tgttcttctt cattgaattt cagcatgatt tccacctctt
    15301 ataatttact tttcaagact gtatcaaagt cttcaaaaat ctttttgttc aagtcaatac
    15361 ctttagctac tgcggtttta taagcgaata gttgaaacgg aacgacaagc gctaatacag
    15421 acagatattc atcacattct attgctaatc caagtgtttt ctcgtttctt gctttttttg
    15481 tggtaatggt gagagtctct ccaacgtacc gactcatata tctttgcaac ttttgcgaac
    15541 gttccttatt tacactttcc ccttcaataa agaatagcaa atgcgaagca tctgcctcca
    15601 ggtatgggcc gtgcatataa gcttctaact caaatccttg tgacggaacg cggattgttt
    15661 cagtcaattt cgtctctgct tctttagctg ttccccagtt tggaccatat ccaatggtga
    15721 cgaaacgctg tgctaaacga aataaacttt gatatccatc aaaaaattct tccgtttttt
    15781 gaataatcgc tggtaaatgg ttgattattt tgcgcaactg ttgcatgtag tcttgttcta
    15841 tttttttgct gattttattt ttacttattc caattcctat ccctaagagt agtaactgta
    15901 aaacagtcgc agaatagcct tttgtaacga agcctactga ttctaccccg gcacctaaat
    15961 caataatttg tgcagcttct aaagcaagtg gactttgcac gtcatttgtg atagcaacaa
    16021 caggtaaccc ttgtttttgt atcattttta ctgcttcaac agtagaagca cttttcccgc
    16081 tttgtgacac agcaatcaca gtatcgattg aaggagaaag ttttccataa ttgaaaaaat
    16141 aaaaaggttc ttgaatatcg acagtaagat caccataaga ttccaatgct ggcttcgctg
    16201 ctaaacaagc gttataagat gaacccgttg ctaagatcag taaattcact gtttttttca
    16261 tatgttctct tgtcgaaaaa tcattctttt tcaagatcgt acttagtact tccttttctt
    16321 catagatata atcttgcatc gtaaacattt tctctgctcc ttttttaaaa aatccctatc
    16381 cacgaaccaa aaattccaaa gaaagctagt ccgatcaaga tcgttaatgg tttcacttct
    16441 ttcttcaata gataaaacac tatgccaaat gctccaagac ataagatatt tggaacgata
    16501 tcatcaaaaa tactttgaac agtcacagca ttttctcctg aaccgatttt taaaggaata
    16561 ttgatggtga tcatcgtggc agtcattgct ccaacgacca tcagtccaat aatagacgcg
    16621 cctaatgtca aactttccat cataccgttt gcctggatct ttttcaaaaa acccgttcct
    16681 aagcgatatc cccaacctgt tgctagatag cgaaacagaa tgtgcggaat attgaaaatc
    16741 aaaatgaaca agatagggcc taaaatattt ccttgcatgg ctaaagaggt acccacacct
    16801 gtggcaatca atcgcaaagt tccccaaaag aaagaatctc ctaaccctgc aagaggtccc
    16861 atcaaagatg ttttgatact atcgatcgca gtcacatcaa attcaggatc atccttattt
    16921 tcttcctcca ttgcagccgt gattcctaaa atcagtgtaa cgatatgtgg ggtcgtgtta
    16981 aaaaactcta gatgccgttt caaagctgct gccatttctt ctttcgactg atataacttt
    17041 ttcaaaatcg gaatcattgc ataaacataa gccatattca tctgacgttc ataattccaa
    17101 gaaaactcca tttgaaaaga acgccaaaat acgtgattta gctctttttt cgttattttg
    17161 ctgtttttga tctcagaatt cttcatcttc ttctacctcc cctgcagttg tttgaagtgg
    17221 tagttgacgg acattcataa tattgactac cacaactgct aaaatcgcac caaaaatagc
    17281 tactccggtc acaggaatct ctaagtaaga agctatagca aaacctaaga aaaaatatgg
    17341 tgcaacttgt ttgttgatca gcaaacgagc aagcatcgca aaaccaagag ctggaatcaa
    17401 ccctgtagct actgacaacc ccttttgaac gaagtcagga atcatattta atagatttcc
    17461 gatcgtattg cttcccacca tataagaaac cattaccaca acaccaagca tcaaggaaag
    17521 accgataccg gcaagcaagt gcatatgctc gactccttta taatttcctt cttctgcata
    17581 attgtctgct ttatggttca taattggaat caaaagccct aagtaaatat ttttcaatat
    17641 caatgtcaac gtagcaatcg gcaaacctag taaaagcgcg gtttctgtac cggctccagc
    17701 tgtaatagca aaagccgtcc ctaaaatccc accggtcaca acatcaggtg gaatcgaagc
    17761 acctactgag aacgatccga taaatgctaa ctctaaagtt gcgcccataa tgatcccagt
    17821 ttttacatca cctaacacga ttcctgtaaa cagccccgtc acaatcggac gagaaagcaa
    17881 cgatgtccct agtgcatatt ctgattgtgc gacaaatgca acaattccta ataagactgc
    17941 ttgtacaatc attgaggttc ttcctttctt acaaaacttc tcttacatcc acttttttat
    18001 ctgctggtac ttgacggatt tctacttcta tttgtttgtc aattaatcgt ttcaagcgtt
    18061 cctcctcttc tggtaaaata tttaccgctt ttccgatgct gcgagtacca ggttttgcct
    18121 tgatccctcc taagttgatg gttttgattt ctggatacgc ttctgccagc ttatatgcat
    18181 cctcgatcga ttccactacg atgaataact tatatttatc tgtcaccccg cttttcaacg
    18241 cggcaatcga gtcatcaatt gatttgatca ctagtttgac tccttgtggc ttggctaatt
    18301 tgatcgttgt ctttcgtatc tcattcgtag gtacatcatc attagcaatc aaaatacagt
    18361 ctgcgcctat tgtttgtgtc catgaaaaag ctacttgtcc gtgtaataac cgatggtcga
    18421 ctcttgtcaa tacaatcatt tttcttcctc ctaaaattcg tcttcttcta ttttctgatt
    18481 gagccgctcg ttacaaaact ggatcatttt ttttgaatca gttagcacct gctggatcaa
    18541 aacagttgtc tctacttcag cgtccaaccg agatactagc tcaatcaata gtggcaaatt
    18601 caatccggca acgagataga catgatcccg attgatatat tgtaagaatt cgttgttgac
    18661 acttccgcca aaaagatccg tcagaacaat gatttcttta tctttgtacc tcataaaaag
    18721 ctgccttact gtttccgcta aatcaaaatt ctcatcagta tagcaatcga atacagtaat
    18781 agaatgattt ttcccataga tcagctctaa tgaatctaat atccctgaag caaattttcc
    18841 atgggaagct aagataattt ctctatccac tttttcatct cctcttttca cttacacata
    18901 ctaaaaaagc aagttgcatg ccaaaattag tggcaacaac ttgcttatgt tcaaaattct
    18961 tcttctatcg agagaaactc tgtatcttca ctcaaaatat catagatata ggcaatctca
    19021 gaattgggga tcatgacact ataatgctct tcaatgacac taaacgcaga tttaatagca
    19081 gataaccctt ctttttgaca ctgcttccat ttctctaatc cttgataggt ttcgattggc
    19141 atttgtcgga tcaatcgttc aatgagacag ctcacatgga catacaacgc taattttttg
    19201 ggattgctga tgcttcgatt caactgcacc tctaattctc tcataaaatg atcgatttct
    19261 cccatcacct tctctgtatc tagaatagtc acggaatcca gtactttttc caatgaaaaa
    19321 ttacgaatga tgcgctgatt gaatatttcc ttctctgaag cattcatagt agtgtccaac
    19381 cattcagcta gtacagacat cttttccccc gagatgaggt cttctaatga aagatagtcg
    19441 atattggtga tatcaggatc tgtggtgcca atcattccta cgacttcgta tatggaaaat
    19501 aatgggtcac tgtttttctt atcttttaat tgctgatatt catatgggat gattttcaac
    19561 tgacaagccg taggtaagct tttttctagc agttcactta agtggaccgc cgtaccgatt
    19621 ccagtgaagc aagtagtaat gagtgctttg ggtttgtttt cctctggata gagcagtcgc
    19681 cattctggct ggatctgtcg aacagtctct tctgctatct cttctaatga tacatttttt
    19741 tgcaggcatt cccctactgt gattgctaaa ggtgtcgtca cattattcaa aatcaaaagc
    19801 ggtacggata actgtttttt aaaaaactga tggatttctt tcagagatcc catgtctact
    19861 aatatgatca atccatttga aacatcgctg ttttcgcaat aatcaaggat ttctgaagca
    19921 atctgctgtg gtgtgacatc tagtggcata tcaaatgatt caaatagatc ctcttgtaat
    19981 aaacgattta ctacatttgc catactgcta gcagttgcat aaccgtgagc agcaatcatc
    20041 gcttttggca gtcgtttttc ttttgaccat ttcgcttttt ttagatagat cgtcagtaaa
    20101 atccgatcca tacttgtgtc ttcaatatct aatttgatct tacttaattc cagaattcgt
    20161 tggacatagt gataactaga tggataagac tgagaaactt gttgttctaa ttctttgatt
    20221 agttggataa tatcatgttc ttccggtaac catttgatag tgcttcgctg atagagatag
    20281 taactcaagg catagacact gtttccatcg aatttgattt gataggcagt ttccatttgt
    20341 cgaaaggtct ctcggataga ttgtgtccaa taaaccagca gctcgtgttt ttcttgtcta
    20401 ctggtctcaa acagcaaaaa atcaaataat tgaatcactt cttgctttaa ttttccttcg
    20461 caagaatata gcagacagtt atttttcttg aaatcaatta ggatttgctc aaaactttta
    20521 acgattcgct gctgttcggg ctgttgcttc tccattaatt gctctaaggt ctggtcttgc
    20581 gtaatataga ttccttgctg tgctgtattt ttagtaatag gctgcgcaag tagttctttt
    20641 tgcaaatgat ggatcgtgac atggatttca ggctgttcac gctgttcagc atatgctttt
    20701 gctgctgaaa ctttgacgat atttttcagc tctcctatgt ttccggataa tttctgactt
    20761 gttaaaagtg acaaagctgg tccactgact gacaaagggc tccccatttt tctttgttct
    20821 tcgagaaaaa aagagtaaat cagttctagc cgttcattac gactacgctg attaagtgca
    20881 ggtagttcga ttcggatagg tattcttcga atgaaagttg ttaagaaatg actagtaatc
    20941 tcttcagtcg tagcaaaaaa gagacgtgtt ttgatccggc gtgacaaatt aggttctccc
    21001 atacgataaa tcacaccttg atcaagatag gtgaacagtt tttcctgacc ttctggtgtt
    21061 aagcgatgta cctcgtctaa aaacaagatc ccaccatctg ctgcttcaaa agcccctttt
    21121 ttattttctt ctgcaccagt gtacgctccc ttaacatgtc caaacaaatt gctagtcaaa
    21181 agttcaggat tatctgcata ttgtgcacaa ttaaaagtga tgaatggtgc agaatcttct
    21241 agcagatcat gaagcagaca atactgatag accaaattaa ctaaataact tttacctgtg
    21301 ccactttcgc ctgtaatcaa aagtggtaat ccgccatctg gatagtaaag agctgttttg
    21361 atttgttcga tactttcttt caaactggcg tcgtatccga tcataaaaga gaataagtct
    21421 tttggttgcg cgaaaaaagg ctgttcctct ttgagatcat cgatagaaaa ataaaaattc
    21481 gtgcgtaact taaaaaattg tttttcaaaa gcttctttgt ggaaataaat cactggtcga
    21541 gaattgattt tgactagtag ttgctcatca tttaactggt tcaaataatg actgactgtg
    21601 tttcttttta ccccaaaatg atcagctaac ctttgtgctg taaagacctc gttcatatgt
    21661 tctaaatcga aaaaggctgt ctggttctct aagtaacata aaatttcctt cttcaacaac
    21721 ttattcaccc ctcctccatc atagaaaacg gattcatttt gtcaataaaa tctttaataa
    21781 agaattgaaa aatatatctt attatagaca gcagcctact tatcccttat aatttttatt
    21841 ctaaaaaacg tacagttcct tccagttttt atactggaat ttcaacatat gaaagaataa
    21901 ggaggctatg actattcaat gaaatcggat aaatataaaa acaggaaaca tacttcctgg
    21961 aaaacttttc gagaaatcat cggatcttat ctcgctgtag ttgtattttt gcctttgctt
    22021 tatatggcta tgacagaaca aactcgtttt attggcgtag atacgcaata tatagccgaa
    22081 acaggatttt tattcatctt tatcttgatt tttgcgttct ataaatc
//
LOCUS       DACBYO010000044        21534 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.044, whole genome shotgun sequence.
ACCESSION   DACBYO010000044 DACBYO010000000
VERSION     DACBYO010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.044"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..478)
                     /gene="msrA"
                     /locus_tag="IVD26_001614"
     CDS             complement(<1..478)
                     /gene="msrA"
                     /locus_tag="IVD26_001614"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP6079579.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHAR"
     gene            complement(498..1211)
                     /locus_tag="IVD26_001615"
     CDS             complement(498..1211)
                     /locus_tag="IVD26_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAP6079580.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(1214..2110)
                     /locus_tag="IVD26_001616"
     CDS             complement(1214..2110)
                     /locus_tag="IVD26_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP6079581.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(2268..3110)
                     /locus_tag="IVD26_001617"
     CDS             complement(2268..3110)
                     /locus_tag="IVD26_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP6079582.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            3242..3895
                     /locus_tag="IVD26_001618"
     CDS             3242..3895
                     /locus_tag="IVD26_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP6079583.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(3958..4485)
                     /locus_tag="IVD26_001619"
     CDS             complement(3958..4485)
                     /locus_tag="IVD26_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP6079584.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(4505..5452)
                     /locus_tag="IVD26_001620"
     CDS             complement(4505..5452)
                     /locus_tag="IVD26_001620"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP6079585.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLRNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(5464..7350)
                     /locus_tag="IVD26_001621"
     CDS             complement(5464..7350)
                     /locus_tag="IVD26_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP6079586.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(7510..9588)
                     /locus_tag="IVD26_001622"
     CDS             complement(7510..9588)
                     /locus_tag="IVD26_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP6079587.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(9601..9876)
                     /locus_tag="IVD26_001623"
     CDS             complement(9601..9876)
                     /locus_tag="IVD26_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079588.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(10238..10693)
                     /locus_tag="IVD26_001624"
     CDS             complement(10238..10693)
                     /locus_tag="IVD26_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079589.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(10847..12055)
                     /locus_tag="IVD26_001625"
     CDS             complement(10847..12055)
                     /locus_tag="IVD26_001625"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAP6079590.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(12167..12499)
                     /locus_tag="IVD26_001626"
     CDS             complement(12167..12499)
                     /locus_tag="IVD26_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAP6079591.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            12647..13522
                     /locus_tag="IVD26_001627"
     CDS             12647..13522
                     /locus_tag="IVD26_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP6079592.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(13604..14185)
                     /locus_tag="IVD26_001628"
     CDS             complement(13604..14185)
                     /locus_tag="IVD26_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAP6079593.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(14191..15450)
                     /locus_tag="IVD26_001629"
     CDS             complement(14191..15450)
                     /locus_tag="IVD26_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP6079594.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(15452..16498)
                     /locus_tag="IVD26_001630"
     CDS             complement(15452..16498)
                     /locus_tag="IVD26_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079595.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(16733..17008)
                     /locus_tag="IVD26_001631"
     CDS             complement(16733..17008)
                     /locus_tag="IVD26_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAP6079596.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(17251..18561)
                     /locus_tag="IVD26_001632"
     CDS             complement(17251..18561)
                     /locus_tag="IVD26_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAP6079597.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(18743..19972)
                     /gene="rpsA"
                     /locus_tag="IVD26_001633"
     CDS             complement(18743..19972)
                     /gene="rpsA"
                     /locus_tag="IVD26_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAP6079598.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(20107..20787)
                     /locus_tag="IVD26_001634"
     CDS             complement(20107..20787)
                     /locus_tag="IVD26_001634"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAP6079599.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(20836..21471)
                     /locus_tag="IVD26_001635"
     CDS             complement(20836..21471)
                     /locus_tag="IVD26_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP6079600.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
BASE COUNT         5923 a         4519 c         3663 g         7429 t
ORIGIN      
        1 ggcgtgcatg gtttctttta aaattttcag gatgcttttt ataatactct tgatggtctt
       61 cttctgctag ataaaatggt tgggctggtt cgatttttgt aacgattggc tgttcgaaac
      121 gtccactttc agctaactgt ttcttacttt tttcagcaat gatccgctgt tcttctgtca
      181 aataaaagat caccgggcga taattgtcac cgcgatcctc gaattgtccg aaagcgtcag
      241 ttggatcagt ttgctgccag taaagttcta ctaattgttc atatgaaatc aatgttggat
      301 catagataat ctccactgct tctgtatgtc cagtcgtttg gctttttact tgttcataag
      361 tcggatctgg tacatgccct ccagtatatc ctgacatcac tgtatggata ccaggaagcg
      421 tgtcgaaagg ctggatcata caccagaagc agcctcctgc aaatattgct cgttccatta
      481 tgattccccc tctaatacta ctcatccgat gattttttat tttcttttgt cttgctttca
      541 gtactgctgg tgctagtttt gttggtattt gagttgtttg aagcatcaga ggtatctttt
      601 ggcaaatata gactaaaccg aatgtcatca tttactaagt cgattttatc tgctttaata
      661 tacatcccgt tttgcattcg gaattgatcc aacctaagca tgatagtcag atcatctgta
      721 ttgacttcga tccaatctgg taatttatag tttctcttga tcatattcat cacatctttg
      781 attggcaaac tcaatgttcc gatagaaaga cttctagctt ttagttggac atttccgttt
      841 tccatcacat acggatcaaa atataaatag aaatcgatag gaaaacctag tacttcgaaa
      901 gtaccattga gtagtgcttc attttccaaa taaaatttat attcaatatc actatctttt
      961 tgatactcac taaggaaaaa gctgatgatt tgattgactt tttctttatt tgaattgatc
     1021 gttaagacag gatctccttg tctttccgta agagctggta tttctgggag ttctggttcc
     1081 cgattagcaa aaatacggct gcctaaaaat acggtcgaac caagtactac cccaagaagg
     1141 ataaggaagg cgaatttcca gtaatttgtt ttctttgttt tgtttgaaga tacgtcagat
     1201 cttgttttca tgtttattga tcatcctcct tctctaacca ttggttttgt gtctcgatca
     1261 gctgatctct cactgcattt gccatcaatt gataacctaa attatttgga tggaaatgat
     1321 cttcttcata gagcacatta tttttgatgc catttagatt ttctgtcgtg ctagttgttt
     1381 gatctgttcc ttcttctgtg acacctactt cctgattcaa tccttgataa agcaaatcat
     1441 tgattgggat aaagtagcag ttcggcattt tttttgtcac cgtttctgtt cctttgttcc
     1501 aattgttaac aattgtctgc atgtcagtga tctcaggaaa gttcaaataa aatggattgt
     1561 agatgcctaa aatgtaaata ggtgcggttt tattgaggga tcgaaattct tccaatagtt
     1621 ctgtgacatt ttcctgatag tttttcagtg gctttttaaa ggaattgacc gttaacccga
     1681 ataaattatt ttggataact ttcatcaaat cattaccgcc aacagtcagt gtgataaaat
     1741 cagctgtttt gatattgttt cgaatttctt cttttgtttt tactcgcttt aagatctggt
     1801 cacttcgttc accatttaca ccatagtttt ctgtttcaac cgcggtcaaa ttataacggt
     1861 cttttagatc atttgcgaca aggggaacga atcctccttg cttggtttga tctcctactc
     1921 cttcagtcag cgaatctccg atagctatgt agtgaagttt ttctttttta tttggatctt
     1981 ctctcacagt agttactggt ttcattagtg ggccagcttt cggtatagaa gcagctaaac
     2041 ctgcatagat gatgatcgca attaataatg ggaacaaaac gaggatcaaa tgtcgtttcg
     2101 ttaatttcat tttttcacct cttgtattcg attggttcta atgttatcaa aaattttatc
     2161 aaaaaggtag tctttatgaa aaaagaaaac aattattttc ctaattttat aaagaaaaag
     2221 agaataagct gcaagccttt caggctgagg gcttatcctc ttttcgacta atctacataa
     2281 tacatgattg caaacgcgtc tttaccagta tgcgtagcga taaccggatt cgtatgcagt
     2341 acagggatat gcatgtccgg gaataattct tgcaaaccct ctttgaattc ttgcgccaat
     2401 tcttttgcat ccgcatgtga aataccgatt tgtcgcacat ttggcaattc tttcagttca
     2461 tttttcaaat tattaaacca tttatcgaac gttttctttc ctcgcccctt agttacaggg
     2521 attaattcag aatgggcgaa attcatcacc acgcgtatgt tcaaaacact agacagcaaa
     2581 ccagttgttc ggctgattct tccacctttt accaagttat ctagtgtgga tattccgatg
     2641 tataattttg tattgtcttg tacttttttg acttcttcaa ggattttctc tactgtttta
     2701 ccttcttttg ctaattcagc tgctcgaatt acctgaaaag ataatccttg gtcagtggta
     2761 tcactgtcga taaccgttac tttcgttttt gttagattac tggcttgtct tgctgcttct
     2821 actgttccac tcaagccttt tgtcatatgg atcgaaatca cttcactgcc gtcttctcct
     2881 agctcatcat acatcgagat gaattctcca attggtggtt ggcttgtttt gggcagattt
     2941 tttgctttcg ccatcatttc cataaatctt tcgccgtcta gttggtcatc atcgggatat
     3001 actgttccgt cgatcatgat ggatagcggc atgacacgaa tgcctaaagc atcgcgtaca
     3061 tttttttcca tcgtacatga agaatctgtt acgattttta catttgtcat tattttctct
     3121 ctctctttct ttaacaagat gccttattca tgttaaacta catgtaagac aatttctatt
     3181 tttagtataa cagacaaata atgatttttc attaattaca cctagtaaag gagccgtttt
     3241 catggaaaaa acgaaattta atcgaacgta tgaaatatta aatgaagtgt ttaatgcagt
     3301 cacccatgga attgggactg gattgagtat cgcgggacta gtggttcttt tagtaaaagg
     3361 tgcccacttg cattcctccc tccatattgt ctcttatgct atctatggat cgatgatgat
     3421 tcttttattt ttaacgtcta ctttgtttca ttcattgatt tttacaaaag caaaaaaggt
     3481 gttccaagta ttcgatcata gttcgatttt tcttttgatt gcaggaagtt atactccttt
     3541 ttgtttgctg agtatccgag gatggctagg ttggacttta tttgtattaa tctggttgtt
     3601 tgcgattctt ggcattatat ataaagcgtt gacgttgcat aaacgggaga gagtatcaaa
     3661 agtatctacg atcatctata tttttatggg gtggctctgt gtcgtggctg ctgttcctct
     3721 ttatcactct cttggaatga ctggtgttat tttgatggta gcaggcgggc tttcttacac
     3781 gataggcgca ttcttttata gcttgaattc tatccgctat atgcatgttg tttggcattt
     3841 gtttgttatg ttaggtgcag gttttatgta cttctctgtt ttattcttta cttaataaaa
     3901 aaaataaagc tatggatggg acagctctaa ataacagcta gtctatccat agctttttta
     3961 tatcgtcaat tcgcctgtcc cgctttttac aggattctca ttacgctgat acgtttcaaa
     4021 ttgatgcgga taacgatttt tttcatccat ttctccttga ctagtattga tcagtgacca
     4081 atcagaccag tcaacaggtg gaaaataagc atctccatcg aatacatgat ggatgactgt
     4141 acggtataat atcgtacaaa atggcagaaa ttcttgataa acagctgacc ctccagcgat
     4201 gaaaaagata ccgtctgttt ctttttccag agcaagcacg tcttccacac tatgcatgac
     4261 atgcacgcct tctgctttat aggaagaatc tctcgtcaaa acaatcgtct gacgattcgg
     4321 caacggacgg ctacccatcc cttcgaatgt ttttcgtccc atcactagtg tatttgcttc
     4381 tgtcatttgt ttgaagaatt tcagatcatt tggcaaacgc caaggaagac ggtcttcttt
     4441 tccaatcaat ccgttttcat cctgtgccca aattgcagct aacattttct catcctttct
     4501 gattctaaac agcgatagga gctttgatcg ccggatgtgg gtcatatcct tctaattgga
     4561 tatcttccat ctcaaaatca aatactgact gcttttcctg attcaaaact aaagtcggaa
     4621 atgcgcgtat ttctcggctc aattgttctt tcatttgttc gatatgattg atataaagat
     4681 gagcatctcc taatgtgtga acaaattcgc caaccgctaa acctgtttca tgtgcaatta
     4741 ggtgagtcag caacgcataa cttgcaatgt tgaacggaac gcctagaaac acatccccac
     4801 tgcgttgata caattggcag cttagccgtc cctcttgaac ataaaattga aacatcgtat
     4861 gacaaggagg caaagccatg ctaggaacat cttccggatt ccatgcagaa acgatcaatc
     4921 ttctagaatc aggagtcttt ttgattgctt cgatcacttg tttgatttga tcgataaagc
     4981 caccgtcttt tgtttcccag tgacgccatt gatagccgta gatgtgtcca agatcgccgt
     5041 atgtttcagc aaaggaatca tcggttagga tcttctcgca aaaaagcttg ctctgctttt
     5101 tatattcttc attgaattca ggatctgtca aacatctatg gccaaaatca gtcatatctg
     5161 gtccattata gtctggactt ttgatgtagc gttcaaatgc ccattcatcc caaatatggt
     5221 ttttatttcg taatagatag cggatattcg tatctccttt taaaaaccaa agcaattcgc
     5281 ttttgatcaa tccaaaaggt actcgtttcg ttgttaacaa aggaaaccct ttttgcagat
     5341 caaaccgcat ttggtatccg aataagctta atgtgcctgt gcctgttctg tcttctttac
     5401 gatgcccttc ttccaacaat tttcttccta agtcaagata cgcttgttcc atcctttttc
     5461 ctcctaatct tctacccatt cactcaagta ttcccaccgt gccatttttt cttcaagttg
     5521 tgcttctgtt tcagatacgt cgttttgcaa ttcttgtaat cgagtgaaat tatctccttg
     5581 atgattcatc tcttcttgga gcaatgagat tttttcttca agttctgcaa tctcatcttc
     5641 aatcgtttcc cattcttttt gttccatgta agataatttc ttcttttcag caggttcctt
     5701 gctctgtatt tttggtttcg ctttttcagc aggctgctgg gtctcttttt gcttcagtaa
     5761 ataactggac atgtttccgt aataaagttc ttgttttccg tttccttgga atactaataa
     5821 cttatctgct accttgtcca agaaataacg gtcatgggaa acagtgatca cagcacctgg
     5881 aaaacttcta aaataatctt ccaaaatcgt caatgttgct atgtccaaat cattggtcgg
     5941 ttcatccaat aataaaacat taggttgctg aatcagcagt ttcaacaaaa ataaccggcg
     6001 tttttctccg cctgaaagtt tgcctatcag tgtcccatgc ataaatcttg gaaataaaaa
     6061 tcgttcaagt aattctgcta ctccgatttg actgccatct gctgtttttg cttcttcagc
     6121 agcttcttgt aagtaagcaa tcatccgttt atctggtgcc atttcttcat tttcttgtgt
     6181 ataatacgca agatgaaccg tttcaccgat agacattgta ccgctatcca ggggaattct
     6241 gccagctaga atattaagca atgtcgattt tcccgcacca tttttaccag taatacctag
     6301 tctttcccga gattgaatca ataaatctaa atgttctagc agtgtttggt catttatacg
     6361 gtaactgcca tctttgattt ccagtacttt tttccctaaa cgttgtgtcg ctaggttcag
     6421 ctctaaatca tcttcttggt ttacttggta caagttctcc tttagatctt cgaaacggtt
     6481 gatccgtgct tgctgcttgg tgccacgtgc ctgtacgcca gccctcatcc aagctaattc
     6541 ctgtttataa agccgcttgc gcttttcttc ttgttctact tctacacgat cacgttctgc
     6601 tttttctaag acgtaagctt cataatttcc tttatactcg tataattttc caaatgaaag
     6661 ttcgaagatt cggtttgcta ctctatctag aaaataacga tcgtgggtaa ccatcaatag
     6721 tgcgccacgg tattgtttca aatagttttc caaccactcg atcgcttcat aatctaaatg
     6781 gtttgttggt tcgtctagta atagtaaatc gggttcatca atcaacactt gcgccagact
     6841 aactcgtttt ttctgaccac ctgataaagt actgattttt ttatctaatt cactgattcc
     6901 taatttttgc aaaataatct ttgcgttggt atctgtagtc caagcatctt ctttattcat
     6961 ttgttcttct gctttagcat aacgtttttg cacatcaggg tcttctccgt tttcccctag
     7021 ttcgatcaat gcttcctcat atgctcgaac agtttggatc aaggggctgt ttccttgaaa
     7081 gactgcttgg agaacagtta attcatcgga aaattcagct gcttgagaaa gataaccaat
     7141 acggtaatca gttggataaa acactgtttg ccgatcaccg tcgctgctat cgataccggc
     7201 aataatattt aagagacttg ttttacccgt cccgttcgtc ccaatcaacc cgatacggtc
     7261 tttttcgtgg accaaaaaag aaatctggtc aaacaaatct ttttcaccat aagttttttt
     7321 gaggtcagtt acttttaatt ctttcaacat gttccctcct tatcttggat attgtatcat
     7381 aaaaatagtg aacttcagga aaattttttt ggtatttgtt ctttttgtgt tctcaaaaaa
     7441 agaacaggac cgattcgatc ctgttctgat atgttttgtt ttttataaaa cttgaaaatt
     7501 tttacctttt tattttattg gactcgtttt ttttgacttt gctcgaaacg caaatcggaa
     7561 agaaaagtta tcagatggtt tgttcatcgt ataagattct aacaaattga tattcctgcg
     7621 atagctgttc gcagaaaacg tcgtgatttt ttcagcaact tcgtattcat caatgatttt
     7681 tctttcaaga taataacctc ttagcatttt tttcgtaaac agactatctt gctggatcat
     7741 ccacgaagaa atcaaattcc ccgagttcat ttttattcct tcaagtttgc gttgctggat
     7801 aaaaaattga accatcgttt catcataaat atcagtcaag ttatctaaac tttcaataat
     7861 caactgagta tttttttgat atgtctctct gatttcttgg atatcttcat cactaataaa
     7921 tgtctgacga tcagcatatc ttctttgcca aaacattttc ggatggagaa cgattcgcat
     7981 taacctacgg acaacaatga accaaaagcc gataaaagac aaaatctggc ttgtgataga
     8041 atgttcgaat cgagaaagaa aacgggagta aaaacgataa ccattagaag aaagcttgcc
     8101 cgaacgataa ctttcatcca atccatcccg ttcgatcgac aaaatcagtg cttgtatttc
     8161 ttgtacttct tgcttttcat catcggttaa atcttccaag tacagatcac gtatccgttc
     8221 ttgataattt tctatcactg cttcagtggc taaaaattct tttgtattac gatcaatttc
     8281 ctttatttct tttcgcaaaa cttcaacgac ctcttctaaa atcatcaaag cattcaaatc
     8341 cgtgcttttc gcttcctctg tttccgtcag cataggcaag acaatgatcc ctatgaccaa
     8401 agtcactaag atgacacccg ccgtcagaaa caaaagcaaa gaccgctggt aaaacatcat
     8461 attattgatt gaaaatggca aaataaaaat cgtagccaaa ctgactgttc cctttacacc
     8521 gccaaatgtt aagatcaaga tctcgttcaa ctgttttttg aactttttac tgccatcttt
     8581 gaatacataa aaaagactga tagaaatgaa tctgatcaca aaaagcatga cagagattaa
     8641 tacgataatc gctaataaaa gaccgtttgg atataaaccg tctccccata ctggcgagaa
     8701 cacttgcgtc aattcgattc ctaaaaatat aaatactaat gcattcagtg taaaagcaat
     8761 agttgtccat gtactgtggg acaagctcga caattctgca tcaaacacag agattttcct
     8821 aaaaccagaa gcttggagaa tacctgctgc cactgcagca atgattccag atacatcaaa
     8881 tgcctctgcc aatacatagg ctagaaaagg aagcaaaagt tcgatcagca gataccctgt
     8941 gacatcttgt gctgatgctt tttcgatcaa atgaattatt ttttgtttga accagacaag
     9001 caaaaagccg atcaaagctc ccccaatact agaaactact agactcatcc ccgcgtttac
     9061 tgctgaaaaa gatccggtga tcagcgcacc aagagcaaac tggaaggcag taacaccaga
     9121 tgcatcattc aaaagacctt ctccttccaa aatatgcatc gcctttttag ggatattcac
     9181 tcgtccagaa agagaactga ctgctaccgc atctgtcgga cctaacgctg ctccaaaagc
     9241 aaagcaggca gcaagtggga cacttggcaa caggaatgat aacgtcgcac ctaccccgac
     9301 aagggtcaaa atgactcctc caaatgccaa gaacaaaatt gtcccgaaat ttttgagaat
     9361 cgaagaaata tctgcttttt ctccttctct aaataacaat ggtgcaataa tcataactaa
     9421 gaacaattca ggttcaaaat cgattgattg tccccactct gtcagaccta ataccactcc
     9481 aaggaaaatt tggatcagtg gagctggaat cattggcaaa atgcggctag ctatgttcga
     9541 taaggtgatc gttactgcaa atacaataac taactcagca aattccatcg tccatcccct
     9601 ttatttttta ttttgtgtaa gcatttttaa aaattgttct tttttcttta aaattttggt
     9661 ttcgactact tcaacctgtg tttggttccc ctctaattca cactgtacac gttttgactc
     9721 caaacgaagc agatcatgtt tcagacgttc caactgacga tacatcaata tatttctttt
     9781 acgcaactta caaagtattt gacggcggtc atccatcgaa agggcgccat agcgatcatg
     9841 caacagtttt ttttgttgtt caaaactctc tctcattttc cagatctcct atacacaaac
     9901 ttccatcatt atagcaaagt tctttttgga tgaaaaatat ttcattgttt catcgtttat
     9961 tgctagttag aaatttccat aaatttttca acgcctcatt ctattccaaa tagtatcaga
    10021 tatcaagtaa aacttaagaa agataaaagt ttctgacaaa aggatgttta ctttcccatt
    10081 cctgcctttc ttgttctttt atcacaacaa aaaaatgggg ctgcgacaaa aatcttgtca
    10141 cagtccctta ttctgaataa acggtgtgga agagacagcc tatcagtagt aataagacac
    10201 atctctttca cagcctcatt tttgcgtaaa aatcgattta ttcgaaaaat tccccgtata
    10261 catcttctac acgttgatct ggattgatca cgatatacaa gttacctgtt ttttcgctga
    10321 tttttgttga ttgatattga ttgtctaatc cttctgttcc tttatctaga tatgggaagt
    10381 acacaagatc aggtgtgcca tttcggtaaa ggatttccat tcgctcgata tcttcgtatt
    10441 tcaatgcgcg attaaacatg cccatttcca gtccgcctag gttgatatca tgtgtcgcaa
    10501 ctgcgtcccc ttcatggaag atttcgattt taaatccagc acacggatgg atttcaacaa
    10561 attcactgcc attgattcgt ccaaaacttg ttgtgatttg tttgatccaa agatcgccga
    10621 tatgacggcg gttgatcgtc caggtttctc catttctaaa ataaaatttt agcgctgtca
    10681 tttctttact cattaaaaag actcctttat gatgtaattt attcttgtac tacctcagtt
    10741 tagcacaaat ttatgtaagt ggtcacatct tatgtttttt cttctaatga cgtatctgcc
    10801 cactttaagt agccaacaaa gctgagcaga tacagtctag tgttttttaa atcaattttt
    10861 ctttcgataa aaaatccaaa acctgttttt tatcattttt tattctttgt tctacgacgg
    10921 ctttttcagc taattgcaaa gcttcactaa cccacttacc aggttttttt ccagtttctt
    10981 ctagcaagat tttaccatct actgctaatt cgcttaatga cttgataggt aaacgatcat
    11041 aggattctcc tacggcatcc atctgaggtg tttcgtcaaa atagatcatc aattcttcta
    11101 cttgcagtgc atgttttttg cctaagaagt acaattcgaa tggttccaaa gctccagttt
    11161 ctcgttgtcg tagtccttgg acaagtgctt gaacgtcttt aatcatttgg ttagaacact
    11221 tccacgattt caaaaaggaa cgaatctcat tttcttttag atccagttgg ctgatcaata
    11281 atgcccatgc ttggctctct tctttcaatg ggacggatgg taattcagca aaacgtaaaa
    11341 gtgcttcgcc ttcttctttc aaaccgggac agcaaatgta gcactctgtt tcaataaatg
    11401 catggattcc cgcggcccgt tcatttccca agagcatctt gatgaattcc acatttatac
    11461 gttctacaga tattttacct aatagctcgt ggttttcttt gatggcgtag aaggtttctt
    11521 cctctaattt gaaccctagt tgactgacaa aacgcaaccc gcgcatcatt cgtaaggcat
    11581 cttcatggaa ccgctcatga ggattgccta cagctcgcaa gatctgttct tctagatctt
    11641 gcagaccatc gaacaaatcg atgatttctc catcttcttt caaagcaaac gcattgatcg
    11701 taaaatctct tcttttcaaa tcttctgcca acgaacgaac gaattcgaca tgatctggtc
    11761 tacggtagtc ctgataagtt gattccgtcc gaaatgtggt gatctcatat tgttcatcat
    11821 tttctaatac caacacagtt ccatgttcga tcccaatatc tatcgttttt ggaaaaagct
    11881 gtttgatttc ttctggaaat gcgcttgttg cgatatccac atcatggatt ggctggttca
    11941 gcaagatatc acgaacactt ccacctacaa aataagcttc atatcctgca ttctctaatt
    12001 ttttcagaac tggaattgcc ttttggtatt ccagaggtaa ttgttttaat ttcatttttc
    12061 caacctttcc tgcgtgtttc ttgtcctgag ataaagactc agttgcatgg tgactgtttg
    12121 acaagtccgt ttcagagtct tcaaggccag gaccacttca tcttgtttac tcgtccttac
    12181 gctcaaagcg attatggtct ctttgattga atttttccat gtttttttca aaaacttcag
    12241 ttaagtcgat attcaatgaa ttagccatga tcatcgtaac gaataaaaca tcaccaagtt
    12301 cttctgctac cgagttaact ggttcagaag cctttttgct tttttctcca taagtgtggt
    12361 tgacttctct tgccaattca cctacttctt cagttaatcg agccatctga gctaatggag
    12421 agaaataccc caccttgaat tgctggatat attcatccac ttcctgctgc atactgtata
    12481 aagaacgctt tttatccatc tttttccctc caaaactatc ttaccaaaac tttaacgcaa
    12541 atcctagata agagcaattg agaaaatcga atttccatgc tacatttagg aaggaatttc
    12601 taaatggaaa ttctgtgaaa atacataatt gaaagctgga attcatatgg tcaaacgaaa
    12661 aacagtaaaa gaagttcttt ttatcattat aggaacaagt atttatgcat ttggtcttgt
    12721 ttacttgaac atcgctaatc atttagcaga agggggagtc tcagggatca ccttgatctt
    12781 aagagcttta tttggtattg atccagctta tacgacttta ttaatcaaca tcccattgat
    12841 tttactagga ggaaagatcc tcggtaaacg ttccttggcc tatactgttc taggtacact
    12901 ttctttgtca ttctttttat ggatctggca aagggttcca ctagaaatca atttacagca
    12961 tgatctactg atcgtttctc tacttgcggg tttagttgca ggtgtaggaa gcgggatcgt
    13021 ctaccgcatg ggtggaacaa caggcggcag tgatattatc gctcggattt tagaacaaaa
    13081 ttacggcatc actatggggc gttccctatt ggcatttgat atcatcgtct tacttgcttc
    13141 attaacctat atcgacttga aacgtatgat gtatacgttg attgtttcgt atgttttcag
    13201 tcgtgtgatt gattcgatct tagatggcgg atattctgca aaaggtctac ttgtcgtctc
    13261 caacaaaagc gaagagattg caccactact gatgaccggt ctgcaaagag gtgtgacttt
    13321 cctttctgga gaaggcgcat tctctggtaa ttcaaaaaaa atcatctata tggtcgttag
    13381 ctctagtgaa ttaactgaag ctaagaggat cgtccacgag attgacgaaa aagctttcct
    13441 ttcaatcatc aatgtgcatg aagtggaagg gcaaggcttt acttatttga agccacagac
    13501 aagattactg aaaaaactat aagaaaaaag acaaagatag gctatgagga aagattccac
    13561 atccagctga cctttgtctt ttttagtact atactatttt taactaattg ttatgttcac
    13621 ttacccggtt acttttcttt tgtgtctgca aaaggatctt tcggttaact tcatcagata
    13681 atttcaaaaa agcatcccta tctccatctt ctagtgcttg atcgatttga gcataaagca
    13741 tttttagttt tgcctcttct tctttttctt gaaaatatcg ttcaattaat tcagtatctt
    13801 cttcactgac tgaagaatcc caagaagaaa atggattgtc ttctaagata gatagatatt
    13861 ctcttgtctg ccaagcattt tcgaatatac attccacata taaaggcttt ttccaattca
    13921 aacggatttc atgaaaaatc tggtctgtgt ccgtaaattc ttttccctgc aaaaacaatt
    13981 tcatgggttc cccttcaaca gatagatcac tgatctgcag tcctcgatcc gcaaaattcg
    14041 ccccttcaac aaagtggaca ttgcttaaaa tcgcttcatg attggcaaga taattcaaga
    14101 tccaaaaaac ttctcttcgg ctaaaagata catgattgac catccacgtt aaaaaattct
    14161 tcttttcccg tacatcaatt agcatttttc tcacctctct gttaggtcat ctaataatga
    14221 cagtgcctcc atatctcctg gttcaagtgt taaataataa gtcaataatt cttgcgctct
    14281 tttcagctgc ccttcttctc ttaagaaaaa ggcatactct ttcaagaaat ctggttcatg
    14341 tgatagttca tgataagcct gttcatagtg tacagctgca acggtaaagt cttctaattc
    14401 attataagca tgggctaggt tccattctgc ataaggatta gcagtttctt ccatctgatt
    14461 gatcacttgt atcacatctt catatctttc atcatccaag taaagattac ttaaagtaag
    14521 taatgtttca tcttgtttgt ctcctacttc taaagctttc agtaaaagtt cttctgctcg
    14581 ctgtctatca tgcagacgga aagcattttc cgaggccagg tgataaagtt cgacttggta
    14641 aggattttct ttgattcctt cttctaacac tgtttgtgct tcttcaatca tttcttcttc
    14701 ttgaagagct tgtcctagat atagatataa cgattgataa tgcggattaa cttctcgaag
    14761 ttcttccaga tagttgattg cctgctgatt ttctttcaat tgaagattcg taaaagctag
    14821 ctggaacagt cgatcatctg tcctttcttc tttcagtgct tcttctaaag gtacgatagc
    14881 tgcttcgaat tctccttgca tacttaagga ttgtcctaaa cgttcctgca tcgagattcc
    14941 tgaaatttca tttatcccgc ttgccaacaa tgtttcataa accactgctg cctctttgaa
    15001 acgatcaact gaaaaataca attcagctag cgcaaactgg atcaatggtt catcaggaag
    15061 caacccagct gcttctttca attttgcttc actcacttca gggattccga taacttggta
    15121 caaatcagct atcgccaata agctttgcgg atagtaatca ctttgcttat ccactttttc
    15181 caggtattca aaagctaagt cgatctcatt atcttcgatt gcaatttctg ctaacgggat
    15241 gttcagtccg tcattttctg ggtattggtt gatcagttgt tcaaaaatct gttttgcttc
    15301 gatcaaaaag ccaatagcca gcaattcttc gcctagttca gctaatatat ctgctgggtc
    15361 ttcttttaat gctttttcta aaaagatttg tgcttgtgac aagtcttcat ctgataaagc
    15421 ttgcaacatt ttttcgctat ttgtattcat ttcaattccc tcttatctca ctgacgattt
    15481 gttgaaatac cgtcattgtt ctcaataatt ctttttcgtt tggatgttgg tatccgtcta
    15541 ttatacctat tttttctaaa acaagtattt ttttgctttt ttctgccaaa aaaagaactt
    15601 tttccaaata ctccatcttt gaaatctgtt ccagccagtg gattggatag ccaagcaagt
    15661 ccagccacac aaaaaagttt tttagttgga aatcaaaagg atatgcttgg agattccaca
    15721 cgaaatgaaa catcattcct aaaaattttt tcatactagc agaaagtaga tggccatttt
    15781 cggtcagata aaaagcttgt tcaaacagtt taccataatt tgacaggttt tctgcctcta
    15841 attgataaaa atagatcatt tcttcgatca tcccggcaaa cggccgagtc gttaattgct
    15901 ttttatttgg atagttttta tacagatttt gcaaaaaacg atgatcacaa atcattccgc
    15961 aacagataaa agtcaaaaag tcaatctgct ttccgtccac ctgccgctcg ctgattgttt
    16021 gatcataaac gatgcgttct ggcagattga tggtttgcag cactacacga tttggtagct
    16081 gcaaaatcgt ccgctgcggt gttaatgctc ggcttagaga acggatcgat acagggatca
    16141 tccatagtga tgaatcaagg gttgtatgtt tttgaaaaaa acctgccaga tccatgatcc
    16201 cttcatttcc aaatccgatg ataaacatgg attgattttc gggatagcgt ttgacgaaat
    16261 caagcaggtt ctttaattct gttaaatgat tgcattgagt gttggcacaa atataccagt
    16321 cattgtttgc ttgatttgca aataacgggt tgatcttatc tgcaaacaaa tcataatagc
    16381 gctgattcgt taaaaataag attggctgat caatggaaag ttctcttagc tgactgacta
    16441 gcgtttctcc gtaaaacact ttcgtcaacg catcttctac ttgataatca agttccatac
    16501 gcatccctcc tcttcttatt tttattttac cattagtaag caaattctag aaaagataag
    16561 agcaaagctc acctcataac ttgcaaataa ataaaaatta aataaaatac atgtgttttc
    16621 tatgtatgac atacggattc ggaatctctg tctcttattt attccttttc tgctaggaaa
    16681 taaaaagaaa agcacttgta gccctagagc cacaagcgct ttttcaactg tcttatttaa
    16741 cagcgtcttt taatgcttta cctggtttga atgcaggtac tttgctagct ggaatttcga
    16801 tttcttcacc agtttgtggg ttacgacctt tgcgagctgc gcgttcgcga acttcaaagt
    16861 taccaaaacc gattaattga actttttcgc cgttagctaa agcatcttga atagttgaaa
    16921 atacagcatc tactgctgca gttgcatctt ttttagttaa atcagtagct gaagcaactt
    16981 tttcgattaa ttctgctttg tttgccatgg atagattcac ctcctccaca agagatatga
    17041 tagaaatatc atttagttaa aactttctga gtggtccaga agtttaaaaa gaaatattga
    17101 ttaacttcaa tattctgtta tcacgatatc atatgaaccg cttaatagca aggtttttac
    17161 caattttcac atgctttttt tagtcataga aacgtaacaa acgaaactgt ctttttcttt
    17221 tgaaaaaaaa acgtcgatat ggtaaaatgc ctattttctc ctacgaggga taattcggat
    17281 ggacgtccct tcaaaagtaa atgcttttct gatttgattt tctaagaaac gttcataaga
    17341 aaaatgcatc aattcctctt cattgacaaa aacgacaaat gtaggtggtt tgacagcgac
    17401 ttgtgtagca taaaaaatct tcaggcgttt tcctttatct gttggtgttg gattgattgc
    17461 tacagcatcc ataatgatat cattcaacac agccgaagag atacgaagat tctggttcat
    17521 acttacttgt tcgatcattt caggcagacg ttccaaccgt tgtttagtca ctgcagaaac
    17581 aaaaacgatt ggagcgtaat caagataccg gaattcatca cgaatctctt gttcgaaatc
    17641 acgcattgta ttggtttctt tctttacaag atcccattta ttcacgacga taataattcc
    17701 acgaccagct tcatgggcgt aacccgctac tcgcttgtct tgttcccgaa tcccttcttc
    17761 agcattcagt accatcaaaa cgatatcaga acggtcaatg gcacgcattg cacgcatcac
    17821 gctgtatttt tcagtatttt cgtatacttt tccgcgttta cgcataccag ctgtatctat
    17881 cattaagaat ttctgaccac tttcagaaac gaagtgggtg tcgattgcgt ctcgggtcgt
    17941 tccttcaata tccgaaacaa ttacacgttc ttctcctaaa atcgcattga tcaaagagga
    18001 tttaccaaca tttgggcgac caatcaaact aaacttaatc gtgtcgtcgt cctcttcttc
    18061 agtctcttca gagaaatact tcactgcttc atctaaaata tcaccaatcc ctagtccatg
    18121 gcttcctgaa acaggataag gatcgcctag ccctaaggaa taaaattcat agatatcgtt
    18181 tctcatttct ggattatcta ctttattgac tgctaaaatc actggtttat tacttctgta
    18241 taaaattttc gcaaccatct catctgcgtc tgtcacgcct tcgcgtccgc tgactacaca
    18301 aatgattaca tctgcttctt caatcgcgat ttctgcttga tgcttgatct gatccataaa
    18361 aggttcatcg ccaagatcaa ttccgcctgt gtcgatcacg ctgaattctc gacctaacca
    18421 ttcacctttt gcataaatac gatcacgagt tactccagga gtatcttcga caatcgagat
    18481 acgctcacca gcgatgcggt taaaaatcgt agacttaccg acgttcgggc ggccaacgat
    18541 tgcaattgtt ggatttgcca tattatttcc tcctcacaag tttccaatct cacttagttt
    18601 aacgaatgca ttgccaactt tcaagcatag attgtcaatt aaacgaagta tttttattcc
    18661 ttattgaaat actaatcgct tttcaaaaga aaaactgaga caaaagcagc tgctttcatc
    18721 tcagtcacag atacaaaatc aattattttt cagaatcatc ggttgctttt tcttctactt
    18781 cttctttcaa cgcatcacct aaaatgtctc ccatagtaaa tccagtattt tcttctggta
    18841 attcataaga ctcaacattt tttggttctt cttctgaagc tggtttttct tctaaagctt
    18901 tgatactcaa tgcaatacga tgttcttctg gatggatctc taatactttc actttcactt
    18961 cgtcaccttc atgaagcact tcatgtggtg tcgcaatatg tttatgtgaa atttgagaga
    19021 tatggactag cccttctact ccagggaaca cttcaacaaa ggcaccgaag cttgtcaaac
    19081 gtttaactgt tccgtctaat actgtgccaa ctggagcttt tgtatcgatt tctgaccaag
    19141 gtccaggctg tgtgtctttg attgacaagg aaacacgttc ttgttcagga ttgatagaca
    19201 acactttgac atttacatca tcattgacag ccaatacatc acttggtttt gctacatgac
    19261 tatgtgaaat ctctgagaca tggactagac cgtcaattcc gcctaggtcg acaaatgcgc
    19321 caaaatcagt aagacgtgca acacgtccac tgagaacatc tccctcatgg atagttgaaa
    19381 gaatttcttt tttcttttct tctctttcgt tttccactac cgctttatgc gataagatca
    19441 aacgattttc tgatggttcg atttcgatga ttttaaagct caatgttttg cctttatagt
    19501 ctgaaaagtc tgcaacaaaa tgatcttcca ccattgatgc agggacaaaa ccacgtacac
    19561 cgacgtcaac gactaaaccg cctttgacaa catttgtaac aggtgcttcg atgaccttgc
    19621 cctcttggaa atctctttcg atatcttccc aaactttttt agcatctaaa cggcgttttg
    19681 aaagtagata gctgccgttt tctttatctt tgccgatcgt actgataacg actaaatcta
    19741 atacatcacc gacttttact acttcgctga tatcttctac cggcaaagtt gataattctt
    19801 ttgccggaac gactccttca actccagccc cttcgattcc gacaatcact tgtttgtctt
    19861 caatgactaa aacttcgccc ttaacaacat cgccaacttt tacttcttgt acgcttttca
    19921 ttgcgtcttc cattgactgg ttgttctctt gattttgatc aaattctgtc ataacacttg
    19981 tcctcctaac caacattctg ccgtaagtac ggtactgttt ttagtttaat tgattattca
    20041 aaaaaaataa agcgatttcg ttcgttttcc ttgaaaaaac aattgttttt catttttttt
    20101 cttaatttaa aaaagaagat aacctttttt caaaacaaca gcttttattg ctgcaacgac
    20161 ttctggaatc gatttgccag tcgtatcgat acgaacagca tcctctgctt gcttcagcgg
    20221 agagacgtcc cttgttgaat cataatggtc tctttcctgt atctctttcg tcagtgtttc
    20281 aagatcagtc ggaattcctt tttcttggtt ctctttgaaa cgtctttctg cacgctcact
    20341 tacgcttgct actaaaaaga ttttcacttc tgcattcggt aatacagctg tcccgatgtc
    20401 tcttccgtcc atgacaacgc caccgcgttc ccctattttt cgttggacag caactaattc
    20461 ttctctgact tttccatgtg cagagacttc agaaacagct tttgtgacat ctggttgacg
    20521 gatttctaaa gtcacatctt ttgatgctat gaatacatgc tgtccatctt cttgttgcga
    20581 aaaagagata ggatactttt tgatcagcga aactagccct tcttcatctg aaaaagatac
    20641 attgttcgta atagctaaat aagttactgc gcgatacatg gcaccggtat ctgtataaat
    20701 ataattcaat tcttttgcta atatcttggc aacggtactt ttcccagatg aagcaggccc
    20761 gtcgattgca atactgattt gtgtcatgat ataactcctt tttctcagaa aaaaagccgc
    20821 aaagcgcggc tattattatt taattcttaa ttcttgacca gggtaaagca taaagttgtt
    20881 tggatctaag ccattcaatt caaacaattg atcagtggtg atccctgcac gctcagccac
    20941 ttgttttgga ccttcgcctg cttgaacagt cgttgttgaa ccggctgcag ctgatgaaga
    21001 aggtgttgtt tctgctgcat tgctgcttga atcccctgct tgataagttg cctcacttga
    21061 ggaagtcggt gttgtctctg ctgcaatact gctttctgac gttacacctg tatcttgaga
    21121 cacagtagat tcttccgcga ttgtactaga ttctactgtt gaagtctcag ttgactcctc
    21181 ttttgttgta cttgtagaac tttctactac tgatgtcgaa gtttcagaag aagttgctgc
    21241 tgttgcattg ttgcttgatc catttctgat ccagaaataa gcacctgctg gaatagcgat
    21301 acataagacc agtaaaatca aaaatagcga aagaaataat gtatttcctt tcttttgttg
    21361 tctctgagaa cttcttgatg aaacttcatc atctgtatcg tagattggtt gttcccatgg
    21421 ttcttgtgtt tcgttatttt ctgtagattg atgtctatct tttctgctca ctgttttacc
    21481 tcctaaactc tatcgtgtgt attataccat aggaaaaagt gtcttgtcct aaaa
//
LOCUS       DACBYO010000045        21284 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.045, whole genome shotgun sequence.
ACCESSION   DACBYO010000045 DACBYO010000000
VERSION     DACBYO010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.045"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            131..505
                     /locus_tag="IVD26_001636"
     CDS             131..505
                     /locus_tag="IVD26_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP6079601.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="IVD26_001637"
     CDS             complement(619..1248)
                     /locus_tag="IVD26_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP6079602.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="IVD26_001638"
     tRNA            complement(1382..1454)
                     /locus_tag="IVD26_001638"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="IVD26_001639"
     tRNA            1668..1741
                     /locus_tag="IVD26_001639"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            1696..1845
                     /locus_tag="IVD26_001640"
     CDS             1696..1845
                     /locus_tag="IVD26_001640"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079603.1"
                     /translation="MTVNHDVVGSSPTAGVNKAYAKKKKSNHLGFFFFYYYDESSFLF
                     LSRML"
     gene            2338..3666
                     /locus_tag="IVD26_001641"
     CDS             2338..3666
                     /locus_tag="IVD26_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP6079604.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="IVD26_001642"
     CDS             3868..4701
                     /locus_tag="IVD26_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAP6079605.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="IVD26_001643"
     CDS             4717..5454
                     /locus_tag="IVD26_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAP6079606.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="IVD26_001644"
     CDS             complement(5609..6577)
                     /locus_tag="IVD26_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAP6079607.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="IVD26_001645"
     CDS             6809..7642
                     /locus_tag="IVD26_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAP6079608.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="IVD26_001646"
     CDS             7676..8515
                     /locus_tag="IVD26_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6079609.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="IVD26_001647"
     CDS             8541..9101
                     /locus_tag="IVD26_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP6079610.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="IVD26_001648"
     CDS             9300..11021
                     /locus_tag="IVD26_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAP6079611.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="IVD26_001649"
     CDS             11186..12328
                     /locus_tag="IVD26_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP6079612.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="IVD26_001650"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="IVD26_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAP6079613.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="IVD26_001651"
     CDS             14128..14775
                     /locus_tag="IVD26_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAP6079614.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            15168..17813
                     /locus_tag="IVD26_001652"
     CDS             15168..17813
                     /locus_tag="IVD26_001652"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAP6079615.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="IVD26_001653"
     CDS             18123..19436
                     /locus_tag="IVD26_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAP6079616.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="IVD26_001654"
     CDS             19426..20079
                     /locus_tag="IVD26_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP6079617.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20826
                     /locus_tag="IVD26_001655"
     CDS             20134..20826
                     /locus_tag="IVD26_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAP6079618.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20976..21176
                     /locus_tag="IVD26_001656"
     CDS             20976..21176
                     /locus_tag="IVD26_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP6079619.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         7184 a         3551 c         4445 g         6104 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tctggtaatg ttattccatc gcagcaggat
    20701 atgaatttta ccaaaaggat acaaaagtgt ggagaaatga tggggatcac tgtactggac
    20761 cacttgatca tcggacgcaa acgatatttt agtttgagag aagaaggaat gatggaagag
    20821 aagtaagttg ctttcttgca aaaaaaatga agcaagtgta caattatatt gtaattttgt
    20881 ttgggaatag aagttgaaac atctgttgca cctctatcgt acacgagcaa tgttacaatt
    20941 taaattagtg cttttggcac gaggaggata ttattatgga aaacggaaca gtaaaatggt
    21001 tcaacgctga aaaaggattt ggatttatct cacgtgaaga tggaagcgac gtattcgttc
    21061 acttctcagc tatccaaggt gacggattca aaacattaga agaaggtcaa gcagtgactt
    21121 tcgacgttga agaatcagac cgcggcccac aagctgcaaa cgttgtaaaa gcttaatttt
    21181 atctgtaaat caaattgatg gtagacatca atttttacga gagaacaaag cgagtaacaa
    21241 aaatacctgc cacaagagac aatttctctt gtggcaggta tttt
//
LOCUS       DACBYO010000046        20555 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.046, whole genome shotgun sequence.
ACCESSION   DACBYO010000046 DACBYO010000000
VERSION     DACBYO010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.046"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(57..635)
                     /locus_tag="IVD26_001657"
     CDS             complement(57..635)
                     /locus_tag="IVD26_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6079620.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            complement(655..1323)
                     /locus_tag="IVD26_001658"
     CDS             complement(655..1323)
                     /locus_tag="IVD26_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079621.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            complement(1338..2408)
                     /locus_tag="IVD26_001659"
     CDS             complement(1338..2408)
                     /locus_tag="IVD26_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079622.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            complement(2579..3943)
                     /locus_tag="IVD26_001660"
     CDS             complement(2579..3943)
                     /locus_tag="IVD26_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP6079623.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            complement(3940..5499)
                     /locus_tag="IVD26_001661"
     CDS             complement(3940..5499)
                     /locus_tag="IVD26_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6079624.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            complement(5555..8035)
                     /locus_tag="IVD26_001662"
     CDS             complement(5555..8035)
                     /locus_tag="IVD26_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079625.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            complement(8019..8354)
                     /locus_tag="IVD26_001663"
     CDS             complement(8019..8354)
                     /locus_tag="IVD26_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079626.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            complement(8368..9402)
                     /locus_tag="IVD26_001664"
     CDS             complement(8368..9402)
                     /locus_tag="IVD26_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP6079627.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            complement(9492..10172)
                     /locus_tag="IVD26_001665"
     CDS             complement(9492..10172)
                     /locus_tag="IVD26_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP6079628.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            complement(10456..11559)
                     /locus_tag="IVD26_001666"
     CDS             complement(10456..11559)
                     /locus_tag="IVD26_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAP6079629.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(11781..12251)
                     /locus_tag="IVD26_001667"
     CDS             complement(11781..12251)
                     /locus_tag="IVD26_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAP6079630.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            12584..14224
                     /locus_tag="IVD26_001668"
     CDS             12584..14224
                     /locus_tag="IVD26_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAP6079631.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            14378..15700
                     /locus_tag="IVD26_001669"
     CDS             14378..15700
                     /locus_tag="IVD26_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAP6079632.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(15762..16193)
                     /locus_tag="IVD26_001670"
     CDS             complement(15762..16193)
                     /locus_tag="IVD26_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6079633.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(16257..17093)
                     /locus_tag="IVD26_001671"
     CDS             complement(16257..17093)
                     /locus_tag="IVD26_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAP6079634.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            complement(17835..18461)
                     /locus_tag="IVD26_001672"
     CDS             complement(17835..18461)
                     /locus_tag="IVD26_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079635.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(18756..19091)
                     /locus_tag="IVD26_001673"
     CDS             complement(18756..19091)
                     /locus_tag="IVD26_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAP6079636.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(19078..19362)
                     /locus_tag="IVD26_001674"
     CDS             complement(19078..19362)
                     /locus_tag="IVD26_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAP6079637.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(19418..>20555)
                     /locus_tag="IVD26_001675"
     CDS             complement(19418..>20555)
                     /locus_tag="IVD26_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP6079638.1"
                     /translation="FGFVLGLDSFDKKEDGTIERSIDKIKALNEISVVTVPAYDSSNV
                     QVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEKTELRGYEEYIRSQ
                     GEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSNGQGKYPVATNQQA
                     VLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAVNIVQEVKDQLAKL
                     VENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVILNQSGYYHLDTLKD
                     SDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMGDIAQSIFVARRNQ
                     VTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
BASE COUNT         5991 a         4206 c         3545 g         6813 t
ORIGIN      
        1 cgatcttcgt catatcttgc ttcttcacct aactattttc tccctatata acagctttac
       61 gcttctccta atacaccatt caaatataaa tcgatcaatt gcgccacatt tagcggttct
      121 tccacaggtc ttttcgaccg agtgatgtaa ggtgctaaca ctaagaaaaa atgccttgct
      181 gcgatttctt ttgaaatccc atttcttagc acagattggt ttgctgaaaa gatttcttca
      241 aaaggttcac gataattttt cttccataga aagaaaagat gatctcttgt ttcctttgaa
      301 agattgcttt caagatcgtg aagcatcaga aacaaatcga ccagatgtgt ctcaatcaaa
      361 aactgcgcca tttttgtcaa ggttacttga aatcccgttt cgcttgtttg aacgatttct
      421 ctcaaagctt ttccaacatc ttttaagtgg ttttctaaaa ctgccgtata tagtttttct
      481 ttatcaccga aataatgata gagattgggc tgggtgatcc caactttttg tgcgatttct
      541 cttgttgaag tgccgagata tcccttggac ataaacaagt cagtcgcttc tttcaaaatt
      601 ttttgctgtg tatctttgtt gtatcgatgg accatttttc cacctgcttt ttggttattc
      661 tttttctttc aatacaccat cttccatcat aaatattcta tcgcatttgt caatcagccg
      721 tgtatcgtga gtaaccatga tcgttgcttt atttttgtct tttgattctt ttgccaagat
      781 atcgactact tctcgtgcct tttctgaatc caaactagca gttggttcat ctgctagaat
      841 aatggacgga tcattgtaca atgcacgagc gattgcgacc ctttgccgtt ctccaccaga
      901 tagttcttct ggatacttgt tgatcaactt atccacgcca agctgctcaa ataattcgtt
      961 tgcttctttt tgacgatgtt catgtttaat cttatctact aataataact gcttttttac
     1021 tgtcagaaaa ggaaccagat tggaagcttg caaaataaag ccaatttctt taaaacgtag
     1081 tttaacgcgt tcgctttctt tttgattact gaattcttga tcattgataa atacagagcc
     1141 actgctaggc gtctgcaatc cgcctgccaa agtcaaaaaa gtacttttac ctgaaccaga
     1201 aggaccgatg attgcaacaa attccccttt atcgatactc atggttgttt ctttcaatgc
     1261 tttaactact tggtcgccat cttggaaact tttttctact tctttaaatt ctattgcttt
     1321 catgttcttc ctccttctta tccaattgcc ttcaacggat cgatttttac gattgtccga
     1381 acagaaaata gtgcgcctaa cacagctact actaacatca acaagctaat gacgccaaaa
     1441 aacagccaat tgctttggaa tggaaccgca tcaggtagaa caagggatgt tcccactgtt
     1501 cctaatagac caagaagaat accaacaaat gataaaatga atgtttgtgc cactacagaa
     1561 cgcgcaataa atcctcctgt gatcccttgt gctttcatta caccaaagat attaatcttt
     1621 tgcatcgtca gtacataaat gaaaatcccg atcacaatag ccgcaataac gatcaaaaat
     1681 ccgatcataa atccaaaagt caatacttgc gcattatatc caggtaattc attgatgaat
     1741 ttagaaattt tgatctgttc taaatcttca ggtaaattac tgattttacc tctgacaact
     1801 attgcgttaa tccgtgcatt ttcacttgta tcttcttttt cgaagcggat ttcttggtaa
     1861 gcattgatgg ttgtatagag aactggtgag acattgaatt tggcatgatc cgtaaagcca
     1921 gttagtttaa acgtcttgtc actaccagat aacttaactg tatctcctat ggctagacca
     1981 tattcttctt tcaaactaat atcgcctact gcctcatcat cgttatcaaa agcttttcct
     2041 tcaacaagat tgggcatgat gaattgattt ttatcgatac cgaagaagct aacattgatt
     2101 tttccttctt ctgtactgtc tttactagtc acgactccag gtgtttgggc aagatacgcc
     2161 actttcccac cttcgacttc ttctgctatc ttcttagtaa tcatggacat ccctagattt
     2221 gaatttgcat ctttcgaaag cacaatcgaa tctgcctccc acttgtcgac tgctgttcga
     2281 ttatcttgag ctaagccata agctaaccca gtcaaaaaaa ataccaggta ggcgatcaaa
     2341 aacatcaccc ctgcaactaa cgcataacgt aactttgaat gcataatttc atttaatgct
     2401 aaaaacattt aactcctcct cctgaaataa tcattttata caacaatttt atcacttgat
     2461 aaatttttgg cgaatattat gctcaaaaaa ttcttccgct atttcattat atgaattttt
     2521 tattctcgat tgattaatat ttattatatc cccacacaat aaaagaccgt gatatttctc
     2581 acagtctttt atctactcta ttgctatttg ctctcttagc tagtacttta aaagctaact
     2641 cattgaggta gtgaaaacga gaggtgtatt cagacagaaa tccaaaatcc tcaactgcta
     2701 gctgtggaat cgtagttttg tgtttcacga tatccgcaag caggttcaaa tctgataata
     2761 agaattcttg gcttatcagc tgtccgccaa ttatttctaa tgtatccgga tggtagatca
     2821 gctttgcatt tactgttttg ttttcttcgt cgtattgtgg aaatagatca aattctcctg
     2881 aacacgaacc ggtattttgt tccaagaatg gcgcttcatc ttctgtcagc cctacagttc
     2941 ctaaaaagta gtctataatg actgctgctg ttatcttttg tctgaggtcg taagcggttg
     3001 gctgaccact caaagttagc gctactgctc ttgccatatg tacagctcga gtaactaaag
     3061 gtaaaaagag atgccgttta tttttgtcaa aactgactgg gacgatatct ccaatcgcat
     3121 agatgtccgg atcacttgtc tgcagatatt cattgactat cacagtctca tcctcataca
     3181 aagccacttt ttcttttaac aatgtcgtat taggacgagt ttgggcagaa aaaatgacca
     3241 tatctgcctt tattgtttga gacagaagtt gtacggatac tactttctct tctgattttt
     3301 tccaatcgat caagaattca tttggataaa aatttatttg cttagtttgc agctgatttt
     3361 gaaaactgtt gatcatatcc ttatcgaaat atcttgataa aacattcggc atataatcaa
     3421 ctagatgaat aatgtatcct ttatttctca aagcatctgc taattccaat ccaatgtaac
     3481 cagcaccgaa gatcactact tcttttgctt cttttaaagc ggcaagtact tgcttagatt
     3541 gcactagatt tttataggtg tagacatttt cagcttcaat ttgtttatac aaggtgacag
     3601 gagaggaacc tgtcgctacg attaatttat cataggttat ggtctcgttt tttccttctt
     3661 tggatgcgag gatgagctga tgtttgtctg gatcaagttc agttactctc cattcggtga
     3721 tcagttttgc cccactttct tgaagagtcc gcatgttatg ggcaacttca gctaaactac
     3781 gtatctttcc ttttaaataa aggttgattc catttgaaac atagcctagt ccatctttat
     3841 gatcttcatc gatcagtaaa acttctgctt tcggttgaag ttttcttaga tttagggcag
     3901 ctgtgatgcc tgcatgggaa gcaccaatga tcacgatttt catgttttat tcatccttaa
     3961 attcaatttt tctaaataac attcttttaa aaattggttc aaatagggga aatcataatt
     4021 atattcgttg ctagtgaata caaaaacttt agcggacttc tgtgacgggt actctttcaa
     4081 ttggctagtc aaaatgatat catactgctt ttctttctcg tattcgacta aatcatattt
     4141 gatcgtattc agcaattgtt cctggatgat ttctttcacg atatccgcca ttagcctttc
     4201 ataaggaaga tcataagcaa tttgcagacg taattctaac tgcttgatca gcgtccgtaa
     4261 aatagatgca tagcgagcaa ataattcaaa gcgggcattt tcctcgtcta cttcagtaaa
     4321 atcaacaata gcaaatgttt gtctgaccaa tctttcacat aaaaccagga attgtttatc
     4381 ttctacttca gttaaccgct gttttaatcc ttcttggcca aaaatattca tccatcctct
     4441 aaaataggca aaatgagcgt gattttgcat cactgtcaac gcaatctttt gcgaaatctc
     4501 ttctggaaaa acataaaaag agaaatattc ttctatcgat tgtttaaacg ttcgattcaa
     4561 ttgagctact acgtcgtctt tgtatttttc gcttatcaaa aactcctgga catgcgagtt
     4621 atgtgtatct aatgtaaagt tactgatcat gaaaagataa aaaaccaacg tttcattttg
     4681 attccaagga aaggcatatt gaaagaagta acgggtcaaa aatgtatgga ggtccaataa
     4741 aaattgtgtc gtttgaaaca atccaacagg aagattgcta taatctggtt tggatttttt
     4801 cgtacagcgc attcgcttct tcataatgga aagccatatt tcaaatttca atcgtccttc
     4861 ttctgtaata gcaaaactaa actctttttg cagcagatct aaaaaagtgt ttcctgataa
     4921 atcactgtat tcttttttgt tttcaagata gggacgtcca aaccaaaata attggaaata
     4981 aaaataacga atttgacttt ctggaccggt cagccgcccg ctttttattt tcagatgaaa
     5041 ctcatttaaa gaatcattta attccttcac tctgcgagac aaagtagccg aactgatatt
     5101 aagttccatg acaagtttct gccgatcaaa tgagccattt tccaacagat aaagaagtat
     5161 ctgatatttt gtagaatagc gcaagtaaca atgataataa acatcgactg ctgctatatt
     5221 tccatgtctg attaataaaa tattcccttc ttggataaca atttccaatt gtttgatatt
     5281 ttccaagtta gcttgtaaat aaaacagatc ttctttcaag gtagcccgat caactgataa
     5341 gcgggtaagt acgttattaa cggaaacctc tcctttttcc tctaataaaa gttggaaaag
     5401 tttgatttgc cgttgttcat ttttttcaag caaactgaaa agttccaagt ccactccttc
     5461 aagcatttct gattttaaca gcagaagttt ccttctcatc cttgaaaaag aggatctgtg
     5521 acagttatca cagatccata caaattctaa tcacttagct ggttggccca gctgtcagtt
     5581 tccatgtgac catgccttga tacgttgcgc caggttgagc attcgtactg ctatttacct
     5641 ctaagagtaa accatcggta tcgggaaagt caacgagaac ctctccttta gctgttccat
     5701 cactctcata aatcaacgtg ttttgacctt gctgaatcaa ttgctttgat ccagaatgat
     5761 tgaagtataa ttttgttccg cttaattctt gaccttgatc attcttaaat aaagaagtca
     5821 atgtacctgt cagttgccaa ggagacgtgc ttggaagccg agtatcccgc acatcaaaag
     5881 aaaaatcgcc ttttgattca taataacttg tcttcaacgg tttggggaga tcgttaccaa
     5941 atgtaaaatc atctggtaca ttaactaatg ttaattcttg tttggggaca agaattgttt
     6001 tagcagatgt ttggacaact gggttaggaa gcttagcacc atctgctaat gtaatattgc
     6061 tggaaagtac agctgccttt gtcagtatgc tgacggattg taaagaagta tctacagtat
     6121 ttaattgata gttgtaagta agatgaatgg tatctcctat tttgctcaat agatctgctg
     6181 ggacagaaac tccttgttga atgccggtat ctgcgatagt tgtaccattt aattttaagg
     6241 aaccattgat ataagtagta ttttcaggaa gtgagatcgt gatttttttg tcggttatcg
     6301 catccccaga ttttgttaac gtgaatgtca cattttcttg aatcgtatct cctgatagag
     6361 cagacagggg atctcctgtc tcaggttgtc tgctaaggtt ttttagctga ctatctgcac
     6421 tcacagatgg aaaattagcc actgttattt gaggaagagt ggtgattcca gcttgttcag
     6481 actgccattt gtacgcaaaa gacggataca tgttagtaag tacatcgtcc accaagcgat
     6541 aatcaaaata atattgccct gaagccaatg caggtagtgt agaagtagct gtatttacac
     6601 ccccgttatt tgattggatc gtttggaaaa gttgatctgt ccatcctgtc gctaattttt
     6661 gggttccttt cgaataaagc ctgtaatgga tcgaaccctt ttttagttca gttgctgacc
     6721 aattggccgt gacttggtac gatgcagaag aaaggagctt tccccactga ctatcggctg
     6781 ttaagtttgt tggtaaaacc gttccgtcta gcttgtactg ctccaatacc tttaaagcaa
     6841 caggagaaag caatccgcct tgcgcatctt tcccactgta cacgatattg gctgtctgat
     6901 tcaatccact tgtgcttgct ggagtatgag tcagtattgc tccttgtgta acgttttttc
     6961 ctgtaaaata gttgactacg cgatcaaagc gactaaatgg caactgatca aaacgtcctt
     7021 cagtcagccc catcgtcaat gtccgactat tggtagagcc tggaaggttc tggttatttc
     7081 catccacgta ttctgtggta tcagcaaatg tattatattt tcctgttgaa tcacttggtg
     7141 agatgtaact attccacgta tttatctctg cacttgcaga aaatgcatat gctcctggat
     7201 tcaagtttcc gccagttaat ttaggataaa atctacctgc agctggagct aaaatcgaat
     7261 tgaacatacg atcttggata atattattcg aatcataaaa atcaacagaa aaaacggcct
     7321 ttttagacat agaaggttgt aatttaccct tggtcaaaat tttgtttgga ctcgtatcat
     7381 atttatctcc gttttctgtc atcttcgcga cattagctgt aacatcaaat tgaagcggga
     7441 tatcgtccac gttgaattcg cctcgcgtaa taatagcaat aatatctgtc aatagagtat
     7501 ttgtatccca cgaccccatc ccaaaacgca aggtatggct tcctgctgat aataaacttc
     7561 cgctagtaac cttgatgggg gcaccggcaa tatacaagta ggcgttgttc cagtcaattg
     7621 cttttaatac atcactgctt gatacatgtt ccggcaaatt gatgatcgcc acaaatgcaa
     7681 atccttgtgc agtgatattc accaaatcaa gtacatttgt tagtttcaca tggctttccc
     7741 aatgaaaacg gaccgtgcca cctttccaag gatcatttga accatcgttc aaataagtag
     7801 cagtcaattt aggcaattgg ttagccccag ttagttggac aagcttcccg ccattgactg
     7861 cactacgtcc accatttgga ggtacgatat tttcatacgt gtatggatca taagaaatgg
     7921 caggaggcgt tgctccaaca gcttctgccg aaggtgaaaa gataaatata cttaaaacaa
     7981 aaagcgaagt aaaaaagaag gagcgaaaaa atgaaaattt attttgtagc aacatgttca
     8041 tcctcctttt cctttcttct ccataacaac aaccacgcaa gaagccataa ttctatacca
     8101 atgatcaaat aaagaaaacg gatcttttgt tcattcgtct ccgggaatac gccatgttga
     8161 ttagattctt tataaatcgg tagctgtgtc tgctgttttg atgcgccatt gactgaacca
     8221 cttggatgcg gaattggact tagatcataa aatgtaatcg tacctgaact tttggtatct
     8281 gcttggactg gctcttgcca gctgaagaac agcaaacttg caataatccc tcccaataag
     8341 atcgatgttt tcaacgaaat cacctcatca tgttgtttct ccttttttct ttttcttgtg
     8401 gacccacaaa aacagcaaaa tcaaccataa cactagaact gcagcaacca atcctgcata
     8461 aagccatggg aaagattgtt cttgtactgc aaaaacggaa ttttcattta ctttttgtgc
     8521 tttttctttt ttgatcgtaa agttttgtgt aaatcgccat tcattactgt cgcctgattt
     8581 tgctatgatt tctgcgcggt aatcgccggc ttttgcttta tcaccagcta aatcaagatt
     8641 caagtgaaaa ttcgaatttg gtgcaactaa aaatgcatta gacgtatttt caatataaag
     8701 ctgattttca taaaagatct tgctcgtaaa tatcaaattg ctgataatcc taggctgagg
     8761 attttggaaa cgaagctgaa cagttggctt tgcgttgacc tcgtccaaat ctcctgataa
     8821 aagtttcaga tccggttcta tcgtctcttg actttcttgt aaaacgactg cgagattata
     8881 agcaatacga tttttgattt gtgctccttc tgtagcattt tctgtttcag cttcttcttt
     8941 aggtgaaaca tgaatacccg ctaatacacg tcccttaaag ctttttgctg ggattttcac
     9001 ttctataggt acagttgttt ctgcatgtgc tgatacattg atttcctttt tcgcaatgag
     9061 caaaacgtca cggacatcaa acggcaatgt ctcatctaac gttgggtttt tttgactata
     9121 atcgatcgtt ccaccatcac tcgttaccgc cggattgaca gagacctcaa atgttcgttc
     9181 ttcatctgaa gaattgctga taattacttc tagtgtctga ttttgttccg gtgccactaa
     9241 taaatcaaaa taaccgattg ctttatctat ttggttctct ggaaataccg gtttgattcc
     9301 aaagtctcct gctgaatcct ttgcttggct gattgacgga aaaatgaaaa atagacttaa
     9361 aatagaaaaa aacgaaacaa acagtcgttt actttgattc attgtccacc acatcctttc
     9421 aacaaaaact gcggtaaaaa atccttcacc tatagtattt tcaccgcagt ttgttgaatt
     9481 tatttcatac tctatgctac tgggccagcc acgaggttcc aagtcaaatc agccgtgaat
     9541 gttccagctg ctgctttcgg cactttcagt gtgatatttg ctggatcata aacagaaagc
     9601 catgttccca gaccttgatc ttttgctgct gtaaatattg gtgtcgctgc acttgcttta
     9661 ctcaacccag ttacagtttg actagttggt ccagtggatt cgttatctga cgtactttta
     9721 acagtggatg ttccaaaatc taattcagcg ccttgcaaaa cttgtgaacc gtttacaaaa
     9781 tctgaaaccg aaactgtcac gttccaccct tgtgcttggc catctgcacc tacacctcga
     9841 cgatctgata cttggagata aggtgtatcg ttttttgaag cgtctacttg atacgttttt
     9901 gttccgcttt caatctcgtg tgtaccaaat ggcaattcgg gaactacatc cagtgttaaa
     9961 ggacctgtct ggccagttgc tggattttcc ggatctgctg gctctactgg ttttgaagga
    10021 tcagtagggt taagaggctc cacggtattt gttggttcag taaaggtaat atctcctttt
    10081 gaagtcgctt gaccctcagc aaaagctggt gttgccaagc cgcctagaag aagtgttgaa
    10141 agtaataatg tcccaatcat gttctttttc ataataaatc actccttttt cttagtgacc
    10201 taagtatagt agagacagta tgcaaaaaat cctcatgaat tcatccgctt acttgaaatt
    10261 atgacccttt ttgtataaaa gagaaaaaaa caataaaatc gtttacatga atattcttcc
    10321 ttttttatta agtatgaaaa aatatttcaa ttttattttt tcgtttcaaa ttattctatt
    10381 agtgacatcc ttgaactata aaaataggag tacggcatca tctgccgcac tcctattttt
    10441 ttcgtcattt gtttcttaaa taaaacgatt ctcacgcaat tttatttttt tgatatcttc
    10501 tactgtttgt gttccagcta attgcatgac catttccaat tctgttttaa agaaatcaaa
    10561 cacttgatgg actcctgtac ttcctcctaa agacaatcca taaataacgg gtctgccaat
    10621 agcaacaaga tctgcacctg atgcgattgc tttgaaaaca tgctgtccgc gtcgtacacc
    10681 gctgtcaaac acgattggta cacgtttatc tactgcttct gccacatatt gcaacgaatc
    10741 aaacgctgct ggaccaccat ctagttgacg gccaccatga ttagataccc agattccgcc
    10801 agcaccagat tctaatgaac gatagacatc ttcttctgac tggacacctt tcacatagac
    10861 tggcaaatca gaatgagcag caataaattc tacatctttt ggactaagct tctgtttgga
    10921 agatttgtac acagcatcca tcgtttggcc tactcctgat tgataagcct gaacgatcgg
    10981 cattggcagt gggaaggtaa acccatttct gcggtctgtt tcacggtttc cgccaactgt
    11041 tgcatccgct gtcaatacga ttgcttttgc tccattacgc ttggccactt caagaatatc
    11101 caaattgatc ccatcatctt tgctcatata aaattgaaac cattgcggtg ctttctcccc
    11161 gcctgcttct cttatctctt ctaatgtaca agaagcgtaa gaacttgctg tatagatcgt
    11221 cccaaaatct gctacacctt ttgcagaagc tttctccgcc ttcacatgag ctaagccatg
    11281 agcagcaact ggtgccatga tgattggtgc agtcagcgtt tctttgtcaa aatgtgtagt
    11341 tgtatcgggt aattctacat cttttaatac atgaggaata atcagctgat gattgaatgc
    11401 ccgttcattt tcttgataag taaataagtc gccagcacca ctgctgatgt aaccataacc
    11461 accagctgga atcacttgtg aagcggctat ttctaaatct tccatattga taaaatccac
    11521 tattccttca tttgtacctg cttgatacgt tttttccatt tcaatgcctt ccctctataa
    11581 aaaattgaat gaataatatg atagcgttta cacactttat attactcttc cgtattgata
    11641 caggcaaata atctgtttac atttcagtca ttccagttgt tactactctg aaagaaatgt
    11701 ttagaacaca aatagataaa aaacgatggg actttgacaa aagtcgtgtc aaagtccctt
    11761 ttacgaaata ctgtggatgc ctattgaaat aagtgcgggt tgtttctttg tatttcaatc
    11821 gtttcttgcc attcttcgtt taattttgga ttaccgtttt cttccttgaa cgcataaggt
    11881 cccaatccaa aaagctcagt tagtatttga ttcacgattc catatagctc ggtgtgatcg
    11941 gacacatgat tattgaagat catctcatta tcaccacgtt tgaatctcac attcgggctc
    12001 tcatgatgaa cctctatgca gttttcccct ttttttaact gacggatttc tgaaaacatc
    12061 tcataaatat cttctccaat aaaaccttca gcaagcgcca gactgtccac aagaccgcct
    12121 actgtcaact cagagattat cgctttgttg gcaccaagct ttaatgtata gcttgttgct
    12181 tctactacgc cgcatgcatt gcaaccacct tctgatagtt cgctttttct gatcaattga
    12241 acttctttca ttttctgttc ctcctcttag ttttctactt atgtattttt tatcacctga
    12301 cgtaagtgta ttttatcgtc acgatcacgt gatttattct tcagagattc tatttatcta
    12361 tctaacatat cctttattct tctacttttc tttctttagc atataagaga tacgcatagt
    12421 aatcaagcaa ggattgttga tataaaaaga acaaataccg ctattttgat ttcttttgac
    12481 tctattactc atataaataa aatttattat acctgctctt tttgactata tcctcatctg
    12541 actcctatac ttcgtttgta ttaaaactta ggaggaatca ttcatgctta cagggctaaa
    12601 cttattaaat aatccttttc taaataaagg aacagctttt acaaaagaag aacgggcaaa
    12661 atacggaatc actggtatgc ttccaagtac tgtccaaaca ttggaacaac aatctgtcca
    12721 agcttacggt caatacttaa gcaaacagac cgatttggaa aaacgtatct tcttaatgaa
    12781 tctattcaat acgaaccgga cattgtttta taaattgatg ggcgaacatt tagttgaatt
    12841 catgcctgtc gtttatgatc ctgtcgttgc ggattcaatc gaacaataca acgaaatttt
    12901 cttgaaacca caagatgctg catttctttc aatcgacgaa ccagaaaata tcaaagcaag
    12961 tttgaaaaac gcagcagatg gacgcgacat tcgtttgatc gttgtgacag atgcagaagg
    13021 aatcttaggt atgggtgact ggggtgtgaa cggtgttgac atcgctatcg gtaaattgat
    13081 ggtctacact gctgcggctg gtatcaatcc tgcacaagtc ttgcctgtat caatcgacgc
    13141 tggtactaat aacgaagaat tattgaataa tccattatac ttagggaatc gtcatgctcg
    13201 tgtagaaggc gaaacttact acgaattcat tgatcaattc gttcaatcag ctactgaatt
    13261 attcccagaa ttgttattac attgggaaga ttttggacga ggaaatgctg caacgatctt
    13321 agaaaaatac gaagataaaa tcactacttt caatgatgat atccaaggca caggaatcgt
    13381 tgtactagct ggtgtattag gtggattgaa tatatcaggt gagcaattga aagatcaaac
    13441 gatcttgaca tttggtgctg gtactgctgg tgtaggtatc gcaaacatcc ttttagatga
    13501 aatgatccgt caaggtgtac ctgaagaaga agcacgccaa catttctatc aagtagataa
    13561 acagggttta ttgtttgaag atacaaaagg attgactcct ggtcaaatcc cattcgctcg
    13621 taaacgctca gaattcacta atgctgatga attgacaaac ttagaagcag ttgtaaaagc
    13681 aatccatcca acgatcatga tcggtacttc tacccaacct ggagcattca ctgaagaaat
    13741 cgtgaaagaa atggcggctc ataccccacg tccaatcatc atgcctttgt ctaatccaac
    13801 aaaattggca gaagcaaaag caaaagattt gattgaatgg acggacggaa aagctttagt
    13861 tggaacaggt atccctgctg ctgatgtgga atataacggt gtaacttacc aaatcggtca
    13921 agcaaataat gcgttgatgt acccaggttt agggcttggt ttgattgctt caacagctac
    13981 acgagtaaat gctgaaatca tttctcaagc tagtcgagca ttaggcggaa tcgttgatgt
    14041 aacaaaacca ggagcagcta tcttgcctcc agtagcaaaa atcactgaat tctctcaaac
    14101 gattgctgaa actgtcgcaa aatcagttgt tgcacaaaaa ttgaatcgtg aagaaatcac
    14161 ggatatcaaa gaagctgttg aatctgctaa atgggttcct gaatataaat ctttagaaga
    14221 ttaagattgt tatagtaaaa gaacatacag aaactttgta tgacgtctaa aaagaaaaaa
    14281 gcgactgcgg caaaacagca gccagccaac tactgctctt ttgccgcttc tctttggctt
    14341 ttttcatacg atacagaata agaaaggatc tgtaaaaatg gcacaaaaaa caacaaccgc
    14401 aactgcagtt gaggaaaaga aaaaagaagg gttttggtca acaaaaatta ccggcgtaag
    14461 tttgcccctt tatttgatca tggtccttgt cctgatcatt gcaatggctt taggaaaatt
    14521 accgacgaat atgattggcc caatcgctgt tttggtcatt ttcggtaatt tatttcattt
    14581 tatcggaaca aaaatcccta tcgtcaaaag ttatttaggt ggtggctccg tttttgcgat
    14641 ctttgcctct gccgcgattg ctacatttgg gatcttacct gagtatgtag taaaatccac
    14701 agaaaacttt gtcagcaata tgggcttttt agacttttat attgctgcct tgattactgg
    14761 tagcatcctt ggtatgaacc gtaatctatt gatgaaagct tctgttcgtt ttattcccgt
    14821 tgcacttatt tcaatggtcg tctccttttt tgccgtagga ctcgtaggta tgcttatcgg
    14881 aaatggtttt gcaaattccg ttttatatat ctcattgccc gcaatggctg gtggtgttgg
    14941 agccggagct gtacctttat caacgattta tgcaaatgtt ttaggtacgg acgcttcttc
    15001 tatcatttcc cgcctgattc ctgcgacagc aatgacaaat gtcctagcta tcattggtgc
    15061 agcgttagtt gctcgtgcgg gacaatcaat gccaaaattc aacggtaatg gtaaattaat
    15121 ggaaaaaggc gaccttggcg atggaaaacc tagaaatgta aaaccttcca ttccacaatt
    15181 aggtgtcggt ttgatggtat cattgacttt cttcatctta ggacaaatct gtaactattt
    15241 tgttcctaaa gtccatgctt acgcattcat gatcattatc gttgttatct gtaaaatcgc
    15301 aaacctatta ccagaatatt acgaagatgc agctatcatg ttcaacaact tgattgtcaa
    15361 aaacttgaca gcagctgttc ttgccggtat cggtattgcg ttattgaatc taaatgtatt
    15421 ggcttctgct ttgacatggc aatttgttgt cttatgtttg acaagtgtta tcgcgatttc
    15481 agtagtttca ggatttgtcg gtcgtttgtt tggtttatat ccaatcgaat caactattac
    15541 tgctggctta tgcaacaact cgatgggtgg tacaggaaat gtagctgtct tatctgcagc
    15601 taatcggatg gaacttattg cttttgctca aatgggcaat cggcttggtg gtgccatcgt
    15661 tttgatcatc tcaggtttct tgatgcaatt actttcttag tcaaaaaaaa tacctgatca
    15721 tcaagtatcg gcttgatgac caggtatttt ttgataaaaa tttacaggat tttcaaaaat
    15781 cttttttgca ttttatcgga atgataaccg atgcgttcat aaaatcggtg tgcttctact
    15841 ctgtattctg cagaattaag tcttattgct gatattcctc gtcttttcgc ttcttctacg
    15901 ccagtcatca aggcctttcc gattcctctt ttttcagcat gtttagacac agcaagtgcc
    15961 ataatattga acatcggatc gctgaaaatc gattcatagg actccgcttg tacatagcca
    16021 gctgcttttt tagaagtagg atcttcatag accaagaaaa aatttttttc tggctccttc
    16081 aacagtttct tcatttgtct caccgtaacg gttaatggta catcatatcc taattgttcc
    16141 gcattgattt ctcgtagtgc ttctgcatct cctaaacgca tttcccgcaa catccaaatc
    16201 accagccaat ttttattttt ttaaatgaat ttttttatca cagtatactc cttttttcat
    16261 ttagaacaat atgtttcagt gattttgact tgcgttagtc tagattctcc taatgtttgt
    16321 aagatgacaa aggcattgta acaattgacc aaaagaacca cgaggacaat tacttgaaaa
    16381 ataaaggtca ctttttttgg agacaaaacc ctgctaaatc ttgctcccca caaacctcca
    16441 ataacagcag cggggataac ataaaacaac atagataaat caaagcgcat aaagctactt
    16501 gttaaagcaa tcgttaccaa ttttgccagt tgagaaaaga aaatcgtaga tagagaatat
    16561 agtgttgctt cttttattgg caatgcaaac atcagcatca acaaagaaac attgactggt
    16621 ccaccaccaa tacctaaaaa actagctaaa aagcccagaa cccccccaca tataaggtac
    16681 caagtccatg acgtcaaatg aaattttggc tgatgatgct tggtgtagaa gaacgcaaaa
    16741 accaaggtca ataccgtcaa aaaaatttgg atcagctgca catgcttctc gttttcaaat
    16801 aactgtaaaa aaacttcgaa tacaatgttg ccgactactc ctccaacaac agctccacta
    16861 gatacccaac cgacaatctg ccaattcagt gatttcccgc ttgatacttg tcgcacagtc
    16921 gaaacaatgg acatcgtgaa taccgcaact gttgagtaaa aagaaatccc tgcaacagaa
    16981 tgggcgccga taagatcaag aatcggtttg atcaacacgc ctccacccat cccggaaata
    17041 gcgccaactg tgttcgccag aacgatcacc acaaaataaa tcagaccaat catcttgtat
    17101 ttcctttctc ttgtttatat cttttagcga ttgttactct tttcttttat tatacagtaa
    17161 aagaaacaaa cgaggcttcg aaagcttttc tactttttaa ggaaatttag tgctaaacga
    17221 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagc
    17281 tcctcataat tttcgtttgg ttgaacttat taccgcagat gcaagctttt gaacaccgtt
    17341 taagaaagag gtcgtgagcc tgccgttcag ctccgagtca caaggaacaa tttcaaaaaa
    17401 cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttggca ggagaacacc
    17461 gtttaaggaa gagactgtga agtcaacgtt ttgacctgat tattagagaa acaaatggca
    17521 aaatagttct tcatatttcg ccgtttttcg agcgaatgcc gaggggcagc tgattgaaca
    17581 tcgtttattt ggaaaaaggg attgtgacaa gacgtttgtc acaatccctt tttttatatc
    17641 ttattaattc attcttttgt tctattcttc ttcttccgcc atgaatgaga aacccatatc
    17701 aaagaactat aaaggttatc aaaacagcgt ttatgactaa atgaattaga gttatctatc
    17761 actatttttc aagcgattta aaccaaatgg catacaatat ggcatacaaa aacttcaata
    17821 agccgtgggg gtttttaaat ttcttcttgt tctttaaaat caatgagtgg agctacataa
    17881 tttgaatcca ctttttcaaa cgtcactttt tgcatcgacg aatgttttct ttcccaagat
    17941 aacgtaaata gatttgactc tggacttata aagtctactt caccttctag tattactttc
    18001 ttatgcaaat attcctctaa taaatataga cttgctaaag catacaacac attttccaaa
    18061 tttgcttcct tataatttga agaacgacca tgttttactc tgttatatat tttccaccaa
    18121 tctggtgtat cttcaggcca cccatctcca aaaggtttta gtgaagtcaa tgttaaagaa
    18181 ttcataaccc taacaccatt atccaaacac attaattcgc tagatttaat aacagcttta
    18241 aaatcagtta tgcttttatt gctactgcta tcaaatccgc aaagttcttt gaaaataatc
    18301 tcacactccg aaccaatcgc tagtagtagt ttttgatatt caatagagaa tgttttgaaa
    18361 ttattctcat cgagcatcac aaaatctgtg gtattaataa actcattttc taaatgtaga
    18421 taatacttcc aataaaaatt tgtaaactct gctttgtcca ttaaatcacc tcttttgaat
    18481 tataacaaaa aaaacacgtc cacaacagac gtgttctttg atttctacac aatcagcttg
    18541 ccaaaaccat ccaatcagtc ctagcatgcc tgtattaaaa ttgaacgttc atcatctatc
    18601 atctttctta gtccagcatg tttgcaacca cacctacaat tttcagtcca acaatagatt
    18661 tcgactagct aagtcttgca aaattcaggc agctaaccct tcatttacta ccttaattat
    18721 actaaatacc cacaacgttt acaagtgtaa tcattctaag aaatctgttt agctatgatc
    18781 gttgtataat ctttaaacgc cgttccttca ttgattgaaa taattttata actcttgttt
    18841 ttccaagcta ctttcatatc gtttgttagt tcataatctt gatcgtatcg aataataaac
    18901 gtcaacgttc cttcaagaat ggtacctaca ctagcaagca cgtcttttag catttgtgaa
    18961 cgcacattag cccaacattc aaatacagtt tcttcactat ccaccatctg cccatcttca
    19021 tcttttaccc gttttgtctt tttaaacttg actctctcag tcaattcatt tacattctta
    19081 atgattggca taataagcac ctctcatttg ttgtactaat gcttgtaccg ttactggtat
    19141 ccgttcgctg ctggcttctt gacggttcaa ataccaatgt tgagtaagta atgacaccgc
    19201 caaatcaaat tgctgataat tatccatatc tttatccgtt gcgctactat caatagcact
    19261 ttttatatat tcgcctgctg tatcaatcaa ttgttgaata aagtcatcat caatagtgtg
    19321 atcgatccgc atactttttt ttatgctatc caaaattacc attttatctc tcctaatgaa
    19381 aaaaaggcag tgggataaac cgccgcccaa tatttttcta tacttttggt gttacaactg
    19441 gcgtaaactc aatatacact gaagcatttt gatcaatttt cttataatcg ttgcgaacga
    19501 tcactgcaag tccttgtgag tagtaatcga atttttccca ttgagtcgtt acttgatttc
    19561 tacgagcaac aaagatagat tgtgcaatat cccccataat catagggaat gttccagctt
    19621 taggattggc aaacaatgta tctgcaatca atactactgg cataccgaat aatgatttac
    19681 cactaggtgc tgtcacatcg ggttgtaaaa tgtaacgtcc atctgaatct ttcaatgtat
    19741 ctaggtggta atatccgctt tggtttagaa ttaccatttt atttaatgct gggtctaatg
    19801 ccacattgta tagttgtttc aaatcgtcca acgtagcagc cgttttctta gtgaatgttt
    19861 ttaataaatc catgatatgc ttattgtcag tgttttctac caatttcgct aactgatctt
    19921 tgacctcttg tacaatattc actgctgaat cttccacaac ctcatttgat aaggcaatct
    19981 taccagcacg agtttctact ttataatcaa ctgaagtaaa catttcagcg tcaatatcac
    20041 caatttcagc aagttcagct tttgttgcta acactgcttg ttggttagtt gctactggat
    20101 atttaccttg tccatttgat actgttttta ctgttgcata ttgagctaag ttataatttg
    20161 aacgtttcaa atcaaagact tcaccgatta cttcttcggg aacaactgcc gctgcattta
    20221 cagtagtgac tccatcacgc acttcgcctt gtgaacggat atattcttca tacccacgca
    20281 attctgtttt ttcgttatcg attaaagttt tttccatgtt attactctcc ttttgtgctt
    20341 tagaagtgga ttctaagcta ttgtttgttt gttttgcttg gttgttactc ataaacgatt
    20401 cgtaagaacg cttatttact tggacatttg atgaatcata agcgggaacg gtcacgacac
    20461 taatttcatt aagtgctttg attttatcta ttgatcgttc aattgtgcca tcttcttttt
    20521 tgtcgaatga atctaatcca agcacgaacc caaag
//
LOCUS       DACBYO010000047        20184 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.047, whole genome shotgun sequence.
ACCESSION   DACBYO010000047 DACBYO010000000
VERSION     DACBYO010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.047"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            210..1016
                     /gene="proB"
                     /locus_tag="IVD26_001676"
     CDS             210..1016
                     /gene="proB"
                     /locus_tag="IVD26_001676"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAP6079639.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1013..2260
                     /locus_tag="IVD26_001677"
     CDS             1013..2260
                     /locus_tag="IVD26_001677"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAP6079640.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGNGQIRE"
     gene            2336..2680
                     /locus_tag="IVD26_001678"
     CDS             2336..2680
                     /locus_tag="IVD26_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079641.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2797..3123)
                     /locus_tag="IVD26_001679"
     CDS             complement(2797..3123)
                     /locus_tag="IVD26_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079642.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3496..4698)
                     /locus_tag="IVD26_001680"
     CDS             complement(3496..4698)
                     /locus_tag="IVD26_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6079643.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4815..5330
                     /locus_tag="IVD26_001681"
     CDS             4815..5330
                     /locus_tag="IVD26_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP6079644.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5529..5975)
                     /locus_tag="IVD26_001682"
     CDS             complement(5529..5975)
                     /locus_tag="IVD26_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAP6079645.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6022..7500)
                     /gene="msr"
                     /locus_tag="IVD26_001683"
     CDS             complement(6022..7500)
                     /gene="msr"
                     /locus_tag="IVD26_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAP6079646.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7854..8483)
                     /locus_tag="IVD26_001684"
     CDS             complement(7854..8483)
                     /locus_tag="IVD26_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP6079647.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8467..8931)
                     /locus_tag="IVD26_001685"
     CDS             complement(8467..8931)
                     /locus_tag="IVD26_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6079648.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9418..10686)
                     /locus_tag="IVD26_001686"
     CDS             complement(9418..10686)
                     /locus_tag="IVD26_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAP6079649.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10917..11654)
                     /locus_tag="IVD26_001687"
     CDS             complement(10917..11654)
                     /locus_tag="IVD26_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6079650.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11721..12290)
                     /locus_tag="IVD26_001688"
     CDS             complement(11721..12290)
                     /locus_tag="IVD26_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAP6079651.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12418..13290
                     /locus_tag="IVD26_001689"
     CDS             12418..13290
                     /locus_tag="IVD26_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6079652.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13632..14504
                     /locus_tag="IVD26_001690"
     CDS             13632..14504
                     /locus_tag="IVD26_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6079653.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14501..16459
                     /locus_tag="IVD26_001691"
     CDS             14501..16459
                     /locus_tag="IVD26_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6079654.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16710..17561)
                     /locus_tag="IVD26_001692"
     CDS             complement(16710..17561)
                     /locus_tag="IVD26_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6079655.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17684..18151
                     /locus_tag="IVD26_001693"
     CDS             17684..18151
                     /locus_tag="IVD26_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAP6079656.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18414..18896)
                     /locus_tag="IVD26_001694"
     CDS             complement(18414..18896)
                     /locus_tag="IVD26_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6079657.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18996..19859)
                     /locus_tag="IVD26_001695"
     CDS             complement(18996..19859)
                     /locus_tag="IVD26_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6079658.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6069 a         4157 c         3662 g         6296 t
ORIGIN      
        1 actactccta ttctaacata tccgaggctg taaaagactt tctttacaaa ttcttcaaga
       61 aattctgcta tcttaaagta aaccattaat tcgttctttt tccaaacgac tacaagttgt
      121 acaaaaaaac tattttttac atgactttac tcgtcaaaac aagtagaata gaacgaaatt
      181 aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga aattaaaaat gcaaaacgaa
      241 ttattgtcaa agtaggaaca agtacattga tttatcccaa tggaaatatc aatcttgcgg
      301 caatcgatca gttagctttt gtcctttctg atcttagaaa tcggggaaag gaagtgatct
      361 tagtctcatc aggagctgta ggcgttggta tgcataaatt acatttgtca gaacgtccga
      421 ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca agccgaactg atgaatatct
      481 ataatcaaag attcagtgta tataatcaac agacggcaca gatcctcgtg acaagagacg
      541 tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac attggaacag cttttgatta
      601 tggacacgat ccctatcgtg aacgaaaacg atactgtagc agtggatgaa ttagatcatc
      661 tgacaaaatt tggcgataat gatcagctgt cagccatcat ggcaaaactt gtcgcggcag
      721 accttttgat cgtcctttct gatatcgacg ggttttattc agataatccg actacaaatc
      781 ccgaggctca gatgtatcgc tatatcgata aaatcgatga aaagattctg gcacaagcag
      841 gtggtgctgg tagcacattt ggaacaggcg gtatgcagag taaattaaaa gccgcttcta
      901 ggatatttga agcaaacagc gcaatgattt tagcaaatgg aaaaaatccg gcaattattt
      961 ttgatattct tgcaggaaaa gaagtaggta ctttatttaa ggaggacttg aaatgactga
     1021 cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa caactagcac ttatgcctac
     1081 aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc atcaaaaaga atcaacaagc
     1141 gatcattgaa gcaaatcata aagacttaga aaaagcagtc gaaaacaata tcagtgaaac
     1201 gatgcaagac cgcttgcagc tgacacctga gcgaatcaat gccatggcta cagagatcga
     1261 aaaaattgct tcgttagacg atcctattgg aaaagtagat gagatgtgga cgaacaccga
     1321 cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg accggcatca tttacgaatc
     1381 tcgtccaaat gtcacgacag atgcagctag tctagcattc aaatcaggga atgccgttat
     1441 ccttcgcggt ggcaaagaag cattcttctc gaatcaatta ttagtccaat tattgcagca
     1501 agtactggtc agtgctggcg aatctcctta tgccatccag tttgtcgatg atacttctca
     1561 tgaaactgca ggacagttga tgcgattgac agaatactta gatgtgctga ttcctcgagg
     1621 cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg gtacctatca ttgaaacagg
     1681 tacaggaaat aatcacgtat atatcgataa agaagcacag ttatctatgg cagtgaacat
     1741 catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac gcggcagaaa cattgctgat
     1801 ccattctgag atcgcacctt ttttcttgcc agctattgaa aaagaactgg tagaacacgg
     1861 ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta gagacggctg ctttagcaga
     1921 agacacagat tgggatactg aatatctaga ttatatcctt gctgtcaaag tggtcgattc
     1981 tttggatgaa gcaattgcac atatcaatcg gcataatact aaacattcag aaacgatcgt
     2041 gacagatagt tatgcggcta gtcaacgttt cttaaatgaa gtggacgcgg cggctgtcta
     2101 tgtcaatgcc tccactcgtt ttacagacgg atcggtattt ggttttggtg cagagattgg
     2161 tatctctact caaaagttgc atgcccgtgg tccaatgggg ttaaatgaat taacttccac
     2221 aaaatatatc atttatggca atggacaaat ccgcgaataa tgtttcgtgt gaaacattat
     2281 tcccgccttt tgcctttttt ctgtaaaggt tctatccaac tagaaaggtg tcaatatgtt
     2341 tgaaatttta atgatttttt ttatttacct tatttctctg aatatcgctg cttttctggg
     2401 agtcggtatt ttatcccttt tctttcaatt caaaaaacga agcataggga gtcaacggga
     2461 aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg ctggttacac gcttgcacat
     2521 tagttacatg gttgcattat gcttattagc gacaatcaat tactattctt ttttcgatca
     2581 ttcaatcgct tatacgatta cgctactgat tgctgggatt tttcacttat cttataaata
     2641 tcagctgaat aaaaaccact tgaatcggac tttccgctaa aaaatatccg tacgataagt
     2701 agagtgcctt gaagatcggc aaaaaactgc cggacttttt agaggctgtg acaaagattt
     2761 tgtcacagcc tctttttcca tataaacggc gttcgcctac cagctgcctg gtaaatctgt
     2821 ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg ccatcataat aacgaagcag
     2881 ctcatccatg gacaagttca tcgttttttc tttttcttct tccgctgatt cagccagtag
     2941 ctgttcccga tacacctgat acataccagc tattttttgc tgcatcgctt ttctagtttc
     3001 accttccgca ttgattattg gcaattcttt gatatagcca cgataaatca accgatcatc
     3061 tgaaaattca atgggtaatt caacgagtgt caacccgact tcctgaaaat attcttccag
     3121 catctattat ccccccattc tttttcttaa atgaatttta gcttacctac tgaaaatttt
     3181 ccagtttcat tattttgaga aaaaaaggga atgtgacaaa aatcgtgtca catccccttt
     3241 ttccgaataa atggtgttct tctgccaact cctcaatcat aagtcacaat attcaacaaa
     3301 catgagaaac tgttttttga aattgttcct tgtgattcag agttaaacga cagtctcaca
     3361 acctcttggt aaacggcgtt caaaagcttg catctgcggt aataagccca accaaacgaa
     3421 aaatatgaga agctattttt gtttggctgt tcttatgact tgatgcagga cagctttttc
     3481 acaacctctg atttcttatt cttcttcatt tgtagcaaaa taattacggt gataaatgat
     3541 acaacataca ctgataagaa caatggcacc tgcaaaataa aacgcatagc tttcaccaat
     3601 atgttcacca atcacacctg caataaatgg tgctaaagct ccaccgaaaa agcggacaaa
     3661 actatagctg gacgaagcaa cgtttcgttg cagacctggt atttccatag caatcgtcgt
     3721 caacagtgta ttgataattc cttggaaaaa tcctgctaac acaatgctga tcggtacaag
     3781 gactggcata gaagttccag ctcctaataa cagcaaacaa ataatgaata agacaaatgc
     3841 tgctaaaatt gtccgataag tcgtaaactt ccgctcaaga gccggtgcaa cgaaaatcga
     3901 agcaatagcc agaagcacac cccagccaaa aaatacaaaa ccgacttcta attcagaata
     3961 gccaatcaat aaaaatggcg catacgcaag taaagtaaag aatccgaaat tatataacaa
     4021 tgcgattagt ccaactgaac gaagtttatg attgcttaac gctttgacac cttcccaaag
     4081 gcctactttt ctctttggtt tctcagtttc aggtaaaagt accgctaggg ctataaaacc
     4141 gcaaaacatc aaaaatgcta ccccaaaaaa tggataacgc catgaaccac tgcccaagac
     4201 cccaccgact agagggccaa cagccattcc gcagccaagt gctgcttcat acatcatgat
     4261 tgctttttct gtgttaccaa ctaaaatact gacgatcgtt gctaaagcag tagagacaaa
     4321 taaagcattc ccgacacccc agccggcacg taacccaatc agcattccga tattcccaga
     4381 taatccgcca agaccagcga atacaacgat gataaacaat cctgtcatca atgttttttt
     4441 caaaccgatc cgactagata agaaacctgt aaatagcatc accacaccag tgactaacat
     4501 gtaactagta aataacaggg tcgtttcagc tggcgtagcg tttaactgtg cagcaatcgt
     4561 ttttaagatt gggtctacta gacccactcc cataaaagcg atcatacagg tagctgctac
     4621 aactagcgct gaacttttcc cctttgtttc ttcatttgtt tgttcttgta tatctatttg
     4681 attctccaat atttccatcc ctttctctct attagcatca tacatgattt attttacatg
     4741 taaatatgca catgtaaaac gtggaaactt tactgtgata taataaagaa aataagacga
     4801 gaggtaggat ttttatgaat actttagcct atatattatt atgcgtgctt ttatccaaac
     4861 cacgttctgg gtatgaattg aagcagctga tcacaatttt ttgggaagcc catcacagtc
     4921 agatctatac aacgcttgcc aagttagacc agcagggtta tgtgaccgtt ttggacaaag
     4981 acgagcactc tcaaaaaaag atctaccact tgactgatga aggacgtgct cttgtagagg
     5041 aatggatcaa agaggaaact cccgctccta cgcaaaaaga tgaatttcta gcaaaaatct
     5101 atgctttttc gacgctcgat aaaacaacag ctactggact gctattcact agagaacaac
     5161 agctgaacaa aatcatgcaa aaaaatcaaa aaaaattgaa tgacctctcg ctagacaaga
     5221 aacaagaatt tggacgttat gttgtgatcc agcgcagaat tatgctttgt cagcaggaac
     5281 tccaatggtg tcagcaagta agagaacaaa tgcagcagtt ttttgagtaa gggataaaca
     5341 gaacctttct agaaatatct attgaagagc aaattatctt caataaaaga gcaatacagt
     5401 tggaaaagaa aaagcgatcc gaacgacagg ccaaaaccta tcgttcggat cactattttt
     5461 ctagaactgc attcaagaga ctatgacaaa aagcatgcca aggccttttt tcaaataaca
     5521 gtgttccatc attcattact ttgaattgct tttagcacac ttcttgaaag cgggccaacg
     5581 atgatcaact gcaacggtaa agcggcaatc acattcattt tccaagcatt catataagca
     5641 gagaataatt gatcaggtat tccttgttcc atgatcacac cgaataaaga catacatgtc
     5701 accattccta aaaccatcaa gcatgaaata gttaagatca tttggacctt gctttctgga
     5761 tttactggta gtttaaaggc aatttttttc gccagcacac cgatgatgaa gacatccaaa
     5821 atgaaagcca ccacgaatcc aggcactaga ccaatcaaca aacttgataa atgaagatct
     5881 tgatgcagcc ataaattata cgcgctcatc cccaagacca tcaaaaaaca catcattgtt
     5941 gtaaaaatta ttccttcttt tttatttgta ggcaatctgt accactcctt taaatttgtc
     6001 acgaaaatca tcgtagcaca tttaaaaatt tctcgtaagt acttttttta ttttctgccc
     6061 ttttatttca taaacttcat cagccgtacg ctcgacaaag taagaatcat gagaagtaaa
     6121 caaaatcgtt cccggatata tttgcattag cttctctaaa gcttcgatcg ttgccatatc
     6181 aataaaatta gtcggttcat ctaacagcaa cacattactt ggcttagtaa aaagcaaagc
     6241 aatcgtcaga cgggtcgctt ctcccccact taatgtacat aacggtttcg tcaaagtttc
     6301 ctgagcaaac cctaagtgat tcagcaaact acggacaagc gattctgaaa actctgtttg
     6361 tctcatgaca aaacgaatga tggattcttc agatgtcatt tgataaccct tttgctgata
     6421 tacttgaaag cttactttcg gagagagaag gattccttct ccttgtttgc ggatatgttc
     6481 taataaggtt gtcttacctg aaccattttc accgacaatc gcgatttttt tacctaaaga
     6541 aaactgaaaa tcaccattta ccagtaatgt tctcccactt ctttccaatt ggacattttg
     6601 tcccatgatg ggatagcggc tgtggagttc aagagatttt ggtactggaa aacggatttg
     6661 tttcatctgc tgcggcttgg ttgtttctcc tattttttgg agtcttctct ctaatgtttt
     6721 cgcattcttt tggatggctt tttgtacact gtctttttgt ttagaggaag acaaccgatc
     6781 cggtctgatt tgttgctttt tctttttact ggacactttt tccaactttt ccgcttgttt
     6841 tttcttttct tggatcgatt tttccaatcg ttttttctct ttcatgatcg actctgcttc
     6901 tcgtagctga gtctttttct ccaattcctt ttgagtgaga taggcactat aattccccga
     6961 aaactctcgg atttctccgt cttttacttc ccagattttc gatgctagct catctagaaa
     7021 atagcgatca tgactaacaa aaaccagcgt accataataa taacgaagct cttcaatcag
     7081 tcgatcaata ctttttctat ctagatgggt tgttggctcg tctagaagca tcccttgttc
     7141 ataagaagaa agaagacgta tcaactcgat ctttcgttct tcccctccgc tccatttccg
     7201 ctctgaagtt tcttccagtc ttaactggaa atgactggct aattccaaat ttaggtcctt
     7261 tgcttcagcg agataggtta attgaggcag gtagttgaag gtgatctctg tttggatttt
     7321 cccatgatcg ggaaaaagtt caccggctat tagtttgagc aaagtcgatt taccgacacc
     7381 attttctcct atgatcccta tacgatcttg ctgatagaca cgaagagaat caatagatag
     7441 ttctagctgg ttgccaaagc tgacttgtag atttgttata tttactgcta aattttccat
     7501 atgttttaca ctcctatttc atgtaaaaca acaattatcg atactaaaaa agagcagaaa
     7561 aatctgtttg caaaaaaact gcatcacatc ttttcctact ctgaacgaaa taactatgac
     7621 taaatcacca aatctgtcat agctttcacc tattctactg tcgttcgaaa aaatggacat
     7681 actccatcca tgaaattgtt gtttatacat gtcttttgaa tttatttagt tgttattcaa
     7741 aagttcgaaa cgtaatttca tcgatgcagt catttttccg acctcctttt ttattaggtt
     7801 accacacacg attcaaaaaa agcaatagct actgaatagt aactgaaaac cttttattcg
     7861 aacgtagtga tcttttctgg tgctaaacga acagactcgt aaccttcttc taccgctttt
     7921 cctattgata aaataataac tggaacataa cggtctttat ccaaaccaaa tgcctctgcc
     7981 aactgatctg cttcgactcc accaattgga tttgtttcat agccatgatc acgcgcaact
     8041 aacatgaatt gcatagccgc taagctagaa tcgactttga ctacatcgtt catttcttct
     8101 cttgaaaaac tcttgtaata aggaatgatc gcagctaatt gttgatctct gacttctttt
     8161 ggcatcttcc ctgattcgta agcttggtta tagatttctt cgccatattc gtaacattgc
     8221 atatcgccaa aaatcatgac cattgcagaa gaagtatcat tttgtctcgt attgaaacgg
     8281 atcaaaggac gcaagatttc ttttgcttcc tcgctttcag cgaccacaaa gcgccatggt
     8341 tgcatattga cagaagaagg tgcagtcgtc gcttctttga tcatttccag catttcttcg
     8401 tgtgggattt tgtatgtttc atcatatacg cgaacggatc ttctaccagt cataattgtt
     8461 gaaaaatcat ttttttgttc cattattatt aacctctttc gtttctgttg ttatattgca
     8521 aagttgggta ttcaatttat ctaaaagtgt tagaaattgt ttcatttcta catcgctgaa
     8581 agccggggat agcacggaac ctgtatcttt atggtccatt tcacaatgct cgattttctt
     8641 ctgggctttt tctgttagcg ctacatacac ttcccggttg ttctgaggat ttctctgacg
     8701 cgaaacatag ccatttgctt ccaatacctt cagatgacga gtaactgctc cttgatcaat
     8761 ctgcaacttt tcttgcaaac tgctttgtag caatggattt tcttctttca gtctcatcat
     8821 gatctcgtat ctagtaagac ttataccgat attttcttca aagatctgga cgattttttg
     8881 atcggctaat ttgatttgat ataaaaggtg actaatctct tctaaagaca taatttcctc
     8941 ctttctaata attgactcgt caacgattga cttgtcaata atagaataaa aaaagaaaaa
     9001 agtcaaagaa tcagctgtgt aataaaaaaa acgctctcaa tagaaaagta tagagaaaag
     9061 aaattttttg tagaatgaac ggaaaaaatg ataaagaaag cacaacgcta aaaccaagat
     9121 tattgattct tatcaaacta tagaagatag ctcttctgca gtagaaaatt ttacaccgcc
     9181 aaaaatttcc gaaatcgcct tttgcaagaa tcccgtcgaa tattagaaat tggatcagta
     9241 tgcttaaaca gtaataaaaa agttatgaca agatgttgtc acaacctttt ttgagtaaac
     9301 ggtgttcaaa aacttgcatc tgcggtaata agttcaacca aacaaaaaac atgaaaatct
     9361 gtttttgttt ggctgttctt actacttgat gcagggcagc tttttcacta cctcttttta
     9421 ataaccataa aatcctattc cttcatatct ccagcccatc ggtgttagcc aatctctttc
     9481 cttagcactc aaggtatagt gatgggtacc agttttttca tttggattaa atagtcgata
     9541 aattggcttg gaaccaccag aataaaaact tagaccttca taacgccaac cgatttttgt
     9601 taaagagttg atctcagatt gtgccattgt gtaatgatgg tctccactgt aaggattgta
     9661 taaacggtag acaggttgtc cgctgtttgg tgcttgccaa gcaatccctt catattccca
     9721 gcctacagtt ggcagataat ttttttctcc ggcattcaat gtatataaat gttctcctgt
     9781 atgacggtta tacagacgat acatcggaga agttgaagtt ggtgctgtat catactgtgt
     9841 cagattatag gtttcgatta cattgttcaa tgtagaacca taattaggcg cagtggcata
     9901 acgacctgtt agccaagccg tagcatcttt gtaagagttc gtattgcttt tccatgcacc
     9961 ggaatagtag taaacgcctg gctgaaaaga agtcgtcttc aataccgtta cgttatcttg
    10021 caatgattct ttgtacgaag gatattttct aaaagcggca ttcaccgtaa tccattgccc
    10081 attcacatat tccgaagtag gcatcgtaac agattggcca ttatagcttc ctttaatccc
    10141 aaatagattg taattagggg cagaagccaa agtactgttc ccccagccac tttcaacgat
    10201 ggcttgagca atcatgactg atgcatataa gtcattggca cttgccaaac tttgtgcagt
    10261 tgaggcaata ctatcaatga acgcttgttg agaattagca gatgagcgag cataaaaagc
    10321 atagccagta tagttttcga attcagacaa atctgcttga tgggtatgtg tcaatgtttg
    10381 cccatctgtc aattggttcg tgatttcttc tgcattctct ggattgttct gagcttctgc
    10441 tgatgtactg tcttcggttt gtgtttgttc tgttgtttca gttgttggtt cttcggttga
    10501 aattgtattt tctgagacag tagctgactg caaagtactc tctgtatcgt tttcaattcc
    10561 tgtttctgaa gaactcgatg tctgagttgc gacagtttct gtcgattctt cagctagcac
    10621 tgttgtgttg gcaactgcta gatttcctaa aagaataacg ctaaataata aattctttgc
    10681 tttcatcttt tttctccttt gaattatgaa acttttccta aataacagtg taactaaaaa
    10741 agtaaaagca agtcaatgtc catatttaaa taacatttgt ttctttttga taaatttgct
    10801 ttttctacat aaaaagacgt aaatgaagaa tattcttctc cattcacgcc ttaaattgat
    10861 ggtcgtttga ataactattt aacaagtaat tctctttgga tattatccgt tatggattat
    10921 acttcctgtg tcgtcggacg gataatcatg ttactgacag acatccggtc tggcgtttct
    10981 atcgcaaatg ctacagcaga agctatatct tcggaggtca atccccattc tttttgcgct
    11041 tcatgaagtt caagagcagc ctttttgtcg ctgatggttt gatataattc agtttgaaca
    11101 gctcctggag agatgatcgt agatttgatg ttattttgcc gttgctcttg acgtaatcct
    11161 tccatgattg cacggacagc aaattttgtt ccgcaataaa cggcggaatc aggataaaca
    11221 acatgtcccg ccacagaatc agttgaaatg atatgcccag atttttgttt ttccatgatt
    11281 ggaagtacgg cggaaattcc atttaacaca cccatgatgt tgatatcaag catattttgc
    11341 cattcatcac ggtgaccttc aactaatgga gcggttggca tgattcctgc attattgtac
    11401 aatacatcga ttcgaccgaa cttttccatc gctaaatcga taactgcttg gacttgtgca
    11461 aaatctctta catctgctgt ttgaatatat agctcagctt ctggtaaaga ttcttttatt
    11521 gcttttaggc gatcttctcg gcgtgcagct ataactagtt tagccccttt ttctgctaat
    11581 agcttcgttg ttgcttcacc gattccgctt gaagcgccca tgatgacaat cactttttct
    11641 gataaatcat tcattctatt ctcctcctgt tttgaaaaat ctcttgctta tactcactat
    11701 ctcttatttc atcttactgt tcaaataatc cgttcgacag gtttgacgat tttggcaggg
    11761 attcctgcaa cgatggtatt gtctgggaca tctttcgtaa cagttgcatt cgctgcaaca
    11821 atggcattct cgccaatcgt tacgcctggc agaatagttg ctcctgctcc gatccaagca
    11881 tttttcttga tgtggattgg ctttactaac aagcctcttc gttcttttgg atcggttaga
    11941 tggttcaccg tgatgaggtt gacacgagga ccaatcaata ctgaatcttc taaacagatg
    12001 ccacctaagt caacgaacat cacttgacga ttgataaaga catttttccc tatactaata
    12061 tgtttgccga aatctgtata aaaaggcagc agaacagtca ccgtatcatc tactttgtca
    12121 ctaatgatat tttctagccg tttgcggata tctgctggtt catggtaccc agtattcagc
    12181 gctgctaaag gctcttcgtt ttcagcttgg atctgatgga tcacttcaaa gagcggatcc
    12241 gttactcgaa tctctttatt gacgatttgt ttttcgatga ggcttgtcat tttgctccct
    12301 ccttttatcc ttactttata acggacggct tatcatgtct aatacttata aaacatactt
    12361 aactattcct tttaactata cttagtggta tgctttttta aaaacaggag ggaaaaaatg
    12421 gatattcgta tactgacgta ttttttagca gtagctagag aaaaaaatat cagccgagca
    12481 gcaaaatctc tgcatatcac gcaacctact ctctcaaaac aactgaaaga tttagaagaa
    12541 gaacttggtg tgacactttt cactcggggc tcccgagaga tacagttgac ggattctggt
    12601 cgatatcttt attcaaaagg aaaagaaatc ttgtcgttgg tagaaaaaac ggcgaacaat
    12661 ttaacaaatg acgcaatcat ctctggagaa atctacattg gcggaggcga aactaaagca
    12721 atctctttca tttctgatag ccttcattcg ttgatcaagg cgcatcctga tatccagttt
    12781 catttatata gcgggaatgc agatgatatc atagacaaac tggatagcgg attacttgat
    12841 tttggactcg taatcgaacc gacaaacaaa caaaaatacc agtcatttcg actgccagcc
    12901 caagatcgtt ggggactttt gatacatcga aatcatcctt tagcaaagca aaccgtcatc
    12961 catccgcagg aactgaaaac tgttcctttg atcatttccc ggcaaacgtc agtggacagt
    13021 caactagctg aatggctagg tttcagcata gatcagttat cgatcgtcgg aacatataac
    13081 ttattgtaca atgcttcttt gatggtcgat aacgggactt ttggtgcatt agctctagat
    13141 gggatcatca atacttatgg gacggaaaaa atattcatcc cactcgatcc gccattacaa
    13201 gcttcactga atctcatttg gaaaaaagac cagcctcttt ctcctgctgc tcgtaaattt
    13261 ttagatgtcc taacggagaa atacagttaa gtagagtttt tttccttcgc tttcagcttt
    13321 ttaacaacga ataagataag caaaagatcc aacgattaaa taacataagt ttcttaattt
    13381 atttcttcct tttatttctg ataattccag taaattacta taattataaa aaaagaattg
    13441 acaaaacata actgtctata taaaattgat tacgttaaca ataattcgtt tcatgtgact
    13501 agatcatact aggcatgaaa aatctctgag gaacatggtt tccctaggag gtttttcgtg
    13561 tctatttttg tttggccgca atcaactggt ctagcaaacg tgaaaaccaa atcttcaaaa
    13621 agggtgcgcg catgaaaatc aaaaagatct ttaatcaaaa tgcagtattg gtagatgacg
    13681 gtggacagga aaaagtagct attggaaaag ggattggatt tgacagaaaa agaaatgatt
    13741 tgatttttga tcgtgatgtc gaacggatat ttgtcatgga accagaaggt caaatcaagt
    13801 tgcaaaattt acttaatcag attgatgaac gctttttatt tgcagcagaa acgatcattg
    13861 atcatgcgga aactgttttg atggaaaagt tgaatgaaca tgtattgatc gctttgaccg
    13921 accacattgc tttttctgcg gagaacatta ataacggtat cgtcatccgc aacaaacttt
    13981 taagagaaat cgaagtgctt tacagtgatg aattcagtat tgctcaatgg gcagtagagt
    14041 atctgacaaa agagcttggg attccatata cttatgacga agcaggatat atcgcaatcc
    14101 atattcacag cggacgaagc ggtcggaaca ataaccatcg cagtatccgt gaagtgacga
    14161 ttgtatctga catcatccat ttagtggaat cagaattgga aacagatatc cattcagaac
    14221 cattttcact gaattattca agactggtga atcatttacg actgcttcta caacgaaccc
    14281 atgcgcaaca atatgctgtt ttagacacgg aaatcgtaga aatggtcaaa cgaaaatacc
    14341 cagaaagcta taagatttct aaaaaaatcc gtgtgttgct gaccaaagaa taccagctcg
    14401 cgatcacgaa agaagaactg ggttacttgg ccatccatat cgagcgttta agaagcgcaa
    14461 tcgtacaaac aaatgttaac aatcatgagg aggaaaaaaa ttgaaagcat atctacaacg
    14521 aatgggacgt tcccttcaac ttccagttgc ggtcttacct gctgctgctt tactagtagg
    14581 gatcggaaac tggtgggcat cttatagtaa cgacattgtc gctcattttt tacaagctgg
    14641 cggtaacgca gttttaggtc aattaccttt gctgtttgcc gttgggttag cactagggat
    14701 gtcagtggac aaatcaggtg ctgctgcctt ggcaggtttg gtcgcatttg aagttccagt
    14761 aaatgtttta aaaactgatt cagtagctac tttattgaat atcaaaccag aatcagttga
    14821 tccatctttt gctcagatca gtaacgtatt tattggtatt attgccggat tgattgcggc
    14881 agctctttat aatcgtttcc acgaagcaaa attaccgatg gctttatctt tctttagcgg
    14941 caagcgtcta gtgccaatct tggctgcctt tgtcatgttg ctgatcagtg cagtgctact
    15001 gctcgtatgg cctccggttt actctgcttt agtttctttt gctaaattca ttttgagttt
    15061 aggctggggt ggtgcaggtc tttatggctt cttcaaccgt ttactgatcc ctacaggatt
    15121 gcatcaagca atgaactccg tgttctggtt tgacgtagca ggaatcaatg atattggtaa
    15181 atttttggct tctgaaggaa caaaaggcgt aacaggaatg tatcaagctg gatttttccc
    15241 aatcatgatg ttcgggcttc cagcaggagc atatgctatt tacagaaatg cacgtccaga
    15301 aaacaaagca aaaacagctt ccttgatgct agcagcagct tttgcttcat tctttactgg
    15361 tgtgacagaa ccacttgaat tttcatttat gttcgttgct tggccattat atgtcttgca
    15421 tgcaattttc actgggattt ctttagcagt gagtgcattc ttccattgga cagcaggatt
    15481 tgcctttagt gccggatttg tcgattactt cctatctttg aaaaatccga ttgcgaatca
    15541 gccattgatg ttgatcgtcc aaggattagt aacagcagtg atttactact ttggctttaa
    15601 ctttgctatc aaaaaattcc atctgatgac tcctggccgc gaggaagcag atctttcaga
    15661 tgacgatact gcaacgacta attcagacaa taaatatgcg gcacaagcaa gcaaaatcta
    15721 cgctgcatta ggcggagccg acaatgtaac ttcgatcgat aactgtacta cacgccttcg
    15781 tttgcaagtc aaagatacag gcctgatcga tcaaaataaa atcaaagcca ctggcgtacc
    15841 tggtatgaag atcatcgacg gaaaaaatgc gcaagtcatc gtaggtacag aagtacaatt
    15901 cgttgcagat gagatggcaa aactacatgg tggtgctgca gcacgacctg cacaaacaaa
    15961 caccgtggtt aaaacagaaa catttgccgg tgaaacgatc gaacaagata tttacgctat
    16021 cgcaaatggg aaactgattc caatcactga agtttcagat gatgtattcg cggaaaaaat
    16081 gatgggtgac ggctatgctg tattaccaga aaatggagaa atcttctctc caatcgctgg
    16141 tacgatcaca aacattttcc caacgaaaca tgctgtcgga atccaaacag atgctggtat
    16201 cgaagtcttg cttcatatgg gcatcaacac tgttgactta aaaggcgaac cattcacttt
    16261 atatgtagaa gaaggtcaaa aagtcgcaag aggtcaattg attgctttag ttgatcttgc
    16321 cgctattcaa tctgcaggca aaaacacgga tatggtcgtt gtattcacaa atggcgacaa
    16381 agtccaaagc ttagaaatcg aacccgcacg tgatgtaaaa gcaaatgata aaatcggctc
    16441 tgtttccaac aaagcctgag ccatcgtctt ccccagactt ttttatcgat aaacaaacag
    16501 gagctgagac aaaaatcttg tctcagctcc tttttccgaa taaaaacggc gttctcctgc
    16561 caactccgcg gtaataagtc cagctaaacg aaacatatga agagctattt tttatttgac
    16621 tcttcttatt acttgatgca gaacagcttt ttcacaaaat ttttcttcat actcaaaact
    16681 aatcggcttt ttcacaacct ctttatacat tattcctgat ccaatatttc ttttaatgct
    16741 gcttcaagag aagttaatgg ttttcccaat actttttcta aatcatcaga ggaaatagct
    16801 aactgatcct ttttaatatc atgttggatc gctaaaaaca tgtcagctgc ttcttgaggg
    16861 aatccggctt cttttagatt ttcgacaaac gctgcatcac ttgcttcaat aatttctaac
    16921 tctttacctg tcgcacgctc taatgccttg gctaattctt catagtcagt tagattgccg
    16981 gataattcta agatttctgg agagtcactt tctactagta cttttgctgc agcttctgca
    17041 tattcacgtt tcaatgccca acctgttttt ccatttcctg cagcataaac gaattgacca
    17101 gtttttaaag cctgcccaat gataggtaat tcattctcta cataccaatt attccgtaaa
    17161 aatgtatggg aaatacctga atccttaatc attttttcag tgaattggtg atctggcgct
    17221 aatacactga tcgagtgatc ggcatctgca aaacttgtat aagcgatata agatacccca
    17281 gctgcttgtg ctgccttcac tacattctta tgttcggctt gacgatttcc tggaacgcca
    17341 gagacaaaaa gcaatcgatc tattcctttc aacgcttctt tcattgagtc taaatcatca
    17401 taatcaccaa tacgtatatt aaatccagct tctttcagtg cttctccttt ttcttcacta
    17461 cgtactagta catagatttc attttgtgga accatctttt ttaagaattc cagcgcataa
    17521 ccaccaaaac ctccagttgc tcctgttact aaataatgca tatttgccac tccctattct
    17581 ttttatttgt taagatttac agctgtacat ttataaatta cacctttatc ataaagagtg
    17641 tggtaagata agtcaagcaa aaaaaatgaa aggatgacaa ctgatgaagt attctctgca
    17701 atttagtgat gcaatccatg tacttgccta tattgaaatg tttcaagata cccgatcact
    17761 ttctagtgag atgattgcca gtagtatcga aacaaatgca gcaaatgtac gtaaaatcat
    17821 gagtcagctc aaaaaatccg gtttgatctt tacaaaaacc ggaaaaccgc agccttccct
    17881 tgccaaaagt ccagatcaga tttctttact agatgtctat cgcagcatcg aaggtaatac
    17941 acagcttatc caagtcgatc caaaaacaaa tccaaattgc gtcgttggtg cgaatatcca
    18001 agaagcttta gaagaaagct acgctcggct gcagaaaaag gcagaagaag aaatggctaa
    18061 gatcacactt gatagtctga tacataaaat agccgttttg gaaaaagaaa aaagaccaga
    18121 aaacacaggc ctcgtagaga gatttttata attctctcta ctgtgcctgc atttttctga
    18181 tcggaatcgt ctacataaat tcttttattc tccgggggac aaaagccttg tcatgcccct
    18241 ttttcctctc taatgctcag gtcaaagcgc tgaagtcatg acgtcttgat aaacggtgtt
    18301 caagtagctg accctcggca ttagttctga aaaatgcaaa atatggaaag ctatttccca
    18361 tttttcctct ctaatgctca ggtcaaagcg ctactttcac gacctctata ttatcatggt
    18421 ttattgacta ccggtatcca gatttctccc atatatttcc cgttggtaac tcccatttcg
    18481 actacagcat ttggaccccc aacataggcg taatcttcta cttctcttaa aacatgccca
    18541 aaggccgtat tcgtcaaatc atttcttaat tcttcaggcg attctgctaa agcgcttaca
    18601 acaagatacg ttccttttgg gaatgggatg attcgcgtag tgtttggaac atcctgactc
    18661 gtttgaacac cgacatagta catcattttc ccgttatagg gttcgttgac tgtaaagaaa
    18721 taatgatttt cagcagcttg tttcaatgca tctattgttc cattaccgat aactttttgc
    18781 tcaaatgctt gtttctctgc agccaaaccg acaaaatccg tattgctact cttcaattcc
    18841 acaccaatac ccgtcaccgt aaaatctggt ttttcttcga tcctatactt tgccatttct
    18901 cccacccttt ctattatatt aagttcatct tacataaaat taaagggaaa tgacacgatt
    18961 acgctctttt ttctagggat atttttattt tttaactatt tttttgcttt cactgcaatc
    19021 caaatctcac tgtaaacatt actgaaatcc tctccccatt ttgtaaaaga gatctcggga
    19081 gcttcgacta acccataatc tgaagaagga agccattctg catagatttt cccccaagta
    19141 tcttgtaaag tttggggaaa tggcccttta ttaggaaaaa tggcccaagt gtgttcttct
    19201 atagcaagca tttctaaatc agcgtacgga ttttcttttg tcgtagcaaa gccaatcatg
    19261 tgcatcaaac tgcccttttc ttccaagcgg tctccatcaa atccataaga aacgttgatt
    19321 acttgatttg gatataaatc tcctaactta tgcatctctt ccctttgagt ctccgtgatc
    19381 gtctgcgcta acttttgtat ttcttgattg actccttcaa atttgacagg aacttttttc
    19441 gccacacctg ccacataaaa ctgttctttc ttttcgatac gaaattccat cgattttcct
    19501 cctctgacat caataaaaaa tgtcaagcgt ggaaaagatt tttgtatgcc gtatctgctg
    19561 atttctgaag gcagatatcc tgaccaatca cgaaaagctc ttgaaaaacc ttcgactgtt
    19621 tcatatccat atctaaacgc cgtttctgtc actcttgatc catctagaag atcgcgatta
    19681 gccaaagcca atctacggtt tttgatatag tccattagcg acatccctgc aataaacgta
    19741 aagatgcgtt ttaattgata ttcagagatt cctgtatttt cggctattat tttataggaa
    19801 agtccttctg tcaaatgttc ttcgatgtaa tcgatcaatt ggttcagatc tttaagcata
    19861 tttatcttcc tccttgattg cctttttatc atattatcaa agaaagtcaa ttacttgatg
    19921 aatcaggaac caatttagtc agatgtagaa aatgttgtat ggatctaaag aaaattctca
    19981 agcagcgttt cgtaacggat aattggtatt atctgcctat ctatgtttta cctttagaaa
    20041 aataaatttt ggggaagaca gattctaagt aaacaaagcg gtaaaaatat cttttattcc
    20101 cttagttaat ccgcttacta cctactgtac aaagcaaatt gttgttcaaa ctgctgatca
    20161 gaacgctgct tggatttttc tttg
//
LOCUS       DACBYO010000048        20033 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.048, whole genome shotgun sequence.
ACCESSION   DACBYO010000048 DACBYO010000000
VERSION     DACBYO010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20033
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.048"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..299
                     /locus_tag="IVD26_001696"
     CDS             <1..299
                     /locus_tag="IVD26_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079659.1"
                     /translation="DYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKPV
                     RTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(396..830)
                     /locus_tag="IVD26_001697"
     CDS             complement(396..830)
                     /locus_tag="IVD26_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6079660.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1062..1772)
                     /locus_tag="IVD26_001698"
     CDS             complement(1062..1772)
                     /locus_tag="IVD26_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP6079661.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1762..2622)
                     /locus_tag="IVD26_001699"
     CDS             complement(1762..2622)
                     /locus_tag="IVD26_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAP6079662.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2627..3265)
                     /locus_tag="IVD26_001700"
     CDS             complement(2627..3265)
                     /locus_tag="IVD26_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAP6079663.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3280..3579)
                     /locus_tag="IVD26_001701"
     CDS             complement(3280..3579)
                     /locus_tag="IVD26_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6079664.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(3622..5106)
                     /locus_tag="IVD26_001702"
     CDS             complement(3622..5106)
                     /locus_tag="IVD26_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAP6079665.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5126..5587)
                     /locus_tag="IVD26_001703"
     CDS             complement(5126..5587)
                     /locus_tag="IVD26_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6079666.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5605..6672)
                     /gene="ulaG"
                     /locus_tag="IVD26_001704"
     CDS             complement(5605..6672)
                     /gene="ulaG"
                     /locus_tag="IVD26_001704"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAP6079667.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            6890..7660
                     /locus_tag="IVD26_001705"
     CDS             6890..7660
                     /locus_tag="IVD26_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP6079668.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(7933..8760)
                     /locus_tag="IVD26_001706"
     CDS             complement(7933..8760)
                     /locus_tag="IVD26_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6079669.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9328..10563
                     /locus_tag="IVD26_001707"
     CDS             9328..10563
                     /locus_tag="IVD26_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAP6079670.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(11562..11822)
                     /locus_tag="IVD26_001708"
     CDS             complement(11562..11822)
                     /locus_tag="IVD26_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP6079671.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(11849..13150)
                     /locus_tag="IVD26_001709"
     CDS             complement(11849..13150)
                     /locus_tag="IVD26_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6079672.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(13442..13900)
                     /locus_tag="IVD26_001710"
     CDS             complement(13442..13900)
                     /locus_tag="IVD26_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP6079673.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(13913..15238)
                     /locus_tag="IVD26_001711"
     CDS             complement(13913..15238)
                     /locus_tag="IVD26_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAP6079674.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREIMP
                     EIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVVEH
                     TDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLNDDR
                     RRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAVEK
                     LLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15255..16667)
                     /locus_tag="IVD26_001712"
     CDS             complement(15255..16667)
                     /locus_tag="IVD26_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6079675.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            complement(16684..17448)
                     /locus_tag="IVD26_001713"
     CDS             complement(16684..17448)
                     /locus_tag="IVD26_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAP6079676.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(17552..18427)
                     /locus_tag="IVD26_001714"
     CDS             complement(17552..18427)
                     /locus_tag="IVD26_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6079677.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(18682..18766)
                     /locus_tag="IVD26_001715"
     tRNA            complement(18682..18766)
                     /locus_tag="IVD26_001715"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18730..18732),aa:Leu,seq:caa)
     gene            complement(18784..18855)
                     /locus_tag="IVD26_001716"
     tRNA            complement(18784..18855)
                     /locus_tag="IVD26_001716"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18821..18823),aa:Gln,seq:ttg)
     gene            complement(18865..18937)
                     /locus_tag="IVD26_001717"
     tRNA            complement(18865..18937)
                     /locus_tag="IVD26_001717"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18902..18904),aa:His,seq:gtg)
     gene            complement(18999..19083)
                     /locus_tag="IVD26_001718"
     tRNA            complement(18999..19083)
                     /locus_tag="IVD26_001718"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19047..19049),aa:Leu,seq:caa)
     gene            complement(19104..19174)
                     /locus_tag="IVD26_001719"
     tRNA            complement(19104..19174)
                     /locus_tag="IVD26_001719"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19140..19142),aa:Cys,seq:gca)
     gene            complement(19220..19291)
                     /locus_tag="IVD26_001720"
     tRNA            complement(19220..19291)
                     /locus_tag="IVD26_001720"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19257..19259),aa:Gln,seq:ttg)
     gene            complement(19303..19375)
                     /locus_tag="IVD26_001721"
     tRNA            complement(19303..19375)
                     /locus_tag="IVD26_001721"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19340..19342),aa:His,seq:gtg)
     gene            complement(19378..19451)
                     /locus_tag="IVD26_001722"
     tRNA            complement(19378..19451)
                     /locus_tag="IVD26_001722"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19417..19419),aa:Trp,seq:cca)
     gene            complement(19458..19538)
                     /locus_tag="IVD26_001723"
     tRNA            complement(19458..19538)
                     /locus_tag="IVD26_001723"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19502..19504),aa:Tyr,seq:gta)
     gene            complement(19540..19615)
                     /locus_tag="IVD26_001724"
     tRNA            complement(19540..19615)
                     /locus_tag="IVD26_001724"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19580..19582),aa:Phe,seq:gaa)
     gene            complement(19651..19723)
                     /locus_tag="IVD26_001725"
     tRNA            complement(19651..19723)
                     /locus_tag="IVD26_001725"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19688..19690),aa:Asp,seq:gtc)
     gene            complement(19733..19805)
                     /locus_tag="IVD26_001726"
     tRNA            complement(19733..19805)
                     /locus_tag="IVD26_001726"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19770..19772),aa:Val,seq:tac)
     gene            complement(19821..19892)
                     /locus_tag="IVD26_001727"
     tRNA            complement(19821..19892)
                     /locus_tag="IVD26_001727"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19857..19859),aa:Glu,seq:ttc)
     gene            complement(19907..19996)
                     /locus_tag="IVD26_001728"
     tRNA            complement(19907..19996)
                     /locus_tag="IVD26_001728"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19960..19962),aa:Ser,seq:gga)
BASE COUNT         6262 a         4244 c         3177 g         6350 t
ORIGIN      
        1 tggattatac tgttgaattt gacagtgaac tacttaagca atttccacaa gaagaacatt
       61 tcatgtataa agaagcaatt tcccacaaag tgacagagta tttggagcat aatttttttc
      121 gtataaagcc agtgcgtact cgttcggcaa aaggaatata cgagatgaaa gtcaaaatta
      181 ataaaaaaaa ttatcgcata gcatttgctt taaaaaaaaa tcatgtgttc attttttata
      241 ttagttcgaa tttgcaaaaa attgtatttg ataaagaggt gagtaaaaaa ataaaatagc
      301 tgagcattgg aggatagatt gagtgatact aagtctatcc tcttgttttt ctaaagaact
      361 aagctagaat tttttctttt gtacgttatt atatgttatt tgtcattacc aaaaagcacc
      421 ttttttcttc tagtatctat gacataagaa ataccaccca tttcctttac ttgaacaaat
      481 cctactgatt cataaaattt ttttgttttc tcagtatcat ctgtcaataa ttcgatttgg
      541 actggtccat aactagtgat cttctccaaa gcttcattca aaagcacttt gcctattcct
      601 tggcgctgat acctcggatg aatgaggata tcttgaataa atgcgatcgt cgcaaaatca
      661 gtgatccaac gaacgattcc gataatcttc ccttccccat tacgctttat cagagattca
      721 gattgttcaa atgctctagc taaccttgca gtgtcttttg tgtaattcgt ccaaccaacg
      781 ctcttatata attcagaaat ctcatcgatc ataagggaat caatattcat ttttttcttc
      841 ctttcttata caattctccc tctaataata cagttctttg actatttaat ctatcacata
      901 taactctcct gtaaagattc tctcgattcc ttaaaattcc tctttccttt tagaatgcat
      961 actttttgat aaataaaaag gttgtgataa attttcttca caacctctgt ttctctctat
     1021 caagtgttat cttttaattt tctaccctta ccctagcatc tctattgccc gtagtatgca
     1081 tactttccat gtttgcgaaa ataatgttta tctagtaaat attgcgggat ttcacatata
     1141 ttggggttga tcagctcgtt ttctttggcc atcagacaaa tttcatctaa gatcaaactg
     1201 ttttctactg ctttcatagg tgaatccccc catgtgaacg gtccatgtcc atagacaagt
     1261 actccaggga cttcgtttgg atctaatttt ctttccttaa acgtctcgac aatcacattc
     1321 cctgtatgaa cttcgtaagc ttctcttact tcttctttcg ttaattggcg tgtacaagga
     1381 accttaccat aaaaagcatc agcatgagtc gtgccataag ctggcaaatc gcgtcctgct
     1441 tgcgcccaca tgacggagtg cgtggaatga gtatgagtaa tagcagttat atcttcaaaa
     1501 gtttgataca aaacaacatg tgtggggaga tctgaagatg gttttaagct atcttcttct
     1561 attatatttc ccgacaaatc tgttaccacc atttgatctg cttgcatgca ttcatatctg
     1621 acaccgcttg gcttaatgac gatgactcct agctcacggt ccacttcact cacattgccc
     1681 caagtcaatt tgactaatcc gtatcgcggc aatgccagat ttgcttcaag gacacgttgc
     1741 ttcattgctg caattttttc ttcacaagac atcatagcca gcctccttca atttagaact
     1801 taagtagtct tttgcctgct ggatttctct tcgaaagtct tggctttttt cactccacat
     1861 ttcaatcaga aatgttccat cataatctag acgtttcaaa tgtcttaata atccaagaaa
     1921 atcaacacaa ccgctaccaa aaggaacatc acgaaactgg cctgaatatt cttttgttac
     1981 agggtaagta tcttttaagt ggatagcagt gatataatcg atccctttct caagttctcg
     2041 agccggatta ttttccggcc atgcggacaa attgcctagg tctggatata cttgtagaaa
     2101 aggtgaatga atctgttctt tgatttctaa aaattttgaa atggagttca taaatggatc
     2161 atccatgatt tccacggaaa gaatgatgcc atatttagaa gcttccttta cgctttcttt
     2221 tattccttcg ataaagtctt ctctggaatt cattgatttc tcttcataat aaacatcgta
     2281 tccagctatt tggattactt tgacgcttag attatgcgcc aaatggattg cttttttcat
     2341 tagttgtttc gctgcttttt tcttttctgg atcagcagaa ccaaacggaa atcgccgatg
     2401 cgcacttaaa caaatcgaat ggatacgtac accggagctg aacatctctt ctctcagctc
     2461 agctatcttt tcttcagacc aatctaatcg tgctaaccgc tcatccgtct catcaatcga
     2521 catctcgata aaatcgaagt ccatttcttt tacaagggaa aaacgttctt tccatgaaat
     2581 atctttgggt aacgcttttt cataaatccc aatttgagcc atttccttac ccccagatac
     2641 gaatgatctc atctttgaag ttttgtgcgg ccttcatcgg atcatttgct gctgtaatac
     2701 cacgaccagt gataaaggta tacacatcga tcccttcaaa taagtgtaat gtgtgtggat
     2761 ttaatccacc agttacagaa acattaaagc ctagttcaat cagttttttg atcttcgata
     2821 aatctttttc accccaagtt tcaccagata acagcgcatc acggctttga tggtagatta
     2881 cctgccggat accgatgtta tgccaatcca tggcttgttc aaaagtccaa ttgccgtaga
     2941 gttctacttg caattcacct atttcttttt gtgctgcctc catagttgga atcgttgcac
     3001 aacaaatgac tgtcatccag tctgctcctg cttttgcaac attactcgcc actgttcctc
     3061 cagcgtctgc acatttcgta tcagcgacta gttttttatc tgggaacata ctgcgaatac
     3121 agcgaatcgc tttttgtcct tcctgtaagc aaagaattgt gcccacttca ataatatcta
     3181 ctacatcacc aactttcata acatctccta atgcatgttc taagtcattg tgatctaacg
     3241 caatttgcaa attcggcctg ctcatcttag ttccttcctt tacttgtttt tttggtacca
     3301 ctttgtttca gcaaattttt cactgatttc tttgactgac atcacatttt tgataccgat
     3361 aactgtaact ccttttttct ctgcctgagt aaacatattc aaaaaattga ctggcgtaaa
     3421 aactacatcg tattggccag ctgaactttt tccctctgaa atggcacaat gatggatttt
     3481 ggtaattggt acgtttagtt ctttcattgc tttttccaca cttctcatca tcatcaagct
     3541 tgttcctgat ccatttgcac acgatactaa aattctcatc ttaatccctc cattatgagt
     3601 gttgtctaat cagattttct tttatactct ctgcttttct gcatatgtgt catagtcttc
     3661 tacaatcaaa aaataaccat caggattttt ccgatattgt aactgcggaa tagccaataa
     3721 accaatgaca actacggcaa ttccagcata acctaggact ttcatgatta ctgtaaacaa
     3781 tggccaagct gttgcccagt cgaacatccc gatataacca ccgtatgttg acatcccaat
     3841 ccatgtagcg aataatgctg aaccgcctac ttgtatgatt cctgaaagaa acgggaacag
     3901 gcaagcggct ttgaatccac ctcggttatt ggcataaact gctataacgg cattatcaaa
     3961 gaacaacgga atgaaaccgg ctatgacgat cgttggtgat ttcaataaaa tcagtaaacc
     4021 aatcatcaaa aactgtccca aagcaccaaa caagaaccca atcgttaccg catttggcga
     4081 accaaagcca aaagtagcag ctacgtcaat tcctggaaca gctcctggta aaatcgtgtt
     4141 tgagattcct tggaaagatt gagttagttc atcgacgaat gtccgaacac ctaattgcaa
     4201 gatcgccaga tataccgcaa aatttaaaga agtcgtcata atgtagaata agaaactctg
     4261 cccttcttgc atgaattgcg cttgaatcaa ataatctttg cctagtacaa tcagaatgat
     4321 cccaaagaaa aatagcatga gtaacgaagt agcaaccata ttctcattga aaatcgacaa
     4381 gaatcctggt aatttgatat cttcaatttt tttgtcttgc ttgattgatc tatttttctt
     4441 ttcatcccgc tttttcatcc actcagctaa ttttgcaaat ataaagattc cgaacatttg
     4501 ctgatgtgcc actgcaaatc cggcaccttc tgtcaattcc tgcgtgattc ctactgttaa
     4561 gttagaagct actgtccaat aacaacctaa aatcagtccc ataaaaatca atgcttgtat
     4621 cctacctaga tcaggaaagc aaaacagtaa aatccaaaaa gcggtagctg cttgttgaac
     4681 ctgaacgttt ccggtagtga aaacggaacg cagtttcgta tatttctgaa aacggactaa
     4741 taagatattt aaaacaaatg caatcagtaa taaaatcatc acatctccaa aggtacggcc
     4801 aaatgtctcc attaatccag catccacagc attttgtcca aaataaggat ctgtaaccat
     4861 ggcatccaaa ttgaaccgtt cctttagtcc aaccaagatt ggccgaaaat tattgaccaa
     4921 accaccagag ccaacagtca aaataaagta accgaccgtt gcctttaaga atccagcgat
     4981 gcattcatga agcgggcgtt tcagcaaaat atagcctaat aacacgataa aaccaatcag
     5041 gtatgctggc tgcgtcaaga tatttgttgc aaaatacgtc caaatgctta acaaaaattc
     5101 ccccatcttt tttctcctct atcaattaat tatattctgc catcacaact tggtaatcat
     5161 cgatggagtt cgtagagatg agacgctcaa ccaatccatc tgtcattaat aattcggata
     5221 atttttggat attttctaga tgttcttctg gatcttttgc tgcgagtgta aaaaacaaac
     5281 tagccgtttt ctcctcattc tccccttcac tttcaaaacg gattggctgt ttcaacttgg
     5341 taaatgaaat agctgttcca aaaacaccat cacttttttc tgaagaatgc ggcattgcta
     5401 cttgaggtgc gatcacaata taaggaccgt atttttctac acaatggatg atctcctcca
     5461 catacgtttc atcaataatt tccttatcga tcaatacaag acagctttcg gcgatagctt
     5521 cacgccaatc cgtgatttct ttatctgggt aatgaatcaa ttgatggtca aaaaagtatt
     5581 tcagcaagaa actccccttc tttcttataa aaacgacgga aacggtgtat cattttcaat
     5641 cgagaagaca tcttcaaatc ctcgataaaa attaaactca agatcatctt tgtttgtcgg
     5701 atagatgaat ttcccgccta cttgccagat ataaggttta aatccatact tcaggcgatc
     5761 ctttttgaat ttccaaattt cagtgatctc ttttggatca gccataaaat tagaccaaat
     5821 atcgtagtgg acaggaatca ctacttttgc attcaatgac tccgccatgc gcagcatatc
     5881 aacagaagta actttgtctg ttatccctcg tgggttttca ccataggccc ctaaacagac
     5941 atcgattttg tgttcattac catgtttggc aaataaattg gagtaatgtg aatctcctgc
     6001 atgataaaga ttccctcctg atgtttcgaa taaatagttt actgcaattt gatccatctc
     6061 ctgaggcatt tttcctttta atacctcttc tggatcttca caagtgacca acgctgtccg
     6121 atcaaacgct tctaaagcta ctacattgat gtctttgatt ttgactgcat cacctggctt
     6181 tactgtaatc gttttttctt caggaattcc ccatttttgc cacgtgcgaa ccacttcttt
     6241 tggcccaatg aatgttgctt caggacaatt ttgatgaact gctgcggctg tatggatatc
     6301 tagatgatcg gaatggatat gtgtaacgat taaagcgtct acatttttta tcgcaaaagg
     6361 atcgattacg aaaggctgag tacgtaaatt aggctgcata ttttgaacgc cactcatacg
     6421 catcatctga tggccttttt tcatcatgcc attcccatga ctacgttttc ccgtcccaca
     6481 ccatagatca cataaaatat tcgttccttc atgacttttc agccaaattc ccgtacagcc
     6541 cagccaccac atagcaaaag ttccaggatc cactacttct gtttcgattt cttcattcaa
     6601 gtatgtgccc cactcaggaa atgtttctac taaccacttt tcttttgtta cttcattgac
     6661 agttttactc atttgcttgc tccccccata tcgttgttcc aacttacaag taaatattaa
     6721 tgtgtatcag catccatgaa aaccctttta tatgaccgtt tgttttttat atgattttct
     6781 ttcagtaatc aatgattgtt tcagtataat aaagacagat atgaatgttt aaatgaacaa
     6841 ctagtcaaat aaatccatgg atcaagatgt ccctcaggag gcaaaagtca tgaaaaactc
     6901 acttgtcaat attgaaaaac gtcaaaaaga aattttggaa ctgcttcagc agactgaaca
     6961 actatcaact ttcgaattag ctgaatccct tgatgtatct attagtacga tacgaagaga
     7021 tttaaattta ttagaagaaa aaaacgagat catacgcaat tacggttatt gttcttataa
     7081 ttacaaaaac cagactgatt ttgatcaatc tggtcctgaa aggattaaac aagcgattgc
     7141 cagagaagct agtaaataca ttaacgatta tgatacgctg tttatcaatt ctagctcgac
     7201 tgcgttgaaa acactggatt ttcttcaatc taaccatttg acagtcatta caaacaacgt
     7261 gaaaatcaat tactctccgc acaaagataa ttgtagttat attttaactg gtggagagat
     7321 gcgctttcca aaagaagcac tagtgggcga catcgcatta aatacgattt cttcagtcaa
     7381 tgcagacatt tgtatcattg gctgtagcgg agtcgatgta gtacatgggg tcacaacaaa
     7441 gatattaaat gaatcaacga tcaacgaaat gatggtcaac aagacaatca aatgtaagat
     7501 tttagtcgct gatcatcgaa aaatcggact gacatcaaag ttcaagattg ctgatatttc
     7561 agtctttgat tatttgatca ctgataaatt ttgttctgaa aaagtattag aggagatcag
     7621 aaatacgggg ataaaaacca ttcaagtaga ttcattttaa gaaccaggac gtaaatatgt
     7681 aaataggatt atcaaaaaaa tgaataacaa atttatcgat aaatgaaaaa cacgctacgc
     7741 tcaaattgat aaaggaatcc caagatgtat ccatccaatc gataccatca taatctattg
     7801 cttcttttat aaccgttata tgttgcctaa ataggaatca aacaatatcg aaaaaaggag
     7861 gtatgacaaa agtcacacct ccttttttcg aataaacggt attcaaatca gaacactgat
     7921 ttcacaacca ctttatttca ggtcgttttc aatcaccttt accgcgtaat catttccgtt
     7981 gaaacgcgct attttttttg cgtccatata tctttctaaa taatcatctt ctcctaattg
     8041 cttatggcaa gaagcaattt cataaagcaa gtattccaat gcataagtcg atttatgttt
     8101 cttattatac tcaataccct tctcacataa ttggattgct ttatcataat cctcgatttt
     8161 acggtaatag gtggcgatat cataatatac aatgcagacc atcagattat caaaatcagt
     8221 ctcactcaat attttaagtg tacgctccac ataaactttc gcaaaatcta attctccttt
     8281 tgacaagtag atcattgcca cgtttgcagc tgcttgtaag tgatggatat ctgtttcggt
     8341 cgtttgttcc aacacttgat taaaataaaa taatgctgca tctggttttt tcgcataaag
     8401 atgatcaagc agtccttgat aaaataaaat ttgatttaaa agatcagaat tacttacttt
     8461 ttcctgatcg atcgtttgta aaattttata agattcttgg tattttgata cagaattcaa
     8521 tgattgaatc tcatttattt ttttcctgat tttgtcttct tctgtttcta ctaatatatc
     8581 ggagatctcg acattcagct ttttgcaaag cgcacttaag atattgatgc ctggcgacat
     8641 attcttgttt tcgatattgc tgacagttgc ttgttcacaa atgccttctg ctaattgtac
     8701 ttgtgttaac ccctttttct ttcggtattc ttttagtaat gctccatcta ctttaatcaa
     8761 aacaatttcc ttccctttaa aaaattattt ctcctttata tcatacacaa aaaaaagttc
     8821 taaacaacca aaaatgttta gaacagaata aaaattttaa ttttaaaata atattcaaat
     8881 taaacaactg gcgtatctgc tccttgattt ctttttgtgt tatctgaata attatcgttt
     8941 acagttataa cacatagtga aaattgtcat ggcgagaaag tctaagaata tttttaaaca
     9001 taactatttc tttcttacgt gtgtataatg acgacagcac acctatcaat taatataatt
     9061 attttatttt tttatgttct catgtttatt tttaatgaca caacttctcg tatttatctg
     9121 gcacaacata taaatcgatc aaaaaattgt tgcgtgtttt tttgaaaatt ggagtttcaa
     9181 cttgattaca aaatttaaat ttagaagttg tgaaaacagc gagagacagt ttaatattca
     9241 aaatatacat aggctactcg aacgctgtgt tttttagtat actagtaaga aacgaaggga
     9301 tagactcatt ccaataagga ggatttcatg aagacaattc tttttgctcc tgcagtattc
     9361 aatttagctg agacaacacg aatgattgag gttgccaaag ctatgaaaga ccgttattac
     9421 tgtgtattct ttggcttttc taaaactttt gctcctttga tcacagaaag tggctttgag
     9481 tatcatttac tagcgccgat ccttacgaaa aaacaagaag aacaaatcat aaaatttgac
     9541 cagttgcgta cacttaaaaa cccttttacc aaagaaatgg ttgcctctcg tatcactagt
     9601 gaacagagtc tgattgctaa gtttgagcct cgactgattg tgacaggttc gaatgtgaca
     9661 atttttttat cggcccgcaa taaaaagatt cctttagtat atgttaaacc ctatgctttg
     9721 agtgaacctt tttttcaatc agagcatgcg ctgatgcccc acgagttacg tttcttcggc
     9781 cctttaagca atcccctttg gcactggaca aaaaagcgta tagtaaatac ccgatggatc
     9841 cccaatgcct tcaaacacgc tgcacaaaaa gaaatgcttc ctttaccaaa aacaagttta
     9901 caaatgatgg atgctgatct aaatctcatc acaacgccta aactattttt ggaagaagaa
     9961 cagctgccgg aaaattatcg aatcgttggt ccaatttttg ctaagctcag tacttccttg
    10021 cctgaagaag tgctaacttt tatacagcga aagcaacaag aaagaaaacg tattatctat
    10081 ttcgcaatgg gtagttcagg caatccgcgt atgttacgca aaattttgtt cttcttacaa
    10141 aaacaaccgg atctagcggt tattgcacct attgactatc tgcttgatga cattcaatct
    10201 gactcagaag atcttttaat aacagaatat ctgtctagtc atcttttgca tgaattcatt
    10261 gatttttctt ttatccacgg cggggaaggg accgtccaaa ctgcctgtga atccggcaaa
    10321 ccgtttatcg gtgtggggat gcaatttgag caaagctgta atattgacta ttgtgtaaaa
    10381 tacggaaacg caatcgccct cacaaaacca gtgactgaaa gaaaactgca gattgctctg
    10441 cgcgaagttt cttcacccaa gattcgtcag caggcacgca cgctgcaagc cgtttttcca
    10501 ataaatggtc cacaacaagc aattcaagaa atcgaaacct tcctgagcaa ccacccaata
    10561 tagtttcaag tagaaaaagc ttttttaata gagactcatc agtaatttcg ctattcgaga
    10621 cccagacagt gaaaatacaa aaaaagtaaa tagtggattg aaaagttaga gttacttaaa
    10681 ttacggtgtc taaaaaacac aaaatcatcc ttaaaataaa agatctgacg ctatccaaat
    10741 gagcataggt agcgtctgcc atttattctt agtcaaattc tttgacacct ttctctggtt
    10801 ggatcatctc aacgtttctt caaaagaaag accataataa ttaggcaaat acattttctt
    10861 aaaatgtgtc atatagatct agaagcatcg ctttgtagag atttgtgccg ctagtcccct
    10921 caacaattac taaatcaaat gtaggattta ccactttatc tttgataatc aacctccctc
    10981 ttctgttgag acaatgatct cgcaatccga tgcatactcc tatataaact gccagcaatc
    11041 cccacatatt gagtagatca tgtcagaatg ttctatgtcg tcagcaacga tacactaaaa
    11101 gtcacgttca ccatgactga ttgctattcc cagcacaatt atttctatac acgtttcatg
    11161 atttgaataa acactcacat catacatatt accattcata caccatactg cagcccctac
    11221 tatatggttg taagctccca aatctatatt tgacttgatc actttggtag tagatctact
    11281 aattctaaat ccattgctga taaaatttcc attttttcct ccttctttct gccaaaacag
    11341 ttaaaacaat aataatcttt atgtaaaaaa gggctgtgac aaaagccttg tcacagtccc
    11401 atattccgaa taaacggtgg tcaaaagctt gcatctgcgg taataagttc aaccaaacga
    11461 aaaataagcc aacatttcac aaaaatttaa gaagcaattt tcgtaaattt cttcttattt
    11521 cttgaagcta accacttctg ttacaaccac ttttagaaca tttaaagctt cgatgtgaca
    11581 aaccatctat gctgctcgat cataaaattg atagcaaaaa ttccacaaag tacatatgtc
    11641 ccccatgaaa acaaaacatt catatgcggt acaatgatct ttggaagaat cacgatcaaa
    11701 aatgatgcca gtgcccaaat ccatcgattg atttgaatat gatatgtagc tagcatattc
    11761 aatataaggt gactagccgt taataaaaag ataaaaacaa aaaataaaat cagccaatac
    11821 attgtttccc accttctaaa aaccaaactt agacagtctg gacttcgttt tctccacgac
    11881 tttgttcatc tgacagcatc tttttatcat aagcttttac aaatggataa tagataataa
    11941 atgctatcaa tgtgttgatc atgatcaaga taacaacacg ccagtcattt cctgctgaaa
    12001 gataaccgcc gattggagct ggtaatgtcc atgttggcaa aacagtaaat ctattgacca
    12061 tttctaattt gactgcaaaa taactgataa tagtcaaaac taaaggaact aagttgaacg
    12121 ggatgaacat gtaaggattc aacatcatag gagctccaaa aattatgggc tcattgatat
    12181 tgaagatacc aggaataata gaaaaacgac caacctcttt caagaatttt gatttacaga
    12241 agaatataaa caaaacagat accacgatcg ttgctcctgc accaccaatt gttaccgtcc
    12301 attgataaaa ctgttcagga gcgatatagg gtaattgggt ggcagctgta ccatctgcca
    12361 atgcctttgc attctcatcc aacatgatca gccacattgg acgaacaaca gcccctacaa
    12421 tactcatgcc atggatacca aatgaccaca acaaatggat caaaaacatt ggtagtaaaa
    12481 caccaagcaa attattccct aaaatattgg ttaaaggctc gaataacgat aataaggcag
    12541 cgtttacatc aaagcccgcg acgcttcgaa tcagccaagt aattgttaaa atgactgcac
    12601 ctggaatcaa tgcctcaaaa ctacgggcaa cagcaggtgg cacttgttct ggcattttga
    12661 tagtaatatt tcgattttta aagaaacgat atacttccac tgcaaaaatc atagataaga
    12721 tccccgcaaa catcccagat gctcccaaag aactcatagg taagacccag ccaagaggtg
    12781 cctcttcagg agttaaaacg tttacaggaa cttgtaacat aaagaacgtt cctaaagata
    12841 atataccacc tgtcacacta tctaatccat atgatttagc tagatccgaa cccataacaa
    12901 aagttgcata aatagccatc aatcccatcg tcatcctaaa gggtaaaaca atcgttgccg
    12961 aataaggggc aataaattca ttccatccag gaaacggtaa attgataaag accataaaaa
    13021 atgtcccaat caaaatcaat gacaatgttg aaacaacccc attacgaatt gctaataaat
    13081 gacgctgtgt accaattttt gccattggtg ggacaagttt ctcttcgacc catttcatca
    13141 gcttttccac taaaaccact ccttttcaat aaaatatgaa ccattcattg catgacaacg
    13201 caaagaatgt tcataactaa ttatataatt aagaaatttt atttcaatat attctcttaa
    13261 ataatcaaat ttatttttaa gaatcctgaa aataagtttt ctaaatcata ggagcaacaa
    13321 aaaaattcga taattaacaa aaatcaaaat gattaaatct agtgattgaa acatatcatt
    13381 tcaaaaaaat tttgtaaatt cacccataaa tatcacccta tttaactttt ttcatcgtac
    13441 actaaaattc aaaacaacta tctttaatct ttacttcttg gttttgtttt aataaatttc
    13501 cttcaaaaat gcctggagaa actacaatga tcaccgtatc tttttgtgct tgctccaact
    13561 tcttcaaatc tataatagct aacagtgtcc cttcttttac ctcctggtta ctttcaaccc
    13621 gtatctgaaa cggacttcct tcgagttcaa ctgtatctaa acccatatgg atcagtattt
    13681 ttctgccaga ttcactttcg atcgttatgg catgtcgggt aggaaatata ttatcgatta
    13741 ttcctttaac tggcgcatgg atatatccat catgattcgt tatagcgtat ccaactccta
    13801 tcatttttga agaaaagacc tcgtctttta ctgctgttaa tggaataatt tgaccactag
    13861 ctacagcttt tagaatgttt cttgttttaa agaaatgcac tttttatcac ctctacttta
    13921 atgctggcca atattttttg tttactttga tcatttcatc tagtattttt tttgcgactc
    13981 tggcatttgg tacggtttga ttcaatgtaa atgcttgtaa agctttttga taagaacctt
    14041 caaagtaagc atctactagt aacttctcta ctgcaacttg tgcctccatc aatcctttat
    14101 gaaaatcact gattggtttt cttagtgtaa ttggctccac accagttgca ccaacatatg
    14161 ccggtatttc aacaactgca tctgaccgta gattcggaat cgccccttga ttaggaacga
    14221 ttagcataaa gcgacgacga tcatcattca acaaggaaat agctatatcg acgatatatt
    14281 gtccatgctc cccaaaatta aagttcaata cttcttccac aataccgcgg cgtattttat
    14341 cagccatttc tttggtattt ttctctcgtc catccatgac catattagca cgtgtatact
    14401 ctttgtcagt atgctcaacg accatatcag gatataagta atactctaag taattattcg
    14461 ggatattact tggaaaattt ttcgtgatga ctgacatcat ttgaaaggtt ttttgccaag
    14521 ttttatctcc tatattaaaa tcggcgactt gcatttcttt tgttattagt ttttcaataa
    14581 tctctggcat aatttctcgt tgcaattctt tatcataaat cgatgtatac cagccaaagt
    14641 ggtttaaacc ataatacgta acgatccaat tcttacgatc ataaccgtaa ttcactgcaa
    14701 tcgtttcttc aattgaaata gtcatatcac aggcattaat catttttaca ttcggatatt
    14761 tacgacgaac agcttcagaa acgatcgact ctggatttgt ataattcaaa atccatgctt
    14821 tgggggcata gtcttgtata tgatcgacaa tttccaataa acctttgatt gagcgcatcc
    14881 cataagcaaa tcctccgagt ccacacgttt cttgtcctac taatccatgt ttaagtggaa
    14941 tcttttcgtc cttttctcgc atctccaatc ctccaacacg aatttgtgag aaaacaaaat
    15001 cgcatcctgt aaaagcaagc tttggatcat ccgttgcacg aatgcgaata tttgaaaaac
    15061 cttttctttt cagcataaat ttaacaatca agtacatatc catatttctt tcttcatcaa
    15121 tatcatataa acgtatttca gataatggca accgtttttc attgttcaaa atggcttgaa
    15181 cgattcctgg tgtatacgta ctcccgcctc cagctatagt gataatctgt tttttcatca
    15241 tcatcttttc ctttctattc ttctaataat ttattgaatt ctgccataac ataagtcact
    15301 tctaagccga tgataatttg ataatttttt tcagttggtt taatgatccc gcttatccct
    15361 aattgcttga ttcgctgttc ctcgaccatg gtgggatcca ctacctctac ccgtaggcgt
    15421 gtattacaac tatagacatc caggatattg gcttttcctc caaacgcttg tagcattttt
    15481 gttgccatat attcataatt tttacttgct aaccctaact ctgtttcttc taaggttact
    15541 tcattgccaa actctgcctt agcttcacgt cctaatgtct gaatgtttct cttattgatc
    15601 aaataataaa aagtaacgta atacaaggca aaaaagaaaa ttccgattgg aagaatcaaa
    15661 atagcattgg tagcgattcg aaaattgatg agataatcaa caatacatgc tccgaatgta
    15721 aaaccaattc gtatattgaa taagtaacag acaatccctg ctaaaccggc aaaaagtgca
    15781 tggatcacgt acaacatagg agaaagaaac atgaaactaa attcaacagg ctcagtgata
    15841 tttgcaataa atgaagttcc tgcaccgctt cccatgattc ctttgaccat ctctttattt
    15901 tctttataag ctgctttata gatagctaga catatagctg gtataccaaa catcattact
    15961 acaaaaaaaa ctgataaaaa cagtccagcc tgaggatctc cgttgataaa gcgtgtcatc
    16021 tctcctctga aaacttcctt gctaggagat gtatagcttc ctaaatcgta ataaatatac
    16081 gtattcaaca catggtgcag tccaaagggg atcagcaaac gattcaaaaa cataaatatc
    16141 cccacaccta atgctcccat atcaacgagc agttttgcaa aattatcaat cccaatttgg
    16201 atgagcggcc agataaagcc caaaaaaaca gctgcgattg tttgtagaat catcaccata
    16261 gtcaatggga atttttcgcc cgcaaaataa gaaaaaacta ctggtaattt ttgttcttta
    16321 aagcgattat acgtccatgc cgctactaaa ccggaaataa ttccaccaaa aatccccata
    16381 ttcacttctg ggtccataat ttctaagcct tttttcaagg tagcaatcgc taaaaaacca
    16441 gtaagtgcag gtattccttt gtccttattt ttgacaaaac cgattgcaac tcctatagca
    16501 aataagatat ccaagtttcc aaaaacggca tttccagctg caccaattac tgggatgttc
    16561 agcatatcgt cagctgataa acgcatgatc aatcccgcta atggcatcgc tgcaactgga
    16621 agtagcatcg ctcttccaag cttctgcaca tttgatttaa cattcatttt tattcctcct
    16681 ctattaaata tcctcatatg ttactaactc aatcaaagga tcatttttca ctttttgagc
    16741 aaatgctgaa tgaattaaaa attcgacttg gtgggtacga ggatacacaa aacttgaacc
    16801 atttaacaat tcctgatcca aatacgctgc gtgacacatg acttcgatcg ttttatcttc
    16861 tctcaatatc atgagtaaac ttgccaaata ttcttccaca ctcgtattga tttgtcgttt
    16921 tttttcatca gtttctccta cgacatcgaa acaaggctca aaataatcga catgacgaac
    16981 ttcatctttt cgttcaaagt tgctccgaac cggcaaatca tatttttttg ctaatgtaac
    17041 aactacctcc tgattttcat ccaaagtatg agtatgatga tgactgtcta aatgagttgg
    17101 tatgatcccc gcatgataaa ttttttgaat ctgagcattc cattcctgat acagttgatc
    17161 tttgtcaatg ttaaatggat gctgataata agataaggat ctgaactctc cgctttcgat
    17221 aagagtatcg acagttttga ggagtggttt gccacacgtc aatgttaaat ggactcctac
    17281 acctagccta ggcatttcct ttcttagttt cacagcatgc tcgaaacccg gcatatttgc
    17341 catcaatgta gttgatgtca aaattcctcg ctgataagca tccataatcc cataattcac
    17401 accatggcta tagccaaaat catccgaatt aaaaatcact tttcccattt cattctcctt
    17461 cttttttcta ctaaaatagg cgcaaccaaa taatcatagt ccatttacta tgtgtcattt
    17521 ggttgcgcct atagatagtt acgcccttat tttaatagat tcttgctaga tgaattgcca
    17581 aatagatgat ttcattttct tgaatggcaa gttgaaattg ctgttcgatg atatctttaa
    17641 tctttagtgc tgtacaatac gctttgctat gtttaaatgt ttcagtaaaa aaaccaatat
    17701 tttctactgg cgtttcttcc tgataaatca agcgtttaac caggaatttg atatgaacca
    17761 ttaagcgatg ataagtcagt gattctttat cataaacgtt tgaataggat ttttctagat
    17821 gggacaaaat cgtggtcgtc atttctacta tttttaagct ctttaaacta ttaggctctc
    17881 ctagctcagc attaatgata tgcatagtga tgaatcctac ttcatttgac cctaactcgg
    17941 tttgatatcg atgattgatt cgctcgacca cttctactgc tatatcatat tcatttggat
    18001 aaaggaatct catttctggc aacataattg ctgtgacatc tctatcttct ctttttcgtt
    18061 gaatagcaaa ataaatatga tctgtcaatg taatatagat atttgaatct aatggagagg
    18121 agatcctagc tgttatcagt tcaatcactt cttccgcaaa atccataaat tcgattggaa
    18181 tctgcgagac tatctcactg aatcgtttga tcttttcttt agaatctaat acaaataatt
    18241 tgtcagcatc ctcaacatca aatggcttac tcactttagc agaaaagcca atccctttcc
    18301 ccatcgcaat tttttctatt ccatcgtcat cgatcaatac agcattatga ttcagctttt
    18361 tcatcacata caccgttaat tcacctcctc tatatgataa aacaaaacaa cttgcagact
    18421 ccttcataca tatttttgtc tccaaacaat ttttaaagac aaaaaacgac ctaagaaaga
    18481 accctttctt aggtcgtgcc taattgaata gtagcaccct acataattta caaaaatagt
    18541 ttaacacata ataaaagcgt tatcaatatc ttttttactc gttttatgat aatacttgta
    18601 tcgaattgat ttggaggtaa ttacataaaa acaaaaaaaa tatagcaact ctctataaga
    18661 aagttgctat attgataatt ataccggcgg ccggggtcga accggcacgt cctcaacgga
    18721 cactggattt tgagtccagc gcgtctgcca attccgccac gccggcaaat ttaaaaataa
    18781 taactggggt agctggattc gaaccaacgc atgagggagt caaagtccct tgccttaccg
    18841 cttggctata ccccaagaat aaagggcgaa tgatgggaat cgaacccacg aatgccggag
    18901 ccacaatccg gtgcgttaac cacttcgcca cattcgccat cataaaagat gttatttaat
    18961 ttctcaataa aaaactaaga tgaagacatc ttagtcaata ccggcggccg gggtcgaacc
    19021 ggcacgccct caacgggcac tggattttga gtccagcgcg tctgccaatt ccgccacgcc
    19081 ggcaagttga tttattagta ctaaggcggt aaccggattt gaaccggtga tgaaggtttt
    19141 gcagacctct gccttaccac ttggctatac cgccattata ctattatcaa tctataaaat
    19201 aaagaataaa ttatagaaac tggggtagct ggattcgaac caacgcatga gggagtcaaa
    19261 gtcccttgcc ttaccgcttg gctatacccc aagaataaaa agggcgaatg atgggaatcg
    19321 aacccacgaa tgccggagcc acaatccggt gcgttaacca cttcgccaca ttcgccatgg
    19381 caggggcagc aggaattgaa cccacactaa cggttttgga gaccgctgtt ctacctttaa
    19441 actatgcccc tataaaatgg aggagagtgg attcgaacca ctgaacccta aggaacggat
    19501 ttacagtccg tcgcgtttag ccacttcgct actcctccat ggtggcgcgg gacagaatcg
    19561 aactgccgac acacggagct tcaatccgtt gctctaccaa ctgagctacc gcgccatatt
    19621 ttaaaattat taattgaata acaagaacga cggttccgac gggaatcgaa cccgcgatct
    19681 cctgcgtgac aggcaggcat gttaacccct acaccacgga accagttcat tatggaggtt
    19741 aacgggatcg aaccgctgac cctctgcttg taaggcagat gctctcccag ctgagctaaa
    19801 cctccaacat tcaattaaaa tgacccgtac gggattcgaa cccgtgttac cgccgtgaaa
    19861 gggcggtgtc ttaaccgctt gaccaacggg ccaggtaaat ttgctacgga gagtaaggga
    19921 ttcgaaccct tgagacagtt tggcaccatc tacatgattt ccaatcatgc tccttcggcc
    19981 tctcggacaa ctctccagag tgaaagaagc tcaatactct ttctcaaaat gag
//
LOCUS       DACBYO010000049        19613 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.049, whole genome shotgun sequence.
ACCESSION   DACBYO010000049 DACBYO010000000
VERSION     DACBYO010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.049"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..719)
                     /locus_tag="IVD26_001729"
     CDS             complement(<1..719)
                     /locus_tag="IVD26_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAP6079678.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMV"
     gene            904..1743
                     /locus_tag="IVD26_001730"
     CDS             904..1743
                     /locus_tag="IVD26_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP6079679.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            1939..2913
                     /gene="sgrA"
                     /locus_tag="IVD26_001731"
     CDS             1939..2913
                     /gene="sgrA"
                     /locus_tag="IVD26_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAP6079680.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            3211..3567
                     /locus_tag="IVD26_001732"
     CDS             3211..3567
                     /locus_tag="IVD26_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079681.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            3570..4727
                     /locus_tag="IVD26_001733"
     CDS             3570..4727
                     /locus_tag="IVD26_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079682.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(4753..5193)
                     /locus_tag="IVD26_001734"
     CDS             complement(4753..5193)
                     /locus_tag="IVD26_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP6079683.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            5353..5859
                     /locus_tag="IVD26_001735"
     CDS             5353..5859
                     /locus_tag="IVD26_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP6079684.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            6027..7940
                     /locus_tag="IVD26_001736"
     CDS             6027..7940
                     /locus_tag="IVD26_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAP6079685.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            7945..8946
                     /locus_tag="IVD26_001737"
     CDS             7945..8946
                     /locus_tag="IVD26_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6079686.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(9148..9354)
                     /locus_tag="IVD26_001738"
     CDS             complement(9148..9354)
                     /locus_tag="IVD26_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAP6079687.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(10000..10848)
                     /locus_tag="IVD26_001739"
     CDS             complement(10000..10848)
                     /locus_tag="IVD26_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP6079688.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            11012..11914
                     /gene="gnd"
                     /locus_tag="IVD26_001740"
     CDS             11012..11914
                     /gene="gnd"
                     /locus_tag="IVD26_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAP6079689.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            11916..12917
                     /locus_tag="IVD26_001741"
     CDS             11916..12917
                     /locus_tag="IVD26_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAP6079690.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFNVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMCEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            12914..13198
                     /locus_tag="IVD26_001742"
     CDS             12914..13198
                     /locus_tag="IVD26_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP6079691.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            13231..14028
                     /locus_tag="IVD26_001743"
     CDS             13231..14028
                     /locus_tag="IVD26_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP6079692.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLSSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            14042..14875
                     /locus_tag="IVD26_001744"
     CDS             14042..14875
                     /locus_tag="IVD26_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6079693.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            14893..15750
                     /locus_tag="IVD26_001745"
     CDS             14893..15750
                     /locus_tag="IVD26_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP6079694.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            15772..16281
                     /locus_tag="IVD26_001746"
     CDS             15772..16281
                     /locus_tag="IVD26_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6079695.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            16318..16719
                     /locus_tag="IVD26_001747"
     CDS             16318..16719
                     /locus_tag="IVD26_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079696.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            16831..17184
                     /locus_tag="IVD26_001748"
     CDS             16831..17184
                     /locus_tag="IVD26_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079697.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            17218..17661
                     /locus_tag="IVD26_001749"
     CDS             17218..17661
                     /locus_tag="IVD26_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP6079698.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            17678..18763
                     /gene="uxuA"
                     /locus_tag="IVD26_001750"
     CDS             17678..18763
                     /gene="uxuA"
                     /locus_tag="IVD26_001750"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP6079699.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            18756..19469
                     /locus_tag="IVD26_001751"
     CDS             18756..19469
                     /locus_tag="IVD26_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP6079700.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         6717 a         3022 c         4124 g         5750 t
ORIGIN      
        1 tttaccattt ttactagata atagctttgc tgataagtcg ttggatctgt tacaggaatg
       61 atatcagaaa cttccccgtt ttttagttta aatgctgctt tttttacttc agtaggaatc
      121 tctggattgg ttgaatcaaa attcattttt ccatcagttt cctttaatgt tttatttttt
      181 ccataagctt gaacaagctt ggagaaattt tctccttcat ttgcttcttt ttttgcttta
      241 tctgcttctt ctttagtcga aaatagaatg atctgtgtac taacttctgg atagaattct
      301 ttccaagcag tgtctagatc tttatctgtt aattttacat tggctttcaa accgtattgg
      361 aaagccagca tctgtttaaa gagtttctta tatgtctctt ctgtttggcc aactgctttt
      421 aattgttcct tgtagtttgg accgagtttt ttgatttgtt cattatattc ttttgttact
      481 tcctttgaag aaatctcttt tccgtataca tcatcaaatg ctttgaagac aatcattttt
      541 tttaatagtg tttgattatt tgatttaact tttgggttat cataaaaatc ctgaactgta
      601 agtgttccac ctttaaacgt tgcaatcgtt tcattggact tgctacaacc tgagaatagt
      661 aaaattgcac atgctgaaag gcacataatt agtagttgtt ttttcaaaaa atttcccatc
      721 ctttccttat taaaaacagt ctaacagaag aattagggag acagtctttc attttcgtaa
      781 ggttgctgta gatattctta gttcgtaaaa atctattctc tctatgatgg agaacattta
      841 catagttttc acgagacaag aaagaaaagg gttgttaaac ttaatataaa ggagggatga
      901 aagatgatca ggattattcg gttgattgga tctgttttaa tagtcttagt tggttttgtt
      961 ttaggaattc ttgtcaataa tgcacttgcg gatatgttta ttggaaatag tgaatggatt
     1021 ggagcaattg ccggtacggt cggacattta gctgtttttt tactagcttt atttcttgct
     1081 agtaaggtcg aaggaaaaag aatagaagat tatggtgttt ctgttcgagg aaaagactgg
     1141 gggtatttag cgggaggtct cgttgttgga attggagtgt ttctgcttat tactagtcca
     1201 ttatatttga cgggggcgta tcggttagat tcaggaaacg caaacattgt gccgctgata
     1261 acgagtttta ttttatttat tgcagtgggg gcatcagaag agcttttatt ccgtggcttt
     1321 tttcagcatc agatgcttag atttggtccg ttaatagcaa tgattggatc tgctgcatta
     1381 tttgctcttt tgcacggatt gaatcctaac atgacatttc tggcagtttt caatatcttt
     1441 ttagcaggtt gctttttcag cgcacttatc tacagtacag gaagtttatt tacggctatt
     1501 ggtgctcata ttacttggaa ttggacacaa ggagctattt tgggtatacc agtcagcgga
     1561 acgcaagaac aaggtttttt ctccactctg atccaatcgc aaaatacaat aattactggg
     1621 ggaaactttg gggctgaagc atctatatca actacattat tcttgttagt cttgattgtt
     1681 ggtttgttac tctatgcata taaaacaaag cggatgaaga aatacactgc tgtttatcaa
     1741 taaaagatga agaaagcaag gctgatatcg gtcttgcttt tttaagtctg tcattgatta
     1801 aacgaaaaag taaacaaatt caagcgaata cacgacatct tttgttagat tttcacaact
     1861 gactgtcgtg ttctcatcat tttcatttta tataattcct ttatcaaata gaaggtaatt
     1921 atatggagag tgatagaaat gaagaaaaca gcgaccgtat tatttgttat tcttgggctg
     1981 agtataattg cagcaatgat tggaatcagt acttctgcaa atgaacgggc aaatgagaat
     2041 ctttcattta ctgtgaaaac tgatcggatt gtttatgaca tgacacaaca agtcattact
     2101 attccagtca aaccaaacaa aagcgtgaat gctagtgatg tacatgctgt tctaacatat
     2161 ggttgggatg gtaatggaag ttcagaaaaa gttattgggg aagtttattt aaaagacgta
     2221 caatggaccg ctggtattga gtatacaata atgatttctg cagaactatc gattgatgag
     2281 atcaagagta aagataaagt tgatttgatt gttttttatg atggacagat gacgatcacg
     2341 gagaatttga aaccaagcag ttggacagtt gttggaccgc caagcagtac ggatagcaca
     2401 agtagtgaaa gcagtacaga aaacacgagc ggtgaaagca gtacagagag tacgagcagt
     2461 gaaagtagca cagaaaacac gagcagcgaa agcagtacgg agagtacgag tagtgaaagt
     2521 agcacaggaa gcacgagcag cgaaagcagt acggagagta cgagtagtga aagtagcaca
     2581 ggaagcatga gtagtgagag tagcacagga agcacgagca gcgaaagcag cacaggaaaa
     2641 gtaaataatg aacttgattt ggtacctatc ataccaacta aggaacaaaa gagaaatgca
     2701 gggagcaacc taaaaagtgt gctaaaacag cctgattttg tttctcgtgg aattgatcat
     2761 caagaaaaag cgaaagaaac agataataga aaaagcgatt taccagaaac tggtagtaga
     2821 accttgaaca agctaattac atggatgggt gtgttactca ttttgattgt aggagcaagc
     2881 tattttcgtt ctctcttcca tcgagtgaaa taaagaataa aagcaacaga tctaaaattg
     2941 aataaaacga tagatttttg agtgaatatt tcattcgaga gtgctgtatt gcctggcgaa
     3001 gttgtagctt tgccagatct atttttgttt actaacatat ttgagaaaca ggaaataaca
     3061 ggaacacaaa tggaaaataa gagcaagaat aattgacaat gcacactgcg catggtagta
     3121 tctctgaaaa atcagtaacg aatctatttg tacgttattc atgtagctgt cggaataagt
     3181 ctaaataata gataaaaagg agtatgtact ttgtttgaag aatttattga tatcaatgaa
     3241 aggcaagtat atcaattttt gaactattgt tatgaaagag acgagaaatt atatgtggtg
     3301 aaggatatcg ctttagatct aaactacacc ctggctaaga tgaattcggt gattcaacaa
     3361 gcagaatcgt tttgcgaaag gtatccagaa tataaattat cttttctttc agaaaacaag
     3421 atgataaaag tcgagttttc ttctcagttt ttactgagta aagtttattc tatactttta
     3481 gagggaacga ttggttatat tttactggat tcactttaca aaggtactta tcaatcctta
     3541 gaaaatctta gtcaaaaaat tatataagtt tgcgtacgat tcaaagaaaa ttaagagaac
     3601 ttaatactat tttgaaaaac tatcatttat cttgcagctt gaaaaaaggt aatccgatag
     3661 aaggagaaga ataccgtatc cgatactttt ttcacttgat gtattggcag tcattcgacg
     3721 aaaatcattc tgatatatta tcaagtataa aaaataaacg tcaactatta gaaaaatttg
     3781 cgaaacatgc gccatatacg cgtagtatag atagaaagaa atggatcagc ctactaagaa
     3841 tttcgttgca acgaatgaaa caaggccact cgattacgta tgtcccagaa gagatgaaca
     3901 aatttgtgca tccattgata acaaaagaag agtttacgca ttacatacta gagccttttt
     3961 ttgaagcaaa cttctggtcg atgaatcaca tcactccaac agagcaagct tacctttatt
     4021 ttatgtttgg tgtaatgaac acctatttgg aagaagattt gttggatact ccagataaag
     4081 tacaagaaag ttggggctgg attgaatcgt ctattgtaga aaattttgaa aaaaacttca
     4141 agatttgttt tacaacttca gaaaaaaatt atctatatgt caatttggca atgatccatt
     4201 tgtattcaag ggtttttggg acaaaaaaga aggtggatgc ttttggaaaa tcagcagaag
     4261 acagagattt tcagcatata tttccagtga tgtatccaat catgcaacag ttttttagtg
     4321 gggtagctcg cagaattcca gagcttaata cttattatga aaagaacaga cggttgattt
     4381 ttcaatactg tatgttagtc agggatattt ttataaaaca cgaacaacct gtcatattct
     4441 atattcaatc aaagtatggt aaaacacagg aattatgggc aaagaaaagg atattatcta
     4501 tgactgaacg cccaataaaa tatagtgcat ccgctgatca gttacctgat attgtcatta
     4561 gcgattatcc tatcgacaaa aaggcatatg atcaaacgaa tacacagata ttttactgga
     4621 atggacaacc tacaaaaaat gattgggcgc gtctgaaagc tgaaatcata aaaatcagga
     4681 atgagaaaaa tagatccata ttggaaaaat tggatttcgt taattaagaa aagcagattg
     4741 tttatgccaa aattaagaca ttgcaaaaag attattttct ttaaaatcga caagatgacc
     4801 agaaagcaag agttcgttga gctcttgctt tcttttagtt ttagaaagga acatcctgat
     4861 tttatcttcg ctaaatccag tcaaaagttt tgcagattgg tcgtagataa tcggtttttt
     4921 caataaagaa ggggatgtac gaatctcaat atatagttca ctcaaactga gttcatctat
     4981 tctgtgaaca agatttttat aactaataga atgagtagag agcatttcgg tcacgccgtt
     5041 gtttgtcaat tttagtaagt ggataaattc atttttggtt agtggttgac gaattaagtt
     5101 ctgttcgata aacggtatat catggacgat aagccaacgt tttgcgcgtc ttgaagacga
     5161 gcagccagaa cctgtataca atttaatcat catacattcc tccaatagct aagtatttat
     5221 gaaataataa catgaagaaa tagtcgaaaa gtgccattta gaggtgtaaa ataagaaaat
     5281 gttgtcacgt ataatggaac tagctagata agaaatacta ttaaatcaag aaaaaagaaa
     5341 gaaggcacaa gtatgtcaaa cacagccgac gcaatagtag tgatcgattt acaaaaaggg
     5401 gtatgttttg attcttcgcc gatacacgaa ttagaaacag tgacagcatt agtgaataaa
     5461 agaatcaaaa catacgaaac gattgggaaa ccagttattt tcgttcaaca cgaagatgct
     5521 caattagtgc cacaaacaaa accatgggag ctattgtcgg aattatctat tcctgagcac
     5581 agttattttg tgagaaaaac ccatgcgaat tcattttata agactaattt gagtgtttta
     5641 ttaactgaat tggactgtca ttcgatcgaa ttatgtgggg cacaagcaga gtattgtata
     5701 gatacgactg tgaagtttgc tcatggatta ggataccagc ttatgatgtg tagaggagca
     5761 acgacaactt atgataatcc ttttatgaaa gcaaaggaaa caatcgcttt ttacgagaaa
     5821 atttgggata aacgatttct gacatttttg gagcaataag ttgtttcttc gtttaaaaaa
     5881 agcagaatgg atactggttt atccattctg ctttattacg taaaatgaga aaataatcct
     5941 gttctatttt tatgggataa accatttatt ttttgtataa aaaatgtttg cgtttacata
     6001 taattctcct agaaacataa aaaggagtga atagcttgag aacaaaacaa gtattaaagg
     6061 gagcgttggt catcttattt gctgtaagta caagcgtccc gcaatggaca gtatatggag
     6121 agagcatttc ttccgaatcg gaatctcggg aggtagaaac cacagaaact actgatgctg
     6181 gaaatgaaac gaaatcgagt acttcacaaa cagaaacaaa tactgaaaca acggttgaga
     6241 catctgttac tagcacagat caagaaacga ccgctaccac agataaccaa caaacagaag
     6301 aagcaacagc tacaaaaatg tcaaacgacg aatcctcttc tgctaaagta agtgacaaag
     6361 agaatgggac agaaaatgat gatatcggta aaggtgaaaa tttcaatggt aaagaatatt
     6421 tgaattactt cggtaaacag atgacagaaa tacttaatgg accaacagaa gacatcaagt
     6481 caaaattaat agagttatta gtcactgagc ttgctgttaa tgattatggt gtagataaag
     6541 agattatcaa acatctgatt gctacttatc tattgtacga tatcgctttt gcaaaaaaca
     6601 gtgtgttgat gtcgatgctt ggaggtacag atgatgggac aacgcctaca gaaaacacag
     6661 gcttctatcc aaatacaaaa caacttcatc aaactgtact aaacaaacaa gatggcaaaa
     6721 tgatggatgt atatgcatat tatgtcgatc aaggttcaga taaaacagtc atgatccatg
     6781 gcggatttcg agggaattgg aataacggga tcgttacaga agaatacaat gatttttata
     6841 aggccgggta taatttatta tttgttgatt ccagagcgac tggtaatagc ggaggcgatt
     6901 atgtgaccta tggacaatat gagtcagatg acgtccttta ctggataaat caagaagttc
     6961 gagagcggcc atctcaaaag attttacttt atggtggttc gatgggagca gctacgatga
     7021 tgtctgtatt agcgaaagat attcctgtca atgtcaaagg aattattgaa aattgcggat
     7081 ttgcatcaat tgatgaacaa ctacgtttta cgtacagcca gacagtagcc cccgcactac
     7141 cggatgccat aaaaaatcag ttagacatca ttggggatca agagcatgaa gatttattta
     7201 tgggcctttt gaaacaatac tattttgatc aggagatgca tttggataca aaagctgctc
     7261 tacctacgat tggaatgtca gattcattgc ctaaattgat tatccatgga acagcagatg
     7321 atgtagtacc tgtgtctaac gcgcaaaaat tatatgagtt atcaggaggg tataaagatc
     7381 ttttattagt agaaggagca gggcatggaa aggcacagga agttgaccat gctgcctaca
     7441 cgaaacatgt aacggacttt ttgaaagtag tgttccatga tcagataaac gtaaagtatg
     7501 tggatgaaaa caataaaagt ctactcaaag accaggacga aatccagctt tacggagctt
     7561 atggagaaaa ttatatgaca gagcaaaaga cattcgaagg atacgaatta gcaaatgttg
     7621 aaggaccgac tgaagggatt tttaatgaga cgataccaac tattattttc tattacaaaa
     7681 aaatcccagt agctccacca aaaaagcaag atccgacaga gaatgcagac aataagggaa
     7741 agaatgaacc tcgagaggat caatcaagtg atgatacgca accgattcag atgacagtga
     7801 aagtacaaaa aaagacagat gcaaaaaaaa gaatgttgcc gaaaactgga gaaaagaaac
     7861 attcgcttct catttattca ggtggatttt tatctgttag cacgattatc acatggattt
     7921 ggcgaagaaa gagagggtaa atgaatgaaa tggttcaagc gaatagtgat tgcagtacca
     7981 gttatcatcg tagttatttt agtcactgta tttttgatta atcaaatcac accaaagccg
     8041 attagcttgc ttgttagaaa acaatttgac acaagtgaaa aagaacaagt atatgcccga
     8101 ccagatgatt tccagcaaaa aatcgaacaa atcgatataa aaaaagaaat atcctatcct
     8161 tcaaagtaca aaaataataa tatggatatc tacacaccga aagtggaaaa gaaaaaatta
     8221 ccgattcttt tctggatgca tggaggcgca tatgtaggag gggataaaaa tgattgtcgt
     8281 gattatttgg aatatctatg ttcagacacg cagcaaatca tcgtaaatat agattatgaa
     8341 cgatcaccgg aagcaaaaca tcctacacca gttatccaat tgaacgaagc cattcaagca
     8401 gctaaaaaag agataaaaga tcaagcagat tggtcgaata tttcgattgg tggaaattcg
     8461 gcaggtgcac aaattagtgg agaatatttg ttagcacttc aaaatgaaga aattaaaaaa
     8521 gctgatcatc ttgatccgac tttggagaac aagcagatta cgaagtttat ttctttgtct
     8581 ggtctgttgg atccttctgc acttactcaa gtaagtgata aaatctctag ctttctttat
     8641 gaaaaatgtg gatgggctta ctttgataat aaggactttg aacaatcaga gaaggtcaaa
     8701 agtttagcct tggtcagaca tgcggatcgt tggacgcaaa acacattctt aacggatgga
     8761 aatacaaata cgtttacgaa acaaatggaa gaagtaactt ctgtatttga gaaagcgggg
     8821 gtgaaagtca caaaagtaga ttatgcggag aaaaatgctg ttttgaacca tgaatatcag
     8881 tttgatttca gcaataaaca agcgcaagaa acatatcaaa agttagtaat gtttttcaag
     8941 gagtaaagtc ttatgatgca aaagaggttg taatctgtca cttagctcca agtcacaagg
     9001 agcaatttca ataaacaagc ttttcatggt ttatgaatat tgtaacttgt gactgaggag
     9061 ttagagatgg caaggggcac cttttattcg aaatttggga atatcacacg attattgtca
     9121 cgatctcttt tacgtaaatt ttataagtca gatttgttgt tttgatcgtt taaaaaaagc
     9181 aacaaatccg aagcctgcgg aggcaagaag ggacaaaaag ccgagtggta agcaaaagaa
     9241 tgctggttcc actaatattc cgttgttatt gatataaggc tgggaacaaa gatgaatagc
     9301 aaataaaatc aatgcactag cgaaaaaaag caaagaaata tggatagctt tcataagcag
     9361 cacctccttt tttataattg tatgataaat agattaagaa tctataaatg tgacaagttt
     9421 gttaggatgt gaataaaatg atcatctagc gaacttgaaa caaagatggc taatgataag
     9481 caattaatga ttcagcaatc agataggtac aaagtttacc atcatacgtc tagaccaata
     9541 atagaaaata tgggaatata atagaaaaga tttaggatac ccccaaaaga atttccccaa
     9601 aaattcgatg tatcctaaac ttttttattt tacataacaa tcatatcaac tgtgaaataa
     9661 aattacaaat gataacctaa aatgaggcca aaagccagtg ttatcaagga aatacttaat
     9721 tcaccaaaat tttttttaat tttttagaaa ataagaaaca aaaataataa aaaaaagaaa
     9781 agataaattt tttactactg tatactaact ttgttatcgc atctaacaag taactcgaat
     9841 aataccaata caaccttctc caaagatgcg atgacatacg ttctaaccca ccgactattg
     9901 atgttctgta ccacccttgc agaaccaaaa aagccactac caaatatttg gtagtggctt
     9961 tttttgtttt atggattttt cgctttttct gttatggtgc tattctttga tttcagaaat
    10021 agtatgtcga actttagcga tagaacgacg tgattctttt tcgttgtaaa acatcaaaat
    10081 cacatataga gagtccaaaa tgcttagttg agaaatacgg gaagctaaag cttcagatcg
    10141 gaattctgtt tcttcagaaa tagaaataaa aacgacatcg ccaagtttag caagggaaga
    10201 attagcttgg ctagtaataa cgattgtttt tgctccagtt tttcttacgg tttcagcaat
    10261 atggattgtt tcttttgatt gccctgtgtg agaaatcaaa acagcacagt ctttttccgt
    10321 caataaagaa gcttccatca attgaatatg gtaatccgtg ctgtgagaag ttgcgatagg
    10381 ggaacgcaaa aatttatgat aagcgtcagt tgctacaatc tctgaaccgc caacaccgaa
    10441 aaaatagaca cgtttagatt cattgataat agtagccgct ttttttagat ccttttgttg
    10501 taacaacttt tttgtgtcat ttaaagttga aatactagac tcgaacacct tttgcgccat
    10561 agtgagctca gtatctgttt tctgaatatt ttcgtggata gaaatagcag atagatcatt
    10621 ttcttggatc aacatggcca ttttaaaatc tttaaatcca ttataaccaa gtttttttgt
    10681 aaattgaaaa aaagtagagt cagcaatgcc cagttcactt gctaaattgc taataggact
    10741 atgacttact ttgcttggat tttctaaaat ataatcggcg atagcctgtt cttttgggct
    10801 gaagtcgttg tacattgttt tgatttgtag tcttatggag acgctcatga gaattcctca
    10861 ttttcataat aagattatca ttttttccgt tctcattaat gttaaagata caaggagagt
    10921 aggaaaaaat caaacaaaaa atatttttgt aaaatctatt tacaaaaaaa tttttttgta
    10981 taatgagggt ataagaaatg gaggcgctat catggaaatt ggtgtaattg gtttgggaaa
    11041 aatgggattg aatttagctt taaacttaaa agagcaccat cacaaagtac aaggactcga
    11101 catttcaagt acagctgtta gtcaggcaag agaaaatgac attcctgctt atcaagagat
    11161 ctctgaattt ctagctactt ttgagcagaa aaaaatcatc tggttaatgc ttcctgctgg
    11221 agagataacc gaaaacatgt taagaaaact ttttccaaaa ctcggaccag gagacattat
    11281 tattgaaggc ggaaactctt attataaaga ttcaatccgt cgagcagaag agtttcagaa
    11341 aaatgaaatc ggttacttgg attgtgggac ttctggagga atcgaaggag cacgacatca
    11401 agcctgctta atgattggag gagataaaga aacttttcta tccgtggaac aattattcaa
    11461 agatgtagca attgaaagag gatatctgta tgctggtgca tccggaagcg gacacttctt
    11521 gaaaatgatc cataatggaa tcgaatatgg aatgatgcaa gcaatcggtg aaggattcca
    11581 acttgtacaa aaaagtgagt atgcttttga cttggaacaa gtcgcacgtg tttggaatca
    11641 tggttcggtg attcgcggct ggctgatgga aatcatggaa gatcagttaa acgaacatcc
    11701 caatttaagt aattatcggg gaatcgtttc tgcatcaggt gaagcaaaat ggacggttga
    11761 aacagcgcta gaaatggctg ttccagttcc agtaattgca actagtttgt tcatgaggaa
    11821 tctttcacag gaagaagata gtttttcagc aaaagtagtt tcagcactaa gaaatgggtt
    11881 tggcggacat gaaatagttg aaaagggtga gtaaaatgcc agattatcat atagcaatcg
    11941 ttaattccag cagtttcgga agagtctttc cacaccactt ggaaagatta aagtcagttg
    12001 gagacgttca tttctttaat gttgatcaag agattccagg aaaagaacta gcggagttac
    12061 ttaaaggatt caatatcatt attgcaagtg ttacgccatt ttttcgacga gatttttttg
    12121 aaaacaaaga tgaactgcta ttgatttccc gacatggtat tggttacaac aatattgatt
    12181 taaaagcagc aaaagaacac cagacaatcg tatctatcat acctgcttta gttgaacgaa
    12241 atgctgtagc agaaaataat ataactaatt tgttgtccat gcttcgacgc acgacacaag
    12301 cacaagcaag agtcaaggac gatcgatggg aagatcgggc ggagttcgtc ggtaggacgc
    12361 tgtttaacaa aacagttggt gtgattggtg caggaaatac cggaagcgga gtaatcgaaa
    12421 ttttgcgtaa cggttttcgc tgtgatgttc tagcttatga tccttacaaa tcagatttat
    12481 acatcgaaag ctttggtgca aaaaaagtag aacttcaaga attactggaa caatcagata
    12541 tcatttgttt atgtgcgaat ttgacagaag agaactatca catgatttct gataaagaag
    12601 tcgatcagat gaaagaaaat gtttatctat ctaatagtgc aagaggcgct ctagttgatg
    12661 aagaagcgat gattaatggt ctgaaaagcg gaaagatcgc aggatatgcc acagatgttt
    12721 tagaagaaga accgggacgt caagatcatc cgtatttagc gtttgaacaa gtagtgatta
    12781 cgccacatat atcggcctac acaagggaat gtttagaagc aatgtgtgaa aaatgtgtca
    12841 gagatgtcga acagatcagt cagcaccttc ttcctgaacg ttctgtccag acaaagagca
    12901 actatataaa aggatgatga agaaaatggt gaacggttta aaagtgaaaa caggccctca
    12961 attttattta tatgaagaag gtggtatttc aaaagtttct gatctcttga aatcatacgg
    13021 cgcgaaaaga gtactggtca cccacggaac ggtatcatgg gaaaaggcgc tacctaaatt
    13081 agtatttttg aatgacgaaa cgattcaatt tttttatcat cgttattctg gagaatgtag
    13141 ttatgctgaa gccagacgaa tagctacaat catcaaaaaa atgaaatcga tttcgtagtt
    13201 ggcgttggcg gaggaaaact gaccgatcta gtgggttata gtgccaatct tgcaagaatc
    13261 gatttcggag tcatccctac tttagctagt aattgtgctc catggacacc tcttgctgtc
    13321 atgtataagg agaatggaca agcagaaggg aaaacagaac acttttacag acaagctgct
    13381 ttttttataa cagatcccca attagtgatt gattcccctg ttccatattt cattgccggg
    13441 ttagcagata cactagcaaa atggtatgaa tctgagctca tcttagaaca agattttttg
    13501 caagatgaat catttttgaa gctagcacaa gatactgcga agatctgcaa agaagagatt
    13561 ttgaatcatt ctgctaaagc aatccaagat atggcacaaa gaaaactgtc atcggagttc
    13621 aaacagcttt cagagattat ctttgctgtt gctggtttag ttggaggatt aggagataaa
    13681 tacgcaagaa atgtggcagc acatgctatg catgacgcta tcagtaaata tattccggaa
    13741 agccatcgtt ttctacatgg agaaaaagta gcgtatggga ttttctatca actggcacta
    13801 gaaggtcgct gggaaaaaat agacgagtta tatcctttgt atcgggaatt agaactgccg
    13861 gtttctctag aacaaatggg attatttccg aaagataaac agataataga taaaatggct
    13921 gaatttattg attcgaaaga gaaagtgcat ttgattccta tagaggtaac acagaaatca
    13981 ctgatacagt caatgatgga actggaaggt tatatcagaa agatctgaag gaggaggaca
    14041 catggaaaca ttaagtgtag tacaaagttt gttgattgct ttatgggtag ccgcggttat
    14101 gtcccgctgg ttaggtggag gagccacgtt gaccttacgt ttttctcctt tgatgactgg
    14161 attagtcgtc gggttgatca tgggggaagt tgcacaagcg atgattgtta cagccgcttt
    14221 gcaaatgatt tatatggggg ttttttctcc aggaggatca atgccagctg aaccatctat
    14281 tgcagcagct atcgcagtac cagtcgcatt attaggggat ctgtcgccag aagcagcgat
    14341 tgccgttgcg gtgccagtcg gattgctcgg aagttacttg tatcagtttc gttttttcat
    14401 caatactttt ttaggtaaat atacagacaa agctgtagaa gatttgaata caaaagctat
    14461 ggcccgatca attattcttt atccaacggt tgcctcattt ttattattcg ttccgcttgt
    14521 tttcattgct ttatatttag gggcgccatt gatcgctgat gtaatcaaag ctttagaggg
    14581 aacagtcgtt atccacattc ttgaagtagt aggtggaggg ttagcggcaa tcggtatcgc
    14641 gacaactgta tacgttatcg gtcgaaaaga ttatctggtc tttttcttcc ttgcttattt
    14701 tatgagtgtt gttttgaaat ctttagatat tacgatggtt acttatgcca tttttgggat
    14761 tattatcgct ttgatctttg tccagtcgca aaaagggaaa caagtacagc ctgccacaag
    14821 caataacaat tcagcatctt ttgatgacga agatgactat gatgacggat tttaatttag
    14881 gaggaatggg aaatggctga aataatggat aatcaaacag gtgctcctga agaaatcacg
    14941 aaaaaagatg taacaaaagc ctatctgaga tggcattttg caaacgaaat tcctcactct
    15001 tttgaacgtt acttggcgcc atcactacta tacggaatga tgccaatctt gaaaaaactt
    15061 tataaagatg aagactcttt aaaagcagca tataaacggc agttactgtt cttcaacact
    15121 caattaagct ggggtggcgg tgtgattact ggcctaatgt cttctatgga acagcaaaga
    15181 gcagaagaag agtatgaaga aaaagagatc ttgatgcagg atgacttgat gtataacacg
    15241 aaagcgggat tgatgggggc actagcagga atcggagatg caatcgattc aggaaccgtc
    15301 caatatattt ttatcgcaat cgcggtacct tgggcacaac agggaagtcc tttaggcgca
    15361 ctttttcctt ttatctgctt tgggttgtat caggttttac taggggtatt tttcgcaaga
    15421 caagctttca ctatgggccg taatgctaca ggcctaaagc aaaacactgg tgttcagaca
    15481 gcgattgaaa tgctatcagt tttagggttg tttatgatgg gggtgcttgc gggaaactat
    15541 gtaaaagtag aatcttcatt gaaatttgcg atatccggac gtgagtttgt tatccaggaa
    15601 attcttgatc aaatcgtgcc agggatatta cctttagctg tcgtaatggg tgtgtacttg
    15661 ttctatacga aaaaaggatt gaaagtcaca caagcattat tatggctgac tggaatatta
    15721 attgtgctag caggaatcgg tattttataa aaagaaggga acgtgaataa gatgggtgta
    15781 gtcaatttag cgcgtgtgga tgagcgtttg atccatgggc aagtaatggt aacgttatct
    15841 caaaaaagtg gagtgaattc catttttgtt gtagacgaag ttgtagcaaa agataaattt
    15901 atgagagatc tttacaaaaa tgcaggaagc cgtacaggac aaaaaacaat tgtcattaca
    15961 ccagagaaag ctaaattcta ttgggatgaa tatcaattta aagaatacaa ttgtattttg
    16021 atcgcaaaaa cagtccaaac gatttacgac ttagtaaaac acggaatccc catggaagaa
    16081 ttgaatattg gagggattgc tcaaaaaaat cctgatacag atcttttagt gacgaaatct
    16141 gtttatttaa ataaatcaga tgctgaaaaa ttgaaagaaa tgaatgaaca atatggcgta
    16201 aagaatattt attttcaagc cactccatct gcacctaaaa caggattaaa agatgtattg
    16261 aacaagtttg atttgtcata aacaaatgct tagaaaaaag ataaagaggg cgaaaaaatg
    16321 aagaagaacg agctgtttcg tgattgggaa tttcgttatc gctatattta ccgtaagcgc
    16381 cgtacaaaaa agagtaaaca gcgttttctt tcagcattag tatcagatat ttacagtatg
    16441 agaacagatg tgacagtcat tgcttacgat acgctagcct accgatcaaa aaatatttat
    16501 gttggagata tcgaaaaagc agagaaagtt atctgtactt attacgatac acccgttcat
    16561 gcattaggaa gttatttcat gtttgattgg aaagaccaaa ggaaaaaaac aatctactct
    16621 atattattgt ccttcatttt gttgttcagt ttaggttggt ggggaatgat gatatataac
    16681 aaaaatcctc atcacgtatt cgatctgcta tccgtataaa caggtatcac tgtactagca
    16741 tttgggagct actttttctt attgggaaaa gcagctcgcg gatggcctag cagacaaact
    16801 tttattcgaa atacttcatc catattaacg atgctagaaa tgatccgtac gattgatgat
    16861 ccgagtgtag cgtatgcgtt tgttgatgaa ggctgttatg gagaaaaggg cttagacagc
    16921 gtgagatcgg gtatgaaaaa agaggctatt cttttttatc tagactctgt tggggcagat
    16981 acaccgctac agttttcggg aaattatttt tcaaataaag aacagtggct gaaacaagtt
    17041 gataagttga aagaaaaaaa cgtcaattat atttttagtg caagaaaaaa gcaagcgcag
    17101 ttcttctatt tgaccaaaac agatttacga gggaaaacat ttaattggca aaatgccaat
    17161 cagattattg ctctttttcg ataagtaaaa agtgcaaaac aaggagtgag aagactaatg
    17221 ttggaaatca tgatcgttac acatggtaag ttgagcgaag gactgaaaga tgcggcggaa
    17281 gtaattgtcg ggacatcgag ccatattgaa acaatgtgct tagagtctgg ggaggacatc
    17341 caaacattcg gagagaaggt caaagaaaaa ttaactatga tcaacacagc agaacccatg
    17401 ctagtatttg ttgatctaat tagcgcaagt ccgtacaatc aagcgctctt ggcagtcaat
    17461 gaactgactg aagaaaagaa agcagccact tatgtcatag ggggcgtgaa tctgccaatg
    17521 ttgttagaag caatcaatca tcagatgctt cacacaccga tagaagaagc ggtggaacaa
    17581 attgtcaaac aaggaaaaga taatttaact gtttggcatg cttcagcgga agaaaaaaaa
    17641 ttagatgagg acgattttta gaaggaaggc tgaaaagatg aagtggggat ttagatggta
    17701 tggtgaaaaa ggggattcga tcccattaaa atatgttcgc caaataccgg gaataaatgg
    17761 gataattgga actttgctga ctaaaatgcc tggagatgtt tgggagattt cagaaattga
    17821 ggagttgaaa gcatctgttg agagccaagg actggaactg cttggaattg aaagtgtagc
    17881 gatccacgat gcaatcaagg cagggacaga tgaacgagat tactatattg ataactatat
    17941 acgaacaatc aaaaacttgt ctcgatgtgg ggttcgattg atttgttata gcttcaaacc
    18001 aatttttgga tgggcgaaaa ctgatttgtt taatgaaaac aacgatggaa gctattctct
    18061 tttatacgat cagaaaatcg tcgatcagat ggagccagga gaaatgtatc aattgataca
    18121 cagccagtca aagggattca aattgccggg ttgggaagaa gaacggttga aaaaattcgc
    18181 tcagctggaa aaactgtatg aaggaatgac cgaagaagaa ttatttgaaa atctgactta
    18241 ttttttagaa aaagtgattc cagtgtgcga aaaagcagat gtaaaaatgg ctatccatcc
    18301 agatgatccg ccatgggaac tttttggttt tcctagagtg acgaaaaatc ttggcgactt
    18361 gaagaaaatt ctaaatgcag tagattctcc atataatgga ctaacgctgt gcacaggatc
    18421 tttaggggca aatccggaaa acgatttagt tgaaatcatc catgaggtag gttcgcgcat
    18481 ccattttgtc cacttcagaa acgtggagtt tttaggagaa agaaagttca aagaaacggc
    18541 acatccctct acagaaggct cccttgatat gtatcatatt atgaaagcgt tggtgcaaga
    18601 agggttcgac ggtcctatac gccctgatca tggtagaacc gtgtggggtg aagtggctat
    18661 gcctggatat ggcctgtatg atcgtgcaat gggactcact tacatgcaag gtctatatga
    18721 ggcgataagt aaggaaaaac cactgggaga gcattatgaa taaaatcaag ctcttcatct
    18781 ttgatatgga tggcctttta ttagaaactg gacgtttagc ttatcgtgct tatgtaaaat
    18841 cagcacaaaa gtatgattat gaaatgcgta aggaagtcta ttatttacta actggccaaa
    18901 cagaaatggc gataagagaa caaatgggca ttttgtacgg agaagatgtt ccatatatca
    18961 aatggcgaga agcaatcaat caatataaag aaaaaatcgt gaaagaagat aagagagtat
    19021 atacgaaaaa aggagcagaa gaaattttat cttttgcaaa agaaagagga atccatacaa
    19081 tcgtggcttc gtctaataca cgggtaaaag tagaaatgta tttaaaaatg gaaaatctat
    19141 atgccttgtt tgatcaaatc atttcagggg atgatgtaaa aaaaggaaag ccggaaccag
    19201 agatcttttt gaaagcttgt tcaaaaatga atattcctcc aagtgaagca cttgtatttg
    19261 aagactcgat tgcagggatc gaagcagcaa ggcgagcggg cattttgtct tttctcatca
    19321 aagatcattt gatagggttg cccgatcata atgggaagca taagttgaaa gtagatgtaa
    19381 gtttatatga atccaataaa gcagactatg aattttatga cctgcatcaa gcaaaacgat
    19441 ttttagaaag taaagggttg tatctctaat aaagaggact attttctagt cctctttatt
    19501 tattgtcctg cacgactgag ggaacagatg aaaaagaagt aattttttat tttgaagtat
    19561 ctaccttatt tgtagtgaac aatttagaac aaacacaaaa cgcatctact gtt
//
LOCUS       DACBYO010000050        19507 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.050, whole genome shotgun sequence.
ACCESSION   DACBYO010000050 DACBYO010000000
VERSION     DACBYO010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.050"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="IVD26_001752"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="IVD26_001752"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAP6079701.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="IVD26_001753"
     CDS             complement(1173..1868)
                     /locus_tag="IVD26_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAP6079702.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="IVD26_001754"
     CDS             complement(1881..2597)
                     /locus_tag="IVD26_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAP6079703.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="IVD26_001755"
     CDS             2927..3532
                     /locus_tag="IVD26_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAP6079704.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="IVD26_001756"
     CDS             3857..4180
                     /locus_tag="IVD26_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAP6079705.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="IVD26_001757"
     CDS             4362..5732
                     /locus_tag="IVD26_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAP6079706.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="IVD26_001758"
     CDS             complement(5862..7163)
                     /locus_tag="IVD26_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP6079707.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9384)
                     /locus_tag="IVD26_001759"
     CDS             complement(7393..9384)
                     /locus_tag="IVD26_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAP6079708.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="IVD26_001760"
     CDS             complement(9528..9794)
                     /locus_tag="IVD26_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP6079709.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="IVD26_001761"
     CDS             complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="IVD26_001761"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAP6079710.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="IVD26_001762"
     CDS             complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="IVD26_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAP6079711.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13138..13701
                     /locus_tag="IVD26_001763"
     CDS             13138..13701
                     /locus_tag="IVD26_001763"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP6079712.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13954..14475)
                     /locus_tag="IVD26_001764"
     CDS             complement(13954..14475)
                     /locus_tag="IVD26_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAP6079713.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14478..15320)
                     /locus_tag="IVD26_001765"
     CDS             complement(14478..15320)
                     /locus_tag="IVD26_001765"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAP6079714.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15313..16038)
                     /locus_tag="IVD26_001766"
     CDS             complement(15313..16038)
                     /locus_tag="IVD26_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAP6079715.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16214..16510
                     /locus_tag="IVD26_001767"
     CDS             16214..16510
                     /locus_tag="IVD26_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079716.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17078..18670
                     /locus_tag="IVD26_001768"
     CDS             17078..18670
                     /locus_tag="IVD26_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP6079717.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18683..19423
                     /locus_tag="IVD26_001769"
     CDS             18683..19423
                     /locus_tag="IVD26_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP6079718.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5580 a         4002 c         3702 g         6223 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt catcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc
    10261 tgtcaccttc acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt
    10321 tcgttgaacc atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat
    10381 cgatttcagt tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat
    10441 tgacacgatc gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt
    10501 tgacgaatgc accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt
    10561 tgacttcttt ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag
    10621 ctgaagcaat acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga
    10681 tgattccgtt gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga
    10741 tctggatcat ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg
    10801 ttgaagtcaa ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag
    10861 ttaggatttg ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat
    10921 cttttgtacc ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat
    10981 cagttaggat cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg
    11041 gcgctttgat tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt
    11101 gggaagaaga accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt
    11161 cttcttctga agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt
    11221 cccgacgccc tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt
    11281 agtggtggat gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc
    11341 ctagaggtgc gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg
    11401 atccatgtac acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt
    11461 tacgcccgtc aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa
    11521 gatcttctgt gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa
    11581 atttctcagc ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag
    11641 caagtttttc ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt
    11701 cttttttcaa tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg
    11761 cttgaacgat ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca
    11821 atgcaccaag catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg
    11881 cttgtttcgt tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg
    11941 gattcaagac gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa
    12001 atgggatatc tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg
    12061 agcagtctgt ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt
    12121 ctgcaaacat cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac
    12181 ttggacggcc ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt
    12241 cttcataatt gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag
    12301 ctgcacttaa gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg
    12361 ctagctgacc gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt
    12421 tttctgacat aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa
    12481 aactgccgaa agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt
    12541 gatcacggaa ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc
    12601 actctttttg actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt
    12661 tgaacgtcag ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt
    12721 aggccgcggt atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg
    12781 atttcttcag ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga
    12841 gcgtattcgt tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct
    12901 ttcgattatt cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt
    12961 catgtgccta gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta
    13021 atcattaaga aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa
    13081 actataatgc gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg
    13141 attacaatgg atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa
    13201 gtttctcttc cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta
    13261 aaaaacagcc aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta
    13321 gctgctcctc aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac
    13381 ccagaggcag atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat
    13441 tctgttcaag atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta
    13501 ccaggatatg ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa
    13561 aaacacaaga ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat
    13621 atcaacggtg tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa
    13681 ggcgtattgg tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag
    13741 ctttataaaa aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa
    13801 tcgaaattta gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg
    13861 catcttttct tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa
    13921 tagtttctag gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc
    13981 agctagtttt tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag
    14041 atggatgccg cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat
    14101 aaaggaatcg atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag
    14161 gggatgttcc acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc
    14221 ttcttctgtt tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt
    14281 ttcttctgtt tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg
    14341 tagtaaagca atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt
    14401 gctagcactc actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt
    14461 ctctccttcg atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc
    14521 atcaaatcaa catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta
    14581 acaactttat ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct
    14641 tttttcactt gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac
    14701 tctcgatcga tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct
    14761 tcctctactg tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa
    14821 gatttggtca caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc
    14881 gtgacgataa ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac
    14941 tccagaccgc tgttacgttt cactggatgt agtggatgcg tcgccgtgta aagctggaca
    15001 ttcggagcga acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa
    15061 ttgaaatttg cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata
    15121 actggctcca tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat
    15181 cgcagttccg ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg
    15241 tcggcaacca gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt
    15301 tcggttttga attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc
    15361 tccgtcttct tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac
    15421 taagattttg gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa
    15481 actcgttcca acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat
    15541 gactccatct tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca
    15601 tgcttgatgt ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg
    15661 acaatgacat tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc
    15721 gtgcaaaccg tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc
    15781 tatttccaaa tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg
    15841 atagaattta tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc
    15901 catcccgtgg tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac
    15961 ccctgcaccg gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc
    16021 tactgttaat tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa
    16081 atttattgtt gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat
    16141 ttatcacaat gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt
    16201 gaggtgaatc gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc
    16261 ctggttagcg ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa
    16321 tctttgggct tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc
    16381 cgtatatcga acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt
    16441 agccatttat ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc
    16501 ggcagcttaa atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt
    16561 ttattgtatt acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat
    16621 tcacattttg attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc
    16681 aaaaaccagc agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa
    16741 ataactgaat acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg
    16801 tggagtgaag caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt
    16861 tgcttggagt gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc
    16921 taagttgcgc tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta
    16981 tatctataaa tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga
    17041 ccgctcgtgt atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt
    17101 tgccgtacta tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga
    17161 tgaaaaaaca ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa
    17221 ctggtctcaa caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc
    17281 cggcggttat gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt
    17341 catcgtccaa acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc
    17401 gatcatcgcc ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc
    17461 ttattacgaa tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa
    17521 aagtttagca gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac
    17581 tgtgatcgat cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat
    17641 gagaacagct ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt
    17701 aacggcaact agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt
    17761 ccagacaaac ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat
    17821 ccaaaaagta aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga
    17881 ccaagcagtc aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc
    17941 tgatttcact acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac
    18001 cttgttcatc gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt
    18061 cttccgttcg gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa
    18121 tgcacttctt tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat
    18181 ggtcatcttc tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc
    18241 tttgtttatt gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat
    18301 ttttgcagta gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca
    18361 aacgatgaga aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa
    18421 tgagtttgtt atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt
    18481 gttcttccaa ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat
    18541 cgtcgggatc atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga
    18601 aaagaaaatc gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt
    18661 gcaggaataa ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa
    18721 aagcttcggt gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt
    18781 tgtgacgatc atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt
    18841 actggaaaaa ccaacaggcg gcgagatcat ttataatgga gaaaatgtat tagctcctaa
    18901 atataattta cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt
    18961 caacaatatg aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga
    19021 taaagaaact gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta
    19081 tatcgaagcc aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg
    19141 ggcattatca atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc
    19201 tgaaatggtt ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat
    19261 gcttatcgtg acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat
    19321 ggataaaggt gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga
    19381 agaacgtaca aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg
    19441 gacaaagagc tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat
    19501 ttctgaa
//
LOCUS       DACBYO010000051        19279 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.051, whole genome shotgun sequence.
ACCESSION   DACBYO010000051 DACBYO010000000
VERSION     DACBYO010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.051"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            129..2918
                     /locus_tag="IVD26_001770"
     CDS             129..2918
                     /locus_tag="IVD26_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP6079719.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            2965..3492
                     /locus_tag="IVD26_001771"
     CDS             2965..3492
                     /locus_tag="IVD26_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP6079720.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            3513..4703
                     /locus_tag="IVD26_001772"
     CDS             3513..4703
                     /locus_tag="IVD26_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP6079721.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            4743..6041
                     /gene="asnS"
                     /locus_tag="IVD26_001773"
     CDS             4743..6041
                     /gene="asnS"
                     /locus_tag="IVD26_001773"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAP6079722.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            7218..7892
                     /locus_tag="IVD26_001774"
     CDS             7218..7892
                     /locus_tag="IVD26_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP6079723.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            7889..8230
                     /locus_tag="IVD26_001775"
     CDS             7889..8230
                     /locus_tag="IVD26_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079724.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            8260..8619
                     /locus_tag="IVD26_001776"
     CDS             8260..8619
                     /locus_tag="IVD26_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAP6079725.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            8822..9001
                     /locus_tag="IVD26_001777"
                     /pseudo
     CDS             8822..9001
                     /locus_tag="IVD26_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308695.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            9143..11224
                     /gene="cadA"
                     /locus_tag="IVD26_001778"
     CDS             9143..11224
                     /gene="cadA"
                     /locus_tag="IVD26_001778"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAP6079726.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            11535..13001
                     /locus_tag="IVD26_001779"
     CDS             11535..13001
                     /locus_tag="IVD26_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6079727.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            13616..14155
                     /locus_tag="IVD26_001780"
     CDS             13616..14155
                     /locus_tag="IVD26_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HAP6079728.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            14229..14669
                     /locus_tag="IVD26_001781"
     CDS             14229..14669
                     /locus_tag="IVD26_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAP6079729.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            14682..14891
                     /gene="copZ"
                     /locus_tag="IVD26_001782"
     CDS             14682..14891
                     /gene="copZ"
                     /locus_tag="IVD26_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAP6079730.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            14891..17077
                     /locus_tag="IVD26_001783"
     CDS             14891..17077
                     /locus_tag="IVD26_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAP6079731.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            17097..19268
                     /gene="copB"
                     /locus_tag="IVD26_001784"
     CDS             17097..19268
                     /gene="copB"
                     /locus_tag="IVD26_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAP6079732.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6431 a         3362 c         4222 g         5264 t
ORIGIN      
        1 taaacgccca gacatttgcg tgtctgggcg tttttgtcta ttttctttaa aaagcgatga
       61 gagtattttt ctgcactttg tagtataatt tcaaaagaac attagaggca ggagaagagg
      121 aagatatttt gaaaccaaga acttatgcag tcgttgatat cgaaacgact gggacgaatc
      181 caaaagaaga tcggatcatc caatttggct gcgtcatgat tgaatcaggt cggatcactt
      241 cacgtttttc gatcgatatt catccagggc ggaagatttc aaaacaaatc cagcatttaa
      301 cagggatcac gaatcaacgc gtccaaaaag cgccttattt cgaagatgtc gcccaaacga
      361 tttacaatct tttggcagac accatatttg tcgcgcataa tatttatttt gattataatt
      421 ttttgaacca tgaactcatg cgatgcggac ttcctagttt gaagatacca ggcatcgata
      481 cagtagaact tgcacaaatt ttcttgccga cggaaccaag ctttcgctta gctgatttgt
      541 cagaaagcct tggatttatt catgagaatc ctcatcaggc agatagtgat gccgaagtga
      601 caggtcaact tcttttgctg atcgaagaac ggatgagaaa attgccaatc atcacgttag
      661 agcagattgc gcgattaagt agacacacag gtatggatac gagtcgtttc atttatcatg
      721 tgattgaaga aatgaaagaa aaaccagagc cacttgatcc ctcattagaa atcgtcgatg
      781 ggctagcttt gcagaaaaaa gaagtggaac tattcacatc cgtccattat ggcgagcgga
      841 catatccaag aaaaaaacaa gcaaaagaaa aaatgtttgg taaaacactg atgtatcgaa
      901 aagaacagaa cagactgatg aatgcggtct acgaccattt cacaaaagat gaatcaaaag
      961 atttgatgat cgaagcagct acaggaatgg gtaaaacaat cggttatctg ctgccattga
     1021 gttatttggc tacacctgaa aaacccgctg tcatcagtac cgtttcgcta gttttgcagc
     1081 agcagatcat agaaaaagac attccattgc tgaatcaatt gctagatcag cccatacaac
     1141 ctgtaattat caaaagctat cgccactata ttgatttgca gcgttttaaa ggcacacttg
     1201 tggaaccgcc agaacaaaaa caatatgctt tgtatcaaat ggcggtctta gtttggctga
     1261 cgcaaacgaa gactggtgat ttggatgaat tacatttaac aaatttgaac cattcattct
     1321 ttgcagatat cgcgcacaga ggtattggat ttttagcaag aaatcagtca ttttacgaac
     1381 aagactttgt tcgtttcttg caaaagaaaa tcaggcaaag taattttttg attgtcaatc
     1441 atgcgttttt agtacaagaa acacagcgaa aagaaccatt gcttccagct agtccatttt
     1501 tgttgatcga tgaagtacat catttgccgg aaatcgctga aaaagtaaat gacaaacgat
     1561 taagtattaa ctatttccat aaacaaatcc agcaattaga agaaccaaat cagctgtttg
     1621 accgaataca aagctattta ccgaaagaac atgaagcctt acgctggtta tcgatttatc
     1681 gagaagaact ttctgcgcta tgcgaagcac agatttgtat ggcagaagga ttaatgagtt
     1741 tagtgagcgg caagcaacct aacggacagt atccagaaga agtcatgatg acaaaagaga
     1801 tgttggatca gctgccactg gaatctggga cagccattga tcacctgcag cttttttatc
     1861 aggagatcca gcagctacag tcacaaatgc gtctgacttt tgagattatc caagaaagct
     1921 ggacaaacca gatgcggatc gatttagcaa gtttatatag cctatttgat caattagaca
     1981 agcaatactt gctgatggat caatggctgg aagactggcg agatcatttg atccattggt
     2041 tcgttcctgg gaacacagcg cagcagatga tttttcatct ccatgatttt caagcggcta
     2101 tgttgccgtc gactgtttgg tatcctcgat atgatcgtat tctttatatt ggaggaacgc
     2161 tgaagatcgg ccctaatcga cactatctct ctaagaggct tggcattgaa gcagcacctc
     2221 ttaaagtgat tgcctctcct tatgattatg agaaacaggc aaggatctat gtgccaaaag
     2281 aggcacctgc cgtccatcaa gtcagcaatc aagcatatat cgattattta gagacagcac
     2341 ttacaggtct gatcgaacaa gaagatcggc caatacttgt gttattcact tctcatgatg
     2401 ttttgcagaa ggtctatcag aaaatgcatc tgtctatgct agaaaaagga cgagaaatac
     2461 tagctcaagg gtttggtgga agccgggaga agcttttgaa acgcttcatt ttgtcagaaa
     2521 aaagcgtatt gtttggcgct gacagctttt gggaaggtgt agatttgcct ggagatgctt
     2581 tgcagatcgt tgtagtcaca cgtttaccct tcgataatcc gcttcgcccg atggtcaaag
     2641 ctaggaacgc ttatttagaa tcagagggga tcaatccttt ttaccaggaa tccgtaccta
     2701 aagcagcttt gaagttacgc caagcattag gtcgcttgat aaggacggag acagatcgtg
     2761 gcgtattgct tattttggat cgaagactag tcactgcaaa atatggcgca cggatcatcc
     2821 atgcattacc gaaaaaagta ccgatcaaag agctagctat ggaggaaatc tatcaggata
     2881 tccatgaatt cttaaagaaa aatgaagaag gaagttagag gagctgtctt ttttcataat
     2941 taaaatctgc tataatgaaa aggaatgaag ataaaggagc gacgaccctt gaagaaaaaa
     3001 cagacaaagg aaaaaacgat taatcgcgtg ttacttggct tgatcgtatt tttattagcg
     3061 gtcatcgtga tcagctcgat tttttacttg cgttccagtc gtccggcggt gcaggcgaag
     3121 aaagaagcag tagaaatcgc aaagaaatat gcaaatcttg aggaaaccga tcatttttat
     3181 tggtttactc gaaagaagac atacttttca ctgacaggta caaatgataa aggaaaagaa
     3241 atcgccgtta tcattcctaa atctggtgaa aaagtaaaag tattggatca aacaaaggga
     3301 ctgactgaaa acgaagcaaa acagacaatt gctgcggccc atcctgaaat ccaaatcgaa
     3361 aaagctgctt tagggatgta tgatgatcag cctgtgtggg aagtagtagg aaaagaaaca
     3421 aatgggaaac tgaattatta cctgattggc tttgaatctg gagatgaagt caagacaatc
     3481 aagggaattt aaaaggtaaa ggaatgaatg ggatggagtt atcaaaaaga acaaaacgat
     3541 tagaaccgtc tgtcactttg gcagctgcgg caaaggccaa ggcattaaaa gcaaaaggca
     3601 gagatgtgct gagtttgact gtgggagaac cggattttgc gacaccagaa aacatccaag
     3661 aagcagcaat cgaagcaatc cgcaatggga aagctagcta ttatacacca acagcaggaa
     3721 tcccagagct tcgacaggca atcgttgatt atctgaagaa aaactatgga cttgtctatg
     3781 aaccttcaca aacagtcgta acagacggag cgaaatttgc tttgtatacc cttttccaaa
     3841 cgatccttga cccgcaagat gaagtcatca ttcctgtgcc ttactgggtc agttacggtg
     3901 agcaagtaaa actggcagaa ggacttcctg tctttgtgaa aggggaagaa tccaatagct
     3961 ggaaagttac tgttgaacag ctagaacaag cacgttcaga aaaaacaaaa gccgtaatca
     4021 tcaattctcc atcgaatccg actggaatga tttatagcaa gaatgaactg caggcaatcg
     4081 gtgaatgggc agtaaaaaat gatattttga tagttgctga tgatatttat ggccgtttag
     4141 tttataatgg caatgagttt actccaattg caacgatttc agaagcaatc aaaaatcaga
     4201 ccatcatcat caacggcgtg tctaaaacat atgcgatgac aggctggcgc attggttatg
     4261 cggtgggaaa tcctgtgatc atcaatggaa tgatcgctgt tgcttcccaa tcaactagca
     4321 atccgacagc agtcagtcaa tatgcagctg ttgaagcatt gaaaggtgag caagatacag
     4381 tagaagaaat gcggaacgcc tttgaagaac gcctgaatac gttatatccg cttgtggcag
     4441 aactgccggg tgtttctctt gaaaagccgc aaggagcttt ctatcttttt cctaatgtaa
     4501 aagaaacgct acgcatgtgt aagtatgaaa atgtcacaca atgggtagaa gatcttttag
     4561 aagaaacagg ggtagcgctt gtgactggcg aaggctttgg ggcaccagaa aatgtccgca
     4621 tgagttatgc cactgatcgc gctacgttag aagaagcggt acgcagaatc aagcaattta
     4681 ttgagagtaa aagtcaaaat taatcctgaa gaaattcaag gaatataaaa ggagagtcat
     4741 acgtggaaca aattcaaatc atcgattcga aaaaccatgt gggagaaaca gtaacaatcg
     4801 gcgcttgggt cgcaaataag cgatcaagcg gaaaaatcgc atttttacaa ttaagagacg
     4861 gaacagcctt tttccaaggt gtagttgtaa aaagcgaagt gccggaagaa gttttccaaa
     4921 cagctaaaaa tctgcaccaa gaaacatccg tgttagtaac tggagaaatc cgtgaagaca
     4981 gccgttcaaa atttggttat gaaatcggaa ttacaaatgt ggaagtggta agcgagagcc
     5041 acgattatcc gatcacacca aaagaacacg gaacagactt cttgatggat catcgtcatt
     5101 tatggctacg ttcttcaaga caacatgcga ttatgcagat cagaaatgaa atcattcgtg
     5161 caacgtatga attctttaat caacatcatt ttgtcaaaat cgatccgccg atcttgactg
     5221 gttccgcacc agaaggcact acggatctat tcgaaacaaa ttactttgat caaaaagctt
     5281 atttatctca aagtggccaa ttatacatgg aagctgctgc tatggctttc ggaaaagtct
     5341 tttcattcgg tccgactttc cgtgctgaaa aatcaaaaac acgacgtcat ttgattgaat
     5401 tctggatgat cgaaccagaa atggctttca ctcatcaaga agaaagttta gaagtacagg
     5461 aacaatatgt agcattctta gtacaaaatg ttttagatca ttgcgaatac gcattagatg
     5521 tactaggacg agacaaagaa gtcttaaaaa cttatacaaa attgccattc cctcgtatta
     5581 cttatgatga tgcgatcgaa ttactgaaga aaaatggatt tgatgacatc gaatggggcg
     5641 aagactttgg ttcacctcat gaaacgttca ttgcgaattc attcgaacag cctgtcttta
     5701 tcctaaacta tccaaaagct atcaagccat tctacatgaa accacatcca acaagagaag
     5761 acgtggtaat ttgtgcagat atgatcgcac cagaaggtta cggtgaaatt attggcggaa
     5821 gcgaacgggc aacggactat gatttcttgc tagaacaaat ccgtaatcac ggtttggatg
     5881 aaaaagaata ttcatggtat cttgatctac gtaaatacgg ttctgttccg cactctggtt
     5941 ttggtctagg ccttgaacga acagtcactt ggattgctgg tatcgaccat gtgcgtgaag
     6001 ctattccatt cccacgtttg ttgaaccgaa tttatccata agaggtgatg aaaaagctgt
     6061 tctgcatcaa gtaattagaa cagccaagca aaaacagctg ttcatgtttt tgaattggcg
     6121 ggacttatta ccgcagatgt aagcttttga ataccgttta gtggagaggt tgtgaaaaag
     6181 ctgtttagtt tcgagtatta agaaaaattt tgtggaaatg gctttccaca tttttgcata
     6241 aatttggctt aataccgaga aactggcttt tgaacaccgt ttaaggaaga ggttgtgaaa
     6301 tcagtgcctt gacctgagta ttagagaaac aaaacggaaa aatagcttct catattttac
     6361 cgttttttta gctaatatcg agggtcagct gattgaacac cgtttatatc aagaggttgt
     6421 gcgcctgccg ttcagctccg agtcacaagg agtaatttca aaaaacagtt tttcatgttt
     6481 gatgactatt gtgacttgtg accgaggagt tggccggaga gcaccgttta ttctaaaaaa
     6541 gaactgcgaa ctctcgcagt tcttttttta aaatacggga taaaggaagt ttccagcaga
     6601 caagagaaga aagcaaaaga aattgctatt tgattcacaa ggttctataa cgaaatcgca
     6661 atcaatcaaa catttacaaa gaaggtaatt caaatggaaa tctgatttga tgatgcttct
     6721 gctgttgaaa taaagcagca tctagcacct gaaaacaaac taatagtaac attcgaagat
     6781 ggagtaggtc cgtattttca gcatgcaata atccatatgt aagttcaatt cacccttgaa
     6841 atcatcggac cagataaagt tatgaccaat ctatcccaag caatctagaa gagatattag
     6901 taaagggaca tttactagaa gtcttagatg agcctataaa tatatgttct gatggcgtca
     6961 tcagtggtct gattgacgga agcttaggtg tgatcgatct ctctggacca aacaacgaag
     7021 gaatcaaggg gaatccggca cgttaagaaa aaaatagcat aaaaaactag acacttgatg
     7081 agcgttcatt caattgtttg aagggactag gctggtgtca ttttttatac atatattttc
     7141 tctttcgtct tgatagggct tatgggataa tataaggaag aaaatcatcg ttttattcaa
     7201 aaaggagttt ttgacaaatg aaaaaacgta tattatttat cggtgatagc attacagacg
     7261 caggaagaga ccgagcagaa gcaactgatc taggtaaagg ttatccactt ttgattgccg
     7321 gaaaactaat ctcccaatat ccaacgatgg aatttgaatg catgaaccgt gggataggag
     7381 gagacaaaat tgcagatctg caagtacgct ggcaagaaga ttgtttagct ttacaacctg
     7441 actatgtatc gattttgatc ggaatcaatg atacctggca taatactagc gatcaggcta
     7501 tattcggaac tgagaaatct gctcagcaat ttgaatccgt ttatcgaaaa ttactaaatg
     7561 aacttcaaac agtgggaatc tgcaacatca tcttgatgga gccgtttgta cttcctataa
     7621 ccgacgaccg tcatggctgg cgtaaagact tagaccctaa aatccaaatt gttcgtaaac
     7681 ttgctaagga atatggcgca ttgctggttc ctttagatgg tatattcaat gctttaggga
     7741 ttgtttatgg tttttcgaaa tatacaagag aagatggggt ccacccaacg attggcggac
     7801 atgagatcat tgcacaaagc tggatagatg caattgccgc agtcgatttt tttagtggag
     7861 ataaaaatga gcgaaagaaa agtgagaaat gatggaaata cggtgggcag taaaagaaga
     7921 tctacctcaa atcaatcagc tgattactga tcatccagaa tcattcgtaa aagcaaaaac
     7981 ggcagctgac ctaaatgata agaataaact attgctcgtt gctgtaacaa aagaaaaacg
     8041 gattatcgga tttgcgcaag cggacgtgca acagtcagaa gaacgattgg atcagcgacc
     8101 atcaggaaaa ctaatccaac acacattagt aacaaaagaa aatacggaag aaatccaaaa
     8161 aaaatttgca gaatatttga tactggaagc taaaaaaaga agaataaaat cattttttgc
     8221 ccagttttaa tcaaaaacag taatagaagg agaaatacaa tgagttgttt aggaaatgtc
     8281 atctggttta tattcggcgg actaatcggt ggtcttagct ggttagcagc ggggatactt
     8341 tggtgtatca cgatcatagg tatcccaatc ggtatgcaat gttttaagat cgcctccctt
     8401 tcttttgcgc cttttggcaa agaagtaatt tatcaccagt ctggcatgtc attgattgtt
     8461 aatatcatct ggctgatcgt ttcaggccta ccaattgctc tcgcacatgt cgtcagcggc
     8521 atccttctat gtatcacgat catagggata ccttttgcca agcaatcttt caaacttgct
     8581 cgattggcgt tgatgccatt cggtgcagaa attgtataaa agagaataat aaaggttaga
     8641 taaagcatag agtcaggtgg gatacatgta tttcacctga ctctatgcgt tctcctgtat
     8701 aagttcttcc atgtgacttt tacgtctttt atttatatgg ggttactgtt tatggaaagt
     8761 tgaaataatt ttcattaaag aactctttct atatttttga aagcgtagtg gagcttcgaa
     8821 tatctgggaa ggacattttg cagggattga aaaaagatat tgtcctatcg aaaaattaat
     8881 gaatttagac aaattgccag caacaggctt caaacttagt tgctatcctg tcaagatcaa
     8941 gaaggcaagt gcgggttgga taagagcagt ggcaatgatc gaaaagaaaa agaaagaata
     9001 agccaaaaca tctgtatgga agaaattttc cgatgcagat gtttttcatt ttttctttcg
     9061 gataccttga catatgaata accgttcatt tataattagt tatgaagaga tattcatatg
     9121 ttgaggcgag gaggtcatta aaatgaaaag ttacagatta gaaggtttag attgtgcgaa
     9181 ctgtgcaatg aaaatcgaaa aaggagttca gaagatcaat ggagtcaagg aagcaacggt
     9241 aaacttcact tctggaaaac taacgattga cgcagaggaa gatcatttgg ctacgattga
     9301 acaagaaata aaaaaagtag tgaaggaatt agaaccagat gtcaaagtaa cagaaataga
     9361 taaggaaaaa gtatctgaac atggaaatga aaaagagaga aatacgctgt tccggatttt
     9421 attttccctt gcaggtatcg ctttattgct attatttgat tttaatgaac caattcgctt
     9481 gatagggtat ttattgattt atctgctgat aggatatgat gtagtgaaga aggcagtgat
     9541 gaatatcgtc aaaggaaaaa tctttgatga gaattttctt atgtctgttg ctacgattgg
     9601 cgctatgttg atcggtgaat atccagaagc cgtagcagtg atgctatttt atcaaatcgg
     9661 cgagtatttc caaggattgg cagtcagtca ttcaagaaaa tcgattcgcg aattgatggc
     9721 gatccgtcca gaaacagctc acgtgcagac gacggaagga ttgatgaccg tgaaccctga
     9781 agacgtgcag atcggtcagt ttgtacttgt gaagcctggt gaacgtgtac cgttagatgg
     9841 aacgatcatc gaaggagaat cattagtcga tacgtcagca cttacaggag aatcagtccc
     9901 taaatctgta tatgttggtg aaacagtatt aagtggattt atcaataaaa ataaaccatt
     9961 tttagttcaa gtagaaaaat cttatgaaaa ttctactatc agcaaattat tagaattagt
    10021 agaaaatgcc agcagtaaaa aagcaccagc tgaaaatttc attactaaat tcgcgcgcta
    10081 ttacacacca gtcgttgtag gattggccgt tttattagct gttttacctc cacttgttgt
    10141 ttctggagcg gcgttttctg aatggatcta tcgagcattg acatttttag tgatctcatg
    10201 tccatgtgca ttagtgatct ccgtacccct tagtttcttt ggcggtatcg gaggagcaag
    10261 taaaatcggt gtattagtaa aaggttcaaa ttacttggag ttgcttgcac aaactgagac
    10321 agtggtattc gataaaaccg gcacattaac gaaaggtgac ttttcgatcc agacgatcga
    10381 tacaaaaatc gatccaaaga tattcatgca atatgttgcg agtgcagaac agttttctac
    10441 acatccgatt gctcaatctg ttttagaagg ctacgcaggt ccgcttttac caacagctaa
    10501 tatccaagaa tttgcaggtg aagggatctt agctgaagtt gatggcaaac aagtattagc
    10561 aggtaatcac aaattgatgg aaagatttga aatctctttt ccttcaagtc aagaaatcgg
    10621 tacattgctt tatctagcga tcgatcaaag ttacagtggt tatcttgtta ttgcagatac
    10681 cttgaaagaa gatgccgtag acgcattggt tcaattaaaa aaggctggtg tgaagaacac
    10741 agtcatgttg acgggcgatt cgaaaaaaat tgctgatcat atcgggaagc aagtaggcgt
    10801 ggacaagata tatagcgaat tgcttccaga agataaagtg cagcggttag aggaaatctt
    10861 acaaagaaac aataaaaaga ccgcatttgt cggagatgga atcaacgatg caccggtgct
    10921 agcaagagca gatgtaggaa tcgcaatggg tggattggga agcgatgctg caattgaagc
    10981 agcagatgta gtcatcatga atgatcaacc atcgaagatt gcagaagcaa tccatttagc
    11041 aaagaaaaca ttgaaaatcg tcaaacagaa cattgtcttt gctattggga taaaaatttt
    11101 ggtacttgcc ttaggtgctt ttggttttgc atcaatggga gatgcagtat ttgcagatgt
    11161 tggggtgaca gtattagctg ttttgaatgc catgcgaagc ttgcatgtaa aaaataaacg
    11221 ttgatcaatg aagaggacga atgaacgtcc tctttttttt atatcctttt cttaatgaaa
    11281 aatgtaaaga aaatagatag gattataaaa taactaatgt ttttaatttt gcagaaaatt
    11341 caaaatagct tgaaattcaa taaggtaaat gaaataaaag aaaataactt atttttttga
    11401 tggaaaaaat atgaaaaaac gatgtgtatt aaataaaaga atacacacat aaaataacac
    11461 tgtcttgtaa gtttgttaaa aattgaatat gattacatct ggataacaaa tttttatcat
    11521 aaaggagaga acgaatgaac aacaaacaat tacgctggtt tactgttgcg ttaattgcat
    11581 ttaacatggt ttggggcatg gggaatgtag ttaataacta tgctcagcaa ggagtatcag
    11641 ttgtcacctc ttggctattg attttggcca tttattttat tccatacgca ttgatcgttg
    11701 gacaattagg gtcagccttc aaggatagta aaggaggcgt cagttcatgg gtcgaaaata
    11761 cgacatctaa taaacgactg gcatactatg ccgcttggac ttactgggtc gtccatattc
    11821 cttatttggc acaaaagcct caagcaatcc tgattgctgg cggttgggca gtccaaggaa
    11881 atggaaatat cgtaaatacg atgtcagtac aaatggtagc agttatttca cttattatat
    11941 ttcttgcctt tttatattta tcaacaaaag gactttctac tttgaaagtg attggcggac
    12001 tggccggaac agcgatgttc gtcatgtcga tcttatttat tcttttagct gtaacggcac
    12061 cgttcatcaa tccaacgatg gaatttgcca caccacatat gaatcaagtg aaaacatata
    12121 ttccaacatt tgatttcagt tatttcacaa ccgtttcgat gctagtattt gcagttggag
    12181 gagcggaaaa aatatcccct tatgtcaact ctacaagaaa tcctgcaaag gaatttccta
    12241 aagggatgat cttcttagca gcaatggtag ggatttgtgc tgtattaggc tcagtcgcaa
    12301 tgggtatgct gtttgctagc gataatattc ctaaagactt gatggcaaat ggggcataca
    12361 gtgcttttca aattttaggt aattactatg gtatcggtaa ctcattgatg atcatttacg
    12421 cattgacaaa catgattgga caaatctccg cattagcctt ttcaattgat gcaccactaa
    12481 aaatcttgtt agcagatgcg gatccagaat ttgtaccaaa ctggctacgt aaacgtaatc
    12541 gtaaaggtac attggtgaat ggttatcttc tgacaggtat actagtagga atcattattt
    12601 tgttgccgat ctttggtatc aaagatatga atgaattagt aaaatggttg acgaacttga
    12661 actcagttgt catgccaatg cgttacctat gggtgttctt ggcatatatg atgttgaata
    12721 aagcttataa gaaattcaat tctgaatata aatttgttaa aaatccaaaa atcggtttta
    12781 tctttggtgc ttggtgcttt gccttcactg cgtttgcatg tatcctagga atggtgccaa
    12841 aagtagatta tactgctgat cctaaagcat ggtggttcca attattcacg aatatcatca
    12901 caccaattgt cttgatctta ttaggtatga tcttgccagc aattgctcgt cgagacaaaa
    12961 acaaagaaat cactgaacca gaaacagtgg ttcagcctta aaatagaaat acttgttaca
    13021 agaggttgtg acagaagtgg tcagcttcaa gaaataagaa ggaatttacg aaaattgctt
    13081 ctcaaatttt tgtgaagttt cggcttgttt ttcgcagaag ctacttctgg aacaccgtga
    13141 atcagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa acaaaaatag
    13201 cccctcatat ttttcgtttt gctgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    13261 ttaagaaaga ggtagtgagc ctgccgttta actccgagtc acaaggagca atttcaaaaa
    13321 acaacttctc atgtttgttg actattgtgc cttgtgaccg aggtgttggc aggagaacac
    13381 cgtttaagga agaggttgta aaatcagcga tttgacctga gtattagagg aacaaacgaa
    13441 aaaatagctc ctcatatttt gccgtttttt gagttaatgc tgaaggtcag ctgattgaac
    13501 accatttatt cgaaacaagg gactttgaca cgacttttgt cacagtccct tgtttttttg
    13561 cggcgttata agtggtatga tcgaaccaaa ttccaaagag aagtgaggga gaagaatgaa
    13621 gatcatcgtg attggacaaa gtgggtcggg aaaatcgacc ctcgcaagga agatcaaaga
    13681 aatcaccgac tttccgctac tgccgctaga ccttttatgg catacaacag actacagtat
    13741 tcaggcaaaa aagtggtttt tgcaagaaca gcaatcgttt atggtatcta atccgtcatg
    13801 gattgttgaa ggaaattata cttctacatt agaggaaagg attaaagaag cagataagat
    13861 catttggctt aaagtgccgc gttatctcgc catctaccga gtagtttggc gttctctaaa
    13921 aagaaagata aacaaaaaat ctcggccaga tatgcctgaa tcattttcag agaaactaaa
    13981 cagggaatac ttagaatttt tatcttttat ctggcatttt gaagaaaaca atgaaccgaa
    14041 aatacagcag ctgatccaag tagctaatgc aagaaataaa ctgatcatcc ttaaaacaag
    14101 acgagagaaa caagaatttt taactaaatt gaaaatagag agcaaaaata attgacagtt
    14161 tttgtttaca agcgtaatct gtattcataa gctaatgatt acatttgtaa acgaaaggtg
    14221 tgaaataaat ggaaaaagtc aaaacgccag taaagatcag tgattcagag tgggagatca
    14281 tgcgtgttat ttggacactt ggacagacga cagcccaaga aatcacgcag atcttagctg
    14341 attcgatgga ttggaaacca gcaacgatca aaactttgct gggacgtttg gtaaaaaaag
    14401 aagtgatctg gacagaacaa gaaggaaaaa aattcattta tcatccagct gtctcggaga
    14461 tggaaacagt tcgcagtgcg acggaaaatc ttttttccca tatctgtgca aaaaggattg
    14521 gagagacgat tgcggatcta gtagaagaag ccactttgac tcaagaagat atcaatgaga
    14581 ttttgaaaca actggaacaa aagcaaccag tagatacgat cgaatgtaac tgtatcccag
    14641 gtcaatgtga atgtaaacaa catcaatagg aggaagaaaa aatgaaacaa caattttcaa
    14701 tcgaaggtat gagctgcaat cattgtgcag caagagtaga agaaacagta agcgcacttg
    14761 acggcgtgca aaaagtgaaa gtaaatttga aaaaagcaaa cggtacggtc aagtttgatg
    14821 aaacaaaagt tcaatccgaa aagatttgtc aagcaatcaa tggattgggt tataaagcag
    14881 aggtgatttg atggcaacag cagaaaccaa aatggatacg ttcgtcatta caggtatgac
    14941 ttgtgcaaat tgttctgcta ggatcgaaaa agagctgaac ggacaacctg gtgtggtcaa
    15001 tgccacagtc aacttggcca ctgaaaaagc aagtgtcaaa tatgaaggga cgaccactga
    15061 aaaattaatc caaagcgtag aaaacatcgg ttatggtgca attttgtacg atgaagccca
    15121 caaacaaaaa attgcagaag aaaagcaagc gtatttgaaa aaaatgctat tcgatcttat
    15181 attgagtacg gttttgactt tgccgttgat gttgtcaatg attgctatga tgttaggaag
    15241 ccatgcggcg attgttcact tttttcattt tccaatcgtc cagttagtgc tgtctgctcc
    15301 tgtccaattt tatgtcggtg ctcgttttta taaaggtgcg taccatgcaa tcaagacgaa
    15361 agcaccaaat atggatgtat tggtagcaat tggaacatcg gctgcctttg cattgagcat
    15421 ttacaacgga tttttccgtg gacaccccca agatctttat tttgaaagca gcagtatgat
    15481 catcacgctg attttgctcg gcaaatattt ggaacataca gcaaaaacga aaacaggtaa
    15541 tgcaatcaaa caattgatgt ctcttcaaac aaaaaccgcc caagtgataa gaaacgggaa
    15601 agaagaaacg ttagcgattg aagaagtagt cgttggtgat caactagtca tccgtcctgg
    15661 tgagcagatt ccagcagatg gtcgaattat ttcaggaagc agtgcgatag atgaaagtat
    15721 gcttactggt gaaaatcttc ctgtagaaaa gaatccggat gacacgcttt ttggcgggac
    15781 aatcaatacg aatggtctgc tacacatgga agtcacacaa gtcggcaagc agacagtatt
    15841 agcgcaaatc attcaaatgg tggaagatgc tcaagggagc aaagccccaa tccaaaaaat
    15901 cgcagatcgg atctcaggga tttttgttcc gatcgtatta gtcatcgcgt ttatcacgct
    15961 catagctaca ggtttgatca ctggtgattg gcaactcgca ttgatccata gtgtctctgt
    16021 attagtcatt gcgtgtccat gtgcattagg tttagcgacc ccaacagcta ttatggtagg
    16081 aacgggtgtt ggtgcacgaa atggaatttt aattaaaggc ggagaagcat tagaagcagc
    16141 tgctcactta gacagcattg ttttggataa aactggaacg attacagaag gaaagcccaa
    16201 agttacagat ctagtcggtt caaaagaagt cctatctatt ttttatactt tagaacaagc
    16261 ttctgaacat ccactaggta aagcaatcgt ggaatacgga aaactgcaag aagcagcaac
    16321 atacgatatg attgatttta cagcccaccc aggtgctggg atcagcggta cgattaatgg
    16381 agtacgctat tttgcgggta cacgtaaacg attaattgaa ttgaacctat catttgatga
    16441 ataccaagaa cacgcgttag aattagaaca gcagggaaaa acagtcatgt ttttagctga
    16501 tgaaaagcaa gtgatcgggt ggattgccgt ggctgatcaa atcaaactag aagccaaaca
    16561 agcaatcaag cagctccaga ataaaggatt agatgttttt atgctgacag gagacaacaa
    16621 actggcagcc gaaacgattg gtaaacaagt tggtattgat ccaaagcata tctttgctga
    16681 agtacttcca gaggataaag cagcctacgt agaaaaactt cagaaagatg gcaaaaaagt
    16741 cggtatggca ggcgatggaa tcaatgatgc accggcctta gcattagctg atgtcggtat
    16801 ggcaatggga agtggaacgg acattgcgat ggaaacagcc gatgtgacgc tgatgaatag
    16861 cagtttggca tccattgcac aaacaatcga gttgtctagg ttgacattga gaaaaatcaa
    16921 acaaaatctt ttctgggctt ttgtctataa tacgattggt attccttttg ccgcactagg
    16981 ctttttgaat ccaatcattg caggaggagc gatggcgttt agttccgtca gtgtattgtt
    17041 gaactccctg agcttaaatc gacacatgaa aaagtaagag aagggatgga gtaaaaatga
    17101 atgggaacga tatggagaaa aaacatgagc ataaaaaaga agtagtaaac aaagaaagta
    17161 cagaatctca tgaaaaacag atggagatga aacatgacca tagtcagatg gatcattcca
    17221 tgcacatggg acataaccat ggagatatag caaacagcaa acaaatggac cattcgatgc
    17281 acatggatca cgaacacggc ggcatggatc attccatgca catggggaat ttcaaacaaa
    17341 aattttggct atcgcttatc ctagctatcc caatcattct tttttcacca atgatgggaa
    17401 tggaatttcc atttcaagta acgtttcctg gttctgattg gctcgtattg atcttagcaa
    17461 ctatactatt tatctatggc ggtcagccat ttttaagtgg agctaagatg gaattgaaac
    17521 aaaaaagtcc tgctatgatg acactgatcg cgatggggat tacagttgca tatatttata
    17581 gtgtctattc gtttatcgca aatctgctca atccacatac acacgtcatg gatttcttct
    17641 gggaattggc tactttgatc gttattatgc tactaggtca ctggattgaa atgaatgctg
    17701 tgtcgaatgc cagcaatgct ttacaaaaac tagcagaatt actgccagaa tcagtgaaac
    17761 gcttgacgaa agatggaaaa gaagagacag tttcattgaa agaagtaaac gaaggtgatc
    17821 gtttgatcgt ccggtctggt gataaaatgc caacagatgg tgtaatcttg aaaggtgaaa
    17881 caattgttga cgaatcagct gtgactggcg aatcaagagg aatcaaaaaa caagccaatg
    17941 acaaagtgat tggcggttct atcaatgggg atggaacgat cgaaatcgaa gtaactggaa
    18001 ctggtgaaaa tggttatcta gcgaaggtta tggaaatggt gcgaaaagca caaggagaaa
    18061 aatccaagct agagtcatta tctgacaaag tggcaaaatg gctgttttat gtcgcattaa
    18121 ttgtgggtat cctggcattc atcgcctggt tgttcttgac agatcttcct aatgcattag
    18181 aacgtatggt aacagtcttt atcatcgcct gtcctcatgc tctaggttta gctatcccat
    18241 tagttgttgc tcgctccaca tcaatagcag ctaaaaacgg attacttttg aaaaaccgca
    18301 atgcactgga gcaagccaat gatctagatg tgatcatgct ggacaaaaca ggaacactaa
    18361 cagaaggaaa atttactgta acgggtgtcg aagtacttga tgatgcgttc aataaaaatg
    18421 aaatccttca atatctagga gccttggaag cgaatgccaa tcatccattg gctgttggca
    18481 ttatgaatta tttgaaagaa catgaaatca agccttatca agctgaaaat ctaaaaaatc
    18541 tttcaggagt cgggctagag gcaacagtca aaaaacaaca agtgaaaata gttaatgaaa
    18601 aagaagttga gcgtctcgga ttaaacgtag aacaagcatt attgaaacct taccaagaac
    18661 aaggaaatac catcagcttc ctgattttag aaaatcatct agctgcaatc gttgctttag
    18721 gtgacgtagt aaaaacagaa gcaaaagaat ttatccgaac attgaaagaa agaaaaatca
    18781 ctcctgtcat gcttactggt gacaataaaa acgctgccca agcagtagca gattatttag
    18841 ggatcgaaga atattatggc ggtttattac cagatgataa agaagctgtt gtccagaaat
    18901 accttgacca agggaaaaaa gtaatcatgg tgggtgatgg gatcaatgat gcgccaagtt
    18961 tagcccgtgc ttcaatcggg atggcaatcg gtgcagggac agatatcgca atcgattctg
    19021 cggatgtcgt attgacaaac agcgatccaa aagatatttt gcattttctt gatctagcca
    19081 agcaaacgcg aaagaaaatg atccagaacc tctggtgggg ggcaggttac aatattcttg
    19141 caattccgct agcagccgga attcttgcgc caattggtat catattaagt ccagcagttg
    19201 gtgctgtctt gatgtcgtta agtacggtag ttgtagctct aaatgctttg acattgaaaa
    19261 tcaaataata atgaaaaaa
//
LOCUS       DACBYO010000052        19083 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.052, whole genome shotgun sequence.
ACCESSION   DACBYO010000052 DACBYO010000000
VERSION     DACBYO010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19083
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.052"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            434..664
                     /locus_tag="IVD26_001785"
     CDS             434..664
                     /locus_tag="IVD26_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079733.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            823..1656
                     /locus_tag="IVD26_001786"
     CDS             823..1656
                     /locus_tag="IVD26_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HAP6079734.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            1649..3064
                     /locus_tag="IVD26_001787"
     CDS             1649..3064
                     /locus_tag="IVD26_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP6079735.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            3076..4605
                     /locus_tag="IVD26_001788"
     CDS             3076..4605
                     /locus_tag="IVD26_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP6079736.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            4697..5575
                     /locus_tag="IVD26_001789"
     CDS             4697..5575
                     /locus_tag="IVD26_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAP6079737.1"
                     /translation="MMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            5577..5894
                     /locus_tag="IVD26_001790"
     CDS             5577..5894
                     /locus_tag="IVD26_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079738.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            5943..6644
                     /locus_tag="IVD26_001791"
     CDS             5943..6644
                     /locus_tag="IVD26_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAP6079739.1"
                     /translation="MVEWWGATIKTQSNAGRENESWGERRMSMKHKSLMPMNLQYFAE
                     GDDQKFSFDDFKSFVESNEEAQKFIQSQSQSVADKQLEAWKQNNLDKIKQDTIKEYEE
                     SKKNKSPEQIQLEKLQAEFEAEKALRVTSDNKAFVAEQIAGLELDGELKESISQFMLN
                     NLVSSDTDFTKNAVEGFTSVLNAINEKHADALKELQMKSAFGGTQQSNNQVQQNNETL
                     TNPEEQLGQILQQFN"
     gene            6659..7549
                     /locus_tag="IVD26_001792"
     CDS             6659..7549
                     /locus_tag="IVD26_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HAP6079740.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            7572..7787
                     /locus_tag="IVD26_001793"
     CDS             7572..7787
                     /locus_tag="IVD26_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079741.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            7799..8140
                     /locus_tag="IVD26_001794"
     CDS             7799..8140
                     /locus_tag="IVD26_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079742.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            8140..8511
                     /locus_tag="IVD26_001795"
     CDS             8140..8511
                     /locus_tag="IVD26_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079743.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            8504..8899
                     /locus_tag="IVD26_001796"
     CDS             8504..8899
                     /locus_tag="IVD26_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAP6079744.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            8901..9278
                     /locus_tag="IVD26_001797"
     CDS             8901..9278
                     /locus_tag="IVD26_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079745.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            9279..9887
                     /locus_tag="IVD26_001798"
     CDS             9279..9887
                     /locus_tag="IVD26_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP6079746.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            9887..10228
                     /locus_tag="IVD26_001799"
     CDS             9887..10228
                     /locus_tag="IVD26_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079747.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            10470..13259
                     /locus_tag="IVD26_001800"
     CDS             10470..13259
                     /locus_tag="IVD26_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAP6079748.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            13249..13989
                     /locus_tag="IVD26_001801"
     CDS             13249..13989
                     /locus_tag="IVD26_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP6079749.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            13986..16748
                     /locus_tag="IVD26_001802"
     CDS             13986..16748
                     /locus_tag="IVD26_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAP6079750.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYE
                     RPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYS
                     GYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIIN
                     WARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            16761..17669
                     /locus_tag="IVD26_001803"
     CDS             16761..17669
                     /locus_tag="IVD26_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAP6079751.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            17669..18289
                     /locus_tag="IVD26_001804"
     CDS             17669..18289
                     /locus_tag="IVD26_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079752.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            18293..18742
                     /locus_tag="IVD26_001805"
     CDS             18293..18742
                     /locus_tag="IVD26_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079753.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKAKLDGLANITFEKVGTV"
     gene            18742..>19083
                     /locus_tag="IVD26_001806"
     CDS             18742..>19083
                     /locus_tag="IVD26_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079754.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYR"
BASE COUNT         6897 a         2614 c         3962 g         5610 t
ORIGIN      
        1 aatgattcca ttaataattt caatttttgc gctttgtctt aatgtatata tgattggatt
       61 taaaaatggg caaaataaaa aatagtagca gccaagaata attttatagt gtcactgtgg
      121 cggaaagggt agacgctaag catgtgtgct aggtcaatgc ttcggcaacc atgcaaggtt
      181 cgattccttg ccagtgactt tggcaaccga ggcatcggcg gtttaaaaat ataggggtgc
      241 gcaatttcgt acgcgttttg tgcatcgtgt aggttgctat tacataactg gttaggttag
      301 attgagattt gggattcggt acaaatgaat cgtcaaatgt ctcaagcaca ggatcggaaa
      361 cgtccctgcc tgtgcattac atattagatc actctttgag tggtcttttt ctttacataa
      421 aggaggctac ataatgagaa actactggta tgtatcgcta actaatgaat atcctcgaac
      481 cattgatgat tgttcagtgc gtgttgtgcg ttctgtacaa atcaaaggga agtactctat
      541 tgtcgaaatg gggagagaag cagaaccatg tgagattgat gcgtgcaagc tcgtttattg
      601 cggtcatggt ttctatgatg aaccaaacat tcaaaataat attaacaaga atttgaggga
      661 ttagaatgca agaaatggct taaaaatctc caatcaggac aaatcaagtt agacaaagtt
      721 tccgatttaa agatattgat tgaagctgat ttaatgctaa aagatattga aaattagaaa
      781 acaaaactca acctaaacag aatgtgaggt ggtgtgtatt gaatggcaag acaacgtgat
      841 ccaagacgtg atgaagccaa aagaatttgg ttagaatcca acggagaaaa gcagttaaag
      901 gaaattgcat ctgaattaaa tgtttcagat tctcaggtta gaaaatggaa atcgcaagac
      961 aaatggagcg ctgaattgat tagtaacgtt accaatggca aaagtaacgt tactaatcaa
     1021 ggtggcgctc ctattggtaa tcaaaatgct aaaggtaaca aaggaaatag ccgagcttct
     1081 ccgccagtgg gtaataaaaa cgctttgaaa acaggtgagt atgaaacaat attttttgac
     1141 acgttaaccg ataatgagaa ggacatctat tctagtttga atgatgatcc ttcttttgct
     1201 ttgtccgaag aaatacgact tcttaaaata agacaacttc gaatgatgaa aagaatccaa
     1261 caagctgaag ctggactaaa tgatgaagaa gtcgaacgat tgcagcagct aagaaagatt
     1321 aaaactccga ttgaaaaaaa tggtaaaaag ctagaaatca agcgtgaggt tatgcaagat
     1381 gtgcagatta gcagaaaaaa acatcgcaaa attgatgata ttctttcaat tgaagattca
     1441 ttgactcgga ttagcaacca gttagctaaa gccatcaagc aaatgaatga actttatatg
     1501 aatgaataca gaactgattt aattaaagct cagactgata agatccaagc tgagacaaat
     1561 gaaattggcg gaaataattc aggtgaagaa atagaagaat ggaaacaggc agttttaaat
     1621 gccgcaaaca aacgggcggt gaaagaaaat gaataatgaa tttattcctt ttgctgatat
     1681 tggttctgcc attgattatt actatgataa accagtagct ttttgccaag atattttgca
     1741 tttgaatcct gatgaatggc aagaaaatgt tttaaatgat ttagctgaat tttcaaaggt
     1801 ttctgttcgt tctggtcaag gagttggaaa aacagcatta gaagcaggag caatactttg
     1861 gttcttaacg tgtcgaccct acgctaaagt aatagcaaca gctccgacaa tgaagcaact
     1921 ttacgatgta ctttgggcag aggtagctaa atggttaaat gatagcttga tcaaaaactt
     1981 actgaagtgg acaaagacca aaatttatat ggttggtgat tcagagcgtt ggtttgctac
     2041 ggctagaaca gcgactaaac cagaaagtat gcaaggtttt cacgaggacc atatgttgat
     2101 tgtggtagat gaagcttctg gtgtgtctga tccaattatg gaagctattc ttggtacgct
     2161 atcaggtttt gataataagc tgttgatgtg tggaaacccc aataatattg aaggtgtctt
     2221 ttatgattcc cataattcag accgtgataa atacagagtt cataaagtat caagctatga
     2281 tagtaaacgt acaaacaaag acaatataga aatgattctt aaaaaatatg gaaaagaaag
     2341 tgatgttgct cgtgtccgta tttttggaga atttccgaaa ggtgcgttgg attcatttat
     2401 cagtcttgaa acagttgaat tggctacaga aaaacaaatt agtgattctt tagtcaataa
     2461 aacaaaggtt gctcatattg gtgtcgacgt agctcgatat ggtgatgatt ctacgattct
     2521 ctttcctaga attgctacca gggcattgga gtatgagaag tattcaaaac gtagcaccat
     2581 ggaaacaaca ggatatgtca tcaacatggc caagaatcta atgagtcaat atccgagtat
     2641 tgataaagtg atgattaaag tcgatgacac tggtgtcgga ggtggtgtaa ccgaccgcct
     2701 agaagaactt atagaagaca aacattatcc ttttgaggtg tttggagtga ataacggttc
     2761 aacatcagaa gacgattttt acgataattt aggtactcaa ctatggggaa acatcaagga
     2821 aatgttagaa gaaaatatga cagcaaatct taacggagaa cagcctgtta ttgaattgcc
     2881 ttctgatagt tcgttaatca aagaattaag tactcgcaaa ttcaaaatga caagtagaag
     2941 tcgtatacgt ttagaaagta aagatgatat gaaaaagcga aatattggta gtcccgatat
     3001 tgctgacgca ctggctttag cgttttatga gccaccaagt cactatcaat ttattcaatt
     3061 ttaggaggtg agcttttgat tagtacagta ttatctttag agagatataa gaagctacgt
     3121 gttaaatatg caacacaaat tgaagatgga atgtttgatc cgaatggttt tatagaagat
     3181 atgaaaccat tttttgctga tcgcgaaaga aaatatctag cttatactag cgaaaagaat
     3241 gaaatagata atagaccaaa gcctaacact gatattgtaa aagttaataa taaacttcat
     3301 gctggtatgt attcaattgt cgtagaccaa gcagtcaatc attttactgg tatacctatc
     3361 aaatgggatt acgatgtatc ggaacaaaaa agaacactca ttcaaagatt aaaagataaa
     3421 ttcttaaaaa atgatataga acttccgaca gttccagaag cttttaacaa attaacaagc
     3481 aatcttgatt ccatgagatt cgcaatgctt gattctgaaa ctgcaacttt tcaaggagct
     3541 tgtggagtag ctttccgatt gctagagcct gtggaagaag atgatggttg gaagttaaga
     3601 gcaagtaata ttgaaccttg gagagcagaa agatatggaa atgccggaat ctatatcaaa
     3661 gaaaagtatg actcttacca gaaaaaattt tttcaagaaa tgaaagttat gacaagaaat
     3721 aaaattctga catatgcttg ctatggtgat ttgaattttg ttacaagcgg aacgttcaaa
     3781 aaaattgatg agaccgataa ccctttgggg acgattacct tggcagaatt taaaaataat
     3841 acgaatcgtt attgtgattt tgaagtagct gaggaaattg gagatgcaat tgatcgtgct
     3901 ttgtctgatc aacaaaacga aatcgaacaa tttaagcttg cgtacatgct tgttactggc
     3961 acaacaatga gcaaaggcac tgctaaagaa atgatgaatc agctagggat tatcaactta
     4021 aaagccccta ctgcaaaagc tgaatatgtc acaaaaaatt tagcaaaaga tttcaatgaa
     4081 tatcatatgg atctattgaa aaaacagttt tacaccattt gtaaagcaat cgattttaac
     4141 gatgaggtgt ttaaatcaaa cagttctgga gaagctcgca agtggcaaat cattagccta
     4201 gaagcgaaaa caaatactaa agagcaatat tttagagaag gattgaaaga atgcgcagaa
     4261 acaattgctg cttttcttaa gtttcatgac aaagtagaaa ttgagcctga aaaaattatt
     4321 tttactttct ctagatcttt gccaactgat ttaagttatt tagctgaagc tttacctaaa
     4381 cttgcaccat acgtatccaa acgaactatt cagagccaaa ttccatttgt aacagatgtt
     4441 gattatgaaa atgaaatgat ggaattggaa agtggaagtg cttatccaga tagtgaatac
     4501 aattttggcg gaggtggcaa tagtgacgat agaaacgaag tattggacca aacgtcgaga
     4561 actggaggat caagcaaggc tcaaacaaga aaatcagaca cttaaaaaat taactagtgt
     4621 atttcctgaa gcactgaaag agatacaagc aaaactatta tcacaagctg acttacacaa
     4681 tatcacttat ccagaaatga tggagtttta cagtacaagt aatcagaaaa aatatcgtga
     4741 atatgtggaa aaaaattata agtcattaaa aatgtatgat gcaaaataca aagagtttat
     4801 cgatgaattt tttccaccat ttgactatgc aaaagtcaat cgcttattac aaatacgatc
     4861 agatgtattt aaaattcttg cagaatatgc gatggatgca gatgtgaatc aatatttttc
     4921 tgatcgctta gaggaaattc ttcaaagaac atattcttct aatgctaatg tttttgttca
     4981 acttttaaac gttgatatac caaattattt accagaaaat gaaattaaac attatttgaa
     5041 ctatccatgg tcaggaaaga cattttcaag aagactttgg ggaaatattt catcgcttga
     5101 acagaaactc tctaatgcta ttgtaaaaag tgttgctagt ggagaaggcg ttatacacgc
     5161 attaaacacc atgagattag actcagaaat ttgtgacatg tttaagttag aagaatcaaa
     5221 gtataacaaa gcgatagaaa atctcgttcg aacggagtat gcaaaatttg cacaagatgg
     5281 tattgaaaaa tcatatttag aaacaggtat tgaggaatac aacgtattga ctgcaaaaga
     5341 tgagagagtt tgccggattt gtggaggaaa ggcaagtaag aatccctata aactgaaaga
     5401 tgctgtcata ggtgaaaatc gagcaccttt ccatagtcgt tgtagatgta cggatgttcc
     5461 taatttacca aaattaggaa aggatattga tgaagaatat gaccgtttat ttggcgattt
     5521 attagatgag tttgcacatg attcttttgg aattaatttg aaacggagga agtagaatga
     5581 aagatttttt tgaagcagta ctaacaatta atgtaaatgc tgatattgca gaagcctaca
     5641 aaacagctat tgagtctgag aaccatccta atggcttgag agaccattgg aatggcaatt
     5701 atgcctacgt ggttattggc gatcaaactg ttaattatca agataatact ccagttgata
     5761 agaataccgt taatttaacg attcaattat tatctcattc attaccaaat ttaaaagaaa
     5821 cagttgattg gtatgaaaag atgggatgta ttgttgttag aactgactac aaagaaggaa
     5881 agtctagtaa ttaggctttt ttattttgtc cgaaatgacg ttaaactagc gcaatactgg
     5941 gcttggttga atggtggggc gcaactatta aaactcaaag caatgcgggg cgtgaaaacg
     6001 aatcgtgggg cgaaaggaga atgagcatga aacacaaatc attaatgcca atgaatttgc
     6061 aatactttgc cgaaggtgac gatcaaaagt tttcttttga tgacttcaaa tcttttgtgg
     6121 aatccaatga agaagctcaa aaatttattc agtcacaatc tcaaagtgtt gccgacaaac
     6181 aattggaagc ttggaaacaa aataacttag ataaaattaa acaggatacc atcaaggaat
     6241 atgaggaatc taagaaaaac aagtcacctg agcaaattca actggaaaaa ctacaagctg
     6301 aatttgaagc agaaaaagcg ttgcgtgtga caagtgataa taaagcattt gttgcagaac
     6361 aaattgctgg attagaacta gatggagagt taaaagagtc tatttctcaa tttatgctaa
     6421 ataatcttgt tagttcggat acagatttca ctaagaatgc tgttgaaggt tttacaagtg
     6481 ttttgaatgc aattaatgag aaacatgcag atgcattaaa agaactacaa atgaagtctg
     6541 catttggtgg aactcaacaa tcgaataacc aggttcagca gaacaatgaa acattaacaa
     6601 atccagaaga acaattagga caaattcttc aacaatttaa ctaggagagt gaaaaattat
     6661 gaaaaaaaca tctttaaata atttagagta tttggatatt tcaccagcga ttaatgctat
     6721 gcaagtacca aatacacctt ttttaagcta tttacttggt gctggaaaaa cagagccagc
     6781 aaactcgaca gaaattaaat ggcgtgaata tgatatcaac aacgatgatt cttctgaaaa
     6841 acttgagggc ggagaatatc cagatgctga atcaggtcga acttggttta acaactatac
     6901 tgaaattttt agaaaatcaa cctctgtatc tggtacatta gatgctatta atgtgaatgg
     6961 agtcggaaat gaattaacta atcaagtagc actacgtggt atggaaatga aaattgattt
     7021 gaaccgaaaa ttgattactg gtgtaaaagc tgatgaaaat ggttctaaag gtcgtcgaat
     7081 gaatgggatt ttgaacttga tcaattcagc aaataaggca gaaacagcca ctgcgggtgc
     7141 agtaacaaga aaagatatcg atactttatt taaattgatg tatgaaaaag gttatatggg
     7201 agaaaaacta tgcttgattt ctccagatat gcaggagtta atgactgatg agttagatgg
     7261 aaaatcaaca aaaattgttc agttcgggga aagagtaact tttggattgc aaattggaaa
     7321 tatcgtgtct aattacggta caggtattgc tctactagaa ccatcattgc caaaaggaac
     7381 aattgccgca atcgatacta attatgtgaa actacgtcca ttacgtgaat ggagagcaga
     7441 agaacttgca aaaacaacgg attctagacg tatcggtctt gtaggtgaat actctcttga
     7501 atacaatgct tcaaactctg gggcaatttt aaatttaaag tctgaataaa agggagttag
     7561 tactcccttt tttgatagga ggaattacag tggtaaaaaa agatgaaact aaaaaagatg
     7621 aagtcgtgaa atatagagta ggtaaaacta aaaattttgt tgggtttgtt catcctaaaa
     7681 ctcgtagatt tatcacagca gattcaaata acgaatttat catttctata gatgataaag
     7741 aagcaattgc aattttggaa gatgcaattg atgttaatga aatttaggaa gtgatctgat
     7801 ggatgaatcg ctaaaaacgg aaatcattga gtctacaaaa gaagattttc cagatttgag
     7861 tgaagaacgc ataactaatt tattagaaat aattttgcta gaaattgaat catacaacac
     7921 ttgtaaaaat gatatttcat gggaaaagtt aaaaagcgtg attagtgaag tgttgtataa
     7981 aataataaaa aatgaatcag aaaaaacagt atcttcagtt agacgtggcg atacaacgat
     8041 tagttatgct tcaacaacaa atgatgttag tgagttactt ctaggctatg gtgatttgat
     8101 acgaagagtt attggttgtg gaggattgga gtttttttaa tgaatgaagc agatatttta
     8161 gaaactactt atgaagatag ttgtattatt gaaagactga cggacattga agattctaat
     8221 acaaatatta ctattcaaga ttacaaaaaa gtatatgata atcctatttc ttgcgctctt
     8281 tcacaaggtc aaatcgatgg actagcagtc atagaagatg gagagatggt aaatgtttca
     8341 actgacacat ataaattatt tgttcatcct aagattaaac taaaaaaagg agatcgaata
     8401 acaataactc aaaaggccag tggcttaatt ttttctctat ttgctactaa gcctttttac
     8461 tatcctagtc attgtgaagt gaatttgata ggaagtgaga aaaatgggta atctcaaata
     8521 tgaatcaaat gcagaaaaga tcattgagaa ttttaaaaat atgactgtaa ttgctcaaaa
     8581 agaaggaata tccttcgtta acgattcaat gaataaagtc gttagtttag ctaaaccatt
     8641 aactcctgta aaatcaggta atttaaggcg aggatatcgt gtagtaaaag ctagaaaact
     8701 atcaagcggt cgaattgttg gagaagttat aaacaatgaa cattatttta aatatgtaga
     8761 agaaggtcat aggactaaaa atggtggctt tgtcaaaggg aaattcatgt taactcgtgc
     8821 aacgaatctt gcaaatatgt cttatattcc tcgaagattt aaacaaatgg caataaaaat
     8881 cgttaagaaa ggaaagtaac atgaaagatg aaatcattgc tgcaatcagt agcaaattaa
     8941 aagaaatcta tcctgatggg acaatatatc ttgattcagt tatgcagtca actaaagatt
     9001 tttatttcgt tttatcagta atggaatctg gaactgaaaa tgtaggaatt gatattcaaa
     9061 atgtttcttt cttaattgat attgcattga ttgataataa ccctaataga aatttaatta
     9121 atgaattagt ctcacgttgt gggacttttt ttaatacgat tacaatcgat gagcaaatat
     9181 tatttccaaa agcctattta cctgatgaag cagatggtgt tcaacatatt cgttttacat
     9241 tagaatttcc acaatatatt gaatggagtg aaagataaat gggagaaaaa agaagtaaaa
     9301 ccggaattat ttctgtcgaa aaacctactt ggtttccttt ggaagatgag acagggaatt
     9361 ttccggtata tggtactgcg ttgccaatgg gaacagcagt aagtatcaaa ccaacagcta
     9421 attatgaaac aacacaagat tatggggatt cagtggttca agatcaattt acagcttttg
     9481 gtggtgcaga agttgaactg gaagcaaatg gatatactca taaagtttta tctacaatta
     9541 ctggagggaa aattgttaaa ggtggtgcct tgcgttctgg agaagatatt gcgcaagatg
     9601 gtgcgtttgc atatagacgt aaaaaatcga atgggaaata ccgttatacg gtcttttata
     9661 aaggacagtt tgctctagat tcagatgaaa catcaacgat tgaaggaagt aaagtaagtt
     9721 ttactcatcc aacttggaag ggttcatttg tagatgtacc aggacttgga tatatgtatt
     9781 cagttgatga agatgatgaa ggcgtggata aagcaatgat cggaaattgg tttacaaaag
     9841 tagcaattcc aattgaagaa gcagaacttt caggaggtac agaataatgt caaaatatca
     9901 aacaacgatt aaattaacga aaaaagacga agaaggtaaa tatgagcaag tacaatttaa
     9961 atctgctgaa tttttaccag gaacagttgt agaagatgct gcaggagtta tggaagaaat
    10021 gcaaacagcg actgataagc aatcagttaa aaaagcttta agtcgtgctt attcatttat
    10081 tgcagatact ttatttgagg gacaatttac tggtgaagat tattgcaaag gaattgatgc
    10141 tcgtgagatt gcctcattga caggaaaatt attgaagtct gttactgcag gttttgatga
    10201 aacttataca gagacgaaaa aaaagtaagt gaggcgctca agtcaccttc atttaagtat
    10261 tcgattactt accgagaatt agatataaag acgcaattac tcgaagcagg ttggacgtta
    10321 ccagaaattg aacgtactga cttggatgag ttaatgcgtc tttttgcttt tagagatgcg
    10381 gtaaaagagc atgaagatgt tgagtactat gataatttca ctcaatttta ggaggtgata
    10441 ctttgaataa cgatgaccta attctgaaga tgatactaga tgaatctggt tttactgccg
    10501 gtatgaataa tgctgtcaaa aagttgaact cttttgatga aacaatcgaa agaaaaagta
    10561 gaaatagtgg cagttcatta ggtagtattt ggaaaatatt tgctggaagt tttctagcta
    10621 gcggagtaac tagaatcgta ggagctggct ttgatctaat caagggttcc ataagtggag
    10681 cggttgatcg agtagatacg atgaataacg ctctacgaaa tttccaaaat atgggattta
    10741 gtaattcaga aattatgaag aatatcggaa agaatgggct tttatctcaa ggtattcaag
    10801 gacttcctac tgctttgaat gatgcgataa gtcatgttca acttcttgct tcttctacag
    10861 gtgatttaac tcgttcaact caaatattta aagctttaaa tgatggaatt cttggtttcg
    10921 gtggttcaac tgatcaagtt aatgaagctg ttattcaatt atctcaaagt ttctcaaacg
    10981 gaaaagtaga cgcacaaact tggaactcaa tgatcaacgc tcaacttgga cctactcttt
    11041 ctgctattgc taaaaagatg ggaattacaa tgggagatct gaaagaaggt ttatctcaag
    11101 gtaagatttc tgttgaagaa ttccaaaatc aattaataga aatggatacc aaaggtggcg
    11161 gaggacttaa atcattaagt caaatcgcta aagattctac taagggaatt aaaacctcta
    11221 tacaaaatgc aaaaacagct gttacacgtg gtgttggtga ggtaatagaa ggattaaata
    11281 aagcattagt agattcagat ttaggtggat ttaagggaat tattgataaa gtgggcagtt
    11341 caatggaatc gttcttaaaa gtaattgctg caaatattcc tacagcagta tcatttttaa
    11401 gtaatttatt taacgaaatt caaaaatttg gttctgcttt gaaattcatg atgccctttc
    11461 ttgttcctgc agctaccgct tttggagcgt tcatgtttca acttaaaggt ataccagcaa
    11521 taataaaaag cttcaataat tttaagaatg ccataattgg cgttggaaat tcattaaaga
    11581 ttatgggggc aatagctgct gctaatccat ttgttttaat tattggtgca gtcgttggtg
    11641 caatagctgt tttcggttac tttatggcaa ccaatgaaga gcttagaaac aaggttatat
    11701 ctatttggaa tgatgtgaaa gattccgtaa ttggtgtatt aaaaaatata aaggactggg
    11761 gaattgatac ttggaattct gctaaagaaa tggcatcaaa tgcagttgag ggtgtcaaag
    11821 atgcttggtc aggaacaaag gaatggtttt ctaacacctg gaaaggtatt aaggatgggg
    11881 ccacaggttt atttgataaa acagtagaga cttcaagaaa tgcagtcgat agtgtaaaaa
    11941 atgcatggtc taatatgaag aaatggtttt ctgatacttg gcaaagtata aaagattcag
    12001 ccagagaaaa atggaatgga atcaaaggtt ctattatgtc agttgctggt ccattgatta
    12061 caggtataaa gaatgcattt ttacatgtta ctttttatct agagacctta tggaataatt
    12121 tagttgagat tggtaaaaac gtctttgaga ttttaaaaaa tgttatactt gcgccggttt
    12181 tgtttattac ctccatgatt tctggtggat gggaagaaac aaaaaataat atgattgctg
    12241 tttggaataa tattaaagaa agtgccataa atatttggga atctataaag aatatatttg
    12301 taagttattt tacaaatatt tattttgctg cactcaatat ttggacaggg ttcaagctta
    12361 cattgataaa tatttggaat gaagtggtaa atcaagctaa atcgatttgg ttaaacataa
    12421 agtatttttt tattaatctt tggattgata taaaatattt tgcaattcag aaatggattg
    12481 aattgaagtt ttctattatt caaacttgga tcgatttaaa atataatgcc attactactt
    12541 ggaataatat taaacagttt ttcaaagata cttggaaaaa tattaaagat acggcataca
    12601 atacgtggat ttctataaaa aataccatga ttaatacatg gaataacatt aaggactctt
    12661 tctggaatat tgttactgga attgttaatt ctgctgaaaa tgcatggaca aatctaaaaa
    12721 atggtgtttc aaatgctatt aatcgggtaa aagaaatctt taattcgtta agggaagtca
    12781 atttatttga aattggcaag aacatcattg atggacttat aaatggtgta aaagaaaagt
    12841 ggaatgcttt gaaagatact atcaaaggta ttgcaggtaa tatcaaaaat tggattaaag
    12901 gagctttaga tattcattct ccatcaagat ggatgcgtga tatggttggt aaaaatattg
    12961 ttcaaggtat tatcgttggt attgataaag agcaaagtaa gttagatcaa accatgacaa
    13021 atttagtaaa aacaccgtct gttcaacctg tagtaaatgg aataagtcac ctaccaatta
    13081 cacaaacaaa gcaaaatata tctgctagtg aaacaaaaga aattcattta catttaaatg
    13141 tttatggaga tttacctgat tcaatggttc ggaagattac cacaaaaatt aaaacagaat
    13201 tgacaagaca aatgaaacga gatgctggtg cagtaggagg aacattatat gcaacttaag
    13261 agaggacaat tttttattaa tcaacattat tcttctgaat ttaatgtgta tattcaaaac
    13321 aggcctgctt ctgtttcagc tagtcgagta attgaattga gagagcgaga aggaaatgat
    13381 tctatcatta ttgataaagg ctattacaaa aatgtgacta gaaagattga gtgttactat
    13441 aaagcacctt caattgatat ggtgcaggag tgggaagatc gaatcactga atggttagat
    13501 atgtcgtctt atagtgattt tattctttac tatgatgaac aatatattta tcaagctgta
    13561 gtaatagaag gacctgaatt taaaggaaca agaaaaacag gaaatattgt cccttttgaa
    13621 tttacagtga gtattcgacc atttaaggaa aattacaatg gtagatttac tattcgacaa
    13681 acagaaactt ttgaaattta taacccagag aagtattctt caaaaccgct tattaaattg
    13741 agtggttctg gagatgcttc tttttatatt aataaggata aatatgattt gaaatcgttg
    13801 gacagagaat tatttataga ttctaaatta gaagaggctt atcgaaaatt agatggtaat
    13861 ttagaacatc aggatcaggt caccttattt ttagattttc catttttata tcctggaaaa
    13921 aatgaaatta aatggacgaa aaatattcat tcatttgaaa taatgcctag gtggtggaga
    13981 aaagtatgaa accaagaata tatagtccta ctgaaacaga tttctcaacg aatggcttag
    14041 gaattttaaa ggattgtaca agatgtggaa tatatgaagt agctaatgga aaatatgaat
    14101 tagagttgga ttatccttta ggaactagat ttgatgaata ttttgaaaat gactatcaaa
    14161 taaaagcaaa gccaaacgat caagaagagt atcatatctt ttttattgat gataaagata
    14221 tagatacttt tttaaataca gtaactattt atgctcagag tcgtacaaat cgacttggaa
    14281 gacgggtagt cactcttgtg gaagtggact ctaaaactgg tcaagaagcg atatcaatta
    14341 ttgaaactaa aatggataaa aaatctgaca tacgacttta ttctgatatt acggctgttt
    14401 ctagcacaat ctttgaagcg agaaatgttt taaattgtat tgctggtgaa caaggatcat
    14461 tgcttcaata ttggggcgga gaaattaaac gtgaaccatt taagctttct ttgttaaagc
    14521 gaagaggtcg caataatgtt ggaacgattc ggtatggaaa agatatgtct ggtttgaagg
    14581 tcaaattaga ttggacaggt ataaaaacaa gaattattcc atatgctgat cctcaaagtg
    14641 aagtaggtac gactaatcga atttatggtt cgccagtaga tagtgcctat attaataact
    14701 atcctgatgt ctatacagaa catgttcagt ttacagaaga acaaggagta aaagacatta
    14761 agagcttaaa taaaatagct aaaaattact ttaaaacgat caatcctggc tgtgataagc
    14821 ctaaagtttc tattacggtt gaatttgata agttgactga tagtgaagaa gcgaaagaat
    14881 ttgcgaagat tagaaattat ggtctgtttg atacatttaa aatatatcat aaaaaatata
    14941 atatttatct tgaatcaaag gttagtggac tacaatacga ttctttatct gaaaaaactt
    15001 tgaaattaga agcaggagac attcaagttg ctttttatca gcaacaagct gtaactattc
    15061 aggataaatt aaaagattat gcaacgaata attatatgag tgattttaat gattatgttt
    15121 cttcaatgat tacaggtcaa ggcagtgcag gaggatatgt agttttatgg ccaaaagaaa
    15181 aaccttccaa catctttatt atggataatc cagatttaga aaaggcaaga gaagtactaa
    15241 gaatgaataa aaatgggatt gctttttcta agaaaggatg gcgggggcct tttaattcag
    15301 cttggacatt agatagtata tttaatgcca attttataca aactggatta atcaaagcag
    15361 atatctttca aaattctttt aacaagactg gagatgtatt gaaattagtt aatggactac
    15421 tccaaatttg gaacaacaaa aagaaaataa tggagttaac taaaaaagga atggaatttt
    15481 ggaattctaa gggttcaatt ggaacgattg gaacaactga ttctgttggt aatccttttc
    15541 ctggggcttc tactccaacc cctattgaag ataattcttt agttattcgt acaaatggag
    15601 acggcaaata tattttgatt tctcctaaag taggaaaagg attagtttta ttaggaaatg
    15661 gtaaagcaat ttattttgga gacttagatg tacaaggaaa acttacagtt aaaggaaaag
    15721 aaataattcc tggacaaggt ggtggtccat cgggaggtgg agaatctact ggtgggtatc
    15781 ctagtgaatt aaaaacagat gcagaaaaga gagcttggag aatttacgat attttgtgta
    15841 ataacggatt tacgaaacaa tctgcatgtg gaatattggg gaacattcaa caagaaacag
    15901 gaggaacttt tgatcctgat actgttcaaa taggtggacc agcatacgga ttagttcagt
    15961 gggatggttc ttcatatcct cttgttggtc cagcaacatg ggatggaaaa gtttatgttc
    16021 aaaacttatt taatgctgca ggtattaaag aaccaataac gagcttagat gcacaagttc
    16081 gattgcttat ttggacattt acaaatggac aatggatggg cgtagtacaa cctacgacgg
    16141 ttgatggatt taaggcctgt actgatccaa gacaagcagc atatgctttt gaacgaaact
    16201 atgaacgtcc ggcagcgaca catcctgaac gtcaagatta tgcagttaac tggtataaca
    16261 aatttaaaga tttaaaacca ggaggagcta ctggagaagc aggactaaaa catttagagt
    16321 ctttgattgg acaacgaatt ggcaatggtc agtgttatgg cttgtctgca gaatattcag
    16381 gatatctggg tggttgtggc atgggtgctg gaacaaaata tggtttaact catgtgatag
    16441 gaaatacttc tgcagcatct gatattggta ttgcctatga ttggtctgct gttggttgga
    16501 aagtgattca aaaccctaga tatgatcaat tagtagttgg tgcaattatt aattgggcaa
    16561 gaggtggaca agtgggttca tggtttgcag atggaactta tggacatact ggcgttatcc
    16621 gaggcttagc taatggtcgt atgcaaactt atgaacaaaa cacagagtta ggtatgattt
    16681 gtggaaagtt agatcgccag tattatagtg caagtgcaat ttcttccatt gtcataccac
    16741 caaaataggg aggtgattta atggcaaagt ggaatgtcat attaagtaca acagaaccct
    16801 ataattacgt ggggatgatt caagttcgac aaggcaataa gaatacagag gttatggaag
    16861 cgactatagt tgaaaatggt cttccctacg atttatcaga atgtaaggta tattttgaat
    16921 cagttgtagg tgggaaatat ccagtccaat tagaaacaaa aattgtggat gctaaaaaag
    16981 ggaaaatcaa atatattttt gataaatatt ccatgcagtg tttacatcga caaacagcca
    17041 atttcattat atttaaagga gaagacttga ttggaacaac tcaagacttc tcttattttg
    17101 tcattaatgc tgtttcaaaa acagaaggag aaatgggttc ttattggcaa tcaatcgaag
    17161 atttaattgc ggatatgacg gactttatta atgaaaataa aggcgatttt acggactgga
    17221 tgaatgaaag gaaagaagaa tttgaacgtt ggagacaaga acaggaacac agtttccaag
    17281 attggagaga aggacaagaa tcagactatt tggcatggtt tgaatcaatc aaggatattt
    17341 taaagacgat tgatccaggt ggagtcatgt tagccgaact aacggatgcg cgagtagata
    17401 ttcaaggagt tcgtcatgcg tctatttcag agcgtttgct ggcagatatg gactatttat
    17461 atcagaaatt gcgagcaacg cttttcacga ttgaatacgg ggagattgaa gtgactgata
    17521 ttttgcagga tgatctcttt tcagataatc atgaagtcga aaaagttgga actgtagcat
    17581 tcccgattga agaaggagcc ttgatcatcg caaccgttga tgatccaaag caaaatgtgt
    17641 tcactcttga gaaagttggg gtgatctaat ggctaaaact aaacgaatga tggaaacgga
    17701 tgaaaaaacg ggtgtacaac gccaattctt tccaatcaca catgcttccg cagttcttgg
    17761 gttagaagaa ataatagcag gagaagcaac agttttatct gttaatggaa aaattggagc
    17821 cgtcgtcatt actaaagaag atttgggatt agagaatgtt ctcacagaat taccctatgc
    17881 aagtgaagaa gatgacggca ttatcacggc agaaatgtat caaaaaattt taaacagtgg
    17941 agaaggtgac tacgtgttgc cagttgccac tatcgaccgt ttgggtggca taaaagttgg
    18001 tgaattattg acgattgatg agacagggaa agtctctgca gtcagacaat ctgatgtcaa
    18061 tttttcgctg gagttaaaag aaaaactcga ttcactgaaa aattatactg ctggagaaaa
    18121 catcactatt gatgaagatg gaacaattag ttctacaggt ggtagtggga ctggtggtgt
    18181 caatcagtca tatgtagatc aaaaattcca agaagctgta aatcaagcag aaaattacac
    18241 aaacgaaaga attccaaatt ttacttttga aaaaattggg gaggtataga gaatgacaga
    18301 tatcgtaaaa ataaaacaaa gcaatgtaca ggtttatcca caaactcatt ggaatgctat
    18361 agaaggcaaa ccaacaacgg tgaagggaga taaaggcgat cctggccaag cagcaacaat
    18421 taccatagga accgtttcta gtggttcaac cgcttctgtt acgaatgtag gaacatcatc
    18481 tgcagctaga tttaattttg ttttaccaaa gggagataaa ggtgatcctg gaataaatgc
    18541 cacaactaca gctgtagcta caactacagc aaatgggttg atgtcgtcca cagataaaac
    18601 taagttggat ggaattgcag ctggagcaca gaaaaatcca ggtaatgcta caactacgac
    18661 agcaggttta atgtcagcaa ctgacaaagc taaactcgat ggattagcca atattacatt
    18721 tgagaaagtg gggacggttt aatggctgat attgtgcaat taaaagaaga cggagttgct
    18781 aaatacttaa aaacgcatgt agaagctatt gatggtaaag aagcattggt gcagacagat
    18841 ggagaccaag ccattgcagg acataagaat ttttcaggtt ctgtaacaat caataataaa
    18901 cgtgttttga cgactgatga taacagatat gaagtggtaa atctggttgt cactaacggt
    18961 aatacaggga cagcaaagct ttatcgtgaa ggaaaaacag tttctatata ttttgtggct
    19021 ttaaacggaa aaagtagtgg cgggaatgat tcggttattt taactgttcc agaaggctat
    19081 cgg
//
LOCUS       DACBYO010000053        18564 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.053, whole genome shotgun sequence.
ACCESSION   DACBYO010000053 DACBYO010000000
VERSION     DACBYO010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.053"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            6..305
                     /locus_tag="IVD26_001807"
     CDS             6..305
                     /locus_tag="IVD26_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6079755.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="IVD26_001808"
     CDS             378..1739
                     /locus_tag="IVD26_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAP6079756.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="IVD26_001809"
     CDS             1761..2021
                     /locus_tag="IVD26_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079757.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="IVD26_001810"
     CDS             2035..2787
                     /locus_tag="IVD26_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAP6079758.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="IVD26_001811"
     CDS             complement(2881..3486)
                     /locus_tag="IVD26_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6079759.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="IVD26_001812"
     CDS             complement(3539..4513)
                     /locus_tag="IVD26_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAP6079760.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5670)
                     /locus_tag="IVD26_001813"
     CDS             complement(4891..5670)
                     /locus_tag="IVD26_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6079761.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IVD26_001814"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IVD26_001814"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP6079762.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="IVD26_001815"
     CDS             7161..8558
                     /locus_tag="IVD26_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP6079763.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="IVD26_001816"
     CDS             8639..9079
                     /locus_tag="IVD26_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP6079764.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="IVD26_001817"
     CDS             9227..9553
                     /locus_tag="IVD26_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP6079765.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="IVD26_001818"
     CDS             9554..10303
                     /locus_tag="IVD26_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079766.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="IVD26_001819"
     CDS             complement(10383..10838)
                     /locus_tag="IVD26_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP6079767.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="IVD26_001820"
     CDS             complement(11265..11540)
                     /locus_tag="IVD26_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079768.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="IVD26_001821"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="IVD26_001821"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAP6079769.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="IVD26_001822"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="IVD26_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP6079770.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="IVD26_001823"
     CDS             14770..17436
                     /locus_tag="IVD26_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP6079771.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="IVD26_001824"
     CDS             17800..18552
                     /locus_tag="IVD26_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6079772.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
BASE COUNT         5964 a         3212 c         3832 g         5556 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct tttt
//
LOCUS       DACBYO010000054        18533 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.054, whole genome shotgun sequence.
ACCESSION   DACBYO010000054 DACBYO010000000
VERSION     DACBYO010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.054"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(14..214)
                     /locus_tag="IVD26_001825"
     CDS             complement(14..214)
                     /locus_tag="IVD26_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP6079773.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(667..987)
                     /locus_tag="IVD26_001826"
     CDS             complement(667..987)
                     /locus_tag="IVD26_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079774.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(1490..2608)
                     /locus_tag="IVD26_001827"
     CDS             complement(1490..2608)
                     /locus_tag="IVD26_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079775.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            3079..4386
                     /locus_tag="IVD26_001828"
     CDS             3079..4386
                     /locus_tag="IVD26_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAP6079776.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            4507..5706
                     /locus_tag="IVD26_001829"
     CDS             4507..5706
                     /locus_tag="IVD26_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAP6079777.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(5733..7001)
                     /locus_tag="IVD26_001830"
     CDS             complement(5733..7001)
                     /locus_tag="IVD26_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAP6079778.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAAYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(7171..7812)
                     /locus_tag="IVD26_001831"
     CDS             complement(7171..7812)
                     /locus_tag="IVD26_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HAP6079779.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKK"
     gene            complement(8221..8724)
                     /locus_tag="IVD26_001832"
     CDS             complement(8221..8724)
                     /locus_tag="IVD26_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP6079780.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(8847..9611)
                     /locus_tag="IVD26_001833"
     CDS             complement(8847..9611)
                     /locus_tag="IVD26_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAP6079781.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            9719..9994
                     /locus_tag="IVD26_001834"
     CDS             9719..9994
                     /locus_tag="IVD26_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAP6079782.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            10554..11504
                     /gene="yidC"
                     /locus_tag="IVD26_001835"
     CDS             10554..11504
                     /gene="yidC"
                     /locus_tag="IVD26_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP6079783.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(11550..11951)
                     /locus_tag="IVD26_001836"
     CDS             complement(11550..11951)
                     /locus_tag="IVD26_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP6079784.1"
                     /translation="MSRQLVLISHGKFCEELKKSTEMIMGPQEDIYTLPLLPEDGTET
                     YKQKFLTVTDSLNDFVVLCDLLGGTPANIISKLIMEGQQITLYAGMNLPMVIEFINSQ
                     MIGSEPEFVRAGCESIVSVNELINGIAEEEE"
     gene            complement(11965..12774)
                     /locus_tag="IVD26_001837"
     CDS             complement(11965..12774)
                     /locus_tag="IVD26_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP6079785.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDNTPELKEMMKTHTQFFNTSNFFNTIITGIDLAMEEKEGIASKETVSGLKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPIGVFIWIFAQIVVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKILPAGIVGGVYWLLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            complement(12761..13651)
                     /locus_tag="IVD26_001838"
     CDS             complement(12761..13651)
                     /locus_tag="IVD26_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6079786.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLNAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDRHVEDMNYQAIERNFLMGALPWSLSRMIPVFLAL
                     AFGGGLVENVVSVLNGNLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHLSYLILGFT
                     ITALLATLFSNVQLLGTSVASVVKDLPATFNSLPMLAVALIGLALAMISYKNDQNKDH
                     QPLASEPSHSVEGEIEDDEI"
     gene            complement(13664..14143)
                     /locus_tag="IVD26_001839"
                     /pseudo
     CDS             complement(13664..14143)
                     /locus_tag="IVD26_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724290.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
     gene            complement(14319..15260)
                     /locus_tag="IVD26_001840"
     CDS             complement(14319..15260)
                     /locus_tag="IVD26_001840"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HAP6079787.1"
                     /translation="MITTVTLNPSIDIAYTIEELNLDKVNRVETVNKTAGGKGVNVAR
                     VLNLLGEEVIATGLIGGQHGEYLKNQLDQLGIMHQFVPIKGETRDSIAILHSSRQTEL
                     LERGPFITKKEQQTFTDHFEQLLEISDIMTISGSLPQGCPLDYYKQLVALADKKGKDI
                     LLDTSGKFLLEVLEGKEKPLLIKPNLEELGELIGQRICSSIQLEKIQSLLAHPIFEGV
                     PWVVVSLGERGAVAKVAQCFYEVIIPKISVVNPVGSGDATLAGSAHALSKRQSIEEIL
                     AFSMACGMANAQQEKTGWIDPMKVTMLMKHIQVKKIK"
     gene            complement(15257..16252)
                     /gene="lacD"
                     /locus_tag="IVD26_001841"
     CDS             complement(15257..16252)
                     /gene="lacD"
                     /locus_tag="IVD26_001841"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAP6079788.1"
                     /translation="MNEEKNRAMERLSTKDGIISALAIDQRGALKKMIKSLGKEPSED
                     QISEFKELVSAELTPYASAILLDPEYGLPAAKVRAKETGLLLAYEKTGYDATTPGRLP
                     DLLADWSSLRLKEQQADAVKFLLYYDVDEAPEINHLKHVFIERLGSECEGENRPFYLE
                     LVSYDAQISDSSSPEYAKVKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVNGYSTG
                     EFIHSKEEAAAFFKEQSEATPLPFIFLSGGVSTELFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGKDGAIHWLRTNGRENIETLNKVINETATPWFNKTKSKKVKMK"
     gene            complement(16245..17441)
                     /locus_tag="IVD26_001842"
     CDS             complement(16245..17441)
                     /locus_tag="IVD26_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6079789.1"
                     /translation="MFELSKNKLKQIGAAITTQEIKQQPDLWKETIDRLMQSQENLAL
                     FFDQIKKEANGRRIRVIFTGAGTSQYIGDTLLPYLNEHGDNQFFIFHSFGTTDIVASP
                     KEFLFPNEPTLLVSFARSGNSPESVAAVQIANEQVETLFHLTITCAKEGMLAKNAQDD
                     KQNYLLLMPERANDAGFAMTGSFTCMLLSALWIFDQTAMEKKERYLEQLVKIGQDLLS
                     RDQEIQKLLPDFFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVVGFVSNQPYTRNYDLDILEEIKEDRVTANVIAIAQPGTIDFSGMTVLLE
                     DSVSKLPDAYLALAMIMTAQIIALYTSIKVANKPDTPSPTGTVNRVVKGVIIHKYETE
                     GEMTDE"
     gene            complement(17459..18187)
                     /locus_tag="IVD26_001843"
     CDS             complement(17459..18187)
                     /locus_tag="IVD26_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6079790.1"
                     /translation="MESSNKGKSLYYQLVDLLKDRIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELENQGYIYRRHGKGTYVSDLSDKSSNLAGAYSFTEEMREIGRVPKTV
                     ILEFRQMEANKRIAKNLNIHLGETVFKLKRLRLADEEPLMVERSYLPAKLFMGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDAVVLRIADGAPVLHLTRITYNVKN
                     EIIEYTDSVARADQFHYKIRHIRK"
BASE COUNT         5571 a         3926 c         3159 g         5877 t
ORIGIN      
        1 tagtataggt taattaagct ttagtaacgt ttgttgcttg aggtccgcgt tggccttctt
       61 caacatcgaa agttactgct tggccttctt ctaaagtttt gaatccgtcg ccttggatag
      121 ctgagaaatg aacgaataca tcgtttccgt tttctgcagt gatgaatcca aatccttttt
      181 ctgagttaaa ccattttact gtacctgttt ccataataaa aatcctcctt gtgtatcaac
      241 acatattttg caattacttg aatggtgtat atctggaaga tgtttatttg aaacaagcta
      301 ccacagatta ccgaacaaaa actactccta tagtatatca taccgtttac aaaaaagcta
      361 gagtttttcg acttttttta ttaaaaaaag ttttctcagc gattacataa agtgaaaaac
      421 cgaacttttt tttaaaataa acgacatatt gttcagttgg tgtttttttg ctctgatgtt
      481 cttttttaaa ctaaaaaaat tattctttct gactacttat cggttctgtt tcaacggtcg
      541 aggctgggga agattcttta gtaggtctga tgttctcatg gtatttctga tagcctatga
      601 cagttaccag aagaacaagg caaaccaata cgaccaacga gattagtttt tcttttttgc
      661 tcatatctat acctcataaa taacaggatg atgtccatca tatttctgag tatgagtaaa
      721 agcaaaagct gcagctgtag aatgtaagaa atgccagcaa ctttcataat cacaggtcgg
      781 acagtaccaa aagtaaccaa atcttggctg caaagaccgt tcttctgttt caggaatcgc
      841 agaatcaaga tctggtgtct gtacataaac atttttgtac agacgtgtgc ctgtaatagg
      901 aaaccgctgt gtttcttcag caaaaactgg ctgacttgtt aaacttaggg atagagacag
      961 caaacaccat aacagtcttt ttttcataaa gacctcctta tcgataagtt tttcccaatt
     1021 aaaatcatat ctcaagaacg cccgttattc acattttgtt cataaatgat gttttttgta
     1081 tcataatcgt caaaaagagg tcgtgaccac gtcacaacct cttttttaaa cggtgttcca
     1141 gaagtagctt cttcggaaat aagccgaaat ttcacaaaaa tttgagaaat aatttttgtc
     1201 aatctcttct tatttcttga agctgaccac ttctgtcaca acctcttcct taaacggtgt
     1261 tcaaaagctt gcatctgcgg taataagccc accaaacaaa aaatatgaag agctattttt
     1321 gcttgctgtt cttattactt gatgcagaac agctttttca caacctctca tacacggtgt
     1381 ttaatcagct gaccttcggt attagctcaa aaaacggcaa aatatgtgaa actatttttc
     1441 cgtttgtttc tctaatactc aggtcaaaac actgatttca caacctcttt taataacgaa
     1501 gaatcgctgt cagactcttt tcatctggcg catctttttg atccaaaata aacacttttc
     1561 cgccattaat gatcacatca tctgctaatg cattcaacac ttgacgccga tcatattctg
     1621 tttcaggatc ttcaccgaaa ccatcagcta agtttgacgt agcgataaat aaatgtgaca
     1681 cttttccttc tttcgcagct ggaacgatat caactaactg atcgatgaat ttcttatcta
     1741 agagtttatt gtattctttt gattcttgag ctgcgagttc acttgacagc ttcttcgccc
     1801 cttcttcgat atctctaaag gatagctgcg caggagaagc agaaatcgca acgtctgcac
     1861 aataataggg atttttagca atttttttga acatcgtctg attttctggt agagcaaata
     1921 aataaatcgg ccattgttct ggattttcga aagaatcctt caagtacgta tcaactgctt
     1981 ggtaatagtt gacccaatcg atctctactt cttcatcttt tggatttacg ccatggaaag
     2041 ttactccatc tcgggctccg cctcctccat tagaagagaa gttcaaaccg ccacctgtca
     2101 gttcagatcc caatgcagta acgacatcaa ccggtgcccc ttctggtaga gatacttctt
     2161 ttacttgttt gttgctgact tcatacaatt tcatggagtc gcggttcaat cccaataaat
     2221 aataagaata gttgaactgc ccatttttga taatagccag taaataagga agatcactta
     2281 catagtattg atcgtctacc gggatactca aacgatggat ataggtttgg tcagcagtta
     2341 taatgaccgc tacactcgta gttgcactac gccaaaacga aggatctcct aacaaatttt
     2401 caattttttc ttggaacggg gaccagtcat gttcggaata ttttttctca aaacgtttct
     2461 ttgcttcttt cgcaaaattt ttgaatttga tctgatcttt ttccacatct tgatgggcga
     2521 catgcgtatt cagcatgatc gtgacgaatg gtcctttagc gccttctgaa gtcaattgtg
     2581 acaataattc tttatccttt tttgccataa acgtacccct cctaaaaaaa tcattccttt
     2641 gtttctatct aaagtctacc acaacactat ttttccatac aataaaacgt atctaaaaaa
     2701 ataaaacggt ttctacggtt ttaaatttag ctattttttt aagttatctt cataatttcc
     2761 tcaattattt agccccagtc ttcaactatt cttcatgaaa tgctgataaa ctaagaaaaa
     2821 gaataaaaga ggtggatctt atgcatttga ttatgatttt cagtttatta agtattatca
     2881 gtttatttgc tttcagcgct tcccgcttat tagatgcgga aacacagcct attcctgtaa
     2941 aagtacgtaa aaacgaccgc taaccttcca taacgtgcgt tcttatccta aagttttttc
     3001 agaaacattg aaactctctc ccctctctga taaaatttta atttgtagcg aaacaaatta
     3061 attacaagga gatcggatat gtccataaaa aaaacacgtc tagtcctatt attggctagt
     3121 ctcattcttt gccttgcttc ttttctacca gctgttgctg tgcaagctga agatactttc
     3181 aaagtaaatg caaaagcagc ctttgctgta gatgcgcaaa gcggtaagat tctttatgat
     3241 caagatggag aaaaaaccat ggggatcgct tcaatcacaa aaatcatcgg tctttacatc
     3301 gtccttgatc aagtaaaaga agggaaacta tcatgggatg ataaagtttc aatttcagat
     3361 tatgcagaaa atttgagtgt caccccagat ttatcaaatg ttcctttgca taaagaaaac
     3421 acctacaccg ttaaagaatt attcgactct gcaatcatcc agtcagccaa cgcttcaatg
     3481 gttgccttgg cagaaaaaat ctctggcagc gaagcaaaat tcactgaacg aatgaaagaa
     3541 caattgaaag attggggtat caaagatgca acgatcgtta atgcatcagg actgaataac
     3601 tcttatcttg gcgaaaaccg accagaaggt actggagaaa acgacgaaaa tcaaatgtct
     3661 gctcaagatg tggctatcgt tgcccgtcat ttgatcttgg attttccaga aatactggat
     3721 gtatctagca ctacgacaca aatgtttggc gaaaacacgc aatcaccagt agaaatggtc
     3781 aactggaact ggatgctccc aggattcgtg aattataaag aaggcgtgga cggattaaaa
     3841 actggtacga ctgaacttgc aggagcctgt ttcgtcggta cgatcactaa aaacgatcaa
     3901 cgaatcatca ctgtcgtatt gaatgcagac ggccatgcgg aaaacccaag tgcccgtttc
     3961 aatgaaacag ctcgcttaat ggattattgc tacgacaatt ggtcagaaaa agagcttgga
     4021 aaagccaatg caagtatccc tagtctaaaa accattgatg taaaagacgg aaaagaatca
     4081 acagtgcccg ttgtgcttaa aagtcctgta aaagtatggg tacggaacga tatggatact
     4141 ggaaaattaa caatcacacc aactcttgac aaaaaacaag tcactgacaa tgagatccaa
     4201 gcacctatgg ataaaggaac aaaaatcggt accgcaacga tcaccttggc agaagataaa
     4261 ttaggttatc ttgaagacaa caacgcgcca tccacagaaa tcatcacgga taaaaccgta
     4321 gaaaaagcaa atattttcgt tattggctgg cgacgcgtcg cagaattttt cggtaacttg
     4381 ttttaattga acaaaaagaa aaaagcatct ttccatgtgg aagatgtttt tttgcttttt
     4441 ctagtttaaa taacagcttt tttcatctat tttcgttata ctgtataaga aaaaggagtt
     4501 gaatttatga atctaaccag agatctgatt tttttggttc tctatcttat tggggtattc
     4561 tccatcgttt attggcgaaa acagaaaaag gatccttcct tgttctttta cagcagtaca
     4621 tggacgtttg cggtaatctt gacttatttt gtcgtgttgg aaatttttta ttcgaccttt
     4681 tattttttga ttcccttagt gtttttcagt atctttgcct tttcctattt ttcagaaaag
     4741 cgaaggctgt tgaatggtct tttattcaat attttcctca ttagttttgg tatctacttg
     4801 tttgtcttgc tatacgaaac acaaaatatt tttcttggcg gactgattgc cttgatcacg
     4861 atcccgttac tgcttgtctt tctattcggc atttatggat tgatcgtttt tcttttttgg
     4921 aacggtgtca cagttttacg tagagagtcg cattcattag ctaatctttt aacgttgata
     4981 ctagccattt ttcttacatt gtttcttgtt tttgactttt tcttgttaaa atatttacca
     5041 caatggataa atgctttgtt tttctgcatc ccattgatct tgatctatct atttatcgta
     5101 ttctacaact ttttgactgt ctcattcttg tatcagttca accgccctcg atacaaccaa
     5161 gacttcatcg ttgtgttagg cgccgggttg atcaatggag aaacagtttc tcctcttctt
     5221 gccaagcgaa tcaataaggc gattgctttt tattgggcac aaagccgtgc gacattaaat
     5281 ccgcctatcc tattaatgtc gggtggacag ggagcagacg aaaaagtacc agaagcaatg
     5341 gcgatgaaac aatatgccat ggaacaagga attcctgaaa gagatattct tgtcgaaacc
     5401 aattcgacaa ccactttgga gaatatgcgc tattcaaagg aaatcatgga tcagcaaatg
     5461 aaaggtccct atcgcgcgat cttcagttcc aacaattacc acattttcag agctggtctc
     5521 tatgcacgac aagcgaaact gaaggcaaat ggcattgggg caaaaacagc tttctattac
     5581 ttgcctaacg cgtttttaag agaatacatc gccatcttga tgatgaacaa aaaaagacat
     5641 atgatcattt gcggattgct tttcgcaggt tccgcattct tatcactgat cactttactt
     5701 ttctaaaaaa acaaggtgtg acaaaacata tgtcacacct tgtttttttc ttttattctc
     5761 ttgacgattg gcaagaatag tattcctttt ttgacggcta cttgctgtgc agaataaata
     5821 ccgctgtttc ctgaacacat aaagctgatc aagcagatca taaagaagta agcagcagct
     5881 tgtgaaccaa ataattcgat tcccatcaca aaacaggcaa tcggtgtatt tgtcgcacca
     5941 gaaaataccc cgataaaacc taatccagca agaaaaggaa cagaaacatg gagcaaaggc
     6001 gctagtactg cgccaagcgt tgcaccaatc tcaaatagtg gtgtcacttc tcccccttgg
     6061 taccccgcac ctaaagacaa gaccgtgaag aataatttcc caataaaatc ataagcatgt
     6121 gcctgtccat taaatgattc ctgcagtaac ggaagactca acccaaggta acgttgtgtt
     6181 tgcaaaatca acgctgcggc tacaactact gctccaccta tcgtatttcg ccaaacagga
     6241 tgaggaatcc attgcgcata ccgcgctttt aaaaagacga tcgaacggct gaatacccaa
     6301 ccaatcaaac caaaagcaat cccagcaaca aaaactttga agaacagcaa catactccat
     6361 tcaggaatca cacccatttg gtaatgtaga tgagaaacac catagctttc tgtcatgaaa
     6421 tttgcaaaaa gcgcagcaaa gaagctagga aatattgctt ctgttcggac tttaccgatt
     6481 gccaacactt ctaatccaaa taatgttcca gctaaaggtg tgccaaatac agaactaaaa
     6541 cccgcactga ttccactgat aaccaaaatc tcccgttctg ctttatccaa tcggaataaa
     6601 tgcgctatat tatcagctaa tgctcccccc atttgaactg ctgttccttc acgaccaaca
     6661 gatcccccaa ataaatgggt agtgatggtc ccaaacaagg tcaatggaat gagccgcaaa
     6721 gggatcttct cttctcctcc attcccttga tcgatcacta agttattccc acgactagaa
     6781 agaccgccat gatacgcata aagataagca aaaagcgcgc cgctgactgg caatagataa
     6841 agtagccaag gatgtgctag tcggatatct gtcacgaacg tcaggctatt taagaaaaaa
     6901 gcagacaagc tccccatgaa tactccgaga atcgctgtga ccaccagcca cttcaacatg
     6961 tacatcaaaa tacgcactgg actcggtaat tgtttttcca taaaaaattc ctcctcaaat
     7021 aaaaaaacgc ctactaaaga aaggggctgg ccccagactt tagtaggcgt cattagctat
     7081 cttacgttag catttaaagg cgaacaccat cacctattca cttccattaa aagatagcat
     7141 atttttctgt aaaaaacaat aaaattatcg ttatttcttt acacgttcag caaattcata
     7201 gaaaggagcc aatttcgtta actgttgatt acattgatca ctatcatgac aaatataatt
     7261 cccctttttc gtatacgtgc catcagaacc ggctttcgtt gtagaaagaa agagcgagac
     7321 attcgatgtt ttctgacaga tcgcacagat tcccttatta atcgttggtg ataaagtacc
     7381 gctgatccct tttaattttc catcttcgta ataaaccatg aatttttttt gcgtccctgg
     7441 atcattccaa ccgatgtacg tatgtgcttg caagtcgatt tcattccaag cgggttgttt
     7501 gagttttttc acttttcgga ataatttctc gatttgtggt ttgctcggct gcataaacgg
     7561 ctggacgatt tgcttcagct cctccaatgc tcgttctgct tgcgtttttg tcagttttac
     7621 atctaaaact gtcgttaaaa acgtatcgat ttctgatggt tcgtaaccta atacatcgcg
     7681 aatcttttca gctgctagag cctgaaccgt ttgtaccgtt tttgagtcat tgacagatga
     7741 gtacgcattt aataactgct ctacttctct ttttataaaa aaatattgat atggtttcat
     7801 tgtttgttcc atgattttaa agtcctttct tctaaccaaa gtgcatactt tgtagaaaaa
     7861 agtgatcttc tgcaaagtat gtgttacctg aagatcccgg actcttttaa ataagatacg
     7921 ttttgcatct tatcatcacc ccctttaatg ttcattcttc tatgtacatg attcattcga
     7981 taaataaaag taaaccgtat cttgagcaga tagtcaactg caaacagaaa aaggactgtg
     8041 acaaaagtcg tgtcaaagtc cctttctaca aacaaacggt gttccagaag tagcttcttc
     8101 aaaaaataag ccggaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat
     8161 ttcttgaagc tgacccactt ctgtcacaac ctcaatatgg tctattattg gttttacctg
     8221 ttaaatcgag gattcttttc cgaagtaacg ttgccatctc ttacgcatac ttgctgacat
     8281 aggctgagcg gcttctttga ctgcgcagta tttgtctacg aatgttacga tatatccttc
     8341 tttgtactta ggcggtgcaa tcgttgcgcc ccacatgtgc ttcaaaatga tatctcgctc
     8401 aagatccgac aaatcggtga tcttttctgc attctttaca gcgattcttg gatggatata
     8461 cgcatgtgtg ccttcatcaa atttcgtcgt acgccaatca tagtagaaca gatcatgcaa
     8521 aagtccagca cgcgctgttg ctttagcatt gccaccccat ttttttgcga gcagataact
     8581 atagtaagaa acactgatgg aatgctccaa acgagtggaa tgaacatgct gtgtgtaatt
     8641 cgctaatttt ttcactgctt ctgtttctaa aagatcttct acataagaca tatattcttc
     8701 gtcttcacgc catttttctg tcataattat cgatctgcca cctttttgaa tttcattttc
     8761 ttctgaaatt gatctaagta taccaccagt gttcggatta ttctagtcgc cttggataaa
     8821 atagccaaag cttaatagtt ccttaatcat aaagaaaaat gataaagaac aatccctgcc
     8881 gcaaccccaa cattcaacga ttccgcattt cctttcatcg ggatatatac gttctgatca
     8941 gtcaaagaca agatttcctg acttaccccc tgaccttcgt tccccatgat tattgcgaag
     9001 ttatctgatt tttctacttt gtctaaggcg tgtgcttctt catttaattc tgtgccatac
     9061 actgtaaacc ctttgtcttt cattaaagga atcacttctg tcaaatcttt ttgcaacaca
     9121 ggcaaatgat aattgcttcc ctgcatgctg cgcagcacct ttgtactata aatatctgcc
     9181 gttcctttgc ctaataaaac accagccata tcaaatgcat ctgccgtacg gatcatcgtc
     9241 cctacatttc caggatcttg tacattatct aataacagcc atcctcctga aaaatctggc
     9301 gtgccttcag ccgttaacgc catcactgct aagattcctt gtggtgtagg tagatccgat
     9361 acagcatcca tgacctcatc cgaaactaga aaagtagaaa tctctttgtt tgcggccagc
     9421 cagtctcccc attctttcat gcctcgctgt gtcacaaaaa gttcttttat ttctgcatca
     9481 gacgacgcag cttcttcaat cagatggaac ccttccaaaa gatattcttc cttttcttcc
     9541 cgatatttct ttttatgtag tttttttaat tctttgattc ttggattttt tgctgattgg
     9601 atctctttca cattcctcac ctccccatga ttatatcatg gaataggtgc ttgagcttgt
     9661 ttcatcctaa aaaaatcggt atcattaatt tataaaatag gaaagaaagg tgacgaacat
     9721 gcgcaaagtt aaaatgaacg tccaaggacg cgtccaaggc gtaggatttc gctacatgac
     9781 caagatggtc gctgatcaac taggcgtgac tggaacggta aaaaacgaag atgacggctc
     9841 agtcacgatc gaagcaatcg gcaatgacga catcatccag aaatttattg aagaagtcaa
     9901 gaaatctccg agcccaagtg gacgagtgca gtatgtggat gtccaagaag acccgatgat
     9961 tgaggaacga aagaaatttg atgtggtggg ataaggttgt gaaaaagctg gtctgcatca
    10021 agcattaagg acaggttgtg aaaaatagct ctccatattt ttcaacaggc tggacttaat
    10081 gccgtagatg caagcttttg aacaccgtca ataaggttgt gagaaagtcg cttagttttg
    10141 agtagtaagg agaattttgt gaaaatggct ttccacattt ttgcataaaa tttgacttaa
    10201 taccgagaaa ctgacttttg aacaccgtcg ataaggttgt ttttgagacg ctttgcctca
    10261 agtattaaag ataggtagta aaaaagctga tctataactt gcaataaatt tgcttaaccc
    10321 atattttcca gacagaacaa aaaagttttt agttttttaa ataagaaaga aacacttgga
    10381 atcactcttt tctttccaag tatttctttc ttgatttttt gtcttttttt caaaattttt
    10441 cgctacgtaa aagaacgaat atttatatga aatttctatg aagttgattg aattccatgc
    10501 gcttttttag tatagttaag tttgtgtaaa aattatagaa gaggaagtat tctatgaata
    10561 aatggaaaaa ctggttattg ggatccggac ttgtcagtat cctgctcttt ttatctggct
    10621 gtgtgcggat ggattcaaac ggaaaccctg acacttcggg aatcgtttat cgagtactcg
    10681 tccatcctat gggccaagcg attacatatc tagttgagaa tttcaattgg tcttatggct
    10741 gggcagttat tgcaatgact gtgatcgtcc gtatcatcat cttgccacta ggtattagtc
    10801 aatcgaaaaa aacaatgatc caatctgaaa aaatgcaagc gttaaaacca caagttgaag
    10861 cagcccaaca aaaattgaaa gctgcaacaa cacgtgaaga acaaatggca gcacaagcag
    10921 aaatgcagca agtataccgc gaaaacggat tgagtatgac cggcggaatc ggctgtctgc
    10981 ctctattgat ccaaatgccg atcttctctg ccttgtactt tacggcacgt tatacagaag
    11041 gtattcggga atcatctttc tacggcatcg atttaggctc accaagtatg gtacttgttg
    11101 tcattgcagg ggtcgcctat ctgcttcaag gatacatctc aacgatcggt attcctgaag
    11161 aacagaaaaa gacgatgcgt acgatgctaa tcgtctctcc tgctatgatc gtcttcatgt
    11221 cgatcagtgc gccagccggt gttacacttt actgggtagt cggtggtgtg ttcagctgtc
    11281 tgcaaacatt catcacaaac gttatgatga aaccacgttt gaaagcacaa gtggcagaag
    11341 agttgaaaca aaacccgcca aaacaagtcg tcactccaag aaaagacgtg acagaatcag
    11401 caaagccagc taacaacaaa caagcaacaa aacaaatcaa acaaccaaaa aacagtacaa
    11461 acaacaaagg ccgcaacgca ggaaagcagc agaagcggaa ataaaaacat aggacaaaaa
    11521 agatgagagc taagccctca tcttttttgt tactcttcct cttctgctat tccattaatt
    11581 aattcgttga cagagacaat gctttcacat cctgcacgaa caaactcggg ctctgaacca
    11641 atcatttgtg agttgataaa ttcaatgacc atcggaagat tcatcccagc ataaagagta
    11701 atctgttgtc cttccattat tagtttagaa atgatatttg caggtgtacc acctaaaaga
    11761 tcgcatagta ccacaaaatc atttaacgaa tctgtgacag tgagaaactt ttgtttgtat
    11821 gtttcagtgc catcttctgg taataaaggt aacgtgtaga tatcctcttg aggccccatg
    11881 atcatttctg tacttttttt caattcctca caaaattttc cgtgactaat caataccaat
    11941 tgtctactca tttttcgctc tcccttattt cgaaatcaca cccaatgcag ataaagcaac
    12001 acacacaatt aatacgataa aaatcgctcg agtaggagtc atgtttttct ttcctaataa
    12061 ccaataaaca ccaccgacga tcccagcagg taaaatttta ggtaagatca tatcgatata
    12121 gttttgcata ttcaatgtca catcgccaat cgttggtgcc catgaaaatt taacattgat
    12181 cattgtcgca actaatgccc ctaccatgaa tacccctaat aaagtggctg cgtccgttaa
    12241 tgcagttaag cgagattgca tagtagtaac taaggaaatt ccttctttgt atgcaaattc
    12301 aagttgcttc caacgaaaaa ccatgacaac gatctgagca aaaatccata taaacacacc
    12361 tatcggattt ccatcagttg ccatattcgc cgccaaagcc ccaaaaatcg ttggaatcaa
    12421 agcagcaaat acggaatctc caatcgctgc aaaggaaccc atcaatccag ctttcagccc
    12481 cgatacggtt tcctttgaag caattccctc tttttcttcc attgcaagat caatcccagt
    12541 aatgattgta ttaaaaaaat tagaagtatt aaaaaattgc gtatgtgttt tcatcatctc
    12601 ttttaattct ggtgtattgt ctccatatat ttttcttagt tgtggcaaga tagtatataa
    12661 atagccagaa ccctgcattc tctcatagtt ccaacctaat tgaaaagtga acaaacttct
    12721 tcgattgatt tgcttaaaat cttcttttgt taatttgtaa ttagatttcg tcatcttcga
    12781 tttccccctc aacagaatgt gatggctcac tagctaatgg ttgatggtct ttgttttgat
    12841 cattcttata actgatcatt gctagtgcta gaccaatcaa tgctacagca agcatcggca
    12901 gcgaattgaa agttgccgga agatctttaa caacgcttgc cacacttgtt cctaataatt
    12961 gaacattaga gaataacgtt gctaataatg ccgtgatcgt aaatcctaaa ataagataag
    13021 atagatgttt ttttactggt aaatagcgca gaagaatggc aaacccaaca gctggtaaaa
    13081 cagctcctgc tactgaaagt ccatcgccta gccattttag attcccgttt aaaacagaaa
    13141 caacattttc aactaatcca ccaccaaatg ctaaagctaa aaatacagga atcatacgag
    13201 agagcgacca aggtaaagct cccattaaga aattgcgttc gattgcttga taattcatgt
    13261 cttctacgtg acggtcaata cgatgggcaa agtatgtgtt agcgaatcta gctaaaatat
    13321 ccaattggat cattaagctt gctacaggca ctgcaatagc agcaatcgct tgttctggat
    13381 tcattccaag agaaatcgag aaggcagttg ctaaaatcgt cccagagttg gcatctattt
    13441 ttgatgcgcc tccaaacgtc cccactccta aaactgtcaa ctgcatactg ccaccaataa
    13501 tcaaacctgc gtttaaatca cccattacta aacctgcata taaccctgca aacactggcg
    13561 cactcattga agaatagatc tgtaattcat ctaaaatttg ataacctgca tataatgtta
    13621 ataataagat ctgccaccat tgaatatcca tggatcattc ctcctatttg attaaaagat
    13681 tcataaagtc ttctgcttta tcgtttggta ccatttgagc aattaaatgt ataccaagct
    13741 gatctaattt tttaaatact tcgatatctg catctaccac attgattgat tttgtaatgg
    13801 accgtgtttc attcgtttgt gacatattcc ccacatttac ttctttgata ggaactcctt
    13861 tttctactaa agataagatt cgatctggct tttttgctac gatcaatact cgttgagagt
    13921 catatttgcc agctaaaata tttgttgctg ctttttcgat tggcaaaatg cttaatttta
    13981 cccctgctgg agtcgctaac ttcaatccac ttttttcaat tgtgtttgtg gctacctcat
    14041 catccacgac catgattcga ctaatattca gtttcgttgt ccaaagattt gctacttatc
    14101 catgtatcaa acgtccatcg attcttacac caataattgc catcatgcat tctccttatc
    14161 tattttttct atttattgtt caattaaaac tgtgacatca tcaaatatcc cttctgtttc
    14221 aaagataacg ttttcatttt ttctttctta tatttcattt ttaagctaag aacaaattcc
    14281 ttcccaacta aagaaaacgc tttcttttat atttaagttc atttgatttt cttaacttga
    14341 atgtgtttca tcaacatcgt aactttcata gggtcgatcc agccagtttt ctcttgttgc
    14401 gcgtttgcca taccacaagc catagaaaat gcgagaatct cttcgattga ttgccttttt
    14461 gataacgcat gggccgatcc tgcaagggtc gcgtcacctg aaccaacagg attaacaact
    14521 gatattttag gaataatgac ttcgtaaaaa cactgagcaa cttttgccac agcacctctc
    14581 tctcctaaag aaacaacaac ccatggcact ccttcaaata ttggatgagc taataaggac
    14641 tgaatttttt ctaattgaat cgaagaacag atacgttggc caatcagttc tcctaattct
    14701 tccagattgg gcttgataag tagtggcttc tccttacctt ccaatacttc aagcaaaaat
    14761 ttaccagaag tatctagtaa tatgtctttc ccttttttat cagctaaagc aaccaattgc
    14821 ttatagtaat caagagggca tccttggggt aaactacctg agatcgtcat aatatctgat
    14881 atttcgagga gctgctcgaa atgatcggta aatgtctgtt gttctttctt tgttatgaag
    14941 gggcctcgtt ccaaaagctc tgtttgtctc gaactatgca ggatagcaat agaatccctt
    15001 gtctctcctt taattggaac aaactgatgc atgatcccta actgatctag ctggttcttt
    15061 agatattcac cgtgctggcc acctattaaa ccagtagcta tcacctcttc tcctaataaa
    15121 tttagaaccc tcgccacatt cactcctttt cctcccgctg ttttattgac tgtttcaact
    15181 cgattgactt tgtcgaggtt taattcttca attgtatacg cgatatcgat ggaaggattc
    15241 aaggtaactg tcgtaatcat ttcatcttca cctttttgct ttttgtttta ttgaaccaag
    15301 gggtagcggt ttcatttatt actttattta aagtctcgat gttttctctc ccatttgttc
    15361 ttaaccaatg aatagctccg tcttttccat tttcgacgta tgctttgacc ccatctttcc
    15421 atgtcgcacg tccacacaat acaccattga aggtggaacc cgattcatga gcaaaaatca
    15481 gtgtttgttg aaataattct gttgaaacac ccccactcaa aaaaatgaat ggtaatggag
    15541 tcgcttcact ttgctcctta aagaaggcag cagcctcttc tttgctgtga ataaattcac
    15601 ctgtggaata gccattcaca taattcatat tgactggtac ttctactttc aacacatcaa
    15661 ctttatattt tggatcagaa aattctttca tcatctcaat aactttgtgg ggcttgactt
    15721 tcgcatactc tggagaagaa ctatcgctta tttgtgcgtc ataagaaact aactccaaat
    15781 agaagggacg attttctcct tcgcactcac tacctaaacg ttcgatgaac acatgcttca
    15841 aatgattgat ttcgggtgct tcatcaacat cgtagtaaag taagaatttt actgcatccg
    15901 cttgctgttc tttcaatctg agagaagacc aatccgctaa taaatcaggt agacgaccag
    15961 gcgtagttgc gtcatagccg gttttctcat aagctaacaa taaccccgtc tcttttgctc
    16021 tgacttttgc tgctggcaat ccatattccg gatccaataa aatagcagaa gcatagggtg
    16081 tcagctcagc tgatactagt tctttgaatt cactgatttg gtcttcactt ggctcttttc
    16141 ccaacgattt gatcattttt tttagagcac cacgctgatc gatcgctaat gcactaataa
    16201 tcccatcttt tgttgatagt ctctccattg ccctattttt ttcttcattc atctgtcatt
    16261 tctccttcgg tttcatactt atgaataatg acgcccttga ctactcgatt gaccgtgcct
    16321 gttggagatg gtgtatctgg tttattagct actttgattg aagtatagag tgcaatgatt
    16381 tgtgcagtca taatcatcgc taatgcaaga taggcatcgg gcaatttact caccgagtct
    16441 tccaatagca cagtcatacc tgagaaatca atagtacccg gttgcgcaat cgcaatgaca
    16501 ttggcagtga cccgatcttc ttttatttcc tctaaaatat ctaagtcata atttcgcgta
    16561 tatggttgat tgctcacaaa acctacaacg agtgtctcgc tatttaaaaa agactttggt
    16621 ccatgacgaa accccatcga agaatcaaaa attgtagcaa ctttacctgc tgttaattct
    16681 aaaattttta attgtgcttc tcttgtcgca cctgccaaac ttcctgaacc cagataagcg
    16741 atccgttcaa aaaaatcagg taataacttt tgaatttctt gatctcttga aagaagatct
    16801 tgaccgattt taactaattg ttcaagatat ctttcttttt tctccattgc tgtttgatca
    16861 aagatccata aagcactcaa taacatacac gtaaaacttc ctgtcatagc aaaacctgca
    16921 tcgtttgctc tctctggcat caataacaga taattctgtt tatcatcctg tgcgtttttt
    16981 gccaacatcc cctctttagc acaagtaatc gtcaaatgaa acaatgtttc aacttgttca
    17041 tttgcaattt gcacagccgc tacactttct ggactgttgc cactgcgagc aaatgaaact
    17101 aataaagtcg gttcatttgg aaacaaaaat tcttttggtg aagctacaat atctgtcgtg
    17161 ccaaaactgt ggaagataaa aaactgattg tctccatgtt catttagata gggtaagagc
    17221 gtatccccaa tatattgaga cgttcctgca cccgtaaaaa taacacgtat tcttcttccg
    17281 tttgcttctt tttttatttg atcaaaaaat agagctaaat tttcttggct ttgcatcaat
    17341 ctatcgattg tttctttcca gagatctggt tgttgtttta tttcttgtgt cgtgattgct
    17401 gcacctattt gttttaattt gttcttcgat agctcaaaca tgttgttctc cctctcaatc
    17461 attttcggat atgccgaatt ttataatgaa actggtccgc tcttgctaca ctatctgtat
    17521 attcgataat ctcatttttc acgttatagg ttatcctcgt cagatgtaag acgggagcgc
    17581 catcagcgat tcgtagcaca acagcatctt ttttttgcac gatacttgca taaaactctt
    17641 catcagctaa ttgaacttgt tgttcataat cctgtgaaaa cacatcatac aacggtttac
    17701 tttcaagtaa cggcaaatca agtcccataa atagtttcgc cggtagataa gaacgctcaa
    17761 ccatcaatgg ctcttcatct gccaaacgca atcttttaag tttaaataca gtttcaccta
    17821 aatggatgtt caaattctta gcaattctct tattagcttc catttgtcta aattctaaaa
    17881 tgaccgtctt agggacgcgc cctatttcgc gcatttcttc tgtaaagcta tatgctccag
    17941 ctaagttcga tgacttatca gacaaatcag agacataggt accttttcca tgtcttcggt
    18001 aaatataacc ttgattttcc aattcctgta aagccagacg tacggtggta cgactcaccc
    18061 catagtgttg acaaagttct ctttcagata acagcttatc atgcggagtc atctgtgttt
    18121 cgatacgatc cttcaataaa tcaactagtt gataatacaa tgattttcct ttatttgagc
    18181 tctccataaa aatcacctct tctttactgg ttataaccac aacacaagaa tagtgaatta
    18241 ttaatcattt gtcaaaggtt ttttagacca aaaaagctat tataacagct ctttaaagct
    18301 ttatatcttg aatagacaaa gatacctcaa aaataccagt taccaataaa agaacagaaa
    18361 aaaagacgaa ccacataagc gatccgtcaa aatggtctaa cttatcgagc agcgtgatcc
    18421 acattaatcc ctatgatatt cctacaacta tcgttttatt acttccaata tcatttacaa
    18481 caactaaaaa tagcttatta atgacaaatg ttattattag ttttagataa ctt
//
LOCUS       DACBYO010000055        18189 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.055, whole genome shotgun sequence.
ACCESSION   DACBYO010000055 DACBYO010000000
VERSION     DACBYO010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18189
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.055"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(16..384)
                     /locus_tag="IVD26_001844"
     CDS             complement(16..384)
                     /locus_tag="IVD26_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAP6079791.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            555..1511
                     /locus_tag="IVD26_001845"
     CDS             555..1511
                     /locus_tag="IVD26_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP6079792.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            1584..1700
                     /locus_tag="IVD26_001846"
     CDS             1584..1700
                     /locus_tag="IVD26_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAP6079793.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(1755..3437)
                     /gene="recN"
                     /locus_tag="IVD26_001847"
     CDS             complement(1755..3437)
                     /gene="recN"
                     /locus_tag="IVD26_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAP6079794.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(3455..3904)
                     /locus_tag="IVD26_001848"
     CDS             complement(3455..3904)
                     /locus_tag="IVD26_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAP6079795.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            complement(4011..4829)
                     /locus_tag="IVD26_001849"
     CDS             complement(4011..4829)
                     /locus_tag="IVD26_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAP6079796.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(4838..5728)
                     /locus_tag="IVD26_001850"
     CDS             complement(4838..5728)
                     /locus_tag="IVD26_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAP6079797.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(5730..5954)
                     /locus_tag="IVD26_001851"
     CDS             complement(5730..5954)
                     /locus_tag="IVD26_001851"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAP6079798.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(5959..7296)
                     /locus_tag="IVD26_001852"
     CDS             complement(5959..7296)
                     /locus_tag="IVD26_001852"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAP6079799.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(7297..8151)
                     /locus_tag="IVD26_001853"
     CDS             complement(7297..8151)
                     /locus_tag="IVD26_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAP6079800.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            complement(8248..8697)
                     /gene="nusB"
                     /locus_tag="IVD26_001854"
     CDS             complement(8248..8697)
                     /gene="nusB"
                     /locus_tag="IVD26_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAP6079801.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            complement(8690..9115)
                     /locus_tag="IVD26_001855"
     CDS             complement(8690..9115)
                     /locus_tag="IVD26_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP6079802.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            complement(9361..10425)
                     /locus_tag="IVD26_001856"
     CDS             complement(9361..10425)
                     /locus_tag="IVD26_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAP6079803.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            complement(10597..10842)
                     /locus_tag="IVD26_001857"
     CDS             complement(10597..10842)
                     /locus_tag="IVD26_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP6079804.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            complement(10981..11355)
                     /locus_tag="IVD26_001858"
     CDS             complement(10981..11355)
                     /locus_tag="IVD26_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAP6079805.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            complement(11438..12352)
                     /locus_tag="IVD26_001859"
     CDS             complement(11438..12352)
                     /locus_tag="IVD26_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAP6079806.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            complement(12373..13176)
                     /locus_tag="IVD26_001860"
     CDS             complement(12373..13176)
                     /locus_tag="IVD26_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAP6079807.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            complement(13209..14198)
                     /gene="manX"
                     /locus_tag="IVD26_001861"
     CDS             complement(13209..14198)
                     /gene="manX"
                     /locus_tag="IVD26_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAP6079808.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            complement(14301..14792)
                     /locus_tag="IVD26_001862"
     CDS             complement(14301..14792)
                     /locus_tag="IVD26_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAP6079809.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            complement(14983..17817)
                     /locus_tag="IVD26_001863"
     CDS             complement(14983..17817)
                     /locus_tag="IVD26_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6079810.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
BASE COUNT         5230 a         4008 c         2995 g         5956 t
ORIGIN      
        1 gcttttctat ttttttcata ggtaagaaag tatgttcaca atgatcaaga cagcgtacaa
       61 gacgattgtc aacagaaaaa ccaaacgcca agtcatcttg aaataacgcg gataaataat
      121 ttcttcataa taatatgctt ggaaaacagc aatacaaatt cccattagca aaacagaaat
      181 aaagaaaaac ggtaagatag aaattgtccc tgtatttcta gacaatgcat gcataccgcc
      241 ccacaaaaaa ggaatcgcca aatcaggggc ttttatttta aaacgacgat ttaacgaaaa
      301 taattttaca agaaattggc aaccaaacaa aacgattacc gggtaaatat accaaaacaa
      361 gataagtggt gtgaatgtgc ccatgaacgt aaactccttt tttatcgttg cttcaagtat
      421 actgtatata ctttacacaa ctgtttcatt ttatttaaat ttatgcagtt atattctata
      481 tcttacaaac acattccatg tattccaatt ccctatccgt tataataaaa gaaacaggca
      541 acaggaggaa aatcatgatc aaatatttta cattagataa tgagaaactg cgtaataccg
      601 gaaaggaaac tgaccaaacg atctggtatt gtgtagaacg tcctaatcaa gaagagattc
      661 atcagctgac acatcaattt gaaattccgt cagattacat cacttccata ttggacgatg
      721 cagaaaattc ccgtacagaa gaattcaatc aatcaaagtt gacaaagcca gcgttattat
      781 tgttacaata tccttttgct aaaacaagtc ctagcggtta ttttcaagtg gatacatacc
      841 cgctctctat tattttgacg cccaaaaaga agcttatcac aattacgaat catgaaccac
      901 tgtttttaaa gaaagtcttt agccagacct ttccaaaaag tgatatttcg cctaatctca
      961 atatcttctt tcaattcatt tggcaggtca cactctctta caacagttat ttagctacgc
     1021 ttcaatctca atgcgatact ttggaagcca aacttcaagt atccactgaa aacaaacaac
     1081 tttatcaaat catggatatc caaaaaagcc tcgtttattt cagagaagcg acttctgcta
     1141 atttagatgc attgaaagaa ctagcgcaaa ataaactttt ccaagaaaat catgctttga
     1201 aaaatcattt acgtgatgta ttggtggaaa cagagcaggc aatgactact tctcgcattc
     1261 aattaaaact agtagaacaa atgaatcaga ctttttcagc aatcgtatcg aataatctga
     1321 ataatattat gaaaatttta acttctttaa cgattatttt aactataccg acaatcgtcg
     1381 gcagtatcta tggaatgaac attaagttac ctattgctga aagggatgat gcctttatat
     1441 ggctagttct attaacatta tttatttgta tcgtaactac ctattattta aaaaaaggga
     1501 agtttttata aaaaagccct cttgtggaaa tggaaaaaag attgtacact tgaatcaact
     1561 aattaatgac gaggttgaaa acaatgcgtg aaaaaaaaca aacaagtact tttgctaaag
     1621 taacaaaatt tgtcatttgg acaatgctga ttttaacgat tggatctgtt gtattgactg
     1681 ctgtaatgag tgtcatgtaa aaataaaata tagctatcag ctgctgaaaa ggacctgaac
     1741 cactgcgagg tggctcaggt cctttttgcg agtttcaata gttcttttgc atgttcgagt
     1801 gtgagttttg taatctcact tccagccagc atacgtgcaa tttcttcttc tctttctttt
     1861 gttttcaact ctgaaacaga agtttgcgta cgtccatcaa tcactgcttt cacaatataa
     1921 tattgatagt cggcgactgc agcaacttga ggcagatgag tgatgcacaa aacttgagag
     1981 tatttcgata tttgagaaat tttatctgcg atggcctgtg caactcttcc gctcacacct
     2041 gtatccactt catcaaaaat aatacttgtc acaccttgct cagaagaaaa aatagttttc
     2101 aaagcaagca acatccgaga cagttcgcca ccagaagcga ctttcaccaa aggcttcagt
     2161 ggctctcctg gattggtcgt aatgtaaaat tcgatttggt caaatccatc atgattcaat
     2221 tgtctatttt cttcttttaa gaaacgtacc tcaaactcag tgttttccat atacagactt
     2281 ttcaattcat gcagaatgga tttttccaat tcttttgcga tttttttacg cgcttcatga
     2341 agatctgcgg cttgttgctg aagtagaagc tctttttgct ctagttcctc tttcattttg
     2401 tccaattgac cttctgaaaa atcagaagaa gctagctctt cggtgatttc gtcatagtaa
     2461 gccaatattg actcaatgga ttcgccgtat ttacgtttca actgtcggat taattctaaa
     2521 cgttgcgtaa cttcttctaa acgactctca tctaactcca ataaatcaat ctgacgactc
     2581 atatcgccga ttgcatcttg cagcaaatag taagcacttt ggatattttc ataaattgct
     2641 tcatactcca catctagatg ggcgatccct tgcagttctg aaacggccaa gccaacacca
     2701 tctacactgt tttgttcatt attcgtcagt gctccgtaac ctgcagctaa tccatcagca
     2761 attttttgat aattgctaag tttttctctt tcttctttta atttctcttc ttctccgact
     2821 tgcaaatcag cagcagctat ttcttcttgc tggaaatgga gcatatctat tctctgaaca
     2881 taggattttt cattttgctg cacttttcgt accctttttt ccagctcacg ataagagata
     2941 tattcttgct gataactctt tttcttctgt tggaaagcta catctccaaa acgatccaat
     3001 aaagcaagat gtgattcagg ctggagcagt tcctgatgtt cgttttgtcc ttggatatct
     3061 actaaataac tgccgattct tctcagatta gctaatgtga taatatgacc attcactcga
     3121 caaacatttt ttccagttaa ggacatatcc cgtcgaacaa tcagattgtc ctcatctgtt
     3181 tcgatcccta attcaaccat cagttcagag aatccttctt gttttggtag ttcaaacaac
     3241 ccttcaagca cacatttttc tgctccttga cgtatataat cgcttgaacc tcttcctcct
     3301 gctaacagac ctaaagcatc gataataatg gatttacccg caccagtctc tccggtcagc
     3361 gcggtcattc cttcgtgaaa agaaagccgc aattccggaa taatcgcaaa gttagtaata
     3421 ctgatttctt gtagcatcac attcgctcct caacttaaag gtaatgcagg aagtctttct
     3481 tcaataaaac tgcctggtct tcagttcgtg taatcatcaa aacattatcg tcatcattga
     3541 taatcgaaaa taattctttc ttgtaacgtt tatcaatcaa atttgctgct gccgaagcat
     3601 ttcccggcaa tgttttcaaa ataacaaatt tttccatttg gtcaactgcc acgaaagcgt
     3661 cttttaatag tttttccaat ttagtattta catcttcgtt tgtttcagct ggtatgctat
     3721 aacggtagcc gccatctgaa gccggtacct tgatcagttt cagttccttt atatctctgg
     3781 aaatcgtagc ttgagtaaca gatattcctt tgcttttcag gatttcaaca aattcttcct
     3841 gctttcggat atcttgctca ctcaacaatc gagtaatcaa acgatgccga tctttttttc
     3901 tcattacgtc ttcgctcctt agcatattct tcttaatcaa tgatagctta tttccttggt
     3961 ataataaaga agaatccgca tacttctcac ttgattttca cagttacaat ttatttatgg
     4021 tcaaactgtt cgtgtgcatt tgaaaccact tctgccatat taatagctga attgattgtt
     4081 ccgctttcgg gtactttcct caagtgagcc aagaactcga tatttccttc tccccccgtg
     4141 atcggagaat aacttaattc cagcacatca tatccacctt gtgccgcaaa tgacaaaatg
     4201 tcttctaaaa ctttttgatg ggtctgaggg tcacgaacaa ttccgttttt ccctacagct
     4261 tctctgcctg cttcgaattg gggtttgatt aaagcaatca cttctccctc ttcttttaaa
     4321 atagcatgta atggaggcag catcagtttt agtgaaataa aagaaacatc gataacagca
     4381 acttctggaa ttcctaaggt aaagtcttcg ggttttgcat aacgaaaatt cactctttcc
     4441 attacgacga ctctaggatc ttgtcttatt ttccaagcta gctgattgta gccaacgtct
     4501 aaagcataac tcatttttgc gccattttgc aaagctgcat cagtaaatcc gccagtggat
     4561 gcaccaatat ctaacaatgt ttttccttca acagatagat caaatgcttt gagtgctttt
     4621 tctaatttta atccccctcg agaaacataa ggaagttttt tacctttgac tcttaattca
     4681 ctactcactg gaattttttc tcccggttta tcaaaccgct cgtttttttc gttgtaaatc
     4741 aaaccagcca tcactgaacg tttggcttgt tctcttgttt caaataatcc ttgtttgacc
     4801 gctaatacat ctacgcgttc tttttccatt ctttccctca tttctccaca tcaaattgct
     4861 tgatcatctg gcgcatcagc ccgccatcaa aagaaaaaac gtcctcttct aatttgtcta
     4921 tgatcttgtt ggcggataac agctcaatct ccaacgcctc acgtgtcttt tctaggccta
     4981 ataaacgcgg gtaagtattt ttttccatac gttcatcttt accagctgtt ttccctaatg
     5041 ttttcgttgt accaatcaca tcgagtagat catctcttat ctgaaaagct aaacctaaat
     5101 gttcggctaa tcgttgaagt agcaataaga tttcttcagg ttgcttcgct aatatgccac
     5161 cagccagcaa ggcataacga atcaaatgcc ctgtctttct ttcatgaata aatgctaatt
     5221 cttctaaaga aagctttttc gattcgccct cgatatctgc agcttgccca gcaaccatac
     5281 cttgtgatcc cgcacaaaca gctaattgct gaagcagcag aagcttagga gaattaccta
     5341 agtgtgccat actgattagc tggaatgctc ctgtaagcaa accatctccg gccaatatag
     5401 ctaatgcttc gccgaatact ttatgattgg taggttttcc tctacgaaga tcatcattgt
     5461 ccatcgcagg caaatcatcg tggatcaagg aatacgtatg caccatttct aaagcagctg
     5521 ctacttgata gacgggaaca tcaataggct catcaaagga agcaacggcc gttaaaagta
     5581 ataagggacg tattcttttc ccgcctgctt tcactgaata actcatcgca tcatagagtc
     5641 ctctatccgt tgtatgctca tctaaaaaag acaagatttc tttttctaca gcaggtagat
     5701 gaatagctga aaagtcagtt aatctcatct cagctttcct cgtttccgtc aaaatcaact
     5761 tcttcatttg attctgtcat cattttcgtc aaggtctctt ctgctttagc taatgtatct
     5821 tggcaatgtt tgcttaattc cattcctcgt ttaaacgaat ctagagctga ttctaatgga
     5881 acgtctcctt gttctaactg catgacaatt ttttctaatt cttgcagtga ctcttcaaaa
     5941 gttggatttt ccatattttt attctccttt gtctatctct tgtacttgtc ctttaacgat
     6001 tccatcttga taatggatcg tcagcaaatc cccttgatga atctcggtga cactttttac
     6061 tacttgatca tttaacgtcg tatagctgta gcctcttccc atgattttca atggactcaa
     6121 caaatcaaga gattgaacag cttgagcaaa acgctgctgc tgttgtttca tatattgttg
     6181 gattttctct tctaagcgtt tttctagata agcagtttct tggcgagctg ctttaactcg
     6241 ataaagcgga gccacttgtt ccaattggtg gcttaatgcg atcgtttgtt tttctttcgc
     6301 atgataaatt tgctgtgtag cttgatataa tcgctgtttc aactggtcta atttgatggt
     6361 ctgaccttca tacaatcttt caggctgccg aaatacatag gaacgtcgag cacgctcgaa
     6421 ccgttcttgt ttgcgctgga tctggcgtac aaacgcctgc tgcaatctag cttgccgttc
     6481 ttgaatgcgc atcaactctt ctgacaaaac aggaacagct aattctgcag ctgctgttgg
     6541 agtggcagcc cgaacatctg ctactaaatc agcgatcgtg gtatctgttt catgtcctac
     6601 agatgaaatc accggcgtat tagcttgata aatcgcccga gcaacccgct cttcattaaa
     6661 cggccataaa tcctcaatcg aaccaccccc acgaccgatg atcattgtat cgaaattgcc
     6721 catctcttct actctctgga tattcctgac aacattgtcc gctgcttggt ttccttgtac
     6781 aactgttggg aacaaaacca attggacaat tggatatctt cttttcaccg tcgtgatgat
     6841 atcgcggata accgctccgc ttggactggt aaggaccgcg attcgctttg ggaaacgtgg
     6901 cagcattttt ttaggccctt gaaaaaggcc ttccttcatc agcttttctt ttcgttcttc
     6961 caattcttga tataaagcac ctattccatc aggctccatg tgctctacat agatttgata
     7021 agaacctccc gcttcatata atgaaatacg cccaacgaca aggactttca ttccttcttt
     7081 tggctggaat cgtaattttt ggaatgctcc tttgaacata atagcagata tttttgcatg
     7141 gtcatctttt aagctgaaat attgatgggc attggcacgt aaacggaaat tcgatatttc
     7201 gcctgttaaa tatacgcgtt ctaaataagg atcggcatca aattttcttt tcaaatactt
     7261 cgttaatgta gtgacagtta aatattcttg tgccatctat tcacctgctc caaaagcttc
     7321 ggcagatttt acggtttgat acatcagcat cgtgatagtc attggcccta caccctttgg
     7381 cacaggagtg atccagcctg caataggctc cacttcatca aatttcacat caccgatcag
     7441 cttaccgtta gcatcacgat tcatccctac atctatcact acagcacctg gttttacgaa
     7501 ttcttttgtg acaaaatgtc cacgtcctat tgctacgact aaaatatctg cttcttgtgc
     7561 cagttcagcc agattttcgg ttttagaatg agcaacagta acagttgcat ctgccatcaa
     7621 gagtagctga gccatcggtt taccgacgat attgcttcgt ccgataacta ctgctcgttt
     7681 acccgccgga tcgatagaat aagcttcaaa cattttcatg atgccgtatg gagtacaagg
     7741 aatcttgtcc ggtttacccg caaggagtct gcctaaattc atcggatgaa aaccgtctac
     7801 gtctttttca gggcggatag ctaacaggat cttttcttca tctatatgct ttggcaatgg
     7861 taattggacc aatataccat gaaaactagg atcttgattg tatttttcaa tttctgcaag
     7921 tagttcgtct tcagaaatcg tctcaggata acgctctacc aatgaatgga ttccgatttc
     7981 ttttgctaca cgttctttat ttcttacata gatttggctg gctggatttt cccctaccaa
     8041 taaaacgact aatccgggat ggataccatt atctttcaat ttttggattt tttcagcaat
     8101 ctctgcctgc attttttcag ctaattcttt tccgttaatc aattctgcca tctaaccact
     8161 cccagatatt ttttgtgttt tcattctacc atagaatttt cccgatttat aacaggttta
     8221 tgatgattca tagaaaaaag ctaggactta cgccccagct tctaattctt tcaatacatt
     8281 ggataaaaca ccgttgacga atttacgtga acggtcatca ctaaatgttt ttgccaactc
     8341 gattgcttca tttaaagcaa cagccgctgg tacatctgtc acataagtca tttcaaaaat
     8401 cgcgatacgc aagatcacca aatccatttt tgagatccga ttgatgtgcc aattgttttt
     8461 taaatgtttt tcaatcactt tatccaattc atcttttttt gcacagacac cgccaactag
     8521 cgtatcaaga taaacaggaa caaactctga ttcatcttcg ttgatcatgt cgcggtggtc
     8581 taattcgatt gcgttgaaaa tcgcatcttc ttttgttagg tctgcattga agtctaatgg
     8641 aaataaagcc tgcaatgcca tttcccgaat ctcgtgtctt gataattctt tattcattct
     8701 cttcctcttc gtcttcaaaa agttcttcga ttgttggttg ttctaatttt tcaggaacaa
     8761 cagctactac atggatattg acttcagata aatcgatatc cgtcatgaaa aggacttgct
     8821 ggctgacccg ttcctgcatt tccattgcta ctttaggaac tgaaacacca tattctagat
     8881 aacagtaaag atctactttc aagccatctt cctcgtttgc taagtaaaca ccttttccgt
     8941 gagctgcacg tcctaataat tcagtgacat tgctggcaaa agttccgcgc attccgtata
     9001 cgccttctac tttagaagct gcaatcccga taattacttc gatgacttca ggagcgatca
     9061 cgatctctcc taaatcttgg tttgcgttta aaatcaaatt tttttcatct gccatttatt
     9121 tattcctccc tttgcctaag cacgagatac atccgaattc tctatgatgc ggcatagtga
     9181 tcacgtggta agaaaactgc cgccgatcag ctgcaaactg ctatgaattg gagaaaacac
     9241 ccaactttat tatctcttac agcttaaaag ttcttctata gtgtatcatt aaatcgagtg
     9301 attttctata acaaagtctg tgaacactga tttttacgct tacttcttct attgatgaaa
     9361 ctataagatg atcaattctt ttggtgaacg agtcaacaca cgatttccat cttctgtgat
     9421 caacaagtca tcctcaatac gtactccacc gattcctggt aagtagatcc ctggttcatc
     9481 agtgatcaca tttcctggta caaattgctt ttctgcacga gaagaaacgt ttggtccttc
     9541 gtggatctct aaaccgatcc catgtcctgt agaatgtcca aatgcttccc cgtaaccatg
     9601 ttttgaaata taatctctag caactgcatc taattggaca ccagtcattc ctggttttgc
     9661 agcatcaata actgctaatt gagcatctaa gactatttga taaatttctt ttaatttttc
     9721 cccaggatca ccaatagcga atgtacgtgt catatcggaa acgtaccctt cgtaatagca
     9781 accaaagtcc aatgtgatca agtcaccttg ttcgatgatt tttttgcttg ctacaccatg
     9841 cggcatagcc gaacgcaatc cgctagcaac gatcgtatca aaagaaacac ctgaagcgcc
     9901 aagagaacgc atataaaagt ctagttgatt tgcgacttca atctcagtca tgcccggttg
     9961 gatcattttc aggatgtgat catatgccat atccgcaata tgacatgctt tttcgataat
    10021 agcgatttct tcttcatctt tcacttctct gagttcttcg atcatctgtg aaacaggtac
    10081 taattccgca tcgatgattt cttctaaaac cgaatattct aaaaatgaga ctgttgtttc
    10141 ctcaaaagct aatgagtgca gttcttcttt gcgtactaag tttgctacct catcaaaaat
    10201 aggtccgaca tttttaataa tttcaaaccc ttgagcctgc gctgccgcct gctcggtata
    10261 acgaaaatca gtaataaaaa atgctttttc caaagtaata acagctaatc ctgtcgtacc
    10321 tgtaaagttc gttaagtaac gaagattgta cggactggta accaaaaatg aatccaaatt
    10381 ttcttcttgc atttttttgc gcaatttttc tacacgtagc atcataatga aactccctct
    10441 ttctttgcac gcttttttcc attatagcaa acttttcttc gtacacgaca gttaaataaa
    10501 aatttccgga aaacttcttt ttattttaaa taaataaagc caaaaaggag tcacagtctc
    10561 gctgcaactc cttttagttt actattttgt aaaaacttat gatcgttttc caaagaaaaa
    10621 tgagacaact gctaccaaaa tcactgcgcc taaaatagat ggaataagtg ccatacctgc
    10681 agcttttggt ccccattcgc cgaaaatcgc ttgtccaata cttgaaccga ctagtccagc
    10741 aatgatattc gttacacagc ccatcgaatt tcctttactg gtgatcgcac ctgcaattgc
    10801 tccgatcacg gctccaacaa tcaatgtcca taaccaactc ataatataac ctccttcttt
    10861 gctaatcaat tttagcatat gggatttaaa ggggacaaat aattggtttt gctatttcat
    10921 attttcttct gcaaagtaaa aaaataaaga aaacctcctc ttagaagttt tctttatttt
    10981 ttacttgcgt ttaaacatac tacgaatacc acgtttcact acatcaaaga aactcaatga
    11041 ttgtaccatt ctatcttcat ctacatattc tctgatcgca cgaagcactt ttttaggttc
    11101 tttggaagaa aatgtgtatg taccattttt tttcgtttga atggcatatc gaggaatcca
    11161 ttttcccttt agcatgactg atgctagtac ataatccact tcttcccatg gaatttggat
    11221 atatttgcgt ctatctcgcg catggtaaaa ctcaaaacca ttattaccta tcatgatttg
    11281 cccgtaatct gtcagacccg taaacgaagt agcatcaatt accaagtcta cttttgtatt
    11341 gattgattga accattttct ccctccagat atttgtttat gaacagtata ctatataaaa
    11401 aaagctcggg acaacgcccg agctatattt ttatggatta taaaagtccg atgacgtgtc
    11461 caacaacacc gactacgaat aaaccaagga tgataacgat tggagaaacc tttttcttaa
    11521 gcaaccacat acataacaat gttaatccta atgcagctaa accaggaatc aattggtcta
    11581 agttgtcttg taatgttgtt accttttcag gagaaagggc taagccatta ttaacttgtt
    11641 caaatgcact cttgattcct tcaccacctg aaggcaattt atcccattcg atgtaagcac
    11701 ctttatctaa ttttacagtt gatacaactg gtaagaattt gattgatacc catctttgta
    11761 caagggcagc taatacgaac atccctaaaa ttgaagcacc ttttgttacg tcttgtaaca
    11821 atccgccaga aaggtcatca gtaattttag aaccagcttt gtagccaaat tcttgtgtat
    11881 accacatgaa tgcccaacga ataatgttcc aacctaagaa gaagatgatt ggtccaagga
    11941 tatttcctcc catagctaat gaagcaccta gtgcacctag cattggacgt actgtaaacc
    12001 agaacactgg gtcaccaaca ccagctaaag gacccatcat acctacttta accccttgaa
    12061 tcgctacatc atcaacaggc gcgccattcg cacgttcttc ttccagagcc aatgtaaccc
    12121 ctaaaattgg agaagcaatg tatgggtgtg tattaaagaa ttccaagtga cgttttaatg
    12181 ctgcagaacg ttcttctttt gttttgtata attttttgat tgctggaatc atagaaaatg
    12241 cccagccacc gttttgcata cgttcgtagt tccatgaacc ttgaatgaag gtagagcgcc
    12301 acgcaacagc taaacgatct ttttttgata atttgatttt ttcttctgcc attttatttt
    12361 cctccttcaa gattaatagt cattcaaaat gtcgcctaaa gggtcaccag agttgcttcc
    12421 gcctccatta tttgatgaac cacccatttt agaaaggttc aagtaaataa gagctaatgc
    12481 aacacctaaa gcacctagag caatcaatgt taattgagaa attgcagcta caacgaaacc
    12541 aataacgaag aatggccata cttcttttgt agccatcatg ttgattacca aagcgtaacc
    12601 tacagctacg accattcccc caccgatagc cataccatct gttaaccatg ctggcattga
    12661 ttcaaggaat gattgcacag tttgtgctgg gataaatagc aacgctgctg ctgggaccgc
    12721 gatacgaacc ccttgtaaac atacagcaat gatgtgccac atttcaacct tacggatgtt
    12781 tccttcttca gcagccgcat ccatcaaatg aacgattgga acagcgattg tacgtacgat
    12841 cattgttaag aacaaccctg caacagccaa aggaacggca atcgcgatcg cagaaggaac
    12901 acctttaaca ccttgtccac ctaaaactaa aataattgct gatgctactg atgctaatgc
    12961 agcatctggt gctacagcgg caccgatatt tgcccaacct aaagcgatca tctgaagcgt
    13021 accgccaagt acgataccag cttcgaggtt accggtaact aaaccgatca atgtacatgc
    13081 cactagtggt tgatgaaatt gaaattcatc aagaatacct tccataccag ctagaaaggc
    13141 aactaatacg actaaaatta ttgaaataat agacatgata agcctcctat aaattttaat
    13201 attatttatt acgcttttgc taattcagct tttgcttttt tcaaaatatc atccatgtta
    13261 tcgcgtgaat cattaggtac tttacgtaca tcgaatttca cacctttttg ttcaagcttc
    13321 tcaaacgctt caacgtcttc ttgtcccata gacaatactt tacttacaac gactttaccg
    13381 accgaatgcg ccattgaccc aacatttaat tctttgatgt ctacgccacc ttcaacagct
    13441 gtcaatacgt cttcaggatt ttcaaataaa agcaatgctt tggtatttcc aaaacgaggg
    13501 tcttttgcta cttcgatcat tttgctaata ggaataacat ttgcttttac acctggagga
    13561 gcagcttgtt cgattagtct cttacgcaga tcatcctttg atactgcatc tgaaacaacg
    13621 ataatacggt ttggttgcac tgcttttgtc caagctgtcg caacttgtcc atgtaacaga
    13681 cgtgagtcaa cacgtgctaa tacatatttg atttttccgt ctccgaccac agttccttct
    13741 ggaagtgctc ctttaggttg tgcgtcttca actgctgctt tcggtgcttc tgccggttct
    13801 aattcttccg gttttacttt tacaccgtct tttgctgttt caatgatgtg tgctgcaatt
    13861 tcatgagcag attccattga aaagcgtgat gcgtaggctt caatcaacat tggtaaattc
    13921 aaaccgctga cgattgccca tttatctttg tgctcttcga ataatgtgtt tgattgattg
    13981 aacggtgttc cgccccataa atcaactaag aataacactt cgtcttgatt atcaaaagaa
    14041 gcaaccgctt cttccaattt ggctctcaag tcatctggac cttcacttgg tttcaaaatc
    14101 acggctttga cgttttcttg ttcgccaaag atcattgaac cggattgtaa gattccttca
    14161 gcaaattgtc catgacttgc taggataatc cctaccatat ttatacctcc tatttacttt
    14221 tgttgtaaca aattcaaaaa tattaataat tgctaaccat tacaacagaa ttatttgacc
    14281 ttttccaaca accattcttg ctacaccttt ttgattttcg ctagtagttc catcaaaagg
    14341 attttcctgt cagcaggtac ttttcgaatc tctaactcca cttcttgact gttcaagtaa
    14401 cgaaaggaat caatatcttg ttgatttact gaaacaaaat tggtaatcat tgatttgcct
    14461 tcagtaaaac tcataccgcc gatattcaac gacttcaact gtacaccgca gcggacaacc
    14521 gcttcaacat cttggggatt ggtgaataaa agcatcactt ttgctcgtga taataatcca
    14581 ctatgataga tttgaatcat tttctgcacg gttattacat ttgctgtgat ccccggcggt
    14641 gcagcttctt ttagtagaaa ctttctcaat ttatcttgag cgactacatc gctgatcaca
    14701 atgatacgtt caacacctgt ttgcttcgac caaactgttg cgacttgccc gtggattaaa
    14761 cgatcatcta tacgtgccaa tcgaatatcc atctgcaaaa ctccttcttc ctcactactt
    14821 cacagaaacc cctatcattt ctgtgtgaac aaccacctcc tagcacacac tactataagc
    14881 aaaaagcgtg ccaacttttt tacgatacac taattgaatt taaaggattc ttaaccaata
    14941 cacaaaaacg atacactata aaagtgtatc gtttttgtgt attcatggca cagtgtattc
    15001 ttttttatct aactgattat ggactagacg tagcagataa tacatttctt ctatcggcac
    15061 ttttactttt atctgatctt ccaacagaac aactgaggct gccaattggc tataaagagg
    15121 atcattcgtt gtatttgtca attcgttttc ttccacagtc aatggttcat tccgaataat
    15181 acgttcgatc attcctgctg tgtgcatcac taggttgatt ttgaatccat attcttcatc
    15241 gccgattccc gtcgtctgag agatttgtgt agaaaattgc cacattggat cgattaactt
    15301 actaccatta ataaagatga agttatcaga gataaactca acacacgtat ttttagctga
    15361 ctcttcatct agggagatga attcagtttc ctccaattct gattccatca gcaactgatc
    15421 caaaatgact tcgatatttt gatcaataaa acgttctaaa ggaataaatg gggcttggat
    15481 attcaaatca gtaatcccag tagtagctat gatctgatat tctttttgga taactggcag
    15541 ttcttctttc acttccacaa tcgacaaagc tagaacttct aattctgttt cttgacgctt
    15601 gtttaccgct cgttcgatca attctttgat tctttgtgct gtaccttcgc cagatgcgca
    15661 gatagccaaa acagcttttt tcttatgaat aggttttgct tcctgaacag attctacaga
    15721 agatatttct gcgtaacctc gaaaattttt caatgattca tgcaacatat ctagatctgt
    15781 ccctaatact gagacctttc gtacagtttc caaaactaga gaagttgtta ccatatcaac
    15841 agtacgtact ggaattccag tgtctctttg aatttgcgaa ttaaacgacg caagggaccc
    15901 catatctact aagagtatga ccccgcttcc ttcatctact tcttgtacat tgcgttcaat
    15961 tcggtccaat gctgttttcg gatccatatc caaaggcatg tctactgctc gtacgttctc
    16021 tgcatctaac aactgttgga caacttggac catactgctt gctgtgctgt ttccgtgagc
    16081 tgcaacgact acaccgattc tgccgcttgc ttgatttgcc cgtaacgaga cgagtagaac
    16141 ggtcaagtaa tagtcttcac tttctggaat ctccacttga aaatacgttt cgatataact
    16201 acgcacttct ttcgcaacag catattcatc tggaaaatca aaagccatct cacggatgtt
    16261 atcattcgta tgccgttctt ctcctaagtt gatttttttc aaaaaagaac tgatatgcaa
    16321 gctcatagca taaataaagt tttgctgaaa ctcatatggt aaagatcttt tgaccattac
    16381 ataaatctga ttggtcactt ctatgatttt cggatctaca aattctgcta atttgctgtc
    16441 tgcattaaaa gaaaaaccat ggtctttata gaaagacttc agatggatgt tgatatctgt
    16501 agaaatgaaa tgattgattg cttcttgatc caaaccatcc gacttcagta aagctgcttt
    16561 atctccgatg atatcatata gattataagg taactcatag gagtccgatt ggattttcat
    16621 gatcgtatca tttggtgcta cagttatctt tggctccaat attttagaaa gctctgccat
    16681 tgcactgcgg ttgcttgcta attgaatcaa tccgctacga atcccttctg tcaaatcatc
    16741 gattgtgatc gagatttcgg gtgattgcat atgatttaga aatcctcgtg cacatactaa
    16801 ctggatattt gacttcaatt gtcctatatt tccataggtc acactgccga tcaatgcttt
    16861 tgctacatct tctgtcaaag aaatctttcg ctgcgtgcgg tttgcttcgt gggcaatcat
    16921 gatttttact aaatcgactt tctcatttgc aggacgtttt tcaaaagccg gaagtttgat
    16981 attgattggg atacgccgaa caaaagtttc taatagagaa gaacctgggt cttctgtggt
    17041 cgcacctacg atccgtacat ttgcttcatg ggatttcgtt gtttccccaa gacgactgta
    17101 agttccatga tccataaagt aaaagatcat ttcttgacct tcaggcggca accggtgaat
    17161 ctcatccaaa aacagcatac cgccatccgc ttgatcgata atccccattt tttcttcatc
    17221 tgcgcctgta aaagcacctt ttgcgtaccc aaataaatga ctcatcaaaa gctcagggtt
    17281 attggcataa tcagcacaat tgaaaacaat cagttccgtt tcctcatcta ttacatgatg
    17341 cgcttttgca aaatgataca tcgcgtgtgc aaaataagtc tttcctgatc cggtaggtcc
    17401 tgtaatcaaa caatttaatc ctcttggcgg atacaaaatc gcagcttttg cctgttccac
    17461 tgaatttttc atgctgccgt tagctccaat gatttttgca aagatatcct tagtatctat
    17521 ttggagtgta tttttttctt cagagaccgg cgtttctttg taactgacta catgttttgt
    17581 aactggcttt acgtgcgtaa cgagtgtttg atatatgtaa cgtactggtc gtccgtctgt
    17641 ctttatcagt tttccttcgc gcactagctg attcagatct ttactgctat ttgttcgctg
    17701 aatccctaac acttcagcaa tttcctgtgt tgttactcct tgatcatatt ctgcctttgt
    17761 taaatgagcg gttttttctt tgacatacat ataaattcgg tcaatgcgtt ttgccaatgg
    17821 tatcgctcct tttctataga ctattgtact taggcttcaa aacataatac tatgtattta
    17881 tttctgtttc gtcaactatt tacctgattt tgttttgttg ataacacgcg gatagataga
    17941 aatgttcaat ttaaaagaac gaaaaatccc gatacgattt ttataatgga aacaagaaaa
    18001 agaacactgt ttaccatata attatttcac tgatagcaaa caatatagct tccatcaatt
    18061 gaaaacgata gttatcaaaa catcctgatt ccaaattggc aaaaaaatat taagtgtaaa
    18121 aagacaaagt aaacttcgta gcctccacta caacttttat ttttataaac aaaaaaggct
    18181 gtgacaaaa
//
LOCUS       DACBYO010000056        18010 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.056, whole genome shotgun sequence.
ACCESSION   DACBYO010000056 DACBYO010000000
VERSION     DACBYO010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18010
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.056"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(161..445)
                     /locus_tag="IVD26_001864"
     CDS             complement(161..445)
                     /locus_tag="IVD26_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079811.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="IVD26_001865"
     CDS             complement(463..1353)
                     /locus_tag="IVD26_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAP6079812.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="IVD26_001866"
     CDS             complement(1373..1591)
                     /locus_tag="IVD26_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079813.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3241)
                     /locus_tag="IVD26_001867"
                     /pseudo
     CDS             complement(1561..3241)
                     /locus_tag="IVD26_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
     gene            3508..4281
                     /locus_tag="IVD26_001868"
     CDS             3508..4281
                     /locus_tag="IVD26_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079814.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4362..4931)
                     /gene="thiT"
                     /locus_tag="IVD26_001869"
     CDS             complement(4362..4931)
                     /gene="thiT"
                     /locus_tag="IVD26_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAP6079815.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(4997..5099)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5105..6076)
                     /locus_tag="IVD26_001870"
     CDS             complement(5105..6076)
                     /locus_tag="IVD26_001870"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAP6079816.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6170..7543)
                     /gene="glmU"
                     /locus_tag="IVD26_001871"
     CDS             complement(6170..7543)
                     /gene="glmU"
                     /locus_tag="IVD26_001871"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAP6079817.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8046..8864)
                     /gene="purR"
                     /locus_tag="IVD26_001872"
     CDS             complement(8046..8864)
                     /gene="purR"
                     /locus_tag="IVD26_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAP6079818.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9031..9855)
                     /locus_tag="IVD26_001873"
     CDS             complement(9031..9855)
                     /locus_tag="IVD26_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP6079819.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9828..10508)
                     /locus_tag="IVD26_001874"
     CDS             complement(9828..10508)
                     /locus_tag="IVD26_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP6079820.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10531..11469)
                     /locus_tag="IVD26_001875"
     CDS             complement(10531..11469)
                     /locus_tag="IVD26_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAP6079821.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11714..12565)
                     /locus_tag="IVD26_001876"
     CDS             complement(11714..12565)
                     /locus_tag="IVD26_001876"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAP6079822.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(12719..15292)
                     /gene="mprF"
                     /locus_tag="IVD26_001877"
     CDS             complement(12719..15292)
                     /gene="mprF"
                     /locus_tag="IVD26_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAP6079823.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15433..16239
                     /gene="proC"
                     /locus_tag="IVD26_001878"
     CDS             15433..16239
                     /gene="proC"
                     /locus_tag="IVD26_001878"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAP6079824.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16318..17874)
                     /gene="rny"
                     /locus_tag="IVD26_001879"
     CDS             complement(16318..17874)
                     /gene="rny"
                     /locus_tag="IVD26_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAP6079825.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
BASE COUNT         5186 a         3885 c         3095 g         5844 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc ttttttcata tctccttgta
     2701 aaatcaatgc gccgttcaac gcacctaccg aggtacctgt gataatctca aagttgatat
     2761 catgttcctt cagcgcctgc cacacaccaa tctgataagc accgtgcgct cctcctccac
     2821 ctaaaacaag tgctgtatga tagaccagct ttttatttaa ttgtgtggtt ccttgatagc
     2881 cgtttttatg aaaaatacgc aaccattctt ctgatagagg agattgaaat aaaaaacaac
     2941 agttttcttt aataaaaaaa cgagcgcaag cttccatata ccgaaaaaat tttttccatt
     3001 caaaagtttc accttcaatc aacagattat taaaaataac atctcctcta cttttagcaa
     3061 tagtaaaata gacggtatat tttttcgata ctgctttaaa agcacattgc ttttttgcag
     3121 aacgccaaaa agcgtctcta ctttcttgat gactttgaaa aaatggaagg ggttgttttg
     3181 cttgctggat aggcgaatac agcgacattt tctgtgaaaa gtaaactttt tttatctcca
     3241 tcgcgctctc ctttttcttc aagtatacca gtacgtcata aaaaggtcat gagtctcgta
     3301 ttcgactttg tagattccat aagaaaacaa ttcataaaac ctcctttaaa taaaaaaata
     3361 caaaaatcac aaaaattaat tgaaaatgag agtgttttca atgaaaacgt gattttgtaa
     3421 tggaatttta aaataaaaga aacaagcttt tttaatgcaa atgttgtaaa ataaaagaga
     3481 ttaagaggaa ataagaggag gaacatgatg actgagtcag tttatgtaca tattgatacc
     3541 acaagtaatg ctgttttaac aaaagggctg actgctactg actttgcaaa cagtatcgtg
     3601 cattttcctc aaaacttgct cttgcttgat ccatctgctt ctgctggaga atatgaatcc
     3661 catacagggc tgaaagtaat ccgtggtaca gaaaatattc agcgtttctt ttcctcttct
     3721 cgtaacaggc gtggattcga tgaattgaag tggatcgact ttactgattt aacgatgctg
     3781 aaagaattga cacctttaga aatttcagaa ttattatatt ttggtcatat gaaaacacat
     3841 cttcattcgc cgttttttta taaactacag aataattttg tatacttcga tcttaatgat
     3901 cagctgaatc ggatttatta tcgctattta gatgaatttt ataggatttt tgctagtaaa
     3961 ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat cttttttcaa aaaagaaaca
     4021 cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc gtaatttgat gcaggaaggg
     4081 atcatttttt cttttgatca agttggtttg atcgatggta aatatcgtat cccaatctat
     4141 gtgattgaag attatatttg gaaattaaaa ggcacccggt atcgagaaga ggaaatcatc
     4201 gctactttaa tctactctgt caccgatcga cactggcaat tggtagaaga tgccgatctt
     4261 tcttatctgc cattgaagta gatctatttc ttatcaaaaa ataaaaagga aacaagaaac
     4321 taggacatga ttctgtctca agtttcttgc ttctttttta tttacagctc ctgtcgttta
     4381 tctggcacaa aaatcgaagg agtcgtttgt tggatcccta ataaaacgat gatcgttaca
     4441 atagctgtac tcaacccgct ggcaccattc attacgaaag aaaagagcca aggattcatc
     4501 ccccatagtg catacgctcc ccagaaaacc actcctgcaa taaaatgcca aaaatatctg
     4561 gaaagtgcgc caatcaatgc accaaacacg atgctttttc taatttgttt cgtattatcg
     4621 tctacatagc ctttttggac atttgaagcc atgagccctg ctgcgcctgc aaaagtatag
     4681 gcaatcgggt actcaatcaa cacttgaacg acacttaaat aataaacttg tcccaacgga
     4741 aaatgtagga tgccccaaat gaaacctgcc agcatccctg cctttgtccc tcttcttaac
     4801 gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa aactgctgcc gatctggatc
     4861 ggaatcaacg acaacaccat cgctaacgct gcaacaatcg ttccttctac ccaaactcta
     4921 ttttttccca taaaaaaact tcctcctttg aataaaaaag tcacaaagga ggaagcagct
     4981 ttcgaaaata gtcaaacagc tgtttattca caattcctac gctcgcataa ccgatacagg
     5041 tacgaagggt ttagaaatag attcaatctc agcccaattg gactcccctt tgtgagttta
     5101 tttattattt attttttgtt tcaaacaatg gactaactgg tttgttttca tggatacgtt
     5161 tgattgcatc tcccattagt ccgccaacac ttacttcatc gattttgtcg attttacgat
     5221 cttctggaag atagatcgag tctgtaacaa ctagacgctc gatagctgaa tcttctattc
     5281 tttgtaaagc agggccggat aatactggat gtgtacatga agcatacaca ctagttgcac
     5341 cagcttcttt caaagcattg gcagccaatg tgatcgtacc tgctgtatcg atcatatcat
     5401 cgatcagtac acaagttttg cctttgactt gtccaatgat attcattact tctgcaacat
     5461 ttgcttttgg acggcgtttg tctatgatcg caatcggaga tttcaaaaat tccgctaatt
     5521 tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac gacaacatca tcgcctttga
     5581 ttcctttttc taagaaataa ttggcaataa gtggcgcacc catcaaatga tcgactggaa
     5641 tatcaaagaa accttggatt tgaactgcat gaaggtccaa agtcagcatt cttgttgcac
     5701 cagctttttg aatcatgttt gctactaatt tcgctgtgat tggttcccgt gcacgtgctt
     5761 tacggtcttg acgcgcatag ccataataag gcatgactac gttgattgtt tttgcacttg
     5821 ctcgtttcag tgcgtcaatc atgatcagca actccatcaa gttatcattg actgggctgc
     5881 tcgttgattg aataacatag acatgcgatc cacgaatact ttcttcaatg tttacttgaa
     5941 tttctccatc actaaattga gtaacagatg attttcctaa ctcgacgccg actgctgctg
     6001 caattttctc tgctaatggg cgattggaat ttaacgcaaa aatttttaat cttgggtcaa
     6061 agtaatgttt tgacatgggg acctccactt tctttttcac aactctagaa ttctacctaa
     6121 taaatagtag tcatattttt taaataaatc aagtgatttt gcaaaagtct tagtttagat
     6181 aagggagttt ttttgcatat ccttctttat tgacttgtct tgctctcgca attgccagcg
     6241 catattctgg aatattgtct gtaattgttg acccggcagc aatcgaactg tttttagcta
     6301 cctcgacagg tccgatgata ttcgtgctag aaccaataaa gctgtggtcg ccgacagtcg
     6361 tatgatgttt gttctttcca tcatagttga cgaagacaac accacatccg acattgattt
     6421 cttctcccag cgtagcatca ccaacataag tcaagtgacc gactttagtt cctttgccga
     6481 tttgagcatt tttcacttcc acaaagtttc cgatatggac gttttcgcca atttcagctt
     6541 ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt cttgacatgg ctgctttcaa
     6601 tgactgagtt ttcaatgacg acgtgatcct caatcctact gtctacgatt tttgaatgtg
     6661 acccgatgac acaatcagaa ccaatgactg tatttccttg gatttgtaca cctgcttcga
     6721 tcaatgtgtc tggaccgatt tctacgcctg catcgatgta tgtcgttgct gaatcgacaa
     6781 agcttacgcc attgaccata tgcatctggt taattcgctt tctcatgatc tcatttgctt
     6841 tagctaacgc gatccgatca ttgactccca ttgattcttc aaaatcatcc gtttgataag
     6901 cagcaactgt atggccttct tcttttaaga tttcgatgat atctgttaga tagtattcac
     6961 cttgagcatt gtttgttcca actttgctta acgcatcgaa caaagcttcg ttgtcaaaac
     7021 agtaagttcc tgtattgatt tcttgtacaa gagcttcttc tggtgttgca tctttttgtt
     7081 ccacgatttt ttctacgatc ccaatatggt cacggatgat tcgtccatat cctgttgggt
     7141 tttctgcttg tgccgtcaag atcgttgcac ttgcattttt tccttggtga tattcaaaaa
     7201 gattgttcag cgtttcagta gtcaataatg gtgtatcgcc actgataact aacgttgttc
     7261 ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc atgtcctgtt cccaattgtt
     7321 ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc tttaacttgt tctgctccgt
     7381 gtccaacgat cgtaatcact tcatctggtt tcgtttcact gacccgatta atgatatgtt
     7441 ctaccatagg tttaccagaa acgggatgta aaactttata taattttgac ttcatgcggg
     7501 tacctttccc tgccgccaaa ataattgcat aacgtgcgtc caactgcgtc actcctaaat
     7561 atagtttgct gatttcagtt tatcccagta tacccatttt ttcaacaaaa caagtgattt
     7621 tcttttatcc cagcgttttc tggataaaaa aatagataga ccataacggg cctatctatt
     7681 tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt cacactactc ataaaacatg
     7741 aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt aaacggtagg cttacaacct
     7801 cttcattaaa cgtttttcaa tcagctgacc ttcggtatta gctcaataaa cggcaaaata
     7861 tgaggagcaa tttttccgtt tattgagcta atactcagga caggacgctg atttcacaac
     7921 ctctagataa acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgaaaaaa
     7981 tgtggaaagc cattttcaca aaatttttct tactactcga aactaagcag ctttttcaca
     8041 acctcttatt ctgaaaaata atttcctggc acaaccgtaa tatttttcgt ttgagtatct
     8101 acatctttga cataaagcag tgacgtataa tcatcgatgg cgcgatgacc gttgaatttt
     8161 gattcggcaa atacagtgat gccaacaagt tctgattcga attcttcaat caagctcttc
     8221 attccgttga ctgttccgcc gcctttcatg aaatcatcca ctacaaggac acgtgaacca
     8281 cgtttcaaac ttctcttaga cagttccatc ttttcaattc tttcagaaga tccagacaca
     8341 tagttgacac ttactgttga tccttctgtt atttttgagt cccggcgtac aataacgaat
     8401 ggcgcattca gataatagga cacagcttgg gcaataggta cgccttttgt ggctacagtc
     8461 attacagcat cgattttttc accaaggtat ttagaagcaa tgattcttcc aacttgacgc
     8521 agcagttcag gttctcctaa caaatcagag agataaacat atcctcctgg aagcagacgg
     8581 tcttgttctg atagacgttc tgctagagat tcaatatatt ttttcgcctc ttcatatgaa
     8641 atttcaggga tgaacaatac accacctgca gcacccggga ttgtttccaa ggttccatac
     8701 cctcgttctt taaatgtttt cttgatgatt cccaaatctt cactgataga agatttagca
     8761 gattcataac gttcggcaaa gcttgttaag gaaatcaatt catgcgggtg attcaataaa
     8821 tactgtgtca tgtcaactag acgttcactg cgacgtactt tcacctattc caactccttt
     8881 taagaaattt tatcgtttta cattatataa gtttttcttc aaaaattcga gcattttatg
     8941 aaaaaataag aaaatagttc ggtatttatt aaaataaaaa gaagcctata aaaaattttt
     9001 cgtttttata aggcttcttt tctttataat ttagttattt tttcttctga aggcaaccaa
     9061 tattcgtttg atgatattta caatcaggaa caaagcaata aagactaatg tgattgttgc
     9121 tcctggaggt gtatctagat aaaacgagct agttagtcct gacagcatcc ctagaaatcc
     9181 tacacaaaca ctgatagcaa tcacgacatt gaagcttttg cctaatcgca taccgattgc
     9241 tgcgggaaga accatgattg cggatatcaa aagtgcaccg gcaatcggga tcatcacagc
     9301 aatagccaca ccagtaatca cattgaacat catcgacatc aaatgaacgg gtagcccatc
     9361 cacgtgggcg gtatcttcat caaaagtcag aacatacatc ggccgtttga ataaaaagaa
     9421 caatataccg atggcaacga ataagattcc taaaaagatg acttgctccc atgtaatggt
     9481 cacgatcgaa ccaaacagat aggattggat acttgttgct gaattccctc cgctcaaatt
     9541 catcaatact aacgctagcg ccaaaccacc agccattaaa atggcaatgg agatttctga
     9601 ataggttcgg tagatcgttc gcagatactc caatatcaca gctgctaata caacgactag
     9661 catggtcgta agtgtaggat taaggttcaa aaagaatcct aacgctaccc ctgctaaaga
     9721 gacatgagaa agcgtatcag ccatcagcga ttgtcttctg atcactaaaa acacacctag
     9781 catcggggcg attccggcaa tgaagatagc ggcaagaaac gctcttctca tgaattcata
     9841 tgaaagcaac gccattgaga atcctccttt ctcaccagtc ggatctgtct gtccgcatac
     9901 tgtttgatat cttcatgatc atgggtgatc attagaactg atttcccatg gacatgcgca
     9961 ctatgtcgga gaagacgata aaattcattt ctggattctt catccatacc tgttgttggt
    10021 tcatcaagaa caaataagtc agggtcagta gcaaaaatac gcgctaaact gattcgctgc
    10081 ttttgtccgc cagacaattc acctattcgc cgatttcgca tatcccacat ccctacagct
    10141 tctaaagcac gctgtacatg ttgatgatct ttttcagaga gacgcttgaa ccagcggcct
    10201 cttggatatc ttcctgaacg gactaattcg atcaccgtac taggaaaacc tgcattgaaa
    10261 gatgcaactt gttgaggaat ataaccgata cttaattttt ttccttcttg atttttctca
    10321 gcaatcttta tcattccttt tgaaggtttc agtaatccta acgatgcttt caccaaggtt
    10381 gacttggctg ctccattttc tccagttaaa atgacaaatt cacccgcatc tacatgataa
    10441 gagacatctt ctagtacagg ttcatcatca tagtaaaagg tcaaatcaga tatttcgata
    10501 taacgcacct tacaacctcc attctaaaac ttaattgata ctttctttta aagctttcag
    10561 atttttttcc atgacagaaa tataattttc gcctgctttg atttgttcat tagtcaagct
    10621 ttctaaagga ttcaacactt ctagcttcac tcctgtttca ttcgacaatg tctcagctac
    10681 cttcgaagag gcattttctt caaaataaat cactttgatg ttgtttttct tcacaaattc
    10741 ttttagctca gctaagcgac ttggtgtggg ttcctgatct ggtgaaacgc ccgaaatcgc
    10801 tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa gcagcatgct gagtgacaaa
    10861 tgtgcggttt gttgcatctt ttagctcatc ggagtatttt tgatccagtg cttcaagctt
    10921 tttgatataa gcatcggcat tcttcgtaaa agtttccttt ttatctggat atttttcgcc
    10981 taattcttca gcaatcgttc tgacttcttt tatagctaat accggatcga gccaaacatg
    11041 tggatcgtat tcatgtgaat gaccatgccc ttcttctgat tcttcatgtt cgtctgcttc
    11101 ttgcgattct aaacggtcga ttcctttagc tgcttcgatc atcaaggtct gtttgctatc
    11161 cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct gaactattat acacgaaaac
    11221 atctgcatcg gaaatttctg ctctttcttt tgcacttggt tcgaaatcat gcggctccgt
    11281 tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct acgatctctt ttgtaaaatc
    11341 atacatcgga taaaaagtcg taacgatcgt caaatcctct tttttgtctg cttccttgtt
    11401 cgtatttcca catgctgcaa acagtaaagc acctatcatt accgtagctg tcaaaagata
    11461 ttttttcatt tatatgctcc tttcaatgaa caaatcggaa ttttacgatt tattaacgtg
    11521 aactaatgta tcaaaataaa aaaacacagt caatagaaat ccatcaattt ctgatttaag
    11581 catgtatatt cttgattaaa tcgtaaaatg gatgagttgc tgctcatatc tagccatttc
    11641 actacaataa aaaactgaag aataccattt taggattcct cagtttttca tcacctattt
    11701 tacttcttat attttattgc agggttcgta ctaaataaac ttcctcacaa aaacctttta
    11761 acccattata tactctctgc gctcttgaat aatgttgaca caaggcaaaa acggttggtc
    11821 cgcttccact catcaatgca gcatctgctc cgtacttgat catacgctct ttgatttgat
    11881 ggatgactgg atgccgcttt cccgttatat cttctaaact gtttcccatt tttttgatca
    11941 tctgctgata atcttgctct cggatggctt cagcaagtcc gtggatgtct tgatgttgga
    12001 tggcttgcgt atctacttct ctaaacactg tacgtgtaga gacactcatt cttggtttga
    12061 ccaacacaac ccagcactgt ggcatagaag gtaatacttg gatttcttcc cctttgccac
    12121 cgacaaatgc cgtacttccg tagacacagt aaggaacatc tgtaccgact tccaaaccga
    12181 tttctgccag ttcttctaac gaacagccca gattccataa ttggttgatc cctcttagag
    12241 cagctgcaca gtctgtactt cctccgccta atccagctgc tactggaata ttcttcttaa
    12301 caaagatctt gacaccggtt ttgatattgt atttattttt tagcaataaa gcagcttgat
    12361 aaacattgtt ccgttcatct accggtaaaa atgctttatt tgtttctaca atgattttgt
    12421 cttctgttat ttcttcaaaa aatagatgat ctgccaagtc tacgctcgac atcaccattt
    12481 ccaactcatg atacccatct tgccgtctat ataatacatc cagtcctaaa tttatcttgg
    12541 ctggcgcttt ttcaatcaat tccatcctct cacccattcg aaaagtctaa gtcgcaagta
    12601 ttctatcata gggaaaaata aaagtatagc ttatgtctgc ctagtggttg attttgtcat
    12661 cgtttcaaca gctttcacag aattttctct tcataatcca aacaagttct agtgattctt
    12721 ataattctgt gagcacttct tctgccaaac tcggaacatt tcctttttct tttcctatca
    12781 gactgagtag ctgcatggta gcaaatccga aattacttcc tttcctataa gcaaaataac
    12841 gtccttccca atgatcgaca tattttaatt tcttttcata agcagactgg aaggaataga
    12901 aaaaattacc ataattatat acgatatgca tgactttttc ttgaaagaaa gaaaaatctg
    12961 tttctccaac attagctaat ggagctaagc ctagattggc ttccgagtag cccattttct
    13021 cgtatacaat aaacagattg gctaacagat agtcagctaa ttcctcagat tctttaggta
    13081 agacccgcaa caaatcatat cccgcctgct tcttcgtcat cggctgagcg gtgatgaagc
    13141 caacgacttt ttgatcttta cggacaatac cgacaccgct agataataca tatgatttat
    13201 caaatcgtcc cacagagaag tatttttctc gtgcaccttg aagccatttt tgtgaaactt
    13261 catttacagc ttgatgtaat tcttccggca gttgatcgta ccaagtaaaa tggtatcctt
    13321 ctttcatcaa acgttgatat tcaagttgct gactcagccg agacaagtct tctgttgcta
    13381 gatcaacaat ccctgcttca cctactttcg tgaagtgaaa acccaattca tgaagcatca
    13441 ctacgtagct ttctgatatc ttataaaacg caagctgata gcctaaacaa tctgcttgtt
    13501 tcataaactg attcgttgct gcccgcatca ttttaggatt gccaactgga tctcctaaaa
    13561 caaagcattt gtttcctttg atctgataac caaaaacgac ttgatcttgg tcgtcttctt
    13621 ggtaataaaa ataactgtaa cctgacaagc gaagctgatg gcttgtagct gtgcctccgt
    13681 atgtttccaa taaacggtca aaacggtctt tttcgtactc actgccaagc ttcgtagtat
    13741 cttcagctaa atattgataa agcgccacta aagctagcaa tgagatgccc aaaccaataa
    13801 gccctgagaa ccacacatca tctgaaggaa acaaaataaa atgatttcct gttattcgac
    13861 cgactaaaaa gcgtccgctg tgatagcctg caattgcgta aacgataaac aaaaagccga
    13921 acaagctagc atcaaagatt atagctcccc aagaataaac gaattttgtt cgataaaatt
    13981 cttttctgga taaccacaca gctaacagaa tcaagacata taccaatatc aactgccaag
    14041 ataacgtacg tgtgattgta tttaaaatac caaaagatag taaagcaatc gtaggcagaa
    14101 atgccttttt gacttttact gaaagtgctc tagcaaggcc gagtaataaa aagccaacca
    14161 atagattcac tgtctgatct aaaaaattga atgagaacgg caataatact tgaaatagcc
    14221 gactgattgc agacagatta gtgattgttg atagaagtac catcatgatc cccgcaaaat
    14281 agacagcact tacgagcacg atatgcgcaa ccttttggaa aaacagtcgc ggaatgttat
    14341 ctaaaaatcg attgattttg actcctgtat gtgtgatgaa caatagaagt cccgtcataa
    14401 aaggtagaac ataataaaac aaccgataat ataatagcca aactactgct acatcttgcc
    14461 gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc aaaagtcccc attccacctg
    14521 ggaccatcgt cagcattcct atcaatgtag caatcatgaa cataggatag atcgaaagca
    14581 tcgaaatatc tattctcatc aacttgccga tgatcaaaaa taccgcaagg gctcccgtcc
    14641 attgtccaaa ggatgccagt agcagaccaa gcaagccttt tggataaaac tcgaagaaca
    14701 atgtctttct ctttagataa gcaaaaaaga aaatgactgg tgctaaaaaa ctaccgccga
    14761 aaagccagat ccaatagctt cgaaaaatac tttctgactg aataaaaaag acatcaataa
    14821 atgtaagaaa cgaccataca gacaaaccag tcagcataaa tagtgcgact tttgatacag
    14881 tggctaaaac catttttcta tttgtctgct ttccataaaa actagcccgc agacttgctc
    14941 ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt tgttacccac gcagcaagaa
    15001 gaaactcttt tctttccatt tttggttttc cttgtttttc taagactctg atcgtcaccc
    15061 aatcatacaa caacatcgga gtgacaccca gcagtccagc cagaatcatg agcaggatcg
    15121 tcatgcggct ttgttgtccc atcctttgcc aaatatcttg ccaactcatg ccattagcaa
    15181 tatttgcgac ttgatttgcc acaaagacta acacggagcc gaaaaaaatc agttttaaaa
    15241 tcagactatg ttcctttatc cattgcagca tcaagtatcg tttatttttc acattttccc
    15301 attcctaact tgtatacttt tgtgtcatac cccaatgtta tcttatttat tttaattttt
    15361 ccactttaga cctgttcttt gcttgcgatg atagaaaaag aaagatatcc taatgctaaa
    15421 ggagaggata acatgaaagt aggatttatc ggcacaggga atatggcaca agctattatt
    15481 gatggtttat taaaaaaagg aacagtctcg aaagaagagg tgttcgtttc cagtggacat
    15541 tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc atgcatgcaa aagtaatcag
    15601 gaagttgcat cacaatcaga tatcgttctt ttagccgtga aaccaaaaat cattgaaaaa
    15661 gtattggaag aactaagaga atatagccag aaagtcttat tcatttctat tgcttcagga
    15721 aaatcattaa cagatttaga aacagcgctt gaagatcctc aggcctccat cgtacgtgtg
    15781 atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg cgatttgcaa aaatgaagct
    15841 gccacggagg aacagcttca gcaagctacg atgatttttg aagcaatcgg cagcgtctat
    15901 cctttagcag aatcagattt cagtacattc attggccttg ctggcagctc acccgcattc
    15961 gtttacatgc tgatcgatgc gatgggacgg actggtgtac tgaatggttt gtccaaacag
    16021 acagccactg agattgctgc aaaagcaatt atgggttctt gtcaaaaatt cctttcaagt
    16081 gataaaaatc catgggaact tgtagaccaa gtttcttctc ctggcggtac aactgttgca
    16141 ggtgtagttg ccttagaaga agcaggattc atcccagcaa tcatcaaagg aatcaatacg
    16201 acgatcgaga aagatcttga gatgttgaat aaaaaataat gatagcaatg ttttttcgtg
    16261 ccttacaaaa aaagaagagc tgtggctttt gccgcggctc ttcttttgta ttttttatta
    16321 tttagcataa tcagttgcac gagtttcccg aataacgatt actttgatgt gtccaggata
    16381 atccagttct tcttcgattc gtttacgaat atcacgtact aaacgaacag cgtctaaatc
    16441 cgagatttct tctggcttga ccattacccg aacttcgcgt ccagcttgaa ctgcgtaact
    16501 tgattctaca ccggcgaagc tgttcgaaat attttccaga cttcttaaac gacggatgta
    16561 gttttctaat gattcacttc gcgcaccagg tcttgctgct gagagcgcat ctgctgcagc
    16621 tacaaggaca gagataacag aagtagcttc cacatctcca tgatgagaag cgatcgcgtt
    16681 gattactact gggttttctt tgtacttggc agctaattcc gcaccgatct caacgtgaga
    16741 tccttcaatc tcatggtcaa gtgctttccc aatatcatgg agcaacccgg cacgttttgc
    16801 taattggata tcttcgccaa gctctgctgc taagatacca gctaattttg caacctcgac
    16861 cgaatgcttc aagacgtttt gtccataact agttctgaat cgcagacgtc cgatgatctt
    16921 gattagatct ggatgaagtg tatgagcacc gacttcaaac gctgcctctt ccccgtattc
    16981 gcgaatacgt tcatccattt ctttacgaga tttctcgacc atttcttcga tacgcgctgg
    17041 atggattcgt ccatcttgta tcagtttttc caaggtcatc cgtgcgattt ctcttcggat
    17101 tggatcgaat ccggaaagaa caactgcttc cggtgtatca tcgatgatta aatcgatacc
    17161 agtcagcgtc tcaagcgttc gaatattacg accttctcgt ccaatgatac gacctttcat
    17221 ttcatcattc ggaagggtaa cgactgaaac agtcgtttct gaaacttgat ctgctgcgca
    17281 gcgttgaatc gctaatgata ataagttttt cgctttgcga tctgcttctt ctttggcacg
    17341 ctgttcagat tcttttacca ttagagttaa ctcatgattc agctcttctt cagtcgattt
    17401 catgatgaca tctcgtgcgt cctcttttga taaaccagca attttttcta gttctttttg
    17461 ttgatcttca atcatttttt caacgtcttt ttctcgctct tcaattaatt gctgttttga
    17521 actaagtgct tcttctttac tttcaagtga gttctcgcgt ttttctaacg agtcatcttt
    17581 acgattcagc gtttgttcgc gttgaatcaa acgattctct tgagatttta attctaactt
    17641 actttctctc agctcacttt caacttcaga acggtatttc tgattttctt ccttagcttc
    17701 taacaatgct tcttttttta gagtttctgc ttcttttttt gcactatcga tgattccagc
    17761 agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt gactttgcga ccataaaccc
    17821 taaaccaaga ccgacaatta aaccgatgat agcgaggaga atgttgaata ccataaaatc
    17881 cacctccata ctatcttttt catttttatc atctatacag cttctatgat aaattattct
    17941 aaactcgtca atatgcatct tcgcatatat gtgtacaaaa aacatgcaca actttattct
    18001 aatgtttgta
//
LOCUS       DACBYO010000057        17689 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.057, whole genome shotgun sequence.
ACCESSION   DACBYO010000057 DACBYO010000000
VERSION     DACBYO010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.057"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            137..994
                     /locus_tag="IVD26_001880"
     CDS             137..994
                     /locus_tag="IVD26_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAP6079826.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1109..2029
                     /gene="pstC"
                     /locus_tag="IVD26_001881"
     CDS             1109..2029
                     /gene="pstC"
                     /locus_tag="IVD26_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAP6079827.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2029..2913
                     /gene="pstA"
                     /locus_tag="IVD26_001882"
     CDS             2029..2913
                     /gene="pstA"
                     /locus_tag="IVD26_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAP6079828.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2928..3734
                     /gene="pstB"
                     /locus_tag="IVD26_001883"
     CDS             2928..3734
                     /gene="pstB"
                     /locus_tag="IVD26_001883"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAP6079829.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3750..4508
                     /locus_tag="IVD26_001884"
     CDS             3750..4508
                     /locus_tag="IVD26_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAP6079830.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4521..5198
                     /gene="phoU"
                     /locus_tag="IVD26_001885"
     CDS             4521..5198
                     /gene="phoU"
                     /locus_tag="IVD26_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAP6079831.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5436..5735
                     /locus_tag="IVD26_001886"
     CDS             5436..5735
                     /locus_tag="IVD26_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079832.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5761..6468
                     /locus_tag="IVD26_001887"
     CDS             5761..6468
                     /locus_tag="IVD26_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAP6079833.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6465..7232
                     /locus_tag="IVD26_001888"
     CDS             6465..7232
                     /locus_tag="IVD26_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAP6079834.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7332..8900
                     /gene="liaX"
                     /locus_tag="IVD26_001889"
     CDS             7332..8900
                     /gene="liaX"
                     /locus_tag="IVD26_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAP6079835.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9200..9517
                     /locus_tag="IVD26_001890"
     CDS             9200..9517
                     /locus_tag="IVD26_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAP6079836.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            9517..9867
                     /locus_tag="IVD26_001891"
     CDS             9517..9867
                     /locus_tag="IVD26_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAP6079837.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10034..10972
                     /locus_tag="IVD26_001892"
     CDS             10034..10972
                     /locus_tag="IVD26_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAP6079838.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10987..11817
                     /locus_tag="IVD26_001893"
     CDS             10987..11817
                     /locus_tag="IVD26_001893"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAP6079839.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11861..12886
                     /locus_tag="IVD26_001894"
     CDS             11861..12886
                     /locus_tag="IVD26_001894"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP6079840.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12901..13839
                     /gene="galU"
                     /locus_tag="IVD26_001895"
     CDS             12901..13839
                     /gene="galU"
                     /locus_tag="IVD26_001895"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP6079841.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13964..14404
                     /locus_tag="IVD26_001896"
     CDS             13964..14404
                     /locus_tag="IVD26_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAP6079842.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14407..15009
                     /locus_tag="IVD26_001897"
     CDS             14407..15009
                     /locus_tag="IVD26_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP6079843.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15077..16183)
                     /locus_tag="IVD26_001898"
     CDS             complement(15077..16183)
                     /locus_tag="IVD26_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAP6079844.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16393..17394
                     /gene="ccpA"
                     /locus_tag="IVD26_001899"
     CDS             16393..17394
                     /gene="ccpA"
                     /locus_tag="IVD26_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAP6079845.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
BASE COUNT         5781 a         3063 c         3807 g         5038 t
ORIGIN      
        1 agcatagaaa cttttaatga gatagttttt tttacaatta tgagaattta ttttgttatt
       61 taatgatttt gattcgtttt catcaagtaa tgaaaatgat aaaataaaca tactttagga
      121 ttaaaggaga tttctaatga aaaaacttaa attattctta ccaataatag gattagccat
      181 tcttttatca ggctgttcaa agtggattga tcgaggagaa tccattacgg ctgttggctc
      241 ttctgcttta cagcctttag tagaaacagt tgctgaaact taccagacag aaaatcctgg
      301 aaaattcatc aatgtacaag ggggcggaag cggaactggt ttgtctcaag tacagtcagg
      361 agcagtcgac atcggaaact ctgatttgtt tgcggaagaa aaatcgggga tcgatgcctc
      421 agcattagtc gatcatcgag tagcagttgt tgggatcact cctattgtga acaaggatat
      481 tggcgtaaaa gacatcagta tggaaaacct gaaaaaacta tttacaggcg agatcaaaaa
      541 ctggagtgaa gtcggtggaa aagatcagcc agtagttata ttgaaccgcg cttcaggaag
      601 cggaacccgt agcacgtttg aaaaatgggt attggacgga gaaacagctg ttcaggcaca
      661 agaacaagat tcaagcggaa tggtgcgcca gatcgttgcc gacacacccg gtgcaatcag
      721 ctatgttgct ttttcttatg tttccgatga tgtagatacg ttgaatgtta acggtgtaga
      781 accgacagat gaaaatgtga caacgaacaa atggacgatt tgggcatatg agcatatgta
      841 cacaagagat catccaaaaa aactgacaaa agaattttta gactatatct tatctgatga
      901 agtacaagat aacatcgttg gagaactagg ttatatccct gtttctcata tgaaagtcga
      961 acgtgattgg caaggaaata tcgttaaaga gtaatcttta cacaaaattt acaaacttag
     1021 ctaaactttt acatgttatt aaaaccaaat tgatgttcaa tttgtacact gagtgagtat
     1081 gttaaacctg attaaggggg agtcatctgt ggaagatgtg aaaaaagtat tattaacaaa
     1141 atcaaaacgt tcaaaaatgg aacagcgtgg aaaattcatc agttttttat gtatcgcgct
     1201 gatcgtgttg gttgtattat ctatttttta ttttgtagct agtaaaggat tggccacctt
     1261 ttttactgat aagatcaatg tatttgattt tctgtttggt acagattgga atccaagcca
     1321 aatcggagca aatgggaaac caatggtagg ggcattgcct atgatcacag gttcgtttat
     1381 tgtgaccttt ttatctgcta tcgttgccac gccatttgcc attggtgcag cagtattcat
     1441 gacggagatc tctcctaaaa acggaacgaa gatcttacag ccggtcatcg agctgcttgt
     1501 aggtattcct tctgtcgttt atggttttat cggtttatca gttatcgtgc cttttgtcag
     1561 aagtattttt ggcgggacag ggtttggtat cttagctggt acatttgtgt tgttcgttat
     1621 gatcttgccg actgtcacaa cgatgactgt tgatgcatta aaggcagtgc cacggcacta
     1681 tcgggaagct tcattagcgc ttggtgccac aagatggcaa acaatctaca aagtcgtgct
     1741 acgagcagcc gtgcccggga ttttaacagc agtcgttttt ggtatggctc gtgcgtttgg
     1801 tgaagcctta gctatccaaa tggtcatcgg taatgcagca ttgatgccaa caggacttac
     1861 tactcctgct tctacattga cgtccatctt aacaatggga atcggaaata caatcatggg
     1921 aacagttgaa aataatgtgt tatggtcatt agcgctgatc ttgctattga tgtcattatt
     1981 ctttaatatc gtgatccgta tgattgggaa gaaaggagag ctgaaataat gaacgcaaaa
     2041 cgctcagata aaattgctac aggtgtttta tatatagttt cggggatcat cgtattgatt
     2101 ttagcagctt tactacttta tatcttagtt cggggaatac cgcatatttc atggtccttc
     2161 ttgaccgaac cttccaaagc ctaccaagaa ggcggtggaa tcgggatcca gctatttaac
     2221 tcgatttatt tgcttttgat cacgatgatc atcagttttc ctatttcttt aggtgcgggt
     2281 atctatcttt cagaatatgc tggaaaaaac tggctaacag atgtgattcg cacgtcgatt
     2341 gaaatcttga gctcgttgcc ttctgtcgtt gtcggtttat tcggtttctt ggttttcgtt
     2401 attcaattcc agtatggttt ctcgattatt tctggtgcat tggctttgac tgtattcaac
     2461 ttgcctcttt tgactagaac agttgaggag tctttacaag cggtccatta cacacaacga
     2521 gaagcaggat tggccttagg tttgtcacgc tgggaaacag tgataaaagt ggtggttcca
     2581 gaagcgacac cagggatttt gactggtgtg atcctaagtt ctggaagaat ttttggtgaa
     2641 gcagctgcat tgatctatac ggctggacaa agtgcacctg cgttagattt tacgaactgg
     2701 aatccattaa gtgtttcaag cccgatcagc attttccgtc aagctgaaac attagctgtc
     2761 catatttgga agatcaatac agaaggcacg atgcctgatg gtgtttctgt ttcggctggc
     2821 gcttctgccg tgttgatcat tgctgtttta ctgttcaact tcggcgctcg tgcgattggc
     2881 aaacgattat accgaaaaat gacttcagcc taaggagaag aagcaaaatg aaaaaatata
     2941 actggaatga aacaaatgtc atcaccatgc caaaagagaa agaagtagca ctatatacgg
     3001 atgatctaca tgtctggtat ggcgacaatg aagcaatcaa aggagtggat ctggaatttg
     3061 aaaaaaataa gatcactgca ctgattggtc cttccggctg cggaaaatct acgtatcttc
     3121 gttcgttgaa tcgaatgaat gatgggatcg ctaatacgaa aatcactggg aaaatcatgt
     3181 atcaaggcgt agatattaat gcgcctcaag tggatgttta tgagatgcgc aaacggattg
     3241 gcatggtttt tcaacgtcct aatccgttca gcaagtcgat ttatgacaat attacatttg
     3301 ctttgaaaca gcacggcgaa aaaaacaaaa agaaattaga tgaaatcgtt gaaacaagct
     3361 tgaaacaagc tgccttgtgg gaccaagtaa aagacagctt ggacaaaagt gccttggctt
     3421 tatctggcgg gcaacagcaa cgtttatgta ttgctcgtgc gatcgcgatg aaacctgata
     3481 tcttgctgct agacgagccg gcaagtgctt tggaccctat ttcgacagga acggttgaag
     3541 aaacacttgt aaacttgaaa gaagactata cgatcatcat cgtgacgcat aacatgcaac
     3601 aagcagctcg tatcagcgac tatactgcct ttttctatct aggaaaagta atggaatatg
     3661 acaaaactaa caagatattt accagaccaa aaattcaggc aaccgaagat tatgtgtccg
     3721 gtcattttgg ttaagacgga ggcctcaaca tgacaaaaga aattatttca tctaaagatc
     3781 ttcatctgta ttatggaaag aaagaagcac taaaagggat caatctaagt ttcaatcaag
     3841 gggaaatcac tgcgatgatc ggtccttctg gttgcgggaa atccacttat ctgcgttctt
     3901 tgaaccggat gaatgacctg attccgaatg taacgatcac cggaagtgtt ttatataaag
     3961 acaaagacat ctatggtcca aaaacagatg ttgttgaact aagaaaagaa atcggcatgg
     4021 tattccagca gccaaaccca tttccttttt ctatctatga aaatgtcatc tatggattga
     4081 aattaaaagg ggaaaaagat aaaaaagtcc ttgatcaagt agttgaagaa agcctgaagg
     4141 cagcgtctgt ttgggatgat gtgaaagaca aattgcataa aagtgcttta tctttatccg
     4201 gtgggcagca gcagcgtgta tgtatcgcac gtgttttggc agttaatccg gaaatcatct
     4261 tattggatga accaacaagt gcgcttgatc ctgtttctac tgggaaaatc gaaagtatgc
     4321 tgttagaatt aagagagcgg tatacgatga tcatcgtgac ccataatatg tctcaagctt
     4381 cacgtatttc agataagacg gcattctttt tagatggtca cttgatcgaa tacaacgata
     4441 cgaagaagat attcatgaat ccagaaaaac aagagacaga agattatatt tcaggtcgat
     4501 ttggataagg aggaaacgga atgctacgta cacaatttga agaagaattg ctgaatctcc
     4561 ataatcagtt ctacgaaatg gggatgatgg tgagcagcgc cgtgcacaag tcagttcgtg
     4621 catacatcaa acacgataaa atcttagccc aagaagttat cgaaaacgat ataaatatca
     4681 ataacatgga aacacgcttg gagaagaaaa gttttgaaat gatcgcattg caacagccag
     4741 ttacaactga tttgcgtatg atcattacgg tcatgaaagc tagctcggat ttagaacgta
     4801 tggccgatca tgcggtgtct gttgctaaat ccacgattcg cgtaaaaggg cagacgagaa
     4861 taccggaaat cgaaaaagag atctccgata tgtccgatta tgtgaaaaaa atggtggaca
     4921 acgtcctagt tgcttatgtc aaaacagacg aaaaagacgc acgtacgatc gccaatatgg
     4981 atcaaagagt caatgactat ttcaatcgaa tctataatgc aacaatcaaa aatatgcagg
     5041 aaaatcctga gacagtcatc agtggaacag actacttgaa tgttgccagt tatctagaac
     5101 ggatcggaga ctatgtgaca aacatctgtg aatggatcgt ctacttggct acagggaaaa
     5161 tcactgagtt aaatacgaac cacaatgaga ttttctaaac tgaagctgtg attatgccgt
     5221 ttgtttagga aaagaggttg tgaaatcagc ggttgtgaaa aagctgttct gcatcaagta
     5281 ataagaacag tcaaacaaaa aatagctcct catatttttc gtttggctgg acttattacc
     5341 gcagatgcaa gcttttgaac accgtttatt cgggaaaggg tttgtgacaa aacatgtcac
     5401 aaaccctttt catcatttca tagaaaggat aaagaatgca aaaaaaaatt agcatcatca
     5461 ctatattttt tatttgtgtg cttacttcat gggttattca gcatcaagct gctttatatg
     5521 aagtacctgt catcgagatc gaaaaagtac gaataaaaga ggatcatcaa ttgattacag
     5581 gaagactgat gaacacggat caaaaaggag aatcgattta tttatcggtt ccttatcaaa
     5641 aaaatcaaat agaaacagca aatataaaag cgagacaaat gtatctagtc caaatgcatg
     5701 gagatgaatg gcagctagta gcaaaaaaaa aatgatggct ggcttttctt cttcacaagt
     5761 atctccattg gcgccatgtt gcttattggc ggaaaacagg gtctatttgc tttaggaagt
     5821 ctcatcatca atatcgtttt acttttactt ttgttgctca tctttactaa aacagaaggg
     5881 atttctctat taaatatatc tatcctgttc gtcgttatag ggatgattat tagcatattg
     5941 gctttagatg gatggaatag aagcagtata atcaaaattt cagctgcagt tacgagtgtt
     6001 tttttagcat tttttatttg tcttttgaca atgaatcatt ggaaagacca aggactgcgc
     6061 tatgaggaac tgaattatct gacacgaccg tatcgttctg tttttctttc tagcgtactg
     6121 attggaacag ctggaggaac actcgatacc gttatcacag tcattgcgac attagaagaa
     6181 ttgactaagc gacaaccaga aataacagcg aaacagttat ggctttcagg aaggcaagtg
     6241 ggtcgagatg tgattggctc gatgaccaat atccttttgt tcgtctatat cagtgggtca
     6301 gttccatcgc ttcttttata tttaggaaat caatggtcgt tcaaagaaac gatagaacag
     6361 catttatcat tggaattttt acgcgtcatt gctggcagct taggaatagt attatcgatc
     6421 cctatctcgg tcctcttttt tctgactgta aggaggctga aacgatgaat gtacttatta
     6481 tacttgttgg gattttagca atcagcgtgc tacttattgg cggtacgcaa ggtatgtata
     6541 ttcttttagg cttattcatc aatttaggga tctttttcct gttgttattc ggttatcatc
     6601 agaagtggcc gatactggca ttgtcggtca taggattttt attgattgct gtggttatct
     6661 tattttttat caacggttat aatctaaaaa tgcgtgcagc ttttgtgagt atactgatct
     6721 ttttattttg tttcctacta ttgcttccta tcactgattt tttagcgatc caaggtttta
     6781 catcggtaga actagaagaa ttatctggct tagataagac tttagcgatt gattttagat
     6841 tacttacgag atcgttgctt ctgattagtc ttagtggtgc tgttttagat gctagtgtag
     6901 caatttctag tgggacattc gaagtatatc aggcaaatcc gcaattatct ttttaccaat
     6961 tgcgccattc tagtttcgct attgctaaaa aaatattggc gtcaacagta atgacacttc
     7021 tttttgcatt catgggaagt tctttagcgt tgatcctctg gtttattgat ttagacattc
     7081 cttttcagca agtgatcaat gaaaaatcat ttgttctaga atatacgatg gctattctta
     7141 ccacattgtc tgcactactt gttcttcctt taacctgcgt gactacagca tatctcttta
     7201 caaaaaagaa agaacaactc aagatggagt aaaagttaca acttaagtcc tatgacattt
     7261 ttactgaatc agtgcataat atggatgtaa ggaaaagctt gcaaacaatt ttgcttaagg
     7321 aggcaatttc catgaaagaa agagaacgta ttttagattt agtgaaaaaa ggaatccttt
     7381 cgactgaaga aggcttagat ttattagaaa gcatggcaac tgaaaaagac gaaaagcaaa
     7441 taaaaaaaga agcagacaag gtaactgcta gtcataaaga aaaagatcag gcaagtcaat
     7501 tgatcgataa acttgaaaac ggcgaagaag aaatttctga gccagttgat ccaaaggaaa
     7561 gagaaaggca agatcaagaa aacttagaaa agatcttaga tgaactagca actgaagcga
     7621 ataaaacttc ggcgcgtcta gatgaagtaa atgctcaatt cgctgacaat aaggcagcac
     7681 gcaatgagaa acaggaagca ttgatgcagc tgaatacaaa agaagaatta ggcgagttga
     7741 cagaagaaga attagcacag cgtcagacgt tagaagcaga aatcaaagaa ttagaagcta
     7801 gtggcgatac actgttagaa gaacaattga aattagaagc agaattaaaa gatatccgta
     7861 agaatcaatg gtctgagaaa aaagaaacgt ttactgataa gtttgaattg ccagatgatt
     7921 ggaaagatca agcaacagat acactgaatc aagtaggcga aaaaatgtca gaagctggat
     7981 cacagttagg caaattcttg aagaaaacat tccaaactgt ttcagaaaca gtgaatgaca
     8041 acatggaatg gaaagatgtc agcttacgtg tccctgggat tgcgacaacg aaatttgagc
     8101 atgaatttta ctatgaagct cctgcagcaa gtatccttga tatcaaggca gcaaacggaa
     8161 acgtgacgtt aaaaacgtgg gacagcaacg atgtgaaagt tgaagctaag atcaaacttt
     8221 acggaaaaat gggtgctgaa ccatttgaag cattctctga acggagccag attgaggtta
     8281 atgaagatca tatctccttc caaattccaa ataaacgtgt gcgtgcagac cttgttttct
     8341 acttacctaa acgagtatac gaccacgcag ctattaaact tctaaatggc aacatcatga
     8401 ttgaaacatt ggaagctaaa gatatttata caaaatctac gaatggtaac atcatcgtgg
     8461 accaattaac tgcaacgatg ctggaagtag aaggtgtaaa cggcaatatc gatattcgaa
     8521 acgggaacat cttagattct attatcgaaa cagtaaatgg tacagtgaca tttggtgcga
     8581 cagcagaaaa cctttctgtg tctttggtaa atggtgatgt acgtcttacg attaaagaag
     8641 ataatttgaa aaaagtagaa gcaagttcag tgaacggaaa tgtcaaagtc gctttaccag
     8701 atggcatcgg tttggaagga catgctaaaa caagtcttgg aagtatcaac agccgtctgt
     8761 ccaattacga agtagttcgt gagaaaaaag aacggacaaa ccaaatgttg caattccgtc
     8821 gtgtttcaga tggtgaaatc acgcaagtgc aactttcaac gacaacagga agtatctatt
     8881 taaaagatac agataaataa agaggttgtg aaagagatgt tcagccttga gcaataagaa
     8941 gcgattttgt aaaatagctt cccctatttt acaaaattgt gccttattgc cgataggcta
     9001 tctcttgaac accgtttacc aagagattat gaacctgcca attatcgccg agtcacaagg
     9061 aataatttca gaaaaagctc gtcacgtttt atgaatatgg taatttgtga ccgagaattt
     9121 tgcagaaaga caccgattaa gaagaaggtt gtcacaacga ttttcttcat ttaaaatagt
     9181 agaacagagg tgagacatga tgaaaaaaaa gttgacaaaa tccaataaaa atgttgtttt
     9241 gacagggact ttagcaggaa taggagaata catcgggatt gatccgactg ttatccgtgt
     9301 gctttatgta ttcctgagct tagttgcttt tggaagtcca atcattttat acattttatt
     9361 agctttgatt atcccatctg cgcgttctgc acgaacaaac tatggacata acaatgcata
     9421 ttatgaaaaa aacaattatc gtgaacaaac tcgtgaacaa acaaaaaaac gcaaagaagc
     9481 ggaaaaaatc gatgatgacg aatggagtga cttttaatgt cgtactttca acgtatttta
     9541 gttaatacgt taacattcat atcattggct gttctttttc ctgcgatggt ccatgtgagc
     9601 agtatttgga cggccgttct tgccagcttc gtattgtctg tgttgaatat gtttgtcaaa
     9661 ccgattttga cgatactgtc cctgcccttt acattagtca cattgggatt gtttacgttt
     9721 gttatcaatg cagcgattct taaaatgacc tccttttttg tgggagcaga acattttagt
     9781 ttttcttcat tcggtgcagc gttgttagta gctatcttga tgtcgcttgt caatgtaatt
     9841 gtcagtgaac ataacagtag aaaataaaag aaagctgtgc cgaactatcg gcgcagtttt
     9901 tttatttaga atcaggaatg cgttttctat tacattggta attaaataaa aacgtttttt
     9961 ttaattggta gtacttttgg ctagacaatg ataaaatgat agagaacact ctaatagaaa
    10021 tgaggtagca tgaatgtcag aagttgtaaa agttagccaa ttagtgaaaa aattatcttt
    10081 ggaaatcgtg acaggcgacg agaaaagctt agaccgtgtc atcgtaactg gggacatctc
    10141 acgcccagga ctagagttga ctggttattt taattattat tcccataatc gtttacagct
    10201 atttggcagt aaagaaatca gttttgcgga acggatgatc ccagaagagc gtttgatcat
    10261 catgagaaga ttatgtagtg aagatatgcc cgcatttatt atttcaagag gattaccggc
    10321 tccagaagaa atgatccagg cagcaaatga aaatgggata gctgtactgc gttctcccat
    10381 ctcaacttct cgtttattag gagaattatc cagttattta gatggtcgcc ttgcccctcg
    10441 aacaagtgtc cacggtgttt tagtggatgt ttacggatta ggtgtactga ttcaaggtga
    10501 cagtgggata ggaaaaagtg aaacagcgtt ggagttgatc aaacgcggtc atcgattgat
    10561 cgcagacgat cgagtagatg tttatcagca agatgaatta acggtgatcg gagaaccgcc
    10621 taaaatcctg gaacatctaa ttgaaatccg aggaatcggg atcattgatg taatgaatct
    10681 ttttggtgcg agtgcggtac gtggctctat gcaagtccag ttggctgttt atctggaagc
    10741 atgggcaaaa gataagaaat acgaccgtct gggctctgaa gacacgaccg ttgaaatcgc
    10801 ggaagtgggc attccacaaa taaaaatccc tgtcaaaaca ggacgaaacg ttgcaatcat
    10861 cattgaagta gccgcgatga atttccgtgc acgtacaatg ggctttgacg caacgaaaac
    10921 atttgaagaa agattaagtc gcttgattga agaaaactca ggcaacgact agcaaggagt
    10981 gacaatatgt tagcacaaat caatcgagtt gcttttgagc ttgtagggat tcctatctac
    11041 tggtatgcat tgatcatcgt atcaggtatc attatcgcca tgtggcttag cagcagagag
    11101 gctgttcggg taggattaaa agcagatgat gtgacagatt ttatgttgtg gggattgcct
    11161 atctccatta ttggtgctcg cttatattat gttttatttg atcttcccca gtatatagct
    11221 gatccaatcc aaatattcaa tatccgttca ggaggcttag ctatttatgg cggactgatt
    11281 gcaggcgcga tcacgctgta tttttttact aaatatcatt ttatttcttt gtggactttt
    11341 ttagatatcg ctgcaccaag tgtattatta gcacaggcaa tcggtcgttg gggaaatttc
    11401 atgaaccacg aagcatatgg accagacacg acgcgaagct tcttagaaag tctgcattta
    11461 ccgcaattca tcattgataa tatgtatatc gaagggatct atcgtcaacc aacatttctt
    11521 tatgaatcac tttggagttt gattggattt attttgcttt tgtttttacg aaagaaacca
    11581 caccttttga aaaaaggcga agtcctttta tgttatctaa tgtggtatag tttcgggcgt
    11641 ttctttattg aaggattacg tacagacagt ctttactttt taggtgtgat ccgtatttct
    11701 caattattat ctgctgtgtt atttgtcggt acattgattc tatttatttg gcgcagaaaa
    11761 aaaggaaatt taccggatta tgaccgctca ttaggaaaaa atcaacaaat tatctgattt
    11821 ttagagcgtt aaaaatgaaa aaaatttcag gagtggtaaa atgaattata gagtagcggt
    11881 tttaggacca ggctcttggg gtactgcttt ggcacaagtc ctcgccgaaa acggacatga
    11941 cgttcggatt tggggacatc gtgcttcaca agtagaagaa atcaacaccc aacacacgaa
    12001 tcaacgttat ttaccagatc attatctacc cgattccatc caagcattca ccaatatgga
    12061 agatgcagta aaagacgcag atgcggtgct attcgtcatt ccaacgaaag caatacgttc
    12121 tgttgcaaaa gaactagtgc ctaaattgaa tacaaagcca gtgatcatcc atgcaagtaa
    12181 aggattagaa cagggaacac ataaaaggat ctctgacatc ttgttagagg aaatcccagc
    12241 agaaaaaaga aaagctgttg ttgttctttc tggaccaagc catgcagaag aagtagcgaa
    12301 acatgacatc actacgatca cagctgcaag tacagatgca aaagcagcaa aatatgtaca
    12361 agagctgttc atgaataatt attttcggat ctataccaat cctgatgtga tcggtgtaga
    12421 gatgggggca gctttgaaaa atattattgc tattggtgct ggcgctattc acggcttagg
    12481 gtttggcgat aatgcaaagg cagcaatcat gacgcgcgga ttagctgaga tcagccgttt
    12541 aggtgtagca atgggtgcca acccgctgac ctttatcgga ttaagcggag taggcgatct
    12601 agtcgttact tgcacaagtg ttcattctag gaactggcgc gcaggcaact tgttaggaca
    12661 agggcagccc ctagaagagg tgctagccaa tatgggaatg gtcgttgaag gtgtgaatac
    12721 tactcaagca gcgatggaac tagcccaaat aatggaaatc gaaatgccca tcactcaaac
    12781 aatctatgaa gtgctgtatg aacaaaaaga aatcaaaaca gccgcaaaag aaatcatgtt
    12841 acgtgatggg aaaaaagaaa atgaattctc attaacaatt ttttgaagga gcgaatgtat
    12901 atgaaagtca aaaaagcagt tattccagcg gcaggattag gaacaagatt tttaccagca
    12961 acaaaagcta tggcaaagga aatgttgcca attgttgata aaccaacaat ccagttcatc
    13021 gttgaagaag cgttgaaatc aggaatcgaa gacatcttga tcgttacagg aaaagctaaa
    13081 cgaccaatcg aagatcactt tgattcaaat attgaattag aaacaaacct aagtgaaaaa
    13141 ggaaagaccg aattattgaa attagtagaa gaaacgacag atgtcaactt gcatttcatc
    13201 cgtcaatctc atccaaaggg tttaggacat gccgttcttc aagcaagagc ctttattgga
    13261 aatgaaccgt ttgtcgttat gctaggcgat gatatcatgg aagatgaagt accattgaca
    13321 cagcaattaa tcgatgatta cgaacgtact catgcttcta cgatcgccgt tatgcaagtt
    13381 cctcatgatg aaacttcaaa atacggaatt atcaatccag gagaagtatt ggaagatggg
    13441 ttatacaatg tcaaaaactt tgttgaaaaa ccagatccaa gcaaagcacc aagtgattta
    13501 gctattattg gacgttactt attgactcca gaaatttttg atgtattgtc cgagcaacaa
    13561 ccaggagccg gaaatgaaat ccaactaact gacgcaatcg atacattgaa taaaacacaa
    13621 cgcgtatttg cccgtaaatt cacaggtaaa cgttacgatg tcggtgacaa atttggtttt
    13681 atgaaaacaa gtattgaata tggtctaaca catccagaag taggtgcacc tttacgtgag
    13741 tatatcctgt ctttaggtaa aaaattagaa gcagaaggaa gcaagatcga tcataatcca
    13801 aaaggaataa cagaaatcaa agaagaaaag aaaaaataac ccttttttct aacgagcttc
    13861 agctgctaat tgaataaaaa gtagttgaag ctcgttttta tttgtttaaa aaacacgaaa
    13921 atgctatcct tatagaaaag agagacaaga agggagtttg atcatgtcag gaggagaaat
    13981 tgcaggattg atcgcagcaa tcgcctttgc gatacttgtc gtttttatcg ttcgtgtgtt
    14041 gttgcaagtt tctaaaactt tagaaaaagt agatcagact gtagcagaag caaatacgac
    14101 gatcgaaatc gtcacaaaag acgtagatct tttgtctaga caagtagaag gcttgctggt
    14161 caaaagtaat gaactgctct tggatatcaa tggaaaagtc gcaacgatcg atccattgtt
    14221 cacagcagtt gctgatttaa gtgaaagtgt atcagaactt aatcattcta gtaaaaacat
    14281 cgcgacgaaa gtcggcggaa tcggtaaaac gacagctaaa gcgacggttg ccggaaaagt
    14341 cggtgggaca gcgatgaaat tttttaaaaa caaaaaacat actgaaacga caggaggaaa
    14401 ataaaaatgg ctaaaaaagg tggattttta ttaggtgcag tagtcggagg aacagccgca
    14461 gcaatcgccg cgttattgtt agcaccaaaa tctggtaaag aacttcggga tgaattagct
    14521 gcccaagcgg atgatttgat ggatatggct tcagattaca cagatatggc gaaagaaaaa
    14581 tcgactgagt taacaggtat tgcaaaagaa aaagcgcaag atctttctca acaagcaggt
    14641 gatctagcag gtagtgtcaa acaaaaagta agtgaatcag cagatgaagc aggaagtgaa
    14701 tctgacgata tcttgttaaa tcttaaagaa caatcagctg acttatctaa tcgtttcaaa
    14761 aaaacggcag aagatatgaa aaaacctgca gatgaattag gaagtattgc taaagatact
    14821 tcagaagata tcatgattga tgtaaaagac gctgctggta aagcaggaga tactgtcaat
    14881 gaaggaatgt cagaagcaaa accagttgca gatgacacaa aagaaatgat gaaaatggca
    14941 aaagaagatg cgaaagaagc taaaaaagaa ataaaagata caatgacaga ttcatctaca
    15001 aatcactaaa atcactaaaa tcacaaattt atagaataaa aaggtgggag cggactagct
    15061 ctcacctttt ttactcttat ttttctaaaa ctagtaattc ttttggtgta gtcgtgaatg
    15121 gcacacagcc atcgcttgtc acatatacac agtcttcgat acgtacccct actttttcag
    15181 gaatatagat tcctggttca agagagaagc acatcccttc ttcgattact aagtcatttc
    15241 cttctacaag ggaagggaat tcgtggacgg ttgttccgat cccgtgacct aaacggtgat
    15301 tgaaatattc gccgtagcca tagctgttga tcacgtttcg tgcgatttga tcaagttcac
    15361 ctgctgtcac acctggacgg acggcttctt gtgcggcaag ctgtgcttca agagtgatgt
    15421 tgtatatttt ttcttggaag tcggttggtt tttgataagc aattgtacga gtagcatcac
    15481 tgcaatagcc attccaaaca acgccaagat cgaataacac aagttcattc ggtgaaatct
    15541 tcgtgtttcc tggtgtacca tgagggcttg cagcatttgc tcctgcaagg actaatgtgt
    15601 cgaaagacat ttgtgaaaca ccttgttttt tcaattggta ttcgatttct gcaatgatcg
    15661 cttgttcagt cacgccttct ttcactgctt taaagccaat ctcaaatgca acatcggccc
    15721 atttaccagc ttcgatcagt ttgtcttttt cctctagagt tttgatcagt tgtagacgtt
    15781 ggatgatgga agctagatca gtgtaagaat ccgttcccgt caagatatca gagatagcat
    15841 cgaagcgctc gacagtcaag gcgttctttt caatccctac attgccaggc tgaccatagc
    15901 gagcacgaag ttcttttccg atgatctccc aagggttttc gctgtctaaa tagccacgga
    15961 catcatacgc ccaactactg ttttgagcat cttcaacttc caaagcagga gtgaaaagga
    16021 aaggatcttg ttcaagaggg ataaaaagag ctagtacacg ctcatgagga tcactttcgt
    16081 atccggaaaa gtaagcgatg tggccagggt cgctgatata agccaattcg acttggtgtt
    16141 gtgccatcca ttgacgtagt tcattgattt ttacgttatt catttggcaa cctactttct
    16201 aaattaattt tgtattcaat aattgtacca ctgatttatt aaaagaccaa cgttctaaaa
    16261 actgaaaaaa gtaaaaattt tcatgaaaac agagataaaa cggttgcaat tcttgagatt
    16321 atttgatatt ctattttaga aatgtaagac gtattttcag aaaacatata aaatatgaat
    16381 aggagaacac aaatggaaaa gcaaacaatc actatctatg atgtagcgag agaggcaaat
    16441 gtttcgatgg ctactgtttc acgtgtcgta aatggcaatc caaacgtcaa accagcaaca
    16501 agaaaaaaag tcttggaagt tatcgatcgc ttggattatc gtccaaacgc agttgcgcgt
    16561 ggcttggcaa gtaagaaaac aacaacagtt ggggtaatca tccctgatgt cagcaatatg
    16621 ttctttgctt ctttagcacg tggtatcgat gatgtggcaa caatgtacaa atacaatatt
    16681 atcttagcaa attcagatgg taacgaccaa aaagaagtca atgtattgaa taacttactg
    16741 gctaagcaag tggacggcgt gatcttcatg ggtcaccata tcacagacga aatccgtgga
    16801 gaattttcac gttcaaaaac tcctgttgta ttagctggct ctattgatcc agatgaacaa
    16861 gtaggtagcg taaacattga ttatgtatca gcaacaaaag atgcagtaaa caaattggca
    16921 aaaagcggca ataaaaaaat cgcttttgtc agtggtgcgt tgatcgatcc tatcaatgga
    16981 caaaatcgtc tgaaaggcta taaagaagca ttaagcgaaa ataacctacc atatagcgaa
    17041 ggattgatct ttgaagcaca atacaacttc aaagatggtc tatctctagt cgatcggatc
    17101 cataatagcg gtgcaacagc tgtctatgtt tcagatgatg aattagccat cggtattttg
    17161 gatggtttat tagaccgtgg cgtgaaagta ccggaagaat tcgaaatcat cacaagtaac
    17221 aattcactac tgacagaagt agctcgtcct cgtttaacaa gtatcacaca accattatac
    17281 gatttagggg cggtatctat gcgcctattg acgaaaatga tgaataaaga agaagtcgaa
    17341 gaaaaaacga ttatcttgcc ttatggaatc gaagaaaaag gatctacaaa ataataaaag
    17401 gacaaccatt cagaggttgt gagcctgccg tttaactctg cgttacaagg agcaatttca
    17461 aaaaacagca tttcatgttt gatgaatatt gtgactcgtg attcggagtt ggcaggagaa
    17521 caccgtttat tcgggaaaag gggttatgac aaaattttgt ttaatccttt ttttttgtct
    17581 taaaaaagag agaaagtggt tgaaattaca tttatcgtat ataaaacaat ccgtgtatag
    17641 atgctgcatt atgttcacca ccatcaaaaa aataagggac tgtgacaat
//
LOCUS       DACBYO010000058        17422 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.058, whole genome shotgun sequence.
ACCESSION   DACBYO010000058 DACBYO010000000
VERSION     DACBYO010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.058"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            67..297
                     /locus_tag="IVD26_001900"
     CDS             67..297
                     /locus_tag="IVD26_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAP6079846.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            394..1695
                     /gene="murA"
                     /locus_tag="IVD26_001901"
     CDS             394..1695
                     /gene="murA"
                     /locus_tag="IVD26_001901"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP6079847.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1708..1884
                     /locus_tag="IVD26_001902"
     CDS             1708..1884
                     /locus_tag="IVD26_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP6079848.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2019..2315
                     /gene="yidD"
                     /locus_tag="IVD26_001903"
     CDS             2019..2315
                     /gene="yidD"
                     /locus_tag="IVD26_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAP6079849.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2379..2846
                     /locus_tag="IVD26_001904"
     CDS             2379..2846
                     /locus_tag="IVD26_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6079850.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            2931..3815
                     /locus_tag="IVD26_001905"
     CDS             2931..3815
                     /locus_tag="IVD26_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6079851.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            3932..4165
                     /locus_tag="IVD26_001906"
     CDS             3932..4165
                     /locus_tag="IVD26_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAP6079852.1"
                     /translation="MSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4253..4333
                     /locus_tag="IVD26_001907"
     tRNA            4253..4333
                     /locus_tag="IVD26_001907"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4287..4289,aa:Tyr,seq:gta)
     gene            4340..4411
                     /locus_tag="IVD26_001908"
     tRNA            4340..4411
                     /locus_tag="IVD26_001908"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4372..4374,aa:Gln,seq:ttg)
     gene            4927..5634
                     /locus_tag="IVD26_001909"
     CDS             4927..5634
                     /locus_tag="IVD26_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6079853.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5693..6337)
                     /locus_tag="IVD26_001910"
     CDS             complement(5693..6337)
                     /locus_tag="IVD26_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAP6079854.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            6464..6751
                     /locus_tag="IVD26_001911"
     CDS             6464..6751
                     /locus_tag="IVD26_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079855.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            6859..7179
                     /locus_tag="IVD26_001912"
     CDS             6859..7179
                     /locus_tag="IVD26_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6079856.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            7497..8573
                     /locus_tag="IVD26_001913"
     CDS             7497..8573
                     /locus_tag="IVD26_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP6079857.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            8570..9289
                     /locus_tag="IVD26_001914"
     CDS             8570..9289
                     /locus_tag="IVD26_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAP6079858.1"
                     /translation="MRCSCCGKDIIQNLTFSEIIGVSKSRLPQTCSVCRAQFHLLEAK
                     GCAGCQKPIHLKYEETKKKANTSFVYCNDCQEWKKKYPAYDFQHRAFFTYDEKMQAWI
                     NRYKFMGDIRLAGTFAYKWTQIKKDYPAYIYCPIPLSEKRWLERGFNQVSEMLKAAKI
                     PFQMLLKREQHLLAQAKNTRKERLEMPQPFELAVPLSKIQHKKILIIDDVYTTGQTLF
                     HAADCLQNAQPKIIRTISLAR"
     gene            9417..9968
                     /gene="raiA"
                     /locus_tag="IVD26_001915"
     CDS             9417..9968
                     /gene="raiA"
                     /locus_tag="IVD26_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAP6079859.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10190..12724
                     /gene="secA"
                     /locus_tag="IVD26_001916"
     CDS             10190..12724
                     /gene="secA"
                     /locus_tag="IVD26_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAP6079860.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            12850..13951
                     /gene="prfB"
                     /locus_tag="IVD26_001917"
     CDS             join(12850..12912,12914..13951)
                     /gene="prfB"
                     /locus_tag="IVD26_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAP6079861.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14056..14742
                     /gene="ftsE"
                     /locus_tag="IVD26_001918"
     CDS             14056..14742
                     /gene="ftsE"
                     /locus_tag="IVD26_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAP6079862.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14726..15619
                     /locus_tag="IVD26_001919"
     CDS             14726..15619
                     /locus_tag="IVD26_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6079863.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            15771..17219
                     /gene="cls"
                     /locus_tag="IVD26_001920"
     CDS             15771..17219
                     /gene="cls"
                     /locus_tag="IVD26_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP6079864.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
BASE COUNT         5827 a         2957 c         3795 g         4843 t
ORIGIN      
        1 ttatacattt tatggtatta tcattttatt agttattata aaacaatcgt tagaaaggac
       61 gtcattatgc aagtatacgg aattgatgcg gtgcttcgaa tcgtgagtca tttggcgttt
      121 atctacttag ccttctggtc tttacgttcg ttacgcattg aaactttttt cagaccaatg
      181 cataatacgc aaattagaat ggcaatcgta cttttttcaa tttttttagg gtacactgca
      241 agtaattttt tcttagaggt tatcgcttta tgccgaaatc ttttcgttag cctgtaaatt
      301 ttaaaaaaag gtactatttt aaaagcaagg atgttataat agaaaagatt ttgagtaagt
      361 gtatgctcat tggaattttt tggagggaac aacatggaag agatcatcgt aagaggtggc
      421 aatcaattaa atggaacagt aagaattgaa ggagctaaaa atgctgtttt gcctatttta
      481 gctgctagtt tgttagcaga agaaggtatt acgacattag acaacgttcc gattctttct
      541 gatgtcttca ctatgaatca agtgattcgt cacttaaacg tagatgtaga ttttgatgaa
      601 caaaagaatc aagtaacaat cgacgcttca agacaattag aaatcgaagc gccttatgag
      661 tatgttagtc aaatgcgtgc ttcaatcgtt gtgatgggtc cgctacttgc cagaaatgga
      721 catgcaaaag tagctatgcc tggtggatgt gcgattggta aacgaccaat cgatttgcat
      781 ttaaaaggat ttcaagcttt aggagcaaaa attattcaaa aaaacggcta tatcgaagca
      841 attgcggatg aattgatcgg taacacgatt tatttagatt tccctagtgt aggtgctact
      901 caaaatatca tgatggctgc cgtaaaagca aaaggaacaa ccatcattga aaacgtagct
      961 cgcgaaccag aaatcgttga tttagcaaac attttgaata aaatgggcgc tcaagtctat
     1021 ggagctggta ctgaaacaat gcgtattgaa ggcgtggatc atttacatgc agtcaaccac
     1081 tcaatcgtac aagatcgtat cgaagcaggt acctttatgg ttgctgctgc aatgacacaa
     1141 ggcaatgtgc tgattgcaga tgctatctct gaacataacc gcccattgat ttctaaattg
     1201 atcgaaatgg gtgcagaaat cattgaagaa gaaggcggag tccgtgtcat cggaccaaaa
     1261 catatcttac ctacagatgt aaaaacgatg cctcatcctg gtttccctac agatatgcaa
     1321 gctcaaatga cagctatcca attagttgca gaaggtacaa gtgtggtgac tgaaacagtg
     1381 tttgaaaatc gtttccaaca tttagaagag atgcgccgta tgaacgctca tgtcaaaatc
     1441 gacggaaatg tagcaatcat ggatggaaac catgaattgc aaggtgcaga agtatatgca
     1501 acagacttgc gggcagcagc agcattagtt ttagctggct tgaaagcaaa tggaatcaca
     1561 cgtgtgcgta acttgaatta tctagaccgt ggatattata atttccatat caaactacag
     1621 caattaggtg cagacgtcga acgtgtagac atggatcaaa cttctgctga aaaaacagca
     1681 caaacgattg cttaaggaag tggctgaatg agtaaccaac gatatatctt attaactttg
     1741 ataaagattt tagtggtgat cttattgctt atccttcttt ttgtggccgg aacgatgatc
     1801 ggatatggtg tcatcggtgg cggcaatcca tttaaagtat tccagccaag tttgtggatt
     1861 catattcgag acttttttca ttgataaata agaatcacag tggttctagt cgatatgaag
     1921 tgagccatga agcagaacat gataaaagaa aacagaaggg aacgttgacg ttagtcgcga
     1981 tccctttttt tagtaaaaga aaagaaggaa tctaattgat gaagaagata ttgatttatt
     2041 tagttagagg atatcagcgc tttatttcgc ctgcatttcc acctagctgc cgttattacc
     2101 caacctgttc caattatatg ataaaagcaa ttcaaaccca tggtgcgcta aaagggacgg
     2161 taatggggac tgcacggatc ttacgctgtc atccttttgt caaaggcggt atcgattatg
     2221 taccattgac attccgatta acgcgaaata agaaagataa aaaagaacca gattataaaa
     2281 aggttgtgaa aaatacgggt agcactgagc gataaagaaa aagaggaaat ttattgtcaa
     2341 agtaacaact ccgcaactac ttatatgggg gacaaaaaat gatcgaagaa ctaaacaaga
     2401 aagatttacc atggtccttg ttattagatg cagatcctga taaagaaaaa gttcaagtat
     2461 atgtttccag agggagtggc tggatatgga aagaaaaaga aaaaacaata ggtgtactga
     2521 tctatgtggc aagggaaaaa gaatacgaaa tcgtcaatgt agcagtaacc ccaacgtatc
     2581 aaggaaaggg gattggcgga aaattacttg agacagcttt tcagaagctt tcacagctag
     2641 cttcaaacca aactcggatc attatacgta ctggcactac tagtagcgct gcgttacacc
     2701 tctatcaaaa aatgggctat gtggagattg gtcgagtcaa agactatttt atccatcatt
     2761 actctgagcc catttttgaa aatggagatc aattaaggga tcaagtgatt ttagcaattc
     2821 acttacctaa aaatagcttt aactaataaa ctttcaattc gagaaaatgc tttcaaatgc
     2881 taaatagata cattacaata gctttagcaa acaaaaagga gaatattttt atgggaatat
     2941 tagtttttga ttttggtgga tcggctgtca aatatggttg ttgggatggc aaagagatta
     3001 aaggtaaggg acaatttgca acgcctgaat cttgggaaga aatgaaaacg caattatttc
     3061 aagtttataa aaaaatactc gtttcttttg aagtcgaagg aattggaatc agctctcctg
     3121 gagtagtgaa taatgagaaa caggtgattg agggaatcag tgcgattcct tatattcatg
     3181 gatttaatat tttccgagat ttggaaactc tgtttcaact cccagtaacg attgaaaatg
     3241 acgccaactg tgccggaatg gctgaatttt atgaaggtgc tgcccgtgat tatcaagatg
     3301 ttgcttttgt tgtggcagga actgggattg gcggggcgtt gttcacgaaa ggacaaataa
     3361 ataaaggggc acatctttac ggtggagaat ttgggttgat gttcttagat ggcgataaga
     3421 cattcagtaa acttggtaca gcggtacaga tggcttggcg ttattgtgaa cgcaaaggtc
     3481 tcgataaaaa tgcttatacc ggaaaagatg tctttgaatt agcagaaact ggagatgcaa
     3541 tagcaaaaga agaagttgag agtttttata cgtatcttac aaagggatta ttcagtattc
     3601 aattttcgtt tgatccagaa gtgatcgtat taggcggcgg ggtttctgca aaagaagggc
     3661 tcattgatga gatcaaaagc cgaatgaaga agctgacaga acaattcgat ctgcatgatt
     3721 tcgaaccgca gattttatta tgtgagtaca gaaacgatgc taatcttata ggtgcagcag
     3781 caaactatct cgctgtacgt caaggagaga attaagagct ttagagaagg tgcagcttgc
     3841 ataaaagaag agaatgaaat gaataggaga tttttaccta aggaatgttt tatttgctgc
     3901 agtatgataa aatatctgag aggtgaaaat gatgtcaaaa aaaaataaag atattgaagt
     3961 gcgtatagaa gaagtgaaaa aagatatcaa aggtaagaat tatgaagtca ctcagttatt
     4021 tatagggaaa aaaatgattg gtgagatctt agcctatggg ccaaaagaat atgaaatttt
     4081 ctttggtgaa gaagattttg gaaaagaaaa aagtcttgaa aatgcgatag aaacagtgat
     4141 tcgacactgg aatctgcacg aataaaaaaa tatcaaaaaa actttcaata aagggttgca
     4201 aaaatctgga aaattaggta ttataactaa gtcaggttga tacaaacctt tcggaggagt
     4261 agcgaagtgg ctaaacgcga cggactgtaa atccgttcct tagggttcag tggttcgaat
     4321 ccactctcct ccatttcatt ggggtatagc caagcggtaa ggcaagggac tttgactccc
     4381 tcatgcgttg gttcgaatcc agctacccca gtataccaca atcgtaagct ctcgttagtt
     4441 cgagagctct ttttttttgc tttgctacct tgttccttga agattctgct gaattaagat
     4501 agagttaagt taactacaag aattggaggg atccacatga aatggaaaga aaaagtagac
     4561 gaagcagctg aaaagttata tgatttggtc aaatcagaaa aatacaatat tgaagtgaat
     4621 attccgaaaa aaggcggaaa agcggtccag gtaaaatcaa aacgcccaac gaatcataca
     4681 aaaaaatgga tggctaaaaa ccgctaataa taacaaaaga tccataagtc ggcattttca
     4741 tcgattttag ggtcttttgt tattttctag gttgaacata tctaaaaaat tgtttctgac
     4801 aataggagta gggagaacga tgtgtgtcta aatcctctgt tgatggatag aaacctttat
     4861 ctttttcagt tgtgaatcag gtatatacca gttataatag aagaaacgaa aggacgggtg
     4921 tacgttatgt cgaatcaatt acctgtatat atacagattc atgaccaatt aaaaaatgaa
     4981 atcgaacaag gtatatggaa agtcggagac cgtcttcctt cagaaagaga attagcagtg
     5041 aaattcaatg tcagccgtat gacgttgaga caagcaattc aaaacttggc agatgaagga
     5101 atcttagaaa gaaagatcgg ttcgggtacg tatgttgcgc gagaaaaagt acaagaaaaa
     5161 atgtctggtg caacaagttt tacagaaatt atggaatcac aaaatcgagt accgtctagt
     5221 cggacaatct cttatttctt gacttcgcca agctcaagtg aaatggaaaa actaaacttg
     5281 agtaaagatg acacgatctt gcgaatggaa cgtattcgtt tcgcagatga tgtccctatt
     5341 tgttttgaag ttgccagtgt tccacaaaag ctgatcgatg gctacagcaa agcagagatt
     5401 actgaatcgt tgtatcgcac gctagaagaa aaaggcggga aaaagatcgg tccagcgaat
     5461 caaacgatta ctgctgtgtt ggcttctgag aaaattgctg actatttaga ggtaaaacga
     5521 agagatgcag ttcttcgttt gcgccagatt tcttattttg aagacggtac gccgtttgag
     5581 tatgtgcgta cgcaatacgt aggaaatcgt tttgagtttt atttggaaaa ataaaaaaca
     5641 ggtgatccct gattccttat tagaaataaa agagaatcag aatcacctgt ttttatatat
     5701 gatcagttat cagttgctcg tgataagaaa cagaaccctc ttcaaattgg acttgtccgt
     5761 tcagcagctc aatgatggat tctttaaagt ggttagcact tttttcatct acagcacaga
     5821 tgacgctaac ttgatcagta tattggattt cttttataaa aaaatgttgg agttcaagat
     5881 aattctgtaa ttttcctagt tgcggatacg tgatcatcac agagatctcc tgttgcaagg
     5941 taccttctac gattccaatg tcagacaatg cttgagagac cgcatgagtg tatgctcgta
     6001 ttaatccgcc tgtgccgagt ttcgttcctc caaaatatcg agtgactact gcagctacat
     6061 tgatcagttg attttttttg aggacttcca acatcggtac gcccgccgtt ccacttggtt
     6121 ctccatcatc gctgcttcgc tggatttcat ttttttctcc aatgatgaag gcgctgcagt
     6181 tatggttcgc tttccaatgt tcttttttta tttcttgaat gaaatttttt gcttggtcct
     6241 ctgattctat tcgtctaaga gaacagataa agcgtgattt tttgatctca atctcacttt
     6301 gtccattttc ttttattgta cgatagcgct cgatcatctt gtcacctctt tttttcattt
     6361 tctttattca gtataaataa agttctaggt tgtttcaaca ctgtaacggt tgcgcaattg
     6421 ctgtagtatg cgataataaa gacaaaggca ggtggatctg gggatgcagg aacgaatgaa
     6481 aaagtacgat gcaattacgc attatttgaa gaacaatggc ggctctcaag taacgttgac
     6541 ctttacccaa tttgacgaac tgctgtttcc cagtaacgga cttcccaaaa cagcaaggga
     6601 aagtacagat tggtgggcaa atgattataa acaccctgaa aaaggtgcct atggctggat
     6661 aaatgcaggc tatgaagtag ttgtcatcaa tttggacaaa gaatatgtcg tgttcaataa
     6721 attagtgaaa tctagttggc tatttgatta aataaaccgc gtttagaaaa cgttgacaaa
     6781 tttctttctt tttatataat aaagtaacag acgcgaagaa aacgtttgcg tagtttgttt
     6841 taaaaaggag agaaaaatat ggctaaaaaa acaatcatgc ttgtatgttc ggctggtatg
     6901 agcacaagtt tactagtaac aaaaatgcaa aaagctgctg aagcaaaagg aatcgactct
     6961 gatattttcg ctgtgtccgc ttctgacgca gataacaatc ttgcaaataa agacgtggat
     7021 gtgttgttat taggcccaca agttcgcttt atgaaagctg attttgagaa acgtctggaa
     7081 ccaaaaggca ttcctttaga tgtcatcaat atggctgatt atggtatgat gaatggcgaa
     7141 aaagtgttag atcaagcaat cgcgctcata ggtgaataaa tagaacagta taactatcga
     7201 acaagcgatc caaaaaatag atcgcttgtt ttttcgtata tttttttagg gcgaataata
     7261 tgaatcattt ttggggtaga aggcttctga cgagagatat taaagcaata gactgtgagg
     7321 aggtaaattt accaaattat gagaagatcg cagcagtgga acgtttgggc aactggattc
     7381 tttgtcatcg ctgtggaatg aggacgtccg tcattgttgg acagcttgca gattacggtt
     7441 atttttgtac acattgtcta tatttagggt gatgcgacac tcaacaagat ttatatttgt
     7501 ttgatcagcc tgaagcaaaa cctcgagaag tcgtcttttt ttggacagga cagcttactg
     7561 aaaaacaaac ggaaatcgca aagagaatac tttgccattc agaaaaaaga catcatctta
     7621 tttgggctgt aacaggtgca gggaaaacag agatgcttta tcctatttta gtggaaactt
     7681 taaaagctgg aggaagagta gcgatttgta caccgcgagt cgatgtttgt aatgaattgt
     7741 ttttacgcta tcgttatgtt tttccagaag aaaaaatcac gttgctccat gggaatacag
     7801 caacggctta tacctttact tcttttgtta tctgtacgat tcatcagcta taccgttttt
     7861 atcggtcctt tgatttaata gtgatcgatg agatcgatgc gtttccttat aacggggatg
     7921 ctgggctagc tcacgctgtg caaacagcaa tcagatcaaa cggccgattc atctacttaa
     7981 gtgccacgcc tgatgagaag ttactaaagg aaatcaagca gacatttgag ctccacaaac
     8041 ttgccttgcg ctttcatcgg cgcttgcttc ctgaacccgt gcttgttttc atgaataatt
     8101 ggcgacaaaa atgtggaaac aaaaagaaaa tcaactcttt ggtgcggatc attcagcaac
     8161 taatcaaaga aaaccgtatc cttttatttt gtccaagtat tacgatgatg catcgtttaa
     8221 aaatcacact gcaagaagct tttccagaat atgagataac agatgtttct tcacaagacg
     8281 atcaacgggc aaagaaagtt cagaaaatgc gagaagcaat atacgagata ctgttaacca
     8341 caatgatcct agaaagagga gtcacatttg aaagaatctc tgtcatcgtt ttaggagcag
     8401 atcatccagt ttttactaaa tcctctttgg tgcaaatcgc aggaagagct gatcgtaaag
     8461 gtccttatac gaacagtcga gtctattttt tctatgaaga aaaaacttca gctattcgaa
     8521 aagcctgtca ggaaatcaaa gaaatgaacg aagaagggaa gcagatgctg tgagatgtag
     8581 ttgctgcggt aaagacatca ttcaaaattt aacattcagc gagatcatcg gagtgtcgaa
     8641 atctagactt cctcagacat gttcagtttg ccgcgcacaa ttccatttat tagaagcaaa
     8701 aggttgtgca ggttgtcaaa aaccaatcca tttgaaatac gaggagacga aaaagaaagc
     8761 aaatactagt ttcgtttact gcaacgactg tcaagaatgg aagaagaaat atcctgcata
     8821 tgattttcaa caccgcgcct tttttacgta cgatgaaaag atgcaggctt ggatcaatcg
     8881 gtacaagttt atgggagata tccgattagc agggactttt gcatataaat ggactcagat
     8941 aaaaaaagat tacccggcat atatttattg tccaatacct ttatctgaaa aaaggtggct
     9001 agaaagagga ttcaatcaag taagcgagat gttgaaagca gcaaaaattc cttttcagat
     9061 gctgctcaaa agagagcaac atctgcttgc tcaagcaaaa aacacgcgaa aggaaagatt
     9121 ggagatgcct cagccttttg agcttgccgt acctctttct aagatacaac ataaaaaaat
     9181 attgattatt gacgatgtct atacaacagg acagacgctt tttcatgcag cagattgctt
     9241 gcagaacgca cagccgaaaa tcatccgaac catttctttg gcaagatgaa tcagatgtgg
     9301 aaatttgata gcgatttaat ttgcaaataa cctagagttc gatataatag aattaagaag
     9361 agggaaagag tggtccttct ccttcttgat tgtggtagac gaaaggggta atttttatgt
     9421 ttagatataa tgtacgcggc gaaaatatcg aagtaactga agcgattcgc gactacgttg
     9481 agaaaaaagt aggcaaacta gaacgctatt tcagtgacgc acccgatgca acggcgcatg
     9541 tgaacttaaa agtttataca gaaaaaacag caaaagtgga agtaacgatc ccattacctt
     9601 atcttgtatt acgtgccgaa gaaacttctc cagatttata cgcaagtatc gatttggttg
     9661 ttgacaaatt ggaacgccaa atccgcaaat tcaaaacaaa aattaatcgt aaatcccgtg
     9721 aaacgggcat gaatactgca gatgctgctg ctttattcaa tgaagaggac gaaaacgaaa
     9781 atgattctga attagatatc gtacgtacga aacgcctttc attgaaacca atggatagtg
     9841 aagaagcagt cttacaaatg aacatgctgg gacataactt ctttattttt gaagatgcag
     9901 aaacaaatgg tacaagtatc gtttaccgcc gtaaagatgg aaaatacgga ctgattgaaa
     9961 cagactgatc agccttactt aaataacaac gaaaacttgc agcagctact gacagctgcc
    10021 gcaagttttt ttgagtttcc tcctctttta gatgaaatat gaataaatta tgaagttctt
    10081 actttaatac gcttaagata tttcaattat ctataactaa tgataaaatg aaaagtaaag
    10141 tctacatagt ctggataata cacagaagga aaaggagatt acacaacgca tggccaattt
    10201 gattcgttca cttatcgaaa acgataagaa agaactaaaa cgtttagata gcattgcaaa
    10261 aaaagttgaa gcatacgctg accaaatggc agcattaact gatgaacaat tacaggcaaa
    10321 aactgctgaa ttcaagggca gataccaaaa aggagaaaca ttagatcaat tacttccgga
    10381 agcttttgca gtcgtccgag aagcagcaaa acgtgtatta ggtttatatc cataccacgt
    10441 acaattgatg ggtggaatcg tgcttcacga tggaaatatc cctgaaatgc gtactggtga
    10501 aggtaaaacc ttgaccgcaa cgatgccagt atatctaaat gctctgactg gcgaaggggt
    10561 acacgtagtt accgtcaatg aatatttagc aacccgtgac tcgacggaaa tgggcgaact
    10621 ttataatttc ttaggattaa cagtggggtt gaatatcaac tcaaaatctt cggatgaaaa
    10681 acgcgaggct tataattgtg atatcactta tagtacgaat aatgaattag gatttgacta
    10741 cttgagagac aatatggtcg tttaccgcca tcaaatggta caacgtccgc tgaattatgc
    10801 cattgtcgat gaagttgact caatcttgat tgatgaagcg agaacgccgc tgatcatttc
    10861 agggcaagca gaaaaatcca cagctttata tacaagagca gacaacttcg tgaaacgttt
    10921 gaaagaagaa gaagattata aaatcgatgt acaatcaaaa acaatcagtt taaccgaagc
    10981 agggatcgaa aaagcagaag aaacattcgg tttggataac ttatacgaca ttgaaaatac
    11041 tgcattgacc catcacttgg atcaagcatt gagagccaac tatatcatgc ttttagatat
    11101 cgattatgtt gtccaagacg gaaaagtact gattgttgac cagttcactg gtcggatcat
    11161 ggatggacgc cgttattcag atggacttca ccaagcaatc gaagctaaag aaggcgtaga
    11221 gatcgaagac gaaacgaaaa ccatggcgac gatcactttc cagaactatt tccgtatgta
    11281 caagaaactt gcgggaatga ctggtacagc taaaacagaa gaagaagaat tcagagaaat
    11341 ttataacatc caagtatacc agattccgac aaatcgtccg gttatccgtg atgatcgtcc
    11401 agatttgctt tacccaacat tacaaagcaa gttccacgct gtcgtgcaag atatcaaaga
    11461 tcgctaccgc aaaggtcaac ctgtgttagt cggaactgtt gcggttgaaa catctgagtt
    11521 attatcagat atgctgaatc aagaacgtat tcctcatgaa gtgctgaatg cgaaaaatca
    11581 ctttaaagaa gcagagatca tcatgaatgc tggtcaaaaa ggtgctgtga cgattgctac
    11641 caacatggct ggtcggggaa cagatatcaa gttaggactt ggggtaagag aacttggtgg
    11701 tctagcagtt atcgggacag aacgacatga atctcgtcgt atcgataacc agcttcgagg
    11761 acgtgcagga cgtcaaggag accctggtat gtcacagttc tacttgtcat tggaagatga
    11821 tttgatgaaa cgattcggtt cagaacgaat caaagctttc ttagatcgga tgaagatcgg
    11881 tgaggaagat gctgttatcc aaagcaagat gctgacgaaa caagtagaat ctgcacaaaa
    11941 acgtgtagaa ggaaataact atgacacacg taaaaacgtc ttacaatacg atgatgtgat
    12001 gcgtgaacaa cgtgaagtaa tctataaaca gcgacaagaa gtaatcatgg aagaaaaaag
    12061 cttatccaag ccactaatga acatggtcaa acggacaatc agtcgtgtag tagatgcgca
    12121 tacacaatta gagaaagaaa attggaattt ggaaagtatc atcgattttg ccggcagtac
    12181 tcttgtccat gaagatagca ttactcttgc agatatcgaa ggaaaaacag ctcaggagat
    12241 caaagagtat ctaaacgaac gagcacaaga agtatttaat accaaagcgg ctcaactaaa
    12301 tggtccagag caactgttgg aatttgaaaa agtcgtgatc ttgcgtgttg tggactctaa
    12361 atggacagac catattgatg caatggatca attacgtcag tcaatcggct tacgtgctta
    12421 tggacagaac aatccattag tcgaatatca aacagaaggc tataagatgt ttgaagatat
    12481 ggtaggcgcc atcgagtatg aagtcactcg aatctttatg aaagctgaga tccgtcaaaa
    12541 cgtacagcgt gaacaggttt ctcaaggaac agcttctcac tcagaagacg gagatgccaa
    12601 agaaaatagt aatactagcg cgaaaaaaca gccaatccat gtgaataagg tcggaagaaa
    12661 tgatccttgt ccttgtggaa gcgggaaaaa atataagaac tgtcatggaa aaaatgcaaa
    12721 ctaatttctg acagcaggat tggtgagaca aattcttttt ttaagaattc gtctcacctt
    12781 ctttctgtta tttgctgatt ctgttagact agatataatg aaaaaagtat agtgaaagaa
    12841 ggaaaaaaca tggaaatatc cgaaattcga aatctcctga cagaaatgca ggaaaaggtc
    12901 acaagtttca ggaggtctct ttgacttaga tcagctggaa gaagacatcg cggaagcaga
    12961 agcaaaaatg gctgaacctg gtttttggga tgacagcgaa gccgcacaaa aagtgatcag
    13021 cgaaaataac gctaataaag aaacctatga ccaattccat tctcttgccg aagaactaga
    13081 agaaatcgaa ttgatggtgg agatgctgca agaagaacct gatgcagcaa tgcaagaaga
    13141 agcagaaaca cgtatcaatg cattagatga aaaaatgaag acgtatgaat tatctatgct
    13201 gttagacgga ccttatgatc gaaacaatgc gatcgtcgaa ttgcatccag gggctggcgg
    13261 aacggagtcc caagactggg gcagcatgct tttacgtatg tatacacgtt gggcagagca
    13321 gcatggctat caagtagaaa cactagatta tcaagcaggt gatgaagcag ggatcaagag
    13381 tgtgaccctg ctgattaaag gacataacgc ttttggttat ctaaaatcag aaaaaggtgt
    13441 tcatcgcctt gtacggattt cgccttttga ctcagcgaaa cgacgtcata cttctttttg
    13501 ttcggtagat gtgatgccag agcttgatga aacgatcgat atagaaatca atccagatga
    13561 tttgaaaatc gatacgtacc gagcaagtgg tgcaggtggt cagcacatca ataaaacaga
    13621 atctgctgta cggatcactc acttgcctac aggaacagta gtagctagtc aggcacaacg
    13681 ctcacaattg aaaaaccgtg agcaagcgat ggggatgtta aaagctaagc tttatcaatt
    13741 agaagtggaa aagaaagaac aagaagcagc tgcacttcga ggagaacaaa aagaaatcgg
    13801 ctggggttca cagatccgtt cttatgtttt ccatccctat tctatggtaa aagaccatcg
    13861 gacaaacgta gagacaggaa atgtccaagc agttatggac ggtgaccttg atttatttat
    13921 tgacggctat ttaaaaatgc atctacaata agaacccatt gttaaattga aataaaattg
    13981 taagattttg caagcatgtt gaaacattgc catgctataa tagctaaaga ctgaaaaaga
    14041 tatggagaga acgccatgat tgaaatgaag gatgtaatga agaagtactc aaatggtacg
    14101 accgctatcc gcaatctctc gattgtcatc gaacaaggag agtttgtcta tgtggttggt
    14161 ccgtctggag ccggtaaatc tacattcatc aaattgatgt atcgagaaga aaaagcttca
    14221 aaaggaactt tgaacgtcgc aggtcatgat ctaatagcaa tcaaaaaccg cgaagttcct
    14281 tatctacgca gagaaatcgg cgtggtgttc caagactata aattattacc aagaaaaaca
    14341 gtatatgaaa atgttgcgta cgctatgcaa gttatcggca gaaaacctcg agatatcaaa
    14401 aaacgagtaa tggaagtgct ggaccttgtt ggtttgaaac acaaagttcg agtctttcct
    14461 agcgaattat ccggtgggga acagcaacgt gtctctattg ctcgggcaat cgtgaatacg
    14521 cctaaagtac ttatcgcgga tgaaccgaca ggaaatctgg atccagaaaa ctcatgggaa
    14581 atcatgaaat tattagatcg gatcaatgcc caaggaacta ctgtcgtgat ggctacacat
    14641 aacagtacga tcgtaaatac gattcggcac cgagtaattg ctatcgaaaa cggccgcatt
    14701 attcgagatc aagcggaagg ggaatatgga tacgatgatt agaacctttt tccgccattt
    14761 attagaaagt atcaagagtt tgaaacgtaa cggctggatg acagttgctt cagtcagtgc
    14821 ggtaacgatc acgttgactt tagtcggtgt attcatggca gttatcatga atgcaactaa
    14881 attagctcag gatatagaag gaaacgttga tgtatctgta ttcgtagata tcggtacaaa
    14941 agacgaagag atgaaaaagc tagaaaaaga attgaatgac ttagatcatg ttaaaaaagt
    15001 tgaattttca agcaaagaac aggaattgaa aaaaatccaa aacgaaatgg gtgattcctg
    15061 gaaattgttt gaaggtgaca ataacccgtt atatgatgtg tatgtagtaa gtgctactga
    15121 tccttcttat acaaaacaag tagcagaaga agcagcagat ttgaagaatg tttctcgttc
    15181 tgattacggt ggagcttcct cagatcggat tttccaaatc gctggtgcag ttcggacatg
    15241 gggattagtt gcagcggcat tgctgctgtt cgtagcgatg tttctcattt cgaacacgat
    15301 tcggatcacg attttgtcta gacagcgtga aattcaaatc atgcgtttag tcggtgcaaa
    15361 aaatggatat attcgctggc cgtttttcct tgaaggtggc tggatcggtc tgatcggtgc
    15421 aattcttcca attttgatca tcacatttgg ttatgcatgg tttttccaat tgatcaatcc
    15481 atcattatta cgttcccatt attcattgat tcatccacaa aatatcgttt ggaaaatcaa
    15541 tcttttaatg gtcggcattg gtgtgatcat tggttcactt ggctcgatca tttctatgag
    15601 acgtttcttg aaattctaat accacaatat aaataaaatg agaaagttgg acagtttcgt
    15661 tccagctttc tttttttatt ggctaggaga atagaaggaa gcggcttttt tccctttact
    15721 ttaaaaaaca acttgggtat tcttaagttg gtagaagaag aggtgaagcc gtgaaaatta
    15781 tcgttgacaa tttttttacg atccttttga ttatgaatat tttgctttcc tttatcatcg
    15841 tttttcgaga aagaaaggaa actgctcaaa catgggcatg gctgctcgtt ttgatgttca
    15901 ttccagttgt aggatttatt ttatatattt ttttaggaag agggatttcc aaagagaaaa
    15961 tctttgattt gaagatccaa gggaaaatcg gtaagaacct ggaaattgaa gaagacaaac
    16021 aggcattgat gcgagggctt tatcctcatc cgcctactgg acaagtagat gtgaaacaat
    16081 tgatctatat gctcacggta tttgaaagta cgctctatac gactaaaaat gaaatcactt
    16141 tatttacaga tggtcgtgaa aaattcgatg cgctgattga agatatcaag caggcagaag
    16201 accatatcca cttccagtat tatatttatc gcagtgatgc attaggtgaa gaagttcgag
    16261 atgcattgac agaggcggca agacgagggg taaaagtcag agtccttctt gatgcatggg
    16321 gttccacaca agtttcttcc agcttttttc agaatttgaa aaaagcaggc ggagaagtcg
    16381 catttttctt tcctctattt gttccgtata ttaatcctcg gatcaattat cgcaatcatc
    16441 gtaaaatcgt agttattgat ggggaaatcg gatatacagg tgggttcaat gttggaaatg
    16501 aatatctagg attggtaaag aaatttggtt attggcgaga caatcatttg cgtatttacg
    16561 gagaagcggt gtataccttg caaaaccgtt ttttgatgga ctggaattct cagcatacaa
    16621 aagaagtagg ctattctccc aaattttttc cgtccattca cactactggt gatatagctg
    16681 ttcaaatcgt gacaagcgga ccagataccg aacatgaaca aatcaaaatg acttatttga
    16741 aaatgatttc gttagccaaa cgggagatat tgatccaaac gccttattac ataccggatg
    16801 gatcgattca tgaagcactg aagttggctc ttctttcagg cgtaaaagtt catatccaaa
    16861 tacctaacaa accagatcat cttctcgttt actgggcaac gtattctttc gctgcagagc
    16921 tgatcgagta tggagcaagg atcgaaacat atgagaatgg atttattcat gcaaagacga
    16981 tgattatcga tggtggcatt gtttcagttg gctcagcaaa tatcgatgtt cgttcatttc
    17041 gcttggactt tgaggtcaat acactggttt atgatgaacg aatggcttca cgtgtaagaa
    17101 aagctttttt tgaagactcg aaaatttcta cgcatctcac aaaagaaatg tatgaaaacc
    17161 gaggaataat catcaagatg aaagaaggat tagcaagatt gatttcgccg ctcctttaaa
    17221 acataaaaag gacatgagaa ccatcaacag atggagatct cgtgtccttt tttaacgggg
    17281 ccatttctga gagtacgtca gaaatggaga aagcgtctcg catgagcgaa attaactttg
    17341 gggtatctct tgttttttgg ggaaagcaag aaataagcta atatatgcta ttaaaagaga
    17401 cacatttcaa agccagtata gc
//
LOCUS       DACBYO010000059        17390 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.059, whole genome shotgun sequence.
ACCESSION   DACBYO010000059 DACBYO010000000
VERSION     DACBYO010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.059"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..376
                     /locus_tag="IVD26_001921"
     CDS             <1..376
                     /locus_tag="IVD26_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tra protein"
                     /protein_id="HAP6079865.1"
                     /translation="INSNNKYACEYVLSFEREMRKMRAGVYFATQTPEEIIPKDSGSE
                     VADIIRNIFNLCTFKCFFNLDSALLNDIKKVLGNTITDTEIMLLPELEVGQAVVQTSS
                     EDTYLINFDPYPEQIERFDGGQ"
     gene            396..1547
                     /locus_tag="IVD26_001922"
     CDS             396..1547
                     /locus_tag="IVD26_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079866.1"
                     /translation="MDEKQNNSLVSSLAKHGIKKLSKKFGIVLKIKILIIIAVTLLTC
                     LTLGGVLIGTLDSFQTTSTRSSGSSAEIIGGNKPLSPEVLKWQKQVEKYAERYGISPL
                     VPYALAIMQVESGGNLPDLMQSSESAGLPVNTLKYEESIDQGLKHLSNVYNIAKSYGM
                     ENNFDGICQAYNYGVAYMHYLGKNKKEHTLETAEVYSKNVVAPSLGNTTGQTYSYVNE
                     VSIKYGKTYLYLNGGNFYYAELVKQFIGGSGSGAPANPSEFWKDMKVEMEKYQGWPYV
                     WGGKNPTTGFDCSGLTAYLYQVCAGITIDSYTVSQYNASERVSIKDAKAGDLIFFRGT
                     YGAPDFISHVGIYVNETTMYDSNSSGIGYHNWQDSYWQQHSPEIRRVKK"
     gene            1565..2215
                     /locus_tag="IVD26_001923"
     CDS             1565..2215
                     /locus_tag="IVD26_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAP6079867.1"
                     /translation="MINYTSTTKWKIMTLILISVVIFGGLFAMLNNKNKHDENKKLET
                     KIAELETKNEKLSSNINDLNASIQSATSSPKGEELSKEITDVASKFVELYPYYDIEKV
                     EDKKNNLLEIASKEVADSIVPEDMISSSKKTLETNSEDQKGEAYSSDPTFRSRYESAT
                     LYTNFVNAKQVQYFAEVNYETESSSGDTNNTVFIQFEVTNDNGKVQVSDYEIKYLK"
     gene            2231..3127
                     /locus_tag="IVD26_001924"
     CDS             2231..3127
                     /locus_tag="IVD26_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079868.1"
                     /translation="MKKRYSIHDNKNKNKKDKSQIDKVYRKTKGTKLYLGAIISFLSI
                     ALLIVLSPLVLGKSYDYQTVDLNNPMNISSSLNMYIDDMEINKEDGLFKLVLRYQDDT
                     KTKSLSNIKSDYKLNYITNKGNDSAKMKVVKLSDEYTVVYYQGLPKDFGVISVTIKPR
                     YVYPELEPSDDLKDKEIKFYAVDQDIKQNNKLIVESMSDLKKDNFTYQTKAIRAEIEL
                     ERDKINKLKLANEVVEKDIAKAEQELDFQTLEEQTDTKNEINSMKTTIENNKSQIEES
                     NKKINGYEEKINQLEKTASSFE"
     gene            3564..3851
                     /locus_tag="IVD26_001925"
     CDS             3564..3851
                     /locus_tag="IVD26_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079869.1"
                     /translation="MEVKIRGVDPQYIQEIDRKVKEIKRKTNRNFSRNDYFKMLIRQD
                     SEIDLINYKKAEFDLALDKMLVSNEELTASIVNLTEVYERLFNLLLSEGGR"
     gene            3854..4117
                     /locus_tag="IVD26_001926"
                     /pseudo
     CDS             3854..4117
                     /locus_tag="IVD26_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4254..4841
                     /locus_tag="IVD26_001927"
     CDS             4254..4841
                     /locus_tag="IVD26_001927"
                     /inference="COORDINATES: protein motif:HMM:NF019976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NERD domain-containing protein"
                     /protein_id="HAP6079870.1"
                     /translation="MSEMNWFLLLLGGMSLLVLIAIIIGEWGVEKSSKSNLQIAKKIK
                     KKCRYAKILIDIELPDYKKMWGGRSKVKVDLIVIHGVNVYVLHFVNVEGYVYGHEATK
                     IWWCVHKSKIKFMNPMEISYMESEIVKGIISEGTEIIPIVVFPDGTNLNYINVIANDI
                     KIIYESQVVEYICSKKANVSKRNTQKLYTILQNAN"
     gene            4904..6424
                     /locus_tag="IVD26_001928"
     CDS             4904..6424
                     /locus_tag="IVD26_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079871.1"
                     /translation="MAEHFFNRKSASIILKAKFETGKSSKKNHMVELQKFVDYIARQE
                     AIRKDNIDHEYSKDELDELSRIEKALSIMEKESDQPVIKDIMQMDKYIDYMTRKKAIL
                     ENKDNEIVNGAFSNSKRYITQKDVKKIKESVIEAKNNDSVMFQDVISFDNDFLEREGY
                     YDPKTNQLNENILYEATKSMMEKLKEKEGLVDPFWFATIHRNTEHIHIHVTSMERQNT
                     REMMEYEGVLQARGKRKQSTLDDMIFKFGNKMIDRTNEFEKISKLRKDVPLEIKESVR
                     NTLLQVCIDNNSNYNTELEKYLAELKKEIPSNTRGYNELSKETKEKIDHVTDYLTKDN
                     PKRHEYDNMTRTIDQLYQETYGKRYTPEKFYEDRRVDLNARMGNAVVSQIKKIKQSEE
                     IGISGEELKKHLNNNALRLQVKHNDIDLKFKTEAGRYRYEKLVEKQSKSKEEQEKRIQ
                     NYKKRQMKFQNKKDLRQIERAINDDLHMYRAKKDFEQAQKMVEQEKIRQAYEFDFN"
     gene            6563..6811
                     /locus_tag="IVD26_001929"
     CDS             6563..6811
                     /locus_tag="IVD26_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP6079872.1"
                     /translation="METITPTNLRKDMFKVLKEVANSNSEVEITMNSKNGLNDGIIMV
                     SKREWDSLQEELYLQRTGTLDHVFNLMENENDDDFEVV"
     gene            6813..7100
                     /locus_tag="IVD26_001930"
     CDS             6813..7100
                     /locus_tag="IVD26_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP6079873.1"
                     /translation="MVSDWQVKVHKDVLKKQIPLLRSVGLISDYEDIIDVLKKNPYEN
                     IRSREKLNPRNKQIFSMRINSKHRVVYTIEKEKHLVKVWSAWSHYEKGIPK"
     gene            7178..8188
                     /locus_tag="IVD26_001931"
     CDS             7178..8188
                     /locus_tag="IVD26_001931"
                     /inference="COORDINATES: protein motif:HMM:NF022432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HAP6079874.1"
                     /translation="MNGKKYAKIVKKVKGLLAIAKDENKDEESQSAFLMAQRLMIQYD
                     IDKADVLEEGEEAEPIGEESVTVYKKLFWWERTLGQIIAKNFRVKMFYNSKRKNGDQR
                     KKSKVVFYGFGKDLELAKEMYILAYEVLLYHSQKYINRWYEDEGIARERYLTESIKSS
                     YIRGFLGGLEARFEEQVAILTKRYEVMVLIPKEVEESYKDYSKEFGVYNSKIPPVTVG
                     NAYSRGYEEAKKVDFTQKTVGTDYSSLVDRYIRFNEGGTRGLIAEVISISENQLNLLI
                     MNTVSSGFSTSNPCFYSWVIHAEHDFELLHLTDDSVRLFIDYKNNNNYKKQIAELITE
                     LR"
     gene            8334..9173
                     /locus_tag="IVD26_001932"
     CDS             8334..9173
                     /locus_tag="IVD26_001932"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079875.1"
                     /translation="MKLKSLGFLGLFVGCVIGLTACSQAESSKKSSDKEIAFAKVAKT
                     DEQNLWFLIEGDQTAKTPIEQDAKIDSVIVTKNGKYEMFKTEVGNLSLSDVSTMSDDE
                     IIENAEKYDQEKFENKLQSDTNDYESILQSAKEELTTEQGREFSDKSKIKELEEKIPL
                     LESDMAKLKSIEYQAPKWKEISVEINKGNDGEKAKNEIISLSYNYLSSPIWSFSNFKE
                     LSSEGEKVELIDNSKKLELAVPVAFAEVNKKIFTGYTNKNMETILVKQVHNKDQKMVL
                     DEE"
     gene            9317..11701
                     /locus_tag="IVD26_001933"
     CDS             9317..11701
                     /locus_tag="IVD26_001933"
                     /inference="COORDINATES: protein motif:HMM:NF024986.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP6079876.1"
                     /translation="MAYRKGVWQPKSKEEKQKELDELIELSNKKIEEYRADPKDMIEF
                     AKFMSKIHNYSPLNLSLIDEQFEGAIAVGSYKMWSEQGFSVRKGEKGIGIYTHAPVTI
                     FIDEEGKEKTLREATAEEKKKIKSGELSSRRIEHFKKGYVFDVSQTTATEEDLPKIFP
                     NRVWNFKVDEETNLDQLERGVDTLANELGISIKDMRESMVGELGSARGAYFQYVDGTE
                     EIALNFRNSRTQNIATSIHELAHKKMHNRLEKGASYPTEIKEFQAELTSFVVCNNYGI
                     DTSDFTIPYVANWTKNNEKINSKEFRSILGDIKSTALEFIESLDRSIIEQREIMSVEK
                     DYEKKTSNEAQSALKNSFANDGKEVEKKNKIFENQVFDRDSYIFFKNGNFDGYRFVDC
                     TFDKVNMSNSSFKNTVFEKCNFEFANMENNDFTEMSMYDSTIHGGSMRNSNLKNSTIW
                     GTKIDYFNMSNVNLLSTTFEDVDFSKIKIGQSIQNLDCANFYLSGATAEESKVYQQIN
                     LEKLNRINFNSEFNPDTIKLPFREYFSDPECPEREILRSYFEGMIEFYKEKNPQTEIK
                     VVYREYDVTAKIGKNYATYMSDVKQFDICDMYGVTAENTSIDENDHLILDRTPENCDY
                     VEAFIHETIRAESLEKQQIQKSEVVATEGDVYHFQKSELPTPLKVIATEEAVYNLSDS
                     AKQYYDLKEWSEEFTAQSEIDNVEQLLSCNEAEEFYEKHKQEIENKVDDFEKATGIDF
                     RSQLSESNYQSQVATLAYKIVAVELKNEIEESQFEIPLNSKLKKEELSLSYEME"
     gene            11764..13125
                     /locus_tag="IVD26_001934"
     CDS             11764..13125
                     /locus_tag="IVD26_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079877.1"
                     /translation="MSKFDHFSLEYKGLNGTADGFGIYLTPNKDMASMYAEQTKKLGY
                     IYEVTADLEKPLSTDELTITDKELSKIIDILQESNNILNDFNDVDYYGEKVVKREAIA
                     MLKENDNDVDLINEIANTTGDTEKTAEALYNVGHYTHIVANERLLQEDTVVVVLQPER
                     INIERVQDLNKELDVPAITENSHSGDKEKLSNQEEAVRLFWKGVLEQNRSFDFVGVDS
                     NGTTLHSGTFVPDPQDRADSWLMYFDNQGEMIKQYIMSIDEIEEFKAGKKDEFMSQFP
                     HGAPNIDYKILFHEENEFYWDWDEDIKGIKVPEVPIKDVIIKDFEQELETDRYYDKQA
                     WQERIEYLNSNDPSAILRFSLDEDVEEFYKSHSDEIEDKLSSMAEVLGVERNALINES
                     EATSEVDYKRYASIMAYKIGMDEINNDIENGTFKIPAMSEETENRILTVRNMESKQTF
                     EME"
     gene            13423..14439
                     /locus_tag="IVD26_001935"
     CDS             13423..14439
                     /locus_tag="IVD26_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3991 domain-containing protein"
                     /protein_id="HAP6079878.1"
                     /translation="MKISELKKIKIVDFCAENGIELTQDSREYYRLAEHDSCVISDRK
                     NLFKWNSRNIGGDIFNFIQEYYDCSFKEAKEKLLNSDYDIRENDNQYIKEPFTYNVSN
                     EQTVFKSRRYLINERRISKELIDDLITQGLIREDKRSNVLFIWKKNEEIVGCTEQGTT
                     AKFNQKKQKNITWKKIQENSEVNYGFKLTYGKPKSIYFFESEIDMLSYITQKPDKAQN
                     ATFISMNGLKKMTILQAVTDHFNEFKRLPESVVTCVDNDEAGRTFFDTEFKGKGIGRT
                     GIGVTEVKADFPKRNGFDWNDNLTKGKEIIQKMNDHDISKLKVFCEIKFSKTVQNNYE
                     VSNL"
     gene            14461..14820
                     /locus_tag="IVD26_001936"
     CDS             14461..14820
                     /locus_tag="IVD26_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079879.1"
                     /translation="MAETIAILSDSLLDLDKKSTDYMIIEEQLKNGNPEFNETEKALY
                     IELSKEKAFKLISILFEIIERYGLTYYQVWKDKNEKGEYTKGISVEAIRDKYSISIRA
                     VKPLLGSIADWGPILNV"
     gene            14969..15139
                     /locus_tag="IVD26_001937"
     CDS             14969..15139
                     /locus_tag="IVD26_001937"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079880.1"
                     /translation="MSNKIRIGIMIRGIEVRSKEEVEGVVLNVYDHIVIVFPKQGSPA
                     VVRKKDISAIFN"
     gene            15276..15467
                     /locus_tag="IVD26_001938"
     CDS             15276..15467
                     /locus_tag="IVD26_001938"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079881.1"
                     /translation="MSEETRELKEIYGKIKRMSIDDIHEALKTAETEEERELYLNMTS
                     FIMQMEQKKILKRKEKVHG"
     gene            15460..16407
                     /locus_tag="IVD26_001939"
     CDS             15460..16407
                     /locus_tag="IVD26_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP6079882.1"
                     /translation="MDDNLHYVVVGGVNGAGKSTIYEFDTIRIEGLKTDRINADEILQ
                     RNGGNWKNTTDVAKSMRQVVKDIKQHFEDRKSFHHETTFAGNTRPHEKRLFMAKSLGY
                     NTSLIYVGLESPELAIDRVKRRVQEGGHGVDDGIVMDRYYKSLENLSKLEKYFDNVTL
                     FDNSRLFQEIYVKKDHVVVANRSQIYNWVPETIKEKNVEKSIEQEIITSYTNKNKGYS
                     ELEKDYSSELGTLKIFQDKEYLDGFYNRHKNEISERVLGLSISIGTSSENLLGDNPKQ
                     KATELAYKMCLGNFLEKFEEKLLKTKNVDRVSEWDREIE"
     gene            16586..16903
                     /locus_tag="IVD26_001940"
     CDS             16586..16903
                     /locus_tag="IVD26_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079883.1"
                     /translation="MKNYASRKFIHLKPIKELSMNGNEYNDYKSLFVKDTPIGGIRMK
                     NMPDFRLIEVNNLGIVEYYLERLDEAVNLSIQQNGEEHILTVVLKDLKNRLESEAEFF
                     YED"
     gene            17066..>17390
                     /locus_tag="IVD26_001941"
     CDS             17066..>17390
                     /locus_tag="IVD26_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6079884.1"
                     /translation="MKFGGHFLNKKQDQEYYIEKLEKENLELKERIRYYESKFHKRSD
                     CMKPNLIETGKRIKSIRSNLGMTMEQFAILTDSSNTSAVNNWERGYNLPNKTKLKKIA
                     ILGNTT"
BASE COUNT         6889 a         2039 c         3484 g         4978 t
ORIGIN      
        1 tattaattct aacaataagt atgcttgcga gtatgtccta agttttgagc gagaaatgcg
       61 taaaatgcga gcaggggttt acttcgctac gcaaactcct gaagaaatta ttccaaaaga
      121 ctcaggttct gaagttgcgg atattattcg gaatatcttt aatttgtgta ctttcaaatg
      181 tttcttcaat ttagattcag cgctactaaa tgatattaaa aaagtcttgg gtaacactat
      241 tacagacaca gaaatcatgt tgctaccaga attggaagtt ggacaagccg tagtacaaac
      301 gtcaagtgaa gatacttact tgatcaattt tgatccgtac cctgaacaaa ttgaacgatt
      361 tgacggtgga caataacttt ggggaggatt tgaaaatgga cgagaagcaa aataatagcc
      421 tagtatcgtc actcgcaaag cacggcatta agaagctatc taagaaattc ggaatagttc
      481 taaaaataaa aattttgata attatcgcag ttactttgct tacctgttta acattaggtg
      541 gcgtattaat tggaacgtta gacagttttc aaacaactag tacaaggagt agtggctcta
      601 gtgcggaaat tataggtgga aacaaaccac tttctcctga agttttaaag tggcaaaaac
      661 aagtagaaaa gtacgctgaa aggtatggta ttagtccact agtaccatac gctttagcaa
      721 ttatgcaagt agaaagcgga gggaatctgc ctgacttaat gcaaagtagc gagtctgccg
      781 gtttaccggt aaatacgttg aaatatgaag aaagtattga tcaaggtcta aaacatttaa
      841 gcaacgttta caacattgca aaaagttatg ggatggagaa taactttgat ggtatttgcc
      901 aagcgtataa ctacggtgta gcttatatgc attatctagg taagaacaag aaagaacaca
      961 cattagaaac agccgaagta tattctaaaa atgttgttgc acctagctta ggaaatacaa
     1021 caggtcagac atattcctac gttaatgagg tttcaattaa atatggaaaa acatatttat
     1081 atcttaacgg agggaacttt tattatgctg aacttgttaa gcaatttata ggtggaagtg
     1141 gaagtggagc gcctgcaaat ccttctgaat tttggaaaga tatgaaagtt gaaatggaaa
     1201 aatatcaagg ttggccgtat gtttggggtg ggaaaaatcc tacaacaggg tttgattgta
     1261 gtggcttaac agcttattta tatcaagttt gtgccggaat tacgattgat agttacacag
     1321 taagccagta taacgcaagt gaacgagtat caattaaaga cgcaaaagca ggggatctta
     1381 ttttctttcg tggcacgtat ggagcgccag atttcatttc acacgttggt atttatgtca
     1441 atgaaacaac tatgtatgac agtaatagta gtggaattgg gtatcataat tggcaggatt
     1501 cgtattggca acaacatagt cctgaaatac gtagagtaaa aaaataagca aaggggaaaa
     1561 caatatgatc aattatacaa gtacaacaaa atggaaaatc atgactttaa ttctgatcag
     1621 tgtagtaata tttggtggac tattcgctat gctaaataat aaaaataaac atgacgagaa
     1681 taagaagctg gaaacaaaaa ttgcggaatt agaaactaaa aatgagaaac taagtagtaa
     1741 tatcaatgat ttaaatgcaa gtattcaatc agcgacaagt tcacctaaag gggaagagtt
     1801 gagtaaagaa attacagatg tggcgtcaaa atttgttgag ctttacccgt attatgatat
     1861 tgaaaaagta gaagataaga aaaataatct attagaaatt gcttcaaaag aagttgcaga
     1921 ttcaatagtt cctgaagata tgatctcgtc tagtaagaaa actttagaaa caaatagtga
     1981 agatcaaaaa ggcgaagcgt attcaagtga tccaacattt agaagtcgat atgaaagtgc
     2041 cacgctgtac acaaattttg taaatgcaaa acaagttcaa tattttgcag aagtaaacta
     2101 tgaaacagaa tcaagtagtg gcgatacaaa taacactgtt tttattcaat ttgaagtgac
     2161 taatgacaat ggaaaagtgc aagttagtga ttatgaaatc aaatatttga agtaaaaaag
     2221 gggaatcaaa atgaagaaaa gatactcaat tcatgataat aaaaataaaa ataaaaaaga
     2281 taaatcacaa attgacaaag tttatcggaa aacaaaaggg actaaattat atttaggggc
     2341 aataattagt tttctatcta ttgccctttt aatcgtttta tcgccactag ttttaggcaa
     2401 atcatatgat tatcaaactg tagatttaaa caatcctatg aatatttctt cttcactaaa
     2461 tatgtacatt gatgatatgg aaatcaataa agaagatgga ctatttaagt tagttttgcg
     2521 gtatcaagat gacactaaaa caaaatcatt gagtaatatt aaaagtgatt acaagctaaa
     2581 ctatattaca aataaaggaa acgattcagc aaaaatgaag gtagttaaac tttcagatga
     2641 atatactgta gtttactatc agggactacc gaaggacttt ggtgtaattt cagttacaat
     2701 taaacctcgt tatgtttatc ctgagctaga gccttcagat gatttgaaag ataaagaaat
     2761 taaattttac gcagtcgatc aagacataaa gcaaaataat aagttgatag ttgaatcaat
     2821 gtcagactta aaaaaagaca attttactta tcaaacaaaa gcaattagag cagaaattga
     2881 attagaaaga gataaaatca ataagctaaa attagcaaat gaagttgtcg aaaaggatat
     2941 tgctaaagca gaacaagagt tagatttcca aactttagaa gaacaaacag atacaaaaaa
     3001 tgaaattaat tcaatgaaaa cgactatcga aaataataaa tcacagatag aagaaagtaa
     3061 taaaaaaatc aatggatatg aagaaaagat taatcagcta gagaaaactg caagtagttt
     3121 tgaataagaa agagttcatt ggacatttaa ttaattgaaa aattaactga taaaaataaa
     3181 aagagagtga ttggttacca ttaagttcgg taacaatctc tcttttttta ttttgcaaat
     3241 aaacaatgaa acagggtcta agccgttgta gttcaacagg gagtaaaaca ggggttagta
     3301 ggggtttata taaagggaca aaaaaggggt taataacagg gaaggaggag cattttagtg
     3361 ggggcatatt ttttatggct atttatttag gaaaccagtt ggcaccgcca acttcccacc
     3421 tatcaaattt gaaggtggga tcagtttccc cttatgctct ttcattaatt tattaggtgt
     3481 tggccttcag tgcttcaaaa aaagcaaggt atctgttata attattgtat atcagataga
     3541 taataattag gagatgatta tatttggaag ttaagattcg tggtgtcgat ccacaatata
     3601 ttcaggaaat tgatcgcaag gtaaaggaaa ttaaacgaaa aacaaatcga aattttagtc
     3661 gaaacgatta cttcaaaatg ttgattaggc aagatagtga aattgattta attaattata
     3721 agaaggcaga attcgattta gctttggata aaatgcttgt gtcaaatgaa gaattaactg
     3781 caagtattgt caatttaaca gaggtatatg aacgattatt taacttatta cttagtgaag
     3841 gtggtagata aaaatggctg atccatatat taaggtgtat tgttcagaag aaacaaaaaa
     3901 attgtttgat gatttttacg aaaagaataa agggagtctt ggaacaaaag ctaatatgtt
     3961 ccgtgtgatg gtttcaaact tgccactgtt agccagccaa tcaaatatta aattaaatga
     4021 tccggaaagt aacgaactta aagaaggaat gtcagaatta cagttgatga tagcgaatga
     4081 agtaatggaa aaattgaata agattgacaa aatggtagaa gcaatgttta tcaatggcga
     4141 aataaatgat actgaagcaa aaataataga atcaaaagag tcaattaatc aagagaataa
     4201 ttcggaatat aaggaaggaa tgttctttac ttcaaataga ttggggcgtt aatatgtccg
     4261 aaatgaattg gtttttattg cttcttggcg gtatgtcact gcttgtttta atagcgataa
     4321 ttattgggga gtggggagta gaaaaaagct cgaagtccaa tctacaaatt gcaaaaaaaa
     4381 ttaagaaaaa atgtcgttat gcaaagatat taattgacat tgagcttcct gattataaga
     4441 aaatgtgggg tggtcgaagt aaagtaaaag tggatttgat tgtcatacat ggtgtcaatg
     4501 tttatgtact tcattttgta aatgtagaag ggtatgtgta cggacatgaa gctacaaaaa
     4561 tatggtggtg tgttcacaaa tctaaaatta aatttatgaa tccaatggaa ataagttaca
     4621 tggaatcaga aatagtgaag ggaattattt ctgaaggaac tgaaataatc cctattgttg
     4681 tgtttcctga tggaacaaat ttaaactata taaatgttat agctaatgac attaagataa
     4741 tatatgagtc acaagtagtt gaatacattt gctcgaaaaa ggcaaatgta agtaaaagaa
     4801 acacacaaaa attatataca atattgcaaa atgcaaacta aaaaattcta atgtcaaaaa
     4861 cattaagaac gccggtagaa aattttttgt gggggagtga atcatggccg aacatttctt
     4921 taaccgaaag agtgcaagta taatattgaa agctaaattt gaaacaggaa aaagtagcaa
     4981 aaaaaaccat atggttgaac ttcaaaaatt tgtagattat atagctcggc aagaagcgat
     5041 taggaaagat aatatagatc atgagtattc aaaagatgaa ttagatgaat tatcacgtat
     5101 agaaaaagcg ctaagtatca tggaaaaaga aagtgatcaa ccagttatta aagatattat
     5161 gcaaatggat aaatatattg actatatgac tcgaaaaaaa gctatcttgg aaaataaaga
     5221 taatgaaatt gtaaatggag cttttagtaa ttcaaaaaga tatataactc aaaaagacgt
     5281 aaagaaaatt aaagagtctg ttattgaagc gaagaataat gattcggtaa tgtttcaaga
     5341 tgttatatcg tttgataatg attttttgga aagagaaggt tactacgatc caaaaacaaa
     5401 tcaacttaat gagaacatac tgtatgaagc aactaaaagt atgatggaaa agttgaaaga
     5461 aaaggaaggg cttgttgatc cattttggtt cgcaacaatt cataggaata cagaacacat
     5521 tcacattcat gtaacttcaa tggaacgtca aaacacacga gagatgatgg aatatgaagg
     5581 tgtgttgcag gcaagaggaa aaagaaaaca atctacatta gacgatatga tttttaagtt
     5641 tggcaataaa atgatcgatc gtactaacga gtttgaaaaa atatctaagt tgagaaaaga
     5701 tgttccattg gaaataaaag aatctgtaag gaatacactt ttacaagtgt gcatagataa
     5761 taattcaaat tacaatactg aattagaaaa gtatctagcg gaattaaaaa aggaaattcc
     5821 aagcaacaca agaggatata atgaactatc aaaagaaaca aaagaaaaga tcgatcatgt
     5881 tactgattat ttaactaaag ataatccaaa acgacacgaa tacgataata tgacaaggac
     5941 aatagatcaa ctttatcaag aaacttatgg aaagcgatat acacctgaaa agttctatga
     6001 agatagaaga gtagatttaa atgctaggat gggaaatgct gttgttagtc aaataaaaaa
     6061 aataaaacaa tcggaagaga tcggaataag tggagaggaa ctgaaaaaac atttaaacaa
     6121 taatgcgttg cgattacagg taaagcataa tgatattgat ctaaagttta aaacagaagc
     6181 tggccggtat cgttatgaaa aattggtaga gaaacaaagt aaatcaaaag aagagcaaga
     6241 aaaacgaata caaaattata aaaaaagaca aatgaaattt caaaataaaa aggatttaag
     6301 gcaaatcgaa agagcgataa atgacgatct tcatatgtat cgtgcaaaaa aagattttga
     6361 acaggctcaa aaaatggtag aacaagaaaa aataagacaa gcatatgaat ttgattttaa
     6421 ctaaatagaa tttggaggtt tttatgagta atttgaaagg taaagtagaa aaataatttg
     6481 atcattttgc ataataagta ttctaggtaa ttgactaaat tcaatatgta cgttataatg
     6541 tacataaaga gaggtgttta ctttggaaac tattactcca acaaatttaa gaaaagatat
     6601 gtttaaggtg ttgaaggaag ttgcaaactc aaactctgag gtagaaatta ctatgaattc
     6661 caaaaatggt ctaaacgatg gcattatcat ggtttctaaa agagaatggg atagtttgca
     6721 ggaagaactc tatttacaaa gaactggtac attagatcat gtatttaatc tgatggaaaa
     6781 tgaaaatgat gatgactttg aggtagttta atatggtatc tgattggcag gtgaaagtgc
     6841 ataaggatgt tttaaagaag caaattcctt tactgagatc agtcgggtta atatctgatt
     6901 atgaagatat tattgatgtc ttaaaaaaaa atccgtatga aaacattagg agtagagaga
     6961 aattgaatcc tcgtaataaa caaatttttt ctatgagaat caacagcaaa catagagttg
     7021 tttatactat agaaaaagaa aagcatttag tgaaggtttg gagtgcatgg tcacattatg
     7081 aaaaagggat acctaaatga caactaagaa aagggaacta aattgttccc ttttcttaga
     7141 aatctaatga ctacaagtag acaaaaggag attgattatg aatgggaaaa aatatgcaaa
     7201 aattgtaaaa aaagtaaaag ggctactagc gatcgccaaa gatgaaaata aggatgaaga
     7261 gagccaatca gcgtttctaa tggctcaaag attgatgatt caatatgaca tagacaaagc
     7321 agacgtgcta gaagaagggg aggaagcaga gcctattggt gaagagtcag tgacggttta
     7381 taaaaaactt ttttggtggg aacggactct tggtcaaatt attgcaaaaa attttagagt
     7441 gaagatgttt tataattcta aaagaaaaaa tggtgatcaa cgcaaaaagt cgaaagtggt
     7501 attttatggg tttggaaaag atttagaatt ggctaaagaa atgtatatat tagcttacga
     7561 ggtgttgctt tatcactcgc aaaagtatat caatcgttgg tatgaagatg aagggattgc
     7621 gagagaaagg tatttaactg aaagcattaa gtcaagctat attagagggt ttctaggagg
     7681 attagaagct cgatttgaag aacaagttgc tatacttaca aaaagatatg aggttatggt
     7741 tttaattcct aaagaggtgg aagaatcata taaagactat tctaaagaat ttggagttta
     7801 caattctaaa atcccgcctg taactgtagg aaatgcgtat tctagaggat atgaagaagc
     7861 aaaaaaagta gacttcacac aaaaaacagt gggtactgac tactcaagtc ttgtggatcg
     7921 ctatattcgt tttaatgagg gaggaactag aggactgatt gctgaagtaa tcagtatttc
     7981 agaaaatcaa ttgaacttat tgattatgaa tactgtttct tctggttttt ctacaagtaa
     8041 tccttgtttt tattcgtggg ttattcatgc agaacatgat tttgaactct tgcatttgac
     8101 agatgattcc gtgcgacttt ttatagatta caaaaacaat aataactaca agaaacaaat
     8161 agctgaattg ataactgaat tgaggtagcg gagtatctgc tatctctttt tattctaaaa
     8221 taactcttta aatcattgcg cccaaaaggt actataagta atgaagagta tattcattta
     8281 tcagaatatg atattataaa tatatatcgg atggataaaa agaggtgtaa gtgatgaaat
     8341 tgaagagtct aggattttta ggattatttg tcggatgtgt aattggttta actgcttgca
     8401 gtcaagcaga gagtagtaag aagtctagcg ataaagaaat tgcttttgct aaggtagcaa
     8461 aaacagatga acagaactta tggtttttga ttgaaggtga tcaaacagct aagacaccaa
     8521 tagaacagga cgcaaaaatc gactctgtca ttgttactaa aaacggaaaa tatgaaatgt
     8581 ttaaaacgga agtaggaaat ctatcattga gtgatgtttc tactatgagt gatgatgaaa
     8641 tcattgaaaa tgcggaaaag tatgatcagg aaaaatttga aaataaactt caaagtgata
     8701 caaacgatta tgagtctatt ttacagtcgg cgaaagagga attaacaaca gaacaaggaa
     8761 gagaattttc tgacaaaagt aaaatcaaag aattagaaga gaaaatcccg ctgttagaaa
     8821 gtgatatggc aaaattgaaa tctatagaat atcaagctcc taaatggaaa gaaatttctg
     8881 ttgaaattaa caaaggaaat gacggagaaa aagctaaaaa tgaaattatt agtctctcgt
     8941 acaattatct aagtagcccg atttggagtt tttcaaattt taaagagtta tccagtgaag
     9001 gagaaaaagt tgagctgatt gataatagca agaaattaga attggcggtt cctgtagcgt
     9061 ttgctgaagt gaataaaaaa atatttactg gctatacaaa taaaaatatg gaaacaatac
     9121 ttgttaagca agttcataat aaggatcaaa aaatggttct agacgaagaa tgatatatgc
     9181 agtaaagagg ataaaatcaa tgattatcct ctttttttag tgcttaattt caatagattt
     9241 aatagcgata ttaatgtcta tctgatataa taaaactatg gtggataaca ccaaaataaa
     9301 gaaaggagaa gttcaaatgg cttataggaa aggggtctgg cagccaaaat cgaaggagga
     9361 aaaacaaaag gaattagatg aactaattga actgtctaat aagaaaattg aagagtatag
     9421 agctgatcca aaagatatga tcgagtttgc taaattcatg tcaaaaatcc ataactatag
     9481 tcctttaaat ttatcgttaa ttgacgaaca atttgaagga gcgatcgctg taggaagtta
     9541 taaaatgtgg agtgaacagg gatttagtgt taggaaagga gaaaaaggga taggcattta
     9601 cactcatgcg cctgtgacaa tattcattga tgaagaagga aaagaaaaaa cgctccgaga
     9661 agctacggca gaagaaaaga agaaaatcaa aagtggagaa ttatcaagcc gtcgtatcga
     9721 acatttcaag aaggggtatg tatttgatgt atctcaaact actgctactg aagaggattt
     9781 gcccaaaata ttccccaata gagtttggaa ttttaaggtt gatgaagaaa ccaatttaga
     9841 tcaacttgaa aggggtgtag atactcttgc taatgagtta gggatttcta ttaaagatat
     9901 gcgggaatct atggtaggag agttgggaag tgcaagggga gcgtattttc agtatgtgga
     9961 cggaacggaa gagatagctt tgaatttcag aaatagccgt actcagaata ttgctacaag
    10021 tattcatgag ctagctcaca agaaaatgca caatcgatta gaaaaaggtg ctagttatcc
    10081 tactgaaata aaagaatttc aggcagaact gacctcgttc gttgtatgta ataactatgg
    10141 tattgatact tctgatttta ctataccgta tgttgcaaat tggacaaaaa acaatgagaa
    10201 aatcaattct aaagaatttc gtagtatttt gggggatata aagtctacag cgcttgaatt
    10261 tattgaaagt ctggatagat caataattga acaaagagag ataatgagtg ttgagaaaga
    10321 ttatgaaaag aaaacttcaa atgaagcaca aagtgcgcta aaaaattcct ttgccaatga
    10381 tggtaaagag gtagaaaaaa agaataaaat atttgaaaat caagtgttcg atcgagacag
    10441 ttatatattt tttaaaaatg gaaattttga cggttatcgg tttgtagatt gtacgtttga
    10501 taaagttaat atgagtaaca gtagctttaa aaatactgta tttgaaaaat gtaattttga
    10561 atttgctaat atggaaaata atgattttac tgaaatgtcc atgtatgatt caacaattca
    10621 tggtggaagt atgagaaatt caaaccttaa aaattcgact atttggggaa cgaagattga
    10681 ttattttaat atgagtaatg tcaacttgtt atcgactact tttgaggatg tagatttttc
    10741 aaaaattaag ataggtcaat caattcaaaa tcttgattgt gctaatttct atctaagtgg
    10801 ggctacagct gaagaaagta aggtctacca acaaattaat ttagagaaat taaatcgaat
    10861 taattttaat agtgagttca atcctgatac tattaagttg ccgtttcggg aatacttttc
    10921 tgatcctgaa tgtcctgaaa gagaaatatt gcgttcgtat tttgaaggca tgattgaatt
    10981 ttataaggaa aaaaatcccc aaaccgaaat caaggtggta tatcgagaat atgatgttac
    11041 tgctaagatt ggtaaaaact atgcaacgta tatgtcggat gtaaaacagt ttgatatttg
    11101 tgatatgtat ggagtcacag cagaaaatac tagtatcgat gaaaatgatc acttgatatt
    11161 agatagaaca ccggaaaatt gcgattatgt agaagcgttt attcatgaaa caattagagc
    11221 tgaatcatta gaaaaacaac agattcaaaa aagtgaagta gttgctactg aaggagacgt
    11281 gtatcatttt caaaaaagtg aattgccaac tccattaaaa gtgattgcta ctgaagaagc
    11341 cgtgtataat ttatctgatt cagctaaaca gtattatgat ttaaaagagt ggtctgaaga
    11401 gtttacagcc caatctgaaa tagataatgt ggaacaattg ctttcttgta acgaagcgga
    11461 agaattttat gaaaagcata aacaagaaat agagaataaa gtagatgatt ttgaaaaagc
    11521 aacaggaatc gattttagaa gtcagttatc tgaaagtaat tatcaatcac aggttgctac
    11581 tcttgcgtat aaaattgttg ctgtagaatt aaaaaatgag atagaagaaa gccaatttga
    11641 aatcccttta aattcaaaat taaaaaaaga agagctttct ttgtcatatg aaatggagta
    11701 aaaaagatgg aaaaaaataa taattatttg agagcaggaa agtatcagtt atttcatgga
    11761 agcatgagca aatttgatca ttttagtctt gaatacaagg ggcttaatgg tacagctgat
    11821 gggtttggca tttacctaac gcctaataaa gatatggcga gtatgtatgc tgagcaaact
    11881 aaaaaattag ggtatatata cgaggttaca gctgatttag aaaaaccgtt atctactgat
    11941 gaattaacaa ttacagataa agaattatca aaaattattg atattctaca agagtctaac
    12001 aatattttga atgattttaa tgatgttgat tattatggtg aaaaggtagt taaacgagaa
    12061 gctattgcaa tgctaaagga aaatgacaat gatgttgatc taattaacga gattgcgaat
    12121 accacagggg acactgaaaa gacggcagaa gcactttaca atgtcgggca ttatacgcat
    12181 atagttgcca atgaaagatt gttacaagaa gatacggtag tagttgtgtt gcaaccggaa
    12241 agaataaaca tagaaagagt tcaagactta aataaagaat tagatgtacc tgcaattact
    12301 gagaattccc attctggaga taaagaaaaa ttatctaatc aggaggaagc tgttagatta
    12361 ttttggaaag gtgtattaga acaaaataga tcatttgatt ttgttggagt ggattccaac
    12421 ggaactacgc tacattctgg tacgttcgtt cctgatccac aggatagagc tgatagctgg
    12481 ctgatgtatt ttgataatca aggtgagatg attaaacaat atataatgtc tatcgatgag
    12541 attgaagaat ttaaagcagg gaaaaaagat gagttcatgt ctcaattccc acacggagcg
    12601 ccaaatattg attataaaat tctctttcat gaggaaaacg aattttattg ggattgggat
    12661 gaagatatta aaggaattaa ggttcctgaa gtacctataa aagatgtaat tataaaggat
    12721 tttgagcagg agttagaaac agaccggtac tacgataagc aggcgtggca agaacgaata
    12781 gaatatctta attcaaatga tcctagtgct attctacgct tctctttaga tgaagatgtt
    12841 gaagagtttt acaagagtca ctcggatgaa atagaagata aattatcttc tatggccgag
    12901 gtgttaggtg tagaaagaaa tgcattaatt aatgaatctg aagccacttc agaagtggac
    12961 tataaaaggt acgcttctat tatggcttat aaaatcggaa tggatgaaat taacaatgat
    13021 attgaaaacg gaacgtttaa aatccctgct atgtcagaag aaacagaaaa tagaattcta
    13081 actgtaagaa atatggaatc taaacaaacg tttgagatgg aatagtaggt gagaagatgt
    13141 ttaaacaaat tgactttgag aaagtaatta gggctaatct catacctaat tccaattgcc
    13201 atgtttatat ttgcgaagat actcaaacag ccttccagtt agctctaaag tatgggaaat
    13261 atgtaaggac tcatataata agagaaaaaa gagacaagag agaaggtttt tggaaagtgt
    13321 acttgtcaga tggaggtaga tgtattttct gttcagagga ttatttctta caatctccaa
    13381 tagcttgctc atatttagga tttgccggtt aggtgagatt ggatgaaaat aagtgaatta
    13441 aagaaaatta aaatagtgga tttttgcgct gaaaatggta ttgaattaac acaagattct
    13501 agggaatact accgcttggc tgaacatgac tcttgtgtaa taagtgatcg aaagaatctt
    13561 tttaagtgga attcccgaaa tattggtgga gatatattta acttcataca ggaatattat
    13621 gactgttctt tcaaagaagc gaaggaaaaa cttcttaata gcgactatga tattcgtgaa
    13681 aatgataatc aatatataaa ggaacctttc acctataatg tatcaaatga acaaacagtt
    13741 tttaaatcaa gacgatattt aattaatgag cgtagaatta gtaaggaatt aattgatgat
    13801 ttaatcacgc agggattaat cagagaggat aaacgatcaa atgtcctttt tatatggaaa
    13861 aaaaatgagg agatagtagg atgtaccgaa caaggaacta cagccaagtt taatcaaaaa
    13921 aaacaaaaaa atataacatg gaaaaaaata caagaaaata gcgaagtaaa ttatgggttt
    13981 aaattgacgt atggaaagcc taaatcaatc tatttttttg aaagtgaaat tgatatgtta
    14041 tcgtatataa ctcaaaaacc tgataaagcc caaaatgcaa catttattag tatgaatgga
    14101 ctaaagaaaa tgactattct acaagctgtc acagatcatt ttaacgagtt taaaagactc
    14161 cctgaatcag ttgtaacttg tgtagataat gatgaagcag gtcgaacatt ttttgataca
    14221 gagtttaaag gaaaggggat aggaagaact ggcataggag ttactgaagt gaaagcagat
    14281 tttcctaaaa gaaatggttt tgattggaat gataatttga ctaagggaaa agagattatt
    14341 caaaagatga atgatcatga catttcaaaa ttaaaagtat tttgtgagat aaaattcagt
    14401 aagacagttc agaataatta tgaagtgagt aatctatagg aaaagtaggt ggataatttc
    14461 atggctgaaa caatagcaat actatctgat tcacttcttg atttagataa aaaatcaact
    14521 gattacatga taattgagga acaattaaaa aatggtaatc cagaatttaa cgaaacggag
    14581 aaagcattat atattgaatt atctaaagaa aaagcgttta aactgatttc tattctattt
    14641 gagataattg aaagatatgg attaacttat tatcaagttt ggaaagacaa aaatgaaaag
    14701 ggagagtaca ctaaaggaat aagtgtggaa gcgatcagag ataaatacag tataagtatc
    14761 agggcagtga agccattgct aggttctatt gctgattggg gaccaatttt aaacgtctag
    14821 ctaatatgct aggcgttttt ttgttgatga tttagaaact gagtaatagg aaaaattggc
    14881 gaatacctat tgactacaag tagacaataa aggtatactc caagtgtaga taaaagacta
    14941 caagtagtca gtgaacggag ggtataatat gagtaataaa ataagaattg gaataatgat
    15001 cagaggaatt gaagttagat caaaagaaga agtagaagga gtggtattga acgtttatga
    15061 tcatattgta attgtttttc ctaaacaagg tagtccagct gttgtgagga aaaaggatat
    15121 atcagctatt tttaattagg gaacagcata aatttcatta tgttgactac aagtagacaa
    15181 aaagttataa tagctatata aagtccgaga aaagaaaaat aattggtcta taaaggatga
    15241 tatttagaaa aagcgataag aatggagtga atcatatgtc tgaagaaact agagagttaa
    15301 aggagatata cggaaaaatt aaacgaatga gtatagatga tattcatgaa gctctaaaaa
    15361 ctgcagaaac tgaagaagaa agagaactct atctaaatat gacaagcttt ataatgcaaa
    15421 tggagcaaaa aaagatctta aagcgaaaag agaaagttca tggatgataa cttacattat
    15481 gttgtagttg gtggtgtgaa tggagctggg aaatcaacta tttatgaatt tgatactatc
    15541 cggattgagg ggcttaaaac ggatagaatt aatgcagatg aaatattaca aagaaatggt
    15601 ggaaactgga agaatacaac agacgttgct aagagtatgc gacaagtagt taaggatata
    15661 aaacaacatt ttgaagatag aaagtcgttt caccacgaaa ctacttttgc aggtaataca
    15721 agaccccatg aaaagcgatt atttatggcc aagtctttag gttataatac gtcactaata
    15781 tatgtaggac ttgaatcgcc tgagcttgcg atcgaccgtg taaaaagaag agtacaagag
    15841 ggcggtcacg gcgttgatga tggtatagtg atggatagat attataagtc gcttgagaat
    15901 ctttcaaaac ttgaaaaata ttttgataat gtaacactat ttgataattc acgtttattt
    15961 caagaaatat acgtgaaaaa agatcatgtt gttgttgcta atagaagtca aatttataat
    16021 tgggtacctg aaactattaa agagaaaaac gttgaaaaat ctattgaaca agaaattatt
    16081 actagttata caaacaaaaa taaaggatat agtgaacttg aaaaagacta ctcttcggaa
    16141 ttaggaacat taaaaatatt tcaagataaa gagtatcttg atggtttcta taaccggcat
    16201 aagaacgaaa taagtgaacg agtattgggt ttaagcatat ctattggaac tagttcagaa
    16261 aatttgcttg gtgacaatcc taaacagaaa gcaactgaac ttgcctataa aatgtgctta
    16321 gggaatttct tggaaaaatt tgaagaaaaa ttacttaaaa ctaaaaatgt agatcgtgtg
    16381 agtgagtggg atagagagat tgagtaggcg tatgttatgc ctactcttca aaaaaaacat
    16441 tgactacaag tagacaaagg tatataataa aagagtggaa gggttacaag tagtcaatga
    16501 atgtagctct ctatcaaacc aaaggatttc acgttgttaa catgaaagta taataaggga
    16561 agatatttct acaggggaga ttactatgaa aaactatgct tcacgtaagt ttatacactt
    16621 aaaacctatt aaagagttgt ctatgaatgg aaatgagtat aatgattaca aatcattatt
    16681 tgtaaaagat actcctatag gtgggattcg gatgaagaat atgccggatt ttcgattaat
    16741 tgaagtaaat aatctaggaa ttgtagaata ttatttagaa agattagacg aagcagtaaa
    16801 cttgtcaatc caacaaaatg gtgaagaaca tatacttaca gttgttctaa aagatttaaa
    16861 aaacagattg gaatcggaag cggaattttt ctacgaggat taatgtaaaa ggaattaaat
    16921 tctattgtta ttgcaattat ctaactattt ttatagttag ataattttat aaatcaaatg
    16981 taacgtaagg gtatacccta ttgtatcata tggtaaagta cagtataata aggtttggag
    17041 gtgtaacatt agggtgtaac acaatgtgaa atttggaggt cattttttga acaagaaaca
    17101 ggatcaagaa tattatatag aaaaattgga gaaagagaac ttagaactca aagagcgaat
    17161 aagatactat gaatccaaat tccataagag aagtgattgt atgaaaccaa atcttattga
    17221 aacaggtaaa agaattaaat caattcgttc taatttggga atgacaatgg agcaattcgc
    17281 tattttaact gattcttcta atacgagtgc tgttaataat tgggaacgtg gttacaactt
    17341 acccaataaa accaaactaa aaaaaatagc tatactagga aatacaacta
//
LOCUS       DACBYO010000060        16957 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.060, whole genome shotgun sequence.
ACCESSION   DACBYO010000060 DACBYO010000000
VERSION     DACBYO010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16957
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.060"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..1003)
                     /locus_tag="IVD26_001942"
     CDS             complement(<1..1003)
                     /locus_tag="IVD26_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6079885.1"
                     /translation="MLLNFKMTLTMLAFSLLVTGVILVSFFFLRNNLEGISIASTLGE
                     DVYFMEEGKTVQAETQMEASKSSNNQFMTISMIDKAYQDELFKYLPAMVLVICSAVML
                     LTFILWLVLRKIYSNQILAITRDLTFIDQVPKNTVKDEALNAAFNKLKDKFDGHLEDY
                     RRLNSYLTHEQKNAIAILRTNLEIERQHADQGNLMLLDRMTDSIDDILTLSNNSEDLS
                     TEVVDVSLICAEVCDAYKMNYPNLLFAFTEDQPTLIHGRDRWIYRAVSNLVDNAIKYG
                     EGKLVIVTISNQKGSVIIEVKDQGIGIPQEKQASIFSHQYRVHGLKQDGLPKTMDFRD
                     "
     gene            complement(994..1662)
                     /locus_tag="IVD26_001943"
     CDS             complement(994..1662)
                     /locus_tag="IVD26_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6079886.1"
                     /translation="MRVLVVEDNRELVLSVKKGLEQENISVDVAYDGESGEEKAFINS
                     YDGILLDLNLPKKDGLSVLQSLRAEEVESPVIIITARDEIEERAKGLDFGADDYLVKP
                     FELLELKARIRAVIRRYHGRALPQISIGALKIDPLGRRVSYQKTEVVLKPKEFDILLC
                     IAQRHPAVVSSEEISEHVYDEDFDPFSSVLRVHLARLKKKLAEAAEKEVLKTIRAKGY
                     QLCY"
     gene            complement(2118..3104)
                     /gene="lacD"
                     /locus_tag="IVD26_001944"
     CDS             complement(2118..3104)
                     /gene="lacD"
                     /locus_tag="IVD26_001944"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAP6079887.1"
                     /translation="MNEEKRQYIKQLCNEDGVIGALAIDQRGALKKMITKFKGSEAEE
                     SEIVEFKEIVSSQLTKYASSILLDPEYGLPAADVRAKNAGLLLAYEKTGYDASTPGRL
                     PDLLSIWSVKRLKEAGADACKFLLYYDVDEAEEINNQKHAFIERIGSECQAENLPFFL
                     ELVSYDANISDATSKEYAIKKPHKVNDMMKEFSDPRYGVDVLKVEVPVNMNYVEGYGT
                     DEVVYTKAQAANFFKEQAEATNLPFIFLSAGVKAELFQETLRFAKNAGSTFNGVLCGR
                     ATWADGVESYIVDGKEAAMEWMNTQGRKNIEELNAVLKETATPVEVLTSSLS"
     gene            complement(3117..4043)
                     /gene="lacC"
                     /locus_tag="IVD26_001945"
     CDS             complement(3117..4043)
                     /gene="lacC"
                     /locus_tag="IVD26_001945"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HAP6079888.1"
                     /translation="MILTITMNPSIDISYPLETFKLDTVNRVRNVRKTAGGKGLNVTR
                     ILKQLDTEVIASGLIGGFLGEEIKKDLTQNEIAHDFLPISGETRNCIAVLHDGKQTEI
                     LENGPVITEQEARAFLQHFEKLAVKAEIISFSGSLPEGLPADFYRQMLQVCQPKPVVL
                     DCSGTALREVLRGSVKPKLIKPNTEELAGLLGREISTELSDLKAALSDSMFDEIEWIV
                     VSMGGDGAFAKHHETFYCVTIPKIDVVNPVGSGDATVAGLTAAIQQGLSDEAVLKQGN
                     VLGMLNAQEATTGYVQLANYQKLYDQILVEKV"
     gene            complement(4056..4571)
                     /gene="lacB"
                     /locus_tag="IVD26_001946"
     CDS             complement(4056..4571)
                     /gene="lacB"
                     /locus_tag="IVD26_001946"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HAP6079889.1"
                     /translation="MKIAIGCDHIVTDTKMAVSDFLKSKGHEVLDMGTYDFTRTHYPI
                     YGKKVGEAVTSGEADLGVCLCGTGVGINNAVNKVPGIRSALVRDMTTAIYAKEQLNAN
                     VIGFGARITGEFLICDILEAFINADYQETEENKKLIAKIDHVEKASDKQSDPHFFDEF
                     IEKWDRGEYHD"
     gene            complement(4590..5018)
                     /gene="lacA"
                     /locus_tag="IVD26_001947"
     CDS             complement(4590..5018)
                     /gene="lacA"
                     /locus_tag="IVD26_001947"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HAP6079890.1"
                     /translation="MRVVIGSDSDGMELKELIKKKLIKEGITVVDKSETASEDFVEST
                     LAIANDLNENEGSLGIAVDGYGAGSFITATKVKGMVAAEVSDERSAYMTRKHNNSRMI
                     TLGSKIVGDELALNIVKEFLQANYDGGRHQVRVDMLNKMA"
     gene            complement(5038..5811)
                     /locus_tag="IVD26_001948"
     CDS             complement(5038..5811)
                     /locus_tag="IVD26_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP6079891.1"
                     /translation="MLKTERQRSILAMCDRYGTITVKFIQEVLNVSDMTIRRDLEELA
                     QKKKLLRVHGGAQKIDYLEMSTSIEANELSHTEKKKLHTKEKEYIAKNAAAHINQEDD
                     TIFLGSGTTIELMTRYIKPSSLRIVTNSLPVFNLLSEIKRFELYLIGGLYREKTGAFV
                     GSIANEAVQKIGIKKAFVGVNGLKGSEVSNFSIEEGTLQKIVLDNAAEKCLVSDANKF
                     DHSDFYNFYDLRKIDKLFTDSTLSAELKSYYQQFTKIIQ"
     gene            5976..6455
                     /locus_tag="IVD26_001949"
     CDS             5976..6455
                     /locus_tag="IVD26_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6079892.1"
                     /translation="MNEFFFKDTVYVSDKQSQEEVFEEVYQDLLKKELVTEDFLENLL
                     ERERNYPTGLDLSPVSKILPDIAIPHTESEFVRTTRIIPIKVKNEIPFYNMISPSDQI
                     SASFLFMILNENGEAQAGMLANIMDFINSVDEEKLFSFFKLEDTEAIYHFLEEHFYI"
     gene            6512..6814
                     /locus_tag="IVD26_001950"
     CDS             6512..6814
                     /locus_tag="IVD26_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HAP6079893.1"
                     /translation="MIKILAACGAGVNSSHQIKSALETELKNRGYQVTCDAVMIKDIN
                     EEMLSHYDIFAQIANTDLGFDINIPVVDAGAILYRIPAMAEPVYQSMESAIQSLNK"
     gene            6836..8293
                     /locus_tag="IVD26_001951"
     CDS             6836..8293
                     /locus_tag="IVD26_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol transporter subunit IIA"
                     /protein_id="HAP6079894.1"
                     /translation="MNTIIDIANKVFTPLINLGAAPLMTIVLTVIALFFKVKPSRALE
                     GGLKLGIALTGIGAIIGILTTAFSDAMTAFVERTGISLNITDVGWAPLATITWGSPYT
                     LYFLLIMVIVNIVMLAMKKTNTLDVDIFDIWHLAIVGLFAIFCGANLFIASALVIFIG
                     VLKIWNSDLMKPTFNDLLNAPDSNPMTTTHMNYMMNPIIMVFDKIFDKIFPWLDKYDF
                     DAAKLNSKIGFWGSKFAIGIYLGIFVGLLAGQTPTQIFSLAFTAAVCLELFSLIGAWF
                     IAAVEPLSQGITDFANKRLKGRTINIGLDWPFIAGRAEIWAAANVLAPIMLLEAIILP
                     GNKLLPLGGIIAMGVTPALLVVTRGKLIRMIVIGAIELPLFLWSGTLIAPFVTQTAKA
                     VGAFPAGLNGSAMISHTTMEGPIEKFLGYLVGNASQGQIEFVIYAALALGAYLLIFIW
                     YARQMKKRNAAYAAEKEENASPATAHNMTYAAEAK"
     gene            complement(8886..9638)
                     /locus_tag="IVD26_001952"
     CDS             complement(8886..9638)
                     /locus_tag="IVD26_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP6079895.1"
                     /translation="MLKTDRFQAIMSLLEVNGTVRVSDIMEKFSVSDMTVRRDLDEME
                     KQGLLERVHGGAKLKDFYRHVELSHREKQIMLQEEKQRIVEKANEMINDGDTIFLGPG
                     TTIELMSKIIQGDSLRIVTNCLPVFEELNKRKGNRKIYLLGGEMRETTQCFVGEITNK
                     SLQDMNFHKAFFSCNALNEQKIMTSTFEEGQTQQIALNNSVERFLLIDHSKIGKRDFS
                     VYYNLNDVTVVITDDDEQKHYEKIEKEEKYVV"
     gene            complement(9853..10089)
                     /locus_tag="IVD26_001953"
                     /pseudo
     CDS             complement(9853..10089)
                     /locus_tag="IVD26_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178530.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
     gene            complement(10099..11057)
                     /locus_tag="IVD26_001954"
                     /pseudo
     CDS             complement(10099..11057)
                     /locus_tag="IVD26_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(11263..12945)
                     /locus_tag="IVD26_001955"
     CDS             complement(11263..12945)
                     /locus_tag="IVD26_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6079896.1"
                     /translation="MNTIIKQIEKGKPFFEKISRNIYLGAIRDGFLTAMPAILFSSIF
                     IMIAAVPEVFNVTLPEAFSTWLWKVYGYSMGLVGLLVVATTARCLANSMNRQLSDSGK
                     QINEVSVMLASICGFVMMAADQIDGGIATDYLGTKGLLAAFVSAFVTVNVYKFCVKRD
                     LTIRMPKEVPGTITQMFRDIIPFSIAVFIAVLIDTGVRQFFGTSFAAGVIQLLQPLFS
                     AADGYVGIAIIWGAMAMFWFVGVHGPSIVEPAIAAIIYANVETNFELFKNGAQASKVL
                     TVGLGNFVGTMGGTGATLVVPFLFMLFAKSKQLKAVGKASFIPVSFAVNEPLLFATPI
                     ILNPYFLIPFLLAPIANVWIFKLFVDVLGMNSFISVLPWATPAPIGLVLGTGFSVLAI
                     VLAVVLIVVDAIIYLPFVKAYDSELVEQELKNIAAEEVKEELVEEIQEVGATAAVIVD
                     EAKASVGEGKRVLVLCAGAGTSAMLANALEEGAKETGVNLSAKAGAYGSHYDMMKNFD
                     LIVLAPQVNSYLDDLRKDADKLGIKVIATKGAEYINLTRDPKGAVDFVLKQF"
     gene            complement(12956..13279)
                     /locus_tag="IVD26_001956"
     CDS             complement(12956..13279)
                     /locus_tag="IVD26_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP6079897.1"
                     /translation="MDRKELQLLGFEIVAYAGDARSSLLTVLKEVREGNFDNVERLLA
                     DADENLTLAHNSQTKCLAEEASGNEMEVGVIFIHGQDHLMTTILLRELINDFVELYKE
                     KFAKA"
     gene            complement(13302..14708)
                     /gene="lacG"
                     /locus_tag="IVD26_001957"
     CDS             complement(13302..14708)
                     /gene="lacG"
                     /locus_tag="IVD26_001957"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAP6079898.1"
                     /translation="MNYKTLPEDFIMGGATAAYQAEGSTKEGGKGQVAWDTFLVEKGR
                     YTADPASDFYNQYPVDAELCKKFKIDSIRMSIAWSRIFPKGYGEVNQTGVEYYHKVFA
                     ELNKHGIIPFVTLHHFDTPKELFDNGDFLNRENVEHFVNYAQFCFDEFSEVHYWSTFN
                     EIYPVASNQYLIGSFPPEVQFDIEKTVTCLHNMMYAHAKTVNIFKDGGYKGEIGVVHS
                     LETKYPASDKEEDKHAAKLDDALSIKFLLDATYLGYYSDETMAHINEILAANGQSADI
                     DSNDFREMKKAANRNDFLGINNYGSHWVKEYKGESTLHYNTTGEKGSQVYCIKGIGER
                     IVREDLPKTDWDWIIYPKGLYDLLVRIQDEYPNYNKIYITENGLGYKDNFEDGIILDD
                     DRIDYLRQHFNAISDAIKMGVNVKGYFIWSLMDVFSWVNGYTKRYGLFYVDFDTQKRY
                     PKESAYWYKFVSETKTII"
     gene            15175..16182
                     /locus_tag="IVD26_001958"
     CDS             15175..16182
                     /locus_tag="IVD26_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6079899.1"
                     /translation="MVTIRDIAKKSGYSTATISRLFKGDESLSITSDTKNKIIVTAKS
                     LGYDLTKIKTTLYKIAILFWISEEQLKKDVYYQHVKDDLKNYSKKANLDLIFISKNDG
                     VKSIPDDITGFIAIGQLTKKELYYLNQKGYKGVIRGINPLPEHFDTVEPDFHEMARQA
                     INYFINEGFTKIGFIGGNFFNLETGKEEIDSREYAFRYHLEKSGLLNEKYIFSQGSFT
                     VDEGYQLTLKMKAELNEDMPEACFIPSDTIAAGVLQGCHELGINIPKDMAVISINDDD
                     IAKFVAPPLTTFKIDIEEIAKTCVDLLSDQLVYSRDISKKTLIGAKLTVRKSFIPKEE
                     V"
     gene            complement(16576..>16957)
                     /locus_tag="IVD26_001959"
     CDS             complement(16576..>16957)
                     /locus_tag="IVD26_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="2-dehydro-3-deoxyphosphogluconate aldolase"
                     /protein_id="HAP6079900.1"
                     /translation="NSLRYLEFREGAFDFQTSQQNLLTIPGAMSPTEIFKMFEMGADI
                     VKVFPANCLGPEYFNQVQAPLGSLPLMAVGGVDQTNAQNYLNNGASYVGIGSKFFEKS
                     AVHQLNYERLMELAESFIDSLRVE"
BASE COUNT         5079 a         3609 c         2787 g         5482 t
ORIGIN      
        1 tgtccctaaa gtccattgtt ttaggtaagc catcctgctt gagcccatgc actcggtact
       61 gatgagaaaa aattgatgcc tgtttctcct gaggaatgcc aattccctga tcttttactt
      121 caataatcac gctacccttt tggtttgaaa tggtgacaat taccagtttt ccttcaccat
      181 atttgattgc attgtcaact aaattcgaaa ccgcccgata aatccaacga tctcgtccat
      241 gaatcagggt tggttgatct tcagtaaacg caaacaaaag attcggataa ttcattttgt
      301 aggcatcaca aacttccgca cagatcagtg aaacgtctac gacttccgtg ctaagatcct
      361 ctgagttatt ggataatgtc aaaatatcgt caatactgtc ggtcatccga tctaaaagca
      421 ttaaatttcc ttgatcggca tgttgccgtt ctatttccag attcgtacgc aaaatagcga
      481 tggcattttt ctgctcgtgg gtcagataac tatttaatcg tcgataatcc tccaaatgac
      541 catcgaactt atcctttagc ttattaaaag ccgcatttaa tgcctcgtcc ttcacagtat
      601 ttttaggaac ttgatcaata aacgttaaat cacgcgtaat cgctaagatt tgattactgt
      661 aaattttgcg taaaaccaac caaagaataa acgttaataa catgacggca gaacaaataa
      721 ccagcaccat cgctggtaaa tatttaaata gttcgtcctg gtaagcttta tctatcatcg
      781 aaatagtcat aaattgattg ttggaagatt tcgaagcttc catctgcgtc tctgcttgaa
      841 ccgtcttacc ctcttccata aaataaacat cttcacctaa ggtagatgcg atactgattc
      901 cctccaaatt atttctcaga aagaagaaac tcactaaaat cacgcctgtc accaacagtg
      961 aaaaagccag catcgttaac gtcattttaa aatttaatag catagctggt acccctttgc
     1021 tcgaatggtt tttaagacct ctttttcagc tgcttcagcc agtttctttt ttagacgagc
     1081 cagatgcact cgcagaaccg acgaaaaagg atcaaaatct tcatcgtaga catgttcaga
     1141 aatttcctca gacgaaacaa ccgctggatg acgctgagcg atgcacagta agatatcaaa
     1201 ttccttgggt ttcaggacca cctctgtctt ttgatagctg acccttcgac ctaatggatc
     1261 aatcttcaaa gcaccaattg aaatctgcgg cagcgcacgt ccatgataac gacgaataac
     1321 cgcgcgtatt cgtgctttta attctagtaa ctcaaagggt ttgactaaat aatcatctgc
     1381 tccaaaatcc aagccttttg ctcgttcttc aatctcatca cgtgcagtaa taatgataac
     1441 tggactttcg acttcttcag cacggagact ttgtaaaaca gataatccat cttttttagg
     1501 cagatttaaa tctagtagta tcccatcgta tgaattgatg aaggccttct cttctcctga
     1561 ctcgccatca taagctacat ctacagaaat attctcctgc tctaggccct tttttacgga
     1621 taaaaccagc tcacgattgt cctcaaccac cagtacacgc atgtatattc actcctcata
     1681 cggatttagt aattacactt atgcttttta gcatagtaca cgctcttctt caaagtccac
     1741 gttctttttg tgaagatttg aagaaattca tacattctgt taaaaaacac ataattaaga
     1801 atgattttac tgtttgaaaa tacctagaat agaaaaagac tggaaccttt cctccagtct
     1861 cactactttc tatttgcttg gttttcttgt atatactttt caaagttcgt tggtttatga
     1921 ccaataagcc tcgttagaat actgaaaatt gccatcaagt cattaagtac cacatgtaag
     1981 aaaatctctc taaagaaaaa ccccttcgtt ttaactcact tactatttta gaattcgttc
     2041 ccctaataat gcagcatgat tttacgcttt atgtataaaa aaagactgca agcaattttg
     2101 cttcacagtc tgatttctta tgatagtgag cttgttaaca cttccaccgg tgtagcagtt
     2161 tctttcaata cggcatttaa ttcttcaata tttttacgcc cttgcgtatt catccactcc
     2221 atcgctgctt cttttccatc aacgatatag ctttctacac catctgccca agtcgcacgg
     2281 ccgcaaagta caccattgaa ggttgagccg gcatttttcg cgaagcgcag tgtttcttgg
     2341 aacaactctg cttttacacc ggcgcttagg aaaataaatg gcaggttagt ggcttcagcc
     2401 tgttccttga agaagttagc cgcttgtgcc tttgtgtaca cgacttcgtc tgtcccatag
     2461 ccttccacat aattcatatt gacgggtact tccaccttta acacatctac gccataacgt
     2521 ggatcagaaa attccttcat catatcgttg actttatgag gtttcttaat ggcgtattct
     2581 ttcgaagtcg catcagagat gttcgcgtca taagaaacaa gctccaagaa gaagggtaag
     2641 ttttcagcct gacattctga gccgattcgt tcaataaagg catgtttttg attattgatt
     2701 tcttctgctt catcgacatc atagtaaagt aggaacttac aagcatcggc gcctgcttct
     2761 tttaaacgtt taactgacca gatcgataat aaatctggta aacggccggg agttgacgca
     2821 tcgtaaccag ttttttcata agctaacagc aagccggcat tttttgctct aacgtcagct
     2881 gctggcaagc catattcggg atctaataaa atcgatgagg catatttcgt taattgtgaa
     2941 gaaacaattt ctttaaattc aacgatttct gattcttctg cttcgctgcc cttgaatttt
     3001 gtgatcatct tcttcaaagc cccgcgttga tcaattgcta aggccccaat cactccatct
     3061 tcattgcata gttgcttgat atattgacgt ttttcttcgt tcatttccgt atcctcctac
     3121 actttctcca ctaagatttg atcatatagt ttttgataat tggctaattg gacatagcca
     3181 gtcgtcgctt cctgagcatt cagcattcct aaaacattac cctgttttaa cacggcttca
     3241 tccgaaagac cttgttgaat cgcagcggtc aatccggcaa cggtcgcatc accagagcca
     3301 actggattga cgacatcaat ctttggaatt gtcacgcaat aaaaagtctc gtgatgtttg
     3361 gcaaaggctc cgtcgccccc cattgaaacc actatccatt caatttcatc aaacatcgaa
     3421 tctgacaagg cggcttttaa atctgataat tctgttgaga tttctcgtcc tagcagacca
     3481 gccagctctt cggtattggg ttttattagc ttaggcttta cactgcctcg caacacttcc
     3541 cttaatgctg tacctgaaca atctaaaacg acaggctttg gctgacaaac ttgcagcatt
     3601 tgtcgataaa aatcagcagg caatccttct ggcaagcttc ctgaaaaaga aatgatttcg
     3661 gctttaacag ctaatttttc gaaatgttgc aagaacgccc ttgcttcttg ttcagtaata
     3721 acaggtccgt tttctaggat ttccgtctgt tttccgtcat gtaaaacagc gatgcaatta
     3781 cgtgtctctc cgctgatagg taaaaagtca tgagcaatct cattttgagt caggtccttt
     3841 ttaatctctt cacctaaaaa accgccgatt aaaccactag caatcacctc cgtatctaat
     3901 tgcttcaaga tacgtgtcac atttaggccc ttaccgccag ctgttttgcg aacatttctt
     3961 actcgattga ctgtgtcgag cttgaaggtt tctaatggat aagaaatatc aatcgatgga
     4021 ttcatcgtta ttgttaaaat catttgtcca cccgcttaat cgtggtattc gccacgatcc
     4081 catttctcga taaattcatc gaagaaatgc ggatcagact gcttgtcact ggctttttcg
     4141 acgtgatcga ttttggcgat caattttttg ttttcttcag tttcttgata atcggcattg
     4201 atgaaggcct ctaatatgtc acagatcaaa aattctcccg taatccgagc gccaaagccg
     4261 atcacattgg catttagttg ttccttcgca tagatagcag tcgtcatatc gcgaaccagc
     4321 gcactgcgga taccaggtac tttattgaca gcgttgttaa tcccaacacc tgttccacac
     4381 aaacaaactc ctagatctgc ttctccgcta gtcacggcct ctccgacttt ttttccgtag
     4441 atcggataat gggttctggt aaagtcatag gtccccatat ccaacacttc atgtcctttt
     4501 gattttaaga aatctgatac tgccattttt gtatctgtga cgatgtggtc acagccaatt
     4561 gcgattttca tttcattcat ccttcctaat tacgccattt tatttaacat gtcgacacgt
     4621 acttgatgac gaccaccatc ataatttgct tgtagaaatt ccttaacaat attcaacgcc
     4681 aactcatcgc caacaatttt tgatccaagt gtgatcatcc gagaattatt atgtttacgg
     4741 gtcatatacg cactgcgctc atccgaaact tctgctgcta ccattccttt aacctttgtt
     4801 gccgtgataa agctgccagc gccgtagcca tcaaccgcga ttcctaaact accttcgttt
     4861 tcattcagat catttgcgat cgccaaagtt gattccacaa aatcttctga agccgtttca
     4921 ctcttatcta ctactgtaat accttctttg atcaattttt tcttgattaa ttcctttaat
     4981 tccatgccgt cactgtctga accaattact acacgcattt ttgtttcctc ctatttttta
     5041 ctgaatgatt ttagtgaatt gctgataata actcttcagc tcggctgaaa gagtagaatc
     5101 cgtaaataat ttgtcgatct tgcgcaaatc atagaaatta taaaaatcgc tatggtcgaa
     5161 tttgtttgca tctgaaacca aacatttttc tgccgcatta tctaaaacaa ttttttgcaa
     5221 ggtaccttct tcaatactga aattcgaaac ctccgaaccc ttcaatccat tcactccgac
     5281 aaaagccttc ttaataccga ttttttgaac agcttcattg gcaattgaac cgacaaaggc
     5341 tccagtcttt tcccgatata gcccaccgat caaatacagt tcaaatcttt ttatttcact
     5401 taatagattg aaaaccggca gactattggt aacgattcgg agagatgacg gcttgatgta
     5461 tcgtgtcatt aattcgatcg ttgtacccga tccaagaaaa atcgtgtcgt cttcttgatt
     5521 gatatgagct gccgcatttt tagcgatgta ttccttctct tttgtatgca gcttcttttt
     5581 ttcagtatga gaaagctcat ttgcttctat agaagtcgac atttccagat aatcgatttt
     5641 ttgtgcaccg ccatgaacgc gtaaaagctt tttcttctgc gcgagttcct ctagatctcg
     5701 gcggatcgtc atatctgaaa cattcagtac ttcctgaata aatttgactg ttatcgtccc
     5761 atagcgatca cacatcgcta agatcgaacg ctgtcgttct gttttcagca tattctgtac
     5821 ctccacgacc ttataataaa acatttacga acatttttca acacatattg ttcgtttatt
     5881 ttcgtttatg cgttgacaat gattttgtaa gcggttatac tcaacttgta aacatataaa
     5941 taaacataaa cgaactaata aaggagctgt tttgtgtgaa tgaattcttt ttcaaagaca
     6001 ctgtctatgt ttctgacaag cagtcgcagg aagaagtgtt cgaggaagtc tatcaagatc
     6061 tgttaaagaa agaattggta accgaagatt ttttggagaa ccttttagaa cgggagcgta
     6121 attatccgac gggattagat ctctcacctg tctctaaaat attgccagat atcgctatcc
     6181 ctcataccga aagtgagttt gtgcgaacca cccgtatcat tccaatcaaa gtaaaaaatg
     6241 aaatcccttt ctacaacatg atctcgccaa gcgatcagat ttccgcttca tttcttttca
     6301 tgatcttgaa cgaaaatggt gaagcacagg ctggcatgtt ggctaatatc atggatttca
     6361 ttaattctgt tgacgaagaa aaactgtttt cgtttttcaa attagaggac acagaagcga
     6421 tttatcattt tttagaagaa catttttata tatagaagtc tctgcctaac cgcaggataa
     6481 aaaataaact tattttaagg ggagaattat tatgatcaaa attttagcag catgtggagc
     6541 aggcgttaat tcaagccatc aaatcaaaag cgctttggaa actgaattga aaaatcgtgg
     6601 ctatcaagtc acctgtgacg ccgttatgat caaagatatc aatgaagaaa tgctgtctca
     6661 ttatgacatt ttcgcacaaa ttgccaacac cgacttgggt tttgacatta acatccctgt
     6721 cgttgatgca ggtgctattc tttatcgtat tcctgctatg gctgagcctg tttaccaaag
     6781 tatggaaagc gcaatccaat cattaaacaa ataggactaa agaaaggaaa agcatatgaa
     6841 tacaattatt gatattgcca ataaagtatt taccccccta attaatttag gtgcggcacc
     6901 gttaatgacc atcgtattaa ctgttattgc tttatttttt aaagtaaaac cgtcacgcgc
     6961 tcttgaaggc gggctcaaat tagggatcgc cctgactggg atcggagcta ttattggaat
     7021 tttaactact gctttttcag acgctatgac agcttttgtt gaacgcacag gtatttcatt
     7081 aaacattaca gatgtcggtt gggccccact agcaaccatc acatgggggt cgccatacac
     7141 gctttatttt ttactaatta tggtgatcgt caatattgtc atgttagcaa tgaaaaaaac
     7201 caacacatta gatgtggata ttttcgatat ttggcattta gcaattgttg gtttgttcgc
     7261 gatcttctgc ggtgctaatc tgtttattgc ttctgcatta gttattttca ttggtgtatt
     7321 aaaaatttgg aactccgact taatgaaacc aaccttcaat gacttgttaa atgcgccaga
     7381 cagcaacccg atgaccacga ctcatatgaa ctacatgatg aatccgatta ttatggtttt
     7441 cgataaaatt ttcgacaaaa tcttcccttg gttggataaa tatgatttcg atgctgccaa
     7501 attgaatagt aaaattggct tctggggatc aaaattcgcg attggaattt atttggggat
     7561 ttttgttgga ttactagcag gacaaacacc aacgcaaatt ttctcgctag cctttaccgc
     7621 tgccgtctgt ttggaattgt tctctttgat aggcgcttgg ttcatcgcag ccgtagaacc
     7681 gttatcacaa gggattaccg attttgccaa taaacgacta aaaggacgta ccatcaacat
     7741 aggtttagac tggcctttca tagcaggccg cgctgaaatc tgggctgccg ctaacgtatt
     7801 agcaccaatc atgttgctag aagccatcat cttaccagga aataaattat tgccactagg
     7861 cggaatcatc gcaatgggtg ttaccccagc actattggtc gtaactcgtg gaaaattaat
     7921 ccgtatgatc gtaatcggcg cgatcgaatt accattattc ttatggtccg gcaccttgat
     7981 cgccccgttc gttactcaaa cagctaaagc agtcggagcc tttccagccg gcttgaacgg
     8041 gtccgccatg atctctcata caacgatgga aggcccgatt gaaaaattcc taggttattt
     8101 agtcggtaat gcttctcaag gacaaatcga atttgtgata tacgctgcct tagcattagg
     8161 tgcatacctt ttaatcttca tttggtacgc tcgtcaaatg aaaaaacgca acgctgcata
     8221 cgcagctgaa aaagaagaga atgcatctcc ggcaacggcg cataatatga cttatgcagc
     8281 cgaagctaaa taagctaaaa acaccccgaa tgtctttaga cttcggggta ttattttacc
     8341 tataaaaaat aaatagatgt aaaatccatt tcaaaaagca tagcccatct cttgccacac
     8401 ccaataaaga aattatcaac gtttatgctt tttttaactc ctttaagctt gcctttgttg
     8461 gtattcctca acgattcttt ttgtgttctt gtttgttttg tgctttttga ctttttgttg
     8521 tttaattgcg aattccttga tttctttttt cctgaatcgc ttcgcatccc gcggttatgc
     8581 gtgcgatttc atcattgctt tttctgatct aactcgtttc atgtcaaaga gcttcagctg
     8641 acttagtgtc catggttgtt ttgatatccc ttttcctcct taataaagcg gtgattgata
     8701 ctgctatttt ttccttcaca taaacataac atcccaaaaa aatcgactat cttttttcaa
     8761 atggtgtatt caagtattcg gaggaattag taatgatgca ccctaaaaat aacataattc
     8821 gcttaaattc aaggctacca aaaaactacc aagttctaat tatctagagt ttggcagttt
     8881 ctcatttaca caacatattt ttcttctttt tcgatttttt catagtgctt ttgttcatca
     8941 tcatccgtta taactactgt tacatcattc agattataat atactgaaaa atctcttttc
     9001 ccaattttcg aatgatcaat caataaaaag cgttcaacag aattattcag agcgatctgt
     9061 tgagtttggc cctcttcaaa agtcgaagtc ataattttct gttcatttaa agcattacag
     9121 ctgaaaaatg ctttatgaaa attcatatcc tgtagcgatt tattcgtgat ttcaccaaca
     9181 aagcattgag tcgtttcccg catctcgcca cctaatagat agatttttcg attccctttt
     9241 cgcttattta attcttcaaa aacaggcaaa cagtttgtaa caatccgcag tgaatcccct
     9301 tgaatgattt ttgacatgag ctcgattgta gttcctggtc caagaaatat cgtatcacca
     9361 tcattgatca tttcattcgc cttttccaca atccgctgct tttcttcttg cagcataatc
     9421 tgtttttctc tatgagaaag ctccacatgc cgataaaaat ccttcaattt cgctccgcca
     9481 tggacgcgtt ctaataatcc ttgtttctcc atttcgtcca aatcacgtcg gactgtcata
     9541 tccgaaaccg aaaacttctc cataatatcg ctgactcgta ctgtaccgtt aacctctaat
     9601 aacgacatga tcgcttggaa tcgatccgtt tttaacattt catcgcctct tttcttttta
     9661 agactatcaa attcttaaga aaagtgctag aacaagtttt cttaagaagc cttctgcagg
     9721 aaggaaagca aaatttttca gaatttgcaa gctgctattc taaaaaataa aaccgaacga
     9781 gcatgactgt catagtgaca gccttgttca ttcgactttt atctttaata aatcatttta
     9841 tttaatctga agttattgtg caagttcaaa aacaaagtag ttaatgtctc ctcgatattt
     9901 cgaaatcgaa tactcaacgg gcagacgttc tagcgaaaaa ccctgtgtat ggaaatagaa
     9961 cattggatct ccttcttcca catctaacaa atcgctgatc gtatcatccg ctttgattac
    10021 ttctagtttt ctggtgaccg ttttaattgg ataacccatt tcttcaaaaa cttgatacat
    10081 tttttctttt ctgatttgtc aaattaagct agacaatatg tctttatcta tgcagctcaa
    10141 aaatacttcc aatggtgttc gataatttaa tgattttctt ggaatatggt ttcttttcga
    10201 ggcaacggat tgaataaagg tttcatccat gtccctaaag tccattgttt taggtaagcc
    10261 atctcgtcta agcaagccgt ttgagtgctc atttagccct ctttgcgaag gtgttcctgg
    10321 atctgcgaaa aagatggcaa tatcgttcga gttacttata gatcgccagt tggaaaattc
    10381 ttttccacaa tcaaatgtca tggatttaaa caagtgttta ggcatggatt tgaaccaatc
    10441 atttaacctg ttttcgatat cttcggctcg tctgcctgtc ggtttcaaag taataataac
    10501 cttggataaa cactcaacca atgtaataac agcgctcttg tgtttaactc ccacaatggt
    10561 gtcgccttcg agatgaccaa attctttagt caggtgtgga tagagactgt tccgttcatg
    10621 aatcgttctg cgaaaggcct gttttccacg cttttcttga tgattattcg gtttacgttt
    10681 ccccttcata ggtaacgact gtgtgtcaaa aaggcctttt ttaaacatcc gatagagtgt
    10741 acgaacagaa caatcaattg gaaactcgcc acggccgata atcacatcgg gtgaccaccc
    10801 ttgagctacc ttttcttgaa catatgttga ttgttcatca gataaaacgg ttgaacgtcg
    10861 tccacaacga gatttatttt gtttgtattg acggtaataa tctagcactt ttttccttgt
    10921 ttgagaaacg aataaacatt ataaatggtt tgtctagagc gatttaaact ttgtgcgaca
    10981 agagcgacag gtttctcgat attgaaataa gactctatga ttactagttc gtctgttgta
    11041 agatgggtgt aggtcatttg tactcactcc ttattaattc tttggtcgga actattttga
    11101 gtgtagcaca aatgatcttt ttagttgtct agcttaattt tacaatcgac gcctcaaaaa
    11161 gaatacccga aatttaaaca gcaaaaaaag atagcgctta ccattgtgtt taagataaaa
    11221 cgctagctaa gttggctagc gctttattaa tctaagcaag ctctaaaatt gcttcaatac
    11281 aaaatcaact gctcctttag gatcacgtgt taaattgata tattctgcac ctttagttgc
    11341 aattactttt atccctaatt tgtctgcatc tttacggaga tcatccaaat aggaattcac
    11401 ttgaggtgct agaacgatta aatcaaaatt tttcatcata tcataatgag aaccataagc
    11461 tcctgcttta gcagaaagat taacacctgt ctcttttgcg ccctcttcta atgcattagc
    11521 caacattgca ctcgttccgg caccagcaca aagtactaaa acgcgctttc cttcaccaac
    11581 cgatgctttt gcttcatcaa ctataactgc cgcagttgca ccaacttctt ggatttcttc
    11641 gaccaattct tcttttactt cttctgcagc aatgtttttt aactcttgtt ctactaattc
    11701 agaatcatag gccttaacaa aaggtaaata aataatcgca tcgacaacaa tcaatactac
    11761 cgctaataca atcgccaaca cactaaaccc ggttcctaaa accaagccaa tcggtgcggg
    11821 cgtcgcccaa ggcaatacgg atataaagct attcatcccc aagacatcga caaaaagttt
    11881 gaatatccat acgttagcga ttggtgctaa taaaaatgga attagaaagt acggattcaa
    11941 aataatagga gtagcaaata gtaacggttc atttaccgca aacgaaactg gaataaatga
    12001 agctttacca actgctttca attgttttga tttagcgaac aacatgaaca gaaaaggaac
    12061 aactagtgtc gctccagtac cacccatcgt tccaacaaag tttcctagac caactgttaa
    12121 tacttttgag gcttgtgcac cgtttttaaa taattcaaag ttagtttcta cgttcgcata
    12181 aataattgca gcaatcgctg gttcaacaat cgatggtcca tgaacaccaa caaaccagaa
    12241 cattgccatg gctccccaaa tgattgcaat accgacatat ccatcagcag cactaaataa
    12301 tggctgcaat aattgaatta cacctgctgc aaatgatgtt ccaaaaaatt gacgaactcc
    12361 cgtatcaatc aaaacggcaa taaatactgc aattgaaaag gggataatat ctctaaacat
    12421 ctgtgtgatt gttccgggaa cttcttttgg catacggatc gtcaaatctc ttttaacaca
    12481 gaatttatac acatttacag taacaaacgc agaaacgaaa gctgctaata atccctttgt
    12541 ccctaaataa tcagtagcta tcccaccatc aatttgatca gctgccatca ttacaaaacc
    12601 acaaattgac gctaacataa cagaaacttc attaatctgc ttacctgaat cagataattg
    12661 acggttcatt gaattagcta aacatcgagc tgttgtagca acaaccaaaa gaccaactaa
    12721 tcccattgaa taaccataaa ctttccaaag ccacgtcgag aatgcctctg gtaacgtcac
    12781 gttaaatact tctggaacag ccgcaatcat aataaaaata cttgaaaata gaatagctgg
    12841 catagcagtt aaaaagccat cgcgaattgc ccctaaataa atattacgtg agattttttc
    12901 aaaaaacggt tttcccttct caatttgctt aataatcgta ttcatttttc ttctcctatg
    12961 ctttagcaaa tttttctttg tacaattcaa caaaatcatt gataagttct cttaatagaa
    13021 tcgttgtcat taaatggtct tgcccatgaa taaaaattac gcctacttcc atttcgttcc
    13081 ctgacgcttc ttcagctaaa catttcgttt gtgagttatg cgctaaggtt aaattttcat
    13141 cagcatccgc taataatcgt tcaacattat caaaattacc ttctctcact tccttcaaca
    13201 ctgttaataa tgaacttctg gcatctcctg cataagcaac aatttcaaat cctaataatt
    13261 gcaattcttt cctatccatt tccttgccct cctaactatt tttatattat cgtttttgtt
    13321 tcgctaacaa atttatacca atatgcagac tctttcggat atcttttttg tgtatcgaaa
    13381 tctacataga atagtccata acgcttagtg tatccattaa cccaagagaa aacatccatt
    13441 aatgaccaaa tgaaataccc ctttacatta actcccattt tgatagcatc ggaaatcgca
    13501 ttaaaatgct ggcgtaaata atcgattcga tcatcatcta gaataatccc atcttcaaaa
    13561 ttatccttat accctagccc gttttcagta atgtatattt tattataatt tggatattcg
    13621 tcttggattc gtacaagtaa atcatataac ccttttggat aaatgatcca atcccaatcg
    13681 gttttcggaa gatcctcacg cacgattctc tcgccaatcc ctttaatgca atagacttgg
    13741 ctaccttttt ctccggtagt gttgtagtga agtgtgcttt ctcctttgta ctctttaacc
    13801 caatggctac catagttatt gataccaaga aaatcatttc gatttgctgc ttttttcatc
    13861 tctctaaaat cattagaatc aatatctgca gattgcccat ttgctgctaa aatctcatta
    13921 atatgtgcca ttgtttcatc tgagtaatac cctaaataag tagcatctaa taagaactta
    13981 attgataacg catcatctaa tttcgcagca tgcttatctt cttctttgtc acttgctgga
    14041 tattttgtct ctagcgagtg aacaacacca atttcccctt tatatccacc atctttaaaa
    14101 atgtttactg tctttgcgtg cgcatacatc atgttgtgta aacaagttac agtcttctct
    14161 atatcaaatt gaacttctgg aggaaacgat ccgatcaaat attgatttga agcaactgga
    14221 taaatctcat taaatgtact ccaataatga acctcagaaa attcatcgaa acagaactgt
    14281 gcatagttta cgaaatgttc aacattttct cgatttaaaa aatctccatt atcaaatagt
    14341 tctttagggg tatcaaaatg atgaagagtt acaaaaggaa taataccatg cttattcaat
    14401 tcagcaaata ccttatgata atattccact cctgtttggt tcacttcccc atagcctttt
    14461 ggaaaaatac ggctccatgc aatagacatc ctaatactat caattttaaa ttttttgcat
    14521 aattcagcat caactggata ttgattataa aaatcactag ctggatcagc agtatagcgt
    14581 cccttttcta caaggaaagt atcccacgct acttgccctt ttccaccttc ttttgtagag
    14641 ccttctgctt gataagctgc cgtagctcct cccataataa agtcttctgg taaagtttta
    14701 taattcattt taatctctcc ttgaaaatta gtttgatcaa tatgccaata atccataaat
    14761 cacctcagca taattttaac atgtataagt aaattttttt acacaacgaa aaaccgacct
    14821 cgaatatcta ttttattgcg atatacaagc acttatatcc cttgatgtaa aataaatata
    14881 ccattcaaaa accgttttgt aaacgttttt ttgtaaaata aatttatctt tttactaatt
    14941 taatttacac gaaacaagaa aacggactga ttcccactaa aatcaatccc acctactaat
    15001 cattctccaa gtggctatcc attatcgatt caatcttctc tgttaatgga ttaggctctc
    15061 tgctgatatc agagtttcgt ttcctgctag aaaaagtaat ttaagttact aaaagagcag
    15121 tttcgattta ctttaacaaa gaaaaggatt attatatccc taggaggatg aacaatggtt
    15181 actattagag atattgcaaa aaaatctggt tactcaacgg ctactatatc aagacttttt
    15241 aaaggtgatg agtcactctc tattacatct gatactaaaa acaaaataat cgttacagcc
    15301 aaatctttag gatatgatct gacaaaaatt aagactactc tgtacaagat tgccattctt
    15361 ttttggatct cagaggaaca gttaaaaaag gatgtctact atcaacatgt caaagatgat
    15421 ttgaaaaatt atagtaaaaa agctaatcta gatttgattt tcatctctaa aaacgatggt
    15481 gtaaaaagca ttcctgacga tattactgga tttatcgcaa taggacaatt gacaaaaaag
    15541 gaattgtact acttaaatca aaaagggtat aagggggtaa tccgaggaat aaacccatta
    15601 cctgaacact tcgatactgt agaacctgat ttccacgaaa tggccagaca agcaattaac
    15661 tactttatta atgaaggttt cacaaaaatt ggatttattg gaggaaattt ctttaaccta
    15721 gaaacgggta aagaagagat tgatagccgt gaatatgcct tccgatatca tttagaaaag
    15781 agcggactac tcaatgaaaa gtatattttc tcccaaggat catttactgt tgacgaaggg
    15841 tatcaattaa ctcttaaaat gaaagctgag ttaaatgaag atatgcccga ggcatgtttc
    15901 ataccatctg acactatagc tgccggcgtt cttcagggct gccatgaatt gggtattaac
    15961 atccctaaag atatggcagt aataagtatt aatgatgacg acatcgcaaa attcgttgca
    16021 ccaccactta caacttttaa gatagatatc gaagagatag ctaaaacctg tgtagattta
    16081 ttaagtgatc aactggtata ttcgcgggac atatcaaaga aaacattaat cggcgcaaaa
    16141 ttgaccgtta ggaaaagttt tatccctaaa gaagaggtgt aaaataagta attgaaactt
    16201 atctttaaaa ctataattgt gtccacatag tagccgagca atcgggttta tgcctattat
    16261 gttttccata aataatttga tggtgatatt ttgacgtaaa tacaatatga ttttttcatc
    16321 gccaaattgt gcgcgctaat ttttgtttat cattcagaac atttcctcct ttttatctaa
    16381 gtatgaggtt ggataaacgc ttcatcttag tatcttgggg gattttttat ctcgttggga
    16441 atatatcaag catcagagcg cgcaaaaaga actggtcgaa aaatcaatct accagttcaa
    16501 tctcattcac tgtgatacta tgttttatac agataacgcc atattataaa acaagttgta
    16561 ttccgcaaat gggttctatt caactcttaa actatctata aaagattcag ccaactccat
    16621 tagcctctcg taatttagtt ggtgaacagc acttttttca aaaaattttg aaccaattcc
    16681 tacataagag gctccattgt tcaaatagtt ttgtgcatta gtctgatcta cccctcctac
    16741 agccatcaaa ggtaaacttc ctaaaggggc ttgcacttga ttgaaatatt ccggtccaag
    16801 acagttggcg gggaacacct taacaatatc agcacccatc tcaaacattt tgaatatctc
    16861 tgtgggcgac atggccccag gaattgttag aaggttctgt tgcgaagttt gaaaatcaaa
    16921 cgcgccctct ctgaactcca aatatcttag gctgtta
//
LOCUS       DACBYO010000061        16813 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.061, whole genome shotgun sequence.
ACCESSION   DACBYO010000061 DACBYO010000000
VERSION     DACBYO010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.061"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..285
                     /locus_tag="IVD26_001960"
     CDS             <1..285
                     /locus_tag="IVD26_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079901.1"
                     /translation="LTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKN
                     NQISLDITNQAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            288..1709
                     /locus_tag="IVD26_001961"
     CDS             288..1709
                     /locus_tag="IVD26_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP6079902.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            1706..3583
                     /locus_tag="IVD26_001962"
     CDS             1706..3583
                     /locus_tag="IVD26_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP6079903.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            3675..4517
                     /locus_tag="IVD26_001963"
     CDS             3675..4517
                     /locus_tag="IVD26_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP6079904.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(4669..5544)
                     /locus_tag="IVD26_001964"
     CDS             complement(4669..5544)
                     /locus_tag="IVD26_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP6079905.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            5751..6782
                     /locus_tag="IVD26_001965"
     CDS             5751..6782
                     /locus_tag="IVD26_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAP6079906.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            6871..7176
                     /locus_tag="IVD26_001966"
     CDS             6871..7176
                     /locus_tag="IVD26_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAP6079907.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            7355..9370
                     /locus_tag="IVD26_001967"
     CDS             7355..9370
                     /locus_tag="IVD26_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP6079908.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            9372..9656
                     /locus_tag="IVD26_001968"
     CDS             9372..9656
                     /locus_tag="IVD26_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6079909.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            9682..11055
                     /locus_tag="IVD26_001969"
     CDS             9682..11055
                     /locus_tag="IVD26_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAP6079910.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(11138..13153)
                     /locus_tag="IVD26_001970"
     CDS             complement(11138..13153)
                     /locus_tag="IVD26_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAP6079911.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(13175..14389)
                     /locus_tag="IVD26_001971"
     CDS             complement(13175..14389)
                     /locus_tag="IVD26_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6079912.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14610..15554
                     /locus_tag="IVD26_001972"
     CDS             14610..15554
                     /locus_tag="IVD26_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6079913.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            15850..16794
                     /locus_tag="IVD26_001973"
     CDS             15850..16794
                     /locus_tag="IVD26_001973"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAP6079914.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
BASE COUNT         5614 a         3076 c         3205 g         4918 t
ORIGIN      
        1 ctgaccgaaa cttttacacc agaaggatac caaggtctaa aagagccagt tactatagtt
       61 atacacgaag atgggtcaat tcaagtggat ggacaagatc atgaatctgt tctgtcacca
      121 ggagccaaaa acaaccagat ttctttagac atcacgaatc aggcaaaagt accattacct
      181 gaaacgggag gaattggccg tttaggaatc tatctagtag ggatgattgg ttgtgcgttt
      241 tctatttggt atcttttttt gaaaaaagaa agagggggca gctaaatatg aaaaaacttg
      301 gttggcttag tatgtgtctc ttcttgttac tatttaaacc agcttttact caggtagcaa
      361 cagaaacaga aacagaaatg gttcagatta ctttacacaa attgcttttc ccaaacgggc
      421 aactgccgaa aaatcatcca aatgacggac aagaaaaagc tttattacaa acgtatcgag
      481 gattaaatgg tgtcacattc caagtttatg atgtcacaga ttctttttac catctacggg
      541 aaaagggcaa aacggtagaa gaagcacaag cagagatcgc aaaaaacggt gcgtcttccg
      601 gtatgtttac cgcagaagca acaactacaa ctcttaacaa cgaagatggt atcgcttctt
      661 tttctctggc cgctaaagat caagaaaaaa gagataaagc gtatcttttc attgaatcca
      721 aagtaccaga agtcgtcaaa gaaaaggcag agaatatggt agttgttctt cctgtacatg
      781 gacaaaacaa tcaaaaactt tcaactatcc atttgtatcc taaaaatgaa gaaaacgact
      841 accctgatcc accttttgag aaggtattag aagagcctag aaatgatttt acgattggtg
      901 aaaaaatcac ttattccttg catacgacaa ttcctgtaaa tatccttgac tatcaaaagt
      961 tcgaattgtc agatagtgcg gatgaagcat taacgttttt acctaatagt ttaacgattt
     1021 catcgaatgg agaaaagctg acagaaggct ttgtcataca caagaaacct cacggatttg
     1081 atgttttatt ttcgatccct tcgttggaaa aatatgctgg aaaaaaactg accatttctt
     1141 atcagatgca gctaagcagt acagcacagg cgaacaagga aatcaacaac aacggaacac
     1201 tggattttgg ttttggtgtc agtacaaaga aagtctctgt atatacaggg agtaagcaat
     1261 ttgtcaaaat cgagacaaat aaaccagata aacgattagc tggcgcagta ttccttatta
     1321 aaaacaaagc aggaaattac ctccagcaaa cagccaacgg atacaagtgg acaaagaacg
     1381 aatcagatgc gcttcacctg atttccgata aaaatggcgc tttttcaatt tccgggttga
     1441 aaacaggaag ttatcgatta aaagagatcg aagcaccttc tggttatatt ttaagtgaaa
     1501 cagaaattcc gtttaccatt tcaacttttc tttctgagga taaagaggcg gacagtatat
     1561 tgaaagtagt caataaaaaa gaaaatagcc gtccatttct tccaaaaaca aacgaaacga
     1621 aaaatacact tttaggcgtt gttggtatgg tattcgcaag ctttgcaatc tggttgttta
     1681 tcaaaaaaag aacaggagtg aaaaaatgaa aaatcataaa aaaataaacg ttatgttagg
     1741 agtccttttc cttattttac cattactcac aaacagcttc ggcgcaaaaa aagtgtttgc
     1801 agaggagaca gcagctcaag tcatccttca taaaaagaaa atgactgatt tacccgatcc
     1861 tttaatccaa aacagcggga aagaaatgag cgaattcgat caataccaag gattagccga
     1921 tatttcattt tcagtttata acgtcactca agaattttat gcgcaacgag ataaaggagc
     1981 gtccgtggat gcagcaaaac aagcagtcca gtctttgact cctggtacac cagttgcttc
     2041 aggaacgaca gatgctgatg gaaatgtcac tttatcttta cctaaaaaac aaaatgggaa
     2101 agatgcagtc tacacgatca aagaagaacc aaaagacgga gtgtcagctg ccgcaaacat
     2161 ggttttagct ttccctgtat atgagatgat caaacaagca gatggctctt ataaatacgg
     2221 gacagaagaa ctagatacta tccatctcta ccctaaaaat acagtcggta atgatggaac
     2281 gttgaaagtt acaaaaatcg gtactgccga aaacgaagca ctaaatggag cagaatttat
     2341 tatttctaaa gaagaaggaa caccaagcgt caaaaaatac atccaaagtg tcacagatgg
     2401 attgtacact tggacaactg atcaaaccaa agccaaacat ttcattactg gtcattctta
     2461 tgacatcggc aacaatgact ttgccgaggc atctattgaa aaaggccagt tgatcgttaa
     2521 tcatttagaa gttggaaaat ataatttaga agaagtaaaa gctcctgata atgcggaaat
     2581 gattgaaaag caaacaatca cgccttttga gatcctggca aatagccaaa caccagtaga
     2641 aaagaccatc aaaaatgata cgtctaaagt tgataaaaca acacctcaat tgaatggaaa
     2701 agatgtcgca atcggtgaaa aaattcaata tgagatttct gtcaatatcc cattaggtat
     2761 cgctgataaa gaaggaacgc aaaacaagta cacaacattc aaacttatcg atactcatga
     2821 cgctgcttta acatttgata atgattcttc aggaacgtat gcttatgcct tatatgatgg
     2881 aaataaagaa atcgacccag taaattattc tgtcactgag caaacagacg gattcacggt
     2941 ttcagttgat ccgaattata ttccttcatt aactcctggc ggtacattga aattcgttta
     3001 ctatatgcat ttgaacgaaa aagcagatcc aaccaaagga ttttctaacc aagcaaatgt
     3061 cgataacggg catacaaatg atcaaacacc accgtcagtc gatgtcgtta ctgggggcaa
     3121 acgatttgtt aaagtagatg gtgacgttac atcagaccaa acacttgctg gagcagaatt
     3181 cgtcgttcgt gatcaagata gtgacacagc gaaatattta tcgatcgacc catccacaaa
     3241 agccgtcagc tgggtatcgg cgaaagaatc agcaacggtt tttacaacca caagtaacgg
     3301 tttaatcgat gtgacaggtc taaaatatgg cacgtactat ctggaagaaa cgaaagcgcc
     3361 agaaaaatat gttccattaa caaaccgtgt agcatttact atcgatgaac aatcttatgt
     3421 aacagcagga cagttgattt ctcctgaaaa aataccaaat aaacacaaag gtacacttcc
     3481 ttcaacaggc ggtaagggaa tctatgtgta tatcggtgca ggagtagtcc ttctactgat
     3541 tgctggactg tactttgcta gacgcaagca cagtcagatt tagtcttttt gcaagaattg
     3601 gaaaaaggag cagcggatta cgcaaatgct cctttttctt ttattatcaa acagtcatca
     3661 caaggagaac acaaatgaaa ccaaagaaaa ggaaacttct agatctgctg atgcttttct
     3721 tgcttctctc aggaataggg atactagctt atccatttgt tagcgacgcg ctgaataatt
     3781 atctggatca gcagatcatc tctcattatc agcaacaagc ggtcaaagaa aatgaagaag
     3841 tcatggctaa aatccaagaa aacatgacaa agaaaaacca gcaattagca aaagaaggtg
     3901 gaaatccagg tgcagatccc tttactaaga aaaaagaacc tgcgaaaaag gatagaacct
     3961 attttgagaa acatacgatc ggtattttga cgatccctga gatcaatgtc catttgccaa
     4021 tttttgatga aacgaatact gtgctgctag aaaaaggtgc ctcattattg gaaggaacgt
     4081 cttatcctac ggggggagaa aatacacatg ccgttatttc cagccatcga ggactgcctc
     4141 aagcaaagtt gttcacagac ttaccgaaac tgactttagg tgattctttc tatatcgaaa
     4201 tcaatggacg gacactcgct tatcaagtcg atcagatcaa gacggtagaa ccgactgata
     4261 caaaagatct gagaatcgaa aaagggcagg atttcgtgac actcctaact tgtacacctt
     4321 atatggtcaa cagtcatcgc ttacttgtca gagggcaccg ggttccttat catgcaaaag
     4381 aagttcaaaa agaagtacag aaagtatccg agaacaaacg atttttcctg tatggattgt
     4441 tagctgcatg tatactgatt ttcctccttc ttatatatct ttttcgtcaa tcgttcaaaa
     4501 taagaaacag aagttagcta ttcctcattt ctataatata tctattcgaa tcgttccgta
     4561 aacaaacagg ctgaggtttg aaaaagaaaa cttcagcctg tttttatgat gatatcaaag
     4621 agagcctatc aaacactatc tttcttatta ctaaatgagg atcttttctt aagttttccg
     4681 atattcttta agaaggcctt tttgcatcaa ttcttgtttg tttttcaagt tgcggatatt
     4741 ctcttcaaaa ttttgagaat atatcactga gaataacgta tttaatacgt aatcgaaggc
     4801 aatttgagag gagaaagtcg ctactttagc aaaatcatat tcctcctgcg atataacaag
     4861 acacatatca gcctgtttgg ccatttctga atgctgattt ccggtaatca gcaaggtagg
     4921 ggcctctaca tgcttcaaat aggtcattat tcgttcataa tgatggatgc gaccgctgta
     4981 gctaataaaa atggcgcaat cctcgctagt caaattggct gcattccaag aagaatcact
     5041 gtattcttca gccatgatca aaaacttatt caacttgacc attttattct ggaatttcct
     5101 tgccgtgatt tgagaatcac cttttgcaaa aagaaagatt cgctgtgcct tgttcaatac
     5161 tttaccgatt tgatctaaat cttcatgttc aatctgcaat tgtgcttttt ttattgactg
     5221 gatcgataaa tccgccattt tctttgcaat ttgctgagtg ctatcttcac ttgaaaaagg
     5281 aaaattagga tcaatcgttt gattgaactg agcaatcaat tgatgaactt cccgccccag
     5341 ctcgaaacgg aattctttaa atccgctgaa tcccattttt ttgcataaac gaatgatagc
     5401 tgaatgggaa gtatacgtag cttttgctaa ttcttcaatc gtcatgtaga ctgcagcttc
     5461 gatattccta cggatgtaat cgacaatccg tttctctgtc gtggtaaaca actcttgttt
     5521 tgttagtttt tcttcaataa gcatgatctg acctccaaat tctatcttac tgataaacac
     5581 ttggttccgc tactatcttt ttgattttta tccttacttt gaacattaat ttcaccaaac
     5641 cgaatgataa caagtgtttt tctgaacttt tttaccagaa tagctattat aaatactttc
     5701 tgcgcttttc taggatatac tgaaaacatc aataaaagga ggcaccactc atgcttacaa
     5761 tcgcttatct tggcaatgga aagagtacaa atcgctatca tttgcctttt tcaagaaaac
     5821 ttacgaacaa aatcaatatc aaaaaaattt tttccccatc tgaaccagtg tggaaaacat
     5881 tcgaagacat cgaatatact gatcagctgt ctgatctttg ggatgatcct gagatccaat
     5941 tagttgtcat cactacacct agtcaatttc attatgaata tggaaaaatg gcactcgaac
     6001 atggtaagaa tgtactagta gagaaacctt ttgcagaaac gtcaaaggaa gcagaagagt
     6061 tatttgcatt agcaaaagaa aaaggtctat ttatccaatg ttaccaaaac agacggttcg
     6121 attctgactt cttgacagtc caaaaagtaa tcgaaagcgg aaaattaggg gatattttag
     6181 aagtagaaat gcattatgat tatttcagac cggaagtacc agaaaatacg catgaatttt
     6241 ctactgcgaa cagctattta tatggacatg cttgtcatac agtagatcaa gttctttctt
     6301 atttcggcga accagatgat atcagctatg atgtacgtca acttttaggg aaaggacgaa
     6361 tgaatgatta cttcgatctg gattttttct atggaaatat gaaaatttcg ataaaatcca
     6421 gttatttccg catcaaagaa cgtccaagtt tcgtcgttta cggaaaaaaa gggatgttcg
     6481 tgaaacaaac aaaagatcga caagaagaac atctgaaaat gttttacatg cctgatcatg
     6541 aagactttgg tatcgatttg cccgaacatt atggtgtatt gacctatata gatgaacaag
     6601 ggagttatca tgaagaaaaa gtaatttccg aggttggtga ttacagccgt gtctacgaag
     6661 ggatttacga gacattagtt aatggcgcag aaaaagtcat caaagatgaa gaaacaatct
     6721 tacaaatgaa aattttggaa gaaggaatca aaagcattca agaatcagaa ggaaaaatat
     6781 gacatatttg taagaatcgg gtttgttttt tgacgcataa actgtcttat tgtacgatga
     6841 aaaagtatag aactactagg aggaaccaac atgacaaatt atgacggtga aaaacacaaa
     6901 cgattaagag gttcaatggc ccctaaaaca gaagaagaag tggctttagc aggaactaat
     6961 tctggtgaaa cagaagacaa agaagaatca ttagctggca caaactctgg tgaaacagaa
     7021 aataaagaaa cagctttatc tggttcaaat tctgtagaag aggaaacaaa gcctaatgag
     7081 cccaatcact ttgaaaaaga tatcgaaaaa gcggttgaag atgtcaaaga aaaatttgaa
     7141 gaactgacct caaaaaataa acatgatcat cattgatcgg acgaaatcaa ttcataaaag
     7201 caggagacat ttggtcacct gctttttttc tgtatccatt cgatagaaat cgttcggtac
     7261 agtcgtaaaa aaaatccaac tgtaagttgt accaaacacc cctcgattta aaagcgctac
     7321 catactagaa tataagtagg aggtgaacag cgctgtgaac tacaaaatta gttatctcct
     7381 gaaaacacca agagaaatca gtctagaaaa agcagcagag atcatcgaag taaatacaag
     7441 cgaggcgatc aaacaattaa ctccttttgc cgaatatgtg gatgataccc gtatccgtat
     7501 aaagaaattc cgagcaatcg actgggcaga aaaatttttg gatattactc gatttgaagc
     7561 tgtgtatacc gaacaagagc gaagagatct tctttatttg atggtttatt cgactgcaac
     7621 gtctgtttct gtttttcatt ttcaagattt tcttcaggtt tctaaaggga cagtcctgtc
     7681 agatatcaaa aagataagaa atgaattaga agtggaagat tgtcagctgt cgtatactag
     7741 gaaaactggt tttaggctgc tagggtcaga agcaatatta agaagagaag caaaaaatcg
     7801 cactgctcgt ttgatgcagt cacttgctgg aagatttggg ctcacgtatt taaccgcaac
     7861 cctttccatt gattattacg ccaaagttag agatttgcta gataaaacga tttcactatc
     7921 agatcttcga ttcgcaccaa atcgaatgga tgaattagct tattatttga gtttgacaac
     7981 cattcgaatt ggaaaaacat ccatggaact ggtaaaagat gctgaactgt tggcttctct
     8041 tgcagtcact gacattagtc gacaagtatt gactggcctt ggctattccg aacatcaaaa
     8101 ttcggagatt atatttttct ctctttgctt agcatcgatc gttgaaggag atgtccagga
     8161 gcctgcactt gattttttgc tggaatgttc ttcagaagtc atccatcgca tggaattcct
     8221 gatggccgta gaatttgctt cgtttcgtga attattgatg aatgtctttt atcacttggt
     8281 ccctgcctat tttcgtattt cctattcttt ttatttacct aatgtgatga tcgatcaaat
     8341 taagcatcaa tatgcttcca tctacgaaat gacaagaaaa gcattacttc cgttagaaag
     8401 acgaataggg aagagcatcc ctgaagaaga gattggtttt ttcactatac tatttggcgg
     8461 agagatcaga aaagcggacg cagaagaaag aaatagaaaa ataagagccg tgatcgtctg
     8521 tccaagtggc attagctctt cattgatctt aaaaagtgaa cttcagcaat tattcccgat
     8581 gatctttttt acagagacta attcagctga ccgcttacac gaggttgacg aaacttctta
     8641 cgatattatt ttttctactg tacctctcac acttactgat aagaaaaagt ctctctatgt
     8701 tctgcatcca atcatgactg acttggaaaa aaatcagctg atcaatcaag tacaaagaga
     8761 ttggctgata ccaggatttt caatgccttc tgcccaagaa ttgttgtcgg cgctactgcc
     8821 ttatatcgaa ttaaaagaag gcgtagacga agaaaagctc tatcaagtat taaatcgtaa
     8881 aatgaacaaa cttttagaaa agaaggagga tcaacgtcct atgctatctg aattattaac
     8941 agaagaaatg atccaattat cggatcaacc aaaaaactgg caagaagcaa tcacatttgc
     9001 cgcacagccg ctattatcag aaaataaaat agaagaaagt tatatcaaag ctatgatcga
     9061 gcgcgtggag cagtatggtg cgtttatcca tattggcgat cacatcgcat tacctcatgc
     9121 tcgtccagaa gatggcgtaa acgaagtagg gatgtctttg ctgaaacttc aacaacctgt
     9181 ggatctgctt gataatccag cccatcccat tagtttgttc atctgtttag ctgctatcga
     9241 taatgaggca catcttcggg ctttggcaaa tttaacaaag ctactttcta ataaacaaaa
     9301 tcttcaagat ttattacacg catcaacaaa agaagaaata ttagcgatca taagaaaagg
     9361 agacgaatga tatgaaaatt tttgcagtat gtcaaagtgg attaggaaca agttttatgg
     9421 tagagatgaa catcaaacaa gcacttgcag atcttggagc agatgtggac gagtttgaag
     9481 taagtcatac ggatgttgga agtgtatcta gcgatatggc tgattatttc ttcattgagc
     9541 attctttgaa agatacgcta acttctatac ctgatgaaaa gctcgtacct ttgcaatcga
     9601 tcattgacag cgaagaagta aaagaaaaag taacgaagat cttgtcaaaa gaataaaaat
     9661 gattcaaggg aggaactatc aatggataaa ttgttgaatt tgtttgtgtc aatcgtcagt
     9721 cagccctcca tcctcgtttc tttgattgca ctgcttggtc tcgttcttca gaagaagaaa
     9781 ttttcagaag tgatccaagg aactatcaaa acatttgtcg gattcctagt actgatcggc
     9841 ggtgctggtt taatcagtaa ttcactaacc ccttttgctt cgatgttcca aacagctctg
     9901 catactcaag gagtagttcc tagcaatgaa gcagtagtgg cgattgcttt gcaacaatac
     9961 ggtacaccta ctgctttgat catgctagta gggatgatcg tgaatatttt acttgctaga
    10021 ttcacaagat ataaattcat ttttcttaca ggtcaagcaa tgctttatgt ttcttgtcta
    10081 acagcagtca ttttagtaag cgcggggttt actgcaaatt tgtggatgat cttattaggc
    10141 ggggtcttcg aaggaacact attaactatt acgcctgctc tttgtcaacc gtttatgaag
    10201 aacatcactg gaaacaatca agttgcgtta gggcataccg gaaatatcgg ttatgcttct
    10261 agtggatgga tcggaaagtt ttttggaaac aaagaccgtt ctacagagga cataaagatt
    10321 cctaaaagtt tcagcttttt gcgagattct actgtatcga tcatgctctt gatgtcgatc
    10381 gtatatgtcg cacttgcttt gttagctggt cctggatttg ttgaaagaga actaagcaat
    10441 ggagacaacg ctgtaatctt tgcactgatc caagctggaa cattcacagc tgggtttgtt
    10501 atcgtccttc aaggggttcg aatggtgttg gcagaaatcg ttccagcatt ccaagggatt
    10561 gctaaaaaac tcgtacccga ttctaaacca gcattagatg ttcctatcgt ttttccatat
    10621 gcacctaatg ctgtattaat tggctttttt gttagcttct ttgtaggaac actatccatg
    10681 tttgctatga taggcttgca aactacagtt atcattcctg gggtagtagg acatttcttc
    10741 tgcggagctg cttctggtgt cttcggcaac tcgactggcg gtagaagagg ggcggtatta
    10801 ggttctgctt tcaatagctt attgattagt tggctgccat tatttatcct tccagtatta
    10861 ggagatctta aaatcgcttc ttctacattt gccgatactg attatctagt accaggactt
    10921 gtacttggga aactaggaga atacggtcaa atagccttga cagttggaat catcgctttc
    10981 tttttacttg tcgtattatc tagctttctt tttgccggaa aaagaacaaa cattgtttct
    11041 aaagaacaga attaagcaaa cttcaaaata aaaattgctt ggacaatatc agaagaagat
    11101 ttaaagtctt ctgatatgtc gcaagcagtt ttttgtttta tgcatttatt tttgaatagc
    11161 ttgttaagac aagtggctgt tttgctagaa gaggataact tttaccattc attttcactg
    11221 ttccgcctgt tctatcagaa gtaatcacga tcttatcttt tgttttttca agcgaaatct
    11281 ttccatcttt gataggtagc gtacaattca gtgtttcaaa tgaatctaga ttaggttgta
    11341 tcataaattc ttcataacct ggctttgttg gatacaaacc gataaaatag cgtcctaaaa
    11401 gatagattgg gcttgctccc catgcatggc ataagctttt tccataagga tctccataca
    11461 tactgtactt ttcatttcct gtttgagtag ggtcgtattc ttcccagaaa gttaccgcat
    11521 catgagataa catccctccc caataatcaa gaatcgtttg gtagacgata ttcgtctgtc
    11581 cgagtttgca taaagcatct tgttcataga atttgaaata tggagtagta atctgtgtga
    11641 tagtgtcatt caataagaca ttctttaaga tcgattgctg ttggtctttg ttagcaaaat
    11701 cgaataaaac agcgaaaata ttcgcatgac gcgtcacatt tcttctccca gattcatagc
    11761 aatcgataaa agcgccaagt tcttcatccc aaaagtagtc aaataggttt tgtttcaata
    11821 gttgatattt ttcttgatag agatgagtat gataattttc gttctctcca tatgtttcag
    11881 ctaagatatc tccgcaagtg atcatggaat gataggcttt cagtaataag acttgttctg
    11941 cagcaagcgt tccttcttta tccatttcag accaatcaat aaatatccaa tcttttgctc
    12001 tcccataaat aaaccctaat tcattcgttt gctccatcaa gtatctcatt aatgattgca
    12061 tcttagggta gacgatgcgt aaaaattcat agtctttcgt catcatatag tggttttcga
    12121 taccaatcaa ccacaagatc gaatagtcaa cgatagtatt catatgctgc ttgatttcat
    12181 tttgtcctct taatgctaat atcgttcgtt tattgatttc ctcgtcaaaa aaaagatatt
    12241 gattgatcat gaatgattga tacgcatctc cagaccaaat ccagcgatct cgtttgatac
    12301 cgtcgataaa aaacaaatca ctacataact tgaaggcttc ttctgatact gaccagatct
    12361 gattcagtaa agaagaatcg cttgaaaaag cagcttgttt cgaaagagat aaaaattcat
    12421 gaaaaacttg aagttgaacc attccagtag aaacctctgg tataaacaaa tagcgaaaag
    12481 cgcgtttacg agctttcatt tttcttgtca ttcctatttg cttatagtag caataatcga
    12541 tatccatagc ttctacatcg gactctccat aacatagagt gatagattcg atatggtcat
    12601 ccagagatat tagttctaca cagccattca ctgctcgccc aaaatcgaat aagattcctc
    12661 cgccaatctc cgtttcagtg actggatgga cgcattcttt ttgataatag atttgatttg
    12721 gatcttttgc gatatcgaca taaagcggac tccagccagc tggatattct tcaataaaat
    12781 tacttgctgt ccagccaata tctgatttta cttcgtctcc ctcgataaac atcgctggta
    12841 gccctgatgt atgtcctaca aagatacgaa tttttgcttt accagctgga caagtcagcc
    12901 attttccaca tggatgtttt tgtccattaa tttctacata cccaactcct tggatcgtca
    12961 ctttaaacat ggaaggttga tcaagaaagt aatatctctt aaacttgacg ttccgatggc
    13021 aatcatccat gtaccagtac gctggccagt caaaacctcg ttcttcccgt tggaaatttt
    13081 gtagcagtcc atggcggatc tcaaagtctc caggatacca aagccatcta tctttatgtt
    13141 tttcatttgt cattttacac gacctccatc aaatttattt tgttgtcaat tgttctttta
    13201 tttcttcatc tactcttatc actgtctttc tattcgtcct gtgtactact agaaggctaa
    13261 taagcgcgct aatcaacagc aagatactgc cattgacgaa aacagcaagt gttttactcc
    13321 caagagaagc aaaagagaga aagagcaaac catatggtgc aatgaaagta cctaaattag
    13381 cgccaaccaa taagattgaa gtattgaaac tctccgcgta cttgggcgct tggatactta
    13441 cttggttgaa taagtaagga atgaataacg aaaaagaaat tcctgttagg atcgcaccaa
    13501 acccaatcac atacaggttt atcacagtgg caatcaatac aaagccgatt cccatcagta
    13561 gtaaagaaag tgtaagcata tagcgatgtg cttttgtctg aagccagcca aaacaaactc
    13621 cggcagccat acttgccaat tgcatgattg ttaagatatt cgctgcatta gtttcgtttc
    13681 ctagagaata agtcgtcagg actgtggcta atttaatcga tacagcatta tataccacga
    13741 tgaccagcaa gagaaaaata ccataactaa tcattttagg attcgttttg attacttgtc
    13801 ttgttggggc tgtgccatgc gattgaagtt cagttgtttc aggtgtagga acaaacaaaa
    13861 caaacaagac aagaataggt aagctgatgg cgtagactaa aaaggtatat tgccaaccga
    13921 actgtactag ctgtcctgca acaaatgtca ttaaagctgc accaaatcct tgaaatgcac
    13981 tttgaaaacc aatcatagag gctcgttcat ctccgtgata aaaggcagca atcatgctga
    14041 ctgccaaaga attgatcaat ccaaagccaa tacctagtcc agctcttgaa gctaagacaa
    14101 tactgtaact ttgtgagaag agggggagga taccacaaat cgatgcaatc actaatccga
    14161 tgatcacagt ttgtttttgt ccgattttcc tagcaataaa actactaatc aaaacaaaaa
    14221 tagtgaccat aaaagaggga gcagtcgtta ataattcaac agcagataaa gaacgcgtgg
    14281 cataagtagc tgacatactg ggaattgcag acgtgactgc accagcagaa gtcaaaataa
    14341 gagagactga cagcagagaa aatttcatca tctttttatt cataagcatg ttcctttcat
    14401 ttttgtaagc gcttatcaaa aatatagtat gaagtggtta ttctctcaat agcggaatca
    14461 caggaagttc atgtcccaac catagaaagt ctttatgaaa ccaaaaatag ctttgcatat
    14521 aatagcagta cagcgtgaac taataagcga aagaaaccgc ttacaaaaag gagggagtca
    14581 attggaacta gctgaattag acattttttt tgcgtaacga agaatcaatc gaaactctgc
    14641 agcgtgaaca aggaatgaat atcaatgatt taaacttagc ttaccatctt cagacaccgc
    14701 caaaaatcca ccgaggggat ctatttcaac agggaaatat tcatatcagt aaacaccgtc
    14761 gatatgcgga agttcccgag catacacatg attttgttga aatcaattat atgtatagcg
    14821 gtacatgttt acaaattatt aatggagaaa ggatagagat ggaagaaagt gacgtggtga
    14881 tcattgataa agaagctact caaagaatcg aatacacagg gcaagaggat attttaatca
    14941 acatcttatt aaaagaagaa accttatcta cagagatatt gaatcatttg gcaagcacaa
    15001 ataatctact ttcttctttt ttgataaatg catcaaaaga aaaaggggaa catacacaat
    15061 tcattcattt tcgcggcgga aaaacaagtc gtttgacgca tttgattgaa aatatgctgt
    15121 tgatttattt tgatacatac agtcataaga tccgttcgtt aaatctctat acatcactat
    15181 tactgatcga attgactcat ttattagaac aacaaagctt ttcatcagca gatggatgcg
    15241 cagaaaatga gatgcttaga gtattagatt atatcgataa gcattttact tcttgtacgt
    15301 taaaagaaac agcagctcat tttggctaca atccggtcta tcttagtaat aaattgaaaa
    15361 tgtattttga tgcttccttt caagaactgg ttctaaagaa aaaattcgac tttgcgttgg
    15421 aactgattca agaaacgagt ttttcgttgg aagaaatcgc taatcgtatc ggatataaac
    15481 aaacgacttc tttattcaaa ttattcaaga agtattcaac atgtactccc aatgaatgga
    15541 gaaataaaca ttaagaagaa aatctttcac taaagcatat gaaggaaaat tgttttaggt
    15601 gcgattgctg tcttattata tcgttgcagc gaattttttt ggatttattt tcagttctaa
    15661 acttttggtt gtattatcag gggatatagg tgtaaacatt tgtcatttat ctgttatgcg
    15721 tattcaggaa ttcgtttcca tcaaaaatta taataacaac tattataatt aacatgttga
    15781 taaaatgaat aaacaagact atacttttca tgaaagtaac aaatagttat gaaaaggagc
    15841 tgtttattca tgaaaaaaac aagtcgtaaa gtagtaatcg tcggtacagg ttttgttgga
    15901 acaagtatcg cttatgcaat gatcaaccaa ggaatctcta atgaattagt attgatcgat
    15961 gtgaatcaag aaaaagcaga aggggaagca ttggaccttt tagatggtat ggcttggggc
    16021 gatgaaaatg tggctgtatg gtcaggtggc tatgaagaat gtaaagatgc tgatatcgtt
    16081 gttatcacag ctggtatcaa ccaaaaacct ggtcaatctc gtttagattt agttaaaaca
    16141 aatgcgtcaa tcatgcgcca aatcgtaaaa gaaatcatgg gatcaggatt cgacggtatt
    16201 atcgttgttg cttcaaaccc agtagatatt ttgacatata tcgcttggaa cgaatctggt
    16261 ctgccaacat cacgtgttat cggtactgga acaacattgg atacaactcg tttccgtaaa
    16321 gaaatcgcat tgaaattaaa agttgaccca cgcagcgtcc acggctatat cttaggtgaa
    16381 catggtgatt cagaagttgc tgcatggtca catacaactg tcggtggtaa accagtgttt
    16441 gaaattgtag aaaaagacca tcgtattgcc caagatgaat tagatgtgat tgctgataaa
    16501 gtccgtaatg ctgcttatga gatcattgat cgtaaaaaag caacttacta tggtattggt
    16561 atgagtactg cacgtatcgt aaaagctatc ttgaataacg aacaagctgt attgcctgta
    16621 tctgcttatt taactggtga atacgacgaa aaagatatct ttacaggtgt gccatcaatc
    16681 gttgacgaaa atggtgttcg tgaagttgtt gaattatcaa tcaacgaaga agaaaaagca
    16741 atgttcagca aatcaacaag tgctttaaga gaagtattga acactgtatt ataagaaaca
    16801 atgaatatga act
//
LOCUS       DACBYO010000062        16753 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.062, whole genome shotgun sequence.
ACCESSION   DACBYO010000062 DACBYO010000000
VERSION     DACBYO010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16753
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.062"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(451..1761)
                     /locus_tag="IVD26_001974"
     CDS             complement(451..1761)
                     /locus_tag="IVD26_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAP6079915.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="IVD26_001975"
     CDS             complement(1773..3191)
                     /locus_tag="IVD26_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6079916.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="IVD26_001976"
     CDS             complement(3431..4999)
                     /locus_tag="IVD26_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAP6079917.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="IVD26_001977"
     CDS             complement(5003..5413)
                     /locus_tag="IVD26_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAP6079918.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="IVD26_001978"
     CDS             complement(5410..6333)
                     /locus_tag="IVD26_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAP6079919.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="IVD26_001979"
     CDS             complement(6330..7208)
                     /locus_tag="IVD26_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAP6079920.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="IVD26_001980"
     CDS             complement(7195..8532)
                     /locus_tag="IVD26_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAP6079921.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="IVD26_001981"
     CDS             complement(8535..9638)
                     /locus_tag="IVD26_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP6079922.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="IVD26_001982"
     CDS             complement(9712..11220)
                     /locus_tag="IVD26_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP6079923.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="IVD26_001983"
     CDS             complement(11186..11878)
                     /locus_tag="IVD26_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP6079924.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="IVD26_001984"
     CDS             complement(11900..12874)
                     /locus_tag="IVD26_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6079925.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="IVD26_001985"
     CDS             13174..14046
                     /locus_tag="IVD26_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6079926.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14628..16508)
                     /locus_tag="IVD26_001986"
     CDS             complement(14628..16508)
                     /locus_tag="IVD26_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6079927.1"
                     /translation="MDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNL
                     FWQKKNKGIEMVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFT
                     TQTVKNKEQPTVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMI
                     RNLRIGLVAVSLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQS
                     VSRIIGEKEALSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYT
                     ALVQIDLLEDSHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDA
                     EASKKVMEYCRLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGP
                     SSIIFYQEIVPAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNP
                     LSREVVSVRLINELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLP
                     ITECSQAITDHEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGE
                     KFGDFVQNHRLEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKK
                     YL"
BASE COUNT         4926 a         3508 c         2729 g         5590 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagctt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattaaacgg cgtttatctt
    14521 gttgattctg cggcaataaa atcagccagc agcaaaacat gaagtgctgt tttttgctgt
    14581 cctcttttat tgcttgaatc agatcacaag aaaaacagcc tcttgattca caaatatttt
    14641 tttcgatatt ctcccggcgt aatcgattcc ttctttttaa agaaacgaat aaaattttgc
    14701 ggatttcgat attgcaatct ttctgcaatc tcttttacgg agaggttagt ctctttcaac
    14761 catttttttg ctacctctaa acgatgattt tgaacaaaat caccaaattt ttctcctgtt
    14821 tcctttttaa atacattact taaatagtta gggttataat gcaacctatc agcgatcaca
    14881 tctaaagaca gatcacgatc atattctgtg tagacgatat gcataatatt ctccgacaaa
    14941 tttttaaatt catgatcagt gattgcttga gagcattctg tgattggcag aactaattgt
    15001 tctaaaacaa gtttttctag ttctttggga tgataattgt tcagtgcttt tacataaatt
    15061 tgtttcatgt tatcaaagtt ttttgaatct actcccaata actgtcctaa ttgaacgagt
    15121 tcattgatca agcggaccga aactacttcc cgactcaaag gatttttatt ttgtgcaaac
    15181 aatgcatcaa tcaattcatg tactaaattc ttcacttcct gatttccaga acgaatggct
    15241 tcaaacaatc gattttgttc ttctatcgga tatctaataa gtgttttttc atgagcagca
    15301 ggaacgattt cctgataaaa aataattgaa cttggaccag tatttacacg ataatacagg
    15361 gcttcttttg cccgatcaac cgattgcttg ctttcattca gcgtttcgaa ccggttactg
    15421 atgcctatac tgatagttaa attcaagtat tcttttacac gtttttgaat gagtcggcaa
    15481 tactccatga cttttttgct tgcttctgca tcatctttat ccattcgata aatagtggct
    15541 tgcatttctt cattcaaaac gatcggcagc attcgatttt cctttggcac aatttccgtg
    15601 atcatgttgt tgatcgctaa aagtagcaaa tcacgctccc caccgtgact atcttctaac
    15661 agatcgattt gaaccaaagc tgtataatag cagtcatttt gagaactata accaaattgc
    15721 tgcaaccgct gatctagttc tcgcctttct actcgatttc taaataaact aagtacaaat
    15781 agcgtttcca gctgtggctt ttgggtaact aagtgtgcac ttaacgcttc tttttctcct
    15841 atgatccgac tgactgattg agcgaccaaa tctagttctt tcccactgaa tccttttgat
    15901 ttaagattca gacgttcctg tatttgagaa atcggacggg caaatctgtc cgaaaataag
    15961 taggaaaaaa gaccaatgag tcctaccagt gttaaagaca ctgcaactag cccgattctc
    16021 agattgcgga tcattgcgcc aattgcacta gagtcaactt ctaatctgta aatccaatta
    16081 ttataatctg atttcagtac tatatacgtt ttatcttttt ctcttatcac tttcagctga
    16141 ttgtaatcta gatccacgtc cgttaataca gttggttgct ctttattttt tactgtctga
    16201 gtagtaaaaa ggttgccaac ttcgttttca atagaaagta tgtcttctcc actttcacca
    16261 acaacttgtt ctattgtatg tttctctatc gtagcaattc ccaatgcata tttttctttt
    16321 tcaaacattg gcaaagaaat caccatttcg attcctttgt ttttcttttg ccaaaataaa
    16381 ttatttttgt tatttatgta cttctgttga tacttttcaa cttcctcttc ggtcagttga
    16441 ctcaacgatc cattgattac tccccattta ccagccaaac tgactaaatc ataattatta
    16501 tcatccataa caatcgtttc tataaaattt agttctttcc tgatttcaga ataagtggag
    16561 taatctgtat atgtcagcgg atgcttgaat atgtccgaga aatttttggt cgaaccatac
    16621 gtagaaaacg aatattcaat cgttctaatt ttccattcaa cgttagtttt aacttgcctg
    16681 agcaaattct ttttgtctgt taaataactc gattcgatcg attcataggt attctggtaa
    16741 atgaataaac taa
//
LOCUS       DACBYO010000063        16510 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.063, whole genome shotgun sequence.
ACCESSION   DACBYO010000063 DACBYO010000000
VERSION     DACBYO010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.063"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(24..722)
                     /locus_tag="IVD26_001987"
     CDS             complement(24..722)
                     /locus_tag="IVD26_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAP6079928.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(715..2067)
                     /locus_tag="IVD26_001988"
     CDS             complement(715..2067)
                     /locus_tag="IVD26_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAP6079929.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2290..3690)
                     /locus_tag="IVD26_001989"
     CDS             complement(2290..3690)
                     /locus_tag="IVD26_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAP6079930.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3851..4588
                     /locus_tag="IVD26_001990"
     CDS             3851..4588
                     /locus_tag="IVD26_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAP6079931.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4713..5192
                     /locus_tag="IVD26_001991"
     CDS             4713..5192
                     /locus_tag="IVD26_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAP6079932.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5189..5956
                     /locus_tag="IVD26_001992"
     CDS             5189..5956
                     /locus_tag="IVD26_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079933.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6186..6755
                     /gene="lepB"
                     /locus_tag="IVD26_001993"
     CDS             6186..6755
                     /gene="lepB"
                     /locus_tag="IVD26_001993"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP6079934.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6859..7461)
                     /locus_tag="IVD26_001994"
     CDS             complement(6859..7461)
                     /locus_tag="IVD26_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP6079935.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7567..8036
                     /locus_tag="IVD26_001995"
                     /pseudo
     CDS             7567..8036
                     /locus_tag="IVD26_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8142..8726
                     /locus_tag="IVD26_001996"
     CDS             8142..8726
                     /locus_tag="IVD26_001996"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAP6079936.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8729..9802
                     /gene="prfA"
                     /locus_tag="IVD26_001997"
     CDS             8729..9802
                     /gene="prfA"
                     /locus_tag="IVD26_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAP6079937.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9795..10634
                     /gene="prmC"
                     /locus_tag="IVD26_001998"
     CDS             9795..10634
                     /gene="prmC"
                     /locus_tag="IVD26_001998"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAP6079938.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10627..10806
                     /locus_tag="IVD26_001999"
     CDS             10627..10806
                     /locus_tag="IVD26_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079939.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10828..11853
                     /locus_tag="IVD26_002000"
     CDS             10828..11853
                     /locus_tag="IVD26_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAP6079940.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12044..13288
                     /locus_tag="IVD26_002001"
     CDS             12044..13288
                     /locus_tag="IVD26_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAP6079941.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13441..14388
                     /locus_tag="IVD26_002002"
     CDS             13441..14388
                     /locus_tag="IVD26_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6079942.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14522..15151
                     /gene="upp"
                     /locus_tag="IVD26_002003"
     CDS             14522..15151
                     /gene="upp"
                     /locus_tag="IVD26_002003"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAP6079943.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15290..15532)
                     /locus_tag="IVD26_002004"
     CDS             complement(15290..15532)
                     /locus_tag="IVD26_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079944.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15653..15725
                     /locus_tag="IVD26_002005"
     tRNA            15653..15725
                     /locus_tag="IVD26_002005"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15686..15688,aa:Thr,seq:cgt)
     gene            complement(15844..16482)
                     /locus_tag="IVD26_002006"
     CDS             complement(15844..16482)
                     /locus_tag="IVD26_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP6079945.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
BASE COUNT         5631 a         2947 c         3319 g         4613 t
ORIGIN      
        1 tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat
       61 tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt
      121 cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca
      181 gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct
      241 tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct
      301 tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga
      361 tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc
      421 aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa
      481 gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg
      541 ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc
      601 gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta
      661 tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc
      721 acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac
      781 agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat
      841 tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag
      901 acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc
      961 ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt
     1021 ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac
     1081 ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt
     1141 gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc
     1201 aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata
     1261 cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt
     1321 gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt
     1381 tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg
     1441 acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc
     1501 atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga
     1561 atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt
     1621 ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa
     1681 gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag
     1741 gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc
     1801 ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat
     1861 attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg
     1921 gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg
     1981 taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc
     2041 aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat
     2101 aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa
     2161 gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa
     2221 cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat
     2281 attcccattt taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt
     2341 ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag
     2401 tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc
     2461 agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt
     2521 agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac
     2581 tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact
     2641 tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc
     2701 gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt
     2761 gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata
     2821 aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc
     2881 caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa
     2941 tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca
     3001 ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat
     3061 caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa
     3121 cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca
     3181 acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg
     3241 aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg
     3301 ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa
     3361 aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc
     3421 cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt
     3481 cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg
     3541 ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca atatataata
     3601 aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg
     3661 cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct
     3721 accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag
     3781 ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag
     3841 gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa
     3901 ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa
     3961 gatattaata catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca
     4021 atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt
     4081 gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca
     4141 tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa
     4201 ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt
     4261 agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac
     4321 catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat
     4381 ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt
     4441 gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc
     4501 caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac
     4561 atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat
     4621 aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa
     4681 caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc
     4741 caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt
     4801 ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt
     4861 cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta
     4921 catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa
     4981 gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa
     5041 gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca
     5101 cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa
     5161 cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt
     5221 gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat
     5281 tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca
     5341 aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt
     5401 tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt
     5461 tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg
     5521 aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca
     5581 attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga
     5641 actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt
     5701 caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga
     5761 aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt
     5821 catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa
     5881 attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag
     5941 aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta
     6001 ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa
     6061 gataagacga acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa
     6121 agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt
     6181 aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt
     6241 tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta
     6301 cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata
     6361 ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta
     6421 tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg
     6481 atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat
     6541 atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact
     6601 ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa
     6661 aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc
     6721 gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac
     6781 atgttttttg tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac
     6841 tttttttgca atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt
     6901 gttcataaat agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt
     6961 tttttccaat cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact
     7021 aatttgttca ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc
     7081 ataaagtttt gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag
     7141 gatgagatta gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac
     7201 atttttcaga tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc
     7261 atcggcaatg atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc
     7321 gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc
     7381 ttcgcgaata atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga
     7441 atcaaaaata ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta
     7501 ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga
     7561 aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa
     7621 atattactag acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag
     7681 gaatcaagta aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc
     7741 actctttcac agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa
     7801 aagactatca tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag
     7861 caaaacatta caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg
     7921 atcaaactat ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt
     7981 tatgggatga atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa
     8041 tagatttaat actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca
     8101 agtataatac cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta
     8161 agtatggcgc aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg
     8221 aagaacaaaa taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag
     8281 gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag
     8341 acgtatttga cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag
     8401 cgcaattctt aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata
     8461 ttccggttat ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa
     8521 aatatttatt gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc
     8581 acaaaaaagc aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc
     8641 aagtgcaaat tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc
     8701 catcaatgat tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg
     8761 ttatgaagag cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt
     8821 tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta
     8881 taaagaagta gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga
     8941 tgaaatggct gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt
     9001 agaagaaaaa atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat
     9061 catggaaatc cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt
     9121 caatatgtac caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa
     9181 cgttaccgga atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata
     9241 ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc
     9301 gcaagggcgt atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt
     9361 agagatcgat attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg
     9421 cggacagcac gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat
     9481 cgttgttgct atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat
     9541 cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa
     9601 tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc
     9661 gcaaaatcgt gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt
     9721 agcagggaaa ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact
     9781 ggaagctatg caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt
     9841 ttttagagga tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac
     9901 aatggaaaaa acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc
     9961 ggttgatcga aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag
    10021 gatatgcaga tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac
    10081 cagaaacaga ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag
    10141 tgatagatat tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa
    10201 attggcatat atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg
    10261 ctcagaaaga aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg
    10321 atcagcaatt tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac
    10381 tgatggatga aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg
    10441 gattagctat ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa
    10501 agattttttt agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag
    10561 catttccaga taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc
    10621 aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa
    10681 cacttatttg acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg
    10741 acaaatagat tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat
    10801 gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg
    10861 caagaggcag ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta
    10921 tacggattgg gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa
    10981 gggagaccgc aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag
    11041 tatgtggaca actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca
    11101 ttaactttga tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta
    11161 tccacagctg catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc
    11221 ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca
    11281 gatcatgtat atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg
    11341 cgaattggtg tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt
    11401 ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct
    11461 attgatcagc atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa
    11521 cactactcac ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt
    11581 caatgggcaa aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat
    11641 caagtgcgga cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg
    11701 gctaaaggat tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg
    11761 atttttgtac aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa
    11821 aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta
    11881 gtatgataca atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta
    11941 atcgtaatag aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg
    12001 taggaaaata aaattgtagg aaaataaaaa ggagctgttg tttgtggtag attacaaaac
    12061 gtttgaccct gatctttggg ctgcgatcgc caaagaagaa gaaagacaag aacataattt
    12121 ggagctgatt gcctctgaaa actttgtctc cgaagcagtg atggctgcac aaggaagtat
    12181 cttgacaaat aaatacgcag aaggttatcc agggcatcgc tattatggtg ggtgtgaatt
    12241 tgtcgatatc gttgaaaatt tagcgattga ccgtgcaaaa gaattattcg gagcgaaatt
    12301 tgcgaacgtc cagcctcact ccggctctca agccaacacg gctgcttatc tcgctttggt
    12361 agaaccaggg gacacgatct taggaatgga tctttccgca ggcggacatc taacacatgg
    12421 atcaccagtc aacttcagtg gcaaaaccta tcactttgtt gcttacggtg ttgatccgac
    12481 aacagaagtt attgattata atgtggtacg tattttagct agaaaacatc aaccaaaatt
    12541 gatcgtagca ggtgccagtg cttacggacg aacgatcgac tttgcgaaat tcagagaaat
    12601 cgcagatgaa gtaggcgcaa aactgatggt agatatggca catatcgcag gattagtagc
    12661 agcaggactt catcctaatc cagttcctta tgcagatatc acaacgacta ccactcataa
    12721 aacattgcgt ggccctcgag gcggcatgat tttgacaaac gatgaagcat tagcaaaaaa
    12781 aataaatagt gcggtatttc ctggtattca aggcggccct ctagagcatg tgattgcggg
    12841 taaagcagta gcattcaaag aagcattaga tcctgcattt aaagaatata gtgaacaaat
    12901 catcgccaat gcaaaagcaa tggtcaaagt tttcaatcaa gcaattggaa ccagagtcat
    12961 ttcaggggcg acagataatc atctgatgtt gatcgatgtt cgcgagttag gtataaatgg
    13021 aaaagaagca gagagcattt tggacagtgt gaatatcact gtaaataaaa actcgattcc
    13081 ttttgaaaca ctaagtccat tcaaaacaag cggtattcga atcggcacgc cagcaatcac
    13141 tactcgcggg ttcaaagaag aagatgctgt aaaagtggct gaactagttg tcaaagcatt
    13201 acaagcaaaa gatgataacg ctcaactaga cgaagtcaaa acaggtgtac gcgaattaac
    13261 tgaaaaattt ccgttgcata aaaaataaaa atttaaattc cattagtaaa cagaaaagtt
    13321 caatgttggg cttttctgtt tattttttgg gaaaacggat tctttgacaa tatcggtgat
    13381 gctctctagt atatgaggtg taattttagt cttcacacta aatctcaggg aggaaaagtc
    13441 atgactgatc gtatctcgtt agaaaaggaa gcagtagcat tcagtgatgc aaatgcgcct
    13501 catccgcgta tctatgaact agcaccggaa gaaggaagag ttttactaga agaagtacaa
    13561 gaatcacctg tgaacaaata ttccgtcgat attgaagact tgatggtgga tactggcgaa
    13621 tggggaaaac tcaatattcg tctcgtacga ccagaaggga atatggataa attaccagtt
    13681 attttttata ttcatggagc aggctgggtt tttggcagtg ctcaaaccca tgataaattg
    13741 atcagagaac ttgcggttcg tacgaattcc gtcgttgtct ttccagaata tagtcgatca
    13801 ccagaagcaa aatatccaac agcaattgaa caaaattatg ctgtgttgca acagctgaat
    13861 aaattagcca agtcaaaaaa tctggatctc gagaatctaa tcgttgcagg agattcagta
    13921 ggtggtaaca tggctacagt catgacgatc ttaacaaaag aacgaaaggg cctcccaata
    13981 tccaagcaat tgctgtatta tccagtcaca aacgctgatt ttgatacaga ttcctatcat
    14041 gaattcggag aaaactattt tttgacaaga gaaggaatga tgtggttttg ggaccaatat
    14101 acgacgaatg aagaagagcg tgctgaaatc acagcttcgc ctttgagagc aaatataaat
    14161 gaactaaatg atcttccttc agcaatgatt ttaacgggag aagcggatgt attaagagat
    14221 gaaggtgagg cttatgcgcg caaacttcgt gatgcagggg ttcctgttac acaagtacgc
    14281 ttccaaggaa tcatccatga ttttgtcatg gtaaatgcta tggatcagac aaaggcaacg
    14341 cgtgcagcaa tggcattatc tacttcttgg atcaagaaaa aagaataagc tttgcttgtc
    14401 cgcaggaaaa cttcttttca aaaacggatt ttcttaggaa aaatggcgag tttgactagt
    14461 caatcacttg attttgtttt acaattaaaa agaaacgaca gaacaaagga gagcttaaaa
    14521 aatgggcaaa tttcaagtga tcgatcatcc attgattcaa cacaaactaa ctattattcg
    14581 ggacaaaaac tgcggaacaa aggtttttcg tgaagtagtc gatgaaatcg ctatgttgat
    14641 ggcatatgaa gtatcacggg atatgccatt ggaagacatc gtgatcgaaa caccgatcac
    14701 tgaaacaaca caaaaaacgt tgtctggtaa aaaagtagcg attattccaa tcttgcgcgc
    14761 aggtattgga atggttgacg gtatcttgga attgattcca gctgctaaag tgggacatat
    14821 cggtctttat cgagatgaag aaacattgga accacatgaa tatttcgtca aacttccaga
    14881 agacattgat gcacgtcagt tgtttgtagt agatccaatg ttggcaacag gcggatcagc
    14941 aatcatggca atcgatgcat tgaaagaacg tggcgcgtcg aacattaaat ttgtttgttt
    15001 ggtagcagca cctgagggag taaaagcttt gcaagaagcg catcctgata ttgacatcta
    15061 tacagcttct ctagatgaaa aattgaatga acatggttat atcgttcctg gactagggga
    15121 tgcgggtgac cgtttgtttg gtacaaaata agtaaatacg aaaaagggtg tgacacaact
    15181 tttgtcacat ccttttttgg tcatttttaa cgtttgatgc agaacagctt tttcacagct
    15241 ttcgtttgca tataaaaaaa ccatcccaaa aatgcagaga tggtcaaatt caaatctttt
    15301 ttagttcttt gtagttaacg attactacac ccttactttg cgtcatcaag ttcgcatttt
    15361 ctgcagtttc atcaatctca acaacagcgg aatttttcaa ttgctttgaa atcgttccag
    15421 tttgcgactt gccgtgaatt gtgaacatta cgtgagtatt gatcttgaat ttttcaccaa
    15481 tttccgatgg tacgatagtt gtatcaaatt ttccaaaagt tgccattttc ataaaacctg
    15541 cctttcacat caattatacc acgttttatg aaaaatatca tgaaattaaa ctaattttcc
    15601 atcggactct ttacaatcag ccaaatagag tatataattt cttttggata aggccagctt
    15661 agctcagttg gtagagcaac gcactcgtaa cgcgtaggtc gtaggttcga tccctatagc
    15721 tggcattaaa agagaagaca gatatatcaa ggatttttaa tccattgata catctgtctt
    15781 tttgtttaaa ggaaataaag tatgctttct tagcaataga gcatgtatta tttctataaa
    15841 aatttaggag aataaaacga ctagcaatat agctgtgaaa tcaaatatca catgaactgc
    15901 ccaacttgta atgatcgagt tgcttttaat ggcagcttgg ttgaataaca atcttgccac
    15961 cccttgtatc aaaaggatgt gtgctacagt gtgtaaaata tttccattat cataagtact
    16021 gtaatggata aatccaaaga tgattgctga caagaaacta gcgacaggaa tgctgaactt
    16081 actagaaaaa atagcgagaa aatacactga gaacaattct tctccaagta tcatgatagg
    16141 caaaataata aataataacg ggctgaaagc ctcatttatt ggattgcctg ttaaacccca
    16201 tttcaaaatt tgttgcaaaa ataccgagac tgcggcactg attactacat tgataaaaaa
    16261 atatttggct atatttttga caggagcgac aggtttcgag aacatttttt tcgtatcttt
    16321 tttaccaaaa acaagtgtaa atgctataaa tccagtgata gttaaagaaa aaatgctaat
    16381 aatggatggc gcaaatagca accctaacaa accgagtaca acgacaatag tgcccaatat
    16441 ccctttttta agttctattt tttttcctaa aatgttattc atgataataa ctcctactat
    16501 tcagtttttg
//
LOCUS       DACBYO010000064        16332 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.064, whole genome shotgun sequence.
ACCESSION   DACBYO010000064 DACBYO010000000
VERSION     DACBYO010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.064"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..468
                     /gene="scm"
                     /locus_tag="IVD26_002007"
     CDS             <1..468
                     /gene="scm"
                     /locus_tag="IVD26_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAP6079946.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTS
                     DSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNF
                     NLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(623..1609)
                     /locus_tag="IVD26_002008"
     CDS             complement(623..1609)
                     /locus_tag="IVD26_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAP6079947.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1632..2198)
                     /locus_tag="IVD26_002009"
     CDS             complement(1632..2198)
                     /locus_tag="IVD26_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAP6079948.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2212..2628)
                     /locus_tag="IVD26_002010"
     CDS             complement(2212..2628)
                     /locus_tag="IVD26_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAP6079949.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3085..5019)
                     /locus_tag="IVD26_002011"
     CDS             complement(3085..5019)
                     /locus_tag="IVD26_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP6079950.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5321..6256
                     /locus_tag="IVD26_002012"
     CDS             5321..6256
                     /locus_tag="IVD26_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAP6079951.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6346..7449
                     /locus_tag="IVD26_002013"
     CDS             6346..7449
                     /locus_tag="IVD26_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAP6079952.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7462..8415
                     /gene="menA"
                     /locus_tag="IVD26_002014"
     CDS             7462..8415
                     /gene="menA"
                     /locus_tag="IVD26_002014"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAP6079953.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9350..10696)
                     /gene="gor"
                     /locus_tag="IVD26_002015"
     CDS             complement(9350..10696)
                     /gene="gor"
                     /locus_tag="IVD26_002015"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAP6079954.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10830..12071)
                     /locus_tag="IVD26_002016"
     CDS             complement(10830..12071)
                     /locus_tag="IVD26_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP6079955.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(12089..13012)
                     /locus_tag="IVD26_002017"
     CDS             complement(12089..13012)
                     /locus_tag="IVD26_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP6079956.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13233..15725)
                     /locus_tag="IVD26_002018"
     CDS             complement(13233..15725)
                     /locus_tag="IVD26_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAP6079957.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15732..16199)
                     /locus_tag="IVD26_002019"
     CDS             complement(15732..16199)
                     /locus_tag="IVD26_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAP6079958.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         4801 a         3407 c         2905 g         5219 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gtgacagtac agatactacc tctaccacaa gtgatagctc agattcatct
      121 accactacaa gtgatagcac ggacacgtca gcttcaagtg acagtacaga tacatcctct
      181 accacaagtg atagctcaga ttcatcaact tcaagcgata gtacagacac gtcgtctacc
      241 acaagcgata cacgtcatgc aagtgtctcc ttctcaaaaa caagttcgga taacaggacg
      301 aactttaact taactaataa aacaagcaat gacaatggaa acaaatcaaa aagagcactt
      361 cctaaaactg gaagtcaatc gaataattgg ataacactcg caggcgttat attacttgta
      421 atcggtttaa gaatcacttt tatgagttat aagaaatcga aaaggtaaaa aaatattcaa
      481 gataaaaaag agcaacgtcg ctaacggacg ttgctcttta tttttgcttt ttatcataaa
      541 tacaagaact acaattcaat ttgtcaaaaa acacgtagat ttccttctga gaaatttatt
      601 tacgtatcga acctttccct attcagtctt tgcgatccaa aatcagttgg gtaagggaaa
      661 agagattctc ttttgttcga agagaggtgg caggtaattt ctttatttcc ttcaaagcct
      721 tttctgtgta agaggccgct aacttcctag cttcttccac gcctcctgta tgttcaacga
      781 ttttgcgtac ggcgtcgaca tcttcttctg tcattgccgc tttcttctct aaataaggta
      841 gtagctttgg tttgtttttt tgcaaagagt agatcaacgg taaagaatag accccttgac
      901 gcatgtcttc tagtacaggt ttgccgattt cctggctctc ttttgtataa tctaaaatat
      961 catcgataat ctgaaaggcc atcccgatag aaagtccgat atctcctgct ttttttgcga
     1021 agcgctcgct tgttccactt tcaaaagcgc caacagaaca acttaattgg aacagttcag
     1081 ctgtcttacc tgaaatattt tccaaatatt cttttacaga aagttcataa ttatagcgat
     1141 catccatctg ccctaattcg ccattcaata ctttttccat actgcgagaa ttcaattgga
     1201 gacttttcaa ggaagtggag taatcagaca atagtttaaa acagcagaca aataaatagt
     1261 ctcctgcata gacagaaacg acattaccaa actgactacg gatattaggc tgaccacgtc
     1321 gcagatccgc ttcatcaacg atatcatcat ggatcagtgt ggccgtatgg agcatttcga
     1381 tagaagctgc caaagcgatg gctttgtctc gatcttgctc tggtccaaat tgtgagaaca
     1441 atagctgata ggcaggacgc aacagctttc cgccggcatg gatcgtttct ttgattgctt
     1501 gttcgacagg tttgtttttc aggcggacag tttcttccat ccgttttagt gtttctgtca
     1561 attctttact taaagcagga tagttttccc acattggatg tagcttcata aaaaaactcc
     1621 ttgtgtgacg attatttttt ggtaaacatt gggctccatt tttgtttggt tccctgctca
     1681 taatcttttt ggaatcgttg aagtgtctgc acatgtcgta aaagataatt cgctgcgatc
     1741 ccgattgcaa tccctgataa aatccctaaa actgaaagga ctggcaagta caacatgact
     1801 gtccatgatt gtgcaatgaa agaagccatc aaaagctgtc cgacattatg catgaaaccg
     1861 ccggccgcac taattccgat gatactgaca cgttttggtc ctaattgctt gaccaataac
     1921 attccaaaat aactaagcaa agcaccactc atactataaa ggaatgtgga aatcgttccg
     1981 cctagcaaag tagtcaggaa tagtcgtagc caaagtagta agaagctgtc ttgttttttc
     2041 atggtaaaaa tggcaacgat cgtgattaga ttggctaagc ctagttttgc accaggcgca
     2101 aaagaaaaag gataagggat catattttcc aataaaccaa tgatcactcc ttgtgcaaca
     2161 agtagcgaaa tataaatcat tttttgtaat ttactcatgg tgtgtaaagg tctaataaat
     2221 cagactgtct tcgtcacctc catctgttga acggacttcg atcactaatt tatgtggcaa
     2281 acagacgatg gtttcgccat ttttcgttgc ccagcctcga cgtacgcaga tctggtcatc
     2341 gcaatctgct tcttttatcc gtactcgatc gccatctatc tcgatcaagt tataatctcc
     2401 gtgttcatct ttgtaagtat atgtgttgct ctcttctcca gccatcaaag ggaatgtttt
     2461 gatttctgtg ccatccacac gcagtaccgc ttctttttct gctgttgcgg tgttttgctg
     2521 aagaccaaaa atcatgactg gtaaaaaaga aagaacagtc aaaagcaaaa taataaaaac
     2581 atcccaaggt ttgagcagac ttttttcagc aaattcttta aggctcattt ttgttctcct
     2641 ttttccagat taactcaccc aattttagca taaaaacaag aggttgtgac acctgtgtct
     2701 tgctttgagt aataagaacg aagaatagaa aacagctttc catgttttct aattctttgg
     2761 gcttattacc gagaagcagc aggtggaaca ccgtttataa caagaggttg tgacagaagt
     2821 gggcaacttc aagaaataag aaggaattta cgaaaattac ttttcaagtt tttgtgaaat
     2881 ttcggcttat ttttcgaaga agctacttct ggaacaccgt ttataacaag aggttgtaac
     2941 agaggttgtg acacctgtgt cttgctcatg gaggcttatc tcgggcatct tattccttta
     3001 attttacata aaaaggaggc tgtgacggtt tgtctcagcc cctttctatt gaaatcttgc
     3061 attcaaataa cgttctttat ctatttattt cttgccgtac tgggaacttg gtctaccgta
     3121 ccaccaatta cctagtgtac gttgtagcca tggaattacc cagcgatcca acccaatcgc
     3181 acgtccggaa ccgttcatca atgcgaaagc aacaaaaatg aaccaaatgt ttacccagta
     3241 aaacatgcct gataagcaga acgtgatcac caatacaatc gttgtcgcac tgcatagcca
     3301 tgtgaataat ccagcaatca atgctaatgc caaggcaatt tcaaagaata ccatgaattt
     3361 ttggaagaac attgctacat cattgtttgg catgatcact tgcatgatct ttgtgaacca
     3421 gtctggtgac ttctcaatca cagccattgg ttcttcaccg tatgcataac tcaaaccaaa
     3481 atgtgcagct tgagtcgctg cttctccggc acttgcccct gctccgctgg cagctgtggt
     3541 tgcatcacca gcagcagaag caccactggc aacatctgtt acattgtatt cccatgtcca
     3601 agggaacaca ctgtttccag tgaaccatga tccttcacca aaccaagtac ttggtttgaa
     3661 cacttcacca ttcccaatga tttttttgga agcttcaacg aaccaaacta aaccatagaa
     3721 aatacgaagt ggcacactcc ataagacatt gccgtaacga gaagaatgtc ctcgagtcac
     3781 gttgcgatca tctttgatat ggaaaaactc atgcattaaa tattggaaca tataataacc
     3841 agaacgaata tcaaagaagt atttcaaatt cacgatatgt ttcattacga tagctaaaaa
     3901 tccgcttaaa tggatcttat caaataggtt agctaccccc catttggcac caatagaaac
     3961 cataaatcct tgatagtttc ctttaaattt atgcttttct ccgcctttga tcgaagccac
     4021 gatattcgct gcggctgtgt gtcctgtttg ttcagcagct tgaacgatct gcggtgtcgg
     4081 tgttcctggg aattcttcat aaaagactaa atcaccaatg atatagatgt ttttatcttc
     4141 gtagcctttt gcctgcatat attcattggc gatcaaccgc tgtccgcgtg ctgattctaa
     4201 tccaaagtca gcagcgtcag aagttccttt gacaccagct gtccaaatca gtgtgtgagt
     4261 cggaatgttg cgtccgtctt tcaatttgat atgatcagca gccacttcta cgattggtgc
     4321 attcaataat aattccacgt tgtgcttacg caaatagcgt tcagcttttg cagcatcatt
     4381 tcgatccaac atattcaaga tcgtcggcat tgcctctacg accatcagtg tgatttcgtt
     4441 tggatctaat ttataatctt tggctaggcg atttttccag tcgatcagtt ccccaatcat
     4501 ttcaataccg gtaaatccag aaccacagac aacgaaagtc agcatggctt tacgcagttc
     4561 atcatctggt tccaatgcag cttttgctac tgtcttctca atatgttccc gaatccttac
     4621 agaatcttca aatgaccaaa gggtgaatcc gtgtgctttg acaccaggtg taccaaagtc
     4681 attcggctct ccgcccattc caaggatcag ctgatcaaaa ggataggaac ctaatttggt
     4741 cttgacgatt tttcgttctt tatcgatacc gattacagtg tctgtgacaa gttgtacatt
     4801 cttttgacga gcaaacaaat gctgcagatc gtattggatt gcttctggtt ctacacgtcc
     4861 gccagctact tcatgcaact cggtcatcat agtatggtac gaatgacgat cgatcagagt
     4921 aattgctaca tcttcttttt tcagtttctt tgccaagtat tttgtagctg aaacaccggc
     4981 atatcctgct cctacaacga caatattttg ctttgccatt gatcatccgc tccttataga
     5041 ctatctatat aatgaatata tgataattct tttagtttga tacttattac acaatctcca
     5101 tatattatat agatgttctg ttcttttgtc taactccttt tggatttttt tcaaatttta
     5161 aaataaagcg ttttttcacg aaatttgctg aaagaaaacg tttgaaatat tacatgggtt
     5221 atttatcaaa aatagttgac ttataggcta aaaagattag aatgtataat gaatcacaaa
     5281 gaaaaattgt ggactagaaa tggaatggtg gggtattaaa atgaagaaaa aacgttttgt
     5341 aactggattt gccgtattag cattttcagc tctagtgtta ggcgcttgcg gcgcagatga
     5401 caacggaagc tcaaactctt cttctgaatc atctacagca caatcttcga ctgcaaaaag
     5461 cacaacagaa tcatctgcaa aagttgtagc tggcggagat ttgcaagacg gcacatataa
     5521 attagaagaa aaaaattatt caaatggtta ccgtgcagtc tttgaaatgg ttgtaaaaga
     5581 cggcaaaatc actgaatcaa aatatgataa cgtcaatgaa aacggcgaat caaaaacaaa
     5641 agatgcagaa tacaacaaaa acatggaagc aaaatctggc acaaacccag aaaaatacat
     5701 tcctgagttg aatgaccaat tcttaaaagc acaaagcgca agcggtgtgg aagtcgtaac
     5761 tggagctact cactcatctg aaagcttcca aaactacgca caacaattga tccaagctgc
     5821 tcaagctggt aacacagata caatcgaaat cgacaatggt gctgatttga aagacggcac
     5881 ttacaagctt gaagaaaaga actactctaa cggctaccgt gtgcaattcg aaatgacagt
     5941 tgctggcggc aaagtaactg aatcaaactt tgattatatc gacaaagacg gtaaatcaaa
     6001 acaagatgat acagaatata atgaaaatat gaaagcaaaa agcggtacag aaccaaaaac
     6061 ttacatccct actctgaacg acgaattcgt caaagcaatg ggcgaagaag atggctcacc
     6121 tgctaatgta gaagttgtta caggtgctac acacagctca cattcattca tcatgtacgc
     6181 acaacaatta gtgaatgcag ctgaaaaagg cgacactcaa acaatcgaag tagataatat
     6241 cgtaacagaa aaataatcac ataatcatac taataaaagt tggagggtgg gacgatagcc
     6301 agattaggca gtcgtctcac ctttcaaaat gaagagagga aaaagatgcg gaaaaaacta
     6361 ctattttcct taatcacact gggcatctct tttatggtgc taactggctg cagcaactca
     6421 gcaaataaaa caaccactga aagttcagca gctaccaaga tattgaaaga tccatattct
     6481 gatgaacagt tcttgttagg gacttacgtt cgtatccgtg tgtatgatga aggcaaagaa
     6541 tcagcattga aacctgcctt cgatcgagta aaagaacttg gtgataaaat cacgatcaat
     6601 caaaaaggtt ctgagatcga tgaagtgaat gagcaagctg ggatcaaacc agtaaaagtt
     6661 tctgatgacg tctacacgtt agtcaagcgg gcctacgaat atagccaaga ttctcaaggc
     6721 ggattcgata tggcgattgg tgcaatcaca caattatggc gaatcggttt tgatgacgcc
     6781 agaaaacctt cccaagaaga aatcgatcag gcattgaaat tagtggatta tcataagatc
     6841 gaactaaatg acaaagaaaa aactgtttat ctaaaagaaa aaggaatgat catcgattta
     6901 ggtgcaatcg ccaaaggtta cattacggac gaagtagtga aagtcttgaa aaaacaagga
     6961 gtgaccactg ccatcgttga cttgggcggt aatgtctatg tcttaggcca cagcccaaga
     7021 ggcgaaaacc aagactggac agtcggcatc caagatccga acatggctcg cggatctgtt
     7081 ttaggttcta ttaaagaacg gaacaaaaca ttagttacct ctggaattta cgagcgttat
     7141 ttagaagtag atggcaaaaa ataccatcat ttgtttgatc caaaaacggg ttatccgttc
     7201 gacaatgata tcgcaagtgt cacgatcata acagataaat caattgatgg tgacgggttg
     7261 tctacagcag tcttttcaat gggtgtgaaa aaaggactgg aatacgtcga aagcgaattg
     7321 aataacggga cggaagcgat cttcgtgaca aaagacgata aagtatatgt gaccgatcca
     7381 atcaaagaca ccttcaaatt atcggaggac tcccattaca cgatgggtga ccgttctgaa
     7441 ctaaaataag gagtacgaac catgacacta aaaatctttt tagaagtagt tgaaatacga
     7501 acaaaggtgg ctagtgtatt tccttttgcg gtaggggtat tattctctat cgcttttttt
     7561 catgagatac attggctaaa cactttttta ttttttattg gaatgctagt ttttgattta
     7621 gcgactaccg ctatcaataa ttacatggat tatgaaaagg ctcattctga agtatataag
     7681 tatgaagaaa atgtcattgg ccgcagaaat ctatctcctg tattgattcg aaacatgatt
     7741 ttagctatga ttgcatttgt ttttgttatc ggcgttattc taacgatcaa tacgggttgg
     7801 cttttacttt tgatgggatt tatctgttgt tttattggag tattctatac attcggaccg
     7861 attcctttat ctcgaatgcc tttaggggaa attttcagtg gggtgactat gggccttgga
     7921 atttttgcca tggtcgttta tgtcaataca ttcggttcag atgtctatga tctgacagtc
     7981 aacttttcat ctggacaatt tgctttggta ggaaatcttt gggctatagc agcaatcgta
     8041 ttagcttcct tacccttggt gtttacgatt gccaatatca tgttggctaa taatttgcgg
     8101 gatcttgacc gtgatattga aaatcatcgc tatacactag ttttttatat cggacgtcct
     8161 gcgggaacag tcttattcca gctattgatg tatgcttgct atttcgtgat tttaatgggg
     8221 ttgttgagcg gtatctatga atggccgatc ttggtcacct tcttgacctt gccaattgtg
     8281 aagaagcatt tggatcaatt caagcaaacg ttaccccagc ctatcagttt cagctattcc
     8341 atcaaaaata tggtcttatt caatgccagt tatgtattgg ggctattact aacaatcatt
     8401 atgcaagcca tttaacagca tgaagaggtt gtgaaaaaac tgccctgcat caagtaataa
     8461 gaacagccaa ataaaaatag ctccttatat ttttcgtttg gttgggctta ttaccgcaga
     8521 tgcaagcttt tgaacaccgt ttatcaggag gttgtgaaaa agtcgcttag tttcgagtat
     8581 taagaaaaat tttgtgaaaa tggctttcca catttttgca taaatttggc ttaataccga
     8641 gaaactggct tttgaacacc gtttatcaga ggttgtgaaa aagtcgctta gtttcgagta
     8701 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaatttgg cttaataccg
     8761 agaaactggc ttttgaacac cgtttatcag aggttgtaaa atcagtgttt tgtcctgagt
     8821 attagagaaa caaatggaaa aatagttcct catattttgc cgttttttga gctaataccg
     8881 aaggacagct gattgaacac tatttgttcg gaaaaagtga ctaactatga cacaattttt
     8941 ttcacagtcc cttttttcac ttgatttgat tcgtaccagc gaacttgacg agaactttct
     9001 tggtttggta actatatggt attcttttaa catcctcgtt tgcttcttct aatttattta
     9061 tacaaagtca cactttttta aacatctgtt cttcgataca tttctatttc ttttaaacat
     9121 cgataccaat attttgaact taagagtgca taccaaatgg attcatttac tcttcgtcag
     9181 ttacgaagat aatcaaaatc tccaacttcc ctacttattt cgttttgaga attatcgaag
     9241 caatcttaca taaataacta aaaaacaaaa aaccagaaaa tcagtatact gattttctgg
     9301 ttttacatgg tttgttcaat aaaaagctgt tggaactgtt aatattaaat tatcgcatcg
     9361 ttacgaattc ttccgctcct gttggatgga tggctactgt attgtcaaag tcttctttag
     9421 ttgcacccat cttgatagcc acggcaaaac cttgcagcat ctcatcgaca ccaacaccaa
     9481 tagcatgtaa gccgacgatt ctttcttctt ttccgacaca gatcaatttc atttcgcatt
     9541 tttggcgata atcatttaat gcaaagtaca ttggggtaaa gcgtgaacga taaactttca
     9601 attcattttc gccatatttt tccaatgctt cttcttctgt caaaccaatt gttgcaattg
     9661 gtggatgcgt aaagacgact gtcggaacaa gtttatagtc aagataagaa tctttctttc
     9721 cattaaataa acgttctgat aaacgtctac cagctgcgat tgcaacagga gtcagatcta
     9781 atttaccgat cacatcacca acagcaaaaa tatgttcatc cgttgtattt tggtatttat
     9841 ctactttgat aaaccctttt ttgtccaatt ccacatttgt attttccaga cctaattttt
     9901 cggtattcgg tacacgtcca ccggcaaaaa gtacacaatc accagttaag gtttcaccat
     9961 tttcaaatag caccgtatat tcgtcattgt ttttagtaat ttctttagca atatgatgtg
    10021 cgtaagtttt tattccagct tcttggtaca tttggatcaa attgtccgaa agcattttat
    10081 caaacgttct aagtggtcgt tcttttcgat atgcccacat gacttcacta cctaaaccac
    10141 gaaatacacc tgaaagttca gccgcaatgt atccagcacc taaaacgatt gctctcttag
    10201 gtaactctgt taattcaaaa aatccatttg aatcaattgc gtattctcca ccaggaatgg
    10261 tcattttact tgcacggcct ccagtagcga tcaagatttt aggagcacga taggtttcac
    10321 cgtttacttc gatcgtttga ctatcgataa aagtagcgta accttttata gcctcgacat
    10381 gattgctatc taatcctctt tgataagcac cgtgtagaaa atcaatatat ttttctcgtc
    10441 tttctactag accggcgaaa tcaacatttt ttaaatctgc ttggataccg taacttgagg
    10501 catctcgttc aattgtttcc aaaatcgtac ttgcttgcca cataactttt ttaggtacac
    10561 aaccgacgtt gacacatgtt ccgcccaatt cattcgcttc aatcagcaaa acttttgcgc
    10621 catgcatccc tgctctgttt gctgaagcaa taccgccaga gccgccacca attacgatgt
    10681 aatcatatat ttgcattttg ttcctcctta ttgaagagat caatcaaaac ctttatttaa
    10741 cgatcctttt tctacagaaa acaagtgtaa cacttttctt gaattttgta tgcgaagatg
    10801 cttaaaacag ggatatatca gctttttcct tatttacgtt ttcggatcat atctccaggt
    10861 ttcaccggct gtgcgactgg catagttaaa atcatcattg gatttggtgc tcggtcaatg
    10921 gattcgcctt cttcattatg cataacttca acggtttgac tgaaatgact gaatcctgga
    10981 ccataaaatt cgatttcatc tcctacagaa aacaagtttc tctgacgtat cgtagcaatc
    11041 tgtgttgcct catcataaga taatacttca ccgacaaatt tatatactgg gattttacga
    11101 cgttcaccga ataattgttc gttttcagtt ggtgtattgt agtaaaaacc tgtagctaat
    11161 tctcgttgtg ctactttcca taactcgtcg atccattctt gcttgcagac atagttttca
    11221 ggatcttcca tataactgtc tacagccgct ttatagacat ttgacaccgt agatacataa
    11281 tggatcgatt tcattcttcc ttcgatcttg aagctgtcta cgccgttttc aatcaattct
    11341 ggaatatgtt cgatcattga catatccact gcactcatcg agaattcttc ttccacttcg
    11401 cctgtatcag ttaaactgtt tcgttcttga ccaaaaggca tatcgaacaa tccatacttc
    11461 cagcgacaag attgagaaca tccgccacgg tttgcatccc gcatcgacat atggttggac
    11521 aatgtgcatc gaccagaata agagatacac atggcaccat ggataaatgc ttcgatttcg
    11581 gtatccgtat ttttacgaat ctctgccact tcctccattg aaacttcacg agctaaaacg
    11641 acacgttcca acccttcttc tttccagaat tccaatgtct caaaattagt tgctgaagct
    11701 tgagtggata aatggatcgg cagacctggg gcttctgtcg cacaaatttc gatcaaagct
    11761 ggatcagaaa caatcactgc agaaataccg acatcacgca aactgcggaa aaattcccct
    11821 gctccatctt catttccttc atgggtgacc atattagcag caacgtatac cttcgcatca
    11881 tgttcttttg caaaagcaac tccttcagcc atttcttcat aagtaaaatt acctgcacgg
    11941 cttcttaaac catatgcatt cccgccaata tatactgcat ctgctccata atggatcgcg
    12001 gtttttaact tttccagtgt tcctgctggc gctaggattt ctggtcgttt caattttctt
    12061 tttactgtca tttctttcat catactcctt atttgatagc agaaggatca atataaaaga
    12121 atcctgtatc taattcacgg ttttcaggat gcaatttact gatttcgcta gtcatttttt
    12181 ccgctttttc ttgatcccag ctaccttcta aaatttgttt ttttgcttcg gcgaatagtc
    12241 gagtgatgtt tacgaatttt tcgcctggag taaataatcc gtccaatttc catgtacagt
    12301 aatgatgctg ataaagttca ttcaattcat tcgagagatt cagatcattg ctggcaaaaa
    12361 tatgtgtgcc atgactatct tcataaatag aataatgtgt ctcttctttt ttaggttccg
    12421 agataaaaag acctctttca cgatcttttt gttcgtcttg tttcgtatag ttatagtaat
    12481 tctgtagcag tggacgtttg gattgatgga tgcatgtagc accatacaca agggtttcta
    12541 caggaatatc gagtttttct tccatcgcct tcatctcttc aaaaggaact tcacgagcaa
    12601 gtactgctcc aactgcgcct tttttcgccc agaaattgat ttgacgtgcg ctcgttacta
    12661 atgtttcagc atcataaata tacggtatac gcaattcagg attttttttc atcgtataaa
    12721 taatacctgt atcaccaact gtgatcacat ctacgtttat ttcttttaaa aaagccaaat
    12781 attcaggtac atttttcatt ttttcaggat gaatgatccc atttacagca atattcgctt
    12841 ttttaccata cttgtgtgct aattctacca attgtcgctg ttcttctcgt gtaaatgaag
    12901 caggcagacg caatccaaat tgctcttcac cgaaatatag tgtatctgca cctgcagcaa
    12961 gcaactgttc tgcttgttca atagtttcta ctgtggttat gagttcgatc ataattttct
    13021 cctcctacaa cttcataata gtagcatagc tctaaaaact ttccaatact tcttctattt
    13081 aaagtcggat ttttgaaaat tatttcacaa aaaatcaaaa taaagttcga tatattctgt
    13141 ccaaatataa aaagagattg tgacaaaaat cttgtcacaa cctcttaatc aagtcttact
    13201 attataaaaa ttcagctaca caggccaagt aactataggg aacctactgt ttccttttta
    13261 ggtccgcgaa cattcaatgt gatcttacct tttgaagcac ctactgttac gtggtcacct
    13321 aaacgaattt ctccgccaag caaagcctcg ctcaatcgat cttcaatttc tttttgaagt
    13381 gcgcgacgga ttggacgtgc accatattca ggatcaaatc cagctttccc gatcacatcg
    13441 attgcagatg gtgtgatttt cacttgaata tcttgttctt tcaatcgttt gataatcgct
    13501 ttgctcatga tttggacgat tgtatggatt tcatctttac tcaatgaatg gaagacgaca
    13561 gtctcatcga ttcgattcaa gaattcaggt cggaaagctt tctttaactc ttctaagata
    13621 cgtttttgca tggctttgtg atctttagta acatcttgga cattgaatcc gacatttttt
    13681 tcttctcgaa tttgtgtcgc tccgatattt gaagtcataa tcatgattgt atttctaaag
    13741 tccacttttc tacctttaga atctgttaaa tgaccatcat ccaatacttg cagaagtaaa
    13801 ttgaaaacgt ctggatgtgc tttctccact tcatctaaga gaatcactga atatggtttt
    13861 tgacgaattt tttctgtcaa ctgtccacct tcatcatacc ctacgtatcc tggaggagac
    13921 ccgattaatc ggcttgtact gtatttttcc ataaattctg acatatcaac acggatcagg
    13981 gcatcttcac ttccaaacat gacttctgaa agtgctttgg ccaattctgt ttttccgaca
    14041 ccagttggtc caaggaacat gaatgaacca attggacgat caggatcttt caatccgctt
    14101 cgtgcacggc ggatcgcacg tgaaactgct ttgacagcct catcttgacc aacgacacgt
    14161 tcatgcagaa gtccttccag ttctaacaag cgttcgcttt cttttttctc caactgctgt
    14221 agagggacac cagtccactc cgatacaact gtagcaacat cttcttctgt tacacgatca
    14281 gaataacctt gctcctgttt tgcttcaatt gcagaaactt tttgcagctt tttacgtagt
    14341 gctttttctt gtctgcgtaa ttgagcagca ttttcaaagt cttgtttttg gatcgctgct
    14401 tccttttctt gtactagttc atcgatttct agtttgatca cagttgattt tgttaagtga
    14461 tcggtttgat ccaaacggac tttcgctgct gattcatcga tcaaatcaat tgctttatcg
    14521 ggtagttgac gagaagtgat ataacgaaca gaaagattga ctgctgctcg tacagcttca
    14581 tctgtgatct ccactccatg gtgctcttca tatcttgtac gtaatccttg aagaatcact
    14641 tctgcttctt caggagttgg ctcatctact tgaatgcgag caaaacgtcg ctctaatgca
    14701 gaatcttttt cgatatattt ttgatattca tctagggtcg ttgctccgat cgtttgtaat
    14761 tctcctcgag ctaacgccgg tttcaagata ttcgaagcat caattgctcc ttctgctcca
    14821 cctgcaccaa ttaaggtatg caattcatca atgaataaga ttacttgacc atcattatag
    14881 atttcgtcga tgaccttttt cattcgatct tcaaattcac cgcgatattt cgtaccagca
    14941 accaaagatc ccatatcaag catcatcagg cgcttttctt gcatgtcttc tggcacttca
    15001 cctaaaatga ttttttgagc taacccttca gcaatggctg ttttgcctac accaggttca
    15061 cccaccagta cagggttatt ctttgtccgt cggctaagaa tctggataag ccgtttcact
    15121 tctctcgaac gaccaacaac tgggtccagc ttgttttctt ttgctaattt cgtcaaatca
    15181 cgtgctaatg aatctagcgt aggtgttcct tgcggtgttt gccgtttatc ttgtacattt
    15241 acatttctac gacgattcat tccttttcca gcagaatcac cagctagccc cattttttgt
    15301 ttcagaactt gacgggcttt tgaaaggctg atacctaagt tgatcatgat tcgagtagcc
    15361 atgatacttt catcttttaa taagctcatc aaaatatgtt ctgttccaac tttttgagaa
    15421 ccagttttct tcacttcgct gctagctaaa gcaaaaactt gtttcattct tggtgaatat
    15481 ggaagaaaga ctcctttagg gtaagaacgg ataccaccat aaccaatcag atgttcaatt
    15541 tcttcataaa tttccgtttc attcaaatcc atttcacgta atacttttcc agcaattcca
    15601 ttttgctcga ccactaaggc tagtaaaaca tgttctgaac taactgattg atgtttcaac
    15661 cgttttgctt cttcttgtgc aatttctaat actgcttggg ctctttcagt aaaaagttct
    15721 tccatctaat ctcacttccc atcttcataa cttaaacgtt ccagaaatgc tcggagaatc
    15781 cgagcacgtg tatgatcttc atattcattg aaattcaatg tgttttttgc aattgcactc
    15841 aacatcaagt ttccttcttt ttttgtaatt atttggtctt cataaagttt ttgaataata
    15901 gcaaaagcat ttttctcact gattgtatca tcaaataact gatttatctg ctcaagtaat
    15961 tgttttttat ctgaaatcct tacttttgca attcgtatat aaccaccacc accacgtttg
    16021 ctttctacta gataaccacg ttggatggta aaacgggtat taatcacata gttgatttgt
    16081 gaaggaacac agttaaagag gtctgccatt tcaatccttc gaatctcgat catttcacta
    16141 ttttccagaa ttttctttat atatgattca attaaatccg aggtattctg atgtgccatc
    16201 ttattcattc cctttgacta atattgacct taattataac gaatttgata atagaaagaa
    16261 agaagaacgc tttttgttaa ataaatcctt tagaatcaac aaaaaaaaat acggaatata
    16321 ctattccgta tc
//
LOCUS       DACBYO010000065        16140 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.065, whole genome shotgun sequence.
ACCESSION   DACBYO010000065 DACBYO010000000
VERSION     DACBYO010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16140
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.065"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            226..894
                     /locus_tag="IVD26_002020"
     CDS             226..894
                     /locus_tag="IVD26_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAP6079959.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1324)
                     /locus_tag="IVD26_002021"
     CDS             complement(1094..1324)
                     /locus_tag="IVD26_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079960.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1451..2833)
                     /locus_tag="IVD26_002022"
     CDS             complement(1451..2833)
                     /locus_tag="IVD26_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP6079961.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2989..4176)
                     /locus_tag="IVD26_002023"
     CDS             complement(2989..4176)
                     /locus_tag="IVD26_002023"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAP6079962.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4183..5214)
                     /locus_tag="IVD26_002024"
     CDS             complement(4183..5214)
                     /locus_tag="IVD26_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP6079963.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5260..6684)
                     /locus_tag="IVD26_002025"
     CDS             complement(5260..6684)
                     /locus_tag="IVD26_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6079964.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            6859..7764
                     /locus_tag="IVD26_002026"
     CDS             6859..7764
                     /locus_tag="IVD26_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6079965.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7855..8532
                     /locus_tag="IVD26_002027"
     CDS             7855..8532
                     /locus_tag="IVD26_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP6079966.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8813..9709
                     /locus_tag="IVD26_002028"
     CDS             8813..9709
                     /locus_tag="IVD26_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP6079967.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9764..11134)
                     /locus_tag="IVD26_002029"
     CDS             complement(9764..11134)
                     /locus_tag="IVD26_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6079968.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11372..12118
                     /locus_tag="IVD26_002030"
     CDS             11372..12118
                     /locus_tag="IVD26_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP6079969.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12115..12954
                     /locus_tag="IVD26_002031"
     CDS             12115..12954
                     /locus_tag="IVD26_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP6079970.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12955..13905
                     /locus_tag="IVD26_002032"
     CDS             12955..13905
                     /locus_tag="IVD26_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAP6079971.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14046..14798
                     /locus_tag="IVD26_002033"
     CDS             14046..14798
                     /locus_tag="IVD26_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079972.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14817..15968
                     /gene="queG"
                     /locus_tag="IVD26_002034"
     CDS             14817..15968
                     /gene="queG"
                     /locus_tag="IVD26_002034"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAP6079973.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5234 a         3009 c         3242 g         4655 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt tgataccgtt
     1381 gactagttct tccatcgcaa aagcagtccc ccattttaat ccaaatggcc gatctcgata
     1441 ctcgttatag tcaatgaatt tttttgctgt ccgtctcatc ttttccacct tctaatccac
     1501 tcataccacc tgcatgcccg ccaacgagag aactacgtgc gatggcgcgt cctccttgca
     1561 agagactatg cgcatggatg attgattgaa agccgtattt ttttctaatc gtatcgacaa
     1621 caaaatcaac tttcgcttca tttatctgct tttcaggatc ttcaaaaagg ttaagctgta
     1681 aacctgtcgc gtatacgagg tcggaacagt tcacgcctac acgccgaata tcctggtagt
     1741 ggtaatgctg gtggaaaatg gtcaataaag catctgcaag atctctgcta gcatttgtcg
     1801 cttcgatttt catttgctgg tgaaacccgg tcttgccatt tggatcaaga tagcctaaag
     1861 agtatcctac ccataagctg actacttgtg tttttgctgc agatcgtctc aagcgagtgc
     1921 cgacttggtc ggccatttct ttgataacga tctcgatttc ttctcgtctt gtataatctc
     1981 tatctaggat ttgactattt ccgatacttt ttgattttgg tgtatattct tgtcccaaaa
     2041 aacttcgatc gatgccccaa gcatgggcat aaagctgagt accgatgacc cctagcttgc
     2101 ttttcaagtg ataataatcc gcgtgagcta aatcataaac agaatgtata cccatttgtt
     2161 tcagacgttt tgctgttcgt ttgccgattc cccaaaagtc agtgatatct gagattttcc
     2221 ataacttttc tggtacatct tcataacgcc attcagcaaa catttgcttt ccgtcttttg
     2281 agccattgtc taaggctagt ttagcaagta gcgggttatc gccaattcct atagtcgtgt
     2341 agattccggt ctgctcaaac acatctttat ggatcagttt agccatgtcg tacgcatttg
     2401 ttttaccaaa gagtgccatg ctatttgtta catcaaggaa gctttcatcg acggaataga
     2461 catgatggtt cgcttcgtct gcatattttt tatagataga attgatttct ctgttctttt
     2521 ccatataata ggccatcctt ggggcaacaa tatataaatc acttggatag gggaagggaa
     2581 gatctctggc acggctgata ttggtgatgc cgtaagcttt ttttgctgca ggactggaag
     2641 ccaagattaa tccgctaccc cgtgtttctg tcgaatcgga cggataggac atgactacta
     2701 atttagttgt aaggggatca agatcctttt caacgcactc tacggaggcg taaaaagatt
     2761 tgcagtcaat acataaaata tctcttgaag gttctttttc ataaacaaat accggatttt
     2821 gattcgccca cataacaatc acctcttcaa cacaattaga acacacgttc tctttccgtg
     2881 tcaataaaaa acagcaattt tcaaatacga gcaaaaggct cacatttgga aattgctgag
     2941 aggttatttt tatctatttg tttttagctg agatcgttga tttttttatc aaacatgaac
     3001 agcttctgga tcgatctttg ttgtcccatt tccaatgtgt gcaacataaa attccggagc
     3061 atagccgaca actttcatgt attcatcata gacattgttt ttgaaggcag gtatattttc
     3121 ttctttgaca agagcaatcg cacagccacc aaatccagct cctgtcattc gtgcacctaa
     3181 gacaccttct tgtttttgag cagcatctac tagtgtatct aattcgatcc cagttacttc
     3241 ataatcatag cgaagagagt ggtgagaatc atttaacagt tgaccaaatg cttctaagtt
     3301 cccagcttct aattcagctt ttgccttcaa agtccgctga ttttcagaaa cggcatggcg
     3361 agctctgcgt atcaatgtat catcgccgat ttggtcaata gttgattcaa attcttcttc
     3421 atctaagtct cctaaagaag agataggcaa agttttttgc aaacgtgcca aggcttcttc
     3481 gcattcgcta cggcgttcat tgtattttga atctgccaat tcccgccgct tattcgtatt
     3541 catgatgacg attgcataac catctagttt cactggaacc atttcgtatt tcagcgtatt
     3601 tgtatctaat aagattgcat gatctagctc accgaagccg atggcaaact gatccatgat
     3661 acctgaattg acaccgatga attcattttc tactttttta cctgtttgga ctagttccaa
     3721 gcgatctgtt tttaaatcaa acagatcttc taatacaaca cctactaata attctaatga
     3781 agcgctactg gaaagtcctg caccattagg gattgttcct tccactaata actcaaaccc
     3841 atgatcgatt gagtgtccag cttcttttaa tttaaggacc attcctttta cgtaatttgc
     3901 ccagtttgct tttttatcat attctagctc atctaaagta aaactaatga caccgatatc
     3961 gtcaaagttt gtggaataaa ctaatatttt attatcgtct cgaggtgctg ctacaccttg
     4021 cgttccataa gtgatggaag cggggaagac atggcctcca ttgtaatctg tgtgttcacc
     4081 aatcaaattg atgcgtcctg gtgagaagta ttgtgtagtt tttttaggtc cgaatgtttc
     4141 ggcaaatttt gtgtttaagc ttcttttgat ttccatgatg agttattcct ttcttgtttt
     4201 gattttgaat tctgttactg tttcaaatac tgatccggct tttaaatgaa tcgaaccaaa
     4261 tgctgagaag cgctctgcac ctggagctgt ttgagtctca aatgtgatgc caccgtgatg
     4321 tgccagtttt cggttgcgca tttctggtgt ttctgtgccg aaatttgcag tgaaaataac
     4381 cacactagaa gcatctgtag caatatctac ttggattctt ttatcggggc tagtcaagcg
     4441 agcggcttct ttacccaagc cggtttcttt taagaaaaat ggatgatcga ttccgtcaac
     4501 aagatttttt tgatccaaat cactagcaaa aacggacgct aattttttag gtatttgaaa
     4561 atcgaaagca cttcctgcag cattttcttt tacccctata ggaatactat ctgttcgcaa
     4621 aggagcataa gcttcgctat tgagccaaag ctcatgttga tcgattgact gagaagcatc
     4681 tcccgtcaag ttgaagtaaa catgatttgt cggattgaat aaagtatctt ggtcactggt
     4741 gccgcgagag gtcactcgcc agatattatc ttttgtcaaa gtatagcgga tttccacatc
     4801 cattgtacct ggaaaaccat gttctccgtc gggacttgta gtagtaaaaa tgacagaagc
     4861 ttcattttcg ccattcaaaa tgacataaga ccattttttt aattcaaatc caggagcacc
     4921 accatgcaga ttatgtccag tttttggatc tgtggctaat tggtaagttt ttccattgag
     4981 agaaaagcgg ccattttcga ttctccctgc ggtgcgaccg atagaagcac cgatatacgg
     5041 atctttttcg atatattctt cagcggtgtc aaatcccaaa actaattctc gatcatttga
     5101 ttttaaactg acgattctag cacctaaatc agagatagaa agtgctagct tgtttttgtt
     5161 ctccaaggtt atcaagtgat aaccttggcc aaaatctttt tctgtaatct tcattttcaa
     5221 gatcctttct taatgggaag gaactactgc atcgtgaagt taatcttcca ttgtatcagc
     5281 tggagccaat ttgttttcca atttctcaac gatttgtgca tgttttttct ctgtcaatgt
     5341 aatcttccaa gcaaaaataa tagcggagaa aatcatcaaa gcagcaggag catagaatgc
     5401 ataagctttg aaagtcgtta cgccatgagc agtgatatca gcagcagtag cattaccagt
     5461 catcccagaa gcgatagcga caaaccctac gatcccgtta gacaaagcac cagcgatttt
     5521 atctagtaaa gggcgaattg atagagtaac agcttcgtta cggataccat ttttccattg
     5581 accatattca acagagtctg tgatcgtcat caaagcggat aagaaaatca attgttgagg
     5641 gaagtagaac aatactagcc cgatgataac gattggcaaa cttgaacctg cgatcgtaaa
     5701 gaaaaagtaa gaagaaatca tcattgcgat ccctccaagg taaacgtagc gacgagagat
     5761 gacgcgtgta agcattggga atagtggaac agctactaaa ccaagtaagg cagcaactag
     5821 accaacgatc caaaattcag ttggttggcc aagtacatat ttgaagaagt agaataatac
     5881 ggcagttgtt gctgcattgg caatcgcata agcgatataa gcaagggcaa gccacatcaa
     5941 ctgatcattt tgagcaactg ctttgaacac atctttgatc ccagcttttt cattttgctg
     6001 acggatcgca gtatcgactt cttttgtgcc caaggcagtg ataatcgcag taccgcctga
     6061 aataacagca gcaatcacac cgaaccagaa ccagcctgaa gcgccttcaa tatgtttatg
     6121 agtaacaaga taggtaaaga aagtaacgat agggacaacg actagagtag taccatttgc
     6181 acctagagaa gagccgaaac gagcaaacgt agcaaatttt tcacgttcct ttgtttccgt
     6241 actcaaagct ggaatcattg accaaaaagc gatatcctta aatgaataaa aactatccaa
     6301 taagatgaaa acgattgcaa ataatatgat aaataaagtc gtattatgag tagctaagcc
     6361 aaagaaattg gtaaagattg ctaccaagag tacggaacta acaacgccgc cgataactaa
     6421 ccatggtttg aatttaccgt attttgtacg agtattatcg atgatgccac caatcaaagg
     6481 atcaaaaata atttcaacta agcggatacc tacaactaag cttgtaactg tagcaatcat
     6541 ttttgcattc gttgccttat ctgttcctgc gaacatctgg cttgtcacga ataccataaa
     6601 ataagtgctt aatgtaacat agaatgtgtc gtgtccaaaa gcgcctaaag cgtaggacac
     6661 acgttggatc attttgcttt tcataatctg tattcctctc ctgttcaata tataatacta
     6721 agtaaaccgg ttacaacgaa taacaaagat cttttaatga cttaaactta acaagaaatc
     6781 gcttcctttt taatatattt ctgtgacttt tatttaactt tttgttgcat tatactaaag
     6841 gagtaaggag ggatagacgt ggagcaatcg atttttttaa aaaaggaaca tcaacaagta
     6901 gaaaaagaat tgtattttga tttttgtggt ttctctaaaa cgatgccgtt tcattctttt
     6961 ggtcctgcta ttcgcaatga ttacatcctg catgtcgtga tggaaggcaa aggatcttat
     7021 catgtgaaaa atcaacaatt ccaattgaaa aaaggtgatc tgttcttgat tcgtccagga
     7081 gactcgacgt tttacttatc agatggagaa gatccgtgga tgtattgctg gctttcattt
     7141 ggtgggagtg ctgcagaaga aatcattcgg cagtcgcttt tcagagaaga ccaatacacg
     7201 atggtctctt ctgacataca aaaatatatc gacattattt tagaatgcat gaaagatacg
     7261 gaagaaacct tggaaaatga attacagtta acagcattaa cctaccgttt tttatcagtc
     7321 cttttaaaag atggcggaaa ggtcagcggt ggtgtacaaa aggttcattc ctctttagct
     7381 gttgaaacag tcaaatacat cgaggcacat tatgctgaaa aattgtctgt tgaggaaatc
     7441 gcccagcatt tagcggtcaa tcggagccat ttgtcgcgag tattcaaaaa tcatatgggt
     7501 accagtatca aggaatattt gatcggggta cggatcaatc gaggggcgtt tcttctttct
     7561 ctgacggatg aatccgtgga aagtattgcc tatcaagtag ggttcaatag tctagtcgta
     7621 tttagccgaa tgttcaaaaa gagtaccgga gaaacggcta cgaactatcg taaacgtatg
     7681 aaaaacgaaa attttaagaa tattgctttg gataccttga aaaaacagtt ggaaaaacaa
     7741 accgcagttt cttggacaac ctgattagtc tggttaaaat gacaagcatc ggcaaaagaa
     7801 acttgtggcg gttatgctac actgtaaagc gaagactaaa aaggaggaaa agggatgcgt
     7861 acacttatca tcattagcca tccaacgatc gaagaatctt taaatcagca atttttcaaa
     7921 gaagcttctg ctggtttacc agctacttgg catcatttgg aatcaagtta tccagacgga
     7981 aaaatagata tagagactga actacagctc ttggcccagc atgatcggat cattttccag
     8041 tttccgtttt actggtatag ttctcctgct catttaaaaa tttggcaaga taatgtcttg
     8101 gaacgagcag cacatgtatt aaaagggaaa gaactaggaa tcgtattgac aacaggtgtg
     8161 gcggaaaaag aataccaagc tggaggaaaa gaagaatata cgatttccga atttttgagg
     8221 ccgtatcagc gaatcgcaaa taaattccat atgacctatc ttccgccatt cgttttagca
     8281 caatttatgt atttatccca ggaaaaacgt tgggagaagc taattgctta tcagcagtat
     8341 ctctcattgg aaggcaaacc atcgctgact cagcggattg actggtttat tcaaagagta
     8401 caggaaaatc agaaaatgca ggaagaagaa tctgaaaaac aagcatatat cgtagaagca
     8461 ctgactgagg caaaagagca gatcgaagac ttgaccttta cactgcaaga aatgaaagga
     8521 acttcattat gacaaatgat tggctgatcc aacaattaga tgaattaagc gaaaaatcag
     8581 aatatcaaga ccgtgcgctc ttatatgaaa taaagaaact gatggctgag atagacgaac
     8641 gaacaatgca gctgcaagga gaaatcgacg gacaatcttg gaatcatctc aactggtgaa
     8701 attttcttat aaataacaaa gataaaaatg tgcacagcga caattatttg ctacaataag
     8761 aatatgaagc gtttgataac gctattatac ataaaaattg gtggtgaaaa aaatgtatga
     8821 tgaaaatgag tggggagaaa atgttcggat gacccgaaga agacagcaaa aacaggcagc
     8881 tcgtaagcgg atgatcatga ttggggcagc agttgccgtg tttttgatca tagcaggagg
     8941 agttgcgggt ctatattttc atggaaaaaa ttcgtcagaa gcgaaaagta cgaccataac
     9001 ggaaacaacg acaaagaaaa cagagacgaa acaaacaagt gagtcatcaa ctaaaacaaa
     9061 agagacacaa acttctgaag aaaaaacagc aaatggtttg ccagagcaac ttcaagcaat
     9121 cgtaaatgat tattcgaaaa agatcgaaga aaagacgcct gcattgattg aagaatacca
     9181 gacagaaatt cagggaaatc aagagggaat agctggttta tcagcagttg ctaaccaaaa
     9241 agcacgtgag cttcaagcaa tctccgacga agggatcaga aaattacgtg cagcgtatca
     9301 ggcagcagaa aataaagacg gtgtagactt agatactttg atcaatcaat tatcggctaa
     9361 ttatacgaat catgtcgcta agatttccga tatttatttg cagactagcg cctctcttca
     9421 agcagagtca acaagcacac aagacacaac atcttctgat tctgagacag cagagtcggt
     9481 agaagcttct gaaatgcaag ctcgaacaac acaagacaca acagattcct ctgaaactaa
     9541 taccaacagc gcgacttcac aggctgcgac aaccgtagtt ttggaaggag aaggtccaaa
     9601 tcaaatagcc gaacgaactg gcgtaccagt agaaacgatc ttgtcgctga atgggatgag
     9661 catggagaat tatttcctga ctcccggtga gacgctaaaa ttgaattgat aaaagcaata
     9721 aaaaagaacg aagcttccac taaggtgaag cttcgttctt tttttatttt ccggttcttt
     9781 tttcgcgtac aaagtaatgg atcgtcatgt aaagcaagaa aacgagtcca ataatcaatg
     9841 agattctcgt ttcaggattg ataaacatga aaatcaatac gatagctaaa aaagcaagtg
     9901 tcacataatt cgtataagga gatagtggca ttttaaaagg atgatcatgc attttatctg
     9961 cgtgcttctt tttgaagcga atctcgctga tcaaaatcac tacccaagga accataccag
    10021 gcaaaatact tgagctgtat acgaaaacga aaatattttc tgactggttg atgaacattg
    10081 gtagaagata atttaagatc agaccaatta agattccacc tgagattgct acgacaggat
    10141 aaaaaggcgc accgtgacga gatagtttca gaaatttttt agacatcttt ccatttatgg
    10201 caagtgtata gaccatacga cttgcgctga aaatccctga attgcaacct gataatgccg
    10261 ctgtaatcac gacaaaatta atcagtcctg cagcaaatgt aatgccgact ttagaaaaag
    10321 tttgtacaaa aggtgaacca atctcactca attgattcca cggatagata ctcacaatga
    10381 taaaaatagc accaatataa aaaatcaaga ttcgaccgat agtggactgg acagcttcaa
    10441 tgatcgtctt tttaggattc tctgcttcac cagcagtcat tccgatcagt tcgattcctt
    10501 gataggaagc aacaacgatc gataatgcaa agaaaaatcc tttgacgcct ccagtgaaga
    10561 atccaccatt tttccaaaga tttgaaatcc ctactgcctg accatgatta ccaaatccaa
    10621 ataagattac cccaagacct gcaatgatca tcaaaatgat cgttatgact ttgatgatcg
    10681 aaaaccaaaa ttctaattcg ccaaacgcct tgacagaaat aagatttgcc agcataagaa
    10741 acaagacgac aatgattccg ggaataattg ccggcaaatc aggccaccaa taattcatat
    10801 aagatcctac agcaatcact tcacttattc ctacgacaat atattgaaaa atattactcc
    10861 aagcggtcaa gtagccagcc acaggatgga tgtactcgct cgcgtaattt gcaaaagaac
    10921 cagtcgaagg atcaacgtaa agcatttcgc ctaaagcacg cataatcaaa tacaaaaaga
    10981 atcctgcaat cgcataggct cccatcactg agggccctgt ccaacgtatg gttgaggagg
    11041 cacccataaa cagaccgaca ccgatcgttc cacctagtgc gatcatttgg atatgacggg
    11101 cactaagact tcgagttaac ttttcttctt ccatacaaaa actcctttcg ttgttgagtc
    11161 aacaagaaaa aataatcaaa cgtttcaaca catgtttttc attattaggt tagccttatt
    11221 gaactcttga tgtgattcta cagaaaattt tcataaaatg cgaggaaaat tcgaaaaaaa
    11281 ctttttcatc attctacttg aaaatgcttt ccattttagt taaactatat ttaaataaaa
    11341 agttaggtaa acctaaaaag gagtgtaaga tttggaacgt acggccattg taattcaaga
    11401 cctttcagcc gcttatcaag ggaaaactgt tttgaaaact atcaacttga cgataaatcc
    11461 acaaaaaatt accggtatta tcggaccaaa cggtgcagga aaatcaacat ttatgaaatc
    11521 tttgctagag ttgataccag ctactactgg taaagtcacc ttttctggac agtcggtaaa
    11581 ctcagtccgt aaaaaaatag cctacgtgga acagcgaagt gaattggatc tttcctttcc
    11641 aattgatgta ttaggcgttg tacttttagg aacatatcca tctttacgaa ttggacaaag
    11701 acctgggaaa aaagaaaaag aacgtgcaag acaagctttg aaaaaagtag ggatggaaga
    11761 atatgccaaa agacagatca gcgaactatc gggtggacag cttcagagag tttttattgc
    11821 aagagctcta gcccaaggag cagaatggat ctttttagat gaaccattcg tagggattga
    11881 tgcgttaagt gaacgaaaga tctttgacat cttgcaggaa ttgaagaatt caggaaaaac
    11941 gattttgatc gtccatcatg atcttcataa agtagaagaa tatttcgatg aggttattct
    12001 tttaaataaa cagctgatcg cttccggtcc agtacaagaa gtctttacat cgaagaacct
    12061 tcaattggcc tatggtgaga tcatcagaca tttagtaaaa ggaggagaga aaaaatgatc
    12121 caatccttta ttgatggatt aatgaattat caattcctgc aatacgcttt ggtcacttcc
    12181 atgcttgtag gacttgcttc tggagtcatc ggttctttta ttattttacg agggatgtct
    12241 ttgatgggag acgctatctc tcacgcagtt cttccaggtg tagccatttc ttatatgttt
    12301 ggttttagtt acatctttgg agccactgct tttgggatgc taacagcagc agtgattggt
    12361 ttcgtgactc agcggagccg attgaaaaat gatacagcga ttggaattgt ctttagctcc
    12421 ttttttgcat tagggattat cttgatttca tatgcccaga gtgcgacaga tttgtatcat
    12481 attttatttg ggaatgtctt agctgttagg gaaagcgatt tgttgctgac agcactcgtt
    12541 agtggaatcg tcttgatatt tgtctttttc ttttataaag aattgaagat cacatcattc
    12601 gatccgacaa tggcaaaagc ttatgggctg aacacatcgc tgatccatta tcttttgatg
    12661 ttctttttga cattagtggc tgtagtcagt ttacagacag taggaacaat cttggtgatt
    12721 gccatgttga tcacaccagc cgccacggct tacttgctaa cgaaccattt actgaaaatg
    12781 atcattacag ctgcaggaat cggtatgcta agtgcagttg tcggtgtgtt tttcagttat
    12841 agttacaatt ggccatcagg agctacgatc gtgttagcat gtaccgcatt ttttatcctt
    12901 gcttttttat tttctccaac aaaaggaatt ttatttcaga aaggaagcag atagatgaaa
    12961 acaaaaaaat cactcttttt aatcttggca gttagtttct tggtattagc cggttgcgga
    13021 aagcaggctt ctgaccaagc ggatgaagga agtaaagaaa agttgtcagt cgtggctacc
    13081 aattcgatct tggcggacat ggcaaaagag gtcggaacag atcaaataga tatccacagt
    13141 atcgtaccag tcggaacaga tccgcatgaa tatgaagtac taccagaaga catcaaaaag
    13201 gcaagcgatg cagatgttat tttatacaac ggtttgaatc ttgaaacagg taacagctgg
    13261 ttcgataact tgatggaaac ggctaaaaaa gaagaaggaa aagattattt tgcagttagc
    13321 aaaaatgtag aacctcttta tttaactagc ggtgaagaac atacaaaagc agatccccat
    13381 gcttggctag acctatctaa cggaataaaa tatgtggagg aaatcgcacg tatattctct
    13441 gaaaaagatg cagaaaatgc gacactctat aaaaaaaatg cagaagcata tgtggaaaaa
    13501 ctaaaagaat tagatacaca agcgaaggaa agttttgctt ctatcgaaga gaacaaaaaa
    13561 ttattagtaa caagtgaagg ggcattcaag tatttttcac gagcatatga tttgccagca
    13621 gcttatatat gggagatcaa tacagaaagt caaggtacgc ctgatcaaat gaaagcgatc
    13681 attgatcaga taagagcaaa agaagtaccg gttttattcg tggaaaccag tgtagactca
    13741 agaagcatgg aacgggtagc aaaagaaacg ggtttgaaaa tctatgataa actgttcact
    13801 gattccatag caaaagaagg agaacaagga gattcttact atcagatgat gaaatggaat
    13861 attgaaacga tccatgaagg tttgtcacaa acaaaagaaa gctgaaaagt gcaaggtcta
    13921 gcttgaggag cagaccttgc attttttata agagatatga aaaaaaatta tgctgttttt
    13981 cgtcgtacag ataccttttt tgaagaaatt ccgttatagt tagagtaagg aaggaaggtg
    14041 tggctatgaa ttttacacgt aaagataaat atacgattaa agaagaagtc tttcgattga
    14101 tcagccagca ggaaaatacc gacaaggatc aagaccttca atttcttgaa gcagaattag
    14161 ctaaattatt catagcaaat caaaatgaga caacagaacc agatgaagag ctgtacatag
    14221 gcaaatggtt gtttgatgaa tttcagcctt tagatgaaaa taccggtatc ggttattttg
    14281 tgttcctttc tccagtcggc ttcacacctg gcgtattagt taaacaaaac gacgaaataa
    14341 ccgtcaaagc atggcctgca ttattttcag tcatcaaagc agaaggagta atcaaaaaga
    14401 tccagtcggc ctattataaa agtcaattta ttgccaacag caaattaatg aatatgtttt
    14461 ataatcgtct agtagaaatt gctaggcctg ggaaaatccc gcaaacattc acgtacacac
    14521 agcaaaaaaa tctctatgaa gaagtattgt attcccgcga tctgtctgag ttttcgccat
    14581 gggaagaggt aaggctccat gaactgttaa gtacaaaacc agtttcattg aattttttta
    14641 atgcattaga taacaaaaga aaattaattt caacaaatta ttgggaagta tttgctgcaa
    14701 gaaaaaaatg gatggaagaa aagaagattg ccgatcagca gatccagttt gtccagctga
    14761 aaaaagaaaa actatattat gggttataca gccgttaaca gcaagcgagg aagaccatga
    14821 cattaaaaga agaaatcata caagaaagca aacgattagg aattgacaaa atcgggttca
    14881 ccacggcgga accttttgat tcattaaaag aatcgttgga agaacaaaaa gcagctggcc
    14941 atacttctgg ctttgaacat ccaaatatcg atgagcgtct ttatccagaa atgacatttg
    15001 atcagccgaa atcgatcatt tccattgcac ttgcgtatcc tactaggatc catgaagaag
    15061 tgcctaggga tgaaaaacgc gggcagtttg ctcgtgcttc ttgggggatc gattaccatg
    15121 atatactcag agaccgtttg aaccgattga tcgaattcat ccaaacaaga gcagaaaaat
    15181 ggcaaaaaga agaggaatgg cgtctagctc cgcaagtaga tactggagaa ctgatcgatg
    15241 tcgctgtagc acagcgagct ggtttaggat ttattggacg aaacggattg ttgatcactg
    15301 aagagttcgg ttcatttgtc tatcttggtg agatcgttac taatattgta tttgagcctg
    15361 ataaaccagg agaatttggt tgcggtgact gtatgcgctg cgtgactgct tgtccgacaa
    15421 aagcattgct tggtgacgga agaatgaatg cccagcgatg tttgtcttat caaactcaga
    15481 caaaagggat gatgccggaa gaatatcgta aaaaaatgcg aaatgtcatt tatggatgtg
    15541 atatctgcca gttagtctgc ccttacaatc aaggaaaaga ttttcatttt catgaagaga
    15601 tggaaccaaa agtagacgaa atatatccaa aattaaagcc aatgctttcg atgtctaata
    15661 aagacttcaa acagcaattt gggcatttag ctggttcatg gcgtgggaag aaacctttgc
    15721 agagaaacgc attgattgct ttagctaatc taggtgatcg aacggcattg cctgagattt
    15781 cagaatgttt aacagatgtc cgccctgtca tcagaggaac agcagcttgg gctattggac
    15841 gtctaggaac aaaagaaccg gaaaaatggc ttgatgtatt agatgaaata ttagctaaag
    15901 aaacagaaga agtcgttata aacgaattgg aacatgccca gaaattattg cggagaaagt
    15961 taaaataaaa aaatagttaa cattattcaa agtttttgtc cagtaattgt tgtaacaatt
    16021 actggttttt ttgtattttt tacatttttt taagagaatt tgataaaaat caaaaatttt
    16081 tttgcttttt tttatggatt attgcagtga atgttacaga atctgcgttt ttcattcaaa
//
LOCUS       DACBYO010000066        16043 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.066, whole genome shotgun sequence.
ACCESSION   DACBYO010000066 DACBYO010000000
VERSION     DACBYO010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16043
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.066"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            27..142
                     /gene="rrf"
                     /locus_tag="IVD26_002035"
     rRNA            27..142
                     /gene="rrf"
                     /locus_tag="IVD26_002035"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(195..665)
                     /locus_tag="IVD26_002036"
     CDS             complement(195..665)
                     /locus_tag="IVD26_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAP6079974.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(824..1282)
                     /locus_tag="IVD26_002037"
     CDS             complement(824..1282)
                     /locus_tag="IVD26_002037"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAP6079975.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1453..2598)
                     /locus_tag="IVD26_002038"
     CDS             complement(1453..2598)
                     /locus_tag="IVD26_002038"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAP6079976.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2611..3528)
                     /locus_tag="IVD26_002039"
     CDS             complement(2611..3528)
                     /locus_tag="IVD26_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAP6079977.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3956..4519
                     /gene="efp"
                     /locus_tag="IVD26_002040"
     CDS             3956..4519
                     /gene="efp"
                     /locus_tag="IVD26_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAP6079978.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            5005..6264
                     /gene="lysA"
                     /locus_tag="IVD26_002041"
     CDS             5005..6264
                     /gene="lysA"
                     /locus_tag="IVD26_002041"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAP6079979.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6251..7051
                     /gene="dapF"
                     /locus_tag="IVD26_002042"
     CDS             6251..7051
                     /gene="dapF"
                     /locus_tag="IVD26_002042"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAP6079980.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            7054..7935
                     /locus_tag="IVD26_002043"
     CDS             7054..7935
                     /locus_tag="IVD26_002043"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAP6079981.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7932..8648
                     /locus_tag="IVD26_002044"
     CDS             7932..8648
                     /locus_tag="IVD26_002044"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAP6079982.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8654..9349
                     /gene="dapD"
                     /locus_tag="IVD26_002045"
     CDS             8654..9349
                     /gene="dapD"
                     /locus_tag="IVD26_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAP6079983.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9365..10366
                     /locus_tag="IVD26_002046"
     CDS             9365..10366
                     /locus_tag="IVD26_002046"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAP6079984.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10363..11724
                     /locus_tag="IVD26_002047"
     CDS             10363..11724
                     /locus_tag="IVD26_002047"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAP6079985.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11684..12835
                     /locus_tag="IVD26_002048"
     CDS             11684..12835
                     /locus_tag="IVD26_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAP6079986.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12810..13979
                     /locus_tag="IVD26_002049"
     CDS             12810..13979
                     /locus_tag="IVD26_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP6079987.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            14154..15533
                     /locus_tag="IVD26_002050"
     CDS             14154..15533
                     /locus_tag="IVD26_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP6079988.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15814..16043
                     /locus_tag="IVD26_002051"
                     /pseudo
     CDS             15814..16043
                     /locus_tag="IVD26_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5244 a         2835 c         3423 g         4541 t
ORIGIN      
        1 ttactcaata aaagataaca ccacagtgtg gtggcgatag cgagaaggat acacctgtaa
       61 ccatgccgaa cacagaagtt aagcttctta gcgccgattg tagtgagggg ttgccccttg
      121 tgagagtagg acgtcgccac gcaaaggcaa aaagatgaac tagaaatagt tcatcttttt
      181 ttatttttat taagttaaag aacggattca attgcagcgg tcattttcaa tggagaagtt
      241 tgtggtgcaa atcgttcgat tactttgcca tttctatcaa tcaaaaattt agtaaaattc
      301 cattttattg ctttagtgac agtaccagga gcttcatttt taagataagt aaaaagagga
      361 tctgtatttt ctccatttac gtcaatcaat tgatgcatag ggaaggtaac gccataagtg
      421 gttttacaag cttctgctgc ttcagtcgct gaatctagct cttgtttaaa ttgattggaa
      481 ggaaagccta agataaccag accttgtgtc tgataagctt ggtaaagttc ttctaattgt
      541 ttaaattgag gtgctagacc gcattttgtt gcagtgttaa caatgattat cggtttgcct
      601 gcatattttt tcaatgaata gacagtgccg tcttctaaag tagtttcaaa attataaata
      661 gacataaagt tttctccttt ctattttata taataaaaag agcgctaaac tgaaaactag
      721 ctatttgttt tcccgtttag aactcttttc agacaataaa tatttaataa aatacgaaga
      781 taagatagct atattgcttc tcatctttac gttcttttag aaactatgct tctacttcag
      841 accattcatc gcgttttgct aaaaattcac gagccaaagc ttgtgcacct tctagtgtat
      901 ggctggcagc ccagccacat tgtgtttcat tgcttgcagg tacttcagta gcttcaagaa
      961 catctttcat tgttgcttca agaacatcta aaatgtcttc gtagctttca tgattcaata
     1021 cagtcaagta aaagcctgtt tggcatccca ttggagacca gtctacgatg taatctgcgt
     1081 gattgcggat tagttcggca gtcaagtgct caagtgaatg tagacttggc atgtccatgt
     1141 gttctttatt tggttgttta aagcggacgt cgtatttaat gatgacatcg ccatgcgcac
     1201 ccgtttttcg atcagctaca cgtacataag gtgctttgac ttttgtatgg tcaagattaa
     1261 aactttcgac attcattctc atttgtaaga ctcctatctg tttgttcatt cgttttgatg
     1321 cttttcacta aagaattatt tagtgaaatt tacaaaaacg tctttctact tgattctaac
     1381 acttatcgtt tccaaggtgt agcaatctga aatatttttt agatttttct gctaagtcgt
     1441 ttattgggac ttctagttct tgattctgtc aaatgcctga gctaaatcgt ttatgagatc
     1501 ctgaccatac tcaattccta cagaaagacg gatcaagccg tcctttatgc cagcctcttc
     1561 tcgtttttct tttggaatag acgcatgagt catgacagaa ggaatttcca ctaaactttc
     1621 tacgccacct aaactttctg ctaaagtaaa tagttggagt gattcaacaa atggaatagc
     1681 agattcttca ttttttaaag taaaagaaat cattccgcta aagccgctca tctgctgctt
     1741 agcaactcca tggagttcat gatcgggtaa tcctggatag tagacctttt ctactgctgg
     1801 atgagaaaat agaaaatcag ctaccacaaa agcatttttt tgatgttcct ccatacgaac
     1861 acttagtgtc ttgattccgc gctgaagtaa ccagctatct tggggaccaa gtacggctcc
     1921 gatagcattt tggtaaaatc cgatctgatc ggctagatct ttatggttag aagtcactaa
     1981 accagctact acatcgctgt gtccgcctag atatttggta ccgctatgga caacgatatc
     2041 agaaccgaga tctaaaggtc tttgaaaata aggagtagca aatgtattgt cagcaataac
     2101 tatcaatcca tgttgatgag ccagagtggc acttttttct aaatcagtaa tctttagaag
     2161 cggattgcta ggtgtttcaa gataaagtgc ttttgtattg ggtttgatgg attgttctat
     2221 tttatcaaga ttactcgtat ctatgatcgt gtactcgaga ccatttttag taagaacttt
     2281 gtcaaataga cggaatgttc ctccatagac atcatctcct aataagatat gatcgccagc
     2341 ttgaaaaaga gaaaaaacgg catgaatccc agaaagacca gaagaaaaag cgaatcctcg
     2401 aacaccgcct tccaaatcag caatcagttc ttccaatgca aaacgagtag gattaccaga
     2461 tcttgaatat tcatattgtt taggctggcc gacgccatct tgccgataag tggatgtttg
     2521 ataaataggt acactgacag ctcctgttgt gggatcttca ctgatgcctc cgtggatcaa
     2581 ttttgtttga atgtgcatgt ttctttcctc ctataagtaa atgttttttg ataaatagcg
     2641 gtctgctgcg tctggaaaaa tcgtaacgac acgatgacca ggtggtaaac gacgaatttc
     2701 tcttaatgct gctgcaaaag ccgcaccact cgaacttcca actaatagtc cttgttctcg
     2761 tgctaactgc ctagtatagt taaacccttc tacatcagag attgtctcga tctgattgat
     2821 tgaaagggga gaaagaaacg gcggaatgaa ttctacaccg ataccctcaa tttcgtgagg
     2881 ggctggatca ccaccattta acacagagcc ctctggttct acaccgatta ttcgaatgtc
     2941 gggatatttt tctttcaaaa aggtagaagt tccagcaaag gttccaccac tcccaattcc
     3001 tgctacaaaa ctatggatat tttctttgat ttcatgaaag atttctggcc ctaacgtatg
     3061 atagtaagca gcaggattat ctttattttc aaattgaaga ggcagatagc tgtttgatat
     3121 ctcctctgca agttttttac ttttgctgat ggcaccgatg attccttgct cactaggaga
     3181 atggatgatc tttgctccca atgctttcat caattgttgt ttttctaagc taaacttctc
     3241 tggaacaaca aaaaccgttc ttaatttgta tgtgagtgcg gccagagcga tcccaattcc
     3301 tgtatttccg gcagttggtt cgatgatcgt cgttttttca ttgatttttc cttgggcaaa
     3361 tccttctttg atcaaataac tgcccaatct atctttgata cttcctccag gatttaaata
     3421 ttctagtttt gcataaatag cagaaccttt aggcatagaa tagtgctgat tgtcaaagcg
     3481 ataaagcggt gtggaaccaa tagcttctgt aattgtcgag ataatcatgt gggcctccta
     3541 aaaaaagata ataaaaaaag gagctgacta ttaaatcagc tccttgaaag acatagagaa
     3601 aaattgagta gataaaaaga taagttacct ggtactcatt ctatgaaggg caattaatag
     3661 acatgacaaa tagtatgctg cttttatgca ccatacaaca gcaacgattc aattgttttt
     3721 ggttgctgac tgtcatgtgt atccctccaa gtaaaatttt tattaacgat agcatgaaaa
     3781 aaaataaaag tcaaaggctt gaaagaaaaa aatatttcga tagcatcgtt tacccgtgtt
     3841 tatttttctg acaaataggc atgagacctt aaaagataga gaatactcta gttttctggc
     3901 cggttgtctg atacaataaa gttgattatg ataaagaaaa gaaggagcaa aaataatgat
     3961 ctcagcaagt gatttaagag ccggtatgac tttcgtacaa gacggcaaac tgattaaagt
     4021 tctggatgca agccaccata aacctggtaa aggaaataca gttatgcgta tgaaactgaa
     4081 agatgtccgt tcaggtgcaa catacgacac aacgttcaga ccagaagaaa aatttgaaaa
     4141 agcacatatc gacacaaaac ctgtacaata tttgtacacg atggatgata cagctttctt
     4201 catggatttg gaaacatatg agcaatatga aattcctgta gaaacagtag aagaagaaat
     4261 gaaatatatc ctagaaaaca tggaagtaaa aatccaattt ttcggtagcg aagtcatcgg
     4321 cgttcaatta ccaacaactg tcgtattacg tgttgtggaa acacaacctt ccatcaaagg
     4381 tgcaacagtc actggttcag gtaagccagc gacaatggaa actggcttag tagtcaatgt
     4441 tcctgacttc atcgaaacag atgaattgtt ggaaatcaat acagcagaag gttcttatgt
     4501 aaaacgtgcg tcaaaataat tcgctaacgg attgataaga atttgaaaac agagcttgac
     4561 ctcttgaaag gcagatcatc ggatctgcct ttcaagaggt tttttgtgga atcagcaaat
     4621 tgaaaaataa aaaagtattt gattttattt atattttgaa agatgaatgg caaaagctag
     4681 agaaagaaaa aactgcactt atttatgaag aaattgaaat gattcataaa attgaaaata
     4741 tccgaactat tccgaactat attgaagcga aaatattttt tcatcactaa atagtgttga
     4801 atttatgttt ttatgtataa atagcttcta atagttcggg tattttgttt ttataaccat
     4861 ttttattctt atttttaaaa aaatatttcg aaatatacta gacaattcag aaaattttgt
     4921 ttaatattat tccaataaaa ttcaaatctt tatcaaatga aattccaata aaaacggaaa
     4981 aaaagtgaaa agaggaatga aaaaatgaca gaattgataa ttggcggagt cacagcaagc
     5041 acattggcag aaaagtataa gacacctctg tatgtgtatg atgaagaaaa gatgagacaa
     5101 acgatgctgt cattcaagcg aggctttgta tcgaaacgtt ttgatacaaa agtgctttac
     5161 gcctctaaag cattccaaac gattgagatg ctgcatttag ttcgtgaata tggattcggg
     5221 ctagatgttg tcagtggtgg ggaaatctat accgctttgc aagctgattt tcctagagat
     5281 actatctact tccatggtaa caacaagacg ccagaggaac tgatctatgc acttgaaaat
     5341 gatttgttgc atattgttgc cgataatttg atggaagttg aattattagc agaattaagc
     5401 caacgctatt taaaaaaaat ctgtatcatg cttcggttga atgtcggagt agaagcacat
     5461 actcatgaat atatcgtcac tgcgcatatt gattcaaaat tcggcatgag ctatgaaagt
     5521 aaagagtgcc aacaagccct tcagttgata aaagaaagca gctatctaga gttagaagga
     5581 tttcatgctc atatcgggtc acaaattttt gatgttactg cttggttagc tgaaatcgac
     5641 aaattgacga attacttaac cgattttgac caacctcttt ccttgaatct tggcggaggg
     5701 tttgggattc gttatacaca aaatgatcag ccgatcccag tcgaagaggc actaaaaaaa
     5761 ctgattgaat atacggaaga agctttggaa aaacgaaaac tgaccattcg tcaattactg
     5821 atcgaaccgg gtagaagtat tgttggagaa gctggtacaa cactatacac gattggtttc
     5881 atcaaaaaga caccacataa aaaatattac tttgtagatg gcgggatgac agataatatc
     5941 cgtccagctc tgtatcaggc agaatacgat tgtgatttag cagcaaaact gtcggaagaa
     6001 aaaacagaga aagtgacgat tgcaggaaaa atgtgtgaat caggcgatgt ggtaattaaa
     6061 gaagcttatt tgccgaaagc agaatcgggt gatcttttag ctgtttattc cacgggagct
     6121 tatggatact cgatgagcag caactacaat cgagcgacac gaccagcagt tgtttttgtc
     6181 aataatggcc aatcaagact gattgttcgc agacaagcat tttctgatct actaaggggg
     6241 gaagtttcct atgatccttc ataaatataa tggctgcgga aatgatttta tcttattaga
     6301 ttacgcagaa gacacagatt atagtcaatt agccgcttct ttatgcacaa aagaaaaata
     6361 tgatatagac ggattgatcg ccgtaaaaat cgatccgttg gaaatgatct attacaacaa
     6421 agatggcagc cgcgcgccga tgtgcggaaa tggcattcgc tgttttgctc gatacgtaaa
     6481 tgatcagaac atgatgaatg aacaggaatt caacgtagag acattagcag gcacaagaaa
     6541 aattacggtg ttggatccct caccttttta ttgcagcgta gatatgggag tgccagatga
     6601 ttctccggaa aaaatcaaag ctaatcaaac ttatccaata aaaaaccagg aaatagagat
     6661 caatggtgaa aaagtaacga tcactagttt atttttagga acgattcata ccgttgtttt
     6721 tgttgaaaat gcgcgtgagg aagtctggag aaaaagaggt gaactgatct gtcatcatcc
     6781 tttgttcaaa gaaaaaacca atgtcaactt tgtagaagta gtcaatgaac aagaattgat
     6841 cgtccgtacc tatgaaagag gagtaggttg gacacttgct tgcggtacag gttgctgtgc
     6901 ctcttatgtg gttgctaagg aaactgggaa aatttcagca gatcaggtag ttgttcactt
     6961 ggaacaagga gacttgatga tctctggtga ggatgcgata caaatggctg gcccagcagt
     7021 tcatgaatgg acaagaatat tggaggaatg aagatgataa aaggttcgat cgtggcgctg
     7081 atcacgccga tgaatgaaga gggatcagta gattatgctg gtttggaaaa attgatccaa
     7141 ttccatttag atgaacaaac agatggatta ttagttttag gtacaacagg agaatcttct
     7201 acgctcacac aatctgagga ggagcagatc cttcaactga cagtaaagaa agtggctggc
     7261 cgtgtgccgg tgattgcagg agctggaacg aataatacga aagaaacgat tgaaaaagcg
     7321 aagcattttg cttctttggg ggcagacgca cttttggtca tcacccctta ctacaacaaa
     7381 acaagtgatg caggactagc tgctcatttt acagcaattg cagaagcctc accgattccg
     7441 cttattttgt ataatgttcc ttctagaaca ggcatgtcga ttccaatcca tgtattagta
     7501 aatttagcag aacatcctaa tatcattggt ttgaaagaag cctcaggaga tatggcttat
     7561 gtgatggatg ccgctcggtt gattggagaa gaattcttcc tttacagtgg aaatgatgat
     7621 ttgatcctac cagtaatgag tgtaggagga agcggtgtaa taagtgtatg ggcgaatatc
     7681 caacctaaaa tagtccatga attagtaaaa gatacgcagg acggaagatg gcagcaagca
     7741 aaagaaaagc aattaaatgc acttgaactg atccatgcct tgttcagtga gaccaatcct
     7801 attcctgtca aagcagccat gtcattatta gacttacctt ccggacctct acgcctgcct
     7861 ttagtttctc tttcaaaaga gaaaaagaaa caattagctc agcttttgtt aaaagaaagg
     7921 acggttgaaa aatgaaaatc ggactgattg gcagtggaca gatgggaaat agagtcgaag
     7981 aagttgcaca agaaagagga gatacggtcc ttcttttacg gacggcacct aaagaagcaa
     8041 ctacgcttgc ttttacggaa ctgccagaac tgcttattga tttttctcat ccagataatt
     8101 tagagaaaat cctttcgtat agcttatcat atcaacttcc gttagtcatt ggcacgacag
     8161 gttatacaca atcacagttc caagaaataa aagaacatgc caaacatgta cctgtgatgt
     8221 atagtgctaa tttttcgttc ggcatcatgg tgatgaatca actaatcaag caagcagctg
     8281 caatgttgca aggctggcag atcgaactga ttgaaaaaca tcatagtcgt aaaaaagatg
     8341 caccatctgg tactgcaaat atgctgcttc aaacaatcca agaagtgcaa aagctgcagc
     8401 ccgtatacaa ctggcaaggg aaaaaaagag aagaaaacca aattggtgta cacagtattc
     8461 gtgcaggttc tttacctggt gaacatgatg tattgtttgc tgctactgat gaaatattta
     8521 cgatcaaaca tgaatctttt tctaatcgaa tctttgctgc aggcgcagta gaagcagcgg
     8581 actggttgaa agatcagtca ccaggttatt acaaattaga agatttatta atggacaaag
     8641 gggtgtaaaa aacgtggaag ctcaagaaat catccgctac attcaaacgg catctaaaaa
     8701 gacgcctgtg aaagtctatc tgaatgtaac cgagccaatc gaatttaaag aaagtaaagt
     8761 ttttggtgaa ggaagcagct tcgttgtttt tggtgactat gagacgattg ctccggtttt
     8821 agaagctgaa tcagaaaaaa tcattgaaat cgaaatcgaa actgctgcaa gatacagcgc
     8881 agttcctttg ctagatatta aaaaaattaa tgctcgtatc gaaccaggtg ctattatcag
     8941 agatcaagtg tcaatcggca acaatgccgt gatcatgatg ggagcgatta tcaatattgg
     9001 tgcagtaatc ggtgaaaaca cgatgattga tatgggtgct gtcttaggtg gacgagcgac
     9061 agtgggcaaa aactgccata ttggtgcagg agctgtctta gcaggtgtga tcgaaccagc
     9121 atcggccaaa ccggttatcg tagaagacgg cgtactggta ggtgcgaatg cagtgattgt
     9181 tgaaggtgtc catatcggaa aagatgcagt cgtggcagca ggagcagtgg ttttagaaga
     9241 tgtggcagca gaaactgttg tcggtggaat acctgcacgt gtattaaaaa taagtgatga
     9301 tcagacaaaa gaaaatacag cattgattgc tgcgttacgc gaattataga ggagatggag
     9361 aaaaatgcgc gaaatagata cctgtattgt gggggcaacc ggattagtcg gccaaacgat
     9421 gctcaaagtg ttagaagaat atgattttcc agtaggacga ttgaaattat tagcttcaaa
     9481 acgttcagcc ggtaaagttt gtgtattcaa gaaaaagaaa cacactgtac aggaattgac
     9541 agaaacttca tttgaaggat atgatttagc gctattttct gcaggtgctt ctgtatccaa
     9601 agagtttgcg ccaatcgcac gaagtcaggg actatttgtc atagataatt cctcagcatg
     9661 gcgggaagat tcggatattc cattaatcgt tccagaggtc aatctggaag actatacatt
     9721 gaatcggctg attgcaaatc caaattgttc aaccattcaa gcggtacttc cgcttaaagc
     9781 tttacaagaa gcctttggta tccagcgagt caattattcg acctatcaag cagtttctgg
     9841 ttccgggcaa aaaggcattg aagatcttca tcgtacgcaa aatgacgagg aaccagtttt
     9901 gtatccttat aatattagcc aaacggtgat tccggaaatc gatcagcctt tggaaaatgg
     9961 gtatacaaaa gaagaacaga aaatgataaa tgagacccgt aagattctgc atcagcctgc
    10021 tttgccagta tcagcaacct gcgtacgtgt gccaatcgaa aatggacatg gagtctctgt
    10081 ggcagttcaa ctgcaaaaag agtttacgac ggaagaaatt agagagtgtc tcagccagtt
    10141 tccagggatt caattagaag atgatctagc agcacataaa tatccgacga gcattcttgc
    10201 tagaggaaca gatatggttt atgttgggag gatcagaaaa gacacttctt tagagaacgg
    10261 attgttgttc tatacgactg ccgataacat acgcaaagga gccgctgcga atgccgtaca
    10321 gattgctgca gctttaatgc agaaaatagc ggaggtggca agatgagtaa tacgctgaaa
    10381 gtagcgaaat tcggcggaac atcgatgtct catgaagagc aattcaaaaa agtccgtaca
    10441 attgttcttt cagatcccaa tcgccaagtg atcgttgttt ctgctttagg caaacgtacg
    10501 tcagatgatg acaaagtaac agacttactt tatttgattt atgcttacct tcagcatcat
    10561 gttgattgga cacccctttg gaaaaggatt tgtgatcgtt tcattcaagt aagagatgtt
    10621 cttgccctgc agttacctat tgaagatgaa ctagcacgca tacagaaaca actggaagac
    10681 gaaaagataa ctgaagatta tttagtaagt agaggtgaat atctgactgc tcaactgatg
    10741 gctgagtatc ttggttacca gtttattgac gcaaaagacc tgattttctt tgactatgat
    10801 gggaaaatcg atcaggaaaa aacagcacag gaaatcacaa aagcatttaa aagatatccg
    10861 aaaatggttg ttccagggtt ttacggggcg aaccctgcag gaaaagaaaa attattgggc
    10921 cgtgggggaa gcgacattac cggcgcgata ctggcgaaga tgttgcaagc ggaaagttat
    10981 gagaattgga cggatgtttc aggaatcatg atggctgatc cgcgaatcat cgatcatcct
    11041 aaaatcatcg aggaaatctc ttttagagaa ctgagagaga tggcttatat gggggctaac
    11101 gttcttcatg aagcagctgt tttcccagtt caagaggctg atatccccat ccaaataaaa
    11161 aataccaatg atcctttcgc tcaagggaca aaaatatcga atcacgaaat agaaaaggaa
    11221 aatggactga caggaatagc tggacgcaag gattttcttt ccatcacttt attcaaacgt
    11281 catatgtccg atgaaatcgg gtttatctgg aaagcaatga gcatttttgc taaacatgag
    11341 atatcaatcg aacatattcc ttcagggatc gacaatatcg gagtgatcgt ctcagcagaa
    11401 gcgattgccg ataagttatt tctcatcacg aaagaattaa aagaaacact tggcgtggaa
    11461 gaaatcgtcg tgatcgaaga cttagctttg atctctgtcg ttgggggtcc gcataaagaa
    11521 ttgattggat tatctgggaa agtgttatcg atattgaaca aattagaaat tcgcacatcg
    11581 atcttatcac aaggagcaca ggagttgaat ctgatcatcg gtgtaccgaa taatcaatat
    11641 gaaacagtag tgaagggtat ctatgaaggg atggtgaata cggatgctga aagaatatcg
    11701 aatggcactc catcaaattc ctgaaatcgg gtttcatgaa ttcaagacaa aaaaatattt
    11761 atatgaacaa gtaaaaaaca gcgaggccgt tatccatgaa atcggcgaaa caggactact
    11821 cctttatttt gataatcagc aagaagaaac gattgctttt cgaacagata tcgatgcact
    11881 gccagtcaaa gaagaaacga atctctcttt tgcttctaag catgaaggtt atatgcatgc
    11941 atgtggtcat gacggacata tggcgatgct tttagggttg actgacttta taactaaaca
    12001 cattgaggat cttatttata atgtagtact gatctatcag ccatcagaag aaatttccgg
    12061 tggcgcacaa agcgttattc agtcaggatt gttggataaa tatgaagtac aagcaatatt
    12121 tggctttcat ctatggcctg gactagctaa gggagaagtt ttctctcgac caggaccttt
    12181 gatggcacaa agcagtgaaa cagacattat cattaaaggc cagtctgcac atattgcttc
    12241 tagtgaaaaa ggaatcgata gtctggaggc agctgtacga tttttgaaga atgtttatga
    12301 ttttgaccgg caattaccgg cagagtggaa tcatctaatg aaatttggcc aaatccaagg
    12361 tggaacgatc cgaaatgttt tagctggaga agttattgta tccggaagta tccgttctta
    12421 cagttcagat atgcaaaatt atttgaagag gggattagac catttagcag aacagtttca
    12481 ctctacagct actatttctt ttcgctataa tgacggctat ccagctgtaa tcaaccatag
    12541 aggcttatat gcagcactgt tagattcaaa caaactacat gaattagatg ctccagttct
    12601 tcaagccgaa gattttggca tatatacgca acaatatcca tgtgtatttt tctttttagg
    12661 tgtcggtgat acccctgctt tacatgatcc gacgttcgat tttgatatgg atgttttaga
    12721 aaatggtgta gaatggtaca aaacgattct ttttacagaa aatcttcttg taaaaatcga
    12781 tagcagttca aaagaggagc gagtaaataa tgatgaattt atccaatcga tttagtccta
    12841 ggctttctag aatagaagta tcaaaaatac gacaattcga tcagcaaata tcgtcgatac
    12901 cagatgtgat caaactcacc ctgggagaac cggattttcc aactcctgaa catgtcaagc
    12961 aagcaggaat agcagcgatt gaagaagact tttctcacta taccggaatg agaggattag
    13021 aggaactgcg ggaagcggct tgtatatttc agcaacagcg ttatggatta acttatgatc
    13081 cgcaaacgga agttttgacg acagttggtg caacggaagc gattgcctct gcgttgttat
    13141 ctgttttgga agaaggagac aaggttctta ttccagcgcc tgcttattca ggatatcagc
    13201 cattagtgga actagctggt gctgaattga tcccgataga tacttctgac acagggtttg
    13261 tctgtcagcc ggaacaattt gaacgagcat ttgaacaata tggatcagct gtcaaagcag
    13321 tcattttaaa ctatcctaac aatcctactg ggacgacatt gtctgcaaaa caattgaaag
    13381 caatcgctga ggttttaaaa aaatatccgg tatttgttat aagtgatgaa gtatatgctg
    13441 aattgactta tagtggaacg catatgtcca tagctactta tcttccagaa caaacaatcg
    13501 tgataagcgg gttatccaag tcacatgcga tgactggttg gcgagtgggc tttatttttg
    13561 ctcaaaaagc ccttattgac gaactaatta aagtccatca atatctggtg actgccgcta
    13621 caacgatgtc gcaaaaagct gcggctgaag cgctaataaa tggggtgaaa gatagcgaga
    13681 atatgaaaga gcaatatcaa acacgaagag actatctggt ccagcaattg gcgcctttag
    13741 gatttgaagt gacccagcca aacggtgcat tttacttgtt ttgcaaactc ccagctgcca
    13801 ttcaaactga ctcttggcag ttttgtgtag aattagcgga acaggcaaaa gttgcgtgta
    13861 tcccaggaat tgcatttggc ccagaaggag aaggttatat ccggatttct tatgctagca
    13921 gcatggaaaa attacatgag gcctgcaaac ggatcaaaga ctttttaaca gaacagtgat
    13981 tcatagattt tatcaaaaaa acaatcgtta attttgcggt atattctgca aggagacgat
    14041 tgttttttaa atttagttca aatgaacgcg tttcttttga ttcataacta atgtaatgtt
    14101 aagtttaaat tgtttagaat gattttaaaa gaatattcaa ggaggtttca tcaatggaaa
    14161 aaatcaaagt tgtcattgta ggtgcatctc atggagggca tcaatcgatc ttggaactat
    14221 tgacacgata cggtgaaaat gtagatatca cgctatttga agcaggagac tatatttcct
    14281 tcatgtcatg tggtatggag ctgtatttag aagacaaggt aacagatgta aatgatgtac
    14341 gtaatttcag accagaaaac tttccgcaat ccaatgttca tattttaaat aatcacgaag
    14401 taaaaacgat cgatgccgat aaaaaaacag taacggttac tagcgcatca gataacgaaa
    14461 caaaagaata tccttatgac aaattgattt tgagttctgg tgtcaaacca aacaatctgc
    14521 cagtaccagg agcagatcta gaaaatgtct acttgatgcg tggatacaat tgggcaacca
    14581 aaatcaaaga aaaattaaat gatccggcta ttaaaaaaat cgctgtcgta ggtgcgggtt
    14641 acattgggat cgaagcagca gaagcaagcc gaaaagctgg gaaagaagtc gtattgcttg
    14701 atgtgatcga tagaccttta ggcacttatt tagatgctga gatgacagat attttagaac
    14761 aacacctaaa tgaaaacggt attgaagttt tgacaaatgc aaaaatcgaa gcttttactg
    14821 gtaacggaaa agttgaggca atcaaaacaa gtgaaaaaga aatcccagca gatctagtca
    14881 ttcaagctgc cggtgtgaag gcaaatacag aatggttaaa agggatcgtc gacttagatg
    14941 aacgtggctg gatccaaaca aatgaatact tgcaaacgaa tcttccagat gtgtatgcag
    15001 taggagatgc tacacttgct tattctatcc cagcacgcaa aaaaatgccg atcgctttag
    15061 cgactgttgc acgtagagaa gcacgttatg tagtaaaaca tctttttgaa gaagtaccaa
    15121 acaaaccgtt cggcggagtc gtaggttcct ctgcattaag tgtctttgac tatcattttg
    15181 cagcaagcgg attgaatagc tttacagcag caaaagcagg agtagatgta cgagtgtctt
    15241 attatgaaga tacgttacga ccaaaatatg taccagaaga acaaggaaat ccaaaagtgt
    15301 ccatccaatt attctcggat ccaatgaccc atcaattgct aggaggagca gtattatcta
    15361 cctatgatgt tacaggtcaa ggaaatgtat tggcactagc gatccaaaac aaactgactt
    15421 tagaagaact agcagaagct gacttcttct tccagccagg ctttgaccga caatggagca
    15481 tgttgaatct agccgctcaa caagcgttag gagaagaacc atttgtagaa taagaaaacg
    15541 aaatatttga aaagaggttg tgaaaaagct gccttgcatc aagtaataag aacagccaag
    15601 taaaaacagc ttcttatgtt tttaacttgg ctggacttat taccgcagat gcaagctttt
    15661 gaacaccgtt tattttcaaa aaagggactg tgacacgatt tgtgtaccga cccccaaaag
    15721 ttagaccaaa aaatctaact tttggaggtc ggtatttttt atggttaaat atacttttga
    15781 acttaaatta aagatcgttc atgattattt ggatggcaaa ggcgattgga ccgtaaaaat
    15841 ccagatcaag agattgaagc ggaaatgctt aaaattcggg agaagcacaa ggattatggc
    15901 tgtttacgga tgaccaatga actaagaaac cgcggtttct ctatcaataa aaagaaagtt
    15961 cagcgcttga tcaagaagct aggaataaaa gtaacggcat acacgcgtaa atcacgtcgc
    16021 tacaattctt atcgaggaaa agt
//
LOCUS       DACBYO010000067        15988 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.067, whole genome shotgun sequence.
ACCESSION   DACBYO010000067 DACBYO010000000
VERSION     DACBYO010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.067"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(192..491)
                     /locus_tag="IVD26_002052"
     CDS             complement(192..491)
                     /locus_tag="IVD26_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079989.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(497..727)
                     /locus_tag="IVD26_002053"
     CDS             complement(497..727)
                     /locus_tag="IVD26_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6079990.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1163..1729)
                     /locus_tag="IVD26_002054"
     CDS             complement(1163..1729)
                     /locus_tag="IVD26_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP6079991.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1729..2685)
                     /locus_tag="IVD26_002055"
     CDS             complement(1729..2685)
                     /locus_tag="IVD26_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAP6079992.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2685..3341)
                     /locus_tag="IVD26_002056"
     CDS             complement(2685..3341)
                     /locus_tag="IVD26_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP6079993.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3711..5729
                     /locus_tag="IVD26_002057"
     CDS             3711..5729
                     /locus_tag="IVD26_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP6079994.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            6156..8570
                     /locus_tag="IVD26_002058"
     CDS             6156..8570
                     /locus_tag="IVD26_002058"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAP6079995.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8918..10471
                     /locus_tag="IVD26_002059"
     CDS             8918..10471
                     /locus_tag="IVD26_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAP6079996.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10852..12636)
                     /locus_tag="IVD26_002060"
     CDS             complement(10852..12636)
                     /locus_tag="IVD26_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079997.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12651..14372)
                     /locus_tag="IVD26_002061"
     CDS             complement(12651..14372)
                     /locus_tag="IVD26_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6079998.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            14472..15233
                     /locus_tag="IVD26_002062"
     CDS             14472..15233
                     /locus_tag="IVD26_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP6079999.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         5228 a         2887 c         3107 g         4766 t
ORIGIN      
        1 gttaaggaat tgaatacctt aggaatacat aatagtgggt atagaatgtt agagaaaaga
       61 aaatgtgctg actatattcc taatgaaacc attacgaaaa cagatatggc gctgatgaat
      121 cgagaagcag aaaaaataat aaacaaactc acctaatgaa tttcaagcga gtttgtttgt
      181 tattttttta tttaatcttt gtatctttct ggatcaacga aagtatactt tatatagtca
      241 taacgccgat gatcgctacg tgcgtccggc acatcagtca cgatatcaaa caaaaaatat
      301 acgtctttct tcattctagt tttcgcagca gggattttaa agtagttctt attagaatag
      361 tagagattaa ttaataagct atcttcgatt gctaaaaaga aaacttctga atcccacacc
      421 ttataaaaat ctttgacaaa tctattcgaa ggatcaaatt taaaccataa ttgcgtctca
      481 ttaaaaagca taaccattac tccgatctat ttttaaactt agtctctacc tctaatatat
      541 atcgagtttt tattttgcct tcagagaata ctgtttcttt ttttgcagtt acaggttgtt
      601 tattttcgga aaaagctaat atagctaaaa ttgaaacatc catctggaat ttatcttttt
      661 tactgctttg atcataaaag tctgcatatt catcactgat attttttcta ataaattctt
      721 ccatcataaa aatcacctca aaacgattat acgaacttac gttcttgttg taaagcgata
      781 tttgaggggc aaaaaagggg cataatttga ctgatattaa gttagctatt gatatatgaa
      841 tgacatacaa aaatataaaa tcttttaaaa atgcttatat atcaatgttt ttgccattct
      901 tttatatatc tgttatatgt caaaaaaatg tgttcaattt caatttgtat ttgaataaag
      961 aggttgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaatcaaa aacagcttct
     1021 catgtttttg atttggttgg acttattacc gcagatataa gcttttgagc accgtgaata
     1081 aagaggttat gaaatcaacg ctctaacctg agtattagag aaaaaaacgc aaaacatatc
     1141 atttatgttt tgcgtttttt atttatcttt ttttctcaat acaatataaa ataggcggct
     1201 ggttcttttg gttgataaac cgataattca gcacattata tgtttcctgt ggcagtttgg
     1261 aacaaaaaga atcaaccata tccagttctt tttctccacc ttcatgacca tagtagacga
     1321 caaggatcaa tcgtccgcga ggcacaagtc gtttcaatat ttcttccata gctgtgcgtg
     1381 tagtctctgg catagtgatg attgctttat cactttttgg gagataccct agattgaaaa
     1441 tccctgcttt gagattttgt tgttcagcta tcacttctcc taacgtttcg tggccttgta
     1501 gaaacaatga gacacgttct tctaactgac gctgttctag cctttcacga gtagcatcga
     1561 ttgcttgttg ctggatatca aaactataga catgaccagt ttttccgatg tgttctgcta
     1621 gaaaaaccgt atcgtggcca ttgcccatcg ttgcatctac gacgtgatcc cctggttgca
     1681 agatttcttg cagtaatgta tggctgaaat gcaaagcagt ttgcaacatc agacgctcac
     1741 ctttttccgt acatcatatt ttccttggaa gctatctctg cgaagaagtt cttcatcaat
     1801 tgcattcaag acttcccatt ttttcaagct ccacattggt ccaatcaagg aatcccacgg
     1861 cgcatcccct gtcaaacgat ggatgatgat ctcttttggt atcatttcca gctggtcgca
     1921 aatgacattg acatagtcag gacggctcat taattgaagg cgaccttcat gatagtcccg
     1981 caacattctc gttttgcgca tcagatgcat caaatggagc ttgattcctt ggatatctga
     2041 atctaaaatg gtgcgtctga cattttcttt catcatttct aaactttcgc ctggtaatcc
     2101 gttgatcaaa tgcgtacaaa cacggatatt atgtttgcgt aatttagcca cgccatctaa
     2161 ataagtttga taatcatgtg ctcggttgat cagttttgaa gtttcttcaa aagttgtttg
     2221 caatccaagt tctacccata aatacatccg ctcgttcagt tcagcaaggt aatcaactac
     2281 ttcatctggc agacaatccg gtcgtgtacc gactgataat cctacgacac ctggtaaatt
     2341 gactacttgc tcaaatcgtt ctttgattat ttcaactggc gcatgggtgt ttgtaaaatt
     2401 ttggaaataa acgatgtatt gttggacatg aggccatttt tgatgcatca tgtcgatttc
     2461 tttctggaat tggattggaa gagggtcttc aggtgcaacg atcatgtctc ccgaaccaga
     2521 tacactgcaa aaagtacaac cgccatgggc aacagtccca tctcgattcg gacagtcaaa
     2581 tcctccatcg atcggcacct tgaaaatttt cccgccaaac tcatttcgta aagcgtaatt
     2641 ccaagaatga tatcttttat ttccttctga ataaggaaaa gtcattaaaa gtccttcttt
     2701 ctgtaagagt tatctatttg ttttcttttt tctctataca ctggataagt caggcacagc
     2761 caagaaagac tgagtaagta gccgccgatg atatcagtag gaaaatgaac gcccagataa
     2821 atgcggctta tcccgacact tactataata aacatcatca gcaattgaag caatgtgcgt
     2881 aaggttcttt tttgaacaaa agctggaagc agaaatagta aagaaccgta aagaatcata
     2941 ctgcctgctg catgtccact agggaaactg taacttgttt caactactaa gtgcgccaat
     3001 gaaggacgct ctcgcatgaa aaatagtttg atcaccgggt tgatgattcc agcaattaca
     3061 ataaatccag aaacgaacca aaatgtttct gccctttttt tcttatacca catccataaa
     3121 gccgcacaag caaataaaat gatgacggta agaggattac cgaatttagt cataaagagt
     3181 tggtagctgt tcagatcagg ataagaagct ctgacaatgc ctgtaaacca ctgatcgaaa
     3241 ccagaaagcc acgacagatg gaactttacg atccagccca aaatgaaaaa caggacaaga
     3301 aagaagctac cagccacctg aaatgatgtt ttatatttca tacaattcct cctttgaagc
     3361 aatgacttat tatagcattt ttggtccagc gaaaaaaacg gtaaagagat aaaaccaatg
     3421 tatgattcct ctttgaataa ccaatattct tataaaaaaa ataactgtaa tcggaaagac
     3481 attttttggt aatgcaaatg aaatgttagg gaaataaaat cagtgttttt cgaaatcctt
     3541 ttaaacaaga acgtagacgt aggaagaact tgaaaatgaa cagaagttgt tcattacggt
     3601 aaattacaat atgattacaa aaaacaacaa agctcttaaa taacttttaa taaatattaa
     3661 gagaagttat aattattaat aatagataaa ttgaagttgg aggatagaag atggaaaaca
     3721 ttgcaagaaa agaacggaga cgtttagaac agaccaaacg ttttcgaaaa gcaaaacgag
     3781 gggcagcaat cgtgggaact gcgatggtag gctgttctgt cgctgcccca ttagtacagc
     3841 cggttcctgt tcaagcggat gaaacacctg ttcagttcgg cgcaagaatc aatacagcgg
     3901 catttatcac agaaattgct acttatgctc aaccaatcgc tcaagccaac gatctatatg
     3961 catcagtgat gatcgcacaa gcagttgtag aaagcggttg gggcagtagt gcgttatctc
     4021 aagcacctta ttataatctt tttgggataa aaggcagcta tcaaggacaa accgtctaca
     4081 tggatacgct tgaattttta aataatcaat gggtaaataa aaaggagcct ttccgacaat
     4141 atccttcttt tgctgaatct ttcaatgaca atgcctatgt acttagaaat acttcatttg
     4201 gcaacggtta ttactatgcc ggtacttgga agagcaacac gaaatcctat acagatgcga
     4261 cagcttgttt gacagggcgt tatgcgactg atcctggtta cgcaggcaaa ttaaataata
     4321 tcatcgcaac ttacggattg acccaatatg atacaccagc tagcggaaac gcaggcggtg
     4381 gagcgactac aggtggcaat aatactggaa gtgcaggtag tactggcggt tcaagcaatt
     4441 ctggtaatac aaactcaggt tcagcaactt cgaccactta tactgtccaa tctggtgatt
     4501 ctgtttgggg aatctcaaat aaattcggta tcacaatgga tcaattgatc caatggaaca
     4561 acatccaaaa caatttcatt tatccaggac aaaaactgac aatcaaaggt agccaggaaa
     4621 atggctcttc gacgaataat tccggtaaca ataccaactc ttcaggaaat gctggtacat
     4681 caaacggagg acaaacaact ggtgcgaaat acactgttca atctggtgat tctgtttgga
     4741 agatctcaaa tgatcacgga attacgatgg ctcaattgat tgaatggaac aatatcaaga
     4801 acaatttcgt ttatccagga caacagctaa tcgtatcaaa tggcggttct tctaatgctg
     4861 gagcaaatac tggctcaaat actgggaata caagtggctc tagttcgtcc agctcaagtt
     4921 cttctaatac agcttcagga acgaaatata cagttaaagc cggagactct gtttggagcg
     4981 tctcaaataa atacggaatt acgatggctc agctaatcca atggaacaat atccaaaata
     5041 actttatcta cccaggacaa caactgactg tttcaaacag tggatcaaca aacagcacgt
     5101 caggtaatac aggttcgtca accaatacaa ataacagcag ttcagttaat actggcagca
     5161 gttcgtctca aggcacttat accgtgaaag caggtgaatc tgtttggagc gtggcaaata
     5221 aaaacggcat cacgatggat cagttaatcg aatggaataa tatcaaaaac aacttcattt
     5281 atccaggaca gcaattgatc gttaaaggtg gaacttcggc aaatacaaat acaggttcaa
     5341 ctacttctgc agcgaaacca aatacaccga atacgtctgc tacgacaagt acatcatcca
     5401 ctggtaatac gatgtatacc gtgaaagcgg gcgagtcagt ttggagcgta gcgaacaaac
     5461 atcatatcac gatggatcag ttaatcgaat ggaataatat caaaaataat ttcatctatc
     5521 caggacagca agtgattgtg aagaaaggtt catctcaatc aacaaaccaa caatcagtta
     5581 ctggttcgaa aacctatact gtgaaatctg gagaatctgt ttggagtgtt gctgacagtc
     5641 atggaattac aatggctcaa ctaatcgaat ggaacaatat taagaacaac tttatttatc
     5701 caggtcaaac gttgattgta gctaaataaa atagctgttc gaagaaataa cgattgaatt
     5761 ccacaaaaat atttgttact ataaggctac ttaaatatga caacacttga aaaggaagta
     5821 gtaaaaagac tgaagtttca gagagcgcat ggctggtgag aatgtgcacg gatgcttttg
     5881 aactcgcctt tgagttgccc ttgctgaata cccgagtaag caagcggcgg tgacggccgt
     5941 tacaacgttc gaggcctttt cactaaggta aaattaggtg gtaccgcgta gattacgtcc
     6001 tataaaaaga gcaatctttt tataggattt ttttatttct tttgtgaagt ttgagaaaac
     6061 aaagcaaaag gaaataaaaa taaacagatt ctgccggttt tttcgttata tttataatag
     6121 aaacaagtgt tttcaataga acaggaggac agcaaatgag ttacaatcat aaagaaattg
     6181 agaaaaaatg gcaaaaatac tgggcaaaaa cgaatacttt caacacccat gatgatcctg
     6241 aaaagccaaa attttacgca ctggatatgt ttccctatcc atccggtcaa gggctacatg
     6301 tagggcatcc tgaaggttat acggcaacgg atatcctttc acgtgtgaaa agaagtcaag
     6361 gatacaacgt gctgcatcca atggggtggg atgcattcgg tctgcctgct gaacaatatg
     6421 cgctagatac aggaaacgat ccagctgagt ttacccaaaa aaatatcgaa acattccgac
     6481 gccaaatcaa ttctttagga tttagttatg actggaatcg cgaagtgaat acaactgatc
     6541 cggagtatta taaatggaca caatggatct ttacgaagct ttatgaaaaa ggtctagctt
     6601 atgaagcaga agtagcggta aactgggtac ctgaattagg aacagttatt tcaaatgaag
     6661 aagtgatcga tgggaaaagt gaacgtggtg gctatgatgt agtcagaaaa ccaatgcgcc
     6721 aatggatgct gaaaatcact gcttatgctg atcgcttatt ggatgatcta gaattagttg
     6781 attggccaga aagcattaaa gaaatgcaaa gaaattggat cggtcgttca gtaggagcaa
     6841 atattgaatt taaagtggct ggtacggata aatcctatac cgtatttacg acacgaccag
     6901 atactctatt cggtgcaact tactcggttc ttgcacctga actagatctt gttagagaaa
     6961 ttacgacccc tgaacaaaaa gctgctgtag aagcttatat cgaagagaca gctaaaaaat
     7021 cagatctaaa gagaacggat cttgcaaaag aaaaaacagg agtatttact ggtgcttatg
     7081 caatcaatcc agttaatggc aaggaaatcc caatctggat cgccgattat gtattatctt
     7141 catacggcac aggagccatc atggctgttc cagcacatga tgaacgtgac tttgaattcg
     7201 ctcaaacttt cggactagaa attcttccag ttatcgaagg tggagatgtt gaaaaagctg
     7261 cttacacaga agatggtacg cacatcaact ctgaatttct agacggcatg aacaaacaag
     7321 aagcaatcga taaaatgaat gaatggctag aagaaaatgg cgtagggaaa aaagaagtca
     7381 gctatcgctt acgtgactgg ctattctccc gtcaacgtta ctggggtgaa ccaatcccaa
     7441 tcatccattg ggaggacgga acagtcacag ctgtcccaga agaagagcta ccattacggt
     7501 tgcctaagac aaaaaacatc aagccaagcg gtactggaga atctccatta gcaaatatcg
     7561 aggagtgggt caatgtcgtt gatcctgtaa caggtaaaaa aggccgtcgc gaaacgaata
     7621 caatgccaca atgggcagga agctcatggt attacctgcg ttatatcgac cctcataaca
     7681 aaaaagaact agcagattat gaaaagttga agcgttggct accagttgac atctacattg
     7741 gtggagcaga acatgcggta cttcatttac tatatgcacg attctggcat aaattcttat
     7801 acgatatcgg tgttgttcct acaaaagaac cattccaaaa actatacaat caaggaatga
     7861 tcttaggcga aaacaacgaa aaaatgtcaa aatctcgtgg taatgtagtc aatcctgatg
     7921 atgtggtcga aacttacggt gcagatacac tgcgcatgta cgaaatgttc atggggccat
     7981 tagatgcttc gattgcttgg agcgaaaatg gcttagaagg aagccgtaaa ttcttggatc
     8041 gtgtatggcg tttgatcgtt gatgagaaca ataaaatgcg tgaccgtatc actacattga
     8101 atgatggcaa gcttgataaa gtgtatcatc aaacagtgaa aaaagtgaca gaagactatg
     8161 aaaatcttca tttcaataca gcaatctccc aattgatggt ctttatcaat gaagcctata
     8221 aagtggacgc tctgccttat gaatatatcg aaggatttgt tcaactactc gcaccgattg
     8281 ctcctcacat gggtgaagaa ctatgggcaa tccttggaaa tgatggtggt atttcttacg
     8341 caccatggcc aacatacgat gaagcagcac ttgttgaaga cgaagtagaa gttgttttcc
     8401 aagtaaacgg taaagttcgt gcgaaaagca atgttccccg agacttagga aaagatgagc
     8461 tagaaaaagc agcattagcc aatgaaatag tgcaagaata tattgaaggc aaaacagtca
     8521 gaaaagttat tgcggtacca aacaagttag tcaatatcgt tgctaattaa ttggctcttt
     8581 gtcaataagg actgatgagt tgtgcaaaat caaatctggg ccagaatgaa cttcattctg
     8641 tctcagattt tttgttattt caaattgatt aattgattga tcaaaaaggt tttgattttc
     8701 atgttctcaa acacgttcaa tgtctttttc ttctgaatgg tcttgtaaga gatctctgta
     8761 atcatcaaat ttttgtctat taatcttagt attttttgat gtataaacta cctgaaattg
     8821 agagtacata ccaaattcat aaatttttta ttagtgggac tagtgattgt atggattttg
     8881 acgcataatg aatgaagtat gagaaaagga gagacaaatg gatcaagaac tatttattat
     8941 cgaagtatta tcagctaaac aaaaaattat cgagaaagcg aaaaaaagag cgaaaagaat
     9001 aatgttcaag cttttaagct tagtattttt ctctggtttg ctttttttcg gagctgtatc
     9061 gttcctatat cgccatatga gtgcagtagt ccgttcagct gaagggatgc aaaaattaaa
     9121 taatttgtat cacttttcgt ggggagttgg cggaataaca attgttgtgc ttattgtttt
     9181 tcttctactt atttggctcc gttaccatca attgtcgcgt catttcgatc aatggcttag
     9241 tcaaagagca caacagtttt tacataataa accaacttct caagatgatg actatcttta
     9301 ttttgagaag acttcgacga gtcaagcttt tcggatacaa aaaagtgatt gccagttatt
     9361 gctgagatca cttgatgatt tacctatcta cttaggcgaa agcaaatcaa aattcggaat
     9421 gaacacattc catatttttt tactagaaaa cgaacccaga tgggaaaaaa gccagtcttc
     9481 gcctggtgga tacctgacaa ctaagatgag tacattagtc actggttttt tcctcattct
     9541 tttagctgga acaatctatt atgggagata cactcagcca aaaatgtctt ctcatataaa
     9601 tgctgcttct cacatgacaa tgaactcaac taacgatacg catatacaaa agacaaatga
     9661 agggttgtta gctgatccta agcaaaaggt aaatttgaca acacaaaaga taaatgatct
     9721 caaacttgat acagagacgc actctctcta tatgacaaca gatagtggtg ctaattgggt
     9781 atttgtgccg attgattcgc aatggttgcg ttttggcgaa tacaccctga caacggggct
     9841 gattcctgaa ggttattgga tggacaacac atatgatatt tccgccgatt tctcatggtt
     9901 tatctattct tctggggatg atgtacgtct gctgacttca agagataatg gtaaaacatg
     9961 gcaaacgtct attatcaccc aatcagttca gccgatacgt tatcgaaaag cggtatttta
    10021 tggcaacgat ggtctattta tctgtacatc agccagtggg atgtctgcag aaactttgta
    10081 catttacact actatggatg gcggaatcac ttggataaaa agtggaagta caatgatcaa
    10141 tcagccagta caaaatgtca gcttcgttac aacttcttta ggttttgttt cgacacgtga
    10201 aagtttgttt tatacaaaca acggaggacg ctcattcaaa gaatcagttc tgtcgattcc
    10261 ggaaaactat cagacagggg ggatagatct ttttcaatca ccaaatgaag ttactcaaat
    10321 aagcgcgaat acgttagaga caaaatttta tttgttgaaa aaaggaccaa tcgatgcagg
    10381 gaaaatgttt gcctgcctct tccgttcaac tgataacggg gaaacatggc aattcgttca
    10441 gcaactatcg caagtagaac aaggagatta aagaagagag attgtgagcc tgacgttcag
    10501 caccgagtca caagaaacaa attcaaaaaa cagcttctca tatttgttga atagtgtaac
    10561 tcgtgattcg gagttgacaa gagcaacaag aagcgatttt gaagtatagc ttctcgtatt
    10621 ttacaagatc gtgtcttatt gccgataggt tgtctcttga acaccgttta ttcgtaaaaa
    10681 gggattgtga caagtctttt gtcactactt accgaacgaa actgaaggag ctatccaaaa
    10741 agtatcatta gtattattct ttgtgtttct agtggcacca ctagtacatt taaaaaagct
    10801 atcgatcatg gactaatcat acatgatcga tagcttttta gataatgttt gttacgctat
    10861 ctgaaattga ctattataaa gactggcata aagcgttggt gattggagta gttcagaatg
    10921 tgttcctttt tcgacgatat cgccattctt cattacaagg atcatgtctg cattttcaat
    10981 cgttgacaaa cggtgtgcaa tcacaaaact tgtcctatct tttgtcacag cttccattgc
    11041 ttgctgaatc aatgcttctg ttcgtgtatc tacgctagaa gttgcttcat ctaaaataac
    11101 gacaggagga ttcgctagaa tgactcgagc aattgtcaat aattgttgct gtccttgaga
    11161 taacgtgccg ttttcgctag aaatgatcgt atcatatccg tctggcagtg ttcgaataaa
    11221 gtgatcacat tgtgcgattt cagccgcttc gataatttgt tctcttgtgg catccatttt
    11281 cccgtaggcg atattatcag ctaccgttcc ttcaaacagc caggtatttt gtaaaaccat
    11341 cccaaaagaa cgacgtagtt ctccacgtga aagcttggta atatcaagac cgtcgaattc
    11401 gatctttcct ttattcagtt cataaaaacg catcagcaga ttgactaaag tcgtttttcc
    11461 tgcaccagtt ggaccaacga tcgctaccgt ttgttttggc tttactgaaa aatcgacttg
    11521 attcatcaat attttatctg atgtgtaacc aaactgtaca tttttgaaag ctatttttcc
    11581 tttcggttgt tctaaaagtc ttgcatctgg aaggtctgga atttcatctg tttcatctaa
    11641 tatctcaaat atcctatcga ttgctgccat tgcggattgg atcgagttga tcacataaga
    11701 agcggtagaa attggttcag aaatctgatt gatgtactga agataagctt gtaagaagcc
    11761 gatcgtcaca ccacctgata gaacaagcat agcaccgaat accgcactta tgatgaaggc
    11821 gagttgatta atgaaacgaa tggccggata gatagcacag ttcataaatt gagcacgttt
    11881 aaaagcgttg tattgctttt tatttacttc gtgtatagca gcttctgcat gagcttgctg
    11941 attgaatgtt ttgaccacta gattaccagc taagatttct tccattcgat tatttaaaac
    12001 acccagttca tactgattct gttcagaaat ctgtttgttt ttgttcgcaa tcttagttgt
    12061 aacaattgaa ctgccaacga tcagcaataa gacgagcaaa gtaagcttgc tttcgatata
    12121 aaacagcatc agaccagcag cagctattgt tacgacagaa gtaaaaaatt gattgatacc
    12181 tgtcaataac acttgagaaa gttgattgag accggtagtt gtccgactaa tgatgtcacc
    12241 tacttgatga ttgtcaaaaa acgacatcgg taatgttttg aatttttttg tgatttcttt
    12301 tcgcaccctc aatgtgatct tttcgcttaa cgctgccatt gtccgttcct gaataaatga
    12361 agtgatgctg cttaagactg aacagccgat cagcaataag acagggaaca acaatgcttg
    12421 tttgatatca ctgaaagaaa gctgtccaat acctgttttt cttatttctg ataagagatc
    12481 atcgatcccg attcccatga tcaagggcat ggctacgact aataggttcc cgaataaact
    12541 gcatagaaac aatccgtaaa aatatttatg ttcaggtttg atcattttcc aaaaacgtat
    12601 caaagcacgc gtgttcaacg tttttttctt ttccatcgta tcccttcttt ctatattcct
    12661 tgtgattttg caaactcctg ataagtttgg caattagaca gtagttcttc atgagtacct
    12721 tgtccaacga tttttccttc atctaaaaca atgatgttat ctgcttgttg gattgtactg
    12781 aggcgttgag caacaatcac gagagttttc tccgacatgt gtttatgaag ggctgctctt
    12841 aatgctgcat ctgttttata gtctaaagcg gagaaactat catcgaatac atagatctct
    12901 gctggtttga tcaacgctcg agcaatacat atccgctgtt tctggccccc tgaataatta
    12961 gaaccgcctt gagcaacaaa gctgtccaat ccgtcaggaa gggtgtccac tagttcttct
    13021 aattgagcga tcttgatcgc tttagacaac tcttctgttg aggcatattc atttcccatc
    13081 tgcaagttgc ttaaaattgt cccgctgaat aagaaagcct tctgagggac ataactgatg
    13141 tgggagcgga tctgttcttg agtcatttga gtaagaggaa taccaccaag ggttactttt
    13201 cctatcgtag ggtcactaag tctcaagaga agtttcgcca aactactttt tccagatccg
    13261 gtcccgccaa cgatcgctgt tgtttttcct ttaggtattg tgaaatcaat atcttctaga
    13321 actggatcag agatttcagt atatttaaat gtgacatgtt caaaagcagc tgcatttgtc
    13381 tgatcaaagg ttggttcagc tactgttttg atcgtctctt cctcaatttc gatctctgct
    13441 tgcagtattt cttctatccg tcgtaatgag gcaaacgatt tagggataat gaccaatacc
    13501 atagctgcga tcatcaagta agcaagtgtc agcatagagt attcgactac agcagtcacg
    13561 acaccgattt gtaatgctcc ttctgctaca agatttccgc caaaccacaa aatagaagca
    13621 taaacgattc ccatgagcaa aaaagcaatt ggagtgaccc aagcaaatat tcggttcact
    13681 ttgatcattt gattagcata gtcagcaaag ctcttattcg ttcgcttttc ttcatatgat
    13741 tgattatcaa aggcacggat catattaatc ccagtaaaga attctctcaa tgtgatggtg
    13801 atccgatcca tttttggctg gatactcaaa gataaaggtg cccctcgttt catcagtcga
    13861 taaacaatcc atacataaaa aacaacagag atcaatgtaa cccatgttag taatagagaa
    13921 taacgaaaca tcatgagaat ggtgaaaacg caaataaccg gtgctggtaa gatcatttgg
    13981 caaaataaaa caatcatttg ctggacatta tcgacatcat tcgtcattct tgtcaaaaga
    14041 gatccagaac taaaacgact gatatccttc attgacagct gttggaattt acggaaatat
    14101 ttctcccgcg tttggaatcc aaacctagcg gaagccaatg ctgaaaagta actagaggca
    14161 actgcagcga ttgttcctag aaacgctaca agcagcattt caactccaat tttttttata
    14221 actgaggctt cgccacttgc tatacctgtg tcgatcagct ttgctactaa ttttggtaca
    14281 cctaatgtac cggcgatttc taaacagatc atcacaaagg taaggagagc gagtcctttg
    14341 tttttctgta agaatgtttt taagatagac atattattcc tccttttttc ctgatacttt
    14401 tcgattctat accttcaagt aacttgaagg tcaatagaaa aaagaataaa ctgaaaaaga
    14461 ggtgagaaaa aatgaaaaaa atgtatacga ttggccaagt atcggaacta tttgatttgc
    14521 caaaatcaac gatccgctat tgggatgaac aaggattaat ccgttcaagt agacaagaag
    14581 agaatgatta tcgattgttt gatatcgatg atatttttat gctttatgat atcgtttttt
    14641 atagaaaatt agatataccg atcaaacaga tgaagaattt atatggaaaa acattgacgg
    14701 agttatatga gacacttgat gaaacagaaa gaagaatcca taaagaactg gtggtgatga
    14761 aacaaaaaca aaaagagata agggagcaaa aaaaacagtt gaaattgatg atcgatacaa
    14821 acgaggaaga atttcctgta gaagagatcc cttttgactg tatgatctca acggagtttg
    14881 aagatattgt ggaaatcaaa aaatttctac ctaactattc aagctttggg atgatgagta
    14941 tgccagcttc cagttcacag acgatgtatg gattttttat cgaccctagt gaagtacatt
    15001 tatttactca agacgtgatt tgggagaaaa aagatacggc tgtttatcgt cgattcttat
    15061 tgaaatccga gatgaaccat gcggaacgta ataatatttt agaaatcaga gaaagaatgt
    15121 atgaaaaagg atggaaaaca ggagaagtga tcggccagta tctattgacg aatacggatg
    15181 aaaacaatat cagaactgaa tattatcatg catggataga aatgaaaaaa taggaaatat
    15241 gtgtttaaga taactcgaaa atgatggttg ttttagttat aaagaaaaat tttctggttc
    15301 gattacgggt ttaatgtggg ggattattag tcgtggatag atagaatttt agttttttag
    15361 aggaaatatg tctttaaaaa tggaatggtt gcaattctta gcgatatata cgatgtaatt
    15421 gtcctcttaa aaaagtatgg aaaaataatt gtattgggtg ttatgtataa ttcatggtga
    15481 actgagacta atgagaagaa aaattcatat tgttatgagt gagattgtat cagatgagaa
    15541 tgataaatta aataggtgca taaaagcatt acacttaaaa tacattgttg cttacattat
    15601 tacaatatgt taataaggca aaaataaata gatggattga ataaacatat tttttaatca
    15661 aatagtccct actgtgactt tcctcagcta tcggtgatac taccgatagc atttttttgc
    15721 ttataaaata attataagta tttagagatt tttcttctaa cattcttcaa acaagaaaaa
    15781 tcacaaaggt tattgttatt tttatatatt ctttttaaga atgattgttt ttttatagaa
    15841 attttaaaaa ataaaacacg ttattgatgg atagttagtt tgttatttgg taatattata
    15901 gaagttgact ggtagtgatt tatttttcgt cgttttataa aaatgttatt ttttggaaaa
    15961 attcacaaat atgtaacgaa tgtttttc
//
LOCUS       DACBYO010000068        15705 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.068, whole genome shotgun sequence.
ACCESSION   DACBYO010000068 DACBYO010000000
VERSION     DACBYO010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.068"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..2564)
                     /locus_tag="IVD26_002063"
     CDS             complement(<1..2564)
                     /locus_tag="IVD26_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080000.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIP"
     gene            complement(2786..3670)
                     /locus_tag="IVD26_002064"
     CDS             complement(2786..3670)
                     /locus_tag="IVD26_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAP6080001.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(3765..4202)
                     /locus_tag="IVD26_002065"
     CDS             complement(3765..4202)
                     /locus_tag="IVD26_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080002.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(4419..5330)
                     /locus_tag="IVD26_002066"
     CDS             complement(4419..5330)
                     /locus_tag="IVD26_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP6080003.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVMSTFTSDSSTASSK"
     gene            complement(5707..6345)
                     /locus_tag="IVD26_002067"
     CDS             complement(5707..6345)
                     /locus_tag="IVD26_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6080004.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(6349..7119)
                     /locus_tag="IVD26_002068"
     CDS             complement(6349..7119)
                     /locus_tag="IVD26_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAP6080005.1"
                     /translation="MIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQE
                     ISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSTYWERNILSGEIYPPLK
                     IKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFS
                     FFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIER
                     EPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            complement(7537..7953)
                     /locus_tag="IVD26_002069"
     CDS             complement(7537..7953)
                     /locus_tag="IVD26_002069"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080006.1"
                     /translation="MMTREKEAYERFILLFVERFNQAFHTDYATNIFEDFENSYSYSV
                     ISSTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNGFSLHQVLWCLLGKKKI
                     IITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGI"
     gene            complement(8004..8385)
                     /locus_tag="IVD26_002070"
                     /pseudo
     CDS             complement(8004..8385)
                     /locus_tag="IVD26_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8511..9176
                     /locus_tag="IVD26_002071"
     CDS             8511..9176
                     /locus_tag="IVD26_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6080007.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(9573..11606)
                     /gene="brxL"
                     /locus_tag="IVD26_002072"
     CDS             complement(9573..11606)
                     /gene="brxL"
                     /locus_tag="IVD26_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HAP6080008.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(11724..14246)
                     /gene="pglZ"
                     /locus_tag="IVD26_002073"
     CDS             complement(11724..14246)
                     /gene="pglZ"
                     /locus_tag="IVD26_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HAP6080009.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(14362..>15705)
                     /gene="pglX"
                     /locus_tag="IVD26_002074"
     CDS             complement(14362..>15705)
                     /gene="pglX"
                     /locus_tag="IVD26_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HAP6080010.1"
                     /translation="NGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQNQAIFETKGS
                     VLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVTSERKLKKIR
                     EKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLVNQFNTLKSN
                     EEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCIFGRYSLDED
                     GLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVEITFGKETLE
                     ENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGKQNGFKALMY
                     LHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTKEIVKIQKQL
                     KEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKGVKEPKK"
BASE COUNT         4829 a         3143 c         2377 g         5356 t
ORIGIN      
        1 gggatagaaa gaacaaattt acctgtatca tcaatagttg tttcggacaa aacagcttga
       61 ttttttttca atgaaaccaa agctcctgct tcgcctgtac ctgtgattga gcgagaagct
      121 gcattgatca atgtggtact taatttagca ggctcaggag gaatcacatc gactgtcgtt
      181 ttggcagagt ccagttctgt cacttcttgg ccgcctctta cttttttagc agcaactatt
      241 tgcacttgat cccccgttgt tagtctttct tcgttgggta cttgaacctc aaacaaaccg
      301 ccttgttcgc cttctcccca cggattatat cctgtccctt cattttcatc tgtttgtcct
      361 tgtgtgagag cagtaatttc tacaggtgat ttcgtcgtat ctgcataagt aatacgtaaa
      421 gtcacttcta cttcgcctgt ccaagcatct cttggctttg cctcgacacc ttcgggaaca
      481 acgacatgcc catagatttt tttatctgca ttcgttggta ctcttaagga ttcaatcatc
      541 ggaagctggt tattggcact gattcgatta taatttttca ttccggcacc tgtctgagca
      601 aattcatttg ttaaacctgc actagggctt gatacaaaat tacctaagtc ggttccattg
      661 atcgataagt ctgtcatatc agaaaaataa tccggatctt tttcaaagtt atcgaacgtt
      721 actcctgcct ttcgccataa agcaatttct gaatgagcga tcttcaaaga agaatcgcca
      781 tttccttgaa atacccagcc acctatgcca ttagtctcgc ttccgatccg tttgttttgg
      841 aaatcgaaat aggtaggaga ttctaagtct acattcaaca catccccact gatgatgcca
      901 gtcttatctt ccccagtttt cccgaccatg actaaataag ttttttcgcc agccataaag
      961 ttcaaatcaa tatctccagt tgtatctacg gtagctccgg aatctgcgcg tatatcgata
     1021 tttgattttt ctccagtaac cgtaaaatca gctgaccctg gactttctag aaaaccagaa
     1081 gcgtcataaa attggatcgc ttggtttcct tgattgagtc tgttcacata agatttgcca
     1141 tcccctgcat ttcttacctt caatgagcct ccattagtta ctgttagttt ttgcgtaccg
     1201 ttctcaaaac gaactgcgct agaacgacca ctttgcttat caatatcgat gactgatccg
     1261 gctccttcta cgatcaaaga aagtcctttc cctacaaaac gcatcccatt gtttccaggt
     1321 tggtcgccat ctccagccat tttgaccgag atttgtccac cacttgatac atggatttga
     1381 ctagaatctc cttgcaggcg aaatccgcca gtagtcgctg tattgattgt gattttccca
     1441 tcattcgaca cagcgactct tgatcctgag cctctcattt ggataattcc gcgattgttg
     1501 tcgttggtaa tattgatctt tgtatttacc gaaaattcac ttcctgagcc actgacttta
     1561 aatgtgacat tcccgggtag cgtatcgaca gcctctcctt catcgctgac gccatctgcc
     1621 cgatcatagt caagagagac ctttgaacca ctcaagatat ggagtcctgg tgctgttttt
     1681 ccactgcccg tctcatcacc tgaatctaga aaaccataga attttcctag atatggtcca
     1741 taaagctgac taccattgat tacatttagc tgatagcttc tacaaaaata agctttaccc
     1801 ggagcggcat tcatcccttc tttcactggt tggacatcca atacaccgga aacaccatct
     1861 aatgtgacag ttgcacgagg ggcgtaaatc aggcctaatt tagaaccatc atataagtca
     1921 agtgtcccgg taaattttat ttctcccgta aaatgatatc tgtttcccca aaaatcggac
     1981 atataagcaa tgataatggc atttccatcg atatttggta tcaacccacc tggatgagct
     2041 gccgttcctt taaaattctg aaactcgatc gactgaggtg tctcattgat atagatgtga
     2101 tgtgtgccga aattatgagc aagtccgcca aaatcgataa cgatatctcg cttgatctcc
     2161 aattccctgt ctaaagtcaa aggctgagtt aaacgaatct tagctactga ttcgtctgcg
     2221 agaagctgcg tcagttcttc tgttgtggca gcttcgctgt acccatccgc tgaaacaact
     2281 ctaacctgta cctcttcact gctatcagac gtttgttcag ctacttctga ggtctcactt
     2341 gtcttatttt cttcttgcct tgtattagaa gtaggcgcct cactttggga ttctgtagtt
     2401 tcagaagtaa ttgattcttc tgaaaaagta gtcttgtcaa aactttgatt ctctgattgc
     2461 gttgattcgc ttgttttctc tacatcggca aaaacggatg tcaccatcaa gagagggaag
     2521 acaaacaaaa tcgacgcaat cagctttttt acatattgat tcattctcca ccatcctctc
     2581 tgacgttttg acaattttat tttaacgttt taatttattt gtaattgtac tttcatattt
     2641 aaaatatgta tttttatggc aaatttttct gttaggtgaa aatttctttt ttgtacaaaa
     2701 aaaggctgtg acaaaagtct tgtcacagtc ccttattccg aacaaccgat gtcctcctga
     2761 caactcttcg gtcacaacct ccattttaac aataaacctg taaatgtgag ggtaacactt
     2821 tgattgtcac aggtaattta tccccttcat ctccatcaac attcgtcgtc aattcttcct
     2881 catcagctaa tgacacaact aattgctcac aagtaagata ggctagattt ttcgtagatt
     2941 catctactcc ttttaatagg tctggcaatg ttttaagcgt atcgatcaaa gaagaatctt
     3001 ttaaataaac caaatggagc ttaccatcat ccacttttgc atttggaagt aatgtttcaa
     3061 aaccgcctac tgagttagtt agtcctatca gcaagatact gctctcaatt tcttccttct
     3121 ttccatcaac ttctacgtga aacgagtagg attgtgtgga agctaactgt ttgattcctg
     3181 acatgaaata agctagtttt ccaaatttcg tcttcttctc cgcatctaca tcattgattg
     3241 cttcagggat agagccaatt gcgacgacat tcataaaata gtcgtcattt atttttccaa
     3301 tatccaatgg cttgactgat tcaatcgaaa aatgattgat cgcttcctca ggttctagcg
     3361 gtatccctaa tgctcgagcc aagtcattca ccgtacccaa tgggaaaaat ccgaaatttg
     3421 gccgatgttc ttgttcagcg attccactga ttccttcgtt gactgttcca tctccgccca
     3481 tgacaaacac actatgatac ccttccgtag ccgcttcgcg agtaaagttt tttgcatccc
     3541 ctgctttttt tgtatgcaag acgaccactt catcaaacac cgattccaat tttgctatcg
     3601 ctaattgctc aaattccttt gcttgttcac cgcctgaact ggggtttacc actaataaaa
     3661 cttttttcat cactttcttt cccttctgat tgatttcttt aatataacga tagcataaag
     3721 aaaaaaatta ggctgtgatg aagtactgtt catgaaacat tcatttattt tttgacaaga
     3781 taaaataccc atactatgaa actgaggaaa attaaaacaa tgatatagga aataaaagaa
     3841 aatgataggc attgtatacc taataaagta aaaatcttag gtggcagata aaaacacaaa
     3901 aatagcaaga gaatgtaata gcgtttcttc cactttttgt tatcagacct tatagcgatc
     3961 agaggaatac caaatgcata actgaaaaac tcttgatgta ctgttaatat gtcacgacct
     4021 tgaataataa atgcaacaat ccccgctata attagtgtgc ctaataccaa aacggaaaat
     4081 tgatgaatat attttatata caaatgatcc attgtacttc ctgccttttt atttgtgaga
     4141 aaaacaaatc cgtatacgtg aataacttct agaaataaaa gaaatttgca aaaccactcc
     4201 atttatctac ttctacgtgc attttttaat atcgttttct ttatttaaga ttatacagaa
     4261 aaatatctag ggtggctgga ttctaagtaa aaaaaatttt taaaataaaa agaactaaat
     4321 caagtaataa ttaaactact gttgatttag ttctaataaa aagatttaga tgaacagttt
     4381 tattgattta aatagttcat attttttatt tataccgctt atttactact tgctgtacta
     4441 gaatctgaag tgaatgtact cataacattt tcaaagtctt tgtctttgat ttttacatta
     4501 gcgtctttca atacttcgcc aattacttta ttctggaagg tactgtcact taattttgtg
     4561 tctgttgcaa tttctttcaa ttcttttttg tatttatcca tgtcgttgcc tttgttttgg
     4621 tttttcacca ttttaaccac ataatattcc gtagtataag ttgaagcatt ggtagaagtg
     4681 atcacatcag aaacttgacc atctttcaac ttaaaggctg cttctttgac ttctgccgga
     4741 accgttgtag tagtggaatc aaatttcact tttccgccat cttcttttgt cgtagtatca
     4801 gttgacttgt ctttggctaa tttagagaaa tcgtctccct tatcagcagc tttcttcaca
     4861 tcttttgcat catcttcact tgctacttgg ataatttgag cttccacttc tggatggaaa
     4921 gattcccaag ccgtttttaa atcttcatcg gtcaatttga tatgtttctt tagaccttct
     4981 tgaaaggcta gactttgttt gatactgtct ttgaatgttt gttctgtgta acctgcagat
     5041 ttcaattgtg aatcaaatga atcacccaat tgtttctttg tttgatcata ttgggaatcg
     5101 atttctttgg ttgatacgtc atctccatat ttatcttcaa atacttgata aacgatcaac
     5161 tgttgcacag cggaatctgc tccttgcatt tttttcaagc tatccattac ttcttgttcg
     5221 ctgattgtac cgcctttata actaacggct gttttttcac cggcattcgt acagcctgac
     5281 aataagccag tgcctagtac gatggcaagt gctaaaaatc tttttttcat ttatcaattc
     5341 tcctactttt cgttttttgc gaattgctaa aaacaaaggt gttcaagatg aaaatcatca
     5401 agaacacctt tactaatctg ctcgatacgt cctgaataga tataaggcta cacaatccag
     5461 aaagttcgct cagcagaata aatgtcaagt agcacatcac accttaatat actacttctt
     5521 ttgttaccgt ttttcaagtc tatcttgcgt tccgtattta acgtaactaa ttcttagaac
     5581 aaatgttatc gattttgttt ttcttcttcc gctgttggga tattcaaatc agacactttt
     5641 atgttcgatt ttccagacat ttttttgttg tttttattag aaaaagtttg ttttttcatt
     5701 tgttttctaa agcatgatct tcttgtttcc tattttggtc agatatggat catgcgtgac
     5761 cacgataact aacgtacctt gggaagcctg ttgcgataag atttcaacga cttgctcctt
     5821 atttcgttta tctaatgatc cagttggttc atcggctaaa atgattttgc tattcttcaa
     5881 taagactctc gcacaggcga ttctttgctt ctcaccacca gataatgtgt agataggcgt
     5941 acttagcttc ttgtttatat ttactttttt caatgcctca tactttgctg ttcgcttatc
     6001 tgaaacattt aaattcgaaa acttcaatcc aatatctaaa ttaaaatcga ttgtttcata
     6061 ttcaatcaac ccaaaatctt gaaaaagaaa agagagggca tttcttttta tcaagcgctt
     6121 ctctcttcca gttaaatgtt ttgtttcttg attaaataaa taaaattgcc ctgaactgaa
     6181 ttgatcattc aatcctaata tattcaataa agtacttttc cctgctccgc tctctccaac
     6241 tacagtcaca aaatccccag catccgcagt gaaacgatcc aaatgaagaa tcgttttgtt
     6301 tcgaatgatt tttttcgcac cttttatcac tatcaacggc tccaattgtt aacctccatt
     6361 catcagcaat aactgacttt tcttttctgt agacaaaata aaaacaactg aaagaataaa
     6421 atcaatgaag ctaaagaaaa aaatattaaa aagatattta ggctctcttt ctataagaaa
     6481 aaggaagatt acacttgtcg ttccccattt gatgaggttc atcatgaaga aatctttata
     6541 cgtttcaaag agcgaataac cacttgaacg aaagatagcg attttccgac aattgtagac
     6601 aaaatatatg cataacatga catagctcaa caagaagaaa gaaaagaaag tgagtaaaaa
     6661 tatctgtatc aagtaatgaa atgatctgct taacactttg acagctatct cttcagtctg
     6721 agtatacgga aatgataact gcaagttatc acgtaactga ctttcttcaa tcagctcaaa
     6781 taacctttct ttcgacaaag agcctatctt gatctttaac ggtggataga tttctccgct
     6841 gagaatattt ctttcccaat acgtactgtt tttcaatgtc agtatttcaa caaccggata
     6901 atgttcgatc caggggatag aaggaataaa tgtataaatg ggttgattgt tttttataaa
     6961 tagaaatttc ggttcttttt cactgatttc ttgataatat tctgttattt gcgccaggtc
     7021 attttttaaa tctgtatgtc tatatcgttc agggatcaat ataacagggt gcgtttcttt
     7081 ttcggttatt tggatcaacc ttccagagac atcaatcaaa ggaaatttct taagataatt
     7141 cagatttatt tttatccctc tgccaaactg ttcattttct tcattcaagt aatctgatac
     7201 attgactaat atacttccgt ttttattcaa agtttcatat aattcctgat cggctgctga
     7261 tgcaaaacga ttggaataaa taaaatccac gtggtttttc ccgatggtta ctggataaaa
     7321 tacatgatag tcctcaccag cgatttcttt tggtgtttca tgggaaacag ctaactgtga
     7381 agaagaaaaa acgatagttg ctaattcgac attggcaacg gtcaaaagaa gagaaaacaa
     7441 caatccaaat gtaaaaagaa tgtattggat atagttgaac gcttctctta acgaagcgat
     7501 tttttcaact aataaaagag aaatcaaaga gataccctat attccgctga acaagaaaac
     7561 gtacatctgg aacaaataaa gaaattgctc cttataatac ataaaaataa aaccaccaat
     7621 gattcctgca attatgaatg taataatgat tttctttttc cccaataaac accacaatac
     7681 ttgatgtaat gaaaagccat tattcaacaa taaactgatt tctttattca tcaataagaa
     7741 aaaggatgat aacaaaagga ataaaagaat caatccaata gttaaataca ctcgataatt
     7801 atatacgtct gtacttgaaa taaccgaata cgaatagcta ttttcaaagt cttcaaaaat
     7861 attagtggca taatcagtgt gaaatgcttg attgaatcgt tccacaaata gtaaaatgaa
     7921 ccgttcatag gcttcttttt ctctcgtcat caagaaaaat tcaccttcaa aatcttttat
     7981 tttgatcgat tcttcaatgg acgttacgcg aaaggaggta ttagaatagg gtaccttctc
     8041 gtgagaagat ttgacatccc cttgataata caatgtcatt tcaagctttg gctgtatctt
     8101 gaagttccaa gatgtatcta cttcattgga ttcatttact gtttttttca tataagaaag
     8161 ctcagtttct gatgagacat tttcaaatac catgattagc tgctcatatt cttcttgccc
     8221 aataaaatgt tgtggcaatc gaatcggagt ataagtatct gtttgatgga aaaattcatt
     8281 tgtccgatag agtacctgtt tatttataat aaccaaggca aaaccactca tgataccggt
     8341 cactatgatt gtgagtaaaa ctgtgaactt ttttttgatt atcaccactc tcccttactt
     8401 aaatgattct ttgataaaat cataccgttt ttcatcaaaa aaacgtatct atcaaatgta
     8461 taggtcatgt agaataaatc tatatactgt agaatcgaaa ggagaagaag atgaacatcg
     8521 gagaaaaaat acgaacttac cgcagaaatt gtaagcttac gcaaaaagaa ttaggcgaaa
     8581 aaatcggtgt ttccgataaa acaatctcta gttgggaaaa ttctcgtaca atgccagacc
     8641 ttgaaatgct gtcactttta catcagactt taggtctgcc gattgatttt ccttctattg
     8701 aatcagctac cgaatcaata gaaccaacat tgccggatga acctcttgtt atcaagaaat
     8761 cttattcatc aaaacaaccc ttctcactca aaaagacact atctttcttt ctgctcgtct
     8821 tttgtttggt ctatcttttt cttatcaatt atcaatataa aaatgaaacg gttgatcgat
     8881 tcaatccttt tttgaaacca caaatcggct ataccacact ccctgtagga tacgtggaaa
     8941 attccatcga acattgggta tgtaatgata tctttgttca tggtacatgg ctgtcttttc
     9001 acgctggaga ggtagaaaaa ggtaagaatc atgctgtaat caaacacaaa ggaaaacacg
     9061 tcatgaacgt tcgcctgctc acttgggaag ccattccctc agattaccaa gaaatcctca
     9121 tccaagacta tgacgatgcc ttaaaaagaa gccctcagga gccagatagg cattaagtag
     9181 gagatgaacg tagagataga aaaaatcaat gcacatgatc ttatcaaaaa aaaacagggg
     9241 tacaaattaa ttgaaaaagc tttgagatga aagttcctaa ataaaaaagt tcagaatgat
     9301 aggtaaaaaa atgactaact attctagtat taggctattt gtattattct tctgttattt
     9361 ttatatcaaa aaatccagaa ataactaaat ataggtattt ctggcttata gtataatatt
     9421 tacgccacag cccccaatga ttctttttgg aatcatgatc aaggacggac atacacaaaa
     9481 atattttgcc cattcgatcc gaatagatta acgactaatc tagtaagtaa tatagattgg
     9541 tacgtagtca aaccagcaaa tggaaaagtt gtctattcca ccccaagggc tttaaagaca
     9601 gcatcttccg gcgtttgata aaaaatcaaa ttaaaggtac ccattaattc tgggggtaca
     9661 gttccaatat cagcagcgct tatcataggt acaagtactt ttttcgctcc ggcatctttt
     9721 gctacttgta aacagttagc taaattatct accttaatca tagaaccacc aattgtaata
     9781 tcccctaaaa taactaaact tggtaataca ggtttattta aggaaactga gcataaagct
     9841 attatagttg ataacgataa tgtttttgtc ataccaatgc cattcatatc ttgaacatga
     9901 acgacaaaat cttttgtcgt caaactaata gactgactaa cacttccata attagctctt
     9961 aaatatcggt atgccgaatc catcgcttct cttgctccag catctgaatt gatcccagta
    10021 cgttcaaact ttccatttcc cgaagtcatt tgcgtttcca atttataggt acctaattgc
    10081 ccagttttgc cataagatac cgtgtacaaa tgccctggct tccctaaccc ttctggaatc
    10141 aaagttcctc caccttgttc aggaacagaa acatactctt ctcgctcttc ttctaaatca
    10201 atgtatgaaa aattgacatc ataaaattcc attccaccaa ttttctttaa ttgttctttt
    10261 acacgacgac gcatttcaag agcaaatctt agtatttctt cgacatcact tttttcaaat
    10321 ctaccatcag gatacaacag tttcatcatc ccagatacaa tccgacgaac tgcaatcgta
    10381 tcccgctgat ttaattgaga accaagtttg aaatatttat caaaactatc gccaaaacta
    10441 acttttcgaa gctcacgcat gacttcagaa aaataatctg taatgaagcc atagtcattt
    10501 gtaaaaaaat ctggtcgata tttaggaatt tcccaacctg gtaaataaca atgcatccga
    10561 tccaaaaagg ctgaatccgt ccccataacc tccggaaatg gctcaaataa attcgaagtt
    10621 ttcaatatta catcaacgct ttgattaata tttcctacaa aagccattga tgctgaagca
    10681 ttcttttctt ctttgcctct agcaaaagat cctgaagcca tgtaatcttt catgatttga
    10741 acgccatcat tatccttaaa tttaatccca gcaacttcgt caaaagcaac acagtcccac
    10801 atacctacaa gtcccattgt acgactagcc atattataga aaaggtttgc tactgttgtt
    10861 tgtccacctg aaacaaggat tgagtttggt gaaatttctt tatatacatg cgatttacct
    10921 gtaccacgtg gtcctagttc acagagatta aaattatttt caattaatgg aataagtctt
    10981 gctaaatgaa gccattttac ccttttatta aattgtgtag gttccatacc aatggaccgt
    11041 agaagtaagt caatccattc atttgtagta aactccttgc gagccatctt gtaagcctca
    11101 atgtctaaac caggcatttg gattggatca accttttttg caataaaagg gctattccaa
    11161 cgatcattct catcatacca atattccatc gaaacaatac accagatccc cccacctaat
    11221 aatcgatcaa attttttcgg atactcttca ctaatttgaa cattttttaa tcccaggtta
    11281 gagaattctg cttcataaca atctttcttt tcatttaaat gtacagttac tttatcaata
    11341 actgtataac cacccaattc acgaattttt gcttttactt tttctgcttc atcaggacgc
    11401 acatagtttc gagcaagaat atttttaaca ttttccacac ctttttcaac caatgtttca
    11461 tccaatgacg aagcatacat accaagtaaa tattccaata cataaacagg tacattcgca
    11521 ccttctttaa ttttctttgt taaatctttt ctgacaatct ttccgggaaa gaattcagat
    11581 aactttaaaa tttcctgttg ttccactaga attcctccat gtgttcagtc attataatag
    11641 caattaaagt atatcatact taaccagtag gcttgataat acaaaagaaa aagtatccac
    11701 aaaaaattgt ggatacctcg tttttatata tcaaaatcaa atgattctgc aaaaggatta
    11761 tctataatga attttattcg ctcggtcaaa tcattttttt gattttttat cactaaataa
    11821 taagtatctt caactgtata tcgacgattt acaaattcaa aaacaaattt agtaaaccgc
    11881 tgatttgcat cttctgtttt tgaatccgca acatagattt cttcatttga gatacgttca
    11941 ccatattcat cttcaaaata aagccagaaa gatgcggggt cataaacatc actaattgca
    12001 tttttttgat agaattctaa cgtggttgat aatcctgtaa ttctgcggtt gctagtcatt
    12061 aattcaattg ctactggttc ctttgcattg ctacctttgg ctaccgtaat ttctagaaca
    12121 gggactagca tttcttgaat agatgaccct ccatgaacgt agctttgtcc cccgccagct
    12181 ttcttaaaaa tacttgaagt aatcgggaca caaatgtttc tagtgtcatc atttcctaaa
    12241 gaatctccca aagagtaatt tttcgtacca attatttcgt attcttcttc actaagaata
    12301 aaacgacgtt ctacacgatc tttttcattt ctagatggat tttcaatctt atctacttct
    12361 tcaacgtggc ttcttttata aataaatcca tgatcagccg taactataaa acgatagata
    12421 ctgccatcat tatgcaagcg attaataagt cgggaaattt cgcttatcgc taaatcacag
    12481 gcctcaaaaa ctcgattttc attcgagtga tcacctgttc tatccacttg atcgtgataa
    12541 atataaatga ctgatttgcc attaaatact tctcgtacct cagccttatt catcttaacc
    12601 acatcatcat aatttaaagc tacagcattt gcatctcgtt gctggagaat cgcatttcga
    12661 ttggataaac cattcgtttt tttcccatca atcagtactt ctgttccttc attgtaagtt
    12721 agttgattgt ttggtaataa ggcggcttta ccgaattcag taactgaagg taatacagaa
    12781 agaaagctag ccatgtttgt tgaatacttc ttttctctaa ctaacttacg ttctaaattc
    12841 atccctaact catatcgaaa agcatctgaa ataataacta cagttttaac agagcgtttc
    12901 attacagctt gattataaaa ttttcgaatg gatggacgat tcttaaattc aaaagtttga
    12961 ttccaaattt gtcctgattg atcaagaaac ttcgaataat ttgcttcaac taatcgatac
    13021 aattggccat atttttgctt ttcttctata tgatcactat tccaaataaa tttccgataa
    13081 tgcgtatcaa cccaatacat ttccttctca tattgagtta gcaaattatc catgttcatc
    13141 ggcaagcaca atctgttttt atccacaaga taataagcat gtttcaataa ttgatactca
    13201 taaatataat ccgatgcgaa atgcattttt tcgcgctgct ttaaactatc aaaaattgtt
    13261 tgtcctgcaa ttttcgttgt agtgtcagaa gcctttaatc gttctgcata aaacattaat
    13321 atttttgcat gaatctcaga aaatacgtct gcttcaatta gatcatcaat ttctatactg
    13381 tctaataatc catcaccatc aatagcctga tatacttttt tagatagctg ttcaaagctt
    13441 tccatgtaac gtgtatcatt cataaactga tccatgaaag taataatgtt tgctttcaaa
    13501 tgtagtattt caaatccttt gaacttcttc ggcatctctt gatcaatttg ataataaaaa
    13561 tagttcaaat aaagacacat cgtcagcttt tccaatgttg gctggctatc cgtaaagcca
    13621 aatttcattt gaataaattc ccaaaattta gctgttaact gatacttatc aagttccctt
    13681 aaaggattct ccctactttc tgtaaagctt tttagaacta cacgcagtaa atcatttaat
    13741 cgaatacttt tcgatttcaa caaaacagcc attatcatta attcaatcgt ttctgattta
    13801 ttaattgtca tatgcgtact aaattcacca aaacttctca tgcgatcctt tgcattaaag
    13861 aaattacgat actgtttaac tgtctgatga aatctaagtg gaatagccaa ttcattcatg
    13921 ataatcgcta agcggtctgc actaaattcc tctgaataat tcaatacact caacaaatga
    13981 ttatcttcat ctttatcatc ccaacgagga aatggcgcat agattaaata gttagtttcg
    14041 ggatcttcat attccaataa acgcttagtt ttaaattgtg cgtccttttc taatcgatag
    14101 atttttgcat tttgaatgac caatgagtca atttcttcaa gaaaatcctg atttgaatca
    14161 aaccaaaaaa tgattttcct acatccataa ttaggaaaac gttgatttaa tttttcttca
    14221 atttgttgcg tatttatatc tgtcatcaat ctcacctaat cgttctcttt ctatacccct
    14281 tatattgaca taatttggat aatttcgcac gcaatttaag aataaaaaag aaagttgtta
    14341 gaaaacaact ttcttagata actatttttt tggttctttg accccttttg caaaaatttg
    14401 gaatttctcg ccggttttag gatcacgctg caacttatca taattgacaa ttacaccatc
    14461 atctaagtct aattcaattc gttttaatgc taagtgaccc aacttctcgt catactcacg
    14521 aacttctttt aattgcttct gaatctttac aatttctttt gtcattgcat ttctttcttt
    14581 tgggttatca cttgttgaaa tttgttgctg acgcaattcg attcgattgt catacgcttt
    14641 ttgtagttcg tgtaggtatt cagtacgtac ttttcctaat tgatctggtg tatagcgatg
    14701 caagtacatt aacgctttaa agccattttg ttttcctgag tccaattgcc aataaattgg
    14761 tcgattggag tatgttttta aatggtcttt gtaaaaatct tgtacgaagt aacgacgaat
    14821 aatttctcga cttgtccctt tgccacctaa agtgtcagcg ataaactgga gattttcttc
    14881 aagggtttct ttaccaaaag taatctcaac gaaatcaatg aaacgattga caatgtcaat
    14941 ttggctatcc ttgaaatact catcatcggt gatgagtaaa acattatcag tatcaggttt
    15001 aaatttttga tagcgggaag gatcccattc gccgccagcg aagatgagac catcttcgtc
    15061 tagggagtaa cgaccgaaga tacaacctat tgaataagaa ataaaatcct taatttccct
    15121 cgccttatca ggtaaccttg cagagatata ttcatcttga acctcttttg ttaattcttt
    15181 ttcaagagaa taatgattaa tgaatatgtc gttcagttcc tcttcattcg attttagagt
    15241 attaaattga ttaaccaact gcctacttag acagttaaat gcctctgaga gatctttttt
    15301 aaacatataa cttaacaaaa tgtttcttct aaactcgtat gacgtttcaa gagcattata
    15361 gtcttttcta gctatatcga tattttcatc cactttttct cttatttttt ttaattttct
    15421 ctcagatgta actttaagaa aaggtagttt tcccattggt ccttcatggt aatccaaggt
    15481 gggagaaata aaagttaaaa agtgattaac taatttagag tttacatagc caaatatttc
    15541 ttcaaagtca gttatatcct ttgagaacag aacagatcct ttagtttcaa aaattgcctg
    15601 attctgcaat ctaaaagata cttgtccaga tgaaagtgtc gaccaagtaa ttcccttttt
    15661 aaaatagtaa ttaagatttt gtggtctaga ttttaacttc ccatt
//
LOCUS       DACBYO010000069        15627 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.069, whole genome shotgun sequence.
ACCESSION   DACBYO010000069 DACBYO010000000
VERSION     DACBYO010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.069"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(16..648)
                     /locus_tag="IVD26_002075"
     CDS             complement(16..648)
                     /locus_tag="IVD26_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP6080011.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            999..1298
                     /locus_tag="IVD26_002076"
     CDS             999..1298
                     /locus_tag="IVD26_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP6080012.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            1793..3958
                     /gene="acm"
                     /locus_tag="IVD26_002077"
     CDS             1793..3958
                     /gene="acm"
                     /locus_tag="IVD26_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAP6080013.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(4230..4715)
                     /locus_tag="IVD26_002078"
     CDS             complement(4230..4715)
                     /locus_tag="IVD26_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAP6080014.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            5195..5836
                     /locus_tag="IVD26_002079"
     CDS             5195..5836
                     /locus_tag="IVD26_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP6080015.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            5855..6490
                     /locus_tag="IVD26_002080"
     CDS             5855..6490
                     /locus_tag="IVD26_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP6080016.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            6508..7323
                     /locus_tag="IVD26_002081"
     CDS             6508..7323
                     /locus_tag="IVD26_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6080017.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            7642..9078
                     /locus_tag="IVD26_002082"
     CDS             7642..9078
                     /locus_tag="IVD26_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP6080018.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            9267..11714
                     /locus_tag="IVD26_002083"
     CDS             9267..11714
                     /locus_tag="IVD26_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAP6080019.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            11944..13011
                     /gene="rlmN"
                     /locus_tag="IVD26_002084"
     CDS             11944..13011
                     /gene="rlmN"
                     /locus_tag="IVD26_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAP6080020.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(13204..14307)
                     /locus_tag="IVD26_002085"
     CDS             complement(13204..14307)
                     /locus_tag="IVD26_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP6080021.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            14859..15407
                     /gene="aac(6')"
                     /locus_tag="IVD26_002086"
     CDS             14859..15407
                     /gene="aac(6')"
                     /locus_tag="IVD26_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAP6080022.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         5401 a         2528 c         3214 g         4484 t
ORIGIN      
        1 atatattcat tttgattata ctacttttat ttgtaaaaat tttctagcaa aaccaagtgc
       61 ttgcaactga ttaagcgtac aattttttag atgttccgag cgtacttcaa tcatttcaaa
      121 ggagttgcta cttaaatcga tattttttaa atcagtatca aaaaagctag cattttctaa
      181 atcattagta gaaaacatta ttttagtgag ggaacagtct acaaaatctg cgcttgataa
      241 gacagagtgc tcaaaggtac tttcttttat gtttgaacca gataaattta catagtccat
      301 tttacaattc tcgaataacg tgttcccaat ataactttcc atcaatttag tacctgttaa
      361 tttacaattg acaaatttca cgcgatgcaa catgcttttt gtcaatatac agcctgaaaa
      421 atcacagttt tcgaatatac agtcggtaat ctccattctt tgaaaatcat tggaagcaaa
      481 aaatgcatac ttgaaaatag atttgtaaat aattggatgg cagattattt ggttttcgat
      541 gacctctttt tgtgaaagga tattatacag ttcaaaatct tcgttttcat agatatgaaa
      601 aaaggatcct ttattcaagc ttgcttcatt aactttagga aaaatcatat ttaattacct
      661 ccattttcat aaagtcatat taacaaaagc taaaccaact tacattagca gaaaatgaga
      721 taggttttcg cctttttcga taacgatagt gtcgctatct cttgaaacgt tcttagaatt
      781 gccctgagag acacaaatta ggcgtaattc taataaaaat cttagaataa aaatttttac
      841 tgatttaatt tagaatgttt ttaaaataaa aatcgttgcc ataacagtgt attgaaaggt
      901 tttaacaatc cagtaatgat ttaaaaaaat ctagatgtag cgtatacttt gtttatagaa
      961 tgtagtggga agaaatatat ttttgggagg aaatcgtgat gtctaaaagt gaagaaatag
     1021 aaaacatggt actaaaatta tatgatctcg ttttaaatcc agagatcaaa gaaaaggaac
     1081 gtatactttt gatagacgca aagacaggct tagaaaaagg tcagtattat cctaaagtca
     1141 taaataattt ggaacgtagt ttacgtccgt tagcaatcag gggagaattg tctaaaccag
     1201 tatcaccgtt ttatatggag atatcaacaa taggaaaatt tgaaaaagaa ttaggtcgag
     1261 gaatggcttc ggcaccgatt acttttgggc atttataaaa acgagttatt catctcaatg
     1321 aattaaaaag tatagtcaat ctcataatgc aggctaggtt catttatttg aacagagtct
     1381 gtattttttt attctaaata aagaaacaga tgtttcttta tattgtattt tatcctttaa
     1441 ttaacacaaa aacagctagt ataaactaat aatgttaatt aaaagtgtat tttatgaaac
     1501 tatcgttatt tattaatgtt gcatttttgt aagttaaaaa ttggaaatat agattgaaaa
     1561 aatgaaagca ataagtaaaa taaaatgaat atatgcgaaa aaataattta cattaggaaa
     1621 aaccttgtaa aaacagtttt ttggcatatt tattttttat aaatatttgt aaaataacta
     1681 tcaatttttt agttaaaaga ttggaaatga gtgggggagg aattgaagaa aggatttttg
     1741 agagatgata tagtaggttt tatttttagt taaaataggg gagatagaaa aaatgaaaaa
     1801 gtgtagaaat attattttat caatgttatt tattattact aatataacat cactgattcc
     1861 tgttcatgtc tatgcggatg caggcagaga tatcagcagt aatgtcactt cgttgaccgt
     1921 ggacccaacg aatattacag atggaggaaa cataaaagta aaattctcgt ttgacgaaaa
     1981 aaaacaaaat atccaaccag gtgattatct ttggatcaat tggccaagtg aaggaaatat
     2041 tcgcggtgaa ggattccaaa aagaaatccc attaatgatt gaaaataaaa atgttggaac
     2101 tttaacggtc agaaaagatt ctgcgcaggt tgtgtttaat gaaaatatta aaaacctaga
     2161 ctcagtagaa ggttgggggc aatttgagat acaggccaga aacgtaaccg ataccggtga
     2221 agaaaatacg ggaccattca ccgtgacgag cggtgataaa acagctactg taaatgtgac
     2281 aaagccagct tctggttctt cttctagcgt tttttattat aaaacaggag acatgctacc
     2341 tgaagatact aagcacattc gatggttttt gaatattaac aataacggca cttatgttga
     2401 acaaccagtt aaaatcagtg atgaaatcca aagtggacaa agattagatc caagtacgtt
     2461 tgaaattaat caaatacact taggtgaaca gaaggtttat agaggagaag agggaatcca
     2521 acaattttta caagatttcc ccagcgctac atttaatttt tcagtaactg ataattacat
     2581 tgaaataact ataccaaaaa actttgtcaa tcttaggaaa ataatggtga gttataagac
     2641 gatcatagaa aacccagaac aaataaattt tgagaatcat tcggaagctt ggtttaaaga
     2701 atttaataaa cctgctgttg atggagaaag tttcaatcat acagttaaaa atatttcagc
     2761 ttctggtgga gtcaacggta cagttagagg cgaattgaag attttcaaat atatcaatga
     2821 cacagagatt ggtatcccaa atgtgacttt cgaattaaga cgagcagatg aacagcctat
     2881 tcaaggacag tctagtatcc tgttgacttc gaatgaacag ggagaagcta gtatcaaagg
     2941 cctgcaagta ggagactatg ttgtaaaaga aaaagaagca cccaattgga ttgattttga
     3001 tccactaagt tcaaatgaac tcaaattctc cataaacgaa aatgatacag agggagtcag
     3061 tttacctatt tataacaaga aaaaggttac gaacatcaca gcaactaaaa tttggaacgg
     3121 tggaaccact ccaagaccga gtatttattt taaattattc agagcaagta caaacaattg
     3181 ggaaccagtt cctgatgcag aaacaaaacg attagacaat ggaataactt cagtgacttg
     3241 ggaagatatc caacagtatg atgatagtgg aaacgaatat acgtttaaag tgcaagaagt
     3301 agatcaaaac ggaaatgatt atgtcccttc aggttatcaa aaaattgaaa acgggctagt
     3361 cgttacaaat gagaataaag aagtcatttc agtctcagga caaaaaacat gggaagacaa
     3421 tgagaaccaa gacggcaaac gaccgacgac gatcacagta aatctattag ccgacggtca
     3481 accgatccaa cacaaagaag taagtgaaaa agatgattgg cgctatcgtt tcacaaatct
     3541 gccaaaatac agagacgggc aagaaatcat ctatactgta acggaagaca acgtgcccga
     3601 atacagtacg acgattgacg ggtataacat caaaaacagt tatacaccgg aaaaaacaaa
     3661 tatatctata ccaggtagcc atataacacc gtggaaaaat tttccagaga agacagagag
     3721 agagaaaatt agaaatctat tctctcaaaa attgcaaata tttgctcata caggagaatc
     3781 cagcgaacaa agaagcaatt atattagtaa gagagctgta cctaaacaga taacaaataa
     3841 atcaaaaagc attcttccta aaacaagtag taaaaaatct agttttgctg taatcattgg
     3901 tttattgata gtaactatct gtgctgggat attcttacaa aaatataaaa aagtttagtt
     3961 agaatataat attttttgtt aaatatgact gaaatcaaaa gaataaaatt ccgatttata
     4021 atcgaaaaaa gaagcatttt tatatatgct tcttttttcg tagaatcaat aaatatggat
     4081 ttggctaact atggaagaat actcgtatta gttttcagcg ttcatactag ttgttacatt
     4141 gtttgattgg ccaaaagaat ttctgatata ttttgtgcta aataaagaaa aagacgcttg
     4201 aattgggaaa taagaaaact actctatcat tacaaatttt cataaactgg cagatgttct
     4261 aagtaaacaa gtatcttttc aaagtcggaa aaatccataa tcaacgtagt ggtattgata
     4321 tttggatgaa agcctacggt atcttgacga tcaatagcag catcgatcac gacttggatt
     4381 tttttctctt tgtcgtgcat caatgctaat ggagtcactg tacctgctgg aacgcctagg
     4441 aggtcaggaa gctgttcttc agaaacaaaa gataagcgct tttcttttaa ttgttcagct
     4501 agttgtttta aatcggcgtg cttttcatca ggcaagatga caagatagat ttgttttcct
     4561 tttcttgatt tcaataatag attttttact tgcggaccag gtagggaaaa agggacattt
     4621 ttgactgacg taatcgcagg atgatcgact ttttgaaaag agatacccag tttttttagt
     4681 agttcataag cttcttgttc ggttgcacga ctcatcgcgc atcaccctcc tttttttatt
     4741 agtgtatcat aaaaaagagt tgacaaatga aaaataatca tgtaaattac acgtaaagtt
     4801 aaaacaaatg acatcgaaaa gaagagtagc cgttaggtgt ttttagagag tctctggttg
     4861 gtggaaagag gcagcagtta accgtgaaac acatcttgga gtcgattttc tgaagcgtat
     4921 agtaggaaaa tccggggagc ccgttacagc tgcggtcgtt gctagatgac cagataaggc
     4981 tggcttttcc gtgaggagtc ggtaaaaaaa ggtggaacca cgtgattaac gtcctttgat
     5041 cttcggatca aaggactttt tgttttcatc tgaacggcaa cgactgtgtg aggttttttc
     5101 tgcaaggaaa aaataaacag aggtggaacc acgtataata cgtcctcttg gcatttgcca
     5161 agaggatttt tttattttaa aggaggaaaa gaagatggag tatttgattg aagttatgcc
     5221 gcaattatta gtaggagcac tcacaacatt gaaattattt ttatttacct tgattggctc
     5281 attaccatta gggattgttt tagcattagg attgtctttg cattttaagc cgctacgcta
     5341 cttgcttcaa acatatgtat gggttatgcg gggaacaccg ctgttgttgc aactgatttt
     5401 tattttttat gggttgccga cgattgggat cgtttttgat cgtttcgaag cagcactcat
     5461 tgcctttatc ttaaactatg cagcttattt tgcagagatc tttcgtggag ggatacaatc
     5521 gattcctcaa ggtcaatatg aagcagcgca agttttgcaa ttaagtccct ttcaaacggt
     5581 gacgaaaatc gtcatcccac aagtgacaaa gattgtttta ccttctgtag ggaatgaagt
     5641 tatcaacttg gtcaaagatt cttccttgat ctatatatta ggtttaggtg acgtaatgcg
     5701 tgctgggaaa atcgcgatgg aacgcgacgc gactttactg cctttgctag gcgtggcaat
     5761 catctatctt acattgactg gtattctaac aatcgtaatg aaacaagttg aaggaaaatt
     5821 aaattattac cgctaactga taggaggaag aaatatgatt gaattgaaga aagtgaacaa
     5881 agcatttggt gaaaaaaaaa taatcaaaga tttgaatcta atcattccag atgggaaaac
     5941 attagctatc gtaggtcctt ccggtggcgg taaaaccacg cttttacgta tcttggctgg
     6001 cttagaaagt tctgacagcg gagaatttta tttagacggt gtaccgttca acccattcga
     6061 gcttaaaatg aaagaacaag ttgtaggagt cgtattccaa gacttccagc tatttccaca
     6121 tctgaatatt tttgaaaaca ttaccttagc accaaaaatg gtattgaaac agacaaaaga
     6181 agaatacacc aaaaaagcag aagaattagc ggcttcatta gggattagtg atttattgaa
     6241 tatctatcct tatcagcttt ctggcggaca aaaacagcgg gtagcgattg ccagagcatt
     6301 ggctatgaat ccacgggtat tggcttatga tgaaccaaca agtgctttag atcctgaatt
     6361 acgccagcaa gtcgagcgtt tgatcctatc attgaaagaa gatggggtaa cccaaattat
     6421 tgtcacccat gatttagtat ttgcagaaaa tgtcggtgat caattactaa aagtttcccc
     6481 aattcattaa gaaaggagaa gatagagatg aaaaaaacca gttttctatt cgctttgatc
     6541 gcaggtcttc ttctttttgc aggctgttcg aacaaaaaaa cttcagcaga taattgggcg
     6601 actatcaacg aagagaaaaa aatcgttata ggtttagacg atacatttgt tcctatggga
     6661 tttagagata aagacgggaa gctcacagga tttgatattg atttagccaa agcagtcttt
     6721 gaacaatatg ggattacggt agactttcag cccattgact ggtcaatgaa ggaatttgaa
     6781 ctgaacaatg gaacgatcga tttgatatgg aacggctatt ccaaaacgcc ggcaagagaa
     6841 aagaaagtgc aatttacaaa accttatatg gaaaacgatc aagtgctgat cacacctaaa
     6901 gaatcaggaa tcacaaactt tggacaaatg aataataaga gattaggtgc gcaaaatggg
     6961 tcatctggtt atgatgtatt tacgaaacaa ccagaagtat taaaagagat agtcaaaaac
     7021 caagatgctg ttttgtatga tagttttaat gaagcattga tcgatctgaa aagcagacgg
     7081 gtcgatggtc tgctgatgga taaagtatac gcagactatt atttgaaaca aagaaacgaa
     7141 ctagaagact tcaacataac aaaaggttct tatgagagtg aggattttgc agttggtgca
     7201 cgcaagtcag atagtacatt agtgaaaaaa atcaatgaag ccctagatca actagagaaa
     7261 acaggtgaat tccaaaaaat atccgataaa tggtttggcg aagatgttac gccgagaaat
     7321 taacaaatag gggactgtga caaaagacgt gtcacagtcc ctttttccga ataaacagtg
     7381 ttctcctgcc aactccttgt gactcggagc tgaatggcag gctcacaacc tcttggtaaa
     7441 cggtgttcaa aagccagttt ttcggtatta agccaaattt atgcaaaaat gtagaaagcc
     7501 attttcacaa aatttttctt actactcgaa actaagcgac tttttcacaa cctcctttac
     7561 ataattttat tttgttgtgg aaggggtttc gtgttattct aaaagaggaa cgattgaagg
     7621 ttataggaaa ggaagagatg aatggaacac aaagaactta cctcatttcc aaaagatttt
     7681 ctgtggggct ctgcttctgc agcgtatcaa gtagaaggag cttggcaaga agatgggaaa
     7741 ggagaatcag tctgggatcg atttgtacgg atacctggaa agacatttaa aggaacgaac
     7801 ggtgatttgg cagtagacca ctatcatcgt tataaagaag atattgcttt aatgaaagaa
     7861 caaggtctga aagcttaccg cttctctgta gcttggacac ggatttttcc taatggacga
     7921 ggagaagtca atcaagctgg gctcgctttt tatgagagat tgatcgacga attgattgaa
     7981 aacgatattg aacctatgtt gactttatat cattgggatc ttccacaagc attgcaagat
     8041 gaatataatg gttgggaatc acgtcagatc attgaagatt tcactcatta tgcagaaaca
     8101 ttatttgagg cattccgcgg gaaagtccat tactggatta gtttgaatga acaaaatatc
     8161 ttcacttcat taggttattt gttagcagca catccgccag gtgtgacaga cccgaaacga
     8221 atgtatgaag ttaaccatat tgctaattta gcaaatgcat ctgtcatcaa taaatttcac
     8281 gagttagaaa tgcctggaaa aatcggacca agctttgcgt atacgccaaa ttatccaatt
     8341 gacagtaatc ctgaaaatgt tctggctgct gaaaatgcag aagacctgat ggccaattat
     8401 tggatggatg tctatatgtg gggaaaatat ccgattgctg ccatgaggtt cttagaagaa
     8461 aaaggatggg caccaacgat tgaagctggc gatgcagaat tgctagaatc tgctaaacca
     8521 gattttcttg ggatcaatta ctatcaaacg gcgacgaatg cattcaatcc attaaacgga
     8581 gttggtgctg gaaaaatgaa tacgacagga aaaaaaggtt catcagaaga aactggagtt
     8641 cctggaatgt ataaaaaagt tgagaatcca tttgtcgaac gaacaaattg ggactgggag
     8701 attgacccag aaggattaag gatcggactg cgtcgtatca caagccgtta ccgcatgccg
     8761 gtactgatta cggaaaatgg cttaggagag tatgacaagt tgacagaaga taaacaaatc
     8821 catgacgact atcgaatcaa ttacttacaa agccacgtca aagccatcaa agaagcaatt
     8881 tcggatggag cagaagtcct aggctattgc acctggtctt atacagattt gcttagctgg
     8941 ctgaacggtt atcaaaagcg atatggattt gtatatgttg atcaagacga aacacaagaa
     9001 ggatctttgg aacgatataa gaaagacagt tattactggt accaaaaact gattgaagaa
     9061 aatggagaga acctttagtt cacatactta aaacaagaag gtacggctgg atatggccgt
     9121 gccttttctt gataaaatca tttagaaatt aagaaaaact gtaaaataag ctgaaaaatg
     9181 aaagaaagcg tcagttcttt caaacaaaac tttagttccc ttactttttt ttgtataatg
     9241 aaacttgatg aaatgaggga taataaatgg cacaaaagaa acggcctact aaaaaaagga
     9301 aaaagacgaa aaaaacgaaa aagcaaaaac agcagcagga acaaatgctg acgattggtg
     9361 ttgggtttgc cttgatttta tttgctgtct tcggcttttt aaaattaggt tttttaggaa
     9421 tattgattgc aaacggcttt cggatcattg caggaaatac ttaccaaatc ctctgtcttt
     9481 tattagccgt attaggattt tggattgtca ttaagaatac agagttttca attggtaaaa
     9541 accgacgctg gtttggcggc atactctttt atttcggtat cttattattg ttacatgccc
     9601 atttatttgg caaactccat actggggaac caaatatcat ggggacgaca tgggatttgt
     9661 tagccagtga tataaaacaa agtcaagtag acaataacgt tggtggtggg atgattggag
     9721 caatccttta tcattttact tacttcttga ttgcacagcc tggaagttat ttagcagcag
     9781 tgctattact ggcaggagga gcattcctgt tcagtaatct ggaaggctat cagctgttaa
     9841 atggtatcca atcaattgga gaacgagtac aggaattatt ggaaggtgat cctgccaagc
     9901 aagctcgaaa gcaagcggca aaggaagaga gaatgaaaca gcgcgcagaa gcgaaagaag
     9961 caaggcgctt agctgcaaaa gaagctgcag aaaaagaagc tgcagaatat gagaagaaaa
    10021 aagcggtgag ccagcaaagg gaaaatactg ctgatgaatg gcaggaacca gaaaatacag
    10081 agccggagca gctaagtttt gttccaatcg acagttttca agaaaatatc catcctgcga
    10141 atctagagaa accagtacca gatacaccaa aacagaccaa tacagcagaa ggtttttcag
    10201 atgagttgcc agaggatgac ggtacctcat tagaatttga gattgaagca gaacaggaaa
    10261 atcaagacta tgaattaccg acagttgatt tgcttgattc tataccaact gtggatcaaa
    10321 gtgatgagta taaaaaaatt gaaaaaaata tcggcgtatt agaacaaact ttccaaagtt
    10381 tcggtgtcga tgccaaggtc gtcaaagcca gcttaggacc atccgtcaca aaattcgaag
    10441 tccagccggc tgtaggggta aaagtaagta aaattgtgaa cttaacagat gatatcgcgc
    10501 ttgctttagc ggcgaaagat gtccggatgg aagcaccgat tccaggtaaa tcactgattg
    10561 gtattgaagt accaaatgga aagatcagta tggtttcctt tagagaaatc atcgaagcac
    10621 aaccaaacca cccagataaa ttactagaag tacctttagg acgtgatgtt tctggacggg
    10681 tacaaacggc tgatctttcg aagatgcctc acttactcgt ggctggttcg actggtagtg
    10741 ggaagtcagt agcaattaat gggattatca caagtatatt aatgcgtgct aagccccatg
    10801 aagtaaaact gatgatgatc gatccgaaaa tggttgaatt gaatatgtac aacggcatac
    10861 ctcatctgtt gacgccggtc gtgacgaacc ctagaaaagc agcgcaagcc ttacaaaaag
    10921 tagtacaaga aatggaagaa cgatatgaaa aattcgcggc aaccggagta agaaatattt
    10981 ctggttacaa tgaatttgtt caacagaaaa acttggaaaa cggaacgaaa catccaacct
    11041 taccattcat cgtagtgatc gtagatgaat tagctgattt gatgatggta gccagcaatg
    11101 aagttgaaga tgcgattatt cgtttagcgc aaatggctcg ggcagcgggg attcatatga
    11161 tcctagctac tcaacgtcca agtgtggatg ttatcacagg aatcatcaaa gcaaatgtac
    11221 cttccagaat ggcatttgcg gtatcaagcg gtacagattc tcggacgatc attgattcta
    11281 atggggcaga aaagctctta gggcgaggag atatgctatt cttgccaatg ggtgagaata
    11341 aaccgatccg tgtgcaagga gcattcattt ctgaccacga agtagaacgg gtcgttcaat
    11401 ttgttacaga tcagcaagaa gctcattatg aagagaaaat gatgccgaca gatgaagttg
    11461 aaacgacagg tgctccagaa cagccacaag atgagctgtt tgaagaagca aaagcacttg
    11521 tcgttgaaat gcaaacggca agtatttccc ttctccaaag aagatttcgg atcggttaca
    11581 accgagcagc acgtttagta gatgaactgg aagctcatgg agttgttggc ccgtcagaag
    11641 gaagcaagcc tcggaaagta ttcattgagc aggaagaaac atcagaaacg ttgccggacg
    11701 ataatgacat gtaaaacttg tgtgatgaag ggttgaaaaa cgaataacca ataaaaagac
    11761 aaggcatgat gataccaaaa gaaaaaatgg tttttttcca tcttttctaa tacggtatga
    11821 tgtcttgtct ttttagtttt tgtgagatta aagttctatt cgatttattt gtgaagtatt
    11881 gcattaagga aatgaatcat gtatagtatg tagcgaaact ttgagaaaaa gagggaaaat
    11941 actttggaaa aacagtccat ttatggcttg acgaatgaag aattaatcaa ttggtttata
    12001 gaaaacggcg agaaaaaatt ccgagctgcc caagtttggg aatggttgta tcaaaaacgt
    12061 gtaagtaatt tcacagaaat gacgaatcta tcgaaacaat tgatcgaaaa attatcggag
    12121 cattttatca tcaatcctct aaaacagatg gtcgtccaag aagcttcgga tggtacagta
    12181 aaatatttgt ttgaactccc tgataaaaac atgattgaga ctgtactgat gagacaagaa
    12241 tatggcttgt cagtttgtgt gacgacacaa gtaggatgta atatcggctg tacgttttgt
    12301 gcaagcgggc tgctcaaaaa gaaccgtgat ctgactgctg gagaaattgt tgcacagatc
    12361 atgatggtcc aacattattt tgatgagcgc aatcttggcg aacgcgtttc acatgtcgtt
    12421 gtaatgggga tcggtgagcc atttgataat tacgacaatg taatggactt tttgcatatc
    12481 atcaatgatg ccaaaggatt ggcaattggt gctcggcaca ttacagtttc cactagtgga
    12541 ttagcacaca aaatcaagga attcgctaat aacggcttgc aagtcaatct ggctatttcc
    12601 ttgcacgcgc cgaataatga ggtgcgaaca tcgatcatgc ggatcaaccg aagtttccca
    12661 attgagaaat tgatggaagc tgtggatgag tatttagaga aaacaaaccg tcgaatcacg
    12721 tttgaatata tcatgttgaa tcaagtaaat gatagaccag agcatgcgca acaattagca
    12781 gatctattaa aagataagaa aaaattagca tatgtcaact tgattccata taatccagtc
    12841 agtgaacatg atcaatattc tcgcagtcca aaagctgatg tattgagatt ttatgatgta
    12901 ttgaagaaaa acggcgtaaa ctgtgtgata cgtaaagaac atggtacaga tattgatgca
    12961 gcttgcggac aattgcgaag caagcaaatg aaaaaaacag ttgccaaata atcgtatcct
    13021 actcgttttt tcaattacca taaaaggagc agttttctta attaaggaac tgttcaactt
    13081 aaataagaga aaagattcta tagcgaaagc tataaagctt tttttgacaa gaaaaaccct
    13141 catcaagcaa agaaatgtcc tcaatttgat gacagcctgc ttgatggggg ttttagcaat
    13201 tatttaactg attttcttat atccttgctg gctttcttgt gtagcatgat aagtttctac
    13261 gtcaagaatg gcctgtttaa atttttctcg ggtgatttca taaggcacat gtttaatatc
    13321 atttgttgcc atggctttat ctaagattgc ttctaaatcg gtcgtgacat tgagattcat
    13381 gtcggttaac gatactggaa gttggttctt tttcataaac acatagattt tatcaaacaa
    13441 atcgaactgc tgatccatca tcaataaggt cagtacacca taactgacag atgctccgtg
    13501 aaggtatccc tccatttttt ctagaacagt cgtaccgtaa tagaatgagt gtgccatagc
    13561 agaattatag ttattgttaa ctaaaacaga aaccaatccg gtagtaacaa tgatatccga
    13621 aacgacttgt tcaattgcat atgagggacg atcgtcggca ctatctttca atgcttgcgt
    13681 accataagtc aagagacgat caatgcacat ttttccgatt tggattccta atctatccgt
    13741 gtagcctaga tcatcgccac gagcagaaaa agtagattcg acttctttgg ataaagcatc
    13801 gccaatacct gcccataagt atttatcagg tgcttcggca ataattgctg tatcaatgaa
    13861 ggtgtgtaca ggtggttttg aaggaaagaa gagtccgtcc attacgcctt cttcgttata
    13921 gatgacacat accgcagtga cgggcgaaca gttcgaacca atagtgggaa aggtgaagac
    13981 tggtttagct agtttttcac caatgacttt tacagtatcg caagcacggc caccaccgac
    14041 tgcaaacagg acgtctgctt tttggacact ttcatgctgg atcaactgtt caatatttcc
    14101 ataagttgaa ttacccccgt accagagact ggcgacaacc tctatttcct gtgtcaaagc
    14161 tacttttatt ttgttttctg cctttgaaag tgcagtcttc cctccaatca gcactacttt
    14221 tgtcccatat tctttgacga ttccatttgc tttttcatac gcatctgttc caatggtata
    14281 atttggtaag aaaacacttt gactcatatt catttccttc tttcttcgtt gaaacgggtt
    14341 aaaattttaa agagtgatcg atctgactgc ggctgtagat ggagtagagg tgaacctaag
    14401 acaggataag tgatgaataa ggtggcatga acaccttgaa atcatcaata agtatcctaa
    14461 aaacgaacaa gtacaaaaac attgaaaacg acaataatga atttttgttc ctcttagtat
    14521 ttctaccgat tccctttgct tttttgtaat tatctaaaaa ttctaaaaat taagattatt
    14581 atatgaaaac aggttttatt tgtcaattca taattggttt tttttaaagc aaaagataat
    14641 ctatatcatg atgaacaaac agagtttttt cctccaattg atggctttcc tgatctttcc
    14701 tattttgaat aaagtgtttc tgtataattt tttattttat aagtaagata aataatgaaa
    14761 gaatagagat actgattggt agctaaagat ttttgagcga gaacatttcg ttttttcaaa
    14821 aggactgtta gaataagcaa gaacaagggg gaagacgtat gataatcagt gaatttgacc
    14881 gtaataatcc agtattgaaa gatcagcttt ctgatttact gagactgact tggccggaag
    14941 aatatggaga cagctcggca gaagaagtag aagaaatgat gaatccagaa cgaatcgcgg
    15001 tagcagcggt agaccaagat gagttagtag gatttattgg tgcaatccct caatacggta
    15061 tcacaggttg ggaattgcat ccattagttg tagaaagctc ccgacgaaag aaccaaatag
    15121 gtactcgatt agtcaattac ttagaaaaag aagtagcttc cagaggagga atcacgattt
    15181 atttaggtac ggatgattta gaccatggaa caacgttaag tcaaacggac ctgtatgagc
    15241 atacatttga taaagtggct tccatccaga accttcgtga acatccgtat gaattctatg
    15301 aaaaattagg ttataaaatc gtaggtgtct taccaaatgc aaatggctgg gacaaaccgg
    15361 atatttggat ggcaaaaacg attattcctc gaccaaattc tcaataataa aaagaggttg
    15421 tgacagaagt aatcagcttc aagaaataag aaggaattta cgaaaattac ttcttgaatt
    15481 tttgtgaaat tccaacttat ttccgaagaa gctacttttg gaacaccgtg taccagaggt
    15541 tgtgaaaaag tcgcttagtt tcgagtagta agaaaaattt tgtgaaaatg gctttctaca
    15601 tttttgcata aatttggctt aataccg
//
LOCUS       DACBYO010000070        15465 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.070, whole genome shotgun sequence.
ACCESSION   DACBYO010000070 DACBYO010000000
VERSION     DACBYO010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.070"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            47..961
                     /locus_tag="IVD26_002087"
     CDS             47..961
                     /locus_tag="IVD26_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080023.1"
                     /translation="MIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLSFGIG
                     LTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQAPWRF
                     MIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEMNFQG
                     TYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEITFTF
                     KSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSYTFFS
                     KISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(1228..2397)
                     /locus_tag="IVD26_002088"
     CDS             complement(1228..2397)
                     /locus_tag="IVD26_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAP6080024.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            2601..3776
                     /gene="mltG"
                     /locus_tag="IVD26_002089"
     CDS             2601..3776
                     /gene="mltG"
                     /locus_tag="IVD26_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAP6080025.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            3912..4391
                     /gene="greA"
                     /locus_tag="IVD26_002090"
     CDS             3912..4391
                     /gene="greA"
                     /locus_tag="IVD26_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAP6080026.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            4560..5291
                     /locus_tag="IVD26_002091"
     CDS             4560..5291
                     /locus_tag="IVD26_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAP6080027.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYGWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            5288..6355
                     /locus_tag="IVD26_002092"
     CDS             5288..6355
                     /locus_tag="IVD26_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6080028.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            6362..6994
                     /locus_tag="IVD26_002093"
     CDS             6362..6994
                     /locus_tag="IVD26_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6080029.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            7134..7799
                     /locus_tag="IVD26_002094"
     CDS             7134..7799
                     /locus_tag="IVD26_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAP6080030.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            7827..8120
                     /locus_tag="IVD26_002095"
     CDS             7827..8120
                     /locus_tag="IVD26_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAP6080031.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(8188..9135)
                     /locus_tag="IVD26_002096"
     CDS             complement(8188..9135)
                     /locus_tag="IVD26_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAP6080032.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(9313..10116)
                     /locus_tag="IVD26_002097"
     CDS             complement(9313..10116)
                     /locus_tag="IVD26_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAP6080033.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            10262..11176
                     /locus_tag="IVD26_002098"
     CDS             10262..11176
                     /locus_tag="IVD26_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP6080034.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            11224..11694
                     /locus_tag="IVD26_002099"
     CDS             11224..11694
                     /locus_tag="IVD26_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAP6080035.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            11779..12387
                     /locus_tag="IVD26_002100"
     CDS             11779..12387
                     /locus_tag="IVD26_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAP6080036.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            12521..12721
                     /locus_tag="IVD26_002101"
     CDS             12521..12721
                     /locus_tag="IVD26_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP6080037.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            13475..14701
                     /locus_tag="IVD26_002102"
     CDS             13475..14701
                     /locus_tag="IVD26_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAP6080038.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(14809..15279)
                     /locus_tag="IVD26_002103"
     CDS             complement(14809..15279)
                     /locus_tag="IVD26_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAP6080039.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
BASE COUNT         5295 a         2342 c         3030 g         4798 t
ORIGIN      
        1 agctgctata gttactttac ttctttcact agcgtttata ggtcctatga ttgagcagac
       61 attgtatcaa gatctgaata gaccttatgt ggatatatta caaaaaagag caatttatct
      121 gggtaaagag tttttgattg gaagtataga ttcagaatta ctatcatttg gtattggctt
      181 aactttgctt atttgtttaa ttatactaac atttaacttt aaaaaattag gaatcttatc
      241 taaaatcact tatataatgg gtataatatc tattctactt tgtacaaaaa tatttccatg
      301 gtttgcctta caaaatactc ctttaaatat tattcaagct ccttggcgtt ttatgatatt
      361 ttcaacattg ttcatatctt tttcagtatc tctatttatt tctccacagt tggaaaaatt
      421 ttcttataca aggagaagaa attttatact attattaata ttagctattt caattttaaa
      481 ttattcatca gtagttaaca tggtgaaaga aatgaatttt caaggaactt attctaatga
      541 acaaatggaa aataaacttg aagaatttga gaattttgat tatgtaccta taggctataa
      601 aaaagatcaa ttgcttttga aaaaccatca agttacagaa gatggtcaag ttatttatag
      661 tagcttttct ccaaataaag atgaaattac atttacgttt aaatcttcaa aaggcaaaac
      721 aatagtttta cctgtattcc ggtataaagg attaacggtt actgttaatt caaaaaatgc
      781 tacagtacta aaacaaggag gtccttttgt tacagtaaaa agtgaaagtg gaataaataa
      841 agtaacaatc aggtattcat acacattttt ttctaaaatc tcattattta tttctataat
      901 cacgctaatt gttcttcttt tttattgcat aaaattaaaa ataagaacaa gccatgaatg
      961 atttgctagc acatatttta gcaatctaaa gatactattt tagatttaat aggccctttg
     1021 tcaaataatg ttggtaaaga gaaatcttag aataatttgg acagaacaga aagaagaaca
     1081 cctctttctg ttctgtttat ttggaattaa agtctgtagc aaaaattgat ttttagattt
     1141 gtcccacact ctttcctacg tttagtcgag tacttttttt aagcaaatgc tattcaaaga
     1201 agtagtattt gctatctttt catcatatca gctatttgcc aacttagtag ttccttccat
     1261 caggtcatag atttggtttc ttagatcagc agtaggcagt ttgatagttt tgtcagcttt
     1321 tatattgctt tccatgatga tagcatcctg tgaatctttg ctaaatatag cagatgtatc
     1381 aaaagagtcg atatttcctt gcgacaggat ataattatct ccgctatata ccccaccact
     1441 atatggatgt ccattcgcat tttcacgcca taatgagaag agtaagtctt tggaaactag
     1501 ttttccagat aaaacttgtg taaacagcgt atttaaatca tagacggaca tactgatatt
     1561 accagtccct aattcgttat ggatctctgt ttcagattct gtcagtggtt taaagtaatc
     1621 atcctcttta gacatttgat aggatagtgc atgattggat gaatttttga cttggtcata
     1681 aaattttgta tgctgtaatc ctaaaggttc gatgatatca tcggtcaata atttttcata
     1741 cggttgattt gttaatttga tcaaaattcc agtcaatatg gtaaagttca atgaatcata
     1801 atgagaggtc tgataatctg taaattttaa gtgctgaatc gcaaattgaa cgacttcttc
     1861 atcagtcatc ggtatggttg gagaagcagt tcggtgcaag cctgagcgca tatacagcaa
     1921 gtcacggata gtaatttgct ggctgccagc aatttgtgga tagaattgag ccagcttagt
     1981 atctaaagaa aggtgcccac gctcgacttg ttttaaaatc aaaagagtag tcaatgcttt
     2041 ttgaaccgaa ccaatctgat aataaagaga aggatcattt ggttgttgcg tgagtttatt
     2101 cgcatagcca tagccttttt ccatgatgat gcgattattt ttctttacgt aaattgagcc
     2161 aatataatca ttttttctta atagttgatc gattttttca acgagctgtt gttcattggt
     2221 agtcagtatc aacttttttt gagctgattg agcatgggca actatctgag agtgttcatt
     2281 attgtaaaat tgccatccaa gaatagttcc tgtagagaac gcactaaggc taaacaacac
     2341 gacaacgatc attaaaaatg aatattttct ttttttagca tgttttcctt ttttcataat
     2401 agtttattta gtctcctttc ttttttacag aaagaataaa gctaaaatag cttgtatctt
     2461 gataacattt attttaatct tatagtaatg gatttactac ttacattttt gatagaatat
     2521 ttaaataaaa tcattcacgc caattcaaat atcatgtata atgaataaag ttacgaactt
     2581 gatagtaagg aggagttgtt ttgtcaggaa acaaacaaca cccaagtaaa gataaaaaag
     2641 aagccagtaa ggcagctaca gcagatataa tcgacaagcg gagaaatctg cgtaaaaaag
     2701 aagataagat tgtgaggaag atcattttag tgattgctct tacattattg attattggcg
     2761 gatttcttgg atttaccgtg tatcgttatg tagatagcgg gttgaagcct ttagataaat
     2821 cagatgacca attagtccaa gtcgagatcc cgagtggctc ttctaacaag cagattggtg
     2881 agattttgga gaaggacaat attattaaaa gcgggattgt tttcaattat tatacaaaat
     2941 ttaaaaattt aactggcttt caagctggct attatcagtt agcgcctaat atgactcttg
     3001 acgagattgg caaacagttg caagaaggcg gtacttctga gccaacaaaa gttgcagatg
     3061 ggaaaattgc cattccagaa gggtacgata tcgatcagat tgctgaacgg gtagcgaagg
     3121 taactggtaa agacaagaaa gaatttttag atttagtgaa tgatgagact ttctttaacg
     3181 agttgcacca aaaattccca gaactgttgg aaagtgcatc taaagctgag aacacaaaat
     3241 accgtttgga aggttactta ttcccagcca catatgatta ttacacgagt acttcgctta
     3301 aggatctagt gattgaaatg gtgaacaaga cgaatacggt catgcaaaac tattattcag
     3361 ctatcaagca gaaaaatttg actgtacaag aagttttaac tctagcttct ctagttgaaa
     3421 aagaaggcgt aaaagaaaat gatcgtaaaa acattgcaca agtcttcttt aaccgaatca
     3481 aagcaaatat gccacttcag tcagatatct ctgttttata cgcattaggt gaacacaaag
     3541 aattagtgac gtatgaagat acagctgtag attcaccata taatttgtat accaataccg
     3601 gctatggacc tggacctttt gacaatccaa gcgaagaggc aatcaaggca gtattagaac
     3661 cagcagaaaa tgactattat tatttcgtag cagatacgag cactggaaat gtttatttcg
     3721 ctaaaactta tgaagaacat atggaattag tggaaaaata tgtaaataat tcttagaaaa
     3781 acaggctcta gacattgatc atttttagaa aaacatttac atttgaagaa aagcgtggta
     3841 atcttttttg gactatattc ctcaaaagat taccttttgc ggtattttat cgaaaaaagg
     3901 agacgttaca catggtagag aaagtttatc caatgactct agaaggtaaa gaaaaattag
     3961 aaaaagaatt agaagaacta aaaacagtca aacgcggaga aatcattgaa cgaatcaaaa
     4021 ttgcccgcgg tttcggagat ctttccgaaa actctgaata tgaatcagcg aaagatgaac
     4081 aagcatttgt tgaaggaaga atcacaacaa ttgaaaatat gattcgtttt gctcaaatca
     4141 tcgataacga cggtgtagat gcagatgagg tatcaattgg taaaacagtt acattcatcg
     4201 aactaccaga tggagaagaa gaagagtaca cgattgtcgg aagcgctgaa gcagatccgt
     4261 tttctggcaa aatttccaat gattctccta ttgcgcaagc attgattggc aaacgtaaaa
     4321 atgatgaagt aactattgct actccaggtg gcgatatgtt agttaaaatc gtcaaagtag
     4381 aacaagcgta gtctgactga aagatctaga gagttcatct tactgatgat acactctaga
     4441 tctttttctc tttgtgtatt ttagatttca acaaacgatc ttacatctaa agtcctatag
     4501 ccaacagtta aaaaaatagg tatgatgaaa tgagaatgtg tcaggaggga gaaagagcga
     4561 tgaatagttc ttggcgtttt tttgtggtag ttgaagcact actgctgtta tttgctgttt
     4621 ggcaaatcgt aaacaatact ggacttttgc ttttagtgat attcggtatt ttcaatatat
     4681 atctagctat gcgcaaacat cctcgtacta aatttcaaaa ttttcaattg atattaggaa
     4741 gtttggtcat tttttttagc ttagtcaaca gtcctgcttt atggatgatg gctgtatttg
     4801 ccgttttatt tattggtctg aaaggtgtag agatttcagg gatagattta accaaaaatg
     4861 ctttttggcg aaagaaacag atcatgatga tccaaacaga gcaattaaaa acacataata
     4921 atgagcggaa aagacagcaa ttattcggta accaacgtat tggaaacgac gtctatggat
     4981 gggacgatat caacatcgcc gtcatttctg gtgatactat catagatttg ggcaatacgc
     5041 ttttgccaaa agatgataat attgtgattg taagaaaagg gataggcaga acacggatct
     5101 tagtaccttt gggcgtagcc atccgattag agcatgcgac attagtagga aatgtcttgt
     5161 ttgaagaaga gcaattttct ttgaaaaatg aacaaatcaa aatctacagc agtgattatg
     5221 atgaaaaccc tcgtagattg aagattatta ctaatacctt gattggagat gtcgaggtga
     5281 tacgaatatg atgggaaaaa tatccagagc gatgctagct gtttattcgg ggattgcggc
     5341 tttccttatt attctatttt cacttttcac ttatttttat gccagcaatc aaagtcattg
     5401 gtggggagaa ttactgcgtg cacgtttatt atatgttccg cttatcttcc atttgttagc
     5461 catttcctta ggtgtaggat taattgtctt tctattatta tcacttattc aaaagacaaa
     5521 atacgggaaa atcgaagaaa agctgcgtgc actttcttct ggcaattatg aatccaaatt
     5581 gttgcttctt ccgatcccaa gtgcatcgga cgatttatac atcaaagata ttgataagga
     5641 aatcactaag ataaaagaaa aaatgattga agtatctagt gaattacaaa ttgtaacgag
     5701 ccgtccccaa tatgtagatg gacaaaccaa agaagaaatt ttagaattag aaagacatcg
     5761 attagcccgt gagctgcatg attcagtttc gcaacaattg tttgcagcaa tgatgatgat
     5821 gtcggcattg acggagcaag cagaaaaaag cgagacacca gaaatgtttc gcaagcagtt
     5881 gaaaatggta gcagagatca tcaacgcttc ccagtctgag atgcgtgcgc tgcttcttca
     5941 tctacgtcca gtcaatttag aagagaaaag tttaaagcaa ggtatcgagc agttattgaa
     6001 ggaattgcaa aataaaatcc agatttcgct gaaatgggat gtagaagatg taaaactatc
     6061 tagttccatt gaggatcact tgttccgaat cgttcaagaa ttgttatcaa atacattaag
     6121 acatgctaaa gccaatgaat tagaggtata tttgcacaaa atagacaata atcttttgtt
     6181 acgtattatt gacgacggaa cagggtttaa tatgaatgaa acgaaaacgg gaagttatgg
     6241 attgaacaat atcaaagaac gagtagctgg tattggtgga acagtaaaaa tcattagttt
     6301 taaaggtcaa ggtacaagtg tagaaatcaa ggtccctttg atgaaggagg catagataag
     6361 gatgataaaa gttttattag tagatgacca tgaaatggtg cgcttaggcg tctcttttta
     6421 tttatctatt caagaagaca ttgaagtaat tggagaagct gaaaatggac gacaaggcta
     6481 tgagaaggcg atgacacttc gaccggacgt cattttaatg gacttagtca tggaagaaat
     6541 ggatggtatc gaatcaacaa aagcaatctt aaaagattgg ccagaagcta aaatcattat
     6601 cgtaaccagt tttattgatg acgaaaaagt ttatcctgcc attgaagcag gtgcagcagg
     6661 gtatttgttg aagacctcta ccgcacatga aattgctgat gctataaggg caacgcaacg
     6721 tggcgagcga gtattagaac cagaagtgac aacaaaaatg atggaaaaaa tgagtcggcg
     6781 aaatgagcct gtattacatg aagaactaac gaatcgggaa aatgaaattt taatgctgat
     6841 ttctgaagga aaaagtaatc aggaaatagc ggacgaattg tttattacac tgaaaacagt
     6901 aaaaacacat gtttccaata tattggctaa gctagaagtg gaagaccgta cacaagccgc
     6961 tatctatgca ttcaaacatg gtttggtgaa ataaaaacga tgataaagag gataatcaaa
     7021 agctgagaaa ataactatta tttttcttgg cttttttaca ataatgatgc ttgcttttgt
     7081 ttttgtaaag gctttgttat actgagaaaa gaagatacta aaggaggaaa acggtgaaac
     7141 aaaattttgc aattgtaggt cttggacgat ttggcggaag tatctgccga acactgatcg
     7201 aagctggtca agaagtactg gctattgata gtaatgaaga tcgggtcaat gaatatatga
     7261 atatagccac tcatgctgtt gtggcaaatg cacaggatga aatgacactt cgatcattag
     7321 gcataagaaa tttcgatcat gtaattgtcg ctattggaga agatattcaa gccagtatct
     7381 tagttactct gatggtaaag gaaatgggcg taccaaatat tttagcaaaa gcccaaaatg
     7441 agtatcatgc cagagtactt gaaaagatcg gagctgatcg cgtcgtccat cccgagcgag
     7501 acatgggaat aaggattgcg cataatttag tgtcaaagaa tattttagat tacctagagt
     7561 tgtcagataa atattcttta gcagaaatcc gagtctccaa tcctaaattt ttcaacaaaa
     7621 cattagctga attaaatttc aggcaacgtt ttgacttaac agtagtcgcc atacgaagag
     7681 tagatcaaac ggttatcgct tctcctgcag cagatgaata tgttcgtgaa aatgataatc
     7741 tactggttat tggagagaca ggcgatgtgg atattctaga cgataagatg aatcaataga
     7801 aagaaaagag aaagtaggtt gttgggatga aattaacggt aacgccaaaa gcacaaaagt
     7861 ggtttgactc agaaattgat ctgccagaaa cttacggaat acgttttttt ggaaaagtct
     7921 acggcaaaac agaggttcat gatggttttt cgattggaat gtcagttgaa cagccagaac
     7981 atcctgtaaa gaaagtggaa attgatggga cacttttttt tatcgaggaa gcagatgaat
     8041 ggttctttaa aggatatgat ttacttgttg attatgatcc caacctggag gagccaacct
     8101 atcactttaa aaaacaataa aaaaagagag ggtgacacaa tttttgtcac cttctctttt
     8161 ttcttttgaa aatattgttt tcagctatta atatcctgca gacaatttta cttgattggt
     8221 ttgaagctca tgggtggcaa agtagctttt cagattggtt aaaaaaatag ccattaattt
     8281 cttttgaaaa tcaggtgtca aacctgcaat gtgggaagta atcagtacat tgtccatttt
     8341 ccaaagagga tgatcttgtg gaagaggctc ttcctcaaaa acgtctaatg ctgcaaagga
     8401 aagttgctgg ttatttaaag cctgcaccag atcttgtgtc ttaacagaag caccacggcc
     8461 aacattgatg aatacagatt ttggatcaaa gtgttcaaac atatgctgat caaagagccc
     8521 agttgtttcc tccgttagag gtaagatatt gactacgaaa tctacttcag gaagaacttc
     8581 ctttagttga tttaaagaaa aagtcttttc cattccttct gctggatgac cggatgtatt
     8641 gattccatag cagttcatgt ctaatgcttt gcattttttt gcaatcattt ttccaatatg
     8701 gccagttcca atgattagta tttttttccc ttggatagat tggtaatgga ccgatgaacc
     8761 taaccatttc atgtcactct gtgccttttg tgcttgaaaa agaccacgag aatacccaag
     8821 gatgattcct aagacatgct ccgtaatcga ttcactgtgg atgccactac catttgaaag
     8881 taaaatatgt ttctttgaaa aagtctcaag gggtagctga tcaacaccag ctgagataga
     8941 ttggacccat ttcaaggtag aagaggctaa tagtttttct tggtagtctg agttccagcc
     9001 caaactgatc tctacatttt gtagatcctc tggttgtaat tctgttttaa agatataacc
     9061 aggcgctata gtatggattt cttcgataaa ttcatcacga aatggacgat ctgcataaat
     9121 gattctttct gacatagtta atttcccgcc tttctttact ctaagtgtag cgcatacaag
     9181 aagaactttg aagcgccttg cttgtttttt gagaaagaaa tatttttcaa ataaaaaagg
     9241 ggctgtgaca aaaaaatgtc acaacctcta aaagggtcta ttgaagtaga aataacgagt
     9301 tgtctttatt tcttaattga tcgatatttt tgcccatcct ttgacagctt gagcaaaaat
     9361 aaagattcct gcaaaagcaa tgaaggcgct agtgtcaaaa gaaggaagaa agaccatcaa
     9421 gattgttgca attatagtag gcaatgaaat tgaatagatc aatgttttta aacaatcaag
     9481 aaaagtagct tttgttagtc gaaagcgtgc atagagaaaa gcagcaatgt tggtaaatag
     9541 caaagtgatc agcagattca gaaaactagg ataaatagaa aatataaatg tcaggacttt
     9601 tatccaaagt ggtatagatg cttcacttaa aaaagaacgg agctgcttac ctgttaagtt
     9661 ttttaaagat tcattggtgt agggaagttc taattggtta ttgttcaaca aagcagaagt
     9721 cgtgcctgta ttaggaagag ctatgataag tttgtttttt aacatcccga cactaacaaa
     9781 attccccatc aaatcagtag agatgtcctg ttctgttcgt tttccctctg gatcaaatgt
     9841 gaagataatg gagtttgttt ggtaaatgaa tccttctttt tcttcggttt gaagctgccc
     9901 gttttggatt gtaaaatcag gaatgcgagt agcaatcttt tgcccatcca attgaatgtt
     9961 gtttaagact tgaaaaactt gaaaagagat tggcaaagcc ataattatac tcaaaactaa
    10021 aagatagaca atggctttcc aaaatgggac atttctcgcc tcctttaggt ctttgaatcg
    10081 tataaaggaa ctgataatta attgttttgt tgtcataagt actcctcatc tagtagtgtc
    10141 atcacttgca attctagcga agtatcaagt gaaatacaag tgctttaagg aaacagctga
    10201 atgattggtg aaatatcaaa aaaatgttat tcttgtctaa agactatcca atataaataa
    10261 aatggaggaa ggaatagtgc ctacacagcc acagagatca tcaaaaaaac tatttggagt
    10321 agtggttttg aatgcggtga tcactttatc agaatttatt ggagggatta tgtcagggag
    10381 tttgtctctt gtttcagatg ctttccataa ccttagtgat acattggcaa ttattttttc
    10441 ttacggggca caaaaaatgg cccgaaaaga agcaaataaa aaacgtacgt atggctacca
    10501 gcgtttagaa atattgagtg ctttcatcaa ctcattcata ttgatcatat tatccttgtt
    10561 tttaaccgtt gaagcattca agcggttcac ttcaccagaa aagataaata gtcatttgat
    10621 gctaacagta gcagttattg gattgctcgc gaatttgttc tcagtattat tattacgaca
    10681 agaagcagat gaaagtttga atataaaatc tagttatttg catttgttaa gtgatacact
    10741 gtcttcggta agtgtgatta tcggagcaat tttgatccgt tttttcgata tctactggat
    10801 cgatccagtt attacactga tcatttcgat atatatattg atagaagcga taatggtgat
    10861 caaaaaagct gccgctattt tgatacaaag tgcacctgct atcgactatg aaaaaatgga
    10921 acaagaaatt gaagcaatcg atggggtaaa ggatgttcat catgtccata tttggcagta
    10981 tagcgaaaag ataattattt tcgacggaca tattgatttt gaagatcagc tactaagcga
    11041 gattgaaaag atatatcctc gtataatttc tttattaaaa ttaaaatatg gtattacaca
    11101 tgtgacgatc caagcagaga caaaggcaaa ggatcaaaaa aaattaattt ttttaaataa
    11161 agatgaaagt tattgaaata tagagtatga taaataagaa tttttaataa ggtaggttgg
    11221 ctcatgaagc agtatcgaca gttaaaagga tatttagaag caaaaggata ttgggagata
    11281 ctagtctatc tcttttttgg tggtttggct acgattgtaa attttgttag ttttgctctc
    11341 gcacgccaat attttgattt aagtatggcc ttatccaatt ctatttcgtg gttttgttct
    11401 gtattgtttg cttttgtaac gaacaaactt tgggtattcc attcaaaatc accgaatttt
    11461 acacatgcac ttattgaatg cggtaagttc ttcttctacc gtatcctttc ttacggattg
    11521 gacatggggg caatggtatt gttgatcaat gttatgaaca gcaatgagta tgtggcgaaa
    11581 atcatcactc aaattattgt tatccttgcg aactatattt tcagcaagtt gtttattttt
    11641 aaagaaactg aggtttttga agaagaagta ggtcaaagtg aaaaagacga ctaggcataa
    11701 caattgaaga atttccttct ctttgttact ctttgtaatg tagacattat taagaaaaca
    11761 ttgaggagga atttttttat gacttacaca ttaccagatc taccttatgc atatgacgca
    11821 ttggaacctt atattgacga agaaacgatg catctgcatc atgataagca tcacaatact
    11881 tatgtgacga atttaaattc agcaattgag aaatacccag aattaggcga aaaaacaata
    11941 gaagaattat tatctgatat ggacgctatt ccaacagata tcaagacagc tgtacgtaac
    12001 aatggtggcg gacatgctaa ccattcattt ttctgggaaa tcatggcacc aaatgctggt
    12061 ggcgaaccta caggagaaat aaaagaagcg attaatgaag cttttggtga tttttcttct
    12121 tttaaagaag aattcaaaaa agcagccgct ggacgatttg gttctggatg ggcttggctt
    12181 gtaatggaaa atggaaaatt agctattacc tctactgcaa atcaagattc tccattgatg
    12241 gaaggaaaga caccaattct aggtttggac gtttgggaac atgcttatta tttgaaatat
    12301 aaaaatgtcc gaccagatta tattgcagca ttctggaatg ttattaattg ggatgaagta
    12361 aacaaacgtt tcgaagcagc aaaataacca tttcctccgt catatcagtc ttaaaaataa
    12421 tttggaaaat aaaagagcga aagcttgcta gcgttttcta aattgggtat aatgttcttg
    12481 caaggttact tgcaagaact tttttggagg atatacattt atggaacacg gaacggttaa
    12541 atggttcaac aatgaaaaag gatttgggtt tattacagta gacggcggag atgacgtatt
    12601 tgttcatttc tcagcaattc aaggagacgg cttcaagagc ctagaagaag gtcaagaagt
    12661 agaattcacg attgttgaag gtgcacgcgg acctcaagct gctgaagtga ctaaattata
    12721 ataatttgtt gaataaagac acgacttctt agagagtcgt gtctttttgt ctatttatga
    12781 agtttttaga ttttttggct aagtaaatgc atttgttcac ttgacatgtc ctaactaatt
    12841 atcaagcaag gaacattttc ttcgttagta atggatttta aagaaatttc agtttttgga
    12901 tgttgaataa aagaccattt gtgaaaccac tagtatacat actcattacc atgtcaattc
    12961 tattacttta aaagaaaatc gttttacttt gaagaggagc atatctatcc attaaaagat
    13021 gatggtaatg caatcactag ttcgagtcat tttaagagcc atgcagtgag ctggaaataa
    13081 aacgaataga agatgggttt aacaaaagga ccagtcatag gaagaaattg tcgtgaaatc
    13141 gaatgataat ctgaacggta ggcaaagact gttaaaaaga tgggaaaggt atgtgcgatc
    13201 attttactgc acgattattt ggaaaatacc ttgttgttcg ctttttctgg aaaaaataca
    13261 taaaaaaaga taaaacgatt gcgaactgcg tgtattcggt ctttcgatct ttttcacggt
    13321 atggtatgat agttaagaat tttgagaaat tttaaaaaat aataatcgtt acacaaaaat
    13381 gttttttaaa gttttcttat gattaaaaag tgaatttgct gattgaacag ttatatgaga
    13441 caatatttta gaaaatgtga aacagaggtg tattatgaag cgatggcaaa aagttctatt
    13501 aaccttgtta ggggtattcg ttttgctgat tgccggatta tcagcatacg gaatcagatt
    13561 tatgggagaa gcgagccaaa cagtaaacaa aatttctaaa aactctaatc gaatatcctc
    13621 caaacgttct gagagagtaa gcattgatga caaagaacct ttttcggttt tgctattagg
    13681 tttagatacc ggtggattag gaagaacgga acaaggacgt tctgatacga tgatggtagt
    13741 aacagttaat ccgaaacaaa aaaaatcaac gatcatcagt ttggaccgag atatttatac
    13801 gaatatcgta ggttatggaa cggtagataa attaaatcat gcctacgcat ttggtggtgt
    13861 cgaaatggcc atggattcaa ttgagcaact gctcgatatt cctattgatc attatgtaac
    13921 gatcaatttg gatggcatgg aagatttgat caatgcggtc ggtggcatca aagtgaataa
    13981 taaaattgac tttactttgg atggtgtcca tgtaccagta ggtgaacaaa cattgaatgg
    14041 agaaaaaggt ttagcctatt ctcgaatgcg acacgaagat ccagaaggcg atatcggtcg
    14101 acaacgtcgt cagcgggaag tagtgacgaa aatcgtcaat aaagttttaa gtttagatgg
    14161 cgtaagcaat tatagaaaaa ttttaaaagc agttgagaac aatgtgacga cggacttaga
    14221 ttgggatgac atgcttgatg tagcgacgaa ctacaccccg gcgtttgaaa caatcaaaca
    14281 agaccagttg caaggcgaag gacaaatgat caatgatatc tactatcaaa ttttaggaaa
    14341 aaatgatctt ctttcgatcc aaaatgaact gaagaaacaa ttaaatataa aaacaagcga
    14401 tacattacct aatttgaaaa atgagaatgc ttcaatgatg ttctttgatg attcggaaga
    14461 tggcgattcg acaaacggtg atggatcgaa tagtgaaggg tacaccgatt attcttccta
    14521 ttcagaaaac acatatgatc agtaccaaga tccgaatacc tattatcagc aaacagaaga
    14581 tacaagtcag tactatacac caagtcaaga tactcaaagt tatgatcctt acgctggaca
    14641 ggaacaaaat ggttatggtt atgaccagaa taatgagtat ggaacaacaa gtgggtacta
    14701 gaaaaaaata gtttggttaa taaagagtgc cacctaaatt agacaaaaaa tctaacttag
    14761 gtggcacttt ttctatgtgt taaattacag gacgtctctt tttagcgctt agtttaaaaa
    14821 ataaattgaa taattcaata gagttgcgaa tagtacccat aaataataag gaatcatgag
    14881 ccacattgcc aggcgatgat gcagccacaa ctgatacata agcactgaca agaaaataac
    14941 taaaagtgta atatcgattg ctgcaatgaa aatatttctt aaattaaaaa atagagcaga
    15001 ccatataaaa ttaaaaatga actgaatcac aaaaagaccg acaagattgt ttcgctgttt
    15061 tttgttgttg tgattaagta acaaataaag agaaataccc atcaatatat acagtaaggt
    15121 ccacatcggc ccaaatatcc agctaggtgg tgcaaatggt ggaagttgca aagaatagta
    15181 atattttccg ggatttccgc taagcaaccc tgataaaaag cctaatatga caattcctat
    15241 aacacaaacc caaaaacgaa tatcttttat catcttcatt ttactaactc ctttctataa
    15301 tattagttta ccatgaaggc tcacagcaag acctgtattt agtttgtgaa gtaagaaaaa
    15361 aattgataat tgttgttatt aaaaagttga acatttgttt atatgaatga tgtttttgaa
    15421 aaagatcata tgatttgatt ctcatgtttt ctatttgtac ttttc
//
LOCUS       DACBYO010000071        15395 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.071, whole genome shotgun sequence.
ACCESSION   DACBYO010000071 DACBYO010000000
VERSION     DACBYO010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.071"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            185..1183
                     /locus_tag="IVD26_002104"
     CDS             185..1183
                     /locus_tag="IVD26_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP6080040.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="IVD26_002105"
     CDS             1295..1804
                     /locus_tag="IVD26_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAP6080041.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="IVD26_002106"
     CDS             complement(1834..2493)
                     /locus_tag="IVD26_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAP6080042.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="IVD26_002107"
     CDS             complement(2495..3259)
                     /locus_tag="IVD26_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAP6080043.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="IVD26_002108"
     CDS             complement(3267..3944)
                     /locus_tag="IVD26_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAP6080044.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="IVD26_002109"
     CDS             complement(3981..5366)
                     /locus_tag="IVD26_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAP6080045.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="IVD26_002110"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="IVD26_002110"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="IVD26_002111"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="IVD26_002111"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAP6080046.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="IVD26_002112"
     CDS             6305..7162
                     /locus_tag="IVD26_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAP6080047.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="IVD26_002113"
     CDS             complement(7243..7578)
                     /locus_tag="IVD26_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080048.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="IVD26_002114"
     CDS             complement(7645..9015)
                     /locus_tag="IVD26_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAP6080049.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="IVD26_002115"
     CDS             complement(9093..9629)
                     /locus_tag="IVD26_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6080050.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9938..11419
                     /locus_tag="IVD26_002116"
     CDS             9938..11419
                     /locus_tag="IVD26_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP6080051.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(11522..12229)
                     /locus_tag="IVD26_002117"
     CDS             complement(11522..12229)
                     /locus_tag="IVD26_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAP6080052.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(12308..12646)
                     /locus_tag="IVD26_002118"
     CDS             complement(12308..12646)
                     /locus_tag="IVD26_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAP6080053.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(12757..13719)
                     /locus_tag="IVD26_002119"
     CDS             complement(12757..13719)
                     /locus_tag="IVD26_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAP6080054.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(13734..15065)
                     /locus_tag="IVD26_002120"
     CDS             complement(13734..15065)
                     /locus_tag="IVD26_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP6080055.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(15073..>15395)
                     /locus_tag="IVD26_002121"
     CDS             complement(15073..>15395)
                     /locus_tag="IVD26_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="catalyzes the opening and hydrolysis of the
                     beta-lactam ring of beta-lactam antibiotics such as
                     penicillins and cephalosporins; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAP6080056.1"
                     /translation="YMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDVAFLP
                     IGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIMSVSE
                     TLEV"
BASE COUNT         4573 a         3209 c         2561 g         5052 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgata tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcactatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatgctactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag caaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata
     9661 aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca tatttagtta
     9721 tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca aaatacccta
     9781 ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta tataaaaaag
     9841 aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac agtttttgtc
     9901 taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag caagaaaaaa
     9961 agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac aagaattatc
    10021 caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa taaatgtatc
    10081 actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag gagagatcca
    10141 aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa aattatgcta
    10201 cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc cacaaactgc
    10261 tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc tcgaaaaact
    10321 gacaaaacag ctcaatcatt ccttaataaa attccattta cggatcctat ctgtaaaaaa
    10381 ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact tttttctttc
    10441 agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg cactaaaaat
    10501 gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata tctacttgct
    10561 gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa cttcttctga
    10621 aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat actttacttc
    10681 tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact ttaattattt
    10741 tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga ttggtttttt
    10801 attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga cttacttaac
    10861 tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt attttcttgt
    10921 gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt ctacactttg
    10981 ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga aattaagaga
    11041 aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc aataccttag
    11101 tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca tccatttgca
    11161 gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc agttatttcg
    11221 caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca ttacagatca
    11281 gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc acaatacagt
    11341 gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag gttatgagaa
    11401 caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttattccaaa taaatggtat
    11461 tcaatcagct aactctcggt attagctcag atcaaagcgc tgatttcaca acttctttat
    11521 tttaatctct tcggttgccg ccgaacaata agatcaagcg caacagctgc aggaatgtcg
    11581 aaagcgctgc tgcaacataa gtcagtgctg ctgcaaataa tacgtgtctt gccatcggta
    11641 cttcttcttc cgtcagtagt ccgccttcac tcaaaatttg gattgctcgc cgagacgcgt
    11701 taaattcgac tggtaatgtc accaattgga aaagtaatgc taaagaaaaa gcgaaaatcc
    11761 cgatattgat taacgtagag ttccagctaa gcaatacacc taccataatc aaggggaacg
    11821 aaatcatcga accaaagtta gctgctggaa caagtgctgc acgaatcttc aatgggacat
    11881 aacccgaagc atcttgtacc gcatgtccgc attcatgagc tgctacacct atcgcagcaa
    11941 ctgaagtaga ctgtgcagtt gcttgagaca aactcaacat cttattacct gaattgtagt
    12001 tatctgtgag atctccggca atttgttgaa caccgacatt atttatctgt tgactttgta
    12061 atatatattg tgctgcttgt gtaccagtca cattgttttt gcttctcact tgatcgtatt
    12121 ttcggaaagt actattgacg tacgctgacg caattccgga aataactaat ccaagaatga
    12181 ccaaaagaaa tgtcggatct aaaaaaccat acattccata accatacatt ttcgtttcac
    12241 tccttttcgt ttactttatt ttatcattag tagtaggaaa agaatgtgaa aagaccttga
    12301 atattcttta attctttttc acaaattccg atttcagttt catcggtcca aatccttcta
    12361 ccttgcaatc gatattatga tcgccttcta ctaaacggat gttcttgact tttgttcctt
    12421 gtttaatggc acctgacgca ccttttactt tcaagtcttt aatcactgtc acgctatcgc
    12481 cctctaacag acggtttcca tttgcatcta ataccactaa tccgtcttct atgacagttt
    12541 cttgttcttc tttgttccat tcgttcccgc attctgggca aatcaacaag cctcgatctt
    12601 catatgtgta ctctgagcca cattctgggc aatttggtaa tgtcatcttc tttctccttt
    12661 aaaatcttta gtgagcacta ttgtaacgga aaaagaagat cttgaaaaga tacatttgtg
    12721 atttttacta caaaaggcac gttttcgaac gaagtatcat tctgtttttc tgctcttata
    12781 cgattggcat atatcttgga tctctttata gatttcctct acttctgcta aatcttttgc
    12841 attcgcacca cttgctaatg gatggcctcc tccatgatgg cgtttagcca attcattgat
    12901 gatcggcccc ttagaacgta aacgtacgcg gtaataccct gaaggctgct gaacaaaaat
    12961 cccccaagcc agcacttcgt caatcactcc aggaagtgaa acgatcgaag ctgtctctga
    13021 atcatcgatt ccatatttat caagaatttc ttgcggaagg attattcttc ctgcaccatt
    13081 ttcatccacc tggatatttt gataaagata accggaaagt ttagcgactt tcatcggcat
    13141 ttgttcaatc tctctgttca aagcacttgc atcaaatgga taatttctca atatcgaagc
    13201 aatctctaat gtacgggacg tcgtggaggg atacaaaaag cgccctgtat ctccgacgat
    13261 tcctgcataa agtaaccgtg cagccttaac gttcatcttt aaagattcag gaaacatcaa
    13321 agcaaattct gcaatcatct cactacagct acttgctttt gtatttaccc acacaagatc
    13381 tccataaggg tcatcattgg gatgatggtc gattttgatc agtttttctg ccaactgata
    13441 tctttgatca ctgattctgg gtgaattagc tgtatcagtc acgatgacta gcgctccttg
    13501 gtagaagaca tcttcaactt cttgcatttc tgctaaaaag cgaagccctt caatcgtttc
    13561 acctacttga cgtatttctt tttctgggaa actttcccgt aatagttcgg ctaatcctac
    13621 ttgtgatcct aatgcatcag gatcagggcg caaatgcctg tggataatga ttttatcgta
    13681 tttttttatt gtatctacta tttcttgctg tactgtcatt tcactcctgc tttctaagaa
    13741 cgttccatta cttgacaaac aacgattgct ttggaaacga tggtgttttc aataaacact
    13801 tcgatatcca gtttagcgga acgtctgccg atttccaata cacgtggacg aatgtctaat
    13861 tcgctttcca attggatcag ccgcaaataa tgtaggttca cttgttcaat caagatattt
    13921 cgtttttggt tcatcaccat tgttttttgt gcgacatcag aaatgatttc gctaagtacg
    13981 ccaaaagaaa tggttccaac gccattgacc atttgtggtg ctactacgaa tttgaactta
    14041 gggttttcca aacgatttcc ttcacggtca gtatcaatcg tatggatatt tccagatatc
    14101 tgatccgaaa tcgtatctgc aatctgcggt tgtcgctgga caagctgcat cgctttcatt
    14161 acatcttgcc gggtaatcaa gccttccaat gtcaagtcat cggaaacgac cggcatgact
    14221 tctagcccat cccagatcat ttgatggcta acagaggcaa tactcattgt tttctttaca
    14281 ctgattggtt ctttcgtcat cacccgatcg atgatctggt ttggcgattt ccctaaaaca
    14341 tcttttgccg taacaatccc catcaaacga tgatggcggt tgacgactgg aaaacgcgaa
    14401 tgctgcgttt cttctgacaa acgctgataa tcagaaatcg tatctgtctg ctgcaaataa
    14461 tgagtctttt cagctggcat atagatatca ctgacaagca tgatatcttt tttgatcaat
    14521 tggtcgctta acgctcggtt gatcatggtt gcgactgtaa atgtatcata agaggtgcgt
    14581 aagatcggca tttcaagatc atcagctagc tttgcaatct cagcagtcgt attgaatcct
    14641 cctgtgatca atactgcggc gccatcttcc aatgctaatt tttggacttc cgcccggttg
    14701 ccgacgatca ttagtgatcc tggcgtaata tagcgttcca tggcatgttt agtcatcgcg
    14761 ccgatgacga atttattcaa gaccttgtct aatcctgccg ccccgcctaa aacgtcccct
    14821 tcaatgatcc tgacgacctc gccaaatgtc aaacgttcaa tatgtttttt taatttgcgt
    14881 tcgatacgga tggtccctac tcgttgaatt gttgaaacta gtccgacatt ttctgcatct
    14941 ttgattgcac ggtacgctgt tccttcactg acattcaatt cttttgcgat gcttcttaca
    15001 gaaattcgat tgccaacagg taaactttca atatattcta aaatcaaatc atgttttgtc
    15061 gccattttct gcctacactt ccagcgtttc cgagacgctc attatttttc cttcactatc
    15121 ttccagtaac tctacaaaag attcgggatc ttgttcaatg acagggaaag tattgtaatg
    15181 gattggaact actttcttgg cacgaattgt ttgcgcagcc tttgctgcat cttctggccc
    15241 catcgtatag ttatcgccaa tcggcaagaa agcgacatca atatcgaatt cttctgcaag
    15301 caatcctaga tcactgaaat aagcagtatc ccctgcatga taaatcgttt ttccttctgc
    15361 ttgaataata attccgctag gctcgcccat atact
//
LOCUS       DACBYO010000072        15271 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.072, whole genome shotgun sequence.
ACCESSION   DACBYO010000072 DACBYO010000000
VERSION     DACBYO010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.072"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(782..1123)
                     /locus_tag="IVD26_002122"
     CDS             complement(782..1123)
                     /locus_tag="IVD26_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP6080057.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(1123..1353)
                     /locus_tag="IVD26_002123"
     CDS             complement(1123..1353)
                     /locus_tag="IVD26_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP6080058.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            1640..1978
                     /locus_tag="IVD26_002124"
     CDS             1640..1978
                     /locus_tag="IVD26_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080059.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(2183..2422)
                     /locus_tag="IVD26_002125"
     CDS             complement(2183..2422)
                     /locus_tag="IVD26_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAP6080060.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(2398..2745)
                     /locus_tag="IVD26_002126"
     CDS             complement(2398..2745)
                     /locus_tag="IVD26_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAP6080061.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(3477..4058)
                     /locus_tag="IVD26_002127"
     CDS             complement(3477..4058)
                     /locus_tag="IVD26_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6080062.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(4241..4867)
                     /locus_tag="IVD26_002128"
     CDS             complement(4241..4867)
                     /locus_tag="IVD26_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP6080063.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(4889..6220)
                     /locus_tag="IVD26_002129"
     CDS             complement(4889..6220)
                     /locus_tag="IVD26_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAP6080064.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(6375..6776)
                     /locus_tag="IVD26_002130"
     CDS             complement(6375..6776)
                     /locus_tag="IVD26_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAP6080065.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(6862..7068)
                     /locus_tag="IVD26_002131"
     CDS             complement(6862..7068)
                     /locus_tag="IVD26_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080066.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(7163..8665)
                     /locus_tag="IVD26_002132"
     CDS             complement(7163..8665)
                     /locus_tag="IVD26_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAP6080067.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(8683..9138)
                     /gene="argR"
                     /locus_tag="IVD26_002133"
     CDS             complement(8683..9138)
                     /gene="argR"
                     /locus_tag="IVD26_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAP6080068.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(9236..9853)
                     /locus_tag="IVD26_002134"
     CDS             complement(9236..9853)
                     /locus_tag="IVD26_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080069.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            10074..11447
                     /locus_tag="IVD26_002135"
     CDS             10074..11447
                     /locus_tag="IVD26_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP6080070.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            11522..12634
                     /locus_tag="IVD26_002136"
     CDS             11522..12634
                     /locus_tag="IVD26_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAP6080071.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(12706..14343)
                     /locus_tag="IVD26_002137"
     CDS             complement(12706..14343)
                     /locus_tag="IVD26_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAP6080072.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(14511..15119)
                     /locus_tag="IVD26_002138"
     CDS             complement(14511..15119)
                     /locus_tag="IVD26_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP6080073.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         4204 a         3136 c         2670 g         5261 t
ORIGIN      
        1 actcaaaata aaaaaaacct tacattatac tggaatgaac tgtattgata gtgtacctaa
       61 aagctctact gacataagat cgtgtaatcg gtaaagtaat tttattaatt atacgggatg
      121 taatcaatta gagaataaac taatcataaa aggtactttt acattcataa ttgtcgcttt
      181 gagattctac tttggttcac tatctgaccc aattgcacat tttcgatcat tacaagtatt
      241 ggtgtcgtta gaacaactaa ataaaaacta gcggtagatt tttcagaatc tatgctaatt
      301 tctgtatgga tgttccagtg atggcaaatt tctcttttca ttgtttttct tgtcgcatga
      361 tatgcctttt tgtgttattc agttaaacta tagaaattct ttcctagaca gatcttgatc
      421 ccaaatttta cgtttttgag catcgatata gtttaaaatg acattactca tatctaaaga
      481 gtttagattt tttaggacta aaactgtcag ttgttctttt tcttctttct gttaaagtat
      541 tgtcgcgact tttcgtatac gttaagatat gtcgtgaaaa aacaagtttt gtgacacaaa
      601 aaaacgaatg acttgaggaa atcacctcaa tcattcgttt aaaatgctat atattcttta
      661 gtttaagata cggaaattaa tgccatcgac cacactagta gaatgaacga catttacttg
      721 gccttttttt aatttcgtta tgtttagcat ataaaaatat tatagagttt acttacaatg
      781 cttaaaacat atactgtata atctgatcaa ttttagccat gtcttgcaat ggtaagtttt
      841 ctattttttt gagttttcgt tccttaaaat caagagattt taattgtgta ataattactt
      901 gtccttttat atctagctct tcaggtaatg agtaacgtgt cggtaaattc tttatagtgg
      961 aagtaattgg acatatgacc gaaaacattg ttttacggtt aaattcataa cgagagacga
     1021 ctagtcctgg tcgtcttttt tgaatttctt ttcctacgga gggatcaaaa tcaatccata
     1081 caatatcacc ttttttagga atataaattc tttcttctga cactataaaa tttctctccc
     1141 ttcaggagtt aaatcttccc attcgtcttt ctcataatac tcggcctctt ccccaccact
     1201 aaatggatct tcaatttttg gaactaacgt aattgttcca tcatcagaat acacaacgat
     1261 atattcttgg ttttctgaag gtttctttcc gttatcagaa ggtaaagtta ccactacaga
     1321 acttccttgt aatctagatt ttgtaacaag cattatcatc actcccttaa taaaagtata
     1381 ctatataaca ctaagtaacg caaaattccc ctttgtaaac tatctagaaa attgttttgt
     1441 ttaaagtata tcttattgga tataaataga aataaattgt agccagttca ttttttcttt
     1501 aactaaaaaa ataatccaag aaacattgaa cctatggatc caaaagctac ccaaatacta
     1561 tagctaaccc cccgctacct tcaattttgc agataaaacg ctttgggaga aaatttcaaa
     1621 gacaacaggc catcctatca tgcccgatta taaacaaaaa gctggctatt ccttttgctc
     1681 tgacaaattt caattgggaa agttcacgaa actagcaggt gaagaagttt caactgttcg
     1741 gatcaaagaa tgcccgcttc aaatagaaac attggttcaa cgaatttcaa ctagacaaga
     1801 ctttgctatt gtagaacgtg agatcgtagc tatttttgta gaagaaggga ttttacatga
     1861 tccaactcat atcaatgtgg ataaatggca acctcttatc tataaattca gagaatatac
     1921 aactgccaac cagtcgttaa ctttgaattt tagattccaa gaattcaaag agtcataatg
     1981 ataaacatcg ttaggtataa ataaaaaaga ctcgcagcac gagtaaaaaa caaatagaag
     2041 ctatacatta gaaaggtcga ctgtgaccct atagatgcag tatatgcagc ttatgagcat
     2101 ttcttctgtt ctctttgttt ttgggatctg tgctgaagtc tttttcgttt tttgccgctc
     2161 tttctttgaa aaatcgatta tgttatacct tctccattac taattcaggc atctgctgag
     2221 taatgatttt tcgcgcaaaa gaaatatctg ttacccaagg ttcgatttgt tcttcagtca
     2281 agacaagcgg cattcggtca tggattggtg cgactgtgcg gttaggttca gtagtcatta
     2341 tgattgattc tgccattttt tcatcctgat ggctacgata aaaaccgcca atatacacta
     2401 ttttttcctt atttgaaaac ataaatttgt ctttttcttc attccactca ttgggaaaac
     2461 acaacgattt tgcaaaaatg gttgatgaaa ggtctttttt tcttctactg tctctgcacg
     2521 ggcattaatc atcaattgtc cttttttaaa tccggtaaat ccccacttca tgatttccgg
     2581 agtgaggatg ttttcttcct cttttcttaa cgtcacaaca agatttgacg gaaaaacttc
     2641 tccagctgct aattctgctg cctgcttcgg ttgtttcgtc tgggcttctc gataataatt
     2701 ctgaaggagc tctgactcta gatcaaaaaa ataacgacca cacatcctaa tccctcccaa
     2761 tctttttttc tatcatacac tgcaacaaga agttcgcacc aacaaaacgc tttcaatttt
     2821 tgtagaacta aaaaagttgt gacaagtgac aaactctcca gtgaatggta ttctcctgcc
     2881 aactcctcgg tcacaagtca caatattcaa caaacatgag aagctgcttt ttgaaattgt
     2941 tccttgtgac tcggagtgaa acggcaggct tacgacctct gggtaaacgg tgttcaaaag
     3001 ccagtttctc ggtattaagc caaatttatg caaaaatgta gaaagctatt ttcacaaaat
     3061 ttttcttaat actcgaaact aagcgacttt ttcacaacct cttccttaaa cggtgttcaa
     3121 aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tatgagcagc tatttttatt
     3181 tggctgttct tattacttga tgcagggcag ctttttcaca acctctccac taaacggtgt
     3241 tcaatcagct aaccttcggt attagctcaa aaaacggcaa aatatgagga actattttgc
     3301 cgtttgtttc tctaatactc aggtcaaagc gctgatttca caacctctaa tacacggtgt
     3361 tccagaagta gcttcttcga aaaataagcc gaaatttcac aaaaatttga gaagcaattt
     3421 tcgtaaattc cttcttattt cttgaagctg accacttctg tcacaacctc taattattaa
     3481 agaacctttt gcgaagttaa caatctttct ttgatcaatt gaaaattctg cctaagtagt
     3541 gatagatcct gtgtgacttt caacaataag atacttccct ggatttcagc aatcaacgct
     3601 ttggcttgac ggtctgcttc ttcatcggac agtttttctt cagaaagtgc caggatattt
     3661 tgtttcgtat acttgaccca ttgattgact aattctagta gcaacagacg gtattcttca
     3721 tccactgtac tcaactcaat aatcaaatta cctacaggac agccatgata agtgatctgt
     3781 gtctcatgat cagcgaaaat ccagtccaac atttcttcta atgcttcttc tggctgtttt
     3841 ccagcattta agatgtcttc gaacaattct gtctgccata cgtccatatg cgcatggatc
     3901 accgctagac aaacttcttt ttttgaagaa aagtaataat aaaattgacc ttttcctgta
     3961 tcagaagctg ctagaatatc tcggattgac gtttcatgat agcctttttt ataaataaga
     4021 tctttggtcg cttccaagat cttttccttt gttttcaatg atattctcct ttttcatttc
     4081 tcatagtcct atattataca gtaaattcat cattttttct tcttaatcgt ttaaaaaaga
     4141 ctgtgccaaa ttatctgaca cagccctcac tataaaactg ttctcatata gctagatgtt
     4201 cattgattca agaactgcga ggacaaaagc aattcctatc ttatgatagt tgctctaata
     4261 cttcctctgt tgtcatcact tgatctgcaa taaagccaaa gttcgtcaac gctgcatcca
     4321 ttgcttcttg gccaggagca ccaattgcat ctgtcgctac cacaacattg aatccactct
     4381 ctaccaattc acgcatatgg gaatcgctac acaagtttcc gttcattcca ccaagaatta
     4441 ctgtgtcgat tccatttttt ctcaattgga gcgccaaatc attgctttct ggtccaaaga
     4501 ttttatgagg agagctgatg atcgtatttt catccaaata aggtttcaat tcttcgataa
     4561 aatcggctcc tgaaccttct tccactgatt catattgact ttttctagca aacatctgct
     4621 gctcaagcat catatgttct cctgcaccgc caaattgcca tttatggtca tgtgggtaaa
     4681 aataatgagg agaaataaag agtttgtatc ctttttcttt tgcttgtttt accatttcaa
     4741 tcatattttc gatcgtattg tatttttcta agatatcttt tgtcaaacca aagccaccgc
     4801 ctgctggttt caagaactcg acttgcgggt cagtgagaac tactgctgta tttttattat
     4861 tgaacatggt ggattctcca ttcgttattt attttaatac atcatttaga gcttcactca
     4921 ttgtcggatg agaatagatt tgatctctca ataacgtata aggaagtttt ccattcatag
     4981 ctagcgaaat caagttgatg acttcatgag aatcttccgc atagatactt gcccctagaa
     5041 tcaagtcagt ttcagggtcg actaaaactt tgaatacacc tttaggatct tctaatactt
     5101 gtgctttagg gacaccgctt gtcatatact tgaataattt gtaattgacg ccttgtgctt
     5161 tggcttgttt ttctgttaaa cctacattgg ataaagtcgg agtgataaat acactgtaag
     5221 gcacagcttt ccggttattc gttgttcgtt tattctcgcc cttcaactga tccataatga
     5281 ttcgataatc atctagagag atataagtga actgcaatcc gcctttgacg tctccaatcg
     5341 cccaaatgtt gtctgcatct gtacgaaggt attcatccac agcgattgct ccgcgatctg
     5401 ttagtttaac atctgtattt tctaatccaa gtgatgctgt acttggtttt cttccagttg
     5461 cagccaaaac ttttgacgct tggattgtta cttcttggcc atcttctgta aaggtgacgg
     5521 cagctgttga ttcttggtct gctacttgat ctacagatac acctagatgg aattcgattc
     5581 ccgcatttgt catgtcttct aaaatcattt gcgcgatatc ttcatcttca cgtggaagaa
     5641 attcagaatg ggcatcaaga acgacaactt tagatccgta ttcattgaac attgatgcaa
     5701 attccaagcc aatatatcca gccccgatga tcactaattt ttccggtaat tgttcctgat
     5761 ccatcgcttg cgtagaatca atcaagtagc gacttgtatt caatcctttg attggtaaaa
     5821 tgattggttc agaaccagta ttgatgaaaa tccgttcgcc ttcaacaatc actttttcac
     5881 cattattcgt cacttcgatt tgatggttag aaagaaaacg tgctgtaccg tccatcactg
     5941 tcccagttgc ctcatcgctg atcatatgat aatttttggc gcgaagcatg cccgtcaatt
     6001 tttctttccg agcaacagcc tctgtaaagt cgattcctct ttctccattg aaaatcaatg
     6061 atttagaagg aatacagccg atgttgatac atgttccgcc atacatacgt gttgactttt
     6121 caacgactaa aaccgattca ccttttgaag ctaacgcctt cgctaaagtc ttaccgccct
     6181 ttccaaaacc gatcacaata ttttgatatt tttccatcat ttttccctcg cttctttttt
     6241 acctaccgat tggtacaaaa atatgataac cgataattgt ctattctcca aatcatctgc
     6301 tttatttgtc aaaaaaaacc agacaaaaag cggtcctttc acgtttttag tctggttcga
     6361 tttcctttat tcttctaaac aatcgttact tctacatcga tatttcctct agttgctttg
     6421 gagtaagggc agaattcatg cgcatcttct gcaatttttt gggcttcttc ttcgctgatg
     6481 ccatcgatat gcacttctaa tactacaccg atctgatagc cgccatcatc taaattataa
     6541 agagagacac gtgcttttac tgtggactct gctgtcattc ctgcttcttt gatcatatgt
     6601 tgtaccgccc cattgaaaca agaagcataa cctgctgcaa ataattgttc tggatttgtt
     6661 ccttctgcat ggattcctgg aggagtgatt ttcatatgca tcgagccatt tggtgcctcg
     6721 acttctccat tgcgcccgcc atggttgatc attgctgttt cgtatgcttt tttcattgta
     6781 ctgctccttt cgattgacca tttgctactt ggctataatt atagtgtatg acaagtaagg
     6841 cgctttctac aaaaattctg cttattcgaa taccagaatg ccgtcttcta ctatttttcc
     6901 aaaaaacaaa aaaatactac tcgtgaacaa cagcgtcata tttgttccaa aataaatagc
     6961 aatcttttct acataatctt ttatatgatt gattttaaga tacatatata ccagaaagtt
     7021 gaccccataa accaatactg ttaaaaaaat aaccatattc gttaccattt tttcctcctt
     7081 ttgctggtct ccctaccagc actcgattta accataccac tttttttgcc gtccaagcaa
     7141 ctagcctttc aaaaagactg gtttattctg ctgttaatga ttcaagatca gaaaaatgtc
     7201 cgaataattt tgctaatttt actaacgcca acttgttctt tccgaattca tcattttcta
     7261 tctgtaatac tagtaacggc tcatgtaagc ttaaacggat caaaaaccag ccgtttccgt
     7321 atggctcttc tagatcatat cgaatacctt cttcattttc cgggtcgaag ttcatccctt
     7381 tttcttcttc caacagtcgc ttcatttctt ctaatatctt gtttccttgt tcgcgtggtt
     7441 catcgctgaa caattttaat cggatttctt gtacttctac gggctgtttc aactctttga
     7501 tttgttcatc taatgtgata ccttttcttt ttaattctgg caaaagcatc aggatctttg
     7561 cgatgacata tgcaccatca tccagaaaat agttttcctt gaatgcagcg tgtccgcttg
     7621 tttcgatggc tagctgtgta tctttcccaa gacggttaag ttctaatgct ttattgatta
     7681 catttcgata gccggaaata taacgaactt ggatgcctcc tttttcttca atgaatcttt
     7741 gtagatgaga agaagtaggg gaattcgtca cgattcttgt tcctggatgc tcttttaata
     7801 cgattgtact taatactgcg atcaaattat ttcgattgat cactgttcca gaagcactga
     7861 caactgcaga acgatccaca tctgtatcga aaatgatccc aagatctgct tcatttgcta
     7921 aaacagcctg cttgatactt tccatcgctt ctttattatc aggatttggg atatgattag
     7981 gaaatcggcc atctggttcc aaaaattggg aacctgttga atccgcacct aagctattca
     8041 atactttttc agcaaagaat ccaccagcac catttccggc atcaacaatg attttccaac
     8101 catttagtgg tttgctttct agtgttccaa tccccttttt aatttttgtg actaaatctt
     8161 gcgcataagg tgtcaaaagg tctgcttttt ctacgcttcc agtttgttcg ctttttattt
     8221 tttgctgctg tgataggata aaagcaatat cttctttttc tgctcctcct tctgaggtaa
     8281 agaattttat tccattataa taatagggaa gatggctagc agtcagcata accgcagcat
     8341 cgcacgagaa ctgttcaaat tgagtggaca taaacatagc aggcgtagta gctaattcga
     8401 aatcgatgac atgtatccct tgttctttca gactttggat caacgcctct ttcagtgctg
     8461 gtccgcttat cctactgtca tgaccaatcc caatcgtcca ttttttattt ggatcggttg
     8521 atttcttctt tttctttatc cagtttgcta gtccccagcc gatctttttt accatgtctg
     8581 tcgtcaagtt tacttcatat ccttcaactg gtaatgcgat tcctcgaata tccgatccat
     8641 tttgcagcgc tttcatatct ttcatataaa agtcctcctc atttattccc tcattttttc
     8701 cagcttttct gcaaatcgct gtgcttcttc ttctgagcgg caaataataa tgaatgtatc
     8761 tacaccggcc atcgttccga caacttcagg gtaagccact tcatctagcc aattcgttac
     8821 cacatcggca ccatttcgtt cagtcaatac gataaccatg aactgaacag actggatacg
     8881 caaaacctcg cgtctaattg ctgtacgcaa acgttcttca tttaaagaaa cagatggctg
     8941 gttaaataat gtatagcgta ctattttgtt ttcattttga ctttttacta acttcatttc
     9001 tcgaatgtct cgagaaatcg ttgcttgagt cacatcggcg cctgcttcat gcagccgcgc
     9061 aagcagctct tcctgtgtcc caataggttg ttctgtaatg atctggcgga tcagtgcttg
     9121 tcgctgtttc tttttcatat tagacacctc tcaatgttga ttatagcaaa agataagtaa
     9181 tatttcttca tattttggta ttttttactt ttattttttg ttttcattca ggttgctaac
     9241 ctttttctat tttaacacgc aaaatcgtct tcattttttc aggtgctgat tttcttggat
     9301 cgctgatgta aatctctttg tgttctttag aagctctttc atagccttct tttgcgatga
     9361 atgcttctaa tttctcaaac gttgctggtt cttcggcata gggcccgacg tgtaagattt
     9421 gggcacaaag accttcttcc atctttttga atactacttg ttctttcaag tcttccggaa
     9481 gtttgctaga acgctgaatg gcttcttgtg ctatcgcttc tgtaacaaag tcaggctgtc
     9541 ggatcatcaa ttgataagaa aaatgttctt ttttcatcac tggttcatgc aaatactttt
     9601 cttgcagtcc ccattgtcct tccagtggat agacagtata catctgataa tcaggaatca
     9661 gccaattttt tttaggcgac atgcgtattg catagctgac tgcatataga caggctactc
     9721 ttcgtttaaa gtcttcctga ttcgggtcgc cgatccctct gatgctaaag aatgattttt
     9781 taggaacctc tagtatttgc gggctttttt tcatactata gctcttgtct ttacgccatt
     9841 caattttttc catttttctt cctccgcgaa attccattta gttatttatt atcatacctc
     9901 tttttgagtg acttggctaa tcgtgttgac actatttttc agtttgtgct agaataagtg
     9961 aagtaaataa atcgtacaga taacacgttt cggcgtgtcg agagagaggc ggtttctatt
    10021 tttataatag aaatcactct ctttttttac gaaatttttt agaggtgatg taaatgacaa
    10081 aacaaaaaca gctgctttta gtacctgcag taattgcaac agggatgatg tcttttgcgg
    10141 gcgtattgat cgagacggcc atgaatgtaa ctttcccaac tcttatcaga cagtttgatt
    10201 taacgactgc acaagtccaa tgggtaacaa cgatttatct tttgatgatt tcgatcattg
    10261 ttccgctgtc tacttatttg aatcgcaatt ttagtctcaa aaaactcttt ttagcttcaa
    10321 atctgctttt cttggcaggt ataatgatcg atttcttctc tcctaccttc atggtcctat
    10381 tgtttggtcg attgctccaa ggtgcagcga caggtatcgc tcttccgttg atgttccata
    10441 ttatcttgac atttgccccc ctcaatcgac gaggcgcgat gatgggtgtc ggtactttga
    10501 caacggccat tgctccagca attggcccca cttatggagg cattatgact tcacatttta
    10561 catggaatca tatcttcctg tttcttgtgc ccgttttgtt tctttctttg attatcggct
    10621 ggtttgctat tcccgagatg gcagtacaaa aaagtggtta tttggattgg ataagcgttt
    10681 taggaatttg tcttttgttt agtggaagtc taacattttt gagtacgttg ggaacagttt
    10741 ccagctggat tgctttaatc atcggcggta ttggctggtt ccttttttac tatcgaagta
    10801 aaaaagtgga gcatccactg atccgactgt ctattctttc aaataaaaca ttccgcttgt
    10861 ttttgattgg cttcttagtt tatcagtttt tattacttgg tgtatctttt gtcttgccga
    10921 atttccttca gatcgttcaa ggaagtagtc cttttgtcgc tggattagcg atgcttcccg
    10981 gcgcagcggt tggtgctttg ctttctcctt tttccgggaa aatgctggat caatatggtc
    11041 cgaagaagcc aatttttgct gggctgattc tttctttgat tggttggcta gcattattcc
    11101 tactcatagg acacgcttca gtgggtgtat tgattgcttg tcatgtgttt tatatgatcg
    11161 gtatcggatt atcttacagc aatatgatga ccaccggaat gaatgcactg aatgaagaac
    11221 tacaaggaga cgggaacgca atgttcaata ccttgcagca gttttctggc gctgtggcta
    11281 cttcattagt agcggtcatt atcaattacg tccagcatca tacttcccat aactatgaag
    11341 tgtctactac attaggatca aaagcagcat taggcgtctt gttgctgttg cttctcgtaa
    11401 gctttgctcg attcgcctat tatctgttct ttgctaaaaa agcgtagatt ccatatacgg
    11461 caggtgttgc atctgccgtt tttttgtgtg aaaatggttg tttgtaaaag gaggcttttt
    11521 tatggaaaaa attgccatta tcggtggcgg gatcattggt atgaccctag ccagttactt
    11581 agatacatca aaattcaatg ttgctttatt tgatgaaggg acaggacagg caactaaagc
    11641 tagcgctggg attatctccc cttggttgtc gaaacgcaga aacaaacaat ggtatcgtct
    11701 ggctaaagac ggcgctgctt ttttccctaa acttataaaa gatttccaac ttgatcaaac
    11761 gatttacgca caatcaggga cacttttgct tcgacctgaa aaagatttag ctgaattggc
    11821 tgttcttgcc gagaaacgaa aagaagaagc gccagaaatt ggaaacatcg aatggctttc
    11881 acctgaacag acatctcaag cacttccgtt attgaaacca gcagtttcac tgcgtatcag
    11941 tggtggtggt cgtctggatg gaaaagcata tttagaacat cttggtcagc gtttagcaca
    12001 aaaacaaatg gagcagatcc aggcaaaagt cactttgcat aagaagagcg attcttggct
    12061 catcaaggga ccgtttggag aatacacagc tgatcgtgta attttgacac ctggcccggc
    12121 acttaagcct ttattacaag aattaggcta tgctgcagat atacgtccgc aaaaagggca
    12181 gctcttagca tttcagacat cttataagat gagtcaagac tggcctgttg ctatgcttga
    12241 cggagaagct gatttcattc ctttcatgga tggaaagatc cttttaggtg ctacccatga
    12301 aaacgatcaa ggctgggatt tggctcctac tagcgaagct tataagggat tgactaagag
    12361 tacagaacag ttcttgactg atccagatca gataaaaaac tggccatacg agttccgtgt
    12421 aggtacccgt gcttatacgt cagatttttc cccatttttc ggcgtactgc cagatgatcc
    12481 aagcttactg gctgctagcg gtctaggctc ttctggcttg accacaggtc cttatatcgg
    12541 ctatctatta gccaacttct taaatactgg tcattggcct acggaagatt atcaaaagga
    12601 catctccacc tatattacga aaaatccatc atagaaaaac agctttttca agtaaggatc
    12661 ccgagcgata ttgcgcatgg attacttctt gaaaaagctg ttattttagt tcaatttctg
    12721 aatcaaattc tccaaacttt cttttgcttc atctggcaag agatcttttc ctatctgagc
    12781 ttcaatgaat cgtaaacgaa tatcaagtcg ttgtttcacc agatttttat aggacgtatc
    12841 ctcaaaagaa acaggaaaat ctggtatagg taaatagtgg atgtcttcaa atggaccaaa
    12901 cgacttgaat tctgccgttt gttgcacgat tctttcaacg attgacaatg tcgtttcagg
    12961 tttgattttt ttatcatcga aatatccagt attcaggaca tagcaggctg tttgctgttt
    13021 caaaaacaac tctcgaaaag cttgatagtc ttccctaaga ggatagacac ggaaaggatt
    13081 agcaaatggt tcaatgacta gctcatctag ctgtcttttt gtagtgatat tttccgcgtc
    13141 tgatcgtttt gttgctaatg ttgcaccaaa agacgctgct aaaactgggt cattgatctt
    13201 gataattggc ggaagcgaat catctttcat gatccaaaaa acagcatcga tcttttcgct
    13261 aagatgatcg actcggtcgg gtgtcgcata acgtgatttg actgtccgcc catttccgtt
    13321 tcgtatatct cctgttacta ggactttttc tcctttactt gtacatgtca cgcccacatt
    13381 ctgacaagta aggaaagaag aaatggccgg atcatcagac ggatagtctt gtgttttatc
    13441 aaagtaagaa ggttccaagg cagtagcaaa accatttttt cgagaaataa cgaaagcatc
    13501 gtcatgcaag atcgaaacag agtgaccttc cgtatgtttt gctaaggtaa tcgttgattt
    13561 tccagaaccg gacaacccaa atacagccat cgtataggtc tggtcattac tagcatattg
    13621 tttcatccca ccgtggcagg caataaagcc attgcgattt cccaatgccc aagcaagcgt
    13681 caaagtcgct ttttttaatt ctccaaagta acgtaatcct agcacagccg ctgtattatg
    13741 gagagcatca aacaaaatga gtccatttgg aaatgtttca tgtgtccatt cgggatcaca
    13801 aaagatataa agatctccct catcaaagga aacagacttt tgataagtct ctaagatctt
    13861 cgaattcgct ggctgaaaat tcagcaaata agaatacaaa ttgttctcaa atccttctgg
    13921 aatcagcaaa tgactttgca cagaaaattc ttcagatagg ccaacgatta cttttgtatg
    13981 gtaaaactgg cgcttgcgac tttgatacac agcttctctt aaaattttct cgtatttgct
    14041 ttgttccttg tctaagtcct caaagatccg ccgagcactt gctgttcttc ccacaatgct
    14101 tccatcattg aatactagtg tcctaacatc agctggtaaa tctagttctt cagcatgtga
    14161 gattgttaaa tctgtgatga tcgttcctgg actccctttt gctagttgat aagctgtctt
    14221 cctatcaaaa acttcatgaa cattattacc gtaaaatgtc gtttctacaa tcgatcgaat
    14281 actggataac agtggatttc cacttgtgat ttcgtttaat tcgagactct cttttgtact
    14341 catggctcct cctcattccc taaacaaaaa aacgttttct ttattataca ttattcgagt
    14401 ttttatttgt actgctgcgc tgtgggaagc aaacgagtta tttttcacac aaaaaaaccg
    14461 agaacttgaa taaacaagtt tctcggtttc atcattttcc ttttatcggc ttagtaccag
    14521 ccgtttgcta accagaatgt tttagcagca tcccatgaac cataacgaga tgttacatat
    14581 tgttctgcta cacgttcttg attggcagct gaatagtcgc cgtttaagta tgaagcatct
    14641 aattgataac ggccgatgta acgtccgtta gtagctgtgt atgaaccgcc tgattctttt
    14701 tgtgcgatcc attcttttgc agagcttgaa gttggcgctg ttgcagcagc tggggcagca
    14761 ggagctactt caactgtttc aacaggtgca acgtatgtat gttcttgcgt tgctgtttca
    14821 gttgtagatg ctgtattttc tgttgttttg ttttctgttg ttgctgaaga atcatttgaa
    14881 gttgggattg ttaattgttc accaacataa atgcggttga tgtttgcgat cgaatttttt
    14941 tcagcaattg catcgatcat tgagttgtct cctgcaaatt tttgtgagat cttagataat
    15001 gaatcacctg attttactgt ataaacttca tcagcgtgag catttgtagt tcctacaaac
    15061 attgcagtag caccagcagc aaaagttgta cctaaaacaa ttttcttaaa tgaattcata
    15121 ttaaactcct ttttttctcc gttttttatt ctttcgacgc tattaacttt atcatttaga
    15181 aatatttcat aggtaaaaga aacatgacat ttaatgacaa aataacgaat tatttaatat
    15241 ttgtaacatt taaacaaata tttttttgat a
//
LOCUS       DACBYO010000073        14815 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.073, whole genome shotgun sequence.
ACCESSION   DACBYO010000073 DACBYO010000000
VERSION     DACBYO010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.073"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(296..1024)
                     /locus_tag="IVD26_002139"
     CDS             complement(296..1024)
                     /locus_tag="IVD26_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6080074.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="IVD26_002140"
     CDS             complement(1002..2576)
                     /locus_tag="IVD26_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6080075.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="IVD26_002141"
     CDS             2805..3743
                     /locus_tag="IVD26_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6080076.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="IVD26_002142"
     CDS             3755..4666
                     /locus_tag="IVD26_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6080077.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="IVD26_002143"
     CDS             4690..6162
                     /locus_tag="IVD26_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP6080078.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="IVD26_002144"
     CDS             6213..6824
                     /locus_tag="IVD26_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP6080079.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="IVD26_002145"
     CDS             6854..8767
                     /locus_tag="IVD26_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HAP6080080.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="IVD26_002146"
     CDS             8895..11876
                     /locus_tag="IVD26_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HAP6080081.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="IVD26_002147"
     CDS             11873..13534
                     /locus_tag="IVD26_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HAP6080082.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="IVD26_002148"
     CDS             13574..14506
                     /locus_tag="IVD26_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAP6080083.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4815 a         2334 c         2978 g         4688 t
ORIGIN      
        1 atttaaataa ctacatccat ctattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agcgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagt
//
LOCUS       DACBYO010000074        14432 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.074, whole genome shotgun sequence.
ACCESSION   DACBYO010000074 DACBYO010000000
VERSION     DACBYO010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.074"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(26..601)
                     /locus_tag="IVD26_002149"
     CDS             complement(26..601)
                     /locus_tag="IVD26_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP6080084.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(606..1580)
                     /locus_tag="IVD26_002150"
     CDS             complement(606..1580)
                     /locus_tag="IVD26_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HAP6080085.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1604..1648)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1863..2831
                     /locus_tag="IVD26_002151"
     CDS             1863..2831
                     /locus_tag="IVD26_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6080086.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2928..3221
                     /locus_tag="IVD26_002152"
     CDS             2928..3221
                     /locus_tag="IVD26_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP6080087.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3339..3575
                     /gene="secG"
                     /locus_tag="IVD26_002153"
     CDS             3339..3575
                     /gene="secG"
                     /locus_tag="IVD26_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAP6080088.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3687..4433
                     /locus_tag="IVD26_002154"
     CDS             3687..4433
                     /locus_tag="IVD26_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP6080089.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSLAEQ
                     QLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4436..6793
                     /gene="rnr"
                     /locus_tag="IVD26_002155"
     CDS             4436..6793
                     /gene="rnr"
                     /locus_tag="IVD26_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAP6080090.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6815..7279
                     /gene="smpB"
                     /locus_tag="IVD26_002156"
     CDS             6815..7279
                     /gene="smpB"
                     /locus_tag="IVD26_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAP6080091.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7581..8300
                     /gene="atpB"
                     /locus_tag="IVD26_002157"
     CDS             7581..8300
                     /gene="atpB"
                     /locus_tag="IVD26_002157"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAP6080092.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8353..8568
                     /gene="atpE"
                     /locus_tag="IVD26_002158"
     CDS             8353..8568
                     /gene="atpE"
                     /locus_tag="IVD26_002158"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAP6080093.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8659..9183
                     /gene="atpF"
                     /locus_tag="IVD26_002159"
     CDS             8659..9183
                     /gene="atpF"
                     /locus_tag="IVD26_002159"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAP6080094.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9170..9712
                     /locus_tag="IVD26_002160"
     CDS             9170..9712
                     /locus_tag="IVD26_002160"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAP6080095.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9735..11291
                     /locus_tag="IVD26_002161"
     CDS             9735..11291
                     /locus_tag="IVD26_002161"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAP6080096.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11305..12207
                     /locus_tag="IVD26_002162"
     CDS             11305..12207
                     /locus_tag="IVD26_002162"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAP6080097.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12230..13636
                     /gene="atpD"
                     /locus_tag="IVD26_002163"
     CDS             12230..13636
                     /gene="atpD"
                     /locus_tag="IVD26_002163"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAP6080098.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13650..14072
                     /locus_tag="IVD26_002164"
     CDS             13650..14072
                     /locus_tag="IVD26_002164"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAP6080099.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4771 a         2603 c         3106 g         3952 t
ORIGIN      
        1 attttgctaa tccagctctg tttattcagc ctatttttct ttttgaatat atcaagcgtt
       61 gtggcaacat agtgatgact aatgaaacaa cgacgataga caacaaacga tcaaggtagt
      121 ctgtacctgc ctgtaccaag atcacacttg ttgtctgact taaacctaac ccatgtaata
      181 gctgaacgat catactggat cctgaggagg tgatcccgcc aaataactga acggtaatga
      241 tcgaagaaac gatcgttcca ggtaccgaca aaatcaaagc gagtaataac agtttcaagc
      301 tgtttttatc tttgccgaga tatcttggca aaatcaatcc agcaagcaag cctgtgagaa
      361 tttggattgg cgaataatac agagaaaaaa tatctgtagt cactccactt aaaataccgc
      421 tggacaatcc tgtcagcatt ccaggtacag gcccaagcaa tgcaccagca aaaatcgttc
      481 cgatagaatc gagatagatt ggcaaacgaa gccataaagc aatcgttcct ccaatataat
      541 tgatcccaat acacaaagcc atcactgtaa gtacgcgagt tgccattttg tttttattca
      601 ttttgttagc ccatctttaa cctttccaaa tctttcataa tcgtttcttc ttgtgcattt
      661 aaaagaacgg ttaaaaactt tcggaaaaaa agacgagtat ctacttttgt cataatttta
      721 ctgttagcag gtttctgcca aaattcataa cgatcaacca atgtttgtcc acgacttatt
      781 ccttgagttt ccacagcagt gaagcttttg aaaccttcac agatggcctc ctcgataaaa
      841 taagcaacag ctaacggatc attgatgaca catcctaaaa ttctttcttg tttccagtgg
      901 aagtcaaaat aaaaacgagt gatcgctttt agatactctc cctcttcagg attcatttga
      961 cagcagtatt cgaggatagt cggtgtcaag acgatttctc ttgtcacatc taacccaacc
     1021 atttctatcg tttgtttgag attctcgaat acataagaag ctgcttcagg atcacaccag
     1081 taattgtatt cagcaactgg cgaacagtta ccatggcttt tgtaagttcc acccatcgag
     1141 acaaaacgtt ccatatgttt cccaatattt gggttgactt tcaaagcaga agcgatattg
     1201 gtcaaaggac ccaaagcaat gactgatgta tttgtctttt ctttgaaata atcagccaaa
     1261 aaatcaacgg catggagagg ttctgcctgt tttctcaaga tcatcgggaa atttgtttcc
     1321 cctaaaccat ccataccatg agtgtcttgt gcactgatga aaggttgctt caaaggtttt
     1381 tccattcctt gataaacagg aatgtctaaa cgatcacagc gttccaggca tttcagcaca
     1441 ttctgcgtac ctatatctgc agggacattc ccacaaacta cggtaatagc aactacttcg
     1501 atatcagggg atttgacagc taatgataaa gctaaagtgt cgtcgatccc tggatcgcaa
     1561 tcaataatta cttttcgcat tatttccaat ctcctttctt tagagatact tagtttttta
     1621 ttctgggaag tttccgaacc agtccaagac gagcgtcttg attataatgc acgaaattag
     1681 tatactggct tttattgcga atgtaaatgc tctcttacaa gtaaatctat tgaggagaac
     1741 tttaagtaaa tgatacaatg aaaaagaaat ggaatttacg tgtgccgaaa ataaagaatc
     1801 ctatggatcg gtacattgga taatagatag attatagttt ggcagaaagc ggcgggtgta
     1861 caatggttat tttttatttc attcttattc tgataattat agggatcagt taccattttc
     1921 tttcttattt ttatgcaaag aaattagtaa gagcgggagt acagagagga tatgactggt
     1981 atgaagacac tggtcatcgt ttgatggacc ctgctgcagt cacgtcagta gaaaaaaaac
     2041 gacaaaaatt agaagaagag tgtgaaagct tttgggagca gggaacaccc aaaacaatca
     2101 aaagttatga cgggttgaaa ctagctggtc agatgttcat ccatccaaat aagcagaata
     2161 aatgggtcat ttgcgtacat gattaccgaa gcacagggaa aagagacatg tctcatatag
     2221 gtaaaagata tgcagagaaa ggattcaacg ttcttgtacc tgatttacgt gcgcacggag
     2281 aaagtgaagg agaaatcatc ggaatgggat ggctagatcg gctagattta attgcctgga
     2341 tccaactcat cttagatgaa cagccgaatg cgtccattat tttacacggc ggatcaatgg
     2401 gagcttctac gatcatgatg gcaagtggtg aaaaacttcc atcagcggtc aaaggattta
     2461 ttttagacag cggatatgtt tctgtttatg cagaattccg atatatgtta agtaaaatca
     2521 ctgtctttcc taaaaaaatg gtcatgagat atgcgaatca ttatgcccag aaatacgccg
     2581 gttactcctt aaagcaagca tcagctacga gacagcttgg cagcaatcat ctgcctttat
     2641 tagtcatcca tggtgaaaga gatcattttg tccctacaga agcagcgtac acgattcaaa
     2701 atgctacggc aggggataaa gcactgctgc ttgttccgga agcagaacac ttggaagcat
     2761 cgatgaaaga tccgaaaacc tattggacag tgattttttc atttattgaa caaagaataa
     2821 cgatgaatta attttctctt cttttttgta agtaattcga ggataaataa ttgtttatag
     2881 atcaggagac tgctaaaata aggtaggaat aaaaaaatat cagttatttg aggagtgcgg
     2941 catatggaaa tcaaagaaga aaaaatcgtc ttgctttatt caatgatgaa caacaagaga
     3001 tcggagaaat gacatggtca gatgcgggcc cagacatcat gatcgttgac catacatttg
     3061 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
     3121 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
     3181 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     3241 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     3301 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     3361 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     3421 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     3481 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     3541 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     3601 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     3661 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     3721 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     3781 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     3841 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     3901 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     3961 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     4021 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     4081 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     4141 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     4201 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     4261 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     4321 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     4381 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     4441 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     4501 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     4561 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     4621 agtgaaactt cctttaaaac caatcctgat cgaaggaaca tttcgagcaa atgaacgagg
     4681 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     4741 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     4801 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     4861 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     4921 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     4981 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     5041 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     5101 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     5161 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     5221 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     5281 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     5341 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     5401 tgtatatttg actgatcgag taattccgat gatcccgcaa cgtttatcga atggtatctg
     5461 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     5521 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     5581 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     5641 tcagctcgta cctatgttcc aagaaatggg tgaattgcac cgaatccttg aaacgatgcg
     5701 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     5761 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     5821 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     5881 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     5941 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     6001 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     6061 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     6121 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     6181 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     6241 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     6301 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     6361 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     6421 gggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     6481 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacagaaag tgcgagtaaa
     6541 agtagtcaaa gctgatccag atgaacgagc agtagatttt gaacttgttt ccgcagaaga
     6601 ggttacagcg ttggaacggc caaaaacacg aaatggaaaa tcaggaaaac gcgaaggaaa
     6661 acaagcagga aaacgcccag aaagaaatgg caagaagaac aaacgatata gcgatagtaa
     6721 gcaaacgttc ggtaagaaaa aagggaagaa gccattttac aaaggtgtta aaaagaagaa
     6781 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaattaat
     6841 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     6901 ggtcttgcaa ggaaccgaga tcaagtcgat acgaaacagc cggatcaatc taaaagatgg
     6961 atttattcgc gtccgcaacg gagaagcttt cttgcataat gttcatatca gtccttatga
     7021 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaaaaa
     7081 acaaatcatc cggcttgaaa atgaattgaa aaatactgga atcactgttg ttcctttaaa
     7141 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcgaaag ggaaaaaatc
     7201 ttatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     7261 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     7321 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcat aggttttttc
     7381 ttagatcagg agcaccgtgt ataaagaaaa attcgcttcg tttttgactg aaataaaaaa
     7441 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     7501 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     7561 gggaaaagag gtgaaatgga ttggatgaac gctcgctaac gttccacatt ggaccaattt
     7621 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     7681 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     7741 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     7801 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacatcggtt
     7861 tagtaacaaa aatcgtttta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     7921 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     7981 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     8041 ttccgatgaa actgattgaa gaatttacaa acttattaac acttgcttta cgtctttatg
     8101 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     8161 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     8221 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     8281 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     8341 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     8401 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     8461 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     8521 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     8581 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     8641 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     8701 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     8761 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     8821 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     8881 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     8941 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     9001 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     9061 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     9121 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     9181 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     9241 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     9301 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     9361 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     9421 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     9481 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     9541 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     9601 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     9661 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     9721 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     9781 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     9841 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     9901 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     9961 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
    10021 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
    10081 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
    10141 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
    10201 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
    10261 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
    10321 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
    10381 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
    10441 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
    10501 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
    10561 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
    10621 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
    10681 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
    10741 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
    10801 cggttgatgc cggactatct gtatctcgtg taggaggttc tgcgcaaatc aaagcaatga
    10861 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
    10921 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
    10981 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
    11041 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
    11101 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
    11161 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
    11221 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
    11281 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
    11341 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
    11401 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
    11461 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
    11521 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
    11581 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
    11641 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
    11701 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
    11761 tctgatcagc caagctttga tgaagtccgc aaaattgtaa atatggcaac aactatgttc
    11821 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcgctaact
    11881 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
    11941 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
    12001 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
    12061 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
    12121 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
    12181 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    12241 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    12301 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    12361 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    12421 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    12481 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    12541 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    12601 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    12661 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    12721 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    12781 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    12841 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    12901 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    12961 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    13021 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    13081 attgcaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    13141 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    13201 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    13261 ggcttcttct tcaagtgctt tagcacctga aatcgtggga gaagaacatt ataaagtagc
    13321 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    13381 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    13441 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    13501 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    13561 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    13621 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    13681 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    13741 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    13801 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    13861 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    13921 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    13981 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    14041 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    14101 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    14161 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    14221 tggaacaccg tatatcagag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca
    14281 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    14341 tgaacaccgt ttatttggaa taagggactg cgacaagact tttgtctcag tccctttttt
    14401 tgcatatttt tagcatttat ttcctaaaaa at
//
LOCUS       DACBYO010000075        14266 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.075, whole genome shotgun sequence.
ACCESSION   DACBYO010000075 DACBYO010000000
VERSION     DACBYO010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.075"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(52..1476)
                     /locus_tag="IVD26_002165"
     CDS             complement(52..1476)
                     /locus_tag="IVD26_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP6080100.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGG
                     IKKDIKLRVEDSTLIEQIFNDITK"
     gene            complement(1478..2146)
                     /locus_tag="IVD26_002166"
     CDS             complement(1478..2146)
                     /locus_tag="IVD26_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAP6080101.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(2277..2861)
                     /locus_tag="IVD26_002167"
     CDS             complement(2277..2861)
                     /locus_tag="IVD26_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6080102.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(3196..3426)
                     /locus_tag="IVD26_002168"
     CDS             complement(3196..3426)
                     /locus_tag="IVD26_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAP6080103.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKRF"
     gene            complement(3441..4391)
                     /locus_tag="IVD26_002169"
     CDS             complement(3441..4391)
                     /locus_tag="IVD26_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAP6080104.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(4388..5230)
                     /locus_tag="IVD26_002170"
     CDS             complement(4388..5230)
                     /locus_tag="IVD26_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP6080105.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            complement(5363..6088)
                     /locus_tag="IVD26_002171"
     CDS             complement(5363..6088)
                     /locus_tag="IVD26_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP6080106.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGGTA"
     gene            complement(6549..6863)
                     /locus_tag="IVD26_002172"
     CDS             complement(6549..6863)
                     /locus_tag="IVD26_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP6080107.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
     gene            complement(6879..8474)
                     /locus_tag="IVD26_002173"
     CDS             complement(6879..8474)
                     /locus_tag="IVD26_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HAP6080108.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            complement(8497..9387)
                     /gene="iolE"
                     /locus_tag="IVD26_002174"
     CDS             complement(8497..9387)
                     /gene="iolE"
                     /locus_tag="IVD26_002174"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015076872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HAP6080109.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            complement(9404..10429)
                     /gene="iolG"
                     /locus_tag="IVD26_002175"
     CDS             complement(9404..10429)
                     /gene="iolG"
                     /locus_tag="IVD26_002175"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HAP6080110.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            complement(10453..11460)
                     /locus_tag="IVD26_002176"
     CDS             complement(10453..11460)
                     /locus_tag="IVD26_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6080111.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            complement(11573..12733)
                     /locus_tag="IVD26_002177"
     CDS             complement(11573..12733)
                     /locus_tag="IVD26_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HAP6080112.1"
                     /translation="MNIQLKMPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTG
                     HLQKIKELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTA
                     KVVAVLAANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKM
                     MMKDLVFMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEA
                     MKKILNTLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPH
                     GISNAMLLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLS
                     IPTIRDYGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            complement(12809..14263)
                     /locus_tag="IVD26_002178"
     CDS             complement(12809..14263)
                     /locus_tag="IVD26_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010825391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HAP6080113.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
BASE COUNT         4279 a         3050 c         2287 g         4650 t
ORIGIN      
        1 ctaaaccaat aaaaatataa tcttttgttt tcatatatat tctcctcaat tctatttcgt
       61 tatgtcatta aaaatctgtt ctatcaaagt tgaatcttct actctaagtt ttatatcttt
      121 ttttattcca ccatttttta aataaataat tctattgcat gttttataaa gaaattccgg
      181 atcatgagtg gctataacta ctgcaccctt ttcttttaag tctttaataa ggtcagcaat
      241 cctttccata ttaatataat ccaacccact tgtaggttca tcaaatagaa ataaattagt
      301 ttttgacaat gaagctatag aaaccaataa tctttgtttt tctccaccgg ataaatcaaa
      361 cggtaattga tctttcattt tataaagttc catttttttt aaaatttttt cttgctgatc
      421 tttactaact atttcattcc ccagggctaa ctcgctcctc actgattctg tgaaaaattg
      481 gtaatccatt tcttgcatta ctaaaaacgg cgatgacaaa ttttttttat tttcgattat
      541 ctttcctttg gtagggcgaa taatcttcat gagtattctt agtaaggttg ttttccccac
      601 accgtttttc cctaccaaac caataacatc tccaactttg acatcaaaat ttatgtcttt
      661 tagaatattt tcataagtaa tttcttcaac ttttaataca tctgcactta ccttttcgat
      721 atagggaact tcaatcgaac tattaaaaat gtcaaatttc cttaatgcgt tattgttttc
      781 agtttttaac aactgaatag ttgtagtttt tacagttcta tttttaacaa atagaacttg
      841 atcaattaat tctttcaaat agtaaaaacg atgttcagct ataacaatag taaatccttt
      901 attttttaaa tcacaaagta agtcagcaag tttcttagtc gctttgaagt ccaaatttga
      961 agacggttca tccaatataa ttaatttaga gtttagcgat aaactacatc caatagaaat
     1021 tttctgccgt tcaccacttg atagcgaaaa aatgttttta tctaatatat ttgaaagatc
     1081 taataattca gctaattcat tgattctttt atccatatgc tcttttgtaa atccaaagtt
     1141 ttccatcgaa aatactaact cactcgttgt atttgttgta aagaattgtc ctctaggatc
     1201 ttgacttacg tagccaatat tttttgatat actttcttgt gttaaggatt gtagcgagtt
     1261 attttcaaat aaaatttccc caaccaattt tccgtcataa agtcttggaa taagtccatt
     1321 cattaacttt aatagtgtgg atttcccact cccagaagaa ccagtaatca atgtaagact
     1381 accttttttt attgaaaaat taaggtcaac aagcgcttgt tccttaacat ccttatatga
     1441 aaaagaaaca ttgttaaatt caaacaattc tttcacctca aatcaaaata cttaagaaaa
     1501 aaatagtaac ggaaaacagg atgatatagt ctaataagct catgtttgtt ttatagtaag
     1561 aacttctttt cacaggagat tctatcccct ttgttattgc attagcggtc atttcttcag
     1621 caatcatagt tgcacgtata agaacgggaa ctaacagaaa ttccaaatat tgcagaggct
     1681 gaaaaaaaga caagcgaatg tttctcattt ttaaagattc tttaatcatt cttatttcag
     1741 aacgataagt cggaaagaat ctgatcacta ctgtaatact taacattatt tttttcggta
     1801 aatgtatttt ttctaaagag gataataatt cattgctagt atagacacta accaacaacc
     1861 atgagatcat tacgaccggc aacattcgaa atacaatata taaggatgtc ccaaaaaata
     1921 tagtaaaaaa ctctatcttg atagcatcaa taattttcat tactaaaaac agaactgaat
     1981 aaatcaagat gaaataaata catgtcttta ttttacgaaa catcaatact aaaactgtag
     2041 caataatgaa acaccccact tgaaatatat ttccctttcc taaaaaaata atgaccggaa
     2101 aaaaaatatt taaagtaatc aaggttaacg gattgatttt tgacactctt tcacctccaa
     2161 aaaataagat cgcactgtta tcttaagctg ataaaaatgc accgttattc agataacagt
     2221 gcgatcttat caaaaagcat aactgagaac aattctcaat gcaagctttt ttttaattaa
     2281 ctcagtaatt caatccaccc aggaacagaa aattgataca atcttctggt taatagcata
     2341 gtcttttctt ttgaatagct atgcttcaat atatcataga atgtagcgta gaatgagtaa
     2401 atgtagaagt ggatttcttc ttcattaaag actaaatttt gattgatcat tccgatagtc
     2461 tttaacttat ctagacaaca gactgtcttt tttgtcacaa atgatgtaat tttttcaaca
     2521 atatcttgat atttggttcc agctgattgg aataaaacca aatcgaatat acgtttattc
     2581 tcaaaaatat aattaataaa tggatctaat tcattgaagt tctctctcca acttttctct
     2641 atatctatat tttctaagtt taagaggtat ttggtaaact cttcattata catattaata
     2701 agcgcattaa tatgcggctg aataatttct tcaaataacg cttccttaga agtaaaatgt
     2761 ttataaaaag cacccgtagt tacgcctgcg gtcaagcaca gttgccttat cttagtttgc
     2821 tgaaatccta ctttttcaaa atggcttagt ccactttcta ttaatttttg gtgagttgta
     2881 atataatctc tggtttctat gggtacttcc tcctaataag atgaattaac tatattatct
     2941 tacacaggac ttgaagtttc aatcgttaac gtctattact gaactcattc cttagagcta
     3001 aactaatgag aaagagcaaa ataactgata caaaaagcaa tcctacaaga attaatagac
     3061 tcatctaaat cattcacctt ttctaaaata atccgagaaa gatttaaaaa aattatatcc
     3121 agctattagg ataagtccta tcataatcac tccaatagcc attttcttat cctccctaaa
     3181 aataaagcct tttacttaaa accttttttt gtaatcgtca ataaattttt tccctttatc
     3241 agttaattga aatcctatat ctaaatagtc ctcatatcta agtttagtca gcatctcact
     3301 tacagatgct ggactaacac ttagaacttt tgctaaatca ttatttttta atttcttttt
     3361 tctttttgat aattcctgaa ttgctagtaa ataaattagt atagtagttg ttttaatttg
     3421 taccatacct accctccaaa ttatttcgaa aggccttcag caattttatc caggttccat
     3481 ttcatcatcg catagtaact atcaccatct tgtccttttt ctgcaattga atcagtaaaa
     3541 atcgttgaat agataggaat attggtatct tttgatactg ttttcattgg tctatcgtcc
     3601 acactgcttt ctacgaataa ggagggaact tttgttgtgc gtaatttttc aactaagtgt
     3661 tttatttgat ctggtgttcc ttcttcttca gtgttgattt cccaaatgta agcagaaggc
     3721 acattatacg ctttcgagaa atatttaaag catccttcac ttgtaacaat cattttttta
     3781 tcattcggaa ttgaagcaaa tttagattta gcttctttgt ctagagaatc caatttttca
     3841 atatacttat ctagattttc tttatagaat tttttattat caggatcttt ttccgctaac
     3901 tgtttttcaa tatttttagc gtaaataata ccgttttcta aatttaacca agcatgggga
     3961 tcttccttcc ctttctcact ctgaccctct aagtaaataa catctatgcc atcacttgct
     4021 gcaaaatagt ctttgttttc ctctttgttc gcatttttta ctaattttgt aaaccaagca
     4081 tttcctccag tttccaagtt aacaccgtta taaaaaatca aatctgcttt tgaagttttt
     4141 tgaacatctt caggcaaagg ttcatattcg tggggatctt tcccaatagg tacgatactg
     4201 tgtaaatcaa ttttatcttt tgctatattt tcagtaatat ctgctaaaat cgaattagta
     4261 actactacct ttaatttttc gttcgaagcc actgtatctt tgtctttact atttgttgaa
     4321 catgccccga atataaaaag agcaatcaaa atccccagac ttcccagtac tgctttccat
     4381 tttctcatca taactttctc tccttctttc ttaaaaattt ttgttttggt gagattagaa
     4441 aactaattac aaataagaat gccgctgtta aaacaatact tgatcctgct gctatgttaa
     4501 aactataacc aatgaacaaa cctagcaatg atgagcacgc tccgactgtc gccgaaataa
     4561 atatcatagt ttttaaactg tttgcatata aatatgctgt agcagctggt gtaattaaca
     4621 ttgcaacaat taatatagtt cccacacttt gcatagctgt tactgctact aaagttaata
     4681 gaatcattaa tagataatga taaaaactga cattcatccc cattgctttt gccattaatg
     4741 gatcaaaaga agtgattaat aattctttaa aaaatagaac aactgtaacc aacactaaaa
     4801 cagaaacgcc aattgtaatc cacttatcaa tatcttgtac agctaaaata tttccaaata
     4861 agatatgaaa taaatccgtt gagctatttg caactcctat aaggataact cctaatgcta
     4921 aaaaagaact gaaagtaata ccaattgctg tatctccttt tattacacta ttgcttttta
     4981 taaaagtaat aatgatagaa gctaatagac caaatacaat cgcaccaata aaaaaattaa
     5041 tacctaaaat ataagaaatt gctactcctg gcaaaacagc atgagaaata gcatcaccca
     5101 taagagacat tcctcttaaa ataataaaac aacctactgt tccagaaaca atccctataa
     5161 ctacagatgt aattagagca ttctgtaaaa agtgaaagtc atacagacca ttaataaaat
     5221 tttgaagcat attattcccc ttgtatatta gagttagggt tttaaccttc cggttttgat
     5281 tggataaccc tatgaaccat cgttatttta atttggtatt aactcatttc ttttgagata
     5341 atatatttat tggattgaga ggctaagccg ttcccccctc tccaataaat atagtatctc
     5401 cataggcttt ttttaaattc tcttcattaa atacagattc tacacttccg tgagcaatta
     5461 gatttcgatt caaaagaata atattatcaa aatacttctt taccttgctt aaatcatgat
     5521 gcacaattag cactgttttt ccctgatgtt tcaattcttt taacgtatcc ataattattc
     5581 gttcactaac taagtctatc cctacaaatg gttcatctaa aaatatgaaa tccgcatttt
     5641 gagcaagaca tcttgctaaa agtacacgtt gaaattgtcc tccagataat tctcctattt
     5701 gatgattaga atattttccc atatcgacct tttccaaagc ctttgaaact ctttgccatt
     5761 ctgcattttt aattctttga aaaactttca ttccggcata tgttcccata gatacacatt
     5821 cttttacttt tattggaaaa gtaaaatcaa tatcagcttt ttgctctaca tatgcaatct
     5881 tcaccagttt tttattgata tcttcattat taatggagac ctctccctga tgagggataa
     5941 tatttaacat tgctttaagc aatgtagatt ttccagcacc atttggacca ataatacctg
     6001 ttaaagcacc ttcttgtatt tttaaagaaa tctcgttcaa tgctaaaaaa tcgttataac
     6061 aaacattaag ctttttcact tctaacataa ctttctcctt ctaaatgata atgattatca
     6121 cgatcatatg gtatacaaaa attatatttt agtcaaccct aaattttata atttagattt
     6181 ttttctgttg ttgaagatta ggatgtcaaa attatttgaa actactcgta tagtaaatag
     6241 taagtaattt tcaaaacacg aagaaaaaca aaaagaaaaa aggaaacgcc gaagcatttc
     6301 ctttcagtga tttaatgaga acaacacgat ttgacttaga gtctcaaaaa gtcgaatagg
     6361 tacactcatt taagtgtctc cattcgactt tttggggatg agctggctat tgaggtccgc
     6421 ttaccctatt gaataaatac aagattgggt atttctaata agtccgccct tcatattggg
     6481 gtgatcgggg cgaacatgcc atcttttcat ataccacctc ctcgacactc aataatcaaa
     6541 gattctcgtt aatcttcttc gatgcttgca atgatgtttt caatattcat ataacgaaaa
     6601 tcttcttgtt tgatataaac gatctgagcg gtacattttt cctttttgat gatttctttt
     6661 actttttcct cagaacgtgc gacctgcggc gttaaaagta aaacgtcata gtctttataa
     6721 ttcagttttt cttcaacgtt tcggatcgtt gcataatcta tctcatacga tagatttttg
     6781 gctctgatcg tttcaagcat ttttgatacg agcagcgacg cactgattcc ggtctcgcaa
     6841 ataatcaata gatccttatg cataataccc tcctgttttt agcctgcaaa gccaattggt
     6901 gaaaatgcca cataagttaa aataacaatg actaccaatg ctatagcagt caccttggtg
     6961 tatttccaag gctcgatatc gacctttgta tcgaatgagt tcaacacaaa ttctccatca
     7021 ggtttcaatt tggaaaccac catcaaaatg ataatgtcca gaacgaataa tgccgtcaaa
     7081 acataaagga aatggatatt ttggaaaagc atttttgata gtgcatacaa gacgatatgc
     7141 acggcaatcg tcgtttttgc cccaaaagca gttgcttttt ttgaataaaa ggcaaagaga
     7201 atgatcacga gcagcggcat gttgtatagt ccattgaatt cttgaacgaa ctgatacaat
     7261 ccagccggtg caaaagaaat gaatggcgct acgataatgg agataatccc cacaacgacc
     7321 gttactgttt taccagcacg agcgatttgc ttatcatttg ctttcttatt gataagcggt
     7381 ttataaaaat ccagtgaaaa caaggtcgat gtcgcgttca aagctcccgc aaatgatgat
     7441 aagatcgcgc caaagataac agcggcgaaa ataccaaaga tcattttagg caatacttca
     7501 ctgactaaaa aaggatacgc gttatctgga tttgacatta aactatcgcc aaaaatattg
     7561 cgagcgacga tccctggaaa gacaaggaat aacgcaccta agattttgaa gacgccgact
     7621 aggaaagcgc ccttttgtgc ctcagctaaa ttcttgccgg acaatgcttt ttggacgatc
     7681 atttgattgg tacaccagaa atacagattg ttaaacagca tccctgtaaa tagtgtcggc
     7741 catggaacaa cagccgagtc gatcgatccc acagagttaa gcagccatgg cgtgtttacc
     7801 acaacgtgtt cgatcccgcc aacaaagctg ccgtcaccaa gcttcattaa gcctaaaatt
     7861 gggaccagca gaccacaagc cagcagaccg actccataaa tggagtcact attggcactt
     7921 aacgacaagc cgccgatcag cagatagagg atgccgacaa taccaattgc catcgctaca
     7981 attatgatcg cgacgatcgg ctggacgccc agcagctcat caatatggaa gatcttattg
     8041 aacaccagcg atccagaata aagaaccacg ggtaagaaag aagtcatata ggtcacaata
     8101 aataagatcg aaataattcg tttggtaacc gtatcataac gaatctcgat gaaatctgag
     8161 attgtattga tgccgtattt aaaatatttt ggcaagaata tcacagccaa agctacgatc
     8221 gcaatcgtag cagttacttc ccaggccatt acttccatcc ctgcatgata actttgacca
     8281 ttttgtccga ctatttgttc ggtggacagg ttcgtcatga tgatcgtgcc ggcgattggc
     8341 aaagcagtta agctccgccc tcccatgaag aacccttctg atccagaagt atcgacactt
     8401 ctggatctag aataggcaaa taaccataca cagatgacaa tcactaggaa actgattata
     8461 gaaaaaagat tcatcgtcta gctccttttc aatagattaa agaccggtga cctctcgaat
     8521 gtagcttctg gctttgactg catattcaaa tggattggct ttagccgggt cctgttctgc
     8581 ttcaactacg atccagcctt catagtcgct ggcatggatt gctgtccaga ttggagtgaa
     8641 atcaatcatc ccatcaccag gaaccgtgaa gacgcctttc ttcacgccgt ttaagaagct
     8701 gtctttttcc ttttctactt cttcagccgt ttcttgacga atatctttga aatggatgtg
     8761 tttgatacga tcttgatgac ggttgtaaac cgcgattgga ttttcaccag aaaagaccaa
     8821 atgtcccgta tcgaacaata atttaacttt gtctggatca gtcatttcca ttaaacgatc
     8881 gatttcttcc gtcgtttgaa cgccggtacc catgtgatga tggtaaacga tctccatatc
     8941 cttttcgtgg gccaaatccc ctaatttttc taatccttcc gccagttttt tccactcttc
     9001 atcagtgaaa actggtttat catcaaagac tggcgctgtc ataatccctt ggatactatg
     9061 accctgctca gctactacga tgactttagc gcccatcgca tgtaagaaat cccgatgtgc
     9121 tttgaaggct tcggcagttt cttcaaaagg tttagttgtc agaaacgcac tgaaccatgc
     9181 actggcaacc tttaagccgc gaatattcaa atattgttcc aacacctctg gatcttttgg
     9241 atatttgttg ccaatctctg ttccggtgaa cccagcaagg gccatttcac tgatacattg
     9301 ttcaaaggta ttttcactac caagctcggg catatcatca ttggtccacg cgattggtgc
     9361 gatggctaat tgaatttgtt tggtcatatt ctcacactcc tgcttatttt tttagttgta
     9421 ctaaactctt cgtatcgaat gattcttgac aagccaacgc gatcttagtt gattgcaatc
     9481 catcttctgc attaaccgct ggttgacgtt tttcttgaat acatgagaca aattcttggg
     9541 cttcacgaat gaaggcttct ctgaatcgtt ctgggaagtt ttgtgaacat ggacggatga
     9601 tcccttgatc gttcatgatc gtcacaagat ttttctcagg cgcttgcgct acccgcagca
     9661 ttcctttggt tcccatgatc tctgtttcga catgatagcc atgggctgcg tttctgccgg
     9721 caactagtaa agctattgtt ttatcgctca ggctcatcat tgcggctcca gtttcaagct
     9781 caccagcctg atccaattct ggatacgccg catttttccc aatcgcccac acttgatcga
     9841 cttcttggcc ggtaaaccag cgaaccaaat caatatcatg gatcgccata tctaagaaca
     9901 agccgccgct gtcgttattc atggcaaatt tgacaaagct ttccaagcct tcgctcggat
     9961 cgatcccata acaacgaatc agtgtgattt cgccgatttc gccatcttct accattttct
    10021 tcgcatactg atacgactca tcatagcggc gcatgaagcc taacatgaag acctgttcag
    10081 gatgctcttc gatgactttt tgggtctttt taatatcttc aacttcaagg cctaatggtt
    10141 tttcagtaaa gacatgcttg ccattttcca tcgccaagcg gacttggtca cagtgaaagc
    10201 ctgatggtga aacaataaag actgcatcga tcacggaact tttgaccatt tcttcatagc
    10261 tggaaaaagt atgcttgacg cctaatttct tctgtgcgaa tgctaattct gtttcaacta
    10321 aactgcacgc agccgtaagc tcacaacaac tgacacctgt tgctaaattt tgtgcatgta
    10381 cttttcctaa tcttcctaaa ccgacgatgc ctactctaat gttgttcatg aaatacctcc
    10441 gttttctgag aattactcat tgtatagtgc tggtcgttca tccatttgaa tcattacttt
    10501 tgtttttgtt tcacgagact catgacaagc catcatggtg atcgctgcta catacccatc
    10561 ccaagcggta ggaccgacaa ccgcatcatt tttgatcgaa tcgatccaca gcttgaattc
    10621 ataatcatag gcatccaaaa agcgggtctg ccaatctggt gaaacaggtg tgtaattttt
    10681 ttcttccgat ttaattcgtg tataggctgg gtccgtcatt cctacttctg ccgtttcgaa
    10741 aaccacatca catttaatat cgtagccaaa gcggcaattc acaaagattt ccaaatcaat
    10801 cgttacaccg gattttgttt gaaagatcag cagctgcgga tcatgcaaat cggcatggga
    10861 gttgctggtt tttttcggca agatcatttg aacagattca taatcttcat ttagcaacca
    10921 gcgaagcaca tcaatctcat gaatcgcggt gttgctgatc gccatcggtg ttgtgtagtt
    10981 ttcatctgcg ctaggatttc tatgggcaca atgcatcatt aatgcttctc cgtattgctt
    11041 cgattcgatt gcttctttca gttcaatgta gccgcggtca tagcggcgca tgaagccaac
    11101 ctgaaccaat ttcttcccat aagcaacttc cgcatcaacg atccggcggc agcctgctgc
    11161 atccatcgct aatggctttt cgcagaaaac atatttccca tgcttgattg cttctaacac
    11221 atactgctca tgggtcgggt cccaagaagt cacaacaacg acatccacat cttcagaagc
    11281 gatcaatgct tctccggttt caaagaattt agcatcgaca cgtttggcaa cctctttagc
    11341 agcttttaca ttgatatctg agactgctgt cacataagcc ccttgtgttt tctgattgat
    11401 cctgtcgata tgctcgatgc cgattgcacc tgttccgata acgcctactt ttactctcaa
    11461 ttacttatcc ccctgttctg ttgtttaagc acacatagta tgcgcttaca aaattattcc
    11521 tgtgtagctt ttattcttaa aaggtagagc cctctctttg ctccgccttt tactacccat
    11581 aagcttgtac gtataattcc ttaatttgac tatgactagg caccttttta ttattttgcg
    11641 gacttccgct ggtcaacgca tccgcggcca ttttgtctaa ggctgccata aacgcttgct
    11701 gatcaatacc ataatctcga atcgttggga tcgacagctg ctcacagagc tcttggattt
    11761 ttttaatcag ataatccgca gcctcttcca gcgataaatc ttcggctgcc ggataaataa
    11821 atctggcgat cgtcgctaac tcagtctgaa tagcatcctt tgagaattca aaaaagaccg
    11881 gcaataacat cgcatttgat atcccatgag gaatgtgaaa aagtgccccc accggtcgac
    11941 tcattccatg aatcaatgtg actgacgcat tcgaaaaggc aatccccgcc tccgttgaag
    12001 ctaagctcat ttgttctctg gcttcagtgt cgtcgctatt ttcatatgcc tgagaaagcg
    12061 tgttcaaaat tttcttcatc gcttccagtg aaaatagttg cgttacttca ttggctttga
    12121 ctgaaacata agattccaaa gcgtgacata gcgcatcgac tcccgttgcc gcggttactt
    12181 ttggtggtac agttttcgta aaatcagagt caacgattga gatctgtggc atgaaaacga
    12241 gatccttcat catcattttg actgctgttt ttgtattggt aataactgcc acatcggtta
    12301 cttccgaacc agttccagca gttgttgaca ctgcaatcag cggaatgccc gcttgcagct
    12361 gatcaaaatt tcttgcatga atcgcttcga gacttaattg attagcagcc aaaacggcta
    12421 ccaccttggc tgtatccaga cagctgccgc caccaaaagc aatgatatga tcacattgat
    12481 gcttctgaaa aagcttcagc gcatcataaa cattttcttg cgtcggttcg gcttgaatgt
    12541 ctgtatactc cgctaattga tcatctgttt ttcccaacag ctccttgatc ttttgaagat
    12601 gcccggtctg ttccataacc gtatcactaa tgattaacgg cttgttgcct agttgttctg
    12661 attcttccat aagaaattgg attgttccgc cgccaattct taaattggca ggcattttca
    12721 gttgaatatt cacagaaaaa acctctctct ggcttatagc ctataacaga atcctcgaag
    12781 ctctttaaca gagcttcgaa gcaaatcttt aaatctcact ttgcgcataa cgtgctgtaa
    12841 caactttccg atgggtataa aactcaacac tgtctttgcc attggcatgc aaatcaccaa
    12901 agaaagagtg cttccagcct gaaaaggcaa accaagccat cggtgcaggc accccaagat
    12961 tgacccccag catcccagca tcaacatttt ctctgaagta gcgaatcgct gatgcgttgt
    13021 tggtatacag acacgaacca ttcgcaaatt cagattcatt cgtcagctca acggctgcca
    13081 tcaaatcttt tacccgcacg attgatgcga ccggggcaaa aatctcatcc tgccagatct
    13141 tcatatccat cgtgacatta tcaaaaatcg ttggtccaac aaaatagcct ttttctggaa
    13201 tgttttcgcg accatctagt accagtttcg ctccttcatc gacccctttt tggatatagt
    13261 caaaggtccg ctgctgtgca tcttttcgaa tcactggtcc taaaaagacc ccttcgtcca
    13321 agccattgcc gatcttgatc gcttttgccg cagccttaaa tttttcaaca aactgatccg
    13381 cgatttcctc ttccaaaaca atgacggagg ctgccatgca gcgttcacca gcagaaccaa
    13441 aagctccgcc aataaggtcc ttgactgccc gatcaatatt ggcatctttc agcacaacaa
    13501 catgattttt cgctccagtc aacgcttgta cccgttttag attttttgtt ccttcacggt
    13561 aaacgtattc accgacattt tttgatccta caaagctgat gccttttacc agtggatctt
    13621 gcagcaatgt gttgacaaca tcgtgggcac catagacaac attaaaaaca ccgctaggaa
    13681 agcctgcttt ttcaaccagc tcaacaattt tctccatcaa caatggtgtt ttttctgaag
    13741 gcttcagcac caccgtattt cctgccgcca gagccatcgg gaagatccag aagggcacca
    13801 tcattggaaa attaaacggt gtgatccctc cgattactcc gattgggtaa cgataattcg
    13861 tgatctcaat atcagtcgcc gctgttgata aagaatctcc catcattaaa ttggtgattc
    13921 ccgctgcgtg ctccacattt tcgattcctc gttgaacttc tcccagtgac tcggacaatg
    13981 atttcccatt ttccagcgtg atcaaacgcg ccaattcact tttatgatct gttaaaagct
    14041 gatgcagctt gaacagataa cgtccgcgaa caggaacagg aacttttttc caagtttgaa
    14101 acgcagcatc ggcagcttta actgcttcgg ctgtctctgc tttgctagac aacggtacat
    14161 tcgccagcgc ttcttctgta gccggattca ttacttcttc aaactctgtt gagcgactag
    14221 cgacccaacg accatcaata taatttctta aaaatcttgt cattta
//
LOCUS       DACBYO010000076        14204 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.076, whole genome shotgun sequence.
ACCESSION   DACBYO010000076 DACBYO010000000
VERSION     DACBYO010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.076"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            239..2710
                     /locus_tag="IVD26_002179"
     CDS             239..2710
                     /locus_tag="IVD26_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP6080114.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2813..4549)
                     /locus_tag="IVD26_002180"
     CDS             complement(2813..4549)
                     /locus_tag="IVD26_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAP6080115.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4546..5250)
                     /locus_tag="IVD26_002181"
     CDS             complement(4546..5250)
                     /locus_tag="IVD26_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6080116.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5381..5884
                     /locus_tag="IVD26_002182"
     CDS             5381..5884
                     /locus_tag="IVD26_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAP6080117.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            5844..6182
                     /locus_tag="IVD26_002183"
     CDS             5844..6182
                     /locus_tag="IVD26_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAP6080118.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6203..7621
                     /gene="ffh"
                     /locus_tag="IVD26_002184"
     CDS             6203..7621
                     /gene="ffh"
                     /locus_tag="IVD26_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAP6080119.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7733..8311
                     /locus_tag="IVD26_002185"
     CDS             7733..8311
                     /locus_tag="IVD26_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAP6080120.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8315..8836
                     /locus_tag="IVD26_002186"
     CDS             8315..8836
                     /locus_tag="IVD26_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP6080121.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(8915..9469)
                     /locus_tag="IVD26_002187"
     CDS             complement(8915..9469)
                     /locus_tag="IVD26_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP6080122.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9722..9997
                     /gene="rpsP"
                     /locus_tag="IVD26_002188"
     CDS             9722..9997
                     /gene="rpsP"
                     /locus_tag="IVD26_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAP6080123.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10009..10260
                     /locus_tag="IVD26_002189"
     CDS             10009..10260
                     /locus_tag="IVD26_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAP6080124.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10385..11176
                     /locus_tag="IVD26_002190"
     CDS             10385..11176
                     /locus_tag="IVD26_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080125.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11346..11867
                     /gene="rimM"
                     /locus_tag="IVD26_002191"
     CDS             11346..11867
                     /gene="rimM"
                     /locus_tag="IVD26_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAP6080126.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            11857..12618
                     /gene="trmD"
                     /locus_tag="IVD26_002192"
     CDS             11857..12618
                     /gene="trmD"
                     /locus_tag="IVD26_002192"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAP6080127.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12754..13101
                     /gene="rplS"
                     /locus_tag="IVD26_002193"
     CDS             12754..13101
                     /gene="rplS"
                     /locus_tag="IVD26_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAP6080128.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13359..13652
                     /locus_tag="IVD26_002194"
     CDS             13359..13652
                     /locus_tag="IVD26_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAP6080129.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(13740..13853)
                     /locus_tag="IVD26_002195"
     CDS             complement(13740..13853)
                     /locus_tag="IVD26_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAAX protease"
                     /protein_id="HAP6080130.1"
                     /translation="MYAPGTILLTIAYLTANRSLAFIIAIHILNNVLGFVL"
BASE COUNT         4752 a         2559 c         2904 g         3989 t
ORIGIN      
        1 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
       61 gaaaatcgcc ttcgattttc caccaacaca aaatattata gaaccctttt tttttgctat
      121 atgacaggaa tgaaaggtgt ttgcaagctt aatgtgagga acactttcca tatctgttct
      181 atactggata ggagaagttt ggaaatatcc agaaaacgaa atcaatcgag gtagccacat
      241 gaagaataaa tggataaatc gaagtaaaaa aaagaaagta acacaaagat catcagataa
      301 agtcatccgt ctttttccat cgtataaaga aggattaacg gcagatcaag tcaaggaacg
      361 aatagaaaaa ggtgcagcaa ataattcagt cgatcccaca ttcaaaacaa atcagcaaat
      421 cgtattggaa aacatattta cgtatttcaa tttgatcttt cttatcttag ccattttgct
      481 ttgtttagta gaatcctata agaacttgac ttttttacca gttatcatag ccaatacagg
      541 aatcgccatt tttcaggaaa ttcgatccaa aaagatcttg gacgaactaa atgttttaaa
      601 tacagcaaaa gtcaatgtca tacgagacgg gatagaacaa acaatagata tagaagacct
      661 tgtaatagat gacattgtta ttttagagac tggatatcaa attccagcag atgcagaggt
      721 cgtggaaggg aaactgcaag ttaatgaggc tttattgaca ggcgaagcag atgaaataac
      781 caaagaaata ggtgatccat taatgtccgg cagtttcatt gtttccggaa aagcttacgc
      841 ccgattagac aaagttggag cagattcgta tatttcccag ctgacagtca aagccaagac
      901 aatgggagaa ggagaacagt cggagatgat tgcttctctt aatcaattga tcaaatggat
      961 tgggatcatc attattccta tcggtatcct gcttttttct caaagttact tttttaatgg
     1021 aaacacgatc aaagaaagtg tcgttgcaat ggaagcagca ttgatcggta tgatacctga
     1081 aggactgtac ttgctgacga cgattgcatt agcattaagt gcgactaaac tagcaaagca
     1141 aagagttctt ttacacaata tgaaaagcat tgagacattg gcaagggtaa atgtcctttg
     1201 tgtagataaa acaggaacga tcacagaaaa taaaatgtct gttcaaaaaa tgatcgtctc
     1261 taaaaaacaa gaaataatca gtcagtcaga tcaattggaa gcatgcattg ctgactatgc
     1321 aaaagcgatg gcaggagaca atgcaacaat ggaagctgtt aaagcatatt ttacaaaaac
     1381 cactgatcaa tcctatcacc atgttattcc tttttcttct gtccaaaaat tcagcagtgt
     1441 agcgttggca gacaaggtgt atgttttagg agcgcccgaa atggttttgc gcgatcaatt
     1501 gccggaatat gcggaagagt ttgtttcttt cgctgaaaaa ggctatcgcg tgttggtctt
     1561 tggtgtgtac gatgggattc ttgaagaacc agtattgaca gaagcagtca caccattagg
     1621 ctatattctg attgctaatc ctatcagaaa agaagcaaga gccacatttg attacttcaa
     1681 aaaacagcaa gtagccatca aagtgatttc tggagataat ccgctcaccg tatccaatgt
     1741 agctgtccaa gcagggattt cacatgctga tcagtacgtt gatgcatcta aattatcaga
     1801 agaagaatat gaagcagctg tcgaaaaata tacagttttt ggacgcgtca agccagaaca
     1861 aaagaaaatc ttcgttcaat tgataaagcg taacaataca gtagctatga caggtgatgg
     1921 cgtgaatgat attctagcca tgaaagaagc agactgcagt atagcgatgg cttccggaaa
     1981 tgaagccgcc atgcaggcct cacaagtggt cttacttgat tctgactttt cacgcatgcc
     2041 agaagttgtt gcagaaggac ggcgcgttgt gaacaatatt gagcgatcag ccagcttgtt
     2101 tttagtgaag aatattttct cctttttgct ctcactgttt tcagtgatct ttgctctgac
     2161 ctatccttta gaaccatcac aaatcacatt gattagtttg tttactatcg gacttccatc
     2221 tttcttgctt gctctagaag aaaacaaaaa gcgaatcaga gggaaattca tcatgaatgt
     2281 gatggaaaaa gctgtgccag gtggactaac agatatgatc gtagtcggtg cgttggtgat
     2341 ctgcggggtg actttgaatc taaataaaac agatgtttct acagcatcta ccatgctttt
     2401 gattgcagta gggttcctcg ttctctataa aatctgttca ccgctgaata aattcagaag
     2461 tcagatcatt cttttctgtg ctagcggtaa ctttttttcg gtcatctttt tgcataagct
     2521 gttttcaatc accggtatct cagctgtatc acttttgctg ttgagcattc tatttttctc
     2581 ggcagattcg atttttaggc atttgaccac attggtagaa tatttgtttg aacgtaaaaa
     2641 tgaaaaagag caaaagccgt ttagtcgcgt agctaaaaaa tttctatcga tatttaaacg
     2701 agaaaattga cgaaaagtat ctcaaaaaag agtaaaaaag aacaaccact cgtgtatctt
     2761 tcgaagcagg atgagtcatc caactttaaa acgcacgagc agttgctctt ttttacattt
     2821 tcggaatggt aacggtgaaa gtcgaacctg ttccaagatg actgtctaca gtaatcgtac
     2881 cattaaggag ttgcacgtag tcttttacaa tcgctaaccc taatccggtc ccgcctgaat
     2941 gtcggcttcg cgccttgtct acgcggtaaa aacgctcaaa gatccgttcc tgatcctcaa
     3001 tgtcgatacc tataccaaag tcttggacag aaaacgatag atcatctgtt gcctgatagc
     3061 ggataataat ctcgctgtcg ctttttgaat attggacagc attttcaatc agatttttga
     3121 taattggata aaggatatct gttttagtag taaatggttc gttctttcca atcaatcgaa
     3181 tcgtcaaccg tttcttttcg atgattggct gataattttg aacgatttgc tggaaataag
     3241 gttctgtata aattgtctgg atctcgtaag aattctcgcc atcttttgac agctggatga
     3301 tttcccgaat cagtttatct aaccggatcg catctttttg catgatctca agaaaagaag
     3361 tcagagtttg cgggtcatct tttgcaccat ccagtaaagt ctcggtaaaa ccaatcagtg
     3421 aagtcacagg agtttttaat tcgtgagaga cgttgccaac gaaatccttt tgtagctttt
     3481 ctaaacgtcg cactttcgtt aagtcatacg ccacccctag aatctgtccg gtaccttctg
     3541 aattagtaaa gtagcgcaaa ctcaagtcta atgtctgccg accttctgta agggtgatct
     3601 cctgatggat cagcggatgc tcaggagtca cttgatgaat cagctgaatg agttttggct
     3661 cttgaatgac ttctgtgtac cgctgttcag gttgatagct taccacgttt aaatgtagct
     3721 gcatctttgg attaagcagt agtaaacgag aatcagcatc atcaatcagg aatacgccaa
     3781 tcatcagttc gttcagtaac gtatataatt gctcttctgt ggtagtacac gcccgataca
     3841 tcttactcat ttgttcgctc aacgcattaa tcgtctgata caattcttcc cattgatcgg
     3901 gtgtttgcat gattacttcc gcctgattag gattttgcac catttttttt agtacgggca
     3961 gcacggtttt caatggctgg tttttttgat agatcagata atagatcatt cctgcaagaa
     4021 caaggaagaa agacagaaag aagaaaaaga cccaacggcg aaaactctca gttctcggta
     4081 aaaaaacgct tgtcggttct gcgatacgta aaatggcttc taactggcca ctttttttga
     4141 ctggtaatgc gacatataaa agatcctcat tcaaagtagt acttttgcgc aaagcgctac
     4201 ctaggttccc accattcaat acggctttga tttcgggacg ggagtttcgc tgttcattca
     4261 atgtttcatt gtttgtgtca aataagatct ttccagtagc atccattaaa gtaatccgtt
     4321 cgttcgactg atggacgaat tcttccaaag cagttttgtt ttgcgctgct tggaggtttt
     4381 cgacatctaa ttgccggatc agcagttgtg ctttttttgt caggtagctt tcttgctgtt
     4441 ccacgatctg ctgttgaaaa taatgggaaa tcaattgcca gccaccaaaa aacaaactaa
     4501 ctaaaagaat aagaaagaag agacgttcat aaattttttt ccatttcatc gtttgggttc
     4561 ctgaaactta tagccaaatc ctctaatagt caccaagtac tttgggtgtt ttggatctcg
     4621 ctcgattttt tctcgcaaat gactaacgtg tacatctacg attcggcttt gtcctgcgaa
     4681 gtcaaaattc caaatgcggt ctagcaatgt gtctcggtcg atcacacggt cttttcgttt
     4741 catgaaataa acaagtaatt caaattcttt cggtgttagt tcaatcagat ggtcgtctac
     4801 ggtcacttga taattggtca aatcagcagt gatttgtcca atcgatagat attcaggctc
     4861 agcttcatct tttgattgct tacgaggttc aattcgtctg aatattgctt tcatacgggc
     4921 taatacttcg cgaggactaa atggtttggt caaatagtcg tcagcaccta tttctaggcc
     4981 aatgatccga tccacttggt catctttagc cgtcagcatc aaaatcggtg tttcattttt
     5041 ttcttgacgc agccgctgag tgatctccat gccatccatc gttggaagca tcacatctaa
     5101 aatgatgaaa tcaaatgatt gttctaatgc taattctaat ccttcgcctc catctgtggc
     5161 actggttacc ttgtagcctt ctttttccaa attgaacgtc aagagcgtta caatagaagg
     5221 ttcatcatca acaactagta tttttttcat tcaaatctcc tttaaatagg tttcattctg
     5281 tttatatttt agcatagaat cagtacaaag ggctatttta caaaagaaat aaatggtata
     5341 ataggaaggc actttgctga atagaaagga agagcagtca atgattggaa tcagtgcatg
     5401 tttaggcggt ctggcctgtc gctatgatgg acagaaaaaa gaagtaccag aattgatgga
     5461 actagttgaa actggagaag ctgtcatggt ctgtccagaa gtgatcggcg gattaccaat
     5521 tcctagagat cccgctgaaa tcattggtgg aaatggattc gatgtgtgga aagatcaagc
     5581 aaaagtatgg acgacaagcg gcgaagatgt aacggaagcg tacaaaaatg gcgcgatcaa
     5641 agcctatcaa aaattgcagg aaaaacacat tgatctagtc atcatgaagg aaaaaagccc
     5701 ttcatgcgga acccattcga tttatgacgg aagtttttcc ggaataaaaa aaaatggtgc
     5761 cggagtggct actgcttatt ttattcagca aaaaatgact gtgctctctg atgaagaatg
     5821 gctgaaaact agaggtgagc agaatggaaa tcgaaaagac caatcgaatg aacgcgctct
     5881 ttgaatttta ttcgacctta ttgacagaaa aacaaatgaa ctacatggaa ttatattatg
     5941 cagatgattt ttcattaggt gagatcgcgg aagaatacga agtaagccga caagcagtat
     6001 atgacaatat caagcggaca agcaagatct tggaggatta tgaaaaaaaa ctccatcttt
     6061 tttctaatta tattgttcga gaacaggtat tggaaaatat gactgcatat attacagata
     6121 agtacccgga agataaaaaa ctacttgaat atgtacagca aattcaagca atcgaagaat
     6181 aaataaaagg aatgaagaaa atatggcatt tgaaagctta actgaacgtc tccagcaggc
     6241 gatgggaaaa ataagaaaaa aaggaaaagt atcagaagct gacgtaaaag aaatgatgcg
     6301 ggaaatccgc cttgccttac tagaagccga tgttaacttg caagtagtca aagattttac
     6361 taagcgcgta cgcgaacgtg cggtaggggc agaagtgctg gaaagtttat cacctgcaca
     6421 acaaatcgta aaaatcgttg atgaagaatt gacgatcaca cttggttctg aaacagcaga
     6481 gttaaataaa tcaccaaaaa taccaactgt tatcatgatg gctggtcttc aaggggcagg
     6541 taaaacgacc tttactggta aattagccaa ttatttaaag aaaaatgaaa atgctcgtcc
     6601 gctcctaatc gcaggggacg tatatcgacc agctgcgatc gaccaattga aagtattagg
     6661 tcaacagcta gacgttcctg tatttgatat gggaactgaa gtcagcccgg tagagatcgt
     6721 ccgtcaaggg atggagttag caaaagaaaa gaaaaacgac tatgtattga tcgatacggc
     6781 aggacgtctg catatcgatg aaacattgat ggatgagttg aaacaaatca aagaattgac
     6841 gcaaccaaat gagattttgc ttgttgtcga tgccatgact ggtcaagatg ccgtcaacgt
     6901 agctgatagc ttcaaccagc aattaggtat tacaggggtc gtcatcacta aacttgatgg
     6961 ggatactcga ggcggggcag cactatcgat ccgctcagtg acaggcgcac caatcaaatt
     7021 catcggttct ggtgaaaaat tgactgactt agaagtattc cacccagatc gtatggctag
     7081 ccgtatcctt ggtatggggg atatgctgac attgattgaa aaagcgcagc aagactacga
     7141 cgagaaaaaa gcggaagaac ttgcacagaa aatgcgggaa aattcattcg atttcaatga
     7201 ctttattgaa cagcttgatc aagtgatggg tatgggccca ctggaagatc taatcaaaat
     7261 gatcccagga atgaatcaag tccctggaat cgaaaacgtc aaggtagatc caaaagatgt
     7321 tgaacgcaaa aaagcgatgg tttattctat gacgccagca gaaagagcaa atcctgatct
     7381 gttgaaccca agccgtcgtc gccgaattgc tgccggttct ggaaacagtg ttgttgaagt
     7441 gaatcgaatg atcaaacaat tcaaggaatc aagaaaaatg atgcagcaaa tgtccaaagg
     7501 ggatatgaac atcccaggta tggaccaaat gtttggttca ggcgtcaaag gaaaactagg
     7561 caaaatggcg atgaatcgaa tgatcaagaa aaataagaag aaaaagaaaa aacggaaata
     7621 agatgaaaaa aacagcttcg gtacagactg aaaatgtcta ctgccggagc ttttctatca
     7681 gcaattttta ttctttacta atacaattac tctaaacgaa gaggtggcac agatgagatg
     7741 tccgtggagt gaacaaacag aaagtatgcg gcaatatcat gatactgtct ggggtgttcc
     7801 tgaatatgat gaccaaaagc tgttccgaaa attgatgctt gatattaatc aagccggatt
     7861 gagctggcag acgattttaa ataaaagtga agcattcgat gaagcatatg atcgattcga
     7921 tatcaaaaaa gtcgcaaatt atggagaaac aaaaatcagt gaactaatgg aaaacaaagg
     7981 aattattcgt aaccgaagaa aaatcgaagc agccgtccaa aacgccaaag cagtcttgaa
     8041 aattcaagaa gaaatcggca gtttttcaga gtatctttgg tcgttttcta atggaaaaat
     8101 cgttgattct tcttatcatt cacaagaaga agtcccaaca acaagtcctc tttcagatga
     8161 attagcaaaa gatctaaaga aaagaggatt taaatttatc ggaagcacaa caatctatgc
     8221 ttttttagaa gctgtcggga tcatcaatga tcaccttgac agttgtttcc gcaaagaaga
     8281 ggtcgtacgt atcggcagaa agggcgaata aagcatgcga aaaatcatat tttatggtgc
     8341 tataagttta gatggctatt tggcaacgaa aacggatgat cttcaatggc tttttgacac
     8401 tccaacaggt aagcaaacta cttatgaagc tttttatgaa acaatcgata cgaccatcat
     8461 gggcagaaaa acttatcagg aagcaaaaaa atatttggag accgaagcaa tttatccaga
     8521 gaaaaagaat ttcgtttttt ccacccacgc acaattacaa ttgccagatg ctgaggtcgt
     8581 aaacgaagat cctgttgctt ttctaaaaaa tctacaaatg acagaaggaa aagatatctg
     8641 ggttgtgggt ggcggtcgat tgatcaaacc gctattggaa catcaaatga ttgatgaatg
     8701 gtatatccag attacccctg tattattagg ggacgggatt cctttattcc aaaaaggaac
     8761 atatgaagcg cgttttgaaa tgctagacac gacacgattc ggtgaattta tcgaattgca
     8821 ttatgtacga aagtagaagt aaataaaata aaaaaggcaa ctatatgcag aaatgtcctg
     8881 tacatagttg ccttttttat taccgttatg ctttttactc tgttaatttg ttagaaaaat
     8941 ctagatacgc atctaaaatc gtttggaaga aacttaatgt tccttcaacg atattaccat
     9001 tttcatcaat tagattcgca acgtttccga tatatgcttc cggttgctgc aaggttggca
     9061 cattcaaaaa gacaagtgat tggcgtagat ggtggtttgc gccaaagccg ccgatcccac
     9121 ctggtgatgc agtaacgact aaacctggtt tatgatccca aacactgtgt ccataaggtc
     9181 ttgagcctac atctaaagca tttttcaata ctgctggcac agaacggttg tattcaggag
     9241 taacgaaaac gacaccgtct agtcccctca cttcctcacg aaaacgagtc cattcagcag
     9301 gagcctgttc tggagtttcg agatcctcat tgtaaaatgg cagatcatcg atttttacaa
     9361 atacactttc gtacccttca ggaagcaatt tcgcaaaagc ttctgctact tttttgttgt
     9421 aagaatcttt tcttaaacta ccaataaaaa atccaatttt ttttgtcata cgatttttcc
     9481 tccttcaaac tatctataat aatcttacaa aagataagta actggagcaa ataaaaacac
     9541 ttactgacaa aagctacata gaagatagat tacttatttt taacaaaaaa gaagtctaaa
     9601 atcttctatt ttctaaaaaa aatcgaattt aatcaagctg taaagaaaaa aagctttaca
     9661 gggtaaaaaa aaactgttac actacatctt gtgaataaaa caatggaggt ggaaataaat
     9721 aatggcagtt aaaatccgtt taaaacgtat gggttctaaa aagagtccgt tttaccgtat
     9781 cgtcgtagct gattcacgtt ctcctcgtga tggacgtttc atcgaaactg taggtactta
     9841 caatcctttg aaagaccctg cagaagtagt tttaaaagaa gacttagttc ttgactggtt
     9901 atcaaaaggt gcacaacctt ctgacactgt acgtaacatc ctttcaaaag aaggcgttat
     9961 gcaaaaacac cacgaagcta aattctcaaa gaaataaggt gaccggatat gaaagattta
    10021 agcgacttag tcttaacaat cgttcgtccg ctagtcactt atcctgatca agtcaagtta
    10081 gacgtcgtag agtcgaaaga cttttacgag tacaatctaa cagtggctcc tgaagatatt
    10141 ggccgtatca ttggaaaaca agggcgtgtt gctaaagcaa tccgcacaat cgtttacggt
    10201 gttcggatca atgcaccgaa aaaagtgcgt ttgaatatca tcgatgataa ggaaaagtaa
    10261 ataaacggtc tgtactcgaa ttttcgagtg cagctttttt gtttttttta ttaattgaag
    10321 aaatgattat ttggcaaaac aagcaagaaa gcgtatcctt ataggaggag ggagtgaaca
    10381 gccaatgaga aagaaaatgt tatttattcc atttgctcta ttgttaagcg cttgtagttc
    10441 ggttactcaa gaatcagaca atacacatct atcaagcagt atatctgaaa ctgttaccag
    10501 tccagaaaaa agtagtacca aaacggcttc caccactgaa caaacaatgg ctacctcaaa
    10561 taatgagaaa aagactgctt tagaccagtt gaaagaacaa cagccaaatg ttcccatgcc
    10621 tctagatgta ccagtctctt caggctatct caatatcgca gcgacacata caaagcaagg
    10681 ttattctatt ttatattaca gaacagatcg tcccctcggg ttgaatgctg acgaattgaa
    10741 tcaagaaacg cctattgcaa cctatctata tcaatatggg tttgcttcta gtcaagaaac
    10801 aatccaagtt ttgcagccat ttgagatcga cacaaatggt cagcaagtgg acttaggttc
    10861 tcgaatcaca gggtatcagc aaggtgcagc aggttcaagt tttcttgaat ggcaagaagg
    10921 aaactggcgt attcgaatcc gtgggaataa tatagaaggc caagatccct tactattagc
    10981 taaagaaatc gtagcttatt tggaagaaaa cagtctacca gcacctgaac aatttggtaa
    11041 aattactgtt gatatgggtg atacgacgaa tcgagccgta gaagtaagct ggcaagaacc
    11101 gaaaaatgcc tatacgatca ctcatcaaga tcctatgtct gcgttgaaga tggcagtttc
    11161 tatgaagagg ttgtgaaatc agcgcgctga tctgagccca tcatttaact ccaagtcaca
    11221 ggaagtaatc aaaaatagca cgccgcattt ttgcataatt ttggcttaat accttaaaag
    11281 aaaactagaa ttgcctcttc acacatgcta aaataaaaca gacaaaaaag aaatggggat
    11341 ataagttgac tgaatacttg aatgtaggaa aaatcgtaaa cacacaaggt atcaaaggcg
    11401 aagtccgtgt tatctcaaca acggatttcc cagaagaacg ttacaaaaaa ggaacggtgc
    11461 taacactatt ccaagacgga aaagcacctg tggaattaac agtcaaaagt catcgcaaac
    11521 ataaaaattt tgacttattg agttttgaag gacatccttc tatcaatgat gtggaaaaat
    11581 atcgggatgg catattaaaa gtgtcaaaag acaactctgt agatctagct gaaaatgaat
    11641 tctattacca tgagatcatc ggtctgcatg tattagaaga tggaactgag ttaggtaaag
    11701 taaaagaaat cttgtcacca ggtgccaatg atgtttgggt cgttcaacgt ccgaaaaaag
    11761 ctgatatatt gcttccatat atcgcttctg tcgtcaaaga agtcgattta gaagctggag
    11821 tggtccgtgt agaaattcca gaaggactga ttgacgatga agattgatgt attgacttta
    11881 tttccaagaa tgtttgaagg tcctatgggg gaatccatca tcggtaaggc tgtagataaa
    11941 ggattattag atatcaatat ctctaacttc cgcgattatt cagataacaa acatcagaca
    12001 gtagatgatt atccatacgg cggtggagca ggtatgctgc tcaaagtcca gcccatctat
    12061 gataacatcc aagccattga aaaagctgca ccggatgtca aaaaaagagt aattcttctt
    12121 gacccagctg gtaaacgatt cgatcagaaa atggcagaag aattttcaca agaagaacac
    12181 ttagtattca tttgtggtca ttatgaggga tatgatgaac gtatccgcac attagtgaca
    12241 gatgaagttt ccttaggaga ttatgtcctt actgggggag aattaggtgc gatggtcatg
    12301 atcgatgcaa cagttcggct tttgccagat gtgttaggga atcagacttc agctcaaacg
    12361 gattcttatt caaccggttt attggaacat ccccaatata ctcgcccggc agaatataaa
    12421 gggatgaaag taccagaagt attgacaaat ggaaatcata aattgattga agaatggcaa
    12481 ttaaaagaat cactaagaag gacctatcaa cgtcggcctg atcttttgga aacacttgaa
    12541 tggacacctc aaatgacgaa atttttagaa gaaatcaaga aagaagaaca agaaaaaaca
    12601 gcagatgaag ccaagtgact ttttctaaaa tcttctttac agtaggttga taatatgtta
    12661 gtattttatg gtgagtgcaa aagcacttaa ctattacgat attccgctgt gagaaaagct
    12721 cataagaata tttggaataa ggagaagaaa accatgaatc cattaatcga agaattaaca
    12781 aaagaacaat tacgttctga catcccagcg ttccgccctg gtgacactgt gcgtgttcac
    12841 gcaaaagttg ttgaaggtac tcgtgaacgt atccagttat ttgaaggtgt tgttatcaaa
    12901 cgccgcggtg ctggaatcag cgaaacttat acagtacgta aagtttctaa cggagtgggc
    12961 gttgaacgta cattcccatt gcatacacca cgtgttgcaa aaatcgaagt agttcgctac
    13021 ggtaaagtac gtcgtgcaaa attgtactac ctacgtgcat tacacggaaa agctgctcgt
    13081 atcaaagaaa tccgtcgtta atcattgtta tcagactgag aaagaaccct tggtattcaa
    13141 gggttctttt ttcttagcat gtaatttgaa caccctgatc cagttttttc tttaattatt
    13201 ggtaggggag aataatggat tagaataaat ctacctataa gtagtagtaa aaaaaagagc
    13261 actatgataa tatctttctt aagagtaacc gctttaataa aaaatccaga atattctaac
    13321 ataaatggag tattcttaga atcaaaagga gaaagaagat ggtttatact tatacggagc
    13381 aagaaaagat gaaagtttta gacacattca tgaatgatgg aaaagtaaaa caagtaccaa
    13441 gttcaacaaa aaagaaatac atcctattga aagaagtctt gaaacgcttt gaccatggag
    13501 tgacttatac agaaacagag gttaattcga tactgctgaa cgtattttct agtggcgatt
    13561 atgtcgaaca aagacgttat ctaatcacat ttggcttttt caaaagaagt tcagacggtc
    13621 gggcatatca gatgatggga attgaaaatt agaagtttta atttatactc attgaaaaaa
    13681 gttcaagtat gcgatattgg ttctacaccg catacttgaa ctttttttgt catctgtatc
    13741 tataatacaa agccaagaac gttattcaaa atatggatag ctatgataaa agctaatgag
    13801 cgattcgcag ttaaataagc aatcgtcagt aaaatcgttc caggagcgta catgaaaaaa
    13861 tcaattggat gcgttacatg aataaagata attctctttt atttgtacga ataaatacca
    13921 aaacgtacct cctaaaatta gattttggac agatgccctt taaaaagata acaagatttc
    13981 gttcttgaaa caatatatat gcttttattc caatgaggtt gtgaaaacag tattttgtcc
    14041 tgagcgttag aaaattgaaa atggggaata gcaactcgta ctttaccatt ttttaagtga
    14101 atacaagatc agctaattga acaccgttta ttcgtgatga gggacacaac actgcagtcg
    14161 acacatttct cttttatgtt caaagataac aaatatttaa aaca
//
LOCUS       DACBYO010000077        13959 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.077, whole genome shotgun sequence.
ACCESSION   DACBYO010000077 DACBYO010000000
VERSION     DACBYO010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.077"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..135
                     /locus_tag="IVD26_002196"
     CDS             <1..135
                     /locus_tag="IVD26_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6080131.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
     gene            complement(313..2310)
                     /gene="tkt"
                     /locus_tag="IVD26_002197"
     CDS             complement(313..2310)
                     /gene="tkt"
                     /locus_tag="IVD26_002197"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAP6080132.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2412..2663)
                     /locus_tag="IVD26_002198"
     CDS             complement(2412..2663)
                     /locus_tag="IVD26_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAP6080133.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2810..3433
                     /gene="lexA"
                     /locus_tag="IVD26_002199"
     CDS             2810..3433
                     /gene="lexA"
                     /locus_tag="IVD26_002199"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAP6080134.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3613..3831
                     /locus_tag="IVD26_002200"
     CDS             3613..3831
                     /locus_tag="IVD26_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080135.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4120..4632)
                     /locus_tag="IVD26_002201"
     CDS             complement(4120..4632)
                     /locus_tag="IVD26_002201"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAP6080136.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="IVD26_002202"
     CDS             complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="IVD26_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAP6080137.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7085..7519)
                     /locus_tag="IVD26_002203"
     CDS             complement(7085..7519)
                     /locus_tag="IVD26_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAP6080138.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7529..8317)
                     /locus_tag="IVD26_002204"
     CDS             complement(7529..8317)
                     /locus_tag="IVD26_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6080139.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8314..9255)
                     /locus_tag="IVD26_002205"
     CDS             complement(8314..9255)
                     /locus_tag="IVD26_002205"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAP6080140.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9432..10019)
                     /locus_tag="IVD26_002206"
     CDS             complement(9432..10019)
                     /locus_tag="IVD26_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAP6080141.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10240..11553)
                     /gene="obgE"
                     /locus_tag="IVD26_002207"
     CDS             complement(10240..11553)
                     /gene="obgE"
                     /locus_tag="IVD26_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAP6080142.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11841..12851
                     /gene="gap"
                     /locus_tag="IVD26_002208"
     CDS             11841..12851
                     /gene="gap"
                     /locus_tag="IVD26_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP6080143.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12936..13871)
                     /locus_tag="IVD26_002209"
     CDS             complement(12936..13871)
                     /locus_tag="IVD26_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP6080144.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3863 a         3126 c         2454 g         4516 t
ORIGIN      
        1 ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct
       61 agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag
      121 ttttgtctcg cttaatttga caaataatat tctcaagaaa cacaaactaa tccgaagaat
      181 tctttgtttt gtcatttaaa tgtaacatag ccgaaaacga aaagtaatat tgatttattc
      241 ttctaacaca taaagaacag ctgtctccaa cttgcagaca gctgttctta tcagtcaaac
      301 aattgcttgg atctatgata gttgattgta cgtattcacg acattttcta ctgtaaatcc
      361 aaattcttct aaaattttag tgccaggggc agatgcaccg aaatgatcga ttgtaatcgt
      421 tgcgccctct gttcctacgt agcgttccca tccaaatgat gcagcagctt cgatagccac
      481 acgtttcttc actgatttag gaagtacact ttctttatat tcagaagatt gtttttcaaa
      541 gaggtcaaag cttggcatag aaacaacaga aacatctttg cctttttcag ccaattcttt
      601 ttgagctttc acagccaaat caacttcaga acctgttgca atcaaaatac cttctggtgt
      661 ttctccttgt gatggagaaa gaacatacgc gccttttttc accatttcat ctgctacttc
      721 ttttgtagaa ggcaatactg gaaggttttg acgactcaat acaaggatag taggcgcatc
      781 tgttgtctcc atcgctactt tccaagcagc acgtgtttca tttccgtctg ccggacgaat
      841 cacttgaaca ccaggcatgc agcgaacaga tgctagttgt tcaatcggtt cgtgcgttgg
      901 tccgtcttct ccgacagcaa ccgagtcatg tgttaagacg taaacaacag gagtatgttg
      961 gattgctgct aaacgaactg ctggtcttag ataatcgaca aagacaaaga atgttccacc
     1021 gtagatacga gttccgccat gaagttggat accattcata gccgaagcca ttgcaaattc
     1081 gcggacaccg aaccagatgt tgcgtccttc ataatgttca ggagtgaaat ctttatctgc
     1141 agccaccatt gtattattgg aacctgacaa gtccgctgaa ccaccccaga agcttggtat
     1201 agctttcgat aattcttgga tgacttcttt acttgaaaca cggcttgctt gactgcttcc
     1261 aacttcataa gttggcaatt ctgcatccca gttttctggt agtttgccat caaaagcatc
     1321 ttcaaattgt tgtgctaatt caggataagc ttttttataa ttggcaaaca tttcattcca
     1381 tgcatcttca gctttttgtc cttcttctat catcgtttga tggaagcggg cagctacttc
     1441 ttctggaaca gtgaaatctg gatactccca accataaact tctttagcca tcttgatgcc
     1501 atcttcacca agaggagcac catgaacagc agatgttcct tctttaggag caccatagcc
     1561 gatgactgtt tttacttcga tcaatgttgg tttgtctgtt tcagcttttg cttcttcaat
     1621 cgctttagag attgcttcta ggtcatttcc gtctttcact aagatatgtt gccagccata
     1681 tgcttcatag cgagcaccaa cgttttctgt gaaagctttt gaagttggac cgtctagtga
     1741 aatatcgttt gaatcgtata aaacgatcaa tttccctagt ttcatatgac ctgccatcga
     1801 acttgcttct tgagataccc cttccatcaa gtctccgtca ccgcatattg catacgtata
     1861 gtgatccatc acattaaagt tttctttgtt atacgttgct gcaaggtgcg cttctgccat
     1921 tgccataccg acagccattg caatcccttg tcctaatggc cctgtagtgg cttctacacc
     1981 atctgtatga tgtacttcag gatgtcctgg tgttttagaa tcccattgac ggaattgttt
     2041 caaatcatcg attgtcactt gatagccagc taaatgaagc aagctataca acattgctga
     2101 cccatgtcct gccgaaagaa cgaaacggtc gcggtcagcc cagttttttg atgtcgttgg
     2161 atttactttc aggtgttttg tccataacgc atatgccata ggtgctgcgc ccatcggcaa
     2221 tccaggatgt cctgagtttg ctttttggac tgcttcaata cttaatgtac gaattgtgtt
     2281 aacgccaagt tggtcaattt tgtcaaacaa aataacccct cctattaatt taggtttttt
     2341 ttacctttat ttcttacact ttcattctat aagatgtcac acgaaaaagc aatctttttc
     2401 agtatttttt actaaaagtt gtcatttcgg ttgtgtaagc cttttttctt ttggatttct
     2461 tttaattttt ccggggtcac gtcattgccc tcaggatcga cgactttcat tccttcgata
     2521 tgatgacgca taccggaacg aaaagcttcc aaatactctt tgcgcaagtt gatttgttct
     2581 tgttcttcgg cttttgagag accattttcc ttctttttac gtgcaagttc attgatccgc
     2641 tctatttttt caggtgacag catgctcagc cctcctttta ctctccttca tattatataa
     2701 aaactgaaaa aaaaacaact agataaacta aataaaatac gaacattcgt ttgatttagc
     2761 gctttttata tggtactatt tatttatcaa gtgaaagaag gtgtaccttg tggcccgaca
     2821 aactgaatca agacaaatcg aagtcttacg atatatccat gaacaagtaa cccaaaaagg
     2881 atacccgccg actgtccgtg aaatcgggga agctgttcag ctttcttcta cttctactgt
     2941 tcacggtcat cttgcacggc ttgaaaaaaa agggtttatc caaagagatc cgacgaaacc
     3001 tcgtgcaatc gagttgacaa aacaaggttt agaaaagatt gggattcgtc caacaactat
     3061 tccagtactt ggcgtcgtaa cagctggaga acccatttta gcagtagagg atgcttcaga
     3121 cttctttcca atccctccta atctttcttc cgaagaaggc agtctcttta tgctgacaat
     3181 tcgtggagat agtatgatca atgctgggat attggatggt gacaacgtga tcgttcggaa
     3241 gcaagaaact gctcaaaatg gcgatattgt cattgcaatg actgccgagg acgaagcgac
     3301 ttgcaaacga ttctataaag aaaaaaactt tttccgtctg cagcctgaaa acgacttgct
     3361 cgaaccaatc atcttagatc aagtatctat attaggacga gtagtaggac tttatcgtag
     3421 tcatatctat taattgctac taattaaaag aaaacttttt aaaaagagtt tgagacgttg
     3481 gtctcaaact cttttttcgc ccgggttctt cttctttcaa atttttatca cttccctctt
     3541 tacaaaccga acaaatattc gtatactaaa tatacgaaca attgttcgca taaattaaag
     3601 aggtgagaat tcatgaaatc aatgagacgt cttggcttag tattaactgt tttgttttta
     3661 ggtattatta ttggtaattt cggcatacgt ccagctttac ttgtgtttgt tccgttattt
     3721 actttgtggt tcatgttgtg ggatgaaaag aagtaccgtc aatctgagcg gcgcagaatt
     3781 catgaagatc atttctatca tgagccctac tacagatcca ggcaatcata ataaggattg
     3841 actgctaatt attcaaaaga caagaagtta aacttttacg ggggtgtgac aaaaatcggt
     3901 cacatccttt ttttcgaata aacggtgttc taaagccagt ttttcggtat taagtcaaat
     3961 tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat ttataaaaaa
     4021 atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt taaaatcgct
     4081 tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca ttaatgtaat
     4141 gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga tcaaaaatgc
     4201 gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt tgattgttcc
     4261 tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa tggcatcctt
     4321 atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga tggtttctcg
     4381 aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat aagcaacagg
     4441 acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc gtttttcttt
     4501 tgcataattt acgatttgtt tagtagcttc ccgataagcg tcaccatctg ccatcagtgg
     4561 ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg caatataatc
     4621 ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg gtaggaatat
     4681 cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgtcgctgg tataatctgc
     4741 tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg ttctctattg
     4801 taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt tcagggatac
     4861 gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct tgagaatgga
     4921 tcaatttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa taggcctcat
     4981 caggtgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa acttctttca
     5041 gatccgctaa atcatctgga caatccataa caactagaga gtttggtttt cttttttcaa
     5101 ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg ataatctcag
     5161 gcacgaattt caacgtcgaa gaatcaaatg ctaaataaag gctaccttcc gacgttcggc
     5221 tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc acagaaaaat
     5281 cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa agctttccta
     5341 ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca aaagcgaccg
     5401 catcaagctg actcgatgca tcggaaagga caaatttcag atgctgttgg tttgctccga
     5461 ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa ggattatccg
     5521 taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact tcatttggca
     5581 gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga tgatcgacta
     5641 tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc gttaaaccga
     5701 ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca agcatttcaa
     5761 aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct tcttttaaag
     5821 taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca atgcccaaaa
     5881 cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta ttgaccatcg
     5941 ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg atctcattca
     6001 atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac gagacggcag
     6061 gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa aaaccgatcg
     6121 ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc tgaagtccta
     6181 tccgttctga atgatgaatg gcatcgattc ctaatgaaac aaggattcga ttctcatcag
     6241 tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat tctgcaggcg
     6301 gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc aaatctggaa
     6361 atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct ggtaaattct
     6421 caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga gcgtatgcta
     6481 ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt ccttcttcga
     6541 tcttttcttg gtataccgat tggtttggtc catacccatg ctcaaatcga tttggcagga
     6601 atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt gcactggtga
     6661 tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt acagcttctt
     6721 ggattcggct gattgcttta tccatatcgt gtatcagata cggatcatgt aattcttgtt
     6781 cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt tgccacagta
     6841 acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag gattcagaag
     6901 gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca ctcctaactt
     6961 agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa aaacagatca
     7021 gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt atgaaatatc
     7081 cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt tcttccggcg
     7141 ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa gcagcttcca
     7201 actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct tcaattttct
     7261 tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt tgcttttttt
     7321 gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc agcgcagaac
     7381 cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt acaggaacat
     7441 ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat ccaagaatca
     7501 cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg ctggctaaat
     7561 aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa ataaacggtt
     7621 gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc aacttggcag
     7681 gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca gccttatcga
     7741 agaaatttgt ctcgattgga cctggattca ctgtcgtaac agctacgcca agtggtttca
     7801 attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca gaataaaccg
     7861 ttgattttgc agttgccatt tttccagcca tagaggcgat attaatgata tgaccttgtc
     7921 ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct aagatgttga
     7981 cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg aaaatcccaa
     8041 aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc ttttcatata
     8101 attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc tctttgccgc
     8161 tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt gcgcaactta
     8221 taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga ccgcctgaac
     8281 tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct cgcgaaatgg
     8341 aatctcaatg ctatcaaaat ctttcataat cgtcgtgttt tcaaacactt cttgtgcttc
     8401 tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag taagtagcag
     8461 ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg aatggaaata
     8521 gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca gaatatcgct
     8581 attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa tagtcacgat
     8641 tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc catcttctag
     8701 ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa tacctaattc
     8761 ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac gataaccaaa
     8821 actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat cagtaaaaat
     8881 cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg tttgcgaaat
     8941 acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct ctaatggcgt
     9001 atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa tatgatcgcc
     9061 gtgtaaatgt gtaatgaaaa ttttaccgat ttttctcgga cgaatagtcg ttcgcaaaat
     9121 ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct cgtctaaaag
     9181 tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac ctgttcctaa
     9241 aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt ttagggtaaa
     9301 aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa cgttctaaag
     9361 cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt gagatcctct
     9421 gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt ttgcggatgt
     9481 ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc tttcgcatca
     9541 tgcacatctt tttcgacatc ttcataatcc aagcgagtaa tttctccgcc taattccatc
     9601 attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat cagtcctgta
     9661 gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc ttttatttct
     9721 ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa aatccctagc
     9781 ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga tttgttatta
     9841 ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg atcatggctg
     9901 acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt gatttctgaa
     9961 aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg tttgctcatt
    10021 aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgaa aaataagaaa
    10081 agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta tcacagctcc
    10141 tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct cccttaaatc
    10201 tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa attcaaattc
    10261 aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa gagcttcatc
    10321 cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat gatcgaaatt
    10381 cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg catctgaatc
    10441 acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag tttcttcttc
    10501 cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg ctgtagcatt
    10561 caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg ggatgtcatc
    10621 agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta gattttccgg
    10681 tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta gcaagcgtaa
    10741 gttataagta gataattctt tgttgatggc aagatagtct tcataaggat ctcgtccttc
    10801 catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat gacgaaggaa
    10861 ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca agtctgctgc
    10921 ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttaggtacga gcgtcgtgaa
    10981 atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag tcgatttccc
    11041 gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta gttcgatttt
    11101 tcgctcttgt cctggttcac cgttttcagc aatttccggt gcaggattcc gaggagaggc
    11161 aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg tttgaccatt
    11221 ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg ttccttgtgg
    11281 tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca tcccattttc
    11341 acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac gtaacccttc
    11401 atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg gtccgccgtc
    11461 aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc cagctttcac
    11521 atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt attcatttat
    11581 ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta tcggtgaaat
    11641 ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt ttatcatttg
    11701 gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa tattctttgc
    11761 gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac agcaccccta
    11821 ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt gggcgtattg
    11881 gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta gtagcaatca
    11941 acgacttaac aagtccaact atgttagcac aattattgca atttgactct actcatggta
    12001 cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc gaagcaactc
    12061 gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac ggtgtagata
    12121 tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg catttagatg
    12181 ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc atcgtctata
    12241 acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt tcatgtacaa
    12301 caaactgttt agcacctatg gcttatttct taaataatga atttgggatc gaagttggta
    12361 caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga cctgtaaaag
    12421 gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat tctactggtg
    12481 ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa ggacacgcac
    12541 aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg aaaacaaaag
    12601 taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat ccttcattcg
    12661 ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa ggttcgatct
    12721 ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt aaaactgttg
    12781 catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta gaaaaattcg
    12841 ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat ccagtcaaag
    12901 gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg gcttaaaaat
    12961 tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc atgctcggct
    13021 ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt atctaacatt
    13081 tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg ctggtttttc
    13141 ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac ttttgtcact
    13201 agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc tagctgataa
    13261 gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt cacattatct
    13321 ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac accgtataga
    13381 acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg tacatagtct
    13441 ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg tcctcttgca
    13501 tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt ggtcatcgtt
    13561 tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt cgtttcagca
    13621 ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca atcgcttcgg
    13681 ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg tgttgtacca
    13741 ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt ataaaaataa
    13801 ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag gattttcatc
    13861 caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg aattagtata
    13921 atcaaagaat ctctactatg caatgttcat ttttataac
//
LOCUS       DACBYO010000078        13945 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.078, whole genome shotgun sequence.
ACCESSION   DACBYO010000078 DACBYO010000000
VERSION     DACBYO010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.078"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            947..1420
                     /locus_tag="IVD26_002210"
     CDS             947..1420
                     /locus_tag="IVD26_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAP6080145.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1429..1656
                     /locus_tag="IVD26_002211"
     CDS             1429..1656
                     /locus_tag="IVD26_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6080146.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2292..2663
                     /locus_tag="IVD26_002212"
     CDS             2292..2663
                     /locus_tag="IVD26_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080147.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2919..3161)
                     /locus_tag="IVD26_002213"
     CDS             complement(2919..3161)
                     /locus_tag="IVD26_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP6080148.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3193..4095)
                     /locus_tag="IVD26_002214"
     CDS             complement(3193..4095)
                     /locus_tag="IVD26_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP6080149.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4108..4296)
                     /locus_tag="IVD26_002215"
     CDS             complement(4108..4296)
                     /locus_tag="IVD26_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAP6080150.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4310..4873)
                     /gene="amaP"
                     /locus_tag="IVD26_002216"
     CDS             complement(4310..4873)
                     /gene="amaP"
                     /locus_tag="IVD26_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAP6080151.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4911..5804)
                     /locus_tag="IVD26_002217"
     CDS             complement(4911..5804)
                     /locus_tag="IVD26_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6080152.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5882..6820)
                     /locus_tag="IVD26_002218"
     CDS             complement(5882..6820)
                     /locus_tag="IVD26_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP6080153.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6854..7204)
                     /locus_tag="IVD26_002219"
     CDS             complement(6854..7204)
                     /locus_tag="IVD26_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP6080154.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7237..8139)
                     /locus_tag="IVD26_002220"
     CDS             complement(7237..8139)
                     /locus_tag="IVD26_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAP6080155.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8132..8989)
                     /locus_tag="IVD26_002221"
     CDS             complement(8132..8989)
                     /locus_tag="IVD26_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAP6080156.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9323..10132
                     /locus_tag="IVD26_002222"
     CDS             9323..10132
                     /locus_tag="IVD26_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6080157.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10172..10669
                     /locus_tag="IVD26_002223"
     CDS             10172..10669
                     /locus_tag="IVD26_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP6080158.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11054..11127)
                     /locus_tag="IVD26_002224"
     tRNA            complement(11054..11127)
                     /locus_tag="IVD26_002224"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11091..11093),aa:Ile,seq:cat)
     gene            11314..11637
                     /locus_tag="IVD26_002225"
     CDS             11314..11637
                     /locus_tag="IVD26_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080159.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11801..12055
                     /locus_tag="IVD26_002226"
     CDS             11801..12055
                     /locus_tag="IVD26_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080160.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12125..12370
                     /locus_tag="IVD26_002227"
     CDS             12125..12370
                     /locus_tag="IVD26_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6080161.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12446..12811
                     /locus_tag="IVD26_002228"
     CDS             12446..12811
                     /locus_tag="IVD26_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080162.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12872..13435)
                     /locus_tag="IVD26_002229"
     CDS             complement(12872..13435)
                     /locus_tag="IVD26_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080163.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4090 a         2577 c         2304 g         4974 t
ORIGIN      
        1 ttcggagaat taaaaaatac aataaataac tttagttact ttaatgcgtt cttactttat
       61 ttttatatta tcatttttct tattcacttc tttggtttat actattctta taaataaaaa
      121 cgaggtatgt cctatgatga aaagattgta ctattcattg atcataacga ttggctattt
      181 gattgtatca aatctaggaa atatggtatt tggtatcagt aaagaattca gttggactac
      241 tacattatgg gaatctctat tctttttcat cttcgtattt ttgttacaaa attatcgaaa
      301 aaaataaaca tgtgccatct atctgttggc acatgtttta ggatttatgg tactttttat
      361 tcggcaatcc attttatttt tctacttctt cttaatacct ctaacacttt tgatttataa
      421 actaatccaa tgcatctact tgcgcttatt aagctatttc agctagatag taccacccca
      481 tgcgtcaatg cttgattttc cttttgtata acattgtata agcaataaag gacaaataag
      541 tggtgattac accaaaccat tgaataagaa aaattctgat acgtaaataa acatgaactt
      601 gaaaaaatta atgaatcggt tagctactac gtagttgtct tttttctcat acagttctgt
      661 taacttacac ttctcttcgc tagataataa aaaatcctcc aactgtattg tccaatataa
      721 tcccaggcat ctaaactagc attatagaag agacacacat agaatctaaa ataactggtt
      781 ttaaatgttt cttacaatca aaaaaagctg ttaaatgcac tccacacctt catactctat
      841 cattttttat aaacgatata tttttattgt ttttcgataa aaaatagttg ttttacaata
      901 attattctgc tatattttag ctatcaaaga taaaagaggg ataaaaatga aatttaaaac
      961 attgctatta aaatttgtcg ttttaggtat aagtgccgta tttattttgt tcggcgtact
     1021 tttttatact cagatcgcta caagcgaaaa aggattcaat tttgattggc agaccacatt
     1081 atttgtttct gtcatttact ttgcccttct cctagggatc gttattgctt atttcttatt
     1141 gaaactattg aaaaaaatcg aagataacca agctttttcc actcaaagct taaacatact
     1201 aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc ttttttggct tacttcctaa
     1261 atttatgaaa gtagcggatt tagacgatgc tccaggtttg atgttggtag gaatcgctgt
     1321 cgtattcatt ccttttgcag tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca
     1381 tgcgatttta cttaagacag atcatgattt gacagtgtga ggtgcgacat ggcaattatc
     1441 gttaatttag atgtagtatt agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa
     1501 gtgggcatta cgatggcaaa catctctatt ctaaaaaatg gaaaagcaaa agccatccgt
     1561 ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc
     1621 tataaaaatg actcgaatac tataccagaa gaataaaata aagtagaaca aacagtaaat
     1681 aaaaaataat ctgaatgata gatgtgtgag acttttagaa gttatttacg tctattattc
     1741 agatttttta tttcgattga ataccgtttt atctataaat aagatatgta ctgactcata
     1801 caaagggggc cttttcttct ccatgtacta tcacttttcc tgatacaact ggtttcctgt
     1861 tacgttgtag ttggatctgc ttttagtata atactttatt cattccacca gactgatagc
     1921 agtttgagca gtctaaataa tcatgtagta ttacaggcca ttctgtttca taccttgaag
     1981 tgcttaaaac ttcagctaat ggcccattgt gttaactctt actccattct tttttagtaa
     2041 gctcccatat atactgtaaa gccttctata tattatgtca tgttgctttt taacatttac
     2101 tatgtagttt tgataaaatg atttgaataa cagtgatgga caattctttt ttatttttaa
     2161 cattattttg ataataatga ttatttattt aaaaatacat tagataacat ttgttacgac
     2221 acgaaaaagc ttcacaaaca aatatcgtta ttttaaaatg agggcgaact cacacaatta
     2281 ggaggaatag tatgccattt attgtttact tttttctttc attactcgtg atctatattc
     2341 cattaccaac atttttcctg ctcgtcaatc gtctagcaga gcaacatgat acgattgctg
     2401 ctcttacgaa actttgttta cttctatttg tttgtctaga ttactttacg agctattatt
     2461 ggctaaaaca gacaagagta aaaaagagat attatttctt ccttgtcttt ttcaatctct
     2521 ttgagtttct gatccattgc tttttacttc atcagtatca tacgatccat ttgtggatca
     2581 tctgggtttt caaagtggtc gtattatttt gtatgttcac ctttcctatc tcaagaaaat
     2641 ttagggaggc attgttttat taaagaagct tctctgtatc aataaagaca catttaagga
     2701 aaaactttta aaaatctaat tgggaatttg cccgcataaa taagaggctg tgacaaaagt
     2761 cttgtcacag cctcttattc cgtataaaca gtgttcaaaa gcttgcatct tcgataatat
     2821 gcccaaccaa atgaaaaata tgagaagcta tttttgtttg gctgttctta ttacttgatg
     2881 aagaacagct ttttcacgac ctctttttaa aagtcttttt acagttttcg agcaaagaat
     2941 gatacgatta gtactaaaat gatggcacca atcaatgatg gcacgattgc cattcctgca
     3001 atacttggtc cccaagaacc taataatgct tgaccaagtg ctgatccaac taaacctgct
     3061 acgacatttg caataatccc catcgaagaa cctttattcg tgattgctcc tgcaattgct
     3121 ccgataattc ctccgacgat aagtgaccaa ataaatccca tgtttcgttc ctcctaatgt
     3181 tttacttcct tattactgaa cccgtggttc tgtattttct tttacttttt gtgcgccgct
     3241 tccagctgct gattttactt tatctgtttg attcgaagca aattcaccgg tttttttcgc
     3301 tgcgtcagtt actttgtctt gcaccgtttc ttgatctttt tcaaattctt cttttgtttt
     3361 gatgtccact acgttagcgt tgacttcgat cacttctaaa tgtgtcatat tttttacttc
     3421 tttgccgatt acttcttgca tttcttcaaa gattttttcg atatctttgc catattccac
     3481 aatgacatcc atatcaactg ctacttgttt tttaccgact tctgtttcga tcccagccgt
     3541 tacattatct gtattcacaa gttttcctgc cacattagag aagaaaccac cgtttgcaga
     3601 taataaaccg tctacttgtt caattgcgat tccgatgatt ttttgcacaa ctttatcttc
     3661 ataattcagc tcaccgcgca ttgaatcttc ctgttcagaa tcatgctttc cttggttatt
     3721 tgtatgatca gaaccaagtt ttccttgtcc gtttgtgtgg tcagaactaa gtttttcttg
     3781 tgctttcgca tggtcagaag gatgtttttg ctcttccaca ggtttagaag gatcgattgc
     3841 atcatgttgt tctggaactt tagattctgg agttcctgga tgatgaggtg catgcttttc
     3901 tgcatcatgt ttcttctctt ctactccttg ttgaacgtta gggactactg gatctggatg
     3961 tgcagatact ggtgctgttt tgttcttttc atcgttcaca ccatttgatt ggtttggtgt
     4021 cgttgggtct ggatgtgcag acactggttt ttggttgttc attttattgt tattattttt
     4081 gttattgtta ttcatggatg tttcctccta agatttaaaa tagtgatcta agattttcgt
     4141 ttgtttcaga taaaaaccga tagcgacgcc gatcgctgcc atgatcaaga tcaataaggt
     4201 cttgaaaaag cccacggtga tccataaaac ggctaatatc aatccaagta ccccaaagat
     4261 gatagggagc ttgtatgtcg aaaatagttc tttcattttt ggtccccccc tattctactc
     4321 gtttgcggtc attgcttcgt ttagctggtt cttcaaagcc tgtgtatttc accgatactt
     4381 tcactggctc ttttgttccc aatatgtgtt gtacttcatt ttcgatttct ttcatcaatg
     4441 ttcctgtttt accaatgagt gctgaagttc gtttcaactc cccttttaca ttgacggcga
     4501 tcttgttttt cgttgctttg acatttactt ttggtgaatg gatgaattca tcttcatgca
     4561 agtgagaacg aaccattcct tcaattgctt ttttatccaa cgtcaactcc ccatcaccat
     4621 gtttcagtag aaagtttccg attgtttttg gataaaacag gaaaacaagt aacgtgataa
     4681 ttgtcaaaat agcaaatgca acggcaagcc aaaatacata ttgttgcacg tatgaattag
     4741 tgatggaaaa gaatcgaaac ttctctagct gaaaaggcaa tggataggtt gcacttaata
     4801 gtatcgcaaa caaaagcaca gatagcaaaa gtaatgttcc gatcactccg atcgttttta
     4861 cacctttatt cattttcgca cctcctcata ggggtgaaac gatcaacttc ttataagttg
     4921 atcgcttctc caccagttac tccgtaaatt tgggctgtaa cataacttgc tttattcgat
     4981 gctaagaaaa cataaactgg tgctaattct cctggctgac ctgcacgttc tagtaaactt
     5041 tgctgaccaa attcagggat cgaatcagaa ggttgtcctt cgtctagttg taatggtgtc
     5101 cagattggac caggtgctac accatttaca cggattcctt taggtgcaag ctgttttgct
     5161 aaaccgatcg taaagttagc gattgaagct tttgttgctg cgtaatctaa taaatgttcg
     5221 cttggattga atgcttgaac agaagttgtt gttacgattg ctcctcctgc tgggatatgc
     5281 ggaacagctt ctttcactaa agcaaacata gcgatgatgt ttatcataaa tgtgtctttg
     5341 acttgctcaa gtggtaactc agcaatagac tgacaagaaa tttgctgtcc tgcgtttagt
     5401 accatcgtat ctagcccgcc aagttcactc acggctttat ctatgatttc tttaggtgct
     5461 tgttcgtcac gaagatcaaa aggtagtaag acaatcttac gtcctgcaac tttcacgtat
     5521 tttgctactt cctctgcatc tttttcttct cctgggaaga attgaagagc gatatctgcc
     5581 ccttctctag caaatgcaat cgctgctgca cgaccgatcc ctgaatctcc accagtgatt
     5641 agtacacggc ggttttctag ttgattattg ccttcatagg attcttctcc acaatcagga
     5701 acaggaatca tattctgctg taaagctggt gtatcctgat cttgtttagg aaatttctcc
     5761 gtatggtaca agtttcgcgg gtcgattaat tttggttctg tcattgctgt attcctccta
     5821 gtttttaaat tgtattgcca aaacaaattt ctttgtttga tacctgtttt aaatagattc
     5881 tttaatttgt ataatctttc cggtataaat ggtaacctaa aactactgct gctatcaaag
     5941 agccaaagac tacgagtata aagcctagag cagaactttt acccggtaat cctcctgtat
     6001 tcattcccca aatccctgcg aacaacgccg gaacggaaat gattaatgca gctgaatcta
     6061 gatatttcat gatatgattt agattattgt ccatcatccc gttgaataga tcaccaatac
     6121 tctctaataa atctcgatag atctcgatca ttttttctgt ttgtcgctgt ctcaaatgga
     6181 catcatagag tagctgttca tcgtctaaac gtttgatgaa agtttcagaa ttccataatt
     6241 gatccattgt ttcccgttga tctcttaagg tatgatcgat atatacgatg tctctttcaa
     6301 gatctgcctg tttatacagt tcttcatttt ccgttgtttt acgagctgct ttatccaaag
     6361 cgtcaattcg ctttttcatc tctcttagtt ctttcacgta atgggtgtaa atatctaata
     6421 atgtatacgt gatgatcttt tcaaacgagt ttaaatgatt tccatgcttt gtcagcagcc
     6481 gatccacaaa ttcggttttt ctatcgatac aagtaatcaa gagattatcg gaaagtacaa
     6541 aagatattgg cgttaatttt ttttcgatac gattatctga ctgatctaga ttaatcacta
     6601 ccaaagaaaa tggatgctct agtttcgtct cataaaggcg ctccatccga gaaacttctt
     6661 ccggatattc ggttcctacg aaaatatcat caggaagctc gaattcttcg attgcttgct
     6721 caatctcttc gggctttgca ctatcaagta cgagccaatt atattttttt tcatctgttt
     6781 ctattacatt cttttcttca tccacaaagt agtatctcaa tgtatacctc ctttttggac
     6841 tttctcgaaa ctattagctg aagaagcagt tctttaattt gatattataa tcgagtactg
     6901 cgatttcatt ttctaatgaa aagctgtcaa gctgtttgtt gaagtccatg ttcaatcgtt
     6961 taccgaaata attttgctct aatttagatg tatagatgtc caataatgga tgctcgattt
     7021 tagtcgcata ttctccaaat tccgaaacaa aaggaatgat ttgaaaaaag ctgccttttg
     7081 caaaagcacc tttgtccctt agaaatggat cggaatcatt gataagcgcg agtgcgattt
     7141 ttgtattttc cccaaccttt tcaattaacg tctctactgc atttttagac attgtaattt
     7201 ccattcctac tccccctctt cagttgttgt cttctattat ttaacaacta catctgtttt
     7261 tggttgaact tttgcatatt ttggatattt agggaattta gctacacaac ggaaagccgt
     7321 catccctgca tatttttcgt aatatttctt cgttggccct tcaaaatcct tgctccacgg
     7381 tttcacatgt cctgaaaaat ggataatgta aggattgttg cgagtttctt cgtattcacg
     7441 ttcacctgct gctgttggat gtttttttgc ttttgccatg atatagcctt gtgcattcca
     7501 acgcggatga agtggtaacc aacggtcatg taagatagca tttaatgcat cttggtcatg
     7561 gaatcgtaat ttttctggat tatgttcgat gaaatctaat actttttgcg taatattttc
     7621 atctaaccat tttttcacat tgatcagcat caaacctgag ttgaaataac gcattgattt
     7681 agctgaaatt ttcatttttt ccagtcgttg atggaaccca gcgtcttcaa cagctgctac
     7741 gattgaatca ccgaagtcaa gacgccataa tttagagata tcttgtaaag cgatcatgtc
     7801 gcaatccata tataagatac gttcaacttc tgtgccgcgg aacaattccg gaatcgcaat
     7861 acgataataa gctgtttctg gaatacgatc gctgattacc acatttgtaa agaattcttt
     7921 attgattttc aagaattcca catctgagtt cattcgtgcg tttttcactg agaagcgtaa
     7981 aagctgttta ctttcaaaat cgatatcatc gtcaatcaca tagaaccgaa caaatttaga
     8041 cgggttgcaa ttatctaata ctgagacaaa taatgcagct aaatgtggta cgaattttgt
     8101 gttacaactt gcgactactg ctatttcttt tttattcatt gatctcgcct actttcgtta
     8161 gagtactgtg tgctaatttt tttaagtata aattggtata cggatgatct ttcaacgtat
     8221 tccaaggttt atcatgtcct gtaaagtgaa cgatcgaagg tttttcattt ccttctttat
     8281 actgacgttc atatttttca tttggtgctg gatgacgttc aaaaatcagc gaagtctgca
     8341 tgttccattt tggatgaagt tgttcccaat cttcataaag tacagcattc aaagcatctt
     8401 ggtcgtgata gatgattcga tcgccatttt cactgaggta atggatagtt ttttctgtaa
     8461 tttctttttt attccattga tcaatgtcaa tcaccatcac tcctgaattg aagtacaagt
     8521 catcggaatc gattcctaat ctttccaaag ctttcacttg gcctggatcg ataatagcgc
     8581 cgattgtttt tccatttaac ggctcatcat atagttttac gatatcgtct agtactaaca
     8641 catctgaatc taagtaaagg actttcttat aatcctcttt agctaataag tttggtaaag
     8701 aaattcttaa gtaagcggta gttgtgatat ggtcactgac taggaagtct tcgtagatat
     8761 ctttttccac tgtcaggaat tggatacttg cattacttga atatttattt accgtttctt
     8821 ccaatccttc tttactatat tctgatagac catcgtcaat cacataaaat tttatgcgtc
     8881 ttgttttatt gcaattttct aatgcagttg cgatcatcac gctcaagtaa ggagcataat
     8941 tttcgtctga agcagttacc acaggaacta cgccgtatct cttctccatc aaaatcactc
     9001 ctttttctaa tctttttcta acctgttcta catctagaat attcctcatt tggttttaaa
     9061 gcaaaatata tgctttgttt tcattgaata ttttaaaatt tttttatcac aaaacgcatc
     9121 ggtaagcgct aactattcgt ttttcatggc tttttattca aaggtattga ccaaaaacta
     9181 ctatatatag ccaccttttt cttaagaatg ttttttgaaa aaattcataa tgacaaagca
     9241 agttagtttc atttttttaa attctcattt aatcttaagg taacaggaaa atagatatgt
     9301 aaaaagaaag taggaagata aaatgaaact agcagcgatt gatttagacg gtaccttgct
     9361 tgatcgaaat ggaaagatac cagaagaaaa tatccaagca cttcggaaat ttgatgaaaa
     9421 tggcggaatc gtaaccgtcg ctaccggaag gaacagcatt tctgctaaag atattttttc
     9481 cgaattagga atcggtggct atttgatttc ttccaatggt tcactgattg ctgaaatgaa
     9541 ggatggaaaa atggcgaaag ttctcagacg ttcaaaaata gatagcgata cactgagaaa
     9601 agccttcttc tatgctcaag aagcgaaaat atccatcatt gctagccgag aaacccaaga
     9661 tgatcagctg acattcgatg aatcaaatct agtcaaagat gacccttatt atgaacattt
     9721 caatttacag aaccattctt ttgatcaaat tttaaatatg ttggaagatc cttctcttag
     9781 ctatcttaaa ttagcattaa cagataagag tgaagaaaaa ctacagaagc tacaaagaga
     9841 tctgcaagca gatggtatcc aatcagtatt ctctgatccg catttcttag aaatcacgcc
     9901 tacaggtatc actaaagctc attcacttgt ttttctggcg gattaccttg gaatcgaatc
     9961 gagtgacatc atggcttttg gcgatcaaga aaacgacatt gctatgttga attacagcgg
    10021 gttgagtatt gcgatgggga atgcacagcg acaagtaaaa gaaattgcaa accaagtaac
    10081 actgacgaat gaagaagctg gtgttgctta tattttaaaa aacttctatt aaaaagaata
    10141 aaatgacgat atgaatgtag gaggaaagaa aatgttagtt attattgata tgcaaaatca
    10201 tattcttgat ccaaacagcg aattttatat tccagagtca gatcaattgg cagaacgtat
    10261 tgctcaaaga ttagctaaag cacgccaaaa taatgaatat attctcttca cacgggatat
    10321 accagttgaa ctgaaggaca aagaagaaga acgagaagat ttgcaattga tccctcttct
    10381 ttctccacaa gaaaatgaac gagtgattaa aaagtattac tttacgattc cacctgaaac
    10441 tttagctgaa atccaggaaa ctttatttga aagcaaagaa gaacaaaaag agatcgaagt
    10501 agtcgggatt gaaacaaact tgtgtgtact ctctaatctg ataggcctgc agagtgcttt
    10561 tcctgaagca gacttttttg ttgatccaat gttagtctcc agtagaaaac acggagaatc
    10621 cgctttagag ctgttgaaag atttcaacgt ctctatcgtc gaatcataaa aatatctatc
    10681 ttcatttacg atatttaaca cacaataaaa aaagcacgca gaactgtttt agtcctacgt
    10741 gctttttcta tcaaagtaga ttggcttttt tatgacacag agtgaaacgg caggctcacg
    10801 acctctttct taaatggtgt tcaatcagct gaccctcggt attagcttaa caaacggcaa
    10861 aatatgagga actatttttc cgtttgttaa gctaatactc aggtcaaaac gctgatttca
    10921 caacctcttc cttaaacggt attcaaaagc ttgcatctgc agtaataaga acagccaagt
    10981 aaaaacataa gaagctgttt ttacttggct gttcttatta cttgatgcag ggcagctttt
    11041 tcacaacctc ttatgtacct tgtaggactc gaacctacga ccggacggtt atgagccgtc
    11101 tgctctaacc aactgagcta aaggtacatc ataaataaaa tttatttttg ttacttttca
    11161 actatagcac gaatgacaaa ctctcacaag tttcaaaata taagtaaaat aatattgtta
    11221 ttcttatttc ttttacttgt gtcataacta ttttgttact ttaattttta tttgcttatt
    11281 ttagaaaaaa tgttattctt ttatttattc tcaatgttag gagtgattat tttgccattt
    11341 attgcgattt tattcgattt agttgcggca gcagcttatt ttctccaatt aaattatcaa
    11401 acctcaggaa ttctgtttat tggaatgatt tttcaaggtg tgattaccct tttgcttctt
    11461 gtcatgatgc tcagctataa aggaaaaaga tatgcccgta ttcaaacaaa agtatttgtt
    11521 aaatatgttt ccattcgcta tgggatcatc attctttcct ttttagtgaa tgcgatcgtc
    11581 ctctttttat atgtattgaa ttacttagat atcaatccat tgattttttc tcgatagata
    11641 agacacattc agcggaacag ttcctgctta tcagcagaaa actgttctgc tttttcattt
    11701 ttcattgatc tattcttctt ttattttcct agcatttcat ttgtgatgta tgcaataaca
    11761 tgttatcttt tattatatga atcgttgagg agtccgttac atgattacgt tggtgagagt
    11821 tttgttttgg gtgcctgcgg tcgcactggt cgcaagtatt gtttatctta tgaattggaa
    11881 caaagaacgg ttttatttag ctattttgac tcttccggct atctacttta tgtggaaagt
    11941 ttttaattac aactactttg aacccgatag tgtttttata gaagaattat caggactggt
    12001 tttgtcttta ttgatcgtca ttctttattt gatacgttta aataaaaaac attgagtact
    12061 attgattgca tgtgtagctt tctatagtca ttataactat tctactataa tgaaaggtga
    12121 ttaaatgagt atcgaagaag ctattttact ggatacttta cgttgtcgtc tgaatttctt
    12181 aagaactggc cgatctttat ctcaagtagc tgtttctagc gcgttaagta ttcctttatt
    12241 caaatatcgt aagtacgaag aaggagaaga aattccaagc atcattgaat taatctatat
    12301 cgctgacttt tacgatattt ccgttgatta cctaattggt cgctcagaaa cagcaagcaa
    12361 actgaagtga ttttttccag ccttggtgct ggttttttca tttaacgtct aaggttaaca
    12421 atctatatat aaaggagaca tttctatgcg attatggcat gaaaaattga tttcaaagct
    12481 tcctcgtcaa cagcttttag gacaacatcg ggaatgctgt gcattaagag gaaatggctg
    12541 gggaaagaaa catgctactg tggattatgt ttttcactat tctccttata gattattcca
    12601 atatcatcag cttgtcatgg atgaaatgga aaaacgtggt tacagcccag caccagagtg
    12661 gaaaaatcct atgtatcgtg gcaaatcatg cgaagcattt tttgatttac ctactgtaga
    12721 gcgcaacgtg ccgatttatc cggaacacga tgaagtttat ctagcagaat gtttagcaaa
    12781 tttggagcaa aaaggaattt atcttaccta atataactag aaaagccttc tatctcctct
    12841 tacttcatta aaaagcttta accatcttag atcaagctaa aatgtcgtaa gttttagggt
    12901 tatcttcatc ctcacgtgca aaactaaaag cgtactctag ttttggttca tcgccaactt
    12961 ccctagacat aaatgaacat ctcctgacgt ggtttaaaag taccgcatct tcgacgtctg
    13021 tatacgatgc acagcacaga ttgcttcttt tgatctttct tttgattttt ctgttgcttc
    13081 ttctacacct tcttcgatta ctacatcgat gcttacaatt gcttctgcct aatattccca
    13141 tgcatcgtcg atttaagcct ctgtagtcac tgtgatcgtt tccacatttt aactcctctg
    13201 tcgtggcttc agttgatttt gtgatcagtt cagttgctaa gccagagtca gaacaacctg
    13261 ccattgctag cgttaatatt gatagtaaaa atagtttttt tatcataagg ttccccccct
    13321 gaaaatagac taaaataata acgctttctt tttttgtttt cagacgaaaa ttaataattt
    13381 ctaaatattc tttaaaaaag cttataacta ttatgccttt tttaatatat aacacagtta
    13441 tttttaaaaa taagaatgct aaatcactct acaataacgg cgaaagcaca aaaaataaaa
    13501 aaattattac gttattaaaa aaacagatga aagatcaggt tttattagat ctcattcttt
    13561 catcacttga agggatttaa tgaactactt tttcctcttt gtcgttttta tatattcgta
    13621 ttccttcaaa cagtaggata gcctctttca atgcttgata tttgaactgt ccgttactta
    13681 aaaatttaga tgtgccgccc tcttcctaga acatattctt ttttactttt tcattaattg
    13741 acagaccaat cgaacgaaac tgtaaatttc gataggataa tgattggtca aactcattca
    13801 ttttcaagac atctcgattc atattcaaga taggaatctt tttatcaaca tcactttatt
    13861 cgtattttcc tctaccataa aagcttcacg ctccacaaaa ttgttttata cactactatt
    13921 cagcccattc aacgaccaat gaatt
//
LOCUS       DACBYO010000079        13601 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.079, whole genome shotgun sequence.
ACCESSION   DACBYO010000079 DACBYO010000000
VERSION     DACBYO010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13601
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.079"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(119..1249)
                     /locus_tag="IVD26_002230"
     CDS             complement(119..1249)
                     /locus_tag="IVD26_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP6080164.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            complement(1790..1996)
                     /locus_tag="IVD26_002231"
     CDS             complement(1790..1996)
                     /locus_tag="IVD26_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080165.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(2012..2626)
                     /locus_tag="IVD26_002232"
     CDS             complement(2012..2626)
                     /locus_tag="IVD26_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAP6080166.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(2773..3456)
                     /locus_tag="IVD26_002233"
     CDS             complement(2773..3456)
                     /locus_tag="IVD26_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAP6080167.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(3565..4023)
                     /locus_tag="IVD26_002234"
     CDS             complement(3565..4023)
                     /locus_tag="IVD26_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAP6080168.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(4107..5870)
                     /locus_tag="IVD26_002235"
     CDS             complement(4107..5870)
                     /locus_tag="IVD26_002235"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAP6080169.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(6091..7551)
                     /locus_tag="IVD26_002236"
     CDS             complement(6091..7551)
                     /locus_tag="IVD26_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080170.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(7759..8685)
                     /gene="glsA"
                     /locus_tag="IVD26_002237"
     CDS             complement(7759..8685)
                     /gene="glsA"
                     /locus_tag="IVD26_002237"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAP6080171.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(8708..10135)
                     /locus_tag="IVD26_002238"
     CDS             complement(8708..10135)
                     /locus_tag="IVD26_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6080172.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(10166..11380)
                     /locus_tag="IVD26_002239"
     CDS             complement(10166..11380)
                     /locus_tag="IVD26_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAP6080173.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(11721..11963)
                     /locus_tag="IVD26_002240"
     CDS             complement(11721..11963)
                     /locus_tag="IVD26_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP6080174.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(11995..12552)
                     /locus_tag="IVD26_002241"
     CDS             complement(11995..12552)
                     /locus_tag="IVD26_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP6080175.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(12565..12753)
                     /locus_tag="IVD26_002242"
     CDS             complement(12565..12753)
                     /locus_tag="IVD26_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAP6080176.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(12766..13332)
                     /gene="amaP"
                     /locus_tag="IVD26_002243"
     CDS             complement(12766..13332)
                     /gene="amaP"
                     /locus_tag="IVD26_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAP6080177.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4067 a         2810 c         2221 g         4503 t
ORIGIN      
        1 taatatgatt ttttgagata ctttcattgc gaattcctct ttctaaaaga acctctcgct
       61 tgaaaaataa aagattgtac tttatgataa ttcaaactga gagtttctca gtttctcttt
      121 attgtttttc aggtcgatag agcgccaact cttcggcctg tatctttgaa gaaatattca
      181 acgtgattcc gattcctaaa gaaaggatca gataacttgt tcctccgtag ctaacaaatg
      241 gcaatggcac accagtcatt ggcatcagcc ccgcgatact tcccacgttc attatcgtct
      301 gaacgaatag caaagttccg aatcctaaaa gaaacaatcc agcttgctga tttttacagc
      361 gactgcttaa acaaaagatt ctcatgcata atgagaacaa taagaaaagc acacacaatg
      421 caccgattag cccaagctct tctgtaataa tcgaaaaaat aaaatctgtt tctgtctctg
      481 gaagataccc tttttttgtg atactatttc ctaatccccg cccaaatatg ccaccattat
      541 atagtgcata aaacgaatgg gtcatttgat agcccgcacc atgactatcg ataaaagaat
      601 ctcttaaagt cgcgatcctt tcataagcat gattaaacat ctgtggaagc caacctttat
      661 ttcctaaata taataccccg cctgctgctc caatcagcaa tgcagaaaaa gtaacgatta
      721 gatagatccc ttttttaaat ggaaccgccg ctgcccaaaa tatgacccac gcaatcgaaa
      781 ggatcatcaa tgctccagca atctttggct gaaataaaat cagaaaagtt atacctactg
      841 taatcaggaa tggttttttt agatcttttg ggctactatt tccgtcacga aaaaaccagc
      901 ttaaataaaa aatcaaaaaa agatttgcca gttcagaagg ctggaattga atgccaaaca
      961 gagagatcca acgttgtgcg ccgttgacag tgacaccgaa tatccctatt cttactaata
     1021 ctaaaaagaa aatcgataag gctaaaccgt atcctgctat tttagggtga agtaaatagt
     1081 gtagtttgac tgaacgagct aagaagatca cgctccaact caaaaatatg aaaattagtt
     1141 gacgcaataa tagacttttt gtattttcat cggcttgcaa taaacgataa gaactggcac
     1201 tgtatacttc taaaagaccg atcatggaca aagtcaaata aggacccaaa atccaccaat
     1261 cgatcttttt tcaccgcatc tcctcctcac acagcaatcc acttgtcagg tgaggagcga
     1321 gtttgtctca tcaaataagt cagtcacaaa aatataaaga aaaggtcaga aaccttttcg
     1381 aacaagaatt ctgacctagc atcatctcat cgtccgagtt ttagcactat acaacgtaaa
     1441 gaaaacattc ttagctattg gaaaaagcct taatccaaca gtttctgttt tacccattgg
     1501 cgactttcga cgtttctggg caacagccta tgtttgtata ggagcctcac ctaacaaggt
     1561 tattactata ttctatttac gagttcatga tagacttttc ctaatgatta ggcaatggaa
     1621 tttgaaatga aatagtgaaa tttaacaatc tttaatattt tttagaaaaa aataacaaat
     1681 aagttgaaag aatcccgttg caaattcttt cagttgcacc aggattcttt gataattttt
     1741 tagttttatg tgttttttta tatgtttttt cacttttcgg aataaatatt tatttgttaa
     1801 agtaattaaa caatccgcta atcgtttgat ctggcatttc tatttcctta ccatctaaag
     1861 taacagtagt aacgacaaaa tggtcttgca atggcggaac ttctaagtac tgcccttgca
     1921 gaaaatcatt cactgtttca tattcttttt tcatttcttt tgaatctgtc gatggtttat
     1981 agcttatttt taacataact agtgctcctt tttattcggg acgtgcaatc gtgaaaattt
     2041 ctcctattgc tgcataatca tttcctgcca aacggcttac agcattcaat tttcttggat
     2101 cgatccttcc tgtcttatca tcatagactg tttcatttaa atgatatttc tgtacttcta
     2161 gcaaaaataa atcagctgtt actttatttt tattccgtat ctcgacatgt tcatataagg
     2221 atgtttcaaa acgaactttt gcttctgtca atgctggtac tgaaatgatt actgaatcag
     2281 ttaaagtcaa gtcagtcagg tacagttcgc tttcctcatt aggcagattg gctgctgttt
     2341 tatttacttc ttctacgttg tcctcatcaa ggatatggat aacagcttct cttgtctcaa
     2401 gaatattctt tgctgtgtct tttactgcat cttgttttct ctggatcgcc aaggataaga
     2461 tgggtcgatt cgaactgacg atattgaagt aactgaaggg tgcgatattc actatatctt
     2521 ttgctgattt agtcgttact actgctactg gtctagggat gactgaacca atcagcaact
     2581 tgtaattttc acgttctgtc aattctgaag gactccgttc aaacatggtt tcgccttctt
     2641 tctataaaat tcgttaaaaa gcagatcttg aagacaaaat gaaaagtaat gcttttttca
     2701 tcttcttaga atctgcttta aactatctat caatttttct tttttgtcaa gaatctgtgc
     2761 cgtgcgtgtt ttttagttat ttgctttact tgcggcttcg acatatcttt tagtgatcaa
     2821 ttgcggacgg gtgataatag atccaactac gactgaaaaa gcacctaatt catatgcttt
     2881 ctctacttgt tcaggagagt cagtatgtcc ttccataatt actgggatat cgacttgttc
     2941 tatgatttga ttcaataaat caaaatcagg tgtctgcgtc tttcgtgaat attctgtata
     3001 gcctgctaaa gtcgtagaca aaagatcaaa accatcttct tgcgcttgaa gcgcttcctc
     3061 aaaagtcgaa atatctgcca tagctaaccg accgtgttcg tgaatcattt ggacaagttc
     3121 agcagttgtt ttttctgtcg gacgtttacg agaagttgca tccagtgcaa tgatttctgc
     3181 ttgcgtctcc aaaagttctt ccacttcttt ttctgtcgca gtaataaaca cttctgaccc
     3241 atcgtaatct cttttgataa tccctattac cggtaaatca acgattcgct tgatttcatt
     3301 gatatcttct gtcgtatttg ctcgaatacc aactgctccg ccttcttttg cagccaaagc
     3361 cattctcccc ataataaaag aactgtgtag cggctcgttt tccaaagctt gacaagaaac
     3421 gacgactccg cctttgattt gttccagtgt atccacaata tctcctccag taatgttata
     3481 taaaaataca gcttcatata aaaatgtaac ccttttctat tcaggagaca ataatgagct
     3541 atttctttca gcagaccttt cttactaaaa gaaaattact tcaaattctt cgtatacgac
     3601 cagcttctct tctgtaaatt ctatgttcaa cgcttcttta taagcatgtt taaaaaactc
     3661 agcatggact ttccgccaat aagctaatgt ccgatcccct tctccttctt tccaagcatg
     3721 ctctttcgtg acttcactaa aaggcaagat ggtcacattt atatttttga tgatacaaac
     3781 tggttcattt tttccattca ggaccacgtc taattgacca acttttggta aaggctcatt
     3841 ctcttgttta tacagatcgt aaccacttga tgtaccagtc tttatctttt ttacaactag
     3901 ttcgctcaac tcgtctgcca ttttttctgt atccccaaat gaaaagaaac ctaatttttc
     3961 tgattgataa ctaggatatt tttcttggaa ctttttgaca tattcttcta cttgctgata
     4021 cataacatcc acccctttgc tttttataat gaaaaaacca tccagatact agtataaaca
     4081 attatctgga tggtgagcat aatgaattat tgaatattca agacacgcag actatcttca
     4141 acgatttgtt ttggtgttaa atgataacgt tcataaagct gccctacagg aacgctatcc
     4201 gtgaattctt tctctgcacc aaaatttaat acgttcattg aagaatcacc ataataacga
     4261 ctgatatttt cgccaaatcc tcctgacaaa ctaccatctt ctaatgtgat gactaattcg
     4321 tgtgtttctt ttaatttatc taatgtttct acgtcatttt ctgtgatcgt tcctggattg
     4381 atcaacgttg cttcgattcc tttttttcta aaagctttta ctgtttcttt tcctaattca
     4441 agaaaaccgc ctaaagctaa aattgctact tttcctccat tatttactgt ttgataggct
     4501 ggaatactat aatcatttgc gatagctgta ccatgttcta caccatgtgt aggaattcgg
     4561 attgctacag gctgcgctgt ttgttcgaac gcccaatcta gcatagagat catatcctct
     4621 tttgttgctg gagcaagata tttgatgttc gggatacttg ataagtaagg aatgtcaaat
     4681 gttccttggt gtgttcggtc actagctgag atcgttccgc caccgactaa aataatcact
     4741 ggattctcgt tgatcgctaa atcatgtgat aattgatcat atgcccgttg caagaaagta
     4801 cttgattgga agacgactgg acgtactccc tgagaagcca aagcagaagc gaaagtgata
     4861 gagtgctgtt cagcgatccc cacgtcaaaa taatgatctg gatgtttttc ttggaatgtt
     4921 ttcagtccaa aggcgcctgg tatcgctgca ttgactgcgg caataggagc tgtacttgtt
     4981 tgcattttct tatccaaata atccatgatg atcatattaa atgtttctcc agaagttact
     5041 tgctttgcct ccccggtgga cagatcaaat ggtacatgcc aatgatattt cattttatta
     5101 tcgattgccg gctgataacc gcgacctttt tccgtatgga cgtgaagtac aatcggatga
     5161 tcaatatctt ttacttcttc aaataaacgg atcaccgttt ccagatcgtt tccattatcc
     5221 acgtaacgat aatcaaatcc cattgcttta aataggttat tgctgctttt accgttggtt
     5281 tgacgaagct cagctaagtt tttatataaa ctgccatgat tctcatcaat agacatctca
     5341 ttatcgttta ctaatacgat tagattggat tgtaaaacac caccattgtt caatccttca
     5401 aaagctaagc caccacttag ggagccgtca ccgataaatg ctaccacatt tcctgattct
     5461 ttcttcagat ctctcgcttt agctaaacct gttgctaagc tgatagatgt agatgtgtgc
     5521 cccactgtaa aatagtcatg tttactttca tgttggttgg aatatccgct cacttcacgg
     5581 taatgtcctt tttcaaaacc attttttcga ccagttaaaa gcttatgacc ataagactga
     5641 tgggaaacat cccaaacgat tttatccttt ggtgaatcaa atacataatg aaacgcaatc
     5701 gttaattcta ctacacctag attcggacca acgtgcccac ctacatcgct gtccttttgc
     5761 aagatttttt ggcgcatctc ttctgccaac tgtttcattt cctcaacaga taattttttg
     5821 acatctgcgg ggctattgat tgcatccaat acatgtaata ctgtactcat aatacattct
     5881 ctcctccgta ctatcttctt ttaatgaaaa tagatttgtt acactttatc tattctacta
     5941 cttagagttg actctaagtc aatagcattt taaaaaaatt tcagagaaag cttgttatat
     6001 aagtagatct tcgcacgaat caggactcaa ataaaaacct tctacagaca attaaaaagc
     6061 tttgtagaag gtctcctaat taaggtctca tcaagaaata tgttttttta ataggtgaag
     6121 ttcctgagca atatgataca aatggatgtt tgcacctttt aatgagattg gatagatctt
     6181 tgtcttttca gtttctaatc cattttgata gctagcagca tcgcacaaaa ccactctttt
     6241 tttcgcacat agacattcat caggcaattc ttctaatgaa cgaaataaaa taggatttat
     6301 ttcagcgatg ccttcttccg catacaaatg aaattgggtt cgataaaaaa attgtttgac
     6361 tgaactttct gaaacaacaa aaatttctat ttcctgtctc cccgcttgtt cactgttgat
     6421 caaagaaaga cttttgacga attttcgaat gaaattttca ttccatctta gttggatttg
     6481 atttttcttt ttccactctt ccaatatttc tacaattttt ccgtacagaa gttgttcttt
     6541 ttctgataga agatagatcc tttccggtaa aaatacttgt ccatctgccc acaacgtacg
     6601 gacaaattgt aaaaaggatt gcttgaaaat aaaattttct gcatcgtcga tttcagcgat
     6661 actaataatc tgtaaaatca attcattcag tgataggtca ttgagaacaa aatttttata
     6721 aacaacttcg aaatcttttc ttaacagctc catgttctca ttggtataat ttctactgtt
     6781 gaacaaagaa aaaatataat agacatcttc ttcttgtaag tctagaattc ctttttgctc
     6841 ttccaatcct tgacagacta attgaaataa cggcttcgtt tctgcgcttt tcttatcttc
     6901 ttctttcagt ccaaggggaa atgcctttct tccgattgcg atctctattc ctcgtatgat
     6961 aaaggacttt tcatcttccg aatatcttct tttaaaaaaa tgagtctcta cataatcaat
     7021 caactcgtta caagcttctt ctacatacgg atttttattt tcatagcctt cccaattgac
     7081 ataacgtact aaagctagca agatgttccg cgagtcaaat tctgggataa tgatttcttt
     7141 atttttcaaa taatcatttt ctttaaaaaa atccaatacg atttttttga ttgtatatac
     7201 tttgctcaaa gaaataaatt caagatcagc cagttctgta ctcgtgaata taccattaaa
     7261 ataataactt aaaaacttta aaaaataaga ttgaccgtac agaaactgtg tgagctcaga
     7321 aagagcaata ccatgtttga atacgagttt atacttatgc ttctctctta cttgttcttt
     7381 tatacaatat tctagacact cggctagact ttctagatcg tgaaggatcg ttggtgtagt
     7441 cacccttaga gaaatagctg tttgttcgat gtctatttct tggaattcaa ataattgttc
     7501 acacagatac acttttctaa atatatttcg ctcgatgtaa ttttccagca ttcctgatac
     7561 acgcctccag tttttcttat gattttattt aatcatatct gtaaatcgta tttttgtttc
     7621 ctttttattt agaaaagccc tttcaaaaac caataaaaaa agaaactggg acaaaagtca
     7681 aacaagctca caatttcagc ctcattgtag gtagctttga gccgtttgga cttttacccc
     7741 agcctctttc aagaatggtt attcaaagat gtcagcgtct agttctttga ctacatcttt
     7801 caacaattgg ataccagctg cgctgttacc aaatggatct agtgccgggc tgaagacacc
     7861 tatgccgtaa cgatttggca cagctgccat caacccgccg cctacaccgc tttttgcagg
     7921 tacaccaaca tggacggaaa actctcctga ttcatcatac aaaccagcag ttgtcataat
     7981 tgatttgacg attgtagcac tttcttcagt aatgatttgt ttgccattcc aaggagcaat
     8041 tcctttattt gccagcacag cagctaattt tgctatgcct gtagcggtga cattgaggga
     8101 gcattgtctg aaataagcat cgagtatctc cggtacgtct ccttcgatca tttgattacc
     8161 tttcatatag taagcaagag agcgattgat atcacctgtt cttgattcag aatgatagat
     8221 ttcttcattc aatgtgatat taggatcatc acagatctct ttcataaatg acaagattcg
     8281 ctcaaatttt tcatctgcat ctttaccggc aatcaacgag gttgttgcaa tcgctcctgc
     8341 attaacaaaa ggattcattg gatgtttgcg atgattgatt tccatattca tgatagaatt
     8401 gaaggcaaaa ccggttggtt ccgtgttgat tgtttgaaag actttttcta ttccgttgtc
     8461 tttgattgct aataacaata cgggaacttt tgacatgctt tcgatggcaa agcgcacatc
     8521 ggcgtctcct ccctcaatca gttgttttgt atccaaatca taaatcgcca tacctaattg
     8581 tttgggatcc acttcagcta atgctggaat gtaatccgcc acttgtcctg tttgataata
     8641 gtggaaattt tttccaatca attgttctaa ttcttttact tccatttgaa taaccagctt
     8701 tcatttttta tttttctgca tgctggaatt tatgacggca tgcgtagatc gtaaatggaa
     8761 taactaagac gataagataa gaaacaatca gaatcgtttc ataaatccca tgctgtccag
     8821 ctgcgatact agcaggtgga acaaatgaga tacaaaaagc aaaaagtgaa gtcaaaagac
     8881 ctaaacaagc aacgattact tttacaactt ttccgcctgg aacctgatag gctctttcaa
     8941 gactgtcatc tttaaaaacc agcttcaaat agcccgcgaa aaacataaag tacaacatca
     9001 ggtagattac aacagtcaat gacatcgctg caagaaatga aagattattc cccccgccgc
     9061 ttaatgtaaa gacggctgcc cagattgttg caacgatccc atttgcgatc atcaaatgag
     9121 caggaacacc gtgtgtgttt tcttttgcaa aatattcagg aagtaatcct tcttctgctg
     9181 ctacgtgaag tgcttttgaa ggagaggtta cccaagaagc aatttctccg atgacaccta
     9241 aacaaacaag aatcgcaaga attttcgcaa tccatgcaag atttggatca atgtgtctta
     9301 ataggaattc taacgattga atcacccctg tattaagaga caaaccatgt tgaggtactg
     9361 tagtagcgac ggtcaatccg ccaaaagtat ctaaaatgat tgccagaata accaatacaa
     9421 acattgctaa tggataatcc tttttagggt tttccatttc atttgcatga ctggcagatg
     9481 tttctacgcc catatatgct aaaataaagg aaacaaaaac aaccagcgta ggcaatttcg
     9541 aaaaatcagg aatcaatgtt ttcatagaca gtatcgtttg tagtggagcg cctgaagcga
     9601 cataatggat ccctaagcca aacaagacta atgctggcaa caagatacca gctacaaaac
     9661 cgatccgagc aatcaatgaa gtgtatttgg ttccttttaa ctgtgagagt aaaatagccc
     9721 agaaaataat caataggatt gccaatttca gatatttatt gttttgtata gcaccaatac
     9781 ccgttgcata ggataatgca ccagttaaga aatacagcat ggtcaagtag ccaactgtta
     9841 tctcaaacca ttggaaaaag attgcggcaa aaccgaatcg ttttcccaat gtgcgactga
     9901 cccaagtata gacaccgcct ttttcccatc ctttcaccgt tgccatctct gctgcgcaca
     9961 atgccacagg gataaaccat agcaaaccgc ctaataacaa gaaaaatact aagctgaagc
    10021 ctgaggtcgc gaatgtggga tattcatata atgaaacgac cattgagatg gtcatagcca
    10081 aaaagccaaa gaacgttaat ttttttgcag gaattttcgt tttgctttgt tgcatgaatc
    10141 ttcctctttt ctatttgaat ttgtttcaat tgagtttgtt gccaaagaag aaaaagtcca
    10201 atccttcttc ttgttcttct tttgtagtag tgatcgttgt aaagtgcatc gccgatttta
    10261 aaatcactgt tgtcagcaca taggcataca cggcagtaat gatgacacca atcacttgaa
    10321 tccctaagaa gtaccagctg cttggattcg ttagtaaatg gctgttagat gcaaagatcc
    10381 ctatcagaat cgtacctgtg aatccgccca tgccatgaac accccacaca tcaagtgcat
    10441 catcccattg tttcttttta cgaaaatcaa cagcagcatg acagacgata cccgcaatga
    10501 tcccaatcag catggcactt tttgcttcta cataaccggc acaaggcgta atggctgcca
    10561 atccagcaac ggatcctgtt agtacgtcga caaaatcaaa gccatttcct tttacttttg
    10621 caatgatcag ccaagtaatc atcgcaaatg caagagcgat gaatgttgaa ccaaatgcat
    10681 tgactgcttg ttcatctgct cgaagtgcac caccggaatt aaaaccgaac cagccaaacc
    10741 aaagcagtcc tgtaccgata gcagctgcca taagactgct atgctgactt ctttctccta
    10801 aaggaatctt tctttgacca agtgtgagga tacatgctaa agagccgaat ccagctgtcg
    10861 tgtggatgac tgctccacca gcgaaatctc taaatcccat ctgatccaaa aatccgccac
    10921 cccatatcca gtggcaaaca gggaaataaa tcagcagatt ccaaaaaata acaagtataa
    10981 tatagccttt taaattcaat ctccctgcaa aagctcctgt catcaaagga acggtaatca
    11041 cgataaacat cagttggtaa agaaagaaca ttaaaaatgg aatcgttgca ccatgaaaca
    11101 tgttggggaa gcttgtaaca tgtctcatca aaaagaaatc tgccgggttt ccaataacac
    11161 cgccgatatc ccgtccaaag gccaatccga atccaccaaa tacccacata atcgttgtta
    11221 tcccaacgga gagaaaagat tgagacatga tcgttagtat attattcttc cgtgctaatc
    11281 cgccgtaaaa aaaagctaga ccaggagtca tcaggcaaac cattgctgta cataaaatca
    11341 tgaatgctgt atctcctgta ttgataggta atgtattcat ttttttcgcc tcctttctac
    11401 gattacgagt ataaaagaag gtgtagttgt ttttttcttc tgtttttttg aattaatact
    11461 tgcatttata aaagacagac aattaataaa agcttgatgt gttgtgctct ttttcgtttt
    11521 tcacacaaat aaagacaaaa aataaacggt cttcttttta tagaaaaccg tttattttcg
    11581 tcttttttta tttttaaaga tattttttca taaggaataa agaatacttc atataaaata
    11641 tataaaaaag aaccgcagcg agtgtcgcta cggttctcaa atttgttctt catttcaaca
    11701 taagtttttc ttcaatttgc ttataattta cgtgcaaaga atgaaacgac taatactaaa
    11761 atgattgcac cgatcaatga tggaatgata gccattcctg caattgttgg tccccaagtt
    11821 cctagtaaag cttgtccaat tgctgaacct actaaaccag caatgatgtt tgcgatgatc
    11881 cccattgatg atcctttatt cgtgattgct cctgcaattg ctccaatgat accgccgacg
    11941 attaatgccc aaataaatcc cattttaaat tcctcctaac tgacttctta cttcttattg
    12001 tacacgtggt tcgttatttt ctttgacttt ttgtgcacct ttgcctacag cagattttgc
    12061 tttatctgtt tggcgtgaag caaattgtcc tgtggatttt gctgcttctg ttactttgtc
    12121 ttgtactgtt tcttgatctt tttggtattc ttcttgtgtt ttgatgtctg caacattcac
    12181 attcacttcg ataacatcta aatgtgtcat attgtttact tcagtactga tcaattcttt
    12241 gatttggttg taaatatctt cgatgtcttt accgtattct acgatcacat ctagatccac
    12301 agctacttgt ttcttaccta cttctgtatt gatacctgct gttacgttat ctgtgttgac
    12361 taatttttca gccatatttg agaaaaatcc gccatctaat gtcaatagac catctacatc
    12421 tttcaatgca taaccgatga ttttttggat gactttgtct tcataagtca attcaccatt
    12481 catcatgcgg ttttctcctt tttcatttgc caaaactgat ccatttgttg tattcatgtt
    12541 tttgttttcc atctttgttt cctcctatga tttaaaaaat tgatcaacta ttcctgactg
    12601 tttcaaataa aaaccgattc ctgcgccaat tgctgtcatg attatgatca acaatgtctt
    12661 gaaaaatcca atcgttaacc ataaaacagc tagcagtagt ccaagacccc caaagataat
    12721 agggagcttg tatgctgaaa atagttcttt cattatttgg ccctcctatt ccactcgaga
    12781 gtgcttgtag tctcttgtat cttcttgttc ttcataaccg ctgtatgtga ctgccacttt
    12841 gaccgtttct tttgttccga gtactttagt tacttcttct tcgatatctt gcatcaatac
    12901 acctgttttc cctactaatg aagaagttcg tttcaagtct ccgttgacat ggatatggat
    12961 tcgatttttc gttgaacgta tccgtacttt aggtgaatga atgaactctt cttcgtgtaa
    13021 atgggaacgt accaaccctt cgatcgcttt tttgtcgatt gttagtttgc catcttcccg
    13081 tttcataacg aaagttcctc ttgactttgg atagaaaaga acgactagca agatgataat
    13141 agcaagaacg gcaaatacta cagctgccca gaaaatatat tgttgcatgt agtaattcgt
    13201 taaagtaaag aagcgaaatc gttccaattg ttcaggcata atatacggcg cattgatcaa
    13261 cgcaatcgct agaaatactg aaagtagcag taaactcatg ataacaccga ttatttttaa
    13321 ccccttattc attttccacc tcctataaac ttatttttac cctgtaaata actctaccga
    13381 caatcacagt atagatagcg aacagttagc atagcatcag taaataaagc gctaccaaac
    13441 attgctggat cataacggcg ttttattgcc agtctgatac tgaaataaca attgcttact
    13501 tattctctat ttacttttga ttgctggcta tacttaaagg atattattca agattaaaaa
    13561 ttgcaaagat tatgctcagt tattattaca agattctatt t
//
LOCUS       DACBYO010000080        13232 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.080, whole genome shotgun sequence.
ACCESSION   DACBYO010000080 DACBYO010000000
VERSION     DACBYO010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.080"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(474..1409)
                     /gene="whiA"
                     /locus_tag="IVD26_002244"
     CDS             complement(474..1409)
                     /gene="whiA"
                     /locus_tag="IVD26_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAP6080178.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(1443..2441)
                     /locus_tag="IVD26_002245"
     CDS             complement(1443..2441)
                     /locus_tag="IVD26_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAP6080179.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(2438..3322)
                     /gene="rapZ"
                     /locus_tag="IVD26_002246"
     CDS             complement(2438..3322)
                     /gene="rapZ"
                     /locus_tag="IVD26_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAP6080180.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(3457..4188)
                     /locus_tag="IVD26_002247"
     CDS             complement(3457..4188)
                     /locus_tag="IVD26_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAP6080181.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(4192..5457)
                     /locus_tag="IVD26_002248"
     CDS             complement(4192..5457)
                     /locus_tag="IVD26_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAP6080182.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(5720..8536)
                     /gene="uvrA"
                     /locus_tag="IVD26_002249"
     CDS             complement(5720..8536)
                     /gene="uvrA"
                     /locus_tag="IVD26_002249"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAP6080183.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(8546..10540)
                     /gene="uvrB"
                     /locus_tag="IVD26_002250"
     CDS             complement(8546..10540)
                     /gene="uvrB"
                     /locus_tag="IVD26_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAP6080184.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            10799..12301
                     /locus_tag="IVD26_002251"
     CDS             10799..12301
                     /locus_tag="IVD26_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP6080185.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            12303..13040
                     /locus_tag="IVD26_002252"
     CDS             12303..13040
                     /locus_tag="IVD26_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP6080186.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            13046..13204
                     /locus_tag="IVD26_002253"
                     /pseudo
     CDS             13046..13204
                     /locus_tag="IVD26_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788611.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-binding domain-containing protein"
BASE COUNT         3781 a         2851 c         2303 g         4297 t
ORIGIN      
        1 attactattt atgaacttat gattatcact gaataaatca ctccatcccc ttgttaaaac
       61 ttctacatta attacacctg gttgttttcg actagctaat ccaatgaact tatcaaccat
      121 ccttatccac caaccacgag aatcttgacc agaagtaaga agagcagttc tcaaggatga
      181 tcgagcagtt ccttccagtt ttttaattaa tcaggccagt tatagataaa tacttgatct
      241 tatctatatc aggacttcta tattaagcaa aaatttatgt acaaaactaa aatcttcatt
      301 cagttgtctc cccgcttttt atacgattgt attaaaaaca atagaagcct ttccaaatta
      361 tgttactcca gtaaagatgg aattatagtt tgacggaaga aaagcaagta taacttttaa
      421 aaaaaactga tacattcgca tctcctgctt catgtatcag ttttttcttt ggattaaact
      481 gcttcttcac gcagtttttc cgcaaattca tttattttgc gaattcggtg attaattccc
      541 gattttgata tcgcacctga gggaatcatt tcccctaatt ctttcaagct gacctctgga
      601 tgttgaagcc gaagttctgc gatttcctga agtttttcag gaagggcatg tagaccgacc
      661 tttgcttcga tcaattcgat gttttcgatt tgtttagaag ccgcatcaat cgtcttgttc
      721 agatttgctg tctcacaatt gactagacga ttgaccgaat ttctcatatc ccgtacgatt
      781 cgaacatctt caaatcggag cattgagttg gttgcaccaa tcaatgttaa gaaatcagca
      841 attttttctg ctccttttaa ataagaaata tagccattgc gccgttcaag cgttcgagca
      901 tgtagaccgt aataatttaa catatcgcaa atgtcttggt tatgctgttc ataaatagaa
      961 aatatttcca aatgataacg gctcgtttcc ggattattga ctgaacctga ggccataaaa
     1021 gcaccacgta agtaagaacg cattttttgc gaatttccca taatctcgtc cgaaacgtgt
     1081 ccattgaaca tcataccatc catgatatca agatccatca acacatcttt tgtgccttgc
     1141 ttcaaccgga cgatatagac attgttcttt tttaatttca tttttttacg aacgagtagc
     1201 tcacttcgta cctgataatg atctttcaaa agagaataga tacgtctggc aattgcagca
     1261 ttttctgttt ggacgttcaa aataaactgc tggttcacaa tacctaaaga gccgttcatt
     1321 cgcagcaaag cagctaattc cgctttcgca tgttctcgat gaacttccaa accagttagt
     1381 tctttcttca catctgcagc aaatgacatc ctattctcct cctttctcca acaataaatt
     1441 gcttaatatt ttgaaccgaa aactaaacgg aacaattctt ctactacttt gtctccatcg
     1501 tggaagacac caccatcttt caattccaaa aagtcggtgg aaatcactcg acatccttca
     1561 tttctcaatc cgttgaagtc gtgtgcgact tgtactagat actcatcata gatctctggg
     1621 tccatataat cttcaggcac tttttccgta ttgaccaata ctgtatcgat aaaaggctga
     1681 ttcaaatgct tgtgtaaaac acgtatatga tcggcatctg tgaaatgttc cgtttcccct
     1741 ttttgggtca tgatattaca gatatagacg gtttcagcag ttgtcttgag cattgcttcg
     1801 ccgatttctg gtatcactaa atttggaagg atactggtga ataaacttcc gggtcccaaa
     1861 acgaccatgt cggcgtccat aattgctgaa acgacttttc gagccgcttt ggcttcactt
     1921 ttatcatttg tgttgcagac atacacacgg tcaatggttt tacggtcgat cgcgatttta
     1981 gattctccta ctgcagtcgt tccgtcttta aagacagcat gcaaggtcaa aggagtttct
     2041 gaagaaggat aaacatgtcc atctacatgc atcatttttg ctaataattg aatcgcctca
     2101 taagtgcttc cccgcatctc ggaaactgcg gcaatgatca gattaccgat cgtatgattg
     2161 gctaaaaact gatcttcctt tttgaaacgg tattggaaaa tatcttcata gaattgtggc
     2221 atatccgata acgccactaa gacatttctc aagtcaccag gaggagccat agcgatcgat
     2281 tctctgattg caccgctgct tcccccatca tctgcaacag tcactactgc tgtgatatct
     2341 gctccttgat ttcgcaaact tttcaggata actggcagac cagtgccacc gccgaccact
     2401 acgatctttg gttttcttat ccggtaggtt ttcattttca cgaccggttc accgtctctt
     2461 tccttttatc cttgtcccga tgtgtcacat tgactttata gtttttccct aaagcatttg
     2521 ccaaacgttc agtcaatgcc acagaacggt gttgaccgcc tgtacagccg attgcaactg
     2581 tcaagctgct ttttccttct ttaatgtatc caggcaatac agtttccaga agatccaaaa
     2641 atttatggta gaatgattgc gtttcatcaa aggacatcac ataatcatag actggctgat
     2701 cttttccggt caatggtctt agttccggga tataatgagg gttgggcaaa aaacgcacat
     2761 ccatcacaat atccgaatcg atcggcaacc cgtatttaaa accaaatgat acaaattcga
     2821 tccgaaatcc ttggtctccc tttgatttga atgactcatt gattttttca cgtaattgtc
     2881 gtggtgtcaa tgtcgtcgta tcaatgatca cggaagcttg ggctttcaag tcgtctagta
     2941 tcgcccgttc tttacgtatc ccttcagtga tcaaaccgtc catcgccatt ggatgtgctc
     3001 gtcttgtttc tttgtagcga gccactagtt cttcgtctga agcatctaaa aataagatag
     3061 aagtgtcgat gaagttcgta ttttcgattt cgatcagcat gttttggatt tcttcaaaga
     3121 aggaacgaga acgtaaatcc actcctaaag ccatttttgt gactttgcct gattctttga
     3181 ttaattccca gaattttgga atcaatcgag gcggcatatt atcgatacaa aaatagccca
     3241 tatcttcaaa actttggata gctactgttt tccctgcacc gctcatacct gttatgatga
     3301 ctaattgcaa attatctgtc ataattacga actcctctca cattgtgcat agtaaaatta
     3361 tatcattccg ggcgtatcat taccagtttt ctttttcttt tacaaaaaga tttggaccaa
     3421 atatctttta ggatatttgc cccaaatcca atttttttac ttttccgatg ctgtatccaa
     3481 tgccttgctt ctttcagcta gcgctcgttc aatcgtccga tctgctaaaa tagattgggc
     3541 atcgatcact ggataatggt tatcttcagc aaattcatgc atcaatgaca attctgtgca
     3601 acctaagata actttttcac agtttaggcg ctctaccgct tcttctaaga tttcgtaata
     3661 tagctcttga ttcaaataat ccgattcctt gatctcatga tagatcagat aattgatttt
     3721 ttcttgaaga acagtatcag gaatcactgt ttcgaatcca agatttttga cttcgcgttc
     3781 atagattcca gctttcatac ttccttctgt tcctagaatc gctactctcc ctgtcgtatg
     3841 ctgacggaca agttcatttg ctgcttctct tggcatatga aggataggaa tatccgttgc
     3901 cgcttgtaat tcttcaaaaa agtagtgtgc ggtgttacaa gtcaacacaa tgaagttcgg
     3961 ctgcaataaa ttttgtttct caatatcatc cagcagaaac ggcattggat tttcttctga
     4021 tcgatctaaa atataagctg tacgatcagg aactgttgca tgattgaata agacataatt
     4081 caaatattct tgatcttttg tagctttcgt tcggtggttg atcaagcgaa caaaactttc
     4141 tgtcgccatc gtgcccattc cgcctaaaat actgaaaaaa ttctccatga actagccttc
     4201 tttcacatga aaatactttt tgaatcttgg aatatagtta tggaacatat atttcatcaa
     4261 caaccagcgc ttgattgacc ggtctttttc ataaaacaca gtagtaccgt aacgattttc
     4321 tttgatcatt tgctcagcta gttttttgtc ttcattttcc cgagcatatt ctaaaaagat
     4381 ttttttgggc acacccatcc ataatcttgc tttatctgat tgattcgttc cataggtcgt
     4441 ttcaacaaag ggtttgttaa acactcgatc ttctgtgacg aaacgagcca gattcaagcc
     4501 gttcaatgtc acaaagaaac tgctacgacc ttgtctcaaa ttgatttcaa ataatttata
     4561 ttctccatct ctaggatcat acttcatatc gaaattggca aagcctgtat attcgatttt
     4621 ttccaaaaat gccttaatgg tttgatagat tttttcgtta taatctggca tgatcacaac
     4681 gtaattacca atcgatgctg gtgtaggatc ttctaacagt ggatgaccaa gacacatcat
     4741 ccgaacttga tgatcttcat ctacatacgc atttagcaca cgcatattac tatcatcacc
     4801 cgggataaaa tcttgtacaa tcatttcact tttataaccg gcttcgtata tccggcctaa
     4861 aattaaatcg aactcttctc tagtctctaa aataaaagct ttttttcttc cttcaaattg
     4921 gacagaaaga tactccacac tgtttgcagg tttcaaagca actgggaatt caaaaggcaa
     4981 ttcctgttcc aaatgtccat ttactaacat ttcttctctg acgatcaatg ttttaggata
     5041 cggaagatca tattcttcac aaacttcata aaagcttact ttattgatca gtctttcaaa
     5101 taaagaataa tcaatatatg gacagataaa atattctgac agctcttgtt tatgttggga
     5161 gatcaattct gcatatccat caccacaagc aatcaaaaga tattttttac tcttatcaga
     5221 atatctttct tttgccaaac gaagcatcgt ctcgataaac acagggtctt tatcaaatcc
     5281 tggaataact tctacattga caattttact gtagcgggta ggggctaact gatccgaagc
     5341 atatgcttgg cagattttgc cgtatgcttc attaaaagaa cgtgccatac cataaacgtt
     5401 catgtcgctt cctaataata tagggataaa ttcttcattt tcaatactgt tcatcattat
     5461 ctctcactta ctcataatct cttgtttttc ttttccaact acacaaggaa tatcatacca
     5521 taaagaaaaa agcaatcaaa ggaaactcct ccgattgctc aattcttttt tgaacggatt
     5581 gaacttatag gaagtttttg tctataccaa tcagtgtaga aagaactacc atgtaatgat
     5641 tctagaacac tgatattaat aaaacaagca aaaattcatt tttttatgtt tttttaacta
     5701 tctcagctat ctatcctctt tataccatta tttttttcaa atagtgacct gtataacttt
     5761 cttttacgtt aatgatttct tctggtgttc cagtcgcaag gatcgttcct ccaccttctc
     5821 caccttctgg tcctaaatca atgatataat ctgctgtttt gattacatct agattgtgtt
     5881 caatcactaa aactgtgtta ccagcatcta ctaatctttg taatacatgc aacaagcggg
     5941 cgatgtcatc gctatgaagt cctgtcgttg gttcatctag tatatagaaa ttctttccat
     6001 tagagatttt gtgcaattca ctggcaagtt tcatccgttg tgcctcacca ccggacaatg
     6061 tcgttgctgg ttgccccatc gtcacataac ctaagccaac atcaacaatc gtttgcagtt
     6121 tgcgatgaat ctttggaatg tgcttgaaga attctacagc atcttctact gtcatttcca
     6181 aaatatcagc aatgcttttt cctttgtaat gcacttctaa tgtttcagag ttatatcgtt
     6241 tgccatgaca tacttcacaa ggaacataga catcaggcaa aaagtgcatt tcgatcttaa
     6301 taattccatc cccgcgacaa gcttcacaac gaccgccttt tacgttgaaa ctaaaacgcc
     6361 ctttcttata accccgcatt tttgcctcgt tcgtttgagc aaataaccca cggatatcat
     6421 caaatacact tgtataagtc gctggattac ttctcggcgt ccggccgatt gggctttgat
     6481 cgatatcgat gatcttttcg atactttcgt agccggaaat tgtcttgaat ttacctggct
     6541 tagcagaatt cttatttaat ttttgcgcta acgatttctt taagatacta ttgaccaatg
     6601 tactctttcc agaaccagac acacctgtga ctgctacaaa ttctcctaat ggaaattcaa
     6661 cactaatatt tttcagattg ttttctgaag caccagtgat cttgattgct ttcccattac
     6721 ctttacggcg ttcttttggt acagggattg attttttccc tgaaagatat ttccctgtca
     6781 aagaattttc atcattagct acttcttcag gagtgcctgc agccacgatt tgtccgcctt
     6841 gttctccggc cccaggtccg acgtcaatca gataatctgc tgcccacatc gtatcttcat
     6901 catgttcgac tacaacgagg gtgttgccaa gatcacgcat tttctttaat gagccaatca
     6961 gtcgatcgtt gtcgcgttga tgcaatccga tcgatggttc atctaaaata tacaaaactc
     7021 cagaaagatt cgatccaatt tgtgtagcca atctgattcg ctgcgcttct cccccagata
     7081 atgttccgga agcgcgactc aaagttagat agtctagtcc cacattttcc aagaatgaaa
     7141 gtctgtcatt tacttctttt aaaatcggtt tggcaattac tttctcttgt tcagataacg
     7201 ttaagtttga gaagaaatct actgcttttt gaatagacaa ctcatttgtt tgcccgatat
     7261 tcgttccatt gatttgaaca gatagagctt ggggattcaa tcgataacct ttacatgtct
     7321 gacaagttaa ttctgtcata taaagacgca tttgctcacg cgtgaaatca ctgttcgtat
     7381 catgataacg acgctcgata ttcttcaata ccccttcgaa agtcgtttct acatcgcgaa
     7441 cgccaccaaa atcattttca taatggaaat ggaaaagatc atctgtccca ttcaagatga
     7501 tatcctgatg ctcttccggt aattcttcga atggtgtatc taaatcgata ccgaaacttt
     7561 cacaagcctg cgctaacatt tgaggataat actgagagct gattggattc catggaacga
     7621 tagcaccttg actaagtgtc ttcgttctat ctggaatcac taaatcttga tcgacttcta
     7681 atttgacacc taaaccatca cagtctggac aagctccaaa aggcgcattg aatgagaaca
     7741 gtcttggttc tagttcgcca acagtaaatc cgcaataagg acaggcatag tgttcgctaa
     7801 acaacatttc ttcttcaccg atcacgtcaa ccagagcata gccgtctgcc aatcgcagag
     7861 ccgcctctaa agaatcaaat agacgagaac gaatcccttc tttcacaatg atccggtcga
     7921 tgacgatcgc gatatcatgt tttttgtttt tctccagctc aggcacttca cttaaatcat
     7981 agatctcacc atcgactcga acgcggacgt atccctcttt ttggattcgt tcgaatattt
     8041 ttttatgttg tccttttttc tttaccacga tcggtgccaa cacttggatc tttgtgcgct
     8101 caggcaaagc cattacttga tctgccattt gatctactga ttgactggta atctcgatat
     8161 gatcgttggg acaaatcgga tgtcctacac gtgcaaacaa caagcgtaaa tagtcattga
     8221 tttccgtcac agtacctact gtcgaccgag gatttttact tgttgttttc tgatcaatag
     8281 aaatcgccgg actcaatccg tcgatgctat ctacgtccgg cttatccatt tgtcctaaaa
     8341 actgacgagc ataagcagaa aggctctcta cgtatctccg ctgcccttca gcgtacagcg
     8401 tatcaaatgc tagggaactt tttccagaac cggacaaacc tgtaacgacc acgaatttat
     8461 ctcgtggaat cgttacatct atatttttca agttatgggc acgtgcaccg tgaatcgtaa
     8521 ttttatcgtt agccatgttg tcctcctact ttgaagcttt taattctaaa atcatatctc
     8581 gcacattagc ggctgtttca aaatccaatg ctttcgccgc atttttcatt tctttttcta
     8641 atttcatcaa taacgtatct ttttcttctt tcgtcatttc ttcatacgag acttgtaccg
     8701 cttcttttgt atcatcttcc gattctttcg taatagaaat caaatctcgg atttctttaa
     8761 tgatcgtttt tggaacgatc ccatgttctt cattgtactt ctgctgaatc gtacgacgtc
     8821 ttgacgtttc atccatcgct agacgcatag aatctgttac tttgtctgcg tacatgatta
     8881 ctttaccttc ttcattccga gcagctcgtc caatcgtttg gactaaggaa cgttcactac
     8941 gtaaaaagcc ttctttatcc gcatccaaga tagcaacaag ggaaacttca ggtacgtcta
     9001 atccttcacg aagcaaattg attccaacta acacatcaaa ttcacctaat cgaagatctc
     9061 gaatgatttc tgttcgttcc agcgttttga tatcactatg caaatatttg actttgatcc
     9121 ctaattcttt gaaataatct gtgaggtctt ctgccatttt tttcgtcaat gtcgttacaa
     9181 acacccgctg gtctttttcg actcgttcat ttatttcgcc tactagatca tcgatttgtc
     9241 ccatgattgg acgaacttcg atcactgggt caagcagccc tgtcggacgg atgatttgtt
     9301 ggataacggt atctgtttgt tcatgttcat atggtcctgg cgtcgcagag acataaatga
     9361 tctgattgac atgtttttca aactcttcta accgaagtgg ccgattgtct aaagcagatg
     9421 gcaaacggaa accgtaatct actagcatct gttttctcgc tcggtcacca ttatacattc
     9481 ctctgatttg aggcatggtt acgtgcgatt cgtccgccac gatcaaaaaa tcttcaggaa
     9541 agaaatccaa tagcgtataa ggcggttcac cttctttacg tccgtccata tgccgagaat
     9601 aattttcaat tcccgacgtg tagcccattt ctaacatcat ttcaatatcg taattggttc
     9661 gctgttctaa acgttgagct tccagaagtt tgttttcatt tcgcaagaca gttaaacgct
     9721 gttctaattc cgctttgata ttcgctacgg catgctccat atgttcatca ttcgtcacaa
     9781 agtgagtcgc cgggaagatt gctacgtgtt ccgtttctcc taaaacttca cctgtcagtg
     9841 cattgacttc tcggatacgt tcgacctcat ctccaaaaaa ctccacacgt aaggcacgtt
     9901 catctcttga agccggaaaa atctccacga catcaccgcg cactcgaaaa cgaccgcgct
     9961 gaaaatctat atcatttctt tcgaattgga tactgactaa gtcacgaatc aactgattgc
    10021 gatctagttc tgctccctgt cgaatcgaaa ctacttgttt ttggtactca aaaggcgagc
    10081 ctaatccaaa aatacatgaa acggatgcaa tgacgatcac atcatttctt tctaataatg
    10141 aactagtagc cgaatgtcgt aatttgtcga tctcatcatt tacacttgaa tctttttcga
    10201 tatacgtatc gcttgaaggc acataagctt caggctgata ataatcataa taagaaacaa
    10261 aatattcaac agcattgtta gggaaaaatt ccttgaattc cccgtacagc tgaccagcca
    10321 atgttttgtt atgggcaata atcagtgttg gtttattcac tttctcaata agattggaaa
    10381 tcgtatatgt tttccctgtt ccagtcgcac ctaataagat ttgtgctttt ttcccgccga
    10441 ctacgccatc cactaattgg ttaatcgctt caggctgatc accagccggt tggtatttcg
    10501 agacaagctc aaagtgtcgg gaggtatctc tctcaatcat tcttcgtcct ccttttcatt
    10561 cattcctttt cattttacga ccaataaaaa gaaaaggaaa gcaaaggcat tccttactaa
    10621 aaaattatac cacaccgaac atactttcgc cactttttta tcttattata catgttatgt
    10681 tttataacat aaaatgttag aaactcgcat ttttttcatt ttttcgagct tacagtcttg
    10741 tctgattcag cacttttcgc ctataataat aaaatattgg aaatttagga ggttgattat
    10801 gaaaagaaag catttatttc actcatttgt tttcttaatg acaggacttg tgacacttgc
    10861 gtttggtcat gttgcacaag ctgacaacac tacaacggca gagtcaagca caagcgagac
    10921 aatgcaaaaa atagagccca aaaaagacgt atacgtaatt gccagtgact ctgcttttgc
    10981 tccatttgaa tttcaaaacg caaagggcga gtacgaaggc atcgatgtaa aattgatgga
    11041 aaacatcgcc aaactgcaag gatttaacat ccgaatggac taccgtggtt tctctgctgc
    11101 tttgcaagct ttggaatcag gacaagcaga cggaatgatt gccggaatga ctgtaacaga
    11161 tgaacgaaag aaaagctatg atttttctga ttcttacttt gatagcggga tccaattagc
    11221 tgtcaaaaaa ggagatactt cgatcaagtc ttatgaagat ttgaaaggaa aaacagtcgg
    11281 agcaaaagtt ggtaccgaaa gtgctgaatt tttaagcgac catgaatctg aatatggcta
    11341 ttctatcaaa tattttgatg ctgctgatca attgtacgac gggttaaaag ttggcgcaat
    11401 cgatgcaatg atggatgatt atccggtaat cggttatgcg atcaaacaag gacaagaatt
    11461 ggaaacaccg atcaaaaaag aatctggcgg aaaatatgca tttgccgtta aaaaaggaca
    11521 aaatcctgag cttcttaata tgttcaatga aggattgaaa gaattaaaaa gaacaggcga
    11581 atacgataag attattaaag aatatgtagc ggatggttca gaaacttcca gtgagtcttc
    11641 cactgctgat gaatcaacat ttcttggact tatccaaaac aactatcaag cattgttgaa
    11701 aggactttgg agaacaattc tcctaacttt gatctccttt gctttggcta tagtaatcgg
    11761 tgtgattttt ggattattca gtgtagcacc aatacgcgct cttcgcacaa ttgctagtat
    11821 ttatgtcgat atcatccgag gaattccaat gatggttctt gcgttcttta ttttctttgg
    11881 gttgcctggt atcgttggat ttacgattcc tgacttcctt gctggtgtta tcaccttgac
    11941 tcttaacgca agtgcttata tcgcagagat tgttcgaggc gggatcaacg ccgttcctgt
    12001 cggacaaatg gaagcttcca gaagtttagg tctttcttat aatcggacaa tgcaaaaaat
    12061 cattttgccg caagcgatac gcatcatgat cccatcattc gtcaatcagt tcgttatctc
    12121 attaaaagac acaacgatca tttccgcaat cggtgtagtc gaattgctgc aaactggtaa
    12181 gatcattgtt gcacgtacaa cacaaagtac gtatgtttac ttgatcattg cgatcatgta
    12241 cttgattttg atcacagcat tgacaaaatt agcaaaagtt ttagaaaaga aggtgaagta
    12301 agatggcaga aaaaatctta gttgagcatt tagtcaaaaa atacggcgat aacacagtat
    12361 taaacgacat caatgtatcc atcaacgaag gagatgtcgt ctgtatcatt ggcccttcag
    12421 gttcaggaaa aagtacattc ttgcgttgct tgaatcgttt agaagaacct tctgacggtg
    12481 aaattattat tgacggcgcc cacttgatgg ataaaagcac agatatcaac ttggtgagac
    12541 aacatatcgg aatggtattc caacacttta acctattccc tcatctttct attttggaaa
    12601 acatcatttt agcaccgatg gacctgaaga aagaatctag agaagaagca gagaaaaaag
    12661 caatcaaatt actgcagaca gttggtctag aagataaaaa agatatgtat cctgaaatgc
    12721 tttctggtgg acaaaaacag cgtgtggcta ttgctcgtgc tctagcgatg aaccctgaca
    12781 tcatgctttt tgatgagcct acttctgcac tcgatcctga aatggtcggt gatgtcttga
    12841 acgtcatgaa aaagttagca gaacaaggta tgacgatggt tatcgttacg cacgaaatgg
    12901 ggttcgctaa agaagtggcc aatcgcgtca tgttcattga cgacggaaac tttttagaag
    12961 atggaacgcc tcaacaaatc tttgaaaatc cgcaaaatga acggacaaaa gatttcttga
    13021 ataaagtatt aaatatttaa aataaattat atatgtcttt ttgactatct ttttatatct
    13081 tcttaaatgt ccgcaaagcc ttattttata ggctctacgg gcattttgct tttgtggtaa
    13141 acctcacata tctaggtcta tcttcttata ttttcactat caagcgtggt taaaatcgtg
    13201 gtaaatactt ctatgcaatt agacgctgaa cc
//
LOCUS       DACBYO010000081        13052 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.081, whole genome shotgun sequence.
ACCESSION   DACBYO010000081 DACBYO010000000
VERSION     DACBYO010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.081"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            421..975
                     /locus_tag="IVD26_002254"
     CDS             421..975
                     /locus_tag="IVD26_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP6080187.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(1148..1621)
                     /locus_tag="IVD26_002255"
     CDS             complement(1148..1621)
                     /locus_tag="IVD26_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP6080188.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1633..2169
                     /locus_tag="IVD26_002256"
     CDS             1633..2169
                     /locus_tag="IVD26_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP6080189.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            2209..2580
                     /locus_tag="IVD26_002257"
     CDS             2209..2580
                     /locus_tag="IVD26_002257"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP6080190.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            2864..4135
                     /locus_tag="IVD26_002258"
     CDS             2864..4135
                     /locus_tag="IVD26_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HAP6080191.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            4380..5405
                     /locus_tag="IVD26_002259"
     CDS             4380..5405
                     /locus_tag="IVD26_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6080192.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5699..6808
                     /locus_tag="IVD26_002260"
     CDS             5699..6808
                     /locus_tag="IVD26_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP6080193.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            6891..7787
                     /locus_tag="IVD26_002261"
                     /pseudo
     CDS             6891..7787
                     /locus_tag="IVD26_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378728.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            7803..8627
                     /locus_tag="IVD26_002262"
     CDS             7803..8627
                     /locus_tag="IVD26_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002579255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6080194.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8659..9969
                     /locus_tag="IVD26_002263"
     CDS             8659..9969
                     /locus_tag="IVD26_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HAP6080195.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            10117..11376
                     /locus_tag="IVD26_002264"
     CDS             10117..11376
                     /locus_tag="IVD26_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP6080196.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11386..12258
                     /locus_tag="IVD26_002265"
     CDS             11386..12258
                     /locus_tag="IVD26_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6080197.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYCLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            12270..>13052
                     /locus_tag="IVD26_002266"
     CDS             12270..>13052
                     /locus_tag="IVD26_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6080198.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLA"
BASE COUNT         4409 a         1929 c         2510 g         4204 t
ORIGIN      
        1 acaaaattat gatcttgcgt aaagttataa aatattaata aaaatatttt attaatgaaa
       61 agcttggtag cacggttatt catatgctaa tttatttcac tttatagtaa ggggagttct
      121 tagtatattg ttcaaactta aatttcatat aatttaatta tgtaaattag ctattctaag
      181 aacttctacg gataactgcc cgtctaaaat ttaaataaga gcttagaatc ttcatataag
      241 taaggttaat ttttttgtac aaaaaagtcg gaatattctg agttactgaa atgatataaa
      301 atcataaact aaatcccttg attttattga ctttcaaaag tttatatata taagttaatg
      361 attatggtaa aatatataca taatcattaa ctcagaatat ttttaagaag ggaaacaata
      421 gtgagctata atgtacaacc gttaaggaca aatgaagaga tacaagattt tcagttttgg
      481 ctaagaagaa caagtaatcc ggaaagagat agttttttat ttttgtttgg aatcaataat
      541 gggttacgta tgtcagatat tataggatta aaagttggag atatacgagg caaaagtaag
      601 cctattattg ttgaacataa aacaggtaag cgaaaaccga tttttataga taatttgaga
      661 gaagaaattt tattatatac tgaaggtaaa gaagaaaatg attggttatt tccgagtcgg
      721 caacaaggtc gacatataac aagggatcgt gtctatcaga tatatgcaga tatagcagaa
      781 aaattaggac gagatgatat aggaacacat acattaagaa aaacttttgg gtatcactac
      841 tacaagaaaa ctagagacat tgctacctta atgtttattt ttaatcatag ctcgcaagca
      901 attacaaaaa ggtacattgg tataactgaa gatgaaatag gagcatcact tcgtggattt
      961 aaactaggtg tataatttaa aaatttttat aaacagtaaa gacaaagatt aaaagctatt
     1021 tttatctaga acgattttat ttcataaagt tcgcggaata aaagctgggg ttactggtac
     1081 ttggtatagg ttcgtgttat ataaactaag taattaaata acatttttag gttggaaaag
     1141 gatgaaatta aaaaaagaga atcaatacgg tctcaaaaac gcaaacgctg cggaataaga
     1201 aaaatactga taactcaacg tttagcagac tatctaatag ggatagtctg cttttttcgt
     1261 ttttgaccat acttttgacc ttctgcaaac ttccttgctt ttcctctgta gaactcatga
     1321 aatctgcaaa acgaattgcc gtttcctctg tctgcttttt cgcgatatgg gtgtatatat
     1381 catccatagt ggttttaata tctgtatgtc caagtcgaac atacacttct ttgacagacg
     1441 caccagattc aaagagcaga ctacaatggg tatgacgaaa accatgaagt gtgatatgtt
     1501 ttaagttatt ctctttaatg atgattttca aattgtgatt tacatagtct aaataaaggg
     1561 gcttattttc ttctgatgaa aacaaaagtt gttcaccatc ttttataggt ttgattctca
     1621 tttttagata ttatgcccgc acgtattcat cacatttcta ttgtgaatcg ctttattcga
     1681 ccgacatttg acttttatca taatatactc ggtttaaaat tactaatgaa aacaattaat
     1741 caagacgatc ataccatgta tcacctgttt ttttcagata atcaccaccg tgtgggaact
     1801 gaactgactt tttttgaagt acaagaaggg aacaaccagt tttttggaac caatacgatt
     1861 gaacgaacga tactaaaagt tccttccgaa gcatcattgc atttttggga aatatatttt
     1921 gaaacacaag gcgtttgcca ttatggaatc gaatcatttt ctggacgacc tatcttacgt
     1981 tttgaagggc cagatgcaac acgattagct ttagttccct tacgcgaatt tgaagatatt
     2041 gatgattatt tcccgtatgt cacagaccag atccctacag agcatgccat tttaggaatt
     2101 gatgccattc aactacgcgt acaatattcc gatgcgactg aacgagagtt attgtcggta
     2161 ggctggtagc acaaagaata cgtcagtttc ttttcgggtc atcaacgagt gacaatctta
     2221 gaaaatcaag acactcagtt ctatcaagaa gttcagatta ttcaagatcg tgagaatcca
     2281 gttgccattg aagggattgg tagcgtccat catgttgcgt ttggcgtaga aaataaatct
     2341 gatttacaac gcatcgacaa acaattacaa gagcgcaatt ttataaattc aggaataaaa
     2401 gatcgtgaat tttttgtatc actttattat cgtgacccaa atcaattatt gattgaaatt
     2461 gctacagggg aaggaaacct agatgcaaaa gcgtatgaaa atcaaagtcc acgctttgaa
     2521 gaaattcctt tatttttacc gcagtactta aatttcattc gtgaacaagt ggagcaataa
     2581 ttagctaatc aaatccatga cgaagagtaa gaggttgact cataagtcaa aaaataaaga
     2641 aaaacgcatc aaatccattc taaagaatgt tgatttgatg cggttcctat ttttataaac
     2701 tatcattttc gactaataaa actacttatg agtcagcctc tctttttttc ttgattttta
     2761 tacctctttc taggtaaact aaacatctgc caaaaatacc gtgtctcatt gaaacattct
     2821 caactatttc aaaataaagg ggagtaccaa atgaacgagt atattgaaat tatccacgca
     2881 agagaaacaa cttaaaaatg tcagtctcaa aattcccaaa aataaaatta gtatttttac
     2941 cagcgtatct ggttcaggaa aatcatcgat tgtttttgat actattaccc aagaagctgg
     3001 tcgtcaactg aatgacacct atgatagttt tacccgttta tttttaccta aatacagtcg
     3061 tccagaggtt gatgagattg ataatctttc tacggcgatt gtggtcaatc aaaagaagat
     3121 tggtggcagt gcgcgctcaa cgttagggac gattactaac atcaatgcgt tatttcgtgt
     3181 gttgttttca tgttttgcaa cacctagttt aggatatgca aatgcttatt catttaatga
     3241 tcctagtgga atgtgttctg tctgtcaggg aatcggtaag acgattgcat ttttaatagg
     3301 attgctttat ttttcggcta ttgataatgc tgattttgta ttttctgatc catttaccgc
     3361 agaagttttg tctggaattg aggaacaggc aaagaatcat ggttattttg tattggtgca
     3421 taatgttaat tcagcagaag atgttaaaac tattcagaga aattggcgtt ttgaggggtt
     3481 cattgttgtt ggtgtacgtg taaaagaatt tttggaatta aataacgttt ttgatggtcc
     3541 tgttgtttat attgatacgc atctttcaaa agagacatta agagaacttg aacaacaaat
     3601 gaatcgttta tttgtaaata caaatgatta ccaagctagt acattggcag tggaacattt
     3661 gattcattat ggtcatgaga aaatagcgtt tctttctttt gactacattg taggtgaacc
     3721 aagtgttatt caagaacgac atcaagctta tatcgataca ttaaagaaat atcatttaac
     3781 ctttaaatcg cattggatat ataacaactc tgaatttgag cgaatttatc aagaattagc
     3841 tgaatttact gcaattgttg ttactggaga ttatttagcg gctaaattag taaaattttt
     3901 aaaaaataag aataaacgag tgatggaaca attatcgatt attggatttg atgatattac
     3961 ttttgcagaa ttaatggatc ctgcgttgac aacaatacga ctaaatccag gtaacaaggg
     4021 ggcgattgct tttcaccaac tgattggact ggccaaacaa gaagaaataa aaaatcaagt
     4081 actactatta gagggagaat tgatttctcg agactctgtt cacaaaatca aataaaaaag
     4141 ctctgtgaaa taagtatagt taacaataaa atatccgaac gatagagaga atgaactgtg
     4201 atctagcagt tcctcgtcgc aaattcacta gaattagcat tatttactct aaattgttcg
     4261 gatatttttt cttgttttta attatgatta cagtgcctat ttttaacgaa atttgcttat
     4321 tttcaaaatg tatgattata tgttagtaaa cactttcaaa tatgaaaaga ggagctatta
     4381 tggtaggaat tagggatgtt gcaaaacggg cgggtgtgtc cattgcaaca gtatcgcgcg
     4441 tgctaaatga ggatccgaca ctttcagtaa ccgatgaaac caaacgaaag attgcagaat
     4501 cggttaattt ttatcattat gtcaaaaaaa gtcccgttgc aaaaaattta acaaatattg
     4561 cattaataac gacagtttct gaagtagatg agttggaaga tccctatttt cgaacgattc
     4621 gcagagggat tcaagtcgaa gcagaacaaa gcaaagtcaa tttgaagaaa attattcgtt
     4681 tgtcagaaac accgttggag caagacgatt tgctaaaatg tcaaggtgtg ttgattattg
     4741 ggcaggtgct atcttctgtg attgaagaag tatcagcaat taattcgaat gtcgtagtga
     4801 ttgatgaccc tagtattgaa gctgaagtag atgcagttta tactgattta acaaaagcaa
     4861 cgaatcagca tttagatcga ttgtataaaa aaggacaccg aaacattgcg tttatcggag
     4921 gaggacgtgt tcgtttagat agccaaggaa ataaacacgt gtcagatgat gattatcgaa
     4981 aaatagccta tgagacgtgg atgaaacaaa aaggattaga aaaatatagt caaatttatt
     5041 tagaaggctg gaccacactt gacggaatgc aggcagcaga tttacttttg aaaaaacatg
     5101 ctaaagataa gttgccgact gctatcatgg taggaaatga tcctattgct gtgggggttt
     5161 atcgttcact tcaaaaaaat ggtctacata ttccagaaga tatttcgatt gtgagttttg
     5221 ataatattga agttgctgaa tttttaacac ctgcattaaa tacggtgaat gtgaatacag
     5281 aagaaattgg aaaactagca gttcgcatgg ttaatgaacg aataaaagaa gttagaaatg
     5341 tttcgatcaa agtgattgtt tctaataata ttattgttag agaaagtgaa aaaaatatcg
     5401 attaaaaaag taaacatcca aaaaagggtg tttacttttt tgtttactaa tatttttagt
     5461 aaaaaatctc gacaaaacat taagtaaaca gttatggtgt tgttaacaaa aagaaaacgc
     5521 attcaaaaca ggaggaatta agatgaaaca tttcaaaaaa atagctttaa cagggatagc
     5581 tgttttaact gggacattac tcgcagcatg tggtggggga gatagtaatt ctaaagacgg
     5641 gcaagtaact ttaagctatg cgagttgaga tactgaccaa gctccaggac taagaaaaat
     5701 gttagatgaa tttgaaaaac aaaatcctga tatcaaagta gaaatggaga caacgccttg
     5761 ggatcaatat tgggttaaat tagaagctgc aacaacggga ggtaatatgc cagatgtagt
     5821 aaccatgcac tctagcgaat cctataaata tatgtcacag aatgctttga tgggacttga
     5881 tgatgttatc aaagaaaatg atattgacat gggaaacttt actgaaggaa ttgctgattt
     5941 ctatacgctt gaagacgaac tatacgcaat ccctaaagat gcttctgtag tggggctatg
     6001 gtacaacaaa gaattatttg ataatgcagg tgtcgattat ccagatgaaa catggacatg
     6061 ggaaacactc agacaagctg caattgattt aacagatgaa tcaaaaggca tctatggttt
     6121 tgcatcacat attggaacag agactggcta ctggccattt atttatcaaa atgggggaga
     6181 agtatttgcc gatgacaata caaaatcagg tttgaatacc ccagaagcac aagaagcttt
     6241 agctttttat cgagatattg cacttgttga tcatgcttca ccaacaatta cagaattaca
     6301 agatcctgat aagttaagtc gttttcaatc aggtagatta gcaatgatga ttgaaggaaa
     6361 ctggtttgca ccgggatttt tgaaaaatga ctatctagtt gaaaatgttg cttctgccgt
     6421 gttacctaag ggaaaagtta atgcaacaat tacaaatgga cttggttggg ctgccagtgc
     6481 gagtacaaaa tacccagaag aagtgaaaaa actaatggca tttttagcta gtgaggacgc
     6541 caataaaatc caagcggaaa cgggggcatc aatcccagca ctaaaaggct ttgaagacga
     6601 gtgggctgct tcttcagata caattgattt gagtgctttt ggaaaaatgt tggagtatgg
     6661 agtccctcgt ccatacaata aagatggatt acgagctgaa caagcagaag ttcaaattat
     6721 taaccgtatt ctgtctggtg aagtaactgt tgaagatgga accgctcaaa ttgaaaaaga
     6781 agtcaatgcg atattgagcg gaaattaaat tagttaatta tacaatatac aggcgaaagg
     6841 attctatttc gtctgtatat taatggatga ataccaaaaa gggggatatt atgaaaaatc
     6901 gaatttttgg aaaatatcgt aaagatcaag tgatatgggg ctatattttt atttttccaa
     6961 cggcattagg attaatttta ttaaatatat ggccagcaat tcaaacagca attttaagtt
     7021 ttcaaaaaac ggtagggttc ggtgatactg aatgggtcgg attaagaaat taccaaaaaa
     7081 tgtttgcaga cggtgaagtt tttcagtctt tattaaacac attaatttat gcagtggttt
     7141 cgatacctag tattgttgta ttatccttgt tggtggcagt tttaatgaat agaaaagtta
     7201 aaggattgtc gatttatcgg acaatttatt ttctaccagt cgttgctgca ccatccgcag
     7261 tcgcaatgat ttggcgctgg atgttcaata atgattatgg actgattaat aacatgttgg
     7321 ctaaaatagg tctcgatgga ccagcatggt taacggatcc atcgattgcg atttattcta
     7381 ttatcattgt aggagtttgg agtgctattg gttataacat ggtgttatta ctagccggct
     7441 tataagaaat tcctaaagat tattatgaag cagcggaaat tgatggtgct agtccaatcc
     7501 agcagttttt caacattacg ttaccattag ttacaccaac attatttttt gtagttgtaa
     7561 caacagttat caatgctttc caagtatttg atgttatttt tatgatgatt actcctaata
     7621 gtaccgccat gtttaaatca caatcattag cctatttatt ctataaacat tcatttattt
     7681 taaatgacaa gggatatggt tcggcaatcg ttatgttcct tttagtgatt atattaatta
     7741 ttactgcaat tcaaatgaag ttgcagaaaa agtgggtaaa ctattaagga ggctatcaaa
     7801 ttatgaaaaa taaatttttt tcaaatgcgc caatccatat catgcttatt ttaggtggta
     7861 ttgcaatggc attacctttt atttggatga ttttaacttc agggaaaacg ttggttgaat
     7921 ctacccaaat tccacctaca attttccctg agaaatttca gctaagtaac tatcaacaag
     7981 tacttgattt attaccattc atggcttttt atatcaatac atttttaatg gttgttggac
     8041 gagtgattgg ctcggtttta ttttcagcaa tggctgcata tgcttgtgcg cgtctaagtt
     8101 ttccagggaa aaatatcctt ttcagcttag tacttattca aatgatgatt cccggttcca
     8161 tttttattac tccacagtat ttattagcac aaaaattggg tattttaaat acaattccag
     8221 cattaatatt accaggggta gttagtgcgt ttggtacgtt tttattaaga caatttttct
     8281 taggtttacc tgatgaattg gaggaagcgg cctatttaga aggtgccaat atttggacga
     8341 tctttttcaa aattatgttg ccgcttgcta aatcaggatt ggttgcactt ggaatattca
     8401 cagcgttgtt tgcatttaaa gatttaatgt ggccattgat tgtcaatact tcaattgata
     8461 agatgccttt agctccggga ttagcaaact tacaaggaca atatgccacg aacttcccac
     8521 aattaatggc aggttcgtta ttagcaattt ggccaatagt tgtgatattc atcgttttcc
     8581 aaagaaaatt cattgaagga attgctacaa caggtagtaa attataaaac tattaattag
     8641 tgattggaga gtaagtacat gacaaaaatt acatttattg gtgcaggaag tactattttt
     8701 gcaaaaaacg tattaggcga tgcgatgtta actccaagtc tacaagatgc acatattgca
     8761 ttgtacgata ttgatgaaaa acgactaaaa gaatcaaatt taatgcttaa aaatattaat
     8821 aaaaattcga atgaaaatcg tgctgatatt gtttcttatt atgatcgcaa agaagcgtta
     8881 agagaggctg attttgttat caatgctatt caagtgggtg gttataaacc ttcaacagtg
     8941 attgattttg atattcctaa aaaatatggg ttgcgacaaa ctattggtga caccatgggg
     9001 attggtggga tttttagaac cctacggaca ctaccagtaa tgttagactt tgctaaagaa
     9061 atggaagaag tttgtccaaa tgcttggtta ttgaactata caaatccgat ggcgatgtta
     9121 accatgggtg ttttaaaagc gacgagtatt aagactgttg gtttatgtca tagcgttcaa
     9181 gtatgcgtac cagaattgtt tgagcattta ggaatagccg atcaatatga cttaaatgac
     9241 tttcaatgga aaattgcagg cattaatcat atggcattct tgttggaaat tacaaaaaat
     9301 ggggaagatt tctatccaac aattcgtcag ttagctgcag aaaaaccaaa tccacatcca
     9361 gattctgtac gttttgaatt gttgaaacgt tttggttact atattacaga atcaagtgaa
     9421 cacaatgcag aataccatcc atactttatt aaatcaaaat acccagaatt gattgacgaa
     9481 ttagggattc cgttggatga atacttacgt cgttgtgaac aacaaattaa tgattgggaa
     9541 agcatgcgag aggacattgt aaataatggg gagttaacac atacgagaag ccgtgaatat
     9601 gcttcatata tcatggattc tattacgaca ggaactccgt cagtgattgc aggaaatgtc
     9661 ttaaataaag gcttaatcac aaacttaccg acagatgttt gtgtggaagt accttgttta
     9721 gtcgataaaa atggcgtgca accaacctat gtcggtgaat tgccaacaca attagctgct
     9781 ttaaatcgga cgaatatcaa tgttcaagaa ctgacagtag aagccgcttt aacactagat
     9841 aaatcaaaaa tttatcaagc agcgtattta gatccacatc tatcatctga attgtcttta
     9901 acagatatca aaaatttagt ggatgattta atcgaagcac atggggacta tttacctgaa
     9961 tataattaaa aagaagctga aagagtaagg aattttcaat tccttactct tttcttagtt
    10021 aaatttagta aaaatattga caaaacactt agtaaacagt tacattagtg ttaacaaaaa
    10081 gaaaacgcat tcaaattgta taaggaggag cataaaatga agtggtctaa aaaaattatt
    10141 ttagcttgta tagcactagg agcaacgatc tctttgactg cttgtggaaa aaatcaggaa
    10201 gatgcaagcg gtaaggtaga aatagagttt tttaatcaaa aaaaagaaat gactcaaacg
    10261 attcaggaga ttgctaaaga ttttgaagca aaaaaccctg atattcatgt aaaagttgtg
    10321 gatgtaccga atgctggtga agtaattaaa acacgtatgc ttgcaggcga tgtaccagat
    10381 gtcattaatc tttatcctca aagtatagaa ttgaaagaat gggcgaaagc tggttattta
    10441 gaggacttaa ccgaagaacc gtatttagag aatatcaaaa atggatatgc acaacgtttt
    10501 gctattgagg atcgtgtata tagcatacca ttaaccgcta atgtctatgg tttttactat
    10561 aacaaaactg cttttgagga aatggggatt caagcaccag aaacttgggc agaatttgaa
    10621 aaaatagtag ctgagattaa agatcaaaac aaagtaccgt ttgcgattgc aggagcagaa
    10681 ggctggactt taaatggtta tcaccaacta gctatagcga ctgctgctgg tggtgaagag
    10741 gaagcgaaca atgtttggcg tttctcagaa gttaatggaa ttaatgctga aagcaaagaa
    10801 atgcaaaaag attttaatcg attagatttg ttaagagaac caaaagcttt gcaaaacaac
    10861 tggcaaggtg ccggttataa cgatacagta gttactttta caaaaggtga tgcgttgatt
    10921 atgccgaatg gttcatgggc aatgccgatg attcattcac aaaatccaga ttttgaagta
    10981 ggaacttttc cttttccagc agatgaagca ggtcaaagtc taacgattgg cgcaggagac
    11041 ctagccttat cagtttctgc aacttctcaa cataaagaag aagccaaacg ttttgtagaa
    11101 tatatgacaa cacctgaagc gatgcagaaa tattatgatg tagatggtgc accgtgtgct
    11161 gttgagggcg ttatcgagaa tactcaggat tcaccattaa gtggtttaac tgaacttgct
    11221 tttactgatc gtcatttagt ttggttagcc aaagattgga atagtgaaaa tgatttttat
    11281 accttaacaa caaattattt acacaatggc aatcaaaaag ccatgattaa cgcattaaat
    11341 gctttcttta atccaatgaa agctgacgga aggtaggaaa ataaaatgaa aataaaagaa
    11401 attttaaatc gttactgggc aatcattttt gtagcaattc caattatttt gcagatgatt
    11461 tttttctact ttccaatggt tcaaggtgct ttttacagtt taactaattg gactggtctg
    11521 acttataatt ttgattttgt gggtttgaac aattataaga ttcttttttc tgatccgaag
    11581 tttatcaaat cgattggctt cactttaatt gtgacgcttt gcatgattgc tggacaaatt
    11641 ggttttggta ttttgattgc gcgggcgttg aacgcaaata ttaaagggaa aacattcttt
    11701 agagcatggt tcttttttcc agcggtctta tcgggcgtgg ttgtttcttt agtatttaaa
    11761 caaattttta actattgttt accaaaaatt ggtagtatgt taggcattga atttttacaa
    11821 accagtcttt taggaacaac atggggagcg atttttgcag taatttttgt tttactttgg
    11881 caaggaattg ccatgccagt catcattttc ttagcgggtt ttcaaagtat tccacaagaa
    11941 attattgaag ctgctagaat ggatggggcg aatgataagc aaattttttg gaatattgaa
    12001 atcacctact tattaccaag tatttcaatg gtatttatta tggcattaaa aggtggctta
    12061 acagcatttg atcaaatttt tgctttaact ggtggtggac caagcgatgc cacaacatct
    12121 ttggggttac ttgtttataa ttatgctttt aaaaacaatc agtttggtta tgcgaatgct
    12181 attgctttag tcttatttat cttaattggg attgtttcac tggcacaatt aaaattatcg
    12241 aaaaaatttg aaatctagga ggtttcccaa tgaaaacatc aaaagaaaaa aatatttcta
    12301 aatacttgct tttattatta gggggcttca tgattttagt tcccttagtt tcaacgctat
    12361 tcggttcatt taaaacaaca cccgatatta tgaataattt ctttcgtttt cctaatccag
    12421 cgactttgga aaatttccga agattgttag cggatggaat tggtcattac ttttggaatt
    12481 cggcaatcat cacaatcatt gcagtagttg ctgtgacagc aattattcct atggctgctt
    12541 attcactagc aagaaaaatg actcgtggga aagcatacgg attgatgtat ttatttttaa
    12601 ttttaggaat ttttgttcct ttccaagtaa ttatgattcc gattaccgtt atgatgagta
    12661 aaattggttt agcaaatatg tggggattaa tcttactcta tctcacttat gccgtaccac
    12721 agacactatt tttatatgtt ggttttatta aactaaatgt gcctatcagt ctggatgagg
    12781 ctgctgaaat tgatggggct agtcacttta caacttattt caaaattgtt ttcccaatgt
    12841 taaaaccaat gcatgcgacg actattattc ttaatgctct atggttttgg aatgatttca
    12901 tgctaccatt attaatttta aatcgtgatt ctaatatgtg gacactacca ttgtttcaat
    12961 ataattatac gggacaatat tttaacgact atggtccaag ttttgcttcc tatacagtag
    13021 gaattgtcac gattacacta gtttatcttg ct
//
LOCUS       DACBYO010000082        12885 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.082, whole genome shotgun sequence.
ACCESSION   DACBYO010000082 DACBYO010000000
VERSION     DACBYO010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12885
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.082"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..3081)
                     /locus_tag="IVD26_002267"
     CDS             complement(<1..3081)
                     /locus_tag="IVD26_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP6080199.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFE"
     gene            3338..4729
                     /locus_tag="IVD26_002268"
     CDS             3338..4729
                     /locus_tag="IVD26_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP6080200.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(4802..5449)
                     /locus_tag="IVD26_002269"
     CDS             complement(4802..5449)
                     /locus_tag="IVD26_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6080201.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(5457..6143)
                     /locus_tag="IVD26_002270"
     CDS             complement(5457..6143)
                     /locus_tag="IVD26_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6080202.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(6149..7222)
                     /locus_tag="IVD26_002271"
     CDS             complement(6149..7222)
                     /locus_tag="IVD26_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP6080203.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            7444..8118
                     /locus_tag="IVD26_002272"
     CDS             7444..8118
                     /locus_tag="IVD26_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6080204.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            8123..9463
                     /locus_tag="IVD26_002273"
     CDS             8123..9463
                     /locus_tag="IVD26_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6080205.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(9612..10598)
                     /locus_tag="IVD26_002274"
     CDS             complement(9612..10598)
                     /locus_tag="IVD26_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAP6080206.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            11322..12353
                     /locus_tag="IVD26_002275"
     CDS             11322..12353
                     /locus_tag="IVD26_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP6080207.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            12462..>12885
                     /locus_tag="IVD26_002276"
     CDS             12462..>12885
                     /locus_tag="IVD26_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAP6080208.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT         3876 a         2371 c         2274 g         4364 t
ORIGIN      
        1 ttcgaataga aaggtatctg tttcttgtcc atcttttggc gattctaagt ccatttctgg
       61 tccctgcagt ctgaattttg ctccttttaa tgtctgtccg ttgtcttctt ttttgtgtac
      121 cgttagatca aacgctttta gtcgattttg atgagtgagc gtccatacat tatttgtcat
      181 ctcggtattt tttcccgtgt aaatgatttt tccatattta tcgatttgga attcataatt
      241 tcccggcgaa gtatcatatc cggcaggacc agctgtttca acgactcgat atttaccagg
      301 tgtgagtgaa tcaaaactgg caagaccttt ttcattcgtt gtttggctgt caattggctg
      361 ataagtacca tttgcttctt ttttctgtag ggaaaatgct gctcctttaa gatttatctc
      421 tttgtccgtc ccttgcatcg catacttacg tactgctaca ggaacttcaa caaaaggatt
      481 ttcaatagtc aactggatcg tatcatcgga agtagtgact gtttttccat caatggttac
      541 cgtaccatca gaagcgatct tgatttccca agtagtcttt ttgcttaatc catgcccttc
      601 tggagctttt gtttctgtca gcgtataggt catttctttt tgcaatttga cattttctgg
      661 aagagaatag gttccgtcgc catgatctgt tagtaaagta tcaatagaat ctcctgttaa
      721 tttgaaaaca gcgccaataa gatccttttc acctgtagag gaatttttcg ttattttcaa
      781 gtttaacggt gtgaattgtt tagtattttt ccatgtcatt gcatctattt gttgagaatc
      841 gtatcctggt acaggtaatt ctttgattgt ttggtaactg aatgcttgac cttgattatt
      901 gtattgaggt agtgataata tctcttgata actttctccg ctatttgcag ataatttgtc
      961 aatgtctgca cgttcccacg tatttgttgt atctttagct ggtttaatga ttcgaatata
     1021 tccgtttttc caagctgcag catttgtcgt atgttcccgt tgaatctcaa aagtaacttg
     1081 atctggacga tcagctagat tgttgtcaaa ttcttcccat aactttttga tgtgaagact
     1141 gactccggga gctttagcag atggtatacc gaattcagct aattcattgg tatcaatgtt
     1201 tggctggaaa gttgtcctgc cgttcatttg ataccagaaa tttggatgga agtcctcatt
     1261 ttctgtttgg attctcactt ggtaatggat ttggatttct tggtcttttc ctaaatagat
     1321 ctgattgctc ttgatggtat ttccttctat ggaaatagat ggagtgaccg ttgtaggact
     1381 tgtccccaca ctcttgactg aaagtgtacc aggctgataa atgaatggtt ctgcgattgg
     1441 atcatttatt tgtccattgc ttacagttgc tgagatctgt acagcttttt tggctaggta
     1501 ttcagagata tctgttgcat gatcagctga ttcatagtaa agatcgcctt tttcatctga
     1561 tgaaaccatt tgtcgcatac gagactctac ttctgctttt gagagaccag ctgccggatc
     1621 gctttgaagt tggatgccaa gaccatgtat ttcgattcct cgttctttga gtgccatcgc
     1681 ttctccgatg gttgcgataa acgtactgtc gattcttctg gatagattgt tttggtcagg
     1741 tgcatcatag attcttgaga ttagagaagt atttcccggc cgatcttgcg tattagaaaa
     1801 ctgagttccg taataattgc tgcttgattg tgcgtgtacc cgctgtactt tataggaaaa
     1861 tgttggtaca ccatccgtca gcaaaacgat cactttttta tgtccatttg gaacggatag
     1921 catgcttcct gcatctctta gtgctttttg tgtaaaagta ccaccatttg tccgtgaagg
     1981 tgtaatggat tttacttgat ttttcactga atcaaatgaa cccatctgta ctgcaccgtt
     2041 actgtagcta tatccttcgc ttgagtagcc gacatatccc atattgattt tgtctgtgat
     2101 accgctatct gctaaagtat cgacaaaacg atcgacacca atctttactt caccgatccg
     2161 attattgtcg ttcatacttc ctgaccagtc tacgaccaat acgagatcaa gaggcgtgat
     2221 atctttttgt acatttccac gagcattcaa ataaacatca aacaatccgg gtgtacttgt
     2281 ttcctttgca tactttcgta tcgcatagtc tgcttgatta ccggttcctc catattcgat
     2341 atacgaatgg gtccgatcat taggatctcc attccaagaa tttataccat cccattgatt
     2401 tgttccgttt ttattgcctt gatgatcaag aacatttgta tttcctgtag gttgccaact
     2461 ggctttagga taagtgccct gatcatctgt tgtatattct gtaggaatcg tttgattaga
     2521 tggcacactc acagctggca aggataatgt aggcaatgta aatgggctga cagaattttc
     2581 gttttctttt gatgattctt cttctatttc gtctggcttt ggtactgaca catctgtatc
     2641 tttcttattt tctgtctcat caataatgtc atattcttta ttatcgacga tcagcttgtt
     2701 tgcctggctg tggtaaagtg ctggatcgat tggaaaactc agatcgatag tttgtttagt
     2761 gtttgatgag atttccaacg taattttccc gctatttacc tgataagcat agccatctcc
     2821 ttcttttctt tccacatcac ttaagtaatt ttcgactaga ccaatttctt tttctatctt
     2881 ttcagcactg gtgttattcg catttagctt gatgttcagt gctttttttc cagactgatc
     2941 cgaaatgact tcagctgaaa ttgtttctaa aactgttgga tcatctgtag tgtctgctat
     3001 tgcagataat ggcacaaagt ttgataaact caatattatc agcatgaaaa taactttcag
     3061 tttcttccct gtggtcgtca tttttcccct cctttttctt tttttctgtt ttgacgtgaa
     3121 tagtgaaaat tattaaaata aacaggcgtt acataatttt atttatttta atatgataat
     3181 tattatacga agggcgctaa agggaatcac accaattttc ataccaattg gtttcattta
     3241 tgaagttgat tccttcgatt aatgagcgtt tcattgaaag aaaagggttg agggagaaaa
     3301 acatatgatc aggttgttgg aattaaacta tagaaagatg gaaaaaatca ttcgaattct
     3361 gtccatttct gacaagtgga tgactaaaaa agaacttgcc aaacgaattg gtagttcaga
     3421 atctacattt gtaaggtata tcgaagagat caaaatccgc tggggaacgg atgtaacgat
     3481 tcaatcttca caaaaattgg ggtatcgtct tgaacatttg aatgtaccag cttatttaaa
     3541 tgttctgatg gaaatgtcgc aaagttctac aaacagtcgt ttattaaatg agattattgt
     3601 caatccgggt aaaacgattg agtattattg tgaaaaaatt tccatcagcc ggtcttcttt
     3661 tacacgtaag ttgaaacaat gcaatcaaat tttagaaagc tatttattaa aagtgatcgt
     3721 tgaccaaggt tttcagttaa ctagccttaa aagtgagctc cagttgcgta tctttgttac
     3781 ctttttcttt ttaagttact acggaagacg cacgttgcca tttccaatcg aaaaaaagaa
     3841 gatcaaagaa attatggtca agaataattg tcagatgaat ttgtttcagg aagaaagccc
     3901 atatgagcaa tctttcttta ttatgtattt tgttgtgcat ctcatgagag aatcccaagg
     3961 aactccattt gaatggaaag ctggagactc ttatgtacag ttgataaata tcgataaaaa
     4021 agacttctta atcttgaaaa atctcttagg aaaattgaag tacagcagct atataaaagt
     4081 agtgaactat tttgtcaata cgattttttc agaattttcg gagaaagaaa aaaatgaaat
     4141 cagtgagcag atacgaaaaa atatgtccta ctgttcgttt tcatccgctg attgcaaaga
     4201 aaaaaacgaa gaatatgttg ttcaattatt aacgcaaatt tattttttct cccgtatttt
     4261 cccatacgat acgactcatt tgacgatccg tgcaacttac tttgcacagc agatgcaaca
     4321 ccgccagata cgtctatatg ctggatttcg tgcagaactt caattttatt ccactctact
     4381 gaatcagaat ctgatttatt atttatctag ctatatcttt tggatgctta tcggtaatcc
     4441 tgaaattcac cattatactt ctgataaaaa aatactgatt atcagcgact taagtcttcg
     4501 acatagtcaa tatattgaag aatatatcag tgatattctt gctgtgcata aaattcactc
     4561 tgagacaact gctattactg aagatcagct gtcgaaatac aatcttctcg agtatgatct
     4621 gatcgttacg aatcaaccca ttttgaatgc ccatgttcct catatattga ttgatgatag
     4681 tgtgtcattc gcaaatgaag aagaactcat ccgcttattc gagttatgaa taatcaaaaa
     4741 acagctatgt ataaaccacc ctgataaaaa tttcaggaca aatacacata gctgtttctt
     4801 tttattgtat tccttcagca atccaacgag atttatagcg aaagtctttt aacaactctt
     4861 cttttgtcca attatttgca atgagatccg tcaaagtgtt cattacgagg gtcatggaaa
     4921 agtataggaa actaactgct tcttccgacg attgaatgga gaaatgattg attcttaata
     4981 attccagcca tttttcgttc attggagaat cagccgatag ttctctacgt ttggttgtct
     5041 gctgatcatt tcgctgggtt aacaagtata acctttgcca atagatactt tcgtgatcta
     5101 agtcgcagca ccactctaaa tatttttcga tccccaaaaa gaaatgttgt ttgttttcgc
     5161 taatgaattt taagatatct tgatggacta tgtgagaact gcttttgatc gtatacaaat
     5221 aagcatcttc caaatcttga aaatatttat aaaaagcacc gcgcgacatc cccatcttgt
     5281 caacgatttc tgagactttg acttggctga tgtgctgtga gcaaaatatc tccagtaata
     5341 ggtcatcgat tctctgtttc tttgcgttcg ataaattgaa aaaagtttct tttggcatcc
     5401 acatctctcc tttatctctg attatacgtg gatagccctt cattgtcatg aaggattcat
     5461 tccttctttt tctcttcttc tgtcaagtac ccatcttcca ttcgataaac gcgatcactc
     5521 cattgaatca tacggacatc atgagtaacc ataatagtcg ctttttgttt ctcatgagct
     5581 tctttaacta gtaatttgac gacttcatat gcatgatctg tatccaaact agctgttggt
     5641 tcgtctgcta agatcaagct tggctcatta tataaagcgc gagcaattgc cactctctgt
     5701 ctttctccac cagaaaggtc tttaggataa ctatttttaa gtgactggat atctaaagat
     5761 tgcagcaagg aatcgatttt tgttgaatct tctttttttg aagtaacttg gtcaactagt
     5821 tcaaattgtt cctttaccgt taaaaaagga atcaaattag agctttggag aataaatcct
     5881 atttctttaa agcgtaaatc tgctcgtttt ttttctggaa gctcagttag tgagtgaccg
     5941 ttgatcacta tttctccgga agtcggtgtt tgcaatcctc ctgaaatggt aaggaaagta
     6001 cttttacctg aaccagaagg accaatgatg ctgacgaatt ctccttcctt tacataaaaa
     6061 tcaattgctt tcaaagctga gacctttgta tgaccagaac caaatgtttt ggtaactttt
     6121 ttcatcgtta atattttttt catttttatt aacctcctat tgctgtaatt gggtctactt
     6181 tggttatcgt acgtatcgaa aacaatccgc ctagcattgc gacaatgatc aaaatcccac
     6241 tatatagcaa ccattgtgac caaaaaacag caaaaggcat cgcgcttggt aaaatcagac
     6301 tagtcaaata agcaaacaaa agagcaagca gaacgcctac caccccaaca ataaaggact
     6361 gtgctactaa agatttagcg atgaagaaat ttttgatccc ttgtgctttc attactccaa
     6421 aaatagcagt cttctgaagt gtcatcacgt acatgaaaat accgaccacg gcagcaacca
     6481 ctaagaacaa aaagtatatc atcgcattta aggtcatatt ttgggcagaa tagccaggaa
     6541 tactttcaat gaatgtccca atagttaata actgtagacc cttcgatgct ttttctttcg
     6601 aaattttagc tgaatccttt attacgatcc cattgatcgg ctgttcttct tcagaagcaa
     6661 acggctgttg tccatacttc aaagcagtcc acgtatctag ggacgcatag atgacgggag
     6721 aaactgtgta ataagtttca ggaaagatac cgacaatcgt caaaggatcg tcgtaactgc
     6781 caattttgat cgtatctcca attttatagc ctgaatcagc cagattttga gagatgatga
     6841 tttcattctt tgttttaaat tcatgccctt tcgtgagttt tggtaataaa aatgcttctt
     6901 tcgttgtgcc gaaaactgta acattttctt tgttttttcc tttgattgct ccgctgtaca
     6961 atccgattgg tgctttctct cctccttcaa tgtatttcag atctcctctt gttaattgtg
     7021 aagctgcaaa tacttgattt gcatcctccg acaaaacaat ctcttgtgcg tcccaatcat
     7081 cgattgcttt tttaaactct tctgaaagtc cattcgctag tcctgacaac atgaatacga
     7141 catacgcaat caagaacata ataccgacga tcaagccata tcgtaattta gaatagcgaa
     7201 tttctttgat agctagaaac atttgttttt cctccctatg atagattgat agtgacaaaa
     7261 tgtcacttgt tgaatagtgt aactctaaag tgacaatttg tcacttgtgt tgtttttttc
     7321 ttatcaataa attgtctaag acatctttcg ataaaacctt aacatgagtc ataaaaaatt
     7381 tatttaagcc ttatttatgc tttccatgat aaactaaagt gaccaaatca atgaggtggg
     7441 aaaatgatta aactattagt agtagaagac gataaagtat tatccaataa tataaaagaa
     7501 atactcgctg caatcggcga gataacacaa gtttatgatg gtagtgaagg actgttcgag
     7561 ttggaaagtg gagtttatga tcttgcaatc ttggatttga tgatgccgga aatgaatgga
     7621 tatgaagtgt tagcaaaaat acggaaagaa aaaatacaga ctccagtatt gattttgact
     7681 gcaaaagata gtttggaaga taagattgaa ggatttgaac gaggtgcaga tgattatcta
     7741 acaaaacctt tctatcgaga agaactgatc atgcgcgtga aagcattatt gaaacgctcg
     7801 ctaggtctct ttgatgaaaa tgttctgaag tataaggata tcagttgtga tttaaaaagc
     7861 aatgaagtct tgtataaaga acaagttttg cccatacaag gaaaagagtt tgaattgctc
     7921 gtttattttt tacaaaataa gggaatcatt ttgacaaaag agcagatatt tgaccggatc
     7981 tggggatttg attctgatac gacgattaca gttattgaag tttatatgag caacttacga
     8041 aaacatctgc gaagtactgg attggataaa gaaatcaaaa ccttacgtaa tgtcggttat
     8101 atactgcaaa gggtgtgatg caatgaatgg agatattaca cgaaagcaac gtagtcgctt
     8161 ttttgcgaca aatgtagcag catttgcttt tatctttttt cttttgggat tcattacttt
     8221 acagatatta aaccaatctg catacagaga aacagatctg tcattagaga aaataaattt
     8281 tgattctcga acagtacaat tagagataca aagatatcag caaggcgatc cctttttaaa
     8341 cccgactcaa acggaacaaa acagaacaaa catggaacag ccattaatgg aaccatcaaa
     8401 tgaccgtttt aacactcaag tgatcttgtg gtctaaaaat ggtgagatat tgaataaagc
     8461 agctattggt gggcgtttca accaaatcaa agaattaaaa atggatacga aaaatctgaa
     8521 taccatccaa aatattgaat taaatgaaga cagtggctca tctgccctct ctttccgttc
     8581 gattacgaaa aaagcggaga cgaatcaaga tggcgttgcc tacatccaaa ttttagaaaa
     8641 tacaaatcaa atcaagaatt cattagcgac ttttcgcacg attatgattt tgtgtatgat
     8701 tgttttttgg attctctcta ttggtatcag ttattacttg tctagtctaa gcatgcgccc
     8761 tattattctt tcttggagaa gacaaaaaga atttgttgag aatgcttctc atgaattgcg
     8821 cacaccgtta acgattattc aaaatagttt ggaacatctt tttaccaagc ctaatcatac
     8881 tattattgaa gaatccgaaa gcatcgctca agcattgtca gagacgaggc gcctcactgg
     8941 attgacttcg gatttgctga caatcgctcg gaatgattct gatcagcagc tgctttcaaa
     9001 gcaaatgatc aatacacaag aatatatcga acaacttgtt aaaccatttc aagagatggc
     9061 catcatagat ggaaaagagt ttattctcca taacgatgca acattagaag taccaattga
     9121 tgaaaaaaaa atccatcaag ttttggttat tttgctggat aatgcattaa aatatacgaa
     9181 tccagaagat aagatcattt tggattcatc tgttaaccat aaagaatggc tgattcacgt
     9241 aaagaatact ggcccttcta tcagtgaaga agatcaagca aggatttttg atcgatttta
     9301 tcgggaagat caatctcggg cgaaagagac tggcggatac gggcttggct tggcaattgc
     9361 aaaacaggta atcgaacagc atcatggaca gatttctgta tccaattatc ttccacaagg
     9421 agtcgatttt aaagtccaat tgccgttgaa gcctaaaaaa taatgcttat ccctaaaaaa
     9481 gggctgtgac aaaaatcttg tcacagccct tttttgttgc gaataaacgg tgttccagaa
     9541 gtagcttctt cggaaataag ccgaaatttc tttaagctga ccacttctgt cacaacctct
     9601 ttagcttacg cttacgattt tttattgcgg tcttcaatgt gtacatcacc gcttgtgtca
     9661 atatccaatt cttctcggct aacatcttct gtcacttttt caacatcttc atgttcttct
     9721 ttatgaatcc caacttcttc acgaataact gtatgtttgc ttacatctac ttgctcttct
     9781 ttgattggga tagtaatcgt gtcatcttcc aatttttcgt ctgttccctg tgaagattga
     9841 tctgttactg gtttgcgttc gatgacgatt tcttcacgtt tgaccggtac ttctaccgtt
     9901 tcagtatcgt tgaccacatg tttgtggatg tcgacttctc cagttgtcac atcatgtgta
     9961 tttacatcta atttttcttc ttttagttga attgtatcat catctagatt tggtttgcga
    10021 tcgatgtctt cagtcttgct tgtacccatt gtatcagtct cgccaggtac gtccatcgga
    10081 tcagttcctg gtgtcatatt caatggatcc gttgtatttt gaaagcctgt cgtgccacct
    10141 acgtccattg gatctgttcc agtgccagtt tctaatccag tccccattgt gcttgctggg
    10201 ctaacagtat cttgtgtatc cattgtatct tctgttgttt ctggctgacg atagcctttt
    10261 actgtgatga caaattttcc atcagaaata tctcctctat attgatataa aggatcattt
    10321 tctggtgtag ccgtctcaga atcataggta tcaaaagaaa aagtatcttt tattttttcc
    10381 cataaagaac ggtcttcttc accatccatc cgattttcat ctgtttcaac atctatacca
    10441 gacaatccgt caaatcctag tctagatgct gcttcatcag tagtataaat aacgatatca
    10501 tctcgttcat acccttcgtt acgcaaccgt tcaattactg ataatgcttc ttccctcgta
    10561 ctatagcttc cgatgaccgt taaatttttc tcttccatgt aaattcctcc tagcaaatag
    10621 atttatgatt ggtatattgt tacttataaa tttattctat aggagacgat tgttttctac
    10681 aaatatttag attggaattt gattaaaaca atttaattga aatttgaaaa catttatgtt
    10741 aatgaaagtc atattctaat aaaatgtcat ttgtttctat atgaattttt atgaaaaatt
    10801 tcatataatt tccactcgtt gtgatggttt aatttatcca atccatcaat aagcaaacaa
    10861 cttatataaa aaaggattaa ttctcaatat aattgctcct accatagaat aaatcttcat
    10921 gtaaagtaat gaagtaccaa ctatttctaa tacttcttta agaattatcc caacaatatc
    10981 gttagacaaa ccattattga ataaatggag agccaatcga ttctgaaaaa atgttttcta
    11041 atttttcgga aataaaagaa agagcctcct gccattagaa cgaaccaaat ccatttcatt
    11101 gctcatgaag taaccacata gctaaaaaga ggataaatca attaaaagat caaaagaatg
    11161 actgcactaa taaaataact aaaaatgtat cttcttactt catatctttt agctagtact
    11221 tagttaaaaa tttgcttcct aagatcaaga caaactgtct atcttcattt gatgaaatgc
    11281 ggtaaaatat agaaaatgaa cactattgga gggaatttgt aatggacagc aaaactagaa
    11341 aacaactgca agaaaagtta aagcaacgta cacacttgct cccttccgtc tttcaacagt
    11401 ttttagaaga aaatcgttct tccctttcat taggcagtcg ctatgaatac gcaaaagatt
    11461 ttcatctgtt tactgattat ttgagaaaag tattttctga agaagtggat gatcagctga
    11521 ttatccattt agaaaaacaa gattatcaga atttcttagc taaaatctat cgacatactc
    11581 gttcgttcca aactacagcg aaccaagaaa cggagcaatt gtttgaaaat agctattacg
    11641 ggatttcaag gaagcaatat tcattaaatc attttttacg atttttgtat caaaaaggac
    11701 tgattgaaga agagatttct cttttgggta caagtttacc ggaaacaacc aaagcagctc
    11761 cgcgatatat cgatgcagaa cttttcaaag attttgagca tttgtttatc ccgattgaag
    11821 gctttcaaac aagcagagaa gctagctttg aagaaaagaa tagaccgagg aaccttgcaa
    11881 ttactgccat tcttctgtat tgcggattaa agatccatga agtagtagaa cttaaacgta
    11941 aagatgtatc tttgaccaag cagattctta atctgaatag aaaagaaaac agactgaata
    12001 aagtaccaat accaaaagaa gcgatgccat ttctggagaa ctattttaag ttaacagcac
    12061 aaaatacgga cgaaaattct tttgtttttc gttcctcaca tgatcagcaa atttctcctc
    12121 ggactattcg ccaaattttg agcaaaatta cagtatataa aaacgtatcg ccagaactat
    12181 gcagaaaaac atatcgttat tatgcagaac tatatttaga tgatgctgac gcggtaaatt
    12241 atttatgtgg taatcgatac ctctcatccc attcttttca agatatctgg gaaaagatgg
    12301 ttgatttttc ttatcacgaa ttagcggcat tcgttcgggt ttcttccata taaaacaaat
    12361 gtatgatctt tttttcacaa taaactatgt tattatataa aggattatgt tacgattatc
    12421 ttgaatttgt atattactta acaaaagata atggagtgtg aatgatggag accataacgt
    12481 attccccttt gaacttattt acgaattttc aagaagctgc agctaacttt tccgagaccc
    12541 cgattatctt tgatgagcca ctttcagctt tcccagaatt aggacttgaa acaacttaca
    12601 aaaaatgctg cgaaagtgtg ttgaaacggg cttatcaatt ggctcatctt ggagtgaaat
    12661 ccggagacaa agttattatt tataagagtt ccgcttttga cacatacctt ctagctgttt
    12721 ctgtgtctta ccttggtgca gtgcctgtca tgacttctta tcatctacca acaacaacaa
    12781 tggaagtatt tatcgatcgt ttagaagacc ctttcatttt atttgatgat gagacaaaaa
    12841 agcgagtgag agaaatttca aatggaacaa aatcaaaaca gattc
//
LOCUS       DACBYO010000083        12879 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.083, whole genome shotgun sequence.
ACCESSION   DACBYO010000083 DACBYO010000000
VERSION     DACBYO010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.083"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            8..730
                     /locus_tag="IVD26_002277"
     CDS             8..730
                     /locus_tag="IVD26_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAP6080209.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
     gene            788..2827
                     /locus_tag="IVD26_002278"
     CDS             788..2827
                     /locus_tag="IVD26_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAP6080210.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2936..4087)
                     /locus_tag="IVD26_002279"
     CDS             complement(2936..4087)
                     /locus_tag="IVD26_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP6080211.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLEYFTKKVYEV"
     gene            complement(4241..4771)
                     /locus_tag="IVD26_002280"
     CDS             complement(4241..4771)
                     /locus_tag="IVD26_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080212.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4870..5220)
                     /locus_tag="IVD26_002281"
     CDS             complement(4870..5220)
                     /locus_tag="IVD26_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAP6080213.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5377..6906)
                     /gene="ahpF"
                     /locus_tag="IVD26_002282"
     CDS             complement(5377..6906)
                     /gene="ahpF"
                     /locus_tag="IVD26_002282"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAP6080214.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6916..7479)
                     /gene="ahpC"
                     /locus_tag="IVD26_002283"
     CDS             complement(6916..7479)
                     /gene="ahpC"
                     /locus_tag="IVD26_002283"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAP6080215.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7623..8285)
                     /locus_tag="IVD26_002284"
     CDS             complement(7623..8285)
                     /locus_tag="IVD26_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6080216.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8469..10115
                     /locus_tag="IVD26_002285"
     CDS             8469..10115
                     /locus_tag="IVD26_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAP6080217.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10106..11188
                     /gene="uxuA"
                     /locus_tag="IVD26_002286"
     CDS             10106..11188
                     /gene="uxuA"
                     /locus_tag="IVD26_002286"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP6080218.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11296..12849)
                     /locus_tag="IVD26_002287"
     CDS             complement(11296..12849)
                     /locus_tag="IVD26_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6080219.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
BASE COUNT         4309 a         2365 c         2386 g         3819 t
ORIGIN      
        1 atctattttg ttactgctta cattagtagt tggctatttt tcgattgagt ttatccatgg
       61 attttcgtct gcaaaacaga gttcaactgt gaaaaaggta gagccgaaaa gtatccctac
      121 cacactaaat gtggctttga ttggttcaga tgctcgttcg aaagacgaaa acggtcgctc
      181 ggattcactt ctggttgcac aatacaacca gaaaacacaa caagcaaaac tgatctctat
      241 catgagagat tcatatgtcg atattccagg ttacggaatg aataagataa atgcagctta
      301 ctcttatggg ggagttgatt tattaaatca aacattaaag gaaaatttca aatttgaagc
      361 tccctattat gcaagtatca catttcaaga ttttatcgat tgcgttaatg aactgtttcc
      421 tggtggagtc aagatcgatg cagaaaaatc tctagattta gatggcgtat atataaacaa
      481 aggagagcaa gtgatggatg gtaatacttt actccagtat gctcgatttc gggaagacaa
      541 agaaggagac ttcgggagga tcagaaggca gcagcaagtg atcaaagcta tctctcagca
      601 gctgaaagac gtaacttcaa tattcaagct acccaaagcg gttgggaaat tacttggtag
      661 tatccaaacg aaccttccag aaagtgtgct tctggattgt ggtatggatt tcctcaaaga
      721 catatgttag aataaacagg tataaatagt gaaataaagg aatgacaagc aagagaagga
      781 ggaaaaaatg aaaagaagtg acaagcacgg caaaaatcga acaggcgctt atattgccgg
      841 cgcagtgatc ttaatagcag ctgcgggtgg cggttatttt tactaccagc actatcaaga
      901 aacccaagca gtagaagctg gagaaaagac agttgagcaa tttgtccaag ctttgaacaa
      961 gggagattat aacaaagctg cagaaatgac atcaaaaaag gcggcaaata aaagtgcatt
     1021 atctgaaaaa gagatcttag ataaatacca gaatatatac ggtgctgctg atgtcaaagg
     1081 acttcagata tcgaatctaa aagtagataa aaaagacgat tctacttaca gtttttcata
     1141 taaagcaaag atgaatacct cattaggtga attgaaagat ctttcttata aaggaacatt
     1201 agacagaaat gatggtcaaa ccacgatcaa ctggcaaccc aacttggttt ttccagaaat
     1261 ggaaggaaat gacaaagtaa gcctgaccac acaagaagca gcaagaggga atattataga
     1321 tcgaaatggt gaaccattag caacaacagg caaactaaaa caattaggag tcgttccaag
     1381 taaacttgga gatggaggcg aaaaaacagc caatatcaaa gcgattgctt cctccttcga
     1441 cttaacagaa gatgctatca atcaggcgat ttcacaaagc tgggtacaac ccgattactt
     1501 tgtcccattg aaaatcattg atggagcaac gccagaactt ccagctggag ctaccattca
     1561 agaagtagac ggcagatatt atcctttggg tgaagcagct gctcagctga ttggttacgt
     1621 gggagatatc acagcagaag atattgataa gaatccagaa ttaagcagta atggaaaaat
     1681 cggtcgctca ggtttggaga tggcttttga taaggatctt cgtgggacaa caggtgggaa
     1741 attaagcatt acagatgcag acggtgtaga gaaaaaagtt ctgatcgaac atgaagttca
     1801 aaatggcaaa gatatcaaat tgacaatcga tgcgaaggca caaaaaacag cttttgacag
     1861 tctaggagga aaagctggat caactgttgc gacaacgcca aaaaccggtg atcttcttgc
     1921 gcttgctagc tctccaagct atgatccaaa caaaatgaca aacgggatct cacaagaaga
     1981 ttacaaagct tatgaagaaa atcctgaaca tccattcatc agccgatttg cgacaggtta
     2041 tgctcctgga tctacgttta aaataattac agcagcaatc ggtctcgaca acggcactat
     2101 cgatccaaat gaagtgttga cgatcaacgg gcttaaatgg caaaaagaca gttcttgggg
     2161 atcttttcaa acaacgcgtg tcagtagtga tgtatcacaa gtagacttaa aaactgcttt
     2221 gatctattcc gataatatat atgcggcaca agaaacgttg aaaatgggtg agaaaaaatt
     2281 tcgtacaggc ttagataaat tcatttttgg tgaagacctt gatttgccaa ttagtatgaa
     2341 tccagcacaa atttctaatg aagatagctt taactcagat atcttgctag ctgatactgg
     2401 atatggacag ggcgaacttc taattaatcc tatccagcaa gcagcaatgt attctgtttt
     2461 taccaacaat ggcacacttg tctatcctaa attgattgca gataaagaga caaaagataa
     2521 gaagaatgtc atcagcgaaa cagcagtaca aacgatcgtg ccagatctga gagaagttgt
     2581 gcaagatgta aatggtacag cacattctct ttctgcttta gggattccgt tggcagcgaa
     2641 aactggtaca gcggaaatca aagaaaaaca ggatgtaaag gggcaagaga acagtttctt
     2701 gtttgctttc aatcttgata accaaggtta tatgatggtc agcatgttgg aaaataaaga
     2761 agatgatgat tcagcaacca aacgagcatc ggaactattg caatacctca accaaaatta
     2821 tcaataaaaa attgcttttt aagtacagta aaaggactgt ggcgttatcg tcacagtcct
     2881 tttttcaaat aaacggtttt cacgatgtct ctttcacaac ttctttttga tttactcaca
     2941 cttcataaac tttttttgta aaatattcga gaacaagtgg agaaataagt gtacttaata
     3001 aaatcacgat aactaaaggt gaatagtact gtggttcgat caattgactt tgctgtccaa
     3061 tttgtaaaat gatcaaagcc atttctccac gcgaaatcat accagcaccg accatcaatg
     3121 aactatgttg agaaaaaccg gcaatctgag caccaaaata acctccaagc aatttggtca
     3181 aaatcgctac aagcgtcaat atagaaataa agagtagttg ttcactaaag tcagaaaaat
     3241 caacttctaa tcctacactg acaaaaaata ctggtataaa tactgcatat cctaaagcct
     3301 ctacattgtg gtatacttct tctttaacct ttgtctgact gacagctatc ccagcaaaaa
     3361 aagcaccaat gacagagcta agcccaacaa gatccgctac gtaagacatt cctaaacaaa
     3421 taactagcga tacgatgata atagaagaat ttgcgtacac tttttctgca aatgaaagta
     3481 ggaaaggcgc aatccatttg actaataaga aaataaaaac aaaataaatt agctgttcaa
     3541 tcaaaacaag cggtaaagaa gcattgctag aagcttcccc cgttagaaaa gataggctga
     3601 aacttagaac taaaacgact aaaatgtcat ctaccacaga agcacccaaa attgttgatc
     3661 cttcttttgt attcactacg tttagttctt ttaatacttc tactgaaata ctgacagaag
     3721 ttgccgcaag aataatccca aagaaaatcg cttcatttcc cgaaacttgg aatgctttgc
     3781 ctgtcaacca gccaaaaaca accgggaaga tgatcccaag caaagcaacg aacataccag
     3841 gtcggaaata ttttttcaaa agagataaat cactttccag accagctaaa aacattaata
     3901 agatcacacc aatctccgaa aagtcatgga ctagaatatc aggtttgacc caattcaatc
     3961 cagcttggcc tagcaaaaca ccaacaagta attgtccaat cactgctggg atacctaatc
     4021 tccgcgagat atgtgagcca atcgttgttg aaatcaatat caggcataaa ataccaataa
     4081 attccattct catcattcct ttgtataaaa tatagcccga acttagcata acatacatta
     4141 ttgaaaaaat aggaaaatat actcacaaaa aaaccaacaa tccaaaagat ttttttggat
     4201 tgttggtttt tatacggtct attttaataa ctaaaaatga ttaacgtata gtcatttttc
     4261 ttattctgat gaaattgata atctcctgga tgcccatgaa aatcaaaata aagccgaata
     4321 tttggaatag aagcatcaaa cttttgaatg gattgaacaa taagacgaat ccgccaatca
     4381 acaacagaat actactataa acactccaac ttttagcttt tgtattcatg ctgaagaaca
     4441 actggaacaa gctgttgatg ataacagcta atccaagaag aatcggcagg atagaaacga
     4501 ttgcaggtgc aaaagcatag acgatcagag ctaagatcag gaaaaaaaga ccactgaaca
     4561 gaccgatact ccaagaacct gttttccttt taaaacggta agcctcaaaa agattcaaca
     4621 acccaagcaa aacaagatag gcggtgatca gataaccgat aaaatgaaaa acagcagaag
     4681 ggtttagcac aatcgcaatc ccagaaataa tataaacagc agctcttaat aaggcgtatt
     4741 tttgaatatt ttgtttaatc gtctcaaaca tataagaaaa cctcctttga cttattttaa
     4801 cgtgaactag tcattttacc aaattaaatg ttacaaaatg agcgaaggag aagaatatct
     4861 ctggaaaaat caacttctga ggatcttttc catttttttg ccttttgcta gctcatcgat
     4921 cattttatct aaataacgaa tttctttcat caagttatcc tcgatgtctt ctactcgtac
     4981 accacaaaca acacctgtaa tcaaggaacg tgaaggattg gggacagggg cttccgcaaa
     5041 aaattgttcg aaagtcactt gtttttgtag ttgatattct agttctgttt gggaataacc
     5101 cgtcagccaa caaatgattt catctacttc ctcttttata cgatcttttc tctccgcttt
     5161 tgctacatac ataggataaa cgcttgcaaa acttgtcgta aaaatacgat tttgcgccat
     5221 aatcagtcac ctttcttttt ttcaaattat ttactactta tagtatataa gaaaaagaga
     5281 agaaaaagcg attattcaaa aaaacaaaaa ggattgtgac aaaattcttg tcaccatcct
     5341 tttttccgct ctctgacttt ttacaatctt catagctcaa gtgcgcatca gataatcgaa
     5401 tgctcctaaa gctgcagtag ctcctgaacc cattgaaaca atgatttgtt tgtatggact
     5461 atctgtacaa tcaccagctg cgaaaacgcc ggggatattc gttgcgccat ttttctcggt
     5521 cactatttca tttcttggat tcatttcgat cgttccatct agccaatccg tattagggag
     5581 taagccgact agaatgaata ctcctgaaac agctagtgta tgcatctcca tcgtacggcg
     5641 atcgatatag gagagagatt ctacctgatt cgtaccgctg atttctttcg tcgctgcatg
     5701 tttgataaca gtgacattcg caagagagac tagtttatcc tgtaagattt gatctgcttt
     5761 taattctggt aagaattcta gaacatatac atgttttgct aacccagcca aatcgattgc
     5821 tgcttcaaca ccagaattac caccaccgat aacagcaatc tcttttcctt taaataaagg
     5881 gccgtcacag tgtgggcaat aagcaattcc tttattttta aactcttttt cgcctggtac
     5941 attgatagaa cgccagtgcg cacctgtcgc gatgatggcg gtttttgctt taagtgatat
     6001 accgttagct aagccaatat taataaaatg ttgctcttta tttaaggaaa cggcctgttg
     6061 attcatcata atgtcgatag ggtaactacg cacatgactt tctacttgct gcatcaattt
     6121 tggaccttct gtgtaagagg taccaatcat attttcaatc cctagtgttt caacgacttg
     6181 tccgccgaaa gaatcagcga caagtcctgt acggattcct ttacgtgctg catagatagc
     6241 tgcactacta gctgctggtc caccgccaat tactaataca tcataaggtt ctttttcaaa
     6301 caactcttct tcaatcaaag ggccagtgat tttttcaaca atttgttcga tcgtcatgcg
     6361 tccgctacta aattcttctc catttaaaaa cacagttggc actgccatga tttttttatc
     6421 atcgatttct ttttggaaca tcccaccttc aatcatcgta tgagtaatat ttggatttaa
     6481 tacagctaat atattcaatg cctgtacaac gtcggggcaa ttatgacaag tcaagctaac
     6541 ataactgtca aaatgcaatg tttgtgttat ttttttgatt ttaagactca aagattcact
     6601 gattttcggt gcccgtccac taatttgtaa catagccagt aaaaaagagg aaaattcatg
     6661 accgaggggg ataccagcaa aaacgattcc actttctttg ccaactggat tgatagaaaa
     6721 actaggtgtg cgcatcgaat ctcttttttc ccaagagatt ttaggagaca tttctgctat
     6781 ttccttcgta aattcagcta gtttttgact attttcacta ttatccaaac taacagaaaa
     6841 aacaatagga gattcaatca gtgctaaata ttgttcgaga ttttgtttag tttctttgtc
     6901 taacatatcc accacctaaa tctttccaac aagatcaaaa cttggtttca atgtttcgcc
     6961 actttctttc cattttgccg gacaaacttc acctgggtgg gtacgtacat attgagcagc
     7021 gcgaatctta tcaatcagtg cactagcgtc acgaccgatt ccatctgcat tgatttccat
     7081 agcttgaacg attccgtctg gatcaataat aaatgttcct cgctgagcta atccttgctc
     7141 ttcatccaaa acatcaaaaa tacgagaaat ctgatgagac ggatcaccga tcatcacgta
     7201 ttcgatttta ccgatagcat ctgatgtatc atgccatgct ttgtgagtaa agtgggtatc
     7261 ggtagagcaa gaaaagactt caacacctaa agatttcaat gtactgtatt gttcttgtaa
     7321 gtcttctaat tcagtaggac aaacaaaagt aaaatcagct ggatagaagc aaagaatact
     7381 ccagttcccc ataagatctt tttcactgac ttctaaaaat tctccttgat gataagcatg
     7441 tgcattaaat tcttcgattt ttttcccaat caatgacata gtaaaacctc caataataat
     7501 tatttattta taattattgt aatttagttg gagttgcaaa gtcaatggat attttgttat
     7561 ttaataaaga ttactcaaaa acgaaggtta attataaaaa tagaagaggt cgcaagaaaa
     7621 tgctactgct ggaaatactc gggataacgt tgagtaacag tttcctgttc tttcagcatc
     7681 atgtgtaagt gcaatcccgt ttgaaatcga gcttcttctg gttttttatc aactaaagcc
     7741 ttgagtaaat cataatgttg ttccatgatc gtttcccatg gaagcccctg aatggtcact
     7801 cgtaaccagc ggaaacgttc taaatgggta ttatggtcat ctaaccagtt ccaaacttct
     7861 tttcttcctg caatttcgaa acaagcttca tgaaataaat tatctgcacg gaaaaaagcg
     7921 cgttcgtcat ttattttgac tgctttttct tgttcttcta aaatcgtttc tagcactatt
     7981 cgtgtttgtg tgtccaattt ggaacaacat tcaatcatga tttgctcttc caactgttct
     8041 cggacaaagc gagcattttc tgcagaaaca agattaattt tggaaacata cgtaccactt
     8101 tgaggtatcg tatacacgag ttcttgctga cgtagttgaa tcaatgcttc gcgaatggga
     8161 gtccggccga tagcaagatg ttcctccagt gccttttcag atattttcct tccaggttct
     8221 aagtcagcat agataatttg tttacgaatc gcttgataag cttgtgattg caagctgctt
     8281 ttcatcttta ttcctccaaa atcatttcta tgaacgtagt ataacagaag aggtctgaaa
     8341 aacaatctgg tatgtcacat taactagtaa atttgtataa atagtaaaat tttggttgac
     8401 atagcgattt ttattgtata aaattcactt gaatacaaaa actaatatgt tagtttagga
     8461 ggggaaaaat gattgattta aacaactgga ggaactttat ccctgaatta tctcaaaaag
     8521 aagtagaaat acctcatttt gaccgtgcat cattaagaga aaatggacaa aaaaatcctg
     8581 tctggatcca tttcggtggc ggaaatcttt atcgaggatt tcatgcagaa atcgctcaac
     8641 gtttagcgga tctaggcgaa ttgtccactg gtgtcattgt ttgtgaaaca ttcgatgaag
     8701 aaataattga aagggcttac caagattttg atgatttgat tcttgaagtg gtcatgccaa
     8761 gcagtggaga gttcgtcaaa cgtatattag ctgcgacagc tgacagtctg tattgtcatc
     8821 cagattgttc tgaacacttt gataagatga ttcgacactt tgaaaatcct agtttacaat
     8881 tagttacttt tgctattact gaaaaaggtt atcgattgaa agatacaaat aataaatata
     8941 taggaccgat tgcagtcgat ataaaaaatg gtccaaagaa gccatcacat acaatgagta
     9001 ttcttgctgc gctactttat aaacgttttt tatctggagc ttggccgatt gcacttgtct
     9061 ctacagataa tttttcacaa aacggtagtc aattacgtac ttctttgcta acgatcgcaa
     9121 aagaatggca aaaggaaggt tatgtacaaa atacatttat ccaatactta tcgaatgaag
     9181 aaattgttgc gtttccatgg acgatgattg atcgtatcac cccgaatcct tccttgtcag
     9241 ttagcaaaat gttggcaaaa gagggctttt caaatatgtc gattttccaa accgcaaaag
     9301 gaaataatat tgctccattt gtcaatacag aggacatcca ttatttaatc atggaagatc
     9361 attttcccaa tggacgtccg aaattcgaaa aagctggggt attcttgact gatcgtgcaa
     9421 cggtagataa agcagatacg atgaaggtga cgacttgcct taatcctttg catacgtctt
     9481 tagctattat gggttgttta ctggggtata ggagcatagc tgaggagatg aaagatccag
     9541 atttatcgct gctagtttct gaaatcgggt acaatgaagg cctcccagtt gtggagtctc
     9601 caggtatcat tgatccaaag atctttctgg aagaagtaat tactgtgcgc ttttctaatc
     9661 caaatattcc tgatatgcct cagcgaatcg ccacggatac ctctcaaaag gtggcgattc
     9721 gttatggtga gacgattaaa aaatatatgg aaatagaagt taaagacccg cagacacttg
     9781 tattcatacc attgactctc gctgcttggc ttcgatacct tattggcatt gatgatcaag
     9841 gaaaaccatt catcccgagt ccagacccac tattgacaga ctttcagcat aagctttccg
     9901 atattcaact gggtacgcaa gatacatcac atattcatga gaaaatggct cctattttgt
     9961 caaataaaga aatttttggt gtagatcttt accaagcaga gcttggcaga aaaatagaag
    10021 aaatgttcat caagatggta gcaggaccga atgccgtacg aaaaacatta caggattact
    10081 tacaagaaca tggaggaaat ttatcatgga aatgactttt agatggtacg gatcacagga
    10141 agaaaagatt accttagatg aaatcagaca gattcctgcg gtcaaaggga ttgtaggcac
    10201 attgatggat ataccagtag gagaggtatg gcccagggag aggatcaaag aactaaaaga
    10261 agaaattgag tctcgtgggt taacactaaa agtaattgaa agcgtcaatg tgcatgatgc
    10321 cattaaaatt ggattacctt cccgtgagca gtatatcgaa aactataagc agacaatccg
    10381 aaacttggca gaatatggaa tagaagtcat ctgctataat tttatgcctg tatttgactg
    10441 ggtgaaatct gaccttgact accgcttaga agacggctca tccacgttag cttttatatc
    10501 tgatgatatt ccagatgatc caagagaaat cgtcgcgcgc atcgaacatt ccagcaatga
    10561 atttgaattg ccgggatggg aacctgagcg cttagctcat atcaaatcct tgcttgaagc
    10621 ctatgcatca gtagacgaag aaaaacttcg agaaaatttt gcctattttc tccaatcaat
    10681 catcccaaca tgtgaagagg taggggtcaa aatggctgta catccagatg atccgccata
    10741 ctcgattttt ggattacctc gaatcgtaaa gaatcgagaa gatttagatt ggttgtgccg
    10801 catagtagac agcccttata acggaatcac tctttgtaca gggagtattg cagaagatcc
    10861 agaaaatgat gtatatggga ttttagcaga attttgtcaa agagatcgaa tcccatttgc
    10921 acatgttcga aatattaaat ttttagctaa tcgagatttc tatgaggcac cgcataaatc
    10981 cgaatacggt tcattagaca tgtaccgcat actaaaaaca atgtatgaca acggatttaa
    11041 cgaatacatc cgtcctgatc atggaagaat gatctggaat gagacaggaa gaccaggata
    11101 cggcttatat gatcgagcat taggtgctgt ttatctaaat ggattatggg aagcaatcga
    11161 aaaaggaaac aaaagtaaag ataattagtg aaaaaaactg taattttatt atgtaaataa
    11221 gaaggatgtt caaattcttg atacataaat ccggaggttg ttaataagca ttcggattta
    11281 tgtatcttat ttggtctagg aagtaacttg attttctttt ttcgattgat ccatgagtgc
    11341 ttcttctttt aattcaaaga tatattctga gatcctcata atcacttttt tccagtcttc
    11401 tggtgtgatg attcctttta aaatatagat ttttttgata tgagaaggca attgtttcaa
    11461 agggcagtcg ctgataacga tgttgcagtt ctccataaaa tcattttgta ttttgatcga
    11521 ttcatttgaa aaaatttgtt ctatcttaac gatcagatct ttactgatat aaaaatcacg
    11581 cgtatagttc acaccaatca caattcgcgg ctgttttttg tagcgatcat acaaatgtac
    11641 taggtcttca accatccatt gcacattttc cttttctaaa ataactggta acaagtgttg
    11701 attttgttct ctgaaatcca tataaaattg ttcaatggcg gtttggactt ctttcaacac
    11761 gctatgttct tgataaagca tgaaagtagg aaggggcgta tttggttgat tgaagttaag
    11821 aaatccatta taaagtttat ttcgtgcgaa tgccaatgag taaagaatct tttctttttc
    11881 aggtataaac aaatcaaata cagtacaaaa ggactccacc atttctcttg aataaagaac
    11941 atgaggaacg tttgcttttt ttaaaagttt gtattgctcc aagcttgttt cttccgattc
    12001 gattttcgtg atagaaagtc gagctaaaat attcactaag atgcgttgtt cgcgacaaat
    12061 tggcagatta ggtcgcaaaa tatctacaga gggatcaata aaaaagtcaa tatattcata
    12121 ctctgtgaat tctttttgta cgtctttcac agaagttgca ggaaaattct ctttacatat
    12181 ttttaataga aaatataatt tatctatcat accgctattt agtcggtcaa gtacttcttt
    12241 tttaaaaaaa gtattcatca taaaagccac tacttgcgga tcttcatcat aaaattctgt
    12301 agcagtactt gaaaagatgt tccaataaat atctaatgct gcatattgaa tttgtacctc
    12361 ttttccagaa aaagactttc tgccattatt agaaaaggag atagacaaac cgtacaatgc
    12421 taaaaatgca ttaatctttt tcattttcgt atacaaataa gaggcactat agtttgtttg
    12481 ctgacttaaa ctgataatcg aatttgtctg acagctgaac aaagaagtca agatctgata
    12541 actgactgat tcgttgcagt atcttccaaa tagacgataa tagcagtaag ccggatcaat
    12601 tccttcaaaa ttcaacttta aaaaaggttt ttgcttatca atatgcagtt ctgttagatt
    12661 gagacgctca aagtcttgtt ctaattcttt gatgtatagt aaaaaatttg attcagacat
    12721 atggaaatga tctgctaaat attgtgtagt aataaagaaa cgatgttcag ataggaaaag
    12781 aaaaatatct aattttgtat tgcttttttt cttcaagaga aacgttttaa tcgcttcttg
    12841 agtttgcatg aaagaggctc ctttttactt aaattgtta
//
LOCUS       DACBYO010000084        12737 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.084, whole genome shotgun sequence.
ACCESSION   DACBYO010000084 DACBYO010000000
VERSION     DACBYO010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12737
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.084"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            96..539
                     /locus_tag="IVD26_002288"
     CDS             96..539
                     /locus_tag="IVD26_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6080220.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(545..1729)
                     /locus_tag="IVD26_002289"
     CDS             complement(545..1729)
                     /locus_tag="IVD26_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAP6080221.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            1997..2695
                     /locus_tag="IVD26_002290"
     CDS             1997..2695
                     /locus_tag="IVD26_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAP6080222.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2702..3379
                     /gene="nth"
                     /locus_tag="IVD26_002291"
     CDS             2702..3379
                     /gene="nth"
                     /locus_tag="IVD26_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAP6080223.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3505..4038)
                     /locus_tag="IVD26_002292"
     CDS             complement(3505..4038)
                     /locus_tag="IVD26_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080224.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4335..6716)
                     /locus_tag="IVD26_002293"
     CDS             complement(4335..6716)
                     /locus_tag="IVD26_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAP6080225.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6706..7353)
                     /gene="recU"
                     /locus_tag="IVD26_002294"
     CDS             complement(6706..7353)
                     /gene="recU"
                     /locus_tag="IVD26_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAP6080226.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7417..7956
                     /locus_tag="IVD26_002295"
     CDS             7417..7956
                     /locus_tag="IVD26_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAP6080227.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8046..8465
                     /gene="gpsB"
                     /locus_tag="IVD26_002296"
     CDS             8046..8465
                     /gene="gpsB"
                     /locus_tag="IVD26_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAP6080228.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8487..8854
                     /gene="rnpB"
                     /locus_tag="IVD26_002297"
     ncRNA           8487..8854
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="IVD26_002297"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9063..10229
                     /locus_tag="IVD26_002298"
     CDS             9063..10229
                     /locus_tag="IVD26_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAP6080229.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10275..11771
                     /locus_tag="IVD26_002299"
     CDS             10275..11771
                     /locus_tag="IVD26_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAP6080230.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11852..12535
                     /locus_tag="IVD26_002300"
     CDS             11852..12535
                     /locus_tag="IVD26_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP6080231.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2230 c         2630 g         3604 t
ORIGIN      
        1 cttggtttca gattgggttt tcctacaaaa tatttttatc tttgttgaat aggaaacaaa
       61 aaaacaatat aatgaaagaa aaagaaggtg tagaaatgga taaaagacaa ctgctaatag
      121 aagaatatct ggatttagct aatgagatta ttcatcgtaa taaaccagaa atggaaaaag
      181 aatttgcagg atttactcta aatgaactag aagtgattga acatatcggg aaaatccctg
      241 atcctaacgt gacaaaatta gcgaatgcta gttacatgac tagaggagcc atcagtaagc
      301 taacaaaaaa actgatagct agagggatca taaacactta tcaaagcgaa gagaataaaa
      361 aagaaatcta ttttcaattg acgccaatcg gacaaaaaat aaggaataga cacgagcaac
      421 tccatcaaaa atgggtacag cgagatgcta ctgtatttga aaatatgtca aaagaagaat
      481 ttgacacagt atttcgtttt atcggtcgat acagagaatt tatacgaagt agcaaatgaa
      541 gctactattt tttattgtag tgataatagg caaaaatcat aagcaaaaat ccgaataccg
      601 tcggaagaaa tggtgctgca gcataaagct gtcctgcgat tagcgggccg atgacgcgcg
      661 atagagattg tatactttgg gtaccgccca ttacaagacc ttgctggtta tctgagacag
      721 aattggatag ttggccattg aatacaggag taaaaataga atcaccgaaa ccataacaga
      781 taatcccaaa taaaaacaaa atcggcagta gaagaattcc agataatgtg atgaatagat
      841 aggcgaggat ttcactgaac atccctattc ttgtgatctg ctgttctgaa aattttttga
      901 gcaatcgagg cataatgaac aattgcgaga cagtatccaa gattccaatc aaagagaagc
      961 ttaaaccaac caacccagcc ttccactgaa aggcgtcaat cgaaaattga gaaaagatag
     1021 attgaagaga gccagctgcc aaccaaacag caaaacctgc tgtcaataaa ggaataacgg
     1081 atgaaatctt gaataattgt tgtaattggt gaaaaggtct tacatgggag aaacttaaat
     1141 ctactgaacg tttttttatt ggaaggcttt ctagcataaa tgtgtagcca taaacggcat
     1201 ttaagaaagt aaagagtgct ccaataaata taggaacaga attccccaac tcagctaata
     1261 gaccccctat aataggaccc agcgttgttc ctataccgac taaagcaccc atccatccaa
     1321 aaactttggt tctttcatta ggttccgtga tgtcggcaaa gtaagcatat aaggtggaga
     1381 tttctcctgc cgtcaatcct tcaatgatac gaccaaggaa caacatccat atcgaatttc
     1441 ctaaaccaaa aagcaaatat ccgatacttg atcctaataa actgataata aggatcggat
     1501 gacgcccaaa atgatcactt aagctaccga gaatgggggc agataagaag gcagctagag
     1561 cataaacaga catgagcaaa gtgatataga aagcttgctg atgtatggag tgagaataag
     1621 gcagcgttaa aaacggaagt acaggactga cgatagtaaa tcctaatcca gtgaataaga
     1681 cagagacgta tccaaaaact ttagaatgtt tatttgtgaa actgtacatg taaaaactcc
     1741 tttatgcaat aatgttaact tggaaacaaa aatagtgtat agtaattttg tttccttgtc
     1801 aacattctaa ggaacagcga aatctactta atttatttat tccgaaaagt gaagatacgc
     1861 atcaaaaaca tgaacaaaca aaaatcaagt agacgacatt gtaaatctga ccgatcagtg
     1921 aagtaaatag aaaagaaacc tgttcttgct tcccatgttt tttttacgta tactgtgatt
     1981 gagcggagga gaaatcatgt tgaatttaga aaattactta agcgctggac aaacagtcat
     2041 atctaatctt ttacttaaaa attatcatag gatcggtcta caatctgaag aatttttatt
     2101 tgttctacag ttgcatatgg cacagcttga aggagatact ttccctgatt tgcagatgat
     2161 tgctatggat atgggaatca aacaagatca gatttttcaa atactggatc gtctcgtaac
     2221 aaatggattt atcaagatag aaacgacgat tgtcaacggt aaaaaagcag atcgatataa
     2281 tctttacccc atctatgatc tattaggtga gtatttaaaa acacaagaaa aaaaatacga
     2341 agaaaaaaca caagaaaaag aaatccagtc agtgtatcaa ttatttgaac aagaatttgg
     2401 acgcccgctt tcttcgatcg agttccagcg gatcggacaa tggctagaag aagaccatta
     2461 tcagccggaa attttgaagc tagcactgcg ggaagccgta ttaaatcagg cttatagttt
     2521 taattacgtt gaccgcattt tgctatcgtg ggaaagaaaa aatctacgta caaaacaaca
     2581 agtggaagaa gaccaaaaac gaagaaaaca gcagcttctt caaagagaag tagaacagtc
     2641 agctcaacaa gaagaattgc cgaaagtctc actgaaaaat tggttggagg agtagcggaa
     2701 tatgttaagc aaacaaaaaa caatggaagc tctagaaacg atgtatggaa tgtttcccga
     2761 agcacatgga gaactcaagc acaataatcc atttgagtta ttgattgcag tgatcttaag
     2821 tgcccaggcg acagatgtat cagtgaataa agcaacgcca gatttgtttg cctcttttcc
     2881 gacacccgat gcgttagcag aagcttcaat cgatgaaatc attcttaaaa taaaaacgat
     2941 tggtttgtat cgaaataaag caaaaaacat caaagcgtgt gcacagcagc tgattgaacg
     3001 tttcgatggg caagtgccaa cgtcaagaga agaattgatg tctcttcctg gtgtaggcag
     3061 aaagacagca aatgtcgtat tgggggatgc attcgggata ccagcaatcg cagtagatac
     3121 ccacgtggaa cgtgtctcaa aacgcctgag gatctgcaaa ctagatgcta cggtcatgga
     3181 agtagaagaa acactgatgc ggaaagtacc acaagaatta tgggtaaaga cacatcatac
     3241 actgattttt tttggtagat atcattgcac ggcaagaaat cccaagtgcg aggtatgtcc
     3301 tttgctatca atatgtcaag atgggaaaaa tcggatgcgt ctaaaagaaa aggcgctaaa
     3361 aaagaaacca cgcctgtaga cgtggtttct ttaattgcaa ataaatgtat gaattatctt
     3421 gttattatgg agaaaagctg tttcgtttat cttttttgca tgaaaaagta aatgtacata
     3481 ctcagtagct aggatggtaa cttattacaa tttattgcga taaaaataaa agttgttatt
     3541 tttattggga aaatacccga tgtagaaaat aatgccttcc aatataccta taaaataagt
     3601 ccagtattcc aaaggattat ataaataagt gacgtatcta tctaaaggtg taataaaaat
     3661 gataagtgat aataaaaaaa taccatttat aactaaacat aaactaatgg atttgggcgg
     3721 tttcaggctc atcagaaaaa tatagattct ggtgaacaac aaccataaaa aagtgagaat
     3781 cattgcatga gagcttcttt ccataaattt tcctttaaga gtagtgctta aaagtacaga
     3841 aaaaataata aatgcaagga taggagcaat taaagtaaat ttatttaata ataaacaaaa
     3901 tttttcagct tttttattct tggaataacg aggtattgtt ttcgataaaa aaagatggtg
     3961 cagacaaatt atgataatta agcatactat cagataactc aaaatgaagc cttctttcaa
     4021 aaaattattc aaaaccatat attgtatttt ttatttgata ataacaatgg gattattaag
     4081 aagtggcact aaataaaaga ctagtgtgta tttagccgat ttaattataa acaagtaaat
     4141 ggataaagta tatgtaatga taaaagaaaa atggattttc taatttttaa gctaaatgtt
     4201 agatcacaca tgtatatgct ggatagtctt ataaaaaatc atgtaataca gcttggtaca
     4261 tgatttttat ttgtagctgt tttttacata gacacaaaaa agaaaccacg cttgtagacg
     4321 tggtttcttt tttactatct gtttccagaa gctgaggtgc tgctggatgg tgtatggtca
     4381 tttgcagcat ccgctccgct agttgctggc tcactggaag aagcaggagg agcagatgaa
     4441 gacggtgtcg agctttcttc ggatgaagaa gaaggaaccg ttgttgaaga cgctggctcg
     4501 cttgtttctg ctgtcgtgct ttcttttgag gactcagcag ttgattcgct ttgactagta
     4561 gagctagagc tttgagtcgt tgtctctgtt gttgagcttc caggagtctg gacatagctg
     4621 gaagatggaa tagttgttga tggtgtaatt gcattcgatc tagctgtata ttgatctttg
     4681 tagtacagtt caccgcccac acgaattaat ccgcttggca tctcccagtc tgtatttgtc
     4741 acgttagctg aaacatactg cataagctcg cgataaacat cagaggctac gtgtgacgat
     4801 tctgaagtga caggcgtcat ttttttattg taacctgtcc acacggaaat cgaataattt
     4861 ggcgtatagc ccgcaaatag gatatctgga tacaccccag aagaaatacc aagttttgca
     4921 tactcgtcat ctgtgtaatt ggatgttccg gtcttaccgg cttgatataa cccagcgatt
     4981 tgcgcattcg taccagttcc ttcagtgatc gtatctttta aaatgtctgt gatcatataa
     5041 gctgtttctg gagacatggc tgtttttcca tctggctcat aagtttcttc tgttccgtct
     5101 tggaagacga ttttattaac atattgaggt ttgtaataag tccctccatt ggcgaaagcc
     5161 gcataggctg ctgccatttt taaggaagaa gctccgtatt ttgtcccatc ttgttcttcc
     5221 gtattactag agatcgcatt cgattgatgg atcgtactgt attcgatccc aagatttttt
     5281 aagaaagaag ccactttatc tgaaccgact tcattgaata atttgactgc tggaacatta
     5341 cgggataagt aaagtgcttg gcgtaaagta atggtgccca tatattgatt atcccagttt
     5401 cctacaggag tcgaagtccc ttcatagtta tacggtgcgt cagtaatagt ttttccagta
     5461 gaatatttca aatattcaaa agctggtccg taatctgtga caggtttcat cgtagaacca
     5521 aaatcacggg aagtattcac tgctaagttg ttgcctaaag ttacgtcttc tgcgatgtga
     5581 cgtccgccaa tctgggcttt tactttcccg gtattggtgt cgataagggt ggaggcaact
     5641 tgcatctcgt cgtctgggta agagacatac tgatccgtgt tgacgatatc atatagtttc
     5701 ttttgggcgt ccagatccaa attcgtataa atctctaaac cgtctgtgta gacattctta
     5761 tctgtttttt cttgtacttc attgatgact tctttgacat aattatcgac gatcttagta
     5821 ttgtcatcgg attgagttag ttcttgcaga ccatccgtta ccggtacatt aacagcttga
     5881 tcatattctg tttgagagat tttttcgttt tgaagcatcg tatacaaaac agtatctcgt
     5941 cttttcttcg cctgatctgg ataaacataa ggatcatagg cggaaggggc ttgaggcatc
     6001 ccagcaagca atgctgtttg cggtaaagaa agttctgata atttcttacc aaagtacatc
     6061 tcagaagctg tctccatccc gtacaagccg tttgacatat acactttatt tacgtagtag
     6121 gtcaagatct cttgtttcga ttttttttgt tccaatctta cagccatcca cgcttcttgg
     6181 gccttgcgtt tcagagtctg atcctcggca ctggtggaga agaaggaaag tttgatcaat
     6241 tgctgtgtca aagtacttcc gccttgcagt ccgccagagg taaagttaga gagggcagaa
     6301 ccgatgatcc gaatagggtc aaccccgatg tgtttataaa aacggcgatc ttctaccgac
     6361 acgatcgcat cttctaatgt tttcggtaat tcattcgcag aaattttttc acgcttttct
     6421 gcgcctaaat cttcgaatag ttcgccatct tgtgtatata gtttggaaga tacggtagcg
     6481 tctaattttt tatccgtcaa ttcgggcgca tcttttgcgt aataccagaa aagtcctaca
     6541 cctgctaaaa agaggataca gaaaaatgag agtattccta aaaggatctt gataaataat
     6601 ccttttttat gtgttccaga ggactttcca gaacctttgc cagaattctt cttcacactc
     6661 tttttaggag taggctgttt ctgtcgtcta gagcttctag tttgttcatt tgccattctt
     6721 gctttctcct tcaatagata atgttgataa atagaagtca accgcgtcca aataaggaat
     6781 ccgcggagaa ataccagttt tgatctctat tcctagttct tcgatcaaag ataaaggtag
     6841 tgatttgcgt cctttttcct tttgggcgtc ccagtaagca atcaaatgaa cactattcaa
     6901 ataaaaacag cgcttcaaag acgaaaacca taacaagaca aagcagaccc cattttgttc
     6961 gaggcatgct ttcatatgtt cgatttgatg ggcatggaag tttttaaagg gaaaagatgt
     7021 tttgttcttg gtttcttttg cttcaaagtc caagtaaaag cctcgataga cgccattata
     7081 gtctgtagtt gaggcttggg taaagtaggc ttccttgatc acagcagcac ttctcttagg
     7141 atagtctact ttcacgattt ggataggggt aggcttttta tggataaccg ccaacccgcg
     7201 ggaaagataa tatttattac tttcattgat tgcttcttca aagcgcatcc cccgattgcc
     7261 gaattcagtg atctgatttc ttttttcttg aattttttcg acgggagagg cattcttata
     7321 ataaggttgg ccatttggat agcgcaatac catctttaat cacactccta ggccacatta
     7381 tagcaaaaaa gcggatagaa agaaaaggaa tctgagatgg ataagtcaaa agtaatctat
     7441 gtgtctgggt atcgaagttt cgaactcggt gtttttaaag aaaatgatcc taaaatccaa
     7501 gttgttaaaa atgttttaaa aaaagaactc catcagttag cagaagaagg gctggaatgg
     7561 gtacttgtca gtgggaattt gggcgtcgaa ctatgggctg tgcaaatagt agcggaattg
     7621 aaagaagaat atccggaact atctcttggt attttgtatc ctttttctga ttttggtaat
     7681 aactggaatg aagggaacca agaaaaaaaa caattagcag aacaattagc agattatgtc
     7741 gaagctgtta gccatcaacc ctaccaatca cctagtcagc taaagaatca cactcgtttt
     7801 atacttgagc atacagtggg ctgtctgctg atctatgatg aagaattccc tggaaaaacg
     7861 aagtattttt ttgaagatgc acagaattac caagcagatc atccctacga aattcggctg
     7921 atcagtatgg acgatcttca aaattttagt gaataatcga tattgtgttt gatttatcaa
     7981 cttttttcct atacaatgaa aaaggtagaa atgttattac gtaaatgaaa actagaggtg
     8041 taaatatggc gaatttggtt tatagtccta aagacatttt acaacaagaa ttcaaaacaa
     8101 aaatgcgcgg ctatgatccc gttgaagttg atgaattctt agacaatatc atcaaagatt
     8161 atgaaactta cagcaaagaa ctccttgctt tacaagaaga aaacgatcga ttgagtgcaa
     8221 aagtagctca attatctaaa actcaaggag cagctcaaac acgcgtgcaa caaacagagg
     8281 caccaaagag cgcagcagtg accaattttg atatcttaaa acgcttgtca aatcttgaac
     8341 gtgaagtatt tggtaaaaag cttgatcaac aagcaagtgc agtcaaacca gcacaaccta
     8401 atccaaataa ctacacaaat gcagacacaa gcttagatga taatgaaaaa acacgtcaat
     8461 tttaattttt gattaatgaa tttgcggttt tcgggtaatc gcggtctgac ttgatcaggc
     8521 tgaggaaagt ccatgctcgc acaggctgtg atgcctgtag tgttcgtgct tagcgaaacc
     8581 ataagctaag gtactctttg gagtaacggc aggaaaacaa gctaaggctt cggctatgct
     8641 taagtatcct tgaaagtgcc acagtgacga agcggctggg gaaacccatc cggtggaacg
     8701 cggtaaaccc ctcgagcgag caacccaaac aatggtaggg gcgctttttg tctggaagaa
     8761 gaacaggaca aaaaggcagt ataactgcag atagatggtt accgctttgt tttttctccc
     8821 tggaaaagca aagtacagaa catggcttat agaaaaccgc aaacatcagg gaattaggtc
     8881 gtgacaaaag taatgcgtta taagaaacaa gaaaaacatt tgaaagctat ttttcaatac
     8941 ttcagatgaa tcgttcttat tacaaaacaa acttttgtat caccggttat tcggaatttg
     9001 agtaaaagtg tggggtagga ctgatgtccc acctcctttt tttataaata aggagattgt
     9061 gtatggaaaa aaacaggaag ttcaacctcg tcgcaactgc ggcaagcggg ctagaagcac
     9121 tggttggtaa agaattaaga gatcttggaa tcgaatgcca agttgagaac ggacgtgcac
     9181 gttttgaagg aacaatggaa acgatcgcta cagctaattt atggttacgt acagcagatc
     9241 gagtaaaaat cgtggttggg gaattcgatg cgtatacgtt tgatgaattg tttgaaaacg
     9301 taaaagcatt gccttgggaa gattttcttc cactagatgc agcttttcct gtagctggaa
     9361 aatcgatcaa gtcgaaacta tatagcacac ctgattgcca agcgatcaca aaaaaagcaa
     9421 tcgttgaacg tctccgtacc tattatcacc gtccagcttc tgtaccactg acggaaactg
     9481 gcgcacattt tcagttggaa gtagctttgc tgaaagacca tgtgatggta actctggata
     9541 cgacaggacc aagtttattc aaacgtggtt atcgcttaga aaaaggtgga gcaccattga
     9601 aagaaaacat ggcagcagca cttattatgt tgacaaattg gcgaaaagac cgtccatttt
     9661 atgatcctgt atgtggttca ggtacgcttt gtattgaagc agccttaata ggccataata
     9721 tcgcaccagg attcaatcgt gagtttgctt gcgaatcttg ggattggttc agtcaagaaa
     9781 tcatggaaaa tgttcgatca gcagccgaag aaaaagcaga ttatgatatt gaattagata
     9841 ttactggttc agatatcaat ggacggatga ttgaaattgc caaagccaat gcagaagaaa
     9901 tcggattagg ctcttcgatt acctttaagc aacaagcagt caaagacttc aaaacggata
     9961 aagaatacgg ggtcatcgtg gctaatccgc cttacggaga acgtctagga gaagaagaaa
    10021 ctgttcggaa attatataaa gaaatgggcg atgtattccg tccattaaaa acatggagta
    10081 aatatatctt gactagcgac ttagcgtttg aggaatttta cggacaaaaa gcaaccaaaa
    10141 aaagaaaatt gtacaatggt gcattgcgta cggatctatt ccagtattgg ggaactcgtc
    10201 cgcctagaaa aaaagagaaa gacgaataat cttactaatt gattcattca attggatgtt
    10261 tggaggaata gggaatgaaa gaaaaagagt ttttacaaga agtaaaagaa atcaatcttc
    10321 tacaacaagc tttaggaatc ctcgattggg atacacaaac aggtatgcct gaaaaagcta
    10381 gtgcataccg aagtgaagta gacagctatc tttacagcat ttatttttca aaaaaaatcg
    10441 gtccaaaaat caaagaagcc attcgctatt tttctgaaca tccggaagaa ttgtcggaag
    10501 ttggaactgc cgtttttgcc aaagtaaaag aagagtatga tttggaacat cgcgtaccgg
    10561 aagatcttat gagaaaatat acagctgccg tttcttcagc acacggacaa tggcaaaaag
    10621 ctagagaaac acaacaattt tctgattttc aacacgcatt gaatcaaaat attgaattaa
    10681 caaaacagtt gataccttac tggagaaaag atgaaaagac gaattatgat gttttgctga
    10741 atcaatacga acccgggatg actgtcgaaa tccttgataa ggtatttgat cagcttaaag
    10801 aaggaattct ttcgatccgc cgtacgctcc aagaaaaagg gactgaacct gaaacagact
    10861 ttttaaatcg gagaatgacg aaaaaacaac agaagagatt tgtagtgaaa gtaatcgaac
    10921 aacttggtta tgattttagt cgtggtcgtt tagatgacac tgtccaccca tttatgactg
    10981 gaattaatcc gaatgatgca cgaatcacga cacgatggaa cgaaacagat ttcaaaatgg
    11041 ctgtttttgg agtgatccac gaggctggtc atggtatgta tgaacaagac atcgatgata
    11101 aatatgcgta tacaccggtt tatgaaggta catcaatggg tatccatgaa tcacaatcgt
    11161 tgtttaacga gatcattatt ggaagtagtc gcagcttctg gaaaaagcaa tatcctttct
    11221 ttcaagaatg tgcagaagga acattcgatg atattccttt tgacaaattt tatcgttcat
    11281 tgaaccatac aaaatcaagt ttggttcgta tcgaggcaga cagtttgact taccctctcc
    11341 atatcatcat tcgttatgaa atcgaaaaaa tgattttcaa tgaaggggta gatgttgctg
    11401 aactacctga aatatggaat caaaaatatg aagagtatct gggaatacga ccaacaaatg
    11461 atgtggaagg catcctacaa gacgttcatt ggtcaggtgc aagctttggt tattttccct
    11521 cttatgcatt agggtacatg tatgcggcac aattacttca ttctttgcag caagaaatag
    11581 atgtggaaaa tgttctagcg tcagacgatt attctccaat caaaaactgg atgtcagagc
    11641 atatccatca atatggtgca tctagaaaac caaatcaatt aatcatggat gcaacacatg
    11701 aaccgcttaa tccgcaatac ctgatcgact atatgaaaga cctgtatttt aatgtatatc
    11761 aggtaaaata aaatacaatt tacaaagata gctgaaattc atctaatcta tagatgtttt
    11821 cagctattta cttaagaaag aagtggaacg aatggataaa ttacaagtga tcgctgatta
    11881 tagtatggac caattagcgc atgatcaaac aggacatggg agcgatcata ccaaaagagt
    11941 tgtcaagtta gctgaaaaaa ttttggagac ggaaccgcag gcagaccgct ttgtgacgct
    12001 tgcagcagct tacctacatg atacgattga tgataaagtc gttaaaaatg agaacgaggc
    12061 aaagcaacag cttcgtgtat tccttcgctc tttgccaata gtagaggaac agatctcgat
    12121 gattttttcc attatcgaaa atatgtcctt ttctaaaaat ctctctgaag cggccgaact
    12181 atctctggaa ggtaagatcg ttcaagacgc tgatcgtatc gaagcattag gagcaatcgg
    12241 cattttgcgt actgcttatt tcggcggtgg acatgggcac ccgatttttg atcctgaact
    12301 gtatccgcaa acattcaagg acaaagaaaa ttaccgaaaa ggcacgacag tgatcaatca
    12361 tttttatgaa aaactgttct tgctgtctga taaaatgaat actgattacg gatatgaaga
    12421 agccaaacga agagaaacct tcatgcgtga attcttagaa gaattttttc tggaatggtc
    12481 tattgacgat gaaaatttta ctccagacaa ttggatcaaa aataacaaaa aatgatggag
    12541 gttgtgacag aagtggtcag ctccaagata tttcggatca ttttccgtaa aagttacttc
    12601 tggaacactg tttaccaaga ggtcgtgagc ctgccgttca gctccgagtc acaaggaaca
    12661 atttcaaaaa atagcttctc gtgtttgatg aatattgtaa cttgtgattc ggaattggca
    12721 ggagaacacc gtttatt
//
LOCUS       DACBYO010000085        12735 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.085, whole genome shotgun sequence.
ACCESSION   DACBYO010000085 DACBYO010000000
VERSION     DACBYO010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.085"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="IVD26_002301"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="IVD26_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAP6080232.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="IVD26_002302"
     CDS             complement(323..892)
                     /locus_tag="IVD26_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAP6080233.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="IVD26_002303"
     CDS             1078..1980
                     /locus_tag="IVD26_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6080234.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="IVD26_002304"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="IVD26_002304"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAP6080235.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="IVD26_002305"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="IVD26_002305"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAP6080236.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="IVD26_002306"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="IVD26_002306"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAP6080237.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="IVD26_002307"
     CDS             8548..8733
                     /locus_tag="IVD26_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAP6080238.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="IVD26_002308"
     CDS             complement(8795..9991)
                     /locus_tag="IVD26_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP6080239.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="IVD26_002309"
     CDS             complement(10161..11597)
                     /locus_tag="IVD26_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP6080240.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="IVD26_002310"
     CDS             11890..12699
                     /locus_tag="IVD26_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6080241.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3802 a         2673 c         2250 g         4010 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgaca
//
LOCUS       DACBYO010000086        12624 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.086, whole genome shotgun sequence.
ACCESSION   DACBYO010000086 DACBYO010000000
VERSION     DACBYO010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.086"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..2175
                     /locus_tag="IVD26_002311"
     CDS             <1..2175
                     /locus_tag="IVD26_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP6080242.1"
                     /translation="FDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSGGYR
                     YPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDFRYD
                     SYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVIIRST
                     QLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLDSKR
                     GSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGINSFN
                     FGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLINNWE
                     ATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLACGLE
                     NLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDFSRQ
                     DVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLYEFL
                     EKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVYPIS
                     SMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAFYKK
                     HRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLAGLA
                     EEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            2236..3456
                     /locus_tag="IVD26_002312"
     CDS             2236..3456
                     /locus_tag="IVD26_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HAP6080243.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            3453..4913
                     /gene="gtfA"
                     /locus_tag="IVD26_002313"
     CDS             3453..4913
                     /gene="gtfA"
                     /locus_tag="IVD26_002313"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HAP6080244.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            4990..6096
                     /locus_tag="IVD26_002314"
                     /pseudo
     CDS             4990..6096
                     /locus_tag="IVD26_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            6418..6627
                     /locus_tag="IVD26_002315"
     CDS             6418..6627
                     /locus_tag="IVD26_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP6080245.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            6620..6769
                     /locus_tag="IVD26_002316"
     CDS             6620..6769
                     /locus_tag="IVD26_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HAP6080246.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            6804..7588
                     /locus_tag="IVD26_002317"
                     /pseudo
     CDS             6804..7588
                     /locus_tag="IVD26_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922412.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(7872..8957)
                     /gene="xerS"
                     /locus_tag="IVD26_002318"
     CDS             complement(7872..8957)
                     /gene="xerS"
                     /locus_tag="IVD26_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAP6080247.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            9291..9524
                     /locus_tag="IVD26_002319"
     CDS             9291..9524
                     /locus_tag="IVD26_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HAP6080248.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            9521..9928
                     /locus_tag="IVD26_002320"
     CDS             9521..9928
                     /locus_tag="IVD26_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP6080249.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(11065..11583)
                     /locus_tag="IVD26_002321"
     CDS             complement(11065..11583)
                     /locus_tag="IVD26_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HAP6080250.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            11950..12198
                     /locus_tag="IVD26_002322"
     CDS             11950..12198
                     /locus_tag="IVD26_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080251.1"
                     /translation="MVKLKMLYIGLQHRSFFDCALGKKYYEVKIDDDTFLTAHQMKQL
                     QKRNDQLEENLILKKRLPYSRLARRTIKGQDLPEDHPF"
BASE COUNT         4333 a         1986 c         2265 g         4040 t
ORIGIN      
        1 tttgacaatc acacacaaac atttcattta caaaataaaa aaattagcta tctattagga
       61 atcgaagaaa ataattattt aacgcatctt tattttggaa aaaagattac gcactattct
      121 ggtgggtatc gctacccccg aacagatcgt tccttctcac ccaacaatgc aaatgcgcaa
      181 gatcgtttat tatctttaga cacattacca ttagaatttc caggatatgg acatggtgat
      241 tttagagaac cggcgcataa tattaaatta ggaaacggta gtcgtgtaaa tgattttcgt
      301 tatgatagct acgaaattca aaaaggaaag cccagcttag cgggattgcc agccttatat
      361 acggaagatg atgatgaagc tgaaacgctg attattcaat tgaaagacgc gattagtgga
      421 ttgactttac agttgttcta cacaatttat caaaatcaca gtgtaattat tcgttctacg
      481 caattagtaa ataatagtga tgaaacagtg gagattaacc gcttagctag tcaatcaatt
      541 gattttccaa atcgtccact cgagttaatt catttaaatg gtacctgggc aagagaacgt
      601 caaatgacta gagaaaaaat tcatacaggg ataaaagtat tagatagtaa acgcggatca
      661 agcagccatc aacaaaatcc gtttgttgct ttagtagatg ccaaaacaga tgaatttcaa
      721 ggagaggcat atggatttaa tttagtttat agcggtaatc acgaaacggt gattcaaaaa
      781 gatccatttg accaaacacg ggtcattatg ggaattaatt catttaattt tggttggcaa
      841 ctaaaaactg gcgactcatt tcaaacgcca gaagtcgtga tggtttatag taatgaaggt
      901 ctgaatacgt tatcacagac gtatcatgaa ttgtataatc accgtttaat tcgtggaaac
      961 tatcgtttaa aagaacgtcc cacgttaatc aacaactggg aagcaacgta ttttgatttt
     1021 aacgaagaaa aaatcatgaa tattgtcgat gatgcgaaga acttgggcat tgaaatgttt
     1081 gttttagatg atggttggtt tggcggtcgt gaaaatgact tcacttcatt aggtgattgg
     1141 gttgaaacag aaggcaaact tgcttgtggt ttggaaaatt tagccaagca agtgcatgat
     1201 aacgggatga aatttgggat ttggtttgaa ccggaaatga tttctgaaga tagtgaacta
     1261 tttcgagcac atccagattg ggcattgggt attccaggtc gtgaccgctc aattagtcga
     1321 aatcaatatg ttcttgattt ttcaagacaa gatgttcgtg ataatatcta tcaacaaatg
     1381 acggcgattt ttgatcgtgt accgattgat tatgtgaagt gggatatgaa tcgaaatatg
     1441 acagaagtct attctgtctt gttggactca acgatgcaag gtgaagtggc tcatcgttat
     1501 atgttagggt tatatgaatt tttagaaaag ttaacaacga attatccaac tattttattt
     1561 gaaagttgtt cgggtggagg cggtcgtttt gatgcaggtt tcttgtatta catgccacaa
     1621 acttggacga gcgacaatac cgatgccgtg gctcgtctga aaattcaata tggaaccagc
     1681 ttagtgtatc caatttcaag tatgggtgcg catgtttcag cagtcccaaa tcatcaaaca
     1741 ggaagagaaa cgagtttaac tattcgtggc aatgctgcga tggctggtgt ttttggttat
     1801 gagctagatc taacgcaatt aacttctgaa gaaaaagcag aaattaaaga acaagttgcc
     1861 ttttataaaa agcatcgcca acttttgcaa tatggaactt tttatcgctt ggaaagtccg
     1921 tttgaaggca atgatactgc atggatgttt gtctcaaaag accaaacaga agccatggtc
     1981 ttttatttcc gagtattagc agaagctgcg catccattag tcacattgaa attagcagga
     2041 ttagcagaag aagcaactta tcaaatggaa gatgtaacat ttgctggcga tgaattgatg
     2101 aatctcggtt tttatattga ctcagaacta catggtgatt atgcgacaca acgcttttat
     2161 ttgaaacaga tatagtagct tgaatttaca atataagtgc aacaccaaaa gagactcatt
     2221 ccaaacgaag aaaatatgtt ttatttacac gcatttacta aaaagcagcc tgatttgaat
     2281 tgggaaaatg aagaagtacg tgaagaaatc tatgcaatga ttaactattg gttagataaa
     2341 ggactaggcg gatttagaat cgatgcgata ttaaacatca aaaaaaaact agagtatggc
     2401 atctttgaat ctgatggaga agatgggtta gccttcattg ggccctggat tcttaatcag
     2461 tcgggcattg aagtgtggtt aaaagaaatg agagagcgga catttaaacc acataatagt
     2521 atgacggtag cagaagccga tgttcctaat gaacgtttag atgaatatat tggtgaagat
     2581 ggctattatt cgatggtttt tgattttagt tatacggata ttgatgtacc tgaaactggt
     2641 gaatggttta aagatagcca atggacatgg acggatatgc gtaccaatat ttttacgaat
     2701 caattagtta cgcaagataa aggttggggc gccttatatt tagaaaacca cgatcaacca
     2761 cgttcaatta ataaatatat tccagaagaa tggatcaatg attatagtaa aaaaatgttg
     2821 gcgacgcttt ttatgttact aagaggtacc ccttttattt atcaaggaca agaactagga
     2881 atgaccaaca tagaaatggc atcattagaa gattttgatg atgtagctac gcattctcag
     2941 tataaacggg cattagaata tggattggca ccagagcaag cattgaaagc tgtcaataaa
     3001 cgaagtcggg ataattctcg cacacctatg caatggaata cgcaaaaaaa tgccagattc
     3061 tcaacttctg ataatgtatg gttaaaagta aatcctaatt atccagaact caatgcagaa
     3121 gctcagttaa ccaatcaaca gtcggtattc aattattatc atcaattaat taaattaaga
     3181 aaaaatagtg tatacaaaga cgtgctaatc tacggacaat ttctaccagt gaaagataaa
     3241 aatgaacata ttttgcttta tgaacgccaa ttagaagata aaatcgtatt agttatctta
     3301 aacgttacag caacagaaca agaatattat gtagatgaac agtaccaaca agtattaatc
     3361 aataattatg aagatgtttt attagatcaa agtcgaaaat tgcgtttacg accgtttgaa
     3421 agtattgtat tagctaatta tggaggacaa ttatgaaaat taaaaacgaa gcaatgctca
     3481 tcacctatgc agatagttta ggaaaaaaca tgggcgaatt aaaacaagtc ttagacaaac
     3541 atttacaagg tgttattggt ggtgtacatc tgttgccttt ttttccatcg acaggtgatc
     3601 gaggctttgc gccgagtgat tatacgacag ttgatccagc tcttggaaca tgggaagatg
     3661 tggaagcatt aggtgaagat tattatttga tgtttgattt tatgattaat cacatttctc
     3721 gtgaatcaaa atttttccaa gatttcaaaa aaaaccatga gcagtcacca tacaaagaaa
     3781 tgtttatccg tattcatgaa tttttcccag aaaatcgacc aacacaagaa gatattgatt
     3841 taatctacaa gcgtaaagac aaagcgccgt ttcaaacggt agaatttgcg gatggtacga
     3901 cagaagaggt ttggaatacc tttggggaag aacaaattga tttagatgtg accaaagaag
     3961 ttgtgaaaga atttattcga gaaaccatca aagatatggc gaaccatggc tgttctttaa
     4021 ttcgattaga tgcgtttgct tatgcgatta aaaaattaga taccaatgat ttcttcgtgg
     4081 aaccagatat ttgggaactt ttagacgaag tgcgtcaaga agcagcgaaa tatgacgtcg
     4141 aattattacc agaaatccat gagcattatt ccattcaaat gaaaattgcc aatcatgatt
     4201 attatatcta tgacttcgcc ttgccaatgg tcactctgta ttcactttat agtggaaaat
     4261 cagaacgttt agccaattgg ttgaaaatga gtccgatgaa gcagtttaca acattggata
     4321 cgcatgatgg aattggtgtt gtggacgctc gtgatttatt aacagatgaa gaattggatt
     4381 acacctctga ggaattgtat aaagtcgggg cgaatgtgaa gaaggtctat tcaagtgcca
     4441 attacaataa tttagatatt tatcaaatta acagcaccta ttatagtgca ttaggcgata
     4501 atgaccgtag ctatctgtta gcacgtgcga ttcaagtatt tgcgccaggg attccacaaa
     4561 tttattacgt tgggttatta gcaggaaaaa atgatattga actgttggaa gcaacgaaag
     4621 aagggcgtaa tattaatcgt cattactatg atttagccga aattgaagaa gaagtgcaac
     4681 ggccagtgat tcaacaatta tttgcacttt taaaatttag aaatgaatct gcggcgtttg
     4741 atttggatgg aacgattgaa gtagcaacgc catcagaatc agaaatagtg attacacgta
     4801 aaaataaaaa cggtagtgat agtgcaacat taacggctaa cttggatacg aaagaattta
     4861 tcattgagtc taaagatata aaaattttca ctagtgttgc attaaaattt taacctattc
     4921 catagaacaa aaaatccttt atactagcac ttggatgact tatccaagac caataaaaag
     4981 gactcataca tggataagta taaaacaaat acagcattta ataaatggtt ttctgccata
     5041 aaattaggaa aactttctgt caactcccaa aaatgtattt ttgattacaa ttcgtatcgt
     5101 aaaaaactgt cttttgaagc tgtgctcaag ctctttctct acgcagttaa tgaagaaaaa
     5161 gaaagtttgc gtgatttgag tacagctctt atcgaccgat cgctccaact agaaaccgat
     5221 gtgtcatcga ttagtcatac ccaattgtct cgagcattta atgcacttga acctaaagtg
     5281 ttagaagaaa tttttcaaca actgttagaa aaagttcaac atcaaatcaa accaaccaag
     5341 cgaaatcatc tgtatctgat tgattccagt acgttttcgc ttagtttaaa acgtcataag
     5401 tgggcgactt tccgtcaaac aaaatcaggt gtcaagttac acttaaacta ttgttatatg
     5461 gacgatacta cgatgtatcc aactgatttt accttaacaa atgcccatga acatgatctc
     5521 aatcaactac cagtattggt gaatcaacca gaggcaactt acgtgtttga tcgtgggtat
     5581 taggactttg aaaagatgga tcagatgcat tgggatggct atttcttcgt cactcggatt
     5641 aaaaaaaaca ccaaagttca cgtgatagat actctggaaa catcgccaga aacagaaatt
     5701 ctacgagacg agctggttcg tttaggatct aaaacctatc taaccgccaa tttccgacta
     5761 gtcactgttc aagataagaa cggacgtgtg tttcaattta tcaccaatcg aatggacgtc
     5821 tcttcaaaag aaatctctga tatgtatcac gctcgttggc aaatcgaatt gtttttcaag
     5881 cacatcaaac aacacatgac cattaaaacc ttcttttctc aaagtgaaaa aggcgtgcag
     5941 aatcaattga ttttaacgat gatttccgct ctcctcacgt ttctcatcaa attggagacg
     6001 aaaacggaaa aatcagtgtt ccaaatcaaa cgattctttc gttatttact gtttcagccc
     6061 tttgaatgtt gtctagaaaa attaattccc acatgagaaa aaagaaattt ggctcgttac
     6121 ttttggtttt cagttgaata acagataaaa aattttctgg aaaaagtcat cctctgcgtc
     6181 agcacagttt tttttgactt attttcagag gaaatagttt tcagaatatt ctaaaatgtt
     6241 ttatgcaaca ctagtgatat tttttagaat tagatttcta atgtgcattt tttgagtatt
     6301 aaggagcaag tatacaaaga tttataaagc tgattaaatt tgaataaaaa tatgcaggaa
     6361 cgctactatt tttagtagtg ttctttttta tatttgaata aaaaatgtgg tggttaaatg
     6421 gtggttataa caaaaaatga attaatgaaa ttaggttatg ggaagtatca gtctgagaga
     6481 atcatacgac aggcaaaagc aattatggtt tcaaaaagct atacctatta cgaaaataga
     6541 agattaggac tagtacctgt tgaatctgta gaagaagttt taggtatgaa gatagaggta
     6601 gaggaggatt ttcagaatca tggttaattt taaaaaagat aaaaatggga aatatcattt
     6661 tactgctagt ttgggattcg acaaacgaac agggaaaaga gtacaaaaaa acgtagaggg
     6721 gttaaaacag ttaaagaaga aaaaaagcgt ataccgaact tgtttctaat tatggaaaag
     6781 aagcagaaac ttctcaaagt actatgttgt ttgaggagtt tttttataaa ttattcctac
     6841 cttattatca agggaaagta gaagaaagaa catataaaaa tcggttatct acaatcaaaa
     6901 aaacttttct tatttcttta aaatggagtt aagagaaata cgtccaattg acattcaaaa
     6961 gtggcaaaat aatttattga gcaaatataa aaattcttat gtaagaaaca tgtatgggat
     7021 ttttcagatg tcattagatc gagcagttgt tttgggacta cttgaaaaaa atcctgcaaa
     7081 agttattgga aatgtgaaga aaaggaaaac tacagttgat ttttggacaa aagaagaatt
     7141 tacaaaagtt atttcaactt tttatattga tgatttgtac caacattttg gttttatttg
     7201 tatgtggtta ctttttatga ccgttatgcg tttgggagaa gccactgcat taacttggaa
     7261 agatattgat tttgaaaata aaaacttgcg tgtgaataaa acactctatt ataagagagc
     7321 caaaacctat gagtttgtag aacccgaaac ggcttctagt attcgtacaa tcgaactaga
     7381 cgacaataca attacctttt taaaagcttg gaaggagcgt caagtttcaa taggaggcat
     7441 gtcgtttgta ctttcttata atggaacacc tactcagaaa tatacaatcc gtcatattat
     7501 gagaagacat gcaacgatcg ttggtgttca tataatccgc atacacggat taaggcatag
     7561 tcatgcttct ttgcttatat cacaataaaa agatgcactt cgaattaaag aaaggttaaa
     7621 acatgctgat gtacaaacga ctttaggaac ttatggtcat ttgtatctaa attcattgag
     7681 agagataaca aatgatccca cagattatat ccaaactaat ttttctaaaa tcaaaccgac
     7741 acctatttac gataataaaa aataaatgat aaacaaaagt aggatcacac caaaagaaac
     7801 acactagaaa aactataata caggcttttc tagcgtgttg tttcttattt ccgcctattt
     7861 atacattata ctcataaagc atttaatgca tcgatcgtag ccgcattgtc tatatgggta
     7921 tataaagttg ttgtattggt acttgaatgt cccaattgtt gggcagttaa taccaatgaa
     7981 tttgtctgtt ggtagagtct agtagctaat gtatgacgca gtttgtgagg gctgacttga
     8041 attctaaagc cttttgaata ttttgctacc atccgttcga ttgcaatacc ggatatacgc
     8101 ttggcttctc cttggtaaat tgctagaaat aaagcttttt cgttttctgt tactttatat
     8161 cgttctttcc gaatagctag ataattagct aaatattcca ttgcgaatgc tgctatattg
     8221 acagcatctc ttttatttcc ttttctagtt actaccacat tattcttatc taaagatagg
     8281 tcatctaaat taatatttat aacctcggag agtctcaatc cagatcctaa aatcagtgca
     8341 ttgatcgcca ggtctctttc tacatctcgt tgataataga tcaaagctcg tttactcaaa
     8401 gtatttttat attcattggc aatataatct agataatttt gtgtatcctt atctagaaat
     8461 aattttttct caatggcatt ggcacgtgca gctaacgtag ttttatctgt gatggttgct
     8521 acttgatcca taggattatt gtctaagtat ggttttccta gaggattatt ggaacttttc
     8581 gaaagatatt taaatagaac ctttaatgcc gtgatatttc tattgatagt agaagtagat
     8641 agacctaagt tattattatc tttgagctta gtttttgttg tctctttttt tacattttct
     8701 tttgtgcgac gtttcaaatg agatttgtac aagtttaggt cataggcagt taactgtctt
     8761 atcgaggtga tagaagtatc aggaacgata gactcactca gaagccattc ataaaagagc
     8821 ttataatttt ttagatattc taaagtggtt cgaggtgatt gatctttatc ctcacgatct
     8881 tgaacaaaat cttttatata atcgggcata tgaagtatga ttgtatctat tttttgatat
     8941 atttctgtat ttttcatgtc attcatcctt tcaataagta ggggagaaga gtatctctat
     9001 aattggacta taccaattat agaatgtttt gtcaattggt atgctctaaa atttattaat
     9061 ttgtttcaaa aaaagcatat aaacaggtat acgtttaata atttaaaata aatggtatac
     9121 ataaataggg aaggaaatag aagggagcaa tctaaatttt ttgaattttc ttaattaatt
     9181 atatagaaag aacaatcttt ctatagagtt agacatgaga gggactatgc ttgatttaaa
     9241 atcaacaagc gtatatactg tatatacaaa gaaaaaggag ggagaagact atggcaatta
     9301 aagaaagaaa atttagggaa gtggggaact cagtagtatt aactatttca aaggagtttc
     9361 ttaaagaaaa tgggttaaat cccggagata cggttttttt agatgaagaa aaacttcgag
     9421 cggcaattac aaaaaaacaa gccttatctg atgaaattga tttagcaata tctcaagcat
     9481 taactgaata tgatactact tttagagagc ttgtcgataa atgagtattc attacctaga
     9541 agccaaagat attataaaaa tgaatgtaat ccaaataaaa aaatactctc ctaatgaacc
     9601 ccttggtgta aaggatgcga atgctttaga aatgtgtgta gggcaacttc gagcctcagc
     9661 ttttggtgaa gaggtttatc cttcgattta tgaaaaagca gctatcctac ttatacaatt
     9721 gataaagaaa catccttttc acaatgcaaa taaacgtact gctttcttag ctacttttgt
     9781 ctttttgaaa atcaatggac agcttttagc tattgatcaa aaagatgctg taaatttagc
     9841 ggtatatatt gctacgtatg ataaggattt cgatcaacta aaatatgaag tgatcaacac
     9901 tataaagaca catacgcagc ccatttaagg agttactgta tgtgtcttta tagggttatt
     9961 agctgctata gcgaaataat tgaagtaaat tacaaatagc tataattcaa atccaactat
    10021 atagaaaacg taaattttct atatagttgg attaagataa cgactattta ttttatcata
    10081 tttttactat accctatact tttacttggt atatttatga ataatcgcaa atttacccct
    10141 atactactag tttgtaagtt agattaataa aaatactaaa gttatttgtt cttttattaa
    10201 atacacctac aacttataaa ttgatggtat ttagataaca cgaaagaata aaaataacag
    10261 ctgatagtaa agtttgttga cgattgctac tcaatcgaaa gtgagttagt gcgtatgaac
    10321 ttgcttctga aaacttatga aatgaaagac cttttacatc ttgcagaaat cgttactggg
    10381 attaaactaa gcaataaaaa ctaatgttcc cctcattctt tgaacttcta ctatttgatt
    10441 tatttattct gataaatgac gatttcacct tcaggatctt caaatcccgt atagaattta
    10501 tttaagatct cttcagtatc agtaatagga taggcgatag gccacatacc ctttgatggt
    10561 tagaataaac tgctcaaaat ctgtatcgta tgttggcttt agcatattaa caaaggctat
    10621 ctccaaatta taaaccataa gcgttgaatc gttcttaaca atttcaattc ttcctaaccc
    10681 aaagtcagaa gatataatta ccggacttgc cttacccttc atgtgggttg ttgagattcc
    10741 atatttaaag ggaattgtcg gtactatcgg cggtctgaaa aacatcccaa aaataaaaaa
    10801 atctttcccc tgctagtctc ctaagtccct ttgtagcgga tatggcacca taatctcatt
    10861 ttatcgaagt gagtcatggt ttatctgttg gccaaccaaa attgatacaa tctaacgatg
    10921 caccctctac ggcattctag gggagtgcac ttgcattcac ccaataaaaa ccggcagtta
    10981 gcaaagaact tatgtagtcg tatgttctta ctgttaacat acaagaggtc tcctttccac
    11041 aattgcttag cagtaaacgg gaatttacaa agctaatctc ttccattttc ttatctttgt
    11101 tctaaaagtc ccaaatggag caactgtatt tacatgaata aatttatata cttcccatac
    11161 agccgttttg gttgcctcgt ctgcccattt tcttttgtgt gcagtgaata gatcttcatc
    11221 actcattgaa tcaatcatca tgttaatatc atcaatatta cgattgagaa tttcctctaa
    11281 ttctttcaat ggtagatgtg cataggtatt tgtaaaccac ttatataact ctcctaactg
    11341 attccattta aattgatcag aaggcgtttt aacagataat ccatttcttt catcattttc
    11401 ccattttaga attaaattcg tccaaccaac ttgatatgct aaattttcag caggtgttct
    11461 atccacttcc tcaactcttt tatccttcaa ttcttcagga atagtttcaa attctaaaat
    11521 atatttagta taagtcctat ttatttcttt ttttaattct tctttatttt tatatgttct
    11581 cattatatta cctccataaa ttcctaattg tctcctttaa ttcatctata atttcatcca
    11641 cgatatttta atccgttcta caatgcatat ctgatatgca ttgactgtct aactcatatg
    11701 tgaatgattt ataaaatatc ccaacgtctc atctaaagaa atgttgatcg tcagcaagga
    11761 gctaaaaaat acgaatatat ttcttttgta gtaaaatcgg actggtttgc atatcatttt
    11821 cttcgtaaat atcaaaatca tgttaactac tatcaattac taataaaaac taccacttta
    11881 agcgttaaga actgttaagt ttagttaagt gaggatagtt cacaaaatcc attgttaaac
    11941 ttcacgaaag tggtaaaact caaaatgctt tatataggat tacagcatcg ctctttcttc
    12001 gattgcgcgt tgggtaaaaa atattatgaa gtaaaaattg acgatgacac gttccttacg
    12061 gctcatcaga tgaaacagct acaaaaacga aatgatcaac tcgaagaaaa tttaattcta
    12121 aaaaagcgat tgccatattc acgcctcgct cgacgaacta ttaaaggtca agatttacct
    12181 gaagatcatc ctttttagga aattgaagct ttttatgttg cacaatgcat ttataatact
    12241 acaatgatgt tttcaccaga tattcttcta gggtgcggtg taatgaaaca gatacacttg
    12301 caaaagaaaa ttcaccgcga atttactaaa attatgaata attatgttaa tcttccgaaa
    12361 tttttttcca aaattaaggg atcaagctgg tgttatagat tgtttaaggt tggcaaaaaa
    12421 ataacttctt tttaaacaat tatagaaaac cgatactctg ttaagttggt tgacacggtg
    12481 tcgattttta tgactttctt attctgaaac ttcactaacg gacagtacct aaaaagtcta
    12541 tagtatggac gtttacgagt actattttat caaaaatgct gctcatttca acttatatgt
    12601 tttagtgaac tacccccact tagc
//
LOCUS       DACBYO010000087        12476 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.087, whole genome shotgun sequence.
ACCESSION   DACBYO010000087 DACBYO010000000
VERSION     DACBYO010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.087"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(552..2165)
                     /locus_tag="IVD26_002323"
     CDS             complement(552..2165)
                     /locus_tag="IVD26_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAP6080252.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2306..3214)
                     /locus_tag="IVD26_002324"
     CDS             complement(2306..3214)
                     /locus_tag="IVD26_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6080253.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3397..4521
                     /locus_tag="IVD26_002325"
     CDS             3397..4521
                     /locus_tag="IVD26_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP6080254.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4546..4725
                     /locus_tag="IVD26_002326"
     CDS             4546..4725
                     /locus_tag="IVD26_002326"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080255.1"
                     /translation="MNKINENTSNTVLPATYSDATSYLTTAAYNYWQTGDFENSYLKE
                     AENFAHKYGVKLTGD"
     gene            4748..5665
                     /locus_tag="IVD26_002327"
     CDS             4748..5665
                     /locus_tag="IVD26_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6080256.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5658..6491
                     /locus_tag="IVD26_002328"
     CDS             5658..6491
                     /locus_tag="IVD26_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6080257.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6574..7692
                     /locus_tag="IVD26_002329"
     CDS             6574..7692
                     /locus_tag="IVD26_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP6080258.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7686..9584
                     /locus_tag="IVD26_002330"
     CDS             7686..9584
                     /locus_tag="IVD26_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAP6080259.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9578..10801
                     /locus_tag="IVD26_002331"
     CDS             9578..10801
                     /locus_tag="IVD26_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAP6080260.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10887..>12476)
                     /locus_tag="IVD26_002332"
     CDS             complement(10887..>12476)
                     /locus_tag="IVD26_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP6080261.1"
                     /translation="PAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYD
                     QKIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIV
                     SHDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLE
                     DFVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIED
                     AAIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNV
                     TIGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGG
                     EKARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINR
                     IATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSK
                     EQQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQ
                     DQETKLTEWEELSLELEEYEN"
BASE COUNT         4068 a         2049 c         2425 g         3934 t
ORIGIN      
        1 ttaaataaat aggaacaaaa aaattaaatt atttaataca cacattaggg atcattcatt
       61 gaaggattag aagacaacga ggatggcgaa aaatatgatt acaatagaaa agtcgttcta
      121 aaccaatcag ttcctagtat cacacaacgc aagccagtcg atttggtgag attagaggag
      181 tgaaagcaaa ctttattata taagaaaaaa tattcgaaag ggatgctagt ttaggtacta
      241 gtgctgatag attaatatga tgcctcgtaa tattaggcgt agttactcta gagacatcac
      301 tatggactat gatttgtctc agagtcacaa catgtttttt tatgaaaaga aacagctaaa
      361 ataattaaat tgcgcaatgt ttaaactttc ttaaactata acctaataaa tgtgaagaaa
      421 taatgcacaa tttcttcaca tttatcttct attctatata cataccaacc aacaacccta
      481 tatacttttt catttttact cctcaagtaa aaataactcc tagaccgcgg ctacccaccg
      541 cggtcgtttt tttattcttc aatcaaaatc gctttgatac ccaaacctgc caagattcgg
      601 gcagaagtat aagtattcaa tcctcttctg aaagtaatgt aaactttttt atcttttggg
      661 atttcattga ttcgatctcg taactcattc attggaatat tttttgttgc cgagatactg
      721 ccagaaggtg ctttattagg ttcacgtata tctaaaaaga acgcttcttt caaatcgttt
      781 tcgggtatat cacttgcttt gatcgtttct acgatattcg tcatttgatt gattgcgaca
      841 taaccagcta tattcaacgg gtcacgggta gtagaatacg gtggagagta aggcaactcc
      901 aaatcaggca aatcaaagac tgtcaagttt ccggtgattg ctacagaaag ttctcccatc
      961 cgtttatcga cacctttttc tccaaatgct tgtccaccta aaatacgacc gctatctgca
     1021 tcaaaaatca gctttagatt taatcttgta gcttctggat agaaataggc atggtcaaag
     1081 ggagtgataa aaacagtttt ataatttgtt atgcctgatg cttttaattc atgttctgtc
     1141 attcccgcat aacttgctgt atgatcaaag atttttgcga cacctgcacc aatatatccg
     1201 cgatagcgca taggcgtacc atttaaaata tctgccagca tatgtccttg acgattggcc
     1261 gcactggaaa gcatactttg gatcggctga ccagtcacta cactagtcgt ttcgataata
     1321 tcgccaatcg catagatgtc cggcagattg gtttgtaact ggtcatcaac aatgatctga
     1381 cctgtatctg ataattgtat gccggttgct ttcaccactt cattcttcgg agaaacacca
     1441 acagcaaaaa ttagcatatc agcagaaagg acggagccat ctgataatac tatttctcga
     1501 cctttatcac ggatctcagt aactcttgtt tctaaatgaa cggctaatcc ttctttcagc
     1561 aatttgtcat aaactaaatt agcaatttct ggatcataag ggaaagcgac ttgtggcaat
     1621 tgatcgatta aagtcacgtc taagccgcga tgcttgaaat tctcagctaa ttccagaccc
     1681 ataacacctg caccaagaat gacgacatgt tgtggatttt tttcttcaag gaacgatttg
     1741 attcgatccg catccgtcac actacggagg acaaagccgt tttctgcttc aaaaactccg
     1801 ggaatatccg gataatctgg tctagcacca gaagagatga tcaacttatc gtaatctgtt
     1861 tttatttctt catttgtgga taggtcttta actgttaatc gcttagtaga aggatcgatt
     1921 gctgttactt cgtgtttagt aaagacatcg atgttgtttt ttgttttcaa tatttctggt
     1981 gtacgttcga tcagcgagtc acggtcagtg atcacacctc ctaaataata aggcaaagca
     2041 caacttgcat aagaaatatt ttctccgcgt tcatagataa tgatttcgtg cgcttcattc
     2101 aatcgacgga aacgagtggc aaatgaagga ccgccagcta caccgccaat gacaacaact
     2161 ttcataaaaa catctccttt tctacgttga tcgtactatg ttatggtaaa aaacagcaaa
     2221 taattgtgcc ggaaaattat tgtttatttt gaatagacag aaaatataga gaaataattt
     2281 gtggataaaa cctaaaaatt tttttctatt ttaaggatag ataatacttt gaaggggata
     2341 accctgtata ttttttaaaa gctgaagaaa aatgatggat cgaatgaaat cctaatatat
     2401 ctgcaatttc tgtataggtt aattcatttt ctagcacgag acgttttgct ttttccattt
     2461 ttagttcttt aaaatagcta ataacacttt ttccattcac ttttctaaaa tgttttttta
     2521 agctggctgg actgataaaa aaaatttggg ctaattgttc aagcaaaaaa ttttctgaaa
     2581 gatgttcttc taaatatcgt atgattggat caactaattc atctgaataa agaatatgct
     2641 tttttttagg aatgactttc tcatttgaag gtattgtcaa taaagcaagt tcctgttgat
     2701 aatgccttgg taaggaagac aattgaattt tttgcagaca ataagtaact aataaggaaa
     2761 gcaaatgaat gctcatctgt tggcatagta tgaaaaaaga attgatttcc tgatcatagg
     2821 aaatagctgg cttactatgt tttagataat caattttgaa ctgttcattt ttcagaaaag
     2881 taatgataga tgttatttct tgatctatag aaaaagattg tcccgtaata tgtgctaata
     2941 attgctcatc aaaataaaac tggataatga taaaagtttg tgtttccttt tgagtagaaa
     3001 agatttggac ttcttgctgt ttatcaatga ataaaaggga aggattatct agttctatag
     3061 atttatgtgc aaattcagca tataaattag cgctttcatt tattagtagt cgaaaatagg
     3121 gagcagcaga taaatgaaga tgggtatcta tggaataggt tagtgttttt ttgacaagat
     3181 tggaggattg gttgtttgtt aacaaaagaa ccactttcct ttctcttttt atataaaaag
     3241 ctttctattt ataattaatg actattataa caaaaatgaa aagccaaaac gacaagtaaa
     3301 atattttttt atataaatat ttgtgttact aattccgtta atatacataa gtgaaagcgt
     3361 tttatataag aacttgaaaa gaaagaaggg atagacatga aaaaaagata caaattggtg
     3421 atagctttgc taaacattac cctattattc agcttaagtg catgtggaaa aactaacgaa
     3481 gaagtaacag caaacatcgc agatccaatg ataaaaaaag ccactacatt agaagtatat
     3541 gtcgcaaacg gcaaactgac aaactatgtt gaaaatgctg caaaaatcta taaccgcaaa
     3601 actggagcaa atattgactt aaaaattgtg aatgtagctt cgggaacagc aacagtacaa
     3661 atgatcaccc caaaattggt aacacacgaa gatatgccgg atattatctc catggcagac
     3721 acttcagcag caggtgtgct ggaaaaattt caagatgctt tttatagtgc tgatgaatat
     3781 ggattttatg acaaatatgg cgatcagttt tatgatcaaa aattgaatat tttgcgtcaa
     3841 caaacgagta atgaaacgat tattccttgg gctagtgatt ttaccccagc actttgttat
     3901 tatcaaccaa aaaaatttgc tgaaataggt gtagattttg aagaaatcag ttcttgggaa
     3961 gaatatatcc aggtggcaaa agcattaaaa gaaaaaactg gtagttttgg aattgccttg
     4021 ccagaatctg gggaccaaga attgtttatc aacatgctag cccagcagaa tcaatctttg
     4081 cttgatgaag aaggaaatat ccgtctgaat actaaagaag cgaaacatgc tgcaaagtta
     4141 atcaaagaaa tgatcgactc agatattgta catttctacg gtgcacaaga tgctgagaaa
     4201 gcatttcaag aatctgcaat gtttgttgct ggcggctggt atgctacgaa tatgtctttg
     4261 aattttcctg atgcatctga caaatggcgc atggctccac tgattccttt ttcaaaagaa
     4321 aatccaggaa aaggtgcagt atcaggagga tcaagttttt atgtccctaa agatgcaaaa
     4381 aatccacaag tggcacaaca atttcttaca tttatgctga cagatgaaga atgcttagcc
     4441 aacgcactgg agctgggcgt ggctacatct aactcattgg cctatcaaac agaagcagct
     4501 gagaaaaagt ttgactacta aggaggacaa aaatactatg aactattgaa taaaatcaat
     4561 gaaaatacat caaatactgt tttaccagcc acttattcag atgctacgtc ttatttgact
     4621 accgctgcat ataactattg gcaaacaggt gattttgaaa attcatatct aaaagaagca
     4681 gaaaattttg ctcataagta cggcgtaaaa ttaactggtg attaaaaaat attaggagga
     4741 cttaacgatg atgcaatctt cgttaccaag caagacaata aagaacagca agaaaaaagc
     4801 aacagatacg tctcataaaa aaagtgctta tggattggtc acaccttttg ttattttctt
     4861 tattgtgacg attttgattc ccatcattat ctcgtttgct tttagtttta tgaaaattgg
     4921 ctactcattt gaatttgttg gatttgacaa ttatctagct atcttccgag atccattgtt
     4981 tattaaatct tacacgaatg ttttgattat catggcagga tcaattccaa taacgatgct
     5041 attagctatt tactttgctg ttttattgaa ttcagcacag ttaaaaggaa aaggattttt
     5101 tagaactgtc tattatattc caaccattac atcaacggtg gctgtagctt ccgtattcat
     5161 gacttttttc aatccgactg ggttattcaa tggatttttg aatgcgctag gaattaacgg
     5221 tgtacagtgg ttaacaaatc ctttttggat acgaatatca atgatcatca cgatgatttg
     5281 gcttagtgta ggatataaca ctattttatt tttagctggt cttcaaggga tttctaaaga
     5341 gatatacgaa agtgctgaaa tagatggagc atcgaaattt cggcaattct ttttattaac
     5401 gatccccatg ctaaagccaa tcattttaat ggccacagtt ttagccacta tcaatggctt
     5461 gggtaatttc aatatcccaa atatattctt tgggacttcc aatggaccag aaaattcagc
     5521 tttggtcgta ggagtcaatt tatataaaac aagttttgaa atggttgatt ttggaaaagc
     5581 ctctgctatt gcctggacga tggtgtttgt atctgttata ttatcggcta ttcaatttaa
     5641 attcggaggt gataaaaatg actaaacaaa agatacaaag cagaattttt acgtacgtca
     5701 ttattgtgtt tggtgcctta atatttttga tgccatattt atatatgatt gtagcttcaa
     5761 cgcaaagtaa tcaagaaatt ttaagtggcg gaatcaattt caagtttggg gatatgctat
     5821 taaaaaactg gcaagccatc atggcgagat ataattatcc cttgattatt tggaattcga
     5881 ttgttattgc tgtaatcagt acagttttag ctacagccag ttctacaatg gcgggttatg
     5941 cattagcaaa gtatcgtttt atggggaata aactgttgtt caatacagtt atgctatcta
     6001 ggatggtgcc tttttttacc acattgattc ctttatttta cattatgagt cgtttaggat
     6061 tatcgaatac ttatgcaggt gtgatcatcc cttcgattgc cagtacaact tcagtgttta
     6121 tgatgcgaca atatagcagt caatttccta cagcactgat ggaggctgcc agaatcgatg
     6181 gtgccaatga gtgggtgatt tttacgaaaa tcgctgtacc gattttatca cctacgatta
     6241 ttactagtgg tttacttatc tttatgggaa gttggaatca atatctattt ccattagtca
     6301 tgctttcaga taaagataaa tatacggttc ccttaattat caaaaatatg acggtttcta
     6361 gtacaggtga gccaattaat tatggcgcaa ttatgctaat tttagcaact tcagtgatcc
     6421 caatggtctt gatttatgtg tgggcgcagt ctaaatttaa ggagaatgac attggagctg
     6481 caaataagta aaaaaaataa cgaatgttaa ccatctagtt cgttctagga gcaactccac
     6541 attcataaaa attaaaagaa tggcgggata tccatgaatg aacagacgaa ggaatggtca
     6601 agaaaaattt tgaatgtagc ttctgaaaag atagatgcgg aattagacag aatggggaat
     6661 aaaattccat atatttctta caacggaaaa tatacagacg taataaagga cagaggaatc
     6721 gactggtgga ccaatggttt ttggagtggt attttatggc agctctttca caagacaaaa
     6781 cgagaaaagt tcaaagaggc agcaatacaa caagaacaat tattagaatc tgccctgtac
     6841 catttttcag acgttcatca tgatgtaggt tttttattct taccatcggc tattgcacat
     6901 tatcaacagt ctcaaaacaa acatagtcga caactagggt tacatgcagc tacggtactt
     6961 gctggacgct ataatatttc agggaactat ttagtagcat ggaatgacca taaacctggt
     7021 tggatgatta ttgatagtat gatgaattta ccattactgt attgggcttc gagggaaact
     7081 ggtgatccga ggttctctaa aattgctcgg cagcatgcag atacaacagc taagtatcta
     7141 gtgaggaaag atggatcaac cgggcatatc gcagaatttg atgcagaatc agggaaatat
     7201 attcggttac ttggcgggca aggatacaat gagaattctt gttggagcag aggaaatgca
     7261 tgggctttat atggattcgc gttaagttat cgttacacaa aaaatccgta ctatctagct
     7321 atagcagaaa agatagcagt aaattttatt cagaaaatcg aaaaaactgg ttatattcct
     7381 ctcattgatt ttgctgtaaa agattcgaat attgatacca gtgctggagt atgcgctgca
     7441 tgcggtcttc tggaattagc aggatatgtt tcctctgtac gatcaaaaat gtatcatgaa
     7501 gctgctatca atatactcca aaagacagaa aagcactatg caaattggaa tatggatgaa
     7561 gatgggatca ttggaggcgg agcagaagca taccatagag aactgactta taatgtgcca
     7621 ctgatctatt ctgattattt ttttattgaa ggcttacttc gattagaaca gtcggaatta
     7681 gctatttggt agtaaaaaga ggagaaaata caatgaaaca tccagtacca ctattaagga
     7741 ccagacagga ttactttgac ttatttaaaa agataaatca accactccag ccgttttatc
     7801 gagcaagtgg cgcacaaatt gattatatac atcaaggggt aggatatgga aataaaattg
     7861 caggaatgga aggattctct cgggttttat ggggagcggg gcccgcaatt gaccaattag
     7921 atgaacgatg gttgaaatta attctatcag gaataaaagc tggaacagat ccttcccatc
     7981 ccgattattg gggagaaata catgaaagag accagcgtat ggtagaaatg cccgcaatgt
     8041 tattagcgtt atatcatcat gaacaattat tatggaaaaa attagataca ggagaaaaaa
     8101 gccagattat tcattggttc tcgcaaattt ttgaatatga atgtgcagat ggtaattggc
     8161 aattttttaa gataattgtc ggaacaatta tccaaaaatt tggttatcca gttaaagaat
     8221 cagcactgaa agaagcattt gataatatag aaaattgtta tcttcaaaat ggctggtatc
     8281 gagacagttc aagaggtcgc caagattatt ataatccttt tgcatttcat tattatggtt
     8341 tgatttatag cgtactagaa ccagaaaagc ccattagcca gatatataag aaccgagcta
     8401 ttgatttttc tagagactat attcattttt ttgcggaaga tggtgcaaat gtgccttttg
     8461 gtcgaagcat gatttatcgt tttgcagttt caagcttttg gtcagctatg ttgtgggccg
     8521 atcttttgcc ttttaaatta ggtgaaatca aggggttagt caatcggaat ataagatggt
     8581 ggatgcaaaa agaaatattt gatgaaaaag gtatcctgaa tattggttat acctaccctc
     8641 aattgacatt gactgaaccc tataatagta cgttatctcc attatggctg aataagattt
     8701 ttttattgtt ggcgctacct gaagaccatg agtattggac ggctaaagaa atgcctatgc
     8761 ctattcgtga aggaactaaa cttctttcag aagccaattt gctcatacaa catgataatg
     8821 gacatacatt ttttttgaat gcgggacaat tagggccaaa tttccataca ttgaccaatg
     8881 aaaaatattt aaaatttgct tattctagtc aatttggttt ttcgataccg cgagcgaatc
     8941 aattgaaagc agaaatggca atggattcaa tgctagggat tcagcgagcg gacacatata
     9001 tcacgaccag ttttaagaat gagagcatca aaacctatgg acagttcatc gttcgaaata
     9061 atgtacgaga cattgtatgt aagaaagagg tacttgcctc tacatgggaa cctactttac
     9121 aggcaaaaat cagaacttgg cttattcctt ttgaaggctg gcagattcgc gtacacaaag
     9181 tagaattaga tacagaatat gttctatatg agacagggtt tgctattgaa tgttctcctg
     9241 agaaagaagg aataatcata gaagaagaca aggaaaacta tagggtgagt gaagctggct
     9301 tttcaggtat tatctgttta agtgacgata ctattaaacg aaaatccaca gctattatgg
     9361 gtttgcccaa tacaaacttg atgacatggg aaaacacttt tattcctgga ttagagggta
     9421 catttggaaa aggaacccat tggctcggaa caggagtggt tgctcatcaa gatcgggatt
     9481 atagtttaga agtatggaac aatcgtccca aaattgattt tgatgggaca accgggctaa
     9541 ctatccaaaa taaaaacaat aaaaaaagac taaaattatg ctaaaggctg gtggggaaat
     9601 gcttgataaa gtgatgtttg aagagataat acatccagaa aaatggataa atgaatgtta
     9661 taaagaatta atggaaaaag aatggaataa tgagatcgag cgttgtcgca gacacacgga
     9721 gaggttaatc aaacgtatca gtaacagtca gtatcaattc ccaagcgagt gtcctataaa
     9781 aggacgttat ccattaagag acaatattgg ttggacagaa ggattttgga caggaattaa
     9841 ttggttgtta tttgagaaga cgggtgatcc tttatttcaa caaacagctg aaaaagcaga
     9901 tatagatttt atccacagga ttgactgtca aattatcact aatcatcacg atcttggttt
     9961 tttgtattct ttatcaaccg tagcagatta taaaataacg ggaaatcgaa aaatgaagga
    10021 agcttcaatt gatgctgcag aaacattact tcagcgtttt tgggagaagg caggagttat
    10081 acaagcttgg ggagatccta gtgatccttc acaacaaggt agaatgatca tggattgttg
    10141 catgaatctt ccattattgt attgggcgag tgaagaaact ggaaatcaaa aatataaaaa
    10201 agctgctcag gctcatattc aaaatgcagc agattattta gtaagagaag atggttcaac
    10261 ttatcataca ttttatatgg atgtcaaaga tggaaaacca agatatggaa gtacgcatca
    10321 aggttatagt gataattcct gttgggctag aggccaagca tgggggattt acggttttgc
    10381 attaagttat cgttatttga aagaacaaaa atattttgat ttaagcaaaa tattagccaa
    10441 ttattttatg aatcggttgc cagaagatac catttgttat tgggatttga tctttgatga
    10501 ttctagcaga gaagaaaaag atacatctag tatggtgatc atggtttgtg gattattaga
    10561 attaatagaa tcaggtctat tagacaaaac agaaaagaac ttataccagt ctgctgtttg
    10621 gaaaattatg cgacaattga aagaaagata tgctacaacg gaagaagaag atggcttttt
    10681 aacacagtct gtttataata agcccaaaaa taatggggta aatacacctt gtatttgggg
    10741 tgattactat tatttagaag ctttagtgag aatgactagt aattggtctt cttattggtg
    10801 aaaaaggtaa atatggaatt tttgtttgat aaaataaaaa aagaaaaacc aaaacagcat
    10861 gaatggtttc tgttttggtt ttttcgttaa ttttcatatt cttctaattc caagcttagt
    10921 tcttcccatt ccgtcaattt tgtttcttga tcttgtctag cagcttctaa atcttggttc
    10981 agctcattga gttttacgtg atcttccagg ttttctggcg cgaccatttc ttgttccaac
    11041 tgatcgatcc attcatcgat ccgcgccatt tcttcttcaa cctgagtaat ttttcgttga
    11101 aggctacgga taagcttttg ctgttctttg ctttggtaat aatcagattt gttcgtggga
    11161 gcaggagcag attctggctc atcttgtgcc aacaattcgg cgatttcttc ttcttcctgc
    11221 tttttctcta aataataatc atagtctcct agatagactt tgctgccatt ttcagagagt
    11281 tcgacgactt ttgtcgcgat ccgattgatg aaatatcggt catgggaaac aaaaagcagt
    11341 gtgccgtcat aatcgatcaa tgcattttct aatacttctt tgttgtcaat atctaaatgg
    11401 tttgttggtt catccaaaat caaaaaattt tctttgttca tcgctaactt ggctaaagca
    11461 acccgtgctt tttcaccgcc acttagcaga gggattggtt tttctacatc ttcgccagaa
    11521 aataagaaag cacctaaagc acttcggatc tctttttctg gagtggtagg atgctcatcc
    11581 cacaattctg ctaggatcgt cttgtttgta tgcagatcag cttgaccttg atcgtaatag
    11641 ccgatggtga catttgtccc tagcgtttct tttccacgga taaaagggat ctggtgaatg
    11701 attgatttca gcaacgtcga tttcccgata ccattcggac ctactagagc aatcgcttct
    11761 tgacgacgga tatctagatt gattggttca gataaggtga cattatcata tccgatagcg
    11821 gcatcttcga tttgcaagac tacatttcca gaaggctttt ctatactgaa tagaaagttt
    11881 gcttgttttt catccccttg aggacgatcc agccggtcca ttttttctaa tgtctttctg
    11941 cggctttgcg ctcgttttgt ggtagaggcg cgaacaaggt tccgagcaac gaagtcttct
    12001 aatttatgga tttctgtttg ctgcttttca taagccttcc attcacttgc taactgttct
    12061 gctttcaaat ctagatattt cgaatagtta cctttgtaat ggcgcatttt tcttctgctt
    12121 aattcataga cttcattgac tactttatct aaaaaataac ggtcatggga aacaatcaat
    12181 aatgcaccag tatagctttg cagataattc tcaagccagg aaagtgtctc gatatctaaa
    12241 tggttcgttg gttcatctag aatcaaaatg tcagggtgtt gcaaaagcat gcgagctaaa
    12301 gctaaacgtg tgcgctgtcc gcctgataaa gtatcgattt tctgatcata aaatgaagaa
    12361 tcgaatttaa acccatgcaa tacggaacga atttcatttt cataaccata gccgtttcga
    12421 tctgaaaaat cgtgttgcag ccggtcgtat tcttttaaat aagaactata agcagg
//
LOCUS       DACBYO010000088        12400 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.088, whole genome shotgun sequence.
ACCESSION   DACBYO010000088 DACBYO010000000
VERSION     DACBYO010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.088"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(28..963)
                     /gene="murB"
                     /locus_tag="IVD26_002333"
     CDS             complement(28..963)
                     /gene="murB"
                     /locus_tag="IVD26_002333"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAP6080262.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1036..1956)
                     /locus_tag="IVD26_002334"
     CDS             complement(1036..1956)
                     /locus_tag="IVD26_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6080263.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2069..2821
                     /gene="xth"
                     /locus_tag="IVD26_002335"
     CDS             2069..2821
                     /gene="xth"
                     /locus_tag="IVD26_002335"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAP6080264.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3685..4218
                     /locus_tag="IVD26_002336"
     CDS             3685..4218
                     /locus_tag="IVD26_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAP6080265.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(4708..5232)
                     /locus_tag="IVD26_002337"
     CDS             complement(4708..5232)
                     /locus_tag="IVD26_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6080266.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(5225..5698)
                     /gene="tsaE"
                     /locus_tag="IVD26_002338"
     CDS             complement(5225..5698)
                     /gene="tsaE"
                     /locus_tag="IVD26_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAP6080267.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(5821..6801)
                     /gene="pta"
                     /locus_tag="IVD26_002339"
     CDS             complement(5821..6801)
                     /gene="pta"
                     /locus_tag="IVD26_002339"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAP6080268.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(6954..7634)
                     /locus_tag="IVD26_002340"
     CDS             complement(6954..7634)
                     /locus_tag="IVD26_002340"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP6080269.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            7760..8629
                     /locus_tag="IVD26_002341"
     CDS             7760..8629
                     /locus_tag="IVD26_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6080270.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            8655..9170
                     /locus_tag="IVD26_002342"
     CDS             8655..9170
                     /locus_tag="IVD26_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080271.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(9217..9780)
                     /locus_tag="IVD26_002343"
     CDS             complement(9217..9780)
                     /locus_tag="IVD26_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6080272.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(9835..10014)
                     /locus_tag="IVD26_002344"
     CDS             complement(9835..10014)
                     /locus_tag="IVD26_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080273.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(10091..10600)
                     /locus_tag="IVD26_002345"
     CDS             complement(10091..10600)
                     /locus_tag="IVD26_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080274.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(10696..11076)
                     /locus_tag="IVD26_002346"
     CDS             complement(10696..11076)
                     /locus_tag="IVD26_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP6080275.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            11406..12155
                     /locus_tag="IVD26_002347"
     CDS             11406..12155
                     /locus_tag="IVD26_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAP6080276.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
BASE COUNT         3591 a         2512 c         2203 g         4094 t
ORIGIN      
        1 tttacttatt ttaagttcca ttacttatta attggctaaa cttctgcttg tttctgatat
       61 tgcttgtttt tctccaatga tccgcacttc tgtttctaaa gacacatcaa atttttcttt
      121 gattacttct tggatgtgcg caatcaattc aatataatct gtcgctgtcg catgatcgat
      181 attgacgatg aatccagcat gtttttcaga gacttgtgca ccgccccatt tcaggccttg
      241 caatcctgct tgttggatca gctgacctgt atagtgtcct actgggcgct taaagacact
      301 tccgcatgaa gggtattcta atggctgttt tgattgacgc aattcggtca actcatccat
      361 tcttgctttg attgcttcat aatcccctgt ttgcaaactg aatcgagctt ccaatacgat
      421 agcacgtaat tcttggactt tactgtgacg ataagaaaat accatttcgt cttttgtcaa
      481 agttttcaat gttccatctt caagcaaaag atccacttca gcaaaaacat ctttgatctc
      541 tccgccatac gcacctgcat tcatataaac cgctccaccg acacttcccg ggatgccgca
      601 agcaaattca aatccagtca atgattctgc caaagctgca taagtcgtat caatcagtga
      661 ggcacctgct tccgcaatga ccatcgttcc tttgacatga atctgtttca tttcagtcag
      721 catgatgact acaccgcgaa tcccgccatc ttgaacgatc agattgcttg catttcctaa
      781 taccatccaa ggtatatcat ggattcggca ataatcgatg atttgcttta cttcttcttg
      841 ttttttcggg aatgcaagga catcagctgg tccacctgtt ttcgtaaacg tatagttcat
      901 caatggttca tcaaacaata tagtaatcgt ggctaagctt tcaactattt cttctttatt
      961 cactgaggat tttcctttct tttctcaaac gtcctcatta ttctatcacg cttaatacaa
     1021 tcttgccagt cttgttcaaa gttgatgacg gtagtgatct ttaagcactt cctcacataa
     1081 ttcatgactt cttacaactt ctttttgttt aagcaattct gtttccgatt tacctaaacg
     1141 gatctgagaa aagaaggcct ctaccattgg ctcaaacccg cgtttgacta gcgtgtttgt
     1201 ccagtcgcca aattctttca ctttttttcc atcagcatct tgaatgacaa gctgggtcag
     1261 atcgtttact tcataagtac catttttact tgttacttga tatttttcta tattagcgcc
     1321 acttgctaaa tccatcgtta aaatagccgt ttgattttgt gtttctaatt gtaaaatggc
     1381 atattccaaa aattcctttg tttctcttat ctggtatttt gttctcaaaa tgggttcatc
     1441 taataaatac acagctgtat caataagatg taaaaacaaa tcataaagga cgaactctgt
     1501 cgtttctttt gccgctattc gatttttttg caggtggatc aaccgcttat ctgggatacg
     1561 tttcaattct tctaccatag gagcaaagcg ccggttgaaa ccgatcatca aaattatttg
     1621 gttcttatca gctaattctt gcaattcacg aacttcattt agatggacac tcagtggttt
     1681 gtcaatataa acatggatac cattttctag acattttttg gctaattcat aatgtacttt
     1741 tgttgctgcg tggatcatac atgcttcgat tttttcttct aaaagctcat cgatcgtttc
     1801 atatagatgt tggaacccgt actctttttg aattctttct tttgtttctt tatttcttgt
     1861 tgcaaaataa aaatcaagtg ttccttgttt tttcgcataa gttggtaaat atgctttttc
     1921 tgcgatattc cctacaccga ttacaccaat cttcatctac tttcctcctg gatcatttag
     1981 ttactttcat cttacaccat tttttactaa aatgaggtac aatagtatcg caaaggtaag
     2041 gaaattaatt cgaaggagtg tgcttttatt gaaatttatc tcttggaacg taaacgggct
     2101 tcgtgccatc gtaaataaaa attttttaga agtttttcat gagttagacg ccgatttttt
     2161 ctgtctgcag gaaacgaaac tccaagcagg acaaattgat ttagatcttc caggttatta
     2221 tcaatattgg aattacgcgg aacgaaaagg ctattccggc acagcgattt ttgctaaaaa
     2281 accagcattg aatgccactt acggaatggg tatcgatatc catgatacag aaggccgtct
     2341 gattactttg gaatattccg atttctttct tgtaacctgt tacacgccaa attctcaaag
     2401 cgaattaaaa cgtttagatt accgattaga atgggaagaa gccttttata attatttgga
     2461 aaatctaaaa aaacaaaaac cagtcatcgt gtgtggggat ctaaatgtcg ctcatcaaaa
     2521 gattgatttg aaaaactgga aaacgaatca aaaaaatgct ggattcactc cagaagaaag
     2581 agcggctctt tctcgactgt tggataacgg gtttatcgat acattccgtt atttttatcc
     2641 aacccaggaa ggtgtctact cttggtggaa ctaccgattc aattcaagga aaaacaatgc
     2701 tggttggcgg atcgattact ttttgacgag caaagattta gagccaggac tagctgatgc
     2761 aaagatccat acggacatta tgggcagtga tcattgtcca gtagaattag atttgaaata
     2821 aagaggttgt gaaaaagtcg tttagtttcg agtattaaga aaaattttgt gaaaatggct
     2881 ttccacattt tgcataaatt tggcataata ccgagaaact ggcttttgaa cactgtttat
     2941 cgagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt
     3001 tcctcatatt tttcgtttgg ttgggcttat taccgcagat acaagctttt gaacaccgtt
     3061 tattaagagg ttgtgaaaaa gctgcactgc atcaagtaat aagaacagcc aaacaaaaat
     3121 agttcctcat atttttcgtt tggttgggct tattaccgca gatgcaagct tttgaacacc
     3181 gtttattaag aggttgtgaa aaagctgcac tgcatcaagt aataagaaca gccaaacaaa
     3241 aatagttcct catatttttc gtttggttgg acttattacc gcagatgcaa gcttttgaac
     3301 accgtttatt gagaagttgt gaaatcagcg tcctgacctg agtattagag aaacaaatgg
     3361 caaaatagtt cctcatattt tgctattttt tgagctaata ccgagggtca gctgattgaa
     3421 caccgtttag tggagaagtt gtgaaaaagt cgcctacttt cgagtcgtaa gaaatttttt
     3481 tgaaaatggt tcctcacaac tttgcataaa tttgacttaa taccgagaag tcatgatccc
     3541 catctaactc caaatcacaa ggaatgagtt caaaaactag cttttctcaa caaatattac
     3601 ataaaaaatt ctatgttttt tgttaaattt atttgctttt ttcaaaagta tgttacagta
     3661 atttcccaag gaggttttac agaaatgaat tttgttgcca tggattttga aactgccaat
     3721 catcagcctt atagtgcttg ttctcttgcg ctagtcatgg taaaaaatag ccagatcgtt
     3781 gatgaattct atacattgat acagcctgag actccttttt tctggcgaaa tgtccaaatt
     3841 cacggaatcc atcaagaaga cgtacgcaat gcgccgaaat tcccagaagt ctggcaaact
     3901 atccaaccat attttcaaaa aaatcgttta gtcgttgcac ataatgctgc ttttgataca
     3961 aaggtcttag cgggatgctt agattattat catcttgaac agcctaatta tctttcttta
     4021 tgtacagtga aaagtagccg tcgcctgttt cctgaatttc caaatcatcg attgaacact
     4081 gtgtgcgaaa atttgaacat ccaattagat catcaccatg atgcattgga agatagtcgt
     4141 gcatgtgcgg aaatcctgct ttatcaagaa aaaaaattcg ggacagatcc attgaaaaaa
     4201 cttgtgacta taaagtaaaa gaatacttat gaaacacaca aagaggtcgt gagcctgccg
     4261 tttcactccg agtcacaagg agcaatttca aaaaatagct tctcatgttt attaaatatt
     4321 gtgactggtg accgaggagc tggcaggaga acaccgttta ttggagaggt tgtgaaaaag
     4381 ctgttctgca tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcattt
     4441 ggttggactt attaccgcag atgcaagctt ttggacaccg tttaccaaga ggttgtgaaa
     4501 tcagcgtttt gacctgagta ttagagaaac aaacggcaaa atagttcctc atattttgcc
     4561 gttttttgag ctaataccga aggtcagctg attgaacacc gtttattcaa aaaaaatgga
     4621 ctgcgacacg acttttgtca cagtcccttc gtgtgttttt ctgccttctc aaaaggatga
     4681 cagtttctca ctcttttcct atttcttcta ttcaatcaaa taactcattt tatatacatc
     4741 taaaaattca cctagatctg ttcttgcccc tctaggcatg accgcttcga tttggaagcc
     4801 catttttcgg taaaggtgta cggctctttc attacgaact tgaacgtcaa gctccaatcg
     4861 aaaaagtaca cccatttcct tcgcccaact gatgatttct tctagcataa gagtgcctag
     4921 tcccattccc caatattcct gcagaatact gataccgact tctcccacgt gagacaaacg
     4981 aaattgactg tctgccttga cagatgctgt tccaataatc gtcccttcat agattgcaag
     5041 cagcaataaa ttattattgc tttcgtatat ataatccaac tcttcttcta aggtttctgg
     5101 tggtaacagg agttctgctt catccaaaac taaaaattct gtctccttat taacttgtcc
     5161 catcatcaaa agaatgtctt ttgcatctcc tggcactgct tcccgcaaga tgatcccaac
     5221 ttcttcactc atgattttca gcccattttt ctagaattcg ctgtttgaag gtttcacttt
     5281 gctccccgta tgagattagt ttcacatacc gcttttctaa atctgtatca cttttttcta
     5341 aaatcagttc caaataatcc tccggcagtg cttcttctaa tagatttccc cattcaacaa
     5401 cggaaagccc atcaccttca aaatattcat ctaaccctaa atctgctccg ctagctgcta
     5461 cccgataaat atccatatga tacaacggaa tccgaccttg actatattct ctaataatcg
     5521 tgtatgtcgg acttttgatc atttgcgtta tccctaatcc ttgggcaatt cctttcgtca
     5581 acgttgtttt acccgcacct agatcaccag tcaatatcag attgtcacct ggcattgcgg
     5641 aatgaccaat tgcctctgcg aattgttctg tcattgttaa tcctgatagt tcgatcattt
     5701 ttcatcttct cccgctcttc tttctttttg ccagtatatc gcgtaatgaa gtttttttaa
     5761 agaaaaaatg aactagtcaa gaacagcagc tgctgttttt ggctagttcg cgtgtatttg
     5821 ttaatcaatc aatgtttgtg ctgctgtgat aatcgataat ttatatacat cttcttcatt
     5881 tgctccacga gacaaatcag aaaccggttt gttcaagcct tgtagaattg gtccgattgc
     5941 ttcaaagtta ccgaaacgct gagcaatttt atagccgata tttcctgact gcaattctgg
     6001 aaatacaaag actgttgctt gaccagctac ttctgaatct ggcgctttca gttgtgcaac
     6061 tgaaggaaca taagaagcat caaattgcaa ttcgccgtcg atcatgtatt gtggcgctag
     6121 ttttttagcg attttagttg cttcaactac tttgtctact tctggcgatt tcgctgagcc
     6181 ttttgtcgag aagctcatca ttgctacttt tggttcgata tcgaacaatt ctgctgtttt
     6241 tgcagaatct acggcgattt cagccaattc ttgcgcagtt ggattcacgt tgatcgcaca
     6301 atccgaaaag acatattttt cttgatctct tccacgtacc atgatcatcg ctccgcttgt
     6361 ccgactgatg ccaggctttg ttttgatgat ctgaagtgct gggcgaacag tgtcgccagt
     6421 cgaatggatc gctccagaga ccattccgtc tgcaatcccc atatacgtaa gcatcgtacc
     6481 aaagtaattc acatctttta aaatcttttc tgcttgttct ttggatgcct ttccatttct
     6541 acgttcaaca aaagtatcca ccatttcatc ccacttatcg taattatcag ggctgatgat
     6601 cgtaaagcta gatgttttga ttcctctggc atgcgctgca tttcttattt cttcttcgtt
     6661 ccctactaaa atgggttcca caagttcttc tgctttcaac cgggcagctg cgcctaaaat
     6721 acgagcatca gtagcttccg ggaaaacgat tttgatccca cggcgaacaa ttttaaatct
     6781 taaactatca aacaattcca caagatgacc tccagacgtt tttatatgta ttatcataca
     6841 ctattccaga aaaaaagaac agtttatttt atctgtatca gtcaaaaatg ctggaaaaat
     6901 taagtttttc acatacaaag cgaactgcac tataacagga aagcgctgtt ttattacact
     6961 gtttcaggca gttgccaatc aatcggttct tctcctaacg caaggagcgc atcattcgtt
     7021 ttcgagaagg gtttggaacc aaaaaagcca cgacttgcag ataacggact gggatgtgga
     7081 gatgttatga tgatatggcg actcttatcg atcattttga ttttttcttg tgccggtttt
     7141 ccccacaaga taaacacgat tggtttttcc cgttcattta atttttcaat gatcgtgtct
     7201 gttaatcttt cccaaccttt cccgcgatga gaatacgctt gcccttcccg aacggtaaga
     7261 acggtgttga gtaaaaggac tccctgttta gcccatgaca ctagatttcc atgttgaaca
     7321 ggtgcgattc caagatcatc ataaagctct ttatagatat ttcttaacga tggcgggatc
     7381 tttacgccag gttgcacaga aaaagataag ccatgagctt gattttctcc atgataagga
     7441 tcttgtccta aaatcaccac tttaacttct tcataaggag tcaattccaa tgcttcatag
     7501 atatgataca tatctggatg gatcttttgg gacgcatatt ctttttttaa aaattctctt
     7561 agatgcagat aataatcttt tgaaaattct gaggacaaaa cttcttgcca actgttatga
     7621 atgatttctt tcaaaaactc cacctcctaa taaaaagaat aactcacatt ttcttcaatc
     7681 acaagggaca atcttcaccc tcagcacttg attaatatgg taaactagga acaagaagca
     7741 gaaaggaacg ataatcatta tgatcaaatt aattgcatca gatatggacg gcacattatt
     7801 agatgcccat atgagtgttt ctcctgaaaa tgccgaggcg atacgttttg caaatgatgc
     7861 cggtgttgag ttcatggtcg ctactggtcg aaactatcaa gaagctcgcg cagctttaga
     7921 tgaggtagga atcgattgtg cgatgatcac tttgaacggg gcacaggtat ttgataaaga
     7981 aggaaattca ttgtttaccg tgtcgattcc aaataatcaa gcaatctctg ttttagatat
     8041 tctagatgct aacggtattt actatgaagt agcaaccaac gatggtcttt attctgaaaa
     8101 tcaagcgaaa cgaattgaaa gttttgcttc catggtggct acccatttac ctcaccttac
     8161 gtataaaatg gcgattgcca tggcctcagc taagctggag ttattgcaca tcacatacgt
     8221 ggacagtatt cgtgctattt tggaagaaaa gaatctggaa gttttaaaaa ttatttgttt
     8281 tcatacagaa gggccagctg tattaggtcc agttggaaag cagatttctc ttttaggcga
     8341 tctagccgtt acttcctctg gtcaaaacaa tatcgaagtg aaccataaaa acgctcaaaa
     8401 aggaattgct gttgcccatg tcgctcacga gcgtgggatt tctttagaag aagtcatgac
     8461 gattggcgat aacttcaatg atgtcagcat gctgcaagta gcaggagtca gtttcgcaat
     8521 gggaaatgca gaaatcgaag taaaagatta tgccaaatat acaacggaca caaaccttga
     8581 atctggcgta ggaaaagcca tattgcgcgc gattgcagaa gacttgtagt tttatctaga
     8641 aaagagggat atagatgtca gaatttttca ttcaggaaaa gcagcttgga cgtgcaactc
     8701 ggacaattgt caaaaacgaa aaaggacatt ccctgttttt gatggttggt cgctggggaa
     8761 caaagggcga tgcattgtct ctttatgcca tgaatggcga tctcgttgct cacatcaagc
     8821 agataagcct gacattcggt acgcgttttg agctgtataa agagttcgaa aaggtgggaa
     8881 ccatgcagaa aatattcaat tggcccggtg acttttatta tattcgtaga cttcactgga
     8941 cagtccaagg tgatatctat aatcatcaat atcaaatcca tcatttcaat cagcaaatca
     9001 tgaaaatgga taaagcaaca cttttttcag gagattacta tgtattggat gtctcaaatg
     9061 atgaagatgc tccagtttgt atttgtattg ctgcggtttt agattactgg ctctaccgta
     9121 aagacaaaag tcgcgataag cctgtttctt accgacttaa cttaagttaa aaagatgtac
     9181 ctgaaatgcg gaaatacgca tttcaggtac atctttttag atattctttt gcatatgatc
     9241 ataaagatga ccactgatca tccgctgacc gacaactttg aagtcatggc gttcgtataa
     9301 ttttttagcc tttggatttt tttcatccac acttagaccg atgacggagc gattagcttt
     9361 cttcgccaat ttaggtaatg cttctaataa tcgcgaaccg atgccttgtc ctctaaaatc
     9421 ttctgataca ctgatagagt ccaaatacca ttcgttggga aacgtttctt tatcaatgaa
     9481 caaacgtgta gacgcatcta gctgatattt ctctaagata ggtaccagtg gctgatcgat
     9541 gattgattct tcttcatctg tataaccgta agcaactcct gcaactttac cgtctatttc
     9601 ttctacgata cctcgtgaat aactgtaacg ataatttgga tcagtgattg cttcttctaa
     9661 aatctctaaa gtcttttgtt cccctgtctg cttcaaaaat ggcagttcca tatcttttag
     9721 aatcactaag atcaatgggg cgatttctgg agcatcttct tttctcgcaa aacgaatcat
     9781 agtttcctct ccttttctcc attctaacat gcagaaaaag aaatcgcaaa atcgttattt
     9841 taaaaaatct tcaatctttt cagtaatgaa ataaccatga gtaacgattc ttgccgcttc
     9901 agttcggcaa taagggcaga cgactggcat ttctttatca ttatgttcga ctacattatt
     9961 gacttcttcg tatgcaaatt tttttccgca attagggcat ttcatttttt ccatgttatc
    10021 tcaacttcct ttcatcttta ctctcttagc ttactcttat attgtaaaaa agagaagcaa
    10081 tatccttctt ctatgcagat atccatacct gacggtcctg ttctccatct attaatcgga
    10141 ctttataata aggacgttca tctttgacta gaagtgtcca ctctttcact tttgcttttt
    10201 tcccgtagta gctgactgct tccttcatcg ctgcttgcgg ttgtttgaac tcttccgttt
    10261 tttctatatc aaaaagatgt tctgcggcct tttccgtgtc atttcgtacg gttgttttcc
    10321 cagtggatgg attgactgct atgacttgtc cttcacaaaa aaactggtat tcatatgttg
    10381 cattcgtagg attctccaaa tctttttcaa ctgcaaaatg aatagcagat atgttatgtt
    10441 cttttgtttc gttttttacg attgctgctg cttttttcaa tgagatccga tattcctggt
    10501 cactaatatc atccatgtga aaagcggcat tgagcagtcc cgtcataccg gtaatcccta
    10561 ttacgatgag ggcagcaaca ccaaacatca tttttttcat tcttcattct cctgtttctt
    10621 ttttttaaag aatatcaaga aatgaacgaa tgaaaaatcg aatgaaacga aaaaaaagtg
    10681 acaattttgt tatctttatt cgtgcagttc taatggcaat ccgtctggat caaagaaaaa
    10741 cgtcattttt tttcctgtaa aggtatcttc tctaatcggt tctgattcga tccctaagga
    10801 ctgcaattct gcaattgttt cttcaatatc gtctactttg aaagcaagat gacgcaagcc
    10861 acaagcttct ggatagtttg gtcgttgtgg cgcattagca attccaaaaa tctccaattc
    10921 agcacttcct agtttcagat ctaatttata gtcatctcgt tctttgcggt aattttctct
    10981 gattacttca aatcctaatt tattaacata aaaatcacgt gatttctgat aatctgaaac
    11041 aatgatggct atatgatgga tcgttgtaag gttcatatga gcactcctat tcttcgttta
    11101 agctcggatc tatattaatc tccagttcca ttgtaaatgt gtcagattga aaaaaatagc
    11161 tgtttttcct ttttataaga aaaaaggcaa aaaaaacaga aagtaggtcc tccaagacac
    11221 tcttcctgtt cccaatataa taaatgaaag taagaaatta tattttcaag aaaacaaaca
    11281 gaaaattatc ataacacaaa ttatttataa ttgaaagact agtttttttt caagaaaagc
    11341 atacaataga ttgtgttagt aaatacagaa cacactacat ttagtgtctt aaggagtcct
    11401 catacatgaa gtcatatttt cagtttttag ctcatcagct aaaaggctgg ccgcaacaaa
    11461 attattatct tttctttttc agtcttggct gccaggtcat gactcttgtc aatagtccca
    11521 tcacttggct gtccgttatt acatttatcg gtaccacgct tggtgtattg tgtattttat
    11581 ccatcaatgc ggcaaaatca gtcaacggta ttttaggtat tttgtctgcg atttgtttta
    11641 ttatcgttgg gttttcagca aagaactatt taagtatcgg tgaacagatt gcttatatga
    11701 tcacattgga tatccccgta ttgttaagta aagaatggaa tcataatatg gcttcaaaaa
    11761 tccgaaaatt cactggaaaa agctggttta tcgcaatcat cagtactttc cttgtctatc
    11821 ttgtttcagg attcctgatt ggtcgttata cagatgatcc tcggccgtgg gtagatgcca
    11881 ttgctttttc tattagcttg actgctggta tcatcagttt cttgcgttac aacaaccaat
    11941 attactggtg gttagcttca gggcttgctc aaatggtcct ttggtatatt tcatttacgc
    12001 atggatctgc aagtttggcg atgttcgtga acagctctgt ttacttgctg aatgatgtcc
    12061 ttgcatttac cgtttcacct tggtataacc aaaaagaacg tgaacgtatg caaaaaatgg
    12121 aagaagaata ctacaacgca caacaacacg cataaaaaaa ctgagcgtgg gacaaaagta
    12181 aagaacactt ttgtctcacg ctctaaacac gtataaacgg cggaatcaga agcaactcct
    12241 tcggaaataa gctgaaattc acaaaaattt gaaaagcaat tttcgtgaat ttcttcttat
    12301 ttcttggagt taaacgcttc tgtcccagcc tctatttcct acgattagtc aagtaaaagg
    12361 tgcaagaaaa atagctcgta aacgaaagcg acaaaatcaa
//
LOCUS       DACBYO010000089        12308 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.089, whole genome shotgun sequence.
ACCESSION   DACBYO010000089 DACBYO010000000
VERSION     DACBYO010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.089"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(133..1116)
                     /locus_tag="IVD26_002348"
                     /pseudo
     CDS             complement(133..1116)
                     /locus_tag="IVD26_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1511..2353)
                     /locus_tag="IVD26_002349"
     CDS             complement(1511..2353)
                     /locus_tag="IVD26_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP6080277.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            2678..3094
                     /locus_tag="IVD26_002350"
     CDS             2678..3094
                     /locus_tag="IVD26_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP6080278.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3091..3561
                     /locus_tag="IVD26_002351"
     CDS             3091..3561
                     /locus_tag="IVD26_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6080279.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3575..4348
                     /locus_tag="IVD26_002352"
     CDS             3575..4348
                     /locus_tag="IVD26_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6080280.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4362..5174
                     /locus_tag="IVD26_002353"
     CDS             4362..5174
                     /locus_tag="IVD26_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP6080281.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5228..6193
                     /locus_tag="IVD26_002354"
     CDS             5228..6193
                     /locus_tag="IVD26_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6080282.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6330..9053
                     /locus_tag="IVD26_002355"
     CDS             6330..9053
                     /locus_tag="IVD26_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6080283.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            9066..9698
                     /locus_tag="IVD26_002356"
     CDS             9066..9698
                     /locus_tag="IVD26_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP6080284.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            9903..10130
                     /locus_tag="IVD26_002357"
     CDS             9903..10130
                     /locus_tag="IVD26_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009320234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HAP6080285.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10199..10465
                     /locus_tag="IVD26_002358"
     CDS             10199..10465
                     /locus_tag="IVD26_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP6080286.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10455..10724
                     /locus_tag="IVD26_002359"
     CDS             10455..10724
                     /locus_tag="IVD26_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP6080287.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
     gene            complement(10903..12204)
                     /locus_tag="IVD26_002360"
     CDS             complement(10903..12204)
                     /locus_tag="IVD26_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP6080288.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         4016 a         1996 c         2415 g         3881 t
ORIGIN      
        1 tcgagcacaa cgacgttttg aaggaacttt gagatattct ttaggatatt aaaattaact
       61 agcaccacgg gtaaaataaa tagtttttct atcaagtata ttgaactacg ataaatttgt
      121 tattttgttt tgtttaattt cgttgtactt attggctttg acttcgattt ctttaaatac
      181 tgggtaatcg gtgtccggca aagctagcaa atctgttttt tctgtgttcc atagatcatt
      241 gataatgaca tgtttttcgt aatggattcg ctctcgatcg tgtgacagct ccaccgctaa
      301 tgcctcgttg aaactggcga aatccttcat aatcggtgta gatgaaaaga agttgtaccg
      361 tacatagccg actttgtttt ccatactacc tttctcgttt ccgctacgtg gattgcacac
      421 ctgtgtctca aaaccatagt gcatagaaaa tcggaggaaa ccgtcagtca gcaccgcttg
      481 ttcagtcttt gtttttgtct aagtaacggc cgttgacata ttatcaatcc gtattttccg
      541 aggaacgcca cctgattggc tgaagagttc tttcatgcct tccaacaaac attcttgatt
      601 ctcggcgggg agtacaacgg cgaatcctgc attactaaaa gggaaagtca tcactaatac
      661 cttcacatct ttaaacgctc catcgtgaca aacttccatc gtaccaaaat caagttgcgc
      721 ttctgctggc gggtgttcaa gacgctcaaa gccttggtct tccagtgttt ccaagtagtg
      781 tgtcgctttc caatcttgaa tgaatacaca gactgttcgg taggatcctg gaaagccatc
      841 ggcttttaaa gcagtagtca ttgcttcagc agtcctacgc tttttatttg gcagcttagc
      901 atcttctgaa agccataggg aaacgatgcc tccccacttt tctgtataca tcataccagt
      961 ctttttgcgt gctttaggtt gcggcagcaa atcatcatct gcatattttt tagccgtgcg
     1021 ccaatttaca tctagctcct ttgcaatatg attaatggat ttatcatgat tatttcgtaa
     1081 atttctgata gtattaatat cggtcattgt gagcatacct ttcttacctc cagttacagt
     1141 gtcgagacta taactttaga ggagtttcag gttgcccgca atggcttttt atcttaactt
     1201 aatcgatttg cggagttgtg tagtttttcg ttgcacttgt atgtactttt attctgccat
     1261 aaacagctta atgaatgtcc acttgaaaaa gtgaataaac gaaatagatg actcgattta
     1321 ataaggaagt aaacccacac agaaatatag gtgattttcc ttgaatgacc aagatattga
     1381 aagttagtga aaaaacacaa aaaggtagcc ctattcacag aaggtctgcc ttttgtgtta
     1441 tcgccagcaa acattagagg gggtatttca tatagctttt gtcctctcga cagtcctatc
     1501 agtttctctt ttaacttatc tctaagtgct gtccagtttt aatagcttct agcttgtttc
     1561 ctaactgtgt ttttaatatg ttgaaggctt ttgaacctgt gcagtggcaa gtaaggattt
     1621 tttctactcg tgagtcattc aatttatttc caattttcat tacctcttgc tcaggtagac
     1681 ctaaattatt tatataaggt atgccaatca tatggaagcc accaattagg tattttatgg
     1741 gtttagtcgg aaatgtttca agagcaattt ccatcatatc gataatgcca tgatgactac
     1801 agccagtaaa gacaatcaga ccgtcttctt gctcaattac gaccaataat tcatctgaaa
     1861 aatcatcata aacaaattta tcatccatct ttttgtataa attcttggtg gtcgagtttg
     1921 ctttgcctag ggggatgata tggaagctcg gagcaagttc tgttttcgtt tttattgtat
     1981 gtaaattctc atgcatttta aggatttcat ttttaggaat accaacatac agaaacgtgg
     2041 ttaaaatctt taaataatgg ggtaaagtta caccttcagc tgtataaata ggggcgtttc
     2101 ctgattttaa atatcttaac ccgccggtgt ggtcagaatg accgtgtgaa ataatcactg
     2161 cctccagatc attcaaagtt tcccccattt tagtcgcatt atagactaat tttttattag
     2221 cgccagcatc gaagagatat ttcttccctg agtagttaat taagagagat aacccatgtc
     2281 cacttttaaa gttcaaattt attcttgagt tttcaaataa aaccttgatt tccactataa
     2341 catctccttt cacatgaacg tgtattcata tattgtagca cattaagttc tattttttgt
     2401 tgtaattacc gaaaaaaata ttaatggacg ctttttacgc tttatttcgt atgtggaaga
     2461 aaatttctta ggatgtggcg ggggattggg gcaaagctaa attccaatta cagtgatcat
     2521 ttaattagac acctttaaat acccacactt tcatcaacac tataatttag ggaaagaaaa
     2581 gtgttggcat gatatagaaa aacctttaat taacagcgtt tcctaaaatt ggcacgcatc
     2641 ttgcttatag aaaagcgtaa ggataggagg aatgaaaatg gcaactataa ttcttgccag
     2701 ccatggggaa tttgctcaag gattaaagca aacagcgaca atgattattg gagatagtgt
     2761 accaattcat gccttgtcag catttagaga tgaagatgaa tctattttgg tacaaataaa
     2821 aaaactttta gccacaatag atatagaaga aacctacatt ttaactgata ttctaggtgg
     2881 tagtgtgaat aatgatatgc tcactattat taaagagtat gagggattgc aattaattac
     2941 tggaatgaac ttacctttag ttatttctat tgcaacctat aatggaaaaa ttggggaaag
     3001 tgagctagaa aagcttatta aagagagtca acaatcagtg attgattgta gaaaattatt
     3061 agtagaacaa cttactggag gagatgacct atgattaagt tagtacgtat tgaccatcgt
     3121 ttgttgcacg gacaggtagt attttcttgg agtaaatcat taaatatcaa tcgtattatt
     3181 attgccaata aagaggcagc gaatgatgaa ttcaaaaaaa tgtctttgaa tttatctaaa
     3241 ccgactggca ttaaattaac aattttttca gttgaacagt tactagaaaa aatgcctaaa
     3301 atcgaaacac ttaacgaaaa tatcatgctt atttttggta atacaaaaga aattcgtcaa
     3361 ttttgtgaag cctatcctaa agtacaagaa atcaactatg gagggataat caaaaaagaa
     3421 ggttccaagc aatttagtaa tgccattttc ttgaatgaat ctgagcaaga agatgccaaa
     3481 aaattaaaag ctcttggcat taaacaattt attcaacagg taccaacttc taaaaaagaa
     3541 gatttgaata caatgttata aaggaggaat gaaaatgctc gttcagtcaa ttggtttagg
     3601 gttaatcggt gttttttgta ttttagactc aaggctttta ggaagaatga attttgaacg
     3661 accgttgatt gtcagtacgc ttgttggttt ggtacttgga gacatggaaa aaggattaat
     3721 tgttggagcc tctttggaat tgatgtcctt aggattagta aatatcggag ctgcttcacc
     3781 acctgatatg aatatggcat caattattgc tacagccttt gccattttat caaatgcgaa
     3841 tgcagaagca gcattaacga ttgccattcc aatttcagtg ttaggtcaaa tactaggtat
     3901 cttaatgcgg acgattttgt caaatttgac tcacgttgcg gatcgcttta tcgaacaagg
     3961 aaaatttagc caagcaagga gaattcatat actttatggc tcgggattat atgctctcat
     4021 gtattttatt cctatttttc tagcaattta ttttggaacg aatcttgttt ctcagattgt
     4081 tgatgcgatt cctgagtggc taacaaatgg cttaacggtt gcaagtaaaa ttttaccagc
     4141 atatgggttt gcgttgttat tacaaacgat gttaacgaaa aaaatggtgc catttttatt
     4201 acttggattt ttaattactg cttattctgg attgggaatc attggtattg cagccttcgc
     4261 atgtattgtt gcgtttgtca tggttcaagt tcaaggtaaa aactcaaatg gtaaccaaaa
     4321 tgagccagat ccattagatg acttataagg aggtagatta agtgaaagag aaagatcaaa
     4381 atgcatggaa atatcggcag ttcttatggc gttcatgggc aattcaagcc tcatggaact
     4441 atgaacgaca aatgaacatg ggttttatgt acggaattgc accaattcta gataacattt
     4501 acaagaatcc agaagatgaa gcaatgaaga aagaagctta cgagcggcat atgatgtact
     4561 acaactgtac ccctcaaaca agtgcatttg tgttagggtt aactgcttct atggaggagc
     4621 aatactacga agaccaagaa aactttaatc cggaatcaat cagtgcagtg aagacttctc
     4681 tgatgggacc gctatctggt gttggtgatt ctttctttca aggaacgatt cgggtattag
     4741 cctttggact aggaattaat ttagcccaac aaggtagtat tttaggtcca attctagcaa
     4801 tgttaatttc ctttgtacct tcctttttag ttacttacta tggtgggaaa attggctata
     4861 acatggggaa taaatacttg tctaaactgt atcaagaagg tttgatggat aaagtaatgt
     4921 atgtttgctc cattgtgggg ttgatggtca ttggttcgat gattgccagc atgatcggga
     4981 ttacaacacc aattcaaatg ggtaaagctt ttgtcttaca agatgtatta gatagtatta
     5041 tgccacaatt tttaccatta ggattaacct tcttcatgta ctggttattg cagaaaaagg
     5101 tcaaaacagg atggatgttg gcaatctgtt tagtcggagg aattattttt agtttgttag
     5161 gtatcttaca ataagggaat aaccaataaa tttggttgaa taatataaat aaggaggaat
     5221 tcaattgatg aattcaaaag aaattgttaa agaaatcgta gcgaaaaaag aggtaaaatc
     5281 aatcgtattt gttggctgtg gcgcttcaaa agcggacctt tatcctgcaa agtattttct
     5341 agaccaaaat gcgaagcagt tacggattag tcattacaca gccagcgaat ttaactatgc
     5401 aacaccagca tctgtagatg agtcaactgt cgttatttca gcttctttag gaggtacgac
     5461 tccagaaaca gttgaagcta acgcagtagc taaagaaaaa ggtgctacag ttattagtct
     5521 aacacgaagc attgactcac cgttaacaaa agatgcagat tatgtaattt atcatcgatt
     5581 tgcagagaac tatgctgcta aattagaaaa aacaggctac tgtttagaat tggcagtaga
     5641 acttttacat caagtagaag gttatgacca ttatgaagca atgcaagaag gatttgctac
     5701 tatctatgat cttgcccaaa aaagtgcaga atcagctcgt aaagatgcga agaaatttgc
     5761 tgaacgcttt aaagatgaaa aagttattta tgtaatgagt agtggtgcta cacatgaagt
     5821 agcatactca acatcaattt gcttgatgat ggaaatgcaa tggattaatt ctggtacctt
     5881 ccattcagga gaatttttcc acggaccatt cgaaattgtg gataaagacg taccgtttat
     5941 attattaatg aatgatggaa aaactagaaa tatagatgct cgagcattaa ctttccttga
     6001 acgctttgat acgaaaacag aagttgtaga tgccttggat tatggcttgt cttcacatat
     6061 tgctaaagaa gtcttagact actttaaccc attcgtgatt actgcagtat ttagagttta
     6121 tgcagaagaa ttgtcagaag caagagaaca tccattaact aagagacgtt atatgtggaa
     6181 actaacttat taaaaaatag atcaaactaa ataaggtggc ttgagaaatt aagccacctt
     6241 gttttcttca atgtgatttt atacatatgg taaaataact agtacatatg gtaaaataac
     6301 tagtacatat tgtgaaagca ggtggcaaga tgcagcgatt aaatgactat ctttatcaac
     6361 taacattgct tttgaaatct acgccttcag ataattattc agctcgcagt atttcgcaag
     6421 ctctacagtt gaatagaagt acaatcagta gctacttaaa tgaaggtgtt cgtgaagggc
     6481 ttttcataaa agtaaaaagt tacccggttt tatttttaca tagaacagct cttgaagaac
     6541 tacatatcac actgaataac tccgaaatag aatcaattga aagcttgtta acaatttctc
     6601 aaaaacccgc attagatcaa gtaattggct ctaaaggaag tttgaaagaa gcaattgatc
     6661 aaattaaaac ggcagtctta tatcctggaa aagggttgcc tttattattg atcggcgcta
     6721 gtggatcagg gaaaaccttt ctagcgaata aaatatatga atatgcagta gaagaaaagg
     6781 tcattcacac atcggcacct ttcatagatt ataattgtgc acaatatgtg agcaatccag
     6841 agttactatc ctctgcttta tttggctaca cgaaaggagc atttaccgga gcaagccagg
     6901 agcatactgg tttgctagaa aaagccgatg gaggagtatt gtttttagat gaagtgcatc
     6961 gcttatctga agaagggcaa gagaaattat ttacatttat ggatacgggt gaattctctc
     7021 ctatggggga taatagtatt cggaaaaaag ccgatgttcg attagtcttt gcaacaacag
     7081 aaaatatata tacgactttc ttaccaactt ttcttaggag attgccagtt attgttaatc
     7141 tacctagatt tcaacaacgt ccgtcgtttg aacgtctgtc attgattgat gaattttttg
     7201 tttctgagag ccaaatttta gctaaggaac tatctgtttc tgatgcattg attcatttct
     7261 taatgaatag tgattttgaa ggtaacgtgg ggaatattaa aaatattatc aagtatgctt
     7321 gcggaaacgc atatatccac cagaagagtc agcaaacaat tcaagttaaa ttattggata
     7381 tgcctttaga gtacagttat aaattcaagg agcaactaaa taaacccaga aagaaaagag
     7441 cagatcgaat ctactatcca gaagaaacac gacaagtgca actagaaaga aacaatcagc
     7501 tttttgttca attttttgac caattactta ctggattctc tgaagtgatt gaaaataaca
     7561 aggatattaa actattttta gaagaaatgg ttaccaaggt aacacaagta atggatacgc
     7621 ttatttttca agaggattac gaaaaagagc agtctttata cgccattcta aactatcata
     7681 ttcgtcaaag tattgatttt atgcgagaaa gctacgggtt tgaacaagat ggtaaccggg
     7741 tagtcgcttt ggccaactat ctatatgtca aggataatca agtgattttt gaaaatagtc
     7801 ttcaagaaaa gaaaaccaaa gatcagctta acgaattttt tgctaatgtt cttgaaaccc
     7861 cttattggta tgcaaaaaaa atcttaagcc ttttatctga gtgtttagat caacctgtgt
     7921 atgaagagga cattttcttt attacgctat atttttatag tttgaatgtc acgaatgtta
     7981 aaacaggtat taagagtatt gtgctagctc atggttattc tacagctagt agtatggcga
     8041 atgttgccaa ccgtatgctg aataagaacg tttttcaagc ttatgatatg cctttagata
     8101 ttacattaga gaaaattgaa gcaaaattga ttcaattcct tggagattat cgaacagatt
     8161 caggcttgat tttattggta gatatgggtt cactaaacca actaggcggt ttattagtga
     8221 atcatctaaa tggaccactg ttaatcattg atcatatcaa tacaccgtta ttattggaag
     8281 tcggccaaca agtattaaac aataaaagta tcaccgaaat aggagcagaa attgaaacaa
     8341 gtcttacttt caaaaagcag ttactacttc ccaagaaaaa gaaaaagaaa gccatcatta
     8401 cttgttgtta tacagggatt ggtagtgcga cccagattca ggagatttta acgaaatgct
     8461 tgaaagatgc agttagagaa ttagtaatta ttccgtatga ttacaaaaag ctgttagaaa
     8521 acaagaattt tgagactcct tttcaattat acgatgtcat catgattgta ggtacagaag
     8581 atcccaaaat taatcagatt ccatatattg gattagatcg cctgattaat gggggaagca
     8641 ttggcgaatt tgttcattac ttggaaaaag agctgactat tgaagtgaac gatttacaaa
     8701 aagaattaat tttcaatttt tcaattagta aaattgtcga aaatttaacc attttggatc
     8761 cagataaggt gctatctttt gtacaaaaag caattaaaga attatcgaag ttattaaatt
     8821 ttgatttttc taataatcag ctgtttttgt tgtaccttca ctgtagttgt atgattgaac
     8881 gaattgtacg taaagaaagt gtggatgagc aagaggacat tgaagaatat atgcaagcaa
     8941 atggagaaat aatggataaa attcatagcg ctttttttga gattgaaagg gaatacacaa
     9001 ttgaaatacc agatttagag ttgcgattat tgagcgatat tgttcaagga taggagtgaa
     9061 ttcgaatgac aatgggagta atttttgata tggatggggt actcatagat agcgagacat
     9121 tttattttga gagaagaatg aacttctttc aagaactgga gatagatcca ggatcaaacc
     9181 agattgatga ttatgtgggg aaaacagaag ctgcaatatg ggaaacatta gttcctgagg
     9241 acaaatcatt aagagaggaa ctttatccga aatatgtaga ttatcgaaaa acgcatccaa
     9301 ttgatttcgc taaagcttta cgaaaagaag tgaaaccgtt acttgacttc ctcaagaagc
     9361 gggatatacc attggcactg gcatcttctt ctccagctgt cgagatagag agtatgctca
     9421 ttcaatgtga acttactgaa tatttttcct ttgttataag tggtgagtca ttaaaacaaa
     9481 gcaaaccaca tcccgaaata tatttaaaag cgaaacagca attagactgt gacttcttta
     9541 ttgcagtaga ggattcaacg attggtatta aatcagcaaa ggcagcaaat atctatacgg
     9601 cggcactaaa acaaccaatg caaatcgatc agagtgaagc agacatacaa attgaaagtc
     9661 tacaagaact ggaacaaatt gttttagaaa aaggttagtg aattaatgga aataaggcta
     9721 tatatctgtg ctagctattt tgactaacca aaaaaacttg ctataattca ggtgtagtaa
     9781 aaggtgctgg taacaccttt tacgaaaatg cttcggcagt gataatggga ttggcttttt
     9841 aagtttttta ttttgttcgc aatccctaag gtcatgtgaa tgatcctagg gattgctaga
     9901 atattttgca acagaaccaa aatacgaata gttatcaagc agccatattg actgcggtca
     9961 atttaggagg ggatactgat actactgctg ccgtaactgg tgctcttgcg ggtattcttt
    10021 acgggggtga agtgatccct gaaaattgga gaaaatcgct tcaaaatgac cagcttctta
    10081 aaacgatcag tcagagattt tgcgataccg tgctatctca aagaatttga ataatggata
    10141 tgatgcaaat cttgtttgta ctaacgttgt attgacaaaa aggattttat ttagtacaat
    10201 gttagtacaa atgatgaacg gaggtagaat catgtctcaa tcaaccatta catttaggat
    10261 tcccgacgat gaaaaagaac tggtattaga atatgcaaaa gcacacaatt cttcattgac
    10321 cgaactttat cgaaatgctg tactggataa aatcgaagat gaaatcgatc tacggacttt
    10381 acggagtgca attgaagttt ccaaagagaa aaaagagagt ggtatttctc aagaggaaat
    10441 ggagaaactg ctaaatgaat tataaagtca tctacatgcc gcaagcccag aagcaattaa
    10501 aaaaaatgga cagaaaccaa gctaaaataa ttgtcgcctg gatcagaaag aatttagaaa
    10561 acacgactga cccgcgtcag cacggaaaag gtttgactgg aaataagagt ggggaatggc
    10621 gctatcgaat tggaaactat cgaatattgg ctaatatttg tgattctgaa attgaaatcc
    10681 agatattctc aattggacat agaagtacaa tatataaaag ataaccgttt ttggaacgaa
    10741 gtagagtttc gaaagtcaat gtataatctt ttgaattttg cataatacca caggtagaaa
    10801 ctacccgata ctatcggttg gtttctgctt ttttatggct ctttgtcaaa taggactgat
    10861 agagtgagat aagaacatct aaggtagaat tccttttcta ctttagatgt tttttgattc
    10921 ataggtaatc agattattta gtaagaaaat tctggtcttc attttccgaa agcttcgaaa
    10981 gccataagcg actcgtttca atgctttgat gtgggtatgc agattttcta ttttggcatt
    11041 tgaataaggc aattcgaggg ctaaacgaat gccggattca tagtttataa aagctttttt
    11101 tatagaatgc agttcttttg gaacggaatt gggcatcgtt cttacaagtt taaagaaagt
    11161 gtccgcctct ttgtcgtgaa acgcttgaag aatttcttga tagtaaaaat aggcgattcg
    11221 taattcgtca gagatcgaaa gcagacgatc caccacttca ctttcggtga gatacgccca
    11281 accaaaattg cgccatttgg tccatttgtc ataaacaagc ttgtcctgtc gtttgatcag
    11341 aagccgagac aacgccttta attgtcgata atatttggct tgtgttggat cgtttcgatc
    11401 aaagcttttc atgattcgta cgcgaatatc ctcaaattta cgaatgagat gtttgacaat
    11461 gtgaaaacga tccacaacga gttttgcctt tggaaaacat tcctttatca gagaggcata
    11521 agaaacattc atgtccgtca cgatgacctt taccttcaat cgtgcgcgtc gttcaaattg
    11581 cataaaataa gaaacgagag cctttttctt ccgtgaagga agaatatcca gtaattttcc
    11641 agtatcgcca tccatacaag aaaaggagta gggaccgact tgatttttca gtgaacgaaa
    11701 ttcatccatt aataaacaac gcggtaacca atttcttttt acttttgtca tggggatcag
    11761 agaagcgagt gtccgagaaa cggtcgacca agaaacgccg caatgcttag caattgtcgt
    11821 cattgcttgt ttttcagtta gctcttctaa aattttatag cgcacttgtt tagcgataaa
    11881 gcagtttcta tcgacaatgt aggtattcgc cgtaaaatag gtgtggcagc cacgacagtg
    11941 gtagcgttgt ttcgctaaag caagataagt cagttggttc gcacatttat taagttgaat
    12001 gagcgatttt ttctttccgt tcttaacgat catgccttca tgattcatct gtttacacaa
    12061 aggacagcga cgaatttctt tacttaacgt cgcagaaaca acaagactct tgatattctt
    12121 aatgctcttc gattccacat ttgtgatgaa aatgttttta tctttgattc caagtagtag
    12181 tttgatatga tgaagatcag gcatacagaa cgctcctttg attgtgttgt ggtgattcaa
    12241 ttctaacgga gcttctgtat gttttgtttt ttcatgctca aaagggaccg atagaatgat
    12301 tttctatc
//
LOCUS       DACBYO010000090        12161 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.090, whole genome shotgun sequence.
ACCESSION   DACBYO010000090 DACBYO010000000
VERSION     DACBYO010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12161
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.090"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            333..947
                     /gene="gmk"
                     /locus_tag="IVD26_002361"
     CDS             333..947
                     /gene="gmk"
                     /locus_tag="IVD26_002361"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAP6080289.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            952..1257
                     /locus_tag="IVD26_002362"
     CDS             952..1257
                     /locus_tag="IVD26_002362"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP6080290.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            1510..3918
                     /gene="priA"
                     /locus_tag="IVD26_002363"
     CDS             1510..3918
                     /gene="priA"
                     /locus_tag="IVD26_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAP6080291.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            3933..4424
                     /gene="def"
                     /locus_tag="IVD26_002364"
     CDS             3933..4424
                     /gene="def"
                     /locus_tag="IVD26_002364"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP6080292.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            4417..5355
                     /locus_tag="IVD26_002365"
     CDS             4417..5355
                     /locus_tag="IVD26_002365"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAP6080293.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            5355..6713
                     /gene="rsmB"
                     /locus_tag="IVD26_002366"
     CDS             5355..6713
                     /gene="rsmB"
                     /locus_tag="IVD26_002366"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAP6080294.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            6726..7466
                     /locus_tag="IVD26_002367"
     CDS             6726..7466
                     /locus_tag="IVD26_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAP6080295.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            7463..9532
                     /gene="pknB"
                     /locus_tag="IVD26_002368"
     CDS             7463..9532
                     /gene="pknB"
                     /locus_tag="IVD26_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAP6080296.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            9697..10596
                     /gene="rsgA"
                     /locus_tag="IVD26_002369"
     CDS             9697..10596
                     /gene="rsgA"
                     /locus_tag="IVD26_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAP6080297.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            10609..11259
                     /locus_tag="IVD26_002370"
     CDS             10609..11259
                     /locus_tag="IVD26_002370"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAP6080298.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            11260..11898
                     /locus_tag="IVD26_002371"
     CDS             11260..11898
                     /locus_tag="IVD26_002371"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAP6080299.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            12053..>12161
                     /locus_tag="IVD26_002372"
     CDS             12053..>12161
                     /locus_tag="IVD26_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAP6080300.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGK"
BASE COUNT         4061 a         2266 c         2685 g         3149 t
ORIGIN      
        1 gtattaagcc aaatttatgc aaaaatgtga gaaactattt tcacaaaatt tttcttcata
       61 ctcgaaacta atcggcttct tcacgacctc ttatacacgg cgttcaaaag cttgcatctg
      121 cgataataac cccaaccaaa cgaaaaacat gagaagctgt ttatgtttgg ctgttcttat
      181 tacttgatgc aggacagctt ttttacgacc tcttggtaca gggtagcttt tttaccaatt
      241 tctagctata attaaagata accttgaaag ttgcagaaaa aaagtgcaaa ataaacgata
      301 agtacaaaaa gactagttga aaggacgtcg tcatgtcaga gcgtggatta ttaatcgtgt
      361 tgtctggtcc atccggtgta ggaaaaggca cagtacgaaa agcaattttt gagagtgagg
      421 ataatgattt tcagtattcg atctcaatga ctacccgtaa aatgcgtgaa ggggaggtcg
      481 aaggcgttga ttatttcttc cgaagcaaag aagagtttga atcaatgatc gaagctggag
      541 agatgctgga atacgcagaa tatgtcggga attattatgg aactcctttg tcatatatca
      601 acaagacatt ggatgaagga aaagatgttt tcttggagat tgaagtccaa ggagcaaaac
      661 aagtcaaaga aaaagtgccc gatggtgtat tcatcttttt gactccgcca gatttagcgg
      721 aattaaaatc acggatcgta ggccgaggaa cagatgcaga tgaagtaatc gaagaacgaa
      781 tgaaagttgc aaaagaagaa atcgaaatga tggctcttta cgactatgct gttgtaaatg
      841 atgaagtgcc gctagcagtt gaacgaatca aaaacattat tgccagtgaa cattttcgag
      901 tagatcgcgt aatcggtaaa tatattaaaa tgttaaagga gatgtagtct tatgatgtta
      961 aaaccttcaa ttgactcact attagatcgt gtaaattcaa aatattctct agtgatttta
     1021 gcaagtaaac gcgcgcatga attggatgca agtgcacagc ctactctaga ttcttttgat
     1081 tcagtaaaaa gcgtcggtca agctttagaa gaaatcgatg caggaaatgt agtcaatgat
     1141 ccacatcctg aattaaaacg tgaacgtttg aagatggaag aagaggaacg tcaagcacaa
     1201 aaagagcgtg aacaacacga attggaatca cgtatccgtg aagagcaaaa aatgtaataa
     1261 agaaaaatag agcgaacatc taaaaagaaa agcaaaccca gctgtttcct tttcaaacat
     1321 tcgccactta ttgtctggta gaaaaggctg tgtctgaact ttttgacaca gttctttttt
     1381 ttcttatctg ctgttaattt tttgttagga tttggcagaa gataagacaa atccatcgat
     1441 ctctagtaaa ataggcaagg aactttttgt cgcttgataa gaaaagacaa aaaaaggagg
     1501 aaacgaacca tgacattaac agctgaagtc attgtggacg tacctactat gcagaccgat
     1561 cagccattca cttatttggt tccctctgaa atggaaacag ctttgcaagt cgggatgcga
     1621 gtagaagtcc cttttggtaa tggcaatcgt catgtccaag gatttgttat ggctatccaa
     1681 aaatcagaag aatcagctaa tccatctttg aaggcagtta ttcgtttgct agaccttgct
     1741 ccggtggtca atgaagaatt actttcatta gctgattata tgaaaaaaat tacttacgca
     1801 ttcaaaatca cttgtctaca aacgatgctt ccgagtgtga tgaaagcaga atatgataaa
     1861 ttgatctatc ctttggcaga cacaccagaa gttcaggtat tgtttgatca gcgagaagtg
     1921 atttcctgga aggaagcaga agaagaaggc agcctttctc aattgattcg ctggcgccaa
     1981 gagcaattag tagatatcaa atatgaagtc catacacgaa ataaagtaaa aacgattcgt
     2041 ttggtccgtt ctttgttaac tgaaaagcaa atcgaagaag aatgggcaaa attacggcaa
     2101 aatgccaaga aacaaaaaga acttcttttg tgtttatctg aactgagcca agaagaacca
     2161 attgcttatt tcaaaaataa aggaatcagt actgctgtct tgaatcaagg aaaagaaaag
     2221 ggctggctgg agtttataga atcagaacgt tatcgcgacc cttataaaga ccgagtattt
     2281 gaccaaacga cggcattgga actgaatgca gaacaaaaaa atgctgtcga acaaatcatc
     2341 acagcaggtc agcagcaaaa agatcaggtc tttttgctgg agggaatcac tggcagcggg
     2401 aaaacagaag tatatcttca ggcaatcgct gatgttttgt cagaaaataa aacggctatt
     2461 atgttagtgc ctgaaatcgc attgactccg caaatggtcg agcgattcaa aggacgcttc
     2521 ggagaatcag ttgcggtctt acatagcgga ctttcccaag gtgaaaaata tgatgaatgg
     2581 cgcaagattg agcgggaaga agcgcaagta gtagtaggcg cacgatctgc tatttttgcc
     2641 ccgctgaaaa atatcgggct gatcattatc gatgaagaac atgaatcaag ttacaaacaa
     2701 gatgagacac cgcgttatca tgcgagagat ctagcaattt ggcgcagtaa atatcatcat
     2761 tgcccaatag ttctaggaag cgcgacgccc tctttagaat caagagcacg agctcaaaaa
     2821 ggcgtttatc agttattgca gttaaaccac cgagccaaag cagctgcaca gcttccagct
     2881 attgagatcg tagatatgcg tgaagagttt cagaatcatc ggacctctac tttttctgct
     2941 aatttgcagg aaaaaataca aaatcgatta gacaaaaaag aacaaactgt cctactgctc
     3001 aatcgtcgag gatattcgtc ttttgtgatg tgtagggact gtggatttgt tcttccatgt
     3061 cctaattgcg atatctctct tacactgcat atggatacac gttcaatgcg ctgccattat
     3121 tgcggacatg aagaacctat tcccaatcgc tgtcctaatt gtggcggcaa taaaatccgc
     3181 tactatggaa caggtactca aaaagtagaa gaggaactcc gagaacttta tccgcaagct
     3241 aggattttgc gtatggatgt agataccact cgaagaaaag gggcacacga acagatttta
     3301 caaaaattcg gtgcaaaaga agcagatata ttattaggga cacaaatgat tgctaaaggt
     3361 ttggactttc cagaagtgac attagttggg gtgttgaatg ctgatacctc cctgaattta
     3421 ccggattttc gttctagtga gcatacattc caattgctta cccaagtttc aggacgagca
     3481 gggcgagcgg aaaaagcagg cgaagtcgtg atccaaacat tcaatcctca acattacgcc
     3541 atagaattag ctaaaaaaca aaattatgag cagttttatc agcaggaaat gcatgtacgg
     3601 catcgtggag gctatcctcc ttattacttt actgtgaaaa taaccgccag ccatcctgaa
     3661 gaacaagtag cggcaaagaa aatctttcag attgccaatc agctaaaaga agtgttaagc
     3721 cctcaaagct tgctattagg gccaacgccc agcatgattt tgagagtgaa aaaccgatat
     3781 tattatcaac taatcatcaa atataaacat gaaccgaatc ttcctcatgt tttggatgaa
     3841 attttgaatg gaagccagaa agaacagcga caaggtcttt ttgtggcaat tgacaacgaa
     3901 ccattaaact ttatttaaga aagggccaaa ttatgcgcta tcctatattg atccacccta
     3961 atgataaatt aaaaagaact gctcagccaa tcgatgtaat cacggacgag acaatcgctt
     4021 tattagacaa tttatatgag acaatgattg cgaatgacgg aatagggatc gctgctcctc
     4081 aagtaggaca aaacaagaga attgctgtga tcgaagtaga tgaaggcgag aaatttgaac
     4141 tgattaaccc agaaatcatc gaagcaaaag gtgaaagcct tgacgtagaa ggttgtctca
     4201 gtattccgca tgtctatgga acggtcaagc gagcagatga agtgaccgtg cgttattatg
     4261 atcgagacgg agaagagata gaagtgacgg cttttggcta tttagcccgt gccttccagc
     4321 atgaaatcga tcacttagac ggtatcttgt tcattgagaa aatgatacag cagatcccgg
     4381 aagaagaact tgaagaatat atggaggaac atcttgatga ctaagctagt atttatgggc
     4441 acacctgctt tttctgtgcc gattcttgaa gggctgatag aatcaggtta cgagatccag
     4501 gcagtggtaa cacagcccga ccgtccagtt gggcggaaac gagtaattac gccgacaccg
     4561 gtaaaagaag cggctctgaa gcacggtatc cgtgtgctgc agccagagaa aatctccggt
     4621 tcgccagaaa tggaagaaat cattgaattg gtgcctgatg tgatcgtcac tgcggcattt
     4681 ggccaattct tgcctgaaaa gttattgcaa gtaccaaaat taggggcaat caatgtccat
     4741 gcttctttac ttcctaaata tcggggaggt gcgcctgttc attatgccat catgaatggg
     4801 gagaaagaaa ctggtgtaac gatcatggaa atgatcaaaa aaatggatgc aggcggaatc
     4861 tatgcgcaag aaagcatacc aatcactaaa caagatgatg tagggacgat gtttgaaaag
     4921 cttagccttt taggaagaaa gctattgcta gaaacattgc ccaatatttt ggatggacaa
     4981 aaaccagtac ctcaagacga gtcagaagca actttttcgc caaacatcac acgggaacaa
     5041 gaagcaatcg attggcataa aactgcagaa gaaattgaca accaagtacg cggaatgcgt
     5101 ccttggccaa ttgcattcac gacctatgag ggcatacgct ggaaattatt atcggttgaa
     5161 gtattggcag aaactacaga caaagcacct ggtacgatca tccggaaaga caaaaaaaat
     5221 ctatggattg cttgcggtaa acagaccgtc ttagccatca atgaattaca gccagctggt
     5281 aaaggaaaac aggccgtaca tgatttcctt aacggaagcg gtcagcaagt tcagattggt
     5341 cagcaggtga aataatgaaa aaaatcccta aaaaaatgaa aaaatcagta cgatatatgg
     5401 cattactgac attagagcga gtgaacaagg gtggcgccta ctcgaatctt ttgttgaatg
     5461 agatgatcaa acaaagcgag ctaaatcaaa aagatgtggg tttatttaca gaattgatct
     5521 atggtacgat tagccatcag cgactattgg aattttacgt tgcaccattg atcgctaaag
     5581 caaaaaaagt ggatgactgg gtcaagacgc ttctttatct ttctgtatac caattagaat
     5641 ttttagataa agtccctgca catgctattt taaacgaggc ggtcgaaatc gcaaaagtaa
     5701 aaggaaatcc tgggacaggg aaatttgtaa atggtgtctt gaggaattat cagcgtcaag
     5761 gagcaccaga tctgcaaggc attgctgatc ctatcgaaag actttctgtc aaaatcagcc
     5821 tgcctctatg gatgacgaaa cgactggtgg atcaaatcgg atacgaagaa actgaaaagc
     5881 tcggtttatc gctatatcag cctagccatg ctagtgcccg agtagataca cgccgacttt
     5941 ccagagatca ggccatcact gttttgcaag aagaagagat cacagctgaa aaaagccaag
     6001 tcagtccata cggtatagta gcgaaaaaag ggcatttagc ttctagctca ttgttccacg
     6061 atggcgtcat gacgatccaa gatgaaagtt cgatgcttgt agcgccgtct atgcaaatcg
     6121 agcctgaaca tcatgtctta gatgcctgtg cagcacccgg aggtaagacg acgcatattg
     6181 cttctttttt agatccgtca tgcggtggag aagtggtcgc tttagatgta cacgaacaca
     6241 aagtcaaact cattgaagat aatgcagcac gtctaggtgt ctcttctgct gtctacgctc
     6301 aaaagatgga tgctagagaa gtcagtaaac agttcgaagc agagcagttt gatcggattt
     6361 tagtagacgc gccttgttca ggtcttgggc tgcttcggcg aaaaccagat attcgttata
     6421 aaaaacagcc ggatgaatta gcgaatttac caaaaatcca attggaaatt ttagaaagct
     6481 gcgcaccaac tttaaagtct tccggtattc tgacttatag cacttgtacg atcttaaaag
     6541 aagaaaacca agacgttgtt tctgctttct tggaaagaca ccctgatttt gagaggattg
     6601 atgttttgac caatcctatg ctacaatcat caatcgaaga gaaaatgttg actttgtatc
     6661 cgcatcagtt ttacacagat ggatttttca tttgttgttt gcgcaaaaag taatgaggtg
     6721 aaaaaatgca gattgaatat caatcagatg taggaagacg acgtaacaca aatcaagact
     6781 atgccagtgt atttaccagc cgttcaggtc tcaagcttgc tgtattagca gacgggatgg
     6841 gtggtcatcg tgccggagac attgccagtc agatggcggt aacgaatcta ggcgaagctt
     6901 gggaaaaaca agaagctgtt gacgatgaaa aaatcgccca atggttcatt caatcgattc
     6961 aagaagaaaa tatgctgatt tatcagcgtg gacaagaaca gccggaatat aacggtatgg
     7021 gaacaacaat cgtagcggcc gctctgtcag atgactggtt cacgattgcc aatgttgggg
     7081 atagcagagc ttatttgatt cgtgaagata aaatcatgca attgacggag gatcattctt
     7141 tagtcaatga actagtcaaa tcaggagaaa tcagcgaaga aatggcagtg aaccatccaa
     7201 ggaaaaatat tttaacacgt tctgtcggca tgcctggaac agtcgaagta gatgtttcta
     7261 ctcatctttg gcaactaaaa gatcgactgc tgttatgttc agatggcttg acgaacatgc
     7321 tgtctgaaga agaaatagga acgatcatca atcaagaagg cccattgtct cataaagtaa
     7381 ctgagctgat tgatcgtgcc aatgaagcag gcggagcgga taatatcacc gttcttctta
     7441 tcgaatataa ggaggacagt gtatgatcga gttgggcaaa aaattaaatg gccgttatca
     7501 aatcactgga aatatcggta gcggtggtat ggcaaatgta tttttggcgc acgatttaat
     7561 cttggatcgt gatgtagcag ttaaagtctt acgatttgac tttcaaaatg accagactgc
     7621 gattcgacga tttcagagag aagctttagc agcaacagaa ctcgttcatc caaacattgt
     7681 tagtgtttac gatgttggtg aagaagacaa catgcagtat ctggtgatgg aatacgtcaa
     7741 aggaatggac ttgaaacgat atatccaaac acattatcct gttccttatg aaacagcagt
     7801 aaatattatg cagcagatcc tttctgctat ttctttagct cataaccatc aaatcatcca
     7861 ccgagatttg aaaccccaaa acgtactgat cgataatgaa ggtgttgtaa aaatcacgga
     7921 tttcgggatt gctatcgctt tatctgaaac atcgatcacg cagacgaata cgatgctggg
     7981 atctgttcat tatctgtccc ctgagcaggc cagaggaagt atggcaacga agcagtcaga
     8041 tatttatgct ttagggatca tcctttatga gatgttgacg ggtagcgtac cgtttgatgg
     8101 tgaatctgct gtaacaattg ctttaaaaca ttttcaagat gatcttccat ctataaaagc
     8161 acttgatcca aatgtgccac aagcactgga aaacgtgatt ttacgggcaa cggctaaaga
     8221 acctgcagac cgttataagt cagccgagga aatgtctgat gatctttcta cagtattatc
     8281 accagctcgt gcaaacgaag aaaaatggca gcctcatgtg atggataatg aaacaaaagt
     8341 tatcacaccc cttacggaag atgcaccaat gcctgattca ttcaaatcta tgcctctgcc
     8401 aaaagacaag ccagaaaacg aaaccttgcc agaggaggaa gaagttctgc ctgatcctaa
     8461 aaagaaagga cagaaaaaat ggtggctgat cctattagct attcttgctg ttttaggaat
     8521 cggaacagct gtattctttg cttctggcgg gcgaggagaa gttgttgttc ctgatgtttc
     8581 tgatctttct gaagcttctg ctagagaaac actcgcaaaa gcgaaattag aagtagcaac
     8641 aaaaacagaa gaaattgcag atgacaaaat cgaagaaggt aatgtagtga agacagaccc
     8701 ggcagcggga acgacagtca agcaaaaacg cgaagtcact ctgtatatta gtagcggcac
     8761 gaaaaaaatc aaattagatg attacagtgg taaaagttat gaagatgccg aagcaagttt
     8821 gaaagaatta gggttttctg ctgacttgat tcaaaaagaa gaggaattca gttcagaggt
     8881 agaaagcgga atgatcattt cgcaatctcc atcagaagat acagaagtcg atcctaaaac
     8941 agacacgatt actttcacag tcagcaaagg accagaaaca gtgactttga gtagtcatgt
     9001 aggagaaaac tacgaaactg ttcgtaattg gcttgttaca caaggattca atatcaataa
     9061 tattagtgct acttatgact atagcgacac tgtaccatca ggttcgatca tcagtcagga
     9121 tccagcctcg ggtgaagttg tagcagaaga aacttacatc aattttgtcg taagccaagg
     9181 aacagagcct aaattgaatg atatctccgg ctatacaaaa agcgaagcac aaagttattt
     9241 agctagtgtc ggtgcagaat atatcgggca tgagacttcc gaatattcaa acacggtgga
     9301 taaagataaa gtgattcgta cagtaccagg ggcaggaacg acaattacca aaggaatggt
     9361 tgtgaacgta atttactcta aaggaccaga tccagcgtct tctagttctg aaaaagactc
     9421 ttcagacagt tctagcagct caagtagctc cagtagcaca agcaactctt caaaagaaga
     9481 atcttccagc tccacaagtt catcagctag cacctcagaa agttcaaaat aagtgctgaa
     9541 taaaatatat cagaagggaa tgcgacattg atttgttgca ttctcttttt tgtgtttcta
     9601 tctcttttga tcaattttca agccatatac tttgagaagt ttgcatggaa taacacctac
     9661 tttcctcttc gtatggtaaa ataaacaaaa acggaggtgg cacttatcaa aggacaaatc
     9721 agaaaagcaa tcagcggttt ttactatgta tacgcaaacg gagagaccta tcaaacaaga
     9781 ggaagaggaa atttccggaa tcggaaaatc acgccgcttg tcggagatca ggtgatcttt
     9841 gagagtgaaa atcaaacaga cggctatctt ctggaaatct tgccgagaaa aaatcaatta
     9901 gttcgcccac cagtcacaaa tgttgatctt ggaatcattg tcacaagtat cgtagagcct
     9961 gcattttctt ataatctact tgaccgcttt ctagttacct tggaatacga gtcgatcgaa
    10021 ccgattattt ttttgacaaa gaccgacttg tcagacgacc cagaaaaaat cgaagagatc
    10081 aagcaaacct atactaaaat aggctatccg gtgattgtac ccaatcatac gggtgatacg
    10141 acagaactga tccgttactt cccagaacgg ctatcggtct ttatgggtca gtctggagca
    10201 ggaaaatcga cgctactgaa tcaaatatca ccggaactga atttagcaac aggagagatt
    10261 tctgatgcac ttggaagagg acggcataca acacgtcatg tggaactgat tcctatctat
    10321 ggcgggttag tagcagatac accaggattt agctcgattg actttttgac aattgaagca
    10381 ggagaactgc cgagacaatt tcctgaattt gtagaagctt ctgtccattg caaatttaga
    10441 gagtgcatgc atgctaaaga acctggctgc gaagtaaaac atagagtaga aacaggtggt
    10501 atcgcacaga cacgttacga caattatttg caattcttac aagaaatcga aaaaagaaaa
    10561 ccaatgtatg caaaaaaaga aggtaaacga aaataggagg aaacaagaat gaagatagca
    10621 ccatccattt tgagtgcaga ttttgccaat ttacaaagag acattgagtt agtggaaaaa
    10681 ggaggcgcag attacatcca cgtagatgta atggatggcc aatttgtccc aaatatcaca
    10741 ttagggccaa atattgttca ggcaatccgt cctgttacta aattaccgtt agacgtccat
    10801 ctgatgatcg ttgatccaga aaactacatt ccagcatttg caaaagctgg agcagatatc
    10861 attactgtcc acgtcgaagc aactcctcat attcatcggg cacttcaaat gacaaaaagc
    10921 ttaggagtta aagctggagt agttatcaat ccaggaacac cagtctccat gatcaaacat
    10981 gttttgcctt tggctgatca agtactagtc atgactgtca atcctgggtt cggcggacaa
    11041 agctttattg aagaaacagt agaaaaaatt acggaactcg ctgatctacg tagagagaac
    11101 aattggactt atgcaatcga agtagatggc ggaatcgttc cagaaacagc aaaaatctgt
    11161 aaagatgcag gggcggatgt cttcgttgca ggatcatata tctatggagc cgaaaatcca
    11221 gtcggacaaa tcgaacgatt aaaagaggca ttagactaaa tgaaaatttt attagctgct
    11281 ggaggtaatc cgcaaaactg gccgcagtct ctgctgtcca aatacgatgc ctatgtcggg
    11341 atagaccgtg gtgcgctgta cctgcttcaa gcaggctacc cagtagatct ggcagtgggc
    11401 gattttgatt cattgtcgaa cgaagagcag aaggaagtat ttgcaaaagc caaagagtat
    11461 acccgttccc ctgcagaaaa agacgataca gatacacagt taggtatctt aaaaacattt
    11521 gaacgttacc cgcaagcgga agtcactttg attggagcta cgggcggaag attggatcat
    11581 cttttagcca atctctggtt aggtatggaa cctcgcttca aaccctttgc ccatcagctt
    11641 attatcagag attgtcaaaa ttatttgtct tattatttgc ctggagagca tatagtaaga
    11701 cagataccag atatgaagta tttagcttat tgctgcttga ctcccgtctc gaatcttaca
    11761 ttaaaaggca gcaagtatgt attggaaaat aaagaagtag aatatccgac atcttatgca
    11821 agtaacgaat ttctttcaga taccgcagaa ttttcttttt cagatggtat gattgcagtt
    11881 attcaaagca aagattgatc cataaacaaa taaaaaaatt tgtctttcag gctaaaaatg
    11941 acagaatcta ttatttgcta aaaaaaagct taagaggagc aacttacctt ttgtttcacg
    12001 gcatttagtg ataaaattga acacaagagt ctaattaatt cgaggtgtct ttgtgaagaa
    12061 gttcaatcct aataaaaata ttattattac cttggttatt gttatcatcg tggtgacgat
    12121 actaagtgtg accgctgcgc agcgagcgaa tgaaggaaag c
//
LOCUS       DACBYO010000091        12144 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.091, whole genome shotgun sequence.
ACCESSION   DACBYO010000091 DACBYO010000000
VERSION     DACBYO010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12144
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.091"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..566
                     /locus_tag="IVD26_002373"
     CDS             <1..566
                     /locus_tag="IVD26_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP6080301.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPASEAAKKDLIDILR"
     gene            967..1572
                     /locus_tag="IVD26_002374"
     CDS             967..1572
                     /locus_tag="IVD26_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HAP6080302.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1588..2160
                     /locus_tag="IVD26_002375"
     CDS             1588..2160
                     /locus_tag="IVD26_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6080303.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2412..2669)
                     /locus_tag="IVD26_002376"
     CDS             complement(2412..2669)
                     /locus_tag="IVD26_002376"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080304.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2795..3610)
                     /locus_tag="IVD26_002377"
     CDS             complement(2795..3610)
                     /locus_tag="IVD26_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080305.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            4127..5452
                     /locus_tag="IVD26_002378"
     CDS             4127..5452
                     /locus_tag="IVD26_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP6080306.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5445..5795
                     /locus_tag="IVD26_002379"
     CDS             5445..5795
                     /locus_tag="IVD26_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080307.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            complement(6866..7141)
                     /locus_tag="IVD26_002380"
     CDS             complement(6866..7141)
                     /locus_tag="IVD26_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HAP6080308.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(7113..8066)
                     /locus_tag="IVD26_002381"
     CDS             complement(7113..8066)
                     /locus_tag="IVD26_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP6080309.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8678..10171
                     /locus_tag="IVD26_002382"
     CDS             8678..10171
                     /locus_tag="IVD26_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAP6080310.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            10306..10602
                     /locus_tag="IVD26_002383"
     CDS             10306..10602
                     /locus_tag="IVD26_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAP6080311.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10703..11554
                     /locus_tag="IVD26_002384"
     CDS             10703..11554
                     /locus_tag="IVD26_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080312.1"
                     /translation="MKSDDWIEHNWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11575..11787
                     /locus_tag="IVD26_002385"
     CDS             11575..11787
                     /locus_tag="IVD26_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080313.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         4172 a         1863 c         2268 g         3841 t
ORIGIN      
        1 attattttaa gtctgaaaag gatacatcgt ctctaacgtt aactttagag gaaggagttg
       61 aacctgacaa ggtgacctct aaagtgataa accaattgaa agaaaaaggt agtttgaaac
      121 atttggggga atatgaagtg ttagatacgg ctatgttaac gaaaggaatt ggtcaaatcc
      181 tcagtacgat cacttatttt ataacagctg tagcaggtat atctttattt atcgcagggg
      241 taggtgtaat gaacatgatg tatatatctg tatctgaacg aacaaaagag atcggtataa
      301 gaagagccct aggagctact cgaaaatcga ttatgctgca gttcctttta gaaggtttga
      361 ttttaactct ttcaggaggg ttaattggct atttattagg aatggctctt gcttatagtg
      421 ttggttcttt gataaaggta aacgtgtcac ttgatctatt tactatttta ctagcggttg
      481 gggtatcttc ggttattgga ctggtctttt ctgtaatgcc cgcttcagag gctgcaaaaa
      541 aagatttaat tgatattctt agataaaatc agaatgacaa gaatatttac gttctagatt
      601 ctaaaataaa acacaaagag accaaccagg caccctattg tttctttgta gtatagagat
      661 attctttggc ttgtaagaga tcaatagagt taggtgaccg gagttcgaaa taaaggaaat
      721 ttttgattgt ataggagaat tctttatccc taatatttag aattttgagt atgccatgtt
      781 gatgttttag attctctata aatatagagg tgtatcaaag gtcaactaga ctgtgcaaaa
      841 tagagacact tgaaaaatct atcgggggtc agaaacttaa tagtttttga cacataaaca
      901 aaatcgcgat ataatggggt tgagagtgtt tcataaactt atgtcataaa gttaaggaga
      961 tttcgcatga ttttagagaa taaattggga ttaaccaatc aagttgagtt ggctaaggtt
     1021 gaagaaaaac tcagtaaaca aaaagcgaaa gaattgtacg attgtggaaa aataaatgaa
     1081 atcgaagttg gtacatttaa aggtttatct gaaattcatg aatttctatt ttcggatatt
     1141 tacgattttg ccggaaaaat ccgatcggtc aatattgcaa aaggaaattt tcgatttgca
     1201 ccagttatgt atttagaaca ttcgttacag catattgatc agatgccaca aacttctttt
     1261 gaagagatta tcaagaaata tgtggagatg aatatcgctc acccatttcg agaaggaaat
     1321 ggccgaagta ctagaatttg gctggatctc attttaaagg aagaattgca aaaagttgta
     1381 gattggaact taatcgataa agcagactat ctttctgcaa tggagcgaag tcccataaac
     1441 gatttggaaa tacgctatct aatttccaat gctctgactg ataaaattga cgatcgcgag
     1501 ttatatatga aaggaatcga tgtcagctat ttctatgaag ggtattctga gtatacgata
     1561 gatgatttgt aaaagtaggt ggaccaaatg acgaaatatg gatatgcacg tgtctcaacc
     1621 gcttctcaaa gtacaaaaga acaaattcaa cagttgcttg agaacggcgt agagaagaag
     1681 aatatttttt cagaaaaatt tacgggtaca aaacgggatc ggccaaaatt caatcagctg
     1741 ttggctggtc tgaagcctgg agatgaaata gttgttacga agcttgatcg atttgctcgt
     1801 aacacgagag aagcattaga gatcattgaa cctttactcg atgataacgt aacgatcaag
     1861 gttttgaatc taggaacgat tgaaaatacg tccatggggc gaatggtgac acggacgttg
     1921 ttgagtgtag cagaaatgga acgtgatatg attgtggaac gtacccaaga aggaaaaatg
     1981 tttgcaagaa agaataatcc taatttcaga gaaggacgtc cgaaagcaac aatcacaccg
     2041 aagaagaggc acgcatatga actgcttact tcaggtaaat cgtataagga agttgaagct
     2101 ataaccggtt tcagtcgcag tacgcttttt agaataaaga agaaaattga agaaagttaa
     2161 aaaagaagtc tcagcgaacc agacaggtaa atacttaatg cgttctagat atgagtctat
     2221 tagcatgttg tgaaatataa tattttttta tttacttgat ttctgctcaa aaaatgtgta
     2281 tggtaactgt aaaaggtaaa gtaattaaag gtatgctagc cacgcttact atattaggat
     2341 accatcatat atttataatg aacgatttgt tcgtctacca aacaacacat atcgttcagc
     2401 gtaagtcacg tttaggaacg tggctttttt agtgttatta tcgataaata atctattgac
     2461 tctattgatt ttatctccat atccctacgg tgttgattgt ctttagatct ttcatttaag
     2521 aaccaaataa ctatcataaa aatcagcact gctgctaata taataaacag cattcctatt
     2581 gtgatattac ctattgattt taccataact acgattaaag taataatggc attcaagtct
     2641 cctttgttct ctatatataa attagccata aatcatcttc ctttcaaatt aagatacttg
     2701 tttgatacca ataaatagta agcgtggcta gcataccttt ttctgtaata gcaagtgttc
     2761 taatagtcca aacttaatga tggaccgatg ctagttatag tacagtaatg ttttctttct
     2821 tatctagatt tttagtaagc tctatcagca aatctaacaa atctgagtcc ttttcagaaa
     2881 ctaaattaaa tctagtgttt acaacaaagt tttcatgttc tatattgttt agattatttg
     2941 cggaaaggag ggcttctaga tcttgacatt caaatctata tgcatcgtca taaatcttac
     3001 tagaaggagt gcttaattcg aaattactta ttttctcatc ttggaccaag ataaatttat
     3061 agatagtatc tttttgtgtt tttcttttaa aaacacaaca gagtgtgtta taaggaacgt
     3121 tataattttc atcagcctca ttttttctcc attcaaacaa atgataaact gcaaccaagt
     3181 tgccatcaat ttcatggaca gtgctctcgg taacatcctt taaagaacta tcaagggcta
     3241 atttatagta actagagaga ggaagtaaaa ttgtcgattt actgagatgg ttatcgtcta
     3301 tacgtgcaat catacctaaa tcaactaagg ttttattcca ggtgtttata gttttagttg
     3361 tcactcctag agactctgct atggtattga ccgaatgcca ggaatccccg ccttcattct
     3421 ttgccttaaa acagtaatac agatataaat taatagcttt gttattcggt aaatattttt
     3481 caagttctgt tggtagaata aagtaagaat ccttaatgtt ttttctgaac tgtctccagt
     3541 ctctgtagtt ttgtttataa agttgtgaaa cggtttttcc acctttagaa agtcctgcta
     3601 tcttaaccaa tcttattgct cctttcttga atctgtcatg atcatacagt attttttact
     3661 tgtagtccag caccttaata tattatccta tgtaattaat ttcgtactag atagtaatta
     3721 ttttttattt aattctctag tcacttacaa ataagttata taaactacga ttaataaatt
     3781 attacaaaaa ctattaagaa aacttctaca tacaactatt acaaaactat taagaaactg
     3841 aatactccta ttttttgttt ttaaggaaag ttttttcttt tttgaatttc ttattttttt
     3901 ctaatataac taagcaaaac tggataatac gacacttatt ttcaaatttt cacaagacta
     3961 atagtaaata tccatttaat aaagtgatac aatgtgttga ttttacaaat caacagaaga
     4021 agtagggaaa taacttacct atgcttcttt ttttgtacat ttaatcgatt cttctttaca
     4081 aaaacgaacg tatgtttgta taatgtggaa gaatggagtg ttatttatga tggattattc
     4141 aaaagagcca gtaaatgatt actttttgat cgatatgaaa agcttttacg caagtgtcga
     4201 atgtatagaa aggaatttag atccattaac gactgaatta gtcgtcatga gtcgagcgga
     4261 taatacagga tcagggttga ttttagcttc ttcaccagct gcaaagaaga agtacggtat
     4321 ttctaatgtc agtcgaccac gagatctacc gcaacctttt cctaaaacgt tacatgtcgt
     4381 tccaccacgc atgaatctct atattaagcg aaatatgcag gtaaacaata ttttcagaag
     4441 gtatgtagca gacgaagatt tattgattta ctcgatcgat gaatcgatct taaaagtgac
     4501 cagatcaatg aatcttttta cgactgaagg aacaagaagt caacggagaa agaagctggc
     4561 tcaaatgatc caggagaata ttaaagaaga gctaggattg cttgctacag taggtgtcgg
     4621 agataatccc ttattagcta aacttgcttt agacaatgaa gcaaaacata atgatggatt
     4681 ccttgctgaa tggacgtatc aaaatgttcc tgataaagta tggaatattc ctgaaatgac
     4741 agacctttgg ggtattggat ctcgaatgaa aaaaagactc aaccaaattg gtatcatgag
     4801 tattaaagac ttagctaatt ggaatccata cactattaag agccatttag gtgtgattgg
     4861 cttacagctg tattttcatg cgaacgggat cgatcgaaca gatatagcga tcccaccaga
     4921 accgacaaag gaaaaatcat atggtaattc acaagtgtta ccacgagatt ataccaggag
     4981 aaatgaaatc gaactggtgg taaaagaaat ggcggaacaa gtagctattc gtatcaggca
     5041 acataactgt aaaacaggtt gtgtccattt atacattggc acgtcgatct tagaaacgag
     5101 accaggtttt tcacaccaga tgaagatccc tataacagat aatacaaagg aattgcagaa
     5161 ttactgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc acgttggaat
     5221 aacctatagc aagcttgtgt acactgattc gcttcagctg gatttattta gtgatccaca
     5281 aaagcaaatt gacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg
     5341 ttttacgtcg attgtacatg cttcttctat gttagaaggc gctcgtagta ttactagaag
     5401 tacattggtt ggtggccatg caggcggcgc aggagggctt aaaaatgatt gattataatg
     5461 atcgtggacg tttaaagtgg gcaggttttt atttatctga tcatactgaa aaaattgatg
     5521 ccgacaatga acaacgagcc aatcaaaatt tggcaaaaga acaaatgacg actgaagagg
     5581 ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatgtatt caaaaagaag
     5641 aacgaaacgc tgaaggatac tatccagaag atattgttag caagatctta ggtagtgatg
     5701 agctggggat ctacgttgga aaaaacaaag ttcactacga cgaaatacgt catatcgaat
     5761 tttaccagga taataaatgg ggtcgattag aatgaacatt atccagcaat atgagctaaa
     5821 gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccagc gtttgataaa
     5881 tgaggttggt gttgaacgct tctctttcta tgtagaagct gcagcaggat accataaata
     5941 cgaatactat attggctatt aaagtgcaat aaaattatat ttcttttatg ttttacattt
     6001 tgtatcaatt ctgataaaat tacctatagg taattaaaaa atataaaaaa actagttaca
     6061 accttaggac gttgtaacta gcttgaagca tactagagct aactaaaata gcactagaaa
     6121 gcaatgttaa acccgtccaa caaacttgat ttaacattga gaccagctta ttcagctaaa
     6181 tatagttgaa taagcttctt ttgttttaaa aaaacaaaag gtgtactacg aataacgcaa
     6241 gtaaaagaaa tactattaca accagtaggc tacaagtaag tattactaaa cattgcgtag
     6301 ttagaacctt tgctctattg tctaaagcca caaaattaga gatcagcttt atgatgctaa
     6361 gagcgagctg catccatgcg gacataggtt cttttgacac tattaattct cctttttagg
     6421 ataagggaaa ttgctagtag ttttttcatt agcaccatcc cccttcattt gattgagtct
     6481 agtgctgctg tgatagtttg ctgtttaata tgcttacatt cttattataa cataaatgaa
     6541 acaaacacat ggttagaggt cgtatcaatc aaaatagtgt ctcacaaacg atttattact
     6601 tactcctgct gactaacgga ctgttcttca gtaactgtaa ctatatgttt gttaaaacca
     6661 ccattacctg tagataaaaa ccaatatatt tactatactc actatattaa atatatttag
     6721 tatagtaaaa actagaaaca ataaaatttg tgaatgttgt atacccccaa acaatacaca
     6781 tattttgaag gattaggatt aataaagcta aaaatatagt aagtatacta aatatattta
     6841 ctatatctag tatacttact atattttaat cttttgatcg tctattatat ataatccgtt
     6901 cctcgtcgtt taaagtatca acataggcgt ccattgcaag tttgactatt tcatacatag
     6961 gaatatcttt tgcataacta agatcccgaa tggtttttag tacgggagga tctacttgaa
     7021 ctggttttct ttctttcgca gtgtactttc gttcccctaa ctcgacatta atatcatctt
     7081 taattgaaat atcttcagca ccaattttct tcttatcttt gttcgttggt aataatgcca
     7141 tttagtttaa tctcctttcc aagaggtagg atatgattgg ccattgagtc agcatattta
     7201 ggtgtataat caaatccttc aatatcacca tgttgttcat agtattcaat tctttcttct
     7261 aattctgtaa agatgtctgc aaaaatagcc caccatcttc gatctacata atcatttaat
     7321 tggataccat tctcaccata catttctaac cgatccgagc ctttaacaat gcttttaaaa
     7381 atgtttgatt caccatactt atcaattgtt ttttgatagt ttgcgtgttg agaggaacgt
     7441 cgcactgaga aaagaacagg caaaattcca atgatttgaa gatgagactc ttcaaaattc
     7501 gtgacaatcg gaactaaaac tttattaata aaatcttctg ttccttccat tgcgtaccgt
     7561 tttaattctt gcattgcaat aatataatct gcagcagtta agaatgcacg aaccacatta
     7621 tctgttgatg gtgggcagtc gataaagata taatcgaaat tttttctcaa ttcttctaaa
     7681 ggtttaatga aggccaatga tctcttacga cgatcaggat atttttcgga caagtattca
     7741 ttaagttctt cagatccagg agagccagcc ataatatata aatgtggact tacttgagta
     7801 atacctgaaa cccagtcccc ttttttgatt gctgcagaca tggatcgatc aaagctagta
     7861 atttgatacg ttgatccaat gttggaagta gtatttcttt gttggtcata atcaattagc
     7921 aacacgtctt tttcaaaaag ttgactagaa acaatcgcta ataaatcatt gtctgtagtc
     7981 ttaccaatgc cgccttttct acctgtaagc attacaactt ttcctagttt atctgatgtt
     8041 ttaaatgcag tccgtaagtt ttccatagtt ccctccaatt tcctatacta aatatattta
     8101 gtatacttca tatacttaat atattcgata tatctaatat actccaaatt gataagaatt
     8161 cagactttat aaggaatata gtggatatac taaatatatt tgctatattc agtatatcag
     8221 atatattcaa aatgtcaaaa tatatttgtg cgttttgcgt tgacaattta gagtgaaaag
     8281 aggtaaactt aattctatag aaaccacaga taattcacta tttacaaagt agcaaaagca
     8341 gtggtactct ttaaacagaa aaattacata aaaaaaagag acggaaataa ttgattttag
     8401 cagaatcaat tatttctgaa tcacatggtt aggacatgtg ttcacgctcg tctcaagaat
     8461 atgtaagtag ctaccaacta cttatattaa aagttgatcg gatacctttt ccgattgcct
     8521 ttattctacc aaaaaaaggc gagcaactca acagaagaac gtttatttag tgtacttaaa
     8581 ttaaatattc ttaaacactg aagagagaac acatactatg gctgagatta aagctaaact
     8641 gtgttctctt tttgtttgag aaaggacgtt acaatcgatg ttgagcgaaa tttattcagc
     8701 tattcttaaa aacggcttac gtacatacaa atatcgaaac agcaccatga aacctgcagg
     8761 tcatattgat tccagtagga gtggtgctat ctttgcgtac cgtagcaagc aattaatgaa
     8821 tgttgggcgt ggtatggtca ttacttcgga agaagctatt ttagagaacg aaaagaaact
     8881 aacgcattgg acacctaata cctatcgctt tggtacttat gcggatgatt atcgaacagt
     8941 ggttaaaggt cattctgaga aaaacttaag tcaaatcaac acatttgtag ttgatatcga
     9001 ttcaaaagag aaccatcaag gcgaaattat tttagcctgt ttagatcaag tgggctacat
     9061 gccaacgcta attttagaat cagatcatgg ttatcaagtt tattttgtac taaagacacc
     9121 aggctatgtc acaaagaaaa gcaatttcaa ggtgatcgat gtagcaaaaa aaatttcaaa
     9181 aacaattcgt ctacagttgg ctgaaaaatt gtccggagtg gatctaggat gtaaccactt
     9241 cggaattgct cgattcccac aagaaaataa tattgttttt aaagaaatga actatcagta
     9301 ttcttttgct gactggattc aatggtcgat gaagcttgaa tcagatcaaa aaacaaaaga
     9361 agatcgagaa cgaaaactaa ttgtctttcc tgagaaaaaa gaaattcgtc aagtagatga
     9421 accgtggttc gatatgttac ttcataaagc aaacatcgtc ggcggagaag gacgtcttgg
     9481 tcgaaataat gtgattttca cgctttcttt agcttattac tcttcaggtt atgcattgga
     9541 tacttgcgaa tacaatatgt tcacattcaa cgaacggtta caggaaccgc tatctgaagc
     9601 agaattagta aagattgtac gtagtgctta ttctggtaat tatcaagcag caagcagaga
     9661 attcattatt gaattgtgcc agcaatgggt ttcaccaacc ttaaaaaata atgatctgtt
     9721 cattcaacga cgtggctggt ggaaatttaa aaagccacga gatcaaagaa aatatagtca
     9781 taaaaatgaa tggaaagaag atctattggc ttatctaagc gaaaaaagtc ttgctagtga
     9841 gccttatttg aacctgtcaa aaaaagaatt ggcttcacaa ctaacgatgc ccaagcgaac
     9901 acttgataag atcttaaatg agttacgaga ggagaataaa gtcttctaca aggtaacacg
     9961 aggaagaaat ggcggaatga tcattgcttc agtcaaaacg ttgttcgcga gggttattca
    10021 actaagtaaa gaaaagagac tagattattc aacaaggatc acagaggtat ttggactcaa
    10081 cgagagctta gtagaagaga catttagaca attatcaacc cccttgaacc ctcttaaaga
    10141 agtgaatctt tttgaagtag atacaggttg aaaaataaaa ggtgcaaatt gccttataca
    10201 atatatctat gatacttctg taggtgttgc tccctttgcc tagctacgtg taggtggtat
    10261 acttataact gcgtatgcag tcttatgtat catggaggaa gttgtatgtc gttaaaaaat
    10321 tatgtctatt cacatcctgt taatgtgttt atcattggtc gtttgggatt atctgtggaa
    10381 gtgttctgtg agctttatgg ttttaagcag gggactttgt cttcttgggt taccagggaa
    10441 aaaacagttg cttctttgcc gattgagttt cttcatgggt tgtccttagc ttctggggag
    10501 actatggatc aggtatatga ttgtttgtgt gtgttagagc aggagtatat tgagtataaa
    10561 atagctaacg agttaagaaa aaggaagaag tatatccagt agtagttttt atttacttaa
    10621 aaaattggtt cattgagcaa cctatcgctg ctaaagtagc aaaggaaaac gttaaaggaa
    10681 agaatttagg gaagaaatcg aaatgaaatc ggacgactgg attgaacaca actggcttcc
    10741 tctgaaaaga aatagcaaac gaaagaaatt ttgggtattg caattatggc cattaggaaa
    10801 actttgtagt tacggggcac gacttattct tgatttaacc gtttactcga ttggagtatt
    10861 tggaacggct tattacttga taaatgatcc caataggatt gcagcatcag acatttttac
    10921 agtgctaatg acgttgattt ttgtcatgct attgtctatt tttactcaat tagtcatgca
    10981 atttaccagg caaaaattaa cagcaggaaa acttttcaaa agcctattcg atttaattgt
    11041 tgtaaatgca attctagcga ctttaataaa acaaattgaa caatctggaa gaacaacaaa
    11101 aggagtgaag gattttttat tgacgtttat tcactttgta aatggacaca tgtatttgtt
    11161 tgaagtgggt attattctct tttttgtcgg gtatgtatcc acgaaactta ttaaacgttc
    11221 aattgaaaaa gaaattgaaa ttgacctgat tccgacactt cttggttatg agtacaatgt
    11281 tgattttgga agatatgacg aattgatcaa tacggatatc gttcacacga gtatccatga
    11341 atctactgtt aagggcatca gatctatttt aaaaaatggc caggaaatga aagcaataga
    11401 tcgaagaaaa gagatctaca atttttatga agtcgaagca agcctacgat atggcatcgg
    11461 aaaattgtgg ttagatggaa gtaatattcg tcaaaacaaa ccatacattt tttggaacag
    11521 tagtgattta gaacttccaa tgaaagataa ataattatgg agaatcgttt gaaaatgatt
    11581 cctctataca ggattgtgct tatagttggc atggagttaa aaaccttaaa gaaggagcag
    11641 ttattcaaag tgaaagaacg tcataatcag ttactatgta gtaaaacggg tacgatgaac
    11701 attgaatacc gaacagaata tttagaatta acgaatcaaa ctgatttttt gttgattcga
    11761 aagcaacaag agcaagaaaa aaattaatgg ctacttatag ccaattgatt gatgaatggg
    11821 aacaattcaa ggaatctaaa attccagaac gtctctaaaa gcctttattt gtaaagagca
    11881 taaggaaacg tgggaacact ttttaaaaaa agtgttccaa taggctgtgc ctattacgtt
    11941 tctcaaaaat aaatgtggga acaaaatatt taaaaatagg atagtgaaag gatagtgaag
    12001 gatagtaaaa ggagggtagt aggatagcaa aaaggatagg ctccttttcg ctatcctttt
    12061 taaattggag gaattaatat ggaagtaaga ataagaaatg tggatgagaa aatcgtaaga
    12121 gaaattgatc gaagatgtga cgaa
//
LOCUS       DACBYO010000092        11748 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.092, whole genome shotgun sequence.
ACCESSION   DACBYO010000092 DACBYO010000000
VERSION     DACBYO010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.092"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..608
                     /locus_tag="IVD26_002386"
     CDS             <1..608
                     /locus_tag="IVD26_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080314.1"
                     /translation="ENQLFAGDVLEIVLNDQAGEAAAKGVQNKPSTNDEIGNHNPSDT
                     PVVYHDAPPFAPATKIVVEGGLSFLAPSKLDCGQIKATGLTQEAFGQMDIQEKLWIYD
                     QRETKSPWILTIKLSQPFTTDAGFSMQDVLYFKKAEEYQLVNEEELEIVRGQNSTNVQ
                     TDYSEYLNNGRAFKLVLTKENQIAGNYSAEMTWTLADAPTE"
     gene            628..1656
                     /locus_tag="IVD26_002387"
     CDS             628..1656
                     /locus_tag="IVD26_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP6080315.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            1653..2411
                     /locus_tag="IVD26_002388"
     CDS             1653..2411
                     /locus_tag="IVD26_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP6080316.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(2497..3237)
                     /locus_tag="IVD26_002389"
     CDS             complement(2497..3237)
                     /locus_tag="IVD26_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6080317.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3298..4551
                     /locus_tag="IVD26_002390"
     CDS             3298..4551
                     /locus_tag="IVD26_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP6080318.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            4852..5100
                     /locus_tag="IVD26_002391"
                     /pseudo
     CDS             4852..5100
                     /locus_tag="IVD26_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5222..5548
                     /locus_tag="IVD26_002392"
     CDS             5222..5548
                     /locus_tag="IVD26_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAP6080319.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            5616..6329
                     /locus_tag="IVD26_002393"
     CDS             5616..6329
                     /locus_tag="IVD26_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP6080320.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            6639..7491
                     /locus_tag="IVD26_002394"
                     /pseudo
     CDS             6639..7491
                     /locus_tag="IVD26_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            7612..9477
                     /locus_tag="IVD26_002395"
     CDS             7612..9477
                     /locus_tag="IVD26_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6080321.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            9525..10934
                     /locus_tag="IVD26_002396"
     CDS             9525..10934
                     /locus_tag="IVD26_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAP6080322.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            11042..11743
                     /locus_tag="IVD26_002397"
     CDS             11042..11743
                     /locus_tag="IVD26_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6080323.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
BASE COUNT         3949 a         1972 c         2471 g         3356 t
ORIGIN      
        1 cagaaaatca actttttgca ggagatgtat tagaaattgt attaaacgac caagcaggag
       61 aagctgctgc taagggtgtg cagaacaagc caagtaccaa cgatgaaatt gggaatcaca
      121 atccaagtga tacgccagtt gtttatcatg atgccccgcc ttttgcacct gctacgaaga
      181 ttgtagtaga aggtggtctc tcatttcttg ccccttccaa actcgattgt ggtcagatca
      241 aagcaactgg gttgacgcaa gaagcatttg gccaaatgga tatacaggaa aaattatgga
      301 tttatgatca gcgagaaaca aaaagtccat ggatcttaac gataaaatta tctcagcctt
      361 tcacaaccga tgcaggattt tctatgcagg atgtcctata tttcaagaaa gctgaggagt
      421 atcaattagt gaatgaagaa gaactggaaa ttgtcagagg acaaaattca acgaatgtgc
      481 aaacagatta ttcagaatat ttaaataatg gtcgggcgtt taaacttgtc ttaaccaaag
      541 aaaatcagat agctggtaat tactcagcag agatgacatg gacattagca gatgcgccga
      601 cagaataaag atcaaggaga atgattgatg aatcgaatat ggaataaaag tcatcgaaac
      661 aactgctctt tacttctgat ccttctcctt ggattcatcc tttggcagac acctgtccat
      721 gcctccgaat tcaattttgc ggtagatttt gaattaccgg ctaatcagat tgataagaac
      781 aaaacatata taaatgtaag gatggagcct gggaaaacac aggaaatccc ctacacggtc
      841 tttaaccgaa cagataaatc agtaacagtt gagacattga tccactccgc tacgacgaat
      901 tcaaacggtg tgatcgaata tggagaatca aaaagtaaat ttgatgaaac attaagttat
      961 gatatgaaaa acttagcaaa aacagtggga gaaataactg tccctcctca aagtgcggtc
     1021 actgagacac tttcactgaa agctccagaa aaagagctgg ctggtgtggt cgcaggagga
     1081 atcacgtttc aagaaaaaaa agagaacgtt tctaacaaaa gtacagttgg tgtcgtcaat
     1141 cagttttctc aagtgaaagc aatcttgatt cgaaatagcg aaaaagagtc ttccccaaat
     1201 ttgaaattaa aaaaaactta tgcggatcaa agcgatggaa gaaatgtgat taaggcgaat
     1261 cttcaaaatc caaatgcttc ttatatgttc ggcttgacta catcggttga aatctacaaa
     1321 aaagaaacaa aagagcctta tctttcaata aaaaaagaaa aaatagatgt agcacccaat
     1381 acaaattttg atttacttgt cccattagaa ggaaaaaaat tagctccggg acattatcaa
     1441 gcggttgtga agggtgcttg gaaagaaaaa cgctggaatc tccataccga ttttgaaata
     1501 actgatgatg cagcggacca attgaatgaa aaggatattg atttaaaaaa tcagccagaa
     1561 acatttgact ggcgatggct gatacttgtt ggagtcattc ttattggctt atttgctgga
     1621 ttatttattt taaaagaaag aaggaaaaag aaatgaaaaa aacaattgca ttaagtaccg
     1681 ttctagctgg aagtctatta ttatgtacac aaagtgtttt tgctgagaat aagagctcag
     1741 ccactacaga aggaacgatt tctgtaacaa aaccagatgc cgcaaatcct gaagacgttg
     1801 ttccagttcc tcctgttgat ccaaatgatc ccgatacgcc gtttacacct aacgaaccaa
     1861 atcagggaac atccggatta ctgacgattg accaagctcc agatcttgat tttggaacaa
     1921 tcaagttagg tacagcaaaa acagtatatg ctgcattaca aaacggaacg gacagtacag
     1981 ggacagcaac acaagtacag aatttcgtac aagtaacgga taaaagcgga atttatgccg
     2041 gttggaaact atcagtcaaa cgaacagaat ttattggtac aacatctgat acgaataaac
     2101 taactggttc aaaggtgaaa ttcaaaaacg ccgtgattcg aaatagcgca actaatagca
     2161 gtggaacgcc atctactatt tctggtactg gcgctgaagg aattgagatc ccagcagatc
     2221 aggcagtaga tctagtaact gcaggagcaa atgaagggat tggcacatgg atttattcat
     2281 taggagagaa tgtggaacaa gggagacaat cagtggaatt atttgttcct gtatccaatt
     2341 atgccgtaga caactacgtt tcaacattca catggtcgtt aacagatgct cctacagaag
     2401 ggaaagcgta aaatcaaatc aatgacttca gggagtggag ccgattcaag gccaactccc
     2461 tgaaatctgc tatgcttacg tctcagctct tattcatcaa ctcgaagcag ttttttggaa
     2521 gtcatggaaa cgttcctttg tcttttcaaa gatctttcga ccaacgagta aggagtcacc
     2581 attgaaaaat tctaacacat aatgagcaga atcaattttc tgcaattgcg ataagttgat
     2641 acagtaagat tttaatagta aaaagtaagc atacttttcc aactctgtct tcaattgttt
     2701 taaagaagta ttcactaatt tatcttctgt agttgttttg accataactt ggtttttcaa
     2761 acctttgata ctttcaatat ataaaatttc ccgaggatac aggacgagac ttccaccttt
     2821 ttgatcaata aagattttat cgacatttac gatttgctgt tctttccaat tgatctgttc
     2881 tagcacttga cgaatttgtt cagataaatt cctgtctttt ctgatatatc caatcggaag
     2941 gattttccga ttgatgatct ctactgcaaa attcgtataa gcggtgaaaa aaacaatatt
     3001 actatgtgca ttttttttac gtatttgttc ggcgacatca atacctgtga gtgattgctt
     3061 caagtcgata tcgataaaga aaacatcgtg attatcaata gtacccaact ggatcaactg
     3121 attgatttga gagatagaag tgagctgcac gatattctcg atatgatgat tgaccaattc
     3181 tttgatgatc cattcgctgt gaaactggtt atcttctatg ataaaatact ttttcatatg
     3241 caggctccta ttaaaaaaat atgtgtacat tttgaaacaa aacaatggag gaataagatg
     3301 gtcgcaacag tgacacttta tttgaccttt actttgattt tagatttagg tatctattta
     3361 ttcttttcga aacaactgct agtaaaaaac agctttggtt ttatagcttt gatggtggtg
     3421 acacttttat ttcctatccc taaagtgagc tttccttacc tagttggctt attattgatg
     3481 tttctttttt attttactac gaaaaacctg tttatcagct gtttgatcag taatcttttt
     3541 tttgctatca ctggactcag cttttttctg gtttttgatc tgatggatta tttaggaaag
     3601 agacatcttg gaacagcaag tttttttgca ctacttatcg catttatttt ctatctatta
     3661 gtaaaaagta tagacaaaca gacgagattt ctcaacttgc tttttactta tccaactgaa
     3721 cactattttg gaggtatttg tattttatta agctggggcg tgatttactt ggtattggga
     3781 agtgttcact tccgctcatc taattatctg cttctatctc ttttgtcgat agtcatcagt
     3841 tttttttctt tgtttttttc cattatgttg atcagtttcc aagtaaaaga aagacaacat
     3901 caggaatcgc ttcaactgta tcaaataaat gaagaatatt accatcatct agaggaattc
     3961 aaacatgatt ataaaagtct actgttttca ttaaaaatta ctcttcagga aaataaaaaa
     4021 gaaacgttgg aatttttaga aatcttagaa gatcattctg cagctatttt tgaaaaaccg
     4081 caaatacaac agctaacaaa tattgtatcc ccagctgtca ggggtgtctt tttaaaattt
     4141 ctagaaaaag cagaatcgga gaaaatcccg atccaagtag ttattcctgt cgaagtgaaa
     4201 acaatcccga ttgatctggt tgtttttatt cgctgtttat ctatttttat ttctaacgca
     4261 ttcgatcatc gtgtagccga tcagagtccg attacgatca atctgctgga agaaaaagag
     4321 ggattacgtt ttagtatagc gaacaaggca aatccgacga atttgacgct atcggagatg
     4381 gtcaaaagag gaaaaacctc taaaaaaaat ggcgggttag gtctatacag tgcgaaaaaa
     4441 atgttggatg tttacgaaaa tgcagaacta aaaatcgaat tttcaaaaca gaatcactat
     4501 ttttttgtag aaatgtatct ggcatctaga aagagcaaat cagcctactg acttactgtc
     4561 aaaggataag cttgaggaaa gtctacacgg agatagagac aacaacacag catattcaaa
     4621 agaaacagaa gcgtgatgac cgttgtcacc cttctgtttc ttttgctatg tagttaaaca
     4681 aagtagttga cacttccgct acttagtatt agtacgaaag tatacttcat gatactaagt
     4741 agataagaag tgaaaagcgg aacccacgat cgtcaaaatg ctaactgctt tgcttacacc
     4801 agataaaggg aagagcaata tcgcttattt taggcgtgga gaagcaagaa aatccctacg
     4861 atcacacaaa aaatgctgac ccagcagtta agagagttag aacaagatgg cattgtccat
     4921 cgaaaagtct ataaccaagt cccgcctaaa gtagagtact cgctcaccga agaaggaaaa
     4981 tcattaagag agattctagt agcgatgtct gtttggggag aagaacgtat cgaaaaacaa
     5041 aaagcctcag gggaagaagt cacattactg catacacatg gtggctacct aaattactga
     5101 tttctatgac atttatttta aataaaagaa aacaggagtt tttttaaaag catcatctat
     5161 tttttatgta aaaaaatggt atgattaatc aagtaagaaa tgattggaag aaggcaagca
     5221 aatgaatagc atggaaaaag ttaaccagtt tagagatgaa cgtaattggc gacaatttca
     5281 taacgaaaaa gatttggcta tttctatttc tttggaagca tctgaattgt tagaactttt
     5341 tcaatggaaa acgccggaag aagtaaaaga aacacaatta gaacgaatca aagaagaact
     5401 ggcggatgta ttgatctatt catacatgat ggcagacaac cttcagctgg atctagatga
     5461 gatcattgaa gaaaaattga tcaaaaataa tttgaaatat cctgtagaaa aaagcgcagg
     5521 tgtacgaaaa aaatacacag agttttagaa atgtgtcatt cggctgttgg aaagagcaaa
     5581 agaaaaacag taaaatgagt ctggagggag agaaaatgaa aaaaaaagga aaagcaaaaa
     5641 gatggctagt caatatcctc ttgttcctct tgttattagt aggactagct ttgattttca
     5701 atgaacagat caaggattat cttgtcagag agacaggaga taaatatgct atagcgaatg
     5761 taacaaaaga agatctgaaa aagaataacg ataaagatgt cagttttgac tttgatgcgg
     5821 tagaaccaat gacgacagaa ggggtcatga ggtcgcagat gagaggaaca gatctaccag
     5881 tgattgctag tatcgcagtc ccttcagttt caatcaattt accgattttc aaaggcttgg
     5941 ataatacgtc actactttac ggagcaggaa cattatctcc agatcaagaa atgggaaaag
     6001 gaaattatgc cttagcaagc catcgtgcaa cgaaccctga attgttgttt acaccgctgg
     6061 aaaatttaga gatgggtgcc aagatctatt tgacagattt agaaaatgtg tatacataca
     6121 aaacattttt taaagaaaaa gttgctccta cagataccca attactgaat gaagtcgagg
     6181 aaaaagaaat tgtcacacta attacttgtg gcgacatgga cgccgtcacg cgactagttg
     6241 tacaaggaga actggaaagt gttacaccga taaaagatgc gacagatgat atgagatctg
     6301 ctttcaatct agagacaaaa acattttagg atactgggac ataagtcgtt acagattaaa
     6361 aacagccaaa ggatatgaat cgataaggaa aaaccaattt gctgaaaaaa agaggaacgc
     6421 aaagaggtgc atctctgatt tggttgtttt ctagatagac ttgtgttcca gtttttttat
     6481 tttttatatg aaaaggcttg cataaataaa aattcgatgg tatgatgatt ttgaataaga
     6541 aatggattgt tactgtacgg caggcaaaac cagaattcag ctaagaaaca gtaggcgaat
     6601 tctaggtttt tttatttttc ttgagagggc gaagcaaaat gaaaattgat aaaattttga
     6661 ataacaatgt cgtcatttcg aaaaatggat tcggggaaga agtcgtttgt atgggaaaag
     6721 gactagcttt tcaaaaaaaa gattggggac gagatttcgc cagaagcggt ccaaaaagaa
     6781 tttattttaa gagattcttt tgctaaaaac caattccagc agctgatggc tgatattccg
     6841 gcagaggaga tcgaatgggt caaacaagta gtcgaactgg ctgaagataa actaaaagtt
     6901 gaattttcgc ctaatattta tctgacattg accgatcatc ttcattatgc gatcacacga
     6961 gcaaaagaaa atatccaact gcctaatcca ttattatttg aaacaaaaaa attttatccg
     7021 aaagaatatc aagcagcgaa agaggctctt ttgttcgtga aacaaaagac gggtgtggaa
     7081 ctttctgagg atgaagccgg ttttattgcc tttcattttg tgaatagcca acaaggaaac
     7141 gaagacatgc aagtgacgat gaccgctacc acaatggtaa gagatatact gagtatcatc
     7201 agtaaattct tcggcatcgt gttcgatgaa gaatctttga attatcagcg tatcattact
     7261 catctgcagt tttttgccca gcgttatctc aaaggggaag gatctgacga gcaagatgaa
     7321 tttctctacg cattagttca aggaaagtat ccaaaagcgt ttcattgtgt cgaacggatc
     7381 aatgagtatc ttcgacaaac gcaaaaacag gaaatgggga tcgcagagca gatttattta
     7441 acgattcata ttcaaagagt agtaagtgag aaaaaaagca tccaatcata aggattgtta
     7501 ctgtatggca ggcaaaacct ggattgaaaa aataggttca cgaatgtttg tgactgtttt
     7561 tttcaatctg ggtttttatt ttttaaataa aaaagaaaga aggaaaaaac aatggataat
     7621 caagcagttg gtcgtcgtgt atgggaagcg gtaggaggac aaaagaatgt caaaagttta
     7681 gtacattgtg ctacgcggtt gcgattcaga ttaaaagatg aatctttagc agatacgcaa
     7741 aagttaaaag aagacccgga cgtgatccaa gtcgtacaaa gtggcggtca gtatcaagta
     7801 gtgattggca gtaatgtagc agatgtttat caatcgatcg tggatgagga aggtcttgca
     7861 gtttcggagg atggaaaaga agagtccaaa aatattttga atcgtctgat cgatattatc
     7921 tctagtatat ttacaccttt tctaggggcg atggcagccg ccggggtatt gaaaggattc
     7981 ttatcattgg caacggtgat gggctggctg acagctgata gcggtactta tcaaatattg
     8041 tttgctgcag cagatggtgt ctttaccttc ttacctgtca tgcttgcttt tacagcagct
     8101 aaaaagttca aagccaacca gtttttagca gtagcaattg ctatggcact tgtgtatcca
     8161 gctatcacag cagttgctgg tgcgggagaa gctatcagtt tctttgggat cccagtgatt
     8221 ctttcaccat ctggttatac ttcttctgtc ataccaatca ttctagccgt atgggttcaa
     8281 agtaaattag agccattcgt aaaaaaagtg attccgcaat ttctgcaaat gattttagtt
     8341 ccgcttgtcg ttttagtagt gatggttcca ttaacatttc ttgctttagg accaatcggg
     8401 acggttgccg gtaatgcttt aggcggtctc ttcaactcga tttatggatt tagtccaatc
     8461 gtagcaggtc taatcatggg aagtttatgg caagtattcg tgatgttcgg catgcattgg
     8521 ggattcgtac cgatcatgtt tttgaatatc gaacaatatg ggtttgatgt attgatgcca
     8581 atgcttcttc cagccatctt ggcacaaggt ggggctgctt tagctgtagc attgcgaaca
     8641 aaagatacga aacttcgagc attagggatt tcttctacag tgacttcgtt atttggaatc
     8701 actgaaccaa ctgtgtatgg tgtgacatta cctttgaaga aaccattcat tgccgcttgt
     8761 atttctggag gtattggtgg agctattatc ggattttccg gagtaaaagc tttctccagc
     8821 agtttggtca gcttattgac gattccgact ttcattaata cggtggatgg tgtagagtca
     8881 aatgtgacag tagcagtaat agctacagga attgcttttg ttcttgcatt cgtaggtaca
     8941 ttgattttag gatttgacga acaaacacaa gacaatcaat tagaaaacaa acatgcgaat
     9001 gcaggagaac cgattacttc agcacggcat accttaaaaa gtcctttaac gggtaaagta
     9061 ctgccattga gtgaagtacc agaccaagtt ttttcttctg gcgtgatggg aaaaggtatc
     9121 gctattgatc cagaagtagg agaactagtt gcacctgcag acggagagat cacgactatt
     9181 tttccaactg gacatgctgt agggatcaca acgactgacg gagcggagat tttgattcat
     9241 atcgggatgg atacagtaga attaaatggg aatggctttg agatcttagt caaacaaggg
     9301 gatctcgtca aagcaggaga tttattgatt cgttttgaca tcgaagcaat tagagcagct
     9361 ggctatagcg taatcactcc agttgtcatt acgaatactg atgcatttgc cgatatactt
     9421 gaattagacc aaaaagagat tattgcaaac gaagatgttc tggcaattgt aaaataagga
     9481 ggaaatcagg atgcaatcac gtttttcaga aaaattttta tggggtggag caactgctgc
     9541 caaatcaatt agaaggggct tatgatcgag acggaaaagg actatccgtt gcagatgcta
     9601 tgcctggagg taagcagcgc tttgcgatta tcggcagtga agaatttgac tggacgattg
     9661 atcaagaaaa atatatttac ccgaatcatc gaggaatcga tcattacgat cgtttcaaag
     9721 aagatcttgc cttgtttgcg gaaatgggat tcaaatgtta tcgtttttcg attgcctgga
     9781 cacgaatttt tccaaatgga gacgaaggta ctcctaacga agcgggatta gaattttatg
     9841 atcagctgat tgatgagtgc ttaaaatatg atattgaacc tgtgatcacg atttctcatt
     9901 acgaaatgcc tcttcatttg gcaaaagaat acggtggctg gaaaaatcga aaactgatcg
     9961 acttctatga acgatttgct cagacagtat tagagagata cagcagtaaa gtcaaatatt
    10021 ggatgacttt caatgaaatc aattcggcct ttcactttcc agctttaagt caaggattag
    10081 taaaaagcaa tggagcagga gagtaccaaa atattttcca agcatggcat aatcaattcg
    10141 ttgcaagtag caaagccgta aaaatcggcc acgaattgcg ttcggatatc caaatcggct
    10201 gcatgattat ctatgcaaca acttacagca tcgatgccaa tccagtcaat caggcagcaa
    10261 caatgatcca aaaccaagaa ttcaattttt tctgcacgga tgtccaagta cgtggagaat
    10321 accctgcata cacagcgcgt acccataaaa aatatggagt cgatccggaa aaattagagc
    10381 aaacggaaaa agacttccag ttgctaaaag aatatccagt ggactacatc ggatttagtt
    10441 attatatgtc tacggcaatc aatgagactg atccacaagc agcaacttca gaagggaact
    10501 tgctgggagg agtaaaaaat ccgtttcttg aggcaagtga atggggctgg cagatcgatc
    10561 cagaagggct gagaatcgca ttgaatgaat tatacaatcg ttaccagaaa ccattattca
    10621 ttgttgaaaa cggtcttgga gccattgatc atatggaaga ggatggcacg attattgatg
    10681 attatcggat cgattattta cgtcgtcata tcgaagcgat ggctaatgca gtagcagacg
    10741 gtgtagattt gatgggctat acgccttggg gatgtatcga tcttgtcagt gcatcaacag
    10801 gagaaatgag taaacgttac ggctttatct atgtggatct agacgatgaa ggaaatggga
    10861 cactgaatcg atcaaagaaa aaatcttttg attggtataa agaagtaatt gcctcaaatg
    10921 gcgtaaactt gtaattaaag cagctgaatg aaaaagaaca cacttctcac atgtgatttg
    10981 tgttcttttt ttatttttta tgtgctattc ttttagtaat agtaaagcaa agggtgacgt
    11041 tatgaaaagg acacgtgtac tatacttgga agtcgcagat aaaattaaag aagatatttt
    11101 ctcaggaaaa tatccagtcg gttcgatgtt gccgacagaa agtgaattag aagaactgtt
    11161 tcaagtcagc aaaatcactg tccgaaaggc aatcgaactg ctggcatcag atgaatatgt
    11221 cgcaaagaaa agtggtcgtg ggacgacggt tctaagcaat cgtccttaca atcgattatc
    11281 caaagcggca agctttacgc aaatcttgga gaactcccga tatgaagtcc ggaaagaaac
    11341 gctggatttg caattggtcc atataaagaa ggaagatcct ttgttttcct ttttcggtga
    11401 gcaagctgtt tgttttaagc gcttatatta tttgaacaat cagccttata tttattttgt
    11461 tcattatctt ccacaagaaa tgatgcaatt cagcagagaa gaatttggca aagaatcttt
    11521 gtatcgtttg ctgacgaaaa aaggatatac tattgactca ttttctgatg atttctcggc
    11581 agtattttta acagaagaag aacaaggaat tctgaaaaca gacgcacaga tcggcatcaa
    11641 acggatacgg aaatcgtcta cgcaaattgg ggaaatgatt gaatattcgg aggcggtcta
    11701 ccatacggag ctgcatcctt accatattga ttatgaaaca taaataaa
//
LOCUS       DACBYO010000093        11606 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.093, whole genome shotgun sequence.
ACCESSION   DACBYO010000093 DACBYO010000000
VERSION     DACBYO010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.093"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..312
                     /locus_tag="IVD26_002398"
     CDS             <1..312
                     /locus_tag="IVD26_002398"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080324.1"
                     /translation="QQEKQVEKLERQEEIKEMGYNKYGGLDMTIENIPRIKEEIERFE
                     KGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAIIDSGRVTQWKKIRPFI
                     F"
     gene            339..2150
                     /locus_tag="IVD26_002399"
     CDS             339..2150
                     /locus_tag="IVD26_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP6080325.1"
                     /translation="MNENGEFEESKKYQATSEEEKAAVRELLEEAVPTDFLKEKENDH
                     FYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYYKFYFEEVKNGEVV
                     DQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKEQMQSKETKTKQKG
                     YQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFPERSFRNQLLIEEQ
                     FPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGFVREIEATPEDKKR
                     IESGQIEVIKKTYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQLDKKGQSELQAGIQ
                     AVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNTRNTPTQHLATSIH
                     ELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYIAAWTKNGQTLDDK
                     EAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQEHKNTVETAENKNI
                     VPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSE
                     EFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2211..3671
                     /locus_tag="IVD26_002400"
     CDS             2211..3671
                     /locus_tag="IVD26_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAP6080326.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFIPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3682..5886
                     /gene="topB"
                     /locus_tag="IVD26_002401"
     CDS             3682..5886
                     /gene="topB"
                     /locus_tag="IVD26_002401"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP6080327.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6125..6718
                     /locus_tag="IVD26_002402"
     CDS             6125..6718
                     /locus_tag="IVD26_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6080328.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            6734..7633
                     /locus_tag="IVD26_002403"
     CDS             6734..7633
                     /locus_tag="IVD26_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAP6080329.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            7636..8121
                     /gene="ssb"
                     /locus_tag="IVD26_002404"
     CDS             7636..8121
                     /gene="ssb"
                     /locus_tag="IVD26_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP6080330.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            8487..8747
                     /locus_tag="IVD26_002405"
     CDS             8487..8747
                     /locus_tag="IVD26_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080331.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9188..9394
                     /locus_tag="IVD26_002406"
     CDS             9188..9394
                     /locus_tag="IVD26_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAP6080332.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9394..9645
                     /locus_tag="IVD26_002407"
     CDS             9394..9645
                     /locus_tag="IVD26_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080333.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            9660..10097
                     /locus_tag="IVD26_002408"
     CDS             9660..10097
                     /locus_tag="IVD26_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080334.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFESIEKNGAFYTIESEEKDNE"
     gene            10090..10797
                     /locus_tag="IVD26_002409"
     CDS             10090..10797
                     /locus_tag="IVD26_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080335.1"
                     /translation="MNKVVYQLTTEDVSQFLTSKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
     gene            11178..11357
                     /locus_tag="IVD26_002410"
     CDS             11178..11357
                     /locus_tag="IVD26_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080336.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
BASE COUNT         4295 a         1947 c         2411 g         2953 t
ORIGIN      
        1 caacaagaaa aacaagtaga aaaacttgaa agacaagaag agataaagga aatgggctat
       61 aacaagtacg gcggactgga tatgacgatc gagaatattc caagaatcaa agaagaaatc
      121 gaacgctttg aaaaaggtga atcgactttt tcagccgcta cgatccgaaa ataccaacgg
      181 aaattggaaa cattagaaca gctgaaagaa agatcggaaa aaggaaaaga aaaccttctt
      241 cctgaagtac aagcaatcat tgacagcgga cgagtgacgc aatggaaaaa aatccgacca
      301 tttattttct gaaaggctat cgaaaagtcg ctttagaact gaatgaaaac ggggaatttg
      361 aggaatctaa aaaataccaa gccacgtcgg aagaggaaaa agcagctgtt cgtgaattac
      421 ttgaagaggc tgtaccaact gattttttga aggagaaaga aaacgatcat ttttatcgag
      481 tagaattcaa cgaaaatgat ccagaaaaag gattgaaaag ttatggtggg gagatcgtaa
      541 cattcgaatt gatcgatcaa ctcaaaacgt tggataacca atacgccgca gaagcaggtt
      601 attataaatt ctattttgaa gaagtgaaga acggagaagt agtcgatcag atccgaatgg
      661 atctagggga tggcgtcaac agtaatcaac ccatctattt agagttagca aaattgtgcg
      721 aacaagtacc tgagaaggaa caaaaacaat cggtcaaaaa tgaacctgtt tcgaaagaac
      781 aaatgcagtc gaaagaaaca aaaacaaaac aaaagggcta tcaaaaacga acggcagaag
      841 agattaaaca agaagttaaa tccctttcgc aacaggcact ggatgcggtg aaaaagcata
      901 ctcattctcc tgaagacgtc aaagaacttt tgaactttat gtctcgtttt ccagaacgat
      961 cctttagaaa tcaattattg attgaggaac aatttccagg tgcaacggct tgtttaggtc
     1021 gtgccgcgtt gaaaaaagaa ggaatctata tcaaaaaagg ggaacaaggg aacaagatct
     1081 ttgtcagaaa aacggtcaaa ggattttatg agaaaggacg tggctttgtt cgagaaatag
     1141 aagctacacc agaagataaa aaacgaatcg aaagtggtca aatcgaagtg atcaaaaaaa
     1201 cttactacac gattgaaaaa gtgtttgata tcacacaaac acagttaaaa cctgaagact
     1261 atccgaaaat ctttccgaac cgtgtctttg attttcaatt ggataaaaaa ggacagtcag
     1321 aacttcaagc tgggattcaa gcggtagcca acaatattgg aatacaaatt cgagatatga
     1381 cagaaagtga agtctatcaa agagaattag gacaagcacg tggggcgtat gttcgtaacg
     1441 aatttactgg cgaagaagaa atcgtcatga atactcgaaa tactcctacg cagcatttag
     1501 ctacaagtat tcatgaatta gcccatgcaa gaatgcacaa attttcagaa ttagataccg
     1561 caactaaaga attgcaggca gaaatgactt cttatattgt gtgcaaacat tttggaatgg
     1621 acacgtcgga gaaagctatt ccttatattg cagcatggac gaagaatggt cagacgttgg
     1681 atgataagga agcggcggaa cgtgggaaaa tcatgaatga tgtcagccgt gtcgcaaatg
     1741 aattcattca aaccatttct aatgaaatca atcaatacag agaaagagaa ccagagatcc
     1801 aaccagcaga agtgaagcag gagcataaaa atactgtaga aacggcagag aataagaata
     1861 ttgtgcccgt tggttcactt tggatcgaca agaaagacgg gaaagtaatg gaagaagata
     1921 cgggtcgaac gttacatttg aaggatgcgg cgtttattga agatccgcag cataatcaag
     1981 tgattttaaa aggaaaaagt tatggaaaag agattcaaac ggcgttacct tcagaagaat
     2041 ttgcgctagg aaatccattc cgattttcac ttgaaacagt gtcagaagtg gccaaacgaa
     2101 aaaatgaaat ctattatgaa caacaattgt cacaaaaaga acgcgtataa aacaagtaaa
     2161 aaagactatc tgaaaaacgg atagtctttt ttcttttggg aggtttgaaa atgaccgaaa
     2221 aaaaaatgag tcttattgat cgatgtaaac agatcgatat agtggatttt gctcgaaaca
     2281 atggaatggc tgtagtcaat aaaggacgag actatcgctt agaagaccat gattcatttg
     2341 tttttgatcg aagaaaacaa cgtttttatt ggaacagtca aaatattagt ggcgacatta
     2401 ttgaattagc taaacttttt ttcatagaca aagagatcca agactctaag caacaattta
     2461 aagcagccac tgattttatt ctaaagaatg aagacaaaac agaacgagtg gaaaatcttc
     2521 attttgaaac agaaaagtac aaagatcacc ccgttgatta tcaaccactc acagaaaaag
     2581 gaaggaatta tctgaaggaa gaacgaaaac taccagagtg gctgattgat tatgcagaaa
     2641 aagaagggtt gattgccgaa ctaaagccaa aatatgaacg gcaaaatttc ttagttcgag
     2701 acgatcgttt agatcatgcg gtcgcctttt tatggaaaga tccacagaca aaagagacag
     2761 taggggcgag ttatcaagga acgttcattg attatgaacg ttttggtgag agaggcacat
     2821 ataagcatat agataaaaat tcgacagcga atcatggctt taacctaaag atcggtgacc
     2881 ctaagcagtt aaaatttttt gagagtagta ttgatttact tagctatgct gcactgaatc
     2941 gtgatcagtt aaacgatacg tggttagtct ctatggaagg gttaaaacac catgtgatca
     3001 gtcattattt tggtgaggca gtatctgaat tgagaaagaa acaagccttt cctcaatcca
     3061 tcgagatttg tgtggataat gaccgtgcag gacatatttt ctacgaaaaa gaacaattaa
     3121 tgggcgcagt cgatccattt acgaatcaga aagtacgttg tgaacgagga atcgctaatg
     3181 attggcaagt gccaaaagaa tacaaaatca tttatgaaga agtcgcaaaa gaagaaaagg
     3241 tcacaccaga agctattatg gccatacaca agacagaaaa caatctgcaa ttaacgaacc
     3301 aactggtttc cgctcacaaa gtaaatgcgt tttttggcca gcagctttct gttaacgatt
     3361 caatagaagc cattaatttg aaagatattt gtagagaagt cgcaaaagaa ttaaaagttt
     3421 gtgaacgcgt ggatggtacg tacgattttg atcgttttta tcaagaaaaa ggggatatta
     3481 atgcgcagat tcttttctct tataaagcag aacaatacta caaaggctat aaaaatcatg
     3541 aacatgaatt tatacctgaa gtaaaaaagg actggaacga tcaattgaag catgagatcc
     3601 agcaacaaga aatcagaaag caaaaacgtg ccatgttgtt tcaacaaggc agacaacaag
     3661 aaagggagtg aaatcgtcat gatgaaaacc gttattttag cagaaaagcc gtcacaagcg
     3721 aaagcttatg ccgatagctt ttctaaagct acccgaaaag atgggtattt tgagatccaa
     3781 gatcgattgt ttacaggaga aactgtgatc acgtatggtt ttggtcattt agtcgagtta
     3841 gattcgcccg atatgtacga tgaaaaatgg aaacaatggg cattagaaca tttgcctatt
     3901 ttccccaatc aataccacta tcatgttcct aaagataaga aaaagcagtt tagtgtcgtc
     3961 aaacgacagc tgcagtcagc tgatacgatt gtgatcgcga ctgatagcga tcgtgaaggg
     4021 gagctgattg cctggtcaat cattcaacaa gcaggcgcca atcaaggaaa aacctttaaa
     4081 agactttgga tcaactcctt agaaaaagaa gccatttatc agggattcca acagttacga
     4141 gacgcagaag agacctatcc aaaatttgaa gaagtacaag cacgtcagat cgccgattgg
     4201 ttaattggga tgaacggtag cccactgtat agtttactct tgcagcaaaa aggcatacca
     4261 ggaagttttt ctttaggtag agtccaaacc ccaacactct atatgattta tcaattgcag
     4321 gaaaagatta gaaacttcca aaaagaacca tattttgaag gaaaagccca agtaatcgct
     4381 caaaatggcg catttgatgc gaagcttgat ccaaatgaaa cccaagcgac acaagaagca
     4441 tttgaagcct atttaaaaga aaaaggtgtt caattaggaa aacagccagg tacgatcctt
     4501 caagtcgaaa cagagaaaaa aagtgcggct agcccacgtc ttttttcttt atcgagcctt
     4561 cagtctaaaa tgaatcaact catgaaagct agtgccaaag atactttgga agccatgcaa
     4621 gggttgtatg aaggaaaata tctaagctat ccgcgaacgg atacccctta tattacggaa
     4681 ggggaatatg cgtatctgtt ggatcactta gacgaataca agcatttttt aaaagccgaa
     4741 gcgattccga ctcctattca tacaccgaat agtcggtatg tgaataataa gaaagtccag
     4801 gaacattacg cgatcattcc tacaaaaacg gttatgacag cagcggcttt tgaacaacta
     4861 agtccactgc agcaggctat ttatgaacaa gtgttaaaaa caacggtggc catgtttgcg
     4921 gaaaagtata cctatgaaga aacaacgatc ttgacgcaag ttcagcagct tcagttaaag
     4981 gcaatcgaaa aggtgccgct agatctaggt tggaagaagt tatttggaaa agagagcgac
     5041 ggaaaagaga aggaagaaga gccgctactt cctaaagtga caaaaggaga aatggtgacg
     5101 gtggatctac aagttcttga aaaagaaacc aagccaccac agccttatac cgaaggtacg
     5161 ttgatcacgg cgatgaaaac agctgggaaa accgttgata gtgaagaagc gcaatccata
     5221 ttgaaagaag tggaaggaat cggtacagaa gcgacacggg cgaatattat tgaaaccttg
     5281 aaacaaaagg aatatatcaa ggtagagaaa aataagctcg tggtgacgaa taaagggatt
     5341 ttgctttgcc aagccgtgga aaaagagccg ctgcttacga gtgccgaaat gaccgccaaa
     5401 tgggaaagct acttgttaaa gatcggtgaa cgaaaaggaa cacaaaccac ttttctagcc
     5461 aatatccaaa aatttgtctc tcacttattg gaagtcgtac cagggcaaat ccaatccact
     5521 gattttggat cgacgttaca agaagtgaaa gcagccagtg aaaagcaaga agccgcgcgt
     5581 catttaggaa tttgtccaaa atgccaggaa caagaagtct tactctatca aaaggtggca
     5641 gcatgtacgt ctgaagcctg tgatttcaaa ctatggacaa cgattgccaa aaagaaactt
     5701 acagcgacac agctgaaaga gatcattcaa aatagccgaa caagccaacc agtgaaaggg
     5761 ttaaaaggtc agaagggttc gtttgaagca acgattgttt taaaagaaga cttcactaca
     5821 ggctttgaat tttctgaaaa gaaaaaaacg aacttcaaga aaagaacacg acgcactaca
     5881 aaataatgga gggttaatct tatgcgtaat acaacacaca aacaacaaga aatcgaaaat
     5941 caaaaagcca aaattcgttc agaacaggaa aaaatgcgtg ccagcaaacg aagactgcag
     6001 caattgaaga accagcagcg gattcaaaaa gaaatcgaat tagatcgata aattcctttc
     6061 ttgttaatat aaaactaaca tgttatagtt gtgttagttt tatattaact ttaggggaag
     6121 agtaatgaaa gacaaaatcc aatgtatttt tgataaacat aatggcaacc tatccttgaa
     6181 ggatgctaga agtgaaggat tatcgcctat gacgttagat cgattagccg aaaaggataa
     6241 aatagaaaag gtagcaccag gtttctatac cttaaaggat gcgttcgtgg atgaattgta
     6301 tctcgctcag agtatctatt ccagagggat tttttctcat gagactgcgc tcgatctttt
     6361 tcaagtagga acatatatcc ctaaaaagat caatatgatg tttcctaaag gatacaatgt
     6421 atcaaaggag aaattagatc agtatgccat tcaaccgcat tacactaata aagaaaattt
     6481 tgacctggga gtcacagaaa cagaaagctt ttacggcaat aaaattttag tctatgattt
     6541 agagcgaacg ttatgtgaca tgtggaatcc aagatacaaa gcaagcgtag aggtaaaaca
     6601 agaagcatta aaagaatata tgacaagtac cagtagaaat acaaataagc taagaagata
     6661 catggatatt ttaaaatcac caaaagaaat gactttgtat atgttgccac tttattgaga
     6721 ggagtaaaga tgaatgacac cgacacaatt taaagagaaa acaagaaatt tcgcagcaga
     6781 gaaacattta aacccacaaa ttgtccaaag atattatatg atggaaaaat tattagaatg
     6841 tattgttgaa tcgccttatc atgatgattt tgtattaaaa gggggatttc tgattggatc
     6901 aaaatacggg ttagaaaacc gttcaaccgt tgatattgat acgacttatc gaaattcgaa
     6961 actaacaaaa gaaaagttag aaactgtttt ttctgaatta acagctaatc ctacaaaaga
     7021 tggaattcgt tttgaattaa agggattaac agagacgagg gaagccgatt attatccagg
     7081 ttttcaagca aagtttattg cttatcttga aaatgcacgt gtacctttta aattagatat
     7141 tacttcaggt gattctatta ttccagcagc attgatgtat gaacacaaat taatgtttga
     7201 agataaaacg attcatattc cagcttatcc tacggaacaa attctagctg aaaaattaca
     7261 tgccacgttt agttttggaa aagataattc gcgcatgaaa gatttttatg acctgtatat
     7321 gattccgaaa ttagaacgta tcgatgagaa aaatttgtat aagagtgttc aaggaacatt
     7381 caaggaaaga aataatcaat cggtgtttaa gcatttgtat gatcaggaaa tgcctcaatt
     7441 ggtgaaagat gagggcttga gagaaaagtg gaaaagatac caacaagaaa actattttgc
     7501 caaagacatt tctttcgaat ctacactaac ttccgttgat tccctgatgc aatcaattgt
     7561 agagcaagag aaggcagaac gaaaacaaaa ttttaagaga tcacaacaaa tgaatcaaga
     7621 aatggagaga taaagatgat caataatgta actttagtag ggcgattaac taaagatcca
     7681 gatttacgtt ataccgcaag tggcacagca gtggcgactt tttccctagc cgttaatcgt
     7741 aatttcacga atcaaaacgg caatcgagaa gctgatttta tcaattgcgt gatttggcgc
     7801 aaaccagcag aaacgatggc gacattagct aaaaaaggca gcttgatcgg cgttgtcgga
     7861 cgaattcaaa cacggactta tgacaaccag caaggacagc gtgtctatgt gactgaagtt
     7921 gtggccgata atttccaact attagaaagt aaagcagcga cagaaagccg tatgcacgct
     7981 gatcaatcgt ccagcagtcc aagccctacc acctttgaac aacgggatac agcgacgcct
     8041 aacaacaatg gattgaacgc ttcacagaat ccatttggtg gacaatcaat cgatattagc
     8101 gatgatgatc taccgttcta agtagcattt tctattggtt gcatttgcta cggtttatgt
     8161 tataatttag acaacaaaaa gaattttcaa tctataacca aaaaccacta gctggcgggc
     8221 tagtggcttt cttttacgtt tctattataa gaattaacgg gtaggcttac tgtctttctt
     8281 ggcaaattta caatcaagcc atttgcagat atagtgcgcg gctacttctg ccatgattgc
     8341 aaaaacaaaa tcaaaaagaa ttttcaaacc tataacctcc tccccttgcc agattaggcc
     8401 ggggtagcag acagcaagac tattatagca taattgaaat atccaaatga ttggattttt
     8461 gctataattt tagcgaggtg attgtgatga acaaatatgt tggtttgctt gataaaatcc
     8521 gagtaataaa aacgcaaccg ttattggttc gctttacttt acaaacgatt catgaatcga
     8581 ttaattgtgt agttgcagat attgaaatta tcgataaatt gctaattatg gatgatggaa
     8641 aatacaatat tgccgtcaca ggtcacttca ataaacgaaa tcagctagtt attgctagca
     8701 tgtatgttag aaatcccgat cattttacgc gatcgatggg catataaata aaagaagagt
     8761 tgtagtccta aatgaggatt gcagctcttt ttgttttaca tagaaacagg aaaagacctt
     8821 tttaggaaga cacaagtgcc ttctcaattg aaaaaccttt ctctcactcc aaccgccacc
     8881 gccgttcgag aagaaaggaa gtgaacgctg cacgttcact aagatatggt gtcttgcaaa
     8941 gcaagacaaa atagacaaaa cttcctctca ccaaaaggtt cgttcctgtt cgttatctct
     9001 ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     9061 gggtaaatgg cacgctgcgc gcccttgtcc ttgtcgcttt tcgttgattt attctggcca
     9121 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     9181 atcaaacatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     9241 ctatcatgca ccacatactg ttgaatgcga ttgtggagaa agagcgaaat gtatcaaaag
     9301 ctatcgtttg tatcaatgtc caacatgcgg gaaaaaatat accttgtctt atggcgatta
     9361 cattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cacaacacaa attattgact
     9421 gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa agtagcagaa
     9481 gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga tgcaccgact
     9541 atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca agaaaacatg
     9601 gaaacttatg aaatcgaata ttggttaacc aaattagaga actaaaaagg agaaaaaata
     9661 tggctcaaaa ttactatgac gaatttgtca aattaccttt ggataaaatg gcacaaaaaa
     9721 tggaggatat gacgttccta taccatgaaa cacgtgtacc caaaaaacat tacaaggaaa
     9781 aattgtcagt cgcagtggaa gaaatgattg aatcaggtgt cgaaatgaat ctcattgcga
     9841 cgtactatcg aacactggaa gaactgaaaa aacaaaatgg aaaatggttt ttccaagcct
     9901 tactatgctt ggaagtaggt gtcaaaccaa gcactatcaa accttccgaa tatcaagcct
     9961 tagaactgac ttatgcaaaa ttcgcacaga ttaagaaagc taaagcaatg gctagcgact
    10021 ggctagatac ttttgaaagt atcgaaaaaa atggtgcatt ttatacgatt gaatcggagg
    10081 agaaagataa tgaataaggt ggtttatcag ctaacaacag aagatgtttc gcaattttta
    10141 acaagcaaag aacacttgaa tgaagtaatc agacggattc aaaaagactt tagttgtatg
    10201 gaagaaatga agtactttat tcaaagagtg gaagaacagt tgtatatgga aagcgaaaca
    10261 agtcaaacga aggtcacagt cagccataat catttagacg tgtataaacg tcgtcctgaa
    10321 acggtaaaaa aaggaacaga gcttctacga ctagaaacag aaaaatacat catgaatgtg
    10381 tacctagaaa ggagtgagct ggtcgaaaac tttgtcagct acacgatttg taggaaacac
    10441 tattactcag aatcagaata ttattcaatt ttcgagagca tggaattaat ggaagaagaa
    10501 atggaagagc taaacagcaa aaatgcgacg gtagacgatt attaccttgt atttactagg
    10561 tttttgacgt gtgggacgga atctatcgtg ttaatgggaa tggattatga actcgctgta
    10621 cccgaagcat ttttgaggga atatgtagaa gaagtagata acccaggcga cgactggtac
    10681 acgactttaa ctgatttttt agacacctac acttacgacg atacagaaga aatccaaaat
    10741 gaacttgacc gtaaacgaat gccatatcaa cgatttgaaa ggaaaaaagg taaataacca
    10801 tttataccga aaagtgagga tgtgtgaaat aagaacaaaa aaccttgaaa ttaagggaat
    10861 ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataag
    10921 cgggcaaagc ccgataacct aagagaaaga aggagatcca tatgaataaa atcattcctc
    10981 tattgttcgt actgtttgtt ggcgagatac ttatgcgtca tgctgcagct gtacatttaa
    11041 acttcgtagt attcttagga atactggtat tttgtttgat cttttggcga tttgtattag
    11101 cccttgtgag tctactattc aagatgattg cagccatatt tttcataggg ttatttcgat
    11161 gaaaggagag agtactaatg ccaattgcaa taggaaataa acggttaccc gtgacattag
    11221 atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtacggaaaa agtgaatcta
    11281 agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga tttgatatac
    11341 cagcactaaa aaagtgacgt cacttttcat ttgaagaaac aaaagtgata gcacttaatt
    11401 gttcctacta tttagaatat tttctatgtc ctttttattc cattttgtat caataactat
    11461 gaaatcttta aagtatccag aagagattat ttttagatca atttttttct tacctgattc
    11521 taaagatttt gttttcttaa acatattatg atttcctttc gactattttc atataaatgt
    11581 taacatagtt tatggattca tggaat
//
LOCUS       DACBYO010000094        11289 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.094, whole genome shotgun sequence.
ACCESSION   DACBYO010000094 DACBYO010000000
VERSION     DACBYO010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11289
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.094"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="IVD26_002411"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="IVD26_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAP6080337.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="IVD26_002412"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="IVD26_002412"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAP6080338.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="IVD26_002413"
     CDS             complement(2169..2906)
                     /locus_tag="IVD26_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP6080339.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="IVD26_002414"
     CDS             complement(2997..3524)
                     /locus_tag="IVD26_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAP6080340.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="IVD26_002415"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="IVD26_002415"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAP6080341.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="IVD26_002416"
     CDS             complement(4401..4886)
                     /locus_tag="IVD26_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAP6080342.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="IVD26_002417"
     CDS             complement(5039..5236)
                     /locus_tag="IVD26_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080343.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="IVD26_002418"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="IVD26_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAP6080344.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="IVD26_002419"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="IVD26_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAP6080345.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="IVD26_002420"
     CDS             9211..9423
                     /locus_tag="IVD26_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAP6080346.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="IVD26_002421"
     CDS             9425..11104
                     /locus_tag="IVD26_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAP6080347.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3274 a         2434 c         1981 g         3600 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaatacggct cttcgtcaat gagtgttggt
    11281 gaagaaatt
//
LOCUS       DACBYO010000095        11066 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.095, whole genome shotgun sequence.
ACCESSION   DACBYO010000095 DACBYO010000000
VERSION     DACBYO010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.095"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            126..1085
                     /locus_tag="IVD26_002422"
     CDS             126..1085
                     /locus_tag="IVD26_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6080348.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMRGKRKPNGHQEKRGKQQYQRSIHDRSDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            1591..2193
                     /locus_tag="IVD26_002423"
     CDS             1591..2193
                     /locus_tag="IVD26_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6080349.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            2209..2886
                     /locus_tag="IVD26_002424"
                     /pseudo
     CDS             2209..2886
                     /locus_tag="IVD26_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            3398..3694
                     /locus_tag="IVD26_002425"
     CDS             3398..3694
                     /locus_tag="IVD26_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HAP6080350.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            3695..4111
                     /locus_tag="IVD26_002426"
     CDS             3695..4111
                     /locus_tag="IVD26_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAP6080351.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            4131..5675
                     /locus_tag="IVD26_002427"
     CDS             4131..5675
                     /locus_tag="IVD26_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6080352.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            5818..6042
                     /locus_tag="IVD26_002428"
     CDS             5818..6042
                     /locus_tag="IVD26_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6080353.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            6057..6926
                     /locus_tag="IVD26_002429"
     CDS             6057..6926
                     /locus_tag="IVD26_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAP6080354.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            6907..7641
                     /locus_tag="IVD26_002430"
     CDS             6907..7641
                     /locus_tag="IVD26_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6080355.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            7674..8582
                     /locus_tag="IVD26_002431"
     CDS             7674..8582
                     /locus_tag="IVD26_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAP6080356.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            8579..9121
                     /gene="sat4"
                     /locus_tag="IVD26_002432"
     CDS             8579..9121
                     /gene="sat4"
                     /locus_tag="IVD26_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAP6080357.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            9214..10008
                     /locus_tag="IVD26_002433"
                     /note="aph(3')-IIIa"
     CDS             9214..10008
                     /locus_tag="IVD26_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAP6080358.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(10116..10304)
                     /locus_tag="IVD26_002434"
                     /pseudo
     CDS             complement(10116..10304)
                     /locus_tag="IVD26_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10284..10856
                     /locus_tag="IVD26_002435"
     CDS             10284..10856
                     /locus_tag="IVD26_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP6080359.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
BASE COUNT         3894 a         1751 c         2385 g         3036 t
ORIGIN      
        1 cccgcactat gccattacat ttatatctac gcgaattgta aaattaagtt agaaaaataa
       61 aaaggcattt atggtacact caaattgtat ttccgacgaa agaaaacaaa ggagtgtaac
      121 cataaatgac ctacaaacat cttaccatag acgaactgac aatgatagaa tcatattatc
      181 ttcaacataa taagccggtt gaaatcgcta accgaatggg acgtgctata caaactattt
      241 ataatgtagt caataagttc aagcaaggca agactgctct tgattattgg caccagtata
      301 aagaaaataa gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat gaagtagatt
      361 acattaaaga gaaagtcact cttggttgga cgcctgacgt cattatcggg cgaaaagaaa
      421 ggtctgtttc atgcggtatg agaacacttt atcgtttatt ttctaaagga atatttgata
      481 ttgacacact accgatgaga ggtaaaagaa aacccaatgg ccatcaggaa aaacggggaa
      541 aacaacagta tcagcgctca atccatgatc gatctgataa ttatcctgat ttcaattctg
      601 agtttggtca ccttgaaggt gatacgatcg ttggcattca tcataaaagt gccgtcatta
      661 ctttagttga aagattatct aaagtcatta tcacgattaa acccaacggc cgtaaggcat
      721 tagatattga aactgccctt aatcaatggt tttctcgctt ccctaaaaac ttctttaaat
      781 ctattacgtt tgactgtgga aaagaatttt ctaactggaa agccattagt aaccaacatg
      841 atattgatat atattttgcg gaccctggaa caccttctca acgcccatta aacgagaatt
      901 ctaacgggat tctgcgtcgt aatggactgc cgaaatcaat ggattttaga aaagtgaatc
      961 agacatttat ttccagtgtc agcaatcaac gtaatcatat tccaagaaaa tcattgaatt
     1021 acagaacacc aatcgaaata tttttgagct atgtacaaga agcattttat tctagcttaa
     1081 tttgacaaat catactatga tacgtgtttg tttttctgtg ctgtttagtg aatgattagc
     1141 agaaatatag agagtaagat tttaattaat tattaggggg agaaggagag agtagcccga
     1201 aaacttttag ttggcttgga ctgaacgaag tgagggaaag gctactaaaa cgtcgagggg
     1261 cagtgagagc gaagcgaaca cttgatcttt taagttgcta tctttttaag gtcaatagag
     1321 tatacttatt tgtcctaata tggttttagc agtataattg acttggtgaa taggtcattt
     1381 aagttgggca taataggagg agtaaaatga aaaaatttat ttatcgagtt ttagaaaatg
     1441 acgaagtggt ggctattttt aatgagcaac aatatgcgca agattttatc gcttacgaaa
     1501 agacaatttc tgataagcaa tttgaaattg aaaaagtaga tatagctgat tggttattgc
     1561 aaccgagaga attttagagg ttggttgaaa atggctaaaa ttggttatgc acgtgtcagt
     1621 agcaaagaac agaacttaga tagacaactg aaagcgttag agggcgtttc taaggtcttt
     1681 tcagacaaat taagcggtca atcggtcgaa cgcccacaat tacaagctat gcttaactat
     1741 attcgtgaag gggatatagt tgttgttact gaattagatc gattaggacg aaataataaa
     1801 gaattaacag aattgatgaa tcaaattcaa attaaggggg caaccctgga agtcttaaat
     1861 ttaccctcaa tgaatggtat tgaagatgaa aatttaagac ggctgattaa taatttagtg
     1921 attgaattgt ataagtacca agcggaatct gaacgcaaac gaattaaaga acgccaagcc
     1981 caaggaattg aaattgctaa gaaaaaagga aaattcaaag ggcgacaacc taaattcaaa
     2041 gaaaatgatc cacgtttaca acacgctttc gatttatttt tgaatggttg ttccgataaa
     2101 gaagttgaag aacaaactgg aattaatcgc cgaacgttta gaaggtatcg atcaagatac
     2161 aacgtgacag tagatcaaag aaaaaaacaa tgaaaagagg gatagttaat gagtacggtt
     2221 attttagctg aaaaaccaag ccaggcatta gcctacgcaa gtgctttaaa acaaagcacc
     2281 aaaaaagacg gttattttga gatcaaagac ccactattta cagatgaaac gtttatcacc
     2341 tttggttttg ggcatttagt cgaattagca gaaccaggtc attataacga aaagtggcag
     2401 aactggaaac ttgaatcttt gccgattttt cctgatcgat acgattttga agttgcaaaa
     2461 gataagggaa agcagtttaa aattgttgct gaacttctca aaaaggcaaa tacaattatt
     2521 gtcgcaacag atagcgacag agaaggtgaa aatatcgcct ggtcgattat ccataaagca
     2581 aatgcctttt ctaaagataa aacgtataaa agattatgga tcaatagctt agaaaaagat
     2641 gtgatccgaa gcggttttca aaatttgcaa ccaggaatga attactatcc cttttatcaa
     2701 gaagcgcaaa cacgccaaat tgccgattgg ttgatcggca tgaacgcaag ccctttatat
     2761 accttgaatt tacaacaaaa aggcgtacaa ggtacatttt cattaggacg tgtacaaaca
     2821 ccgactttat atctcattta tcaacgccag gaagcaatag aaaactttaa aaaagaacct
     2881 tttttcctga ataattcata gttttactaa tagtctttcc taacattgat ttaatagtct
     2941 ttaaagtatt ctgcttcatc acccattagg tgatgaaaaa agaacccctt tctgatttag
     3001 cggacaaata ctttgaccta atctcagaag atataaaaga aaaaataata aaatatccga
     3061 tttatacttt gtataaagaa ctaaagtagt tagcaaatca tttacagcaa atcactatgt
     3121 tccacatacc attttacata cttaccttat ccacgacaca tgttgagata gtatcgaaga
     3181 taaagaaagt tgctccatgt tgtttttgcg agatggggaa atcaaagcca cattgacaac
     3241 catgatgaat aagcttgctt tcagtcataa gctaatccta gaaccacttt tcaagtcagt
     3301 tagccaaatc gatgaagaaa gcgaccgtga aagaatggac gctattgata agctaatgga
     3361 gcaactattg gaagaacgca atacccttat tgcactgatg tccaaaggtt tcctagaacc
     3421 tgctcttttt aatcaggaac gaaatgtttt agatagtgag attaaaaatc ttactaccga
     3481 aaaaacaaac ctggtaacga actctgcgag tggggttttg cgagcaaacg agataaagga
     3541 cctcattaat tatgtgtcag cagataattt taatggtgac tacacggaag aactatttga
     3601 agaatttgta gtgaacatca ttgtaaattc cagggatgag ctgacattca atttgaaatg
     3661 cggtctttcc ctgaaagaaa aggtggtgag ataaatggca tatattccat atggatacaa
     3721 aattcaagat ggagtggtta ctgtcgatga aaaggcagca ggtcaagtaa aggtattctt
     3781 tgagaaatac atatcaggac tatcccttac agtggctggc gaacaggcag gtattgaaaa
     3841 gacacattct gtgatggggc gcattttgaa aaacgtcaac taccttggaa atgatacgta
     3901 tccagcaatt attgataaag agatatttga taaagctgaa gaagttagag ataaacgtgc
     3961 aaaggattta ggacgagtgg tagagcttgc cgctttcacc tctccccctc ccaaagaacg
     4021 attcaaaatg aaaaaggcag ataataagat gccagtggat ccttttgaac gagcagaata
     4081 cttatacagt ctgatagaaa gcgaggaata aagtgacaga gaaaaatata atggttattc
     4141 ctgctcgtaa aagagtagga agtacagccg caaaagaaaa gataaagaaa cttcgtgttg
     4201 ctgcctattg ccgtgtttct acagaaacag aagaacaaaa ttctagctat gaggttcagg
     4261 tctcacacta tacagagttt ataaagaaaa ataatgaatg ggagtttgct ggcatctttg
     4321 cagatgatgg tatctctggt acgaacacta aaaagcgtga cgaatttaat cgcatgattg
     4381 cagagtgtat ggacggtaac atcgacatgg ttattacaaa atccatcagc cgatttgcgc
     4441 gtaacaccct agactgcctt caatacatta gacagctcaa ggataagaac atatcagttt
     4501 attttgagaa agagaacatc aacaccacgg atgccaaagg tgaggttttg ctgactatta
     4561 tggcatcttt ggcacagcag gaaagccaga gcctttcaca aaacgttaag cttgggctac
     4621 agtaccgata ccaacaagga aaggtgcagg tcaaccataa gcgatttatg ggctacacga
     4681 aagatgaaga tggaaattta actattgtcc ccgaagaagc tgagattatc aaacgcatct
     4741 accgagaata ccttgagggt cagagtctag tgggcattgg tcgagccctt gaaaaggatg
     4801 gtattttaac agcagcggga aaaccaagat ggcgaccaga atcagttaag aagatacttc
     4861 aaaacgaaaa atacatcgga gatgcccttc tgcaaaagac tgtcacagta gattttctga
     4921 ccaagaaacg agtgaaaaat gaagggcatg ttccccaata ttatgttgaa aatagccatg
     4981 aagcgattat tcctaaagag ttatttttgc aggcgcaaga agaaattcat cggagaagca
     5041 atatctacac aggagaaggc aagaacaaaa gaatttacag tagcaagtac gctttaagtg
     5101 ccatcacctt ctgtggagat tgtggcgata tttatagacg ggtctattgg aatatccacg
     5161 gaagaaaaga atttgtctgg cgatgcgtga ctagaatcga gcaaggtcct gaagtttgta
     5221 agaaccgaac cgtaaaagaa gatgaacttt atggtgcagt aatgactgcg attaataagc
     5281 tacttgcagg tgggaacaat atgataaaga cactggaaga gaatattcat gctgtgattg
     5341 gcgaaaccac agaataccaa atttcagaga ttaacaactc actagaggaa aaacaaaaag
     5401 aactaatcaa gctggcgaac aagggtcaag actatgacca cttagcagat gagattgatg
     5461 agctgagaga caagcgacag atccttttag tagaagatgc ctccctcagt ggcgagaacg
     5521 agcgaatcaa tgagctgatt gaatttatcc gcaagaacaa attccgcacc ttagaatatg
     5581 atgataagct tgtaaggaag ataatccaga gcgttacagt ctatgaaggc cacttcgtca
     5641 tagccttcaa atctggcatc gaaatggaaa tatgaaaacc agaagtaaat agcccatgac
     5701 tctacagtag agttgtgggt tttcttttgc ttgctgatta taataatatt ttaataacta
     5761 ttgtgtttat caaccaaatg gtttataata ttcttagcgt aaacttggag gtgctgtatg
     5821 actacggcag aaatgattaa agaactgtgt gagcaaatga atataagtgt ttccgaactt
     5881 gctagacgta ttggccagac tccacagaat ttcaataaaa aattacaacg agaaacagta
     5941 accttggatg agttgaaggc cattgctgat gtgctaggtg tcaagtttgt gcaggcattt
     6001 attttaccag atggagaaga aataaaaata tctaacgaat aaaggaggat gtttatatgg
     6061 taggtaatgt tattcaaata gtaacagaga aattatcatc tttgcctttt atagaaggca
     6121 tcgtattagg gggctcacgt gcaagaggca cccatacaga aaattctgat atagatatcg
     6181 gaatctatta caattcagac tcatttgacc tgacagcgat taatcaaatt gctacagagt
     6241 tggatgatga gaatagaaac aaccttgttg tacctcccgg agcgtggggt gattgggtta
     6301 atggcggtgg atggttagtt ataaacgggt gtcatgttga cttgatatta cgtgatataa
     6361 aacgggtgga acaaataatc aaagatacgg agcaaggaat tgttactgcc aattatcaga
     6421 ccgggcatcc ccatggttat ataagtgcta tgtatcgtgg agaattagcg attagtaaaa
     6481 tactatatgc taagaacgaa agcttatgcg aattaaaaaa gcaggcagaa atttacccta
     6541 ctgctctaaa gaaaagcttg atgaactttt ttatatttga agctgaattc tctttaatgt
     6601 ttgtaaaagc aaatgcgggg gcagaggata aatattatat tgcaggccat gtttttcgta
     6661 ttatttcatg cttaaatcaa gtactatttg catgtaataa tgcttattgc attaacgaaa
     6721 agaaagctat aaaactgctt gaaacttttg aatataaacc tgaaaaatat gccgaaagag
     6781 ttaatcatat ttttgaagta ctcggtcttt ctctttttga atgctacgac atgaccgaga
     6841 aactttataa agaagtgaat gaaattgtat cggagataaa taacttttta aacgaggaga
     6901 gttcagatga aagaaaacaa atatgatgat aatatatttt ttcaaaaata cagtcaaatg
     6961 agtcgctcgc agaaaggact ggctggtgcg ggagaatggg agactttgaa aaagatgcta
     7021 cctgatttta agggtaagcg tgtgcttgat ttaggatgcg gctatggatg gcactgtata
     7081 tatgcgatgg aaaacggtgc ttcctctgta gtaggtgttg atatttctca taaaatgctc
     7141 gaagtagcaa aaggaaaaac ccattttcca cagattgaat atgaatgctg tgccatagaa
     7201 gatgtggatt tcccagagga gagctttgat gtaatactaa gttcgcttgc gtttcattat
     7261 gtagcagact atgagaattt aataaaaaag atatatagga tgctgaaggc tggtggcaat
     7321 ttagttttta cagttgaaca tcctgttttt actgctcatg gaacacaaga ctggtattat
     7381 aacgaaaaag gagaaatact gcatttcccg gtggacaatt attattatga gggcaaacgg
     7441 acagctatgt ttttggaaga aaaggttaca aaatatcata gaacactgac cacatatcta
     7501 aatacactgc tttcaaatag ttttataata aatcagattg tggagccaca gccgccagag
     7561 aacatgatgg atattccggg gatggcggat gaaatgcgac gcccaatgat gctgattgta
     7621 tcggcaaaaa agaagatgta ataatataga aaaaataaac gaggagtatg taaatgagat
     7681 cagaaaaaga aatgatggat ttagtacttt ctttagcaga acaggatgaa cgtattcgaa
     7741 ttgtgaccct tgaggggtca cgcgcaaata ttaatatacc taaagatgaa tttcaggatt
     7801 atgatattac atattttgta agtgatatag aaccgtttat atctaatgat gactggctta
     7861 atcaatttgg gaatataata atgatgcaaa agccggagga tatggaatta ttcccacctg
     7921 aagaaaaggg attttcctat cttatgctat ttgatgatta caataaaatt gatcttacct
     7981 tattgccctt ggaagagtta gataattacc taaagggcga taaattaata aaggttctaa
     8041 ttgataaaga ttgtagaatt aaaagggaca tagttccgac tgatatagat tatcatgtaa
     8101 gaaagccaag cgcaagggag tatgatgatt gctgcaatga attttggaat gtaacacctt
     8161 atgttattaa aggattgtgc cgtaaggaaa ttttatttgc tattgatcat tttaatcaga
     8221 ttgttcgcca tgagctgctg agaatgatat catggaaggt cggcatcgaa acaggcttta
     8281 aattaagtgt aggcaagaac tataagttta ttgaaaggta tatatccgag gatttgtggg
     8341 agaaactttt gtccacctac cggatggatt cctatgaaaa catatgggaa gcattatttc
     8401 tatgccatca attgttcagg gcggtatccg gtgaggtggc ggaaaggctt cattatgcct
     8461 atccggagta tgataggaat ataacaaaat ataccaggga catgtataaa aaatacactg
     8521 gtaaaaccgg ctgcctggat agcacatatg ccgctgatat agaagagagg cgggaacagt
     8581 gattacagaa atgaaagcag ggcacctgaa agatatcgat aaacccagcg aaccatttga
     8641 ggtgataggt aagattatac cgaggtatga aaacgagaat tggaccttta cagaattact
     8701 ctatgaagcg ccatatttaa aaagctacca agacgaagag gatgaagagg atgaggaggc
     8761 agattgcctt gaatatattg acaatactga taagataata tatctttact accaagacga
     8821 taaatgcgtc ggaaaagtta aactgcgaaa aaattggaac cggtacgctt atatagaaga
     8881 tatcgccgta tgtaaggatt tcagggggca aggcataggc agcgcgctta tcaatatatc
     8941 tatagaatgg gcaaagcata aaaacttgca tggactaatg cttgaaaccc aggacaataa
     9001 ccttatagct tgtaaattct atcataattg tggtttcaaa atcggctccg tcgatactat
     9061 gttatacgcc aactttgaaa acaactttga aaaagctgtt ttctggtatt taaggtttta
     9121 gaatgcaagg aacagtgaat tggagttcgt cttgttataa ttagcttctt ggggtatctt
     9181 taaatactgt agaaaagagg aaggaaataa taaatggcta aaatgagaat atcaccggaa
     9241 ttgaaaaaac tgatcgaaaa ataccgctgc gtaaaagata cggaaggaat gtctcctgct
     9301 aaggtatata agctggtggg agaaaatgaa aacctatatt taaaaatgac ggacagccgg
     9361 tataaaggga ccacctatga tgtggaacgg gaaaaggaca tgatgctatg gctggaagga
     9421 aagctgcctg ttccaaaggt cctgcacttt gaacggcatg atggctggag caatctgctc
     9481 atgagtgagg ccgatggcgt cctttgctcg gaagagtatg aagatgaaca aagccctgaa
     9541 aagattatcg agctgtatgc ggagtgcatc aggctctttc actccatcga catatcggat
     9601 tgtccctata cgaatagctt agacagccgc ttagccgaat tggattactt actgaataac
     9661 gatctggccg atgtggattg cgaaaactgg gaagaagaca ctccatttaa agatccgcgc
     9721 gagctgtatg attttttaaa gacggaaaag cccgaagagg aacttgtctt ttcccacggc
     9781 gacctgggag acagcaacat ctttgtgaaa gatggcaaag taagtggctt tattgatctt
     9841 gggagaagcg gcagggcgga caagtggtat gacattgcct tctgcgtccg gtcgatcagg
     9901 gaggatatcg gggaagaaca gtatgtcgag ctattttttg acttactggg gatcaagcct
     9961 gattgggaga aaataaaata ttatatttta ctggatgaat tgttttagta cctagattta
    10021 gatgtctaaa aagctttaac tacaagcttt ttagacatct aatcttttct gaagtacatc
    10081 cgcaactgtc catactctga tgttttatat cttttctaaa agttcgctag atagagttct
    10141 atattagaga tgtaaagagt tttggtgaag aggtttgtga gtatggcttt tataaccagg
    10201 gtgcaatgag aagcactaac agcagctagc ttaagaacgc ataggatata ctttttatgg
    10261 aagtcacaga ggaggaataa aatttgaaca ggattaacag agtaacctct attcttattc
    10321 agctgcaatc aaaaaaaata attcctgcca aagaaattgc acagcgattt aatataagct
    10381 taaggacagt ttacagagat atccggacac ttgaagaagc cggaatacca attggatctg
    10441 aggccggaaa aggatatttt cttgtagagg gcttcctact tccgccggta atgtttacag
    10501 cggcggaagt gggtgcattg attacagcag ggaaattttt aaattgccat ggagatgaat
    10561 catttataaa ggattttgat tcagctatgt ataaaatcaa atctattttg aagcatggtg
    10621 aaaaaaacta tgcacaggag ttggagaaca gtattaacgt gtacagcaca tctggacaga
    10681 aaaatacatt ggcggataac gttattgcag caattcagac tgcaatctgc aataaaaggg
    10741 taatatcaat tcaatatcct gcatcaggag ggcaagaacc ggaaagcaga atgatagagc
    10801 ctatatcact ggggttttat gaacagaact ggtacttaat cggttttgca ggctaagaaa
    10861 tgaatatagg aattttcgtg tggatcggat taaaagcatt tgcatagaag aagagctctg
    10921 tcaaagccat gatggctctt tggaacaaat attaaaacaa atgctttcat ataaaaaact
    10981 atatgcccta caatgccgtt gtaaaaattg gggaaaaggg atatattgat tttatatctt
    11041 tctcaaaata aatataaaag cccttt
//
LOCUS       DACBYO010000096        10941 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.096, whole genome shotgun sequence.
ACCESSION   DACBYO010000096 DACBYO010000000
VERSION     DACBYO010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.096"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(274..1257)
                     /locus_tag="IVD26_002436"
     CDS             complement(274..1257)
                     /locus_tag="IVD26_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAP6080360.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(1673..2443)
                     /locus_tag="IVD26_002437"
     CDS             complement(1673..2443)
                     /locus_tag="IVD26_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6080361.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(2436..3371)
                     /locus_tag="IVD26_002438"
     CDS             complement(2436..3371)
                     /locus_tag="IVD26_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6080362.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(3965..5614)
                     /locus_tag="IVD26_002439"
     CDS             complement(3965..5614)
                     /locus_tag="IVD26_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP6080363.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(5809..6705)
                     /locus_tag="IVD26_002440"
     CDS             complement(5809..6705)
                     /locus_tag="IVD26_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6080364.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(6698..7378)
                     /locus_tag="IVD26_002441"
     CDS             complement(6698..7378)
                     /locus_tag="IVD26_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6080365.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(7379..8161)
                     /locus_tag="IVD26_002442"
     CDS             complement(7379..8161)
                     /locus_tag="IVD26_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP6080366.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(8154..9071)
                     /locus_tag="IVD26_002443"
     CDS             complement(8154..9071)
                     /locus_tag="IVD26_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6080367.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(9074..9358)
                     /locus_tag="IVD26_002444"
     CDS             complement(9074..9358)
                     /locus_tag="IVD26_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6080368.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(10059..10679)
                     /locus_tag="IVD26_002445"
     CDS             complement(10059..10679)
                     /locus_tag="IVD26_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080369.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
BASE COUNT         3270 a         2349 c         1856 g         3466 t
ORIGIN      
        1 acctcttata aacggtgttc tcctaccaac tcttcggtca caagtcaaaa tattcatcaa
       61 acatgagaag ctgttttttg aaattgctcc ttgtgactca gagttaaacg gcaggctcac
      121 aacctctgat ataaacggtg ttcaatcaac tgaccctcgg tattagctca aaaaacgaca
      181 aaatatgaag agctattttt gtttggctgt tcttattact tgatacagga cagctttttc
      241 acgacctcta attcacggtg ttcaagcaag aaatcattgt tcactgaaaa gcgttggatg
      301 ttctttttca aaggtctcta agatctctcg tacttcatca gtagatttcg tattcatcaa
      361 ctgaactcgc aagtcatttg ctcctggaaa tcctttgata tagattttaa agaaacgatg
      421 tagtcctgtg atggaacgcg ggatgatttc tgaataatga tcttgcagat ctagttgcag
      481 acgaagtagt ccgatcagtt ctttttctgt atgttccctc gggtcttttt caaatgcata
      541 aggattcttg aaaatccctc ggccaatcat gatgccatca acgccatatt tctcggccaa
      601 ttcttctcct gtctggcgat cggggatatc tccattgatc gtgattagtg tttgtggagc
      661 gatttggtca cgtaaagcaa tgattttagg aatgacttcc caatgtgcat ctactttact
      721 catctcttta cgcgtacgca aatggacaga aagattggct atatcttgat gaagtaggtg
      781 actgatccat tcttccatct cagacatttc cgtatagccg atacgcgtct tgacgctgac
      841 aggcaaaccg ccagctttag ctgcttcaat caattgtgcc gctacttctg gacgaaggat
      901 caagccactg ccttttccac gttctgctac attagggact gggcagccca tgttgatatc
      961 gattccttgg aagcccattt ctgccatagc aatgctcatt tctctaaaaa attctggctt
     1021 gtctccccaa atatgggcaa ccatcggctg ttcatcttct gtaaatgtta atcttcctcg
     1081 tacactgtct tttccatctg gatgacagaa actgtctgag tttgtaaact cagtaaagaa
     1141 gacatccggt gctgctgcat gctttacgac atggcgaaat acaacatctg ttacatcttc
     1201 cattggtgct aaaacaaaaa aaggctttgg cagctctttc caaaaattag tagtcattta
     1261 tttgttactc tccattctat caagcagtga agtcgcaatc tttctcaaaa acattgtcat
     1321 tatactagga aacaaaaaaa gaagcaaagt gaacagctta aaagatgttt ctgattgagc
     1381 aaaaaaaaga ctgtgacaaa aatcttatca cagtccattt tccggaataa atggtgttca
     1441 aaagcttgca tctgcggtaa taagtccaac caaacgaaaa ataggaggag ctatttttgt
     1501 ttggctgttc ttattacttg atgcagaaca gctttttcac aacctctcca ctaaacggtg
     1561 ttcaatcagc tgaccctcgg tattcgctca aaaaacaaca aaatatgagg aactattttc
     1621 ccgtttgttt ctctaatact caggtcaaaa cgctgatttc acaacctctt ttctaacttc
     1681 tcaatcctct tcctttattg atcaaatacc aagtaacggc gtacaaaaca acgatgaata
     1741 acacaagtac gatcatcgat gttgctactg gcacatcgat cgttccaagg aatccgtaac
     1801 ggaaaccgga gatcatataa acgatcggat tgacttttga aacagcttgc caaaagggcg
     1861 gtaacataga gatggcatag aaaacgccac ctagataagt taacggctgc aagacaaatg
     1921 taggcacgat cgatacatca tcataagact gagcaaaaat cccgttgagc agtcctgcta
     1981 atgaaaacaa gattgccgtc atcaataatg taatgatgac catgaaccat gaatacacat
     2041 gaagtggtac aaagaacaag gaaatgatcg ttacgagaga gccgacgaga atactgcgac
     2101 ccacaccacc aatcacaaag ccccaaataa tcacatgcgt aggaacaggt gctaccaaga
     2161 tttcttcgat atttttctga aatttttgag agaagaagga cgaagaaaca ttggcatacg
     2221 aactagtgat agcagacatc ataatcaaac caggaacgat gaattccata tatgaaaaac
     2281 cacccatgtc accgatccgc ccaccgatca tttttccgaa aataacaaaa tacaaggatg
     2341 tcgtgatcac tggcggaacc agtgtttgga cccatatacg caaatagcgg ttcgtttcct
     2401 tgatagctaa actttttaat gcagtaaaat aaagattaaa catttttctc ctccgtatga
     2461 ttattttctt ctgtgatttt caagaacagt tcttctaaac gattcgactt attcctcata
     2521 gaaagaactt tgattccttg tcttgtaagc tgatcgaaga ttccgttcac cccttgattt
     2581 cgttcaactt cgacagcgat tgtctgctca tcttcaaatg tacaagcata tccttcaatc
     2641 acaggtttgg tatcatatgg cgctaaatca aagataaatg tttcaaattg cagttttgac
     2701 agaagctctt tcatacttgt attctcgatc agttcacccg attggatgat tccgatgttg
     2761 cgacaaagca tttcagcttc ttctagataa tgcgtcgtca aaatgatcgt tgtaccattt
     2821 tcgttcaatt ctcgtagaaa ctcccacatc tcgcgtctca actcgatgtc aactcctgct
     2881 gttggttcat ccaagatcag caaacgtggt tcatgcatca atgccctagc aatcatcagt
     2941 cttcgcttca ttcccccgga aagcatacgt gcacggacat ttctcttttc ccaaagattg
     3001 gactgcttca aatatttttc gctgcgtttc atcgcttctt tgcgagagac accgtagtag
     3061 cctgcttgat tcacgacgat ttgctggacc gtttcaaaag ggttaaaatt gaactcttgt
     3121 ggaaccaatc caatctgttg ctttgctcga actagatcct tgtccagatc ataaccgaag
     3181 acattcactt ttccagatgt tttattgact aaagaagtaa taatcccgat cgttgtagac
     3241 ttcccagctc catttggccc taatagcgca tagaaatctc cttctttcac cgaaagatcg
     3301 attccccgca atgcttcgac cccacttcca tagatctttt tcaaattatt tatttcaagc
     3361 gcatttgcca tttatttcct atctccttat agacatgatt cttaattgta tcatggaata
     3421 cagcagatga aaaaacaact tggcttccac acaaaaacac acctgctaac aaagaggaga
     3481 tgtgttttct agttcatgat catcttcgat agaataacta tctaaacaac tctggaactt
     3541 ttaaaatcat aaaagtaccg acagcaacta ctacgatgac atatagaaga tccttataac
     3601 tgaggttctt gtctttttta ttcatgttaa gctttcctcc gtccttttat cgaaagcttt
     3661 tttcttttat tttaaccgaa ataaataaaa tggaaatagt tattttcaat ttctgttttc
     3721 gctgtttgtt ttacggagaa ctttgccatg gaacgtgcgt ctcgtcgctg atgctaagtt
     3781 ttttcgataa aagctgctag aaggaagaca gcgtggttta ttttgtatcg tcttttgcta
     3841 aatcttccaa gatcatctgg acagcagact cgttcccatt gaattctgcc acttttttgg
     3901 catcaatgta cttcttttga taatcgtctt tttggaccca cgcatcatgc ttcgtttgat
     3961 aaagttaatc aaacggatac cactgacgct gttcatcgaa caacaaactt tctttttggg
     4021 cctgttcaac tatggattta ggataattca aaactttcag caaggcaatc gcatttcggg
     4081 tccttgaagg tccttctttt aatttgaaat caaaactgat tccttttcct tctgttactt
     4141 gttcttcaaa gtggacattc tcacaataat tctttaaaat ctctgtcaat tcgatatcat
     4201 gtgtggcgac aaatgctaaa gatggatact ccgcaagcca ccgaacgact gaagcggaag
     4261 aagcaatccg ttcgatcgta tttgttcctt ttaaaatctc atctacgaag cagtagcagc
     4321 gttctttgga agccacttgg tccagcaaac gtttgatcga tttgatttct gaaacaaaat
     4381 aactgtcgcc ttcaaataaa tcatcttcga ttgccatgga agtcaacaca tgtccaggtt
     4441 gcagggtaaa ctgttctgca atcgctgttt ggatcgtctg tgctagaata cagctgatgg
     4501 ctatactttt gacatacgta gattttcctg atgcattgga acccgtgact aatgtattct
     4561 tctgccagtt gactggatta actaccgctt cttttaacaa tggatgatag atatctttcg
     4621 ctgtcacacc gccctcagta aactctggtc ggcaagtgat cggcatatag gtgcgataat
     4681 tcaaaacggc tgctgcaact tccaattctc ccagcaattc ccacagcttg atggcttcag
     4741 ttgaatgctt ttctaattta gtgagaacga aatgatagga gataaatggc agcatgaaca
     4801 tgatgttgac atattcaaaa atcaattctg cttcactccc gctcttcatt cgaaatgaaa
     4861 aacctaattt agggatgtct cttaatggtt tagtttgctg tttcagctct ttttgaagtg
     4921 gtgtcgtcat ttttgctaac tgattggcgg ctgaaatcgt tgaaaccaaa taactcatgc
     4981 tattcagctc tgtttctagt gtttgtttct tcactagata atagaccgta ttgaatacta
     5041 agccaccgat tgctagatag attcctagta cttgccctaa aagaagcaaa cctacaccca
     5101 ccagcggaag caagccaaga aaaataaata aacctacgcg tccaatcttt ttactttttc
     5161 catccgctag atattgtttt gcaaaattat gatctttttt tcctaaacga gcgaattgat
     5221 attggattct ttctctcagt tgaggatttt cctgataaaa agcaattagt ttttctaact
     5281 gataatcttc tccaaaatca aagctacgta aacgctgata caacgcttct gaacctacac
     5341 tagaataggt actgttgatc ccttcaaata cttcgaacat atccaagtca taccaagtaa
     5401 gatcgtcgat ttcactatcc catgaacgga attttttctc cgtgagccac gcatccttca
     5461 aactttcttc tttatcaaat ctcggttgat aaggaatttt tccccaatta ctacgaactg
     5521 tttcctttac tttcaaacgt gaaaaaatgt ctaaaacaac taataaaata acaactgcaa
     5581 taataattaa aacgataaat tctctttggc ccatatccct ctccgttcct tgatttgtta
     5641 gttttagtat agcactgttg cgctatttga aaagggggta caaaaataac tgtcttcgtt
     5701 acctaattcg tatcaatcac accaaaataa aaacaccttc caaaaaagaa gatgtcttta
     5761 aaacgagata caattttttg tcattcactt caggtaaatt agagccaatt aaaccctccg
     5821 caacttgacg gagatggaga agatgccccc gtctaatcta gcggtcatct ctcctcccat
     5881 tccttccacc aatttttttg acaggtaaag cccgattccg ctagattccg tatttgtgcg
     5941 gctggtattt tcggtataaa aacgctggaa gactttttca acagaggttt gcgctcctgg
     6001 tttgatagga ttggccactg ttaatcgaat gaatgaatcc tcttttgaaa atgtcacctt
     6061 tgcttgtcca tctgcataac gcaataaatt ctgtatgata ttttgcagca ctcgcagcaa
     6121 catgagcgga tctgctaata cagttgtatt tatcgagtgt tcagcgaacg ctacctcgat
     6181 atttttctca gaaaattgtt cataaaaaga gaaaaatact tcttccacct ctttagaaaa
     6241 agaaagcgta tggagatcca tttctttttg cttcgtctct attcgagcaa gatcataaaa
     6301 ctgatccgtc atactgagta atcttgcaac agattgtttg atgatcgtta aatacttctc
     6361 ccgtttctcc gtatcctcta cctgttccag taattgtaca taaccgttaa tagcagtcaa
     6421 aggagttctg agatcatgag aaaggccgac gatcgatagt ctgatgtttt cttccatttc
     6481 ttgaaatgct tgtccttttt gttcattttc atccacccat gtattcagtg catctactag
     6541 gtccattaga ttcttttctc gaaattcgac tgaaagacga ccaccatatt cttgtcgttc
     6601 agaaagagtg gcgattttct tagttaatct cttgatttcc ctttgcagga agaaaataaa
     6661 acttcccata aagataacaa cgagaagcaa cagccactta atcaaatcta aaccccactc
     6721 cccacaccgt atgaatatac acagcatgtg cctttgctag tttccctcga agattggaaa
     6781 tatgcatatt cactgttttc tcactatcaa aatatggttc ttgccaaact gtttcataaa
     6841 gatttgctcg cgaaaatact tttttcggat gttctaaaaa aagcttcagc agatcgaatt
     6901 ctcttcctgt caaatggaca gccacaccat tcacatttac atccctcgac tctttgtcca
     6961 gtaagatttc cttgtaatag atgcgttgcg acagatcttt tacttggaca gaagtctgat
     7021 gacgaagttg gatgccgatt cgtaacaaca gttcttcgat atcaaatggt ttcgtcacat
     7081 agtcatccgc tcctgctgcc aacaaggaaa ctttatctct ttgatcgctt tttgctgaaa
     7141 gaacgatgat cggaacattc gatgtctgtc ggatttctgc taacaatgct tcacctgaaa
     7201 gccctggaag catgagatct agaaggatca aatcgacagg atatgtgctt aacaataatt
     7261 ttccttccgt acctgaataa gcatcaagaa gtttgtatct ctgttcaaga acctcctcca
     7321 gtaaagaatg aacagcttca tcgtcttcga taatcaaaat agtttccagc aggaacacct
     7381 acttaatgtc agatttttgg aaaataaaca ttcctagagc tgatgatacc acgattgtta
     7441 ctagactgac cagaatcatt ttcggtgctt gcgaataagt tgcttgttgc gcaaagtccg
     7501 tatacatgag ccacgtttcc gtaaaccact ccgttagaaa ttccaagcct ttgatttttg
     7561 cgaaaacacc gggaacgaag gccgttccca tgatataaag aaaagaaaga agcaaactga
     7621 cactggtact tctagtgatg aatgtcaaag ccactggaac agataatgtc gctaatatca
     7681 gcagaagcaa tacaggaaat acttttagaa cataatttcc atagtttttg attccctcaa
     7741 cttcaccaaa tccgaaagca agtgtgtaag caatcatggc tagccccgta atcaaaacca
     7801 cgccaagtgt tgtgatcaaa agcgtaacga gaagtttcga cacataataa gtcattcgat
     7861 tccgtcctaa agataacgta ttgcgaatcg taccgttttg aaattcttcc ccaatataaa
     7921 agcacgcaaa tgctgcgaaa gccagaagaa tccatgcagc cattttttcc accattaaaa
     7981 tccctgttgc accgttgatg actgtatccg ttgcttggtt taattcattg ccgtattttg
     8041 tatgcatata ccattcgttc caagaataaa aaagcggaag tacgaccatc agtcctagtg
     8101 agacccacat tttacggctc ttccatactt ttattttttc agcagttaat agattaaaca
     8161 tgtggattgc ctccagttaa ttgtaagaaa taatcttcca gtttttgccc aactaggtgg
     8221 ataccatcca caggaacttt tgcctctacc aatgcttgat tgatggctgc tacttggtca
     8281 attccttcaa aaagctggat aacacggcta gattggacaa aataatccct ataaccaaga
     8341 gagtcgagaa ccgttactgc ttgttccgtc gccgaagtgt caatttttat aaattgacga
     8401 gattcttgtg ccaattcttc tttcgataat tctttgatca agtgtccttc atgcaaaata
     8461 ccgtagtgag tggcgatctg tgacaattca tctagcaagt ggctagaaag caagacggtg
     8521 atgccccgtt cttttaccaa acgttggatg atttctcgca tttctgccat ccctgctgga
     8581 tccatcccat tcgtcggttc atccaaaatc aaaaattctg gattcgtgat cagtgcattt
     8641 gcaatagcta aacgctggcg catacctaaa gagaaattct ttgctttctt tttccctgta
     8701 ttttccaatc gcatcatttt cagcaggtct tcgatttctc tatccgacac accgccgttc
     8761 gctgcttgga tacgtaggtt atctcttgca gttaattctg gataaagagc aggggtttca
     8821 atcgattgac ccatacgtcg tcttgctgcc tgcaaatccg tcgttccaaa taattcgatc
     8881 gaaccttcat caatcgagat caaacccata atagttctca taaaggtaga cttacccgct
     8941 ccattctccc caatcaaacc atagatcatt ccacgtttga tttcgatcga tactttatct
     9001 aatgctttgg cagcaccgta ttttttggtt ataccagttg ctttcaagac cgtttcattt
     9061 ccaaaatcca tacttatcct tctttcttat tgataagtga agtatagttg acgggtataa
     9121 agaaagcagc cagaaatgta taaagaaagt gtaaattttc caattgaatt tcaagaaaaa
     9181 tcagactgtc tcgcagacgt ggttgagttg tctgccaatc aaagagcgca ccaaacagtg
     9241 ctaatccaag tggactggcc accatggtaa tcgttgttat cgttgacatc agacgtcctt
     9301 gtatatgcgt tggaacttct cgctgaagcc agaccatata aaaagcaaaa gaaaacatta
     9361 atccttaaaa acggacttat gaaaaataat acatgccgtt tgggatttac aattagctac
     9421 caaataagag gttatgacaa aagacttttc acaatccctt cttccgaata aacggtgttc
     9481 tcctgccaac tcctcggtca caagtcacaa tatttatcaa acatgagaag caatttttgt
     9541 aaattccttc ttatttcttg aagctgacca cttctgtcac aacctcagaa gcggataaat
     9601 aatattgttt gatgatactt tatctttttc ccgtttgttt atagatcgaa tgatattata
     9661 gaccaagaat cctacctatt aacatagcta aaaacacaaa aaaggcactt tccaaattgt
     9721 ggaaagtgcc agaaaagtta ggattaaggt aactgcgctc agcattgctt cgcccagtac
     9781 gattctcgta actcgtgaac tcgaacgata atcgcaatta acgttttgag aactgtgaag
     9841 ctttacgggc tttcttaaga cctggttaaa caaaactcta ttttattgca ttttacagga
     9901 atgtatttca tgcgaaatta ataagtcttt gtttatagag ttttactagg gtataaaaag
     9961 ttgtatgtta tcattacctc aaaacattac ctcagcttgg cgagttggtt gattgaagaa
    10021 taaatcattt atctagatat ctcaataaaa aatgatttct aagaaacttg tattttcgtg
    10081 ttattatttt tttgccctat caaaatttct aattcttcta gcgtaatatg attatgacac
    10141 ataatcgatt caattacttc aatacctatt tttttcgaga aagatccctt ttgttcactc
    10201 acaaaaatac tttcagaaga catatataag gaacgaagtt ttggaattag tatatcgtac
    10261 aaatagacca ccataaaatc gtccttgcaa ccattctcaa aaagaattaa atttgctgat
    10321 tgtgttacat atatcactga attacattca tggtcaattc caaaaacaat gtctacttca
    10381 ttttcttttc taattcgcgc agttacattt ttcaaacttt caccattact tataaatgct
    10441 ttagttactg taagctctga tgtttgttca gatattcctt ttataatatt ttgttcatca
    10501 gccacattcc ccataaatcc gccgattcct tttaagtaat aattctcacc taagagtcgc
    10561 ttgcattcac tgaattgata aaaaaaccag ttaaaaaaat cttctggaaa aataaattct
    10621 gatcgaactt tatttatatt tttagctcct attaatttta taactcgatt aatgttcact
    10681 tgctgcgatg aacatataac tgaataaatt gagttgttta attcaaaaaa acaactttaa
    10741 catatgcatc attaattcgt tattttttag gtagatattg atcattgtta tctctctttt
    10801 tttgcttccc atactccaac ttagaaattg ccgttataaa atttatttta aaggtgactt
    10861 tttcccctga agtatcggta gtaggaatac ttaatacctc agcttctgag gaggtatccc
    10921 aattatagtt atactttgca t
//
LOCUS       DACBYO010000097        10690 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.097, whole genome shotgun sequence.
ACCESSION   DACBYO010000097 DACBYO010000000
VERSION     DACBYO010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.097"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..808
                     /locus_tag="IVD26_002446"
     CDS             <1..808
                     /locus_tag="IVD26_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP6080370.1"
                     /translation="VLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLECY
                     FSRFSLATREAVQWIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKE
                     TTARLKGTSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIVDRLL
                     SACPNLRQGYQLYQDILYAVKKRDQSLFEDCLNREVSGLPETYTTTLRTFKKFLPQIQ
                     NALHYSYSNGPLECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGKTFLTK"
     gene            928..1128
                     /locus_tag="IVD26_002447"
     CDS             928..1128
                     /locus_tag="IVD26_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6080371.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            1204..1401
                     /locus_tag="IVD26_002448"
     CDS             1204..1401
                     /locus_tag="IVD26_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080372.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(1698..3245)
                     /locus_tag="IVD26_002449"
     CDS             complement(1698..3245)
                     /locus_tag="IVD26_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAP6080373.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(3329..4132)
                     /locus_tag="IVD26_002450"
     CDS             complement(3329..4132)
                     /locus_tag="IVD26_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAP6080374.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            complement(4135..4917)
                     /gene="phnE"
                     /locus_tag="IVD26_002451"
     CDS             complement(4135..4917)
                     /gene="phnE"
                     /locus_tag="IVD26_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAP6080375.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            complement(4914..5693)
                     /gene="phnE"
                     /locus_tag="IVD26_002452"
     CDS             complement(4914..5693)
                     /gene="phnE"
                     /locus_tag="IVD26_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAP6080376.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            complement(5665..6456)
                     /gene="phnC"
                     /locus_tag="IVD26_002453"
     CDS             complement(5665..6456)
                     /gene="phnC"
                     /locus_tag="IVD26_002453"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HAP6080377.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            complement(6517..7446)
                     /locus_tag="IVD26_002454"
     CDS             complement(6517..7446)
                     /locus_tag="IVD26_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HAP6080378.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            7641..8324
                     /locus_tag="IVD26_002455"
     CDS             7641..8324
                     /locus_tag="IVD26_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HAP6080379.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            8485..9528
                     /locus_tag="IVD26_002456"
     CDS             8485..9528
                     /locus_tag="IVD26_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP6080380.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
     gene            9592..>10690
                     /locus_tag="IVD26_002457"
     CDS             9592..>10690
                     /locus_tag="IVD26_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HAP6080381.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGEREKQFAYSAHTSCDDNGFILSTIITPGNIYDSQVAFQLVKQSKRLFPEIN
                     CVVADAGYKTPKFVHFLTHLNLRPCLPYSRPKGKKGLLSKNEFLYDEYFDCYICPQDQ
                     MLAFSTVTREGYREYKSNPKECVNCPLLNQCT"
BASE COUNT         3288 a         2166 c         2121 g         3115 t
ORIGIN      
        1 ggtcttatgc tttgatgaat tcaaatcggt tcgaagtgtt gccagtgcaa tgagttttat
       61 catgatggac ggacaaagcc atgcattatt ggatattgtc gaaaatcgac gcttgcctta
      121 tttagaatgc tatttttctc ggttttcatt agcgactcgt gaagccgttc aatggattgt
      181 tattgatatg tatgcgcctt atgtttcatt ggtgaaaaag cttttcccga atgctcagtt
      241 gatcatcgac cgtttccaca tcgtccaaca tattggcaga accttcttga atcatcgagt
      301 gaaagaaacc acggcacggc ttaaaggaac ttcccactct caacgagggt tagggaaaaa
      361 attgaaacgc tattggaaac tcctacaaaa agaagaagca aagttaaact acgaaaaaag
      421 ggtttggcgt gccagtttta aagattattt gactgaaagt gagattgtcg atcgactgtt
      481 atctgcttgt cccaacctgc gccaaggcta tcagttatac caagacattc tttatgcggt
      541 aaagaaaaga gatcagtcat tatttgagga ctgtttaaac agagaagtca gcggtcttcc
      601 tgaaacctat acaaccactt tacgaacgtt taaaaagttt ctgccacaga tccaaaatgc
      661 gcttcactac agctattcaa atggaccatt ggaatgttta aacaaccaca tcaaagtatt
      721 aaaacgcaat gcgtacggct ttcgcagctt ttacaatttc aaactacgga tcatgattcg
      781 tcatggcaaa acatttttaa ccaaataaac agaacagaaa gagagtttct tctttctgtt
      841 ctgtccaaat tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctgtattt
      901 attactgtcg aggacaatgg catcggcatg attgaagagg aacaaaaaaa catttgggat
      961 cgctattata aagccgatcc gtcaagtaaa aatacaaaga taggcgagtc aggtcttgga
     1021 ttatcaatcg tgaaggaact agtgcgcctg caccacggtt caattgaagt gaccagccga
     1081 aaaaatgaag gaacgacctt cctgatacaa tttccaaaag aaaaataaaa ttaccagtaa
     1141 aaaaccgtgg agagatagct gctattgatt tttgctatgt cttttctttg agaggtatcc
     1201 ggtatggtgg agtgtctgaa aaataaaaaa atggaggcca attttgtgaa agctgttatt
     1261 tctggaagta ttgttttcca agaagaatat cgagatatgg aaaaagattt cagtaaaaaa
     1321 ggcattgaat taattgatta tcctcgctca tgtccgatcc tagacaaaga gtatccagaa
     1381 atcttgacga ctttttttta aatatcgcag cagcggattt attttttgta tttaatcaag
     1441 atcggaaagg ggtattaggc tatattggtg ccgcaacttt ttcagaaatg aagtattgtc
     1501 tgatgcaaaa tcttattcat ggaaaaagga tcaaaatagt cttatttaag gaaccatcag
     1561 aggaaaattt tttgttttga tgaggtagat cgctggctaa agaatggctg gatggaaatc
     1621 agacagccta acaatttggc ataacaaagg tgtgggcaaa aaactgctca cacctttttg
     1681 aattttttat ttatatacta caaaatcact tgaaaattat gattcacttt tgcttcgatg
     1741 cgtgggtgaa tattcaaata gtcggcaatt aattcggtca tgtcgatttg gatttctcgg
     1801 acaattttct ccgcaccaaa catcgcataa tttcctccgc cgattgcccg atattgattt
     1861 gtcaccactt ccagcatttg ttgcggaaga acggggtgac ctttaaaacg aagttcggta
     1921 atccgttgtc caacaggctg tttcatatca atagtgtact gaatcccttc atacatgtca
     1981 taattgtagt actggggctt aggctgaata aaggctggat tgaatacgat ttggttattt
     2041 tctacagcta aataatttgc ggtctgctcc aacgccgctc tcaaatctgc accatttatt
     2101 tgaatcactg ccagagtatt cggataaata tagttggtga tgacgtcccg catcgtgatc
     2161 gtctcaccaa agccttttcc ttcattattg aataacgcag ttccagaaat ctctgagccg
     2221 ctggcaaata attgtacacg attaataaac tctacatagg gatgttcctc aagacgagcc
     2281 tgcatcggat cattaatacg catatttccg ttcactttac ctaagggttg atccaaccat
     2341 ttctctagtt tttcttctac cggtacgatc gctgcaagaa tttctggatc aggctctgat
     2401 ttttcaactg agtgtaaagc aacctggtga tctgtaacaa ccacttgccc ctcttttttc
     2461 tcgacggtaa gacgaatttc accgatgaac tcgccacgat agcctggttg aacaacggga
     2521 actccatgaa ccgtttcagc aattttccgg tgctgatgac cggtgaaaag ggcgtcaatg
     2581 ccttcaacct gctgcaatag ctcgtagcct tcattctctc cagttagcgc ttctgtgtcc
     2641 tcaccggtta acaagtcttt ttcaaatccg ccgtggtaac taacgattac caagtctgct
     2701 tgtttcctta atagaggaac atattctttt gctgtttcga cgatactctt aaacgtaatt
     2761 cctgctaagg tttctggctt ttcccagtga ggaatgtatt gtgtcgttaa tcccaagata
     2821 gcaattttta cacccacctt ttcgataatc ttataggcgt ttccaaagta tggttggtca
     2881 tttttgttca ccatattggc tcctaatata ggcgcttgat aattcttaat cgcttcctcg
     2941 agataatcca caccatagtt aaactcatga tttcccaaca cttgaacatc atagctcatt
     3001 tggttaatca agtctgtaag ctctttggct gaaccatatt ctttagcaag ataataactc
     3061 aaaggagacc cttggatgaa atcaccattt tcgatcgtaa ttaccggtcc atctgctttt
     3121 gcccgtaatt ccttcagttt cgacgatact ttagccgttc ctaaggccag atcggttctg
     3181 ccggaatagt ctgttggtga aacatagcca tgcatatcac ttgtctctaa aaacgtaatg
     3241 ttcattctgc gtgctccttt agctgactca aaatagaaaa accgaagcgt attcagctgt
     3301 tcggtctctt tttttgattt ataatgcctt aatccttcat ttgaagtgtt tttaaaatgt
     3361 tgcctggaat aaagttttct gttgtctggc gaacaatcct tccttgatcg agatgataaa
     3421 ggttataccc atgacgttct tcaaagcgta cgaagccatc gccttcatct tcaccaacaa
     3481 aggacatact cgatacagta aaatagggga tcccattaat ttcatcagta aatgtgtgat
     3541 gggtatgacc gtttaggata cagcgaatat cgtaaggtgc gattagcttc aagaaacgtt
     3601 cggtaccagg ccattttggt atactgcttt ggtgagacag tagatgatga tgggtgacca
     3661 agaaaatcgg ttggtctttt tcttgctcta aggctttttt cagccattga aattgctgat
     3721 cgtccactat accatctgcg tatccatagc ttgaattatc aaaggaaatc actgtaaact
     3781 caggatattt gactatctgg ttgtacgggg cagaagaggc ggcttcatcg caccagccta
     3841 cccaaaaatg ttctttgata tcgtgattgc ctagagtaac aagaatcgtc gtttctccta
     3901 gcgcattttc cagccaagtc ttcaagtatc gataatcgtc tatttcgcca tcttcggtta
     3961 aatctccgct gataatcaca aggtccaagg gtgtttgctg caggagatga tgaatgcatt
     4021 gctccagagg gataagggga ttctgcatcg tagccagcat tcccttatag ccttcttcac
     4081 aagcctcata ctctctgcga aagtgtatat ctgatatatg caatatattc attcttatct
     4141 caatctcttt cttataattc cggttatttg atctaaaata aacacggtta cgactacgcc
     4201 aatcaaaata atactcactt tgctccaaga ccgagtttga atcgcgaata tcaatggagc
     4261 accgattccg ccagcgccaa ctaagcctaa ggtagccgca ctacgaaccg ctatttcaaa
     4321 atgatttaat gctaaagaac aataaatcgg catcaaatag gggatgcgaa caaagaaaat
     4381 cgtttgccaa aaatttgctc ctaccgcatg catttcttca acaagtcgct catccatcgc
     4441 ttccatttct tctgtaaaaa gtttgccaag cattccgatc tgatggacgc caatcgccat
     4501 aacaccagca aaggggccag gtccgacgac tttcacaaaa ataattgcaa aaactagttc
     4561 aggaaaagct cgtaaaacat tacagataag cttgccaatt tttgttaccc atggatgtgc
     4621 ttgccagagg ttaaccgcac tgatcaaggt aatgggaatc gctaataccg tagcgatcat
     4681 tgtccctaaa caggcgattc caatggttaa taatagcaaa ctaatcaaat cctcgccgct
     4741 gccatcatat agaaactgcc aatcaggctg acctaaccct ctcaaaacgt ccattcccat
     4801 ggaaggagag aaggtgctta atccagagta atccagagta gcggccgaca aaataacgag
     4861 aatcactaaa gcaactaatg ataaaagggt tcttctgttc atttcacgaa gcatcataac
     4921 agggacctcc tgacacgttc acttaattta tcaacgatcg cgacagttac taggatcgtt
     4981 agaataatga ttgaaactcg ttcataattc aaaagcgcaa gtgaggaatt tagaataacg
     5041 ccaataccac cagctccgac atatccaagg acagtagaag cacgaacatt cacctcaaac
     5101 gcgtaaaaag catagctcgc aaactgactc aaaacttgtg gagcgatcga ccaaatagcg
     5161 atttgcattt tatttgctcc aacagccgca gcggcttcaa tcgggccaaa gtcaatggtt
     5221 tcaattgctt gaaacattaa ttgtgacacc ataccaaaag taaagacagc gatagtcaac
     5281 acgccagtcg cttcaccaat tccaaacaca gcaacaaaaa gcgcggctaa aagcagggta
     5341 gggatggtcc gtactaaacc taaaagaaaa cgaaagatgg tagaaagaag acggttttct
     5401 gtcactacag tggtcgctaa aaaactaaca gggatcgcta aaattaagcc aatgaccgtt
     5461 ccaagcaaag acatttgaag tgttttcacc ataggctcga ctaatttagg taaatagcta
     5521 aagtctggat gaatgaagcg tgataaaaag acagtcattt gattggagtt ttgaaaaacc
     5581 tgagaaaaat cagctgacgt gatccaggca cttccttgaa aacaaacaat taagaacaga
     5641 agaataagca ggtgtttata ccatttaaag tgaacggttt ctttcaagct catcgatttc
     5701 gcctgccttt tcttcaaaga ttgcattgcc ataaatttgc tctaagcgtt catcggttaa
     5761 gtcgtctgga cgaccatcaa agacaacctg agcagctttt aacgcgagca cacgcgtaga
     5821 aaactcacga gccagaggga ctgaatgcag attgacaatg actgttttat ccatcgtttg
     5881 attgatattt tttaggtcca tcataacctt ttgagtcgtg attggatcta atgatgcaac
     5941 gggttcatcc gctaaaataa tgggggcttg ctgcacgagt gctcgcgcaa tggatactcg
     6001 ctgttgttgc ccaccactga gctcatcact gcgtgtctgc aatttatcag acaaaccaac
     6061 tttttccagt gcttcctttg tctgctggta gtcttccttc gtaaaaagac ctaaaatact
     6121 tttccaagtg gagtaatagc ccaaacgtcc agatagcaca tttttctgaa ccgtactacg
     6181 ctttaccaga ttgaagcttt gcgagattag accaatctgg cggcgaatct gtcgcagctc
     6241 ttttttattc gcttttgtaa tagaggttcc attaatgcga atatctcctt tggtggtttc
     6301 tgccaagcga ttgatactgc gcagcagagt gctctttcca gcaccactca accctatgat
     6361 ggaaacaaat tctccatctt caattgttaa gtcaatatcc ttcaagccaa caacgccatt
     6421 gggatagacc ttcgaaacat tgtcaaaaat aatcattatc cttctccatt tttttaagtg
     6481 taagcaaaaa aaagcttgct gacacttact gatgttttat tctgctgctt ttttcgtgta
     6541 gtctctgatc gtgtcatagg cagaatcagc agcttcttca tagccctgat gcccccacaa
     6601 agccattgct tctttgccat ctttatcatc cttcatattt aagaaggtct ctttaatttt
     6661 cgcttttaaa tcttttgaca tgtcaggctg tacagcgatt gcgtcattcg gaatatcgcc
     6721 ttttgtcagg tacaggactt ttaaatcctt aaataaatca ttatctggga aattcgaagc
     6781 aaaaacattt cgcgcgcctt caaaaacaaa cgccgcatcc atttgcttgt tcaacactgc
     6841 ggtaatctca ctcggaatat cattcacagt ggtcatcttt gtatctgcag taggatcaat
     6901 cccagcatct ttcaattcag cgacaggata gatgtagccg ctagcagagt taggacttaa
     6961 ggttgcgata ttttttcctt ttaaatcagt taacttattc aatccgctat cggcacgaac
     7021 caatacttct cctttaaagg tgttcgtaag tttgtccttt aatggcaagc cagtttcttg
     7081 atcataatcg ccgagctgag aagtcaggat tgcatctgca gctccagcat cctttgcttg
     7141 aacataggct gcaggcggca taattccgac atcgacttga ccagaagaca tcgcttcgac
     7201 gatcgttgaa taatcagtag ctaacgtcac ttctacctca cgatctaact ttttcgataa
     7261 atacttagca aatggttttg cttttgcctc catactacca tcattgtttg ttggaacgaa
     7321 ttgaacaact aatttttctt tgctctcttt ttctgagctg ctacttgtat tcccagaacc
     7381 gcaggccgcc aaagtggtca ataacatgac tccgatgaac ccttttgcta actgtttgaa
     7441 ctgcattttt ctcctcctgt tggatataat ttctaatacg tctaaatcat agcagggaat
     7501 caaaatcaat gaagtgacgc acgtcctatt ttacacaact tttacataca atttacaaac
     7561 aattataaat aattattcgt attgagccga aaaacaatct aagctataat aaagaaaaac
     7621 ttcttagagg tgacgatttc atgaaaaaaa tccatgatac gaagcaatta actgcttacg
     7681 ttgagaagca caacctgcag gattatatgg attcagatat attggcaatg gcttctttac
     7741 ttttttttga aaaggaagag cacctcattc aaacgggaaa aacctcagat tatttgtatt
     7801 ttttagtgga tgggacggta atggtgtact cgtattcttc tgatacacaa aatatttgca
     7861 tcgattacgc aaagcccgct acaccactcg gcgaagcctc ttcattgtgg gaattatcgc
     7921 cgaaaagcag cgttaaagca gtgactaagt gcatctgtat cagcattccg ctaaatcaat
     7981 atcgaacaca gcttcaaaaa gatgttcgct ttttgcagaa tatttgccag ttactaagtt
     8041 atcgtttaaa ttccgggata aatttggcga actcactgac agaacctgtt gaaactcgtt
     8101 tagcaaagtt tattttgacc catcacgaaa acgaacgttt ctcatttcgg ttaaccacct
     8161 gcgcctcaat cttaaatgtc agttatcgac atcttttacg aacaatcacg aattttcgtg
     8221 aggagaatat tatcgaaaag aaaaagaatt attacttgat tcatgatatc gaagctttag
     8281 aggacttagc tgagaatata agtagtccag taaaagcaga ataacagcta taaaaaaaca
     8341 gcagtcagaa gtgattgctg gttttttgat agtggagaaa ttgggaaacg gaaaatcttc
     8401 gttgaagagt agtgttctat atattggtat gctatacttt taaaagttca atgtgtcaag
     8461 acacataaaa aggggagaaa aattttgaag aaaatacttg tttcattgtt gtttttggtg
     8521 tcattagtaa cgttagtcgg ctgtagtcag tctcaggggg agaagcaaag tgaaaaagag
     8581 aaaagtaaaa tcgctttggt tcttggattt ggcggggttg atgaccgctc cttcaatcaa
     8641 gctggctggg aaggattaga ggcttgggga aaagagaaaa agctgacagc aaaaaaagat
     8701 tttacgtata tagaaacgaa caatccagag gataacagta ccaatatcga tcaggcaatc
     8761 agaaacggct ttaccaccat tattagcttg agctacttgc aagcagagga actggaaaat
     8821 gctgctaaag ataatccaaa gttgaaattt gccttggtag atggtgagat tactgggaaa
     8881 aagaatatct catcagcaac ctttaaagat caagaaagtg cgtatttagc aggactagct
     8941 gccgcatata cgacaaaaag tgatcaagta ggctttattg gtggaatgga agggcccgtg
     9001 atccaacgtt tccaaagcgg atttgaagct ggcgttaagg caggggccac agcactgaac
     9061 aaggaaatta ctgttaacgt acaatatgct gcatcctatg attcgctaga taaaggaaaa
     9121 gctattgctg cttctatgta caaagaggga gtcgatattc tttatcaggc ggcaggaagt
     9181 actggagctg gggtgttcca agaagcaaaa gcccgcaatg aaaacgacta tagcagaaaa
     9241 gtatgggtga ttggtgtaga tcgcgatcaa gcggatgaag gggattataa aatggagaac
     9301 ggcgagacag ggaatttcac gttgacttct acaaagaaaa atgtcggtgc agaagtcaaa
     9361 gaatttgcag aaacttctca taacgataaa tttcctggcg gcaagcattt gacctttggt
     9421 ttgaaagaag aaggggtaga tctgacaaaa ggacaattat cagaggaagc ctatcaggca
     9481 gtttcagacg caaaagagaa aatcatcagt ggtgatttca gactgtagac aaagtccatt
     9541 ttatggatga tgtctacagt attttctttt ataatagatt tatgaaaacg aatgcaagga
     9601 gtgatagcta tgatgtctaa aaacaatacg aatggtagaa atcaatttgc gatgcttacg
     9661 attgatgatc tagttcctca agatcatctc gttcgaaaga ttgatgccgc gcttgatttt
     9721 gaatttattt atccaatcgt cgaagccact tactccgatt taggtcgccc aagtatcgat
     9781 ccagtgattc tgatcaaatt ggtgtttatt cagtatttat tcggtatccg ttccatgcga
     9841 caaaccatta aggaagtcga taccaatgtc gcttaccgct ggtttttagg ctactccttc
     9901 gaggagaaaa tcccccattt ctcaactttt ggaaagaatt atgttcgccg atttagagaa
     9961 acgacggtgt ttgaggatat ttttgcctat attttagaac aagcagttaa agcaggtttt
    10021 gtaacagagg ataatttgta tctggattct acccacatca aagctaacgc caataaacat
    10081 aagtttacga aagaaatgac ccatgatgaa gcgaaagcct atcaggatga attagaagat
    10141 gagatcaatc gtcaacgaat agaggctgga aaacgccctt ttactttgga cttagaaaag
    10201 gaagtgaagc tgaaagaaag aaaaataagt aaagctgatc cggaaagcgg ctactacgtc
    10261 aaaggcgaac gagaaaaaca atttgcttat tctgcccata cttcatgcga cgacaatgga
    10321 tttattctta gcacaatcat cactcctgga aatatttatg acagtcaagt cgcctttcag
    10381 ctcgtcaaac aatcgaagag actttttcct gaaatcaatt gtgttgtcgc tgatgctggg
    10441 tataagacac ctaagtttgt tcactttttg actcatttga accttcgacc ttgtttgcct
    10501 tattcaaggc ccaaagggaa aaaggggcta ttatcaaaaa atgagtttct ctatgacgag
    10561 tattttgatt gttatatttg tccgcaagat caaatgctcg ctttttcaac ggttactcga
    10621 gaagggtacc gagaatacaa atccaatcca aaagaatgtg tgaactgtcc tctgctaaac
    10681 caatgtacca
//
LOCUS       DACBYO010000098        10318 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.098, whole genome shotgun sequence.
ACCESSION   DACBYO010000098 DACBYO010000000
VERSION     DACBYO010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.098"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(71..904)
                     /locus_tag="IVD26_002458"
     CDS             complement(71..904)
                     /locus_tag="IVD26_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAP6080382.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(1208..3373)
                     /locus_tag="IVD26_002459"
     CDS             complement(1208..3373)
                     /locus_tag="IVD26_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6080383.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            3633..5927
                     /locus_tag="IVD26_002460"
     CDS             3633..5927
                     /locus_tag="IVD26_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAP6080384.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5920..6585
                     /gene="pgmB"
                     /locus_tag="IVD26_002461"
     CDS             5920..6585
                     /gene="pgmB"
                     /locus_tag="IVD26_002461"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP6080385.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            6578..7585
                     /locus_tag="IVD26_002462"
     CDS             6578..7585
                     /locus_tag="IVD26_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP6080386.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            7607..8626
                     /locus_tag="IVD26_002463"
     CDS             7607..8626
                     /locus_tag="IVD26_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6080387.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(8907..10274)
                     /gene="nhaC"
                     /locus_tag="IVD26_002464"
     CDS             complement(8907..10274)
                     /gene="nhaC"
                     /locus_tag="IVD26_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAP6080388.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
BASE COUNT         3198 a         2242 c         1909 g         2969 t
ORIGIN      
        1 ctctccaaac ggtataatcg tttggagagt tttattttaa tcagtttttt tatgttatat
       61 gttatatttt ttattcgttc acatctaatt cgatttccac cccgtagtga tcactgatga
      121 ttggactatc gatcccatca aaaatccgtt gatatttttt aacctgcatt ccttcaggga
      181 cgaaaataaa atctatacgc aatttttctg tattttgttc ccaaccatct attttctttt
      241 ccacagtagc tgcttttcct ttttcattcg cgacaacata cgaatcttga agaagaaggc
      301 aactttctct tacagtataa taaccttgag agtctactgg attattgaaa tcacctagga
      361 aaaaaagtgg tacgcgagtt tccaaaaagt agttttccaa gtttttccac tcaaaataaa
      421 agccactttt tttatctgtc caccaagaaa agtggcagct cgagacaaaa atgtcctgat
      481 catctatctt tgttttccca atcaagatct tgcgtgtctg ataatcttct ttcttttgaa
      541 attgggagac ggtaaggacc tgactttcca atgttttttt cgtaagcagt gcatttcctt
      601 cttcatattt atcataaccg atgtggctca tttcccaact ccaaaaatac tcttttccgt
      661 gttcctttaa aagctgaact aaacggtagg caaaattatc tttacggata ggtacttgat
      721 tctttaccgg acagaacttc attagcttcg caggttctac ttcttcagat tccagtaatt
      781 ggttgatttc ttgtaaagca atcacttcat aatcttctaa caggatctta tctgctaatt
      841 cttgcaattt tttctctggt tctggctcaa gccagctatg cgtgttgagt gtcatgaatt
      901 tcattggttt tctccttgtc ttcatttcga aacaaaaggg ttgtgacaaa atttttgtca
      961 caacctctcc agcaaatagt gttctcctgc taactcctca gtaataagct caatggacca
     1021 ggagctattt tttgtttggc tgtttttatc acttggtgca gggcagcttt ttcacgacct
     1081 ctccactaaa cagtattcaa actgctgctt ctcggtaata agcccaacca aacgaaaaat
     1141 aggaggagct atttttgttt ggctgttctt atgacttgat gcaggacagc tttttcacaa
     1201 cctctcctta cattttaatg gagccgatca ctttaccagc tgtcactgta cctaattgct
     1261 tgatcactac ttcttctact ttatcgtttg taaatacgat catgatcgtt ggatcttttt
     1321 cttcgttttg gatcacatca agatccatct cagctaattt cgttcctgtt cctacttctt
     1381 ggccttcttt gacagcaatc tcaaaagctg gctgattcat ttggactgta tcgattccca
     1441 tatggatcaa aacttcgata ccatctttcg tttccagccc aattgcatgt ttgctaggga
     1501 aaatacttgt cacttttcca gcgatcggcg caacaacttc tcttgatgtt ggaataacag
     1561 caaagccgtc acccatcatt ttttgtgaga ataccggatc ttttacttca gataaaggaa
     1621 tcacttctcc agaagctgcg gaaactagtt cttgttctat acctaagtat tgcttactac
     1681 ctgcttgtcc atttcctgta gaaaccattt ctggctctgg aatctctgct cctgattgca
     1741 gcagatcttc gatatctgat ttcaagacat ctgcttttgg tccataaact gcttggactc
     1801 cattgtcttt gacgatcaat cccatcgccc ctgctcgttt ccaggcttct tcagtcccta
     1861 ctttttctcg atcatttaca cttacgcgta accgagtcat acaagcatcg acatctttga
     1921 tattttcttt tcctcccagc aaatgaatga tctggaccac ttgctgatct gctgttcctg
     1981 ttccgctgtt agatacaacg gtttcttcac tgtcattgtc gtaatttccg ttacgtcccg
     2041 gtgtagcaaa gttgaatttt ttgatcaaga aatttgctaa gaaatacgta acaacaccaa
     2101 aagcgatcac acacaacacg aagttgataa gatctccacc tagacccgct ttgatagcta
     2161 acggtgtccg agtcagcaat tcgatattcc caaatgaatg gacccgcaat ggcaagatat
     2221 ctgccatcgc aaatgcagcc ccttggatca ctgaataaat gacatataat ggcacagcag
     2281 caaacataaa catgaactcc aatggttctg ttacacctgt tagaaagaca gccaacgctg
     2341 ctgaaaaata cattgattta tatcttgctt tcttatcagg atcgacatta cgatacatcg
     2401 caaaagccat tcccatcaag atacctgaag aaccaatcat ttgtcctact ttgaaacgag
     2461 ccggcgtcca gttatgcaac acaaactcat attgcgacat atcccctgca cctttaagat
     2521 tcactaaatc agtggcccaa gccaaccata acggatcttg cccaaatact tgtgtccccg
     2581 cctgtgcgcc tgataaaatc tcatacgatc cgccaagctg tgtatagttg ataggaatcg
     2641 tcagcatatg atgcaatcca aatggcaata gtaaacgttc taatgttcca aataaaaacg
     2701 gtgctagaat cggtgcgctt tcttgtgatt ctgcaatcca taaaccaaaa ttattgattc
     2761 cagcctgtac gtttggccac accacagcaa gaatcaatgc cacgattgtt gaccataaga
     2821 taacaacaaa cggaacaaag cgctttccat tgaaaaatga caaagcatcc ggcaattttc
     2881 tataattata gtacttatta taagccattg ccccgacaaa tccagcgatg atccctacga
     2941 atactcccat attcaaagct ggtgcttcca atacacttgt aaaaaatcct ttaaccatga
     3001 tcttcgtacc gaacagagtg tgggtaaatg catcttcatt cgcaagcatg tcacttgtga
     3061 caccaaagat agccccagtg atccgattga ttaaaataaa tgagatccca gctgcaaatg
     3121 ctccgcctgc tctttctttt gcccaacttc ctcctattgc taaagcaaat aaaatatgaa
     3181 gattaccaat aattgcccaa ccaatatttt caattactcc gcccgttgtg acaagcggcg
     3241 tccaatcagg attgatcaag ggaattgatt tccctatact gatcatcaac ccagctgccg
     3301 gcataactgc taccacaacc attaaagcct ttccaaattt ttgccaaaac tcaaaactaa
     3361 atatcttttt cattccgttt agctccttta cgcaatcggt ttcgttaaac gtattatagc
     3421 gtgcgttttc ttttttgtaa atgctttatt ttttattttt ctgtctatac cattctataa
     3481 aacctataat acgtgtgttc ccttctataa ttttctccta aaaatttatt tttttaagct
     3541 tttttctatg aaatattttc ttttgtctat tgacttgtgc aatcggttgc gtttattatg
     3601 aacgtataaa acagctcatt aggaggagaa aaatgaaaca gatcaaacga ctatttgcta
     3661 ttgatccatg gaaaatcagc acgacacaat tagataaaaa aaatcttcga ctgcaagaat
     3721 ctttaacaag tattggaaac ggttatatgg ggatgcgcgg gaactttgaa gaaacttact
     3781 caggggacca ccatcaaggt acttatttgg cgggtgtctg gtatcccgat aagacacgtg
     3841 tcggctggtg gaaaaatggt tatccagaat actttggaaa agtgatcaac gccttgaact
     3901 ttatcgcgat agatatttcg atcaacgatc agctgatcga cttggcttct ttggaaccag
     3961 aagactttta ctgggaatta gatatgaaaa atggtgtatt atctcgtaca ttcacaatca
     4021 ctacttctac taataaagta cgcatttcct tcgaacgttt tctgagcatt gtcaaaaaag
     4081 aatcagctta tatctattta actatagaaa tgcttgaagg tagcggaaca gtcaaactcg
     4141 tatcaaaatt ggatggaaat gttcaaaacg aagacagcaa ctatgatgaa catttttgga
     4201 atgagattga tcgtggaact atagaagaaa tcggctattt gacgactaaa actattccaa
     4261 acaactttgg gattgaacaa tttactgtta ctgcagcaat gcgccatttc gttaatggaa
     4321 aatcagtcat ccctgactat cacgaagata ctttagcatt acatggttgc ttgtctgcag
     4381 aattatctca aggtgagaca tggtcagtgg aaaaagaaat tatcgttctt actagtagag
     4441 atattccaga agcgcagcaa gcagaaaaag ctgtctcaga attaacgaac cagacaaaca
     4501 attatatcca agcaaaagaa gagcaaacag cggcttgggc agaacgatgg aagcttgccg
     4561 atgtggtcat cgaaggagac gaagaagcac aacaaggtat tcgattcaat ttgttccaac
     4621 tattctctac ttactacggc gaagatgaac gattgaatat cggccccaaa ggattcacag
     4681 gagaaaaata cggcggagcc acttactggg atacagaagc gtatgctgtc cctctttatc
     4741 ttgctttagc caaacctgaa gtaactaaga atctgctgaa atatcggcat aatcaactgc
     4801 cgcaagcaat ccacaacgct cagcaacaag gattaaaagg cgcgctttat cctatggtca
     4861 ccttcactgg tgtcgaatgc cataacgagt gggaaatcac attcgaggag attcaccgaa
     4921 atggcgcgat tgcctatgca atctacaatt atacgaatta caccggcgat acggaatatt
     4981 tgaaaaatga aggactggaa gttttagcag aaatcgcacg cttctgggca gaccgtgtcc
     5041 atttttcaaa acgagcaaat aaatacatga tccacggtgt gaccggccca aacgaatatg
     5101 agaacaatat caataacaat tggtatacaa atacgatcgc agcttgggtc ttgcgttaca
     5161 cgcgagaaaa ttatttaact tatcaaaaag aagctgctat cactatcagc gaagaagaac
     5221 tagccaaatg gaaagatatc gcagagaaca tgtacttccc agttgacgaa gaattaggaa
     5281 tctttgtcca gcatgacaca ttcttagata aagatctcat gcctgtatcc gatattccca
     5341 caagcgatct tcctctgaat cagcattggt cttgggacaa aatccttaga tcttgcttca
     5401 tcaagcaggc agatgtacta caggggattt atttcttcaa tgatactttt acaaaagaag
     5461 aaaagcaaaa aaactttgat ttctatgaac caatgactgt ccatgagtct tccctttcgc
     5521 caagtatcca ttcgatttta gcagcagaat taggaatgga aagcaaagct gtagaaatgt
     5581 accagcgaac agctcgcttg gatttggata attacaataa cgacacagaa gacggcttgc
     5641 acatcacttc catgactggt agctggttgt cgattgtcca aggatttgct caaatgaaaa
     5701 ctgcccatga tcagttgaga ttcgcaccat ttctgccaaa aacttggaaa gcttattctt
     5761 tccatatcaa ttatcgcgga cgtttattgt tcatctcagt cacagatgaa caagttactt
     5821 tcgagttatt agaaggttct cctctagaaa tttacgtcta tgaacagtct tattctttag
     5881 cggatcgtct agaaataacg ctaagaaagg aggaagcaaa tgtttaaagg ggtattgttt
     5941 gatttagacg gtgtcattac cgatactgct gaattccatt atcgtgcttg gcgaaagctt
     6001 ggtcaggaaa tcggcattac gatcgaccac acattcaacg aacagctaaa aggcgtcagc
     6061 cgagaagact cactctcttt gcttttagct tatggcggaa aagaacactc tttttcaaag
     6121 gaagaatttg cagaattagc gaaaagaaaa aacgattatt atttagagat gatccagacg
     6181 atcgaaccaa aagatgtctt ccccggggtc gtgcctttac tggattcttt aaaagaagaa
     6241 aaaatcaaga ttgctcttgc ttctgcaagt aaaaacgggc cattcctact tgaaaaaatg
     6301 ggtcttacac cttactttga tgctattgcc gacccggcag aagcaacaaa cggaaaacct
     6361 gcgccagata tcttcctcct tgcagcaaaa gctgtcggac taaaagcaga agaatgtatc
     6421 gggatcgaag acgcgcaagc cggtatccaa gccatcctct caagtggcgc tcaaccaatt
     6481 ggcgtgggac gtgctgaaga ccttggagag gagatcccgc ttgtccctga tacgactttt
     6541 cttacgatcg attacttgaa agaaaagtgg catgaccatg gataatccag agatctccgt
     6601 cgtaccagtt ccagagactg aaataaagaa aatcacattg aagaacgact acttagaagt
     6661 cgttcttctc aattacggtg cccgcctgca ccaaatcttc gcaccagaca aagaaggaaa
     6721 atcagaaaat gttttattgt cttacgatcg tttcgaagat gttctaacag acaaaagctt
     6781 ttttggagca actgtcggac ctgtagccgg aaggatccgg gatgcttctt ggggtgagca
     6841 tagattggag aaaaactgcg gatcacacca tatccacggt ggcacgaaag gctggtcttt
     6901 ccaattttgg gaagtagaag ttttcaaaac tccatcatca ataggtgtgg tcttttactt
     6961 aaaagatgaa ttttctacct atccaggacc aatcactgct acgatcactt accgtttaac
     7021 aaaaaacgaa ttagagatga caacctctgc tagtagcctt gttgaaacca tctgcaatcc
     7081 gaccaaccat gcctacttca acctttcagg aaatggaaca agagacatct atgaacatca
     7141 gttaacggtc tttttagatg gtgtgcttga attagatcaa gaaaaactgc ctactggaaa
     7201 ttggacaaaa aaagaaaaac tgccaatcga ctttagaaaa tccccaacac tgcaagagat
     7261 ccttgcatgt tatccagatg gactagatga tgtatttctt ttgcatcatc ctaggctttc
     7321 caaaacttcc ttacaattat tcgagaagca ttctggtcgc caaatgacta tagcaacttc
     7381 taataaaagt atggtattat tttctacgac tggattcgaa gctgatttct ctgtcaatgg
     7441 aaaacagatg cattcaaact acggattagc aatcgaaccg caagaaatcc ctgatatcgt
     7501 tcatttcccc aaatttggat cgatcaacct ccatcctggt caagaacgga tcagtcagac
     7561 gatttatcgg ttctctgcac aataacaaga gaaaggtgtt tttatcatgg ctattaccgt
     7621 aaaagatgtg gcgaaaaaag ccggtgttgc cacctcgacc gtctctcgtg tcatcaacga
     7681 tcatcctagt atttccgaga caacaaagaa gaaagtccga aaaattatgg atgaactagg
     7741 ttatgttcct aacatgactg cccgcaatct aggaaaacgc atttccagtg ccatcggcgt
     7801 aatcttaccc cctcttgatt caaaagagcg gatcggtaac ccattttatc ttgagatcat
     7861 ggaagcaatc aacgaagaag cgcggaatta tgatatgact acagcaatcg ctactgctaa
     7921 aaattttgaa ttgctgttag agaacgtcca gcgtatgcat ttacaaaaac aagtagatgg
     7981 ttttattcta gtgtattcag atagtcaaga tactgtcatt gattatttat accaaaacca
     8041 catccctttc actttgatcg gacagcctta tcatcatgag aacgaaatcg tttatgtaga
     8101 taatgataac cagcttctag gtaaacaagc aacagaattt ttgatccaga atggacataa
     8161 gaatatcctg tttgtgacaa acacgactca tgaaagtttg tatttcgaac gatatttcgg
     8221 ttatcaaaaa gcaatgatga tggctggtct tcctgcgtta tccagtgtag tactagagca
     8281 tccggaggat tatctgtcct ttgagaaaac gttgaaagaa aacgaagcca cagcattggt
     8341 ggtcattgac gatatcttcg cccttcgcac gatgcagttg gcgcaaatgt atggctatgt
     8401 cattccagag acactctccg tcattagctt caacaactcg atcttctcaa cattaacaca
     8461 cccttacctt acaagtatcg atatcgatat ctccgaatta ggacgtgtcg ctatgcaaaa
     8521 gctgcgcgaa ttgatccatg aagaattgag cagtggcgta cgtttggtca tccctcatcg
     8581 cttgatcaaa agagagacag tcgttccttt agaaaaccca tactaaatag ctgactcact
     8641 aaatacgctg accatttatc ctatggtcag ctttttatgt aaaagaagat actacttcta
     8701 acacattgtt tatctgtaaa aaagagcgtg ggacaaaagt aaagaacact tttgtctcac
     8761 gctctaaaca cgtataaacg gcggaagcag aagcaactcc ttcggaaata agctgaaatt
     8821 cacaaaaatt taaaaagcaa ttttcttgag tttcttctta tttcttggag ttaaacgctt
     8881 ctgtcccagc ctcttttttc cttccttcaa ttttttacac gtcgacgatt caataaaaaa
     8941 ccgcctaata ttgtaaagac aggtgcaaga atcgagaaaa aggcgaatgg caagtaatgc
     9001 aacgcgctaa ctttcatcgt tcccataatg aatgtgccgc tgactcccca cggtacgaga
     9061 gaattgacgg tcgcacctga atccgctagt gttcgtgtca aataggtttt tgataagcca
     9121 acgtcatcaa aagaacgctt gaatgtttct cctggaagaa tgatggacag atactgttct
     9181 ccaacgatca gattgattcc gatacagctc aaggcagtaa acccgactaa acgagaaggt
     9241 cggtccatct tttcttttaa ttcttgaacg atggtatcaa cgatcagata tttgatcagt
     9301 aacccaccta atgccaatgc aagtaaaatc aaactagcag aacctaacat actcatgatc
     9361 ccgcctcgag aaagcagttc atctagcttt ggatcaggtg tatttgcgac ataaccattc
     9421 atcaagatgt ctgctgcttt tccgaccgtc aaacttttct catggataaa agaaagaacg
     9481 agagcagctg tcgatcccgc tagtaatgta gggatagccg gaattttttt gattgccccc
     9541 ccaaataaaa taactagtgg aatcaatgtc caaggagaga tccaaaagct cgctttcatg
     9601 ttttggatca tttcattgat actagctaga tcggctgaat gactgttatg tcctaatatc
     9661 gtataaaaaa tcaacgaaag gacgaatgct gggaaatccg tataacgcat accagcgata
     9721 tgttcgaata gattaactcc tccaataccc gctgccaagt tggtcgtatc tgataaaggc
     9781 gagcagttat tccctaaaaa ggcaccggaa acgactgcgc ctgtagtcat tgcatcattg
     9841 aatccaagta aatgaccgat ccccaaaaaa gcaattccaa tcgtcgaaat cgttgtaaat
     9901 gaactgccga cagtcactcc gacaattgca caaacaagaa atgctgtcgg taaaaagaaa
     9961 cgcacagaaa caagtttaaa tccataaacc ataatcgtag ggatggttcc agataaaatc
    10021 catgaagcaa ctaagacacc aatcaaaaga aaaatcagga ttggaatgat ccctggagtg
    10081 attcctttga tgatcccgtc atggatctca tcccatgtga actttttaaa tctgccataa
    10141 aacaacaaac acatgaaagc tgcaaggatc gggatatgtg gcgagagctg gaatccgatg
    10201 atcagtactc ctaggagtgc caacaacacg atcaatacag cgatactttc ttttaaagaa
    10261 atatttttat tcatcgtcga tctcctattt caaatgaaaa ggccctgcca tgaaaaaa
//
LOCUS       DACBYO010000099        10020 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.099, whole genome shotgun sequence.
ACCESSION   DACBYO010000099 DACBYO010000000
VERSION     DACBYO010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10020
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.099"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..722)
                     /locus_tag="IVD26_002465"
     CDS             complement(<1..722)
                     /locus_tag="IVD26_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP6080389.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     KPGMATVFLTNFIRCRTSFRML"
     gene            complement(727..1494)
                     /locus_tag="IVD26_002466"
     CDS             complement(727..1494)
                     /locus_tag="IVD26_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP6080390.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1982..2407
                     /gene="lacA"
                     /locus_tag="IVD26_002467"
     CDS             1982..2407
                     /gene="lacA"
                     /locus_tag="IVD26_002467"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HAP6080391.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2424..2939
                     /gene="lacB"
                     /locus_tag="IVD26_002468"
     CDS             2424..2939
                     /gene="lacB"
                     /locus_tag="IVD26_002468"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HAP6080392.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2950..3882
                     /gene="lacC"
                     /locus_tag="IVD26_002469"
     CDS             2950..3882
                     /gene="lacC"
                     /locus_tag="IVD26_002469"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HAP6080393.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTVSHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3885..4865
                     /gene="lacD"
                     /locus_tag="IVD26_002470"
     CDS             3885..4865
                     /gene="lacD"
                     /locus_tag="IVD26_002470"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAP6080394.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDLRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4893..5210
                     /locus_tag="IVD26_002471"
     CDS             4893..5210
                     /locus_tag="IVD26_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP6080395.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5210..6916
                     /locus_tag="IVD26_002472"
     CDS             5210..6916
                     /locus_tag="IVD26_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6080396.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTVLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            7058..8464
                     /gene="lacG"
                     /locus_tag="IVD26_002473"
     CDS             7058..8464
                     /gene="lacG"
                     /locus_tag="IVD26_002473"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAP6080397.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8487..8759
                     /locus_tag="IVD26_002474"
     CDS             8487..8759
                     /locus_tag="IVD26_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HAP6080398.1"
                     /translation="MLSDTLEKVQHLFRPGFEKVYIVSFEDCPMIPELEATPLLKCGK
                     WYVSTGKEWICHSDLELSAFEWEFLQSLDVEIRETIHFEVNYLPFQ"
     gene            8780..9679
                     /locus_tag="IVD26_002475"
     CDS             8780..9679
                     /locus_tag="IVD26_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAP6080399.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3163 a         1689 c         2007 g         3161 t
ORIGIN      
        1 aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac tgttgccatt
       61 ccaggtttat gacgactttt ggaagtaaaa atccatccat tatctttata atcaggattg
      121 aatcttatat gttggtgatt taactcaatt tcctctttaa gaatttctat agccctttta
      181 gataattgga cattttggta actttgtaag ttttttacat taccttcata gctattttct
      241 gcagctcctc cgtgagtgga ctgactaatg atgatatttt gcttttcaaa atattgatag
      301 gcaccaatat tttggagttt tcgactctgt aagtcaacag ggccattagt tagaatacct
      361 attgggatgc ggtttttatg tagagccagc agtagttgat gtatctcagg aatcatcgta
      421 atctgatcga gttcatattc atagtcagct tggaagtcta gagcttctgt cctagaaata
      481 ctatcgatgc caaattcttc catagtcttc tgacagcgaa aaattctaag ctgctcaata
      541 ctgatgagtt ttttcgtgta tttaggaaaa gcaacatcag accaacatct gaaacgtttg
      601 taaatgttat ctatttgttg gatatcaatc gttggaaaac atttctcaac gctacgttta
      661 aaggggagtt gatggtcata aagagtgtca tcaaggtcaa aaacaatatt tttataagtc
      721 ataattctag tccgctttta aaatagtagt gtactggcta aattcctcta agtgttgagg
      781 gctaatctgg ttatctgtaa tgatggtatc gagttgatct agattataga agttaaagaa
      841 atcgtatcga tcgaatttag tactgtctac taataagaat ttttctacag cattgtttag
      901 ggcaagttgt tgaatcacac cttccttgtc actatatgta gcaatagaat tatgggtaac
      961 agcatttgca ctaacaaaag ctttggcaaa tctaattgct tttaaatttg tcgaagccat
     1021 tgaacctaca aaagctccag ttatttctct atattcaccg ccaagaagca ataaatcaat
     1081 ggtttcgcta tcatttagaa tcaagaacac agggagacta tttgtaatga cacgaatttt
     1141 ataaccttta cgacctttca attctaatgc cagttgttca agtgtagttc cgggtccaat
     1201 aaaaatagta tcgccatctt tgattaaaga gcaggctttt ttagcaatgt caattttttc
     1261 ttttgtattt agacttttct tctcgatatg tgtcttttca agtggctttt tagaggaaag
     1321 taattgtgca ccaccatgag tacgtgttaa aagtccatca gcttctagag catcaaggtc
     1381 tctacgggct gtcatatcgg aaatatctag ttcatctatt atttctttta tggttatggt
     1441 cccatcaatc tttaacatat ctaaaatttt ttctaatcgt cgttttttgt tcatatgaag
     1501 acccttcttt cataaagtaa tttttttcca aagataattc tcttttaatt gtatcataaa
     1561 agacaatatt ttcaaggtaa aacaaacaat ttcaaacaaa aacaaatgtt agatgatgaa
     1621 ataagaacag tggattgacg tatattagct taggtcagat tttgtataag acgaaaataa
     1681 agtaggacct cttaatcagt aagttataga aagtaaaaga cttttgtaat acttgaatag
     1741 atatttcacg tccattttgt gatggattaa atgaacaaaa atgaacaata atttaacggt
     1801 gttatctatt ttttaaaaaa acaaataaaa aaacaaaaaa taaacaaaaa agtgttgctt
     1861 tttgtttgaa tgcttgatat tatataaaca aagaaatgat gaaaacgttt tttcgaacat
     1921 tttgcaaaat gttttctact tctacgtagc atttctttct aaaatttagg aggtggtcaa
     1981 aatggctatt gttgttggtg cagatctcaa aggtacgaga ttaaaagatg ttgtgaaaaa
     2041 ttttcttgta gaagaaggtt ttgaggtaat tgatgtgact aaggacggac aagattttgt
     2101 tgatgttacc ttggcagttg cctctgaagt aaataaagat gagcaaaact taggtattgt
     2161 aattgatgct tatggagctg gtccattcat ggtagcaact aaaattaaag gtatggttgc
     2221 agcagaagtt tcagatgaac gctcagctta tatgacacgt ggacataaca attcacgaat
     2281 gattacggtt ggcgctgaaa tcgtcggtga tgagcttgct aaaaacatcg ctaaaggttt
     2341 tgtcaatggt aaatatgatg gcggacgtca tcaaatccga gtagatatgc ttaacaaaat
     2401 gtgttaagga aaggagttaa ggaatgagaa tcgcaattgg atgtgaccac attgtcacag
     2461 atgaaaaaat ggcagtatca gaattcttga aatcaaaagg acatgaggtc cttgatttcg
     2521 ggacatatga ccacgcacgt actcactacc ctatctatgg taaaaaagtc ggtgaagcag
     2581 tagtaagtgg tcaagcagac ttgggagtat gtatctgtgg tacaggtgtc ggcattaaca
     2641 atgcagtcaa taaagttcca ggtgttcgct cagcgttggt tcgtgatatg acatcagcta
     2701 tatatgcaaa agaagagtta aatgcgaatg ttatcggttt cggtggaaag attactggtg
     2761 gtcttcttat gaatgacatc attgaagctt tcattgaagc tgagtacaaa ccaacagaag
     2821 aaaataaaaa attgattgca aaaatcgaac acgttgaaac acataatgca catcaagcag
     2881 atgaagattt ctttacagaa ttccttgaaa gatgggaccg tggtgactac cacgattaag
     2941 gtataacaaa tgattctgac agtcacacta aatccttcag tagacatctc ttatcctcta
     3001 gaaacattga aaattgatac agtgaatagg gtgaaagatg ttagtaagac agctggtgga
     3061 aaaggcttaa atgttactag agtcttgtat gaatctggtg ataaagttac tgctacaggt
     3121 ttcttaggtg gtaaaattgg tgaatttatt gaaagcgaat tagaacaatc tcctgttagt
     3181 ccagcttttt ataaaatctc aggaaacact agaaactgta ttgctatctt acacgagggt
     3241 aaccaaacag aaattttgga acaaggacca acagtttctc atgaagaagc agaaggtttt
     3301 cttgaccact atagcaatct tattaaacaa tcagaagttg tgacaatttc aggaagttta
     3361 ccttcaggac ttcccaacga ttattatgaa aaacttatcc aacttgcttc ggatgaagga
     3421 gtagcagtcg ttttggattg ttcaggtgca cctcttgaaa cagttctaaa atcgtcggct
     3481 aaacctactg ccatcaaacc taataatgag gaactttcac agttgcttgg aaaagaagta
     3541 acaaaagata ttgaagaact caaagacgtt cttaaagagt cactttttag tggtatcgaa
     3601 tggatagtgg tctcattagg tcgaaacggt gcctttgcaa aacatggtga tgttttctat
     3661 aaggtagata ttcctgatat cccagttgtt aatccagtcg gatcagggga ctcaacggta
     3721 gctggtattg catcagcttt aaatagtaaa aaaagtgacg ctgacttatt aaaacatgcg
     3781 atgacattgg gtatgttaaa tgctcaagaa acaatgacag ggcatgtgaa tatgactaat
     3841 tacgaaacac taaactcaca aattggagta aaagaggtat aaaaatggta cttacagaac
     3901 agaaacgcaa atctttggaa aaaatttcag ataaaaacgg tgttatctca gctttggcat
     3961 ttgaccaacg tggtgctttg aaacgtttga tggcacagta tcaagataca gaaccaactg
     4021 tagctcaaat ggaagaacta aaggttttgg ttgctgatga acttacaaaa tacgcttctt
     4081 caatgttgct tgaccctgaa tatggacttc cagcaacaaa agcattggat aaagaagcag
     4141 gtcttcttct tgcctatgaa aaaacaggtt atgatacatc aagtacaaaa cgtttgcctg
     4201 actgcttgga tgtttggtct gcaaaacgta tcaaagagca aggcgctgat gccgttaagt
     4261 tcttgcttta ctatgatgta gacagctcag atgaacttaa ccaacaaaaa caagcttata
     4321 ttgaacgtgt tggttctgaa tgtgtcgctg aagatattcc tttcttcttg gaaatccttg
     4381 cttatgatga agaaatctca gatgcaggtt ctgttgaata tgcaaaagtg aaacctcgca
     4441 aagtcattga agcgatgaaa gttttctctg atctacgctt taacattgat gttcttaaag
     4501 tagaagtacc agttaacgtt aaatatgtcg aaggttttgc tgatggtgaa gtggtttaca
     4561 gtaaagctga agctgctgac ttctttaaag cacaagaaga agcgactaac cttccataca
     4621 tctacctaag tgcaggtgta tctgctaaat tgttccaaga aacattgcaa tttgctcacg
     4681 actcaggtgc caagtttaat ggtgtgcttt gtggacgtgc tacttgggca ggatctgtag
     4741 aaccttacat caaagaaggt gaaaaagcag cacgtgaatg gttgcgtact actggattcg
     4801 aaaatattga tgaacttaac aaagttcttg ttaaaacagc tagtccatgg actgataaag
     4861 tatagtaaaa acataaaacg gaggatattg ttatgaacag agaagagatg actctcttag
     4921 ggtttgaaat tgttgcttat gctggagatg ctcgctctaa acttttagaa gcgcttaaag
     4981 cggctgaaaa tggtgatttc gctaaggcag atagtcttgt agtagaagca ggaagctgta
     5041 ttgcagaggc tcacaattct cagacagcta tgttggctcg agaagcttct ggggaggaac
     5101 ttccatacag cgttaccatg atgcatggtc aggaccactt aatgactact gtcttattaa
     5161 aagatgtgat tcatcacctc atcgaacttt ataaaagagg agcaaaataa tgcataaact
     5221 cattgaactt attgagaaag ggaaaccgtt ctttgagaaa atctctcgaa acatctatct
     5281 tcgtgctatt cgtgatggat ttatcgctgg tatgccagtc atccttttct catctatctt
     5341 tatccttatt gcctatgtcc caaatgcttg gggattccac tggtcaaaag acattgagac
     5401 cttcttgatg actccttata gctattcgat gggtatccta gcattctttg ttggtggtac
     5461 taccgctaaa gctttgacgg actcaatgaa ccgtgaccta cctgcgacca atcagattaa
     5521 cttcttatct acgatgctag cgtctatggt agggttcctt ttgatggcag ctgagcctgc
     5581 aaaagaagga ggcttcttga cagccttcac gggaacaaaa ggtcttttga cagcatttat
     5641 tgcagccttt gtgacagtta atgtttacaa ggtctgtgtg aaaaataatg ttactattcg
     5701 tatgcctgaa gaggttccac caaatatctc tcaagtattt aaagacttga ttccattcac
     5761 tgtagcggtt gttctccttt atggatttga actcattgtt aagggaactc ttggtgtaac
     5821 cgttgcagaa tcaatcggta ccgttcttgc tcctctcttc tcagctgcag atggttacct
     5881 tggaattaca cttatctttg gtgcttatgc cttcttctgg tttgttggta tccacggtcc
     5941 ttcaattgtc gaaccagcaa tcgctgctat cacttatgcc aatatcgatg ccaacttgca
     6001 tcttatccaa gctggacaac atgcagataa agttatcact tctggtactc aaatgtttat
     6061 tgttaccatg ggtggaacag gagctacatt gattgttcca ttcttgttca tgtggatttg
     6121 taaatcagaa cgtaaccgtg ccatcggacg tgcctcagtt gttccaacat tctttggggt
     6181 taatgagcca atcttatttg gtgcaccaat cgtattgaat ccgattttct ttgtaccgtt
     6241 cattttcgct ccgattgtca acgtttggat ctttaaattc tttgttgaca cattgaacat
     6301 gaactcattc tctgccaacc ttccatgggt tactcctggt ccgttgggaa ttgtactcgg
     6361 tactaacttc caagttctat catttatctt agccggactc ttggtagttg ttgatactat
     6421 catttattac ccatttgtta aggtatacga tgaacaaatt cttgaagaag aacgttctgg
     6481 taaaacaaac gatgctctta aagaaaaagt agctgcaaac ttcaatactg ctaaagcaga
     6541 tgccgttctt ggaaaagcag gcgttgctaa agaagatgta gcagcaaaca ataatatcac
     6601 aaaagaaact aatgtccttg ttctttgtgc aggtggaggt acaagtggct tgcttgccaa
     6661 tgccttgaac aaagcagcag cagaatacaa tgttccagtc aaagcggcag cgggtagtta
     6721 cggtgctcac cgtgaaatgt tgccagagtt tgacttggtt atcttggctc cacaggtcgc
     6781 ttcaaacttc gatgatatga aggctgaaac ggataaattg ggcattaaac ttgcaaaaac
     6841 tgaaggagct caatatatca aattgacacg tgatggacaa ggtgctcttg catttgttca
     6901 acaacagttt gattaataaa tttgtaaaag ttatttgaga cgagattatt ctttcagttc
     6961 cttataatat tgttaaccat atcattgcat ttcatttcct tggtttccgg aactcagaat
     7021 atcgtctcaa atgctttttt tgaaaggatt tatagttatg actaaaacac ttcctaaaga
     7081 ttttattttt ggtggtgcta cagctgctta tcaagcagaa ggtgcgactc acacggatgg
     7141 taaaggccca gttgcatggg ataagtatct tgaagacaat tattggtaca cagcagagcc
     7201 tgcaagtgat ttttaccata aatatcctgt tgatttagaa ttagctgaaa aatatggcgt
     7261 taatggtatt cgtatttcaa ttgcctggtc tcgtattttc ccaactggct atggcgaagt
     7321 aaatgaaaaa ggtgttgaat tctaccataa tctttttgcc gagtgccaca aacgtcatgt
     7381 tgagccattc gtgactttgc accactttga cacaccagaa gttcttcact cagatggaga
     7441 tttcttaaac cgcgaaaata tagaacactt tgtagattat gccgctttct gttttgaaga
     7501 gttcccagaa gtaaactact ggacaacttt caatgaaatt ggcccaattg gagatggtca
     7561 atacttggtt ggtaaattcc ctccaggcat tcaatatgat cttgccaaag tcttccaatc
     7621 acaccacaat atgatggttt ctcatgcacg tgctgtgaaa ttgtataaag ataaaggtta
     7681 taaaggcgaa attggtgtag tacatgcgtt gccaaccaaa tacccttatg atccagaaaa
     7741 tccagcagat gttcgtgccg ctgagttaga agatatcatc cataacaaat ttatcttgga
     7801 tgcaacctac cttggacact attcagataa aacgatggaa ggggtcaacc acatcctagc
     7861 tgaaaatggt ggagaacttg atcttcgtga tgaagacttc caagcacttg aagcagctaa
     7921 agatttgaac gatttccttg gtatcaacta ctacatgagt gattggatgc aagcctttga
     7981 tggtgagact gaaatcattc acaatggtaa gggtgaaaaa ggaagttcta agtaccagat
     8041 taaaggtgtt ggtcgccgaa tcgcaccaga ttatgtgcct agaacggatt gggactggat
     8101 tatttatcct gaaggcttgt atgaccaaat catgcgagtg aaaaatgatt atccaaacta
     8161 caagaagatt tacatcactg aaaacggtct tggatacaaa gatgagtttg tagataatac
     8221 cgtttatgat gatggtcgta ttgattacgt gaagaaacac ttggaagttt tatcagacgc
     8281 aattgcggat ggtgcaaatg ttaaaggtta cttcatctgg tcacttatgg atgtcttctc
     8341 atggtcaaac ggatacgaaa aacgttatgg actattctat gtagactttg acacgcaaga
     8401 acgctatcct aagaaatcag ctcattggta taagaaagta gcagaaactc aagtgataga
     8461 gtaatattac ttgaaaatgt aaaaaattgt tatccgatac tttagaaaaa gtacaacact
     8521 tatttagacc aggctttgaa aaggtatata ttgttagttt cgaagattgt cctatgattc
     8581 ctgagcttga agctaccccg ttgctaaaat gtggtaaatg gtatgtttca actggaaaag
     8641 agtggatttg ccattctgat ttagagttat cagcatttga atgggaattt ttacaatcac
     8701 tcgatgtaga aatacgtgag actattcact tcgaggtaaa ttatttgcct ttccaataat
     8761 aaaaagaaag gaattagttg tgactatcga attaaaaaac gagtatctta ctgttcagtt
     8821 taaaacactt ggtggtcaac tgacttcgat taaagacaag gatgggatag agtatctctg
     8881 gcaagctgat ccaaattatt ggaatggaca ggcgcctatt ctatttccta tctgtggtag
     8941 tttacgaaat gattgggcta tttatagacc tcaagaaaga ccttttttta caggtcttat
     9001 tcgtagacat ggttttgttc gaaaagaaga atttattctg gaagaagtca atgataatag
     9061 cgtgaccttt agtattaaac caaatgctga gatgcttgat aattacctat atcagtttga
     9121 actgagagtt gtttatacct tgaatggtaa atcaattaga accgaatttc aggtaacgaa
     9181 cttggaaatg gaaaaaacaa tgccttactt tattggagcc catccagcat tcaatagtcc
     9241 tttagtagaa ggtgaaaact atgaggatta ttatattgaa tttagtgagg ttgagtcttg
     9301 ctcgatacca aagagttttc ctgagacagg attattagat ttgcaagatc ggacaccttt
     9361 tttggaaaat caaaaaattc tcgatttgga ctactcactt ttttcccatg atgccattac
     9421 acttgaccag ctcaagtctc gtagcgtaac gcttcggtca aggaagtctg gtaaaggtct
     9481 tcgagtagat tttgatgatt ttccgaactt gattctgtgg tctacaacta ataaaagtcc
     9541 attcattgct ttggaacctt ggagtggtct ctccacttca cttgaagaag gtaatttctt
     9601 agaagataaa agacaggtaa cgaaaatttc acctcaagaa acttctagaa aaatctatga
     9661 tattactatc cttaattaaa atttgttatt atttgagtct tcaataagat ttgaatactc
     9721 ttaccttgtg atgatagatt ggtcttctcc gtgccagtct tacatcgcaa ggtttttaag
     9781 ttttttgtgg gtctatgtca actgtagtgg gtgacgaaaa gctaatatct aaagacagtc
     9841 tggtagtaaa aaataagatt atttactact tcttgattta aaataatagt ggagccatta
     9901 atttgtggca aatttaattt aatattttgc ctcaaattag ccacactttt tatagaacta
     9961 agaggaaaaa tgaaattttc ttcctattaa tatagttgtt tgaaatctta aatatagcgt
//
LOCUS       DACBYO010000100         9890 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.100, whole genome shotgun sequence.
ACCESSION   DACBYO010000100 DACBYO010000000
VERSION     DACBYO010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.100"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            403..1452
                     /locus_tag="IVD26_002476"
     CDS             403..1452
                     /locus_tag="IVD26_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6080400.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            1449..2330
                     /locus_tag="IVD26_002477"
     CDS             1449..2330
                     /locus_tag="IVD26_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6080401.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            2333..3103
                     /locus_tag="IVD26_002478"
     CDS             2333..3103
                     /locus_tag="IVD26_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP6080402.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            3382..4236
                     /gene="aroE"
                     /locus_tag="IVD26_002479"
     CDS             3382..4236
                     /gene="aroE"
                     /locus_tag="IVD26_002479"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAP6080403.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            4414..5577
                     /locus_tag="IVD26_002480"
     CDS             4414..5577
                     /locus_tag="IVD26_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAP6080404.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            5694..6104
                     /locus_tag="IVD26_002481"
     CDS             5694..6104
                     /locus_tag="IVD26_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP6080405.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6278..8506
                     /gene="topB"
                     /locus_tag="IVD26_002482"
     CDS             6278..8506
                     /gene="topB"
                     /locus_tag="IVD26_002482"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP6080406.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            8644..8961
                     /locus_tag="IVD26_002483"
     CDS             8644..8961
                     /locus_tag="IVD26_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080407.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            9121..9357
                     /locus_tag="IVD26_002484"
     CDS             9121..9357
                     /locus_tag="IVD26_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP6080408.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            9354..9752
                     /locus_tag="IVD26_002485"
     CDS             9354..9752
                     /locus_tag="IVD26_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP6080409.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3453 a         1662 c         2085 g         2690 t
ORIGIN      
        1 tatcagaaca agtgatgttt gatcttcaaa ataacaaata aaaaattaaa aaatatagtt
       61 gacgaaattc aaaaattcga ttagacttaa atcaattctt aaggaaaggg tgacctgtaa
      121 tgaacttatc aaaacgtatt tcagcagaaa acaaaaaaaa ttggcgcagc tggcgtagat
      181 aagttgtatt aatggtgaga ctttcccata gatacaactt tttagagtgc atttctaaag
      241 cttgtatcta tgctagacat gaacattgac tgccgcatag attagaatct atgcggtttt
      301 ttgtgtaaag acaatgaccg ctttggccat tgtctttttt tgtagactgg atacttgcct
      361 gattataata aataaaaaga ttgactttgc aggaggaaaa aaatgaaaaa caaacgatta
      421 ataacagttg tagtaattat tttagtttat ttagcaggtg catttattta tggaaaagcc
      481 tcaggcgaaa aagaaagtac ttcgacgaac cagacaaaaa aaacaacagt tgttggggta
      541 ttgcaatacg tgagccatcc ggcattagat gagatttatc gaggaatcaa agatggtctg
      601 aaagaagaag gattaaaaga aggagaaaat cttgagatca aatttcaaaa tggacaagcc
      661 gatcagagca agctagccac aatgagtcaa cagctagtac aatctgatcc agatgccttg
      721 attggaatcg caacacctgc cgctcaatca ttagcaaaca cgacttcatc gatcccagtt
      781 gtgttaggtg ctgtaacgga tcctgtgggg gctggattag tcgcttcttt agagaaacct
      841 ggtggtaatg taacaggtgt ttctgatcag ccgcctgtta cttcacaaat caagcttgct
      901 tctgatttgt tgccaaatgc aaaaaaagtc ggaatcttgt atgcttcttc agaggataat
      961 tcaaaatacc aagtagcaca agcagaagaa gctgcaaaaa aagaagggtt agaatcagta
     1021 aaatatgcgg tgccttccac taatgagatt gcacaaacgg ttcaagtgat gagccgacaa
     1081 gtcgatttta tctatgttcc attagataat accattgcca atgcgatgca aacagtggta
     1141 aaagaagcaa acaaagcaaa tatccccgtc attccatctg tggatacaat ggtggaacaa
     1201 ggtggactag caacaatcgg gatcaatcaa tatcaattag ggcttcaaag cggtaagatg
     1261 gcggcagaac ttgcgagtgg aaaagaaaaa ccggaaacga cgcctgttta tacatttgat
     1321 caaggggata cagtgatcaa tcaatctcaa gctgatcgct taggaatcat tgttccccaa
     1381 tcgatgaagg aaaaagccaa aatcattaca gatgactcgc agcaagaaac atctaaggag
     1441 gatgacaaat gatcgtatca gctatttcac aaggcatgct ttgggcaata ttaggattag
     1501 ggattttcat gacttatcgg atcttagact ttcctgatat gacgacagaa gggtccttcc
     1561 cattaggtgc tgctgtctgt gtgacagcta ttactcatgg ggtagcgccg attgtagcta
     1621 cattattagg cgtaggtgct ggcatgatag caggactcgt tacggggtta ctttatacaa
     1681 aaggaaagat accggttatt ttagcaggga ttttagtgat gtcaggattg aactcagtta
     1741 ttttgtttgt gatgcgaaca ccaaatcttt ctttattgaa tcatccgatt ctacaagaca
     1801 gcttccatcg ctttgggtta cctgattact ttgacacagt ccttcttggc ttcatctctt
     1861 tgggcatctt gattgctgta ctgctattct tcttcaatac agatttgggt caaggctata
     1921 ttgcgacagg agacaacgaa acgatggctc ggtcgttagg gataaaaacc gatcgtatga
     1981 aaattttagg tttaactttg tcgaacggtg tcattgcatt atccggtgcg ctgattgccc
     2041 agaacgacgg atatgcagat gtaaataaag ggattggcgt aatcgtcatc ggtcttgctt
     2101 ccatcatcat cggtgaagtg atcttccaag aattgacgct agcagaaaga ttgattgcta
     2161 ttgttgtcgg cagtatcatt tatcagctat tgattttagt agtaatcaaa ctagggtttg
     2221 acacgactta tctgaagttg ttctccgcta tcatcttagc tatttgtctg atgatcccgc
     2281 aattgaagaa agcactgaac ttaaaaacgg gttttgagaa ggaggcatag taatgactga
     2341 tatattgaca atcaaaaatg gcagaaaagt cgtaaacaat ggaatgaatg aagagaaagt
     2401 actattggat gaaattaacc ttacaatcag agaaggggac ttcatcactg tccttggcgg
     2461 gaatggtgct ggaaaaagca cactgttcaa tacgatcgct ggtacgcttc aactcagtca
     2521 aggatcgatc tcttttaaag atcagctgat cacaaaagat tcagaagaaa aaagagcacg
     2581 attcctttct cgagttttcc aagaccccaa gatgggaacg gctcctcgga tgacagtagc
     2641 agaaaatttg ctacttgcac aaaaaagagg tcaaaaacgg aaattccgtt tacgtaactt
     2701 gaaaaatcaa aaagaagatt ttttcagact atgtcaagaa gtcggtaatg gcctagagca
     2761 acacttggat actccagcgg gtgaattatc tggtggtcaa cgccaagcat taagcttgct
     2821 gatggcgacg atcacagctc ctgagttact attattagat gaacatactg cagctttaga
     2881 tcctaaaaca gctaaagcat taatgcgatt aacaaatcag cggatcaatg aacaaaaatt
     2941 gacttgtctc atgatcacgc atcgaatgga agacgccttg aaatacggaa atcgtctgat
     3001 cgtactccaa aaagggaaaa tcgttcaaga tatttctgaa aaagaaaagc aacatttgac
     3061 aatgggcgac cttttgcagt tctttgaaga agtagtggat tgatttcgac agaaaaattc
     3121 ctttcagtag aaggacttga aaactcattg acatcttcct ttgattcatc ctatacttaa
     3181 aacaataaac aattaaacat atttgggtgt tttgtaggat cacgtagtca atgattttaa
     3241 caattaaata gaatattctt tgctctgaca agtaaacgat gagaaaagaa tttgctactt
     3301 tgccacctag acgtttcgta ctttttcgta tcaaacgcta agtggctttt tttattgaag
     3361 taagaacaaa ggaggaataa gatgatttct ggacaaacca aattagctgg gctctttgct
     3421 gatccggctt ctcacagttt atccccattg atgcacaata ctgcttttga agcaaacaac
     3481 atcgatgcgg tgtatttagc tttccaagta aatccaatga atttgaagca agcagtcgaa
     3541 agtattcgaa cttttgatat gttaggtgta aatctttcga tgccgaataa aacagcggtt
     3601 attccttatc tggatgaggt aagccaggaa gcgcaattga tcggagcagt gaatacgatc
     3661 gtgcacgaaa agggtcgttt gattggctat aataccgatg gtgcgggctt catgcaatcc
     3721 gtgcaagaag ctgggatttc gatcaaaaag aaaaaaatga ctctactggg agctggaggt
     3781 gcagcaaagg cagtcactgt tcaagctgcg ttagacggcg ctgaggaaat cgtagtttat
     3841 aaacgaaaca accaaacatt cgctcaagta aaagaaacat tcgaacaact cagctatcga
     3901 acttcttgta agataaaagt tcgtgacttt gccgatacgc atcaattaag aaaagacttg
     3961 aaagaaagct gtcttctagt caatgcaaca gatatcggga tgggaaagaa aatcaatcag
     4021 tcaccgctct tagatataag catgatgcat gagaatctag cggtttttga tttgatttat
     4081 gcacctagag aaacacgttt attaaaagaa gcaaaaaaag taggagcaaa aggatacaat
     4141 ggacttggca tgttgatcta ccaaggagca atcgcgtttg aattatggac aaaggaaaag
     4201 atgccgatcc atgtgattga aaagctgttt gattaaaaaa ggataataga taaagatctt
     4261 ttattctcgc ataaacggtc tcaagaaaag taatccttta tgtatcgaag catttatttc
     4321 gttatttttt attaaattat caaaaaatga taggcttttg tcgattggtt atcgtatcct
     4381 ttatttatca gtaagaaacg aggaggaacc acaatgagtc ggatggatcg ctataaggac
     4441 atccataaga aggcgaaacc tctgaagcgg gatacgggga gtatttttgc tagaagagaa
     4501 cgaaaacgaa cgcgtatgga aaatgaggaa gatgctaccc gtatttatga aagagagcag
     4561 cattcatttg aacatttgaa ccaatacgag caacagatat acagagatgc accaagagca
     4621 gaagaacaac aaaaaaataa aaaatttttc aatcggcaaa agaagaacaa accgttaaaa
     4681 cctcgaagaa agcgatcgtg gaaaaaaatc attctatcga ttttgcttgt tttgatcctt
     4741 tattcaggta tctcattttt tattggtaaa tatgtagctg aacatgacac aagcttagag
     4801 gcagcgactt cagaaacctt tcatgggcaa aaagcgacga atggtgcgca taatattttg
     4861 atccttggaa gtgatacacg cggagaagat gccgggcgag ccgatacgat catggtctta
     4921 cagttggatg gtccttccca taagccgaaa ctgatttctt ttatgcgtga cagcttcgtt
     4981 acgatcccag gggtaggaca aaataagatc aattcagctt atgcatacgg aggagccgat
     5041 ctagtgcgtc aaactttagt agaaaatttt ggaatcgatt gtcaatacta tgcgaaagtc
     5101 gatttcaaat cgtttgaaaa agtgatcgat gccttattca tgaacggagt gaagatcgat
     5161 gcagaaaaag atctgaatct ggatggtgta gatattaaaa aaggggtcca gaagatggat
     5221 ggacatgttc ttttgcagta cgcacgtttc cgaatggatg aacaaggaga ctttggccgt
     5281 gtcagacgcc aacagcaagt aatgaacgct attttcagcc aattgaagaa tccattgaat
     5341 ctgatccgtg caccttatgc agctggtaaa gctttaggat atacatccac agatgtcact
     5401 gcttggttct tgacgaaaaa cctcttttcg attgcacgag gagctggtgg cattgatcga
     5461 ataagtgtgc cagtagacgg ttcgtggaat tatgggcaaa gtgattatgc tggcagtatt
     5521 cttgaaattg ataatcaaat gaatcaatct gctattacag attttttgaa taaatgatca
     5581 taaaaaagat caagaagaag ctgcgcaagg cttttgtcat gaatcaatca aacgattcac
     5641 tcgtaaaaaa cgctttctta tggtagattt aaccaagaga ggagctgttt acattggata
     5701 tctatctgaa cttcaaaaat gagtcgcgtg aagccatcgc tttttatgaa aaagtttttc
     5761 agactgaagc atcaggtatc accacatacg gtgaaatgcc tggaatagaa caaatgaact
     5821 tgccagaaga agcaaaaaat ctaatcacga atgcacggct gaacatttat gatacattag
     5881 ttatgtttgc agatacgcca gaaggaattg gtcctgaatt agttgtggga aataatgttt
     5941 ctttagtcat ccagacaaga aatgaagaag aaacgaagcg cctatttgaa agcttagctg
     6001 agggtggtaa gattgagatg ccactggatg ctgttccgtg ggctcagttg tatgggatgg
     6061 taactgatcg atttggcatc aactggcaga ttaaccaaga gtgacagcta aagatgaata
     6121 ttttctggaa acatcaagca gcaaacggat catcgtttgt ttgcttgatg tttttgtgtc
     6181 tatttcgact atacggtatc ttttttttat tgccagatgc gaaaatatgt tccataatag
     6241 agaagtccgc aaaaaattaa gtaacggagg tcagaagatg aagacggtga tactagctga
     6301 aaaaccttca caagcaaaag cctatgccga aaccttccaa cagcaaaagc ggcatgaagg
     6361 gtattatgaa atcagcgatc cattgtttgc tggtgaagta accatcactt atggttttgg
     6421 acatttggta gatatggttg ctccaggagc ttatgaagag cgttgggcaa aatggtcttt
     6481 agaaaatttg cctattttcc cagaaacctt ccgttacgaa gttccaatgg acaaacgtgc
     6541 acaattttcg atcgtaaaac gagaattgca gtcagccgat accatcatta ttgcaacaga
     6601 tggtgatcga gaaggtgaag ccatcgcgtg gtcgattatt cgacaagcaa acgcattttc
     6661 taaggaaaag aactatttac gtttatggat caattctctt gaaaaagaag caatctatga
     6721 aggttttaag aatctccaac ctggaaagaa ctattttcca aaatataaag aagcgcaagc
     6781 aaggcagaac gctgattggc tgattggaat gaatggaagt ccattatata gcttgctact
     6841 tcaacgaaaa gggattgatg gcagtttttc tcttggtcgt gtacaaacac cgacactcta
     6901 tatgatttat cagctgcaag aagaaatcaa acacttcaaa aaagaaacgt actttgaagg
     6961 agaaggttta attacgacaa acaaagggca gttttctgga aaaatcgtac caaaaaaagc
     7021 atttaaaacc caagaagagt taacgaagga aatagaaaaa cttggagcgc atttaggtaa
     7081 gcaaaacgga cggattcttg aagttacgaa aaaggaaaag aggttgcata gtccacgttt
     7141 attttcgcta tctagtttgc agacaaagat gaatcagcta atgaaagcaa gtgccaaagc
     7201 tacacttgat gctgctcaag gattgtacga aagcaagttt ctaagctatc caagaacgga
     7261 ttccttttac attacagaaa atgagcatca gtatctggtt aaacatctgc aaaattataa
     7321 aaaattttta ggaatagaag aagtacagac aactgagatc aaagcaaaga aacgatatgt
     7381 cgatgcgaaa aaagttcaag aacatcatgc aattattccg acaaagacga ttccgactcc
     7441 tgcacgcttt gcgaagcttt ccaaattaca gcaagcaatc tatttgcaag ttttgcgcac
     7501 tactgtggct atgtttgctg cagattatat ctacgaagag acgaccgtaa tgacgggcgt
     7561 acagcaatta aagctaaaaa gcatcggaaa gatcccatta cagcaaggtt ggcaggaaat
     7621 cttacgcatc aagtcaaaaa agaaagaagc tcagactctt cctcctatcg tagaaaatga
     7681 agaagcagaa gtagaactga aaagtatgga gaaagaaaca caacctccaa aaccctatac
     7741 cgaaggaacg ttgatcacag caatgaaaac tgcgggaaaa acgctggata atgatgaagc
     7801 gcaagaaatt ctcaaagaag tagaaggaat agggacagaa gctacacgag ccaatatcat
     7861 tgaaaatctt aagcagaagc attacatcga agtcaataaa aacgaaataa ctgttacgcc
     7921 aaaaggaatc actctttgta aggcagtagc caatgaacca ttactgacga gcgcagaaat
     7981 gactgcgcgc tgggaagggt acttgagaaa aattggtaaa caagagggga caccatctgt
     8041 ttttttagag aatatcaaaa aattcatcct acatttattg gcagaagttc ctaatcaaat
     8101 cgacaaggta gacttttcag atgagattag cgggacacgt cagataaaag cgatggagaa
     8161 gaaaaacgat caattaggaa gatgtccaaa atgtaaaaag ggaatagtca tgctttatcc
     8221 taaaatcgct acatgcttga atccggaatg cgacttcaaa ttgtggccaa cagtagctaa
     8281 aaagaagctg actaaaacga atctcagaga tttgctttca aaaggaaaga caagtaaagt
     8341 tgtcaaaggt tttactggta aaaaagggaa attcgatgca gttttagtat taaaagaaga
     8401 tatgacaatc ggtttttctt ttccatggat cgaaaacagt ggaacaaaag cagttgatgg
     8461 aaacaaagaa acatcaagaa aaaataatga aaacgaagta gagtaaatga aaacaatgaa
     8521 atagcggaat atttattccg aaaagtgaga atataaatac caataaaact aaaaaatatc
     8581 agtgaatcaa gcaaaaacgt tggggtaggc tgattttata tagatagcaa ggagtttttt
     8641 tatttgaaaa aagtgcattc atttttaaat tatcttatgg gagcaatcac gattgtggct
     8701 gtgtaccaag catttctaaa gtatcctgat tacgggacga agttgttgtc attgacgcac
     8761 aatcaaacag catattcacc aacgttgatt ttatcgactt tgactgcagg agctaaaagc
     8821 gctacttatt tttttcataa aacgacaagc atgctaaagc gaaagaaaca gcgaaaacaa
     8881 ttgttggtgg tggtagcggc tatgatcatt atttattttc taccagttat tacacaagta
     8941 tttcatcaat attttggtta agaatacgag agtttgtgac aaaagtcatg tcacaaactt
     9001 ttttctttgt cattttttcg taagaaaaag caaaataaaa gtatatacat tgattaaaag
     9061 tatatacttg gatataatgt acttactata gaatgagaat ggtatagagg gtggcgaaat
     9121 atgaaaaaaa tgaaaaagta taaaattaga aaatctggca atagcgatgt aacaactatc
     9181 ccaccagaag taaaagaatt catgggtgtg cagacaggtg acgcaatcag ttatgttttt
     9241 caatctgatg gttctgtacg aatgatcaaa gcacaagaag aacctgatat tgattcatta
     9301 gttgattcga tcatgaatca atatgaagac gcgttaaaag atttggttga tttatgaggt
     9361 atctttcgac taaagaaatt atcaaaatca acgcgaaagt tattttacgt cactcgccag
     9421 gcgaaatgat cggtgtaaaa gatgcaaatg cattagatat ggccgtcaaa cagccttcac
     9481 aagcagtatt caatcaagaa ctctatcctg aaatctatga aaaagcggcg attttagcaa
     9541 ttaatttagc taaaaaacat ccttttcata atggcaataa acgaactgct cttgttgcca
     9601 tgttgttgtt tcttcaattg aataattgtc cagttgcttt ttctcgtcaa gaagctgttg
     9661 attttatcat aatgattacc actagttcat tggatttcga ttcactaaag tccaagataa
     9721 ccagttattt acgacaaacc gcaataaaat gaacgaatta aaaactttat ttctcaatta
     9781 gatcagcatg tcattaagga atatgctgat ttttttatgt ttaatcatac aaaatagttt
     9841 tttcataaaa atatggaaaa tatggattaa ttttgaaata attgatttaa
//
LOCUS       DACBYO010000101         9865 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.101, whole genome shotgun sequence.
ACCESSION   DACBYO010000101 DACBYO010000000
VERSION     DACBYO010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.101"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(22..267)
                     /locus_tag="IVD26_002486"
     CDS             complement(22..267)
                     /locus_tag="IVD26_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080410.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(382..960)
                     /locus_tag="IVD26_002487"
     CDS             complement(382..960)
                     /locus_tag="IVD26_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP6080411.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1037..1567)
                     /locus_tag="IVD26_002488"
     CDS             complement(1037..1567)
                     /locus_tag="IVD26_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAP6080412.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1571..2431)
                     /gene="rlmB"
                     /locus_tag="IVD26_002489"
     CDS             complement(1571..2431)
                     /gene="rlmB"
                     /locus_tag="IVD26_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAP6080413.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2424..2819)
                     /locus_tag="IVD26_002490"
     CDS             complement(2424..2819)
                     /locus_tag="IVD26_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP6080414.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2816..4228)
                     /locus_tag="IVD26_002491"
     CDS             complement(2816..4228)
                     /locus_tag="IVD26_002491"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAP6080415.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4225..4761)
                     /gene="cysE"
                     /locus_tag="IVD26_002492"
     CDS             complement(4225..4761)
                     /gene="cysE"
                     /locus_tag="IVD26_002492"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAP6080416.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(5083..6543)
                     /locus_tag="IVD26_002493"
     CDS             complement(5083..6543)
                     /locus_tag="IVD26_002493"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAP6080417.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6713..7861)
                     /locus_tag="IVD26_002494"
     CDS             complement(6713..7861)
                     /locus_tag="IVD26_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAP6080418.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIIGLTLGVVISTPLYNM
                     EIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQLLER
                     KSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSLKRV
                     RGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNLNKV
                     SEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVEDGQ
                     HYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7895..9265)
                     /gene="radA"
                     /locus_tag="IVD26_002495"
     CDS             complement(7895..9265)
                     /gene="radA"
                     /locus_tag="IVD26_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAP6080419.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9328..9855)
                     /locus_tag="IVD26_002496"
     CDS             complement(9328..9855)
                     /locus_tag="IVD26_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAP6080420.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2507 a         2210 c         1782 g         3366 t
ORIGIN      
        1 aatctcaggc tcgtttgctt tttaaactgc ttcagttaaa aattcgatct caactgtccg
       61 agtaagtaca tctgaatagc tgtaagatac tcgttcaaaa gaattttctt caggatccaa
      121 atcaacaacg aatactgaag gataggtttc tgttaaaacg ccgcggcgtt ctgtttgacg
      181 ctttcttcct gtctgagcaa ccaacatgat tgggctgccg atacgacctt ctaaatcttt
      241 cttgattgaa gctaaagttg ttggcataca gttcacctct actatcaact ataccacata
      301 tttttaaaat tttcaagttt accataaaaa aaaaagaaat gcaataaaaa taaataagaa
      361 gctcattaag atttttctaa attattcctc attataaaat ttcaagtgtt tttttatttt
      421 gagttttact ctcccgtaag cgctcattac ttgcttgtga tccattgcta aacattcagc
      481 catgtctaca aaatcaacgc cttgcatata ataatgaaaa attttagctt ctatttttga
      541 aaactggatt tcgcaatttt cgattgcttc ttttaataaa agatgctgaa tcgctaaagg
      601 ttcttgcaat gtgatctctg ctaaaaagtc tggtccttct gtctctattt tttggtcgat
      661 tgagacttca tctttttgat cacgacgctt cagcgcgttc tgcttcctca acagagaata
      721 gatttgattg cttataatgc ttttataata acttccaaag ctaacacctt tgcttttttc
      781 gtaagttctc aatgcctgat ataaagcgat ccttgcttct tgttcccaat cctcagaaac
      841 ataatttctt aaataatagg tgtttttcaa acgtagtaaa agtggaaaat atttttgata
      901 cagggcagca aatgcttctt cgtcaccatt acgtgcagcg cgcaataact cctcagacat
      961 aaaataattc ctccataaat tcgtttatgg aggaatctta tcatcaatga ttcatcgaac
     1021 tgattagaac gatatgttat ttattttttc tcattaaatc gtccaatttt tgggacaatt
     1081 tttttaactg ctcttcattc catggagaat tacgtcggaa atcaataaaa tgcatatctt
     1141 tattttcttg ggctattgtt ttttccgttt tttttatcgt cttatataat tcataagcag
     1201 aagttcgtaa tgctccttgg gaaaagatca tccactgttc tgctaaatcg cttgtcgcca
     1261 ctgtcacttg tgtcaaacgg tcattcagct gaccagcgat tctctcgata taactgtcag
     1321 ccgtttcgtc ttctttcgta aaaacaacat ccaactggta tttcttataa ttttgttgga
     1381 tgcccggaac tagttgggca tcgaagacaa cgatgacttc cattccttca tatttcgcat
     1441 aatttgataa acgatgtaaa agagcttctc ttgcatccgc cattttgtcc tgctttttaa
     1501 gctggacaag ttccggccac gaaccaatca tgttgtagcc gtctacaatc aacagctgtt
     1561 ttttcatggt ctactccccc tgacgttggg aaaaagcctg atacataagc aaaccagcag
     1621 caacactggc atttaagctc tggacgtgcc cggtcatcgg gatcgtcagc aattcatcca
     1681 tttctttttt caatcctgga ctcattcctt tgccttcatt accaatgact aaagcaattg
     1741 atcctttggc attccatttt tggaagtttg tgccggtcat atctgtgcca aatacccaaa
     1801 atcctgtttc tttgagctgt tgcacagctt gtaccaaatt cgtcacgcgt gcaacaggga
     1861 catgttcgac tgccccagtg gaagtctttg ttacgatagg tgtgattcca actgctcggt
     1921 gttttggtat gatcacacca tcgacgccac ttgcgtctgc tgtccgtaaa atcgacccaa
     1981 aattgtgtgg atcttcgatg ctatccaaaa tcaaaaagaa ggggtcttct tttttctctt
     2041 ttgttcgttc aatcagttgg tcaagggata aatattcata aggtgtaatc gcaagaacga
     2101 ctccttgatg cacgccgtga tcgctcaaag tttctaattt ttgtttagga acccatttga
     2161 ctggcacagc ttgttcacgt gcgatttctt tcagttcttc tactttttct cctcgtgaat
     2221 cttcttgaag aaagagttta ttccctcgcc cttgttgtag cgcttctact gcggcatggt
     2281 gcccaaagac gaaattatct tctaatgctt cttcattttg atcagaaact gactgatttc
     2341 gtccagtttg ctttttattt gaatatctat tttgtttttt gtcttcaaat ccacgtttcg
     2401 attgatgttt gtttgttctt tctttaccca tttttttcac caactttctg aatacaccag
     2461 cggatcaatt cttccatccg ctcggtttgt tttgtcaaat gcagatagcc catgagcgct
     2521 tcgaaccctg ttgcgacccg atacgtcgta acatcagcat tttttgcgct cgtatggctt
     2581 ttagcatttc ttcctctgcg ataataaagt tcttcttctt ctgtcaaaag atgttcttcc
     2641 agcatttgct gaatcaaaaa ggcttgtgca ttcgcagaaa cataattcgt tgccgcacga
     2701 tgcagcttat tgggttttgt ttctccttga tcaatcaggt ggtcacgaac atagatttcg
     2761 taaatcgcat ctccaacata agccaaggct aaaccgttca attgtgtgta atctctcatg
     2821 cttctcttct ccatcgggtt ccttgcggtg tatcttctaa taagatccct ttttctttca
     2881 acaaatcacg aatttcgtcg cttcggacaa aatcacgatt gcttcttgct tgatttcgtt
     2941 cttcgatcaa ttgttcaatc tcttcatcta ataactcttc tgctgtaaat aaaataccga
     3001 agatcgaaag ccattgcgag aataaagctt ctccttgtgc caagacagcg gcagaaactt
     3061 tcggctggtc tagataagtg ttcagccact tagcaagctc atagaccact gtgatcccat
     3121 ttgctgcatt aaaatcatcg tccatttctt cgatgaatcg ctgttctaaa ttttctaaca
     3181 aagcgatttt atccgcatca tctgccaaat tctctgaggc agtttcttgg cggaatttca
     3241 aattgtcaaa cgtattcttc agtcgttgta aattggtggc tgcttctttc atcgtcgttt
     3301 cactgtagcg gatcggacga cggtattgtg tggtcgccat gaagaaacgc aagacttgtg
     3361 gatcaacgtt tttgatcatt tcatgtacag tgatgaaatt ccctagagat ttactcattt
     3421 tttcatcgtc ttcgccaatc gttacatagc cattgtgcat ccagtaatta gcgaattttt
     3481 tccctgtttt cgcttcactt tgtgcgattt cattttcatg atgaggaaat tctaaatctt
     3541 gcccgccacc atggatatcg atcgtttctc ctaaatgttt tgttgccata acggaacatt
     3601 caatatgcca accgggacgt cctttgcccc atggtgaatc ccaagaaatc tcgccaggtt
     3661 ttgcttgttt ccataaagcg aaatctaatg ggtcttcttt ttgctgctgt tcttcccctg
     3721 tacgctgact tgctccgact tccagttcat cgatggattg gtcacttaat ttcccataat
     3781 tttcaaattt acgggtacgg taatacacat cacctgaaga ttcataagca tagccttttt
     3841 caaccaacac ttgaataaat gctaaaatat ctggcatatg atccatgact cttggatgca
     3901 gtgtagcagg ctcgacattc aacgctttcg tatcttcttc aaatgctcgg atgaaacgat
     3961 cagcaacttc tggtgctgta atacctaatt cgtttgctgt acggatgatt ttatcgtcta
     4021 catccgtgaa attcgatacg aaatcgactt tatagcctcg atattcaaaa tagcgtcgaa
     4081 ttgtatcgaa agcaatggtg ctacgagcat ttccgatatg gatataatta tacacagtcg
     4141 gtccgcagac atacataccg acatgtccct tttgtatagg gatgaattct tctttttttc
     4201 tggtcaatgt attgtagatt tttatcattc tgatctcctc actttttctc ctttgattcg
     4261 aacgactttt gctggtactc ctaccgctgt agcgtcgtct ggaacatctt tcaacacaac
     4321 ggcacctgca ccgattttgg cgttttttcc gatcgttacc ggtcctaata tctgcgcatt
     4381 cgcagagagc atggctcctt gtttaacagt tgggtgtctt ttacccgttt cttttcctgt
     4441 gccgcctaat gttacgccat ggaataaaat cacatcgtcc tcgatttctg cggtttcgcc
     4501 aatgacgatt cccattccat ggtcgatgaa cacgccagtt ccaatcgttg ctcctggatg
     4561 gatctcaaca ccagttagga aacgccagaa ttgagcattg atcttcgcca ataaaaagag
     4621 ccggtgctga tataaaaaat gagagaaacg atgccaaaac aaggcatgaa aaccagggta
     4681 tgtcaaaacg atctcagctg tcgaacgtgc agccggatcg tttctctttg ctgcatcaat
     4741 cgctcgggta aaccaactca tgactttcca ctcctttcgt aagaatttta tgtaggaaat
     4801 catcttctta taaagaaaag aagcgccttt taaataagtt tccttatcaa aagacgcttt
     4861 ccgcgtggtt ccacttttct tcataatcaa tgattatctc tgacagctaa cgcctgttat
     4921 acgttcttgg ctactttgtt tcctataaaa cagtttttcc tgttttctgt gtttcgccaa
     4981 gaccactccc agaggcattt cggcaaccat tcattgatac cttgcaccac ccggtatctc
     5041 tcttgtaatg atcagctgct tacttttttc tgttcatcgt gtttagttca gtacttgatt
     5101 taaatgtgct aatgattttt cacgaccaag caattcgatc gtttcaggca attctggacc
     5161 atgcatttgt cctgatacag ctacacggat tggcatgaaa agattttttc cttttacgcc
     5221 agtttctttt tgaacagctt tgatggcagc tttgacagtt ggagcatcta ctacttccat
     5281 ttgttctagc tgtgctttga atgcgtggag aacagtagga actgtttcac cagcaagtac
     5341 ttcttttgct gcttcattca atacaggatg ttcattgaaa aatagcgtag acagatcaac
     5401 gatttctgca gcatagctca tttgaggttg atacaggcta acgatcttct tcacccattc
     5461 gattgtcttt tcatctgggt tttctgctac acgtccatca gcgattagat aaggcagaca
     5521 catgtcagta aatgcatcta gatccattgc tttgatgtaa tggttgttta cccattgcag
     5581 ttttttcgca tcgaaagctg cgggtgattt acttaggcgt tttggatcga acattttgat
     5641 caattcttgg tgttcgaaga tttcgtcttc gcccacaggt gaccagccca ataatgcaat
     5701 aaagttgaac attgcatctg gtagatagcc taattcgcga tattgttcga taaattgcaa
     5761 gattgattcg tcacgtttgc ttagtttttt acctgtttca ctgttgatga tcaatgtcat
     5821 atgtccgaag gttggtggtg tccagccaaa tgcttcatag atcatcagtt gttttggtgt
     5881 attggcaata tggtcatctc cacgtaaaac gtgagtgatt ttcatcaaat gatcatcgac
     5941 cgcaacagca aaattataag ttggcatacc atcgcgtttt tgtatgacaa agtcgccacc
     6001 gatattatcg gattcgaacg aaatagcgcc tttcaccata tctgtaaatg cgtattctgt
     6061 attgcgaggc acacggaaac gtacaacaga ttctagacct tgtgcttctt tttctgcttg
     6121 ttcttcaggt gtcaagttcg cacatgttcc tgcgtaatga ggcatttctc ctcttgcgcg
     6181 ttgtgcttcc cgttctgctt ctaattcttc ttctgtgcaa tagcatttgt atgctcgatt
     6241 gctagcaagc agctgatcaa tcagcggttg atagatttct ttacgttcag attgacggta
     6301 agggccgtat tctccaggat tttcaggaga ttcatcccaa ttcattccca accaagcaag
     6361 gttttccaac tggctttttt cgccatcttc gatattacgt ttttggtcag tatcctcaat
     6421 acgaataata aagtctccat cattgtggcg ggcaaacaaa taattgaata atgcagttct
     6481 tgcatttcca atatgcaggt gcccagttgg acttggtgca tagcgtacgc gtactttcgt
     6541 cattttcttc ctcttctttc aaactagact ttgactaaca gcaaaaattc cgtcagttac
     6601 ggcttctcaa atatcattta tttaaagcca ctcagcacaa attttacctt ttctaaggta
     6661 aatagtaaag ccaactggtt gaatttcctt accagttggc tgaatttctt ttttattttg
     6721 attgtttagt ctttttctct gtctcttttt tattgtcgat tcctcgtcct gcatgtgcag
     6781 gtttagcaaa gatcatgcgt ccagcagctg tttgaagggc acttgttaca acgacttcga
     6841 tacgttcatt catgtaatgc tgtccatctt ctacgacaac catcgtgccg tcatcaaggt
     6901 aggctactcc ttgttggcgt tctgtcccgg cttttactac tagaacattc atcgtttcac
     6961 cagggatgac gactggtttt acggcatttg ccaacgcatt gatattaaga acaggtacat
     7021 tttggaattc agagacttta ttcaagttat agtcattggt tacaatgaca ccatctaaaa
     7081 gcttagccaa tttgatcaat ttgctgtcta cttcactgat atcttcaaag tctccatcgt
     7141 acatttcgac agatataccc tcttcttttt gcaaggcatt taggatatct aatccgcgac
     7201 gaccacgcac acgtttcaaa ctatcccctg agtccgcgat gtattgtagt tcgtaaagaa
     7261 caaaattagg gatcatcaag gttccttcta agaatccagt ctttgtaata tcataaatcc
     7321 gaccgtcaat gatcacgctt gtatccaaga ttttatattt atggaaattt tctcctgatt
     7381 ttcgttctaa cagttgactc tcaacttgac tagctgtttc ttgctcgatt tttttgcttc
     7441 gtgaaccaaa aactttcttc cattcttcga ttcgtgtcgt tcccattctc aatcccagat
     7501 agcctaagat gatcatcagt aaaatcggca atacactatt gacgaatgga atttccatat
     7561 tgtaaagagg ggtcgagatc acaacaccta aagtcaatcc gatgatcgca ccgaagagaa
     7621 gataagtcaa gctgacctca cttagttttt gttctacttg tttgataata gctgagatat
     7681 gtttggccaa cagcaaagat aataaaaaga aaataagtgc gcctaacagg ctgttggtaa
     7741 atgtattatt cagccatccg tttgactgtt gaccgattgc ctgccaagct gagggtaaaa
     7801 atgaaatacc caagcttgcg ccgacaatga tcatcagcaa agtaatgaca cgtttttgca
     7861 tcgtttttcc tccgtttcga caatcattta ttagttagcg gaacacacgc ttcaacgttt
     7921 cagccaaagt tgctactcca actatctcga ttccttttgg cgcttcccag ttacctaagt
     7981 tgtttttagg taggtatact tttgtgaagc cgagtttttg gacttctttg actcgttgtt
     8041 caatatgact gacacgtctg atttctccag tcagtccaat ttcaccgatg aaacattccg
     8101 ttggctgtgt tcctttttct ttatagcttg aagcaatact gacagcgata gctaaatcaa
     8161 tcgctggttc atttaatttt accccacctg cagcttttaa gtaagcatct tgattctgaa
     8221 gaagcaaccc agctcttttt tccagcactg ccatgatcag agatacccga ttgaaatcaa
     8281 gacctgttgt tgttcgtttg gcatttccga acatagtagg tgtgactaat gcttggatct
     8341 ctaccaaaat tggacgtgtc ccttccattg ccacaacgat agcagagcca gttgcaccgt
     8401 ctaggcgttc ttctaagaaa atctgtgaag gattagcgac ttcttccaat ccatgctcat
     8461 gcatttcaaa aatcccaatc tcattcgttg agccaaatcg gttttttact gctcgcaaaa
     8521 tccgaaaact atgatgttgt tcaccttcaa aatataacac cgtatccacc atatgttcta
     8581 acattcttgg gccggcgatc gagccttctt tggtaacatg accgacgata aaaatggcta
     8641 tcccatttgt tttagcgatt ttgagtagtt ctgcagtggt ttctcttact tggctgacac
     8701 ttcctgccac acttgtgatg tctggctgcg tcatcgtttg gatggaatca atgataacat
     8761 aatcagggga gatatgttcg atggcacgac tgatttcgtt catatctgtt tcagcgtata
     8821 gataaaattc tgtgttgata cttccgaggc gttccgcgcg taattttatc tgctctgcgc
     8881 tttcttcgcc ggatacatat aagacttttc cgcctatggc tgctaattgc tgagaaactt
     8941 gtaacagcaa agtggatttc ccgatacctg gatcgccacc aatcaagacc atagaccctg
     9001 gcaccacacc tccgcctaac acacggttca gttcttctaa ttttgttttg atccgaggtt
     9061 cttttttagg gacgacgtct gcgatttttg ttggttttgc tttttctcct gtcaaacttg
     9121 tccgagttct gcggtccgtt gtatcttgtt cgatttcttc gaccatcgta ttccattttc
     9181 cgcaatttgg gcagcgtccc aagaacttag gcgacacata cccgcaattt tggcaaacaa
     9241 attgtacttt tgattttttt gccattgtac cgcctccttt tatcctaatc atgagacatt
     9301 aaatcaagct taagtatctt taacgtttta tttactggaa gaaccaaatc cgccttgacg
     9361 ttgagcagtc gtttgatctt gatctgcttt taaaaacggc aaaaagatcc cttggccgat
     9421 acgctcgcct tttttgatca ctacatcctt gaaaccaaag ttggtgaatt ggaacatgat
     9481 atggccttca tttgcctcat tattgtaata atcactgtca atcacaccta ctccgtttgt
     9541 caacactaaa aaccgcttca acggattgct tgaacggtta gcaagctgca aaaattcatc
     9601 ttctcccatg taagctttga ttccagtagg cacgagggtt ggtttcaatt gtttttcatt
     9661 ttctgataca tcttttttca atccatctgc gactgtttcc aacccctttt tccagcctgc
     9721 tttccagata cttggaatca cgacctcttc tgctgcttca aaatcatagc cagcagcatg
     9781 atgtgtagcg cgctgcggta gattgatatt ttgatcttta tatttagaaa taacttcaaa
     9841 tcctcttttt ctcaccggtt ttcct
//
LOCUS       DACBYO010000102         9776 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.102, whole genome shotgun sequence.
ACCESSION   DACBYO010000102 DACBYO010000000
VERSION     DACBYO010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9776
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.102"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(78..2198)
                     /locus_tag="IVD26_002497"
     CDS             complement(78..2198)
                     /locus_tag="IVD26_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP6080421.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2428..3606
                     /locus_tag="IVD26_002498"
     CDS             2428..3606
                     /locus_tag="IVD26_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAP6080422.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3622..4380
                     /gene="aroD"
                     /locus_tag="IVD26_002499"
     CDS             3622..4380
                     /gene="aroD"
                     /locus_tag="IVD26_002499"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAP6080423.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4403..4888
                     /gene="ybaK"
                     /locus_tag="IVD26_002500"
     CDS             4403..4888
                     /gene="ybaK"
                     /locus_tag="IVD26_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAP6080424.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4959..6212)
                     /locus_tag="IVD26_002501"
     CDS             complement(4959..6212)
                     /locus_tag="IVD26_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP6080425.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6328..7677
                     /gene="gdhA"
                     /locus_tag="IVD26_002502"
     CDS             6328..7677
                     /gene="gdhA"
                     /locus_tag="IVD26_002502"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAP6080426.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7789..9135
                     /locus_tag="IVD26_002503"
     CDS             7789..9135
                     /locus_tag="IVD26_002503"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAP6080427.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9443..>9776)
                     /locus_tag="IVD26_002504"
     CDS             complement(9443..>9776)
                     /locus_tag="IVD26_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP6080428.1"
                     /translation="KGWDYYQSTYVGKDYYAVVKAPMPAETDIKADNGEVIGRGFKYN
                     VDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKASEKRIIEKKVITSDKVPSS
                     VKEKLGLS"
BASE COUNT         3115 a         1778 c         2007 g         2876 t
ORIGIN      
        1 tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctaatttt gtcgctgctc
       61 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
      121 gtttgcgttt tataaagatc aacagttgat tgtcccttgt gttcactaaa gacactagtt
      181 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
      241 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
      301 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
      361 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
      421 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
      481 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
      541 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
      601 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
      661 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
      721 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
      781 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
      841 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
      901 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
      961 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     1021 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     1081 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     1141 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     1201 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     1261 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     1321 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt caagctggag accattctca
     1381 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     1441 ttttttcctt tagcgagccc gaacaaatca tcatttggtg ctgcataatg ttcttttaca
     1501 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     1561 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     1621 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     1681 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     1741 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     1801 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     1861 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     1921 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     1981 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     2041 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     2101 aaataggcaa aaatcgtttt caaccaaagt aaaacaacta gtaaagaaaa aaatccgagc
     2161 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     2221 cttaatcaca gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta
     2281 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     2341 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     2401 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     2461 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     2521 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     2581 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     2641 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     2701 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     2761 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     2821 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag
     2881 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     2941 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     3001 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     3061 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     3121 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     3181 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     3241 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     3301 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     3361 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     3421 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     3481 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     3541 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     3601 cattagaagg agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga
     3661 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     3721 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     3781 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     3841 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     3901 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
     3961 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
     4021 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
     4081 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
     4141 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
     4201 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc
     4261 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
     4321 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
     4381 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
     4441 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
     4501 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcata tatttaaaac
     4561 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
     4621 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
     4681 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
     4741 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
     4801 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
     4861 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
     4921 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
     4981 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
     5041 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
     5101 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
     5161 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
     5221 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
     5281 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
     5341 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
     5401 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
     5461 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
     5521 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
     5581 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
     5641 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
     5701 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
     5761 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
     5821 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
     5881 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
     5941 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
     6001 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
     6061 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
     6121 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
     6181 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
     6241 tctgaagaaa gaaaacagaa aaaatgtttt gagccaaaag agaaaatgag ctaaaatgag
     6301 ggaagataag caaaggagcg tggaacgatg acaaacgcaa cagaatatgt tcaagcaatt
     6361 caagaaaagc tacatcaaaa ggatcaaggg caagaagaat ttttacaagc aatcgatgaa
     6421 ttcatgccca cggttatgtc ttttttggac actcatcccg aatatatcga aaagaatatc
     6481 ttagaacttt taacggaacc agaaagagtt attcaatttc gagtgccttg gcaagatgat
     6541 gaaggaaact ggcgagtaaa tagagggtac cgtatccaat acaactcagc tatcggccct
     6601 tataaaggtg gattgcgctt ccatcctagt gtcaatctaa gtatcttgaa atttttggct
     6661 tttgaacaga ttttcaagaa tagtttaacc ggtctgccaa tcggtggagg aaaaggcgga
     6721 agtgacttcg atcctaaagg aaaatctgat aatgagatca tgcgtttttg tcaaagtttc
     6781 atgctggaat tgtcaaaaca tatcggccca tcgattgatg ttcctgcggg agatatcggt
     6841 gtaggagcta gagaaatcgg ctatttgttc ggcgaatata aacgattgaa aaaatatgat
     6901 actggtgtgt tgacaggtaa acctttggat ttttggggaa gtaagatacg tacggaagct
     6961 actggttatg gattagtgta ttatgtcaaa catctattga acgaagaaaa agattcattt
     7021 aatcaaaaaa cagtttttgt ttccggaagc gggaatgtag ccatttatgc aatcgaaaaa
     7081 gtgcaagagc taggcgggaa agttgttaca tgttcagatt ctagcgggta catctatgat
     7141 ccagaaggaa tagatgtgaa actattgaaa gaagtcaaag aaatcaatag acaacgtttg
     7201 acggaatacg caaaccaacg tccttctgct atttatcatg ctggagaatc tgtttggaca
     7261 ttgaaagaaa aagcggatat cgctttgcca tgtgctactc aaaatgaaat agacgaaagc
     7321 ttggccgaaa tcttagtaga aaatgggatc aaaatcgtag cagaaggcgc taatatgcca
     7381 tgtacagtaa aagctgtttc tgttcttcat gaagcaggcg tgtggtattg tccaggaaaa
     7441 gctgctaatg ctggaggagt agcagtatct gctttagaaa tgagtcagaa cgcccagcga
     7501 ttgacttggg aaagagagca agtggatgag cagctggatc aaatcatgga aacgatttac
     7561 catacgtgtc gccaaacagc agccgagtac ggcgacgaaa aaaatctgct tcttggagca
     7621 aatgttgctg gatttgaaaa agttgccaaa gcaatggcag cagaaggttt agtttgaaaa
     7681 atgaaacttt cttggaaata ttgtcagcat tttgtttatt tgcttgaaaa ataataaaaa
     7741 aaaacgtaaa gtattacctg tagagtaaac ctataaggag gagaacaaat ggcacacatt
     7801 cattttgact attcaaaagt agcaccgttt gtcaacgaac aagagttagg gtacatgcaa
     7861 agccaagtaa cagcagccca caacgaatta cgggaaggta ctggcgcagg aagcgacttc
     7921 cgcggctgga tcgatttacc aacgaactat gacaaagaag aatttgcacg tatcaaagaa
     7981 gcagctaaaa aaatccaatc tgattctgaa gtattagttg ttatcggtat cggtggttct
     8041 tatttaggcg ctcgtgcagc gatcgacttc ttgaatcaca cattcttcaa tttattagat
     8101 agcaacacaa gaaaagcacc acaaatcttc tttgccggaa attcaatcag ctcaacatat
     8161 attgctgact tgatcgaagt aatcggtgat cgcgactttt cagtaaacgt tatttcaaaa
     8221 tctggaacaa ctactgaacc agcgattgcg ttccgtgtat tcaaagagct tcttgttaag
     8281 aaatatggac aagaagaagc aaacaaacgt atctacgcta caacagataa agcaaaaggt
     8341 gcagttaaag tagaagcaga tgcagaaggt tgggaaactt tcgtgattcc tgatgacatc
     8401 ggcggacgtt tctctgtatt aactgctgtt ggtttgttac caatcgctgt tagtggtgca
     8461 gatatcgatg cattgatgca aggtgccgct gatgcaagca aagcatactc aagcgacaaa
     8521 ctagaagaaa acgaagctta ccaatacgca gcaatgcgca acattcttta ccgtaaaggc
     8581 aaagtaactg agttgttgat caactatgaa ccaggaatgc aatacttctc agaatggtgg
     8641 aaacaattgt atggtgaatc tgaaggaaaa gaccaaaaag gcatctatcc ttcaagcgca
     8701 aacttctcaa ctgatttgca ctctttagga caattcatcc aagaaggacg tcgcaatatt
     8761 tttgaaacag ttgtgaaggt tgaaaaacct cgtaaatcaa tcacaattcc tgaacaagca
     8821 gaagatttag acggtctagg ctacttgcaa ggaaaagaag tggacttcgt aaatacaaaa
     8881 gcatttgaag gaacattgct tgctcataca gacggtgacg tgcctaactt gctagtcaaa
     8941 attccagaaa tggatgctta tacattgggt tatacaatgt acttctttga aattgctgta
     9001 ggtatttcag gttacttgaa tggaatcaac ccattcgacc aaccaggtgt agaagcttac
     9061 aagaaaaaca tgttcgcact tctaggcaaa ccgggctttg aagatcttgc taaagaattg
     9121 aacgaacgcc tgtaagataa gggtttttcg ctagatttaa ataatcagtg atagaaacat
     9181 gttcgcttta aaatgaaaac tggtacccat ttaggtactc aaacatactg catcgtttat
     9241 tcagaataag gggctgtgac aagacgtttg tcacagtccc ttgtttgtat agaaatcgat
     9301 tgattgcctt gctctttagt ttgttttagg actttaagaa cagtgaggct gacttcgaag
     9361 gttaattctg tttttttgtt ttctagaatc agtaagcaaa aaagcactca cttcgagtgc
     9421 ttttttgcga tatattctta gcttaagata ggcctaattt ttcttttaca gatgagggta
     9481 ccttatcgct ggtaattact tttttctcta tgatccgctt ttcgcttgct ttcaactgca
     9541 agatcgttcc ttcggtgtaa gcagaaccat tggcagagtc accagaagta atgacatcga
     9601 aatctaactg tcttttttca ccgttttcag cataagcatc tacgttgtat ttaaaacctc
     9661 ttccaattac ttccccatta tctgctttga tatcagtttc tgcaggcatt ggagctttga
     9721 ctaccgcata ataatcttta cctacataag tagactgata gtagtcccaa cctttc
//
LOCUS       DACBYO010000103         9549 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.103, whole genome shotgun sequence.
ACCESSION   DACBYO010000103 DACBYO010000000
VERSION     DACBYO010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.103"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            14..436
                     /locus_tag="IVD26_002505"
     CDS             14..436
                     /locus_tag="IVD26_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP6080429.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(602..1795)
                     /locus_tag="IVD26_002506"
     CDS             complement(602..1795)
                     /locus_tag="IVD26_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6080430.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            2019..2396
                     /locus_tag="IVD26_002507"
     CDS             2019..2396
                     /locus_tag="IVD26_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP6080431.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2384..2722
                     /locus_tag="IVD26_002508"
     CDS             2384..2722
                     /locus_tag="IVD26_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP6080432.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            2712..2825
                     /locus_tag="IVD26_002509"
     CDS             2712..2825
                     /locus_tag="IVD26_002509"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6080433.1"
                     /translation="MEADNSNTLALLLEKLIRDYPSVQFHIHSGTSDDITE"
     gene            2856..3299
                     /locus_tag="IVD26_002510"
     CDS             2856..3299
                     /locus_tag="IVD26_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAP6080434.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            3561..4376
                     /locus_tag="IVD26_002511"
     CDS             3561..4376
                     /locus_tag="IVD26_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6080435.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            4386..5048
                     /locus_tag="IVD26_002512"
     CDS             4386..5048
                     /locus_tag="IVD26_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP6080436.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            5253..6917
                     /gene="alsS"
                     /locus_tag="IVD26_002513"
     CDS             5253..6917
                     /gene="alsS"
                     /locus_tag="IVD26_002513"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAP6080437.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            6930..7640
                     /gene="budA"
                     /locus_tag="IVD26_002514"
     CDS             6930..7640
                     /gene="budA"
                     /locus_tag="IVD26_002514"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAP6080438.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            7770..8267
                     /locus_tag="IVD26_002515"
     CDS             7770..8267
                     /locus_tag="IVD26_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAP6080439.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            8452..8712
                     /locus_tag="IVD26_002516"
     CDS             8452..8712
                     /locus_tag="IVD26_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080440.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(9074..9313)
                     /locus_tag="IVD26_002517"
     CDS             complement(9074..9313)
                     /locus_tag="IVD26_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080441.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT         3238 a         1578 c         1897 g         2836 t
ORIGIN      
        1 aggaggagaa aatatgcaga cttttttaac aaaagtttct caaaagaaaa ttaaaatgat
       61 tcatttactg cttgaaacag aacgttggtg ttcaatagaa gaactacaaa acgaattgaa
      121 ggtatcaagt aagtctatct tgaattatct aacagattta gaagaattgt tccaaaaata
      181 tcctgataag gtcattttga agaatgagaa taatcggcgc ttttctatgg aaaagcagga
      241 gaacttccca atctacatta tttatcttca tttctacaga aaatcatata attatcattt
      301 gattgaattc atgtatcaac atcctgagaa aaatttggaa gattatgcag acgctcaata
      361 tacgagtgta tccacagttt ttcgttatgc taagttatta gtaaagtact ttgaaatgac
      421 ggacgtcaaa gaatagtagc cgccagatag aaggaaatta gcagttgaaa aagctgccct
      481 gcatcaagta atacgaccag ccaaacggaa acagtgtctc atgtttttga tttggctggt
      541 cttattaccg cagatgcaag cttttgccac acctctttct tgtcatttac agactcaact
      601 atcaatgctg caagctttcc cttaatgctg taacaccagt aagagttgtc aagaccagca
      661 gactgactag gtaaataccg ctcaaaaaca agattacggc agttaaacta taatgatcca
      721 tcaagaaacc gatgacgata gaagaaaaac caccaacagc tcgtccaagg ttcataatga
      781 aattattcgc cgtcgcgcgg atttctgttg gatacaaact actaatcact gcgccatatc
      841 caccatacat gccattgata aagtagccga ctatcacagc ggctgctacc aaactccact
      901 ggctatgggc taacacaagt agatagacag ataaggatga acaaattaaa aacaaagaaa
      961 aggctagttt aggccccaat ttatccatga ttatgccaaa agtcatcatc cccaaagaca
     1021 tgcctaaaat agtactgacc atccacaatg aagacccaga aaccgaaagc cctaatcgat
     1081 tttgcataat tgaaggcagc caattcatta acccaaaata gccggcaatt tggacagtta
     1141 ccatgatact aaggccacat gtttgccaag caagatgttt tgattcaaac agtctgctaa
     1201 gtttggtttt cttttcggca gattgtacag atttgaattc ctttggttca gtcaagccgc
     1261 gacgaatgaa caagaccatc aacaccggca gtacacctac gacatacaac atcttccaac
     1321 caaacgttgg aatgatcaca gcagctaaaa tcgcagccaa agccgcaccg acctgcgcac
     1381 caataccagc aaccgaagaa gctcgtccaa tttgtttttt tgaaaaactt tcggaaatca
     1441 aggacataca cgccccgtat tctcctcccg ctcctacacc tgcgataaag cgaaagagat
     1501 aaaccaagta gatgtttgaa gcaaaataca tcaataaaga agcaatcgaa aacagaagga
     1561 ccgtttgaga aaatactttc acacgtccat atttatcagc tatgatgcca aaaaaaatac
     1621 ctccaatgag catccccaaa ttagtgatcg ttgaaatgaa acccgcttgc gtaccactaa
     1681 tatgaaaaga agtaatcatt gaagataatg aaaaagctaa aaacataata tccatattct
     1741 ctaaagcaat tcccgccgat gtcgataata ataactttcg ctgatacgtt gtcattttta
     1801 tacccctttt cctaaaattt ccctaaattg ttaaaagtat atccaaaaaa gaataaaaaa
     1861 acaagacttt tttatttgaa ataatacaca aacaaccgat atagataatc cagcttagtt
     1921 ttaatagaaa tgagtattga cttggagtac acttaaagtt gtagaataaa taaaatacat
     1981 aagtaaagtg gcaagaaatt aagagaaaga gtgatcagat gaatatcaaa caagtcagtg
     2041 aagaaaaggg catttcggcc gatacattgc gctattatga acgaatcggg ttgattccac
     2101 cagttaatcg gacaaaaggc ggaatccgtg attatacaga agaagaccta aaatgggtcg
     2161 actttacgat ctgtatgcga aatgccggat tatcgatcga gtctttgatt gaatatattc
     2221 gcctatctag cgaaggagaa gcaactgtat ttgagcggcg taagcttttg attgaagaaa
     2281 gtgaactttt gacgaaaaaa attgctgaaa tgcaagaatg tttggaacgt ttacaaggaa
     2341 aaatcaagaa atatgatcgt gtgttatcta gaaataaaat ggaatgtatc aagtaaaaaa
     2401 atcaaggagc atcgctatgg agttacgctt actaaaatat ttttggacaa ttgcagaaga
     2461 aggaacaatc tctcaagccg cagaagttct acatcttaca caaccaacct taagccgaca
     2521 actgaaggag ttagaagagg aactaggaac agaactgttt gtacgcgaaa accgcaaaat
     2581 gatcttgaca gaagcaggtt attttctaaa aaagccgagc agaagaaatt ttagatttaa
     2641 cgaatcaaac cactcaagaa ttcgagaaca gaaaaaaaca attattcagc ggccgattta
     2701 cgatcggctg tgtggaagct gataattcga atacattggc actattacta gaaaagttga
     2761 tccgtgatta tcccagcgtt caatttcata tccacagcgg aacaagtgat gatatcacgg
     2821 agtgactaga aaaaagcctg ttagatttag cgattttgct agatccagta gatacagaga
     2881 aatacgaaac gattttgtta ccaagaaagg aaaaatgggg attgctcatt ttagaaaatt
     2941 ctgttttagc aaaaaaagac gtgataacaa aagaagactt tgcgaatgta cctcttttga
     3001 tctcaaagcg tccagaaata cagcgaatgt ttgctgactg gttaggcata aaaaaggagc
     3061 agttgctgat cacaggaacg tacaatttga ttttcaatgt atttgcgcta attgagaatc
     3121 aggtaggtgc tgctttagtc atagaaggtg ctgtaagtca tctttcaaag cgagtgacat
     3181 tcgttccgct tgacccaatg attgaaacga actgcatgct agtctggaaa aagaatcgga
     3241 ttttatcacc tgtagtcaat gaattgattc accgtttcaa agaagctttt gaacagtaat
     3301 aagtatctct aatcgaagaa atttcaatac aaaagcgaga cgtatgacag tcttgctttt
     3361 gtattttttc atttttaaat caaaaaaaat aaagagattt acataacttg ttaaataagc
     3421 gcttacaaac ataagaagaa cggaaatgaa tcagctataa taaccgttgt tctggattgt
     3481 aatcattaca aagaaatgaa gattataact ttggaggtgt tcgaaatgaa agaaaaaaag
     3541 caaaaattcg ttcaaaaaac atgcccttta ttcaatggtt gggtatgatt ctgctgattg
     3601 tattagcttt attgacgatc attccttttt tatggatggt ttctgcttca ttcaaagcaa
     3661 ataatgaagt gttcacgatt ccgattcaat ggatccctaa aacttggcat ttagagaatt
     3721 atctggttat ttggtctcgt attcctttag tgacattttt taagaataca gcttttttaa
     3781 gcgttgtgat cacgttgatt cagttgttta cttctagttt tgctgcttac gggttttcta
     3841 aactaaattt taaagggcgc gatattttat ttttagcata tatcggcacg attgctgtcc
     3901 cttggcagtc ttatatgatc ccgcagttca ttatgatgag aaaagtgggt ttaacatata
     3961 cgttgtggtc gttggtgcta ttacaagcgt tcaatgcttt tggtgtgttc ttgttgaagc
     4021 aatactacag tagtatccca gattctttat gtgagagtgc gcggatcgat ggcttatcag
     4081 agtggggaat ctatcgcaag atcattttac ctcttacaaa accggcgatt gccagtttga
     4141 cgatcatcac attcgttaat acatggaacg attatatggg gccattcatt tatttgtctt
     4201 ctacggaaaa taaaacaatc cagttagggt tgaaaatgtt tattgggcta tttgatgcag
     4261 agtacgcatt aatcatggct gcctcagttg tttctgttct tcctgttgct tttatatttt
     4321 tagcgatgca aaaatatttt gtagaaggga tcgcttcatc aggaatgaag gaataggagg
     4381 tgattatgaa agagcagcgt tttgacaaaa atgtttatat ggaattcttt tattggttgt
     4441 atcaatcatt ggcaagtagc ctttgttttt ggtgtgtcaa tatcttgtat atagcagctg
     4501 cgttcctttt gtcgatagat ggaaggaatg tcttttcctt tattttttct ttacttttta
     4561 ttggtccagg ttgcatcgtg atgataggta tgacagaaga attagcaaaa gaaaaaagtt
     4621 tttcaccagt acgtttgttc ataaagacgt ttcgccaatt ttggctaaag ggattttttt
     4681 attggctatt tgcttggata gttagtgtga taatgatttt tgattgtttc ttttttatac
     4741 gtttttctta tggaaaatgg ttgattccgt tgtttgtttt acttgcttgt ttatcagttt
     4801 cctttagcat caactactgg tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag
     4861 ttctacggat agcgttctac tatacgttga aaaaatggta tgtgagttta ctagattttt
     4921 tactattgac aagtttgttt ctcttctttt tcgtaaagcc ccaatggtgt attctactag
     4981 gtccttctat cgtatttggt ttgatttact tcaacaatcg taaattgatg agaactatgg
     5041 atctgtagac tttataaatt gaaactttca attaagaatg acagttttta tgtaaaaact
     5101 gtcattcttt ttcatttttt gaaacatatg gctaaacaaa tgaaataaaa cgtgctatac
     5161 ttttgaatga aacaggttta gaaactgtat caattatttg tgattatttc taactaataa
     5221 ttaaaaataa agcataaaaa ggacgatgtt caatggacga aaaaatgaaa caaggttcga
     5281 aatctgtagt agaaagtttg attaatcatc atgttgatta tgtattcggt ataccaggtg
     5341 caaaaatcga tggtgtattt aatgaattag aggatcaagg tcctgaatta atcgtgactc
     5401 gtcacgaaca aaatgctgca tttatggcac aagcaatcgg acgtattaca ggagagccag
     5461 gagtagttat cgcaacaagt ggtcctggtg ctagtaactt agctacaggt ttggtaacag
     5521 cgacagcaga aggtgaccca gttttagcaa ttgccggaca agtaaaacga agcgatctat
     5581 tgaagttgac ccatcaaagc atggataatg cagcactgtt ccagccaatc acaaaataca
     5641 gtgcagaaat ccaagatcca gaaacaattt cagaagtgat tgccaatgct tatcgtatgg
     5701 ctaagagttc aaaaaaaggc gcgagcttta tcagtatccc gcaagatgta gtggatgcac
     5761 ctgtccaagg gaatgtcatc aagccattga gcgatcctaa attaggttct gcttctgcag
     5821 atgatatccg ttacctagct gaacgcatta gagaagcaaa actaccggta ctattagtag
     5881 gtatgcgagg atcaagtgaa aaagaaacgt tagccatcag gcaattagtt ggaaagacag
     5941 cattgcctgt tgtagagaca ttccaagcag ctggagtgat ctcacgtgaa ttagaagcgc
     6001 atttctttgg tcgtgtgggt ttatttagaa accaaccagg agatatgctt ttgaaacgaa
     6061 gtgatctagt tattgctatt ggctatgatc caatcgaata tgaagcaaga aactggaatg
     6121 cggaaaaaga tgcgcggatc attgtgatcg atgaagcgcc agctgaaatc gatcctttta
     6181 tgcagcctga aagagaattg atcggtgata tctcagccac tcttgattta ttgacaggtt
     6241 cattagagcc tcaacaagtg tcagaagatg caaaagaata tttagcatct cttcaagcag
     6301 aattaacgga gcgggacatt gttcaatcaa aaggagaagc aggtatcttg catcctttag
     6361 aagttattaa cacgcttcag tcaaaagtaa cagatgatat gactgttacc gtagatgtag
     6421 gtagtcatta tatttggatg gcacgccact ttagaagtta tgaacctcgt catttgttat
     6481 tcagtaatgg tatgcaaacg cttggtgttg cattgccatg ggcgatttct gctgcattgg
     6541 tgcgtccaaa tacacaaatc gtatcagttt ccggcgatgg gggattttta ttctctgccc
     6601 aggatttaga aacggcggta cgtaaaaaat tgaatatcgt tcatttgatt tggaatgatg
     6661 gacactacaa tatggtagag ttccaagaaa aaatgaaata tcagcgggcg tcaggtgtag
     6721 actttggtcc agttgatttt gtgaaatatg cagaagcttt tggcgctaaa ggaatccgag
     6781 ctacaagtgt agaggaatta gaaaaagctt tagaagaagg atttgcgaca gaaggacccg
     6841 taattattga tattccgatt gattaccgtg ataatgagaa attgggagaa acaatcttac
     6901 cagatcaatt ctattaagga agtgtcgaca tgactgaaaa aatcttatac cagcacggga
     6961 cattaggagc tttgatggct ggcttgatgg atggaacaga aacgattgct catatattag
     7021 aaaaaggaac tctgggattg ggaacattgc atgggcttga tggtgaagtc atctttttag
     7081 atggcgtagc ttatcaagga agatcagatg gctcagttgc ccaattagat ggaagtgaac
     7141 ttacccccta tgcagcaatt acagatttta cgccagatac tagtttttct gtctcaaaaa
     7201 ctgcagatgg agaacaattg aaaaaagaca tattagtaag agaagccggg gaaaacctat
     7261 ttttggcagt gaagataact ggattattca aaaatatgca catccgtatc atgccgaagc
     7321 aagaaaaacc ttacagaaga ctagcaaaaa tttcagagtc tcaaccagaa ttccaacaaa
     7381 gcaatgtcca aggaacatta gtcgggttct ttacgcctga attattccaa ggagttgctg
     7441 cagcgggatt tcacctgcat tttatcgatg atacacatac atttggcgga catgtaatgg
     7501 attttgaagt ggctgaagga aaagttgaga ttagccgcat ctcgtccctt gtacagcatt
     7561 ttccagttga tgatccgact tttgttcacg aaacgattga ttatgctgat ttagcagcag
     7621 aaatccaaca agcagaatag aaaaagacag cgagatgcgt tcaaggtgat taacctgacg
     7681 tatctcgttt ttttgaggag aaaacctagc gtttacaaaa aaactgagct ataatcttct
     7741 ccatagatca aaaaggagcg gtttttatca tgtggacaga aaaacagaaa aaagatgcat
     7801 acgaaatttt attattacag caacaaggat tattagaagc agaagataac tggttagcaa
     7861 atttagcaaa ttcatctgca ttgttgaatg agactttgcc tgagactgtc tttgcaggat
     7921 attatttatt cgatggtaat gaattgattt taggaccgtt ccaagggcga gtttcttgca
     7981 cacgtatcaa gatgggaaaa ggagtttgtg gagaatcagc tgaaaaacaa gaaacattga
     8041 tcgttgatga tgtcaaaacc catgcaaatt acatttcctg cgattcagcc gcacaatcag
     8101 aaatcgtagt gccaatggta aaagaaggta atttaatcgg tgttttagat atcgattgcg
     8161 gagtaacgaa agggtatgat gaaatcgatc aagcatttct agaaaaatat gtagatcttt
     8221 tattagcaaa ttttaatata aatgcttttt catttattaa taactaaaat cgtctattga
     8281 aacaaaaaag aagagaaatc aagaataaaa agagccggaa agacagtggg catttctgtt
     8341 tttcggtttt tttatttttt tataaaatca caagtgttat tgattttcat aatcatattt
     8401 taatgttatt atcattttaa ataatgaaaa aacattaagg atggatgaaa tatgaataac
     8461 gaaactatca ttttaggaaa aaaatatatt tgccaaccta ttggcttgaa acaaaaagtg
     8521 attggagaag taatcagtaa attagaaaat tgtgttgtga tctgcgtaga cgaatatcat
     8581 gacgtcgatc gcaatgaaat attagaaaaa tgcggaaaag tagtggcaaa atatactcac
     8641 gtttatgagt tggaaacaac agaatatcta tataactata gcaacaaata tgaacatact
     8701 ttagtttcat aaagatttaa ataaagtgcc ttcaaaagcg agaagaccaa gcttttgaag
     8761 gcactttatt tagttggcag tgattgttca tgatttttga tttattcaaa aggttcgcct
     8821 agagaatctg tctctgtaac gaggcctggt ggagaaactc gataaaaacc tatactgcca
     8881 gaactgtcct attttcggat agacaaacta gtagttttaa aaagatcatc cgatccaatc
     8941 atttcaaaaa atgcaaaact gatatcagga tcatttagct caggcttgtt atcgtaaagc
     9001 atttgtaaag gttgcattta gttaggagta aacgcgaaac tatcatcatt atttgctgaa
     9061 gaagatgaag aagctaattc agagtttgtt tgaaataaag gagacgtgct gacagtttct
     9121 ttaccctgtt ttttgcagag gtagaaactt ttatatcgga agtttctacc ggagaatttt
     9181 tctcatttgt agaaattgtt gaatcgatac tattcgaaat ttgcgtatct gaaggtatgt
     9241 tctttgatgc agaagtccca caagcagtaa gtaacaataa atttgataaa ctgataaaca
     9301 gaattctttt cattatgtac acactcctta tagtatcgtt tagcatacac ctatgctcag
     9361 tattaggcaa aatcaatgca aaactatcaa gtcttttata gtatctatta gtcttagtaa
     9421 tacatatatg gagagggtga tatcccagtt caaaccagat acattggtta ccatctgtat
     9481 taacgattat gcctctaaac gcttttttta tgaaaaaatt tataagtgaa aacgtaggta
     9541 tgatattat
//
LOCUS       DACBYO010000104         9193 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.104, whole genome shotgun sequence.
ACCESSION   DACBYO010000104 DACBYO010000000
VERSION     DACBYO010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.104"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            63..1277
                     /locus_tag="IVD26_002518"
                     /pseudo
     CDS             63..1277
                     /locus_tag="IVD26_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1456..1791)
                     /locus_tag="IVD26_002519"
     CDS             complement(1456..1791)
                     /locus_tag="IVD26_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP6080442.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(1775..2047)
                     /locus_tag="IVD26_002520"
     CDS             complement(1775..2047)
                     /locus_tag="IVD26_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAP6080443.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2498..3301)
                     /locus_tag="IVD26_002521"
     CDS             complement(2498..3301)
                     /locus_tag="IVD26_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAP6080444.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3279..4403)
                     /locus_tag="IVD26_002522"
     CDS             complement(3279..4403)
                     /locus_tag="IVD26_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6080445.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4419..5234)
                     /locus_tag="IVD26_002523"
     CDS             complement(4419..5234)
                     /locus_tag="IVD26_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6080446.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5224..6105)
                     /locus_tag="IVD26_002524"
     CDS             complement(5224..6105)
                     /locus_tag="IVD26_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6080447.1"
                     /translation="MSEMKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAP
                     TKEFVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNL
                     YKPLFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAG
                     ITAWKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVM
                     TIVQGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAV
                     FLGVIFKFVEKGVYYEN"
     gene            complement(6181..7470)
                     /locus_tag="IVD26_002525"
     CDS             complement(6181..7470)
                     /locus_tag="IVD26_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002581297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6080448.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7614..8125)
                     /locus_tag="IVD26_002526"
                     /pseudo
     CDS             complement(7614..8125)
                     /locus_tag="IVD26_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8192..8335)
                     /locus_tag="IVD26_002527"
     CDS             complement(8192..8335)
                     /locus_tag="IVD26_002527"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP6080449.1"
                     /translation="MITAHSGSDNTEENSWAFLRFCLDRQLCFEVDVRQQTDGTLILA
                     HDR"
     gene            complement(8818..>9193)
                     /locus_tag="IVD26_002528"
     CDS             complement(8818..>9193)
                     /locus_tag="IVD26_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6080450.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSLEQLLSTVWLSVRTAFFVG"
BASE COUNT         2830 a         1966 c         1466 g         2931 t
ORIGIN      
        1 caaaatcaat tctaccttag atgttcttat atcactctat cagtcctatt tgacaaagag
       61 ccaagaaaaa gacgttggtc gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa
      121 gttgtggttc tactgtggta gatggaaacg ggaaagcaat tatagtgaaa aatgggaaga
      181 aggaaacgat tgtccgtttt gaacaataca atcatatgcc tttggttacg cgcctaaaaa
      241 agcaacgcta tacctgtaaa aactgtcgta cccattggac ggctcaaagt tattttgtcc
      301 gactcagcca ttcaatcgca gatcatgttc gatataaaat tgcttcttta ctgactgaaa
      361 aagtatcttt gtcttttatt gcgaaaagtt gtcaggtatc tttgactacc gttactcgta
      421 cattgaaaga gtttaaaagc tatttaccaa agccttctaa gaagattctc cccagagtat
      481 tgatggttga tgaatttcgt tcgcacgctt ccatagaaga taaaatgagc tttatttgcg
      541 cagatggtga aacaggaaac ttaattgctg tcttgcctac gcgtaaatta cctcgattaa
      601 caagctattt cttaggctgc accaatccag aagaagtaga attcttagtc acagacatga
      661 acgccgctta cttccagctt accaaacgtg ttctgccaaa tgcgaaagta gtgattgatc
      721 ggtttcatat tgtcaaacac atgaatcagg cactcaatga gttgcgtatc cgtgaaatga
      781 atgagcttcg taaagcagga cagaaaagtc aggcagaaaa actgaaaaag aactggcgct
      841 ttctgctaaa aaatcgtgca agcatcaacc attatgagta caaaacatgg aaaagtttcc
      901 gagcaccaaa atacccattt ctcactgaag caatgatgat tgatcgattg cttgagtttt
      961 ctgcgcctct aaaggaggcg tatccctttt ttcatgaatt agtcgaagcc tttcgagaca
     1021 aagaccctga cttatttttc tccttattgg cagaacttcc cgaaacgtta gatgacggct
     1081 ttcgggagaa gcttcaaaac cttctgacct atgaagaagg tatcaccaac gcaatgatct
     1141 atccttattc caatggaaaa attgaagcga agaataccca cataaagaca atgaaacgag
     1201 tatcctacgg atttaaatca ttcgagaaca tgagaattag aatctttttg atcaatcaat
     1261 taatcaatgt aagataacaa aaaatctgaa ccagaatgtg gttcattctg acccggattt
     1321 gattttgcac aactcatcag tccttattga caaagagcca aaaatctgag ccagaatgag
     1381 gttcattctg acccagattt gattttgtac aacccatcag tccttattga caaagagccc
     1441 ttctttttag tattattata attcttccat gcgttcttcc agtcgctgta aatcgcttgg
     1501 acttaattcc ccaatttttt tccatttgac ctttttgttg tttttgggta attcgtttag
     1561 agttcctacg tcaatccaag attctttttt tagtcctgcc tgtttccaat cccttatttc
     1621 aacgtatttc agctttattt tatcggattt agtatgatat tttgaagtaa ttgacagaaa
     1681 cgaaattgtg tccagtccat tttttagaat atagacaggc cggcgtttac cgccctctgc
     1741 agctgtgaaa gcaacgtaga cggttgctat atcattagta ttcatcttca ttgaaccatt
     1801 cttcaatttt ttcgtcagtg tctagttttt ggacaggcaa tttttccgct aatctttgaa
     1861 tattatggat tcgtttactt ttttccgaca attcaataga aaatgggatt tttccttgct
     1921 caacaatttg cttataaaaa acggtgacgg ctgttttggg gctcatgcct agttcatcaa
     1981 taatgctttc tgcttcattt ttcaattttt cgtccataga aatttgtaac ttagccattt
     2041 tctccacctc tttctgacaa acacattata tcacggaaag agttcaaatg gaattaatac
     2101 aactactttt gaactccttg aaatgcagtg tatttatcta aatataagga aaggatatag
     2161 tgctaaatgg ccttgataga tagaaaagtt tcaaaatccg ccacagcgat aattgaagcg
     2221 aacactcaac gacacacaga acaggaaaag actcctaaaa gaaccaaatt aactaggacg
     2281 tgtctgaaaa ctccacaaag atgtggtatg ctctggtaaa aaacgaatgg cacaaccacg
     2341 aagaccgata tggttcttgg aaaactttct ccaccctttt tgtaattgga gggatagtgg
     2401 tttattgata gcgattttcc aagttcttca agtggaacca gacattgagc accacggcta
     2461 aaaagtgaat gaagtcttta tttttaatca ataattttta atgattacca gtaattggtt
     2521 ttttcatgcg ccctatttct atttgatgtg gagttaaata atgctgataa gtaaaaattt
     2581 ttccgtcaat taaactgcca ctagtgaatc ctgttctatt ggtaaaaaga gaatagtctg
     2641 ggtattcatc tacaccaaat gataaagatt cagccataaa ctgtttttta ccagcaaatt
     2701 cagcactgct accttgatgg atatggccta caaaaatacc taaaatatca ctttcggcaa
     2761 tcaattcagc aaaaccttcc ggaacttcag ttacaataga tggatcttcc cacgacaatg
     2821 gatgatgaac caataaaatc gttccctttt cagcaggtgt acccaaccac tcttgtaatt
     2881 gaatcatctg tcctatcgat atttttcctt cgtgctgggt atcttgagca gaatccaagg
     2941 aaataattcg taacccattt tgattcgtac aatggatata ctctcccgtt tcattgcttt
     3001 caacactcat tccttcaaag aaaacactgc gacgatcatg attcccacga caaaaatagt
     3061 aaggtgtggt tgggaaatat tgatccaaca ttttccgtaa gacttgataa tcagaaatcc
     3121 ccccttcatg tactaaatca cctgttaata gaataaaatc gtacactgtt aacgagagtt
     3181 cttgtaacaa tttttccaat gccaactgtg gatttttaat tgttggaaat agttcagcag
     3241 taaacaagtt agtttgatag ttttctctaa aatggatatc agagagatgc aaaaagcgca
     3301 tggctattcc ctctttcttc aataaaataa tcaggatatc ctaaattttc ttgcgtctga
     3361 taatcaaaaa aatgcattct ttcaggttct atgcggagat tgactgcatc accaatctgc
     3421 caagtaggtt tttcattaag gacaatcatt tctataccat cgactttaac ggtgtacgca
     3481 taactttgac ctaatagctc acgatacttc acttgaccgt gtaaatcgct tgtttctttt
     3541 gaaaaggtta cgtgttctgg tcttatgcct aaatacaatg agccactaac ctgaagaagt
     3601 tgtttttgcc aagctggatt caatgttaaa aattgactgg ctacctttaa tgttccttga
     3661 tcataagtaa ctggcataat attcatgcct ggcgaaccaa taaaatttgc agtaaaagta
     3721 tttttaggtt tcgtataaac atttttcggc gtatcaatca tctgaattct accttcattc
     3781 aataaaacaa tccggtcagc taacgtcatc gcttcaattt gatcatgagt gacgtagaca
     3841 aaagtttgtt tataacgttg atgaattttt accaattctt ttcgtgcatc caatcgtaaa
     3901 cgcacatcca aatttgataa cggttcatct aataaaaaat aattactccg tttaaccacc
     3961 gcacgagcca atgctacacg ctgccgttgc cctcctgaca aatctttagg aagtcgatct
     4021 tggtatggcg ttaaacctaa catcttcaaa gcttcttcca aacggtgctg aatgtcagct
     4081 gtcttaattt tattcgccct taatgcaaaa ataatattct cctttacagt catgtgagga
     4141 tataaagcat aattttgaaa aaccattgcg atctctcgtt ctccacaagg tagcttattt
     4201 gctagttgtg tacctaaaaa aagctctcca ctcgtaattt tttccaaacc agcaatcatt
     4261 ctcagcaaag tagattttcc tgaaccagat ggtcccagta acacaattcg ttctccagcg
     4321 gccacagcta aatcaatttc ttttaaaatg gtatgttctc catatttttt tccgatattt
     4381 cttaattcaa gcgtttctcc catgatttgt cctccaattt atttaatacc tgcagaaaca
     4441 aaagtcccga taatatattt ttgaaaaatt gcatacaaga ctaacggtac aaacattgta
     4501 attaaactaa tcgccattgc tacggtaaaa tttgtcccac cttcagaact aatataggtc
     4561 tgcatcgcca acggcaaagt ataattatct actgtccgta aaattaatac cggccaaaca
     4621 tactcattcc aagaggtaat aaaaaaccaa ataccggtag aagtaatcgc atgtctagta
     4681 agaggaaaaa caattttact catgacggtt gtttgtttga tgttatccaa tgccgccaca
     4741 tctagaaggc tcactggaat ttcccgcatt gtttgcgtca ataaaaaaat gcccatcgca
     4801 tcagcaaatt gtggtattat cacaccccaa gtagtatcaa ttaaattaag ttttgcaatc
     4861 aacaaataat taggaatcat cgcaacagta aaaggaatga acatcgtacc aatgatgata
     4921 aagtaccaga ttttcttccc tttgattcgg caataagtaa aactatatgc cgcaaaaaaa
     4981 gctacgccta acttaacaac cgttataatt gtagcaataa aaaaagtatt tctcgtaatt
     5041 ttgataattg gaagattttc gaacaaatag caaaaatttt ccaaggtaaa cggctgtggt
     5101 atcaaactag taatcgtctg ataggcatct ttcaatggct taaaagaatt ggccataata
     5161 aacaataatg gatagataat aatgattatg atgaacataa ataagagatg tggcaaccag
     5221 cgtttaattt tcatagtaaa cccccttttc cacaaattta aatattaccc ctaagaaaac
     5281 agcaaatatt aataaagtta aaactgaaat tgctgaagat tctccgactt tatacatttc
     5341 aaaagccttt tgataagcat aatagatcac gtttgcacta ccattattcg gtccaccacg
     5401 agtgatgatc ttaatcggag taaacacata ctgcagacct tgaacaatgg tcatcaccaa
     5461 taaatatagt cctgtcgaac tactcatagg caacacaatt gtaaaaaaaa tgcgccagat
     5521 gggtacacga tccaacttag ctgcttcgat catctcttga tcaattccca caattgctgc
     5581 aaaaatgaca atgaaattat aaccaaaaac tttccaagca gtaatacctg caatcacagc
     5641 aattacccaa ccttgtaaat tcatccacat aggcagtctt aaaccaaaat ttcccaacaa
     5701 gacagcaatt ggtcccgata ccggatttaa tatccatgta aaaaccatcc ccgccactac
     5761 caaagaaatc acagctggaa taaaaaataa tggtttatac aaattctgcc ctttttctat
     5821 aactattcct aataaaaagg atgtaatata tgggaacaca cagctcagca agacaaatag
     5881 aacggtatag gacaaagtat tcttcaacac tttatgaaag actggatcag tcagcacctt
     5941 tacatagttg gcaaagccaa caaattcttt agtgggggcc accatattcc agtcaaaaaa
     6001 actcaaatag atcgtataaa tcaatggata aaaaacaaac acgcccaaca aaataattgc
     6061 tggcgccaga tacaaataac ctacatagcg cttcatttcc gacagcctcc tcatccttat
     6121 gtcaaaagca gacgaccttg tttttccttt cttacaggcg ctgtcgtctg cttgctttgc
     6181 ttatttgagt aactcattaa tttccttttg agtagctttc atcgtttcat tgacggaatt
     6241 acctgataaa attttatccc gcatatccaa caatttttgt tcagcttcta atccagcatc
     6301 tccaggaaat gaactccaac tgaccatctt atccatctga tcaattgctg gtatcatcat
     6361 ctgattttca gctaagaaag cttttaatcc attttgggcg tctgcaacat ctttacgtgg
     6421 tggtaaataa ccagtacctt ctgtccattt agctaaagat tcaacactat aaagatattt
     6481 taagaaatcc caagttgctt cctttttctt atccgtttgt gatgtaacag ctaacattgc
     6541 gccaccagca ggtagtttaa cttttttccc ttcccaactt ggtgactcaa ctgctttagc
     6601 agtaaaagta ctattttttt gaatgttgtc cctttgagca atagtggtat agaccatcgc
     6661 gacgttacca tcaataaagc tttgcacacc ttgttcccac gtagtgtgta atgccgtctg
     6721 gtcttttacc atcctttgat ataattcata agcagcgata ccatctttag aagcaaaggt
     6781 agctttgcca tcttttatta cacttgcccc attactttct aaaattgctt gttgtgccca
     6841 attatcagca ggttcttgaa tatacacgcc atactttcca gttttttctt ttattatctt
     6901 agaaaaagtt tgaacttctt cccaagtttt tggaccattt tcatccaagc ccgctgcttt
     6961 taatatatct tgatttaaat ataaaaccgg attactaatg gagtaaggaa tacccacttg
     7021 tttaccatct ttttcagaca gtgccatgat attgtctaaa aaatgatctt taaaataatc
     7081 agcattatcc ggatccactt cttctactaa agattgagga ttagtatatt tgaaattttc
     7141 tgcaaaataa tctttaaaag cccatcccac ttgtactacg tccggtattt ctttggaggc
     7201 aacagaagct tgtaaatttt gcatcaagcc tttatacata tcaggattat attttgctac
     7261 aaccttcact ttgtcttgag attgattgta tttatctact aattcattca ctgtttttcc
     7321 acctagggta tccgcattaa catgccaata ctctatcgtt acacgaccct ccgatttttt
     7381 tgttgtcttg gtattcccac taccacaagc tgccaaagag atgacactta aaacagacac
     7441 aacccctata acaagatttt tctttaacat aacattaact tcctcctaat ttctttatgg
     7501 ccatttttct aatcaagaaa tattatgaac taccaatgta aatttctagt taattttctg
     7561 taaataattc gaaatttgtg catttcgggg tacagggtca ctggacatat ccatcaagct
     7621 aagaataaag cccccatatg gtcatgtatc ccatctccaa atctcttaac tcctctgttt
     7681 tgattataaa atagtttatt ctgtgctcct ttcttccata aataggccca tgcacaacgt
     7741 gaggttatat tataaacacc acagcgcgca aggtactcaa tcgtttctag ttcattgact
     7801 gtccatacag aaaatgtcaa tcctagctgc tgccccactt cacgggccaa cttagttaac
     7861 catccttcat gaatattgac gatttgaacg ctttgatagg ctaatttctg taaggtatcg
     7921 atcaaatctg cttcggtaat atccccaagt tttttccctt cgaactgatt ttcaatatta
     7981 taaaatatat gctttcccca aatcgcagcc caagataatt gtacatagcc actaagaaca
     8041 atttgtggcc agattgatag gtttgtgcca gcgaaaaaac ggccatttcc aatccctctt
     8101 cttttaaatc acagttaatg gtcatggttg ccttctcatt ggccactgct tgaaacacct
     8161 gctcaagggt taccgaatct gggacaactt cttacctgtc atgggctagt attagcgtac
     8221 catctgtttg ctgacgcaca tctacttcaa aacaaagctg gcgatccaaa caaaagcgaa
     8281 gaaatgccca gctattctcc tccgtattgt cactaccaga gtgtgcagtg atcatggtca
     8341 ttttgacccc tcctttaatt ccgtgatttt ctcccacacg tccactatac cgatgaagcg
     8401 ttaatttctt gttaatttct tgtaaattcc ctgcgttttt tcagtaaact agttgtaaat
     8461 cttgcatgct ccttcctacg aactcatgaa tcgtcgattt tgcccttcta gctagtttca
     8521 ccaattaagt agttctacat tccccgcttt taacctacta cacctttttt tgttttcagc
     8581 tattccttct tcttgctgaa agtccttgag gttctttctt acaggatacc atcaaggtgt
     8641 tcaatggctt attcccattg aatgaccgag acttactatc agatttctgc tcgttgaacc
     8701 aagtctttga tacaggattt cttccgtcat cttctcacaa ataccacctt gcgtttctct
     8761 agcgattggt cgatgtgcac cctcccagtg gactgtcact accccttttt gctatgccta
     8821 gcccacaaaa aaagctgtcc tcacagacag ccagactgta gacaaaagct gttccaaact
     8881 cgtaactcga gcttggaaca gctttttatc tacttcgttt cgaatttttg aacaaaaaaa
     8941 taaaggctcc ttgcctttcc atagccaggt ggctaatttc tttaaattca ttgcagcaaa
     9001 cactagcatc gtatgcgtcg cgactttttc caagcctcga tacttggtcc aacgcatccc
     9061 atgcttttct tttgcatccg caaatattcg ttcaatcgtt tgtttccgtt ttttgtaaat
     9121 tgatttattc agatctgtta ggcgaagatg ttccacttca tccatcagat ctccccaaac
     9181 atgtctcgtg atg
//
LOCUS       DACBYO010000105         9114 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.105, whole genome shotgun sequence.
ACCESSION   DACBYO010000105 DACBYO010000000
VERSION     DACBYO010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.105"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(187..1236)
                     /gene="recA"
                     /locus_tag="IVD26_002529"
     CDS             complement(187..1236)
                     /gene="recA"
                     /locus_tag="IVD26_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAP6080451.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(1345..2586)
                     /locus_tag="IVD26_002530"
     CDS             complement(1345..2586)
                     /locus_tag="IVD26_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAP6080452.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(2826..3404)
                     /gene="pgsA"
                     /locus_tag="IVD26_002531"
     CDS             complement(2826..3404)
                     /gene="pgsA"
                     /locus_tag="IVD26_002531"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAP6080453.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(3613..4497)
                     /locus_tag="IVD26_002532"
     CDS             complement(3613..4497)
                     /locus_tag="IVD26_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6080454.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(5274..6560)
                     /locus_tag="IVD26_002533"
     CDS             complement(5274..6560)
                     /locus_tag="IVD26_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP6080455.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(6553..7821)
                     /locus_tag="IVD26_002534"
     CDS             complement(6553..7821)
                     /locus_tag="IVD26_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP6080456.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            8073..8534
                     /gene="mscL"
                     /locus_tag="IVD26_002535"
     CDS             8073..8534
                     /gene="mscL"
                     /locus_tag="IVD26_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAP6080457.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(8593..9039)
                     /locus_tag="IVD26_002536"
     CDS             complement(8593..9039)
                     /locus_tag="IVD26_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6080458.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         2517 a         1967 c         1616 g         3014 t
ORIGIN      
        1 atataggtaa acctttaaat tgagaaactt ttctattaaa ttattctttg tagatgaaca
       61 gatattttta ttttatgtac ccactcgtat aattaaataa ctcacgattt ctttattcaa
      121 taaaaaaacg gcaggtcaag gagagtacct actcttcaga ccagccgttt ttgtttatca
      181 taatttttat tcttctacta aaggcaattc ttcttgtcct ttttcatctt ctgggacagc
      241 gacttcttca ccaataccat aagctgctct aactagagca gaaacttctg ccatcatttc
      301 aggatgatta gccatataga ttttagcgtt ttcccgtcct tgaccaatcc gatcttcttt
      361 ataagaatac caagcaccgc ttttatcaac aatgtctttt tctactgcca tgtctagaag
      421 ttctccttct tgtgagatcc ctaaaccata catgacatct acttcagcga ttttgaaagg
      481 aggtgctact ttgtttttta cgactttgat ctttgtacgg ttaccaacaa tatctgtacc
      541 ttgtttcaat tgttctgcac gacgtacttc caaacggatc gttgcgtaga atttcaatgc
      601 gcgtcctcca ggagtgattt ctggattccc aaacatcacg cctacttttt cacggatttg
      661 gttgatgaaa atagcgattg tttttgtttt gttgatcgaa ccagagagtt tacgcaatgc
      721 ttgagacatc aaacgtgctt gtaacccgac atgtgagtca cccatttcgc cgtcgatttc
      781 tgctcgtgga actaaagcag caactgaatc gactactacg atatctacag ccccacttga
      841 tactaaagca tcagcgatct ctagaccttg ttctcctgtg tcaggctgtg aaagaagtag
      901 ttcatcgata ttcacaccta atttttgtgc atattgcgga tctaacgcat gctcagcatc
      961 aatgaaagcg gccgttccgc catttttttg tacttctgca atagcgtgta gtgcaactgt
     1021 tgttttacct gaactttcag gtccatatac ttcgatgata cgtccacggg ggtaaccgcc
     1081 gacacctaaa gcgacatcta acgcaagaga gccacttgga attgtagaga tttgttggtc
     1141 gattttttcg cccaatttca taatagagcc tttaccatag ctcttttcaa tttttttcag
     1201 tgcagcatct aaggctgctt tacgatcatc tgccaatacg ataatcctcc ttatatttac
     1261 aaatcagagc aacatttcat tatccttatc atatcttttt tagtgaaaaa aagcaagaaa
     1321 aaaccgaaca aatattcgca tttatcattt tcttaaaagc tgttttctca aaagatcaaa
     1381 tccttgcata accgcattat atctgatagc agcacgatct ctggcaaagt gatatttttc
     1441 cgaaaccacg ccgtctttag atgaaatagc gatccatact gttcctgcag attgaccttc
     1501 taacgtgtcc ggtccagcca ctccggtgaa agctacactg taatctgttc ttgctatctc
     1561 acgtgcttga atggccatct gctccacaca ttctttgctg actgttccat attctgctaa
     1621 tagctccgga tcaatctcca gaaaaccagc ttttgtttgg agcgagtagg taacgaatcc
     1681 gcctggaaat acttcagata caccagcaat gtcgcctaat gcggcttgga aggcgccggc
     1741 tgtcaaactt tccgctgctg ttacagtctg cttgttttct ttcagtagtt ccactacgac
     1801 ttttgctagc gaattatcat cgccgtatcc ataaaaatat tcccctactc gttcttggat
     1861 tttttcttct aatgctaaaa gagcttgatt ccctgcctga acatcatttg ttttcactgt
     1921 cagtcgtaat gtcacttcat ttggtttggc atatggtgcg atcgttggat tgatctgtgt
     1981 ctcaatcaga tcttttagct cagtgaccag tcgcgattca ccaatcccat aaaagcgcaa
     2041 aactttagaa attagttttt cttcagaagg aaaacgttcc tctagtaaag gacgtacttg
     2101 ttccacaaac attggtttca actcattagg cggaccggga agaaggatat acgcatgtgt
     2161 atctgtttga taaaaagtcc ctaaagcaag ccctgtacga tttggtagag gaaccccgcc
     2221 ttcgataatc tgggactgtt gcagattgtt tttggtcatt tttcgatggg ttgtttcaaa
     2281 atatgccaat aattttttgt atccttccgt attttgtatg agagacttac cgaggtgagc
     2341 cgcagttgct tcttttgtca ggtcatcttc tgtcggtcct aatccgccac ataagagtat
     2401 gagttcactt cttgtttcag ctagagcaat caactcttct aaacgctgct gattatctcc
     2461 tacaactgtt tgataataaa cttcgatacc tagatcagct agctgttctg acaagaaagt
     2521 ggcattcgta ttcacgactt gtcctagtaa aagttctgtt ccgacagcta ttatttctgc
     2581 tttcattact tcccgctccc ttatatagta tacgctgtat ttttatattt ttttatttaa
     2641 aaagagggca aggagctgtg acaaaaatct tgtcacagct ccttgttcca aataaacagt
     2701 gttctcctgc caaaacctcg gtcataagtc acaatataca taaaacatga aaagctgttt
     2761 tttgaaatta tcccttgtga ctcagagtta gacggcaggc tcacaacctc tccactaaac
     2821 gatacttaca ttgatccttt gaacacaccg ctgtttttga tgaagtaatc cacacctgaa
     2881 tagatagtaa agatcagaca agcataaagc atgatttgat ctactggaat accgatcagg
     2941 ctgaatggga tattattgat aaacagcaag ataatagcaa ccatttgtgt agccgtcttg
     3001 acttttcccg gccaagctgc agccatgact tctccatgtt cgacaagtag taaacgcaag
     3061 cctgtgacgg ctaattcacg acagacaatg atcgctacta cccaaccagg ggcctttcct
     3121 tggtcaacca acatgataaa agcagtcata actagcattt tatctgccaa cgggtccgca
     3181 aacttgccaa aattagtgac aaggcctcgc gcacgggcaa tttttccatc taaccagtct
     3241 gtgatactag ctaaagcaaa aataactgca cctactagct gtgtgacagc cagtgtggtg
     3301 tctcctacgt taaattgtcc ccaatctaaa ggtaaaccta caaccaaaat gaaaatcggg
     3361 atcatacaaa ttctaagtac agttaattta tttggtaaat tcacactatc gactcctttc
     3421 ttccctattc tacgtgacta tcagcgaagt ttccaccgat attatttact tttccaaatg
     3481 aatttattca aaggagtatt tttattgaaa ttgatctttt tgaattaacg aagaaggacc
     3541 gcgacacaga tttgtcacga tccttctttt ttatacctac aagtaaacag atgcgtaaac
     3601 taatttatac gatcattctg cgtattgaag agtaaggttc acattttttg gactctgatt
     3661 gttttcccct ggattaactg gtacggattc tccattcgct ttgatcgttg cattgcttgc
     3721 tgcaccaatc gtgatggtcg catttgttgc tgtttccggt aacacggtac tctgtgtttc
     3781 atttgctgcc agtgtccctt gataaacata ggcattgtct actagcacac ctaaccatac
     3841 acgattgaca gcagtaaatt caagggttac aggcttggta gcgtctgtga tatttactgc
     3901 gatggcactg ccagaatctt ctcctgtagc tattgccatt ttcttttctt cacttgattt
     3961 tgttgttgat tctactgtag aagactcttt ggtctgcgtg ctttgctctg aggaagagga
     4021 ctcctcgact gatccttcta ctttaagcga agaagctgtg tctccgatta ttggatcagc
     4081 ttgacgatct tgccaagtca tatagcccac gacaacgaca atcgccaaag caaccaatcc
     4141 taataaaatg acaggaagac ttgtccaaaa gcgacttgga tgcgattctt cctgatgcat
     4201 tgcttttcta gaagtactta ctgtttcagg ctgcggacgt tcagggaccg atcctgtcaa
     4261 tttgcttttc ccatcaaaaa catcgactaa atggtctcca tcttctccta cagcttcagc
     4321 gtattgccga ataaatgccc gcacgtaaaa tttaccaggc aattggtcaa aatcatcatt
     4381 gtcgattgct tccaaataac gtttttgaat ttttgtaatc tgctgtaatt catctaaaga
     4441 tattttttta ttcaggcgtg cttgccgtaa tttttctccg atggtttcaa aagccactcg
     4501 ttcatcttct ccagtctgtt tgattctccg aagcatctgc tgttgcaacg aaagacgtta
     4561 tgtttgggtg ctgtgacaaa agtcatgtca cagctccttt tttccgaata aacattgttc
     4621 tcctgccaac tcctcggtca caagtcacaa tatccaataa atataagaag ctgttttttg
     4681 aacttgttcc ttgtgactcg gagttaaacg gcaggctcac gacctctttc ttaaacggtg
     4741 ttcaatcagc tgttcctcgg tattagctca aaaaccggca aaatataagg agatattttt
     4801 ccgtatgttt ctctaatact caggtcaaaa cgctgatttc acaacctctt ccttaaacgg
     4861 tgttcaaaag cttgcatctg cggtaataag tccaaccaag ttaaaaacat taagaagctg
     4921 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctcttggtac
     4981 acggtgttcc agaagtagct tcttcggcaa taagccgaaa tatcacaaaa atttgagaag
     5041 caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac aacctctttg
     5101 attacttcgt ttgattttat tttaatataa gttgattaaa agagagcatg atttgtttta
     5161 ttttctcact aatttttcca acacaactaa gaataccata aaagctgatt ttggaggagg
     5221 ttcctactac aagtctaaaa cgaaatttaa gacttttcct cataaatact ggtttatttt
     5281 ggtctcatgt aaaactcgct gaaggcctct tcacttataa atgcttcccc agctgccagt
     5341 acgtctttca tttggatcga atcgatgatt tcaggaagat caaataaagt tcgatcgcca
     5401 aataaacttt gcgtaaattg attggcaata tattcgatcg aatttaatga ttggaaatat
     5461 tgtccaagca ttttcttctt cagcaaatcg agatttgttt ctgacacttc cggatcatca
     5521 gcgaatccaa gaatgatttc tttgactttt tctgctgctt tctctggttc gtccgtatct
     5581 ccgctgaagt ccgcaaagtg aaattcacga tccaagctga attcaaaacc aaagctgtca
     5641 tcgataattc cttgattgta catcgctaga tagtttcgag aagtattgcc taaaatcatt
     5701 tggaacaaca gattgattgc tgttttatag cgtaacagtt ctgttccttc ttgcggcaat
     5761 gtgtctaatc ctttaatacc aagtacaaat ttatctcgtg taatggctgc ttccaatgca
     5821 ctttgtttga tgatttcttt tgtgttttca gggaaataac gtacaatttc ttgctttgga
     5881 gggaaatttt ttgcttcttg gttttcccga ataagtttca tcaatttctc aggctccatc
     5941 ttaccaacta caaataaaac catattgctt ggctgataaa acgtccgata gcacgtatac
     6001 aagtcttgag ctgtgatttt gtcgatactt tcaaccgtgc ccgcaatatc gatatgcaat
     6061 gggtgtgtag gatacaagtt atttagtatg ccaaaaaaca tccgccagtt agggtcgtct
     6121 tcatacattt ggatttcctg accgatgatt cctttttcct tgtttacagt ttcttctgtg
     6181 aagtaaggtg cttgtacaaa atcgatcaga gtcgtcagat tcttttctac ctgatccgtc
     6241 gtagaaaaca gatagctggt tttcgtaaaa cttgtgaaag cattggcgga agctccttgt
     6301 ttcccaaata attgaaagac atcaccatct tctttttcaa acaacttatg ttctaaaaaa
     6361 tgggcaattc catctggaac tttcaccttt tctttttcac catagggaat aaattcgtta
     6421 tcgatcgaac cataattcgt actgaacaaa ccatatgtct tgtgatagtc atttttaggc
     6481 aacaaataca cggtcaaacc gtttggcagt acttcatgat aaagtgtttc attgatttgc
     6541 tcatattctg ttttattcat ttgcatttcc tcctgctaaa aagaagattg cctgcaattc
     6601 gatttgctca gctacttgtt gtatctcttt gatcgttacg ctctccatac gtttcaacca
     6661 ttcttcatca gataattttg tttccggcag ccagctgtcc aaaaaagaag cttcgattgc
     6721 cgcttgcgga gagtctagag aaagcagata ttggtttctc agcattgctt ttgtctgaga
     6781 cagttccaac tctgttattt caccatttcg caaactttct aattgctcgt gaatcagatg
     6841 aagtacttga tttcggttct tttcatcgat accggtttgg acactcatga atcctcggaa
     6901 cgtatccacg ctactagagg cataataagc tagactttct ttctctctga cattcatgaa
     6961 aagtttagag tgaggaaaac cgccaaataa accgttaaag accattagcg caaaacgttc
     7021 tggttcatcg taatacacat ttgtctgata agctaggttc agctttgctt gaacgattgg
     7081 ctcacgtact tgtcgttcct tcacgatatt cacttgaggt tgggtataaa acagatctgg
     7141 ataaactgtt tcccgcgact caaatggtaa ttgcccaact gcttcagctg ctttgtccgg
     7201 atcaacatcg ccgacaacaa aaatgtcgat ttgatcattt gccatcattt cttgatagta
     7261 ggacgctagc gaactagcag tgatcttgtc caaatcttcg actacgccca accctgggat
     7321 cttttgttcc gggctgtttt caaaataaag ttcttgcaag gcataggaag caaaagtttg
     7381 tttatcttcc ttcaaacttt ccaaatatag acgcagattg ttcttttcca agtcaaacgt
     7441 caactgatca aactgatgat ttttaatatt tggataaaat aaaacctctt ttaaaaaatc
     7501 taccgcttga gaaaaaaggt ttggatcatt gacatattca ccattcacaa aactgatccc
     7561 tgcgtttagc caatgtaaat ttcctttttt tctaactgat aatccaaagc ttgcgccata
     7621 aagctctgca agttgcgcac ttaactttgt ctgatccgga taattcaaac tatttgtttc
     7681 caacatgctg ctgagaagtg aacgtttcgt gatgacttct tgttgcagac gcgcagtaaa
     7741 acggataaaa atccggatcg ttttgtattg ttttgttggt aagacatgaa gattcacgcc
     7801 ttctgccaat tgatacacca tatttatatg ctccttttca cagttgattg cccgcttact
     7861 cttttaatgg gtcaacctgc cttttttact tattcctctg cttgaaattt ataagttcag
     7921 gcaattcgcc gttttttcta aatgatgtta cactttatag tatagcatag atgtttttta
     7981 tcaaaagaaa cagacggcta aaagcgtata ttgttttttt attttttatt tttcgatata
     8041 ctaaagacaa ataaaagaag ggagggtcat tcatgatcaa agaattcaaa gagttcatca
     8101 tgcgtggaga tgtcttggat cttgctgtcg gcgttgttat tggtagtgcg tttacaagca
     8161 tcgtaaacca agtggtgcaa ggcttgatca caccactaat aggttggttt gtcgcaatga
     8221 tcacaggtac ttctgattta gaaggagcac tttcaattct tgactggtcg ccgacaaaag
     8281 gcgtcacatt tgcgtttggt aacgttatta gtgctatcat tacatttctg atcactggtt
     8341 ttgtcttatt cttagttgtc aaagcggcaa accgtgcgaa gaatttacgc tccaaagaag
     8401 agcaagtgga agtggaagaa actcctactg cagaagatta tcttagtgac atacgcgatc
     8461 ttcttgccaa acaagtggca gaagacaata cacatccagt agagcaaaca aatctttccg
     8521 atacttctaa ataataaaga atctaaaaaa aagaaagccg attttcagtg tcggctttct
     8581 ttttttagat tcttaacttg ctacttgttc ctttttcatg tcgatatgtg gaatatcatc
     8641 ttccaaatac acatctgaga ttgccttgaa tccaaacgac tcataaaaag cttgtaggta
     8701 ttcttgtgcg ccgatcacga ttggtttttc tggaaaattt ttctggatca tgttaatcgt
     8761 ttcttgaaca atctttcttc ctaaaccatc tttacggttg tcctgatgaa caaggacacg
     8821 tccaaaatgg atactctccg cttcttcata tactcgcgtg taggcaagga tcttcccatc
     8881 agtatcttga aaaaacgtat gccaagcttg tccatcaatg tcatcaactt cttgataagg
     8941 acactgttgt tccacaacaa aaactgcgat tcgttctttg acgatcgcgt aaaactctgc
     9001 tgttgacaat tcttcaaatt tctttacctg atattccact aagcaaacgc cccctgcttt
     9061 tttattctta gcataccgat tcgcacacaa aaaagcaaac gaaccttacg aatc
//
LOCUS       DACBYO010000106         9040 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.106, whole genome shotgun sequence.
ACCESSION   DACBYO010000106 DACBYO010000000
VERSION     DACBYO010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9040
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.106"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(200..868)
                     /locus_tag="IVD26_002537"
     CDS             complement(200..868)
                     /locus_tag="IVD26_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP6080459.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            1002..1289
                     /locus_tag="IVD26_002538"
     CDS             1002..1289
                     /locus_tag="IVD26_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080460.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1705..3243
                     /locus_tag="IVD26_002539"
     CDS             1705..3243
                     /locus_tag="IVD26_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAP6080461.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3240..4205
                     /locus_tag="IVD26_002540"
     CDS             3240..4205
                     /locus_tag="IVD26_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6080462.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4192..5514
                     /locus_tag="IVD26_002541"
     CDS             4192..5514
                     /locus_tag="IVD26_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP6080463.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5577..5681
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5755..6498
                     /locus_tag="IVD26_002542"
     CDS             5755..6498
                     /locus_tag="IVD26_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6080464.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6513..7505
                     /locus_tag="IVD26_002543"
     CDS             6513..7505
                     /locus_tag="IVD26_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP6080465.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7517..8254
                     /locus_tag="IVD26_002544"
     CDS             7517..8254
                     /locus_tag="IVD26_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6080466.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8244..8966
                     /locus_tag="IVD26_002545"
     CDS             8244..8966
                     /locus_tag="IVD26_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAP6080467.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
BASE COUNT         3024 a         1533 c         1880 g         2603 t
ORIGIN      
        1 cctcaaattt ttttgagttt aagcgaattt tttctcccaa taagtaagaa aataatggca
       61 aaataaaaaa acaaactatt ttcgcagatc gtttgcaaaa atagtttatt tttttataaa
      121 gaagatttta ctgaataata tcattttagt ttacataatg atatttctgt aaattaaata
      181 aagtagtgaa aaataagaat cagtgctcta actgttcaag aggatcaagt ggttcaaatg
      241 tttctgtagt ctgttttgct tccaattggg gcaaaacaga tccaatttcc agatacttca
      301 ctttattcaa tgtataagat agaatagaac agctaagtaa tgtatacaga aaatgtgtga
      361 gatccaaata aagcaaggag acaactaaaa taccaaaagt aatcaagaaa agacttttgc
      421 caatcttaat atgaaaatat ttttcaatgg cttgataaat gatatctgtt ccgcctgtgc
      481 ttccgccgaa tcgaaagacg agaccgcaac caatgccaga aagaatacct gtcatcaaac
      541 tattgatcag tagactatct acagcaaaat gtatatgaag gctctcccat aaatgtaaaa
      601 agaaaactag cgcaaatgtt ccgacgatcg tccggagaaa agcgtgtttt ccaaaaagaa
      661 acaatgagat aagcaataaa ggtaaattaa aaagcagtga agtgacagaa ggagcgaatc
      721 caaaaagatt atgcaaaagc aaagcaatac cagtaacccc accatctgcc agcttagatg
      781 gaatattgat tcctgtcaca gctaatccgt agattcctgc gcctaaaatg attccgcaca
      841 attctgtaaa taaatttaat tttttcattt ctagcctctt ttcttttgaa aattttcagc
      901 aacttcttta ttatactgac ttatactctt acttcaagag gaaaatgaaa aaaaattatt
      961 tttggctgtt tctttttatt tatcaaataa ggagtggaaa aatgcgagca gcagacttat
     1021 tgacaattct tacaaaatca cccaaaaaaa cagagtatca aggagttttt ttggctcaag
     1081 aacaaaaact ggtgcctgtg acaatggtcc agataaataa agcaaatcaa tttatctttt
     1141 tatttgaaca cggcaaagca ccacttgcta tgaaagacat ctttcttttt ttgatgaaga
     1201 accgtgagaa agctgtttat tatcagtcaa aagaagaact cattcctctt tatggagtga
     1261 aagagataga aaataaagtg gtgatataag taaaaataag aaaacaagac gtttatgatg
     1321 tcaaaacaac cattttttac atttttggca aaaaagtgtc atgatacagt ataatattcg
     1381 ttgaacaggc caataaaggt gttctccccc acgagatttc tactttattg gctgtttctt
     1441 tttattaaaa taaaagttgt gtgtgtaaaa aagatatagc tgattccaag tgacaatttc
     1501 gtatagattt ttatggtatt cgtagtgaaa aaacgagaac caaaaagttg atccgacttt
     1561 gttgcttgga ttcttttttt gtcagcatat ttagaggtat ttttttcttt tttttgttcg
     1621 tgctgtaagg ttaaggcaag acaagttagt tgggaaaaag gaaagaaatg tttatactta
     1681 aagaataaca gaaaggaagg tcgcatgaat aattttatac aaacattaag tgaaagaaaa
     1741 ggcgagttgc tggaagctgc atttcaacat ctgtccattt ctctcatttc tttgctgatt
     1801 gcagcactga ttgctattcc tttagcgatt tgggcagcca atcataaaaa aatggcagaa
     1861 gtcttattgc agatcacggg tgtgctccaa acgattcctt cacttgcctt attaggttta
     1921 cttatcccat ttgtagggat cggaactgtt ccagcattga ttgcacttgt tatttacgct
     1981 ttgcttccga ttttccaaaa cacgtatatt ggtctagctg aaattgaccc gtctattgaa
     2041 gaagcagcgg tagcatttgg tatgtccaga atgagacgct tgctgaaagt agagcttccc
     2101 atcgcattac ctgtcattat ctcaggtatc cgaactgcct tagttttaat catcggtacg
     2161 gctactttgg cagcattgat cggagcaggt ggattaggga catttatttt gttaggtatt
     2221 gaccgaaata cacctgtttt gacattgatt ggtgcgatca gttctgcctt gcttgcaatt
     2281 atattcagcg gactgattcg ctggttgcag cataagaaac ctcgatattc catcattact
     2341 ttagcagcag tggtgtgttt atttggcggc gtttctttat atcagtctgc cttgtttaaa
     2401 aatgaaacca tcacgattgc tggaaaatta ggagcggaac ctgaaatcct gatccaaatg
     2461 tataaagaat tgattgaaga caacacaaaa acagaagttg aattaaaacc gaattttggc
     2521 aagacgagtt ttttgttcaa tgcactggat caaggtcaaa tcgatatcta tcctgagttc
     2581 acaggtactg tcctagaaag cttggtgaag gtacctgaag caatgaaaag tgctgatttg
     2641 acaaaagaaa aaacatatga cgaagcagaa gaattattga ataagcaatt cgatatgaca
     2701 ttattaaaac caatggctta ccaaaatacg tatgccttgg cagtcaagag atcttttgcg
     2761 aacgaacatc aacttaaaaa gatttccgat ttggcagcta tctctgatca gatcaaagcg
     2821 ggattcacac tggaatttat tgatcgttca gatggatata aaggaatcca agaagcatat
     2881 ggcttgaatt tttcaagtgt acaaagcatg gagccaagtt tgcgttacca agcaatcaat
     2941 aatggagatg tcaatattgt ggatgcctat tccacagata gccagctcaa ggagtacgat
     3001 ctagtgactc tagaagatga tcgagggtta ttcccagctt atcaaggcgc accgctgatg
     3061 aaaaaagatt ttgctaaaga acatcctgaa atcgttaaag cactgaataa attaagcgga
     3121 aaaataacag aggatcaaat gattgatatg aattaccaag tcaatgtcga aaagaaaaag
     3181 ccgacagaag tagcacgaat cttcctgaaa aatgaaggat tagtaaagga ggaagatcag
     3241 tgactaaatt aatcgagttc aaacatgtgc aaaaaaagta tgatggaaag tatgtcatcg
     3301 atgacctaaa tctggcaatc aaaaaaggag aaatctttgt tttggttggt ccttccggta
     3361 gtggaaaaac aactactttg aaaatgatca atggattatc taaaccatca gcaggagaca
     3421 tctacttcaa aggaaaatcg ttaaatgaat ataatctgca gaaaatgcgg tggaatatgg
     3481 gatatgtgct gcagcaaatc gctttgttcc cgaccatgac agtcaagcaa aatattgaag
     3541 tcatccctga aatgttaggt tgggaaaagc agaaaagagc agaccgtgta gatgaacttc
     3601 ttcaaaaagt tggcttatct cctgatattt atcgagatcg tatgcctaga gagttgtctg
     3661 gaggagaaca gcaacggatc gggatcatcc gagctattgc tgcaagccca gatgtgattt
     3721 tgatggacga gccatttagc gcattagatc cgatttcaag aaactcatta caagaattgg
     3781 ttttgtcctt acacgaagaa ttgggcacga ccatcgtttt cgttacgcac aatatggaag
     3841 aagcaatcaa gctaggtgat cgtattgcat ttatgaagga tggagaaatt atccaatgtg
     3901 acacaccaga gcagttattg atgaatccta aaaacgacta cgttcggcat ttctttgatg
     3961 aaccgaaaca gacgaaagag tggcgagtag aagatttagt cgtcaatgga tatttcttaa
     4021 atgaaatacc agaaaatgct cgtcaacaag tttgctttga tacgcctatg aaagaagtat
     4081 attcgcttct ttcggtgtat ccaagcattg tgatagtaga aaagcaaaga agtattgggt
     4141 cgctgacaag taaagaaatc tttgcttttt taagtcgaga ggaggaagga aatgaaaaca
     4201 tatgatgcaa tcatcatcgg ttcaggtgtg agcggcttaa gtgctgctta tggattgaaa
     4261 gaagcaggta aaacagtact agtggtcgaa gaagatctat ggggcgggac ttgtcctaac
     4321 cgtggatgtg atcctaaaaa agtcttgtta agtgcagtag aggcacgtaa tcgggtaaaa
     4381 caattgagtg gaaaaggttt taacgagatc ccaactgcca actgggaaga acttcaaaaa
     4441 ttcaaacgaa catttacgga tccagtccca gaaagccgaa aaaaacaatt agcagaagct
     4501 gaaatcgatc atctttcagg aaccgctcgt tttttggatg attcatctat tgaagtcaac
     4561 gaagaagtct tccatgcgga ttacttagtt ttggcaaccg ggcaaagacc tacgatctta
     4621 ccagtggagg gaaaggaata cttgaaaact agtgcagact ttttatcatt gcctgtactg
     4681 cctaaagaaa tcatttttat cggtggtggt tatattgctt ttgagctagc tacgattgcc
     4741 aatgctgcag ggagcaaagt aaccattgtc catcataatc aacggccatt aaaagaattt
     4801 gaggcgtctt tggtagagga agccgtccat caaatggaag catctggcat tcagtttgct
     4861 tttggtgttg aaacccaaaa gatcatttca gaaggtactc gctatcgttt agtcggaaaa
     4921 gagacggaat tagtagcaga tatgattttt tgtgcgactg ggagacagcc gaatacagaa
     4981 tctttagcac ttgagcaagc gaatatcgtc tttgataaac acggaattgc agtcaatgat
     5041 tatctgcaaa cgagcaatcc aaaaattttt gcgtgtggag atattgtttc aaggaaaacc
     5101 ccaaaattga caccagtcgc cacttttgaa ggaaattatg tagctaagcg gataacggat
     5161 gcaacaagcg aacctatcaa atatccgatt atacctacga tcgtctacgc cagtcctaaa
     5221 cttgctgaag taggagttac aaaaagtcac gcctcttcgt cagatcaagt ggtagagatg
     5281 gatcttacca gttggttcac ctatcatcgt gtcaatgaac cagttgctaa ggctgaattg
     5341 acctttgacc agcaaaatta tttgattggt gctgcagtga ttagcgagca agcagacgaa
     5401 ttgatcgatg atttgacact cgtcatcaat caaaaattga ctaaaaaaga gttggatagc
     5461 tatatcatgg ggtatccgac attggcaagt gatctctcct atttattgaa ataatcagca
     5521 tgataactaa agcgcttgtt gctttttcct tcttgtgcta cactttaaaa aatgaatacc
     5581 tgtttctggg gatgtcgtag acgacatgag agtaagttgt gaacttagac ccattgaacc
     5641 tgtcagttaa tactggtgaa gggagaaaca tagcagacgc ttgaagcggg ttactatgtc
     5701 gtgcccattt caagcgtttt ttgttattca tattagaaga aaggaggtaa caaaatgaag
     5761 aaaaatcttt atccagcagt cagtatggca ttcattttaa ttatttggca gattgttgtc
     5821 atagtttgga aaatacctgc ctttatttta cccggacctg ctgctgtatt ttctgcatta
     5881 gcggcagatg cacaagtatt actttcccat tctgtcacga cattaaatga agcagtgctt
     5941 ggtttggtaa tagctagcgt tctttctttt attactgcct tggcaatgga ttattggaag
     6001 tttttagaaa tgtcttttta tccgttacta gtgatttcac aaatgttgcc aatcatggtg
     6061 ttagggccat tacttaccct atggtttggt ttcggtatgc ttccaaaagt gatccttgtt
     6121 gtcttgataa gctattttcc gatcgtagtt tctttttcgg atacattgag gaaagtatca
     6181 aaagagcaaa tcatcttttt gaaaacgatg ggggcagata cagggaagat ttatcgaata
     6241 tataaaatac cagcgggttt atccggcttc ttttccggtt taaaagtggc tgctacttat
     6301 tgtgtcagcg gagcagtcgt tggagaatgg ctaagcgctc aagcaggctt agggtattac
     6361 atgatacgcg taaaaaacag ctaccagatc gataaagttt ttgctgcgat catttgtgtc
     6421 attctattga gtttattgct gaatggcgct tgttcattat tgaaaaaagg gtattatcgt
     6481 atgctttata ttttttaaga gaaggggatc aaatgaaaaa attatggctt ttattaccgc
     6541 tactgttgct tttatccgct tgtggcactg caaaagaaac aagtagcaaa caagaaataa
     6601 aggatttgaa aaaagtgaca cttgttttgg attatgtacc gaatactaat catactggca
     6661 tctacctagc aaaagaaaaa ggctattata aagaggctgg tttaaatgtc caaatcatcg
     6721 aaccaggaga taattcgaca agtattggtc tagtaggtgc ggacaaagca caatttggtg
     6781 taagttatca agaagatgtc acttatgctc acgcagatgg acagaatata ccagtcaaag
     6841 caattgctac agtgatcaaa cataatactt ctggattcgc caccctatca gacagtaaca
     6901 tccattcacc aaaagatttt gaaggaaaaa catatgcagg ttggcaaagt ccaagtgaag
     6961 aagctgtctt aaaagctgtg atggaaaaag acggcgggga cttttcaaaa ctgacaatgg
     7021 taggaagcaa tggagaaggg ccagaaagct taggaaaatc ctcagatatc caatggtact
     7081 ttgaaggttg ggatatgatc aaagcaaaag aagcgggtat tgaactaaac tatatcccat
     7141 tgaaagaatt agatgaacgg ttagattact atactccggt aattattacg aatgatcaac
     7201 tgatcaaaag tgatccagaa ttggtacagt cttttatgga tgccacgaaa aaaggctatc
     7261 aggaagctat taaggatcca aatgacagtg ctaaactgtt gcaaaaatat gcaaaagaaa
     7321 atgatcggac gtttttagaa gaatcacaag cattcttgtc aaaaaattat acggatgatc
     7381 ctgagaattg gggattgatg gaagaaaaag tttggcgcaa ttatacagct tttatgcagg
     7441 aaaacggatt gatcaagcaa gatgtacctt cgcaagaact attcactaat cagtttataa
     7501 aataggagtg atagatatgt caatccaaat cagccacttg aatgtagtca ttgaaaacct
     7561 gaaaatatta gaagacatcc atttcactat ccctaaagat acctttacat cgattgtcgc
     7621 gccaagcgga gccggtaagt caacattgct gaaaacttta acaggagtcc agcctatgac
     7681 ttctggaacg atcaaagtag acgatcaaaa agtaactggt ctccatacag catttagtta
     7741 tatgccgcaa gaagatatgt tacttccttg gctgagcgtc tatcaaaacg ttacgttata
     7801 tcaaaaaatc aatcatctaa caatcaatga agaacaagta agggattatc tggatatctt
     7861 tgggttaaac ggctatgaac attttttgcc ggaacaatta tctggcggga tgaagcagcg
     7921 aacggccttg ttacgaacaa tcatgaatcc ttcttcttac ttgcttcttg atgaaccatt
     7981 tggagcgtta gatgctatga ccagagggca gatgcaagac tggatgttga agctgcctaa
     8041 aaaagcaaag cggactactt tacttgtgac gcatgatatc gaagaagcaa tttatttatc
     8101 agacaggatt cttgtgcttt ccgcccgtcc ggcacatgtg attgctgaga ttcaagtgcc
     8161 tgaaaaacga cggtcacgtg aatggctact gcagcaatca gagttgaagc aaacgattta
     8221 tcagttattg gcaggtgaat tagatgttaa gtgatgctca ttgtcattta gatgggagtc
     8281 agagtttagc actccttcag caggaacaca cgattttgac gatcatcaat tgtgattcgc
     8341 cagaagaatg gaaggaaaac agacagcttg cagcaagtaa gactcaagcc ttaagttacg
     8401 gtatccatcc ttggaaagca gatagctata cgtttgaaca agttgagcct tttttgaaaa
     8461 aagcaaggat catcggtgaa atagggttag ataatatttg gacgaatgta ccgatgacta
     8521 cacaaaaaaa agtatttgag cgacagcttg cttttgcagc cataaatgag aaacctgttg
     8581 tactgcacac aaaaggatgc gaaaaagaga tcttaaatta tatccaagct taccctaatc
     8641 actatttgat ccattggtat tcttctttgg actatcaaca agactatatt gatttaggct
     8701 gttatttcag cattggtctt gatttgaaaa agaatccagc agtctggcaa ctagctaaag
     8761 cagtcccaat cgaccactta cttattgaaa cggatggact acatgcagca gagtgggctt
     8821 taggggggat tttttcagaa aaagattatg tctcactgct tgaagaacag ttaaagacaa
     8881 tcgctgagat caaagagcta tcagttgaag aagttaaaaa aaatacttat caaaacttgg
     8941 aacgtttcat tagattaggt aaataaaaaa gagatgtgac acaactagtg tcgcacctct
     9001 ttttggcttt ctttgtataa aagtaaactg tttgattaat
//
LOCUS       DACBYO010000107         8942 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.107, whole genome shotgun sequence.
ACCESSION   DACBYO010000107 DACBYO010000000
VERSION     DACBYO010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.107"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            51..260
                     /locus_tag="IVD26_002546"
     CDS             51..260
                     /locus_tag="IVD26_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080468.1"
                     /translation="MICYISFLILGLPQAVFPEMFSGDWGIVSYSILTLIAMVLGTSF
                     YNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            467..667
                     /locus_tag="IVD26_002547"
                     /pseudo
     CDS             467..667
                     /locus_tag="IVD26_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1154..1333
                     /locus_tag="IVD26_002548"
                     /pseudo
     CDS             1154..1333
                     /locus_tag="IVD26_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340501.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1379..1984)
                     /locus_tag="IVD26_002549"
     CDS             complement(1379..1984)
                     /locus_tag="IVD26_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6080469.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2166..2501
                     /locus_tag="IVD26_002550"
                     /pseudo
     CDS             2166..2501
                     /locus_tag="IVD26_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2666..2893
                     /locus_tag="IVD26_002551"
                     /pseudo
     CDS             2666..2893
                     /locus_tag="IVD26_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3019..3990
                     /locus_tag="IVD26_002552"
     CDS             3019..3990
                     /locus_tag="IVD26_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6080470.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4130..5443
                     /locus_tag="IVD26_002553"
     CDS             4130..5443
                     /locus_tag="IVD26_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP6080471.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5486..6352
                     /locus_tag="IVD26_002554"
     CDS             5486..6352
                     /locus_tag="IVD26_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6080472.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6349..7197
                     /locus_tag="IVD26_002555"
     CDS             6349..7197
                     /locus_tag="IVD26_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006639650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP6080473.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7211..8683
                     /locus_tag="IVD26_002556"
     CDS             7211..8683
                     /locus_tag="IVD26_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAP6080474.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            8700..>8942
                     /locus_tag="IVD26_002557"
     CDS             8700..>8942
                     /locus_tag="IVD26_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6080475.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPK"
BASE COUNT         2830 a         1515 c         1831 g         2766 t
ORIGIN      
        1 atttaaaaag aaaagtgaca gataggaata aaaacttatt aaatgtagtt atgatctgtt
       61 atatttcatt tctaatacta ggtcttccac aagcagtgtt tcctgaaatg ttttctggag
      121 actggggtat tgtcagctat tctatattaa cattgattgc tatggtttta ggtacttcat
      181 tttataatgc ttttgtaagt aagcatgttg aggaatatga agtattaatg tacttaaaag
      241 agaaaaaaac aagtaattaa tatgagaaca ccacgcatag tttttatttt gagatattct
      301 agaatgaaac acattaagaa cgaaagcaaa gcaaaagacg ccagaacttc tactaccttc
      361 taagtttttt catatttgtt tgttatgcta tacatagatc tgcataatta gacttgcgct
      421 gcccgttatt gaagtttcag gcagcgctct ttttggggga tcgataatgg aagaagaaaa
      481 aatatttgag aaacgctggc agctagcatc aagtgaacaa agagcaagat acaataattt
      541 gatcacctcc taccccactg ttgactagac atataaggaa aagaaatact tactttggct
      601 gtgccagtta gatatagata cctttgaaac atttgaagtg atcctagata aaattaaaca
      661 gaattgatca gaaacaagcg aagccttctc tcggttcgct tgttttgcta tttattagtt
      721 ggctcagggc aactctaagc tcgtttgaaa gaaaaccgat ggataatccc cttgtttgta
      781 ccactttaga atacatggat gtacgtattg ccattgactc ctattagtta ctgaaaaaaa
      841 atttaaacaa gttgagtatt gcagataaat agctccagtg aggtgaataa ctgctccact
      901 caaggcaata gatagctcca tccagggcaa caaactgctc cactttcata tttaatagat
      961 gaataacctt ctgtataata gaaaggcata cctttcggta tgacaactta tacagaatgt
     1021 tattttattg gttcactatc gaaaaatttt ggagctttat ttttccggta tttctcaacg
     1081 aacgattagt ttaactgtgg gaagctccag acatacgatt cgagaagtta cttctcgagc
     1141 agacaggaag ggggtgactg aactaaccgc tgatatgagc gatacttggc tgtaggaata
     1201 tctttttccg gaaaaacaaa caacagcacg aggttacctt cctgtagact gggaatatgt
     1261 tcataaagaa ctaatgaaaa agaatatgac attgaaactc cttcatagag aatatggggt
     1321 acatggaaca tagaaacgaa aatgcacggt agaaaagcga atgaatatag tataaattct
     1381 acaaatcatt cgctttcttt attttatata tggttggtcg agagagacca ttttctttgg
     1441 caatttctgc aactggaact ccttgattta acatgtccac cacagtttta aagactaatc
     1501 gtttttgcgg atctgttgag ttctcagaat attcaattgg tcgcccctta tatcgaccag
     1561 cttttttggc caataatact ccttgccgct gacgttcacg gattttctca cgttcgtttt
     1621 gtgcaatata acttagcaat gataaaaaca tatcgaacat agcagtatct aggagttcat
     1681 ttccagtatt aaaatctaaa aactgtgcat ctagtatttt taatgctact tttttctgtt
     1741 tcataaaggt aactgtattt tttatgtctt cataatctct gcctaggcga tccagtgatg
     1801 caacaatgac acaatcacct tctcggatat aatttagtaa tttttgaaac tcaggtcgct
     1861 ggatatcttt accactggct ttttcttgga ataatttatc aatgttaagg tcttccatca
     1921 ttgccaattg tcgatctaaa ttttgatctt gtgaagacac tctaatatat ccaatttttg
     1981 ccataaaaac tccttttaaa aaatgatata atttacatgt aaaatttact tgtagtttta
     2041 ctgttatcat agcattttta aaaataaatt ttaagtctac ttataattta ctttggaggt
     2101 tttgaatgaa tgaaattaag cgcaataaaa attcttttgg tgtttattta ggagagccta
     2161 gctcggaaca gttaaataaa ggtgaagctc gtcatgctct atgtcgaaat atattttatg
     2221 gtagaaaagg caaactttat caaacttatt acgacggtat ggaggaacag ctcaacgcat
     2281 taggattagt aactaatgct atcatatatt ggaattcact atatttagaa aaagtctttg
     2341 aacaaattaa aacggaaggg ttcgactgtt ccgaagaagt gttacgcaag caatttccat
     2401 taattagtga tcacattaat tttgttggca aatatagttt ccgctatgaa aaagaattat
     2461 cgaatggaat actacgtccg ttaaatatag agaattattg agaatgttcg tcttttggtt
     2521 cctaccgtgc attttcgcac ggatgttcca gatactattt ttgaatgtat aaaattgaaa
     2581 acacaagaat actaataaat caacgattct tgtgttttta atttttcact accgtgcatt
     2641 ttcgtttcta tgttccatgt accccaatct tgaaaaatta attaaagact tagataaagc
     2701 cattgacgac ttagtcgtgg tgctaccgga gtatcaatgt ttaaccagta tcccaggtat
     2761 tggtcctgtt taggctgctg gaatactcgc tgaaattggt ccaattgaac gtttttctga
     2821 tgaaataaaa ttgacaaagt atgccggcct atattggcga cagagtcaat ccggtaaatc
     2881 tgaatacgaa aattttttta cgaaaagctt cacgtctaat atctatttta aaataaaaat
     2941 attcctgcta atttggaatc gtttccttct tttggtataa taatacctga aattcttttg
     3001 agaggagttg ttcgtgaagt gaaaactact atgaaggatg ttgctgcgtt agcaggagtt
     3061 ggtgtgggta cggtatctag agtaataaat ggagtaaagg tgaaagaggt taccaaagaa
     3121 aaagtaatgg ctgcaattag tgagcttaat tatgagcctg atgaatatgc cagaggtatg
     3181 aaaacgaata gtagcaatac aatagctctt attttaccta cgatttggca tcccttcttt
     3241 tccgagtttg cctactatgt agaggaagct ctcagccaaa aaaattataa gctttttttg
     3301 tgtaatgcga acggcagtgc ggaaaaagaa aaagaatata tccaaatggt caagcagagt
     3361 aaagtagacg gaattatagg tattacctat tcagacattg ataaatatgt atcatcaaat
     3421 ttaccatttg tcagtataga ccgccatttt tcggaacagg tttcttatgt aacggcagat
     3481 aattatttag gtgggcaaat tgccgctcaa gaactactta ctcgtaactg taaaaacttg
     3541 tgctatgttg ggggtgtttc accttaccct aacgaaacaa acaatcgtaa agctggtttt
     3601 tacaatattt gtgaggaaaa taaaatagct gtgaaggtat tggatatgcc tgaaccaatt
     3661 agcaatttag aggaacaatt gctcgctttt ttttcggata atcctgaaat tgatagcatt
     3721 tttaccatca atgatttcat ggctttggat gtgataaaag cccaaaaaaa actagggaag
     3781 gaagcaccta aggattttca aattattggt tttgatggag tcaagctatc gttgcaaaaa
     3841 gactatttac tatcaacgat tgtacagccg atagaggaaa tggccaaggt ttcagtagaa
     3901 acactcatgg cgatgatttt aaatgaagaa ccgcctaagc gtgtggtagt accggttttc
     3961 tttcacgctg gagagacgac taaagagtaa aaaaccggtt tataacgatt tttttgagat
     4021 aggttgacag aaagtgattt caatgatatc ttaaaaccaa ttaattggaa acgttaccaa
     4081 ttaattgaaa aataaaacgg aaacgtttca aaaaatagga ggaacatcga tgaaaaagag
     4141 aatgttagca attgcagcaa ttttagcatt aacagctgga ggacttgcag gatgtggcag
     4201 taaggagaaa agttcaggta gcagtgatcc aggagaaatt aagatttggg ttcagttttc
     4261 tgatgaaacg cctgaaggaa aagcttgggc agagattgtg aacaatttta atgatgaata
     4321 cgagggtgaa tataaagctg ttactgagta tattcctcgt agcggaagcg gcggtggata
     4381 tgaggataaa gtaaatgctg caattacaac caataccctt cctgatgtta ttacgttaga
     4441 tggaccgaat actgcagctt atgctcattc aggagtcatt gctccattag atgattattt
     4501 gaaagatgcg gacatggatg atgtattaga cagcattatt cagcaaggaa cctacgatgg
     4561 caaaatgtat gcgtttggtt tctcagagtc cagtgtgggt gtctattaca ataagtcgct
     4621 gttcaaagat gctggaatta cagaagatca attgccgacg ttagaagatc cttggacttg
     4681 gacggaattt caagcaattt gccaaaagct gactgataaa tacaaaacgc ctgcaattga
     4741 tatgcaaatg gcgtcgggag acgaaatgct gacctacgca tatacaccat ttatatggtc
     4801 gaatggcggc gatgtcgtta atgctgatgg aaccaaagcc gaagactatt ttaacggtaa
     4861 aaaatccgtt gaagcgttgg aatttattca agaattggtt gaaaaaggtt acaccacaat
     4921 cagtcctatt gaaaaaggat ttgaaactgg caaatatgcc atgatgctga gcggttcttg
     4981 gacaatggca gatttagagg aaaactatca agagattgat tatggtattt tgccttaccc
     5041 cgtttcagat gcaactgggg agttagtttc accaaccgga agctggcagt tagcaatgac
     5101 tgagaaaaca gagaaaaagg atgcttctgc ggcctttatt aagtttgcaa ccagtacaga
     5161 atctagtcgt attatgagtt tagggaacag tgttctacct atcagaaatt caacagttga
     5221 tttaattaaa gatgaagtgt cggaaggaat gcaggtatta attaagcaaa accaactttc
     5281 tggacatgcc cgcccagtgg ttgtagctta tccgcaagta tctagagcat tccaacaagc
     5341 agttcaagat attagctact tcgaggaaaa cccagatgta caaaaagtag cagatagtcg
     5401 cgctgctgaa atgcaacagg caattgatac ttcactaaaa tagaagtttc taaagggggc
     5461 caatcaagtg ttaaaaaaac cgacaatgaa agacaatttg ataggttacg gctttctagc
     5521 gccagctttg ctgctgctga cgatttttct gatcataccc gtaatcatgg taatttatta
     5581 tgcctttact gattattatt tgttaacgcc agatgctaga caatttatcg gcttagaaaa
     5641 ttttaagcga ctgttcgctg atccaatttt tgtaaaaagt atttggaaca cggctaaatt
     5701 tgttgtttgg attattccgg tccaaatagg ggcagcttta ggaatggcac ttattatcaa
     5761 caaaaatcgt aaaggaaata tcttttttaa agtagccttt tttgcgccag tcgtgatgtc
     5821 cttagtcgtt atttcgattt tatggttgta cttgttaaat cctaatgaag gtctggttaa
     5881 tacgctattt gcaaagattg gaattgcttc gcagcctttt ttgactagtc ccaaacaagc
     5941 aatgtatacg cttgttttcg tatcggcatg gcaaggtgca ggatatcaga tgctgctgtt
     6001 tttaggggga atgcaaaata ttccgcaaga cgtttatgag gcagccgaaa ttgatggttt
     6061 ttctaagttt cagcaatttc gctatatcac catgccatta ttaaagccca cggcgatttt
     6121 tattttactt accacattga tttcggcctt taaactaatc attcagccaa tggtaatgac
     6181 tcaaggtgga ccaatgaatt ctactatgac aatggtttat tacatttacc aaactggatt
     6241 tacagaccgt atggtaggct actccagctc cattgcgtta atctttacca ctatgattgg
     6301 tttaattaca attgctcaaa gaaaattggt aaaggaggat gatccagcat gaccaagaaa
     6361 tttggaccgc taatgatcgt agaatattgt ttgctgttcc ttttagcggc attattcatt
     6421 ttcccgatgc tgtggatggt agtttcctct atgaagcctg aagcagatgt ctatcaaaat
     6481 ttagcttcct tcaaagcttt tttacctagt ttgaatccag ctaattggtt taaaacttat
     6541 caagaggtta tttcccggtt cagtgtggga acttatttat taaacagtat tttttatggt
     6601 ttaacctttg cctgtgggtc aatcattgta aactctttgg cgggttttgc ctttgcgaag
     6661 gttaattttt caggcaagaa aattatcttt ggagctttgt tagctctgct gattgtcccg
     6721 atggagacgg ttttaattcc gcaatttacc atcgttaatt cactaggctt agtgaatact
     6781 cgcttggcag tgattttacc agcgatggcc agcgcgttta atatctatct gtttagaaat
     6841 ttctttatcg cgattccaga agaaatcatt gaatcagcga aattagatgg tgcaaatatt
     6901 gttaaaattt tctttcacat catgctgcca atgtctaaac cagccatagc cacagtaggt
     6961 gtcttatcct ttatctccag ctggaatgat tatatttggc cgttaatggt cttaactgac
     7021 agcagcaaat tttcaatgca agtggcaatt actacgatca atactacaca gccagtttat
     7081 atcaatcaag tgatggctgt tttaaccatt gcaacgattc cactgattat tgtttatatc
     7141 gttgcacaaa aatatattct gcagggactt ggcggttctg gaacgggtat aaaataggag
     7201 tgaatagtga atgttgcaaa aacttttaaa ggccaatgag tttattgaga aaaatgctca
     7261 aacagtcaat caagaatacc ggaataaatt tcatttgatg gctccgattg gctggatgaa
     7321 tgatccaaat ggttttgttt attatcaaga ggagtatcac ttgttttatc aatattatcc
     7381 ttacgacagc atctggggac caatgcattg gggccatgct aaaagcaagg atctaattca
     7441 ctgggagcat ttgccagtag cactggcacc aggtgaaagc tatgacaagg aaggctgttt
     7501 ttccggcagt gccatagaaa aggatggcaa gctgtatttg atttatacag gacacaatgt
     7561 tgtggaaggg caagttcgac aagttcagtg tttggcagtt tcagaagatg gcattcactt
     7621 tgaaaaatat gccggaaatc caatcatcgc agaagatcac ttagcttctg ttgcaacgac
     7681 cgaagatttc cgcgatccca aagtgtttca gcgaaaagaa gactatttta ctgtagtcgc
     7741 tactaaaact gcagatgctc gtggacaaat tgtgatgttc cattccaaag atttactaac
     7801 ttgggagttt tattccgtat tgctggaggg aactccagaa caaggcattg tatgggaatg
     7861 cccagacttg tttgaactag atggcaaaga agtcttgatt ctttctccta ttcaaatgac
     7921 tccacaaggc aatgcttacc aaaatacgaa ctcaactgtt gctttcatcg gtactgtcga
     7981 ttggcaaaca ggcaaatttc tagtagagaa ttttcatgaa atcgatggcg gtttagattt
     8041 ttatgcaccc cagacctgtg aaaacgaagc aggccaaaga ataatgattg cttggatgca
     8101 aatgtggcag cgtaaaatac ctacgaatga tctgggccat ggttggtcag gttccatgac
     8161 cttgcctaga gagctgaggg tggctgataa tcaattgttg caacggccag tttcatcaat
     8221 ttatcaagta attgatccgc aggaaaggat tgaatgggcg aagactgaag agaatcgctt
     8281 cttactgaag gacttagtat atgaccagca ctatttacgc ttggaaatca atttaaaaca
     8341 ggcaacgaaa ctagaacttc actatgcgaa gggacccgac catacattac tgcttaacta
     8401 tgatgttgaa cgggagtgct ttactgcttc cagggaacac atgccgtatg atttatcagg
     8461 agctgaaaag gaagtgttga aaaagcgcag tgtgacgatt cctttggaaa ataattgtct
     8521 aaccatcgaa attttccgtg atacttcagc tattgagctt tttctaaatg atcgtctgac
     8581 tatgagtaca actttttatg agacagaaaa aggacaggat tttcttttgc tggcagacag
     8641 tgaagtaacc ttttcattgg aaagcggctt aattaatcta tagaagggag agctcagtga
     8701 tgatttatgg ttcaatcgaa gcaggcggca caaaatttgt gtgtgccatt agcgatgaag
     8761 aaatgacgat caaggaaaga gtgagctttc cgacaacgac acctgaggaa acaatacctt
     8821 tagtcattga cttcttcaaa caataccaag cagatttagc agggattggg attggctcat
     8881 ttgggcctat cgatatccat cgcgattccg ccacttatgg gtacattacc tcgaccccga
     8941 aa
//
LOCUS       DACBYO010000108         8721 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.108, whole genome shotgun sequence.
ACCESSION   DACBYO010000108 DACBYO010000000
VERSION     DACBYO010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.108"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            126..326
                     /locus_tag="IVD26_002558"
     CDS             126..326
                     /locus_tag="IVD26_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6080476.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            338..664
                     /locus_tag="IVD26_002559"
     CDS             338..664
                     /locus_tag="IVD26_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080477.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            817..1869
                     /locus_tag="IVD26_002560"
     CDS             817..1869
                     /locus_tag="IVD26_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAP6080478.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            1945..2163
                     /locus_tag="IVD26_002561"
     CDS             1945..2163
                     /locus_tag="IVD26_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080479.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            2150..4828
                     /locus_tag="IVD26_002562"
     CDS             2150..4828
                     /locus_tag="IVD26_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080480.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            4819..5016
                     /locus_tag="IVD26_002563"
     CDS             4819..5016
                     /locus_tag="IVD26_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080481.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            5020..5631
                     /gene="mobC"
                     /locus_tag="IVD26_002564"
     CDS             5020..5631
                     /gene="mobC"
                     /locus_tag="IVD26_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HAP6080482.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            5616..7007
                     /locus_tag="IVD26_002565"
     CDS             5616..7007
                     /locus_tag="IVD26_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP6080483.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            7223..7537
                     /locus_tag="IVD26_002566"
     CDS             7223..7537
                     /locus_tag="IVD26_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080484.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            7530..8024
                     /locus_tag="IVD26_002567"
     CDS             7530..8024
                     /locus_tag="IVD26_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080485.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            8092..8406
                     /locus_tag="IVD26_002568"
     CDS             8092..8406
                     /locus_tag="IVD26_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080486.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            8505..>8721
                     /locus_tag="IVD26_002569"
     CDS             8505..>8721
                     /locus_tag="IVD26_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP6080487.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDLMD"
BASE COUNT         3408 a         1142 c         1648 g         2523 t
ORIGIN      
        1 caaactatta tagcatgaaa accacaaatt gagtaatatt ttaattgata ttactcgttt
       61 tgtggtttaa aatgtgctta ttaagataaa aaccacaaag tgaataattt gaaaggaggc
      121 gctgaatgat aactcttaat gatcaattca ttagaagctt aagaagacat agagccgatc
      181 ttatacttac taaaaacgat gcagcaaaat tgataggtat aaatcggaaa acatatgtca
      241 aaatcgaaaa tgggagcaaa gaaagtatta gagcatctac ttatcaaaag ttggtaaatt
      301 ggttacttaa tgatttgaaa atctaaataa atacaacttg gcgagttggc tgattgaaga
      361 aatagaaaat gagaggagaa aaataatgga tgcaggaatt acagtaatgt tagataaaca
      421 acaaacgaat caattgaaaa attatgtttt tgaaatgaca aaagaggcta ttgatcaagc
      481 aagaattgat accggattag aaagaccatt tctaaaagga aaagagatgg ctaaatattt
      541 gaatgtatca tatacaactt ttttgaaatt taaaagaatg ggattgccag ttattttatt
      601 agaaaaaatg gagttgtttt caaaagaaga atgcaaaaaa tggatattga gtcatcaaat
      661 ttaaaaaaca cctcgttttt taaatttgat gaagtagaaa aaattaaaaa gagtgttccc
      721 gtcagtttgc agatcggggg aacactcaat aataaagttc tgagaaaact ttatttgaat
      781 ctattatagc aaataaaatc agaagcaggt gtgacaatga atgaaaaaga agttgaaagc
      841 ttagttgaaa agcaaggcta ttctaattct gatatatatg cagaattata ctatcaatat
      901 cctatttttt taaacgtaaa tgaaaaatat aagaaaatga aactaagttc taagttagtt
      961 tatatgttac taaaagatag aaatagactt tcattgaaaa ataacttgta tgatgagaat
     1021 caaaaaattt ttttgatatt tgaaatcaaa aatctcgtag aaatttcggg aatgtcaaaa
     1081 aatacaatct tatcagcact agatgaactt caaaaagtta aacttcttgt gaaaagaaaa
     1141 aatggcttca ataaaagtaa aatgcaaatg ttcccaaatt tttattattt gttaaagcct
     1201 gttctgtgca aagatgatgt ttataaaatt aataagataa cccatcaaga aaatagacaa
     1261 aaaaacttga tagttcaaaa tttgaactat ggaacaaatc aatattctgt tgatagttca
     1321 aaatttgaac tatgcgacac atcaatgaaa acaagagaca aaaacaattt tgctgatagt
     1381 tcaaaaaatg aactagaatt atataagtct tataaagata gtaaagatat taaagaatca
     1441 cataatgatg atcttcttga atcactttca actaaaaata ataaattaga tgaagaattg
     1501 atcgaaacat ttattgaaga aaatcttctt aaacaaatat ggggagaaag tattgtgaat
     1561 tgcttaaaac tggctagcaa tagtgattat cgtcaattcg acaactggta caaaaaattc
     1621 aaatatgcga ttagatctgc tgaaaaagaa caaaaaattc aactgaaaat tatctatgaa
     1681 atttgtaata acaagtattt tgtagatcat gttagagaac agctatcaat gactttacgt
     1741 gacttgatac gaagagcaaa aacagatcat cgtatcaaac aaaaagacga ttatatcttt
     1801 gcttctctaa aaaataaagc gttagaacta attgaattgc aaatcagcga aggaatagat
     1861 aagcaataag aatagaattg agtcaaatga aatggagggg tatctccact tcatttgaga
     1921 actttgaata taggaggggt tattttgatt aaaaatcgtt taatagatca agtttggtgt
     1981 ctagatcaaa atacagatag tctcgaatta atcgagacta tttgcttcaa cactatagtt
     2041 ctcgatttaa gagctgaaaa tgataattgt gtaactcatg tcataattaa tcaaaaaatg
     2101 gctcagaagc tctctgagag cctcagaaaa tgggctaagg gaggtaacga tgaaaataat
     2161 tgaaaaaaag attgccaata aaaaaataaa ttggttggtt gttaattttc ttgttctgat
     2221 agctatgatt atttttacaa gtaatattgc tcatgcgagt attttcaatt ggtttgatga
     2281 cacaaaaagt caaacagagt ttttgaataa ttctctttat agaccttacc taaaaaagta
     2341 caatggagat ttccttagtc agttcgggat ttggctcgga tgggctgtgg taaaaggcat
     2401 gtttactgtg acagattcga ttcaaaatat gattccagat gtgctggatt tgttcaattt
     2461 cattgaaagt acagggctaa ataatgttta tcaatcagcc gtaaatacaa ttgtcattgg
     2521 attaatgatc ctttcattga tgtttgttgg ttacaaaatg attactggaa aaggaacagt
     2581 ggatttaaaa tcggttggaa tgaacgtagt gatgtctata gcattaatac ttttaatgcc
     2641 aaccatgatt tctagtggta ttcaatttgc taaaacattt tataaggact ctactacgat
     2701 tacaaattca gatgacggag tcgcttggtc attgataaaa caaggagtaa cagatttagc
     2761 atatattaat aaaacagatc agtactcaag cattgataaa acggaggatc gaaataattt
     2821 aacacgaaaa aattttcaac agacggatct cacacaagtg ttaacggata aagtgattga
     2881 taaattggaa aaagaaaatc caattgcgga caatcttcgt tatgaattag ttgaaaattc
     2941 taataatgaa tttgttgcta caaagttttc tgacaacttc ttatcaacat tttctgatag
     3001 cttgaaatca ggctattacc gataccaagc aaatctatgg gggatttcaa ttgggttgac
     3061 agcgttagca atcgcctatg tgttcagcgc gtttgtgatc attacagcaa tactagaact
     3121 tgcatttaaa cgtgtgttag gtgttcttgt ttttgcaaca gatattgaga caggacagcg
     3181 ttcaaaagtt gttctatcag atattctaca atgttactta actgttgggt ttcaaggatt
     3241 tgggttatca atgtttgcta tgtttatcaa ttttctgaac tcaggacaag gtatctcaac
     3301 aaatattttt ataaaaacaa ttgcttatat ctgtgccgtt tttgttttaa tcaaaggcag
     3361 tggaacagtc atgagatact ttggtgttga tattggactc aaagaaggct atgggcaact
     3421 tgcttctgct tttggaatgg gcgcaatgct gtttagaaaa ggatcaaatg gatttaatcg
     3481 tgctaaagga agcggagaag gagaagatcg aaaaccagaa aagaatttcg gcgaaactct
     3541 atcaaaaaaa gctggcaaaa ctggaagagc tttgggatat gcccatgaac gtggattatc
     3601 cggtttagct tcagatggag ctacaatggc tagtgaaaga gcaacaaaac catttaagag
     3661 tatgcgtgat atagctaatg ataccaagaa taagtttaaa gaaggtttag atgatggtac
     3721 agtgtccgct attaataaaa atagcaaacc tatgttagct aaaaataaag aagatgaaac
     3781 tggaaaatat gctgattccg tgccaacacg tctttcagat agaaaagatg gtgctaaagt
     3841 tgaaaatgcc gatagaatta tgtctagttc tgaacgtatg cgtgaagcaa tgaaaaataa
     3901 tgctgaatcg aataataatc ctgcaagcgc aattcagcaa aaagtccaac aagatattga
     3961 agaacgtaaa aatgctatgc acggtcaagc taagtctgct gaagaattaa ttaatcagaa
     4021 gcgtcatgaa gcgaaataca cgcctgaagc aatgaatcgc gaggaaataa tgttaaggaa
     4081 acgtgtagaa gggcggacag gcgctaatat tgacggaaaa gaagcgttga ccaaagaaag
     4141 aattcaagaa gctaaaaatt caaatacagg attagaaaaa ttagtcaaag aaaatccaca
     4201 aaattctaca agtagtcatg gtggccgatc agtagatgtc cgagaaaata ttcaaggttc
     4261 actgaatggt catgttggac ggaatgttga tgtaagagag aatttacaaa gttcttcaaa
     4321 tgctcaaggt actaagacaa ttgatgttcg agaaaatctg caaagtagca gtacaagtca
     4381 accaaaaaca gtagatgttc gagaaaatgt acaaaattct acaagtagtc aagggtttaa
     4441 atcagtggat gtccgagaga atgtgcaagg tagcagtgca agtcaaccaa aaacagtaga
     4501 tgtccgagaa aatgtacaaa gttctacaag tagtcaagga ttcaaaacag tagatgttcg
     4561 ggagaacatt caaaaagata gtggagaaat gaaagaaaaa acacaaaaaa tcaatatcgt
     4621 tgaagacaga aagtcagcga aaaaatttga ttcaaatcat gaaacagtga ttattgatag
     4681 tgaaatccgt gaaaatgata agggatcaaa atcaagacga agattcactt atgaagacaa
     4741 tgagttattc agagatacac ttaatgatcc taatccactt ttcgataatt tattaagaaa
     4801 taaaaggggg ggattgtcat gcaattaatt ctaaagatta gtacgcatga tttcttagaa
     4861 cttgacgaat tatgtgaatc agtaaagaac gcaacaaatg aaaaaatcac ggtcactaat
     4921 tatattgaac tgatgattca agaagaatta aagatgaaaa atgaaataga gagcaatttc
     4981 aaatgttgct ctctagaaaa aaatgtgagg ggataatcaa tggatgataa acaaaaaatg
     5041 tacgaaaaaa atcgcaaaca tagtgaggcc ttaaattttc gtgtcgataa aaagacttat
     5101 cttgaactga cattgattgc aaaacaaagg ggaatttcta gagcagacgt ttgccgtgag
     5161 cggttaaagg gactcaaata tgaaccgccg ttgttagctg aagatgatag ggtagtttta
     5221 accaaacagt taaatcaaat tggtaacaat ttgaatcaag cggtaaaggc attaaatatc
     5281 attgctaaat attttagaga agaatctgaa gataaaaaag aaaagagcct acattttagt
     5341 tttgatgcta gccgttacaa catttttaaa gatgaacttg cgaatagcat agcaaaaaag
     5401 ttgatgatta gttatccaga tgacattttt ttggagtcca atcggagtgc cccctctttt
     5461 tttaaattat cagaagtaga aaaagaatat ttcgaatatt ggatagaaaa gcaaactaga
     5521 ccgggtacga aagaagagta ttcccaaaaa gttgatcgga atttaattca ctcaattcag
     5581 attattgcaa gtttaaaaga tgaggtgaaa caactttggg agctactata acatcgaaag
     5641 gacgcaagaa aaatttatcc tcgctattac aatatgcagc taatccttca aaaaaagaaa
     5701 aatgtgttgc agtctcagga ataaattgta gtgatgatag tgaggaagca ctgcaagaaa
     5761 tgaatttagt acgtaccaag atgaataaat ctaaagatat agcacaagcg tttcatgtta
     5821 ttcattcgtt tgataagagt acttctaaag agttaagtat tgataaaatg cacgaaatag
     5881 ctgtcgaatt tgcagagaaa gcttttccaa attcgcaaat cattgttgca agtcacaatg
     5941 ataaagatca ttttcatagt catcttgtca ttaataatat taacatggaa acatgtaaaa
     6001 ggttgcgtat tgaccctaaa gatttagaac taatgcgaaa aattaacgat caagtcctca
     6061 atgaacatgg tcttgaatca gtgaataatg agtactatga aaacttagaa aagagaacca
     6121 atctttattc aaacgatcct tctaagatga aatatggaaa aattaattat caagagtttg
     6181 tgcaaaatgc gatcgaagca acgttggaaa aatgcgaagt gaattctttt gaagattttt
     6241 cggatcattt ggcaaaagaa tataacattg aagtttatca attttcaaaa acaaataaca
     6301 aacttggcta tgttctttac aaacaaggtg taaatttcta tgagcgtaga ggtgagttaa
     6361 ttactttagg aagagataaa caatctagaa aagaaaaaag tcagtatgtc gaacgtactt
     6421 ttagtgcaag aaagttaggg aaaagatatt catttgaatc tgtttctgaa caacttgaaa
     6481 agaatttaga agaatcacat ataaaaaatt tttttaatat ggaaagagag caagttatgt
     6541 cgctaattag tggagtaaat tacaaaactg gtgagttaaa tgtaccgttt gtggaattag
     6601 attccatcgc acaaaagcaa tttagcgacc gtgaaggcga tgaaaaattc attaaatatg
     6661 atgacttctt gcgagaggta gacaagcatt ttgtaaatac aatgtcttta gaagatgatc
     6721 aagaatacac gattaaactt catacggatg tgaatcctca aactttacgt agtgcgaaaa
     6781 gtaaaacaat ttctattaaa aagactgatc agaaagagtt atttctaccg gcaaagggtt
     6841 ttgaaaattg ttctcataca ccttctgcta aacagattca ctatcaaatc agtcgcataa
     6901 tgaatgacga tgtaaaaatg tatcgtgcta aaaaggatta tgaattcaca caacaaatga
     6961 ttgaaaatca gcaaaaaagg caacaaaatt ttgaaatgga attctgaatg ggcttgttag
     7021 tggactttcc agttttttgc ctatgaagag ttgcttggaa agaagcagtt tttaggacat
     7081 acgccagcta cccatctact tgccagtcaa tccgccccgc tcacgctagg ctactttctg
     7141 gcaagtcaga tggcgggtaa atctctgagg gagcaagctc cctacagact ccctcccaaa
     7201 aaaagaaagg tggaagaaaa aaatgaacta tccatatttt aaagtctcgg cttcagaaga
     7261 aactaaagaa atattcaaca atttttacaa ccaaaacaaa ggaatttttg gttcaaaggc
     7321 aaatatgttt cgtgttatgg tttcaaattt accagtgtta gctagtccat caaataataa
     7381 atttaatgat cctgaaagca ttaaatttga acaaaaaatt tcagaactag aatcaatgat
     7441 aagtaatgaa gtaattgaaa agctggatga cattgatcaa aagttatcgt attctctaaa
     7501 aaacaaatac aaaacggagg agaaaaaaga tgtttaaagt ttacttcccg tttcagtggc
     7561 tcgttaaagg aattctttta gtgctactag gattgattct ttttggaagt tatctaacaa
     7621 ttaaagccag acattttcca gaagaaaagc caataaaaat tgtaacaaaa gatttaaaaa
     7681 taggtgaaac ttatcaggca gatggggttg aactaacatt taaaaatatt gaagtgaccg
     7741 aaaaaagaaa tgaatttgca caacatgatc gtgtattaca agtgacctat acacttataa
     7801 atgatacaga aaatccgata cgtccacaac aatggtcgat tgaaaataag gatggtgaag
     7861 aactttatga gtatgatatg atattggata atccagagta tattgaaagt ggcaaagaag
     7921 aaacagtaaa ttactattat gaattaccga ttgaaaggca ggactaccaa atcgtagtac
     7981 gtagagagaa tggttacata gttgggttgc catttacttt ataagtttta ttttgttagt
     8041 agtttttaag gtaatatcag ttttgtgatt tttgaaaatg gaactgggag aatggctgag
     8101 gaaaataaag ttgttccgtt tgaaacatta gtgataaata aggaagagtt tgagcaactt
     8161 tttcttgatt tttttattca atatgacatg atttatgatt ttagttcgtc actagattta
     8221 tttgaattag aagcagaaat aatagaaaac agtcgagaga agaatggtaa aatcattatt
     8281 tcagtagaaa aattcaatga attattctca caaacatttg aaatagatcc agactattat
     8341 caaccacaag aagtttttcg agagtttaga aataagatta ttggttttag tcaaactaca
     8401 aaatgaaagc ttaataaagc aagtgttgat agaattattc ctcaacgctt gctttatttt
     8461 atgggcactt cataatagag gtatagagaa gagaggtatt cattttggat actattactc
     8521 caacaaactt caaagaaaat ataggtaaag tgttgcaaga agtagttcat tcaaattctg
     8581 aaatagaaat tactagggat tctaaaaatg gattgaacga tggcgtcatt atgatttcta
     8641 agagaaaatg ggagttgtta caagaagaac tttatttaca acgaacgggt acatgggctt
     8701 atgtatctga tttaatggat a
//
LOCUS       DACBYO010000109         8217 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.109, whole genome shotgun sequence.
ACCESSION   DACBYO010000109 DACBYO010000000
VERSION     DACBYO010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.109"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            263..1900
                     /locus_tag="IVD26_002570"
     CDS             263..1900
                     /locus_tag="IVD26_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAP6080488.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2045..2785)
                     /gene="truA"
                     /locus_tag="IVD26_002571"
     CDS             complement(2045..2785)
                     /gene="truA"
                     /locus_tag="IVD26_002571"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP6080489.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(2976..3611)
                     /locus_tag="IVD26_002572"
     CDS             complement(2976..3611)
                     /locus_tag="IVD26_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAP6080490.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3758..4999)
                     /gene="sstT"
                     /locus_tag="IVD26_002573"
     CDS             complement(3758..4999)
                     /gene="sstT"
                     /locus_tag="IVD26_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAP6080491.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5197..6193
                     /locus_tag="IVD26_002574"
                     /pseudo
     CDS             5197..6193
                     /locus_tag="IVD26_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6209..>8217
                     /locus_tag="IVD26_002575"
     CDS             6209..>8217
                     /locus_tag="IVD26_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP6080492.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
BASE COUNT         2697 a         1520 c         1264 g         2736 t
ORIGIN      
        1 aaaagataaa tcacctgttg tataaatttc ttgagcattt ctcataaaat ttactgaata
       61 taaagtacta agtaagataa gaactactaa aagaaatgct tttttactta ttttcataga
      121 tttgttgttc tcctttttta attctatttt cagtatacta gaattgtctt tttttaataa
      181 gttttgcgtt aaatttttca tagcactagt atgatatact agaaaagaat caatttttat
      241 tacttttaaa taggagaaaa aaatgaaaaa aaacaaaaac caaataatag atatcatttt
      301 tatgttattt ctaagttttg cttacgtcat ccctctattc atgtctatgg gaatctatca
      361 tagtgtcaat caggatactt actttcattt atctcgaatc ataggactag ataatgtatg
      421 gagttctcca gtaaacttca ataacttcga tcatcatgga acaatgatga atatttttta
      481 tccatggctt actctttatc cagctttttt attttataaa atgatgggaa atcttgtttt
      541 aagttataat atctactatt tttttatcac ttttttaaca atggtcgttt cttatttttc
      601 tatgaaacaa ataaaaaaca atcgttatat ttcgctgtta ttttcgatta tttatacatt
      661 ttccgcctat cgtgccattg acatattcca tcgtgcttca ttgggagaag ctgtcgcttt
      721 aacatttttg cctttgatac taatggggtg ttacgaaatt tatattagag attaccaaaa
      781 atggtactgg ttgtctattg gcatgacgct agtagtgtat actcatttac tttctgtcgc
      841 tatggtttct gtatttattg gaggaacgtt gtttctttct ttttattttt gggaccaaaa
      901 aatcgctaga ctcttaagtc ttttaaaagc taccgtcctc accttttttt taagtgcggg
      961 attcttaatt ccttttattc aacaatctag agcacaagaa ttgaaagtcc cactgggaaa
     1021 agaattaagt ggtatggctc ctagtgatat gctgacacac attttaaata ataactataa
     1081 caactatact attggattat tcttatttct cggattgatt ggtgctttta tttttataaa
     1141 aaaattaact gctgatgatt tatttatttt ctttcttggt gtatttgttc ttttttgttc
     1201 aaccaattta tttccttggc aactttttaa ccatacacca gttaagagtc tacaatttgt
     1261 ctggcggtta aatggttttt cttctttatt tatagcctat acgatgagta tagtgatcta
     1321 ttatattttt tctactaaaa ataattcatg gaaaataatg gtctttacgt ttcttgcact
     1381 aatattgcat ctctcaggag taagcaattc tatccatgct aacaaagatt cattaacact
     1441 tatagcacct gaagacgctg ttgctatagc tgaaaattac aatcatactg attatgcaaa
     1501 caaagagtca atctatcatc ctgatatgat taataatgat caatatttac taggtaacca
     1561 ggaaataaat ccaacaactc attttatgag taacaaactt acaattgaat tagataattc
     1621 gaataataaa aatactgtct tgacgacacc tatttatcgt tataaagggc aagtggcttc
     1681 tattaatggc aaactagtac aaacaaaatt atctaagttt ggcacaactg aattaactat
     1741 tcctccaggt ataaataaag tcgttattac ttatcagtac acaaaactag caattgcttc
     1801 aagatattta tctatcgtta ctttgatttt atttttactt tatcgattta ctttttctaa
     1861 acaaaaacaa ccgagaagag aagtacaaca ttctcactag atttttattt aagaaagact
     1921 ttttagctgt acacataaac aggctaaaaa gtcttttttt atatttcttt aatttgcttc
     1981 atacattatt taacatcgat atttatactg tgaaacatgc gtttcatcca ttatcaaagt
     2041 atttttatcg ataataaact tcatccaaaa acagaccttg tgcagggacg gtttctcctg
     2101 catgttgccg cactttgctt tcaaatattt catcgattgt ttctatcggc atggcacctg
     2161 tgccgatttc tagtaatgtc cccatgataa tccgcaccat tttatataag aatccgtctc
     2221 cgacaaaagt aaaatgaagc atttctccct ttcgttcgat agataattca tcaatcgtac
     2281 gcactgtgga tttttttgat tttttcaatg cagaaaaacc aatgaaatca tgtgtaccca
     2341 ctaatttttc gcaagctgca ttcagcttgt ccatatccaa ctcttgaggg aaataaaagc
     2401 tgtggtttcg ctcaaatgct gaaggaatca cgttgttcca aacataatag ctgtattttt
     2461 tgcccaccgc attatatctt gaatggaagc gctcaggcat ttcttcgatt cttttgatga
     2521 caatatcccg cggaaggtaa cgattcataa agtcgatcat ttctgccagt ccaatttctg
     2581 tgtttgtttt aaaatttgct acttgtcctc gcgcatgggt gccagcatct gttcttcctg
     2641 atccaataat ttctatctct tcatttgtca tctgatgcaa tactttttcg atttttcctt
     2701 gaatggtttt atcgtcatct ccaagtcttt gccatcctga atatcttttt ccgtcatatt
     2761 cgattgtcaa cttgatgttt ctcatatttt agtggctcct ctgtcttcca tttggtcttc
     2821 tctctacctt tttaagattg tagcacaaaa tatagctcct ttcttctcta aaacagaagc
     2881 tatacaagaa aactgtggaa atatatattt cagaaaaaca aaaaacagcc accggatgaa
     2941 gtatccgctg actgttcaat ttgacggctc aagttttact gtttgagatg caagatactc
     3001 aaccaggcaa tgggcacata attaaagaaa aaactgattc tttggcaaaa acctatttta
     3061 ttcagtaatg gccaagaatt tatagaagga attcttgcca gtccataaat cgccgcaaaa
     3121 agcaaactga tcacagacag tccaaggtat aagtggctta cgtccatttg cccatttttt
     3181 cgatagatca agaaaagaag aactggaaac aataaaaaac cactgtaacc taaacctgat
     3241 ccgatattat ggacccatgt cgagacattc cacgaagatt catgggtatt gatactgaac
     3301 aaacctgtaa agatacaatc acctatacca tagaacgcga tggctgctgt aactagggta
     3361 gctaacacac gagatgtact tacaaatgca gcatacaatg caggcaatga caggatgaaa
     3421 aagatccctg aaaccacaga ccaaataaga aacgcttttc ttacaggact ggaaacctct
     3481 ccaaatacac tgatcacgct cttcatttga tctaattcag gataatacaa tcctaatacg
     3541 tacggagtca aaaaatcact cagcacgcct aataataaaa agaaaaaacc aaatttacgt
     3601 aaaaaatcca tgatacgcct ccaataacaa ttacctatgc ttttaattgt tattataagc
     3661 gactttatct tgatttaaca gaaacctcta tttacacgaa catctatata actcattaaa
     3721 aactcgaatc attttaaaaa tactaaatat ctaacgttca acgttcactt aatccatcta
     3781 aacaatcttt caatttgatt ttttccccac ttcttttacg cgcgcctagc tctcctattg
     3841 cagtaaacaa cagatcactt gacgaattta aggcagtttc cattgaatcc tggataacac
     3901 cgataataaa tccaataccg acgatttgca tcgcgacatc attagagata ccaaacaaac
     3961 tacatgctaa tggaatcaat aacagtgaac cgcccgcaac acctgaagct ccacaagcag
     4021 ctaaagcaga caaaatacat aaaaggactt tcaaaacaaa aggtgcttca atccctaaag
     4081 aatgtacagc agtcaacgtc atcaaggaaa tggtaatcgc ggcaccgccc atattgatcg
     4141 tagcacctaa cgggatcgat atggaataag actcttttgt caatttcaat ctttcagcca
     4201 acatcatgtt tatcgggata tttgcggcag aacttcgggt aaagaaagcg ggaagtgcgc
     4261 tttctttcaa acaaaagaaa atcaatggat agggattttc tttaataaac aaaaacgtga
     4321 ggaatgggta cacaactaat gcgacaaaca gcatcgtacc gatcaaaaca agtaaaagct
     4381 gcagatactc tgccaatcca gctattccag tcgtagcaat tgattgataa accaatccta
     4441 aaatccctat cggagcaaat gcaataatca cttgtacgac ttgtgacaac gctatagata
     4501 tctgatccac caactctttt gtcgattctg aacgtgctcg aaaagctagt cccaacaata
     4561 cagcccagaa taagacgcca aggtaattcg catcaataag agattgaaca ggattttgtg
     4621 tgacattcgt caacatagta gataaaacac tttccaaact ttgcggtgct ttttcagata
     4681 ctgtttcttg taaagtaata ggaacagtaa aaattgaact tacaataact gctacaagtg
     4741 cagaaagcaa tgttcccact aaatataaga tcaaaatagg cttcacgaat gtcttattcc
     4801 caattttatg cttggcaatt gacgccatcg tcaagaaaaa aaccagaata ggtgcgattg
     4861 ccttcaagca actgacaaac aacgttccca atattgaaat aaatgtccat gtggggaaaa
     4921 agataccaaa caatattccg actaaaatac caacaacaat acgttgaact aacgacatat
     4981 ccaaaaactt ctctaacaaa tgaccaccct ttcacaattt taacaatcat tgtatcattt
     5041 tatgcaaaga aactaaaggt ataattttct aaaaattcta acaatacaaa caaccatttc
     5101 ttgctaattt tgtacttttt ctgtctacac gttgtttttt gagatattct aagttaggat
     5161 gttattaatg ggcaacttat caggaaacgt tttcttatgt ttttgtccaa tttttttgtg
     5221 aggtgtttat tcttgaaaaa aataaagaag gagagttatg gcttcctgac aatctttgtc
     5281 gcttgtataa tgatggtttt acagcgtata ttgatttcag cagtcactat tcctacatat
     5341 gcaacaaacc ctggtcgatt ctacatctat acatttttac aaacttccgt tgttattggt
     5401 gcaaatttga tcccacttta catgggttac caatatcaaa aaatcgcccg tttaaaagtt
     5461 ttacattatt taagtcgttt tgcctttata ttcctaatag ccacactagt ttgcaatatc
     5521 ttttttttac gtacaagctg gcagcttgaa tattcgtgat tattggctta tcctaacacc
     5581 tatcagtcag aattacttta cttatgctgt ttcttgtact ttgctttttt gtagtattcc
     5641 ttatacagtt ggatttttaa ataaattatc gaaaacaaca attaaatatc tactattatt
     5701 tttaacaatt ggattagttg gctgctctac tctatttaat aaagacccgt ttgcattaca
     5761 gaatggacag agtattttat ggatttttta tttattttta atgggttatg gtttgaaaga
     5821 atggaactgg aaagaaaagg tccgctataa gcttcctcaa gtatttatca gcttgattgt
     5881 tttattcggt ttgattattt tgatgacaca aatttcactc atcatcagag gaaatacaga
     5941 tacagcgctg aggttttcta aaccatattc tctcttcgca atgtattata ctttctcttc
     6001 gtttttattt ttagaaatgc tatctgataa attaggtata aaaggaagag gaaattttct
     6061 tgctgtattt ttgattgtca ctcaagttat atgtaatttc cctttagttt cttatcgcgt
     6121 atctacattt atgaaacgtg aatttccaaa ctcagggaag gcatggctga taaatatcgg
     6181 gcagtttttt atttgctatt tattagcagt gtccctccta gttatctttt tattttatat
     6241 acaaaaaatc cgtttcattc atcgtttcat cgaatacttc gcttttgatt cgattgaaca
     6301 attaactcag cgttggaaaa aaagaattca ttggcttttt gttcataaaa gttatttttt
     6361 agttgcagca tttttttact gctttacctt cgtgcagatt ttcgttttag aaccaaaaga
     6421 aggttggaaa gaaactatcc aggttgcctt aaaaatattt actcagcgac aagcacccat
     6481 gatcctgaca atcatcatta ttatgggatt tttcttctta ctattgttga tttccaatcg
     6541 tttttggtac gccttgactg ctaccttgat cattaactta ctgctcacta tttcgacagt
     6601 aatcaaaatg gaaatgcggg aagagcctgt ctttccttca gatttaaaaa tactgaccgg
     6661 attgtcagaa ctattatcga tggttagccc agtcttatta atcgtgggcg gattgatcct
     6721 tctcctatta ttgattacta gtattattgt acaacgtaga ctacaaaaac agtattcctt
     6781 gaagattcat tggaaacgtc gatttatcag tatcgctgta ttattaggat gtttttcggg
     6841 tgtctttttc attaatcaca aaaattcgcc ttctttcttg ctgtttaatt tatttaaagt
     6901 aaacaagact ttctttaacc agcaaggcgc cgtaaaagat aacggaccag tcattcaatt
     6961 cctaaacaat atcgacatta aaatcatgga agaacctgct ggctattcga aagaaaaaat
     7021 taatggaata atgaaaaagt acaacacaaa ggcagatgaa atcaaccaaa caagaagtga
     7081 ctggttaaac aatcagacga tcgttctcaa tttaagtgaa agcttcagtg atcctgcacg
     7141 tgtccctaat ctgacagtac ctacagaccc tattccttac atcaaaagca ttataacaga
     7201 aggaacagga ggattgatgt tatccgtcgg ttatggtggc ggaacagcta acatggaatg
     7261 ggaaggactg acaggcttga gtatcagtaa cctgtctgct tcgttagtta caccttatac
     7321 ccagctagtg gagcgtcaga aaataagtcc aaatattacc gatctattcg atgaaaaaat
     7381 agccatccat ccttttacag ctgctcttta tcgcagaaaa caagtgtttg ataaatttgg
     7441 ttttgacagg ttctattatt tagacagtcc ggataaatta acttatacgg ataaaataga
     7501 acaaagccca cgcatatcgg atgattcagc atacaaagaa accttgaaag ctttacaaag
     7561 caatacagaa acgtcacaat tcatccaatt atccactatg caaaaccata tgccttatga
     7621 tgattactat agtgaattga actacactgc tgaaggaact gctgtcattc ctaatagaag
     7681 aaaagaatta caaacttata tgcaaggcct tcactatacc gatacagcag taaaaaaatt
     7741 catccaagaa atcgacaaaa tcgataaacc gattaccttt gttttttatg gtgaccattt
     7801 acccgcaatc tatagtggga atgattcgaa aaaatatgga ttagaacagc accagacaga
     7861 ttatttcatt tataacaaca agtatagtcg tgaacaagca gctacgttaa ataaagaagt
     7921 tgttgctcct aataactttg gtgctatggc tcttgagcat gcgaatatca aagtaactcc
     7981 ttactatgcg ttgttgacag aagtatctaa tcatctacct gcattaacaa ttgatcctac
     8041 agaaagcttg tctaatcgtt ttaatggaaa acaggtcttt gttacagagg atagtcaaat
     8101 tatccaagaa aaaaatttaa ctgagaaaca aaaagaaatt ctagaagatt atcgtctgat
     8161 acaatatgat cttgttgcag gtaaccagta cagtgcaaca tgggcgacac aaaaaat
//
LOCUS       DACBYO010000110         8105 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.110, whole genome shotgun sequence.
ACCESSION   DACBYO010000110 DACBYO010000000
VERSION     DACBYO010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8105
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.110"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..3029)
                     /locus_tag="IVD26_002576"
     CDS             complement(<1..3029)
                     /locus_tag="IVD26_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297336.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HAP6080493.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPE
                     DKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHKVI
                     FTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEF
                     VSSATKLDDKSDADKYNPEGQKVTTELNKEPDASEGIKNKEDLPKDTKYTWKEKVDVS
                     AAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKY"
     gene            complement(3646..3951)
                     /locus_tag="IVD26_002577"
     CDS             complement(3646..3951)
                     /locus_tag="IVD26_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080494.1"
                     /translation="MLNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDA
                     KISSYLFFLIHDEFMDYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(4096..5300)
                     /locus_tag="IVD26_002578"
                     /pseudo
     CDS             complement(4096..5300)
                     /locus_tag="IVD26_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
     gene            5994..6380
                     /locus_tag="IVD26_002579"
     CDS             5994..6380
                     /locus_tag="IVD26_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP6080495.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            6478..6669
                     /locus_tag="IVD26_002580"
     CDS             6478..6669
                     /locus_tag="IVD26_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6080496.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            7183..7515
                     /locus_tag="IVD26_002581"
     CDS             7183..7515
                     /locus_tag="IVD26_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6080497.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7812..7967
                     /locus_tag="IVD26_002582"
     CDS             7812..7967
                     /locus_tag="IVD26_002582"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAP6080498.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLTDHHITHSMSQTGTPVDNAVIE
                     AFHRSIK"
BASE COUNT         2613 a         1473 c         1173 g         2846 t
ORIGIN      
        1 tcatatttat cggcgtcaga acgattgtct gtcactgtaa catctacttc aacttcatca
       61 gatgatccat ctggatatgt cactacaaca gtcccttttt tatttccagc tgcgctaaca
      121 tctacttttt ctttccaagt atacttagta tcttttggta aatcttcttt gttcttaatt
      181 ccctcagatg cgtctggttc cttattcaat tctgtagtca ctttttgacc ttcaggatta
      241 tatttgtcag cgtcagattt atcatccagt tttgttgcac ttgatacaaa ttctgtatca
      301 tctgctgtaa ttggttgagt tgcttcttct ggccatttcg catctgtata accatctttt
      361 gctttcaaca ctggaagttt atcttctggt aagcttacgc cgtctttcac tgcaaagacc
      421 gttgttccac tttcaatact tgttccttcc cctgcggtga agattacttt gtggtagcct
      481 gcaggaatgt tttctcctgg attttcaatg atatcatcca gttttgttgc acttgataca
      541 aattctgtat catctgctgt aattggttga gttgcttctt ctggccattt cgcatctgta
      601 taaccatctt ttgctttcaa cactggaagt ttatcttctg gtaagcttac gccatctttc
      661 actgcaaaga ccgttgttcc actttcaata cttgttcctt cccctgcggt gaaggtcact
      721 ttgtggtagc ctgcaggaat gttttctcct ggattttcat aaatatcttt acttacagtt
      781 actgctaaat cggtcgtgcc tacagaacca tcttggtaaa caattttaat aggaattgtt
      841 ccagtaatcg gctccgattc tcctacacct ttagctggag tgaatgtaac aataccagta
      901 tttgcatcaa cacttgcatt accgaagtcc ttattataga catctaaaat tgaaaaggca
      961 tctttagcta aaggaacatc tggtttatca aatgtaggtt ttccactttg aactgtcgtt
     1021 tctggagttg ttgttatagg tacgtatgtt gcatcatttt ccatagcttg agaagctttt
     1081 acagcaaact ctacatccac gtcgaaagtt cgatttccga tcttaacagt tacaatacct
     1141 ttcgtactat cagtaacgtt agaagtatca ggctctgttt tccatgaata ctctgcatct
     1201 tcaggtaagt ttttattatt ccgaattgat tctttagcat ctggtttaaa tccaactacc
     1261 acggtttgtt tatcaaccgc ttttggtgat tccttaataa cggttgaacc ttcttctggt
     1321 ttatcaaaac ctggagaaac gatttggatt tttaattcat ctttcgcgat taatttactt
     1381 gaatctacac ccgtaaattc aaattctaca gtatctgaaa ttggagcccc atctttttca
     1441 tttggagcga tagttttttc tgctaataca gtaccttctt tatcaacaag ttgggctttg
     1501 tgacctgttc ccgctaactc gtggatgaat actttcccct taactgttgt gtcaacatca
     1561 tatacttctt ctaattcagg tttcccgata tatggattcg tgtctccgct ctcttcttta
     1621 tcgtcagggt ttccatcacc atcaatatct tgcaaataat aataacctgt tccataagtg
     1681 ttctggatta attttttatt cgtatccgac aaccaagaat caaagatgaa atcttcacca
     1741 aatggtttat tttcttcaac ttgtgctgtt gctttcatat cttctaagat ttcatctaat
     1801 ggcttagtca attgtaaaac atatcgaata acgactggac gtggacttgc attagcaaaa
     1861 tcaataagtt tggtaagatc attatcagta attgaaccta caccataatt ttcatgatct
     1921 ttgcgccgtt caattgctaa atcagccact tttttccctg attcaaaaga aacatcatat
     1981 gttactttgt cagcctgaac catgtgcatc tgtatacccg ctacatatgg aactaatcgt
     2041 tcatcaattt tgtaattagc ataccaaggc gtgccctttg cggaagctga atatgagaaa
     2101 ttataatttt tcgttaactt atgatctaag attatagctc cattagcacc tgtggatcct
     2161 gaaccatctt ttgtttgagt attaggttcc tcatattttg cacttactga tccatgttta
     2221 aactggtcag gattattttc agatacatct aagctattat agaaatcatc tgaatctgtt
     2281 aaaaagtagc ccgtactatc aatacctggt acaattttat catcgtcttg atgacttacc
     2341 aagtagattc gatacattaa acgatcggtc ttgagattgt ctatgcctat ctctttaaaa
     2401 atttcatcta agctcttttc aaacgtaatt accccattag gagcagtttg tgtatcagtt
     2461 gtttcagccc cagcaaataa tccatcactt gcacgaatat aattgacctt ccaaatattt
     2521 gtaggtctac ccagcgaatc attaattctt acaaaggtcc gtctagaaga tccaattcct
     2581 ttctttggat cgacctgaat tttttctaca tatttagcta atcgttcatc taattgaaga
     2641 cggatttccc agtttttagt tgatgctgca atattatgtt ttccgtaaac ttcaaatcca
     2701 attgtattgc cttttagtgt gtctccagtt agttcttgag gactaaattg taaatccgaa
     2761 aagttataat ttttcgtata accaggattc tcctgaaaag tattccccga agctactttg
     2821 tcacctactt gtacggagct tatcgctgtt tcaagtgggg tgcttggaga aatttcatct
     2881 tgtgcttgaa ctagttcagt tgttcccaag acaagaccaa caccaaccaa aacagatgca
     2941 accccaacac ttaatttttt gatactgtac ttcaatactc gtttctttgt tttttctaga
     3001 aatactctct tattattctt gctaaccatt attcaaatca actcccttaa tagttatttt
     3061 cttagtaaga ataaaagata aatctgatac gtattattca cagaatagga atcttactaa
     3121 acttatgtta actagtttac ttaaagaatt tcatgcacat tacaacaaaa aaagtacatt
     3181 tcttcatgtt tttttcggat atttgtgctt tttaaccatt cagcagctga aaacatataa
     3241 aaagatatgt atgtattctt tctgaaatta agttcatttc tatgcgatga agcatgtttt
     3301 caaaatatta ctctttctta gattaaactt cagagtattc aaatagcgga ataaggagcc
     3361 ttatcccgca ttactgaatg agactgtgac ataagtaaaa aggtgacttc aaattccttc
     3421 ttcggaattt gaaatcacct tctttataat tataaagtat cggtttcaca gcattcctga
     3481 atgattccta gaatcttaaa cgaatgattg gagttatcaa cattttttca ctcgttttta
     3541 gcgaaacaaa aaatgacatt tgtcacagcc tcattaaatt attgattctt tttctttata
     3601 attgaattgt ccatatttaa agtgtctagt actctacatg aataattaat tgctttcact
     3661 caaatactta taatctatta acttgtagtt gtttaacttt tctgaaaaag ttagacccac
     3721 gtaataatct tcccagcttt ctctttcaat taactgatcc aatttttgat aatccataaa
     3781 ttcatcatgt attaaaaaga ataaataact tgatatttta gcatctagct taatcagatt
     3841 aaataatgtt tgcttaaaat tgctaccatt aatatgactg atagattctc tagcttcttc
     3901 acataaactt tttactttat taattactac tttgtcatat tcatttaaca cactattatt
     3961 accattactt agacgctcag attctacgaa acaactcaaa tcagaaattt cccaaaaaat
     4021 tttttgttaa aatccaattt cctcaactcc tccaaactac gtaaatgata tagtctcata
     4081 ataaaataaa acctctcagc taatgttgtt gaaattatcc actaaaccta attgatattg
     4141 cttaggagat acacctgcgt actttttgaa tactctcgaa aagtgtgaag aatctgaaaa
     4201 tcctaaacct aaagaaactt cactgatagt atggtttgat ttcaacatta ttttagccgt
     4261 agaaattttt cgcttagaga tataattata aatcgtaata tgcatttcat tcttaaagct
     4321 ttctcttaat ttagtttcac ttacagaaaa ataattagct atttccttta cagtaattct
     4381 tttatagata tttaagccga tgaattgaac gacagaagaa attaagggag aaagatgctc
     4441 tatcttagtt tttccgattt ccttagtata ataaacaatc ccagaatccc tcacttttaa
     4501 gacctcaggt aacgatacag ctaattcgtt ttcttgtatc aaagcatctc tactttgata
     4561 cgcttctatt atatccattc ctaatgttat agacgtttgt gctaactttt caaaaacaat
     4621 gatagaataa tttttttcag accgaatcgt atctccacta acacttggaa ttattccatt
     4681 actcagatta aaaaccatgt tttctaaatt tcgaatatct ccatttttaa catattccag
     4741 tattttattt tcataaagaa acagatatat ttctggatcg taattttgtg ataacagatt
     4801 atctattttg atttgctcga tagttttact tagatttcct gtatattcaa ttaacggttc
     4861 atggaataga tcttctattt ttccagtaaa aaaataatga actaaaatca gaatatctcg
     4921 aatgtctcct aaagaataca aagtcaaatt ttgcaatgaa ttatagagtc gttctctatc
     4981 agccattgca acattcaaat tgttcatttt tagtttaaaa aaatctttat caatattatt
     5041 tgctctaaat ggaccaaata agtaatatct ggttttaaac atgtatagaa gaaacatctc
     5101 attaaaatca ccagtaaaga aatggaaatc tttagttttt ttaatattat cagttagtaa
     5161 ctttttataa tcataaaaaa ataagtagtt ctatctgagc gatactcttt tataatactg
     5221 aattcggaat taaaaaccac gataggtaac tttaaacaaa catgaagaga ctttaataag
     5281 acttctttat ctgaaaacac ttttgtttct ctctttcctt tctacatcat taaatagtat
     5341 tttatacgtt atctaaaata ctattcctct gtcaaaataa gctaacttac ttcattataa
     5401 aatatccact tatcgctttc atgtatattc caccgtaaaa agtacatttt atcaccgaga
     5461 actcatcatt tttcatcatg atgaatacta tttacatata tctagttcaa agacaataat
     5521 tattatgatc cgttattatc taagcactat acagataata ggaatttttc gtttctaaat
     5581 actcctattt gggaatccaa taaaaatttt cgttcaaata cgtgtctatt cgaactcttt
     5641 tctagttgtt aattatgaag ggggaagaaa taaaaaatac aatctataca cgaataagaa
     5701 tattatccaa aaggaggttt tagaaaagat ttattatacg taaaaagctc aagacatttt
     5761 cttagccata aggacatgtt tgatatttaa gaagatatat gaattttctt ttctaagtat
     5821 aaagataact atccattatc aactaaaaaa acatttttga aaataaacat cagcagtcct
     5881 atcaatgcat gtgagcttat agaagttatt cgcagcgcag cataattgca ttagcttctt
     5941 ttcgtgtttt ttgcctcttt tccctttaaa tcttaatgga ggaggtgtgc aatatgtcag
     6001 ataacgacga acgcgtaaat gcccagttga ttcgattctt tgaaaaggtc attttgaaca
     6061 ccgctaatac ttattataaa aaacaagaag aaattcaaaa acatgaacaa cttgatcaac
     6121 tcccaccata tttgtttact aaagatacta taaaatttaa acaaccgatt aatgttttaa
     6181 atgtgactct ccttgttgaa gatataaaat tagcaaaaat ccttcctttg ttgaaagaac
     6241 ctgaacaaat ttttcttatc gaaaaattta tctttaataa aactgataaa gaaattggaa
     6301 aggttctggg tattacaaga cagggtgcga caaatttaaa acatcgactt tacaaaaaaa
     6361 ttcaaaaaat gctggtttaa tatctgcata ataactaatt ttgtatgctt ctttgctcgt
     6421 cctcctcctt ccccaaaaaa taaatagatt ataagttcat gggaagaagg taaatttatg
     6481 aatactttaa aagaagattt cattttagca aagaatggaa atgaagaagc agttgtggcc
     6541 attctcaaaa gatttagcgc tttggtccat aagcaatcct ggagaactgg aaaatatgat
     6601 caagattgtt atcaagaatg tatgcttgca atatatctag ctatctcgaa attcgaaatt
     6661 aaagaataac tcaactaagg gagtctgtga cataagtaaa aagatagttt caaatttcga
     6721 acaataaatt tgaagccatc ttctttataa ttataaagta tcgattttac agcgttctat
     6781 aatgattcat agaatctaaa acgaatgatt ttaattatta acgtttttta attcgttttt
     6841 agcttaaaaa taacttttgt cacagtctca ctcctaaaat tactttattt acgtacgaag
     6901 tgggcaggag gtcgaatcca gaactgggcc atggtacttc aacgaggact tctcctctag
     6961 aattgaaaag catgcgattt accttccgta acgacggtag atttattcaa ctatgtgtcc
     7021 aatcaaaatt tgtctgattt caaaaatagt caagagaatt ttggttgtta aaaactctta
     7081 tctatcaact tccacagttt agttgacaaa ccctgatact aagttgggct atgatacact
     7141 tttcttgact atcagttacg ttaccggaag gaatgaactc tattgaaaaa aacatatgat
     7201 cgtaaattta aactaaagat ttcacaggat atccttgaga aaaaagtaac taccaagaaa
     7261 attgctgaag aatacaatat ctctcgtcca acaatttccc gatgggtttc agaatatcgt
     7321 cgatacggga aaaatgcttt tgctggacaa ggaaaaagat tacctgataa agcagatttc
     7381 tacattcttg aacaggaaaa taaacgacta aaagaggaag acgagtgttc tacgaacaca
     7441 aagatcgata cggatctcca gggatcactc aaaaacttta cgatgaagga atcgaaatca
     7501 ataaacgtgt tgtagctgtt cttatgcgtg aaatgaattt atgcacaaga ggatttcatc
     7561 gacgcaaatc ttctcatggt agagaaaaaa caatcaaaga aatggtaaaa aaaatgttga
     7621 atcgataatt tgaacagaac caaattgatg ctgtttgggt gacggatatt acttacattc
     7681 catgtaatga cggtcgcctc tatttgtcca cctatattga cttagcaact cgtattctac
     7741 gttactatat ggtggattca cacatgaaaa aagagattgt cgtccgtcca ttacaaattt
     7801 attaaggaga attgcctacg gtaattcatt ccgatagagg tagccagcat cggtctttta
     7861 tttatcaaga gctgttgacc gaccaccaca tcacacattc aatgagccaa actgggactc
     7921 ctgttgacaa tgcagtaatt gaagcgtttc atcgatcaat caaatgagaa ttaatcgact
     7981 ccaacaaata taaaagtaaa atagagatga aggtgttaat ccaagattat ttagaagact
     8041 actacccaaa caaaagaatc catacaaaat ttatgatgac tccttgacaa tttgaagcga
     8101 agaaa
//
LOCUS       DACBYO010000111         7826 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.111, whole genome shotgun sequence.
ACCESSION   DACBYO010000111 DACBYO010000000
VERSION     DACBYO010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.111"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(71..1492)
                     /locus_tag="IVD26_002583"
     CDS             complement(71..1492)
                     /locus_tag="IVD26_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6080499.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1735..3612)
                     /gene="tdc"
                     /locus_tag="IVD26_002584"
     CDS             complement(1735..3612)
                     /gene="tdc"
                     /locus_tag="IVD26_002584"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAP6080500.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3903..5159)
                     /locus_tag="IVD26_002585"
     CDS             complement(3903..5159)
                     /locus_tag="IVD26_002585"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAP6080501.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            5739..7040
                     /locus_tag="IVD26_002586"
     CDS             5739..7040
                     /locus_tag="IVD26_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP6080502.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7109..7708)
                     /locus_tag="IVD26_002587"
     CDS             complement(7109..7708)
                     /locus_tag="IVD26_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6080503.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT         2323 a         1597 c         1370 g         2536 t
ORIGIN      
        1 aaaaaactat tcacttggca ggacctccta ctaaatcagc gacaaaacgt cggctgaaag
       61 acttattttt ttatttttct tctaaacttt tttctacctc aatcccccaa gaatctttct
      121 tgaagtgatt gatgatcaat ggaataacga acatgaccac tgtgatagct gctactaata
      181 atgcatcact caatgtcgct gtacctaatg tagcaaatac gacaacgatg atagagaaga
      241 tcagcatgca gctgactacc caagctaatc cgtttccgtt tttaccaatt cggtaaggac
      301 gttcgaattc tggatgtttc ttacgcattt taagcaatga aacagcaatc aaaatgtaca
      361 cgatacaata aataacagtt gtagcatttg taagtgtcaa gaatacagca cttacgtcat
      421 ccattacacc ataaagcaaa gcaaataatg aaataacgat tgattgtgtt agaacgacat
      481 ttctagatac gccgtatttg ttttctttat ggaatccgaa ttttggtgga aggaatcctt
      541 cacgagctac ttggatgatt gtttttgatg gtccagtaac ccaagctgat aattgtaaaa
      601 gcacaccaat aaataccatg aagctgaaga tatttccgat cacttctggt aagcctagga
      661 tttgacagtc aatcaagata ggctgcgtga tatttgctaa ttccattttt ccatctggta
      721 cgacatttgc tacaagcatc gcattgatga cattcaataa aactaatccg atcaaagcga
      781 taaatacgcc ttttgtataa ttttttgttg cgtctttcaa acgaggcatg taaacagaac
      841 tcatttcgat cccaacaaaa ataaatgtga taccagctaa gtatttcaat gaatcaatat
      901 gttccaagtc agggaaagct tttgaccatg aaaagtcacc tagatagccg tttgagacta
      961 gtccgacttt gaaggctgcc aaaacaccta aaacgaacat gatgactact gggatatata
     1021 cccctagcca tacaccgatg ttcccgccga cttttgccat atcgaatttc aagttcaaga
     1081 tcgtgatgat ccagtagata actaaaatac aacctaaaac gaaccagtga ttattgccaa
     1141 gttctacatt accaaatgtg tttcctaaca atggtcctaa agtagaagcg accattacca
     1201 tacctgggaa catttgcacc cataatagcc atgcaacgac aaatccccat ttgctgccca
     1261 gtgctgtttt tacccataac tgaggaccgc cttcttgagg aagcatcgtg gaaagctcac
     1321 cggaaaccat tgatatcgga ccggcaaaaa acaaaactgc aaaaattgaa taaaaaatca
     1381 atgtccaacc gactgcggct aacgtaggaa tactccgaac cgttgcacac agtgccattg
     1441 tcagaccgat aaaggtccca agacccattt tacttacttc agatttactc accgttgaca
     1501 ctctccttga ttttttggat aaaataacgg tgtctttgaa gtagtttcag caataaacga
     1561 aacaattcag cgaatatttg aggggattct ttgagtttat tgcttgaagg gtttcttcaa
     1621 agacaacctc aaaacaaagg gatcgaagag cttaggtctc cccttgctct tcagatccaa
     1681 acatgcgtca gaaacagtta gtattcaagc tgttttctaa catgattacc ttgcttattt
     1741 tgcttcgctt gccaataatt ggtctgcgta gattttttcc aatttttctt gaagagctgc
     1801 tttgattttt tcagcatatt cttcaaagtg ttcttctttg ttcatgtatg gtgtcattac
     1861 gctggcacgc aatacagtta cttttccggc acggttccat tcttcatctg agaatcctag
     1921 ttggttcaca aattgtaatg ggctgttgcc atagtctggg atagcaaagt cagtatgtga
     1981 agttaagaac tcattaccgt aaatgcttcc tttcacgtat gaagaataat catatacgtc
     2041 atggttcaat ttattcattg caactaagtc atcgttgcct ttttctttga atacatagtc
     2101 taccatattg aaatctggat aagttaatgg atgaacttcg atttctttgt ctcctacttt
     2161 aaatgacaag tcattcaaga agttgtagaa acgatgtgca ccttcgattg atgcacccat
     2221 taatttacca tatcctgtga cattcaaagg taagacatgg tgtgctgccc aaacgctggc
     2281 tgctgttgcc cctgcttttg aaccttccaa gatataagcc ccaagtaatg ctgggatatc
     2341 tgcgcctttt tcaaatacat atgtcgcaaa gtaagagata acgtctctca tgcggatatc
     2401 tttgatgacg ataccaccgg cagaatatgg aacatagccc attttatgtg ggtcaatcgt
     2461 tacagattct gcttcttcga ttgctttata tgcactgtgt acttcttcta agatataatc
     2521 tttgttttct gtaaagacat tgtatttgta atgaacatct tttaaatctt caaatggaat
     2581 gaagttgttg tcttcgtcta agaaaatcgc acggccgtat ccgccataag cagcatctac
     2641 gtgtaagtag aagtaaatac cgtctttttc taatacgcga cgcaatgcaa cgattttatc
     2701 gataccgtcg attgctcctt cttctgttga tcctacaaca ccgactacac ctaggattgg
     2761 tgttttttca gctgctagac cacgaacgat tttttcaagt tcgttgatgt ccatgcgata
     2821 gttgtggtca actggcactg gaatcacttg gtctaaaccg ataccgatga tgtcggcagc
     2881 ttttagccat gaatagtgtt tagtttgtgg aaccaaccat tttcctaatt tttctaaatg
     2941 ttttccgcta cgtgctgagt gagctttgat ttcgtcgatt ttttctggga cgctgtctaa
     3001 cagattcatg atttcttctg ttgacaagtt cattaattcc caatcgcttt ttccagcaac
     3061 tagttcaggt gtcacttctt tcattgcaag cggcaatgat ttgatgttgc gggcatacca
     3121 aagtccttct aagtttgcta aagaaccatc agcaacgatg tggccccagc catctttata
     3181 gctcattaat tttgcaaatt ccattcctac ttcttcttcc atttggcttg ttgcaggaga
     3241 agattcatag gcaacgttat taccattcca tagcatagca aaattgtacg ctagtaaaga
     3301 tggcatcaat gtttcagagt tcatatgacc ccagtaacgt ccggcattat gccaaggaac
     3361 ggaatgggta cgcatccgcg ctgaaatttc tgatagaaca tcctttgttt tattcacagt
     3421 gtgttcaaaa ctagcactgc ttttttcttc tggcgtaata ataggcatgt cttgaggcat
     3481 gtagttttga cgccagccta aatgttcatc caccaattca ttcaacaaag ctttatagat
     3541 ttggccgttc tcagctttgt ccccaatgaa tagggcattt aggtttagat ctttcgacaa
     3601 tgattcactc atagtgaaac cctcctaaaa aaatatttaa attttgtcga gccctacatt
     3661 acacctgttc ttctattctg taaactaagt tttggcctga tttttaatca tattttaata
     3721 tgtatcaatt atccgaattg ttcacacttt tgaaataatt aaaaaaaacg agggaattta
     3781 caaatgtaaa ctccctcgca aagattgtat taacgacaac cagcgttcta ttttaggatg
     3841 ggtttcaaaa ttggaatgtt gtaatagtat ttcccttttt caaggtaaaa acttactaaa
     3901 ttctaatcaa ttactttggc caaaaagtaa tttttcttac cttttcgaat aaccacaaac
     3961 ttaccatcga attcatcgga tggatttatg acaaaattta aatcggtaac gcggtcaccg
     4021 ttaatactta tagctccgtt tgaaacatct tcacgtgctt gacgtttaga tggttcaatt
     4081 tttgtggaaa caagcagttc cacgatattt tcaggtgtgc ttgaaatttc aacgttcggc
     4141 attttaccga atccttgcgc gatttcttcc gcatttagtt ctttaatatt tccagagaac
     4201 aatgcttgcg ttattttttg cgcttctttc aagtcttctt cactatgcac aaatcttgta
     4261 acttcttctg ccaaacggcg ttgtgcttca cgtttctcag gttctgtctc tacttttttc
     4321 gctaagtctt cgatttcttc ttgagacaag aaagtaaaga atttcaagta tttcactaca
     4381 tcgcgatcat cttgattcaa ccagaattgg tagaactcaa atggtgaagt tttcttcgga
     4441 tcaagccaaa cggcaccgcc tgcagttttt ccgaatttcg ttccgtcagc cttcagcatc
     4501 aatgggatcg ttaaaccgaa cgcttctgct tctggtcctt ctaattttcg gattaggtct
     4561 aatccagctg tgatatttcc ccattggtct gctccaccga tttgcaattg cacatcgtat
     4621 gttttatgca gatgcaaaaa gtcgatagat tgcaggattt ggtaagtaaa ctctgtaaat
     4681 gagattccta cttccaaacg gctggcaacg atatcttttg ctaacatcgt gttgatgttg
     4741 aagtttttac cgtagtctct caaaaattca agtaaagaga tttttgacaa ccagtcgtag
     4801 ttgttcacaa atgtgatatt tgcatcttta ccaaacaatt ttctcatttg attggaaagt
     4861 gcgtccacgt tatgttgcac ttgttccatc gtttgcaaca cacgttctgt tttgcggccg
     4921 cttgggtcgc cgatcgttcc tgttccgccg ccaatcagaa tatatggatg atggcctgcc
     4981 aattggaatc ttttcatcat cataaatgga atcaaatgtc cgatatgcat cgaatcacca
     5041 gttggatcaa cgccgcaata aagtgaaatg ctcttttctt caacgagctc gcgaagtctt
     5101 tcttcgtttg tttgctgatt aatggcgtcg cgccaagtta attcatcaat aatattcatt
     5161 ttactgacct ccgtgtagtt tttttatgaa agcaggaacc tgctagcatg tgtaattaat
     5221 tatttcttca ggataggata ggaaataaaa aaagtccctt ggcatataag ccaagggacg
     5281 aaatctcgcg gtaccaccca atttgtatgt ctagatatcc aacatacctc tcgaacattt
     5341 aacgctgtcg cgtggcaatc actgccaaag actcctgaaa tgtaattcgc tttaaagcat
     5401 gtactggttt gcagcgacca ccagctttct gaaacattgg ctttaacaac tacttcgttt
     5461 cgatcttcgt cttgttatta ttaatatgtg tctatcatag agcgcaactt tttctttgtc
     5521 aacagaaaaa ggatattttt tttaaattcc tcattttttc ttttttgaat ccgctctaat
     5581 tccgaacatt ttattttcaa ttattgttaa aagaaataac tttttctgta ttttttctgc
     5641 aatttatcga gaagtcactt tactttgcct cttattcttt cttcgttaca ataaggaatg
     5701 ggacaagtaa aaaaatgaaa aagcaaggga cgaggtatat ggaaaaaaag caaaaaatta
     5761 ttttaggagc cacttctgct ttaactatcg ttattttaat tctaagtttg ttttttgtca
     5821 tccgatcatc tacaaaaaaa gaaccaatca ttcctgaaaa aaaaataaca gaaaaagcaa
     5881 aagaaccgac agatgataag caacaactag ttactcaagc aaaaaatctg gctcaaagct
     5941 acgattatga ccaagcgatt gcgttattgg aaaaagatag taagaacgga tctactgaaa
     6001 cacaacagct tcttcaaaca ctaaaaaagg agaaagaaca actgatcgac tggtctgatc
     6061 ctactcagat ctctcatgtc tttttccaca gcttgatcgt ggacccgcaa aaagccttcc
     6121 actctcaaca ggcacaagga tacaaagatt atatggtgac tgttgaagaa ttcaaccgtt
     6181 cgatcgaaca actttatcaa aatgattttg ttttagttaa tttgaatgat ttgatccaaa
     6241 aagacgaaca aggaaatctt tcctttaacg ggcttgcgct acctgaagga aaaaaaccat
     6301 tggttctttc acaagatgat gtcagctatt atgaatatat ggataattcc ggttttccta
     6361 gccgattggt cgtatcaaat aacaatgaaa tcaaaaatgt ctataaagag aaagataaag
     6421 aagaaatcgg tgactttgac atggttcctc tgatcgatgc ctttgtcaag aaacatcctg
     6481 atttttctta tcgaggcgca aaaggtacct tggccctgac aggttacaac ggagttttag
     6541 gttatcgaac atcaaaatct caatatggag acaatgaaaa aacaaaaaaa gagattaaag
     6601 aagctaaaaa agtggcggaa cagttgaaga aagacggctg gagctttgct tcccatacat
     6661 ggggtcactt gaatatgact caagcttcac tagaagatgt aaaaaaagac aatgaattgt
     6721 ggcagcaaga agttgcacct atcctaggaa aaacaaatat tctgatttat ccatttggtg
     6781 cagacatcag cgactggcag ccttattcag cagaaaatca aaaatttgct tacttgaaga
     6841 gtcaaggttt cgatattttc tgtaatgtcg atgcttctac accagcttgg ggacaattag
     6901 gtacggattt ctatcgaaat gctcggatca atatcgatgg cattcgtttt caatctgatt
     6961 tagacggaaa aaatcctatt cttgatccat tcatcaatgt ccatgatgtc tatgacaaag
     7021 aagcacgcga atctgcttga ttttacgtca tttatgaacc aaaaaagccg aactgacatt
     7081 ttatcgtcag tttcggcttt tttatgcttt atttcttctt cggtgcgatt cccttgatca
     7141 ggacttctgt ccattctgct gtatatggaa gcagttttgc gtatatctcc ggcttagaaa
     7201 ttccttctac cattgcttga aaatagagga tcaagaactc atccgaatat ttcaaatcca
     7261 cttttccttc tttccgccct cgatggaaaa gatcaagcat gatactgaaa ctttcttgcg
     7321 tatacgcatc catcgcgtca gaaaattctt ttttttcttt ttttgtatag tatgtcatca
     7381 aatcgatata aaattgtttg ttcactcgat tgagataacg gattttgttt tcactcatgg
     7441 caatcagtgt ttcttcaaat ggaagatttt ccgcaatcaa cgctttcgct tcttgcccta
     7501 aatcattcat aaatgcaaaa aatacttcat aaatcagccc ttccttgctg ccaaaatatt
     7561 taaaaatcgt cgctttactt acctgagcgt tctcagctac cttatccatt gtcactccag
     7621 cggttcctat gtctgtgttc atcaagtcaa aagctgcttg taaaatctct ttctttttct
     7681 cttgtgctct cttttcaaaa ccgttcattt gtagagcctc ccgtaatttt aaacttttat
     7741 aatatatata gttcaaattt attctgaggt ttattataac tatctattga gaaagtatca
     7801 agctagcaat tccttgttta tgaatt
//
LOCUS       DACBYO010000112         7691 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.112, whole genome shotgun sequence.
ACCESSION   DACBYO010000112 DACBYO010000000
VERSION     DACBYO010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.112"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..2242
                     /locus_tag="IVD26_002588"
     CDS             <1..2242
                     /locus_tag="IVD26_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP6080504.1"
                     /translation="KYLHPIMISIILIFTFLGSLSSIYVNVYTETSNFANQTTEETNS
                     PPYSEIQSIESTNQSSNNETTSTTSSTQLIDPTEKEITAAKAAGEKAYSETGRSQTFS
                     TVAATANFNGHTIPDGYTVIYAKDGVIVAVNGSMSADKTALQGVTKAIAFIDNRPDIH
                     NLFIGSTVNGTTITFPKSIYMGVATAGNTIDSVTPNADKSYSFTPSTWGGLPAGGGMS
                     TFSIGIQLANDIPFTGYSIKNGQIVDGKGNVSNFPTYQAATVQVNANRTGTFSYTVNG
                     GAAKIGTYGTTLSGIHVGDKVVITPTAVTGYSFAQTNGSFTALESNVDTVTYTGKQTP
                     ITIKYQDYFGQMIAPSKIMNLTYGSAAQDLTTNTPTINGYTFTAVSATETKNQSAMSV
                     LASLDTNGNVIVKDANGKQISEVILYYKTNATVSINANGSKYYDGLSVVPIVKYAFND
                     KTESTSLLNNDLSIDQITWNPTDFKAMNEKGVEVTAPTEIGTYTSWQLTKSGLAKLAA
                     RTNYLFTIVQTSDVYTIKQISGAVELSGSKTYDGKAGVPSIHVKLAEGVTSSLTPVQV
                     ALSSMDYTADAQSAKNMVNAGSYTIKLTNSGIDKVKAANPKLSFTDIANTSGTYTIYK
                     ANAVITVDDAAFNYDAQSHSISVGNLHVTGVVLGESLDYTLTVNSRTDIGSQIVTISL
                     GEGSVNNNYTIIATDTAKLTINPTLLLPSTGGIGLLPFVFLGLIFIFSGFFYFIHRKK
                     KAGEQR"
     gene            2368..2697
                     /locus_tag="IVD26_002589"
     CDS             2368..2697
                     /locus_tag="IVD26_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAP6080505.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            2737..3741
                     /locus_tag="IVD26_002590"
     CDS             2737..3741
                     /locus_tag="IVD26_002590"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP6080506.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            3738..5167
                     /locus_tag="IVD26_002591"
                     /pseudo
     CDS             3738..5167
                     /locus_tag="IVD26_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            5373..6545
                     /locus_tag="IVD26_002592"
     CDS             5373..6545
                     /locus_tag="IVD26_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP6080507.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(6707..7162)
                     /locus_tag="IVD26_002593"
     CDS             complement(6707..7162)
                     /locus_tag="IVD26_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080508.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
BASE COUNT         2600 a         1441 c         1527 g         2123 t
ORIGIN      
        1 aaaatactta catcccatta tgatttcgat catcttgatt tttactttct tagggagctt
       61 atcaagtatt tatgtaaacg tttatacaga aacgtcaaat tttgctaacc aaacgacaga
      121 ggagacaaat agtccaccct attctgaaat acagtccata gaaagcacca atcagtctag
      181 caacaacgag acaacctcaa ccacatcctc gactcaactg attgatccga cagaaaaaga
      241 aatcacagca gcaaaagcag caggggagaa agcttattca gaaacaggta gaagccagac
      301 atttagtact gttgcggcca ctgcgaattt caacggacat accataccag atggatatac
      361 agtgatatat gccaaagatg gagtcattgt tgcggttaac ggatcgatga gtgcggataa
      421 aactgcgtta caaggcgtaa ccaaagcaat cgcttttatt gataaccgtc cagatatcca
      481 taatctgttt attggctcca cagtaaatgg tactactatc acattcccaa aaagtatcta
      541 tatgggggtg gctaccgctg gaaatacgat cgattcagtt acacccaatg cggataaaag
      601 ttattctttt acaccctcaa catggggagg gcttcctgcc ggaggaggta tgagtacttt
      661 ttcaatcggt atacagttag caaatgatat tccattcacg gggtactcga tcaaaaatgg
      721 gcagatcgtt gatggtaagg gaaatgtttc aaattttcca acctatcaag cagcaacggt
      781 tcaggtcaat gcgaatcgga caggaacttt ttcttataca gtcaatggtg gagcagcaaa
      841 aatcggaacg tacgggacta cattatctgg aatccatgtg ggtgacaaag tggttatcac
      901 tccaacagca gtaacgggct attcttttgc acaaacaaac ggttctttca cagccctaga
      961 aagtaacgtc gatacggtga cctatacagg caaacaaaca ccaatcacta ttaagtatca
     1021 agactatttt ggacagatga ttgctccttc taaaataatg aatcttactt acggaagtgc
     1081 tgcacaagac ctgacgacta atacgcctac tatcaacgga tataccttta cagctgtttc
     1141 agcgacagaa acaaagaacc aatcagcaat gagtgtttta gctagtttag atacaaatgg
     1201 aaatgtaatc gtaaaggacg caaatggaaa acagatttct gaagtcatcc tatattataa
     1261 gacaaatgca acagtatcaa tcaatgcaaa tggcagtaag tactatgatg gtctttctgt
     1321 tgtaccgatc gttaaatatg cctttaatga taaaacagaa tcaacatccc ttttaaacaa
     1381 tgatctcagt attgatcaaa tcacatggaa tccaactgat ttcaaagcga tgaatgaaaa
     1441 gggagttgaa gtaactgcgc ctactgaaat tggaacctat acgtcttggc aattgacaaa
     1501 aagcggacta gctaaactag ctgccagaac aaactattta tttactatcg tgcagacatc
     1561 tgatgtctat acgattaagc aaatcagcgg tgcggtagag ctcagtggca gtaagacata
     1621 tgatggaaaa gcaggtgtcc cgtcaatcca tgtcaagcta gcagagggtg tcactagttc
     1681 gcttactcca gtacaagtgg cacttagcag tatggattac acagcagatg cacaatcagc
     1741 aaaaaatatg gttaatgctg gcagctatac aattaaacta acgaatagcg gaatagacaa
     1801 agtcaaagca gcaaatccca agttgtcatt tactgatata gccaacacat caggaactta
     1861 taccatctat aaagctaacg cagtgattac tgtcgatgac gctgccttta attatgatgc
     1921 ccaaagtcac tcgatttcgg ttggaaatct ccacgttacc ggtgttgtct taggcgaatc
     1981 attggattat accctaacag ttaacagccg gacagatatt ggatcacaaa tagtaacgat
     2041 tagtttaggc gaaggaagtg taaacaataa ttatacgatt atcgcaacag ataccgctaa
     2101 gttgacgatc aatccgactc tcttgcttcc ttcgacaggt gggataggtc tactgccctt
     2161 tgtcttttta ggactgatct ttattttttc tggcttcttt tattttatcc atcgtaagaa
     2221 aaaagcaggt gaacagcgat gaaaaaaaca aaaaatgtac gtgtggatat atttgctgtt
     2281 ctctttttta tcctactggt cttttttata ggttctccga ctgtgtcagc tagagaatca
     2341 cctattacat ttactttgca taatcgaatg ttcgaaagcg ataagatgcc aagtatcagt
     2401 caaaacgacg gaataaatat cccggataac tttcaaggag taaaagggtt gaacggcgtt
     2461 actttcgcta tatatgatgt ctcggatgaa ttttacaagc tgcggtcaga aggaagtagt
     2521 gtggaagacg cacaaagaaa actagcacaa aaaagtgata gtgaaaaaat actggcagaa
     2581 aatgtgacaa aaacagtaga cgaggaagag ggcattgctt cttttagtgc atcggacaaa
     2641 gatgagcaag gtcgtgacgc tgtttaccga tttgcggaaa taaagacttc agattaagta
     2701 aaagaaaaat cagcaccatt tgtcgttgtg cttcctgtga cagattcatc taatcataaa
     2761 ttgacgacca tccacttgta tccaaagagc gaacaaaaaa tacctgctgc actcacatta
     2821 acaaaaacag tagagaataa gcagacagat tttgcagatg gggataaagt tccttatctc
     2881 atcaccgtaa caattcctga gaacatcaac gagataggaa cctatacgat caaagataca
     2941 gctgatcctc agttatggct agaaccagaa acgatcgatt ttttgattgg tggagacaag
     3001 attcatacat ttcacacaca aaaaacaaaa catggttttg tcttatcaga ttctggaaaa
     3061 gatcttagtt cgtttgctgg gaaaaaatta acgatccgtt accaaatgac attgaaagaa
     3121 aacagtgaaa aaacgacatt tgataacgat gtacgtttga cgactgacaa tcaaacagta
     3181 gaaacacatc ttgccatcca aacaggaggc aaacaatttg tcaaagtgga tcggcaaacg
     3241 aaacaaaaac tagcagatgc tcaatttcta gtcaaaaaaa atgaccaata cttagcgcaa
     3301 gaaaacggga taaatcattg ggtagccaaa gatgattcaa gagcaacgat ttttacttcc
     3361 agtaaagatg gaacattttc tgtccatgga ttgtcttttg gaagttacga actagtggag
     3421 attaaaccgc ctaaaggata tatattgagt caatcaacca ttctctttga agttgaaaaa
     3481 ggcagttatg atccgcttca tcctatacca ttggaaatca tcaacgaacc aaaagcaaat
     3541 ccgacgaata atggaaaaac gccagttcag atgcagacaa atggtccatc aaatgaaaaa
     3601 aatggaggaa gctttccaaa aacaagcgaa gagatgcttg gaggtttctc aattttaggg
     3661 ttgttgctag tcctttcaac agggacagct tggttttata aaaaacaaca aaaaggaaac
     3721 aataggaggg aaataaaatg aaaaacatca aaacaaaaat atggacgttt ttaggaactg
     3781 ctatcatgct gcttcctttc gttctcggcc taggaactgc agaggtttct aggccgtatc
     3841 acctacacca gaaaatgtta cggttaattt gcataaattg aaattcactt cagcaccaga
     3901 aaatcaaata aacaacggaa cggaattgac atttccgaat agcgaaccgt tgaacggcgt
     3961 tgaattcaac gtatatgaca tcactgctac gtactatcca agtaaagaca cagcagttcc
     4021 agcagacgct acacccttcg caagtgtaac gacttctggt gaaggattag ctaacctgac
     4081 tcttccaggt aaatctgatg ggaaagatgc tgtatacgtc tttgtagaaa caccaaagcc
     4141 cggtgtcgaa acgtcgccaa atatcgtgtt aagcttaccc ttttataacc cgaattcatc
     4201 agaccctgac aaacctttag acacgattca cctatatgct aaaaatgtca tcaaagaaag
     4261 caatatcaaa atccagaaag ctgggaactt ttcaggggta gataagttag caggggcgca
     4321 attccagatc aaaaattcag agaatcaatt cgtgaccggt tttgatgaaa acactggtgt
     4381 cgctctctat gatcctgctg agtcagcgtt gacattcaca actgatactg aaggatccat
     4441 cagtgtcaat ggattaatag acggcaatta tactttagtt gaaacaaaag caccagatgg
     4501 ttatcaatta accaatccac aaaaagaaac tacttttata gtaaaaaacg gaaaattgca
     4561 acaaacaacc ggtatcatcc atggcgcaga tgaagccaat cttgggaatc caaacggtgt
     4621 agtcaatcgg gaaaatacaa ctacggataa cacgattact gtagaaaatg tccaaaacta
     4681 cggtgatttc cacttcatca aacaagatgt gaacacgcaa gaaaaattag ccgatgcaga
     4741 attttctatt ctaagagcaa aagatccaac tgttaaatta atgaaaaaaa tagcaaatct
     4801 tgcctcagga gaatacccat atgcttggtc agatgaagtc acaggttctg actgggaaga
     4861 agtgaaattg atttctgatt cagaagggaa attttcaatc gaagggctga aacaaggggc
     4921 atactgcctt caagaaacaa aagcaccaga aggctacgca ttacctaaga atgaagctgc
     4981 gtacactgaa tttacagtag atgatgatcc aacaacttct gatgaaacaa cgatcgataa
     5041 ccaacctaaa ggaatcttgc cttcaactgg tggtatgggg atcatcgtat tcatcttggt
     5101 aggtactgct ttagttggag gagcagtgat ctacttcaaa aaacgccatc aagaaacaga
     5161 agcttaaact attggaaaca aaaatcatac gataaataaa cgatagtgat tcaaatgggg
     5221 agaaaggttg tgacaagtgg tcggtctctt ggtattcgct caacaaacgg caaaatagga
     5281 ggaactattt tgccgtttgt tgagcgaata ctcaggtcaa ggcgctgatt tcacaacctc
     5341 ttcatataca tattagaaaa taggtggaca tgatgaataa aagcagaata agaatactgg
     5401 acatcttcat ggcaatcatt ttagtcgttg ggatcgggat cttttcttat ccttttgtag
     5461 aagattcact gaatgatttt cttgcccagc aaatgatcat ccattatcaa aagcaagcat
     5521 cgaataagaa ttcagaggaa ataaaaaaac agcaggaaaa aatgacaaag aaaaaccaac
     5581 agttggcaga gcaaaacgta tcaccaggga taggcagttt caaccaagca gttgatgcaa
     5641 aagcattaaa agatttacct agtaatgcct tttttatgga acatatgctt ggagtcatcg
     5701 aaatcccaaa aatcaatgtc agcttaccta tattcgatca gacaacggaa atatttttgc
     5761 aaaaaggaac gtcattattg gaagaaagtt cttatccgac tggcgggaaa aacacccatg
     5821 ccgttctttc tgggcatcgt ggactcccag aagcaaaatt atttacagat ttgcctaagt
     5881 tgaaaaaagg agaccagttt ttcatccaga tcaatggaaa gacattggcg tatcaagtag
     5941 aaaaaatcca agtggtctta cctgatgaag tagattcttt gggtatccaa aaaggcagag
     6001 atctcgtgac tttgcttacc tgtactcctt atatggtcaa tacacatcga ctgcttgtga
     6061 cggggcatcg tattccttat caagcaaaag aggcaaaaaa agcgatccaa ggaattgatc
     6121 aatggaaaaa atggaaattt tttatttggt ttatcggtat actacttgga tcaatcggct
     6181 tagtttggct actcatcgct tatttagatt ctttggccat cgctaagcga aactatcctt
     6241 tatcttttta tgtaaagaac acaaacggac gaccaatcga aggaatggtc ttttctgtaa
     6301 aaacgctcaa cggcaaacac tatattacta gagaaaaagt tccatttgtg aaagcttctg
     6361 atgaatacgg actagtgaga ttttctgatt taaaaggcag gaactatcgc ttgcaacatg
     6421 aggagctcct gcttaaaatc catgtaaaac ataaacattc gaaacagttt tcaatgaaat
     6481 tgaaaaaagg aagatataaa ctgcgaaaag aaaaagaggt gtactatttg attgagaaag
     6541 aatgaatgaa gatgtccaaa aaagcagagg gaacagacta aatgaaaaaa gagagaagct
     6601 gacgaaatgg acgtgtaaac tgctattttt ggtttactat ctggaacgcc agcttctatt
     6661 tttttatgtt tcagaagaat tttattatta tagtataact tttgaattag tttccataac
     6721 atttggagca aggggttaaa ccacgagctt gagcttcgct taaagtggca ggggtatacg
     6781 taccatttcc acatttatgt gtatggtatt ttgaaccggt cggtgtgaca tagacagttt
     6841 gttcattatt ttgctcagga gctgcggctt gtgcctgctg agaggcctgt tcagctgctg
     6901 cttgctgtcg cgcctgttct gcttgttgct gtgcgattgc ttcttgttgc gcttgttctg
     6961 cttgttgtcg tgcaatttct tcttgctttt tccgttcttc ttctgcttct tttgctttga
     7021 ttgtggaatc aattgcagca agacggcttg tcaactcttg tttgttttca ggtagcgctt
     7081 ggatagctgc tgaagcagtt gcatagtttt cttttgtagg atttgcttca gcttgtgaca
     7141 aagcagattc cgcttctgtc actttttttt ctagtgcagc tttttccgct ttttgtttct
     7201 cttcttcttt tttcttttca atttgttctt gttctttcga tgaatctgcc gtactttcgg
     7261 agatcgtggt actgctgctg gaagcctgag ctgaacttgt gctttgagta gtagacgtag
     7321 tagcaccaca cccactcaac aaacttcctg cgaccaaaaa caatgcaact aattttttca
     7381 ctaaatttcc tccttaagta aaaaacaacc gttttcaata aatgtccttt tcaattgttt
     7441 acttacttgt tataataatt gtgttatgaa tagtgattga ggaaacttaa tctaatcccg
     7501 ttttgataca cgggattttt tgctatagtt ctgttattaa gtatgcaata ataaaatatg
     7561 tacgttattt tattattaga ttattgacat ttatataata aacgattaaa tgattcatat
     7621 caatagaata cttaggaaaa aaagagaaat aataacaggt ttatgcacta ttgacggtgt
     7681 gacaatatga t
//
LOCUS       DACBYO010000113         7670 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.113, whole genome shotgun sequence.
ACCESSION   DACBYO010000113 DACBYO010000000
VERSION     DACBYO010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.113"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..813
                     /locus_tag="IVD26_002594"
     CDS             <1..813
                     /locus_tag="IVD26_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAP6080509.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSLTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKIARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="IVD26_002595"
     CDS             807..1229
                     /locus_tag="IVD26_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080510.1"
                     /translation="MVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2363..3331
                     /locus_tag="IVD26_002596"
     CDS             2363..3331
                     /locus_tag="IVD26_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP6080511.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     NFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELL
                     QQLAELERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
     gene            3341..3829
                     /locus_tag="IVD26_002597"
     CDS             3341..3829
                     /locus_tag="IVD26_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP6080512.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKE
                     AVTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQ
                     QKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQF
                     WQ"
     gene            4125..4406
                     /locus_tag="IVD26_002598"
     CDS             4125..4406
                     /locus_tag="IVD26_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080513.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            4408..4824
                     /locus_tag="IVD26_002599"
     CDS             4408..4824
                     /locus_tag="IVD26_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080514.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
     gene            complement(5579..6727)
                     /gene="tnpB"
                     /locus_tag="IVD26_002600"
     CDS             complement(5579..6727)
                     /gene="tnpB"
                     /locus_tag="IVD26_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAP6080515.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(6744..7148)
                     /locus_tag="IVD26_002601"
     CDS             complement(6744..7148)
                     /locus_tag="IVD26_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HAP6080516.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     gene            7329..>7670
                     /locus_tag="IVD26_002602"
     CDS             7329..>7670
                     /locus_tag="IVD26_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAP6080517.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYVYTV"
BASE COUNT         2710 a         1327 c         1246 g         2387 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcccttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tttctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgcgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaaatagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaact cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctcgaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaagc
     1441 cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca aacgatacgt
     1501 cctatggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat ttggctagca
     1561 atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt cgagtgagcg
     1621 aatccaaatt tgcaactctg aagctttgca aatgagtgtg ccggcttccg taaaagtcta
     1681 ggtaacatta gtcgatatat acatagggct ctaatttgcg ttttaaggcg ttttaaacgt
     1741 tctggtatgt aattatacca aagcgacttt aaaacgcctt aaaacgaatt ttagaggttc
     1801 tgtagaacgt tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg ctttaaaaac
     1861 aagataaggg attttatcta gacttgtctt aaaacgccgt agatgagcgc tcagagcttc
     1921 taaaaggact ccttacgaac tgtttttaag caaaggagcc tttaggcgac tgcgcagttt
     1981 aatgtgagag cgtagcgatc acacctttaa agcgaccgta gggagcagat tcccagttta
     2041 ggaaatttcg cgaacctgtt tggagaaaaa aagtaggaaa attttaggcg ggaaattttg
     2101 cccccctctt ttataatctc ttttataacc tctttttaaa cctctttacc gtcggctgta
     2161 tccttactct cccaaggtgt gcagaatctt ttaggggtct ttttgtctgt ttttaggggt
     2221 ctttttgtct gtttttaggg gtctttttgt ctgtttttag gggtcttttt gtctgttttt
     2281 aggggtcttt aattaggggg ttgaccccca ttagaaagct ctttataatt ttgttaagta
     2341 gttaatcttg aaggaggatt ttatggcaaa tgaaattgtg aaataccacc atgaattaaa
     2401 tacgattcct ttacgcaaat ttacgtcagt agaaatgaat ttattcttct ctataatatc
     2461 tagaatgcgt gatgtaggcg ataaaaaagt acaatttaca ttcgaacaat taaaagattt
     2521 aagcaattat aaagcaactg caaatgttcg attcatagat gatttagaaa caacgtatga
     2581 caaattaatg gatttacgtt ttggtagaag aagtgctgac ggtttgcaac gtgaacgatt
     2641 tgttttattt aatcaattta aaatcgatgg aaaagctgat attccttttg ctgaaataca
     2701 agtccatgag aaagccttac ccttacttaa taatcttgaa gaatgggttc gatattctct
     2761 ccaacaattc aatgaattag aaagcagtta ttccaaaacc atgtttagat tattaaaaca
     2821 atacagaacc aaaggaattg ccaatttttc aaaagaagac tttcatgaat tacttgatat
     2881 ccctaaaagt tatagagaaa gtgatataaa taaaaaaatt ataaagccta ttcgccaaga
     2941 actaaccgca atcttcaaag gtttgacaat ccaaaagaga tacggaaaag gacggggaaa
     3001 gcctgtcatt ggctatcaat ttacatttaa acctgagata aaaaaatcag acgactttaa
     3061 caaacatgct ccaaccaaag aagaacaaaa taaagctttg gaactagcta atcaacaggt
     3121 tcaatctgaa aaagaaccta cttcattaca agaaaaaatc aaagaacaaa aacgaaaatt
     3181 agaactttta caacagttag cagaattaga aagaaaacaa aataccccaa gtaagaaaat
     3241 taacaaacaa atagcagata acaattccga tattacccca gaatttaaag aaaacttact
     3301 agataatctc caaaacttat ttaaagaata aggggttttt atgacagata aaactatcaa
     3361 agaattagca gatattctag gtgtttcaaa agataaagtg aagtatcaac tgaggaaatt
     3421 acctagtaat tttacctaca aaaaaggaaa tattacctac ctgaaaaaag aagcagtaac
     3481 aacaattaca aaggttttat caggtaatga atcgggtaac ttacctagtg aattacccga
     3541 ttcattacct accgattacc tactcaagga gattgaaact aagaataatc atattgaaga
     3601 aaaagatagg caaattgaaa aacttcaaat agctttagaa acgcagcaaa aattactcga
     3661 ccagcaacaa caactcaccc tacaagccaa tcaacaaatc aaaaaacttc acgaacaact
     3721 ccagctaacc tatgcagaag aatcttcaga aaaagaaccc ctttctgtta ctgaagaaac
     3781 tcaaaaagga caaaacaagg agaaaaaatg gtggcaattc tggcaataac ccaacaattt
     3841 ttattcataa aaattgttgg gttactttct ttttttgctt ttacaagcat agcgacatga
     3901 tctcacgtcg ctatttttta aagagcataa ggaaacgcgg tatcactttc ttacgaaagg
     3961 tgctaggtag gctgtgccta ccacgtttct aagaaaaaaa tttgctatca ctttttcgtc
     4021 attgtggata gcttatgtat agtgtttcgg caaaaaacag ctatacaaat actatatttg
     4081 tatgatatac ataaattata cacaaatgcg aaaggaattc ttctatggac attttagttc
     4141 ggaatattga tccaaaagtt atttcagaaa tagatagacg ttgccaagaa ctcacaacaa
     4201 aaactggcaa aaaatggagc cgtaatgcgt acctaaaagt tctaatcgaa aacgattttg
     4261 accaggcact taggcattac aaaaaagatc aattcgattt attactcgaa aaatttatcg
     4321 atatacaagc aaaaaatact gaaacattga acgactatgt tcatacaaac aaccaactca
     4381 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgttacc
     4441 ctttatccca gtcacattga cgttttagat tccatcatcg aaaaaaatcc agatatcaat
     4501 aactactcgg aagccattcg ttttctatgt atgagttatg aacctaatac taatacgaca
     4561 actaccagca accaagcaaa actaaatgcg atgggaaaag aaatttctat tatgtccgaa
     4621 atcattgcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4681 tctaaagtat atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ctcccgacga
     4741 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacat tcacttctag aaattttgac
     4801 ccaacaaact ttctaaaaag atgaaaaaga aaccgaaaat tttttctatt tctcagtttc
     4861 ttttttaggg ggcagtcttc cagcaagatt tgcaagttac cggtaacttg cacaaaaaaa
     4921 gaaaaatccg cttgtgcgaa tccttctttt tgcattttgg ggcgctgccc caatctccaa
     4981 atatcggtta tttaatagcg tggtaactca aaaaaataga acgtactctg aaataaaaaa
     5041 agactgctct tccgagcagc caataaaaaa taatgagcgt ttattcttga aaaagcaacg
     5101 cgcttatgaa gcgctgccaa aaatttacca tattttatga aaaataacaa gtttctaaaa
     5161 aggaatcggt taagattcac aaagaatcgt aaacagacaa tagcggaaaa tcaagcttcc
     5221 gaacgtacct tttagctaga ccaatgaaaa atcacaaagt gagcccctgt atcggttgat
     5281 acaagggcta cttggcatac tcgacattat gtctactagc tcgataaata acgattatgt
     5341 tcccaaaaca atattttatg aactataaca aaaatttgtt atcgcatatt gtatatttta
     5401 attataggtg tatatcacgt gaactactca ccacttagct aaacctgacg gttcttaacg
     5461 cttgaagtgg gagcttcttg ggaatagagc atacttgata gcgtatttct ttactaacag
     5521 cggtgtctct tatttaccaa gctatccccg tagttcctac ggttcttgat gattggatct
     5581 aagccaatcc catagaatgt agtcttagac cttcggtcag aatattgata ctagcattga
     5641 tatcacgatc atgatgagta tgacaaacag gacaagtcca ttctcgaatt tcaagagatt
     5701 tcttgccatc tttatgtccg cactctgaac aaatctgact agacggaaac catttatcta
     5761 ctttgatgat ttttcgtcca taccagtcag ccttgtattg taatttagtc acaaactttg
     5821 accaagaaac atcagaaata cttttagcta atttatgatt tcgcaacata ccttttgtgt
     5881 ttaagtcttc aatacagata atatcgtgat ttttgatcat ttctgtactc aacttattca
     5941 gaaaatcagt acgttgattc attacttttt catgcaatct agctactttg cgtttttgtt
     6001 tttgataatt tttagcttca aatagattgg tacctttatt tttagccaat aaagcacgcc
     6061 tagacaattt gcgttgttca cgctttagtt tcttttccat tttggacgtg aatttattat
     6121 tatcaatttt ttgtccatca gaaagaatcg caaagtccat aatacctaag tcaataccaa
     6181 ttgtggaatt agttttaggt aattcgataa tttcttcttt acacaacaaa gaaatatagt
     6241 atttaccgct agaatgacgt gatattgtag cagatttgat aatccctttt ggttgtctat
     6301 gaagcttaat tcttactaat gacttcaatt taggaacttt gatgaattta ctatcaatca
     6361 aagcaactgt accattttga ttattcgttg tataactctg aacaggattt ttcttacttt
     6421 tgaaacgtgg aaatccaacg gatttatccc gaaaaaaatt cttgtatgct ttatctaaat
     6481 taagttgggc attggctaaa gcaaggctat caatttcttt caaaaacgga aattctttct
     6541 tgtatttagc tggtgtcgga aaagtcattt ttttagaaga atcattttta acttcttcat
     6601 acgccttttt tcggtcatca agcattagat tgtagacctt acggacacaa ccaaaagatt
     6661 tggcaaagaa gatttcttgt tcctctgttg gatagattct gaatttgtat gcttttagtt
     6721 gttccataaa gttcacctac tttctattta tgattgtttc cttgattttg gatatacttc
     6781 ttaatcacat caattggtgc gccaccagtt gtcagaagac aaaaactttt agaccagaac
     6841 atttctttcc aaagaaattg tttgactctt ggaaagtcac gttttatcaa tcttgagctg
     6901 gcacttttat aggcattgat gaattttgtc aattctgttt taggttgagc tttgaacata
     6961 atatgaacgt ggtctttatc atgattccac tccactaaag taatgtgata cgattctgaa
     7021 attctttcaa aagtagtttt ggcataatca gatatttcat catcaatcac ttgtctacga
     7081 tatttcgtta ctaaaacaag gtggtaataa agaagaaata ctgaatgatt atttgtatct
     7141 aattccatgt tatatcaact catttcttgt atagactgat tgtaacatgg aacaaaataa
     7201 aaaggcaata cgccttagtt gtcggtcttc gagttaccaa cggtaaccct cataccgaac
     7261 ggcattcatc acccacctat agaggatggg cgacttctgc ctaattctgt taaatttaac
     7321 acaaaggcgt gattattttg aaacccaaaa agaaaattta tctaggtctc ctcttttcct
     7381 tgatgattgg aatttttagt ataggaatta caaataccta tgcttcagaa aattctaatt
     7441 tcaatatcaa ctcccaacca attgaagaac aagcaattaa ttttgcgaaa actgattttg
     7501 aacactccat aacttcaatt cttttaatgg aaaataacac cgaaactgat attaactata
     7561 ctcttggttc gccatttaaa atgctcgatg gagaaaatac ggcaaatagt tctattttct
     7621 ttccagtatt ttcagacgct gataatacga ttaaatatgt ttataccgtc
//
LOCUS       DACBYO010000114         7627 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.114, whole genome shotgun sequence.
ACCESSION   DACBYO010000114 DACBYO010000000
VERSION     DACBYO010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.114"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(16..708)
                     /locus_tag="IVD26_002603"
     CDS             complement(16..708)
                     /locus_tag="IVD26_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP6080518.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            793..969
                     /locus_tag="IVD26_002604"
                     /pseudo
     CDS             793..969
                     /locus_tag="IVD26_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1145..1714)
                     /locus_tag="IVD26_002605"
     CDS             complement(1145..1714)
                     /locus_tag="IVD26_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP6080519.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1788..2111)
                     /locus_tag="IVD26_002606"
     CDS             complement(1788..2111)
                     /locus_tag="IVD26_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080520.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2265..3077)
                     /locus_tag="IVD26_002607"
     CDS             complement(2265..3077)
                     /locus_tag="IVD26_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080521.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3431..4279
                     /locus_tag="IVD26_002608"
     CDS             3431..4279
                     /locus_tag="IVD26_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAP6080522.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4424..5365
                     /locus_tag="IVD26_002609"
     CDS             4424..5365
                     /locus_tag="IVD26_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAP6080523.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5355..7526
                     /locus_tag="IVD26_002610"
                     /pseudo
     CDS             5355..7526
                     /locus_tag="IVD26_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2273 a         1512 c         1372 g         2470 t
ORIGIN      
        1 agaggggggg attttttatc gttgtggaat atttaaatac caacgcttgt catgaaaatc
       61 ttgtgctcca cccttagtat ttccttctgg atcgtttgtc gcacgcatca tgacgtatac
      121 tttcttatta gggaaatcac gcatattgaa agatacatga tagccaacat ttcctaaagt
      181 attataagct tgatttacgt ctggtctata aatcccatca gctcttactc tagctagttc
      241 ttttccagta ttgtagtcca taatgaaaat atactcgtat ttataattag caatgtgcca
      301 tccagctaca tgcaagtttg cgttttcgat ttctccgaac tgatcaatgt gggcgtaatt
      361 tgttccatct gtcagcgtag aatttgcagc acctgctcga gttggatcaa ttactggttt
      421 atcctccgaa gtagttggat tatcatccgt aaaaccatga gccaaatcat aggctagttt
      481 ttctttactt acacctattt cagaaagata accgtaagga tctgtatgat cgccccaaat
      541 attttgtgtt acccataaat gcgatttgat tcctggttgg ttataaggag tgtctaatgt
      601 taatggaata ccatatttca ttgctgaatc tcttgccaat tcaacgtata ctttatagtt
      661 cttttcaaaa gtttctttat catgtgtgtg ttgtaactcg atttgcacag gacttttggc
      721 tcacgaggtt gtcctactct acatcttgct gatagatatg ctgaaaggaa aacaccaaca
      781 ttatgttttg ctttttcagc tagaacgaga caagcaggaa tacctttaga agatatcaaa
      841 ggttttttag gtcataaaga tgtttccact acacaagtct atgcccatat ttctcccgaa
      901 gtgaaaaaaa gatcaatgaa tcaactagaa aactatatag aagagcaaat aaaaaagcac
      961 tcaaattgag tgctttttta agctcactat cactaaaact atcactaatt ttatttataa
     1021 gcgaacatgt ttctatcact gattttttaa atctagcgaa aaacccttat cttaaaggcg
     1081 ttcgttcaat tctttggcaa ggtcttcaaa gcctggcttg cctagaagtg cgaacatggt
     1141 tttcttatag ctcatgtaga aaaattttct tgatgatgat tttatccatc aattgagatt
     1201 gactgttttg ctctcctatg atttcagcta tgattgtccg attttgcggt tttcttctta
     1261 actggtagtt gattttccca gtttccatca actcgctaag catatccacg actccgccaa
     1321 atccggtctt tttcgtaata aaacctagtg ctaccattcg ttcatctaga ttttttgctg
     1381 taatcgtcac accagtaatg agcgagtgct gtaatgtttg ggccagctct tccatccctt
     1441 cagcattgga tacgacggaa gctgttttgt taataggttc ttcgtttatt tcttttggtt
     1501 ctttcctctc cactttcact gtttgacgaa ggacatctag ttcttgcaag agcgtttcgt
     1561 attgttcttg ggtcagcatc acgccagcta ctttttcacg attaaatata tatacgccag
     1621 ttcccgcgtc tcgcgcttga gcaaatacat ccatcggcga tcgtttcact tctgtgatcg
     1681 aagatgtggg aacttctaat ttctttaatt ccaatggatt tcctccttta ctaatcgctt
     1741 tttattatag cacagactga cttgttttga tcttttttcc aaaggtttta tcggtttttg
     1801 cctaaccagt aattgatatc ggtaagaagt ctttcgatac caaatgaagg atggtacaga
     1861 tacgtttttt gatcttcgtt atggtctagt ggaaaaaaat gatcgatgat cactagatct
     1921 gcataccgag gcggcttatt tcgagtacat acatgtatag agatccgttt tcgatgtctt
     1981 agcgttttgt tcagtacccc agcaagtctt cttgcttctt ggtgttcata gcgaaaaaaa
     2041 aagacgattt tcacttcagg agggtggaca tctaaatacc ctcgttcctg gagtgttttc
     2101 agtaaaagca tcccccactc tactgcgggg tgtgcaagtg cttgttggat cgctagccga
     2161 aattgatata gtttatcttt ggaattggga aatttttcta atgtttcctg ataataacga
     2221 acttcttcta tcagccggtc atggatacca attacgtaac gaagtcattc ttggtaaagt
     2281 acttttgtca gctttgattt gctttcgctc tcaaattcgc tattcagcca aaacagcgaa
     2341 tcaagctttt cagtcacaat cgtcaatttc cgatagtctt gtgtctcttc tatccgtttc
     2401 caccgctttt cagtaatctg gttacagctc aagcgcaaaa ttgctagata atttttttct
     2461 tttattggca aaatctgctc ctctctaaat agcaattcag gaaacaattc aaagaatagt
     2521 gttcgactgt ctcctaaaat ctcgatttct gccggatcct ttctttgctt caataattgg
     2581 atgaacatct cagaaaagga ctgctctcca tcatctgcaa aaaaatgcgg aaaatctttc
     2641 aaaaagcaaa acagcagata tcttactttt ctttctgaac caaagatctg tgctttttta
     2701 taagaaaaag aaaggtggta ctcgccaaac cactttctca atcgctcttg cgtagaacga
     2761 tcgtacttct gctcgtaagg ttcattcaat agcagatttt tcagtaaaca aaacgggggt
     2821 gattggatca gaaaaacaaa caagagataa ggttcgctat atccttgatc ataaactaac
     2881 tgaacggttt tcttatgaag aatcagctga atgggacagt cgctttccgc caaacgtttc
     2941 agatgccgat ccactgtttt aacatcgatt ttcagttctt cagctaaatc agcttttcgc
     3001 cagatcaaat ctttcattag attgattagt gaaaataaat tctgtgcatt ttttgataat
     3061 agtttttgcc atctcatcga tcatttctca cctgatttct aaacatattg tttgatcaaa
     3121 atgggttcac tcctaaaaag ataaaaaact ccctttctat ttatttaaat acgcaaatct
     3181 tcctcattat tttttatttt actcaattta atcgtattct catttcaaaa cgaatgtact
     3241 ttaaaaaaac ataataagat cactttgctt gtaggatgta ttcccttcca ttacaatgaa
     3301 ataaatagcg attttatgag aaggtgatgt gaaaatggaa gaaaaaatag aagaatccaa
     3361 acaaaaaatc gatcagttga tataagaatt agaaaaagcg gtcatcggca aacgttcaac
     3421 tatccaattg atgatcgtgg ccctattagc aggtggtcat gtcttattcg aagatattcc
     3481 cggtgtaggt aaaacgttac tggtcaaagc actagcaaaa gctgtacagg gaaccttcag
     3541 cagagtccaa tgtactcctg atctgctgcc tagtgatatt cttggttttt ccgtatacaa
     3601 ttcacaatca aaagagtttg aatttcgtcc gggaccgatc tttaccacga tcttgttagc
     3661 agatgagatc aatcgtacga ctcctcgtac tcagtcagca cttttagaag caatggccga
     3721 gaatcatgca acgatcgaca acaatacata ccctctagac aatcattttt ttgtcttagc
     3781 tacgcaaaat ccaatcgagt acgaaggaac atatcctttg ccggaagcac agctcgatcg
     3841 ttttttattc cgactacaaa tcggttatcc ttcttttgat gacgaacttt tgctactttt
     3901 ggataaattc gaaaaagtgt tggataactt aaatgaagta ttgaacagtt atgaaataga
     3961 agaaataaaa acaaatgtgg cgaatgtctt tgtcagtccc gaagtggcat cttatgcctt
     4021 gcagttagtg tcagcaacaa gaagtcatgc tgccatccag cttggcatca gtccacgagg
     4081 aagcctttcc tttattcagg cagcaaaagc ttatgcttta atccatggga gaaattacgt
     4141 cacgcccaaa gatttgcagg atttagttcc ttacgtgttt tcccatcgcc tgatttttta
     4201 cgatcgttca ttgaaggaag acgaaaagaa acaaatcatt catactcttg ttgcacaaat
     4261 tcctattcct gtgaggtaga ttgaggtaga caatggaaaa aatcaaagat tatttcatta
     4321 attttgtgtt atttctggta tatttcatca ttgtgctttt tgctcttgta ttcaacaatt
     4381 ctttaggctg gttcttgttg gcctttttta ctctttatgt atcatggagc ttgatttcat
     4441 taagcagctt tctaaagaaa ctttcggtta cttgtacatt gcagccactc gtttatcgca
     4501 aaaaaagtat gcaggttatt ttttccatag caaaaaagag aactttttct ttacctctcc
     4561 ctcgtttaca aatcggcttc ccagcaatct ttgcagaaaa aaacaagaga ttttgattct
     4621 tacaaataaa ccgcaagaag tccaattgct ttggcagcca aaagaaagag gatgccatga
     4681 aacattaact gtcattttta cagcctatga tagtctagga cttttcagaa aaagtgcaaa
     4741 aagagagatc tcttttcctg tgactgttct gcctgctttt tgtaagattc aagcagaaaa
     4801 attacagaga gttctggaaa aaaaacagca gctgaacgcg taccaaagag gtcttgattt
     4861 tcgggaacat cgcgcttatc gtccaggtga ttctttcaac cgaatcgatt ggaaattgtc
     4921 tgctcatact caagagtggt tataccgtga atacgattat caagaagaag aatgttctcc
     4981 tcttttttgc ttttggggtt cgcccagtcc aaaatttgaa cctctgctag acttgtattt
     5041 ttctttatgg catttgagaa aagaaaagca gccggaactt ctgatattag gcaaccgcgc
     5101 ctttcatggc aaagaccccg gtcataccta ttttgcttct ttggaagctg gcgatgagaa
     5161 aacttttttc gcacacttga aaaaatatgc aaaaaaacaa atcgtcctct ttgttcctga
     5221 gaattctcct gaagtctcag aagctattga aacattgtca aaagatcgaa cggtttatct
     5281 tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa gacaagatat gttcattgcc
     5341 aggaggtgaa tggattgacg attaaacggg aaaaatggct gcgtggcgtt tactcctttg
     5401 tgatactaag tgtaggtgct ccgatatttg tagtagctaa tcaattgcaa aacagctacc
     5461 ttcttatcct aactattggt gtcctatgcc ttattgtctg ctgtattcct aaaaaatggg
     5521 tacgtttgct gctttctttg ccagtaatga taggttgttt gtttttatat tttccttcga
     5581 agacattttc catattatgg atcttacagt ttttttcgtc agttacagag gaattcttcc
     5641 atctatccca aggtaaactt tattatttgc cagaaaagac agcttttttt ctcataatgt
     5701 tgctgatcta tttatttatt acattgaccg tggattacga ctattggtac gcaccctttc
     5761 tttctttgat ggcttacttc atgatgctta ccgtttttcg gaaaaaagat ttactgtacg
     5821 aaatgattgc ggtagtaact gttttgttcg tgtatctggc agcaaggcaa tttttctcca
     5881 tccggttgtt gtcgagaaac actcgattcc agtcattgac tacagttctg cttatttgtt
     5941 tcttaacttt tagcgctatc ttgcctttat atcttccgaa agtacaccaa tctctcgagg
     6001 aaacgagtga accgatccga gaatatctta atgatgaagg gctttatgac acactccatg
     6061 agtatcaatt aaccggaagt gcaagaacag gcttcagtga gaatgatgaa cagcttggtg
     6121 gacctttata tgataatggc gaagttgttt ttacagcgaa ccaaaaagga aatggctatt
     6181 ggaagatcga aaataaaaat cattacaccg gttctggatg aatagaagat caggacgcac
     6241 ccatccaacc aatccaagaa ttccctgttg acatcacgag ctaccaaacc gttatagaag
     6301 acaaagaaaa cattacattg accctaaaaa aacaagcttt cttaccttat ccttatggaa
     6361 atactacctt gactgatttt tcattagcta gtggacaaac gctttactat ttgcctgaaa
     6421 gccagcgatt cattcctgtc ccgaatgaat cgacacgttc tgcaacttta caaacagaaa
     6481 ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt aaaagctgat gatttagaaa
     6541 atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa acgtattgag gacttggcgg
     6601 tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt cgaagctgtc taacagtatt
     6661 taaaaacaag cggaaatttc cgctattcca aaacggatac cgggcatact ccaaaagaac
     6721 acgattatgt ggattatttc ctctttgatt caaaagtcgg ctattgtgac aacttttcaa
     6781 cttctatggt cgtccttctt cgaacacttg gtatcccagc tcgctggaca aaaggtttta
     6841 caaatgggct cagaacaggc acagataatc aagggaatga ggaatacagc attctcaata
     6901 gtcatgctca ttcttggcca gaggtatact ttcctggatt tggctggctt ccatttgaac
     6961 caaccccttc atttgccaat ccaatgggtt cacaaccagt tgctgaaaca accgaaaccg
     7021 tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat ggcagaaact atttccagtg
     7081 agagatctga ggtcattcca tcagaagaaa caacactcac accagcttat aaaatcgtct
     7141 tattcagcct tggagtgtgt ttatccgtct tgttgttctt tctattgtta ttcagaaaat
     7201 ctctgcgctg gacaagttat cttatctatc ttcatttttt tgcttctact aatacgattg
     7261 catatcaaaa acttcttaac cctttggaaa cattggtacc gcgcaaaccc gcagaatctt
     7321 tgcaggaata tagcctgcga atagaacaag aattcaagct agatctgcgt ttcattcgat
     7381 taactactca atatgaagca gaaatatatg gacgacaagc agatccggta aaattcgata
     7441 aaaaaaccta tttagaaata acgcatataa taagaaaaac ggtatacaaa aaaattctga
     7501 caaaagggag ccgcttcaaa aaataagata aaatttctgg agaatctact tctcgaatgc
     7561 cgagaaccag ctgattgagt atcgattact cgaaaaaaag gttgtgacac gttttttgtc
     7621 acaacct
//
LOCUS       DACBYO010000115         7604 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.115, whole genome shotgun sequence.
ACCESSION   DACBYO010000115 DACBYO010000000
VERSION     DACBYO010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.115"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(15..1013)
                     /locus_tag="IVD26_002611"
     CDS             complement(15..1013)
                     /locus_tag="IVD26_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAP6080524.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1088..1384)
                     /locus_tag="IVD26_002612"
     CDS             complement(1088..1384)
                     /locus_tag="IVD26_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080525.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1377..1670)
                     /locus_tag="IVD26_002613"
     CDS             complement(1377..1670)
                     /locus_tag="IVD26_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080526.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1816..2367)
                     /locus_tag="IVD26_002614"
     CDS             complement(1816..2367)
                     /locus_tag="IVD26_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HAP6080527.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEEKEKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFSRGNDEQSLE
                     ILTTIFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2541..2840)
                     /locus_tag="IVD26_002615"
     CDS             complement(2541..2840)
                     /locus_tag="IVD26_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HAP6080528.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGTLPKNVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVCGLLVEGRLVWSQIGGTNE"
     gene            complement(2867..3175)
                     /locus_tag="IVD26_002616"
     CDS             complement(2867..3175)
                     /locus_tag="IVD26_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAP6080529.1"
                     /translation="MFQNKGQRYVTKGVMDSLLVELQTLCWNLIDQNVQKKLPLDYLQ
                     IFEFSIEKGNQKLVHRQEEPEARKEYLISPKLRLESVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            3505..4647
                     /locus_tag="IVD26_002617"
     CDS             3505..4647
                     /locus_tag="IVD26_002617"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080530.1"
                     /translation="MKALTISFMEDVFHSLDLEHLNKLAKVLPQKLSGSSIIPKNPSD
                     SFKNRLFNQFLKEKNLRYIFKYISSGYFHDIVANDENIYKSTSIQSIEGFFEEIKNKE
                     LESPFSFYIYLIEQTDEDNIVDFFQNIDGLRTFKNNSLIYIQNKKKNKGCTDISLEYK
                     KMEDLLTLYKKDKIDAENREKVLLKENERLKKKIEKNNNDKIRELSKLEKKFLAEKEC
                     EINRYKEEITNSLLKLKNSESKYLNLEKKFSILNSTLKNKENEIVELKKRCNSLINTS
                     KTVKTISHQTKESIKKILLIGVPGKIVIREDYNFIITNPDTPLEDIIKIIEENDINEL
                     WITTFQLIPRMKKKIIQSLKNKIKIQELNDFTMLMKEENINGFKTR"
     gene            5618..6622
                     /locus_tag="IVD26_002618"
     CDS             5618..6622
                     /locus_tag="IVD26_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP6080531.1"
                     /translation="MLGDSLVVLAGLSGTGKSQLVTSYAKALQLSDTQIKFISVRPFW
                     EDDSDLLGYADTVNSVYRPGDSGLIDALLEASRHKENIYMVCFDEMNLARVEHYFSQF
                     LSVLEMEPNTRKIKLYNEDLENKLYNSSTYPSTIEVGQNILFVGTINTDESTHQFSDK
                     VLDRSNIISLELVPFHEISEVNDYIQSDQKKRNQLKYDDFKNFKNSNPTNGLTQKEKE
                     MFWKLHLAINSKDKNIGIGWRILKQIDEYLKNLPVQNDLSRKEAIDIQLVQRVLSKIR
                     GSDEQLSELVGKWNENDLKQVGEFEQIINEYPESSDFKYTKKILLQKARELNLHGFTL
                     "
     gene            6606..7397
                     /locus_tag="IVD26_002619"
                     /pseudo
     CDS             6606..7397
                     /locus_tag="IVD26_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290077.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2739 a         1192 c         1085 g         2588 t
ORIGIN      
        1 aataatattt tcaattattt aatcatttga aaattgttag tcattccaat acgttgagaa
       61 attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt gtttccatca
      121 tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat tagatctttc
      181 atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg agaatcatac
      241 aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact tgaaattcct
      301 gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc ttctactact
      361 ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa ctgttgattt
      421 tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg cgttaaataa
      481 actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa atattctcca
      541 gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt tccatcttct
      601 gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc attaatcacg
      661 gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta gcttttatat
      721 tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga agctttattc
      781 gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga acttgcactt
      841 gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt tttacttttt
      901 ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt ctcagatgta
      961 caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt cattatattt
     1021 ccccctttca atttctccct cacgtactta ttctatcaga caattaattg atctaaatgg
     1081 taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag cggtctcttc
     1141 cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat cctctacagc
     1201 gataagttct cattattttt gggctattag tattattttt cttagttaga gctatgagtc
     1261 caactatgat taccccaact gtcttaatta cttttccttt atctatattc ggatgcgcaa
     1321 gcatatattg atataaccaa tatccaccgt aaattaaacc acctaataca atcagcttag
     1381 ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct tgcagagaaa
     1441 ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat catgttttcg
     1501 attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat ctgttgccct
     1561 cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc ctcaaaaaag
     1621 tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat ctacacaccc
     1681 cctgttattt tttacataat gaaaatagca tattactggg tacattgata attcatataa
     1741 catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt ataagtaaca
     1801 tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca attgccattc
     1861 attacgaaca tgaatactta atgggtgaga taacttgcct tctgcattta tcaatacttt
     1921 ggtcatcttc ttttgtttcg cactcaattg atcgtaaatg gtctttgctt gttcataagc
     1981 cacttgactc gttgccgtaa tcgaaccaca agcaaaaata atagtgttga ttttcttttc
     2041 tgtaaaaatg gtcgttaata tttccaaaga ttgttcatca ttgccacgag aaaatacccg
     2101 aggacttttc gcttttgtat acgaaaaaag attcacggca ataaaaccag taaatcccaa
     2161 ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg gttctgtatc
     2221 tgttggacga atggtaatga ctactgctaa tttttctttc tcttcttttc ctttgattgc
     2281 ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa cttctgtttg
     2341 tgtggtcact aattcttttt caatcatctc tttttctcct atgctaattt ttgttcaagc
     2401 aattcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt catattcttt
     2461 ctcctttttt cttcagaatt cgataaatcg cggtaaggat atcttctaaa catttcgcaa
     2521 tcattctcaa ataatcgatc ttattcattc gttcctccaa tctgactcca aaccaatcgt
     2581 ccttctacca gtaacccaca aacaaattct cgctggctgg taatatctgt aatgaaataa
     2641 actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt catcactaaa
     2701 cgtggtagat gaacattttt aggaagcgta cccatttcaa tttcctcttt ttccatcgta
     2761 acggattcat agccccactc ttcaggagta gtgactagct gtgcacactt ttccagtact
     2821 tcgatagccg tttctaacaa gtcatttcgc tcctttcttt tagatatcag tattcttctg
     2881 gtaataacat cgtttgatac tcacccgaat caatgaccca tattttttga gacactgatt
     2941 ccaaacgaag cttaggtgaa atcagatact cttttcttgc ttccggttct tcttgacgat
     3001 gaaccaactt ttgatttcct ttttctatcg aaaattcaaa gatttgaaga tagtctaaag
     3061 gaagcttctt ttgaacgttt tgatcgatta gattccaaca taaagtttgt aattccacca
     3121 gtaaactgtc cattactccc tttgtgacat aacgttgtcc tttattttga aacatttctt
     3181 ttccctcctt tgtcgtaaaa aatagcccaa tcttctataa agaagattgg acttcatgga
     3241 tataatatat atttgaattt atctctattt cattgctata ttatttattt caattaactg
     3301 aatagacatc acaactaaat ataagaaatg cttttctaaa agtatggagt tttcatattt
     3361 agtacctcta tactaaattg cgactacaag tttaaaattt atatagttat tagtaactaa
     3421 gatacttaat tttgcttaat gaactatcct attaatgtta tactactatt gttattataa
     3481 ataatacaag aaaggaagtc aaaattgaaa gctttaacta taagttttat ggaagatgtt
     3541 tttcattctc ttgatttgga acatcttaat aaattagcga aagtacttcc acagaagtta
     3601 agtggctcat ctattattcc taaaaaccca tctgattctt ttaaaaacag gttatttaac
     3661 caatttctta aagaaaaaaa tttaagatat atatttaaat atattagtag tgggtacttc
     3721 cacgatatcg tcgcaaacga tgaaaatatt tataaaagta cttctattca gagcatagaa
     3781 ggattttttg aggaaattaa aaataaagag ttggaatccc ccttttcatt ttatatctat
     3841 ttgattgaac aaacagatga agacaacatt gtagattttt ttcaaaatat tgatgggtta
     3901 agaacattta agaataattc tttgatatat atacaaaata aaaaaaagaa taagggttgc
     3961 actgatatct cacttgaata taaaaagatg gaagatttat taacccttta taaaaaagac
     4021 aaaattgatg ctgaaaatag ggaaaaagta ttgctaaaag aaaatgaaag actcaagaaa
     4081 aaaatagaaa aaaataataa cgataaaata agagaactca gcaaactaga aaaaaaattc
     4141 ctcgctgaaa aggaatgtga aataaatcga tataaagaag aaataactaa tagtttatta
     4201 aaattaaaaa attcagaaag taagtatctt aatttagaaa aaaaattctc tattttaaat
     4261 agcacgctta aaaataaaga aaatgaaatc gttgaactga aaaaaagatg taatagtctt
     4321 ataaatacaa gcaaaacagt aaaaactatt tcacaccaaa caaaagaaag tataaaaaag
     4381 attttattaa ttggtgttcc aggaaaaatt gttattagag aagactataa ttttataatc
     4441 actaatcctg atacacctct cgaagatatc attaaaataa ttgaagaaaa tgatattaat
     4501 gaattatgga ttacaacctt tcaattaatt cccagaatga aaaaaaagat tatacaaagt
     4561 ttaaaaaata aaataaaaat tcaagaatta aatgatttta ctatgcttat gaaggaggaa
     4621 aatataaatg gttttaaaac aaggtaaaca agattaccaa attattggtt atttggagga
     4681 tgatttaaat aaaattaaaa taaactcgga tgatgtaatg tactttttta tgactcctct
     4741 ttcagatttc cccagtagtg tgattgataa tgtagagggt atacaaatat atagtaatac
     4801 gcttactaaa tttgggttta ttgatgatat aaacgaatct catagtactc gtgcccaatc
     4861 acttaaagaa tttttagatc cttatattat cgtttgtaca ccaaaaatta aaagaaatca
     4921 tgaacaagca agaaattact atcaaggtga tgatttagaa ttaatcccca aaccaaagtc
     4981 tgaagttttt aaaaatttaa taaaagagaa tgaatcatta gtacctatac cggtcttttc
     5041 tataaataac agcgattctg taatcaaaga cgagacaagt tttgaaaacc aattactaaa
     5101 cggcaaacta ctcggaaaaa ttataaattt ctcaaaagac aatgaagatt accctttaaa
     5161 tgttttttgg gagaacactg atggatcaag agttttattt ggtgaaataa tcggacaaaa
     5221 caattcaatg tacggtgtag catataggat agaaaaagat aatttttaca aaaagtttat
     5281 tgatgaaggt agtaaaaact atgtaggtta cgatgatttt ataaatcaaa caaaagatat
     5341 aatttttgtg ccctatctat tacttcaaaa aattatagaa actaaaaaag atattaacga
     5401 aggcatagaa aatatctctg attccaaaat atctccagta agttcaatta ttactgaaca
     5461 aacgcaaata gatatatctg agttagaaga taaacacgct attcaacaaa atgatcactt
     5521 ctctgaacat aatgaattta tagaaagatt taatcagctc acaattcgta gtaaattaca
     5581 ttactcaaaa cgagacttat ggaattttca tactgctatg ttgggtgata gtttggtggt
     5641 attagctgga ctaagtggta ccggtaaatc acaattagta acatcctatg caaaagcact
     5701 tcaattatca gatacacaaa taaagtttat ttctgtgaga cccttttggg aggatgattc
     5761 tgatttattg ggctatgctg atactgtaaa ttctgtctat cgtccaggag atagcggtct
     5821 aattgatgca ctattagaag catcaagaca taaagaaaat atttatatgg tttgttttga
     5881 tgagatgaat ttagctcggg ttgaacatta tttctcccaa tttctttcag ttttagaaat
     5941 ggagccaaat actaggaaaa tcaaactgta taacgaagat ctagaaaata aattatataa
     6001 ctcttcaacc tatccttcta caattgaagt aggacaaaac atattatttg taggaacaat
     6061 aaatacagat gaatctactc atcaattctc agataaagtt ttggatagat caaacattat
     6121 ttcacttgag ttagtaccat tccatgaaat tagtgaagta aatgactata ttcaatcaga
     6181 tcaaaagaaa cgtaatcaac ttaaatatga tgatttcaaa aattttaaaa actctaaccc
     6241 tactaatggt ttgacccaga aagaaaaaga aatgttttgg aaactccatt tagcaattaa
     6301 ttctaaagac aaaaatatcg gtatcggttg gagaatatta aaacaaattg atgaatattt
     6361 aaaaaatctt ccagtgcaaa atgacttatc aagaaaagaa gctattgata ttcagcttgt
     6421 acagagagta ttaagtaaaa tcagaggttc tgatgaacaa ttatcagaat tagttggtaa
     6481 atggaatgag aatgatttaa aacaagtggg tgaatttgaa caaataatta atgaatatcc
     6541 tgagtcttca gattttaaat atactaaaaa aattcttttg caaaaagcta gggagttgaa
     6601 tttacatgga tttacccttt agtctgaaat taaactttgg ttataaaagt gaagaacaag
     6661 aatatgaact tttatttttt caagatgagg catcgttatt agagtataca ccggttaagg
     6721 taaaagaatt ttctaatcta agctttacat ttaacagtat agacaaacac gcaaaactat
     6781 atataccaga attagatgat tatttgattg aaaatcaagt aaaagaggaa aatggagata
     6841 tttgctatat tccaagtgat gataatataa tcatttataa tagggatcaa ggtaaaacag
     6901 tacctcttat tccaggttat tacactcttt acgttaaaat aggtgaaact atcttttatt
     6961 ctcgatttga aataatactt aaagatttag gtacaccaga atgggaaaaa atgaaaatcg
     7021 aaattgaaaa aatggttggc ggtcttgcta gaacttttat tcctaaaaaa acttctcgtc
     7081 gtgaaattac tacttcaaat tatctaatga acgatcaact ttttcaacga atattagagt
     7141 ttgagaacaa tatacctcaa gcaatagttt ctcttgaaag tttaaaaaaa gaagcaaaat
     7201 atagaattga caaacgatat aactggaaac caattggaag caaaaattta gtggatcaaa
     7261 aaactatttc acagttgcaa atccatccag aaaaacgtgg gctactatat acacctagcc
     7321 gcataataaa atatgatatt attgaaaatc aatggatcaa atttatctta tcttatttta
     7381 aaaatttttc acttctagct gatagatatt tagagaaaat cctacaaggt attattgaag
     7441 agaaaaaaag agaagataag tttactagcg cgtattctca aagtgtacaa aactacaata
     7501 caaatagcta taatagaaag attgaaaatt tgaaaaacaa tcagcaaaag ataaaacatt
     7561 tttatgctta tatccttgaa tttttagaca caccagtaat gaaa
//
LOCUS       DACBYO010000116         7537 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.116, whole genome shotgun sequence.
ACCESSION   DACBYO010000116 DACBYO010000000
VERSION     DACBYO010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.116"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            107..1248
                     /locus_tag="IVD26_002620"
     CDS             join(107..335,335..1248)
                     /locus_tag="IVD26_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP6080532.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            1483..1935
                     /locus_tag="IVD26_002621"
     CDS             1483..1935
                     /locus_tag="IVD26_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080533.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            1949..2638
                     /locus_tag="IVD26_002622"
     CDS             1949..2638
                     /locus_tag="IVD26_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080534.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            2763..5114
                     /locus_tag="IVD26_002623"
     CDS             2763..5114
                     /locus_tag="IVD26_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAP6080535.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            5194..5589
                     /locus_tag="IVD26_002624"
     CDS             5194..5589
                     /locus_tag="IVD26_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080536.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            5914..6531
                     /locus_tag="IVD26_002625"
     CDS             5914..6531
                     /locus_tag="IVD26_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6080537.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            6572..6871
                     /locus_tag="IVD26_002626"
     CDS             6572..6871
                     /locus_tag="IVD26_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080538.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            6905..7072
                     /locus_tag="IVD26_002627"
     CDS             6905..7072
                     /locus_tag="IVD26_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6080539.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(7117..>7537)
                     /locus_tag="IVD26_002628"
     CDS             complement(7117..>7537)
                     /locus_tag="IVD26_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6080540.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2594 a         1138 c         1502 g         2303 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc gtagaatcta actactaaga aaaggacgtg tccacgatgg caaaagccaa
      121 gaaaaaattt gatgaagact ttaagaagat gatcttagat ttaaaccagt ctggccaatc
      181 ggtcgaagaa ctggcagcgc aatatggtat cgctacacaa acgatttatc gttggaagaa
      241 gcttcataca aagaatgtag caaccggcat gactgaggca gaaatcctag cgatgaaaaa
      301 ggaaatggcc cgcatgcagg aggaaaacac tatcctaaaa aaggctttaa ccatattcgc
      361 tcaaaagtaa aaatgagtga tgtcttcgaa tttattcaat caaatgttca tgatcatgac
      421 gtaaaacaaa tgtgtaccgt tttggaagca ccgaaatcca gctactatga ctggaagaaa
      481 aagaaacctt ccaagcgcca atcagaaaac aaacgcttaa accgcttgat ttcaggaatc
      541 tactttgaaa acaagggtat ctatggtgcg cctaaaattc ataagattct tgttggccgt
      601 ggcgagacct tgtccttaaa gaaagtacaa atactgatga gaaaattagg cttgcgttca
      661 gtcaccctca agaagtacaa gcctggcaaa caagcgaaag ttaaaagtga aggacgtaaa
      721 aacctgttaa accaagattt taccactacg tcgatcaatc aaaaatgggt gacagatatt
      781 acctatattc ataccctaaa agatggctgg acctacctct ccactattca agacctccac
      841 acaaagaaag tcatcggttg gaagtttggc aagcagatga cgaaagaatt ggttatcgaa
      901 acccttgaca atgcgctctt aaaccaaaca ccctccgaga acttgatcat ccactcagat
      961 ttgggttctc agtacactag cgaagcctat gaggcaaagc tgaatgaatt gaacattcgg
     1021 cactccttca gtcgtaaggg ctgtccctac gataatgccg gtatcgaatc gtttcacgcc
     1081 tcactcaaaa aagaagaagt ctatccatca aaagcgtatg aaaactttga agctgcttat
     1141 ttagcgttat ttcaatacat tgaaggattt tacaatcgca agcgaatcca tagtagtatc
     1201 aactatttaa caccaaatca gatggaggag ttggcattgc aagcttagtt cctagctacc
     1261 acttacattt ttttggcgag atttccacag ggtttcaact tcatcgcttc gatcagcggt
     1321 caaacggttt tggtttgacc gctggtcgaa acgatgagat actcacccgc tggaatctcg
     1381 aaaaaattct cacaaatcgt gtccgaggta ttgactcaaa tccaccaatt atcttatcgt
     1441 agatatatat tataaattta ataagaaagc gaggtgagaa tcgtgaaaaa aacgatacta
     1501 agtatttttt cagtatttac aatattaatt gggggctatt ttcttttgaa tttagattct
     1561 gttaattcaa acgctcaaat aaaagatcaa agagtagctg aacataataa taaaaaaatg
     1621 agtttgacca aaaatatcta ttctatgtca gatgaagaat tgtataaaga atttggtgat
     1681 ttatccgggg aacagttaga agaaagtatt ccaggaatta gtgactcaga taaaattgtt
     1741 gtcttgtctg ctggtgggca attaatggga gatggcaaat ccgaattagt tagttataaa
     1801 caaaatcaca gacagtttat tgatgttaat actgattcca acgctatttc gattaaggat
     1861 ctaaaagagc ttttaaatag taaaagaaat gaattaaagc agataaaaga aactaattca
     1921 gtggaattag agtaaaggaa gattcattat gaaaaagatt tttggtgttt ctgttgggct
     1981 acttatgatg ttaacatttg gaaatgcagt atatgctgct gagaaagaag ttatttcaga
     2041 tccagagcag tacgcctcac gatactttgc tgattttgaa gaagaagata aagtacttgc
     2101 attgccagaa ggtggttttt taaaagggga agctaaaatt gtatctatgg ataatccaga
     2161 tataattcaa ggttcatata attcagaaac tgatcctgct tcagtttcag tgacagaagc
     2221 aaaaaaaatt gttgctgaaa aattcaaaaa tgatattgaa actactccaa ttatgcctcg
     2281 aggagcattt ccacccgatg ttggtactag cggacacctt cttgtactag caggaggagg
     2341 aagctataaa tcacagccat ttagtggtgc gggatggcgt tttggaggta tgggtgtaaa
     2401 accagctgat ggtacaggca actttttacg ttggaaatcc tacattgacg atggaagagt
     2461 aggaaatgta aatcaagcca acgcaactaa atctggttct attcaaggaa tggcattgta
     2521 tgctcgtgaa ggattcaaat actttgcacc aaacgggcct ggttggacaa tgaatatagg
     2581 tatttattac acttataatc ctgttgcagg tacgtattat gttgttcaaa atatttaata
     2641 aaacagcaca aagagatttc tttgtgctgt tttattattt ttagttgttg acaaacacta
     2701 aaatataaaa tataatcaac acataaacga acgtatgttc ggcaagaaag caggggattt
     2761 ttatggatga gatggtttta agtactcaga aatggctaaa caagaaatac agtaatgtta
     2821 cagggtttga taaggttcca gaaaatgggc gaacagggtg gcctacaatc tatggactta
     2881 ttgaaggact acaagtagaa cttggtatta ctaatctagt agctaatttt ggacctacca
     2941 ctgaaaaaat gtacgataat caggttactc ctaaatgggg caaaaatcta cctaaaaata
     3001 ttgtatttct tattcaaggt gccttttggt gtaaggggat taatccaggt ggcttcgatg
     3061 gggtatatac tccatattta gatactgctg taaaagagtt gcagactgat gcagggttta
     3121 atggaagcgc tgtaactgga gttttggatg cgaaatgggc caaagcgtta tttgatatga
     3181 gtgcttttgt tcttgttccc ggcggagata gtaaaattag aaaaatgcag caatggttaa
     3241 atgtaaatta tttagaatac acgggaataa tgccttgtga tggtatttat caaagaaatt
     3301 caaatcaagc attaattttt gcattacaag ctgaactagg atattctccc agtgaagcaa
     3361 cagggtctta tggtaatggg acaactagta aaacttatcc tgtgtctgaa ggtaactcgg
     3421 gaaactatgt aagaataatt caatatggat tatatgttaa tggttatttt gaagacggta
     3481 cattcgatgg tattttcact aaatatatgg gtttagaagt actggcattc cgaaaattta
     3541 tggtattgcc tgaatatact gaaatagcag atgttgttgt aataaaagga ctattgtcta
     3601 gcgctggaga tattagaaga tctgcagatg gcgcagatac ttctacgcaa ttaactagat
     3661 ctcaaatcca aacattggtt gataatgata taaaaatagt tggtagatat cttactggta
     3721 ctgttggaat tggaaaagat gaacgaaata agtatctaac tacagaggaa ttgaataata
     3781 ttttttctaa aaatttatct gtgtttccta tctatcaaga tggaggtgca gcattagctt
     3841 attttactta tgatcgtggc ttatcagatg gtaagaaggc tatagatgca gcaaaaaatc
     3901 taaatatacc attaacaaca gttatttatt ttgctgttga tctagacatg ttaggggaag
     3961 aaattcttgc atatgctgga gaatatttta agggggtatc tgctgtaatg tcatatagcg
     4021 ggtatcaaac gggtgtttac ggaacaagaa atgtttgttc tcaaataatc aataacgggt
     4081 atgcttcgtt tgcatttgtt tcagatatgt cgactggtta tagtgggaat ttaggttttc
     4141 ctatgcctag acaatggtct tttgatcaat ttgttgaatt taccatagga agtggcaacg
     4201 gagctgttgg tatcgattta atcgctacat cgggtagaga tagcggattt aatgagttat
     4261 caaatgatac taataatgat aattacattg ccaaatacaa tcagaaggtt ataaatcaga
     4321 tggtacgtgc gtatcaatat ctatcacaag ctggtcttga taatccttgg aaccctcatt
     4381 tgacatttta tagatatgta aattattctg gtttgtcatg ggacatcatt tcttctcctg
     4441 taacagagca tgatagaaaa atttatgatg aatataggaa taaattaact aatagcgagg
     4501 gcctgtataa ttattttata gatcctaata ctggttcaat aataggtttg cctcacttaa
     4561 ttgtgacgtt acaatcacag atgtttctag ccgacacaat caatgatagt gtttctgact
     4621 ttgcaggttg gttaggagat ttaatgactt gctggggtga agttaagaaa ttaggaatac
     4681 aaatggagca aggtgtattt gcattagtag gtacggctgc aggtggaaca tttagtctag
     4741 aagatttata ccaagatgtt gacgcggtaa atgtttatac cttagcaaaa agaaattctg
     4801 attcaacagc tttatcggct ttaaaaacgt actattgtga taagggtgct attgatagat
     4861 ttaatcaatt tgttaagaac agatttggtt cttcagataa aatcgcttca gtaacaaata
     4921 gtttattaga aaatgacgaa acagttgata tcttaggtgt agggataatt tcatttttca
     4981 ttgataaaat agttaataat tcacttggga cagattttac ttatcttgat tttattggag
     5041 atgaggggaa agttgcaaat ggattttctg aaaaaattat tcaatttcaa gaaaatagaa
     5101 gtaaacttaa ttaagaatcg tttactattt aaacagtgtc cttttccttt ttaaatatat
     5161 acgataaaat aagtatatga attgtaaaag gacatgatga ttatggaaga aatagaatgg
     5221 aataatctga ctcaaaataa taaaaataat tctggatgtg gaattatctt tatgtttgtt
     5281 atagttttgg gaatagtagt acttttaata actgtcaaga tagtagatta ctttgcgaat
     5341 actcctgaag aacaaataca gagaaaactt cctgagtttg aaagagtacc accttatgat
     5401 ccaagagata attcatttca agtaaaaaaa ttaaaagagt ctccaaatga aatgtggttt
     5461 gaagttacag ttgaatcaag cgacttcaaa gaaaaaaaga aagaatacaa ttatattgta
     5521 aaggcaaaag tatcaaaaag atttattttt aaccctaaat tagaaatata tagtgttgta
     5581 atagaataat agtgttaaaa aaattgtaaa agttaaagaa gtcaaattct gatgtgaaaa
     5641 ataaaatata ccatggaaga cataaaagaa aaactggata actagtttat ttaatggcag
     5701 accgttaagg cctgccattt ttatgtattt tagcggaata aatataatca tgcgggagtg
     5761 taaacttact gtttcaaaaa gtatactttt tgacatgcct tgattttctt tgtttatgta
     5821 tggcataata accacataat acaatttgaa acgtttctga tttaatctga ttgttttgaa
     5881 acaattttag tgaaaaaagg gtagataaaa acgatgagaa aattttttta tatccgggtc
     5941 agtagttatg atcaatcgat cgaacgacaa ctgatttccg cgaaggaatt aggaatccct
     6001 gaagaatata tatttgtaga aaaagccagc ggcaaagatt ttaaacgccc tgaatatcaa
     6061 ttaatgaaac ggatgtttcg aaaaggagat ttactctatc tacaatcatt agatagacta
     6121 ggcagaaata aacaaatgat tttagaagaa tggcgagaat taactaagga aaagcagatt
     6181 gatatttctg tgttagacat gcctctgtta gatactgcta gttacaagca actagatggg
     6241 ttagagacgc ttatctctga cttaattctg caattactca gctatatggc cgaagacgag
     6301 cggaaacgaa ttaatagccg gcaaagagaa ggcgtagaag ctgcgaaaca aaagggtgta
     6361 aaattcggca gaaagaaaat tgctttacct cctgaatttc ctgcgatcta ttctgactgg
     6421 aaagcaggaa agataactgc agtctatgct atggatcaat tgggcatgaa acgaaatacc
     6481 ttttatcgac gggtgaaaga atatgaacat accttgcacc acttttcttg atagatataa
     6541 cagctattag acgggaaggg agagtttgaa aatggactta acgaatcaaa gggtcgtttt
     6601 tactggaacg ctgcagcaaa tgacacgaac ccaagccatc ggtttggttc actctttaaa
     6661 cggccattgt caatcaagtg ttacttcaaa aacaaatttc ctggtttgtg gtcagtattc
     6721 taagtcgttg tttgatgatt ctctctatac aaaaaaggaa caaaccgcgc gggacttgat
     6781 tgcgttaggt catgagatta ccattttatc agaagtcgaa ttttatgcgt taattagtca
     6841 acagttgaaa gaatggcaac ggtatttata atcgttagta aaatttacaa ggaggaaaat
     6901 ttttatgaag cgaaaatctt atgatcgttg gggcattgaa ataactagtt ttaatcgaaa
     6961 tattgctttt cacgtggagt gtgactgtgg ggaattagca aaaagtgttt atcaaaaaaa
     7021 ttacttttac tgtcctaaat gccatcgccg atacggggta catggaacat agaaacgaaa
     7081 tagtgcggta gaaaagcgaa tgaatgtagt atatttctac aaatcattcg ctttctttat
     7141 tttataaata gttggtcgag agatcccgtt ttcttttgca atctctgcaa ctggaatgcc
     7201 ttgctttaac atgtccacca cggttttaaa aactaagcgt ttttgcggat ctgttgagtt
     7261 aatagaatac tcgattggtc gtcccttata tcggccggct ttttgagcca ataatactcc
     7321 ttgccgctga cgttcacgaa ttttctcacg ctcgttttgt gcaatataac ttagcagtga
     7381 taaaaacata tcgaacatag cggtatccag gagttcattt ccagtattaa aatctaaaaa
     7441 ctgtgcatct aatattttta acgctacttt tttctgtttc ataaaagcaa ctgtattttt
     7501 tatatcttca taatctcttc ctaaacgatc tagtgat
//
LOCUS       DACBYO010000117         7408 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.117, whole genome shotgun sequence.
ACCESSION   DACBYO010000117 DACBYO010000000
VERSION     DACBYO010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.117"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            428..697
                     /gene="rpsN"
                     /locus_tag="IVD26_002629"
     CDS             428..697
                     /gene="rpsN"
                     /locus_tag="IVD26_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAP6080541.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            712..891
                     /gene="rpmF"
                     /locus_tag="IVD26_002630"
     CDS             712..891
                     /gene="rpmF"
                     /locus_tag="IVD26_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAP6080542.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            923..1300
                     /locus_tag="IVD26_002631"
     CDS             923..1300
                     /locus_tag="IVD26_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080543.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1321..1470
                     /gene="rpmG"
                     /locus_tag="IVD26_002632"
     CDS             1321..1470
                     /gene="rpmG"
                     /locus_tag="IVD26_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP6080544.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1494..2477
                     /locus_tag="IVD26_002633"
     CDS             1494..2477
                     /locus_tag="IVD26_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAP6080545.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2507..2629
                     /locus_tag="IVD26_002634"
     CDS             2507..2629
                     /locus_tag="IVD26_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAP6080546.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            2647..4170
                     /locus_tag="IVD26_002635"
     CDS             2647..4170
                     /locus_tag="IVD26_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAP6080547.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            4194..4433
                     /locus_tag="IVD26_002636"
     CDS             4194..4433
                     /locus_tag="IVD26_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080548.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4626..5261)
                     /locus_tag="IVD26_002637"
     CDS             complement(4626..5261)
                     /locus_tag="IVD26_002637"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6080549.1"
                     /translation="MVRHLFVDFQWSPEKISNRLKHEHMDFSISFITIYRAICNDLFD
                     TEPLSHGNKGLIRSLHHRGKTRHTKNHVESRGKICLTHSIHGHPKSADDRSDFGHWKA
                     DIVAGKTSGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEVLNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5282..5500)
                     /locus_tag="IVD26_002638"
     CDS             complement(5282..5500)
                     /locus_tag="IVD26_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6080550.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            5809..6636
                     /locus_tag="IVD26_002639"
     CDS             5809..6636
                     /locus_tag="IVD26_002639"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HAP6080551.1"
                     /translation="MPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGISKPIPII
                     QAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVVEEEQDI
                     RGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVDLSKILN
                     TNLFNIDETSYSMGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFAHLTDKN
                     FPGNITRAKGFLWFAQHSDFSTIFETSGSHKSIESLNYWVASLPKIECQMIIQKNPN"
     gene            6825..7232
                     /locus_tag="IVD26_002640"
     CDS             6825..7232
                     /locus_tag="IVD26_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAP6080552.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
BASE COUNT         2625 a         1097 c         1447 g         2239 t
ORIGIN      
        1 acacgaaaga atcagtatga ttgaattagt tcacttaatg tctattctta taatataagg
       61 aataatcaaa gttttaaaaa attggcgata aaccagttaa acataaaaga ttgaataaaa
      121 agttatagtt tctttcatat tgccgtttta agtagaggaa aagctactta aaacggtatt
      181 tgtgtttgat tggactaata aaagtgaatt cttatttttc agagcttaaa ctgcatattc
      241 ttttaaatga tttgattatc tctatgtacc gataaattcg ttttcaaata gttatctatt
      301 catatgagtt ttatttcatg ttatttattg ttgacaagag caactcttgt tggtaaagta
      361 tcagtgtcaa aacgtaacga ttacgatttg agatgtctaa atcaaaataa aaggagtata
      421 aaggtatatg gcaaaaaagt cgaaaattgc taaagcaaag aaacaaatgg cgatgattga
      481 aaagtacgca gataaacgtc aggaattaaa agccgcagga gatcgcaccg ctctcgctaa
      541 attgccaaga gattcaaatc cgaatcgtct gaggcttcgt gatcagacgg atggtcgtcc
      601 aagagggtat atgcgaaagt tcggtatgtc ccgtattaag tttagagaac ttgcccatca
      661 agggttgatt cctggagtaa aaaaagcaag ttggtaaaag gaggaaatat catggcagta
      721 ccagcaagaa aaacatctaa ggcgaagaaa cggttaagaa gaactcatca aactgtagta
      781 aaaccagaaa tttcatttga cgaagcgaat ggtgattata gacgtagcca tcatgtatct
      841 ttaaaagggt actataatgg aaagaaagta attaaaggag cttcaaaata gtttaatata
      901 taacttttag gagggaatca aaatggaaat tatttaccca cctttagttg aagaaggatt
      961 aaagtattat cttgaaacga cccagcaatc gctagataaa tgcacttttt atcgttcgat
     1021 ggtagagaga ggaattatta ctgaaacggg tttaccgacc caacaggcaa ttgaaaatgg
     1081 attagtcaaa gattactatg aggaccaagg cttatcattt gatgattttt taagaatcta
     1141 tccaattttt gaagagtatg acgaggagtt atttcaatgt attgatggtt attgggagat
     1201 acctgttgat atgaaagaaa atttagtttc acaattggaa tctggcgagt taacttttga
     1261 agatgcacaa caaattcaag catatcttga agatcgataa gtattgaagg aggaagattt
     1321 atgcgtcaaa atattatttt ggaatgtgtc gaaactggag aacgtctgta tctcaccagc
     1381 aaaaataaac ggaataaccc tgaacggtta gaattaaaaa agtattcgcc aaaattgcgc
     1441 agacgggcaa ttttcaaaga agtgaaatag ctaagtggta aaaaggtgac aaaatgggca
     1501 taccagttac aatcgtttct gggtttttag gggctggaaa aacaacgcta atcaatcaag
     1561 ccttgcaagt ctcaccctac cccagggaag aaattattat aattgaaaat gagtttggtg
     1621 aagttgggat tgatcacaaa ttattagttc atagcgagga acgggtgtta caactaaata
     1681 atggatgtat gtgttgcagt cttcgcagtg atttattagc aatattgatt tctttactgg
     1741 aaacaataga agaacatcaa caaccaattt cacaaatcat cattgaaact acaggtatag
     1801 cagatcccca accaatcatt caaacacttt taacagcgcc tcaactaaga ggaagagtat
     1861 atatcgatag tttattgact gttattgata gtgacagttt tgaacttatt gaaagagaac
     1921 cacaagccct taagcaactt gtcatagcag atcgcatttt tgtgtctaga aaacaaaact
     1981 tgaatttatc tgcactaaaa aaattacaga gagaaatcaa aagtattaac cctttatccg
     2041 atattcgaat gttcacacat agtgaaacga ttcaaaaaaa ggatttttat aatttggaaa
     2101 aattcaatca tcccttagtt tttgaaagtg attcatcaga aaatcactat aatggcaaac
     2161 actatcatca acatcatcaa gaacatgagt ttaaatcaat tctcttaact tcagatcaag
     2221 acataaaaaa agatttttta ttccaattaa ttgaccggct gattttaacc aaccaaggga
     2281 gcctgtatcg ttttaaagga ttgattgctt tgcaagatca agattttata gttgccatac
     2341 aaggggtaaa cgaacaggtt aattttcaat acaccactcg acaaaaagac caaaccacta
     2401 ttattctaat tggaaaaatg ttggatgaag aaaggatcaa acagagtttt gataaattac
     2461 tggcggaaag caaataatga taagtattga ttaggggtaa tttctaatgg agaaaacgga
     2521 tatatctagt gcatatcgac gacttaaaag cccgaatatc aaaactagaa aaagggcatt
     2581 aaaaattatc aaagaacata aacaaaataa aatgaagaaa ttagcataat taaggaagga
     2641 aaaagaatga agaaaatcag tgtaggactt attgggatag cagctctagg attattggga
     2701 gcttgctcca gcactaatga tgcaaaagta tcgaatgata aagatggaaa attagaaatt
     2761 gtaacaacat tctatccaat gtatgatttc accaaaaaca tcgtcggcga tgaagcgaac
     2821 gtggatttaa tggttccagc gggatcagaa cctcatgact atgagccctc agctaaggat
     2881 atggcaaaag ctcatgatgc tgatgttttt gtatatcata acgaaaacat ggaatcatgg
     2941 gtaccaaaag ctaaagaaag ttggaagaaa gctgggccta atgtagtaga aggaacaaaa
     3001 gacatgattt tattgccagg tagtgaagaa gaagatcatg atcacggaga agaagatcac
     3061 catcatgaac tagatcctca tacgtgggtt tcacccaaaa tggcaattaa ggaagtttca
     3121 aatatcaagg atcagttagt taaattgtat ccgaaaaaag caaaagtatt tgagacaaat
     3181 gctgaaaagt atttgactaa actgaaacgg ttggatgctg actataccac tagtcttaaa
     3241 gaagcgaaac aaaaaagttt tgtgacacaa catgcagcct ttggatattt agctttggat
     3301 tatggattga tacaagttcc tattgctgga ctaagtcctg aagaagagcc atcttctggt
     3361 cgattagctg aattaaaaga gtatgttaaa aaaaataaga tcaattatat ttactttgaa
     3421 aagaatgcta atgataaaat cgcaaaaact ttggccaatg aagctgggat aaaattggaa
     3481 gtattgaatc ctcttgaaag tcttacaaaa gaacaaatgg ataatggtga agattatgtt
     3541 tcagtaatgg aagacaatct aaaagcgtta gagaaaacaa ctatggttgc tggtgaagag
     3601 gtagttccag aaaaagaagc gaaggatgaa aagacagttg ctaatgggta ctttaaagat
     3661 gccgatgtga aggatcgcga attgagtgat tatacaggcg aatggcaatc tgtttatccg
     3721 ttgttaaaag atggaatttt ggatgaagtt ttcgattaca aagcaaaact caataaagac
     3781 atgacagctg ccgagtacaa agattattat actactggct ataagacaga tattgatact
     3841 atcaacatta aagacaacac cattgatttt gtagtcaacg gtgaacatca tcaatacaca
     3901 tacaaatatg ttggatacaa aattttgaat tatgaaaaag gaaaccgtgg tgttcgtttt
     3961 aattttgaaa ctgatgatgc aggtgctggt cgttttaaat atattcaatt tagcgatcat
     4021 ggaattgcac caagtaaggc agagcatttc catattttct ttggtggaga aagtcaagaa
     4081 aaactttata atgaaatgca taattggcct actttctatc cagcttcatt atctgagcat
     4141 gagattgctc aagaaatgat ggcccattaa aatccaatct ttggaggaaa tacatggtaa
     4201 gaaaagtatt attgtctatg gattccaaga atattgatgc ttatcggcgt tatcaatttg
     4261 caaagcaaat gagattaaat gggagtacat tagctgatat tgctgcaact ttacatgtta
     4321 gtattgacac agttcataga gtattaaaac gggatcctga ttgttgtttt atcaaggtca
     4381 atactggaag aagtagacgt ttagcaaaac ggcataatag cttggccaat taattgataa
     4441 taccagagta gatcattttt cccttatttg gatttgatct gctttttatt atttcttgaa
     4501 ttgtcaaatc aagcgcaaca ctttatcaaa gaagacttca taaggtgttc tccaatctaa
     4561 acactttcta ggtctgttat tcagtttttc aatcatctga tttatcgttg agttatctac
     4621 cgtagctatc tctttcgatt ttggcaagta ttctcgaatg agtctattcg tattttaatt
     4681 tgttcattgt tgccaagggc atgaggatct ggaaaataaa agggcatatt attcaatact
     4741 tctgtaactg cgaaatgatt ggagaattct tttcctctat ctggagtgat cgttttgacc
     4801 gcctcatttg gaatactgct taaaagttca atcattttct cgctcacata agcggctttc
     4861 tttctgggga ccttctttcc tgctaaaagg aagcatgatt ttctgtctgt caaagtcact
     4921 aaacaagtac cactagtttt gccagctaca atatcggctt tccaatgacc aaaatcactt
     4981 ctatcatctg cggattttgg atggccatgg atcgaatgag taaggcaaat cttcccacga
     5041 gactcgacat gattttttgt atgtcttgtt tttcctcgat ggtgcaatga acggatcagg
     5101 cctttattgc cgtgtgagag gggttctgta tcgaaaagat cattgcaaat tgcacggtag
     5161 atcgtgataa aactaattga aaagtccata tgttcatgct tcaaacgatt cgagattttc
     5221 tctggcgacc actgaaaatc gacaaataaa tgacgaacaa ttgaccaaac tcacggatca
     5281 tttagaatgt gataacgtcc gcattttttt cttcgataag cataattttt ttccgctttg
     5341 gaaggtgatt agtttttttc ttgtttcttc tcagttcatg taaaatagta aacgggctat
     5401 gctgaatgtc gttgccaatt atactaatag aaaatccttc ttcgtgaagc agaaagattc
     5461 tttctcgttt gagtatagta agatgacaat actggctcat aattattttc cttctaggag
     5521 tgttctcgac aaacttatac tagttggata tcgattatga ctcattttta tgtgttgcac
     5581 ttaaagtgta aattcaaggt atagaaagag gttccctatg aaaaaatacc tattacaatc
     5641 ttaactggct atcttggttc aggaaaaacg atacttctaa atcatattct gtacggtgat
     5701 cacggaaagg aaattgctgt cattgtaaat gacatagggg aagtaaatgt tgatggggta
     5761 ttagtcgaca agaaaggttt taaaagaact ggagaaaaac ttgtttcgat gccgaatgga
     5821 tgcatttgtt gtacattacg cgaagatttg attgttgaac tagatcaatt agtgcaattt
     5881 tctgacttga atcaaattgt tattgaagct tcaggaatca gcaaaccaat tccaattatt
     5941 caagcaatta tattagctaa aaacccttta gacattgatt tgacccaacg attagagatt
     6001 ggtgccatta ttatagtagt ggatgtaaaa cgtttttggg ataatttcga aacgggtgaa
     6061 aagattcagg aaagaaaagc tgaaggtaat gtagttgaag aagaacagga tattcgtggc
     6121 ttgttaattg atcaattcga gtgttgtaac atattacttt taaataatag tgacttagtg
     6181 tcaaccaaga cgatttacaa aattaacggt ctaattgcta agttacagtc caatgccaaa
     6241 ataattagga caattaaagg tgaagtagac ttatcgaaaa ttctaaatac aaatcttttt
     6301 aatatagatg agacttccta ttcaatgggc tggttcaaag agttagagct tggctatcaa
     6361 aatcatattc ctgaaacaga agaatatggt atctcaagtt ttatctatcg aaatcggtta
     6421 ctccttgacg cacaaaaatt tgcccatctt acggataaaa attttcctgg caatattaca
     6481 agagcaaaag ggtttctttg gtttgcccaa catagtgatt tttcgacgat ctttgaaaca
     6541 tcgggtagcc ataaaagtat tgaatcatta aattattggg tagctagttt acctaaaatt
     6601 gagtgtcaaa tgattataca aaaaaacccg aattgaagga agcctggcat ccgttgtttg
     6661 gtgaacgcat taataaacta gtttttattg gtatgaagat ggatcaacaa tgtattaagg
     6721 aacaacttga gggttgttta actgattctc ttaatgcaga taatttccga aaaatttcac
     6781 catttccatg gaaaaattct aatatgttta gccagatatc gttaatgaaa tttttaagaa
     6841 aagctggtgt caagataggc gatgtcataa ttattggcat tttgattatt ccctctttta
     6901 ttcccttatt tgtattctct atagaaaagg agaatgaaac aactgaagat gctatcaaat
     6961 atgccatcgt tcaaattgat ggcaaggaaa tggatcgctt cgatttggat aagatcaatc
     7021 ataaactcgt gaattatcat cctgcgaagg gacaatataa tattgttgag attaaagatg
     7081 gaagaattcg agttaaagaa gataatagtc ctgatcaaat cgcggttaga actggatgga
     7141 tctcaaaacc cggtcaaacg agtatttgtt taccccataa gttagttatt agtattgaga
     7201 aaaaagaaag caaagattac tacatttact aatctggaaa tagatgagga ggtttttaat
     7261 aagaaaaaga tattattatt aataatagca ggggctttat taagtgtgtt aagcgcttgt
     7321 ggacaagaaa aagaagcggt gacaacaggc acaagtatct ttaacgggac ctgcaatggt
     7381 ttagttaaca gtcggttaga ttacttat
//
LOCUS       DACBYO010000118         7283 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.118, whole genome shotgun sequence.
ACCESSION   DACBYO010000118 DACBYO010000000
VERSION     DACBYO010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.118"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(170..3319)
                     /locus_tag="IVD26_002641"
     CDS             complement(170..3319)
                     /locus_tag="IVD26_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HAP6080553.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWSNLRQ
                     KIISNNQAELNDSPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIERENPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIIQIELK
                     QVTAKDGFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGVSSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEE
                     QIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHA
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3333..4550)
                     /locus_tag="IVD26_002642"
     CDS             complement(3333..4550)
                     /locus_tag="IVD26_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAP6080554.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLGDMMDVTSVKRIHQSDWTNSG
                     IRFLRARDIVSAAKNEEPSDYLYISEEKYNEYSKNSGKVSQGDLLVTGVGSIGVPLLI
                     TDDNPIYFKDGNIIWFKNEHKIDGNFFYYSFINNKIQKYIRDVAGIGTVGTYTIDSGK
                     KTPISLPTYDEQIKIGSFFKQLDHTIMLHQHELDLLKETKKGFLQKMFPKNGAKVPEV
                     RFPGFTGDWEERKLGEVVVFLNGRAFKQQELLDSGKYRVLRVGNFNTNDRWYYSNLEL
                     EEDKYANKGDLLYLWATSFGPEMWNEERVIYHYHIWKLKFLSKELDKQYLYTWLLTDK
                     EKIKESTNGTTMVHVTKGGIEQRTFQFPPDINEQQKIGAFFKQLDDTIALHQRKLDLL
                     KETKKGFLQKMFV"
     gene            complement(4540..6135)
                     /locus_tag="IVD26_002643"
     CDS             complement(4540..6135)
                     /locus_tag="IVD26_002643"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAP6080555.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYSISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            6260..7045
                     /locus_tag="IVD26_002644"
     CDS             6260..7045
                     /locus_tag="IVD26_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SinI family restriction endonuclease"
                     /protein_id="HAP6080556.1"
                     /translation="MPNKNRTFESILNEGLTTEPASIIFDEVIDDVEDSKYHKNLKEL
                     FYFALNNGPSLFTGISVPDSDNPLIMAKIYLTKWCNKYIRDRNNPALKKPLKTFGEKD
                     AALTTRVAANANIDDQKVLNDYLRGHFLYMSAENMNGSILEEYLAEVLEPEGWIWCAG
                     SVYRAVDFCYLGTSPILLQVKNKYNTESSSSSAIRVGTTIRKWNRLNKSTKISGLDSP
                     IPNWKALIEMTEASKELAAKLTENSYLAYINEKSTRELWTLDD"
     gene            7038..7280
                     /locus_tag="IVD26_002645"
     CDS             7038..7280
                     /locus_tag="IVD26_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080557.1"
                     /translation="MTNNILISIYPRYMEKIINKQKNFEFRNFYLTSDPYNIFWIYET
                     IPTKALKYKLIVKNPITKLKKNQHYFLGDDEFEQLV"
BASE COUNT         2132 a         1477 c         1199 g         2475 t
ORIGIN      
        1 tgcaacagaa ccggtaaatg aatgaaaaag atggaagaat cattattcaa tagctttctt
       61 aaatactccg ttataaaatg tgaacaagta aaaagacatc tatccctatt ttctacactt
      121 ccactttact actatctttg aatcgtacaa ttttcttaac tcttctcgtt tacctcaatt
      181 cattttcaag tggaatcaac tcatcatcta acattttacg ccatgctcgc ttcatttctt
      241 gtgggtattt aaatggtttc gcttctggat gtttggcttt atatccttcg taatccttac
      301 tgttgataat tgctttcata ttaggaattg gatcttcacc tggcatatat tgcagattag
      361 aagcatgtaa ttctttctca gaaacaaacc actcattgga aaaggcatga atcaaattat
      421 cacttgcttg tgtaaaatag cgacgtttaa tgacaaagat atcttcatta ctatctaaag
      481 tccccacatc aaatgcattt aaaatttgtc ggtaaacttc tttgactcct tctgttttat
      541 tcaatttagc caaagctttt tcaatttctt ctcgtgcatc tgaactattc gcagcataag
      601 ttcctagtaa ttgatcaata taagtagaat caatatcata caacttagtg gtattttcac
      661 tataaaattc gatcgttgaa aaatcttctc cctctttttc tggttcttcc tccatcaatg
      721 aacccttcac ggtctcgtac acgccaattt gttcttccaa aagttgaatt tgattgttca
      781 aagttgaaga ttgcaccatg tcatcattgt aatcatcata agtcactaac gattcatacg
      841 cacgattcaa ttcttgaaat gctttgacgt actcgatacg gatttcaagt ggcgtatgtt
      901 catcaatgga ttccatggat gaaacctctt ttaacttacc atatgcttgc ttgaatcttt
      961 ttttggattc ttggtaactt ggataaatca aacccgattc ttctttagct tctgaataca
     1021 gttttgtcgc atcctcgaca ttcttctcca ttgtcgctgg ctttcggaaa gtaacaatta
     1081 gtccttttgt tttttcagga tacgtacggt tcgtacgtga aaaggcttgg atcaatcctg
     1141 catactctag attacgatcc acaaataggg tttgaatcgt aggggcgtca aaacctgtca
     1201 atagacgatc cactacgatt actaaatcga tttgtttccc aaattgtttg aattccgctc
     1261 tttttcgtgc caaacgatta ttgatgtctc cgttataacg ctcaatgtct gctagtgacc
     1321 aggcagtatc ataatactga ttatattcct caataatttt ttgcatttct tcttgttggg
     1381 cacttgaatc tcggctattt tcttctaatg aataggtaat agcgattcgt gggaaatcag
     1441 gatcctccat cgttcgtcct tcacggatag gctgattggg aaactctttt attaaccaat
     1501 cagattcttt cgtcatctct ttgatggccc gataatactt tttggccata tcaatggaac
     1561 tcgtggttaa gatcgcagac ttcgttggac ggccatttcg aaaatcaaat tttgtatagg
     1621 cattgtctgg acggaacatt ttatgaatga ctttttggat atgttcctct gcttcaaaaa
     1681 cagtagggtc caaataactt tcttttttga cagactccat ttgatcgatc atacgattga
     1741 tctgttccgg tgaatactct gcatatgttt ctacttcttt taatttccga tagattttat
     1801 tctctaatga agtcggctcc acggtgtttt catgctctac ttgaaatcct aaaaccgagc
     1861 catcttctaa tgcattcttg atggtatagg tgtgcaagac ctctccatac tgatcatggg
     1921 tcgtacgtgc caattgccct ttggcttgtt tccgattctc agggaaaatc ggtgtacctg
     1981 taaagccaaa ccaagtggat ttcggaaaca tttttttgat ttcttccata ttttcagcac
     2041 ttaacgctcg atgacactca tcaactacaa acacgatatg ttgccccatt aatttttgga
     2101 agcgattggt tccttttttc tcttcctgtt tctttgcata tttcaacgcc gcatctagtt
     2161 tttgacgggt tgtaatgatc acaacattcg cattggcatc tgccaacaga gtttcactta
     2221 actctttggc acttcctgtt cccacgatca agctattcgc tttggcatta ccagaagaaa
     2281 ccccagtatt aaactccgaa gcaaatttcg taaactctgt ggtggtctga ttatctaaat
     2341 ctttgcggtc cactaacatg atcgttcgat cgatccccga ttttcgtgct aaaagcttag
     2401 tagatacaaa actagtcaac gtctttcctg aaccagtcgc atgccacaca taccctgatt
     2461 gatgtttatt tgcggcaata aacaaggctt gaatcgcatg cacttgataa ggatgtaaca
     2521 ccatgagggt tttattgtct tgatcttcac tgacaatcgt ataatccgca atcaagcgat
     2581 gggcatctgg gatatttagc acttgtttgc aaaactcata taagttttct acctttttat
     2641 tatctttcgt tcgccaacta aataaaaact taggatgcaa atccttcggt aaggcatttg
     2701 caaaataccg agtcgtttgt tcattggaaa ccacaaacaa ctgtaaggtc gaaaagatat
     2761 tgttccgaaa catgccttct tcagcatatt ttttgatttg attaaacgcc tgataaaaac
     2821 catcttttgc agttacttgt tttagctcga tttggataat cggtaagcca ttgatcaata
     2881 aggtgacgtc aaaacgtcga tcccgcgctt ctatgttact tccacgtttt gcaatttgat
     2941 ggaccacttc ataagtagag attcctccac caatgtcttg attggaataa aggataagtg
     3001 agacagaacc caattgcgga ttttcccgtt caatcgtgat ccgagccatc ccattttcac
     3061 cttttaacca tttcgcagca tcaaatgggg ttttcgtccg tagcaataat tcggttttga
     3121 tcgtttcaaa ctctttatcg gtcaaaggag aatcattcag ttctgcttga ttatttgaga
     3181 tgattttttg acgtaaattg ctccaaagat cttcttctga ttttagatcc ggacgatacg
     3241 tccactgatt atgtccttcc ccgaggacac gaatcaactg ttcttcgact tccgcttcct
     3301 cacggtgact aattttcatt cttcttccct ccctaaacaa acatcttttg caagaagcct
     3361 tttttcgttt ccttcagcaa atctaactta cgttgatgaa gagcgatcgt atcatctagc
     3421 tgcttgaaga aggcaccaat tttttgttgt tcatttatat ccggtggaaa ctgaaatgtc
     3481 ctttgttcta taccaccttt agtcacatgt accattgtcg ttccgttagt tgattcttta
     3541 attttctctt tatcagtcaa tagccaagta tatagatact gtttgtccaa ttccttagat
     3601 aaaaatttaa gtttccaaat atgataatgg tagattacac gttcttcatt ccacatttca
     3661 ggaccgaagc ttgttgccca taaatataag agatctcctt tattagcata cttgtcttcc
     3721 tctaattcta agtttgaata ataccatcta tcattagtat taaaattacc tactcttaaa
     3781 accctatatt ttccagaatc aagtaattct tgttgtttaa aagctctacc attcaaaaaa
     3841 actaccactt cccccaactt ccgctcttcc caatctcccg taaatcctgg aaaacgaact
     3901 tctggcactt ttgctccgtt tttagggaac attttttgta agaatccttt tttcgtttcc
     3961 ttcagcaaat ctaattcgtg ctggtgaagc atgatggtgt gatcaagttg tttgaaaaat
     4021 gaaccgatct tgatctgttc gtcataagtt ggaagtgaga taggtgtctt tttaccacta
     4081 tcaattgtat aggttccgac ggttccaatg cctgcaacgt cacggatata cttctgaatt
     4141 ttgttattta tgaacgagta gtaaaagaag tttccgtcaa ttttatgctc attcttgaac
     4201 caaatgatgt ttccatcctt aaagtaaatt gggttatcat cagtgattaa taaggggaca
     4261 cctattgatc cgacaccagt tacaagcaag tctccttgag aaactttacc tgaatttttc
     4321 gaatattcat tatatttttc ttctgaaatg taaagataat cggatggttc ctcatttttt
     4381 gcagctgaga caatatcacg agcacgtaaa aatctaatac ctgagttagt ccaatctgat
     4441 tgatgaattc gcttcacaga agtaacatcc atcatatctc ctaacttacg ctcttcccaa
     4501 tcttccgtaa aaccaggaaa ccggatttct ggtcgtgtat cattgctcat gtttgaacac
     4561 ctccagcgca ccttgtaacc acgcttcatt ttcaggtgtt gtttgcaggg aagagatagc
     4621 ttctaaaagt tctttttcta gcacttgctg ttcttgtcgt atcttcttga tgtcatttcc
     4681 gacatgaacc atatcaattg gttcttcttc ttcgaaagta tcgacatagc gtgggatatt
     4741 taagttatag tcattttctt tgatttcatc aaaggttgcc aaatgagcgt atttctcgac
     4801 atcttttctt tcagcgtagg tttcgaggat tttttgaatg ttttcttccg ataatttatt
     4861 ctgatttttc cctttaacaa attcacgact agcatcaatg aataatacat ctcgagtttg
     4921 acgattcttc ttcaatacaa tcaccgtcgt tggaatcgat gtaccaaaga acaagttcgc
     4981 aggcataccg atcacagcat aaatactgcc gtcttctaat aatttttgac gaatgacccc
     5041 ttctgcagca ccacggaata aaaccccgtg tggcaagacg atagccatag tccctgtttc
     5101 cttcaaatga tagaaaccat gaagaagaaa cgcaaaatct gctttggatt ttggcgctaa
     5161 tttcccgtag cgattaaacc gagaatcatc taagaaggtc gtatctgctg accaattagc
     5221 cgaataaggt ggattcatca ctactgcatc aaatgtgtaa ggttcatctg ttggccagtc
     5281 cttattcaac gtatccccat tgcggagatt catttcttcg gcatctaccc catgtaaaat
     5341 caagttcatt tttgctagat tgtatgtcgt tgtatttagt tcttgcccat gatatttaac
     5401 gttatctgga tgagttaagt agttacgtac atttaacatc aaggaacctg aacccatggt
     5461 tgggtcaaag acactaaaga atcgtcgttc tttttgatcc aacgtcacga tttgtgccat
     5521 catatcagaa accatatgag gcgtgtaaaa ttctccggct ttcttccctg cttctgaagc
     5581 aaattgactg atcagaaatt catacgcatc cccgatcaca tccccatcgt gacctaaaac
     5641 ttccacgtca ttcaatttct tgataacttc ggtaatcgtc acatttcgtt gttgctcatc
     5701 tgttcctagt ttttttgatt ggagatccac atcatcaaat aacccattaa attgattgta
     5761 ggtagatgcc aattgcacaa aggctttgtt tagatcgttc aattggaacg ttgcttgttt
     5821 tgcttgatcc gctaagacgt tgaaaagata ctctggtgag atcgaatacc ccaaaatatc
     5881 aacgattgtg gcaatcaggt cttcttttga ttcttcatct gaaagtaatt cacgatacaa
     5941 cattgtttgt ttgcttactg tgtcatattc ctctaaggat tcatctgcta aaagaaccac
     6001 ttgttccaac aaacggtcgg ataaatattt atagaaaatc agtcccaata aataattttt
     6061 atattctgac gcatccattt tactacggag attatctgcc gcactaaata atttttgatt
     6121 taattctgca cccaaaaaga tacactccta tctcttattt aaagttgcta tataccctct
     6181 tattttagca tactcccttt tagaaaaagc aaaaaaaaaa gaaaaaatct tattcttgat
     6241 aacaagctac gtgacgtata tgcctaacaa aaatagaact tttgaatcaa tcttaaatga
     6301 aggtttaacc acagaaccgg catccattat ttttgatgaa gttatcgatg acgttgaaga
     6361 tagtaagtat cataaaaatt taaaagaact tttttatttt gcactcaaca atggaccaag
     6421 tttgttcact ggtatatcag tacctgatag tgataatcca ttaattatgg caaaaattta
     6481 cttaacaaaa tggtgtaata aatacatcag ggataggaat aacccagcat taaaaaaacc
     6541 tcttaaaaca tttggcgaaa aagatgctgc tttaactact agagtagcag caaatgctaa
     6601 tattgatgat caaaaagtat tgaatgacta cttgcgtgga cattttttat atatgagcgc
     6661 tgagaacatg aacggaagta ttttagagga atatttagcc gaagtgttag aacctgaagg
     6721 ttggatttgg tgcgccggct ctgtatatcg agctgttgat ttctgttatt taggaacctc
     6781 accaattctt ttacaagtga aaaataaata caatacagaa agcagttcga gttcagctat
     6841 aagagtagga acaacaatta gaaaatggaa tcgtttaaat aagtcgacaa aaatttctgg
     6901 tttggatagc cctatcccca attggaaagc attaatagaa atgactgaag ctagtaagga
     6961 actggcagct aagttaactg aaaatagtta tttagcttat attaatgaaa aatccacacg
     7021 agaattatgg acactcgatg actaacaata tccttattag tatctatcca cgatacatgg
     7081 aaaaaattat aaacaaacaa aaaaactttg aatttagaaa tttctatctt acctcagatc
     7141 cttataatat cttttggatt tacgaaacaa tccccaccaa agctttaaag tataaattga
     7201 ttgtaaaaaa tccaattact aaacttaaga aaaatcaaca ctacttttta ggagacgatg
     7261 agtttgaaca attagtttaa aag
//
LOCUS       DACBYO010000119         7263 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.119, whole genome shotgun sequence.
ACCESSION   DACBYO010000119 DACBYO010000000
VERSION     DACBYO010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.119"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..2224)
                     /gene="pglX"
                     /locus_tag="IVD26_002646"
     CDS             complement(<1..2224)
                     /gene="pglX"
                     /locus_tag="IVD26_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HAP6080558.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     Y"
     gene            complement(2288..5959)
                     /gene="brxC"
                     /locus_tag="IVD26_002647"
     CDS             complement(2288..5959)
                     /gene="brxC"
                     /locus_tag="IVD26_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HAP6080559.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(5984..6559)
                     /locus_tag="IVD26_002648"
     CDS             complement(5984..6559)
                     /locus_tag="IVD26_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HAP6080560.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(6559..7158)
                     /locus_tag="IVD26_002649"
     CDS             complement(6559..7158)
                     /locus_tag="IVD26_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HAP6080561.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         2147 a         1372 c          963 g         2781 t
ORIGIN      
        1 cataccattt tctaaaacga ccacctttag ttgtaggaaa ccattttttt ctagactttt
       61 tagcgtcctc taatgtttta gcatcaaact ttattttgtt aaattctact tcaaaccaat
      121 accgcaaaaa tttattgtta tttccggttg ccaacccttg ttttgcatct gcaacatcgt
      181 tagttaattt tccttgagca aaatcagtga ttacgttatc gcttgcccag taagcaatcg
      241 gcattcctgg gatttttttg aagttgtctt gattagtact ataaaaataa tcgcattcac
      301 catgctgatg aattgcttct aacgttttaa ttttttgaac ttccattcca cctttaaaat
      361 ctgataattt tatatagctt ccatcttgtt catttgaatt ttttatcgta aacgtacaaa
      421 ttggaacggt tgcttcttca aaagctgaat actccatttg aatcaaacta gaaatgtttc
      481 tttcattaat taaaaatgag cgtaactttt catagctaga aatgaacatc caaacaaatg
      541 gcgtcataaa ggaagcatat ccattatcaa tcagcatttg gctattcaat ttaataaaca
      601 cagaaaatag atcttttttg acatcagaat agttatcatt tacatatttt tttaatttct
      661 tatccatttt attaagataa ggcggattag tgactaccgc tacatattta tcaactagca
      721 tttcagccac gtcaagaatg tgcaagtatt tttcttgtat ttccttcatc ccataaagaa
      781 tatccatatt cgtaaattcg ttgaattttg atatatactc tcttactttt cctaagtatt
      841 ctttagttat tgcctgatta tttttatcga ctaacttaat gattgatcca agttctttcc
      901 cattttcaaa ttgatcaaaa attaactctt tgtattcatt ccagcgttca ctatacttat
      961 cattgttcaa ttcactaata cgctcttgat actcgtctgt cactttagga gaatcaataa
     1021 actctcttaa attcggcgat agactttttt tcaaaaaaag acgatcgtat tgacgccctt
     1081 tcatcataat tgcaaaataa gacaattgat acgctctttt atcgatttca agaccatata
     1141 aattgtattc aacgattgca cgtgcagcat cacgctcaga atatcctaac gtaagataaa
     1201 tttccatcaa tacatcgaag gcgtaaacta aaatatgccc agaccccatt gcgttatcga
     1261 taatttttag ttcttctggt tttaaattac ttacagatgt tgcttgttca aaagcatatt
     1321 tatctggaat taagtatttc aacttatttc ttaattcact attgggataa tgatctaacc
     1381 aatactttcc taaactattg tcaaccatat aacgaacgac ccaatctgtg gtaaatagtt
     1441 gagttgctgc cggaatatct tgttttttga caatcccttt ataaatattc accacttgat
     1501 tatgtggctc actattatag tactgataca accacccaat aatctctacc tgtccaccag
     1561 cttgaacata gaaatcatcc tctggaatac ttaaaagatc agcgattaca ccatcttttt
     1621 taatataaga agctgtaaac aaaagttctg tataatcttc tacttcttca aatagctcag
     1681 gtaagtaatc attcaattga ttacagattt ttataaaaat caattgatac agcttgtcca
     1741 ttgcttctgc tgaattatct gttttccaag ttctgacttg ttgctgttca ttactagata
     1801 attcttcaaa gatatcggca tcataaatat ctgtaataat atctggctca attttcccac
     1861 ttatttcact agataataca cgatacgtgt caggtaaata atcatttacc tccataaacc
     1921 gaatggcaat caatcggtta aaccacgtat aagcaacctc ttcgattaac tcttgaaaag
     1981 cttctgaata agaagtgaca gaagcacgtt gttttagttc tgcaatcaat ttgtttcttt
     2041 gcgctatttc ttttccttga attcttattc ctgatttttc gatttcttgt aaattgctat
     2101 caattttctt cacatcttca atttttgatt catcaattcc taaacgtttt gctttagtca
     2161 ttacttcatc aattaatttt ctacgggcat tgaccgcgaa attctttatc gctttcttat
     2221 ccatttttct ttcccttcta tatgtaacct ttgaaaagac aggcaccttt ttatgcctgt
     2281 cttttcacta gaattgaatc gtgatttctg tattttcttg aagttgttcc ttcagttttt
     2341 gattaatttc agctgttaac tcatcaatat ctgctgctga cttaatagtt ttaacatgaa
     2401 cgttaagtgt tctcattggt actgttttct gttgaatagt aggttttact atcgctattt
     2461 cttcagcttt tgctgcagag tctatttcat ctttttcagt ttcacgaatc aagtttgctg
     2521 cttcaatttg tttacgtgct tgttcttctt gacgtctgcg gttttcttca ttatcgaaac
     2581 gttgattaaa gatcaaatac tgttctgcta cgtttaatga taagaaaaca agatcatcta
     2641 tagtattcgc ttgttcaatt tttgctttca gttcttgaaa ttcttggtca actattggta
     2701 caaattgatc cttaaaatct tttccttcta ataatttaaa tgttgcttgt ttttcttccg
     2761 ttaatttatt taatatttcc tgactttcca actctaacag ttgattatat tgttcaataa
     2821 attcttgaat caactcattt agtttcatca tatctgaata aggatcagcc tttttcaaaa
     2881 tggttttcat ctcatgaatc aattgatcaa tttcttggct agaagtttga cgccgacttt
     2941 tttcgattaa tctaatttta tcttgtgcat tctcccagat ttttttctga gtactatttt
     3001 gcttgtggaa atttttaatt ttatcatatg tttcagccca gtcgaataat tcatcgcgat
     3061 attttttgat tgtataaaaa aagtcttcaa catctgacgt ttgaacaatt acttcaagat
     3121 atttttttat ttgctcatat tcataagcac tagggtaggt ataagtgttt tgtaaatcaa
     3181 aataagagcg taaattgtct aattgacctt ttaaatattt cttgaaattt tccattgtat
     3241 gttcattgtt attttcatca acaatattac gactttgaaa cagttctcta ccgatttcgt
     3301 caaccaattt ttttgctttt ggcgaaatca ccgcgcttgg ttcaattttt atcttttcac
     3361 tttctcgtcg tttttgaata atcattacaa tactatttgg atcatccatc cgtgaaattt
     3421 gtacattgtt ataaagtaaa tcaattttac cagacatgaa aagtttagcg atgcaccatt
     3481 ccacatcaag ttctgtgaat ccatacggtt gttttgtttc aaaacgatca cgaattgttt
     3541 tcatcgtaat cgttaggtga tttctctttt gatcattgat aaaattgaaa atttcctgaa
     3601 ctgcttgctc atttgatgga tcttcaataa tttcattttt gctttctttc actaaatata
     3661 agatatcttc tttttcttta ggcgcatcaa tttggtttaa tttatggtat acttcttcag
     3721 ccattttctg aagtgctgat tggaattttg ctttaaagtc ggagcctgtc agttgaattt
     3781 ctgcaccgtt atagaaaaat tttgcagatt tcaacagttc atttaattga tcgttgatac
     3841 ttgcacttag ttcctgtaat tcaccagatt tttccgaacg aatcgcgtca aagttcttta
     3901 ctacactcga ataagtcgtt gttaaataaa gattcattct agcatacatt gctatatcat
     3961 ctttaaattc tttatctgat ggcaattcta cgaataataa gttacgggaa ctcttaagcg
     4021 caagttctgc ctcttgacct gctaaatcag agtatggtga aataaaatta actgtcattt
     4081 cagcatttcc agcttgcttg tatggacgtt gatctaacac ttgtgcataa gtaaacgtat
     4141 accggttttt aaatttattt ccacctgaca tgcctaattt ttcataggca aaactatttc
     4201 ggtctagaac gccgtcaaaa attcgtttag atagttctac gatcaaatca ctatctgtaa
     4261 tattttgatt tttaatctca cgagtaattt cctgttcttc atcagtttgg aaaatataac
     4321 tatctaagtt cttccgcaca aagttttcct taattaaaag gtccaatgct tcttctactc
     4381 gttttttagt ttccaggcgg tcttcgttga tatttcttat catcaagctc gtaatatttt
     4441 caacatttgg tttgatggct tgatcaacat atttaatcat gaataaaatt cgtaagacat
     4501 ttacgttaaa gttatctata tcagttggtc tttgaatatg agaattattt gtagcttgtg
     4561 taatcactcg gctaattgct gtatcaatcc aacgttctaa cgagtaataa aactgatcta
     4621 aagaaaccaa actggttgta tcattttcct tatttcgttc agcggcttct ttaaacattg
     4681 ctagtaatga acgttcacca gacgataagt ttgatccttg atagctgtga ttacgaatct
     4741 cggttagaat ttgccccaat aaattgaatt gatagggaat aaatggataa acttctgcgt
     4801 aattttcagc atcttggaag agctttaatt caggactatc aacaaagagt aatttatttt
     4861 tcaattctgt ttgaacagtt tcaaattgta aggctaaaga atcattggca aactcttttt
     4921 tcttcaaaat acgttcttta attacttcat cggcatttgc tgaagataaa ctcacagttg
     4981 tggcaaaacg atccttgatc ttagaaaaat cattatcaga attgttatca aagtttgtta
     5041 cgtgatcaat cgcttcctga cttgtcacta atacccaagc cttaccttca caaattcgac
     5101 ccaaatcttc cacaacggtt tgtaactgca aagtcaactc acgattaccg ccgatatatt
     5161 gtccgacctc atcgactaga aaggcaatat gatggtctgc ttctttggaa tcaagatagc
     5221 ttttaactag atttgcaaag tcatcaatgc ttattaaata atttcctgat gctttttcta
     5281 aaaaattatc aatagcggct tcactcataa aatcgatttt aagtgccgct tctttgatat
     5341 catcttggat ccaatcaaac tcatggcgct cttcttgcca ttttgcccca ttaatctctt
     5401 caaaagcagc tttgaatgca tcaaactttt cttctttaat taaccgacgt tcaaaatctg
     5461 ctagatgtgg aatcgtgctt aatccttgca tttcgttaaa tacctttaaa aaaacattca
     5521 cgattccgtt tttgtctttt ttaccacctg catcactttt tgaatcaata ttaaacagaa
     5581 taacatctgt atttatttgt gagcaccgtt ccatcgttgc caaagtcagt ggatctttga
     5641 ttttcccatc ttctttgaag taatcaatgg ctttcttgtc atttatttct cgatttgcga
     5701 gcaagtaaga aataattttt aagaaatgag atttacctga accaaagaac ccctgaatcc
     5761 aaacacccat tttatctgtt ggtgtattga tactccgttg gtaggcatca aaaattgttt
     5821 taaagtgttt ttgtagttct ttcgtaacca cgtattcttc taattcttgt tgaacatttt
     5881 catcctttgc ttgaccgacc ttaataactc cttgaatatt tcggtcaatt ggttttgcaa
     5941 aaatatcttt aattagcatt taatctccta ccttccatcc caactaaatt ctaaatgctc
     6001 gataataatt atcatcttta ttggtattaa gaattgtcaa acttaattca tcatattccc
     6061 ctggatacat catcacaact ggtacgcgat caaatacctg atgcatttta tttaaaatag
     6121 agtgcgctct aattaatgga tataattcgc caattcctgt caggaacaca actgattttt
     6181 ctggtgtatg ggcatccaca tattcaaaaa atacattttc ttcctcaggt aaatccattt
     6241 tcaataaacg accaatgctt tccactaatt tttgtaaacc acgtcgttct tccatcttaa
     6301 tcgctttttc agtgaaaccg cgtttttcta gatactctaa cataatcaca tagagattat
     6361 aaactttcac ttcataatta tcaccaacag atgttccaga tatatcatta atataatctc
     6421 ttacaattaa ctcgtctttc ggatcgtagt caaagatata atagcctact tcattaccta
     6481 aaccacgatt caataaaaaa tcttcttttt gaattacttc attcaacttt tccaaatgct
     6541 cttgaatcga taatgacatt ataaaattcc tcccagtgct agtacaatat ctttacgatt
     6601 cttgtcaact aaccattgaa tcaatcgttt atctaataat atcggagtca ttcgtccata
     6661 ttctttttcc cctctgacta atcctgtttc aattagattc gtttgataag cggcaataag
     6721 ccgtttaatc gtataatctt tccattttga aatatcttct gaacttctcc gcttctctgt
     6781 aaaaaaagaa cggtaatcaa ctggtgttaa ttgcaaattt cctttacgta gattttcagc
     6841 atatacctca gtcataaatt cattaaaaag atcatcaatc ataaggatgg aaatcaaatt
     6901 cactaacttt tgattatcta tatttaactg attgaaaagt tgcaatccag cttcatccag
     6961 ttgactaact ctccttttca cgttctgata gatttctttt tgacggttac tgctcactgc
     7021 aaaaaaaata ttttcatgtt catttttctc tttaatttct atatctgtat atccttctag
     7081 tcgtaattga atatataact tgaactctga aaaccaaaag cgtttagaaa ctagaccagc
     7141 agaatatttt ttattcaata gattgcctcc taatcatcta taattcaata agtaaacaag
     7201 tgttttttgc tcatcgttag cattcatttt ttagtatcta ctatacaata catatttatt
     7261 ata
//
LOCUS       DACBYO010000120         7125 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.120, whole genome shotgun sequence.
ACCESSION   DACBYO010000120 DACBYO010000000
VERSION     DACBYO010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.120"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..376
                     /locus_tag="IVD26_002650"
     CDS             <1..376
                     /locus_tag="IVD26_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP6080562.1"
                     /translation="INPDFIETVNYVTNFQREMRKVEAMTVLATQSPQEMVPENMSSD
                     NFSKLKKVFEFSSTKIFMRMDESILRHIEGLVGKSMTNSELESIPQQNQGDAVINFGS
                     KETIRVHFSPNKRQLKLFDGGK"
     gene            376..1581
                     /locus_tag="IVD26_002651"
     CDS             376..1581
                     /locus_tag="IVD26_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP6080563.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            1597..2241
                     /locus_tag="IVD26_002652"
     CDS             1597..2241
                     /locus_tag="IVD26_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080564.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            2252..3058
                     /locus_tag="IVD26_002653"
     CDS             2252..3058
                     /locus_tag="IVD26_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080565.1"
                     /translation="MSKKKGERQRFKKRKSYLQWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            3080..3310
                     /locus_tag="IVD26_002654"
     CDS             3080..3310
                     /locus_tag="IVD26_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080566.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            3856..4131
                     /locus_tag="IVD26_002655"
     CDS             3856..4131
                     /locus_tag="IVD26_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080567.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            4173..4595
                     /locus_tag="IVD26_002656"
     CDS             4173..4595
                     /locus_tag="IVD26_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080568.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            4614..6206
                     /locus_tag="IVD26_002657"
     CDS             4614..6206
                     /locus_tag="IVD26_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080569.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            6218..6553
                     /locus_tag="IVD26_002658"
     CDS             6218..6553
                     /locus_tag="IVD26_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080570.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            6700..6894
                     /locus_tag="IVD26_002659"
     CDS             6700..6894
                     /locus_tag="IVD26_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080571.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            6926..>7125
                     /locus_tag="IVD26_002660"
     CDS             6926..>7125
                     /locus_tag="IVD26_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080572.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKI"
BASE COUNT         2750 a         1076 c         1436 g         1863 t
ORIGIN      
        1 gattaatcca gattttattg aaacggtcaa ttatgtcaca aactttcaac gagaaatgcg
       61 taaagtagaa gcaatgactg ttttagctac acaatcccca caagaaatgg tgccagaaaa
      121 tatgtcttct gataacttct cgaaactgaa gaaagtcttt gaattttctt ctacgaagat
      181 ctttatgcgt atggatgaat ctattttacg tcatatagaa ggattagtgg gtaaatcaat
      241 gacgaactca gaattagaat ccattcctca acaaaatcaa ggagacgctg tgatcaattt
      301 tggctcaaaa gaaaccattc gtgttcattt tagtccgaac aaacgtcaat taaaattgtt
      361 tgatggagga aaataatgga aaaccaaaat gaaagtttaa tcaagcagta tgttaagcgt
      421 cgtgcaaagc ggcgcttatt tttgtggttg tttggtactt ctgcaggttt gattactatt
      481 ttgatcactg tgttcgtgac cctatttcta atacttgcgg cgggctcgat tgataattcg
      541 gattcagatt caagcagtgg tggcgaagct tttacaggag aatattcgga aggcttaccg
      601 atttataaag aaatcaaagg aagaggccct ttttctgatg agattgcgca atatgccgta
      661 ggtgcagcag tgaaatataa attattacca agtgtgatcc tttcgcaata cggttacgaa
      721 tcagcgtttg gtacatcggc gtccgcaaga aatgatctca actattttgg gattacttgg
      781 tttgatggtt gtctgtttcc taaaggaact gcacgaggaa ttggtggcat tgaaggtggc
      841 tggtacatga agtttcccaa ctcaaaagct gcattttcct attacggctt tatggtagcc
      901 acacaatcaa attttaatgc ttgtgtagga aataaaagcc ctggcgcaag cttattgatc
      961 ttaggacgag gcggttatgc cgctgcagga attacggaag atagtccgta ttatacaggt
     1021 tgtatgtcaa ttatcacttc taataaatta accgaatatg atgaattcgc catcaaacat
     1081 tggggtgaag gtggcaataa caacggcacg attactggtg aatggacgaa tccattccct
     1141 ggcagcagtt tagataaaag ttccttcagc ggtggtcaat tatttggaac gaatccaggc
     1201 ggtgaattcc gtccgaacgg cttccatgat ggattagatt ttggttcagt tgatcatcca
     1261 ggaagtgaga ttcatgcggt tcatggcgga aaagtcgtgt acgttggcaa tcctggtatt
     1321 tcaggtttgg gcgcgtgtgt gatcgtgatt aattacgatg gcttgaatat ggtgtatcaa
     1381 gaatttgcaa atagtacagg aaattctcga gtgaaagtag gcgatcaagt gaaagttggt
     1441 caagtaattg ggatacgaga tacagcacac ttgcatttag gatttactcg aatggattgg
     1501 cgtcaagcac aaggacatgc attcattgat gatggtacat ggatcgatcc gttaccattt
     1561 ttgaatagca gtaaaaaata gatcaggaga aaaaatatgg aaaataaaac gttaaaaatc
     1621 gtcttaacag ctgcaattag cgttagttta atcggcaata ttgcgttgtt ttggcagctg
     1681 aaagaggaac aagcagcaaa tacctataaa attgaagaag tggctaaaaa cgcgtctgag
     1741 aagctcaaaa aaaattcctc tgaggcacag gcgaagatcg acaagttaaa tcaaaccatc
     1801 aatgagaaaa accaagaaat cgatcagctg aagcaacaag atggcacaaa agcaaaagag
     1861 gaagtaactg aagcacaaag aaagacggca gaagagttcg gtcaattggc cattgataaa
     1921 tcattaagca gaaatgaatt aacggaaaaa ctaaaagatg tcgcaaccca agaagtgatc
     1981 gacaaattaa gtcctacaga cgatgatcac caacatgatg attacggaag ttactccttt
     2041 acattaggtg acgtgcaaac ttacgctcaa acaagcagtg taaaagagga acaaaatttt
     2101 gtcgtatttg ttgattatac aatcggcaat ccgcaattca aagatgtcaa accacaaaaa
     2161 ataaaaggtg gattaactgt cactgaaaaa caagtagatg gtcaatggaa agtcatagac
     2221 tttagttatt tcactcgtta ggaggaagaa aatgagtaag aaaaaaggag aaagacaacg
     2281 tttcaaaaaa cgaaaaagtt atcttcaatg gctgggaatc tttatgattc tcggcttttt
     2341 gattcttgct agtccgattt atacgaatca gaaggtagat ataccagatg aggtaagcac
     2401 gaacgccttt ttaaacacga aagagctgac aatggtttca aaagaaaaag gagcgaacca
     2461 gcaattagtt tttgaatttg cgatcgatga tgaagatcaa agcttgttaa aagaactggc
     2521 taatcttaat tatcgcgtag aagtaaagac agctaaaggg gattatcaag caatacgagc
     2581 caaagtgatc aaggtgtctg atgattattt tgcagtgaag ctaacgcatg taccagaaga
     2641 atatatcgcc atgcgtttaa ccattattcc tgaaaaaatt gatccaaaag tggatatgca
     2701 agaaccacaa gatctgattt attacgtgca cgaagataag gttaaagatc aagtgaaaga
     2761 tgaagattat gaacaacacg cgatcaatta caaagtgaaa ggatacaaga aagaacaaaa
     2821 agcagctcaa aaacaaatgg aatctttcca agcaaccatt gatttgaatg aagaattagt
     2881 gaagaagcta aaagatcaat tgccttatca agtcgcagat gatcaggaaa atactgaaaa
     2941 caagattaat agctaccagc aagaaattga aacatcgaaa acgcaactga aagatcaaga
     3001 agagatcatt caaaaacttc aagaaaaaat tgatcgtatg acaaaagaaa agatttagaa
     3061 ggacaggtgg agtgaaaaaa tgaagcgaac aaacttggct gacaaagata ctttcgctga
     3121 gcagaaagta ttgattaaag cctatctcaa agttgtaaaa gctaaagaaa tatgtcgaga
     3181 agtgaattta tctaacacaa caatatctga gttgaagaat ggtcgaaaga atttagatac
     3241 tttaaaattc agatcatttg aagctctata tgtagctgct aaaaaatatt ttacagctga
     3301 taacaaataa aaaacaggag tattttatgt gaaaaaagta tataaaaaat gcttatgaat
     3361 aagctatatc accttaacca tttgttaatg agatgggaga aaacattaac cacgattcta
     3421 acgcaaacat caagcacata aaacatttaa cactcctcct ttctggctga agatttcaac
     3481 caaacaggaa gacagcgtat caattatagc atacactttt tcttaaattc atttttcata
     3541 tgacaaaata tttccttcta atcgacaaag ttagaaggat tttttattgt ctaaatacac
     3601 aaataacctt aatttttaaa gagcataagg aaacgtgata tcactttctc acgaaaggtg
     3661 ttaggtaggc tgtgcctacc acgtttctaa gaaagataaa tgatatcaaa attttggatt
     3721 tgtgtgtaga tttgtgggta ggatgaaagc gaatgtgggc agtaaaataa gcgtttgtgt
     3781 gtagcaaaat caaaaaatgt gtagggatat gtgtagctac acatatccct acacataata
     3841 aatttggagg aaaatatgga cttattaatt agaaatattg aagaaaagta tattaataaa
     3901 attgacaaac gttgtgaaga acttacggtc aagactggca aaaaatggag tcgaaatcaa
     3961 tacctaaaag ttttgatcga aaatgatttt gatcacgctc ttctgaatta taaaaaagac
     4021 caatttgatc ggttgttaga aaaatttgtg gatattcaaa cttataatac gaaaacttta
     4081 gaagaatata ttgcaacaaa taatcaatta attggtttgt taattgaata ataaaaatag
     4141 tattgtgaat ttataaaagg aggaaatcaa ttttggcaaa agcaacaaga aaacatgtat
     4201 atctttacga tatgcatatc gaagtacttg atgaaataat ttctactcat gaagatatat
     4261 ctaattatag tgaagcagtc agacatttgt gtatgatgta tgatccaaaa atcgaagaaa
     4321 aaataaatcc aattcaaatt aaattgaatg caatgggaaa agaaatttct attttaaccg
     4381 aaatggtttc agagtttgcg gatcttcatt tgaaagatac aggaatacta attggtacaa
     4441 attcaactgt ttatcaagaa gcagaagaac gtgtggaagg aaaaattaaa tccaatcaaa
     4501 ccaaaaaata ttcttctaag ttaaagaaac cagtgaatga atctgttcat accagagtag
     4561 atccatttga tccaacgaag attctaaaaa gataaaagta gaaggagaac gtgatgaata
     4621 aatcgcctgc agttattctt acttgtcaat ttaccttgcc caataaaaaa tctttttcaa
     4681 catacattga ttatatgaca agagaaaaag cactggaaga aatggaacga cgtacgcccg
     4741 aagaagaaca ggaactgcaa cgaatcaaga atgctttaga ggatttttat attcctgaag
     4801 gagaaacttt ttcggaaagt aagacggata aagaattcag tgaaacgtcg aatgaagctc
     4861 aatcgttgat ggaacatgga atcaattttg acaagttaga ggaacaagat tttaccaaat
     4921 atctttctta tatgacccgt cactatgcgt tagaacaaaa gaaagaactg acgcaaaggg
     4981 aacaaaaaga ataccaacgg ttgaaccaag caatgaaaaa atatcaaaca gagccacata
     5041 aaaaagcttc aggaaatctt cctggagttt tttctatggc ttcagacgaa gtgaaaggaa
     5101 gtgatctgaa ggagatcaaa caaatcttcc aaagaggaca acaaaaaggc tcaatcattt
     5161 atcaagatgt tatctctcac gacaattcgt atcttgaaaa aatgggcttg tacgatccca
     5221 aaacagatac cttagatgaa gaaggtttga aagcagctgg aagaaaaatg atggagacat
     5281 tattcgagaa agaacaattg aatgaaacag gttactggat ggcaacgatt caccgtaaca
     5341 ctaagcatat ccatattcat tttgcagttg ttgaaaaaga aaatacgcgt aaaccgtata
     5401 ctgagattga aaatggtgtg agttatatcg taccgaaggg gaagagaaga caagcaacat
     5461 tagacgcaat gaaaaccaat tatgtacatg agttagaacg tttctcttat gaaaaggatc
     5521 gaatgatcgg tatggagaaa cgaaatttat tgacacgaaa aagtgatttg cgtaacacct
     5581 taacaaaagt agtaaaagaa ccagcacgtt acgatcgaca cgccatgaac ttattaaatg
     5641 aagtatataa aaccctacct gaaaaacgtt cggaatggaa ttatggagat gaaaatcgaa
     5701 ccaagctttc accatttaca aggggaaaac ttgatgagtt aaccaaatat gttttaacaa
     5761 aagaacctgg atatcaagaa tatatacaga tttcaaaagc attgaaagaa gaagccaaaa
     5821 gcctttatgg ggaaagcaaa agagaaacaa agaatgcaga aaaaaacgcc ctctttgatt
     5881 taaaaaagcg cacaggaaat gcgattttaa cagaactgaa gagacaggat agtcaaataa
     5941 aaccattaat agaaagtgtc aatcagatgc aatctattta caatgaacga tcctttcgaa
     6001 cactcaaaca gttgccaaca aatgaataca agtatagtta tcaagaattc gtaaagcgta
     6061 ggaaacaatt ccaacaaaga gttgtcacgc agcgaagctt gcgtcaatta aatcgaacaa
     6121 ttaatgcaca tgaagaaaaa taccacgcaa gtaaagcata tgaagagcaa cagcgaagaa
     6181 tccaaatgga acaagaaaga caataggagg aagagaaatg aaacaatatt tagatcaatg
     6241 gaaagtcata gaaggatcac taaaagaaga acgaatcgaa caacttcctg attgtttaga
     6301 aaaagagcat ttgtttcaga taagcgaaat gttgagaaac gaacagtttg atccaaatca
     6361 atttttagtt gttgagtacc cagctactgg tgtgtattgt tgtaatcatg tgaagggtga
     6421 aaaatatttt attattcaag aatacgaagg taagttagcg ccttattata ctacttggga
     6481 aataaatgaa gagggaatca ataatttccc atgtgaaagc attgaagagt ctatttctct
     6541 cacggaatgt taaataaata gagacgtaaa agagtcctga acgtgattgt ccaggactct
     6601 ttttcaatga attgttttcc gccaattcac tgagtggtgc gattcaattt tattatatca
     6661 aaagaaagtg agattccaaa gtgaagggag gaagaagaaa tgactcagac aacgattggt
     6721 gttgtggttg aaaaaagcag ggataatctc gtttttgtga cagaaattca aacaggtaga
     6781 gcttttgtag tcacagacaa agctgcaaaa gcgtatcaaa atggcaatat tttaacgtta
     6841 aatctgacta cgaagatgtt cgttgatgca gtagaaaatt atccatttgt ttagacaaac
     6901 gatattttac aaggaggaaa cggacatggc agaagaaaaa gaaccactag ataatagtcg
     6961 tttgggaaag tccaaaagaa aattagtacg gttgcaaaac gaattaaata atcaatttca
     7021 aaagctattt gatcaccaaa aattgacaaa tgggcaacca atgaatgaca aacgaaatgg
     7081 tcgttcatgg tttaaccagc aagaaaaaat agaaaataaa ataca
//
LOCUS       DACBYO010000121         6989 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.121, whole genome shotgun sequence.
ACCESSION   DACBYO010000121 DACBYO010000000
VERSION     DACBYO010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.121"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..1086)
                     /locus_tag="IVD26_002661"
     CDS             complement(<1..1086)
                     /locus_tag="IVD26_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP6080573.1"
                     /translation="MARKKLKICMLGHKRIPSREGGIEIVVEELATRMVALGHEVTCY
                     NRSGHHVSGKEFDQHKNKEYKGVKLKTIFTLNIKGIAAMSSSVFGGIRAAFGKYDIVH
                     FHAEGPCAMLWLPKLFGKRCVATIHGLDHQREKWNKLASTYIMLGEKCAVKFADEIIV
                     LSESVQNYFEDIYGRKTRFIPNGVKKIEIKSAGLITEKYGLTKDSYILFLGRLVPEKG
                     IRYLIEAFKDVQTDKKLIIAGGSSDTDEFANELKELAKGDERIIFTGFVQGQELEELY
                     SNAYIYTLPSDLEGMPLSLLEAMSYGNCCIVSNISECTEVVEDKAMIFKKSDVSDLKI
                     RLEEACNQSEMVKVLKNQATEFICSKYN"
     gene            complement(1118..2569)
                     /locus_tag="IVD26_002662"
     CDS             complement(1118..2569)
                     /locus_tag="IVD26_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP6080574.1"
                     /translation="MYRKNSSGWSKHIDFILLDLFCVQLAFYISYVMRQGDWNPYVIP
                     IYRHMAIFIELENLTIIFLFEAYKNVLKRGYYKEAVASIKQSFMLLLVCSLYLITMQD
                     GNDYSRVSLFIMGVVYGLLTYIIRILWKGLLHHRMKNGEDVSLVIVTSQKIAKNVVRN
                     LKEKNYGMYKLSGVIVVDRDMYGTTIGGVPVVANADNAAEYLLQNWVDEVFINVDESV
                     PYPKELIARCSEMGLAVHMNLTKVSDSTRGKQFIGRVGDYTVITSSINVMTMRQAFIK
                     RTIDILAGIIGCIATGVIFIFVAPVIYIKSPGPIFFAQERIGQNGKTFKMYKFRSMYM
                     DAEERKAELMKENKMSNNLMFKMDFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FYNVLMGKMSLVGFRPCLKSEYEKYDFHHRARIAMKPGITGMWQVSGRSDITDFEEVV
                     KLDAEYIRNWSMGLDFRILFRTVKTVLHRNGSM"
     gene            complement(2613..3377)
                     /locus_tag="IVD26_002663"
     CDS             complement(2613..3377)
                     /locus_tag="IVD26_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAP6080575.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKIPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKEFG
                     KEKVVQMKQVAKDLINGDEINYPIYEEVKKKKFGLF"
     gene            complement(3405..4103)
                     /locus_tag="IVD26_002664"
     CDS             complement(3405..4103)
                     /locus_tag="IVD26_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAP6080576.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(4115..4894)
                     /locus_tag="IVD26_002665"
     CDS             complement(4115..4894)
                     /locus_tag="IVD26_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAP6080577.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAQTQPKATNDKTAPSRRSRSRV"
     gene            complement(4910..5854)
                     /locus_tag="IVD26_002666"
     CDS             complement(4910..5854)
                     /locus_tag="IVD26_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6080578.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(5900..6679)
                     /locus_tag="IVD26_002667"
     CDS             complement(5900..6679)
                     /locus_tag="IVD26_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080579.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADIQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKISAAYATKAQTVAEQMGYSNISY"
BASE COUNT         1940 a         1486 c         1096 g         2467 t
ORIGIN      
        1 attatattta ctacaaataa actcagtagc ttgattcttc aaaactttaa ccatttccga
       61 ttgattgcat gcctcttcta atcttatctt taaatcactt acatccgatt tcttaaaaat
      121 catagccttg tcttctacta cttccgtaca ctctgagata tttgaaacta tacaacagtt
      181 cccataactc attgcttcta acaaacttaa tggcattcct tctaaatcac ttggaagtgt
      241 atagatatac gcattactat ataattcttc taattcctgt ccttgtacaa atccagtaaa
      301 tataattcgc tcatcacctt ttgctaattc ctttagttca tttgcaaatt catctgtatc
      361 agagcttcct ccggctatta taagtttttt atctgtctga acatctttaa atgcctcaat
      421 tagataccga attccttttt cgggaaccaa tcgccccaaa aacaaaatat aagaatcttt
      481 tgttaatcca tacttttctg taatcaatcc tgctgatttt atttcaattt ttttaacgcc
      541 atttggtata aaccttgttt ttcttccata tatatcttca aaataatttt ggacgctttc
      601 actaagtaca attatttcat ctgcaaattt tacagcacac ttttccccta acatgatgta
      661 tgtactagca agcttgttcc atttttctct ttgatgatct agaccatgaa ttgttgcaac
      721 acatcttttc ccaaaaagtt ttggcaacca caacatagca catggtcctt ctgcatgaaa
      781 atgaacaata tcatattttc cgaatgctgc tctaattcca ccaaatactg aagaactcat
      841 tgctgcaatt ccttttatat ttaatgtaaa aatagtcttt aattttacac ctttatattc
      901 tttattttta tgctggtcaa attcctttcc gctaacatga tgaccacttc gattatagca
      961 agtcacttca tgcccaagtg caaccattcg cgttgccaat tcttctacca ctatctcaat
     1021 tccaccttct cttgatggaa ttcttttatg acctagcata cagattttta atttttttct
     1081 tgccatcacg ttttactcct tctatagtat ctttatctta catggaaccg tttctatgaa
     1141 gcacagtttt gactgtccta aacaaaattc taaaatctaa tcccatactc caattcctga
     1201 tatattctgc atcaagtttt acaacctctt cgaagtctgt gatatcactt ctaccactca
     1261 cctgccacat tccagtaatc ccaggtttca tcgcaattct cgcacgatga tgaaaatcat
     1321 acttctcata ttctgacttc aagcaaggtc taaaccccac caggctcatt tttcccatta
     1381 ggacattata aaattgtgga aactcatcca atgatgtaga tcgaataaat tgtccaattc
     1441 ctgtcttctt tgttccatca ggaagtattt tattgccaat gattcttggg tcaaaatcca
     1501 tcttaaacat gagattatta ctcatcttat tttctttcat caactctgct ttgcgttctt
     1561 ctgcatccat atacatacta cggaacttat acatcttaaa tgtcttacca ttttgaccaa
     1621 tacgttcttg tgcaaagaaa atcggccctg gtgatttgat gtaaataact ggtgctacga
     1681 agataaaaat aacacctgtt gcaatacatc caataattcc agcaagaatg tcaatcgttc
     1741 tctttataaa tgcttgcctc atcgtcataa cattaatact agatgtaata acagtataat
     1801 caccaactcg gccaataaat tgttttccac gtgtactatc agacactttt gtaagattca
     1861 tatgtacagc aagtcccatt tccgaacatc tggcgattaa ttctttggga tatggaacac
     1921 tttcgtcaac attgatgaat acttcatcta cccaattctg taaaagatat tccgctgcat
     1981 tatcagcatt tgcaactact gggacacctc cgatggtagt tccatacata tctctgtcta
     2041 ctacaatcac accactaagt ttatacatgc cataattctt ctctttaaga ttacgaacta
     2101 cattttttgc aatcttttga gatgttacaa taactaacga tacatcttca ccgtttttca
     2161 tgcggtgatg caacaaccct ttccaaagta tacgaattat atatgttaat aatccataca
     2221 ccacccccat tataaataaa gaaactctgg aataatcatt tccatcctgc attgtaataa
     2281 ggtataaact gcacacaagt aacagcataa aagattgctt tatagaagct acagcctctt
     2341 tataatatcc tctttttaaa acatttttat atgcctcaaa taaaaatata atcgtaagat
     2401 tctcaagttc tataaaaatt gccatgtggc gataaatagg aatcacatac ggattccagt
     2461 caccctgtcg cattacatat gatatataaa aagcaagctg gacacaaaat aagtctaata
     2521 aaataaaatc aatatgttta gaccaaccac ttgagttttt tctatacatc tctcactctc
     2581 tcctcatttc ctttttatct acgaataaag aactaaaata aaccaaactt cttctttttt
     2641 acctcttcat agattggata attgatctca tccccgttga tcagatcctt tgcgacttgt
     2701 ttcatctgta ctactttttc cttaccaaac tccttggcaa tctgctcata gcactctttt
     2761 aagtaaaagg tgcgcttaga gaccccgtgt gcatcagaag cagccatctg cacgagatta
     2821 tgtttgacca ttgttttggc tgttttctgg atatctttgc caaatacacc aacataactt
     2881 ggcgcagtaa gttgggccaa acatcccata tctaggaacg gaagcaaatg atttgggtct
     2941 tctcgaaaat gcgcgttgcg ttctggatgg acgatcactg gtatctttcc tagttctaac
     3001 aactcaaaaa aaagccgttc tgcatataac ggcacttcca gtgtcggaaa ttcgatcaga
     3061 agatatgtat catctaaatc tgtaaataaa atttcatctc ggtggatgtc ttcgatgagc
     3121 gttccggtaa tacgtacttc ttgtccttcc aataacgtca aaggcaactg tcttttctct
     3181 aattcggctt gtaacgaagc gactagagaa atgacttgtg atttttcatt gctgtatttt
     3241 ccattattgt ggtgtggtgt gcataaaata tgcgtaatgc cttgctgaat cgctttttca
     3301 gccattgcaa tacttgcttc taagttttct gccccgtcat cgattcctgg taggatatgg
     3361 caatgtagat cgatcatttc tcttgtctcc tctcttctta ttccttaatt tccgtagtaa
     3421 taaccagcat ctttgctgtg ttctgctccg ttgtatacga cacctaagac tcgtgcttgt
     3481 accatatcta acagttcttt tgctttagtc aatgattctt ttcgtgacgt attttcccgt
     3541 acgaccaata aggtgccatc cgtttttgaa gacatgatct gtgcatctgt tacggcaacg
     3601 actggcggca tgtcgaagat cactacatca aatagttgtc ttgcttctgc taaaatctga
     3661 tccattcttg gcgaacttag tagttctgat ggatttggtg gtttaggtcc acttggcaga
     3721 atcgacaaat tgtcgactgg tgttcgttgg atctcatctg ctacacttcc tgatgaacta
     3781 agaacagtac ttaatccgct tgcgttgttc aacttgaacg ttttatagat gacgggctta
     3841 cgtaagtctg catcgactag cagcacccgt tgaccagatt tggcaaaaac aacggcaatg
     3901 tttgctgcag tggtcgattt cccttctcca ggtcctgatg aagtcacaac aatcgttttg
     3961 atttgctgac cagctgcgga ggcaaactgg atattcgtcc gaatcgtacg atattgttca
     4021 gcgattggtg aagagggatt ggtgagtgtg accaaactga ctgcatgagt ttgggctgct
     4081 ttttgtttct gtgttcgtgc cattttcttt cctcctagac tcttgagcgg cttctgcgtg
     4141 atggcgctgt tttatcgttt gtagcttttg gttgtgtctg agctggtcct tttttacgga
     4201 taccagcatt caattctttc gctgacattt ctggaactgt tcctaagatt gggaatccta
     4261 atgtatctgt cacatatttt tcatctttca ctgtccgatc gagtaattcc aataagaatg
     4321 ccagacctac acctaccatc attcctaaca ttaagccagt cattaaattc aatttattat
     4381 ttggcgaaac aggtgtcgta ttggcaactg cacctgaaat gatcgagatt ttatcaacat
     4441 tcatcacatc ttttgcgttc tcttggaaaa cttgtgaagt tgtgttagcg atctgttgag
     4501 cagccactgc attcgtactt attgcctgaa tcgagaacat ttgtgaattt tctgcctgat
     4561 taactgagat ggcatctttg atttgttcag cagtcatttt cacattgtct tctgtttcta
     4621 aacgatcttt gacttcattg agcactaaat cactgacgat catatcttta tacgtattga
     4681 tcatttgcag gttcgtattg acatcattga catttgcagt gtctgattgt ggcagtgtca
     4741 cgatcaattg tgcttgtgaa ctgtattttg gtgtcaagat gaaaaatgtt acgattcctg
     4801 agatggccaa gccagcaaac attgagatga tgattattac caagtgtttg cgtaatgttt
     4861 caaaaatttc tttcaagctg attgtctctt ccattttttc tccactttcc tatttattct
     4921 ctagattcat ttgatctttt aattcttttt tcacacgatc aagttcttga tcactgactt
     4981 tttgatagga gatattatct tgcatgaagc cttctccttg cagctgatct tgcttaatcg
     5041 taccaaatgc ctcccgataa tctaaagcaa tttttttcat ttcatcaaag ttcatgtctg
     5101 ttttcatatt cgactctaga gcattcaaaa cggattgata gttgctgaca ccgtttagac
     5161 tcaatacttt tttcgctacg ccttctacga tctttctttg gcgcccttgt ctaccgtaat
     5221 caccatttgg gtcttcataa cgcatacgag aataagataa tgcctgatcc ccgttcaatg
     5281 taattttacc gattggaaag tcatagccat cttgtgagaa agtgaggtca ttattgactt
     5341 cgataccacc aactgcatca acgagttcct ttagcccttt catattgata gagacatagt
     5401 gatcgattgg gatgtctaca tatttttgta cggtatccat cgccatggca gctccgccga
     5461 atgcgtaagc gtggttgatc ttgtcttttg tgtcacgacc tacgatgtcg acatacgtat
     5521 cacgaggaat gctgacgatc gttgtctgtt tgtcttcagg actgactgtg gcaaccatca
     5581 tcgtatctga tcttccttga tcgacccgac ctaaatctcc agtatcaatc cccatcaata
     5641 gaacagagaa agattcttgt ttgtccagat caactggttt cgttcgttct ccttgggttc
     5701 gttccactga ttcgtaagtt ttctcaatag aatgtgagag atccagatat aattttgctc
     5761 ctactcctac aattgctaat actaatacga taagaactgc taaaataatc agaaatattt
     5821 ttttccctct tgattttctt cttcgtcttg ccatagtttc ctccgtttgc taaccttgct
     5881 tgaatcaacg ttttaactgt caatagctta tattgctata gcccatttgc tcagcaacag
     5941 tttgtgcttt tgttgcgtat gctgcgctta ttttttcatt ccggatctgc tctatttgac
     6001 tgagcaccgt caaatattga tcgtaagtag cggtggcagt cacttgacca tcctttaaca
     6061 tcgtatcgaa taactgatct agttgcgtga cttgcgcgat ctgaatatca gcgaatccta
     6121 gatattgcat aacaaccgtt ttccaaggac tatctttaaa aaagctcata ttttcacgta
     6181 cacgagcgac atctgcactt gtcacctttt ctttgatgat gacatcgtct acagcttgct
     6241 gccagtttga tacattttta gtaaataaat cgttgacagc tgtctggatc ttcagttttg
     6301 attctgcact atctaactgt gtcacgattg ctttcttctc atcttggatt gcaacagctt
     6361 ctttaggcaa ttctgattct ttgatgtcgt aatcatctgc tgaaagtttg acagaggata
     6421 gcttatttga caaacttgtg attgtttctt ctgttatttc agggtttaga aaaatttttt
     6481 cttttgtact atacagcttg tctacttctt ttgataaaga agtcaaggtg tctttttgat
     6541 tggtgatggc agattctgca taattgatcc gttgctgatg ttgccgctga ttattgatat
     6601 ggtatccaaa caaacagatc gcaatagcac ctgcacctac cgccacagca gtcaatgact
     6661 tgacgaatgg cttttccata gattcactcc taagtattga tgatagataa attaagatat
     6721 aattcactta cataaaaatg acagcttttt atttaaaaaa acataattaa actaatatat
     6781 tcacagaaat atttgtaaac aagttttccc tatataatca taccacaaac tgttttcttg
     6841 actagggcaa tttacgattt aaaagtaaat aaaacattaa taagataaaa attaatcgat
     6901 ttcattttta tttccataat tttcataggt gtttttaaaa gttacacaaa aaatagaata
     6961 acaaaaaaat taacattgaa ttaataata
//
LOCUS       DACBYO010000122         6644 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.122, whole genome shotgun sequence.
ACCESSION   DACBYO010000122 DACBYO010000000
VERSION     DACBYO010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.122"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(1..859)
                     /locus_tag="IVD26_002668"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="IVD26_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="IVD26_002669"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="IVD26_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAP6080580.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="IVD26_002670"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="IVD26_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="IVD26_002671"
     CDS             complement(2143..2373)
                     /locus_tag="IVD26_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HAP6080581.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="IVD26_002672"
     CDS             complement(2603..3421)
                     /locus_tag="IVD26_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP6080582.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="IVD26_002673"
     CDS             3582..4271
                     /locus_tag="IVD26_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAP6080583.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="IVD26_002674"
     CDS             4285..5787
                     /locus_tag="IVD26_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6080584.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="IVD26_002675"
     CDS             5800..6276
                     /locus_tag="IVD26_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP6080585.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="IVD26_002676"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="IVD26_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2174 a         1032 c         1203 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttattatcca aaaataataa aaaattggag cgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt catgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DACBYO010000123         6540 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.123, whole genome shotgun sequence.
ACCESSION   DACBYO010000123 DACBYO010000000
VERSION     DACBYO010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6540
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.123"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..262)
                     /locus_tag="IVD26_002677"
     CDS             complement(<1..262)
                     /locus_tag="IVD26_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HAP6080586.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMA"
     gene            complement(346..1773)
                     /gene="uxaC"
                     /locus_tag="IVD26_002678"
     CDS             complement(346..1773)
                     /gene="uxaC"
                     /locus_tag="IVD26_002678"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAP6080587.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(1847..2926)
                     /gene="uxuA"
                     /locus_tag="IVD26_002679"
     CDS             complement(1847..2926)
                     /gene="uxuA"
                     /locus_tag="IVD26_002679"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP6080588.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPACEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(2929..4560)
                     /locus_tag="IVD26_002680"
     CDS             complement(2929..4560)
                     /locus_tag="IVD26_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAP6080589.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            4864..5535
                     /locus_tag="IVD26_002681"
     CDS             4864..5535
                     /locus_tag="IVD26_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6080590.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(6260..6540)
                     /locus_tag="IVD26_002682"
                     /pseudo
     CDS             complement(6260..6540)
                     /locus_tag="IVD26_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2104 a         1262 c          890 g         2284 t
ORIGIN      
        1 cagccataat tgcgatacga gcagtaaacg catctaaaac cgtaccggct ccgattatta
       61 catctttttg atcagcatat tttttagcaa tttctttgat tatttcttca gcattaggaa
      121 ctgtaaaagt tagttcaatc cctttaattc cacccgcaat aattgaattt attgctttaa
      181 tggcctcatc cttatttttc ccacgtacaa ccgcaatgac tccagccgct tctaacttac
      241 ttaaaatttc tacttttttc atatctatct ccttccttta tggatacata ctttgtctag
      301 ctgtactaac ttacaaagaa taaatttaag cttttatttc aagtattatt ttctacttcc
      361 gatttcaaaa aaattaaaat aattatacgc attacgataa caaatattct ccactatctg
      421 actaagatac atttcatcat ctggaattcg gcctgcttta acccactcgc ttagtaattg
      481 acataatact cgacgaaaat actcatggcg aggatagctt agaaaacttc gagaatcagt
      541 caacatacct gtaaaattcg acaacaaact ttgttgtgcc atcgtagtca actgttgacg
      601 cattccttca gctgtatcat tgaaccacca agcacatccc aattggattt tttgaatcat
      661 acccccttgg aagctttgca ttgctgttgc tagtggaagc caatcagttg gatttaatga
      721 atataaaatt gtttttggta agcacccact cttttcagcg gtatcgaaca atgctacaac
      781 attttgtgtc aaactagctt gatcccccat cgaatcacca ccgacatcta ctccaatttg
      841 ttcctttaat atacttgaat tatttcttaa agcatttaaa tgcatttgca tcgtccaacc
      901 atatcttgta tactcagaca tcaaatgtaa ttgaatacct gtaacaaatt gtgcaatttc
      961 tgataaatgg aaatccgttt ttcctgctaa agcttttatt aacagattgt cgagtatttt
     1021 ttcatctgct atttcataaa aataagtatt caaaccgtga tctgctaatc gacagccaat
     1081 ttgatgaaaa tgatccactc gttggctcaa tgcttgcttc aacccattaa agtctttgat
     1141 tggtatagcc gctgtttgac taagttttaa aatatagttc gaaaagcctg atgatttgat
     1201 actccagacc ttatctggac ggaaagtagg taataccttg aaagaattat cctgtttaga
     1261 aagctcagta tgataccaca agtcatctgt aggatcatcc gttgtacaga tggctttcac
     1321 atccatcatc tccaacaatt ctttcgggcg ataggaatcc gtttgaattt tttcgttagc
     1381 acgtcgccaa atttctggtg cattcttctc agaaattgtc aaatcaatat caaagtaacg
     1441 ttgtaattcc aaatgagacc attcaaaaat aggattacct ggcgccttct ccactgtttt
     1501 tacaaaagct aaaaattttt cataatcatc acctggacca ctgatcaact cttcttctat
     1561 accattagct cgcatcaatc gccatttata atgatctcca gctcctttat catttaacca
     1621 tacctgagtc aaattcttgt attgcttatt ttctagcaaa tatgctgggt ctaaatgaca
     1681 atgatagtcg ataattggtt ggtgttttgc aaatttatga aaaagtcttt tagctatttc
     1741 attctctaat aaaaagttct tatctaaaaa catatttaaa cactcctttc cttccgttag
     1801 tttttagaag agaaaatttt tcctctaaat aaactccctt atataattat ttactcgccc
     1861 ccttttcaag cgcttcccaa ataccattta aataaactgc acctagagct cggtcatata
     1921 atccataacc aggtctaccg gtttctcccc aaatcatccg accatgatct ggacgaatat
     1981 agccattaaa tccattatcg tacattgttt ttaatatctt atacatatct agagaaccat
     2041 attctgattt atgcggcgct tcgtaaaaat cgagtccatt gtcacttaaa tatttgatat
     2101 tacgaacatg tgcaaaagga atccgatccc gttgacaaaa ttcagataga atttcataga
     2161 catcattatc tggtcgttct gcaatacttc cagtacataa tgtaatacca ttagaaggag
     2221 aatccactac attacacaac caatctaaat cgtcacgatt tttaacaata cgaggtaatc
     2281 cgaaaatgga atatggtgga tcatctgggt gaactgccat tttaatccca acttcttcac
     2341 atgccgggat aattgctttg agaaaatatg caaagttctc tcgtaatttc tcttcatcaa
     2401 cttctttata ggcttctaat aattgcttaa tttgtgataa ccgatgaggt tcccaacccg
     2461 gcaattcaaa attattagta gaattttcta cttctctaat aatttcctcc ggatcagtag
     2521 ggatattttt tgaaatatag gctaacgtag aagacccatc atctaaacga taatccaaat
     2581 ccgattttac ccaatcaaat actggcataa aattataaca gataacctca atcccaaatt
     2641 ctgccaaatt gcgaatcgtc tgtttataat tctcaatgta ttgatctcgt gttggtaaac
     2701 caattttgat atcatcatga acattaacac tctcaataac tttcaaggta agtccattgg
     2761 cttcgacttc atcttttaaa gatttaattc gttctctcgg ccaaacctct ccggctggta
     2821 tatccattaa tgttccaaca attcctttca ttgctgggat ctgacgaatt tcttgtagtg
     2881 agattttttc ttcatttgcc ccataccatc taaaagtcat ttccatagtt actttcctcc
     2941 aacttctgtt atatatttat tgattgtttt acgaactgct tgaggaccta ctagcatttc
     3001 gcaaaagatt ttttcagttt tctttcctac cccaacttga tataaatcta aaccaaagat
     3061 ttctttattt tctaaaattt cctgtaccgc acaatgaatc tttgaaggat cttgttcacc
     3121 taatttcaat actgataatt tatcctgcaa ctctaccaat aacggatcag gacttggcac
     3181 aaaattttcc ccttgatcat cgactgccag taaataacgt aaccaagcag caatagcgat
     3241 aggaataaat gttagatttt ctgcatttcc gtctttttcg acatactttt taattgtttc
     3301 accatagcga atcgctactt tttgagaagt atctgttgca attcgttgtg gtgtatctgg
     3361 aatataggga ttaggcaaac gtttattaat tacttcatca ataaattgtt ttggatcaat
     3421 aatgcctgga ttttcaacta ctggtaaacc ttctaaataa cctattcctt tgattaaacc
     3481 aaccaaatca tcatcctgca tctctgctga aattgattga tatcctagca gacaacctgt
     3541 tactgccaaa gcagtatgaa gtggattcaa gcttgtcgta accttcatga tgtctgcttt
     3601 atcaaccgtc tctctatctg tcataatcac accagccttt tccaatttag gccggccatt
     3661 tggaaaacta tcttcaataa ctaaataatg aactacctca gtattagtga aagcagcaat
     3721 attggtatgt ttttttgtgt gaatgatatc taaatcctcg agccccatca tcaatagatc
     3781 ttcctttaca ttctctgaag gatttggcgt aattcgatca atcatactcc aaggaaaagt
     3841 cactttttct ttatccttta aataagcaat aaatttttca gaaacatatc cttctttttg
     3901 ccaagcttct gcaatcgtaa aaatactatc ttgaaaacgt tgaccattct gtgagaaatt
     3961 atcagtagaa accatcgcaa tcggcaactc tccagcatta aatctgctat ataacaagga
     4021 tgttacaata ctcatcgtat gttgaggatt gctaggtcca gatttgatat cagctttgac
     4081 taccgaaaag aattgccctt tagaatcttt taaactgtaa cctttttcag taatagtaaa
     4141 cgttgtaaac tgtaatttag gatcttcaaa atatttaacc actctttgat agtccgctat
     4201 attcttcgga ttgcaatata aactatcagc cgttactgcc aaaagtcttt ttttgagttc
     4261 accatctcca ctcataacaa tttccaaaat gtcattgtta tagtcatgat aagctttttc
     4321 cactacttct tcatcaaatg tttcacacac aactactcct gtttctaatt cattttgatc
     4381 tgctaagcat tgagcaattt ctgcatgaaa tcctcgataa agatttcctc caccaaaatg
     4441 aagccatact ggatgttgct ggccttcttg cttaacttct ttgacatcaa aacacggcag
     4501 tagaatctgc atttcattga attcttcgat agaattttgc caatttttaa tcgaaaccat
     4561 aattaacctc ctcaaactga tatgttagtt ttgatacatt ttatatttta aaacccattg
     4621 taaccgttgt caatataaaa agggaataaa cttgcttttt tctaccatat cagaatgatt
     4681 gtatttttta ttcagaaaaa taaaatactc cttctttttg gactgatttt atcgaaactt
     4741 attttttctt tttttcatgt attcttttat ttttataact agtgtattac ttcaaaattt
     4801 gatattatat ggcatgaaca gaattaaaat atcagttaaa ataaaagtta aggagcattg
     4861 tgtatgacaa ttaaaactag tctccaaaat caagcttacc aatctattcg ccgacaaatt
     4921 atctatgctg acttagaacc tggaaaaaaa gtatcagaaa aaaaattaga agaaacactt
     4981 tctattggtc gtacaccaat acgtgaagca ctgattcaac tccgacaaca aggtcttgtt
     5041 gatacaattc ctcaaagcgg aaattatatc tcattaattg atttagattc ggccaaaaat
     5101 gctcgatttg tcagagaaca tttggaacga caaattatgt tagagtgttg tgccaaaatg
     5161 aataaccaaa aaaaacggat tttagaaact ataatttcag aacaagaaaa agctgttagt
     5221 caaaaaaatg ctcgtagttt ttttcataat gataatttat tccataaagc ttgttttgaa
     5281 attgcagagc gagaagaagt atggcaatgg ttagaaaata acaatacaca cttagaacga
     5341 tttcgatggc tacgagtaaa aacggaagga ttaaagtggg aaaaaattat ggaacaacat
     5401 tatcaactat ttgaggcatt aacaaaacaa gatccagaag aagctaactt tctaacatcg
     5461 ttgcatcttc atttaatgct taatgagcaa aatattgttt tagctactca tccaaaatat
     5521 ttcaaaaata tataactttt aactcttttt aaattaaatg gttgttctga tcagaaaaat
     5581 atcgcttgtt ttcttattat gtaatatatt tcataaacta ttctgcataa caactattgt
     5641 ttgtactttt tacattggat aactaattat gactgctgat aacttttgat attaaactag
     5701 tatctccaat acaaataaaa aatagatatc ttgttcatca aaattagttc gtggatactt
     5761 accttcattt acatcattca gcggtttccc attttctttt attctattat ttcattttct
     5821 aatagacttg gcttcatttc gcaatacttt ttttcaatag gcatcaaatt ggtgttgttt
     5881 agatatttag ttgtagtttt gtgacatgat aagtatgctc ctttttctct tttccactaa
     5941 tacaacgatc aaagggtgct tttttcaaaa aactagaaaa atcaaaataa gattcgtatt
     6001 ttgattctat atatcctgtt tcaactacat cttatatttc acaatagaat aaatagcctt
     6061 ttgcatagct gcttaactta taagaaattg caatttactt cttcaaagtg aaaacgaata
     6121 tgagtaaaat aaaattattc ttcttacaga taattaaaaa tagcgcgtaa caaaaatcgg
     6181 cattcaatca cataattagg attgatgccg attacttata ttctacgtat agttttagta
     6241 ttcttatttt ttatcaccag taaccaattg agaacagccc taaagcagaa tagtctttta
     6301 tctcaaaacg cttaatttca ggcttaggaa tatgaataat cttttgagta tattctttct
     6361 cttttaatct tactgaagaa ataccactgc ctatcttttt tacaaatatt tcatttggtg
     6421 tacagactaa taaaacaata tttgtaatca atccttgcac taaagaatta aaaggaagac
     6481 tatttaaaac agggtgtgca taactataac atgtgaagta gttattttga actttaactt
//
LOCUS       DACBYO010000124         6401 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.124, whole genome shotgun sequence.
ACCESSION   DACBYO010000124 DACBYO010000000
VERSION     DACBYO010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.124"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(52..366)
                     /gene="trxA"
                     /locus_tag="IVD26_002683"
     CDS             complement(52..366)
                     /gene="trxA"
                     /locus_tag="IVD26_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAP6080591.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            complement(453..2813)
                     /locus_tag="IVD26_002684"
     CDS             complement(453..2813)
                     /locus_tag="IVD26_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAP6080592.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            complement(2928..3476)
                     /locus_tag="IVD26_002685"
     CDS             complement(2928..3476)
                     /locus_tag="IVD26_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAP6080593.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            complement(3535..3972)
                     /gene="zapA"
                     /locus_tag="IVD26_002686"
     CDS             complement(3535..3972)
                     /gene="zapA"
                     /locus_tag="IVD26_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAP6080594.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            4174..5091
                     /locus_tag="IVD26_002687"
     CDS             4174..5091
                     /locus_tag="IVD26_002687"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAP6080595.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            complement(5179..6090)
                     /locus_tag="IVD26_002688"
     CDS             complement(5179..6090)
                     /locus_tag="IVD26_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP6080596.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
BASE COUNT         1818 a         1371 c         1084 g         2128 t
ORIGIN      
        1 aggacggaac tggattcagt cccaccctca gcttattttt gctgtaagtt tttataaata
       61 ttgatcgatc atttgacgta gttgttcttt tgaatgaaca ccaacagctt tttctactac
      121 ttgaccatct tttttcaaca ttaatgttgg aatgctcatg ataccgaatt gttgaggagt
      181 ttctggattt tcatccacat ccattttagc aattctgaat tcttcttcat catattcttg
      241 ttccaactga tccaaaatcg gtgcttgcat acgacatgga ccacaccaag ttgcccaaaa
      301 atcaatcaat acaagtcctt tatctgtttc ttcattaaat gtcttatctg taattacttg
      361 tgacatatca aagacctcca tttttaaaat ctatgactag tatagcattt ctatacttgg
      421 atagcgaacc atctgcttac ctttagtaag ctttacttaa atttaacaat tgtcgcacca
      481 tttccgcctt ggtttgccgg tgcaaactca aagcttttga cgctccgatg gtttttaaga
      541 taatcagtaa ttcccttgcg aagtgcgcct gttccttttc cgtggacaat agtcacttga
      601 ggataaccag ctagaatggc agaatccaaa tattgatcta cctcacttag cgcttcttcg
      661 tatcgttttc ctcgaaggtc caattgattc ggcacgtgac tactagattc agatcgtaca
      721 gcatggataa ctcgttgtgt cggctctttt tgaggagcaa caggcgtcag ctcgtcttcg
      781 gacacattca tttttaatat accgatttct acttgccact gattcccgtt tttacgtaaa
      841 agcgtccctc tttggccgta agtcgtaacc aacacttcgt ctcccggttt caacgttttt
      901 tgttctttcg ccttcttcaa tactttattt ttcttcaaag tttcttcttg atgtagattt
      961 gctaattggg tctttgcatc gatcaactga tgctctttca catttccttg cccaatctgc
     1021 tgttgcattt tacgaatatc agcaatgatt ttttctgctt tttcttccgc ctctgacacg
     1081 acttcatttg cttttttctt tgctttttcc atttcttttt cacgttcttc aaagaaatag
     1141 ctgtaagctt ctttcaaatc atcgtgaagt tcttgtgcct cagaaacaaa atgacgcatt
     1201 tccagatatt cggtctctgc cattttccgg cgattctcta aatctgtgat catttcgttt
     1261 aaatcttggc tctcatcatt catcaactgc ttcgcttcat caataacttc tgtatcaaga
     1321 cctaatcggc tagagatttc aaacgcattg cttcgtccag gaacgccaat cagcaaacga
     1381 tacgttggac ttaatgtatc cacatcaaac tccatgctgg cattaatcgt atttgcccga
     1441 ttatatccat aaactttcaa ttcaggataa tgcgttgttg ccatcacata agcagacttt
     1501 ttaccaagat catctaagat tgcgattgct agagcagcac cttcttgcgg atctgttcct
     1561 gcaccgagct cgtcaaataa taccagactt ttttcattga cttttgataa aatatctaca
     1621 gtgttcgtca tatgagaaga aaaggtcgat agactttgct caatcgactg ttcgtctcct
     1681 atatccgcaa atacttcctc aaaaataccg atttgacttt cttcacctgc aggaatcggt
     1741 aatcctgctt gccccatcag ttgtaacaga cctaaagtct tcaacgtgat cgttttccca
     1801 cctgtgttag gtcctgtaat gacgatggct tgatagtctt ttccgattgt gatgtcatta
     1861 gaaactactt tttcctgatc gatcagtgga tgtcttgctt gtttcaagac gacatgattg
     1921 tcttcactga ttcccggcac gatagctttt acttctttac caaatcgtgc ttttgcattc
     1981 atcagatcca ttttaccaat cacataagca ttgtggatga tttcttgacg atggggaaca
     2041 agttcagcag aaagttcact taaaatacgt tgaatctcat ttcgttcagc gatttggtat
     2101 tgacgcaaac gattattcaa atccaccact tgttttggtt caataaataa agtctgtcct
     2161 gaagcacttt gatcgtggac tacaccgcca aatacaccgc ggtattcttg tttgactggg
     2221 ataacgtagc ggtcatttcg catggtgatg atcgcatcac ttaaatactt tgcatttttc
     2281 ccacggacga tcccatctaa ctgttcacga acagcttgtt cacttcgccg aatgttctgt
     2341 cttatgctct ttaactcagg agaagcgtca tcagtcacgc gtccgtcttc atcgattgct
     2401 tcctttaaac ggcggctcaa aacagggatc gtgactaact gatctgccca catatacaaa
     2461 cgtgcaaatt cgatttcact gtcataaaga tcatcaatga aacgattcaa ttcgcttgtc
     2521 gtagacaata ctctggaaac ttgtgcaagc tccactccat tcaagtctgc tccgatctca
     2581 atccgtttca tatggggacg gatattttca agtttaggta tagggatccc gcctcgcaga
     2641 cgttgcactt tcaatccatc ctcagtttct tgaagccagt ttgtgatcgt ttgttcctcg
     2701 ctcactggta ccaattctgc cagttcttct tttccttgtg cagtcactac aaattgtctg
     2761 accatctgtt tgactttttc aaattccaat gtttcaagga ttcggttatt cattttatca
     2821 ccttatcttt cactatgaaa aaagagctgt gccggacata cgctacgcag ccttcttaaa
     2881 taatctactc tgtacaaaaa acgaaatatt ttccagcact attttcctta attcaaaata
     2941 ttcgttaccc aaagctcata catcttgttg gtaagaaatg gcgttctctc aacgataaag
     3001 cgagcgaaac tatgctcgcc gaattgattt tggaccacat ctaatggaac aaaggcaagt
     3061 aactgcaaaa tcaaaaatat agtaacgtaa gccatgatta gtgacaggat gcctcctgca
     3121 atccagtcta cctgtctcaa gatcggcaca tacgtcaatc catggacaaa aacccccaca
     3181 aatcgggtaa gcagccagcc aattagcaaa ataatcagaa aagcagttcc tgcataaaaa
     3241 gcttcatcta ggtgaaaggc aaatacctga tcaaaaaatg ctaactttga tgttggcgtg
     3301 acagctgggt atggaatgta taattccaaa tgacttgcta atggtttgta aaaatgctgg
     3361 gcagcaataa atgacaatac atatccaatc gcgaatatga tttgcaaagc aaacccgcga
     3421 cgtgctccag aaaaaaacgc aattagcaat aaaaataaaa tcagcaaact cagcatgcta
     3481 cgttcctttc tcttctaact ttttttaaat ttttcttatt ttgataaaag gatcttaatt
     3541 agaagatttt tgtttaattt gtccttttcg tttctcgttt aaaatctgtt gtgcttccac
     3601 atgattttta atggtatgat ctgcttgacc attttctttc aatacttccc gagcttcgtt
     3661 ctcgattgct tcaatgcgtt tcacacgatt ttcaagctct gtaaatttga tcattttttt
     3721 ctttaattct gctgtttctt cttccagctc caagattctt tcttgtttct tcaattgatc
     3781 cgaaagcgca ttgacagcca tcaagattgc tgcttgttca ttatccattt gtggtgataa
     3841 ttgtttcaat tctgctaact gttcattgat cagcttcgtt acgatatcca tatgatgctt
     3901 ggtttcccgt ccgataatag tatatgtttg gttggcaatc accgctttgt agcgtgtttt
     3961 ttcgtgcgcc atacgaatca tttcctccta tttgatgaaa gttttattta gtgtaccatg
     4021 aagttggttc tttcaccgtt ctccacaaat atttttcaca tacttaacta ttatatgata
     4081 aactttaaaa aaatgctatg tctcgcaatc tcttagaaaa cgaaaagtcg tgagttgcgg
     4141 tatagtttta tgtataaaaa cgaggagaat tttatgagca acgtcattat caaagcaaca
     4201 aacgaccaac ttagtcaaat gaaagcatac tatcgctctt atttgttaaa taaacagatt
     4261 ccttatacta gctttgctgc aaaaaaagac gggacgacca ttaccgctta tacatccgga
     4321 aaagtgatgt ttcaaggtac gaatgcagca atagaagctg ataaatgggg ggaggcacag
     4381 gataaacaag ccaagccagc aaaaacagcc tcttctttgc caaaaaatat cagtcaatta
     4441 tccgttttag gtagtgatga ggtcggaaat ggcagctatt tcggtccgct aacagtatgt
     4501 gctgcttatg tgaaacgtga tcagcttgca gaattacgta aacttggtgt tagagattca
     4561 aaagagttaa aagatagcca aatcatccag cttgctgaca tcttaaaaaa aaccatcccc
     4621 tataaactgc ttgtcttatc tccagaaaaa tacaatgaga tccaaccaaa atacaatgcc
     4681 gttcggatga aagtcgcttt gcacaatcaa gcgatccatt tgctgctaaa aaaaatcgag
     4741 ccagaaaaac cagaagcgat tttgatcgat cagtttacgc cggaagcaaa ttttaaaaaa
     4801 tatgcgcgtt tagaaaaaaa tcaattacaa gaaaaactgt acttcgttac taaaggagaa
     4861 caatatcatt tagctgttgc tgctgcttct atcatcagtc gtgccagctt tttggaagag
     4921 ttacacaaag catcagctga agctggaatc acccttccat caggagctgg aacgaaatct
     4981 gaccaagtag cggcaaaact attggagaaa ggcggcatgc ctatgcttga aaaatatgcc
     5041 aaacttcact ttgcaaatac agaaaaagct ttgaagctac taaaaaaata aacggtgttc
     5101 aaaagcttgc atctgcgata ataagcccgg ccaaacgaaa aatatgagga gctatttttg
     5161 tttggctggg cttatttatt actgaaaata agtggtcaat gcttgtgtca aacttgcagc
     5221 aatctgctgc tgataactgt ctgttactaa ttcctttaaa tcactatcat tattcatata
     5281 acccatctcg attaaaatag aaggttgaag attttctcga agaacttgat agttcccagt
     5341 ggagattcct cttgaatcca gaggcagatc agtgaaggag tcagcaattg tctgtgctaa
     5401 tgtttcctct tgtccatagt aataatatgt cgtgattcca gttgcttcat tcgcatattc
     5461 cgtagagtct gcgtgtaaac tgataaagac atctgccttt ttttcttcac tgtagtcgca
     5521 tatatctcca agctgtacta attcatctgt agtatgggtc aaataaaccg ttgctccagc
     5581 atcctctagc gcctttttta cttttatggc tgtacttaat gttatatctt tttcttctgt
     5641 ttgttcatca ttgcttaatg ccccagtatc atttccgcca tgcccaggat ctaatacaat
     5701 cactgcatca gatagctctt ccggttttgt ttgtatattc tttgtgactt tggttccatc
     5761 ttcgagggct aaatatccag tatagccatc atttgtcttg atctgataag cattttttgt
     5821 ttcagaaaga aactccgcca gctctccgcc gtttatagtt gcaagtgggg tagttagcga
     5881 gtcatctgta tatagtgtac ggtcattttt tccgattttg attaatgtct cttgttctgt
     5941 atcatcaaat gattcctttg tctttgtaac cgtactgttc gtactgctga ccgtttgtcc
     6001 aactatcttt ttttgaccaa aaacatctat ttgaaaacag ataataatga taatgattgc
     6061 aaatacaaaa gctccaatta tttttttcat tcttgactct cacctcgtag atccagacta
     6121 agggccaaaa cttaaaatca gcttaagtaa gcaaaaaagg ggctgtaaaa gatataaccg
     6181 tagaaaataa cattactgct aaaatgattt ttttcatttt tggcatatcc tgaaatctcc
     6241 ttttgactat tcgtggtgat tcatctaccc aataaatagt ttccttcatt ctacaaacaa
     6301 ttaatttctt cgttattaaa ttaaaacact tcctggaaca ccgacataat aaataaaaat
     6361 ataccctgat aatcatgaga gaataacaaa tttgtcttta t
//
LOCUS       DACBYO010000125         6173 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.125, whole genome shotgun sequence.
ACCESSION   DACBYO010000125 DACBYO010000000
VERSION     DACBYO010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.125"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            725..811
                     /locus_tag="IVD26_002689"
     CDS             725..811
                     /locus_tag="IVD26_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAP6080597.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="IVD26_002690"
     CDS             complement(932..1621)
                     /locus_tag="IVD26_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080598.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="IVD26_002691"
     CDS             complement(1628..1906)
                     /locus_tag="IVD26_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080599.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="IVD26_002692"
     CDS             complement(1866..2780)
                     /locus_tag="IVD26_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP6080600.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="IVD26_002693"
     CDS             complement(2762..3142)
                     /locus_tag="IVD26_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP6080601.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="IVD26_002694"
     CDS             complement(3592..3879)
                     /locus_tag="IVD26_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP6080602.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="IVD26_002695"
     CDS             complement(3899..4123)
                     /locus_tag="IVD26_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HAP6080603.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4763..5296)
                     /locus_tag="IVD26_002696"
     CDS             complement(4763..5296)
                     /locus_tag="IVD26_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP6080604.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="IVD26_002697"
     CDS             complement(5317..6159)
                     /locus_tag="IVD26_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP6080605.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1152 c         1042 g         2346 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtcgatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DACBYO010000126         6031 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.126, whole genome shotgun sequence.
ACCESSION   DACBYO010000126 DACBYO010000000
VERSION     DACBYO010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.126"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            37..819
                     /locus_tag="IVD26_002698"
     CDS             37..819
                     /locus_tag="IVD26_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005469983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIB family hydrolase"
                     /protein_id="HAP6080606.1"
                     /translation="MSQKNARTMKHLPEDCFPFICSGREVEDINNILKKSGLRIPAVG
                     LNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKIYTNLGSYESQNYKNKMKKIFH
                     EVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDAISIYKFFIFIPNRQLKANIFN
                     HLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESIYNLKKPLRIAIGDSLNDLSMF
                     ESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFERILTI"
     gene            1100..2320
                     /locus_tag="IVD26_002699"
     CDS             1100..2320
                     /locus_tag="IVD26_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAP6080607.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2317..5037
                     /locus_tag="IVD26_002700"
     CDS             2317..5037
                     /locus_tag="IVD26_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6080608.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5021..5965
                     /locus_tag="IVD26_002701"
     CDS             5021..5965
                     /locus_tag="IVD26_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP6080609.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2249 a          954 c         1178 g         1650 t
ORIGIN      
        1 gatttagacg gtactctttt gaattctgac cagagcatta gtcaaaaaaa tgcaagaaca
       61 atgaaacatt taccggaaga ctgttttcca ttcatttgtt ctggaagaga agtagaagac
      121 attaataata ttctcaaaaa atctggttta aggataccag cagtagggtt aaatggttct
      181 gttggatttg atggagaaaa aaagatattt gagtcttcct tcgataaaaa tgatgtaaaa
      241 aaaattgatt ctgtcctatc gaaatttcca accaaaatat atacaaatct cggaagttat
      301 gaatctcaga attataaaaa taaaatgaaa aaaatttttc acgaggtagg gagtgaattt
      361 tctatcaaag agctaaacta tgagcttgag tatgaaaaat ctatttgttc aatcccttat
      421 aataatattg aggaaattat agaaaaggat gctatcagca tttacaaatt ttttattttt
      481 attcctaatc gtcaattgaa agctaatata tttaaccatt tgaaaaagat gctaaatgtg
      541 tctgttactg aatcggcacc tgtaaatatt gaaatcgtac ctcaaaatgt atctaaaggt
      601 gtggtgtttg atcgtttgga atcaatctac aatttaaaga aacctttgag aatcgcgatc
      661 ggagatagtt taaatgactt atctatgttt gaaagtgcag atattagttt tgcaatggga
      721 aatagtcatc aagaaatcat gaaaaaagct gattatgtca ctgtttcaaa tgataaagac
      781 ggagtatctc aagcatttga aagaattctt accatataaa ctaattaagg tagtatagaa
      841 catagaattc taaatacgga aaaatggagc ataaattcca gtacaaatag tacttcttca
      901 gtgtcaaacg aagcgaatat aacatagata tttaggattg tgacaaaaat catgtcacaa
      961 tctttttttc gaataaactt attttttgaa gtcggccatt tatcgtaatt tctttgcata
     1021 atacgaacaa attttcggtt attgatgaaa aaaaacattg aaaatggtat gataaaagaa
     1081 aaaaaggagg aaatttttaa tggtgaaatt tatccatgcg gcagatttac atatggatcg
     1141 gtcatttgaa ggactgacaa ctcttgataa aactgtacag gaaaaactat tgaagacgaa
     1201 tctgaccgtt ttatcaaata tcattgaaca ggcaataata aataacgttg attttgtttt
     1261 acttgcagga gataattttc atcaaaatcg tccttcatta aaaatacaga aacatttttc
     1321 agaacagatg aaacggttag aaaagaacca tatacctgta tttataatat tcggaaatca
     1381 tgatttctat caaaaagagc ggtattggtt ctcctttcct aaaaatgtcc atttatttac
     1441 atccgaaacg gtagagacaa aaaaaataac gataaaaagt ggagaaactg tctctctcag
     1501 tggatttagt tatcgtcaac cgtggattca aaaagacaaa gtgatggaat ttccttctag
     1561 agaactcaca gattaccata ttgggttgta ccacggggaa cctggcgtct ctcaaaaagg
     1621 aaactatgct cctttccaac cctcaaagat gcaagaaaag ggatacgatt attgggcttt
     1681 agggcatatc catgtgccaa cggtcttaaa tgaaaagcaa acaattgttt atccaggtgc
     1741 gcctcaaggt catactaaaa aggaacaagc ttctacatct attctactag ttgaattaag
     1801 taaaggaagt tgccaaatac atccgattaa agtagcagag gtctattgga agacaaagga
     1861 aatatcattg aggaaagcaa gaacgacaaa agaggtcatt gttcacattc gtcagcagct
     1921 ttcaaaagta gaggatggat ttagtttaat tgagataaaa ttaaaagatt atgaccatct
     1981 caatacagat gttttggaac ggatacaatc aggagagcta ttagactatt tgttagagga
     2041 attctcagat aggataaatg atttctttat ttggcgtatt tctctcatag agaatacttt
     2101 ttatacgaag accccacttg ctgcttctgc taaattgatg gaacagttat ttcaatacta
     2161 tcagacacct caagatttcc aacaaatttt aaatgaagta tatagtcatc aagaagcggc
     2221 tagaatattg agcgaactgc cggaatatca agaagaaaca cttgaaaaag ccaagcagct
     2281 gcttaatcaa gattttttat ttgaggagga tcaggaatga agattttaag gatcgagatt
     2341 gctgcttttg gaaaatggcg tcaaaaaagt tttgactttt attcaggcaa tcagctgatc
     2401 tatgggggaa acgaagcagg aaaatcaacg atttatcaat ttattcaagc aatattattt
     2461 ggtttccctt caaaaggccg taaaaaaaag gattatacac caaaagacgg ctcagcctat
     2521 ggcggcaaaa tatggcttaa acatcctgta tatggtgaat ttgctgtcga gcgctacaag
     2581 cagcaaaatc gcggaaaatc gaaggtgtgg ctgggggatc aagtgggaag tgatgagtta
     2641 ctagaaaaac tgatcgcacc tttgacgaaa gagttattcc agcaggtatt tactttccag
     2701 caagagcagt tgatggaact agatcatttg agagaaaaag agctacatga tgcgctgatt
     2761 tctttaggca tcacgggcag ttctcaagta ttccaaaagc ggcaagaata ttatcagaaa
     2821 gcacaacaat tattcaagaa aaaaggccaa aaattactaa tcaatcaaaa attaaatgaa
     2881 tggaaagagc tgcaagaaaa aattcatcaa aaacaagaac aggaagctta ttttggcaag
     2941 ttgatccaac aagaacagga atacgagtcg caacagcagc agttattggc acaattaaaa
     3001 gaggcgaaca aacaattttc attagccaga cagcaagaac ttaatttttc tttatatgaa
     3061 gaatggcaat ctctcaaaaa aaacagcact acaggtcttc ctgatgagca acttctttta
     3121 gatctggagt ctttctccaa acggtatcag caaacaaatg agcgtttgga agaattagaa
     3181 gcaacactgg aaaagcatag cgggatggat cagcagtcag ccagatatta tttttattta
     3241 gagcaggagc aggaactaaa agatctccag caacttcaat ttacagcgga acaattaaac
     3301 gaagaatggc aaagattaca aattgagact agagaaacaa attcagaatt gaagattttg
     3361 gaacaaaggt ggcattggca gaaaaatccg ttaccggaag aatttttata tgaagaagaa
     3421 tggaagcatc ttctggctga agaaagaagg attgctgatc tagaaagcca gatttctgtg
     3481 cgtctccaaa tagctaaaga acagcaagag atgattgaag cagaagtgaa tgacttggaa
     3541 gagacctatc cagcattatt acaaaatcag tcagagatag caccagtctc ttcatctaaa
     3601 ccgtatatgc tgatggctgg cggagcaata atcattgcag gtatatttgt accaatgccc
     3661 ttgaaagtga tccttttact aattggtgca ggcatgattg gctatttctt ctacaaaagg
     3721 caaccaaaaa ttaaaactaa aaatgatttc tctgagataa aaggaatgtg gcaagaaaaa
     3781 ctaggacaac ttgatctagc cttagctcaa ttagctgaag cagaagaaaa acaaaagaga
     3841 actggagaag aaaaacagat tcttcagcaa gaagtatatc gttttgcgga tcatcggcac
     3901 ttaggaaaga tggatacgct caaactcatg aaagaatatg gacaggaagt catagattat
     3961 cagaaattat atggcgtatt tgagcggaaa cataaaagag aacaggaaat acaagaaaaa
     4021 ctacgacaaa tcgaccaaaa atttgagttt gttaaagaat ggttaccgat acaagataag
     4081 acaatttcag aaaaaatggt attgctttcc cgttttatac aagagatgga acagatgaaa
     4141 tttgccagaa gctatcagca aaatacttta ttgaagcaag aaatcaatca attgaaaaag
     4201 aaacaaaaag tatggataca agaatacagc gaacaattga ctcaagcagg cttatcttat
     4261 ccttcggaag tacctgtctt tttacaaaaa gccaaacaag ccgaacagca gatgaaaaga
     4321 tacaatgaat tatcggaaat gcttactcca ctatttcctg aagagctgac aaaagagaaa
     4381 ttatctgtaa gactgcgcca actgaaagaa aagcaatccc aactccagca agaagaaaaa
     4441 gaagcaagtg aaaatcggca acgactccaa cttcaagtag aagagttgca aagagacggc
     4501 acattggacg aactttatca acaagctagc cggcaaaaag caaaattaca ggaattactg
     4561 gaggaatggg gagcacttga aatcgccggg acattcttag gtgatctttc aacagagatg
     4621 agtgaaagac aattacccca gttgttaaga gcagcaggtg attatttagg tattttaaca
     4681 aaaggaaatt atcagaagat attactgaaa aatgatacac tgactttaac agacggatat
     4741 acagaatttc ccatctatga gttatctaca ggtacgaaag atcagctgat tatggcgatg
     4801 agatttgctt acctctcatt agaagctaac cgttcgatat gcccgatcat cattgatgat
     4861 ggctggcttc attatgatca tcagcgaaag tatcaattag ctgaactttt agctaaattt
     4921 ggagaaaagt atcaaataat ttgtttttct tctgataaag aaatggtaag ctattaccat
     4981 gagatgaacc aaatcgtaaa acaattagaa ggagcaaata atgaaaaaaa ttcgtgattt
     5041 agtaatcgat gagcagtttg aacaatttgt cctgatcaaa agtgcagatg taagaatcgc
     5101 taaaaacgga aaaaaattta ttgcttttac tttccaagat acttcaggta ctatcgatgg
     5161 taaatactgg gatgcttcgg aggaggaaat caataaattt acagccggca cagtcgtttt
     5221 tctaaacggt aaaagagagg tttatcaagg aaaccctcaa gtaaagattc ttcatatgcg
     5281 cttaacaagg gtagatgagc caggagagcc tagtttatac atggaaagag cccctttgaa
     5341 gaaagaagaa atggaagaag aaatcaatca attgttgttt gagatcacca atgcgcattg
     5401 gaatcgtatt gttcgctatc tacttaataa atatcaaaaa caattttttg agtttccggc
     5461 agcaaaaaga aaccatcatg catttgccag tggattagct tatcatactt tgacaatgct
     5521 tcacttaggg aaatcaatcg ccgatgaata tcctgagctg aatcgagcat tgttgtatgc
     5581 tggtatcatt ttgcatgatt taggaaaggt gattgaactt tccggtccta tgtcgacaga
     5641 atatacgctt gcaggaaatt tgatcggtca tctggtattg attgacgaag aaataactaa
     5701 agcctgtctt gcgttgaaaa tcagcgaagc tgacgaagat gttctcgtat tacgtcatat
     5761 ggttttagca caccatggct tattagaata tggctcacct gtacgtccaa gaataatgga
     5821 agcagaaata ttacatcaaa tcgacaatat cgatgcttcg atgcagatga tgttgacttc
     5881 gattcgtcaa acagaaccag gaaaatacac cgatcggatt ttcggtatgg acaaccgaag
     5941 tttctatgta ccaaaagatt tatagcaaaa atttattttt ttcattcaaa acaaaaaaag
     6001 cgagacataa gtcttcgctt tttttgtttt c
//
LOCUS       DACBYO010000127         6014 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.127, whole genome shotgun sequence.
ACCESSION   DACBYO010000127 DACBYO010000000
VERSION     DACBYO010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.127"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(66..239)
                     /locus_tag="IVD26_002702"
     CDS             complement(66..239)
                     /locus_tag="IVD26_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP6080610.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            215..880
                     /locus_tag="IVD26_002703"
     CDS             215..880
                     /locus_tag="IVD26_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar diacid utilization regulator"
                     /protein_id="HAP6080611.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            complement(962..2128)
                     /gene="dnaJ"
                     /locus_tag="IVD26_002704"
     CDS             complement(962..2128)
                     /gene="dnaJ"
                     /locus_tag="IVD26_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAP6080612.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(2279..4108)
                     /gene="dnaK"
                     /locus_tag="IVD26_002705"
     CDS             complement(2279..4108)
                     /gene="dnaK"
                     /locus_tag="IVD26_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAP6080613.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(4159..4722)
                     /gene="grpE"
                     /locus_tag="IVD26_002706"
     CDS             complement(4159..4722)
                     /gene="grpE"
                     /locus_tag="IVD26_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAP6080614.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(4816..5859)
                     /gene="hrcA"
                     /locus_tag="IVD26_002707"
     CDS             complement(4816..5859)
                     /gene="hrcA"
                     /locus_tag="IVD26_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAP6080615.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
BASE COUNT         1579 a         1351 c         1056 g         2028 t
ORIGIN      
        1 aaaattagat ataaaattta ataaaaacca aaaatgcacg gtcgccatga agggaccgtg
       61 tatttttatc ttcttatttt ctcacctaat cgtatcagcc gcatcgcttg ttttcctgca
      121 caaacaagca atcgctctac ctgttccatc gcataagaaa gtaccatcgg ttcattgatg
      181 atatcaagta catagtcgat accaccctca cttaattgag cttgattttt cttctccata
      241 ttatgtagtt gtgggacaac tttctgacaa tcagcaattg tgtcaagaac ggatcaatcc
      301 tttattggag ttgctcgaaa gggtcttctc ttattacgga caggctttgc tcactgtaca
      361 tagacaacaa atcattatcc tagtcaatcg gatttccaga gcctcattgc tatcattgct
      421 tgataaaatc cagacaaagt ttaataaaat gtatcagtta cagctaaact ttggaattgg
      481 gtcgctttgt tatacagagc aagagacacc gcaatctttc cttcatgcca aacaagtttg
      541 cgaatggata gctttccatc aatctgtgaa cgagatccgc ttttttgaag atttagacct
      601 cgggatcgtt ttaccagcaa tcccgtcaga tcaacgaaca ttatatgtaa aacgtatttt
      661 gaaaagcctg acagaagaag aagtacattt gttcaagaag actttggcat gcttcagtaa
      721 aaataacgga agcatcaaaa attgctcaga agaattattt attcataaaa acaccttgca
      781 atatcgattg aacaagttcc attctctcac tggttatacc cctagaaact atgacgatta
      841 tcatattcta aagctggctt ttttgttggt acaaacatga caactacaaa aaaaccaggc
      901 gaacatatga ttgttcgtct ggtttttaat tattaatgac ttagcgtttt tactagaaaa
      961 actacttccg ctttttcccg ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt
     1021 gctgttcttc aactttgatg ccgccagctt cagcgaatgc acgtaatgct tctctttgtt
     1081 gttcatttag atttttcggt gtgatcagtt ttactttgac atgttggtcg cctgttgcac
     1141 caccacgtaa cttcggagcg ccttttccac gtaaacggaa gttcgtacct gtctgtgttc
     1201 cagcagggat cttcaatttc acatctccat ggacagttgg tacttggact tcatccccca
     1261 aagctgcttg tacaaaactt aaaggcaatt catagtaaat ttcagaacct tcacgatcaa
     1321 agatatcact ttcttctaca cggaagacca catacaaatc accaaatggt ccgccgtttt
     1381 ctccagcttc tccttgacca gctaaacgca tttgttgtcc ttcttctaca ccagctggta
     1441 cattcacttt aactgaatgt gctttcttct catgtcctga gccatgacag gttggacaag
     1501 gttctttgat ttctttccct gtcccatgac aaacatcaca agtttgacgg ctcatcactc
     1561 gtccaagtgg tgtttggcgt tctacattaa tcgtacctgc accatgacat ttatgacaag
     1621 tagttggttg tgtgcctggt tttgcaccgt tcccaccaca agtatgacag atttcttccc
     1681 gattatactt gatttctttt tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg
     1741 tatattgcaa atcagcacct tgacgaggcg catttggatc gactgaccga ccgcctcctc
     1801 caaagaaaga gtcgaagata tcttcaaaac caccgaagcc gccaccagag aagccgccga
     1861 atccaccaaa tccgccacca gctccaccag caccgtaatt tggatctgtg cctgcatgcc
     1921 cgtattggtc atatgcagcg cgtttttgcg ggtcacttaa aatctcatat gcttctgata
     1981 cttctttgaa tttttcttcc gcatcaggtt ctttattgat gtcaggatgg tattttttcg
     2041 aaagcttacg ataagctttc tttatttcat cttctgatgc tccttttgag agccctaaga
     2101 cttcataata atcacgtttt gttgccatag gctttcctcc tattggttct catcattttc
     2161 acgtcgcttg ttatcatatc atattttgtt tgaaacaaaa accgatactt caaactattt
     2221 ttcaaaagaa aaagccaaag tagcaacttt ggccttctct cgaaattcag tgaactgatt
     2281 atttatcgtc gccatcgact tcttcaaaat cagcatcaac gacatcatct gctccgcctt
     2341 gagctgcttc tgggttttct tgagcttgtt gttgtgccgc ttgttcgtat agtttaacag
     2401 tcaagttttg aacgatttcg ttcaatgcat cgcgtttagt tttcatttct tcgatgttgt
     2461 ttgcttcaac agcggctttc aattcatcgc gagctgtttc tgcttttttc acttcttctt
     2521 cgtccacttt gccttctaat tctttcaatg ttttgtccac agagaatagc aatgcatcta
     2581 catcattacg taggtcaact tcctctttac gagctttatc tgcttctgca tttgcttctg
     2641 catcttttac catacgttcg atttcttcgt ctgttagacc tgaagaagat ttgatcgtga
     2701 ttttttgttc tttttgtgta cctagatctt tcgcagatac atttacaatc ccgtttttat
     2761 caatatcgaa tgttacttcg atttgtggaa taccacgagg agctgctgga atatctgtca
     2821 attggaatct tcctagagtt ttgttgtcag cagccattgg gcgttcacct tgtaatacat
     2881 ggatgtctac tgctggttga ttatctgccg cagttgagaa tacttgtgat ttacttgttg
     2941 gaatcgttgt attgcggtca atcaatttag tgaacactcc acccattgtt tcgataccta
     3001 atgacaatgg tgtaacgtca agtaaaacaa catctttcac atcaccagtg atcacgccac
     3061 cttggatagc agcacccata gcaactactt catcagggtt aactgatttg tttggttctt
     3121 ttcctgtttc tttacgtact gcttctacaa ctgcagggat acgagtagat ccaccgacta
     3181 aaataacttc gtcgatttct gattgtgata aacctgcatc ttttagcgct tgacgtactg
     3241 gtacttttgt acgttctact aagtcagctg ttaattcatc aaattttgca cgtgtcaatg
     3301 tcatttccaa atgcaatggt ccagattctc ctgctgtgat aaatggcaag ctgatttgtg
     3361 tgcttgatac gccagataaa tcttttttcg ctttttcagc agcgtctttc aagcgttgta
     3421 aagccatttt gtcttgagac aagtcaatgc tgttttcttt tttgaattct gctaccatgt
     3481 agtcgatgat tttgttatca aagtcgtccc cacctagatg gttgtcgcca gctgttgaca
     3541 atacatcaaa gacaccgtct cctagttcaa ggatagatac gtcaaaagta ccgccaccaa
     3601 ggtcgaatac taagattttt tcgtcgcgat ctgttttatc taaaccatag gcaagagcag
     3661 ctgcagttgg ttcattgacg atacgttcta cttctagacc agcgatctta ccagcatctt
     3721 ttgttgcttg acgttgtgca tcattaaagt aagctggcac agtgataact gctttttcga
     3781 ctttttcacc taaatagtct tctgcgaatc ctttgatata ttgaaggatc attgctgaga
     3841 tttcttgtgg tgtatatgat ttaccttcta catctacttt gtaacctgct tcaccgatat
     3901 ggcgtttgat tgatgaaatc gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc
     3961 ctacttggat ttctccattt ttgaatgata caacagaagg tgttgtacgg tttccttctg
     4021 ggttagcgat gatttttgct tcgtttcctt ccaatactgc tactgcagag ttagtcgtac
     4081 ctaagtcaat accgataatt ttactcataa ttaacgtctc cttctttaat tgaaagtgta
     4141 agttttatat ccgcacaatt attgtgcaac aatgaccatg gttggtctta acacgcgatc
     4201 atgtaatttg tagccttctt gtagtacttc tacaatcgta tcggctggtg tatcttcagt
     4261 cgctggaaca gtttgtactg cttgatgaag attaggatca aaggcttctc ctttagcagg
     4321 gattttttca attccttctt cttccagtgc gttacgcaaa ctttccaaga ccatttccac
     4381 gccttttttc aaacctgccc cttgatcatc tgacacttct gtggctaatg cacgttccag
     4441 gttgtcaatt gatggaagta attttttggc taaatcttgt gaacggtatt tttgtaattg
     4501 ctcacgctca ttttttcctc gatttgccat atttgcgatt tcagcacgag cccgcaagta
     4561 tttatcttcc atttcttcta actcagcttt taatttcgct gtttcgaatt cttccgcttc
     4621 agcttctgaa atacccgaat cttctgcagc ttcgacatcg atttccggtt ctggctgagc
     4681 atctgtcatt tctttatcta gttcttcttg attttctttc acgatacagt cttcctttca
     4741 ttattcagtc agctgtttga ttgctcttac taagaaagag agaacgatca gctgcaaata
     4801 gcttcgttat tcacattacg agtttgacaa gtcaagcgaa cggtagtaat cagcaagttt
     4861 agctgctagt tctcttcgat aaacatcgac tagaccgaac atccgagaat aaggcatact
     4921 agtaggccct aacaaggcta ttgtacctct tccatgacca tctatctcgt aacttgcttg
     4981 aatcatactc atattctgca ataaatcatt gcctaattca gcaccaatct tgatatgaat
     5041 attgctatcc atcggagtga tcatttgtgt aagtccgtct gagtctttca taaaagaaaa
     5101 catcgatttg aactgatcaa gatcttgacg gggctcataa tccaagagat tcatttgtcc
     5161 actgacataa accttatctt caaaaacatg accaagaacg gtgtcaaata actgagacat
     5221 cccttctgtc gtttggaaat atttatgaag aatcatcgga atctccgtac gaagtttatg
     5281 gtacaccgtc atcagaggat ctccgactag acggtcgttt acaatctgta ccattttttc
     5341 tagttcctga cttcccatat attcgggaag agtgaacact tggctttcta cattccccat
     5401 atctgttacg acgatagcaa taatctgtcg attattcaag ggtacgatac gaaagccagt
     5461 cagtcggcgg tcttttattt caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga
     5521 taatatctca gcagattgct taataatctc attgatttca tgaaattctc tgcctagaga
     5581 ctgacgaatc agcagcaaat catcttctgc tacgcgagca ggttttaaca aatgatccac
     5641 gtaataacga tagcctaaag cagatggaat ccgcccagaa gaagagtgag tcttcaacag
     5701 caatccttca tcttctaatg ctttcatatc attgcgaatc gttgctgagc tggccttgac
     5761 tccctcagac atcaatgttt tggaaccaac gggcacgcca ctactcgtat agtgttggat
     5821 gatcagacgt aaaatgtcgt tttgtcgctt tgttaacatc ttcctcacct ctcattagca
     5881 ctcatatatt ctaagtgcta atccacttat aaatatagca agaagccctt ctcctgtcaa
     5941 gagaaagact ccatttttta gcactctaaa cacaagagtg ctaattctaa ataattgatg
     6001 taaatccagt tata
//
LOCUS       DACBYO010000128         5929 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.128, whole genome shotgun sequence.
ACCESSION   DACBYO010000128 DACBYO010000000
VERSION     DACBYO010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5929
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.128"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            25..1107
                     /locus_tag="IVD26_002708"
     CDS             25..1107
                     /locus_tag="IVD26_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017414133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6080616.1"
                     /translation="MNDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTDT
                     RVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINAE
                     FKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKIIS
                     LEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVKN
                     DGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKEDG
                     ELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISIT
                     MDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1325..2467)
                     /locus_tag="IVD26_002709"
     CDS             complement(1325..2467)
                     /locus_tag="IVD26_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6080617.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2472..2657)
                     /locus_tag="IVD26_002710"
     CDS             complement(2472..2657)
                     /locus_tag="IVD26_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP6080618.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(3011..3256)
                     /locus_tag="IVD26_002711"
     CDS             complement(3011..3256)
                     /locus_tag="IVD26_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6080619.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3250..3651)
                     /locus_tag="IVD26_002712"
     CDS             complement(3250..3651)
                     /locus_tag="IVD26_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP6080620.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3838..5646)
                     /gene="uidA"
                     /locus_tag="IVD26_002713"
     CDS             complement(3838..5646)
                     /gene="uidA"
                     /locus_tag="IVD26_002713"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HAP6080621.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5669..>5929)
                     /locus_tag="IVD26_002714"
     CDS             complement(5669..>5929)
                     /locus_tag="IVD26_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011609746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAP6080622.1"
                     /translation="TVQRIVWPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKT
                     YINTYDGKQETLEILVDKLMGLSEFKGVSPIDAYCGLKDTFI"
BASE COUNT         1923 a         1122 c          841 g         2043 t
ORIGIN      
        1 cttaattata caaacggcga agatatcaat gatgatggct caagaaaaaa agtggagaaa
       61 gttggcggag acacccgacc agaggccgaa gctgctttac gaaaagtttt atcagatatt
      121 gacgaaacag gacaatactt tttaggtacg gatactcgag taaaacaata ccttgatttt
      181 tggatggagg aatacgttaa actaaatcta aaatacaata cctatgaaaa ctaccgattt
      241 accatcaaaa atcatataaa cggttattta ggaaagaaaa aacttacgga tctctcccct
      301 gctcttttac aaaatttcat caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg
      361 actattactc actctgtcct taagaatgcg ctgaatatgg cggtttatcc ttggggatta
      421 atcaagcaaa atcctatgct gtatgtaaaa ataccaaaat atgaagcacg accaacgact
      481 aaaaaagatc taaaaatcat ttctcttgag gactttgatc atatgctaga aattactcct
      541 gaaggacatc ctttctatat tcctttgaat attggatttt atacgggaat gcgcgttggc
      601 gaagtttgtg gtctgacgtg ggatgatgtc gatttttcaa atggaacaat tactgtagag
      661 aaacaaatgg taaagaatga cggcgcatgg gtatatggta cgccaaagac aagcagttcc
      721 aatcgaacga tttttattgg acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa
      781 caattagaaa atcgaatgaa gtatggaaag ctctacattg attcaaatgc agtatgtacg
      841 aaggaagacg gtgagctagt tacgccaagt gtagtgaaat ggaatactag gaggatatcg
      901 aatgcactct ccctctcttt taacttccat tctctcagac atactcatgc tacacttctt
      961 ctcgaaaatg gcgcaaaaat gaaagaaatc tctgaacgat tgggccacag cagaatttca
     1021 attacgatgg atacttactc gcatgtaaca gataagatga gaaatgaaac ggtcgatatc
     1081 atggaaaatc ttagaaagaa ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa
     1141 ccggtggcaa atccatgtaa acatggttta ttttttacac tgttttcaaa caaacccttg
     1201 ctatttcttc ggttcgtcct cgtccatttt cgataccgac agctagctta taacccaagg
     1261 tatatcaaca taaaaaaata aaaataggct atgacagcag cgtgacagca aaaaagatgg
     1321 aaagttaaat atcaaacctc gtaatttcat ttgcgagtgc ttgatttgtt tctggatata
     1381 agtgtccata tttgtccaaa gtagttttaa tagaggcatg acctagacgc ttagatattg
     1441 catagatatt tttattatgt tcaattaaaa aggcaacatg cgagtgtctt aatccatgca
     1501 tatgaattgg ttttactcct gcaatttcag ctagtttttt tattctgctt aaaatagttc
     1561 ttggagatgg cggtaatcca tcaaaagaaa aaaccaattc tatatttttc ccaattgatt
     1621 gttgagtttt tttccatgtt tttaaatctt caacggtttg tctgtctaac gaaattatcc
     1681 gaatacttga tgtatttttt gtttcagcaa attcataatc ttgtcttgta cggatgtaaa
     1741 ttgacttatt tacgctacat ctgccattta ttaagtcaaa gtctttccat tgtaacgcta
     1801 agagctcctc actccttaca cctgtaacaa aaataaaacg catcaaacgt ttataaaatt
     1861 cttcataaaa atccccgtga taaacactat tatatacttt cttaaattca tcaactgtcc
     1921 aaaattctac ttgaggacgc tgagttttta ttttacctat agtatctaca ggattttctt
     1981 caataatttc aagtacaatt gcccttttaa aaactactct caacttattg aatatctgtt
     2041 taatataatt tggtgataat ggttgctcaa tgcccttttt tacaacatgg attttcgata
     2101 aaaactgttg aaattcctgt atatgaattg gtcgaatctt tacaacctgc atttctccaa
     2161 aaaaatccaa tgcacgttgt aaaatatgat ctgttttcat atatgttttt tctacagttc
     2221 ccaacttata ccaaggaaaa aaatactctc gataaaaatc atgaaacgtt attccttgca
     2281 gataaattcc ttgtgaatca gaaaaacttt gttttaactc ttcgagtccc cttctagctt
     2341 ctccttgagt tttgaagcct cttctggtca cttgaattct ttttccaaag cgatcttgtc
     2401 ctaaagttgc agaaaaaaac caagtgcctc tttttctgtc tttataaaca ttcgcaattt
     2461 tcctcatttt actattcctc ccaagaaata tggagaactt cttctaaaat tgaaatagga
     2521 attcttttta tttttgaatt acgataaaaa aagtatcctt tctcaactaa aagttcttta
     2581 cattccttga agattttatt agcatagtac tgagaaaaac ctagattaat caaatctttt
     2641 cgagtagctg ttttcattat agcaccttcc ttactttttt tcatttattt ctatcagctg
     2701 cttttgtcaa aagcacatag gaatttcacc tctccccaag tttacggcga gccttacgga
     2761 agtatcatta tcccaacttt aaatcatcgc tttttattga ctataaaaat tattttagaa
     2821 tatttatcgc tccttcttta cagcaagaaa tcatggcgca actaaaatat gctccttaaa
     2881 gtgttaacgt actgatagaa tctatttaat tttcaatgaa caataggttt tctacctaaa
     2941 agaatctact aattccttaa ctattagaag attcttttaa acagaaaaag tggaaagggg
     3001 atttttttaa ttagttaatt ttaaatttta agatcgcttc tattaattta atttctagct
     3061 gacttatcat atattcatct acataggtaa cgaattgacc tacctcgtta aatccatttg
     3121 tcaaacataa cttagccata taagaatgat aatgtttgag tatcatcttg atcgaaattg
     3181 gatctccttc tagagcagat aagataatgg atagtggaac taataggtac tgccgctttt
     3241 tagatttatc taccataggt cataccccat tttcaattgt tcaactgcct tctttcgttg
     3301 ataccagata ccacttgtgc tcatattgag aattttaccg atttcagcat cattaaaacc
     3361 tgcaaaataa taaagtagga taatctttct tcttatctcc gataactgat caattgctgc
     3421 tgataacttt tgatctgaaa ttaatatttc cattccaaat aagaaataga catcttgttc
     3481 atcaaaatga gtttgggaat acctgccttc atttgaatct gccaatggtt cctcattatc
     3541 ctttatgtta gcgtttcgtt ttcgaataga cttagcttcg tttcgtaata cttttttaca
     3601 gtaggcatca aattggtgtt gtatagatat gtcattgtaa tgttgttgca tgataatatg
     3661 ctcctttttc cccctttcca ctaatacaac aatcagaaag cccctttttt tcgaaaaaac
     3721 tagaaaaaaa acataaaaat atttatcatt ctttaaacag aaaatctttc tataaaaaac
     3781 aaaaaaaaac gattaggcta ggctaatcgt tttttgaaca ttcttaaaaa atccaaatta
     3841 ttttttataa ctgaaattgg gtattgatga ccatcgtttc tgtagatagt aagcaatcat
     3901 tttaggtttt ctatctctag taaagattcc tttcttattt ccttgcactc ttaaaatccc
     3961 ttgacttgtt gcaaaatctg caaaattcca cacttgttca ccaacaaaat tttcacatgt
     4021 atctattact tcgtgatttg cttcgtaata agccacttga tactcttctg taaacattgt
     4081 tggtactgta tcatgaaatc cagctactgt atctgctcca tattctgtaa acattattgg
     4141 cgtatcagga catctttcca tccatccatc tagctctttt ttcaacagat attttgcatg
     4201 tgccagatcc cctcccgaaa cataccaacc ataataacga tttaaacata aaacatcgac
     4261 aatatctcct accttacaaa catctggcgt tgattttaga taagtaacga ttgttacagg
     4321 tcttttctgc ggatcaagtt ctttagttaa ttcaactaaa ggttcaaaat attctttagc
     4381 accttcggaa tccgaatctg gttcatttgc aatagaccac attacaacac ttgggtggtt
     4441 cttgtcgcgt tctatcaatt ccttgatcac cgttttatga gaattttctg ttcgtatctc
     4501 tttccacgta ttatgttttt ccacattatc atctaataaa gtggccatga aatttaaatg
     4561 taaccctact gcaggtactt catcaataac tacaatacct tctcgatctg ctaatcgcat
     4621 aatttcttct gagtaaggat aatgtgatgt tctaaaagaa ttagcaccta tccatttcat
     4681 taaattaaaa tctttaatat ttacagcctc attcaaacca cgtccattaa catacgaatc
     4741 ctcatgctta ccaaatcctt taaaataaaa aggtttatta ttaatcaaaa atttgccatt
     4801 ggtaacctga acactgcgaa taccaaattc ttctgtatag gtatcgatca ctttattatc
     4861 atcaattaaa ctaattttca tactatataa ataagcgtct agaggttccc aaaaaattgg
     4921 attcttaagc tgaatcattc ctttctttcc ttcagcttca gctacaagtt gagcctcttc
     4981 gtcatatatc gctattaaga tttttccggt ccattctgta tcgatattga attctacact
     5041 tgcatccaaa tcagttattc ttgtattaat agtaatatca cttatatagt ctttcggagt
     5101 tgtatataac ttaacaggtc tatgaatacc tgcataattg aagaaatcaa aattaactaa
     5161 gttttccttt tttatatccc cattttcctg tactgtttcc ttcataatcc ccacaggtaa
     5221 agtactatcg tcaataatat tgtttacagc aactgtaatt cgattattcc cgtcttttac
     5281 aaaccgatta atttcagact caaatggtgt aaacccacct ttgtgttgag taataaactt
     5341 tccattcaaa aaaacttttg cttcatgtgt tgcagatcca aaacgaagaa ctaatctttc
     5401 ttctaataat cttttaggaa gagtcacttc tttttcatac cacacccatc caacatgatt
     5461 tctaatgttc tctgtttcaa ataaatcatt ataagaagag ggaactgaaa tcggataact
     5521 ctctttttca tttattggtt ctaaagcaag ttcttcctgt aagtcatcat ttgtatctaa
     5581 tttaaatctc cagagaccgc ttaagtcaat tacttgcctc gtctctgtca taatgggata
     5641 caacatataa accactccta tctaaatatt aaataaatgt atcctttaaa ccacaataag
     5701 catctattgg acttactccc ttaaattcag aaagacccat tagtttgtcc accaatattt
     5761 ctaaagtttc ttgttttcca tcataagtat taatataagt ctttacttga ggtacatcag
     5821 ccaaatgaaa cggacactgt acagatacaa aaattgttgg aatttcatga atgtaaaacg
     5881 gtatatccgg agttccttta cttgctggcc agacaattcg ttgaactgt
//
LOCUS       DACBYO010000129         5914 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.129, whole genome shotgun sequence.
ACCESSION   DACBYO010000129 DACBYO010000000
VERSION     DACBYO010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.129"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            248..2014
                     /locus_tag="IVD26_002715"
     CDS             248..2014
                     /locus_tag="IVD26_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAP6080623.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            2116..3375
                     /locus_tag="IVD26_002716"
     CDS             2116..3375
                     /locus_tag="IVD26_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP6080624.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            3522..4823
                     /locus_tag="IVD26_002717"
     CDS             3522..4823
                     /locus_tag="IVD26_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6080625.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            4826..5677
                     /locus_tag="IVD26_002718"
     CDS             4826..5677
                     /locus_tag="IVD26_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP6080626.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            5690..>5914
                     /locus_tag="IVD26_002719"
     CDS             5690..>5914
                     /locus_tag="IVD26_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAP6080627.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQK"
BASE COUNT         1902 a         1031 c         1203 g         1778 t
ORIGIN      
        1 aaactgttaa aaaactttta ctttagaaaa ttggagaaat tgatcgctta agataaattc
       61 aggacactaa atagtacagg aagtagacta aaacttttaa aagttttaag tctatctatt
      121 tggcaagttt aaaaaataaa aattcggtat caaaaaactg ttaccgataa catttttgaa
      181 agcgttgtct tttgcttctc tatcacttat agtgatgacg tcatattaaa acacaaggag
      241 gaaatcaatg gatacagctg caatttatca tcgaccggaa agtgaatatg catttctata
      301 tacgaataca agatttcgta ttcggcttcg tactaggaaa aatgatatca aaaaagtata
      361 tgtgctatgt ggagatccat ataccataac aactgaaaaa tggtatcaaa aacaacgacc
      421 aatgaaaaaa tgtctaagta ccaatgttca tgattattgg gaaattgaag tgacgagcga
      481 aacaagtcgc ttacagtatg cgttccatgt tgttggggaa gataacacgg actgttttta
      541 cggtgatcaa ggaatttttc cttatcgaga aaatgtgatt actgaaccaa atttttattt
      601 tcgaatacct tattttcatc aaatcgatcg attcactatt ccagaatggg taaaagaaac
      661 agtatggtat caaatttttc ccgaaagatt tgcaaacggg gacaaagcaa atgaccccga
      721 acacacttta ccttggggaa gtaaagatcc agaccgagaa gactttttcg ggggagattt
      781 gcaaggtgtg atggatcatt tggattactt gacggacctt ggcatcaatg gcatctattt
      841 ttgtcccata tttaaagcca catccaatca taaatacgat acgattgatt attatgaggt
      901 ggatcccgct tttggcgata aaaaactttt aaaaaacttg attgatgaag cacataaaag
      961 agggatacgt atcatgttcg atgctgtatt caatcatatg ggtgtccatt caccacagtg
     1021 gcaagacgtt ctcaaaaacg gagaaaaatc gatctataaa gactggttcc acatccgttt
     1081 tttcccagta gattcttatc agatgactga cttaccagaa actgctgaaa atatcccata
     1141 tgatactttt gcttttactc cattcatgcc gaaactaaat acagcaaatc cagaagtgca
     1201 aaaatatttg ctggatatcg caacttattg gataaaagaa ttcgatattg atggatggcg
     1261 tcttgatgtt gctaatgaag tcgatcatca tttttggaaa aaattcagag aagcagttac
     1321 agaaatcaaa ccagacatct atatccttgg agagatttgg cattcctctc aagcttggct
     1381 gcaaggggat gaattccatg cagtgatgaa ttatgcattt acagattcga ttaaagatta
     1441 ttttgcaaaa aagaaaatca cagcttcaca aatggtcagt ggaatgaatc atcagcaaat
     1501 gctttacaga gatcaggtga acgaaggaac attcaactta ttagattctc atgatactgc
     1561 caggatcttg accctttgcc aaggtaacaa agaattgatg aagtctgtga tggcctttat
     1621 gtttcttcaa aaagggtctc cttgtatcta ttacgggaca gaaataggga tgactggtga
     1681 agatgacccg gattgccgca aatgtatgat atgggagaag gaggaacaag atctagagct
     1741 attcggtttt ataaaagaac ttgtttctct aaggaaacag ttgtctaaga ttatttctga
     1801 aggttctact cagtggctaa tagtaaatga tcgtgaagat aagctctatt tcacacggaa
     1861 actagaggga cagatcatct atgtttactt taatcagtca aaagaacctt gggtagtaga
     1921 acaggaaaat gaggtgattc ttagtcaaaa ttgtcagttg ttagaagacg ggaaagcaga
     1981 gatacgacaa tacggatttt tgatcatgtg ttgaaaactg ttaccggtaa caacaagaaa
     2041 gcgtttgcaa atgaagattt gtgcccatta taataagggt gtaacagcac gttgaataca
     2101 aaggaggaaa tgaagatgaa aaaaagaagt gtgaaacagt tgggtttagg gttaatctct
     2161 ttaggaatct taggcggatt agcggcttgt ggcaatggta actcttcagc agaaggggaa
     2221 gccgatgaag gaaaaacgtt aacagtttcc gttgattctg gatataaaga ttatataaac
     2281 gaaataaaaa acactttcga aaaagaaaac gatgtgaaaa tcaagctagt agaaaaggac
     2341 atgttcgatc agttggaatc attagcgtta gatgggcctg ctggaaaggg acctgacgtt
     2401 atgatggcag catatgaccg gatcggtgcg ttaggacagc aaggacatct ggcggaagta
     2461 aaactgggaa atgaagcagc ttacgatgaa acagacaaag cccaagtgac ttatgatgga
     2521 aaaatctacg gagaacctgc agtaatcgag acccttgttt tgtactataa caaagattta
     2581 gtcgatacag caccatcaac gtttaaagat ttggagaatc tatccaaaga cagtcgtttt
     2641 gcttttgagt cagaagcagg aaaaaataca ggatttttag ctaaatggac tgacttttat
     2701 tattcctatg gtttaattgc aggttacggt ggctatgtat ttggtgatga tggcacaaat
     2761 ccttcagata tcggtttgaa taatgcaggt gctgtagaag gaatctctta tgcaacagat
     2821 tggttcaaaa atgtttggcc aaagggaatg caagacataa aaagtgcagg agacttcgcc
     2881 agccagcaat tcatgtccaa taaaactgca gcaatcattg acggtccatg gcaagcgcaa
     2941 acatacaaag aaaacaatat caattatggt gtagccaaaa ttcctactct aaataatgga
     3001 cagccttatc aaccgtttgg cggaggaaaa ggatgggtag tcagcaatta tgctaaaaac
     3061 aaagacctct ctcaaaaatg gcttgattat gtaacgaatc aggaaaatca agaaaaattc
     3121 tttgaaatgg taaatgaaat ccctgcaaac caacaagcta gggaaacagc aaaggctaaa
     3181 aacgatgaat taacaacagc tgtgattgaa caatatgaaa cagctcaagc gatgccaaac
     3241 atcccagaaa tgggcgaagt ttggacaggt gcagaaaact tgatgttcga tgcagcatca
     3301 ggttcaaaaa caccaaaaga atccgcagat gaagcagtaa aaacaatcag tgaagccata
     3361 gaacaaaaat actgattaaa atgataaccg tccattttta taaaaaatgg aacaggtgct
     3421 tcagataaaa gtggcaagag cgagatggaa aattatcttg ctcttgttgc cattatctta
     3481 aaagcagttt gcggtttagc aagtttagag ggggcattca gatgcagcaa gataaaacaa
     3541 gcaatatcaa cgaaaaaaaa atcacgcttt gttcacttat tccagggatg gggcagtttg
     3601 taaatggcca agcttttaaa ggtatcgttt ttttcgccat attcgtccta ttcattggtc
     3661 agatgcttct gggcggattt catgcattgg taggattggt tactttggga agtataccaa
     3721 tggaagatca ttcattattt attttgattg aaggcacttt gcaattcatc attacaatca
     3781 ttttcttgat tttttacggt ttgaatcttt tagacgctta tcgagtagcg aagatgcgtc
     3841 aagagggcaa aaaaatcaat cggacgatga aggaagtcat acataatata ggtgatgaag
     3901 gttttcctta tctattgaca cttcccgctt atcttctcat gatttttacg atcattttcc
     3961 cagtcctagt tacattgttc actgcattta ctaattatga cttcaatcat attccaccag
     4021 ccagtttaat tgattgggta ggggctaaaa acttttttag tatcttcttt ttaagctcat
     4081 atcgtaatac tttttttgca gtcttttcgt ggaccgtgat ttggacttta tgtgcaacaa
     4141 ctttgcaaat cacccttggt attctcacag cggttgttgc tcaccagaaa tttattaaat
     4201 tcaaacgtat tttcggtatc attttcttat taccatgggc ggtcccagct tttattacta
     4261 tcatgagttt ttcgaatata ttcaacgata gcgtaggtgc catcaatact caagtgattc
     4321 ctttcataaa ccagcttcct tttgtagata tcagtgcaat ctcttggaaa acggacccga
     4381 actggacgaa agtagcaatt atcttagtgc agggctggtt aggatttccc tatatctatg
     4441 tgatggttac aggaatctta caatcgattt cagaagactt atatgaagca gcaaaaatcg
     4501 acggagcaaa tgcatggcag cgcttttcaa acatcacgct tcctgctgtc ttcctagtgg
     4561 cagcgccaac atttattaca cagtatacgg ggaatttcaa taatttctcc atgatctatc
     4621 tgtttaacaa tggcggtccc ggaagcgtag gcggaggagc tggttctact gatattctta
     4681 tttcctggat ctataaactt acgactggaa cttctccgca gtattctatg gcttcagcaa
     4741 tcacgttgat tatctccgtc atcgttatct gtgtgtcatt gctggtattt aaaaagacaa
     4801 atgcgttcaa tatgggggat taacaatgaa aaaatttcat tcgagtgctc gattccaaaa
     4861 acgactttct cactttttta cttacttttt tcttttaata ctgtcagtca ttatcatcta
     4921 tccgcttttg atcacagcaa gtactgcctt caagtcagga aatattgcag cttttagttt
     4981 agatctttca agtgactgga ctttaggaaa ctttactcgg ctattcagtg aaacacttta
     5041 cgggacttgg tataaaaata cattgatcat ttctgtccta acaatgatcg tacaagtgac
     5101 tgtagtaact ttggcgggct atacttatag tcgctatcgt tttatcggcc gcaaatcaag
     5161 tttgatgttc tttttagtga ttcagatggt accgactatg gcagcattga ctgcctttta
     5221 tgtcatggct ttcttattag aagcgctcga taagtactgg ttcttgacaa tgatctatat
     5281 aggcggtgga attccaatga atacttggct gatgaaagga tactttgaca ctgtaccaat
     5341 agatttagat gaatctgcta aacttgatgg ggcagggcat ttcaggattt ttttccagat
     5401 tgtattaccg cttgtcaaac cgatgctcgc cgttcaagca ttatgggctt ttatgggacc
     5461 ttttggggat ttcatgttag ctaagttcct gcttcgaaca cctgaaaatc agactgttgc
     5521 tgtcggctta caaacattta tttctgatgt gacaaaccaa agagtctctc tttttgctgc
     5581 tggggcaatt ttgattgcac taccgatttg tctattattc ttctttttac aaaagaactt
     5641 tgttaccggc ctgacatctg gcggaacaaa aggataggag cagagtatca tgcaaacatt
     5701 tccgttaaac tatttttccg cattacgtac gccaactcaa gtgtttgcgg gacgcaaact
     5761 attatcatgg cctaaatttt tcttgatatt tgtattttta gtttccttga tggtcatgcc
     5821 tgtgactctt ttttatgcca atcagatcca agcgattcca ttagaacaat ttctatccgt
     5881 tcattcgctg atcgatgaac aaggaaccca aaaa
//
LOCUS       DACBYO010000130         5864 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.130, whole genome shotgun sequence.
ACCESSION   DACBYO010000130 DACBYO010000000
VERSION     DACBYO010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5864
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.130"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            196..921
                     /locus_tag="IVD26_002720"
     CDS             196..921
                     /locus_tag="IVD26_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080628.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            911..1420
                     /locus_tag="IVD26_002721"
     CDS             911..1420
                     /locus_tag="IVD26_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080629.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1490..2938)
                     /locus_tag="IVD26_002722"
     CDS             complement(1490..2938)
                     /locus_tag="IVD26_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6080630.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2938..3654)
                     /locus_tag="IVD26_002723"
     CDS             complement(2938..3654)
                     /locus_tag="IVD26_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6080631.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3635..3985)
                     /locus_tag="IVD26_002724"
     CDS             complement(3635..3985)
                     /locus_tag="IVD26_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAP6080632.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4129..4902
                     /locus_tag="IVD26_002725"
     CDS             4129..4902
                     /locus_tag="IVD26_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP6080633.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5073..5439
                     /gene="ssrA"
                     /locus_tag="IVD26_002726"
     tmRNA           5073..5439
                     /gene="ssrA"
                     /locus_tag="IVD26_002726"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(5744..>5864)
                     /locus_tag="IVD26_002727"
     CDS             complement(5744..>5864)
                     /locus_tag="IVD26_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6080634.1"
                     /translation="QGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
BASE COUNT         1705 a         1142 c         1020 g         1997 t
ORIGIN      
        1 aaaattattg tcgctgctcc tcttttcgaa taaacagtgt tcaaaagctt gcatctacgg
       61 taatagaata gggcagcttc ttcacaacct cttgcttttt acaaaatatt ttctggtttt
      121 aattcgtgat ttcactaaag gaatttcata ctttattcat attcattttc tatacttttt
      181 atagaggtga aaagtatgaa aataatccgc tatgctactg ctcgattaat ttattacaaa
      241 aagcagacaa tactctattg tttattttca agcttttctg cttttttatt gatagcatgc
      301 ctgactcttt accattcgca atcggcttta gccaatcaag tccaagatcg gctttcattt
      361 attggcgctt ctgcatctac agagcttctt ccggctttag aattagctag ccgattttat
      421 ataaaaggca tattcagttt attttttcta tttgccttcc tttttatctt tttcttttac
      481 tattcagtca ggcaaaacaa gcaggaattg atcaattggc gcctgactgg tctttctaaa
      541 accaaattat tcctttttat tttctggcag ctgttctttc ctctctttct ttgttgtatc
      601 ttggttttat tgtggatcgt cagcttccag tcagtttatg aagcgcttct tcaaaggatc
      661 aattttcttg tcttaaagac tactgaactg ccagatatcc gtgatatctt gacttcggta
      721 agcggactta caattccgat ggatcaacag acttttttta ccatcgattt ccaaaatgat
      781 ctttttttca cagatatact taagggattt gcccaaactc ttattgggct cagtggatgc
      841 tgtctcattc ttagtctatt ccctttcact ttttttatcc atcatttgca aagtaggagg
      901 cctggacgta atgaaacctg aatatttgat tcatgctgaa cacttgaccg ttattttgtg
      961 tcctctcgaa aaacagcata aaatattgga gcacttgaaa aaagaggttc ttgttgcaaa
     1021 actggataat tttgcgatca tccaaaaaaa ttggccgatg tttccttatc tgaatcttaa
     1081 agaccatgtc ctgttggatg taccggaaaa agaaatcaaa caagatcgtt tggcctatca
     1141 agaaaaactt gatatctctc cttccttgct taattgtgcg gcagctgagt tgacgtcttt
     1201 tgaaaaagta aagctgcaat tacttcatgc cttgctttcc aagcgaaaca atattgttat
     1261 tgaagataca tttgatgaac ttagtgtatt ggagatccaa gagctactcc acttgctttc
     1321 ttatttagct catgaagaaa atcaaggtat cttactcttt actcatgatg ctactattgc
     1381 tcaaagtcct tatattgatc gtttagagcc cgcgggctaa atcaatcatt ttatagtaaa
     1441 aacaagcggt atagaagatc gattcatgat cttttatacc gcttgttttt tactcttttt
     1501 tgatttctac gtcaggcaaa cgaacagcga attttgttcc ttttcctagt tcgctttcta
     1561 cttctaattt tcctttatgc aagcgtacaa gttgctgcac gattggtaaa cctaatcctg
     1621 attcaccata ttttgtattt tttcttgaag gatctacttt ataataacga tcccagatac
     1681 ttttcatttg ttgttcagac attccaattc ccgtatcttc aatcgtgatg atcgtttcaa
     1741 gatagccttt ttctaaagta atcgtgattt ggccgttttc agtaaactgt atcgcgtttt
     1801 gaataatatt gaccatgatt tggacaaatc ggtcataatc agcgtaaaca tcaatatcat
     1861 caacggcttt caatgtcaat gtatctcctg ctgcttctgc tttagcttct aactgtgcaa
     1921 caatattttt caatgtttct gttccattga attttttaat gaccatactg atttgattcg
     1981 tacggatttt ttcataatcc aagttttcat tcaccaaacg gatcagacgc tctgtttcat
     2041 ttttcatcaa tttaatcgcg ttttctcgct gattttcagg gattgcattg tattctaacc
     2101 cttccagaag tccgttgatt gtcgtaagag gtgttctcat ctcgtgagaa gcatctgcca
     2161 taaattgtct tcgacgattt tcttgttctt caatttctgc ttgagattct ttcaatgaat
     2221 tcgtcatttt attgaaatca tctgctaact catcaaattc atctttgtca tgtacgggga
     2281 gctgtacatc aaaattacca ttcgtcactt ctttcgtcgc attccttaac cgattgatac
     2341 gcttaacttg gaatgctgca aaagcatagc tggcaataac tgcaacgata ctggaaaaaa
     2401 taaatccttt gaacaggttc agtgtaattg gacgaacgct gttatcgata tttcgcgcag
     2461 gttgactaac tacaagtgct ccatagaatt catgattcaa attaaatggc acaagtgcgt
     2521 aagaggtcgc ctgtgcttgt cctaaaatat ttttattcga tgtgaatttt tcttgacgtc
     2581 cattcctcag atttttccat tgatcagctg ttaaggtaaa attcagtaaa gctgtattag
     2641 tcggataaat gacacgttcg tttttatcga taaatataaa gttcacattt tgttctgtca
     2701 gtacttgctc tgtcagcagc aatgcatttt gaaacgcctg atcttgacta aactgcggga
     2761 gcgtatcggc ataggtttgc gttgtctttt caactgattc agcatatcca aacagttgct
     2821 ggtaattgtt ttcttcaatc gtttgttttg tcagttgtgt aaaagaaact ccaacgatca
     2881 ataagatcaa cgcgaccatt ccgcaaaaag ctaagagttg ctgatacaaa taacgcatta
     2941 ggcaacacca gaatcatcga atttgtagcc gactccccaa acagtttgga tgacttgtgg
     3001 tccgaccttt tcgatttttt gtcgtaattt cttgatatgg gcgtccactg tccgttcatc
     3061 accaaagtac tgataatccc agactaattc aagcaactgc tcccgagaga atacttgacg
     3121 tggttttttt gctaaagtaa acaatagatc gaactcttta ggcgtcagtc cttcaattgg
     3181 ccggttgtcc agatacgctt ctcgtgtttt cgtattcatc ttgaaatgac tagtctcgat
     3241 atcaaaatga tcatctgaaa ctgctgcttc ttctcttgct tctgccaact cactacggcg
     3301 atgcaaagct ttcattcgag caataagcgt cagaggactg aaaggttttg tgacataatc
     3361 atctgccccc atctctaagc cgatcacctg atcgctttca gaatctctag ctgtcagcat
     3421 gataatcggc acagtacttg aaactttgcg gatctctctt cctactagca taccgtccag
     3481 tgtgggcaaa ttcaggtcta gtgtaatcat atcccaatgt tgtgggtttt ctaaaaaggc
     3541 atcgagccct tcttttccat catacttgaa agttgcttcc caaccttcat ttaagaaaaa
     3601 catctgcatc atttcagaaa cagattgatt atcttcaatc attaaaatat tcattatcgt
     3661 tccctccagt ttccaggtca tatttctgta atttcttttc tgtcataata aaaataggca
     3721 taattggaaa tactagcaga agcatttcaa tcagaaaata attcgtatgc ccagatgtct
     3781 ttaaataata gccgatcaat gccatcagta agcccataag aaaaaaccag tttccgcttg
     3841 tcttttgagc cagccgccaa tgagcgtctg tttttgcggc aagaggcgaa tgatacccat
     3901 aaaaaggcag atttcctttt gagggcagaa tccgaaaaag actgccaatt attaagaata
     3961 agataccaat actgaaaaaa atcattcttt ccctcctaaa ttctcttctt atagtatact
     4021 ctaaattgtt gactgaacca atatgttcag gaattcttca cgaaaggttt gtcttttgtt
     4081 cattctttgt taagataaac ttattccaat aaaaaaggag ttttatttgt gtcaaattat
     4141 cgtgcaatca ctttctttga tcttgatgga acattactag atgcgaaatc aaaaatcaca
     4201 cccgaagtgg caaaagctat gaacgcatta aaagaaaaca atgttctccc cgtcatcgct
     4261 acaggacgta cagaagcaga aatccactct atcatggaag atgcgggcat tacttctgcg
     4321 gtcaccatga atggttcttt cattcgagta gacggcgaag aaatctattc tcaaacattt
     4381 tcttcagaag aatgtcaaaa aatgtatgat catgtacagt tgaacggtca tgaactttct
     4441 tactataacg atcagaaaat ctggtgtacc ggtcatagcc aaacaatgat caatgcttac
     4501 gacttcattc attcagatgt tccggaaatt gatcctttag gctttaaaga aaacacagta
     4561 aatatgttgc tgatcttatc tcaatcaggt gacgaatact atcacgaaca ttttcctgag
     4621 ctaacttttt atcggaatgg tccttactcg atcgatacag tgaagaaagg aatctcaaaa
     4681 ggggcaggtg tcaaacgtct gcaaaaagaa cttcagctgg aaaaagttcc tacttttgga
     4741 tttggcgatg gtccgaatga ttttgccttg ttggaagctt gcgacaacaa aatcgctatg
     4801 gacaacgcct atgacggatt aaaagaactt tctaccttta tcacaaagaa aaatacagaa
     4861 ggcggaattg tccacgcatt gaagtatttt gatctgattt aagatctttt tttgaagcta
     4921 cctcttttct taagaaaatc gcttattttt tcttaagaaa ggggcagtta ttatataaat
     4981 aatgggatat gattcgcttt tttattgaat ttatcccaat atatgctata ctaattttgt
     5041 atgaaaaata cacgtaaccc ttgttagcta acggggacgt tacggattcg acaggcacag
     5101 tcgagcttga attgcgtttc gtaggttacg tctacgtaaa aacgttacag ttaaatataa
     5161 ctgctaaaaa cgaaaacaac tcttacgctt tagctgccta aaaacagtta gcgtagatcc
     5221 tctcggcatc gcccatgtgc tcgagtaagg gtcctaactt tagtgggata cgtttcaact
     5281 ttccgtctgt aagttgaaaa agagaacatc agactagcga tacagaatgc ctgtcactcg
     5341 gcaagctgta aagtgaatcc ttaaatgagt tgactatgaa cgtagatttt taagtggcga
     5401 tgtgtttgga cgcgggttcg actcccgccg tctccatata tgtatggttg agacagataa
     5461 acatgtatga aaaacgttgt taaatcaacg tttttttatt ttggtcaagg agagaaaagt
     5521 agagaaatac aaaatttttt gcattgattt tgcattcaaa aaaacattca aacatttaga
     5581 aatccccaat acgtattcag gaaaatctat tttaaggttt acaaaaagaa cttttgttcg
     5641 tacactcttt ttgaggtgaa cttttatgct gatggaagga aaaacacaat tatggtttaa
     5701 gcatgttcct tcaaataagt ttttttaatt attatttgtc aaattaagcg agacaaaact
     5761 ttccatttac gtaactcaaa aaaacttcta atggtgtttg gtaatttagt gattttctag
     5821 ggatatggtt tcttttggac gcaacggatg agatgaatcc ttga
//
LOCUS       DACBYO010000131         5749 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.131, whole genome shotgun sequence.
ACCESSION   DACBYO010000131 DACBYO010000000
VERSION     DACBYO010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.131"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            262..1254
                     /locus_tag="IVD26_002728"
     CDS             262..1254
                     /locus_tag="IVD26_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6080635.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            1314..2735
                     /locus_tag="IVD26_002729"
     CDS             1314..2735
                     /locus_tag="IVD26_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAP6080636.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            2728..4227
                     /locus_tag="IVD26_002730"
     CDS             2728..4227
                     /locus_tag="IVD26_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAP6080637.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            4266..5660
                     /gene="uxaC"
                     /locus_tag="IVD26_002731"
     CDS             4266..5660
                     /gene="uxaC"
                     /locus_tag="IVD26_002731"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAP6080638.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         1882 a         1066 c         1168 g         1633 t
ORIGIN      
        1 tattttataa aatactgtac ttttcttcat tttcttcctc tcctcctttt aaaataaaag
       61 gctttcattt ttctgtaaaa ttgatactca tctaattaaa tgagcattcc ccgctttcaa
      121 gaatagcata attaaaaata aaaatccaag taatttttaa cgtgtgcaat cttttcatat
      181 caaagatcta ttgacttatc gtagttatcg taatatgatg aatgcgttaa caaaaagtga
      241 aaaagtaagg aaaatgatgg aatggtaacg atcaaagata tcgctaaagc agctggcgtt
      301 tctcatacga cagtttctcg tgctttgaat aacagcagtt taataaaaaa tgaaacaaaa
      361 caaaaaatac gacaactagc taaggaaatg aattattcgc caaactatag tgcaaaaggt
      421 ttagtgaatc aaaaaaaata tctaatcgga ctatttttct caagtttgca taaaggaact
      481 tcatcaaatt tcctagcaga ttccattgca ggcatccatt cagtattaga cacaaattac
      541 agtttatctg ttgaaagtat cgatgttgtt gatttaacag aaatcaacct gcaacgctac
      601 gatggactga tcgttatgag tcaaagtgat gatgatcagc ctttcatcga ctatctcaaa
      661 gaaaaagaat ttcctttcgt tgttgtcaat cgtcacatca atgatccagc ggttatcaac
      721 gtcactgccg atgatgcggc cggtgttatg caggcagtag attacggtat tggatgcgga
      781 catacgaaga tcgcttatat tggcggaaag aaaaattttc gttcgacaaa agaacgggaa
      841 aaaggggtat tgaaaagtct aaaaaaagcg agcatccctg tcaatctagc ctatttttta
      901 acaggagatt acagcttaga aagcggcctc caaaacatgg aatacctatt atcactttct
      961 gacctgccta ctctggtttt ttgcggcaac gacgacatag cgattggtgc attgagagct
     1021 gtacatttag ctggcctccg tgttccccag aacatttctc tgatcgggtt cgatgattct
     1081 ccagtcgtct cctatctcaa tccgccgctt accaccgtac gtaagccttt gaaagaaatg
     1141 tgtcaagaag gaacaaagct tttactagat ttgatcgaag gcaggacgat cgaacaatct
     1201 aaaattgagc tctccacctt gttgatcctt cgtgagtcga tcaattactt gtaaactaca
     1261 agtaatttta tataaaaatg ttaacgtgtg cataacacag aaaggaagtt tatatgaaaa
     1321 aactgacaaa agaattagtg aaaaaaaacg aagcacctgt aaaagttctt cagtttggtg
     1381 aaggcaattt tatgcgtgga tttattgatt ggcagattca gcagctgaat aaccaacaat
     1441 tgtttaaagg taatgttgca atcattcaac ctttagaaca aggtcttgga aatatgatga
     1501 accagcaaga taatttatat acggtcattt tacaaggact cagcaatggc gaaatcgttg
     1561 atacttccga gattatcacc gtagtagaac aaatgatcaa tccttatgat gaatgggatg
     1621 cttatctatc tctagcagaa aatgacgact tggcctatat cgtctccaat acaacagagg
     1681 caggaatcca attcgtggag actgataatt taacagatac tcccccacag agcttcccgg
     1741 gcaaactgac agccttttta taccgacgtt tcaaattaaa caaagctggc tttaccatca
     1801 ttccttgcga actgattgac agaaacggcg aacgtctaaa agaaatcatt ttacgctacg
     1861 cagaaaaatg ggatttagaa cctgcttttg ttgagtggtt agaaaaagaa aatgttttct
     1921 gttgtagttt agttgatcgc atcgtcccag gttatcctcg cgaagatgca ggtgttttca
     1981 atcaacggca taactatgaa gatcaattga tggtcaaagc agaaccattc atgctttggg
     2041 tgatcgaagg gcctaaagaa ttggagaatc aactaccatt caaacaggct ggcttgaatg
     2101 tcatcatcac agatgatatg actccttatc gtgaacgtaa ggtgcatttg cttaatggac
     2161 cgcatacagc gatggtccct cttgctttgt tggcggaatt ggaaactgta gaagaagtaa
     2221 tgaaagatcc tttattctcc gcatatgttg atcagttatt caatctagaa ttgattccta
     2281 tgctttcttt acctaaagat gaattagcca tttatgctga ccaaatcaaa gaacgtttct
     2341 tgaatccttt tgcccatcac aaattagaag cgatttcatt aaatagtgtt tcaaagttca
     2401 gcacccgtct gcttccagtg ttcaagaagt atatcgaaga acaaaatcag gtaccaccgt
     2461 taatcactgt ttcactagct gcgctacttc ttatgtatcg aggcgatcaa gtaaagccac
     2521 atgatgatga aaagacgata agcgaattta ctgatgcttg gtctgataat ggaacagcta
     2581 ttcctcgatt attgcaaaac gctgcgcttt ggggagaaga tttgtctcaa ataccgaatg
     2641 tgacagatac agttcaagaa atagctgcaa agatcgatca aaaaggtgtc cggtcagtat
     2701 tacaagaaat gaaaggaacg atggtccatg cttgaaaccc tgcaaccaac aatgaaatta
     2761 aatcgacgag acagtgtggt cgtcgcatta acccctattc caaaacaaac acaactgacg
     2821 attgatcagc aaacgatcac cactcttgaa gatatcccgc aaggtcataa gattgcattg
     2881 ggtgatttga aagctggaga caacgtgatc aaatatggct atccaatcgg tcatgtgacg
     2941 acagacgtaa ctgccggtca atggctgcac actcataatg taaaaaccaa tctttctggt
     3001 gaattggatt atcgatatga aaaagatgtc catccaagtc attacctttt tgagaaccga
     3061 acatttcaag gttacttgcg aaaaaatgga aaagtaggga ttcgtaatga tttgttttta
     3121 gtacctaccg ttgggtgtgt gaatggcatt gctgaactga tcgtcaaaca gttcaaggaa
     3181 aaacatccag atctgggaca gtttgaccat attacgattt taaagcatcc ttatggctgt
     3241 tcgcagcttg gaaaagatca tcaaaatact cgagaaattt tagcggacgc agtaaatcat
     3301 cccaatgccg gaggagtttt agtatttgga ttaggttgtg agaacaatac agttcctgaa
     3361 ttcaaaaaaa ttttaggtga atatgatgaa gaacgagtga aatttctagt ggctcaagat
     3421 gtttacgatg agatcgaaca aggtgtggct ctattagaag agcttttaac agcggcggaa
     3481 aatgaccagc gcatatcagt cccgctctct aagttgaatg tcggtttgaa atgcggcggt
     3541 tctgatggtc tatcgggaat aactgctaat cctttacttg gtgcattttc tgactacttg
     3601 attgctcaag gaggcagcac gatcttaaca gaagtgccag aaatgtttgg cgcagaacaa
     3661 gtattgatgg cacgagcgga aaatgaagaa gtttttgact caatcgttga cttgatcaat
     3721 gacttcaaac agtatttctt gtcttacggg gaaccagttt acgaaaaccc atctcctggt
     3781 aataaagcag gtgggatcac tacattagaa gataagtctt taggctgcac gcaaaaatca
     3841 ggaagctctc ctgtcgttga tgtgctacaa tatggcgaaa aaatcagaaa accagggctt
     3901 agtttattgc aagctcccgg gaatgatctt gtagctgcct ctgctcttgc ttcatccgat
     3961 tgccagttgg tcttgtttac cacaggaaga gggactccgt ttggctcata tgtcccaacg
     4021 gtcaaggtat ctacgaatac aactcttttt gaacgcaaag gtcattggat ggattttaat
     4081 gcaggcgtct tattagaaca accaatggaa gtaatcttag aatcgtttgt tcaaaaaatc
     4141 atcgctgtag ctagtggaga agaaacgaaa aatgaacaaa atgacgttcg agaaattgcc
     4201 atttttaaaa acggagtaac actttgattt tcataaaaca gtataaaaag aaagaaggaa
     4261 gatttatgtt tttatctgat gattttttat taaaagacga ttgggcgaaa aagctttacc
     4321 attcctacgc aaaaaacatg cccattattg attatcactg tcacttagat ccaaaagaaa
     4381 tttacgaaaa caacaatttc agcaatctga cagaagcttg gttaggaggc gatcattaca
     4441 aatggcgctt gatgcgagct tgcggcgtgc ctgaagaaaa aatcacagga aatgcttctg
     4501 attttgaaaa atttttagct tggtgtcaaa ccgtaccaaa aattatcgga aatccgcttt
     4561 acagttggtc acatcttgaa ttgaagcgtt tcttcggtat tgacttgttg ataaatgaag
     4621 aaaatgcaga gaaaatttgg acacaagcaa atgaaatttt ggcagctcct gattttcgcc
     4681 gtcgggaaat cgcaaaaaaa tcgaatgtag aagtgatttg tacaacagat gatcccgcag
     4741 acgacttgca ctatcatcag ttgcttgctc atgaagaacc agatttgaag gttctacctt
     4801 cattccgtcc agataaagca ctcaatattg aaaaagaagg atttaatgca tgggtcacac
     4861 tactggaaga agcagctgac caaacgatca ccacctatca agaactgata gaagtcttag
     4921 ggcagcggat agaatacttc catcaacatg gatgtcgtgt ttccgaccac gctttagaca
     4981 tcttacgcta taaagaagcg gatgaaacag tattagaaga gatttttcaa aaagcacgag
     5041 ctaacaaact attatcttca gatgaaatcg atgcttatct tacagaaaca ctgatacatt
     5101 tgacccactt ctatcattct cataattgga cgatgcagct gcacatccat gcttatcgta
     5161 actgtaatac acaaatgttg gaaaaattag ggcccgatac cggctatgat ggaatgaatg
     5221 atctttcttt gactattcct ctgcaaaaat tattgaaccg tgcagaagaa acggatcagt
     5281 tgccaaagac gatcctttat tcattgaatc cgaatgacta tcctgcgatt ttagctttga
     5341 tgggctgttt ccaaaaagaa cagaatggaa aactgcagtt aggttctgga tggtggtaca
     5401 acgatactcg agctggtatg cgcgatcaat tgacacaatt tgctgatggt agtgctttgg
     5461 ggaattttgt cggcatgctg acagattcaa gaagtttcct gtcctacact agacatgaat
     5521 atttccgtcg tgttctttgt gaatttttag gcgaaatggt catgcgagga gaagcacctg
     5581 aagatgaaca acttttagga agtctagttc aagcgattag ttatacaaat gctaaaaatt
     5641 actttggctt ttttgcctaa ttgattaata gtaacagtaa cgaatcaaaa acaggatagt
     5701 gaaataacgg aatccgttta tccacgtttt agagaagaag acggaccaa
//
LOCUS       DACBYO010000132         5689 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.132, whole genome shotgun sequence.
ACCESSION   DACBYO010000132 DACBYO010000000
VERSION     DACBYO010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.132"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(488..1297)
                     /locus_tag="IVD26_002732"
     CDS             complement(488..1297)
                     /locus_tag="IVD26_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP6080639.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="IVD26_002733"
     CDS             complement(1297..2043)
                     /locus_tag="IVD26_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP6080640.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="IVD26_002734"
     CDS             complement(2061..2528)
                     /locus_tag="IVD26_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6080641.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="IVD26_002735"
     CDS             complement(2528..2938)
                     /locus_tag="IVD26_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP6080642.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="IVD26_002736"
     CDS             complement(2949..3962)
                     /locus_tag="IVD26_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009141002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6080643.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="IVD26_002737"
     CDS             4179..4913
                     /locus_tag="IVD26_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6080644.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..5607
                     /locus_tag="IVD26_002738"
     CDS             4897..5607
                     /locus_tag="IVD26_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6080645.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1832 a         1195 c          943 g         1719 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgctgt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatccggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa
     5641 agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DACBYO010000133         5636 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.133, whole genome shotgun sequence.
ACCESSION   DACBYO010000133 DACBYO010000000
VERSION     DACBYO010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.133"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(114..1889)
                     /locus_tag="IVD26_002739"
     CDS             complement(114..1889)
                     /locus_tag="IVD26_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAP6080646.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(2102..3004)
                     /locus_tag="IVD26_002740"
     CDS             complement(2102..3004)
                     /locus_tag="IVD26_002740"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAP6080647.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            3283..5628
                     /locus_tag="IVD26_002741"
     CDS             3283..5628
                     /locus_tag="IVD26_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAP6080648.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
BASE COUNT         1794 a         1115 c         1072 g         1655 t
ORIGIN      
        1 tagtcctcaa ggctttgttc gaactttctt tcactcttca ctataatcta aaaatagaaa
       61 atagaggaga acatcattcg tcaatgatgt tctcctctaa tcttagtatg tttttatttg
      121 gaagataaag cttttttcag attcaattta ctgaaaacta gcatgcttgt tactacgatg
      181 aattgcgtta atggcacgcc tgcgccagtg tagacactta aaaaataatc ctttttttct
      241 ggcgcataag aacaaaacca cgagacgccg aaaagaaaaa ccaattgtgt cagtattaat
      301 ccggtgacta caatcaaaga ggaactataa taggcacgat cagcttttgc aaatgcggtt
      361 cctagtatca taagtaatat ccctgctatt gaagcaatca gcacgggaat ggccagaact
      421 tggtaaattt ttatcatgac attcgcgact tttgctgttt ttgtcaactg gaaatcaggt
      481 gttctcggat cactgctatc gatccaatta tccattagtg gaagattcaa taattcttgg
      541 gcctgttcga cttgttcttg cgtaccgaaa ctataattcc ccccttgatg gaaatctttg
      601 tatcgccatg cataggcata tcctgatttc agaaaagcaa atacgattgg cagatcattc
      661 atcgtctttc catcccctga tcccatcaga tagaattctt ttttcttttt gatagttccc
      721 ttttgatagg cttcttctaa ttcttgattg acttttttcc aaaaatcatt ggtttctttt
      781 gcattgtttt ggtaataacc agattcgctt accacatctc gcaatgccca aaaaatgata
      841 tctcctggta attcttttac ttttccacct tgggtccacg catgagtcgt atacaattcg
      901 tcaatacgag tagaaacagc atgaaatgta ggagatgcgt ctaatgcttt atttaatgca
      961 gcatgcgaga cccatatctc actgttttct ttatttaagt tcgtttcgtc atctattcgg
     1021 atcagctgtt tcatcaaacg tccaaattcg ccactcgaac ggtcattgat ggcggcaata
     1081 ctatatgttg tctcgttttt atattcgatc cactgataga cgatggagaa accgactaga
     1141 gggagtaaaa acaatgaaag tttcagccat tcttgtttcg aaaggagaaa tggtcgttct
     1201 tttaacttct ttgcttcttt gaaagaaaag tcttgtccta gcaagatctg gacgaaactg
     1261 atgcctaacg cgactacagt aaaaggaaga agccagatgg aatcttcgcg aatgaaccaa
     1321 aagaaaggaa aagaaacagc tagccctaaa aaccacggca gcattttttt gctggaacta
     1381 tatttacggt aataaatagc tagtaaacaa gcgataatga tctcaacagc cggaatcacg
     1441 agggcattac gatacgttcg agtggaatat tcatgtgtaa aactaatcgg agaaaacaaa
     1501 aaataaaaat agaaacttaa aagaagatac ttgttcttca cgatcggttt aaacgcgagt
     1561 gcaaccaata tactggcaaa aatactgaac atgccgaaca aaactgcata agaaagatgc
     1621 agtttatgtg caagtactaa aaataagctg taggagattc ctttggaaag tgttgtagtc
     1681 gtatactccc ctagccattt accgtccaaa atattttgag catagcgaat cagcagctgg
     1741 tcatcatagg ttgccgacat gtctgttcca tagattgctt tactatataa atacaaacga
     1801 ataattgtaa ataatagggc tatgccaaga ataaagtatg tatgtttctt ttttagttgg
     1861 ttgatcaagg gttttaaagt gttcagcatc ttttcgtcct tccaatcacg ttttgccact
     1921 tgcttgtgaa acttttcgtt tttttacttt tctaccagta taccctgttt gtctaaattt
     1981 aaaaagaggg gggagaagat gcatgatgaa aaagactgca aaaagcactc ctttgtttct
     2041 taaacaaaaa aggacaaggc aatgtgcctg gtcctttttt gctgctgtca gatagaaaat
     2101 cttagagtat cacttcttct gctaataact caggaaacac ttctggatcg aatatttgtg
     2161 ctttgaacat ggcgatttct tttccatatg gtgcgtaagc tttcttttta tctttgccga
     2221 catagggagt ttccaagatt ttcgaaatat tgtcaaacat tggatcatgg acgatcttat
     2281 tcagcgtgtc gaatccgatt gttccaaaac caatattggc gtgccggtct ttatgcgaac
     2341 cttgcggatt tttagaatca ttgatatgga gtactttaag ccgatctaac ccgatgatct
     2401 tatcaaactc ttccattaca cctgaaaagt cttctttaat attataaccg gcatcattcg
     2461 tatgacaggt gtcaaaagta acggataatt tttcattcaa ttttactcca tcgatgattt
     2521 gcgctaattc ctcaaatgtt cgaccgattt ccgtaccttt acctgccatt gtctccaaag
     2581 cgatttgtgc cgtctgttct tttgtcaaaa cttcattcaa gccttcaata attctagcaa
     2641 ttccggcttc tgttcctgcc cctacatgag cacctgggtg aagtgtaatt tgagtagcgc
     2701 ctaaagcttc cgcacgaaca atctcttctc tcagaaattg gacggcaaaa ggaaacattt
     2761 ctggtttgat cgtattcccc aaattaatga tataaggggc atgaacgacg atatttgtta
     2821 gaccgttttc tgccatgtac gcttttccgg catcaatatt catctcttcg atggcttttc
     2881 ttctagtgtt ttgaggggcg cctgtataga tcataaaagt cgaagatcca taactggctg
     2941 cttcttctgc tgctcctaac agcattttct ttccgctcat gctgacgtgt gagcctaata
     3001 acatggatgg attcctcctt gaaaggcaat tgttactaac aattcctata tattggtaag
     3061 atgatataca aagaaaatga ttgatttttc tttgccctgt tctccatagt aactgaaatt
     3121 ttctctaaag aaaagcttaa gaactctttt ataaaaaaga tcattttctc acgttttaac
     3181 tcttttaaaa aagaaattcc tgccaaaaac agccttgtct gtttttttgt tctattattt
     3241 gctataatta gcgaaataaa accattagtt gaggtgaccc ttttgccacg caaaaatact
     3301 cgaaaaaaac agaatagaag aaaaaaagaa aaatggtttg ttcctaagat tatttttaga
     3361 gtttttcaat cattgactgt ttttattact gttcttcttt tgatgttcgc agctctaggt
     3421 attggaatag gcgctggcta ttttgcctat ctcgtcgaag acacacaatt gccgactaaa
     3481 aaagcactgc agacagaact aggaaacatt acagaaacgt caaagattgt ttatgcagat
     3541 aatacagaga tatcaaaaat ccagacagat ctgatgcgca cgactatttc atctgataaa
     3601 atttcacctt tattgaaaac tgcaattatc agcacagagg atgaatactt cgataaacac
     3661 caaggttacg ttcctaaagc tgttttacga gcattagtat ctgaagctac tggtattggc
     3721 tcttctggtg gatcaacttt gacacagcaa ttagtcaaac agcagatcct tacagatgaa
     3781 acaacattca aacgtaaagc aaacgagatc attctttctg cacaagtaga aaaatacttt
     3841 tcaaaagatg agatcattgc tacgtatttg aatgtctcac catttggtcg taataataag
     3901 ggacaaaaca ttgctggagt ccaggaagct gcaagaggaa tctttggtgt agatgcaaaa
     3961 gatgtgacgc tgccgcaagc tgcttatatc gctggattac cccaaagccc gatcacgtat
     4021 agtccataca cgaacacagg tgcgctaaaa gaagatcttt ctgccggcct tgccagaaaa
     4081 gattttgttt tattcagtat gtatcgtgaa ggccaaatta cgaaagaaca atacgaagaa
     4141 gcaaaagcct atgaccttac aaaagacttt ctaccacaac aaatcgcaga acagactgac
     4201 agagaattct tgtattatac tgtgatgaat gaagcaacaa gaatcattgc acaacaattg
     4261 gctgaaaaag acaacgctga tatgtctgat tcatcggtca gtgacgctta ttatcaaaag
     4321 gcacagcaaa cgatccaaaa taaaggatat acaatccatt cgacaatcga taaagatgtc
     4381 tatgctgcat tgcaaaatgg cgtagaaaat tatggataca tgttagatga tggtgctggc
     4441 agtcaagtag aaaccggaaa tgtattgatg gataacagaa ctggccgcat ctacggattc
     4501 gttggcggac ggaattacag tcagaatcaa aataaccatg ccttcgatac agaacgtcaa
     4561 gctggctcat caatcaaacc agttcttgtt tatggacctg caatcgacat ggggcttatc
     4621 ggatcagaat cccgtgtatc agattatgca acaacttggc aagaaggaga aaatgctggc
     4681 gagaaaatcg tcaatgctac taacgaagga tcgaacacct tccaaaccgt ccgtgagtca
     4741 ctagaatggt ccaacaatat cccggcttat cacttatatc aagatgtgtt gaattccggt
     4801 ggatcgaaac aatatgctta cgagcactac ttggcaaaga tgaactaccc ggcaaatgac
     4861 aattggggcg ttgaatctgc tcctttaggt acagtagatg tcacgacgct tcaacagacc
     4921 aatggatttc aggctttagc aaacggcggc gtctatgaag aaggctatat catcgattcc
     4981 atcacagata acgcaggaaa tgtaatttat aaacacgaaa gcaactctgt ccggatctat
     5041 tcggaagcaa cggcatcgat catgaatgac atgatgcgca gtgtgatcaa tgcaaaaatc
     5101 actacaccat tcaaagatgc catctcaagc ttaaacggaa atctaggaaa agcagattgg
     5161 gtcggaaaaa ctggttctac caatgaatac cgagattcat ggctaattgt ctctactccg
     5221 tctattacca tcagtagctg ggcagggcac gatgacaata ctggaatgga cagcaaagca
     5281 aggatacgtt cggctaatta tcttgccaat ctgatcaatc aagcttacca agcaaaacct
     5341 gacatttttg gcactgatga gaaattcgaa ttatcatctg atgtgatgaa gaaaaaagta
     5401 tctggattta ctggtcaaac acctggaaaa gttactgtca ataaaaaatc catccaaaca
     5461 ccaggaaaaa cagttgaatc gctatgggcg aaaaatggac cgaagaaaag cgcctttaaa
     5521 tttggcgttg gcggtaccga tgaaaactat acagattact ggaacaccgc ttcagcttat
     5581 gcaagagcga atcaagcaac caaagaatca gatgagaaag atgattgatt taatag
//
LOCUS       DACBYO010000134         5444 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.134, whole genome shotgun sequence.
ACCESSION   DACBYO010000134 DACBYO010000000
VERSION     DACBYO010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.134"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..571)
                     /locus_tag="IVD26_002742"
     CDS             complement(<1..571)
                     /locus_tag="IVD26_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAP6080649.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
     gene            complement(905..992)
                     /locus_tag="IVD26_002743"
     tRNA            complement(905..992)
                     /locus_tag="IVD26_002743"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(958..960),aa:Ser,seq:cga)
     gene            complement(1137..1703)
                     /locus_tag="IVD26_002744"
     CDS             complement(1137..1703)
                     /locus_tag="IVD26_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6080650.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            1958..3289
                     /locus_tag="IVD26_002745"
     CDS             1958..3289
                     /locus_tag="IVD26_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAP6080651.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            3255..3605
                     /locus_tag="IVD26_002746"
     CDS             3255..3605
                     /locus_tag="IVD26_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080652.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(3697..4116)
                     /locus_tag="IVD26_002747"
     CDS             complement(3697..4116)
                     /locus_tag="IVD26_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAP6080653.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(4117..4461)
                     /locus_tag="IVD26_002748"
     CDS             complement(4117..4461)
                     /locus_tag="IVD26_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAP6080654.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            4811..5407
                     /locus_tag="IVD26_002749"
     CDS             4811..5407
                     /locus_tag="IVD26_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP6080655.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1513 a         1008 c          930 g         1993 t
ORIGIN      
        1 ttccatttga tagcgagcga taattgttca gattaaataa ttgataatca aatggcggat
       61 tatttgtcaa cacaccgaca ggattatcat ataaatgaag tccatctttc atactttcaa
      121 ttactatcga tttttcttta tcagctaata accagtgtaa aggtgacaag ggtagttttt
      181 cactaaaatc gatattgact agattgatag tagccaataa ttctttagct tcgtctatgg
      241 ttgagcattg ccctagtatc catggaataa actcaaatgg tgcaacgtta tcttttcctt
      301 cttgtaattc tttataatca gcattgccag gaaaattcag tcctgccata ctcaaccctt
      361 tttcatttgt agcctcataa tagagtggat agttggatac cccagctgct attcctatca
      421 ttgcataatg tttatctaaa ttttttacct ttctaaaatc gaaacgataa tttcttggag
      481 taatagtgac cacttcatta taagacatct cataatcaaa attccttcca aaataatggt
      541 ctttcgttgc ataagtgatt gcggtacaca tcgtttcccc tcctaaaaca aatcgttttt
      601 acacttttat cttacatcta gtattttttt tatcaaaaaa aggccaaaga agattgattt
      661 actagcattt ataaaaaata gtactcaggg ggaatcaaaa aatattgtag gttaaaagta
      721 caacaataag gggctgtgac aaaagtcttg tcacagcccc ttattccgaa caaacggtgt
      781 tcaaaagctt gcatctgcgg taataagccc aatcaaacga aaaaatagga aaagctattt
      841 ttgtttggcc gttcttatta cttgatgcag gacagcttct tcacaacctc taatcgttga
      901 tataaggaag gtacaggatt tgaacctgcg cgccggtatt agccggttcg ccggatttcg
      961 agtccggtgc attaccactc tgccaacctt ccgtaagtac tatttttaaa cttttttcac
     1021 gaaatgtcaa gcctatttct aatagataaa taacagaaat cgcttttttt agcaaaaaag
     1081 tccattgaca gtttgcagcc aacggactta ccgatcaaat tcatactgat agaacactat
     1141 ctgattattt caggattatc taatgctaaa atcgagtcaa ttgtccgttt gatcagtgca
     1201 atgatttgtt cttctgttgg atgcatgatg tttgatgaca tcaatgacgc taagccagtc
     1261 actgctaccc atgtaccagt atgcagagca tcgacatatt catccgataa ttgattgtat
     1321 ctttcatctt ctttaactat ttcacggaaa taattgtatg aaaaatcatg cattttcttt
     1381 ccgtccccat gttcatcaat gtacaatgcc atgtaaagac tatgatgctt ttttgcaaag
     1441 tagatatagt tcaaaccgag atcaatgatt ttatcaccag tacgttcaat agggaaaaca
     1501 tcttctttta gttgttcaaa gatagaatcc agcaacgtat tttttaaatc ttccatgttt
     1561 ttgaattcca gataaatcgg ctgtgtcgaa atccccatct ttttagcaat atttctcgca
     1621 gtaaatcctt taaacccttc ctttgcaaca acatcataag cagcttttag aatttgatcc
     1681 ttggtataga cttttcttct cattaaaact cccccacttc tttactgcag tatatgttgt
     1741 tttattgtac cctattttta gcattttttg caaacatttt actcaaaacg ttatatttta
     1801 aatttttttc agtcttcttt aacttttttt tgcaaaatta aaaaaatttg gttaaattca
     1861 atgggttccc ttacattttt agttttgacc taaatgatag ttgtccaaat ctttcatttc
     1921 aagttatagt taaagaaaat gaaaaagaag gtgtgtaatg gaaaacgaaa ctgacgttat
     1981 ttatattcat cctcaaaaac gaatcgtttc acagaaaaga aagtattttt atcttggttt
     2041 tacaggtgtt ttttttcttt ttattggctt gctttctaat actcctactg ataattggag
     2101 tggattgcta actattctta cctcgccaag caatcttttg acagattatt ttgctttagg
     2161 tgttttcgga agcgcattca taaatgtagg gattttgacc ttactttctg tgcttttagc
     2221 ttatcggcac aaggtgattt taaacggtcc cttatttgct tcgattctaa cagttaccgg
     2281 tttctctttt tttggcaaaa acctttataa ttctatctca atcattttag gtgtgtatct
     2341 atacgctgta tttgtcaata aacctttttc tcagtacatc atgatcggac tgtttggtag
     2401 cgtattatca ccggtcgtta gttatatcac ttttggtatg cgttttcctt tactgatagg
     2461 tattttattg gggaatttag ctggcatagc aattggtata cttcttccgc ccttagctgc
     2521 tcaaacttta gttttccatc gtggattcac actttataat attggattca cctctgggtt
     2581 gattgcgatg acttttactg ctgttttgag gttattcagc tattcaatcg tcgaaaatac
     2641 attggttttc aatgaatatc actttcctct catttggatt atttttggct ttttttcgct
     2701 gacagtcgga attggtttct attataattc ctttcggctt tcggggattc gagaaatttt
     2761 cgattcatct ggaaaattga caactgattt cattgctaat tctggtattg gtgctacttt
     2821 gatcaacatg ggcttagttg gtctgatgct gtcttcttat gttttgctgg ttggcggtca
     2881 gttaaatgga cctgtcatcg gtgctatttt atctgcggtg ggtttcagtg cttttggttg
     2941 tcatttaaaa aacagttttc cgatactagt cggaatattt attgcttctt tgtttggaac
     3001 ttttcatgag atcaccagta ctggcatgct tgttgcagct gtgtttggga caggtcttgc
     3061 gcccataagc ggtttttacg gcagttttta cggtgtaata gctggtgtgc tacatattgc
     3121 tcttgtccat aacgtcagca ctttgcacgg aggactaaat ctatataaca gtggtttttc
     3181 aactggtttc gttgcaggta tccttgtacc gatactagat aactttaccg ctgtcagaaa
     3241 ggaaaaaaag acacttggaa aaagaattat caaaaagaat catcgatgag cttcttactt
     3301 atttatattc ccatgaaata actgaaatac gtattggagt agaatttgct gaggaagggc
     3361 ttttcataga gatacagggt acggcagaaa ctcagccaga agatttagat gtacttgctg
     3421 atttgctgaa caatcctcgg gaccctagta tggaaatcta ctatcaagaa ctattaggta
     3481 atccccgaca tgatcgggaa gattatcatc tgttaggtag tttgattgat gacgtggaaa
     3541 tcatgtatgc ccagccgatt atcaatatta agatctttcg acgtgcttct cattcctatt
     3601 attaacccta ttttctattt ataaaagact gaatcaaaaa agcagctcct gaaagttcga
     3661 ttaaaatcta ctttcaggag ctgttcaagc ttgacattat tgattttcca atccttcata
     3721 cacttcatct gttacaggtt ctaaaaactc tgaattacca gcagtgatcg ccaaatgttc
     3781 aaaccaactg tcttttgtcg caccatgcca atgtttaatc cctttgtgcg ttacgacgac
     3841 atctccagcc attaatcgtc ttgctggctt tccttcttcc tgataccagc cttctcctcc
     3901 ggtcacaagt aagatttgat agccgtctgt atggacatgc cagtgattgc gacaacctgg
     3961 ttcaaaagtt acattaccta caccaacaga aacttcggga tcattcacta acatattcag
     4021 atagctttgc ccggtaaata cttgagcgta agcttcgttt ttttcacctg ctggaaaaat
     4081 cacgccattg tgtatttctt cgtgttttgt catcatttac gcctctttct tatcttcgct
     4141 attttcttct aaatagattt cttttgctaa actaaaagct gaccaagctt ttggccattc
     4201 tacataaaaa gctaaatggg taatgatttc tgctatttct tcactagtaa tgccattttg
     4261 cttgccaatc ttcagatgag ctggcaattg ttcaaaattt cctcctgaaa ttaatgcaga
     4321 tatggtgatg atactacgct gatgagcaga taattcttct ctggaccata cttgtccaaa
     4381 taaaacatca tcatttaatt ctgcaaattt tggtgcaaaa tctcctaatt gatctcgtcc
     4441 tgcggtttgt ttttctgcca tttctcttat tctcccttca cgactgttag gtgattcaac
     4501 tatggttcta aggcaacttt attttctatt gtttcttcgc atttcatttt aaatgtagtc
     4561 tttcagcctg tccaatgctt agtttattca gtcgatatgc tttttaagca tagttgctaa
     4621 cgcttttttt attttaaaaa aaacaagtta ttaaataagt ctttagttgg atgttttttt
     4681 gagatcaatc ttttatactt atgatgaact tacaaaattg tttgttttct gtcatatcaa
     4741 aaaatggcgc agttagttgc ttttctagta aagtatagtt aacaaagaac ctctaaggag
     4801 ttgatgaata atgaatattg ctgcctctcg aaaactgata aatttcatat ccattatcgg
     4861 attaggccta tcaatcgcgc tgacgattta ttttattaat ttaggtgttt tcaaagattt
     4921 gaatgcgtta agaggattag taggtgattc catcatttta ggaccgatta tttttgtctt
     4981 catccaaatc ctgcaagtag ttattccaat cattcctgga gggatcagta ctgcagctgg
     5041 tgtcctgata tttggccctt atgctggatt tatctataac tatattggaa tctgcattgg
     5101 ttcgattatc atttttctgc tagggcgtcg ttatggaaag ccattcatac tttccatgat
     5161 tagcgataag acatataaca aatatattgg ctggctggat aatcaaaacc gttttgagaa
     5221 gctgtttgct ctagctattt ttcttccagt tgctcctgac gatgcgttat gtttgatggc
     5281 tggattgaca aacatgtcag tgaaacgata tacactaatc attttgattg ctaaaccact
     5341 gtcgattttc ttatatagta tggccttgat ttatggaggt caatatctaa gtggtcttct
     5401 tggataatat ttattttgta aaattagtca ttgattgaca atgt
//
LOCUS       DACBYO010000135         5420 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.135, whole genome shotgun sequence.
ACCESSION   DACBYO010000135 DACBYO010000000
VERSION     DACBYO010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.135"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..598
                     /locus_tag="IVD26_002750"
     CDS             <1..598
                     /locus_tag="IVD26_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP6080656.1"
                     /translation="IIETLRLENKLIYGFFDDKQNKMQDLKYLGKINELNSWADSKKK
                     IYKFIVAIGDCVVRKKIIKKLNMPSEQYGIAVHPSAIVAKEISIGYGTVIFANAVINP
                     DAVIGEHAIINTGSIVEHDCRINNYVHLSPGVCLAGGVHVGVGTQIGIGSQCIQMKKI
                     GSWCMIGAGSTIVKDIPSHSLAYGNPAKIKKEGINFEF"
     gene            588..1730
                     /locus_tag="IVD26_002751"
     CDS             588..1730
                     /locus_tag="IVD26_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAP6080657.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            1743..2720
                     /locus_tag="IVD26_002752"
     CDS             1743..2720
                     /locus_tag="IVD26_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6080658.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            2720..3628
                     /locus_tag="IVD26_002753"
     CDS             2720..3628
                     /locus_tag="IVD26_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAP6080659.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            3629..4381
                     /locus_tag="IVD26_002754"
     CDS             3629..4381
                     /locus_tag="IVD26_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAP6080660.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            4386..5333
                     /locus_tag="IVD26_002755"
     CDS             4386..5333
                     /locus_tag="IVD26_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAP6080661.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         1958 a          680 c         1043 g         1739 t
ORIGIN      
        1 cattattgaa accttaagat tagaaaataa gttaatatat ggattttttg atgataagca
       61 aaataaaatg caagatctga aatatcttgg gaaaataaac gaattgaata gctgggcgga
      121 tagcaaaaaa aaaatctata aatttattgt agctattggt gactgtgtag taagaaaaaa
      181 gattataaaa aaattgaata tgccaagtga gcaatatgga atagctgttc atccaagtgc
      241 tatagtggca aaagaaattt caattggtta tggaactgtt atttttgcga atgctgtaat
      301 taacccagat gctgtaattg gagagcatgc tataataaac acaggtagca ttgttgagca
      361 tgattgtaga attaataact atgttcattt atctccaggt gtatgcttag cgggtggagt
      421 acatgtaggt gtaggaactc aaataggaat tggttctcaa tgtatccaga tgaagaaaat
      481 tggatcttgg tgtatgatag gcgcagggag cactattgtt aaggatattc cctcacattc
      541 cttagcttat ggcaatccag ctaaaattaa gaaagaagga attaattttg aattctagaa
      601 ttttattatc aagtcctcat atgggaggaa cagaagaaaa atatgttgct aaggctttta
      661 aagataattg gatagcgcca ttaggtgaaa atgtggataa atttgaagaa agtattacaa
      721 aatatactgg ttctaagggc ggagcttctg cgttaagttc aggtacagct gccatacatc
      781 ttgccttaag actgcttaat gttggaaaaa acgatattgt ctttgctcct tcatttactt
      841 ttatagctac agtaaatcct attttatatc aaggggctgt accagtgttc attgactcag
      901 aacctaatac atggaatatg agccctgttg cactagagag cgcattagaa gaagctgaaa
      961 gaaacaacca attacctaag gcaatcatcg tagtgaattt atatggtcaa atggctgatt
     1021 atgaacgaat tttagctatt gcaaaccaat ttaatgttcc agtgatagaa gatgcagcgg
     1081 aatcgttagg ttctacttat aagggaattt cgtcaggctt atttgggaca attgggatct
     1141 attcatttaa cggtaataag atcatcacaa cctcaggtgg aggagctcta gtgtctagtg
     1201 ataaaaaata tgttgagcat tcaagatttt tagcaacaca agcaagagat caagcaccgt
     1261 attatcaaca tagcgaaata ggttataatt accgtctaag caatatttct gccggtatcg
     1321 gacgtggaca aatggaagta ttgaatgata gagtagctaa acgaagagaa attttcaatc
     1381 gatataagga agctttttct ggaattgata gaattgaaat gatgccagaa gtggatggca
     1441 tggtgccaaa tcgttggttg tctactttaa cgatcaatga ttataattct attgatcaag
     1501 tagttaacgt aataaataaa ctaaatgaaa aaaacattga aacaagagct ttgtggaaac
     1561 cactacattt gcaaccagta tttcaagggg taaaaatgta ttaccatgat aataatctta
     1621 gtgtgtcaga aaagttattt aatagcggct tatgcttacc ttctggaagt aatatgacag
     1681 atagtgaaca agaatttgtt attgatgagt ttaaaaaaat attcaagtag gtgtgatatt
     1741 ttatgaacat aggaattatt ggtttaggtt ccatggggaa aagaagactt agactcattc
     1801 aagaacactt taatgatatt ttactatgtg gtgttgatac taatgaggcg agacgaaagg
     1861 aagttgaaaa ggaatttgga ataccaactt ataatagtct aacagaggca aaaaatttgt
     1921 ttgaaataaa ttcagttttt gtttgtacat cccctataac ccatgaattt attataaaag
     1981 aggctttaaa tttagattgt aatatcttta cggaaatcaa tttattaaat gaatattatg
     2041 atgaaataat cgaagtagct aaaaagaaag atagattact ttatctatct tctacatttt
     2101 tgaagagaaa agaaattcaa tatattaagt ctaaagtgac gcataataaa aaaatttctt
     2161 atcaatacca tgtaggacag tatttacccg actggcatcc ttgggaagat tatcgcaatt
     2221 tttttgtttc aaacaaaaaa actaatgggt gtagagaaat attcgctatt gaattacctt
     2281 ggattataga tacatttggg aaagttaaat cgtttactgt aatgacccag aaattatcca
     2341 atcttgatat tgattattcg gacagtttca ctcttattat tgagcatgaa actggtatag
     2401 ttggaacttt aagtgtagat gttgtttcaa gagtagctaa aagaaattta actataattg
     2461 gtgaaaagat tttaatagaa tgggaaggta acccggattc tctattttca tggaatgaag
     2521 aaacttctag tatgacagat attcaattgt acgatgaggt tatgcatgat aataattatt
     2581 cacatactat tattgaagat gcatatttag aggagattaa agaatttttc acgcttttgg
     2641 aaaagaaaat ggaaccccaa tatacttttg aaaaagataa gtatattatt aacttaatta
     2701 acgacattga ggtaaattaa tgatgaaagt aatttttttt gggttagggt caattggaaa
     2761 gagacatcta aaaaatctaa taagctatgg aaaaaagaat tctattaatt ttgatataac
     2821 agcttatagt agcagtggaa aaaaagagtt tgaagaaata acgtatattc aaaatagaga
     2881 cgatttggat acacattatg atatagcttt tattacaaat ccgactttta agcatctgga
     2941 aacactaaat gtaattgttg aaaaagttga ttacatattt ttagaaaaac ctgctttttc
     3001 tgagagtatt gatcttactc aatataatta tgattacaaa aatatttatg ttgctgctcc
     3061 actgaggtat aaaaatatca tggaagttgt tcgtaatagt attcaaagta aaaaagtata
     3121 ttctgtaaga gctatttgtt ctacttatct tcctgattgg agaaaaggta ctgattatag
     3181 aaataattat tctgccttta aatctatggg gggaggagta gaattagact gtatacatga
     3241 attggattat attataaacc tatttggttt ccctaaatca gtaaaaaaac agtttggtaa
     3301 atattcgaat cttgaaatta acagtaatga tttagcaaca tatatattga gatacgatga
     3361 taaaattata gaaattcatt tagattattt tggaagagtt cctacaagaa aatttcaatt
     3421 gtttacttta gatgaatgta tcaatgttga cttattaaat aataaaataa gttttgaaga
     3481 aaacattgtt aaagaaatgc ctgaatctgc taatgatatg tatgagaagg agttgaaata
     3541 tttctttgaa aacgtagtaa caggcaaaga aaactggaat gatttatatc atgcaaacga
     3601 agtattgaaa atagctgagg agaaataaat ggaaatttta tttactattt gtggtagagc
     3661 tgggtctaag gggtttaaaa ataaaaattt gaaatatttg gcaggaaagc ccctagtcca
     3721 tttcgcttta gcaatgatag atatctatca acaaaaacat cctgaacata attgcacgac
     3781 ttgtttgaat acggacagta atgagttagt agaattgacg actaagttaa atccgtctgt
     3841 gaaaattgta gaacgtaaac ctgaattagc tacagatact gtagggaaaa ttgaagtgat
     3901 acgtgattca ttcttacaac tagaaagaga agataatata tttgatttaa ttatagattt
     3961 agatttgact tcacctttac gtgaagtttc taatcttgaa gaattaatag atgaacatct
     4021 aaaaaattta gataaagacg tctacttttc agttgtttct gcaagacgta atccctattt
     4081 taatatggta aaaagaattg aaaatgaagt tactatagtt aataaatcaa gatacacatc
     4141 taggcaacag acacctgaag tttttgaaat gaatgcctca atgtattctt ttaaacctga
     4201 atttctaaaa aaaagtaatt atatttttga tgggcaatgt gggataataa aaatgagaga
     4261 ttatctaatt ttagatattg atagtgaaga agattttaaa tggttagaat ttttgtttcc
     4321 taaattttta gaagattctt cggagcttca agatatctat aattatttat atcggaggta
     4381 aaaggatgag ctgttatctt atcaccggtg gggctggctt cattggttct accttagcca
     4441 atcatttagg agaagaacat gtggtaatcg tcgtcgatga cttatcaatg ggaaaagtag
     4501 aaaatcttga tatgacgaaa aatatcactt ttattgaggg agatgtcgct gagaaatcct
     4561 tgatggaaga gatcatgaaa gctaataaat ttgattatat ctttcattta gcagcagttg
     4621 ctagtgtggc agattcagtt gcccgaccag tagaaacaca tcgtgtgaat tttgaaagtg
     4681 tattaatgat tttagaattg atccgcaagt atcaacctga tttaaaacgg atcgtgttta
     4741 gttcttcagc ggctgtttat ggggatgaac cgactttacc aaaaaaagaa gagtccgtga
     4801 ttcgcccatt gacgccttat gcggttgata aattcgctgc agaacaatat gtgctagatt
     4861 attgtcattt atatgatgta cccggtagcg cagttcgttt tttcaatgtc tatggtccaa
     4921 atcaaaatcc gaattctcca tacagtggtg tgatttctat tctcgtagat cgctataaga
     4981 aacaaatcgt aggagaagca acttcattta cattatttgg tgatggaagc cagtctagag
     5041 actttgttta tatagatgat gtaatccaag cattactttt agttgcgaat gaggaagctg
     5101 cactggggaa acaattcaat gttggaacgg gtaaagcaac cacacttttg gaattgattc
     5161 atgcaatcaa tgaaattctc ggtgtagaat tgacacttga atacaaagaa gagcgttcgg
     5221 gtgatatcca tgactctcta gcagatatta ctaagatcca gtcaattggc tatcaaccga
     5281 aatatggtat tttaagtgga atgactaatt atttgaaaac tgaaatcaat taaaacatac
     5341 taagataaga ttagagggta aattcaggct ctttgtcaat aaggactgat gagttttgta
     5401 aaatcaaatc tgggatagaa
//
LOCUS       DACBYO010000136         5176 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.136, whole genome shotgun sequence.
ACCESSION   DACBYO010000136 DACBYO010000000
VERSION     DACBYO010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.136"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(136..1098)
                     /locus_tag="IVD26_002756"
     CDS             complement(136..1098)
                     /locus_tag="IVD26_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6080662.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1100..2539)
                     /locus_tag="IVD26_002757"
     CDS             complement(1100..2539)
                     /locus_tag="IVD26_002757"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HAP6080663.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2724..4670
                     /locus_tag="IVD26_002758"
     CDS             2724..4670
                     /locus_tag="IVD26_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HAP6080664.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            4934..>5176
                     /locus_tag="IVD26_002759"
     CDS             4934..>5176
                     /locus_tag="IVD26_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6080665.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPK"
BASE COUNT         1666 a          878 c          855 g         1777 t
ORIGIN      
        1 tttctccact ccaaaaaagt ctaacttttg ggggtcacta caagttgaca actccttttt
       61 gtttacaaat caattggata tctacaaatt gtattttcta acgaatttta tagacattaa
      121 aaaattaatt taacgttaaa tacttcctcc agaaagtatt gagattggta aaatataatc
      181 cttatttgtc ttttcgcctt taattttttt cagaagaata tcaacaataa gacttgcaat
      241 ttcatcaatt ggttgtctta ttgttgtcaa ttgtgggaaa aatttctcaa taaaagaggt
      301 accatcgtat ccaataattt ttaaatcttc tgggatatta agtttaagtt gatgagcaat
      361 tttcatagtg agaatggctg ttaaatcatc agaaacaaaa ataccatctg gtttgtgatt
      421 tataatagtt gactttattt ccatttcacg acggatagta gacagattat taggaatttt
      481 gaaaattttt ccatttggat tttgaaaaga aaaacctagt gcacgtaatt ctgtgggaga
      541 atccgtgtta tcatttcctg taatcataat ggtattttga caaccatttt tttgtaaagt
      601 cttagctgca agttttcccc cttcaaagtt atctgaagaa acaatggaaa cattaggagc
      661 taaatttcta tcaaaagcaa caataggtgc tctcacacgc tcataatcag caattccaag
      721 attatggctt gatgagatta tgccatcaac ttggttggct tcaagcattt caatgtattc
      781 tctctcttta gcaggatcat tttgactatt gcaaataatc gttttatatc catgtttaaa
      841 taactctatt tcgagatact caatgagttc agagtaaaag atattactaa tattaggaaa
      901 aataagacca ataagctgag gtgactttcc ttgaagtcca cgtgctaaat tatttggttt
      961 ataaccaaga gttttcatag cttcatgaac tttttgtttt gttttttctg ataaatatcc
     1021 cttattatta atgacgcgtg aaacggttgt tgggctaact ccagctaatt cagcgacatc
     1081 agttaatttt gctaccattt taatatttta attcaaagta ttttccagta ggttcgcctg
     1141 atttgatttg aataccattt tggtgatttt cagggaatac acgactagta aacacttttt
     1201 ctcctttatt aataaaaatc tcaatgattg agttatctac aaaaatgtta gcagttgttt
     1261 ctttagtatc aattgagcat tcacgaatcg taccaaagtc agtggcatat tgaatgcctg
     1321 ctttgctgcg atctaaaata atttttcctt ctttggtatc tacaatcaag ctaagtccat
     1381 ttcctttact atcagagaaa agaagtaact ccgatttctg atttggagga aaagttagtt
     1441 caagctcata agtattattt gtttctgctt ttgctgtaaa ttgttcagaa ctagcacgta
     1501 atgatgtaat agcttctact ggatattggt aaagtttacc atcttttatt gaaagttctt
     1561 ttacaagact cattgctccc tgataatcat acttatcagt tggataatcg atatcaggta
     1621 gtccaatcca actgacaatc agagcacgac catcaggagt attgaatcct tgagtcgcat
     1681 acgcttcaaa tccataatca agattttgaa tttctgaagc gcccacaagt tttacttttt
     1741 ctatgtcaag cgattgacag atcttaaaag tattcggata gatattccca taatttagct
     1801 cagatttatc caacccttga ggacaataaa tgagaacagg ttttttgtct acaaatacta
     1861 gatttggaca ctcaatcatg tattctgaac cagtgccgcc aaaatcaagg ttgccaactt
     1921 cctcccatgt ttccacgtta ttgtcatccg ctttgtaaag tttgataaag cctgattttt
     1981 ctaaattttg tgctccaaca atcgcataca attgtccttc ataattaaac atttgtggat
     2041 cacgaaaatg atcagttaca tcagcaggtt tatgaataag aacattctca cctttcgtaa
     2101 tgttgtagtc tttatccatc catgctccga tttgaagtgt atcacgttcc caattttcat
     2161 ttcgaacgtt tcctgtatag agtaagaata gattcccctc tatttcatat gcagaaccgg
     2221 aataagcgcc gtggctatct cgttttgtgt ctggaagaag ttctgctcct gttacatgaa
     2281 aatgaactaa atcatctgat tcattgtgta cccattcttt caacccatga gcagctccaa
     2341 atggccaatt ttgataaaaa agcgtatatt ttccgttaaa aaaagaaaaa ccattaggat
     2401 cgtttaacaa tcctgtttta ggttcgatat gatagctagc acgccaaggt gatcgtttta
     2461 cattatcctt aattttatcc atctcatctt tagtccaatc agaataagca cgatatcgta
     2521 tttctcgagg taagttcata ttttactcct tcaatttatc tttttacaac tagtatggta
     2581 aacgttttcc gttgaaaaat caatcatttc atttaaaaaa ataaactata tgacaaacgt
     2641 ttgacatatt tttaagatat gctaaaataa atttgcattt cagtgaaccg ttttcacgta
     2701 aaaataaaaa aggagtgatt cgaatgaatt acagtaaagt agcttccgac gtaatacaag
     2761 cggtcggaaa agataacctt attgcagctg cacactgcgc tacacgtctt cgtctcgtac
     2821 taaaagatga cacgaaagtg aatcaaaaag ctttagacga aaatccagat gtgaaaggca
     2881 catttaaaat tgatggacaa tatcaagtga ttatcggtgc aggtgatgtt aatttcgttt
     2941 atgacgaact tatcaaaaaa actggacttt cggaaatttc aacagatgat ttaaaacaaa
     3001 ttgctagtaa agataaaaaa ttcaacccca ttatggcatt aattaaatta ttatcagata
     3061 tttttgttcc aattatacct gcccttgttg caggtggttt attaatggca ttacaaaact
     3121 ttttaacagc tgctggactt tttggaccaa aatcaattga agaaatgtat cctgcgattg
     3181 aaggtatttc ctcaatgatc caactgatgt ccgctgcacc attcatgttc ttaccaattt
     3241 tagtaggtat ttcagctgct aaacgttttg gagcaaacca atttcttggt gctgcaattg
     3301 gtatgatcat gacaacacca gatcttggtg gctcaactga atattggaat atttttggtt
     3361 atcatgtttc acaaacaaac tatgcttatc aagttattcc agttttagca gctgtttgga
     3421 tattatctat attagaaaaa ttctttcata aaaaattgcc atcatctatt gactttacat
     3481 tcacgccatt attatcagta atgattactg gatttttgac tttcacagtt attggccctg
     3541 taatgttatt gttgtctaat ggaattacag acattattgt ttggctatat aacactactg
     3601 gatttattgg aatgggtatt tttggaggaa catattcact tatagtcatg actggtttac
     3661 atcaatcatt tccagctatt gaaactcaat tactttcagc gtggacaaat ggtatcggac
     3721 atggagactt tatctttgta gttgcatcta tggcaaacgt tgctcaaggt gctgcaacat
     3781 ttgccatttg gttcttaact aaaaattcta agacaaaaag tcttgcttcc tctgcgggtg
     3841 tctcagcact tcttggaatt acagagcctg ccttgttcgg agttaactta aaataccgct
     3901 ttccattctt ttgtgcttta attggttcag gaattgctac agcagtagca ggattactta
     3961 aagtagttgc tgtttcactt ggttcagcag gtttcttggg atttctttca attaatgcaa
     4021 catctattcc attttacgta ttgtgtgaat tgattagctt tgtagttgct tttgcaatta
     4081 cttacttcta cggtaaaaca aaagctgctg gtatctttaa agcagaagaa attgctgaac
     4141 aaacaccagt taattcttca aaagtagcaa caacagatcc aatatctact gatgttgaat
     4201 caacacaaac aaaagtttca tcagaaacaa ttgttagtcc catttctggt aaagtgatta
     4261 gtctttcttc agtaaatgat ccagtctttt catcagaagc tatgggaaaa gggattgcca
     4321 ttaaaccaaa tggaaacacg gtccattctc cagtagatgg tactattcaa ctcacgtttg
     4381 aaactggaca tgcttatggt attaaatcaa ataatggtgc tgaagttcta attcatattg
     4441 gtattgatac tgtatcaatg ggaggaaaag gatttacaca aaaagttact actaatcaaa
     4501 aagttagaaa aggcgatatt cttggagcat ttgaccgttc aatgattgag aaagaaggtc
     4561 ttgatgatac aacaatgatt attgtgacca atacttcgga ttattcagaa gtaaatatag
     4621 tagctgaaaa tacagtcact gagggtactg atttacttga aatcaaataa atatatttcc
     4681 ctgagtaaag atggaatttt ctttccaaaa tcaaataata tagattaatc aaatatttga
     4741 gaataacatt ttatttaatc ttttcatata tcaattgtat gaaaaattat tagaatttta
     4801 aaaaatgata aaaattcaaa aagaaaaaat agtagttatt tacttgtcat gttactaaat
     4861 aaaaaaataa tttaaatatg atatatagtc atttatttag tgatttcatt ctaaaataaa
     4921 gggagaaatg tctatgctat acggtgcaat tgaagcaggc ggcacaaaat ttgtgtgtgc
     4981 cattggcgat gaagaaatga cgatcaagga aagagtgagc tttccgacaa cgacacctga
     5041 ggaaacaatg cctttagtca ttgacttctt caaacaatac caagcagatt tagcagggat
     5101 tgggattggc tcatttgggc ctatcgatat ccatcgcgat tccgccactt atgggtacat
     5161 tacctcgacc ccgaaa
//
LOCUS       DACBYO010000137         5087 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.137, whole genome shotgun sequence.
ACCESSION   DACBYO010000137 DACBYO010000000
VERSION     DACBYO010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.137"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="IVD26_002760"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="IVD26_002760"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HAP6080666.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="IVD26_002761"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="IVD26_002761"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HAP6080667.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="IVD26_002762"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="IVD26_002762"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018593001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HAP6080668.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="IVD26_002763"
     CDS             complement(4028..5044)
                     /locus_tag="IVD26_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP6080669.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
BASE COUNT         1337 a         1270 c          909 g         1571 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaa
//
LOCUS       DACBYO010000138         4934 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.138, whole genome shotgun sequence.
ACCESSION   DACBYO010000138 DACBYO010000000
VERSION     DACBYO010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.138"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            209..1009
                     /locus_tag="IVD26_002764"
     CDS             209..1009
                     /locus_tag="IVD26_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP6080670.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            1028..2896
                     /locus_tag="IVD26_002765"
     CDS             1028..2896
                     /locus_tag="IVD26_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP6080671.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            2889..3380
                     /locus_tag="IVD26_002766"
     CDS             2889..3380
                     /locus_tag="IVD26_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAP6080672.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            3368..3922
                     /gene="srlA"
                     /locus_tag="IVD26_002767"
     CDS             3368..3922
                     /gene="srlA"
                     /locus_tag="IVD26_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAP6080673.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            3940..>4934
                     /locus_tag="IVD26_002768"
     CDS             3940..>4934
                     /locus_tag="IVD26_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAP6080674.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         1724 a          769 c         1034 g         1407 t
ORIGIN      
        1 ttaaatgata aaacaattat atatcaaaaa gagaaacatt gcttatataa cgctcaggaa
       61 ttttagcaat ctatgcaaaa agatgaaaat tttttttgct cttccattag tacacatttt
      121 ttagctgaag ctgtaaattt catgtcttaa ttttttttag tgagctttta tactggattt
      181 gtaagaaaaa agaaggagag gatcacatat gtcggattgg ttggatattg caggaaaagt
      241 agtaattgta actggaggtt cctcaggaat tggaagaagt atcgtcgaaa atttgttgaa
      301 gcagaatgca caagtagcga attttgatgt aactgaatgc cgtatacagc atgaaaacct
      361 actatcttta aaagtcgatg tgtcttctaa aacggacata gaagaaggga tatataaagt
      421 aatgaaacat ttcaagacga tcgatggtct agtcaataat gcaggaataa atattccttc
      481 tcttctaata gatagaaatc atccaaaaag caagtatgaa ttatcagaac aagtttttga
      541 taagatgatc gctgtcaatc aaaaaagtgt atatttgatg agccaagcag ttggaagaat
      601 cttggtgcaa aagggatcag gagtgatcgt gaatctttct tctgaatcag gattggaagg
      661 atcagaagga cagagctgtt atgctgctac aaaagcagcg atgaacagtt ttactcgttc
      721 ttgggcaaaa gagttaggaa agaggaatgt tcgtgtggta ggtgttgcac cagggatact
      781 ggaagaaacc ggtttgagaa cacaagaata tgaagaagct ctttcttata cgagaggtat
      841 aagcgtcgaa cagctgagaa acggttacag tcgaacaagt acgatccctc taggaaggag
      901 tggtaagctg caagaagtgg cggatctagt ctgctattat ctttcagaaa gatcaagtta
      961 tatcactgga gtcacgacta atatttcagg aggtaaaaca agaggataaa ggataggggg
     1021 gacgcacgtg acgctagtaa acagatggta ccaattattg aaattactag tcactcacaa
     1081 gaaagtttca atccaggaag tgcaaaaaga aatcaaaacc agtaatcaaa ccataaaaaa
     1141 agatattggg gagttgaatg aagaaattgc cggtattgca aaaatcatcc aaaaaaacaa
     1201 acattttgaa cttgaaattt atgattttga tttttttgat gagatcatgc aaggaaaatt
     1261 gaaaacagcc agtgatttca attcggcatc caaaagaatc gcttatttac taaataggct
     1321 gatcgaaaca gaggatttct tacgtatgga tgatttgtct gaagaagtcg gtgtcagcag
     1381 aggaacagtg gtcaaggatc taaagacatt aaaagagatg atcaatgatt ttgatgtaaa
     1441 gattacaggc acaccaaata aaggactaag aataatagga gatgagctag aattacgact
     1501 acttttattt tattttgttt ctccctactt ttcagagacg aaaacagaac agtttctaga
     1561 agaaaaacaa gcaatcaaac attttcagaa gaagacgaat gctagtaaac aagaaatcac
     1621 ccttttaacg aaagttatcg gtatttcttt gaatagaatc tctagtaact atctgttgaa
     1681 gaagcccatc aatcgttaca gtgggtgttt tgaatatatc caagaattca atgaactgat
     1741 caatcagttg gaagaaatct atgaactaac tttgagccaa tatgaaaaag attttatcag
     1801 ttttcctttg aacatcatca acacaagtat aacgatgata aggaaagcta actctgattt
     1861 gcgcttatat ttcgacccca tgatgatgcg tattcgacga ttagatctca ttgatctgga
     1921 tgagtccttc ttatatcaag agatgaaaca gcacctctct ttattgataa atcgggtaat
     1981 ttttcgttat cgattgactg atttatttta tggtgagata gaaaaaaagt atcctttttc
     2041 ttaccaaatc gctagcgaat gcatacaagc attagaagct atcttgcaac ataagatctc
     2101 taaagtagag atcagctacc taacgttgta tttggagtta gcatttcgat atcaaaaaga
     2161 gcatttttcc tctaaaaaag tagccattgt tcatacgaca ggaaaaggaa cagcattaat
     2221 gatccaaaga caaatcaaaa ggatattggg gagggatata caaataacac atgtttcaga
     2281 agaacaatat gaaaaagtag atctaaacaa atatttcgct gtttttacaa cgattccgtt
     2341 aaaaaatgta aatgaagaga caccggtgat ccatttgact aatctttttg atgactcttg
     2401 gttaagggca caatggcaaa aagcaaaaaa aaagcgatta gccgggtttc attctactgt
     2461 ttttttctat caaatatgga aagaaaaaaa gacgtatcaa gaatatttaa acaaattagt
     2521 cgctcctttg atcagaggct attatgtgga tgaagaattt gaaaaaagga tcttgaaaag
     2581 agaatatcag caaagcacat ttgttaacaa agaatttgct tttcctcaca caaccaacca
     2641 gctatctcaa cacattgttt tatcagtagg gctaataact gatcaaggtt tagcagaaac
     2701 aggaggaaat ggagttattt ttttatttgc catacctgaa gaaatgacgg ctgaagttga
     2761 gaatgaatta tttgagctat acgatatcct atttgaactc ataaaaatgg gaatagatga
     2821 gtttattgaa ttagcaccga cacaagaatc atttttaaaa ctaatcaaaa gtaaaggaga
     2881 gagacttcat gaatgatatg tatctattca tagttttcgc agcttcagct tatgtgctgc
     2941 aagcagttat cagttggaag caactaaagc atttcaatca aacatatagc gaactgcgaa
     3001 gaaaaggaaa agtagcgatt ggtaaacgac ctgggaaaat ccgttcaggc acgattgtta
     3061 tgctagctat agacgatcat gatcaagttt tagaagtcag aaaaatgcaa ggggttacat
     3121 ctttggcaaa atttcattca ttacctgtct atgcgggtga agatatccat tacatcgatc
     3181 gttaccatcc ctcagttcga gcggaagatc gtttgacaca agcagcttta gaaaatgcca
     3241 gagaagtata cttacgaata gaggcaggaa atgaaaaaag tgaacaacct tcattgcctt
     3301 ttattgctat gctcaataat tttcggatat ggaaaagtac gatcaaagaa aaaaggagtg
     3361 acaaacgatg gatatcataa caaaatttgc tgagggattt atgaggctgt tccaaacagg
     3421 tgcagaaaca ttcataagct ggatgacagg aatcgtacca gttgtcttga tgctgatggt
     3481 tgcaatgaat acgctgattg cttttttagg tgaagaccga gtaacgaaag tagccaaatt
     3541 atcagcgaaa aatccgctta ctcgttacct tgtgttaccg ttcttatctg cttttatgtt
     3601 gggaaatcct atgtcattta caatggctcg tttccttcca gaatactaca aaccaagcta
     3661 ttatgctgct caagctcaat tttgtcatac gagcaatggt gtattccccc atattaatcc
     3721 tggagaattg tttgtatgga tggggattgc tcaagggatc gaaaccttag ggctaaattc
     3781 gatggagctg gctatccgat acttgcttgt gggactgctg atgaacttta ttggtggttg
     3841 gataactgat tttactactg gatttgtatg cagacagcaa ggaatcgttc ttagcaaaaa
     3901 agtagagctt tcagttgatt agagaaagga gagttttaaa tgtatggtga tattaagatc
     3961 gtaagaggaa acggcgggta tggaggtcct ttgattatta ggccgacaaa agataaacac
     4021 aagttcatct atgtcacagg tggaggtgag aggccaatga tcgtagataa aatagaagaa
     4081 ctgacaggta tggagtctat caatgggttc aaaacatcaa tacctgatag tgaaatcgcg
     4141 cttgcaatcg ttgactgtgg agggactctt agatgtggaa tttatcctaa aaaagggata
     4201 ccaaccatca atatcgtttc cacaggaaaa agtggcccat tagcacaata tatcactgaa
     4261 gatatttatg tttcagcagt agggttagaa caaatacagc cactaatgga aactgatgat
     4321 aacaaagaaa cagtaaatac tgcatctcca gataaaaagt acaaatatga tacttctaaa
     4381 aagataaccg agcaaaaagc agagcagcaa aactggatag caaaaattgg aatgggcgcg
     4441 ggaaaagtag ttgctacatt caatcaatca gcaagagaag cagtagatac gatgatccgg
     4501 acagtgatcc cttttatggc tttcgtttcc cttttgattg gtgtgataca aggttctggg
     4561 atcggtaatg tatttgctaa cattatggca cctttagcag gaaatgcagt tggattaaca
     4621 atcattggct ttatttgttc actgccattt ttatctcctt tgcttggtcc aggggcagtt
     4681 attagccaag tgattggaac attgatcggt gtagagattg ggaaaggaaa tattcctccc
     4741 caattagcat taccggcact atttgctatc aatactcaaa atgcatgtga ttttattcca
     4801 gtcggtctag gtttggaaga agcaaaagct gagacagtag aagtaggtgt accatcagtt
     4861 ctttattcaa gatttcttaa cggcatccca cgagttatca ttgcttgggt agcaagtttt
     4921 ggattatata gctg
//
LOCUS       DACBYO010000139         4931 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.139, whole genome shotgun sequence.
ACCESSION   DACBYO010000139 DACBYO010000000
VERSION     DACBYO010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.139"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            85..972
                     /locus_tag="IVD26_002769"
     CDS             85..972
                     /locus_tag="IVD26_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP6080675.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="IVD26_002770"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="IVD26_002770"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAP6080676.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="IVD26_002771"
     CDS             2274..2720
                     /locus_tag="IVD26_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP6080677.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="IVD26_002772"
     CDS             2993..4345
                     /locus_tag="IVD26_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAP6080678.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="IVD26_002773"
     CDS             4516..4803
                     /locus_tag="IVD26_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080679.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1393 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt t
//
LOCUS       DACBYO010000140         4726 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.140, whole genome shotgun sequence.
ACCESSION   DACBYO010000140 DACBYO010000000
VERSION     DACBYO010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.140"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            138..945
                     /gene="vanY"
                     /locus_tag="IVD26_002774"
                     /pseudo
     CDS             138..945
                     /gene="vanY"
                     /locus_tag="IVD26_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-B/VanY-G family D-Ala-D-Ala
                     carboxypeptidase"
     gene            963..1790
                     /gene="vanW"
                     /locus_tag="IVD26_002775"
     CDS             963..1790
                     /gene="vanW"
                     /locus_tag="IVD26_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HAP6080680.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGEPFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            1787..2758
                     /locus_tag="IVD26_002776"
     CDS             1787..2758
                     /locus_tag="IVD26_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HAP6080681.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2751..3779
                     /gene="vanB"
                     /locus_tag="IVD26_002777"
     CDS             2751..3779
                     /gene="vanB"
                     /locus_tag="IVD26_002777"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HAP6080682.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGTFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3785..4393
                     /locus_tag="IVD26_002778"
     CDS             3785..4393
                     /locus_tag="IVD26_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HAP6080683.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
BASE COUNT         1326 a         1003 c         1259 g         1138 t
ORIGIN      
        1 tataaccctg ccggtctttt tttgctgcta caggaaaact acagactggc tacagggaaa
       61 gtacagatgc gcttgccata ataacaatcg taccagccac aaatcgtagt tttattgcaa
      121 aggaggcatt cgatcaaatg gaaaaaagca actatcattc caatgcggat catcacaaac
      181 ggcatatgaa acaatccgtg gaaaagcggg cttttctatg tgcgttcatt atttcgttca
      241 cagtctgcac gctgtttttg ggggcggaga ctggcttccg tattggaggc aacacagata
      301 ccgcccatcc ctgcaactca tacaggcagc agcactgacg tagtggagaa tttggaggaa
      361 aacgctcttg ccaccgccaa agaacaggga gatgaacagg aatggagcct gattttagtg
      421 aacaggcaga accccatccc cgcacagtac gatgtggagc ttgagcaact atcaaatggt
      481 gagcggatag atattcggat ttctccctat cttcaagatt tgtttgatgc cgcaagaact
      541 gatggagttt acccgattgt cgcatccgga taccgaacaa cagaaaaaca gcaagaaatt
      601 atggatgaaa aaattgccga atataaggcg aaaggctaca cctctgcaca ggctaaagcg
      661 gaagcagaaa cttgggtggc cgtgccggga acgagcgagc atcagcttgg tcttgctgtg
      721 gatatcaatg cggacggaat tcattcaaca ggcaacgagg tttatagatg gctggatgaa
      781 aacagctatc gttttggttt tattcgtcgc tacccaccag acaagacaga gataaccggt
      841 gtgagcaacg agccgtggca ttaccgatat gttggcatcg aagctgccac agagatgtac
      901 aaccaagggg tttgccttga ggaatattta aaaccagaaa aatgagaaaa ggatgttatg
      961 ttatggacag aaaaagattg acacagcgtt tcccgttcct gcttccaatg agacgggcgc
     1021 agagaaaaat gtgcttttat gcgggaatga gatttgacgg ctgtcgctat gcgcagacga
     1081 taggggaaaa atcgctttcc catttgctct ttgaaacgga ttgcgcatta tacaaccaca
     1141 ataccggatt tgacatgata taccaggaaa acaaggtgtt caacttaaag ctggcagcaa
     1201 agaccttaaa cggcttattg ataagaccgg gggaaccctt ttctttctgg tggctggtac
     1261 gccatgcgga caaagatacc ccctataaag acggccttac ggtgaccaat ggtaaactca
     1321 ccaccatgtc gggcggcggt atgtgccaga tgagcaattt actattttgg atgttcctgc
     1381 atacgccatt gacaattatc cagcgcagag gtcacgaagt aaaggagttt ccagagccaa
     1441 acagtgacga gattaaaggg gtggatgcaa ccatttcaga gggctggatt gatttaaaag
     1501 tgcgaaacga taccgactgc acctaccaaa tatgggtgac cttagatgat gagaaaatca
     1561 tcggtcaggt gtccgccgac aaagagcccc aagcattata caaaattaca aatggcagta
     1621 tccagtatgt ccgtgaaagt ggcgggattt atgaatatgc ccaggttaaa cggatgcaag
     1681 ttgccttagg taccggggaa ataatagatt gcaagctgct ttatacaaac aaatgcaaaa
     1741 tctgttatcc cctcccggaa agtgtggata ttcaggagga gaaccaatga gaaaaagtgt
     1801 gggcattact gtttttggat gcgaacagga tgaggcaaat gctttccgcg ctttatcgcc
     1861 ggattttcat attatcccta cgctgattag cgatgcgata tcggcagaca acgcaaaatt
     1921 ggccgctggc aatcaatgcg ttagcgtagg ccataagtcc gaggtttccg aggcgacaat
     1981 tcttgcgctg agaaaggtcg gggtaaaata catttctacc cgcagcatcg gctgcgatca
     2041 cattgatacg actgccgccg agagaatggg aatctcggtt ggcacggttg cgtattcgcc
     2101 ggacagcgtt gcggattatg ctttgatgct gatgctgatg gccatacggg gtgcaaaacc
     2161 caccatgcac gccgtggcgc aacaagattt cagattggat cgtatccggg ggaaagaact
     2221 gggggatatg actgtgggag ttattggaac cggccatatc gggcaagcgg tcgtcaaaag
     2281 gctgcgggga tttggatgcc atgtgctggc ctatgataac agccgaaaaa tggatgcaga
     2341 ttatgtccag cttgatgagc ttctaaaaaa cagcgatatt gttacgctcc atgtgccgct
     2401 ttgtgcggat acccgccatc tgatcggtca gaagcaaatt ggagagatga agcaaggcgc
     2461 atttttaatc aacaccgggc gcggagcgct tgtcgatacc ggggcgctgg tggaggcgtt
     2521 ggaaagcgga aagctgggtg gtgcggcact ggatgtgttg gagggcgagg atcagtttgt
     2581 ttataccgat tgctcgcaga aagtgcttga ccatcccttt ttgtcgcagc ttttaaggat
     2641 gccgaatgtg atcatcacac cccatacggc gtactacact gagcgtgtgc tgcaggatac
     2701 tacagaaaaa acaatcagga attgtctcaa ttttgaaagg agtttacagc atgaatagaa
     2761 taaaagtcgc aatcatcttc ggcggttgct cggaggaaca tgatgtgtcg gtaaaatccg
     2821 caatagaaat tgctgcgaac attgatacgg aaaaattcga tccgcactac atcggaatta
     2881 caaaaaacgg tgtatggaag ctatgcaaga agccatgtac ggaatgggaa gccgacagtc
     2941 tccccgccat actctccccg gataggaaaa cgcatgggct gcttgtcatg aaagaaagcg
     3001 aatacgaaac acggcgtatt gatgtggctt tcccggtttt gcatggcaaa tgcggggagg
     3061 atggtgcgat acaggggctg tttgtattgt ctggtatccc ctatgtgggc tgtgatattc
     3121 aaagctccgc agcttgcatg gacaaatcac tggcctacat tcttacaaaa aatgcgggca
     3181 tcgccgttcc cgaatttcaa atgattgata aaggtgacaa gccggaggcg ggtgcgctta
     3241 cctaccctgt ctttgtgaag ccggcacggt caggttcgtc ctttggcgta accaaagtaa
     3301 acggtacgga agaacttaac gctgcgatag aagcggcagg acaatatgat ggaaaaatct
     3361 taattgagca agcgatttcg ggctgtgagg tcgggtgtgc ggtcatgggg aacgaggatg
     3421 atttgattgt cggcgaagtg gatcaaatcc ggctgagcca cggtaccttc cgcatccatc
     3481 aggaaaacga gccggaaaaa ggctcagaaa atgcgatgat tacagttccc gcagacattc
     3541 cggtcgagga acgaaatcgg gtgcaggaaa cggcaaagaa agtatatcgg gtgcttggat
     3601 gcagagggct tgcccgtgtt gatctttttt tgcaggagga tggcggcatc gttctaaatg
     3661 aggtcaatac cctgcccggt tttacatcgt acagccgcta cccacgtatg atggccgccg
     3721 caggaatcac gcttcctgca ctgattgaca gcctgattac attggcgtta aagaggtgat
     3781 aagtatggaa aatggttttt tgtttttaga tgaaatgttg catggcgtcc gttgggatgc
     3841 caagtacgcc acatgggata acttcacagg aaaaccggtg gatgggtatg aggtgaatcg
     3901 catcatcggc acaaaggccg tggcgtttgc tctgcgcgag gcacaaatcc atgcggctgc
     3961 gcttggctat ggcttgcttt tatgggatgg atatcggcca agaactgcgg tggactgctt
     4021 cctgcgttgg gcagcgcaac cggaggacaa tctcacaaaa gaaaaatttt accccaatat
     4081 agagcgagcc gagttgatta caaagggtta tgtggcctca caatccagcc atagccgtgg
     4141 aagcgcaatt gatcttacgc tctaccacct ggatacaggg gaacttgttt caatgggaag
     4201 taacttcgat tttatggacg aacggtcgca tcatacagca aaagggatag gggatgcaga
     4261 ggcacaaaat cgaagatgct tgcgtaaaat catggaaagc agcggatttc agtcttatcg
     4321 ctttgaatgg tggcactata agttgattga tgagccatac cccgatacct attttaattt
     4381 tgccgtttca taatgaaagt attggttttg tatcagattt tggatttgat aaaatctatg
     4441 ctggtcatgg acaatctttt actggaaagt ggttaaagca tcttttgtaa tacattgcaa
     4501 attatagtat tcaatctgcc cagcggcaga aaagaaaaaa accgctgttg ggcagacctt
     4561 tcccacgccc attttgtatt ttgctggcgg cggttttgag aaatcaaggc cgccgttctt
     4621 ttctggcagc aaaaggtgtg gcggcccata ggaggatgcc gctatgctgt tttgctattg
     4681 ccatgctcta atccacttcc accactcaaa aaaagccttg cccctc
//
LOCUS       DACBYO010000141         4620 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.141, whole genome shotgun sequence.
ACCESSION   DACBYO010000141 DACBYO010000000
VERSION     DACBYO010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.141"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(99..1073)
                     /gene="lacD"
                     /locus_tag="IVD26_002779"
     CDS             complement(99..1073)
                     /gene="lacD"
                     /locus_tag="IVD26_002779"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAP6080684.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDAKMPGR
                     LPDLLNSWSVKRLKEVGADACKFLLYYDVDEPVEINVQKQIVIERIGSECEAEGIPFF
                     LELLSYDATIGDPSSLDYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QDTCYSQAEASAYFYEQSKVTEQPFIFLSAGVSAALFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATSIYVNK"
     gene            complement(1070..1528)
                     /locus_tag="IVD26_002780"
     CDS             complement(1070..1528)
                     /locus_tag="IVD26_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP6080685.1"
                     /translation="MTIIHEENIFLQQPLDNQEEAFKFLAKQTFCLGIAHDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSLIIVTLKKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRAAKSKIEIATILTKEIGEDI"
     gene            complement(1525..2988)
                     /locus_tag="IVD26_002781"
     CDS             complement(1525..2988)
                     /locus_tag="IVD26_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP6080686.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFVGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSSDPDHAQYNATAAMVKAVDDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLIILPKQLDGLKAIVLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEYSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLTQGN
                     TTFMAGASAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKRDNKATNRTVIEEGRAGGLS"
     gene            complement(2970..3902)
                     /gene="pfkB"
                     /locus_tag="IVD26_002782"
     CDS             complement(2970..3902)
                     /gene="pfkB"
                     /locus_tag="IVD26_002782"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAP6080687.1"
                     /translation="MSIYTCTMNLAIDLFIETDEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAGDYLCVSGSLPRGLSPKVLIEISRICLIIDS
                     SDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENVLLSLGE
                     KGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLAGYMNRRSLDETLRKSIAAGSS
                     TAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            4044..>4620
                     /locus_tag="IVD26_002783"
     CDS             4044..>4620
                     /locus_tag="IVD26_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP6080688.1"
                     /translation="MNHKLSETEQYLWNFIEHLILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGEKTNKNIKNKIYVFIFQFFK"
BASE COUNT         1383 a         1032 c          730 g         1475 t
ORIGIN      
        1 acttttgcag ttttatactt tttttctata aaatttgaca aacatttttt taaataacta
       61 attatttttt gaatctgtca ctcagacaat cctttctctt acttgttaac ataaatagaa
      121 gttgctgttt cttctaatag tgtacttaat tctttaatat tttgttttcc ttcttctaac
      181 atccaactac tcgctttttc ttcgccttcg gtaacaaaag gtgctactcc cttcgcccat
      241 gttgctcgcc cacataagac accattgaat gtcgaacctg attgttttgc aaaacgcaat
      301 gtatcttgaa atagtgcagc gctgactccc gcacttaaaa aaataaacgg ttgttcagtc
      361 actttcgatt gttcatagaa atacgcggat gcctctgctt gactataaca agtatcttgc
      421 ccatatcctt ccacaaatct catattcact ggtacttcta ctttcaatac atccacttga
      481 taacgttctt ttgaaaattc tcgcatggct tcaatcactt tatgcggttt tacttttgca
      541 tagtcaagag aagacggatc gccaatagtt gcatcgtaag aaaggagctc taaaaagaaa
      601 ggtatgcctt ctgcttcgca ttctgaacca atccgttcta taactatttg tttttgcaca
      661 ttaatctcta ctggttcatc aacgtcatag tacaataaaa atttacaagc atccgcaccc
      721 acttctttta accttttcac tgaccaacta ttcagtaaat ctggtagtcg gcctggcatt
      781 ttcgcatcat agccggtttt ttcataagct agcaacaaac cacattcttt ctctcgaagc
      841 gctgctgcag gcagaccata ttctggatcg agtaaaatag cggaagcata cggagtcagg
      901 tactgagaaa ccatctgttt aaattggatg atatcttctg atgtagcttc tttatattgg
      961 ttgatcattt tcttcaaagc accacgttgg tcgatagcta gcgcgctaat aattccagct
     1021 tcatccgtca atcgcttcaa acgttcctgt ttttctatac tcattttctt catatatctt
     1081 cacctatttc tttagttaat attgtagcta tttctatttt tgattttgca gctctcaact
     1141 gttctgtaac ctcttttcgc atcaatgatc gtgcaacgag agacaataat ttcaaatgag
     1201 tcgttcctgc ttctgaatct gggataaata acgcaaaaat aaaatcaact gactgtctat
     1261 ctaaactgtt ccattcaatt ccttttttca gtgtgacgat aatcaaacta ggttcattga
     1321 ttgtttgaga cttcgcatga gggatagcaa aacctgacat tattcctgta gtaccttctt
     1381 tttctctttc cagaagtttt tgatatactt ctttttcgtc atgagcgatt cctaaacaga
     1441 atgtttgctt tgctaaaaac ttaaatgctt cttcttgatt atctaatggc tgttgtaaaa
     1501 aaatgttctc ttcatgaatg attgtcatga taaacctcct gctcttcctt cttcgataac
     1561 tgtacgattt gttgctttat tatccctctt cttgtcttta tcagttactc ttttcttttg
     1621 gatcaaacct agtatcactc caccaacgat cgaaccaata agaatcgctg taacccattg
     1681 gatttttccc gtcactacag gtaacactaa aaaaccgcca tgtggggctg gtacttggac
     1741 accaaacaga taggtcaaga cagcagcaat tgatgagcct aacatcatcg ttggtaatac
     1801 tcggatcggg tctttcgcag caaacggaat agctccttcc gtaatatgag ttgatcctaa
     1861 aataaaatta accaaacctg cattacgatc attagtatca aaatatttac caaacaataa
     1921 agtagcaaaa ccagtaatca acggtggtgc aatgcaagct gctgacgcac cagccataaa
     1981 agtcgtgttt ccttgtgtca aaagagctgt tcctgttaca tatgccgcct tattaaccgg
     2041 tcctcccata tcaaacgcac acatacagcc aacaatcacg ccaagaacaa gtggattcga
     2101 atattcaaat ccagctaaaa agctcatcat tccttcattt atagccttca ttggacctgc
     2161 cagcaaagac atcacgatgc caataaatgc tacaccaata actggatata agacgattgc
     2221 cttcaagcca tctagttgtt taggtaaaat tatcagtagc ttttgcaaaa ataagataaa
     2281 ataacctgct aagaacccag ctaaaatacc tcctaaaaat ccagtaccgc cattcatggc
     2341 tacgattcca ccaacaaatc caacgactaa ccctggacgt ttcgcgatcc cttctgcaat
     2401 ataagctgct aaaactggaa ccatcattcc cattgctgca tcgtcaactg cttttaccat
     2461 tgccgctgta gcattgtatt gtgcatgatc tggatcagaa gaatagattc cccaaacggc
     2521 aaatgaaata gcaatcaata ctccgccagc taccacgaaa ggcaacatat gagagacacc
     2581 gttcatcaaa tttttataga tgctacgacc aaaattagca ccacttatcg cttctggttc
     2641 taaagtatca gcagcttcat tatctgctaa gacagtacct tttcctgcca atgcttcgtc
     2701 aatcagccgt tgtgcatcct tgattcctgt actgacagaa acatcaatga ctcgttttcc
     2761 cacaaatctt tctgaatgga catctttgtc tgcggcaata atgacagcat ctgcctgttt
     2821 gatttcttca gccgttaatt cattctcgat cccaatttgt ccatgggtct ccactttgat
     2881 cgtgatgcct tttttcctag ctgcttgctc taatgcctct tgcgccatgt aggtgtgcgc
     2941 aattcctgtc ggacaaccgg ttgctgcaat tagttgatat tttcccatct ttcgaacctc
     3001 tcttccttga ttttgatttg tttacttaat tcctccacat ccaaaaaatc agtcagtcct
     3061 ttacgaaaag cagtagagct gcctgctgct atgcttttac gtaacgtttc atcaagcgat
     3121 cgtcgattca tgtatcctgc taaaaaagtg cctaacatgg catcacctgc acatgctgta
     3181 ttgacaactt ttccttttgg cgagtttcct cgaatcaccc tgtctttcgt aaaaagaatc
     3241 gctcctttct caccgaggga taacaaaaca ttttctgcgc ctgactctac tagtcgttgt
     3301 ccataaacaa agtaatcttc atctgtaacc atttttcgtc cgaaccaaga agaaagttct
     3361 tcctcatttg gtttcagcaa aaacggtcga tagggtaaac aatccatgac ttcttgatca
     3421 ctactatcaa taatcaaaca aatccgactg atttctatta aaacctttgg agacagccct
     3481 cttggtaaac tcccagaaac acaaagataa tcccctgctt gtaatgctct tatttgattt
     3541 aaaaaattat gaacagctgt ctgcggtatt tcaggtcctt gattcactaa tttgtattct
     3601 tctcccgttt gattgacttg tgtaaataca ttgatacgcg tcataccagg cacttcaata
     3661 aactctgttt ggatttgttt ctgctgtaaa tagtcttcta tatactttcc tgtgaaccca
     3721 gcagaaaaac ctaatgccgt acttgggaaa tctagcatct ttaatactag tgacacattc
     3781 accccttttc cgtttgcctg aatgtcatcc tcttttgtgc ggtttaccat aaaaggatgc
     3841 atctcatctg tttcaataaa tagatcaatt gccaaattca tcgtgcatgt gtagatagac
     3901 ataaccaacg acctccttga ttctattatg aaatacgcga aatagaaaat gttttcttaa
     3961 tcgtcccaac acaaagaaaa cctttacatt tataaactcg tcgtgctttt tttaactaac
     4021 ttttggtgaa agaaggaaag aatatgaatc acaaattaag tgaaacagag cagtacctct
     4081 ggaactttat cgaacacctc atcctagaga tccctaacta ttccatcgtg aaactaagtg
     4141 aacaagcaaa tgtctcaaca gccaccattg tgcggacaat gaaaaagaaa ggctatgaag
     4201 ggtttacttc gtttaagcat catctaaaag aaggagaaaa caagaacatc aatttttcat
     4261 ttttagataa agtagacaaa ggaatccgcc gagccattct aaaaaatgaa caagaagtgg
     4321 tacgtacaat caatatgttg gaaatcggga acattgaaga tgcaatacaa agaatcaaat
     4381 ttgctgaccg ggtttttgtc tttgcccgag gattttcaga aatgattggc caagaaatgc
     4441 tggtaaaact tcaattaacg ggaaaaaatt gtcagatgca tactgatcca gaaattatca
     4501 aaagcatcag tcggaaacta actaagaaag acagcgttat ttttgtttct ttgaacggtg
     4561 agaaaacaaa taaaaacatc aaaaataaga tttatgtctt tatttttcaa ttttttaaat
//
LOCUS       DACBYO010000142         4620 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.142, whole genome shotgun sequence.
ACCESSION   DACBYO010000142 DACBYO010000000
VERSION     DACBYO010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.142"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(27..1259)
                     /locus_tag="IVD26_002784"
     CDS             complement(27..1259)
                     /locus_tag="IVD26_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP6080689.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1514..2083
                     /locus_tag="IVD26_002785"
     CDS             1514..2083
                     /locus_tag="IVD26_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6080690.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2261..2701)
                     /locus_tag="IVD26_002786"
     CDS             complement(2261..2701)
                     /locus_tag="IVD26_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAP6080691.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2859..3623
                     /gene="map"
                     /locus_tag="IVD26_002787"
     CDS             2859..3623
                     /gene="map"
                     /locus_tag="IVD26_002787"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAP6080692.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3655..4578
                     /locus_tag="IVD26_002788"
     CDS             3655..4578
                     /locus_tag="IVD26_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAP6080693.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
BASE COUNT         1396 a          857 c          912 g         1455 t
ORIGIN      
        1 ttttttgcat gtgtgcgaaa gtatactcaa gcccaatcgc catttcggaa aatcggtact
       61 gtagagccat cttcacggat tccgtcgata tccatcttgt cagatcctac catgaaatct
      121 acgtgggttt gacttctatt caatccagct tctgctaatt cttcatcgga catttctgta
      181 ccgcctttca cactgaaggc ataagcagaa cctagtgcta agtgattcga tgcgttttca
      241 tcaaataatg tattgaaaaa gatgatgcca gattgagaaa taggtgaagg gtcaggtaca
      301 agtgcgactt ctcctaaacg acgcgcacct tcatctgtat caagcagttt tgctaagaca
      361 tcttctcctt gttcggcaga aaaatcaaca acttttccat ctttaaaagt aaatttcata
      421 cccgagatga tggtgccagc ataactcagt ggctttgtac ttgaaatgta accatctact
      481 cgatgactgt caggtgctgt gaacacttct tccgtcggca tatttgccat gaatttttct
      541 ccacgagcat tatagcttcc agcgccttcc caaagatggt ttttaggcaa tccgataatg
      601 atatctgtac cgggagcagt atagtgaagg gcagaaaatt gttctcgatt caattcttct
      661 gctttttttg ctaatttttc atcatgcttc ttccatgcta agacagggtc ttcttcatag
      721 acacgagtcg ttttgaaaat ctgatcccat aatgcctcaa cttgtttttc ttctggcagt
      781 tctgggaaga cttttgctgc ccattgttta ccagccgcag ccacgacagt ccaactgact
      841 ttatttgctt gagttgcctt gcgtaaattc attagtgctt tgccattcgc tgattgataa
      901 gacgctactc gatggctatc tacaccagca aatgcatcgg gatcggcaga aacaacgctg
      961 atcctgcttg ctcctttttc aagccattca tccgcttgat cgattttaga ttgtggtaca
     1021 ttctcaatac gatccgttgc agcatgtaaa agaaattctc tttggatctg gtcgtcagtc
     1081 cattgaacga taacctcagc ggctcctagt ttataagctt cttgtgtgat caatcgagca
     1141 aggggtgcct gttccacgct gatctgtaaa acaactgtgt gtcctttttc tgtggctacg
     1201 ccagtttctg caattaagcg tgcatatttt tttagaagtt cattaaaatc agataacata
     1261 ataaaaattc ctcctcacca ttttttctgg taactattag catgatacca tttaattatg
     1321 attcaaacaa tgaggcttta aataaaaaaa ggaggttatt tttttaaggt taagtttcat
     1381 gatatatgtt actacttgct atttcagctt gtgaagaaaa tcaaaaacta attttgcata
     1441 tcaaaaaaaa catgttacaa tgaaattaat caatggtgga agcgttataa aaaaattaag
     1501 gagattaaaa aatatggcaa gaaaaaagac gattactaga gaacagattt tggcagctgc
     1561 ttatgaagta gctgccaccg atggatttac acgatttact gcgagaaaca tcgcgaacaa
     1621 aatgaattgt tccacgcaac cgatttatct tgagtttaaa aatatggatg acttgagaca
     1681 agctcttttt gagcagatct atgatcattt acaatatgaa gtgttcactg ttgagcatac
     1741 agggaatacg attatcgatc ttgcttttaa ttatatccat tttgcaagaa gagagaagaa
     1801 gttgtatcgt tcactgtact tagaagaata tggtggagga aaagagatgc agaatttctc
     1861 ttatacttac tttgtgaata cagtgaaacg cgatccagct tatgtgaatc tttcagaaga
     1921 gcagatcgaa tctttgtata atgggacatg gatcatagct actgggatcg cagctttgat
     1981 gtcttcaagc atcatccatc caactgatga acagattgaa aagatgatcc aagacagtat
     2041 agatgctatc ttgaaattca aagaaccaat cgaaatcgat tgaatatact caaaagttcc
     2101 acaaatcagt aggtaacaag agatgtgtca aaataaggaa aagttcgttt ttcttacagc
     2161 gtatgcattt ttaactcccg aagaactctt ccatgaatgc aatgaataaa agagccatac
     2221 agattgaata aatctggatg gctcttttat tgcaagtata ttaaattttt gcgactagtt
     2281 ctttagcgaa agcttctaaa ttttcgatat cttcttcttc agcattcaga tccactttaa
     2341 cattttcggc tccttttgat gcgcctgttt ttgcaaaagc agcatcgaaa tcatccaccg
     2401 atttgcagaa ttcatcgtaa aaagtatcac cagatccgca gacaccgtaa atttttccca
     2461 atagatccaa ttcttgcaag tcttcataaa agtctacgat ctcatcaggc agatcgccat
     2521 catcgtatgt ataagtagct actacgcaaa tatctgcctc ctcgaattca tctgcatcta
     2581 cttgggtaca ttcgttgatt tcgacttcga tatccagatt ttcaaatgct tctgcaacaa
     2641 tatcggcgat ttcttcagtg tttcctgtca tgctagcata tacgattttt gctaaagcca
     2701 tgatgtgcct cctcgtttat aattatttaa caattatgaa ttataccaaa acatcattga
     2761 aaagaaaata aaacctagag acacctgggg aatgtcattt ggctaaatgt atgccgctat
     2821 gttaaaatga gagggatttg taaaaaggag acgaaaatat gattacttta aaatcagcac
     2881 gtgaaattga aatgatggca gaatctggag ctttattagc agatgtacat aaaaatctgc
     2941 gtgattttat aaaaccagga atcacaagtt gggatattga ggtatttgtc agaaactata
     3001 tcgagagtca tggcggaatt gctgcgcaaa ttggctttga agggtatgaa tatgcgactt
     3061 gtatcagtat aaatgatgaa atttgtcatg gattccctcg taaaaagcct ttgaaaaacg
     3121 gtgatttggt aaaagtcgat atgtgtatcg atttgaaagg cggcatttct gattcttgtt
     3181 gggcctatgt agttggagaa tctacacctg agatcgaccg attgatggaa gtaacgaaga
     3241 aagctttgta catcggtatt gagcaagcac aagtagggaa tcggattggt gacatcggtc
     3301 atgctatcca aacttatgta gaaggcgaaa atctagcgat cgttcgtgat tttattggtc
     3361 atggcgttgg tcctacgatt catgaagaac cagcagttcc tcattacgga gaagctggaa
     3421 aagggttgcg gttgaaagaa ggcatggtta tcacgatcga acctatggtt aataccggaa
     3481 cttggaaaat gaaaatggat cctaacggct ggactgcgta tacaagagac ggcggacttt
     3541 cttgccaata tgaacataca ttggctatta ctaaagatgg tccaagaatt ttgacatcac
     3601 aaggagaaga aggcacttat tgatctatcc agtcaatagg tacgggagag gtacatgaaa
     3661 gtttggaaca aaataaaaca aaatgaaaat ctgatgcgct ttattgagac gactcaaaag
     3721 cgcatcactg attcagaaat gagtacgacc tctgtcgtcg ttgcttatta tttactcttg
     3781 tctttatttc cattgattat tgcttttggt aatattttac cgtttctcca catcgatcaa
     3841 gagactgtac tgacctattt acgagaagtg attcctgaga ccgtttacca gtttatcggt
     3901 cctgcaatca aagacctttt gacacaaagt tcaggaggct tgttatccgt ttctgcatta
     3961 gcggctttat ggtctgcaag tcaaagtatc aatgctttgc aaattgcgat gaataaagcg
     4021 tatggcgtag aaaatagaaa aaattttttg atcgtccgtt tcttctcact aattgtcatt
     4081 gtcttgttca tgattgctat tagtggggta actatcgttc ttgggttggg acagctgatt
     4141 ttggatgcta ttcagccaat cgtacaaata cccgtgaact ttatcgatca gttccaaact
     4201 ttgaagtggc caatcacatt ggtagcttta tttgtcatca tgttcttgat ttatttaatt
     4261 gtccctaatg ctcagttgaa gttgaagacg atcattccgg gcacgatctt cgctactgtc
     4321 ggctggatgc tgttatcaca agtgtttagt atctatgcta ggtattttgc aacgaggatc
     4381 agcggttatc agatcatagg aagttttatt gtactcatgc tttggcttaa ttttgctgct
     4441 acgatcatca ttttgggcgg aatcatcaat gcagttgttc aagaatacgt gacgggtcat
     4501 caaatcaaaa aacgtcgaga tccaagccga aaatggttca ataaattgaa aactaaattt
     4561 tctcataaaa aaaagtagaa acaagagttc ttattgtaaa tttatatcag taatttattt
//
LOCUS       DACBYO010000143         4594 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.143, whole genome shotgun sequence.
ACCESSION   DACBYO010000143 DACBYO010000000
VERSION     DACBYO010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.143"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            190..2859
                     /locus_tag="IVD26_002789"
     CDS             190..2859
                     /locus_tag="IVD26_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAP6080694.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2950..3570)
                     /locus_tag="IVD26_002790"
     CDS             complement(2950..3570)
                     /locus_tag="IVD26_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6080695.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3684..4223
                     /locus_tag="IVD26_002791"
     CDS             3684..4223
                     /locus_tag="IVD26_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080696.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4220..4558
                     /locus_tag="IVD26_002792"
     CDS             4220..4558
                     /locus_tag="IVD26_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HAP6080697.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1424 a          790 c          860 g         1520 t
ORIGIN      
        1 aaaaattttt aagggtggga cttttgattc ctaccctttt tttgcgttta tttttgttat
       61 acgaacaaat tatgaagtta tttattctaa attttatttt tttgtgaaaa ttagactctt
      121 tttaagcaga gaaaaacaag gatatgataa actgaataca acttcataga aatttggtgg
      181 aaaataaata tgaaaaaaaa tttaaagtca ttctttagag aaaacggacg ctacgcagca
      241 gctagtttcc tgattccgtt tttgatttta gcacttgttt atctaagtat cgggatctat
      301 cctggaagca gcagaagtat tttggcaagt gatgcctttt cacagttttc taattttcat
      361 gccagcttcc gaaatgttct tcttggaaag caaagtattt tttatacatg gaatgcttct
      421 ctaggattga attatttatc tttaatttct tactatctag gcgggatctt cacgccactg
      481 gtgttctttt ttccaaacca gatgatgcca gatgcactgt atgttctgac tttgcttaag
      541 gtcggctgtg ccggattggc tttttggttt cttgcacgta cgttcaagat tcctcgctgg
      601 gggcatgttg cacttagcgt cagttacgca ttgatctcat ttatcactgc acattcggag
      661 atcatcatgt ggctggatgc atttgtttat cttccattag tgattttggg gattcatcgt
      721 gttatggatc ttaaacggcc gaaactttta tttatcagtt atttactctt gtttttatcc
      781 agtttttata tgggttttat gattggcgta ttttctttct tatattttat cgcccgtcta
      841 ttgacaaact ggtcagaata taaaaaaacg attgttcctt atggtatcac ttctttactg
      901 gcaggcggcg cttcaatgat cattgtattg ccagcagtgc tggatcttcg gtcaaatggc
      961 gaggcactga gtcagatcac tacgttgaaa acagaagcga cttcttatct ggatctaatc
     1021 atgaaaaata tgattggtgt ttatgacacg acaaaatacg gatcgattcc gttcgtttac
     1081 gcaggtctgc taccattagt cctctgtctg ttttattttg ccagtcggaa agtaccgttg
     1141 aaaaataaat ttttgtacgg cagtcttttc gccatactta tcgcaagttt ctatcttgtt
     1201 ccattgaatt tgttctggca tggtatgcat gcaccgaata tgtttttatt ccgttatgcc
     1261 tatctgttct ctttcttagt gctcctgctt gcaggaaaag gatgggaaaa gatagaacaa
     1321 gacgatcgtg ggctgttgtt aggaatcatt ttggtcgtag ctgctctctt tgcggtggca
     1381 tggggcatca aacctgaagg aagctacacc tatgtgacga tgacttcctt tgtattgaca
     1441 gtggttttct tagggattta tgcttttgct gtgggatttt atcagcataa aaaactttca
     1501 ttcaatcatc tgagtatatt gttattattg atcatgtctg ctgaagcact ggtcaatacg
     1561 aacagtatga tccatggcat tcttgatgat tggaattatg cttcccgcag tttatatact
     1621 gatccttatc ctgacttgaa agctcttgta aatgaaacaa aaaaagattc cgactcgttt
     1681 taccgcttgg aaaatctgga tccagtatct gcaaacgatt cgatcaacta tggttacagt
     1741 ggtatcagtt tgttttcttc tataagaaat cgtaattctt cctcttacct ggataaatta
     1801 ggtttccgtt caagagggac aaatttgaat atccgttata acaataatac tttgctaatg
     1861 gatgggttta caggaatcaa atataacatt tctaaaaacg aaagcacgtt cagtaaatat
     1921 ggcttccgcc aagctggtca aagtggcgac tatacactgt atcagaatgt caatgcattg
     1981 ccactagcat ttactgcacc gttgtccgtt aatgatgttg agcagccagt gacagataat
     2041 ttgaccagtc agacaaactt gatcaataca ttgtctggtt taaatgaaca gtattttaca
     2101 ttctatacac ctactttgaa gaatcagttg aatacgacga tcacaaagac aacgactggc
     2161 gtcacttact cagaaacagc agataaccag ccaaaagagc tcacttggga agtccatgtg
     2221 cctgcaaata cacaagctta cttaagtttg ttcccaacca attttgcaca attagaaagt
     2281 tctagtgcga cgatcactgt caatggtaca tcgcgaaaaa cgcaaatcaa catttctggt
     2341 caatactatg atcttggcta ttatcctcaa gagacaacag tgacatttac tgcaagtttt
     2401 tatggaacga aagaagtaag tttcatggag cctaaagtcg ttggtctaga tgttgtagcc
     2461 tatcaagccg caatgaatca gatcaaagaa aaaggtgtcg aaatggaagc cactggcaga
     2521 aaagcttctg ggactgtaaa taccgctgaa gattccatgt tggtgacaac tattccttat
     2581 gacaaaggat ggaaagctaa aattgatggg aaaccagtca aggtcagcaa tttcaaagac
     2641 gcattcttga tgataaaagt tccagcaggt aaacatactg tcactttcag ttacttgcct
     2701 gaaggattta cgataggtgc aatccttttt gtcctatgta ttgcattgtt tattctttat
     2761 gtctggtacc ttgaccgcaa tcgccccttt tatggcacga ttgatccagc aatagaagaa
     2821 aaaccgcgaa atacacacag aagaagacga agaaaataaa gaaacgatgg aatctgtgtc
     2881 actcttctat ttaaatggca aaaatttcaa tctttaaatg acaaaaacca cctgattttt
     2941 ggtggttttt tatataccta tgactaaact atctcttgct gcttcgacaa cttctacagt
     3001 gatcttatcc atttgattga ttcttaaaat ccgatcaatc tgcgcaaata aacgatgaat
     3061 aagcctaaaa tttccttttg tgatcttaat gatagttgtg atagcctcat aatcagaaaa
     3121 atcttctagc ttgatatcaa ttcctaaatc tgcccatttg tattccaaaa tatgatgtgt
     3181 ttcgtcctta ctaaggttat caaattcatg tgcaaatcct atgcgagagt aaagctgcgg
     3241 ataacgagac aatctttttt caataccagg cataccgata agaaccattg ccagatcatt
     3301 tctatcgtaa atatctctta gctgttctaa atgctgaagc tttaaacgat caatttcatc
     3361 gacaataatt aagtcaattg cttcataggt tttaggcaca ggaggatctt cttgattgta
     3421 ttttagtacc atatgcattg ctttagtcag acctattcta ctagttattg tgttaatatc
     3481 cgaactgaca cgagacatct tttcagctgg tacagtataa aaaactttat ttacacttaa
     3541 tatttcatct gttgcattta tcaagaacaa gaaaaagtct gaatattcaa aaaaaataac
     3601 ggtgtacatt tttaaaagga gatgtataat cgagatttag aaagcgtttt cctcaaaatt
     3661 taatgaatta ggaagtgatt actatgaaaa aattatttag cgcacttttt attctgttat
     3721 ttggctttat tggtattggg acttctggaa atatagttaa agctagcacg atggttgaac
     3781 aaacaagtga aatggcaaaa acttttagtc aattaacacc agaagaacaa agttacttca
     3841 aatccaaagg atttagtgat aaagatactt tttacactca aaagatagag cctcaagatc
     3901 cgaaaacacg tttttctgca aatgtattgc ggttaaccgc atctactaaa aaaattacta
     3961 atacgcaggg gcggacagaa tatattataa caagtcccaa ttcggcgatg tatcgtattt
     4021 ctacacgctt gagtttaggt agtgcaaaat catatactca aacagtaaat ctagctaatt
     4081 cttatggtta tggtggagga atgtatttta catttactgg gaaaagacaa tattacagtg
     4141 taaaattagc tatgcaagtt tataatacat ttggtgtagg gtcagtctct tgcactgcgg
     4201 gaggattgac aataggaaaa tgataatttc ttactatgtc ttaaatagaa gtgatgatga
     4261 aggactcttc gtttttcaat cattacatga ggatacgatg ctaaaagagt tttataatcg
     4321 gattaagaat aaacagatag aaacaaattt atatttttta agtgactcta tcttgccttt
     4381 tattagcaac cctaaaattc ttaacttgtt gcagacaaaa gatttgaaaa gtttaccgat
     4441 tattgtcatt gatgaggaaa ttgtaaaata tggcgcttat ctaagcgtag aagaattaga
     4501 aaaattaact aacattggaa tgagtattca ggaggataat ggggtacatg gaacatagaa
     4561 tgaatatgca cagttgagaa cggaatttga catt
//
LOCUS       DACBYO010000144         4506 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.144, whole genome shotgun sequence.
ACCESSION   DACBYO010000144 DACBYO010000000
VERSION     DACBYO010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.144"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..547
                     /locus_tag="IVD26_002793"
     CDS             <1..547
                     /locus_tag="IVD26_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080698.1"
                     /translation="KIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYGI
                     DETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTLL
                     ISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLSE
                     EKILLPENWAELRKLVEYGII"
     gene            534..1955
                     /locus_tag="IVD26_002794"
     CDS             534..1955
                     /locus_tag="IVD26_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAP6080699.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            1968..2975
                     /locus_tag="IVD26_002795"
     CDS             1968..2975
                     /locus_tag="IVD26_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP6080700.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            2987..3991
                     /gene="neuB"
                     /locus_tag="IVD26_002796"
     CDS             2987..3991
                     /gene="neuB"
                     /locus_tag="IVD26_002796"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAP6080701.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            3988..>4506
                     /locus_tag="IVD26_002797"
     CDS             3988..>4506
                     /locus_tag="IVD26_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAP6080702.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGA"
BASE COUNT         1584 a          576 c          811 g         1535 t
ORIGIN      
        1 aaaaattccc aaaatagatg aaaacagtaa attgatgaaa aacatacaat caatctttgg
       61 gatagaagaa gtttttgtcg gagataaatg tatctttttt gatcaacctt tattatctga
      121 tggttatggc atagatgaaa cagatatttt cgctaaagta aatagtatat tttctggaaa
      181 aaaagaaact ttaattaagc ttcatcctag agcaaggaca aatcgttatg gtgaaaaaaa
      241 catattgaat tccagtttac cgtttgaagt cttgctactt gaaaatgact tctcttcaac
      301 acttttgatt agtcctatat ctacaatttc tttttcacca tctatgatgt ttgaaaagac
      361 gatcaactct attatgttgg ctaaattaat tttaaatgaa tatacagcat tatctgaaga
      421 taaaaaagaa acattgacaa atattgttct tttctgtgaa cattataacc gtctatcaga
      481 agaaaaaatt ttactcccag aaaactgggc agaattaaga aagttggtag agtatgggat
      541 tatttaacac actttccaag tcaaaattag ttaagtccag tttctggtat actataggga
      601 atttttttat taagggaatt tcattcataa ctattcctat ttttgtaaat attactactc
      661 aagcagaata tggtttgatt aataatttca cttcatttgt atcaattttt tcgattcttg
      721 ttgggctaag cctaaattcg gcaattaata atgcaagttt tgactataaa gatgacataa
      781 atgaatttat gtcatcggta ctttctctag ctacactttc gttaattgtg ttcttattaa
      841 tagggaacat atattttttg ttttcaaatg ctttttttga tatgaaccaa cttgtattta
      901 atttgatgtt attacaaagt tttgctagtt ttgtaattag ttatatccag tcttatttta
      961 cgattaactt taaccatttt aaatatttga ttttatcttt tatatctact tttttgaata
     1021 ttgcaatctc tgtagctttg atgcagacat tatattttga tgataaatat gttggcagag
     1081 tagtcggcgg aacactgtca tttgtgttga taggtttagt aatttattta agaataatga
     1141 taaagggtgc tcattttttt gataaaaaac agtggagata cgctttaaaa atctctttgc
     1201 cgctaatccc acattcctta gcaaatatag ttttagcaca attcgataga attatgatta
     1261 attcttattt aggtcctgct gcggggggaa tatattccta cattagtaac ataggtatta
     1321 ttctaagcgt aatatggatg tctactaata acgcctgggt tccatggttc tatggtgaga
     1381 tgagtaaaaa taatgaaaaa aaagtgaaga aagttagtaa ctattattta gtagtcttta
     1441 ctttgattac gatgattgta atggtagttt cgattgattt agcaaaattt atggctccga
     1501 aagactatta ttctgggtta tctttagtgg ttccgataac cttaggctat ttctttcagt
     1561 ttttatatag tttaccagtt aatgctgaat tttatgagaa aaaaacatcg tttattgcga
     1621 ttggtacagt agcaagtgct atagttaata tactattaaa catgattttc atacctaggt
     1681 taggaataat tgctgctgga tacacaaccg tatttacgta ttttttactt tttatttttc
     1741 attataatat cgctaaaaaa attacgaata aacaattatt tgacacaaaa aaaatatgta
     1801 tcataataat ttttgtatca attttttctt tgatacttca tattttaatc aatcaaatgt
     1861 tgattcgtta cgttttgaca tcattattga taattagttt agttatatat tttttaaaga
     1921 ttaagaatcg aattatagat gactataatt cataggagga gatataagtg tttaaaggaa
     1981 aaacaatatt agtaactggc ggaactggtt ccattggaag tgaaattgtt cgtcagcttt
     2041 taaaatatga accaaaagct atcagaattt atagtagagg tgaagaaaaa caattttata
     2101 tgcaacaaga gctctcaaat cacactaatt tgagattttt aattggtgat atcagagact
     2161 ctcaaaggat tgattatgca tgtcgtgatg tggatattat ttttcatgct gccgcaatga
     2221 aacacgttcc agcaagtgaa tataatccta tggaagctgt aaaaacaaat gtgatgggaa
     2281 ctcaaaatgt aatagatgca gcgatcaaaa ataatgtaaa acattttgta ggtatcagta
     2341 cagataaagt agtgagtcct actaacacca tgggtgcgac aaagttattg agtgaaaaat
     2401 taataatagc tgccaatcag tataaaggaa aaacagaaac aatattttct tgtgtaaggt
     2461 ttggaaatgt catggggtca agtggatctg ttattcctct ttttagtaaa caaataaaaa
     2521 acaataaaga tattactttg acagatgttg atatgacacg atttatgatg tcaataccgg
     2581 atgctgcaag attagttctg tctgctgcta tgaattcaaa atttggagaa acatatgtct
     2641 taaaaatgcc ggcaatcaat attttaactt tagctcaatc attaataaaa atatataatg
     2701 atacacatga tgaaaaatat agaggtgaaa taaaagttgt aggtatcagg ccaggagaaa
     2761 aattatatga agagctaatg actacagacg aaattgaacg ctcatatgaa aatgataaaa
     2821 tgtatatcat tccaccacac tatcatgcta ctgacgaact gtacaaagat tatgaaaaaa
     2881 ttaaaatcac tgcatactct tcagatgcaa cagaattaat gagtggacag gaatttatta
     2941 gaatcgcaaa agagaataat gtcgtgactt ggtaaggagt tttatgatga aatcagaagt
     3001 atatgtaatt gcagaaattg gtgtaaacca taatggaagt ctagatttag ctttagaaag
     3061 tattgataaa gctaaagaat gtggagctaa cgcggttaaa tttcaaacat ttaaaacgaa
     3121 taagctagtt tccaaaaagg ctccaatggc aaaatatcag aaggataatc ttaaagagga
     3181 cagttctcaa tttgaaatgc taaaaaaatt agaattatct caatctgatt ttattagaat
     3241 aaaagattat tgtatacaaa ataaaattga ttttttgtct actccttttg atgaagaaag
     3301 tgcagacttt ctaaaacaaa ttggtgtaca aggatttaaa attggctcag gagatttaac
     3361 aaatttacct tttcttagaa aaatagatat gtatgggttg ccagttttat tatctacagg
     3421 tatggctgat attcatgagg tcagtgaggc tgtagattgt ttcatagata gtccagttac
     3481 tattttacat tgtacttcaa attatccggc tagttctgaa gatattaatt tattggcgat
     3541 taacacatta aaagaaatgt tcgggatacc cgttgggtac tccgatcatt cattgggata
     3601 tgatgttggt atttgtgctg ttgcgatggg tgctaaggta attgagaaac attttacctt
     3661 ggataaggaa ctacctggtc cagatcataa agcttcttta gatcctcagg aatttgcaga
     3721 ttttgtaaag catattagaa acactgaaat atttttaggt gatggtgtta agcgagcaat
     3781 gccttctgaa cttagtacaa aagaagtatc aagaaaaagc ctagtggtca ctgagaattt
     3841 aaatgtggga gatattctta cagagaaatc tcttacaata aaacgtcctg gaaatggaat
     3901 agctcctaag tttttatatc aatatattgg caaaaaagtt aaaagaccaa taagtgcaga
     3961 tagtgttctg cttgaggaag atgttgaatg aaaaaaatac ttatagtaag tggaacacga
     4021 gctgattatg gaatatataa acctgttgct gagaatttac tacaagataa ttgggatgta
     4081 tcatttgttg tttctggaat gcatttatcc cataaatatg gatttactaa agaattgatc
     4141 ttagctgacg gatttagaat tagtggagaa gttcaaagtt tgtttttaga gaacaataag
     4201 ggaaacatgg ctcggtctgt ggcattagag ataaatggtt tcacaaatat atttgaacaa
     4261 actagccctg attttgtatt attactaggg gatagaggag aaatgttggc agctgcgata
     4321 gcttgtttgt atcttggaat caaaacagca catattcacg gaggcgaagt gtctggtact
     4381 gtagatgaat caataagaca tgccataacg aaaatagcat ctgttcattt tgctgctacg
     4441 gaaaaaagca aagagcgttt aataaaaatg ggggaagatt cttggagagt ttttcccgtc
     4501 ggagct
//
LOCUS       DACBYO010000145         4461 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.145, whole genome shotgun sequence.
ACCESSION   DACBYO010000145 DACBYO010000000
VERSION     DACBYO010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.145"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            574..1008
                     /locus_tag="IVD26_002798"
     CDS             574..1008
                     /locus_tag="IVD26_002798"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080703.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2298..3221
                     /locus_tag="IVD26_002799"
     CDS             2298..3221
                     /locus_tag="IVD26_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP6080704.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3237..3776
                     /locus_tag="IVD26_002800"
     CDS             3237..3776
                     /locus_tag="IVD26_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP6080705.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1665 a          667 c          759 g         1370 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacagagaa cttaaattga attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagaaacg gataaataat aaaaaagact
      181 gctcttccga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcaacgcgct
      241 tataaagcgc taccaaaaat ttatcatatt ttatgaaaaa taacaatcca gtaaaaaatg
      301 actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa gccttaaaaa
      361 gagcttttga cctagaccaa ttaaaaatca caaagtgagc ccctgtatcg gttgatacaa
      421 gggctacttg gcatagtaca cattatgtct actaaccttt aaaataacac gttttataaa
      481 ataaaccctc ttgacaatat ttaattttct gattattcta aatatataca gaaagcgctt
      541 tcctaggatt ttatatctaa ggaggaagta acaatgaaaa ataaaattat taaaattatt
      601 acttgtctat ttttgttcgg tatgattgtt ggagcaagta ctccgttaaa tctgtttcct
      661 tttagtgcta gaggtataaa agtggaagct gcaagttcac gatataatca taatcatcgt
      721 ggatttactt gctataaaat gaactattat gttactaata aaatgtgtag agatttgaaa
      781 aaaaattata ataagctaaa gactcctgct caaattgcat cttttattcc tattggtgga
      841 gttggaacat gggttattac aaatgctttt agtagtgctg ttgatgcaat gaatgtcttt
      901 gtaagagctg caaatcaagg aaaaggtgta caattaacat ataatgctca ctttagcaat
      961 acaacatcat atcaatacaa tgattacgct cgttatgtaa taaaataatc agaaagtgaa
     1021 actatctcat gaataaaaag attttagctg taattatttc aataatagtt ttaatcacta
     1081 tgttcttcat atttaggcta attttcaata taagcttaca aaaaagtatt ctttatctaa
     1141 ttcctatagc atttatctta gcaattttta gaagtattta cggaaataaa aactctaaat
     1201 agctaaaaat aaatcatact aaattttaca aaaagtggct agcattttct agccactttt
     1261 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
     1321 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaaccc
     1381 ttttagtgag ttttgtagaa agtaccttta aaggtacttt cacattacga acgatacgtc
     1441 cgtaggacgt actgaaaggg tgggacttat gagcaaatta atgcaaaatt tggctagcaa
     1501 aaaagctaaa aaatatatgc taataatcga gcgaaataaa cactttttca agtgagcgaa
     1561 tccgccatga caaagctgaa gcagtttatt tcagctttgt catggcgtgt gccgactttt
     1621 ttaaaagtct aggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
     1681 tttgaaacgc ctaagtatat aaatatataa gaataggttt aagagtgctt aaatcgaatt
     1741 ttagagggca tttagacaat tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     1801 ttttaagaac aagataaggg atttatacta ggactgtctt aaaatgtctt aaacgaacgc
     1861 tcagagcttc tcaaagggtt ccttatgaac ggcttttagc aaaggagccg gaggcgactg
     1921 cgcagtataa tgtgagagca gagcgatcac acctttttag cgaaccgtag ggagcaaggt
     1981 ttggaattgg cagttttgat aaattcgcga acctgtttag agaaaaaagg agtgattttt
     2041 taggcgggaa aattagcctc ccctcttttt atatctcttt ttatatctct ttttatatct
     2101 cttttatgtc ggctgtgtcc ttactctccc aagcaattca gagttttttc aagtaggttt
     2161 tctacgcttt tcaagtaggt tttctacgct tttcaagtag gttttctacg cttttcaagt
     2221 aggttttccg acattattga gtatttttat aaagtatgtt acttttattt catactttat
     2281 aaaagtagga gaagcttatg gcaaatgaaa ttgtaaaata tgaaaataga ttaaatcata
     2341 ttcctctgag aaaatttaat agtcgtgaaa tgaacttatt tttttcaatt gcttcacgtg
     2401 tacgtgaaaa aggtgtagat gagattattt tttcatttca cgatttgaaa aaactaagcg
     2461 gttatacaga acgtggggaa caatttataa aagatcttag tagcacgtat gacaaattat
     2521 taagtattaa tgcttggaat gatgatggaa atactttaac taaatttgtt gctttcacaa
     2581 aatatagcat tatacgagat aaacaacttg ttataatttc agttaatcca gaatttaaag
     2641 gactttttaa tcaattaaag aactggacaa gatttaatct agagcaattt actaatttgg
     2701 atagcacata ttcaaaaact atgtttcgat tattaaaaca atatcgaact caaggctgga
     2761 ctgaattttc caaagaaaaa ttttttgatt tactagatat tcctaaaagt tattggaata
     2821 gtccgtcaaa tattgacaaa tttatcttaa ggccaattaa agaagaactc actcccttat
     2881 ttaaaggatt aactattcgt aaaaaatatg gtaaaggtcg aggtaaacct gttatcggtt
     2941 atcgttttac ttggaaagct gaaattaacc atgctgacga tttttccaaa gggaaacaag
     3001 aagatttacg tataaaatta tttaatattg atcacaatgg agaattaaca cgagaagaaa
     3061 aatggcgcgc taaagatcga atactaaatc ttcccttagg cactcatgaa gctgatttta
     3121 aacaacaaca acaaactgaa gaaaaacagg cagaaaaacg agaactttca aacaaactca
     3181 aacaagattt actaggaaat ttacaaaact tattcgatta agcttaagga gtatttatgg
     3241 cagataaaac aatcaaagaa cttgcggaag aattaggagt tagtaaaaca gcaattaaca
     3301 aaaaagtttc tgacaaaaat cgaaaacttt ggtttgcaaa aaacggaaac aagtttgtga
     3361 ttaacgaaac cggtcaaaaa gctataaaat caatgttttt agtcgataac gcaaacttaa
     3421 atcgaaaact agttggcgaa aaatcaaaaa ccaaaaacca taaaaacacc aaccaagttt
     3481 ccgaattaaa actcctttct ttcctagaaa aacagttaaa tcgaaaagat atacagctac
     3541 aagaaaaaga taatcaaata aaacaaatgc aaaaattact cgaccagcaa caacaactca
     3601 ctctacaagc gaaccaacaa attgagaacc tacaagaaca gctccattta acttatacag
     3661 aagaaactcc aacaaccgaa tcaactgcct tttctgaaaa aaaagcagac aatacacaac
     3721 cacttattga aaaaaagtgg tggcaaattt ggaaatctaa tagaaccaat ctctaaaatt
     3781 ttctagaagt tagttcggat agtagaggaa aaagttgtac tacctgatgg ggagatcact
     3841 caaattttta tgagaaagaa aaaatagttt acaactgtaa acaatcaatg tttatagttg
     3901 taaactatca aactatatgg tgacttattg cttaaaatag gttgaaatct cactcaattt
     3961 ttggtggaaa aacaaaataa attctaatcg attttgttga aaaagtcata aaaaaacaaa
     4021 tgtgatttta acaaaatttc aaaaaaatcg tttgaaattt cgtttatttt ttttgagaat
     4081 tttgatcatc gtagggtcat tgtagaatca ttatgagatc atcgtgggat catcgaataa
     4141 agtatgggaa aggcttgcgg tgcttggtat taagggcatt ctccgcctcc caggttcttg
     4201 accattttct cttataagtg ggatttttac cacgttgaga gaaaatggtc aagaacctgg
     4261 gaggcggaga aaacatacca agcaccacaa gcaaaaaaag ttagagtaac ttccaaaaaa
     4321 gaaaaatttt ttagaacaac ttttgaaaat ttaattttga tttatatccg ttcaatttaa
     4381 acatttgata aactgaaggc tagtatttaa aatgtgtata caagtggtag cgttaaaaaa
     4441 agtggaggta taacctatgt t
//
LOCUS       DACBYO010000146         4458 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.146, whole genome shotgun sequence.
ACCESSION   DACBYO010000146 DACBYO010000000
VERSION     DACBYO010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.146"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            417..1136
                     /locus_tag="IVD26_002801"
     CDS             417..1136
                     /locus_tag="IVD26_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP6080706.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(1217..1900)
                     /locus_tag="IVD26_002802"
     CDS             complement(1217..1900)
                     /locus_tag="IVD26_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAP6080707.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            2119..4305
                     /locus_tag="IVD26_002803"
     CDS             2119..4305
                     /locus_tag="IVD26_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP6080708.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         1662 a          739 c          882 g         1175 t
ORIGIN      
        1 agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca atgataccgc tcataatctg
       61 cactggcagt tagttgtacg caaatcaagt acaatagaag aataaaaaca gataaaatgt
      121 tgagagcata aagaggttgt gagtctcccg tttagctctg agttacaagg aataatgtta
      181 aaaaacagct tttcatgttt tatgaatatt gccttgtgac cgaggtgttg gcaggagaat
      241 actgtttatt tgaaaaaagg gctgcgacaa gacttttgtc acagccttta ttttcatgaa
      301 taggagttac ttttggctac ttttagagaa gtagctttta aggagcagat aaagtcaagg
      361 cttttatttc tataaatgaa gtagtaaaat gaagaacaga ttttattaca ggaaggatgc
      421 cgataattgt gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca ctaactgaaa
      481 tgcttgccca agatttagaa acaaaacctt tttatgagaa cgtggaagat aatgaagtat
      541 tgccgctatt ttattctaat ccagaaaagt atactttttt attacagatt ttctttttga
      601 acaaacgctt tttggcaatc aaagatgctt tcagccatga tgacaacgta ctagaccgct
      661 ccatctacga agatagtatg ctgtttcatt tgaatgcaga tttagggcgt gtttctgaag
      721 tagaagtaaa gcagtatgaa ggtcttttag aaacgatgct gaaggagtta gaagaaattt
      781 cgccacaaaa gaaaccagat ctactggttt atattcgtgt atcctttgaa actatgttag
      841 cgagaatcaa aaaaagaggc cgggaatatg aacagctaga acaagatcct gaactctatt
      901 cctactataa agaactcaat cgacgatacg aagagtggta tgaacagttt gatatatgtc
      961 ccaaaatagt gatcgatggg gacaaatatg atttcgtagc cgatccggca tgtggagaac
     1021 aaatcgtaca agaaatcaag atgcgggcaa agaaaatgac agaagaggca gatgcccagt
     1081 cgatccgcta cactacaaat aacccgaaag caaagggaat ctttacaact aaataatata
     1141 aaaactaagc aaattgctca ctcgcagata tttctctgtg agcagcatct tgcttagttt
     1201 ttttgattca ttgagatcaa atagtgaacc gattcgtatg ataaaattgc cataaatgaa
     1261 atgtctgagt gagggccatg atcaaaaata aaatggaaac gatcaaaatc gaatgggcgc
     1321 caaacagatg atgacagaaa acaaggacaa tagctcctgc gataaaggca agaacgacac
     1381 ttagatagtg gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa taatcatata
     1441 agttcgttgc tacccctttt aaatttccag ttgtaaataa attagtgtag gcacgcccgt
     1501 tgattttatc aaaagctacc cactggatcg atgcagtaaa agcaatcaaa atcgttacta
     1561 atgcgggatg ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact gcttcataat
     1621 atagaacaaa caagcgccag aaatgttttt ctttttttct aaaataatca attagatact
     1681 ttgttagaag aatccctaag aaaaagaaaa gggtagacaa tactttttta ccaacactta
     1741 gccattctcc gtcaaatgct tggatgatcg atagaatgat attgccagtt tgagcagagg
     1801 caaaagcacc atattggata taagtataac tgtccatggc tcctccgata aatgtcagca
     1861 aaagtcctat tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc accttttatg
     1921 aatatttttg tcttccttat cttagcataa acgattgaaa aaaaaggaaa aattttcaga
     1981 aaactaaaat catatcgctt cccattttca tttttagaaa ggtctgttag tataaagaaa
     2041 aaatagacaa cgaaacttta aataaccaac ttgaaataaa caaattcaaa gaagaaagat
     2101 gggaaggaaa tcaatcagtt gaatgaaaaa gaaattctcc gattacaaaa agaattgaaa
     2161 cgctgggaga acaagtataa aaagcttcaa caagtctttc ggctacaaga agaaatcatt
     2221 gctacctatg aagcggctta tggcgaagca cccggactta ttgaggaaga agtacaagta
     2281 aaagaaagtg aaggaaacag ctctttcttt aaaatgatgg agaaacgttc ctataatcgc
     2341 ttcaatcaag aacaaaaagc agctatcaca tatgatatga agaaacatct tcgaatcata
     2401 gcaggagctg ggagcggcaa aacgcaaaca atctgtgcaa aagctgttta tctgatgacg
     2461 caaaaacaag tagacgaaga acgcatacta atgatcactt ttacaaggaa cgctgcaaat
     2521 gaactaaaaa aacgagtaga taatttcagc cagagaaaaa ccgctgtcca tatcggaaca
     2581 ttccatagta tcttttttag gatatacaat gaaatttgtc gaaaatttcc tgaagtagca
     2641 atgcaaggaa tacaaggaga cttttcaaag gatactgcac aaaaagtgaa tgctgttttg
     2701 caacagctga tacgtaaata taatctttat atatttgatc aatatggaga aaaaacgatt
     2761 gcttctcggt tagactattg gcagaatatg aacctttcag tagaagaaat ggttcagtta
     2821 gttaaagaaa aatatgattc cattgataag aatgcacgac agccgatatc agaacgactg
     2881 tatggattgc tcacggaact ccaagaacaa aaaagaagcc agcaattgct agagttcaat
     2941 gatgtactcc aaaatctgaa aagcgctttg gagaatgagg agatccagca ttatatcggc
     3001 caaaaatatg attatctatt cattgatgaa tttcaagata ctaatccact tcaatgggaa
     3061 atcgtgaaac ggatgacaaa ggaaaacagg atcaagttga ttgttgttgg agatgatgat
     3121 cagagtatct atggattcag aggatcagag ccagcataca tcaagaactt tgaaaaagaa
     3181 tatcctacca aaactctttt cttattaact aattatcgtt ctcgggcagc tattgtccaa
     3241 ggagcaaata gattgatcag ctataataaa aatgatcgga taccaaaggc gatgattcca
     3301 gcacaaaaag aagcaggtgt tatggaagcc tatttgtttt ctgatactaa agcagaaagt
     3361 cagtggctaa tcaaacaaat tcagacattt attcaaaaaa atgggaaata taaggaatca
     3421 atcatattat accgatcagc ttcacaaacg cagcagcttg tccaatctct gctgaaaacg
     3481 aatattcctt ttgtactgga agcagatagt ccatatgaag gtatctttgg tatcaagtct
     3541 ttccaacatt tctatcaaaa aattgttcat tggcaaacag cactgaatct gcaaaagaaa
     3601 aatcaggcct accagcaatt gctccggcag ctgatggcag actgctacct gaaaaaaagt
     3661 gaatgcgatc aatacttttc tcctaaatat caaaatatag ccgttgcaga ttatattttg
     3721 tcgataagcc ccaatttaaa atcgaaatct gcagaaatcc gagagtttga ggaagcgttg
     3781 cgtaaaacag accagcatca agaaatctat tcgcttgttc aaagctatct tcatctgcca
     3841 cgtatagcta aggaaatcga ccagagtgat caagaatgga tacgagaaga agtaaagcag
     3901 catgctactt tcagaagact ccaagcctta tcgcaagaaa cccaagcgac agctaaagaa
     3961 ttaaaaaccc gcttgattgc ttacagacaa ggaaaacttg atgcactatg tatccagagc
     4021 attcacaaaa gtaaaggtct tagttaccga aatgtctttt tgattggttg taacgaagga
     4081 agtttgcctt ataacggagc gacagaaaag aaagtaatcg actttaatga aataaaagca
     4141 gaaccagtaa cgacgataga agaagaacga agactatttt atgttgcgat gactagagca
     4201 agaaatcgtc tgtatctatg tgtacctcaa atgaaaaatt caagaaaatt gaaagtatcg
     4261 agatttatca aagaaaccgg gagtcgtgtg aaaaaaggaa agtgatagaa gagagggtgt
     4321 gacagaagtg gtcagtttca agaaagaaga aggaatgtac gaaaattgct tctcaaattt
     4381 ttgtgaaatt tcagcttatt ttcgaagaag ctatttctgg aacacagttt attcggaaaa
     4441 gggaggtgtg acaagaat
//
LOCUS       DACBYO010000147         4425 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.147, whole genome shotgun sequence.
ACCESSION   DACBYO010000147 DACBYO010000000
VERSION     DACBYO010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.147"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            690..1658
                     /locus_tag="IVD26_002804"
     CDS             690..1658
                     /locus_tag="IVD26_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6080709.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="IVD26_002805"
     CDS             1669..2484
                     /locus_tag="IVD26_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HAP6080710.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="IVD26_002806"
     CDS             2552..3262
                     /locus_tag="IVD26_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP6080711.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4425
                     /locus_tag="IVD26_002807"
     CDS             3298..>4425
                     /locus_tag="IVD26_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAP6080712.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1490 a          661 c          921 g         1353 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaat
//
LOCUS       DACBYO010000148         4396 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.148, whole genome shotgun sequence.
ACCESSION   DACBYO010000148 DACBYO010000000
VERSION     DACBYO010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.148"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..93
                     /locus_tag="IVD26_002808"
     CDS             <1..93
                     /locus_tag="IVD26_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP6080713.1"
                     /translation="RGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
     gene            complement(151..1371)
                     /locus_tag="IVD26_002809"
     CDS             complement(151..1371)
                     /locus_tag="IVD26_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP6080714.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1391..1996)
                     /locus_tag="IVD26_002810"
     CDS             complement(1391..1996)
                     /locus_tag="IVD26_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005234653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP6080715.1"
                     /translation="MKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELPLF
                     NKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVDKP
                     VMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLIDEE
                     QVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(2045..2977)
                     /locus_tag="IVD26_002811"
     CDS             complement(2045..2977)
                     /locus_tag="IVD26_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAP6080716.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3398..4258)
                     /locus_tag="IVD26_002812"
     CDS             complement(3398..4258)
                     /locus_tag="IVD26_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6080717.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1257 a          882 c          727 g         1530 t
ORIGIN      
        1 cgaggattat ataagaaaac ccgaaaagaa ggcactctct tcgggttttc ggtctgtact
       61 gaaatcaagg tattattggg aatcccagct taaatcatag ataccgtaag ggactttatt
      121 ctttatttaa aactttgcaa cagaaccttt ttattttaca gaagcactcg aaactgcatc
      181 tactgcagtt tcatcgtgtg tgctggcgct ggttactgca tctgtttttc caccatgaac
      241 agatgcactt gaaaccgcat cttcatttcc aacaagttgt tgacccgttt gttgtaaata
      301 ccactcaatg attggtttga aatcaagaat gtattcattg attccagcat actctccatt
      361 ttcatcatgc attgcttggt aattatgcac aatatatttt tctggcactt gttttggtac
      421 atgaacacgt accgcatctg ttgctccgct tcgcagttgt tgaattaccc actctacatt
      481 tttatacgat ttttctgggt gacagttggc taatggattc cctacctgac cgggcacacg
      541 agcagctaac atctctttcg cttcttggcg caaattataa tataaaaatt ggttattatt
      601 atctgcaaaa gttaattcca tcggcatcga atctaaaaag taattgattt gatccactgt
      661 caataaccca cgatttaatt tgacgtaagt atttccagaa acggcaccga ctgcttcaga
      721 agctttttcc aaccaatgat catctgacat atcaacatcg ggtattgtcg tagcaattgt
      781 tcctgtcgca tgcaaatctt ctggtggaag ctttttaggc cctgctaagg tagacacgac
      841 tttaatgaat tttacaaaac ttgctaatgt actgcctaaa aagtcaacag ttcgtggatc
      901 aatcaagcga tcttcttggt caaatgcttc ttttgctttt cccaataaaa attcatttcc
      961 gggcatcact aatgcattca cgcctggtgc gtccaaaatt tggcgcaagt gtaattgcgc
     1021 gcgtgaagtt ccttgatcgt agtaagaagc acccacaacc attacaggtt tattttcaag
     1081 tggatggatt ttaaatgata gccattcaag tgcacttttc aatcctgctg gaaccgtatg
     1141 attgtgttct ggcgtagcaa taattacccc atcagccatt aagattttgc gatttagctg
     1201 ttgaatagca ggactatttg tttgatcatc atcttgattg aacagaggta aatctttgat
     1261 ttcaatgatt tctaaattaa atagttcatg atattgtttt tggataaatg ttaataattt
     1321 acggttatat gaaagttcag ctgctgatcc gacgatacct attaatttca tctttgtttg
     1381 ctcccctcga ttaaatcgtt tcccatgaaa agctttcggc ttcacgttta tttgcttggt
     1441 gcgcatgttg caattgacta gtgattgtga caaagagtaa gaaatctttg aatagttcac
     1501 gtaattttgc gacttgttct tcatcaatga gtcgtccttg ctcatcaaag gcttggagtg
     1561 aatgacccaa taaaaattct gagcttggca taattcgtgc ctttaactct ggtgaatcca
     1621 atatttggcg caaatgtgct tgtgcgcgtg aagaacctaa cgtgccataa gacgctccgg
     1681 taatcatcac tggtttatcc acaaacggaa aaataccata tgaaagccaa tttaatgcgt
     1741 taatcaatga agcaggaacc gcatggtcat actctggtgt gctgatgatt acgccatctg
     1801 cttgttcaat ttttccagca atttctttaa caacatttgg tagttctgtg ttttcaggtt
     1861 tgttaaatag tggcagctcc ttgatttcga caatttcgat ttctgcctca tttacaaaat
     1921 aatttttcat aaactgtaat aattcacggt ttgttgaccg cgttgaattt gttcctacta
     1981 atccaataaa tttcatcttc attctctttc ctttctaaca tcgatttctg actgttcgca
     2041 cgtactaaat tttttcaaat ccttttgtat acaagaattg attctctttt gttacaactg
     2101 ctccctcgat acccggctgt tcttcaagcg ctttcaacac ttctaaagaa gatgctccaa
     2161 ataaacgtgt agtccagatt tctccatcta cagaagaatc agacaaaatc gtcaggcttg
     2221 ctacgtcatt tttaactgga aagccagttt tcggatcaat gatgtgatga tacactgacg
     2281 aaccattttg tagataacgt tcgtagattc cagaggtaac taaagattgg ttgtttagtt
     2341 taaccaccgc aagcgactct tcacgtgaac ctttaggatt tcgcaaacca atacgccaag
     2401 caccatccga acgtcttggt gattcaccaa aaacaacgat atttcctcct aagttaacta
     2461 aagcaaacgc tgcatttcgc tctcggcaat gtgtaattaa tttatctgca atgtaacctt
     2521 ttgctaacgc ccccaagtca atcatcattc ctggtttggt taaaaaaacg gttttcattt
     2581 tttcatctaa ttgaatttgg tgtggatccg ttagcagaag taactcagtt atctctgctt
     2641 ttgttggaac caatgcatct tcaaatccaa tgtgccattt ttgtacaacc ggaccaatag
     2701 caatattcag ataactattt cttgcacaac tatgtgcttt tcctaatttg atgagctcaa
     2761 aaagttcagg atgtacaatc acagcttgtc gtccagcagc ttgattgatg gccattaatt
     2821 cagaagttgc atcatgtgcg ctgaagcgat gttcataaac gtgcaaccat tcgcctaact
     2881 ctgctagtaa tcgactaggc tcttcatgcc caacttgtaa tgtaattgtt gtccccatca
     2941 tttgccagat tttcgtttct tcgatcacct gattcatttt gtaccttctt tacttgaact
     3001 acggattaca tgagtaatta gtttttattt ttgttactgt tttcacaacc agatgatacg
     3061 cctgctagat ttatttgtca accgatttta tatatttttt tatataataa ggtaatttta
     3121 atataaaatt ttatattgta aaaaaacaaa taagggaaac aaacaacaca tttttgtgtg
     3181 ttgcttattt ccctctaact atcgttttct atttgatggt taacctactt aaaataaata
     3241 ctgcaacgac aaacggagat caagcatgct ttgtaacgta ttttacgata attacgactt
     3301 tattttatta ctctatcttg ctgccatacc cgtctatccc taatcatctt tggtgaattt
     3361 tttcaaagtt agcataacaa aaataagtat tttttcctta gttaatcaat agtatcattt
     3421 ttttcatatg atttaattca tcaattaatt ttttgttttt attaatttta gcaaaagcta
     3481 gtgcatcttg aatcaattcg agcacttctg ccttcgactt atttttagcc tgtgcgttct
     3541 tcgctaattg ggcagcagct cgtgctaagt aataagtcaa atggttatcc gaacaaatat
     3601 cgattgcgta atttagtagt gcatcacttg tttccaaatc accgtcttgc gcaaaaaaaa
     3661 caccacaatg aaagacgata tttaacaccc gccagatatc ttctgttgta cgaatcggat
     3721 acgtataaat tttttcaaac actcgattga aataaacttc tgctttttcc aactcttttt
     3781 ctctagcata gaccattcca atacctgtat atgccaataa acgaaacaac gtgttggctg
     3841 tttctgccat caacaactga tcaaaatgga acaacacatc cgtaattggt gcattcgtaa
     3901 aaatcatttc aaatcctttt agatagtagt aacgtgcaat cagctcagac tcgtcaatta
     3961 ccttgggatc aatggctgct aaaatctgtg tcaattgttc atattcactc gtaatcagtg
     4021 aaaactctgc tttttctagc tgttcatcaa gttgtgtatt gatcacgttc atcgaagaaa
     4081 aaagttcaac taacggaaga ttgattcgat tacataattt gattaaaatt tttaacgaag
     4141 ggacttgacc attgttctca aatttactta atgttgcttg tgtacaaatt ccttcagaca
     4201 cttctttttg agataagttg gcagcctttc ttgccgtaat aaatttttca atgttcatta
     4261 ttttctctcc aatcagacct cacacgaaaa tcatttctgt ctcgatttta gcatgttttc
     4321 tttgggaatg ctttaggttc tgttgcaaag ttttaaataa agaataaagt cccttacggt
     4381 atctatgatt taagct
//
LOCUS       DACBYO010000149         4319 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.150, whole genome shotgun sequence.
ACCESSION   DACBYO010000149 DACBYO010000000
VERSION     DACBYO010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.150"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(17..1537)
                     /locus_tag="IVD26_002813"
     CDS             complement(17..1537)
                     /locus_tag="IVD26_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAP6080718.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(1780..1965)
                     /locus_tag="IVD26_002814"
     CDS             complement(1780..1965)
                     /locus_tag="IVD26_002814"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HAP6080719.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(1949..2131)
                     /locus_tag="IVD26_002815"
     CDS             complement(1949..2131)
                     /locus_tag="IVD26_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080720.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            2372..2590
                     /locus_tag="IVD26_002816"
                     /pseudo
     CDS             2372..2590
                     /locus_tag="IVD26_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            3085..3684
                     /locus_tag="IVD26_002817"
     CDS             3085..3684
                     /locus_tag="IVD26_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP6080721.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            3748..>4319
                     /locus_tag="IVD26_002818"
     CDS             3748..>4319
                     /locus_tag="IVD26_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080722.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIG"
BASE COUNT         1374 a          784 c          769 g         1392 t
ORIGIN      
        1 ttatttgtgg cttatattat ttacagattt cttgtatctg ctgattccat ggcaaataag
       61 cgcgtagcgc ttcaggtgtc atcgaagaca gattgggaat ctctgtaaaa agatgattta
      121 aatatttgcg gatgtttaac ccattcgcaa cagctgtctg gataatactc aatataattc
      181 catttgatct agcgcctttt aagcttttag aaaatagcca gttttttcga ccgatcacta
      241 actctttgat ggcacgctct gctcggttat ttgaaagttc caagcgtcca tcaagcaaca
      301 caatctgaag tccgtcttta tgattgactg cgtattgaac cgcctttcca agctgcgatt
      361 ttggcaaata agcaaaactc tcacaccaat gaaaaaattc agtcatcaca ggctgcaacg
      421 tttccttcct cgctacaaac ctttcttctg cgctaagctt attaaaggtc cgttcgattc
      481 gaaacatctt gtcacagaag tctaatccta ttttggcatg actttttggg gacggttgtt
      541 tacccaatgc ttcaaaaaac tttctgcgaa catgcgccca acaataaaca ttgtttaccg
      601 gcagctttcc ataggccgcg taaccatcag tatgcaagaa accgctaaat gattctaaaa
      661 aactttttgg ctcatcaacg gaacgcgaat ttgcgtgctc gtagagcaca acttgttttt
      721 cttcgctttt acctgaagca tataaccagt aaaaggtctt ttctttatga gtattcaata
      781 cccgatagct tgtctcatcc gcgtgtaaga cctcctgatt gcttaattct tgatgaaggc
      841 aattgtagat tggctctaaa accatttcac ttaccttgat atgccaatta gtgatttttt
      901 tacgatcaag agggaaacca agtgcatgcc attctttttc ttgtcgatat gccggcacct
      961 ttttaacaaa tttttcccaa atactctgtg tcacaattga agaggaacct agactattat
     1021 tgatcaacgg tttaggaaca ggcgcttttt tgatttttgt ttctcctaat gcttcacatt
     1081 ctctgcaatg ataggcatgt tggtagatga cttgtttttc tatatgggca ggaacataca
     1141 atggctcttc tctaagcctt gtcgcaccga tatcatgtaa agtatgacca cagtcttcac
     1201 acaaacaatc ggcacctttt aattcataat gaataggaac ttcaggcaga ccttctaatg
     1261 aaagtgcttt gagtcccttg cgttttctgc gtttaaaaga agataccgta atgggttcct
     1321 ggctttcttg tccagtgtgc tctggttcat taaaagttga gtcgtctaat aaatcgattt
     1381 gcccatctac gggtggtgtt tctttttttc gtccaaacaa gcgtcgattc atttcagcaa
     1441 tttgttctct aagaagagta ttttcctgtt gctggatttc aagcaactgt gttaattgct
     1501 tgatttgtac aagaagttca gattccattt ttgtcatttt tacaccacca ttctagcgat
     1561 tttcttacat ctattatacc attttatgac aacgaaaaac agacaaaatc cttgatttaa
     1621 caaggttttc gtctaatata tcgcaccttt tttcgtttct tttagcgtac atttttcttc
     1681 gattgaaagg ccagtcagta agacttcttt tctggaacgc ggccattgaa ggtacccact
     1741 ttcaaatctt ttgtacatta atacaaatcc attttgatcc tagtaaagag ccttgaagcg
     1801 atctttcttc gtaccgcaaa ataagaaaag cgcttgatcg taaacatcaa ggtcatattc
     1861 ttctataacg aaagctgcta gtccatcaat tccttttcga agatctgttt ttccacaaac
     1921 gataaaaata tgtttcaatg cagttgcatc aatgagcatt ggcattcaac tcttttaaca
     1981 aggtatacaa aagatattta tccattccat tataaataaa tatttcctta tcttccgatt
     2041 tgattctgca agctagtttt ggcttggtgt caatttgcga tttttgagcc gcacttgaaa
     2101 attgaactgg tacaatatct tttttattca ttcgtttttc tccttctata tttgatagtt
     2161 taattataga agaaagataa tcggcgtacg agatactatc ctatgacacg cttacattta
     2221 atttaatatt ttgcctcaaa ttagccacac tttttataga actaagagga aaaatgaagt
     2281 tttcttccta ttaatatagt tgtttgaaat cttaaatata gcgttttacg atgtaatggg
     2341 aagtatggtg aataaatcaa ctatgttcgt acgaagcatt tactcaacta atttaatcga
     2401 atctttcaat aaacaaatca agaaatacag ccaccgcaag gaacagttcc aaaatgaaga
     2461 gtcgatggaa cgtttcttag tctcgtcttt tgatacttac aaccaaaaat tcctaggtcg
     2521 cagtcataaa ggtttccaac aggccgaagg cgagctcgaa caaatgctga gtcaaccgat
     2581 ggagaattag aaacaatcta cagtagggaa gaaccattga cacaaaatta ttgacgctcc
     2641 caactaaaag tgtcaaaata atgatgaaat catttagttc ttataaatta gaaaagagaa
     2701 aataaatatt ccatatctac tttattggat ccgtaacatg actaaattct gaatactttt
     2761 taaagcttat catttggtaa aactgaatat aagttaatta tatagactga aaattttgaa
     2821 ttttcagaat agaataactt aaaagtactg acaaaatttt ttaaaggggc aatattaatg
     2881 ttctgagata atcaaatcct accgaaaata tcaaaaatcc aatgtgacac aatcagattg
     2941 tgtctcattc gagggaatca cacaatccca cgtggctcta ggcagaattg aatttttgct
     3001 tggggctttt tccttatatt gattttgaat gagacttatt atatgttata atgcaattaa
     3061 gtatcattgg agagggcgaa gaaaatgaag acggtagaac ctattcgaga caaaaaaaag
     3121 atcgatgcga tgaaggcaat cttggcttcg ggaaaatatg gccaacgaaa tttggttctt
     3181 ttttcgattg ggatcaacac cgcctatcgc atttctgatt tgcgtcaatt gaagctggcc
     3241 gacgtgctgg aaatttcacg cggtcgcgtg gtggtcaaag atcgattagc gatgaaggaa
     3301 caaaaaacag ctaaacataa ttcggtctat atttccaaca aattgcgaaa aacgattttg
     3361 gagtacgttc aacaggaatt tcctgatcaa ctccttcagc aagattttga cggttatttg
     3421 ttccctagtc gaaaagggac gaatgaaccg ctcaaccgcc aaagtctgtg gcgaatcatt
     3481 catgatgctg gcacggcaat cggattgaaa gacattggcc cacattccat gcgaaaaacg
     3541 ttcggttact ttctctataa acaggggacc aaaacagaaa tcattcagtc cttgttgaac
     3601 cattcttctc agcgcgaaac attgcggtat attggtatta cacaagaaga caaagataca
     3661 gctgtaaaaa gcttagattt ataatataaa agttaagttt aaacatggat agttttaaat
     3721 tagtagattg agtgttggga ggaaagaatg agtacattat atattatagg aaacggtttt
     3781 gatttaagtc atggtttaaa aactagatac actgattttt caaaatgggt tgaaaaaagt
     3841 catagtgaaa tattcgataa aatagacaca atgataaatg aaaataatga ggtgagaagt
     3901 acagctgatg ataagatagg ttggtttaat tttgaaagta gtttgcatga gttaattcaa
     3961 agtccagtct ttgaagatta tgtagaagag tctaaggatt atctcatagg ttatggacat
     4021 gaagattggt cagattctgc ccatcatgat tttcaaaata tggtttatga ttatgttgtt
     4081 tctctagaag aattacaaca acttttcaag gaatggatac gcaaagaaat acagccgaca
     4141 atagaacata aaattccaaa ataccaattt tcgtccgatg tactattctt tacattcaat
     4201 tatacagatg ttttggaaat tctatacaag caaccgaaag aaaacatata tcatattcat
     4261 ggcagttatg acgatataat aatcggccac tccgagaatt ttgacaactt tataggaga
//
LOCUS       DACBYO010000150         4199 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.151, whole genome shotgun sequence.
ACCESSION   DACBYO010000150 DACBYO010000000
VERSION     DACBYO010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.151"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..1091
                     /locus_tag="IVD26_002819"
     CDS             <1..1091
                     /locus_tag="IVD26_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAP6080723.1"
                     /translation="CVNDMHRAGLETMLMNYYRNIDRTKIQFDFLTHRPYKSDYDEEI
                     ISLGGKVYYAPRLYPQNYPKYFKWMEQFFKDHPEYEIVHSHIDAMSYLPLKAAKKAGI
                     PIRIAHSHNTSIDRDFKYLLKQYYRCKLTSVLTHEFSCGKVAGDFLFRNDKFTLIPNA
                     VDAKKFYYDESIRNDVRMKLGISSQTFVMGHIGRISYSKNHRFLIEIFKEFHAIKNNS
                     VLLIIGTGDMEEEIKNYAKKSGIDDDIKFLGNRNDIEKFYQAFDVLMLPSLFEGVPLV
                     GIEAQFADLPCFFSEKVPTEVAFSDKTNFISLNQSAKEWAREIANVDISHRDSERSIL
                     IKADYNIQTAYKILESKYYELFELIQRG"
     gene            1097..2119
                     /locus_tag="IVD26_002820"
     CDS             1097..2119
                     /locus_tag="IVD26_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP6080724.1"
                     /translation="MTQKHSSIKRIIHRISEELNATRRIAKITSWKEAFATLQAKIDI
                     QVMNRNGYNESKKQKEHLLKKHEVMLKYYEKTFSDFLKTYDYSQNQIINQSKSPYSNC
                     IWVCWWQGLDQSPEIVKACVKSIKRNAGKHTVIILTEDNYRQYVDIPKWVEEKKNKGI
                     ITRTNYSDLLRLSLLAKHGGLWLDATFYCTKPIPDEYFDIDIWSIRRPDYAHASVASG
                     YFAGYSLACNQESRWMFAIIRDFFLNYWKNNDMMVDYLMIDYMIVLAQRINHEIAQTF
                     DKIPSNNPLCDELIKNLNNIYDEKVWNLLKKDTLLFKLTWKQSFKKQKDDKVTFYGML
                     VENKLL"
     gene            2141..3196
                     /locus_tag="IVD26_002821"
     CDS             2141..3196
                     /locus_tag="IVD26_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP6080725.1"
                     /translation="MKHKVSVIVPIYNVEKYLRKCVDSLLSQTLKEIEIVLVDDGSPD
                     ASGEIADEYQKKYSNVKTIHRENGGLGPARNTGIENATGEYVAFLDSDDWVESDMYEK
                     LYLVASKENADIVVSGHCDFANDKAMVKKQHPLSGNVYDTPNSIKNVRKNLFGHSPKD
                     QEVEAFPMSVCMSLYNKNLLDKYRLRFEKILSEDTIFNLNAYDVANKIAFTEYTDYCY
                     RKEEQESITKSLSPNKQTEFKEFLITLKAIASKEDLECQIRAKRMAIDYCRLYVGLVD
                     DANLGIKEKRKYIKKFIEDEGLIQCWKGYPTNTLPFQQKFFHKMLECKCYTILLLLSR
                     IRKIIKNMTRKKLFIIL"
BASE COUNT         1624 a          437 c          765 g         1373 t
ORIGIN      
        1 agtgtgtgaa tgatatgcat cgtgcagggt tggagacgat gctaatgaac tattatagga
       61 atatagatcg aactaaaatt cagtttgatt ttttgacaca tcgtccatat aaaagtgatt
      121 atgatgagga aataataagt cttggaggaa aggtctatta tgcaccgaga ctttatccac
      181 aaaattatcc taaatatttt aaatggatgg aacaattttt taaggatcat ccagaatatg
      241 agattgttca ttctcatatt gatgcgatga gttatttacc tttaaaagct gcaaaaaaag
      301 ctgggattcc gatacggata gcacatagcc ataatacatc gatagataga gattttaaat
      361 atcttttaaa gcaatattat cgatgtaagt taacgtctgt tttgacacat gaattttcat
      421 gtggaaaagt agcaggtgat tttttgtttc gaaatgataa attcactttg attccaaatg
      481 cagtggatgc taaaaaattt tattatgatg aaagtattag aaatgatgta cgaatgaaat
      541 taggaatttc aagtcagacg tttgtaatgg gacatattgg aagaatttca tattctaaaa
      601 atcatcgttt tttgattgaa atttttaaag aatttcacgc tattaagaat aattccgtat
      661 tattaattat tggaactggt gatatggaag aagaaataaa aaattatgca aagaaaagtg
      721 gcatagatga tgatattaaa tttttaggaa atagaaatga tatagaaaaa ttttatcaag
      781 catttgacgt attaatgttg ccatcattat ttgaaggggt tccgttagtg ggtattgaag
      841 ctcaatttgc agatttaccg tgtttctttt cggagaaagt tcctacagaa gttgctttca
      901 gtgataagac caatttcata agtttaaatc aatcggcaaa agaatgggcg agagagattg
      961 caaatgtaga tatctctcat cgagattcag aacgttcgat tttaataaag gcagattata
     1021 atattcaaac agcatacaaa atcttagaat caaaatatta tgagttattt gaattaatac
     1081 aaagaggtta aagaatatga cacagaaaca ttcaagtata aaaagaatta tacatcgcat
     1141 atccgaagaa ttgaatgcaa caagacgaat tgcaaagata acatcttgga aggaagcatt
     1201 tgccacgtta caagctaaaa ttgatattca agtcatgaat cgtaatggat ataatgaaag
     1261 taaaaaacag aaggaacatt tattaaaaaa acatgaggta atgctgaagt attatgaaaa
     1321 gactttttca gattttttga aaacatatga ttatagtcaa aatcaaataa ttaatcaatc
     1381 aaaatcacca tattctaact gcatttgggt ttgttggtgg cagggattgg atcaatcgcc
     1441 ggaaattgta aaagcttgtg taaaatcaat aaaacgaaat gcagggaaac atactgttat
     1501 aattttaaca gaagataatt atagacaata tgttgatata ccaaaatggg tggaagaaaa
     1561 gaaaaacaaa ggaatcatta cgagaacaaa ttattctgat ttattaagat tatctttgct
     1621 agcaaaacat ggaggtttgt ggttagacgc cacattttat tgtacaaaac caataccaga
     1681 tgagtatttt gatatcgata tttggtctat taggaggcct gattatgctc acgcatccgt
     1741 agcatcagga tattttgcgg gttattcatt agcatgtaat caagagtcta gatggatgtt
     1801 tgctataatt agagactttt ttttaaatta ttggaaaaat aatgatatga tggtggatta
     1861 tttgatgata gattatatga ttgttttagc acagagaata aatcatgaaa tagcacagac
     1921 atttgataaa atacctagta acaatccatt atgtgacgaa ttgattaaaa atttaaataa
     1981 tatatatgat gaaaaagtat ggaacttatt aaagaaagat actttactgt ttaagttgac
     2041 atggaaacaa tcttttaaaa agcaaaaaga tgataaagtt actttttatg ggatgttggt
     2101 agaaaacaaa ttattataaa tattagaggt ataaaaagtt atgaaacaca aggtaagtgt
     2161 gatagtacca atttacaatg ttgaaaaata tttaagaaaa tgtgtggata gtttattgag
     2221 tcagacatta aaagagatag aaatcgtatt agttgatgat ggttcgccag atgcttcggg
     2281 ggaaatagca gatgagtatc aaaaaaaata ttctaatgta aaaacaatac atagagaaaa
     2341 tggggggtta ggaccggcaa gaaatacagg aattgagaat gcgacaggag aatatgtggc
     2401 ttttcttgat tcagatgatt gggtagaaag tgatatgtat gaaaaattat acttagttgc
     2461 gtccaaagaa aatgctgata tagtagttag tggacattgt gattttgcga atgacaaagc
     2521 tatggtgaaa aagcaacatc ctttgagtgg gaatgtatat gatacgccta atagtattaa
     2581 aaatgtacga aaaaatttat ttggacatag tccaaaagat caagaagtag aggccttccc
     2641 gatgtcagta tgtatgtctt tgtataataa aaatctgcta gataaatata gactaagatt
     2701 tgaaaaaatt ttatctgaag atacaatttt taacttgaat gcatatgatg tcgcaaataa
     2761 aattgctttt acagaatata cagattattg ttatagaaaa gaagaacaag agtctattac
     2821 aaaaagttta tctccaaata agcagacgga atttaaagaa tttttaataa ctctaaaagc
     2881 tatagcatcg aaagaagatt tagaatgtca aatcagagca aaacgtatgg caattgatta
     2941 ttgtaggctt tatgtgggct tagttgatga tgcaaatttg ggaattaaag agaaaagaaa
     3001 gtatataaaa aaatttattg aagatgaggg attaattcaa tgttggaagg gatatcctac
     3061 aaatacgcta ccatttcaac aaaaattttt tcataaaatg cttgaatgta agtgttatac
     3121 aatattgttg ttgttaagta gaattagaaa gataattaaa aatatgacca gaaaaaaatt
     3181 gtttataata ttataaacta aaagtatatc aaataataga aattaacaag ttacaaaaaa
     3241 atattataaa gaataatatt ttctaaaaag taaactatag taatgtggat tatcaccttc
     3301 caacagtata taaaatgagc gtaaaaacgg ctatttttgc cttaacaacg atttttttgt
     3361 atacaaatac gatatgctca ttaattattg gaatttgtag tgctgtttaa attaatgaag
     3421 gtgtaattat atgagtgatc attttgaaaa agtttgttga gaagatgtgc ttctagtcat
     3481 gtgatgggag aaaataattt aactgttaga gtgaatagtt aaattattct ggttatatga
     3541 aaaaagtagt ttctaaaata atcttgcagg gattaactta aagaaattga gagaatagtt
     3601 tctttgaaat ttctatatac aatgagaagc tgaaatttac ttttatttga tgactggaaa
     3661 tagaaattaa atatattgta ttgttacatt aaagaaaact tgtatggaaa aatcagtaca
     3721 ataccattat ttaatgttct tcacttaaag cgcaaaaaat atcagtttat taaactcgta
     3781 tatagaacaa atatatgtag acggggcgaa acgatgagtg taaaaaaaat gctatttatg
     3841 gtaagtacaa taattgtatt aacatcccga ttttggggaa ttaatactag tttatctatg
     3901 cgatatttta ttatggcaat atgggattta tattttatgt taagctattt ttcttatcgt
     3961 gagaaaacat ataaaaaata cgttatcaag aataactttt ggttgactat aatgccgttt
     4021 gtgatatttt ctatctatac tctaataata tggggaattg gttcaaatgc agaatttgaa
     4081 aattttataa agttatgttc cacgttgctt tatttaattc ttgcatatgg ttacgcatgt
     4141 acagcatttt acttatttaa ggcagaagga attgatttta ttttttggtc aggtgttat
//
LOCUS       DACBYO010000151         4157 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.153, whole genome shotgun sequence.
ACCESSION   DACBYO010000151 DACBYO010000000
VERSION     DACBYO010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.153"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(64..1836)
                     /locus_tag="IVD26_002822"
     CDS             complement(64..1836)
                     /locus_tag="IVD26_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6080726.1"
                     /translation="MRMQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINM
                     VPAFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLR
                     MQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVM
                     LLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEI
                     NSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLL
                     TGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSP
                     LKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDY
                     DEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAA
                     RLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLD
                     AENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSE
                     IYKNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(1790..3544)
                     /locus_tag="IVD26_002823"
     CDS             complement(1790..3544)
                     /locus_tag="IVD26_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6080727.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLK
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(3654..>4157)
                     /locus_tag="IVD26_002824"
     CDS             complement(3654..>4157)
                     /locus_tag="IVD26_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAP6080728.1"
                     /translation="SIMVSSIGGAFGHSISPGIFGLLSGIIFVYISYNYPRKGIFTIY
                     TIVLLLFFTLMGGAYLPWFISSISMAILADIILSVFGYDRAIPQVASWALMQLGSAAG
                     QWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGIWGIISVLVVASLSMIGVLIGRK
                     VLKKYKK"
BASE COUNT         1395 a          794 c          582 g         1386 t
ORIGIN      
        1 tctttttgaa aaagaattat aactatatcc caaaaattgt aggttaattt aaagcctatt
       61 tcatcatcgt gattgagctt ctttttcata gacgaatttc tcagatagtt tagttttctt
      121 tatgagattt ttgtatattt ctgaccttcg atacaactca ctatgagtac cttgatcaac
      181 tatttttcct tgatccatca ctacaatttt atttaccttt tcaatagact tcaagcgatg
      241 cgatataatt agtactgtct tatcttgtat taaacgattt aaactttcct gaatacgttt
      301 ttcattttcc gcatctaaac tggcagtaat ttcatctaaa attaaaattg gcgcattttt
      361 caaaaaagcc cgtgctatgg ataggcgttg tcgctctcct ccagaaagtg aacttccgtt
      421 ttctccgacc aatgtatgat aaccgtcagg tagtttttca ataaagtctt cgcagttagc
      481 taaacgagct gcttttttca cttcctcatc tgacgcttga ctatttccaa tacgtatatt
      541 ttccaaaata cttgtattaa acaaagttac ctcttgaaaa acaatagcga ttttgctaaa
      601 caaagaagct ggagatacac gtttaatatc atacccatca attaaaatac agccttcatc
      661 ataatcatac agtctagaca ctaatttcaa gatactagtt ttcccggaac cactagcacc
      721 tactaacgca gtcacttctc cttgtttagc cgtaaaagag atatgatcta aaattggggt
      781 attgttatca tatgagaaag agacatctcg caactcaatg tcaaaagatt tcagaggact
      841 atctgatccc tcttggatac tggtttcctt catagctcta attcgctgta ttttaggagc
      901 taaataaaat atttcaagca ctgcttcttt catagaatcg aaggaatcct ttatttttat
      961 tgcggctagt aagtaaccaa cgacgtagag tatagtcact tcacccgtta acagtaagtg
     1021 aacacctact agaatgacta ctgctaaact aacatatgag aaaatagagg ataaggccat
     1081 gactgaaaaa gtacttaatt ctacctttaa atgaatcctt tcactctctt ccattttttt
     1141 gaaaagtctg tcttgaactt ttttagatag attaaagcta ttaatctctt gctgcaattc
     1201 tatagtttct tgaaattctt ccgagttttc tctcaaagta tcgtaatatt tagtattggc
     1261 tttcgtttgg gatttctttg ataacaagat taagacaaaa ctaaataacg ttggcaaaat
     1321 aacagctaat cccattttga cattaccaac caaaagcatc actgaaataa aagggaaaaa
     1381 cagagccata ccgccggctt taggtattgc atgactcatc gcatgctcaa taccttcaac
     1441 gtcagacatg atagtttgag ataaatctga taaattatgt tttgaaaaat aggataatgg
     1501 taaatttgac aaatcgtctg caatttgcat tcttaaatgc gcactttctt tataagtact
     1561 attatataag ttttcatact ccctatctaa caaccaatac atgaaaagca aagtaacgaa
     1621 cgatactgta aaataaagcc aaggcggctt tacattttct aaaactaatt cgtctatcag
     1681 catcattata atgaatgctg gtaccatatt aatgcagtat acaaaaaagc tagaaataga
     1741 tgctttaacc aaatcttctg cgccctgatt agttaaagcg aatttgtttt tataaaaact
     1801 tttcattgtc aagcctccaa tcatttgcat tctcataatt agtgaccaat tgtttataca
     1861 cttgatgttt agccattaat tcattatgat ttccacgttc tactattttc ccttctgaca
     1921 agacaagaat ttcatctaca gatttaatgc tggataatcg atgagctatc ataataactg
     1981 ttttttcttt catcagatgt tgaaaagcct tttgtagttc atactcatta tctggatcaa
     2041 tagatgcact ggcttcatcc ataataacaa tctttgcatc ttttaaaatt gctctggcaa
     2101 tagctatacg ttgtttttct cctcctgaca gataaactcc tttactacca attaaggtat
     2161 gctctctttc gggaaatttt tctaaaatcg attcgcaacc ggctaatctt agcgcgtcaa
     2221 atactttact tgctggcgct tgaggatttg ctatagaaac gttatcgtaa atactctgat
     2281 tgaatagttt cgtatcttga aagacaaaag caattgtgtt aataattgtg tcttttgaat
     2341 agtgatttaa aggcttacca ccaattttaa tctgtccctt atccacattg tagaaacctg
     2401 aaattagttt agctatcgta ctctttccgc ttcctgattt tcctactaat gcataaattc
     2461 ttttttgttc taaaactaag ttgaaatttt ctaaaacaca ctcttctttg tatgaaaagc
     2521 tgacattttc aaatgcaatg tcacaatttt taatctgtgt ctcgttccca tattttagtt
     2581 ggtcttgctt catttctaaa taaagggagt ctagtgtttc gactgcatat cttgcttcaa
     2641 acaagtgcat acttacatac attattctca tgaaagaaac aaaaataatt ccacttaaaa
     2701 aaaacaacat caacaagtca acagctaata tcttgggagt ggtaagagaa gttataaaaa
     2761 aggttatagg aactatcaaa atgcaaacta tgccaaaaaa tagccattga aaaagaacaa
     2821 aaggtgtttt cccactcaaa gaatacttat atgcaaactt agcataatcg ttaattgctt
     2881 tattcaaggc tttaaatgat gttactttag caccaaatat ctttataact tgaattcctc
     2941 ggatatattc taccgtttca gagcttaaca catctaacga ttcttgatat ttttgaataa
     3001 aatttgtatt ctctgtcatt ttctttaaca agaatacacc aattactaac atggcgatta
     3061 gaaccaatcc aattttaaaa ttaatgaaaa agcctaaggc aactgataaa acaggtgtta
     3121 ctatggcttg agcactatct ggaatcaagt gagcaattgc catatgtgtt ttagccgcgt
     3181 tgtcatcaat tgtctttcga atatatcccg aagaatttaa atcaaaaaaa cgaaaacttg
     3241 cttctgttaa accgctaatt cccttttttc tcaaattagt ctctaagcga aacccaagga
     3301 tatgagaaaa taagccagaa aaaatataaa ataaagctcc taaagttaac caagcaacag
     3361 tttgaaccgc ataactctta gctaaatatt catctcctac aataattaga gacttaagaa
     3421 atttgtaaat actgtaatat ccatagactg ttaatacgac agaaaaatca gaaaataaag
     3481 tggctaacca tccgtagtat ttcattttag ggacataact aaataatttt ttgtatactt
     3541 tcattttttc ctcccccgca ttcaatttct tctcttattc gtttacaact gttaatgctt
     3601 tccgtaatag cgtaaattag agatgtacaa acagatagaa ggtaaactac gttctatttt
     3661 ttgtattttt ttaagacttt tcttccaatc aatacaccaa tcatagataa acttgctaca
     3721 actaacactg aaatgattcc ccatatacct accgcatagt ggatcattgc atccattgtt
     3781 gcagcagatt gtcctttatc tatccaatct tgacgaaaac gatctgtaaa gaaccatata
     3841 ggaatccact gtccggcagc actgcctaat tgcattagag cccaagacgc aacttgagga
     3901 attgctcgat catatccaaa tacagataga ataatatcag ctaagatcgc catactaatc
     3961 gaactgataa accaaggtaa gtacgccccg cccattaacg taaaaaataa caataaaaca
     4021 attgtgtaaa tagtaaaaat tccttttcta gggtagttat agctaatata aacaaatatg
     4081 attccagata ataatccaaa aatccctggg gatatgctgt gaccaaacgc cccaccaata
     4141 ctactaacca ttattga
//
LOCUS       DACBYO010000152         4144 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.154, whole genome shotgun sequence.
ACCESSION   DACBYO010000152 DACBYO010000000
VERSION     DACBYO010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4144
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.154"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            58..912
                     /locus_tag="IVD26_002825"
     CDS             58..912
                     /locus_tag="IVD26_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP6080729.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1009..3258
                     /locus_tag="IVD26_002826"
     CDS             1009..3258
                     /locus_tag="IVD26_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP6080730.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3261..>4144
                     /locus_tag="IVD26_002827"
     CDS             3261..>4144
                     /locus_tag="IVD26_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6080731.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTG"
BASE COUNT         1467 a          586 c          770 g         1321 t
ORIGIN      
        1 taataatata aacataataa aacaaaaatt atccaaatct aacataggag ggtggatatg
       61 gaaaattcta tatatttagt aacagaacct aacactcagc tgaaagattg ttactttaat
      121 ttttgtgggt attcaaaaac agaacctaga catagttttg gaccagctat tcgagaacaa
      181 tacttaatac acatagtgct agaaggtgaa ggctattatt caattaatga tcaaaaatat
      241 tttctgaaga aaggccaagg atttgttatc ccaccaggag tatctacttt ttatcaagca
      301 gatgaaaaaa atccgtggtc atatgtatgg ttgggtttaa gtggcaatct tgtagaatac
      361 tatctaaaag aaattggtgt tggaaagaat catcttacct ttaaagtcga aaatttaaat
      421 tcatttaaag gattaatttt tgaaacttta tcgtatgatc aggacaatct agtcagtgaa
      481 ttgtccagac aaaaacaagt ttataaattt ttagaactcc tcttaaattc agctagttat
      541 ctgaacgaag ggataattac taaaaagatg aatccttttg ttcgtcaaac aattgaaata
      601 atacgtgaga atgcgtatca aaaattatct gttaaagata ttgctgtcag tctatcgata
      661 cacgaaaatt atttatcacg attgtttaag aatgatatgg gaatatcaat aaaagagtat
      721 attagtgaaa tcaaaatttc tattgcaaac gatctgttat catcaactga atattcaatc
      781 cagcaaatca gtgacaagat aggattctca acagtacaat ctttttctaa agcctttaag
      841 aaagcaaatg gtgtttcacc gggagtatat cgaaaacgta gattaggtct aggaatcatt
      901 aatggtgaat aaactaaaca tttgattttg ataaatattc gttactttaa acgcttacta
      961 tttatgtgag cgttttttat aatgcaataa agaaacggag gagagcttat gtataaggat
     1021 aatgaaatga atattattta tcgatcagaa aaccaacaat ttcatttgtt taatcaggag
     1081 ataagttaca tttttaagat atcggaagat ggtaaattat tgcatttata ttatggtgag
     1141 aacttaccag ataatgacta tagtcatcta attgagatgc atcatcggcc tatgacaacc
     1201 tatagaaatg aaaacgattt gctatattcg ttagagcact taaaacaaga atttcctgaa
     1261 tatggtacaa cagattttag acatcctgct atttcattac tacagaaaaa tggctctcgc
     1321 ttatcagatt ttgtctatca agggtacgaa gtggaagaag gaaaacctaa actagaaggt
     1381 ttacctgcta cctatgttga taataatgat gaaagcaaaa cattgaaagt ttatatttta
     1441 gattcagtta caaatgttca agtagaatta ttatatacaa tttatagaga ttatcctgtt
     1501 attactcgta gcgcgcgagt tatgaataaa ggaaaagata ttcaaataat cgagaatatt
     1561 agcagtttat cattggattt acccgatgca aattatgaat ggcaacaatt atctggtgct
     1621 tggggtagag aaagaactat taagtcgcgt actttacaac aaggaattca atcaatcgaa
     1681 tctactcgag gtatttcaag ccatcagcat aacccatttg ttactttaaa aagaaaaaat
     1741 actgatgaaa atcaaggaga agctattggt gcagcactag tttactcagg aaacttctta
     1801 attcaagcag aagtagatac atgggatgtt actagactac aagttggcat caatccattt
     1861 ggatttaatt ggaaactcaa tccaggagaa atatttacag caccagaagc gattctggtt
     1921 tattcaagta agggtttaaa tgccatgagt caaacttttc atcaactatt tagaaaacgc
     1981 ttagctcgtg gtaagtggcg agaaaaagac cgtcctgtct taattaataa ttgggaagca
     2041 acatattttg attttgacga agaaaagttg gtaaatattg ctaaaaaagc atttgatgtt
     2101 ggtattgaat tatttgtatt agatgatggc tggtttggag aaagagaaaa cgattgtgca
     2161 ggattaggag attggcatgt aaatcctaaa agactaccta gaggaatcgg cagcctttca
     2221 gaaaaaattc gtagttttgg tatgaaattt ggtttatggt ttgaacctga aatggtgaat
     2281 aaggatagtg agttatatcg cacacatccg aattggatta tttctacacc taatcgaaaa
     2341 cctaatcatg gtaggaacca atatgtatta aattttgggt tagatgaggt tgttgaaaat
     2401 attttcgatc aaatgtgtaa aatcattgat gaatcaaact tagattacat taagtgggat
     2461 atgaatcgtc cattgactga tgtatttgac agtcacttgt cagcagatca acaaggagaa
     2521 gtattccaca gatatgtact aggcgtatat cgcttatatg aaaaacttat aacaaaatat
     2581 cctaacatac tatttgagtc ttgttcatca ggtggtgggc gctttgatcc tggaatgctt
     2641 cactatgcac ctcaagcttg ggctagtgat gattcagatg caattgaaag gttaaaaatt
     2701 caatatggaa ctagtatgct gtatcctctt tcgtctattg gtgctcatgt atcaattgtt
     2761 ccaaatcatc aaacaaaccg tataacacct ataaaaacta gaggaaatgt agcttttttt
     2821 ggtgcatttg gatatgagct tgacttaaat gaattaagtg aaggcgattt gaggattgta
     2881 aaagaacaaa ttgcctttta taaaaaatat agaaccataa ttcataatgg tactttttat
     2941 agactattat caccattcga tgatgataat caaaccgcgt ggatggttgt tagtcatgat
     3001 aagaaaacgg ctattgttgc tcattataaa acattaaatg aggtaaatgc tccttaccgc
     3061 cgactgaaat taaaagggtt agataatgac ggactttata atgtaggaca aaatagtttg
     3121 cgatctggaa tggaattgat gagagcagga ctagtctgtt cagatgcatc tagtggacaa
     3181 ataaatgatc agaatcgacg cccagaaaca tttgattttg attccaagat ttgggttata
     3241 acacaggagg aaaagtagag atgaataacc aaaaaagctt acttcaaaaa ggagcaatct
     3301 taagtatttc actaatgtta acaagctctc aagcaattaa tggtgttatt ccacaaatga
     3361 aacagtcttt ggggatatca caaagtcaaa gtgaactttt aggaactgca ccaagtataa
     3421 ctgttatttt gtttatctta ttatctagtt actttgccaa aagaatagga atgaaaaaga
     3481 caataatttt aggtttatta ttagctggta taggaggaat tattccagta tttacagcta
     3541 ccttccaaac cgttcttatt agtcgagtaa tattaggtgc cggtttagga gtatataatt
     3601 cattggctgt gacatatatc agctctttat actctggcaa tactagagca acgctattag
     3661 gtattagaaa ttcaatggaa gctttaggtc agacaatcct tatttttctt gctggagttt
     3721 tagtgaacat taattggacg gcttcgtttt tagtctatgc aattgcgttt cctgtagctc
     3781 tcttattcgc gctaaaagtt cctgaaatta gagatgaaaa tagtgacata cctgaaaatc
     3841 atgtaaaaga aaagatgaat ccaatggttt ttgccctagt tctatttgca atcttactcg
     3901 taatgaatag tattgctatt tctgtacgat ttgcatcaat tgcaactgaa attaaagggg
     3961 taaactttaa tgctagtaac tatttagctc taatgcctat cttaggaata ctagcaggat
     4021 ttatgtttgg accaataaat aagtggatag gaaaaggaac cctatacttg ggaattatat
     4081 tctttataat ttcaaatttg ttaattgctg tgtcaaacgg taatatgacg ttcctgctaa
     4141 cggg
//
LOCUS       DACBYO010000153         4130 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.155, whole genome shotgun sequence.
ACCESSION   DACBYO010000153 DACBYO010000000
VERSION     DACBYO010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.155"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..354
                     /locus_tag="IVD26_002828"
     CDS             <1..354
                     /locus_tag="IVD26_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HAP6080732.1"
                     /translation="RQTAEICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFG
                     PSIVKAYQAPLPHVNIMPTGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSR
                     VASKYIDKFYEIKNY"
     gene            474..1850
                     /locus_tag="IVD26_002829"
     CDS             474..1850
                     /locus_tag="IVD26_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6080733.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVNWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            1860..2654
                     /locus_tag="IVD26_002830"
     CDS             1860..2654
                     /locus_tag="IVD26_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP6080734.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            2673..>4130
                     /locus_tag="IVD26_002831"
     CDS             2673..>4130
                     /locus_tag="IVD26_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011609746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAP6080735.1"
                     /translation="MKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGSSR
                     DKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGACTD
                     GTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISSRS
                     FGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWDNS
                     FGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGKLG
                     FNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKGII
                     TDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQAIT
                     LVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFEVE
                     KYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTK"
BASE COUNT         1454 a          493 c          818 g         1365 t
ORIGIN      
        1 cgacaaacag ctgagatttg taatttatat caaattcctt atttaccagg ttgtatgaca
       61 attactgaga taaaggaggc acttactgct ggcgtagata tcattaaact attcccaggt
      121 tctgcttttg gtccatccat tgtaaaagcc tatcaagctc cattaccaca cgtaaatata
      181 atgcctactg gcggagtaag tatagagaac ttagaagatt ggtttgaagt aggagttgtt
      241 gcagttggtg taggtgggaa tttattggct tctgttgaaa aaggtgattt tgaagaagta
      301 agtcgagtag ctagtaaata tatagataag ttttatgaga taaagaatta ttaggagaaa
      361 aaacaaataa tactctgaaa tgtaaaaaat aaatactgac tctttacgct tcagagtata
      421 gtacgtactt tcatcagaat gaaaacgctt aacaacagaa gggagagaat tgtatggaaa
      481 gaaaatttgg tataagagac aaaataggat atatgtttgg agattttgga aacgatttta
      541 ctttcatttt tgctagttct tttttaatga tcttttatac aaaagtattg gggataagcg
      601 gagctgccgt tggaacatta tttttagtag caagatttat cgatgcagtt actgatgtaa
      661 ctatggggcg tattgttgat agatcgaaag caactaagca gggtaagttt aaaccgtgga
      721 ttttaagaat gagtggtcca gtcgctttag caagtttttt aatgtatcaa acttctatga
      781 tttcagcttc tatgagcgtt aaggtagtat acatgtatgt tacgtatata ttatggggga
      841 gtatttttta cacatctata aatattcctt atggatcaat ggcatcagct attacttcta
      901 ttacagaaga aagaacaatg ctatcgacat tccgaaatgt tggagctact ttagcaagtt
      961 tggtcattgg tgtattaaca ccattattta tttatacaag agatgattca ggcgctcaaa
     1021 tagttcgtgg tggatcaact tttacaattg ttgcgggaat attttcgata tgtgcactta
     1081 tttgttattt aatatgttat aaactaacta ctgaacgagt aagaattgac caatctcaat
     1141 acaaagtttc attgttaaaa tctttaaaag ggttagttaa aaatagggca ttactttcta
     1201 taattggtgc ggctattttc ttactccttg ctcaattatt aattatgagt atgaataatt
     1261 atgtatttcc tgattactat aatgatgcac agggaatagt tttaatgaat tttatcaatc
     1321 ctattttggt tttaatagtt gtttcgcctt taactttgtt tttaagtaaa aaatatggaa
     1381 aaaaagaact ggcatcagta ggaatgttct tttcagcaat agtatatttg atcttatttt
     1441 tgataaaagc tagtaatatg tatgtattct taattcttag ttcggttggc tatatgggtt
     1501 tgggtgtgtt taatactgtt aattgggcaa atattactga tgttattgat gatcaagaag
     1561 taaagtctga tcaaagagaa gatgggaccg tatatgcggt atattctttt gctagaaaaa
     1621 taggtcaagc tctagctgga ggcgtcggag gttggactct ttctattata ggctatgact
     1681 ctttagcaaa tgtacaaacg ggagatgttt tagaaaagtt atataacgct tcaacattaa
     1741 ttccatcaat ttgttttctg attgtaggat taattttatt tttcctttat ccattatcta
     1801 aagataaagt cttagaaaat tgcgagcttt taaaacaaaa acataaatag gagagaaata
     1861 tgaataattg gatattttgt attgattcag atggctgtgt tatggatacg atgacttata
     1921 aacacaatct ctttttcgga ccaattgctg cagagatttt tgatgttcat catagagaaa
     1981 aattcctaca ggattggaat aatattaatt tatattcaga gactcgtgga ataaacagat
     2041 ttttaggttt agttaaaaca ttagaaaaaa atgatgtaac atcgattaat cgattaaagc
     2101 actgggtatc tctaacaaaa gaattgtcta atccatcttt gaagagggaa atagaatatt
     2161 ctcagtcaga ggatttatta aaagctttaa aatggtcgga agaagtcaat caacagatta
     2221 gtcaagcaaa aggattagat aaaccctttt taagtgctag agatactata aaagctctga
     2281 aaaaatatgg gaagataatt attgtaagct cagctaataa ggaagctgtt caagaagaat
     2341 gggaaagaca tgaattatta tcattagttg atgaactgtg ttgtcaagat aaaggaaaaa
     2401 aagaagatat tattcgaagt gtaattgaaa atggttgtga tttggataag atattaatga
     2461 ttggtgattc tcctggtgat ctagaagctg caaataaaaa taaagttttc ttttatccta
     2521 ttttggtcaa taaagaaaaa gaatcatggg aaaacttaag aactgatgtt ttatttaaat
     2581 gtttatcggg agattatgta gatattgaac aaaaatatat agatactttt tggaaaaatc
     2641 ttactaataa gtagaggaga aagaaaatga ctataaaagt agatttacga aaaaaaccat
     2701 ataatttaga tgaagatgct atttcttgga ttgaagagac gattgattct atgactttgg
     2761 aagaaaaaat aggtcaattg tttgttaata tgggatctag tcgtgataaa aattacttga
     2821 gtaatatggt caatcagtac catattggag ctgtacgata taatccagga actgctgatg
     2881 aggtatatga tcaaaactat atcttacaaa cagaaagtaa aattcctcta ttaattgctg
     2941 ctaatacgga agcaggtggt aacggagctt gtacagatgg tactgaagtt ggtgtagaag
     3001 taaaaattgg tgcaacaaat gatgcgaaat atgcttatga attagggaga gtttctggga
     3061 ttgaagcatc ggctattgga tgtaactgga gttttgctcc tattgtagat attaatagaa
     3121 attggagaaa tcctatcatt tctagtcgat cttttggaca aaaccctgat aaagttttag
     3181 aacttagttt agcttatatg aaaggtattc aggagagtgg aattttgcct gcagctaaac
     3241 atttccctgg tgacggtatt gacgaacgag atcagcatct atcttttagt attaatagtt
     3301 taggtacgga agaatgggat aattcttttg gaaaagtata ctcaggctta atagaagctg
     3361 gattaccttc aattatggca ggtcatatcc atatgccagc ttattcaaaa cattttaatc
     3421 ctgatctgaa agatgaagat ttacttcctg caactttatc aaaagaatta atcactgact
     3481 tacttagagg aaaactcgga tttaatggat tagtagttac tgatgctagt catatgttag
     3541 gaatgactgg ggcaatgaaa cgatcagaat tattgcccac ttctattgca gctggatgtg
     3601 atctatttct attttttaat gatccagatg aagactttaa ttatatgatg gaaggctatc
     3661 gtaaaggaat tatcactgat gatcggttat tagatgcctt aaaaagaatt ttagggttaa
     3721 aagctaaatt gggattacac aaaaaagcaa aagaacaaat tttattacct aagcaagaag
     3781 ctctggaaaa aattggttta attgaaaata aatcaatttt taaagaggtg gctgaccaag
     3841 caattacatt agttaaagat aaacaagata tttggcctat tgtaccagaa aaatataaaa
     3901 ggattttact agtagatgta catggggtaa aaggtgggtt tggtgaagta gttgctggaa
     3961 atagacctca agccattgat ttattgaaac agattttgtc agcaaaagga tttgaagttg
     4021 aaaaatacat ttcacctgaa gaagaattga aaggattatc gcaagaagaa aaaattaaaa
     4081 atatagctgg aatatatgct gctaagagac caattaaaaa tttaactaaa
//
LOCUS       DACBYO010000154         4094 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.156, whole genome shotgun sequence.
ACCESSION   DACBYO010000154 DACBYO010000000
VERSION     DACBYO010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.156"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..496
                     /locus_tag="IVD26_002832"
     CDS             <1..496
                     /locus_tag="IVD26_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6080736.1"
                     /translation="STSANGEKIYGTLNAIQVFCEALMMGIVPIIMRKLGVRNTLLLG
                     VTIMCVRIGLCGFASTPLSVSCIKMLHALEVPLFTLPMFRYFTLHFDTKLSATLYMIG
                     FQIAAQIGQVILSTPLGILRDNVGYQPTFKIISLIVLLAGIYAFFILKQDDRDVQGDP
                     FIRG"
     gene            550..1977
                     /locus_tag="IVD26_002833"
     CDS             550..1977
                     /locus_tag="IVD26_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAP6080737.1"
                     /translation="MTKKAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPGDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDRLYMKPVRELEQLRVG
                     SGVETTVNLAGEIIIAQDASFKEALIDVLLTKSKNQEIKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            1990..2860
                     /locus_tag="IVD26_002834"
                     /pseudo
     CDS             1990..2860
                     /locus_tag="IVD26_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185828.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            2955..3950
                     /locus_tag="IVD26_002835"
     CDS             2955..3950
                     /locus_tag="IVD26_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP6080738.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKNN"
BASE COUNT         1454 a          570 c          805 g         1265 t
ORIGIN      
        1 ttcaacatca gctaatggtg aaaaaatata tgggacattg aatgctattc aagtattttg
       61 tgaagcgtta atgatgggaa ttgttccaat cattatgaga aaattagggg ttcgaaatac
      121 tttgttatta ggtgtaacca ttatgtgtgt acgaattgga ttgtgcgggt ttgcctcgac
      181 accattatct gtttcatgca taaaaatgtt gcatgcttta gaagtaccat tatttacatt
      241 accaatgttt cgctatttta cacttcattt tgatacaaag ctatcagcaa ccctctatat
      301 gataggattt cagatagctg ctcaaattgg gcaagtgatt ttatcaacac cattgggaat
      361 attaagagac aacgttggct atcaaccaac atttaaaatt atttctctta ttgtattact
      421 agcaggcata tatgcattct ttattcttaa acaagatgat agagatgttc aaggggatcc
      481 atttattcga ggataatgga aaccaacaga ataaaaaaca attttatcta gaaagtgagc
      541 gaatatatta tgacaaaaaa agctatagaa ttaacaaata cacgttatcg tttgggatat
      601 catgtgtctg caccatcagg atggattaat gatccaaatg gattttgcta ttttgatggg
      661 tattatcatg tgttttatca acatcatcca tatagtgctg aatggggacc aatgcactgg
      721 gcacatgcta gaagtaagga tttagttcat tgggaatctt taccacttgc tttgactcct
      781 ggagatcaag aagatgaagg tggttgtttt tcaggaagcg ctattgaaaa aaatggtgtg
      841 ttgtatctgt tctatacagg acatcactat tatggagaca atgatccaga tcatttttgg
      901 caaaatcaaa acatggcgta tagtacggat ggcattcact ttactaaata tgaaaaaaat
      961 cctgtaatag caaaagcacc agaagataac acacatcatt tcagagatcc aaaagtatgg
     1021 aaacacgatg aaaaatatta catggttttg ggtagtcaag aaaaagatgg attaggtcgt
     1081 gctattgttt atcagtcgtt agatttatta aattgggatt acattggacc aatttctaaa
     1141 gcgaaggaag tacttacaga aggatttatg tgggaatgcc cagacttttt tgaattaaat
     1201 ggaaaatcta ttcttttatt atcccctcag ggaattgaag caaatggaaa agattattta
     1261 aatctatatg aaacaggcta ctttatcggt gattatgatt atgagacagc aaaattcatt
     1321 agaggaaatt tttatgaatt agataaggga cacgatttct atgcaacaca aacaacttta
     1381 tctccagatg gtagacgtat tgttatggcc tggatggata tgtgggaaag ccctatgcct
     1441 gaaaaagtag acggatgggc aggagcatta acgcttcctc gagaattaga gttaattgga
     1501 gatcgtttgt atatgaaacc tgtgagagaa ttagaacaac ttcgagttgg cagcggcgtt
     1561 gaaacgacag ttaatttggc aggagaaata ataatcgctc aagatgcttc attcaaagaa
     1621 gctctaattg atgtactatt gactaaatca aaaaatcaag aaatcaaatt ttcattaaaa
     1681 acaaaagatg aagagttaat caatattttt tattctaagg ataaaaatga atgtacctta
     1741 actcgtaacg gcaaaaatga tccaaggtat ggaaccattc agatgtgtga tagattatca
     1801 cttcgagtgt ttatcgataa aagttcggca gagattttta ttaatgatgg cgagcttgtt
     1861 tttacagagc gttattatac agaaaatcaa ccaagtatgc atttgagtgt tagtgaagaa
     1921 gcttttgtct cgagtacaat ttatcatcta aaaaaagatg caatttctta cgagtaagga
     1981 ggttttatga tgttaattgg tagcatagaa gcaggtggga ctaaatttgt atgtgccgtg
     2041 ggagacgagg attaccgagt acaagaccaa ataatttgtc caacgaccac ccccagggaa
     2101 acattgaaaa aaactgttga ctattttaaa cagtttgata taaatgcatt aggtattgca
     2161 tcatttggtc caatagaaat tcgaaaaaat tcaccaaaat caggatatat tacgtctaca
     2221 ccaaaggtgg gatggcgaaa tgttaatgtg ttaggttatt tacaagatga gctgaatgtt
     2281 ccaatgtctt ggacaacgga tgtgaacgga tcagcttatg gagagtacat catgtccact
     2341 ttatcgaatg aaaaaataaa ttcattagtt tattacaccg ttggtactgg cgttggtggt
     2401 ggagctgttg ttgacggaaa actattagga tcgtttggtc attcagaaat gggccatacg
     2461 tgtaaaacgc catcctgatg atattgattt taaaggaatt tgtccttatc atggtgattg
     2521 tttagaaggc ttagttgcgg gaccaacgtt tgaagcacgt tttggaaaaa agggtgaaga
     2581 cgtttcttta acggatccta tttgggatgt aatggcctat tatctagcac aagctgtgat
     2641 tcaaacaaca ttgattatac gaccggataa aatagtattt ggtggaagcg tagtaaatga
     2701 aaaattgtta gaaaaaattc gtgttaatgt taataaatta ttggatgatt acgtggaaat
     2761 accaccgtta agtaaatata ttacgcgtcc tttaattaaa aataatggat cggcaacact
     2821 aggaaacttt gctttgggct tgaatcaatt acaagaataa aacatagaaa aaatatcgat
     2881 tatcaggtat agtagttcta tagagttctt tttttcgata gttaattatt gcattattta
     2941 ggagagacaa gagaatgcgc ccaaaattag aagatgttgc caaaagagca aatgtatcaa
     3001 aaacaactgt ttcacgtgta ttaaacaatc gtggctattt aagtcaaaaa acgattgata
     3061 atgtttataa ggctatagaa gaactcaatt atcaaccgaa cgttgtagcg cgtcaattat
     3121 ttcaaaagaa aactaacatt gtcgggttac tatttcctac agtagccaat ccttttttta
     3181 gtgaactcgt tgaggcattg gaaaaaaagt tatatgaaat tggttataag gtattaatag
     3241 gcaattcgat gaataataaa gaaaaggaaa caaattattt aaatcagtta ttgtctgatc
     3301 aagtagatgg tttaattgtt ggtacacata accaaggaat tcaggaatat aaatatcaga
     3361 atttaccgat tgttgcaatt gatcgagtga tgaatgaaga tattccagtt gttgaatccg
     3421 ataactacaa tggtggaaaa cttgcaacca agttattaat tgcacaaggt gcaaaaaata
     3481 ttattcatac aaacggtcca attgacttac agactccggc taatcgtcgg agactagcct
     3541 atgaagatac tatgaaagca tatcagttaa ttccacgaac tgtgacatta gatttcaata
     3601 tttcttatgt aaagaaaaaa cagatttttt tccaaatgtt tgaggattat cctaaaatag
     3661 atggtatttt tgcttcaaat gacatcgatg cggccctaat attacaagta gcaaaagaaa
     3721 aggggttaaa tgtaccagct gatttattag tagtcggata tgatggtact ttaatgactc
     3781 ggagtatatt accagatctg acaacagtaa tacaaccaat taatgatata gcagacacag
     3841 ctgttgctat tttgatgaaa cgaataaata aagaagaaac aaaaaaggaa tatattttac
     3901 ctgtcacatt atggatgggg aagacatcag taaagaaaaa gaacaattaa atttataaag
     3961 actatcaatg ataatttcat tattaattcg tgatataaaa aattgttaaa tctcttataa
     4021 tagactatga tacaaaatca tgcttttaat ctgtgtagat gttgccaaat atttgaaaga
     4081 catagaactt gtca
//
LOCUS       DACBYO010000155         4057 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.157, whole genome shotgun sequence.
ACCESSION   DACBYO010000155 DACBYO010000000
VERSION     DACBYO010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4057
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.157"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            86..1435
                     /locus_tag="IVD26_002836"
     CDS             86..1435
                     /locus_tag="IVD26_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP6080739.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="IVD26_002837"
     CDS             complement(1563..2153)
                     /locus_tag="IVD26_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAP6080740.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="IVD26_002838"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="IVD26_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAP6080741.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1169 a          742 c          788 g         1358 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtttattgag
     3781 aggtcgtgaa aaagccgctt agtttcaagt attaagaaat attttgtgaa aatggcttct
     3841 cacatttttg cataaatttg acttaatacc gagaaactgg cttttgaaca ccgtttattg
     3901 agcgtctata aactgacctg agtattagag aaacaaaacg gcaaagtagc tccatatact
     3961 ttgccgtttt gttttgaact aataccgaag agaagctgat caaacaacat ttcttttata
     4021 atatagattt tagacatata tatgatataa aaatagt
//
LOCUS       DACBYO010000156         4010 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.158, whole genome shotgun sequence.
ACCESSION   DACBYO010000156 DACBYO010000000
VERSION     DACBYO010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4010
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.158"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            279..1127
                     /locus_tag="IVD26_002839"
     CDS             279..1127
                     /locus_tag="IVD26_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080742.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(1298..1639)
                     /locus_tag="IVD26_002840"
     CDS             complement(1298..1639)
                     /locus_tag="IVD26_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HAP6080743.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            1725..2432
                     /locus_tag="IVD26_002841"
     CDS             1725..2432
                     /locus_tag="IVD26_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAP6080744.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            2419..2742
                     /locus_tag="IVD26_002842"
     CDS             2419..2742
                     /locus_tag="IVD26_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAP6080745.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(2831..3868)
                     /locus_tag="IVD26_002843"
     CDS             complement(2831..3868)
                     /locus_tag="IVD26_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP6080746.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
BASE COUNT         1183 a          819 c          700 g         1308 t
ORIGIN      
        1 tctttgcgat acatcatacc tcttttatca attggaacaa ttatttattt ctaacaaaat
       61 cacttcattt ttgtcagata aataaaaaac aaaaaaagtt ccatctttaa aacacgctat
      121 tcttttactt tttctcacat tctctaagaa aagaaaagga gaatgaattt ttgacaattc
      181 gagcaaaagt gattatcaaa tatgtaaaat cagctacttt tttcttaaac gtttctttat
      241 actaaatata aataagtgtt tcatgaaagg agaactagat gaataattgg cttgagtatt
      301 ttcctgaaaa cgttttggaa cgcggttaca gctatcatct gcacggtttt gtccgtcatt
      361 tgaactatac aagcaagtac ttgtccgcaa cagtttctgg cacggaagat tataaggtag
      421 tgatcacttg ggatgaaaag accaacatga cttgtgattg tctatatgcc atagaaggaa
      481 aaaaatgcaa acacatggct gctgtcttat tcgcttacga agaacgtcca ataaaaaaat
      541 ccaactactc actttccgaa ctctcgtccc ttgtttcctc cgctagttcc tctcttgtac
      601 gggagctttt aacagagatt cttatagaac atccgcactt tatcgaacgc ttcaaagtta
      661 agatgccatt tcatgcaata aattattcag ataaattaac aactatcatc cataaatacg
      721 atcatattat caagaaaaac aaaaacagga aaacagcgaa gttcatcatg gagatgcgaa
      781 agttcatcca agaagcagtt gaatcgctta ttcagcaaaa tgcctatctt cccgcattcg
      841 aattgatcaa tgaagtgatt gctactctcg aaacattcta ttgggagcct gaggatgaac
      901 gaacccttct tctgatagag gactgttatt atttatggaa agaattatta gcagaagcac
      961 ctcatgcaga aaaaaggcaa atgttctctt ggttcgtctg ccaagtcgat catactgacg
     1021 cctcttattc aaaacgctac tctataaaaa tcctgaaaga agactttcgg gaaaaagaat
     1081 tttctaacca aaagaaaaaa atagataaaa aactaaagaa acggtaaaga aagacgattt
     1141 caatgaaaaa tagcaagtaa acgataacaa ccatcctaaa tccacaagaa atacagcaga
     1201 ccttgcttta aaaacacgaa tcatgcaaag gatgaagtaa agaagactta acgcgtaccc
     1261 aatattagtc atttgactat taggtacgcg ttttgtttta taagtcatga caaatttcct
     1321 tcgttgctgg atagattttc cggcattgtt gatagatttt atgatacttt tctacatttt
     1381 gtaagagagg ttccactgca tctgtatatt ggataaaatt ctgacaacaa ctttcaggtg
     1441 tgtcgaacca ccctaaccct agtgcagcaa tcattgttgc gcctaatgca ggtccttcct
     1501 ccacacttaa acaatagacc gttgcatcga aaatatcagc ttggatttgt agccatgcaa
     1561 gatttttcgc gcctcctccc accgaaacaa tacgtgtaaa tctgcgaccc gctagttctt
     1621 tacgtttcaa tcccaccatt gacaaatgct cattaaaaat ttagaatatt cacaagttta
     1681 acgacaatta tgaaaattta tgtcgtgcta aaggagtttt gttattggat gaaaagttag
     1741 atataaaaac tgcgatcaaa gacacgttac ctaccgtttt cggttatatc ggtattggac
     1801 ttgcatttgg tatcgttggg aaagctgccg gatttcatcc actagtcgtc acgttgatgt
     1861 ccctgctggt ctatgctggt tctgcccaat ttatcacagt cagcatgctt gctagtcaca
     1921 gcccattgct ttccatcgtt ttctcgacct ttctagtcaa ttcccgaatg attctgatga
     1981 gtatgacgat tgctccttat ttcaagaaaa atcggctgct tcaaaatctg ctgattggca
     2041 cattgctgac agatgaaagt ttcgcactgg gaatgaataa attgaactat actggacaaa
     2101 agttaaactt tcgttggatg aatacagcta attggatttc ttatttgacg tgggtgggtt
     2161 cttctcttgt tggcgcactt ttagggaatt ttattactga tccgaaaaag tttggtttgg
     2221 atttcgccat cgtcgctatg tttatcgggt tactttatct tcaagtcatt tctgatagaa
     2281 acacctctaa acgattacag ttgatcctga ttggtctcac tttgattctg gtatatgtcg
     2341 gactgatttt tatcccaagc aacttagtga ttgtagttgt aacactgatt gggtgcggat
     2401 tgggggtgtg gatcaaacat gccttctttt gagtttacat tgctgactat tttaggttgt
     2461 actttagcaa cttggctttc tagggtccta ccatttgtct tactgaaaaa attcgattta
     2521 ccgcaaccgt tgcttgagta tttaagtttt gtcccgatcg tcattatgtc tgctttatgg
     2581 ttcagcagtc tatttaccca aaatatcgga catctgccgc agatcaatct cgaaaatgct
     2641 ttggcttcag ttcctacact tttagctgct attctttcaa aaagcttatt ggtgatcgtc
     2701 ttggcaggaa ttctttccct ttcgttgatt cgcttattat aaataaaaaa acaagagctt
     2761 atggcaaatt actgtcatgc gctcttgttt ttatcaaagt caaataagaa aaaaatcggc
     2821 gtattcttgc ttatccgttg aacggaccac taacaacgac ttttcctaac atatgtcctg
     2881 tttctacgtc tttggttgct tgtttcaagt tcttcgcatt catcccatct gaatagacct
     2941 tgctcaatgt actgcggata atcccttcat ttgctaaagc agcaatgtgc gctaaagctt
     3001 ctccttgcgt ttcgatttca tagttatagt ctgttttagc gaacatatac tcccagtcga
     3061 agctgataga ttggtttttc caaacaccta tatctaacgg ctctttgatc cctacgatcg
     3121 ttcccacatg tccaaatggt cggacaaggt gcttgatttg atcaaagtag cgggtaatat
     3181 cgaataatac agcgacatac tctacttgat cgattcctaa ttcacgaaaa cttttactta
     3241 agtcgtgatg ataatcgatt ggatagtcta cacctgtttt tttcagccat tcaaaattct
     3301 tcggacttgc agtcgcgtag acttctaggc cagcccaatg cgctagttga ttcaaaatcg
     3361 aaccgacgcc cccggatccg ttgatcacta agattttttt cccgcgattg gcattttctt
     3421 ctggagttag accaaatttt tcaaataaca attcataagc ggtcaatgag gtcaacggca
     3481 aggctgcagc ttcttcatct gaaagatttt ttggtgcaag agcgacaata cgttcgtcaa
     3541 ctagttggta ttcttgattg cttcctgctc ttgttgttgt acctgcgtaa aaaacgcgat
     3601 cgccgacaga aaatttttgc acttcgtcac ctacagcaac aactttcccg actccatcaa
     3661 aacctaagat acgtaaagca tttcttatcc cgttatcttg gcgaagtttc gtatcgacag
     3721 gattaacaga tactgcgttg acttttacca gaagatcccg tgaactgggt acaggtatct
     3781 gttctttttc atcaataaag ctttttggat catcgatcgg caacccttca taaaaaccga
     3841 ctaccttcat taattccttt tctgacatac gaattcctcc ttagcttcat caagttggag
     3901 catccataca gtgttcattt caatatatat agtatgctat ttgttccacc ttttttattc
     3961 atcataatta ttctcttact taaagtaaac tatttgcact tttttggtta
//
LOCUS       DACBYO010000157         3878 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.159, whole genome shotgun sequence.
ACCESSION   DACBYO010000157 DACBYO010000000
VERSION     DACBYO010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3878
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.159"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..679
                     /locus_tag="IVD26_002844"
     CDS             <1..679
                     /locus_tag="IVD26_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080747.1"
                     /translation="VVYGVAYYLLSEPKQIAASNIFTAVMTLMCVMCFSIFSYLLVQF
                     IRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIKNFLTTIDQFINGYMYL
                     FEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVDFGKYEELIHTDIVHTS
                     IHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGIGKLRLDGSNIQQNKPY
                     VLGKVVI"
     gene            723..992
                     /locus_tag="IVD26_002845"
     CDS             723..992
                     /locus_tag="IVD26_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080748.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            1224..1520
                     /locus_tag="IVD26_002846"
     CDS             1224..1520
                     /locus_tag="IVD26_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080749.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            1522..1944
                     /locus_tag="IVD26_002847"
     CDS             1522..1944
                     /locus_tag="IVD26_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080750.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            1963..3555
                     /locus_tag="IVD26_002848"
     CDS             1963..3555
                     /locus_tag="IVD26_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080751.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            3576..>3878
                     /locus_tag="IVD26_002849"
     CDS             3576..>3878
                     /locus_tag="IVD26_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080752.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVNGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKS"
BASE COUNT         1517 a          555 c          766 g         1040 t
ORIGIN      
        1 ggtggtctat ggggtggcct attacttgtt aagtgagcca aaacagatcg cggcgtcaaa
       61 tattttcacg gcagtaatga cattaatgtg tgtcatgtgc ttttctattt ttagttactt
      121 actcgtccaa tttatcaggc aaaatttaac aatgagtaaa cttttcaaaa gtttattgga
      181 cttacttatc ttaggcagta tgttaacgac tctaacagat cggttcgaac aatctgaaaa
      241 aacggtagag gggataaaga acttcttaac gacgattgat caatttataa atggatatat
      301 gtatttgttt gaagtaggct ttattctcac tttgtttggt tgtgtattta taaaactcat
      361 taaaagatca atcgaaaaag aaatggttat tgatctaatt ccgacgctga gcggctatga
      421 gtattacgtt gattttggaa agtatgagga gttgatccat acggatatcg ttcacacgag
      481 tatccatgaa gtaaccgtta agggcatcag atctacttta aaagatggac aggagacgaa
      541 aacaatcgac cgaagaaaag aggtctacaa tttttataaa gttgaagcaa gtctacgata
      601 tggcattggg aaattgaggt tagatgggag taatattcaa caaaacaaac catatgtttt
      661 aggaaaagtg gtgatttaga acttcctatg aaagatgaat aaataaggag aatcttttga
      721 aaatgattct tctttacaga attgtgctta tagttggcac ggagttaaaa atcttaaaga
      781 aggagcagtt attcaaagtg aaagaacatc ataatcagtt actatgtatt aaaacgggta
      841 cgatgaacat tcaataccga acagaatatt tagaattaac gaatcaaact gattttttgt
      901 cgattcgaga gcaacataag caagaaaaat taatggctac ttatagccaa ttgattgatg
      961 agtgggaaca attcaaggaa tctaaaacat aaaattccat ttaaacacct tattttttaa
     1021 agagcataag gaaacgtgac cccactttta aaaaaagtgg ttggataggc tgtgcctatc
     1081 acgtttctga aaaaaataaa tgaccccaaa ataccaatat ataggatagt acaaggatag
     1141 caaaggatag taaaaggata gaggtaggat agcgaaaagg ataggatcct tttcactatc
     1201 ctatattata ttggaggata tttatgaatg ttaaaattag agatttagat ccaaaattca
     1261 tttctgaaat tgatcgaaga tgcgttgaac taagtaatcg tacaggaaat aaatggagtc
     1321 gtaatgatta tttaaagcta ctcgttgaaa atgattttga tcgtcctttg atggaataca
     1381 aacaagaaaa gtttgaccag ttattagaaa agttttcaga aattcaaagt tataacacaa
     1441 agatattaga agaatatgtt agccaaaata atcgtattat agaaatcttg attgagcaaa
     1501 atagaggaag tgaactttga tatggcaaag gttatagaca aacacattta ctttcaccaa
     1561 acacatatcg atgtattgga tgaaactatt tctactcatg cagaggttaa aaactatagt
     1621 gaagctgttc gctttttatg tatgaactat gatccagaag tggagaaaaa agtaaattcc
     1681 aatcaagcaa agttgaatgg aatgagtaaa gaaatttcta ttttaaccga aatggtttca
     1741 gaatttgcgg atcttcattt gaaagataca ggaatattaa ttggtaaaaa ttcaactgtt
     1801 tatcaagaag caaaagaacg agtggaagga aaaattaaat ccaatcaaac aaaaaaatat
     1861 tcccctcagt tgaagaaacc tgtgaatgaa tctgttcatg ccagagtaga tccatttgat
     1921 ccaacgaaga ttctaaaaag ataaaaatga aggaggataa taatgactca atcgccttca
     1981 gttattctca cttgtcaatt tactttgccg aataaaaagt cattttctac ttatattgac
     2041 tatattacaa gggaacaggc tcttgaagaa aaggaacgac gtacgcccga agaagaacag
     2101 gaacttcaac gaatcaagaa tgctttagag gagttttata ttcctgaagg agaaactttt
     2161 tcggagagta agacgggtaa agaattcagt gaaacgtcga atgaagctca atcgttgatg
     2221 gaacatggaa tcaattttga caagttagag gaacaagatt ttaccaatta tctttcttat
     2281 atgacacgtc actatgcgtt agaacaaaag aaagaactga cgcaaagtga acaaaaagaa
     2341 taccaacgct tgaaccaagc aatgaaaaaa tatcaaacag aaccccataa aaaagcttca
     2401 ggaaatcttc ctggagtttt ttctatagct tcagacgaag tgaaaggaag tgatctgaag
     2461 gagattaagc aaatcttcca aagaggacaa caaaaaggct caatcattta tcaagatgtt
     2521 gtttctcatg ataattcgta tcttgaaaaa ataggattgt acgatcccaa aacagatact
     2581 ttagatgaag aagggttaaa agcagctgga agaaaaatga tggagacatt attcgagaaa
     2641 gaacaattga atgaaacagg ttactggatg gcaacgattc accgtaacac taaacatatc
     2701 catattcatt ttgcagttgt tgaaaaagaa aatacgcgta aaccttacac ggaggttgaa
     2761 aatggtgtga gttatatcgt accgaaaggt aagagaagac aagcaacatt agacgcaatg
     2821 aagaccaatt atgtacatga gttagaacgt ttttcttatg aaaaggatcg aatgattggt
     2881 atggagaaac gaaatttatt gacgcggaaa agtgatttgc gtaacacctt aacaaaagtg
     2941 gtaaaagagc cagcgcgtta cgatcgacac gcgatgaact tattaaatga agtatataaa
     3001 accctacctg acaaacgttc ggaatggaat tacggggatg aaaaacgaac caaactttca
     3061 ccatacacaa gagagaaact cgatgagtta accaaatatg ttttaacaaa agaacctgaa
     3121 tatcaagaat atatacagat ttcaaaagca ttgaaagaag aagcaaaaag tctttatggg
     3181 gaaagcaaga gagaatcaaa ggatgcagag aaaaatgctc tctttgattt aaaaaagcgc
     3241 acaggaaatg ccatcctaac agagctgaag agacaggata gtcaaataaa accattaata
     3301 gaaagtgttg atcagatgca atctatttac aatgaacgat cctttcgaac gcttaaacaa
     3361 ttgccaacga atgaatacaa atatagttac gaagaattca tgaagcgcag gaaacaattc
     3421 caacaaagag ttgtcacgca gcggagtttg cgtcaattaa atcgaacgat taatgcccat
     3481 gaagaaaaat accacgcaag taaagcatac gaagagcaac aacgaagaat tcaaatggaa
     3541 caagaaagac agtaaagaca gtaggaggaa tagcaatgaa acaatattta gatcaatgga
     3601 aagttataga aggatcatta agagaagaac gaatcgaaca acttcctgat tgtttagaaa
     3661 aagagcattt gttccagata agagaaatgt tgagaaacga acagtttgat ccaaatcaat
     3721 ttttagtcgt tgagtaccca gctactggtg tgtattgttg taatcatgtg aatggtgaaa
     3781 aatattttat cattcaagaa tatgagggca agttagcacc ttattatact acttgggaaa
     3841 tgaatgaaga gggaatcaat aactttccat gtaaaagc
//
LOCUS       DACBYO010000158         3854 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.160, whole genome shotgun sequence.
ACCESSION   DACBYO010000158 DACBYO010000000
VERSION     DACBYO010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.160"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..321
                     /gene="tnpB"
                     /locus_tag="IVD26_002850"
     CDS             <1..321
                     /gene="tnpB"
                     /locus_tag="IVD26_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAP6080753.1"
                     /translation="ICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKI
                     IKVDKWFPSSQICSNCGHKDGKKSLEIREWTCPICHTHHDRDINASINILTEGLRLHS
                     MGLA"
     gene            complement(483..935)
                     /locus_tag="IVD26_002851"
                     /pseudo
     CDS             complement(483..935)
                     /locus_tag="IVD26_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
     gene            1384..1998
                     /locus_tag="IVD26_002852"
     CDS             1384..1998
                     /locus_tag="IVD26_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6080754.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            complement(2022..2372)
                     /locus_tag="IVD26_002853"
     CDS             complement(2022..2372)
                     /locus_tag="IVD26_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP6080755.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(2366..2629)
                     /locus_tag="IVD26_002854"
     CDS             complement(2366..2629)
                     /locus_tag="IVD26_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HAP6080756.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            complement(2747..2926)
                     /locus_tag="IVD26_002855"
     CDS             complement(2747..2926)
                     /locus_tag="IVD26_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080757.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQKLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            complement(3371..3808)
                     /locus_tag="IVD26_002856"
     CDS             complement(3371..3808)
                     /locus_tag="IVD26_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080758.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
BASE COUNT         1169 a          737 c          632 g         1316 t
ORIGIN      
        1 atctgtattg aagacttaaa cacaaaaggc atgttgcgta atcataaact agcaaaaagt
       61 atttcggatg tttcttggtc tagttttgtg tctaaattac aatacaaggc tgactggtac
      121 ggtcggaaaa tcatcaaagt agataagtgg tttccatcta gccaaatctg ttcgaattgt
      181 ggacataaag acggcaagaa atctctcgaa attcgagaat ggacttgccc tatttgtcat
      241 actcatcatg accgagatat caacgctagt atcaatatcc tgaccgaagg tctaaggcta
      301 cactctatgg gattggctta gatcaaataa acaagaaccg taggaactac ggggatagct
      361 tggtaaataa gaggcacctc tgttagtaaa gtaatacgct atcaagtatg ctctcttccc
      421 aagaagctcc cacttcaagc gtaagaaacc gttaggttta gctaagtggt gagtagttca
      481 ctatgttcct ggatcatttg agcaagtttc tgcctgcgct gacttcttgt tccttcagtc
      541 gtaaaaagat tcagtgatct ggtcactttt aagatcgatt catcgatcga atagatcaat
      601 aaatcttcgt ctgctacata ccttctgaaa atattgttta cctgcatgtt tcgcttaata
      661 tagagattca tgcgtggtgg aacgacatgt aacgttttag gaaaaggctg tggtagatcc
      721 cgtggtctgc tgacattaga aataccgtac ttcttctttg cagctggtga agaagctaaa
      781 atcaaccctg atccagtgtt gtcagcacga ctcataacaa caagttctgt tgttaatgga
      841 tctaagtttc tttctataca ttcgacactt gcgtaaaagc ttttcatatc gattaaaaag
      901 taatcattta ctggctcttt tgaataatcc atcataaata acactccatt ctttcacatt
      961 atacaaacat atgttcgata ttgtaaagaa gaaatagcta aatacataaa aaagaagcat
     1021 aggtatgcta tcaccctgct tcttcttttg atttgtatga tcaatttatt ctatcacttt
     1081 actaattaat ttgaaaatct aataaaaact ctcactctaa aagagtgaga gaccgcaaat
     1141 tagagtacgg acttttttgg agttccgttc tttaatatta acaaatgaat aaaatcctta
     1201 caacatttga gaataagtta tcagtagaca cttacaaaaa attctcatac tatttcctcc
     1261 atcattagtt tttgtctata taaggtatac cctaactaga cacgaccgcg acattgaaaa
     1321 atctggtttt ctcgtgtatg attagggtgt tttttaaata gttgcagaaa gtaggtaaaa
     1381 attttgagag ttgcatacat acgtgtctca tccatcgatc aaaatgaaca acggcagatt
     1441 gaagaaatga aaaaattcgg tgcagagaga attttcattg agaaacaatc tggcgcaacg
     1501 attactcatc gacttgtttt tcaagaagca ctggatttcg tccgagatca agatattttt
     1561 attgtggaag ctattgatcg acttggaaga aattacgacg agatcatcgc ttcagtcaat
     1621 tacttgaaga agaaaaatgt gcagctgatc atcacaagtc taccgatcat ggccgaagca
     1681 attggcaatc ctctcctgga taaattcatt aaagatttga tcattcaaat tttggccatg
     1741 atcgctgaac aagaacgtac cgaatctaaa cgacgtcagg cacaaggcat taagattgca
     1801 aaagcgaacg gtgtttataa aggacgtcct aagctataca gtgccaatgc aaaagatccc
     1861 caacgtcgtc ttgtttataa aaacatcgtt gaggatctaa aaaaaggtgt tgcgatcgct
     1921 aagattgcaa aagactacaa tgttacgaga caaaccgtat atagaataaa aaaagacagc
     1981 atggtcaatc acgaatagtt gatcatgctg ctgtttctat tttatttgct tactttttga
     2041 aaaactgttc taactttcat caataactcc tcaactaaac tatcatgcgc tttttccaaa
     2101 aaaatacact ctctggcttc ataatcaatt gtcgttagtt gatctaataa tacttttcct
     2161 gttgtcttca tttcatattc tgagtttata tttacatata gcggatagtt tctagttgta
     2221 ctagaaattg gagcaactgt aacaacgtta ctataatccg caataatatc atgacttaaa
     2281 acaatataag gtcttttacc tgtctgttcg tgtccagatc gaggtgctgt attcaataat
     2341 agaatatcgc cttgtctagg ttttctcacc atttttcatt acctactgct tcacctaaat
     2401 tttgaatcgt cacatgattt ctttcatcag tgtaattttc aaataactgt tcaattgtta
     2461 attcattttc tatattagcc gcttcgataa ttagccgctt ctgaccgttt acttcttctt
     2521 gtattatctt cactttgtct tctgtatgaa ttccaagata ttccataata tactttggca
     2581 atctaaggcc attactattt ccccattttt ttataggtaa catttccata gtagacacct
     2641 ctttctgtat atacatagta taacatacat aagaaaaaac gtatatactt aattatcctt
     2701 ttctattaag tgctatcact tttgtttctt caaatgaaaa gtgacgtcac tttttgagtg
     2761 ctggtacatc aaatcctgct ttttcttgcg cgatcaatag atctaacgca atacacataa
     2821 tcttagattc actttttccg tacttctgct ttagtttctg caattctttt tgtctctttt
     2881 catccaacgt aacgggtaac cgtttatttc ctattgcaat tggcattagt actctctcct
     2941 ttcatcgaaa taaccctatg aaaaatatgg ctgcaatcaa cttgaatatt agactcacaa
     3001 gggctaacac aaagcgccaa aagatcaaac aaaacaccag tattaccaaa aatactacga
     3061 agtttaaatg cacagctgca ctatgtcgca taattatttc gccaacaaac agtactaaca
     3121 ataagggaat aatcttgttc aaatggatca ccttctttct cttgagttat cgggctttgc
     3181 ccgtttattt cgcatcacct aagcggcggg ggcggttgga gcgattggtg cgaaataaga
     3241 accattccct tagttactag gctttttttg tccttatttc acacgttctc acttttcggt
     3301 ataaatgatt attgaccttt ttttctttca aatcgttgat atggaatccg ttgttagttg
     3361 ataaatcacc ttattcattt tcgttgtctt cctttttcat ggtgtaatat gcgccatact
     3421 tattgatatt ttcaaaataa tctaaccatt cacttgaaac agtcttggct tttttcgttt
     3481 cgataaattt cgcatacgtt agttctaaag cttggtattc agaaggtttg attgtgcttg
     3541 gtttgacgcc tacttccaag catagtaagg cttggaaaaa ccattttgca ttttgctttt
     3601 tcagttcttc cagtgttcga tagtacgtcg caatgagatt catttcgaca cctgattcaa
     3661 tcatttcttc cacagctacc gacaattttt ctttataatg tttctttgga acacgtgttt
     3721 cgttgtatag gaacgtcata tcctccattt tttgtgccat tttatccaaa ggtaatttga
     3781 caaattcgtc atagtaattt tgagccatat ttttttctcc tttttagttc tctaatttgg
     3841 ttaaccaata ttcg
//
LOCUS       DACBYO010000159         3849 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.161, whole genome shotgun sequence.
ACCESSION   DACBYO010000159 DACBYO010000000
VERSION     DACBYO010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.161"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            3..1631
                     /locus_tag="IVD26_002857"
     CDS             3..1631
                     /locus_tag="IVD26_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080759.1"
                     /translation="MNKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRIKG
                     LSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNLCT
                     TLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFYAY
                     QIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFIAI
                     FKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNNDL
                     TTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAKLL
                     QFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFNQK
                     IISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNLPY
                     KTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGVAD
                     IKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            1806..2639
                     /gene="msrA"
                     /locus_tag="IVD26_002858"
     CDS             1806..2639
                     /gene="msrA"
                     /locus_tag="IVD26_002858"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP6080760.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            2719..3708
                     /locus_tag="IVD26_002859"
     CDS             2719..3708
                     /locus_tag="IVD26_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAP6080761.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1352 a          606 c          707 g         1184 t
ORIGIN      
        1 aaataaataa aaaagtagta atattgagtg gattaattat agttagtagt atatattctt
       61 tcatcttttt caaaaataca cagagtattt ataccactgg agatctttct tttcacttat
      121 ctcgaatcaa ggggttatcg actattttta ccagtccgat taattatgag acattcaatt
      181 atactggata tggtgtaaat tatttttatc cctttctgac tttttttcca gctgtaatgt
      241 tatattggat gacaaaaaat ttgattgtaa gctatattat ttacgtttgg ttattgaact
      301 tgtgtacaac actcgtagct tatcattatg gcgagcggtt tttaaaacaa aaaaaagcgg
      361 catttttatt tagttgtctc tatattttct ctgcttatcg gacagtagac atctactatc
      421 gttccgcaat tgccgaagct atcgcaataa cacttgttat ccctgtatta ttttatgctt
      481 atcaaatcat ctctggaaaa gaagaaaagt atccgtctgt aaagctagca ttgagtatga
      541 gtttgctagt gtacagccat gtactatcaa cattaatgag tacagcatta attatcattt
      601 ttatttttat tcgtttggtt tctaaaggtt tcaagaatgc agattttatt gctatattta
      661 aaaaattatt tagtgcggca ggaatgacat tggttctgac gagtgctttt tggtatccga
      721 tgtttgaaca aatgctctac caaaaaatca acaaacctag cgtgacaaat ttatatgctc
      781 atgcatctaa tgtgttcgat agtctgactg aagctatgaa caacgactta actacttact
      841 caatgggact agttggtctg ttatctttat gtattcccct gattttattt aaaaaattaa
      901 caaacataga aaaaaagatt tattatggta cgtgtttgac ttggctagct acaactagtt
      961 tggtgccatg gtatcttctg caaaatacgc cagccaaatt gttacaattt ccttggcgga
     1021 tcttaagctt gcaaataata ttctcttctc tgatattaac gatgatattt ttcaaaaata
     1081 gaagatacaa taagacaaga gaactatttt atttatttat gactgttttg ttattaatca
     1141 ctttaactgt ttctagtaaa aaaaatttca atcaaaaaat aatttctcag ccgggacata
     1201 ttgttgtaaa caaagaaaca gtagaggcgt ataccactaa aggaatggat tattttttat
     1261 atgattattc tcctatcgct tcattggaga ataaggagca tataataaaa cacgaagcaa
     1321 agattggcag tcaatgggta aaccttcctt ataaaacaac tggtagttct atcatatata
     1381 gagtaactaa tgagaagagc caagtaatca cacttcctgt atatgcttat ttaggaacga
     1441 atgtagaaat aaatcatcaa cctgtaaagg agcaggtgaa tgctaatgga ttggtacaaa
     1501 taagcggagt caaaggagtt gctgatatta aagtaagcac aagttataca gtaacgacta
     1561 ttatttctta tcttgttaca ttaactgcat atttatgttt attttttaaa atagttttcc
     1621 ataaaaggta aattaacttt tcatttataa aataaattga ttaaaaagga gaatctgtcg
     1681 ataaggattc tctctttttt atacgaaaaa tctgtagggg gatgaagtaa tcgcttattt
     1741 cctcacttta tgataaatta cagctaaagt cactagcttg tcttcttcgg aaaggaggag
     1801 aatctatgga tgaggaacaa atattcattc aaacacttta taatctgatt ttgaatccga
     1861 atacacgaga ttgggaacga aaagtattga ttcagacaaa gaatgacata agagaaaata
     1921 tatccgttaa agaacagtta tcaaaactag aagcaacact acgtccatta gctatccgaa
     1981 tgaatctgac gcctgatgta atggactttt atttattgat tacggaagga tttgataagg
     2041 agcaaaaata tgacttttcc aagcatgcca tgcaagatgc tgactatcaa gaacgtgcag
     2101 tatttgcagg gggatgtttc tggtgtatgg tcgagccgtt tgaatcgaaa aaagggatcc
     2161 tatctgtttt gtcaggatac acgggcggac atgttgaaaa accaaattat gatcaagtaa
     2221 gtggtggtta cacaggtcat gtggaagctg tggagatcat ttatgacaca agagaaataa
     2281 gttatagcga gttgctgaca atctattggc aaattactga tcccacagat acatttggac
     2341 aatttcaaga tagagggaag caatatcgtc cagtgatttt ttatcaaggc gaacgacaaa
     2401 aagaattagc ggaacaatca aaacagaaac tagacagttc aggaactttc caccaaccaa
     2461 tcgtcacaaa aatcgaacca gccggtacgt tttggccagc agaaaactat catcagcaat
     2521 tttacaaaaa acaaccgaaa cgttataaaa aaatccagca agcacgtaat caatttctga
     2581 tctatcaacg agtaaaaaac aaatggcaaa aaaatatacg aaaaaatcat tttgattaac
     2641 tccttttctt taaaatgtag taaactaaaa atagaaaaaa gaaagcgttt taaaaagatt
     2701 tgatgaggag gagaaaaatt gtatattgca gatagtgcac gttatgaaaa aatggaatat
     2761 cgtaaatccg gtcattcagg tttgaaatta ccgattttat ctctcggatt atggcaaaat
     2821 tttggtgatt atgatcctat ccataatcaa agagagattt taagaggcgc attcgacatg
     2881 ggaattaccc atttcgacct tgcgaataat tatggaggcc ctgctggagc tgcagagaaa
     2941 aactttgggc gtatttttag agaagatttt caagcctacc gtgatgaact gattatttct
     3001 agcaaagcag gttatcatat gtgggaaggg ccatatgggg aatggggctc tcgtaaatcc
     3061 atcatttcaa gttgtgacca aagtctccaa agaatggggc tagattatgt tgacatcttc
     3121 tatcatcatc gcccagaccc tgatacacct ttggaagaaa cagcagaagc tttgatgcaa
     3181 cttgtaagac aaggaaaagc attatatatt ggtatatcca actataatgg agaagataca
     3241 aaaaaaatga ctgaaatttt aaaaagaaag gaagcaccgt tcattattca tcagatgcgc
     3301 tacaatatgt tttctcgtgc actactagaa gacgatctat ctccagtatt agaagaagaa
     3361 gggctagggg caatcacgtt cagtccgctt gctcaagggt tgctgacaaa tcgttatcta
     3421 catggtattc ctgaagattc tagagcacat cgtaaggaaa taccattcct ttcagaagaa
     3481 caagttggat caactctgga aaaaatcaaa gcactgcaaa caatcgccgt atcacgagga
     3541 caatcattag cgcaaatggc ccttgcatgg aatttgcgac aaaaatctgt tacaagtgta
     3601 ctggtcggag caagtcggtt aagtcagtta caagaaagtg ttcgaatgat ggataattta
     3661 gatttctcac cagaagaaga attgagaatc gaccaaattc tagaatagaa acgatgtaat
     3721 caaacttttt atccatatat taaaaaaaac aaaagatgac atcaagaatc gaatgaagat
     3781 cgtctgttat tgaacatcat attttttgtc gttcaaaata aaaatgatcg aaggctagga
     3841 gtgaatttt
//
LOCUS       DACBYO010000160         3849 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.162, whole genome shotgun sequence.
ACCESSION   DACBYO010000160 DACBYO010000000
VERSION     DACBYO010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.162"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(1..1155)
                     /locus_tag="IVD26_002860"
     CDS             complement(1..1155)
                     /locus_tag="IVD26_002860"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAP6080762.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            1340..3781
                     /locus_tag="IVD26_002861"
     CDS             1340..3781
                     /locus_tag="IVD26_002861"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAP6080763.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         1231 a          721 c          840 g         1057 t
ORIGIN      
        1 ttatattttg tagtaacgaa tatcattttc gatctttgta atcgaaaaag gtacatctga
       61 agtatattct gcacattctc cgtgttcagg aagcgtctca ctgaaaatcg tttcatattc
      121 gtcaacagtg atccgtgttc gagaatctag catctcttga tgagattgtg cgaagagata
      181 ttcttgatag ttttcttcca gataacctgt aaaaaattca cttactgcac cagaaccgta
      241 gctgaataga ccgatgcgat ctcctggctg tagtgatttc gaattttcca gtagagaagt
      301 tagccccagg tataatgaac cagtgtaaag attaccgatt cgtcggctgt aacggatgct
      361 ttcttcatag cgagccataa gacgttcctg attttcttcg tctgtttggt ctaatacgct
      421 ttgcaatgcc ttttttccca tcttagtata cggaatatgg aaagcaatcg cctgataatc
      481 ttcgagtcct cgacccgaca attctttatg tcgattccaa actttttgga atgattcgat
      541 atacgtagaa ttagataaag gaccatcaac aacaggaaat tcgctataat ctggacgcca
      601 gaaatcatag atatcttctg tcagaaatac gctgtcgtct tcaatcgata aaatacgcgg
      661 gttttgagtg atcatcatcg caacagcacc gacaccttgc gtcacttcac caccgcttgc
      721 caagctgtaa cgagcaatat cacttgctat gactagtact tttcgttctg gatgattttt
      781 gacatattct ttcgccatgt gcaaagctgc ggtgccaccg tagcaagcct cttttacttc
      841 aaaagaacga gcaaaagatt ggattttcag taaatggtgg ataattaccg cactcgcttt
      901 tgaatgatca atcccggatt ctgttccgac gatgaccatg tcgattagct cacggtcttt
      961 ttctgttacg attttgctgg cagcatttgc tcctagtgta atgatgtctt catttgcacg
     1021 attgactgcc atttggtctt gaccaatccc tatatggtat tttgcaggat catccccacg
     1081 gctttctgcc aactctgtca tatctaaata taaattagga ataaaaaagg aaagacgatc
     1141 aatccctatt ttcatttcaa cacctcttta cttatgataa aaaacttact ttactaaggt
     1201 atcataaaaa gattaaaaga aatataaaaa agagaatatt taaggattgt taaaatttaa
     1261 tcttagaaaa aaataactgg aacaagagct atttgttttt acagcaaaga atggtatatt
     1321 tttgtaggag gtggcttact tgaaagaagt cgttatgata gatgctgcaa gaacgccgat
     1381 aggaaagtat cgcggaagtt taagtccatt tactgcagtt gaattaggca cacttgtgac
     1441 taaaggatta ttagataaaa caaaactgaa aaaagataaa atcgatcaag taatatttgg
     1501 aaatgtcctg caagctggta atggtcaaaa tgttgccaga cagattgctt tgaacagcgg
     1561 tctccctgta gatgtcccag caatgacgat caatgaagtt tgcggatctg gtatgaaagc
     1621 agtgatctta gcacgccagc tgatccaatt aggtgaagca gaacttgtga tagccggcgg
     1681 aacagagagt atgtctcaag cacctatgct gaaacagtat cagtcagaaa caaatgaata
     1741 tggtgaacca atttccagta tggtcaacga cggattgact gacgcatttt caaatgcaca
     1801 tatgggatta accgcagaga atgttgcaac acaattttct gtgagcagag aagagcagga
     1861 tcgctatgcc ttgtcgtccc agttgaaagc agcacatgct gtcgaagccg gtgtattttc
     1921 tgaggagatc atcccagtca agatttctga tgaagacgtg ttatctgagg atgaagcagt
     1981 tcgtggaaat agtacattgg aaaaactggg cacgttacgt acagtattct cagaagaagg
     2041 aactgtaaca gcaggaaatg cttccccgtt gaatgacggt gcctctgtgg tgatccttgc
     2101 atccaaagaa tacgcagaaa ataataatct gccttattta gcaaccatca aagaagtagc
     2161 ggaggtcggt attgacccaa gtatcatggg aatcgctcca atcaaagcca ttcaaaaatt
     2221 gacagataga tcaggaatga atttatcaac aatcgatctt tttgagatca atgaagcatt
     2281 tgcagcttct tctatcgtag ttagccaaga actgcagtta gatgaagaaa aggtcaatat
     2341 atatggagga gcaatcgcat taggccatcc aattggtgca agcggtgcac gtatcttgac
     2401 tacattagct tacggattgc ttcgtgaaca gaagagatac ggtattgctt cattatgtat
     2461 tggtggaggt ttaggcttgg cagtcttgtt agaagcgaat atggagcaaa cacataagga
     2521 tgtgcaaaaa aaaaagtttt atcagcttac gccatctgaa cggcgcagtc aattaataga
     2581 aaaaaatgta ttgacacaag aaactgcgtt gatttttcag gaacaaacac tttctgaaga
     2641 gctctccgat cacatgatcg aaaaccaagt gagtgaagtg gaaatcccaa tggggatcgc
     2701 gcagaatttt caaatcaatg gcaagaaaaa atggattccg atggcaacag aggaaccatc
     2761 tgtcattgca gctgcaagta atggtgcaaa aatctgtgga aatatctgcg cagaaacacc
     2821 tcagcggctg atgcgagggc aaatcgttct atcaggaaaa tcggagtatc aagcagtgat
     2881 caatgcagtt aatcatcgaa aagaagagct gattctttgt gcaaatgaaa gttatccttc
     2941 aatcgtgaaa cgcgggggcg gtgttcaaga tatctctact cgggaattca tggggagttt
     3001 ccatgcatac ttatctattg attttttagt ggatgtaaaa gatgcaatgg gcgctaacat
     3061 gatcaactcg attcttgaga gtgtggcaaa caagttacgg gagtggttcc ctgaagaaga
     3121 gattctattc agtattttaa gtaattttgc tacagaatca ttggcttctg cctgttgtga
     3181 aatcccattc gaacgcttag ggagaaacaa agaaatcggt gaacaaattg ccaaaaaaat
     3241 ccaacaggca ggggaatatg cgaagcttga cccttaccgt gcagcaacgc acaacaaagg
     3301 gatcatgaat ggtatagaag ctgtagtggc agctacagga aatgatacac gtgcggttag
     3361 cgcttcgatc cacgcctacg cggcaagaaa tggattatac caaggattaa cagactggca
     3421 gatcaaaggg gataaactag ttggaaaact aacggtgcct ttggctgttg ccacagtagg
     3481 cggagcttcc aatatcctgc caaaagcaaa agcatcttta gctatgttag atattgattc
     3541 agccaaggaa ctagcacaag taattgctgc agtagggtta gctcaaaacc tggctgcttt
     3601 gcgtgcatta gttacagaag gaatccaaaa aggccacatg ggacttcaag ctcgttcatt
     3661 agcgatctca attggggcta ttggtgagga aatcgagcaa gttgcgaaaa aattacgtga
     3721 agcagaaaag atgaaccagc agacagctat acaaatattg gaaaaaatcc gggaaaaata
     3781 aaaaagcaat atctttagaa gaataaagca agatttacag ttattttatt tactgcagat
     3841 cttgctttt
//
LOCUS       DACBYO010000161         3754 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.163, whole genome shotgun sequence.
ACCESSION   DACBYO010000161 DACBYO010000000
VERSION     DACBYO010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.163"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            288..2234
                     /locus_tag="IVD26_002862"
     CDS             288..2234
                     /locus_tag="IVD26_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP6080764.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
     gene            2237..2692
                     /locus_tag="IVD26_002863"
     CDS             2237..2692
                     /locus_tag="IVD26_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP6080765.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            2706..>3754
                     /locus_tag="IVD26_002864"
     CDS             2706..>3754
                     /locus_tag="IVD26_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAP6080766.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIP"
BASE COUNT         1243 a          524 c          709 g         1278 t
ORIGIN      
        1 tataataaaa aaatacgaat tttagtgacg ccattatatt gtttttattt ttcaattgta
       61 atatttcata ttacttccat aataaggagt attttctatt ggaatatctt agctctttta
      121 aggatttctc cttttttgtt tctcattttt taagattatt tggatttcct ttacaacaaa
      181 cttccacaag tattattgac atagatgtaa ttgagggaag ggggttccag tgctagaata
      241 aataatgaaa agaggtaaca aatgctagcg ttaagaggtg aacaagtttg attgaaagac
      301 atgtaaattt attaaaatta ttaagtcgac aagaagactt taaacccgct tcttttttta
      361 gtgataaatt ggcagtgtcg accaagacca tttatcaaga tattgaattg ttggaagatt
      421 atgtagttaa ttaccaagta acaattgagc gattaccttc tttgggtatc aaactcatag
      481 gtgataggaa aaacgttgaa catttgattt catcggtaga aaattatctt gaaaaagata
      541 tttattctcc agaaaaaaga cgtgtcgaga tcattaaaga agttttgttt ggtgataagc
      601 ctgtttcttt aactcatttg tctcaaagtt ttatggttag taaaacatcg ttatacaatg
      661 acctgagaat tatcaataaa attattggca gtggagaagt taagttgcag tcatctgcag
      721 aaggaattag ttttactggt aatgaacaag caattcaacg agcaatcaag caacttgtat
      781 tctattatgc gaatgacatg gaatcaaaaa cattttttca agttttaaat atgttgtttg
      841 attcaaaagt tattagtgtc attcatgatt tgctattcaa tgattacagt gaactgactg
      901 aaaaggtttc tgattactat gttcggtcat tgatttctac tttagttatc caatgtaacc
      961 gtttactgaa aggtcatcat ttaactgttg aagaagaatt cctcttcaat agcattcgct
     1021 atatggaaac gtacattgtg gcaaatggtt taattgaaga attgaaggca aaattgaatc
     1081 ttccatttta tgacgcagat aaagaatatc tatgtcgtca actatttgca catcgtgtga
     1141 caaataattt aaaaaccagc aatgaagagt acgctatgag cgttcataaa ttgattgaaa
     1201 gaatgagtga gattgaaaaa attgatttga ctcaaaatga tcgattatat caatccttat
     1261 tgtatcatgt gccagcaatg gtccttcgtt taaaaaaagg tattaaaatt caaaatccgt
     1321 tattagaaaa tatcaaatct caatattcag aactctttag catagtatgg tacgccatgt
     1381 ccatccttga agaagaattt gatgtgactt taacggacga tgaagtttcc ttaattttga
     1441 ttcattttca gattgctatt gaagatcagt ccaaagcaaa taatatcatc attatttgcc
     1501 aatacggtat ttcttctgcg caattaattt acaataaagt tcgacggttt ttaccagcaa
     1561 aagataatgt agaaatatca actttagata agtttcattt agctgaaatt ggggaagttg
     1621 atttgattat ttcctctctt tcctttgatg caggtggtat acccttagta agggtatctc
     1681 cattggtaag taaaacagat tatatgaata ttatggaagc ttatactaaa tatttaatag
     1741 aagaaccttc gcgatttatt caaaatgaac tgattcctaa agcggttaaa gttcccacca
     1801 tatctaaatt tgttcaatca tctttagtaa aaacaggagt acaggtggaa agcaaagaag
     1861 aatgtttgga tttgatgatt tccgaactag aagccaattc attagttact gaagagtttc
     1921 gtgcttctat cttctctaga gagaaaatgg ggaatactaa tttagaaagt ggtgttgctt
     1981 taccgcatgc gaatccatca atggtcattg aatccaacat ttttattgta gcattaaaaa
     2041 atgcgattaa ttggggcgat cgaaaagtca aattagtcat tatggttagt ttagctgaag
     2101 aagatgtatc tgagattaga ggagtatatg aagaacttta ccaatttatt gggcaaaaag
     2161 aaatggtcga tcgcttgtta caagttcatg atagcgaaaa attactaaga atttttcaac
     2221 aaaaaggaga ataaaaatgt atctagataa agaattatgt ttatttcaat tagaagtgaa
     2281 agatcaaaaa gaattgtttc aagtaatgtc tgaacaatta aaaaacgctg gttgcgtgaa
     2341 agatagtttc ttagaaggta tcaccaaccg tgaacaagaa tttccaactg gattagaagt
     2401 aaatcaaatt gggtttgcta tcccacatac agattccgca catgtaaata gctctcaaat
     2461 ctgttttgcc tcattaaagg aaccactggt attttcagat atgacagata aatctcatga
     2521 aatacctgta cgtttagtct ttatgttggc aatgtcacaa cctcatgaac aaattgatac
     2581 actacaaaac ttagttagcc tatttcaaaa tgaagaaaaa gtaaatgaat tacttgcatg
     2641 taccacgaaa gaagcattta ttgagttagt acattctgca ggagtttatt aggaggaata
     2701 gagagatgga tattgtatta aatgcctttg aatggtttat tggattaggg tcaaacgtct
     2761 ttttaccact gattattttt gtaatcggga tattatttgg attaaaacct ggtaaagcat
     2821 ttgtttccgg cgttactgtt ggtatcggtt ctattggttt aggattagtt ttaagtttat
     2881 tatcagatgg tttaggaaca gcaattcaac aaatggggga acaatacggt ggtggcctga
     2941 atatcctaga tattggcgta ggtgttggtg gacctttggc ttactctaca tcattgggaa
     3001 ttttaatgat tccaatttca ttaattctta acttcatatt tgtggttttg ggttggacaa
     3061 aaacattgaa tgttgatatt tggaactttt ggttcgcaat tttcctaggt atgattactc
     3121 aatctgttac gggaaacttt tggtttggct taattggcgc gattgtcgca gtaattttac
     3181 aatggttctt agcagatcgt acacaaaaaa ctgttagcga atttttcggc tatccaggaa
     3241 tctctatcac acatatgatg ggattatcag gagtactatt tgccaaacca gtaaattggg
     3301 tttttgatcg tattcctgga tttaataaaa tagatgcaga tgcagaaaca ttaacaaaac
     3361 gtttcggtgt tttaggtgac acagttgtta ttggcctaat tatcggtatt gtagtgggta
     3421 ttatggcagg ctatgacgta gcaggaattg gaaacttagg aattatgact gcggcagtga
     3481 tgaagattat gcctaaaatg gtagcaatgt ttatggaagg tttaatgcca attgcagaag
     3541 cggcgaaaga atttacgaat aaaaagttaa atggtcgcca agtaaacatt ggaatggatg
     3601 cagcgttaac tgtgggtcat ccaactatta tgtcaacttc tctattgctt gtaccaatct
     3661 cattattgct agcactaatt cttccaggaa ataaagtatt accttttgga gatttagcat
     3721 tctttgcttt cgccatctgt ttaatgattc ctta
//
LOCUS       DACBYO010000162         3722 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.164, whole genome shotgun sequence.
ACCESSION   DACBYO010000162 DACBYO010000000
VERSION     DACBYO010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.164"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            72..155
                     /locus_tag="IVD26_002865"
     CDS             72..155
                     /locus_tag="IVD26_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAP6080767.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            280..1017
                     /gene="erm(B)"
                     /locus_tag="IVD26_002866"
     CDS             280..1017
                     /gene="erm(B)"
                     /locus_tag="IVD26_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAP6080768.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1280..2143)
                     /locus_tag="IVD26_002867"
     CDS             complement(1280..2143)
                     /locus_tag="IVD26_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAP6080769.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2145..2417)
                     /locus_tag="IVD26_002868"
     CDS             complement(2145..2417)
                     /locus_tag="IVD26_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP6080770.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2434..2643)
                     /locus_tag="IVD26_002869"
     CDS             complement(2434..2643)
                     /locus_tag="IVD26_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAP6080771.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(2742..3596)
                     /locus_tag="IVD26_002870"
     CDS             complement(2742..3596)
                     /locus_tag="IVD26_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP6080772.1"
                     /translation="MEKEKLKILEELRRILNNKNEAIIILNNYFKGGVGKSKLSTMFA
                     YLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKNGNLASSIIHLTDNL
                     DLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIIIDTVPTPSVYTNNAI
                     VASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFVPYLVDTDSATIKSN
                     LEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVLSMYENVFFEMIERI
                     IQLENEKE"
BASE COUNT         1144 a          653 c          576 g         1349 t
ORIGIN      
        1 aaattttgta taataggaat tgaagttaaa ttagatgcta aaaatttgta attaagaagg
       61 agggattcgt catgttggta ttccaaatgc gtaatgtaga taaaacatct accgttttga
      121 aacagactaa aaacagtgat tacgcagata aataaatacg ttagattaat tcctaccagt
      181 gactaatctt atgacttttt aaacagataa ctaaaattac aaacaaatcg tttaacttct
      241 gtatttattt atagatgtaa tcacttcagg agtgattaca tgaacaaaaa tataaaatat
      301 tctcaaaact ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta
      361 aaagaaaccg ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg
      421 gctaaaataa gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg
      481 tcagaaaaat taaaactgaa cactcgtgtc actttaattc accaagatat tctacagttt
      541 caattcccta acaaacagag gtataaaatt gttgggaata ttccttacca tttaagcaca
      601 caaattatta aaaaagtggt ttttgaaagc catgcgtctg acatctatct gattgttgaa
      661 gaaggattct acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact
      721 caagtctcga ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa
      781 gtaaacagtg tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg
      841 aagctatata cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact
      901 aaaaatcagt ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccgttact
      961 tatgagcaag tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc
     1021 tatgagtcgc ttttgtaaat ttggaaagtt acacgttact aaagggaatg tagataaatt
     1081 attaggtata gggcacctct aataactacc aattaattca cctcaaaatg aaattagaaa
     1141 aaaacagcga aatttttaaa tctatttctt atcgatacaa attcctcgta ggcgctcggg
     1201 accccaacat gaggaaatgt ttttataaaa aaagagtagt taccgttttt tggtaactac
     1261 tcttttcctt ttttaaggtt taaatacctg gaagtttagg tgttttgggt attggtggtg
     1321 taggtagctg caagctttcc attttttgtt gaattgcttt aaattcaggg gtttcttggt
     1381 gttgattttg aaccattttt tgctctattc tctccaaagt cggttgaatt tctttccctg
     1441 atactttacg atttaattct ctttctaagg tctctttcgg actaatggaa ggcgtttcta
     1501 agcttgaata gagtttcact ccttctctat tgtaaagcct tatatcgcta aataagcccg
     1561 ttttatgaag ggtttctaaa ttggtcggta agtttttgac aacaatatca tgcgcttgtt
     1621 ttggtgttgc cctagctgtc attggatcat ctgcatacat ggtttcatat cgttcaatcg
     1681 ttcctaagta tgattcaatt ttcggtactg ccatgacgta tatttttgtt tcataacctt
     1741 tagattgaag cattgtggct gtttgaatgg gaacgtctgt tgttcgtcct gttccttcaa
     1801 tcactaaatt atagccttga tcgcttaaac ggctaataag tgcttctgtc atgcgattcg
     1861 aataaggggt aacgtgtttt actacgtctt tttcatagag tttcactaat tcgtcaaaat
     1921 ttgggtgctg ttgtttaaag gtatcattat caatgacaat aacattccct tgtgtttctt
     1981 caaaaattgc tgatcgcaaa ctggttttcc ctgaccctgg ttgcccacca agtaaaaaag
     2041 cggttggcga ttcaaccgct agtctatttt tagttagtcg ttcaacattc ttttctaaac
     2101 gatcttcaaa ttgcttttcg gtgaagtcag taatattcgc catgttaagc cactttctct
     2161 ttattcaaaa tttgttttga atattgattc attgaccgcc aatactcatg aatagcttgt
     2221 aattcttcaa atggttgttg aaataaatca acttcttgtg ccacttctaa ttgatttaaa
     2281 agattcactt ctagtaaacg agtattttta gtatctagtt catgattcaa aacataattt
     2341 aatacccgat tataaacact tgccgataac tcattaatga tttcaatttc aaatgttttt
     2401 tcatacgtaa ctgccatttc attttcactc cttttaaagt ttgtcaggta aatatttccg
     2461 tatatattct tctaaggctt gatccataac ttcttttacg tttccgccat tctttgctgt
     2521 ttcgattttt atgatatggt gcaagtcggc acgaacacga accgtcttat cccccattat
     2581 atcttttttt gcgctgattg gcgtatcatt tcgttttgct ttctgtgcgc ctaaatttcc
     2641 cacgatcgct cacttctttc tatttcttct tactatttat tttatcatca cctatcacaa
     2701 atcacaagtg atttgtgatt aatcacttgt gatttgtgat tctattcttt ttcattttct
     2761 aattgaatga ttcgctcaat catttcaaaa aatacgttct catacataga caaaactttt
     2821 ttgtcatagc ctttgtgttc tgtaatgcca tttttagacc aagtacttac tttattactt
     2881 cgcttgataa tatttcggaa aaccaaatta tcctctttat gttctttgta cagttcttcc
     2941 aggtttgatt ttatcgttgc gctgtccgta tcaactaaat aaggaacaaa accaatcata
     3001 tctagtccag ggttaaactg ttcttgcaaa tcaatcaaat aggaaatata gttttgaatg
     3061 ttgtttgtac tttcttcttc tgcttgtaaa gggatcataa cgtaatcact cgccacgatt
     3121 gcattatttg tataaacgct tggcgttggt acagtatcaa taataataag atcatagtca
     3181 ctttttaaag gtgctaaaag agtagcaagc aatctacttt cattttcaaa cgtccatgag
     3241 cgagttaatt ttggcagtaa catcaaatca aacgtgccag ggatcaagtc taaattatca
     3301 gtcaaatgaa taatagaaga agccaagttt ccatttttca agccttcata aaaattgaca
     3361 cgtggcaatt ctacctcaaa agtttttgct aagtcttttg tcaatgttgc ctgtaagtcc
     3421 ttatcgatca ttaaaacttt taaattcaat ttgtctgtca agtaagcaaa catagtcgat
     3481 aatttggact ttccaacacc acctttaaag taattattca agataataat tgcttcattt
     3541 ttattgttta aaatacgtct taattcttca agtattttta gtttttcctt ctccataact
     3601 acgccccatt ctttttttgt atagtaatat tgtatcatta agaatcacaa atcacaagtg
     3661 atttgtgatt aatcacttgt gatttgtgat aagtgatttg tgattaatat ataaaagccc
     3721 tc
//
LOCUS       DACBYO010000163         3569 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.165, whole genome shotgun sequence.
ACCESSION   DACBYO010000163 DACBYO010000000
VERSION     DACBYO010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.165"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            86..1374
                     /locus_tag="IVD26_002871"
                     /pseudo
     CDS             86..1374
                     /locus_tag="IVD26_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(1500..2579)
                     /locus_tag="IVD26_002872"
     CDS             complement(1500..2579)
                     /locus_tag="IVD26_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP6080773.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(2682..3122)
                     /locus_tag="IVD26_002873"
     CDS             complement(2682..3122)
                     /locus_tag="IVD26_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP6080774.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(3179..>3569)
                     /locus_tag="IVD26_002874"
     CDS             complement(3179..>3569)
                     /locus_tag="IVD26_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAP6080775.1"
                     /translation="KMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPEQLFAAGF
                     SACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLSLEETQEL
                     LEAAHKVCPYSKATAGNIEVTLKAVSE"
BASE COUNT         1333 a          689 c          629 g          918 t
ORIGIN      
        1 tttagacaaa aaaacagtaa acatataggt agaatctcta ctatcttatt tcttgcatac
       61 aaaaaaatca aggagtgaga gagttatgag atattcaacc atcttaatat caacatttgc
      121 agccttaagc ttatcgctta ctataaatca gacagtccac acagaggaga tagaaacagc
      181 caaatggaca gaaaccaagt gggccaacgt caatcgaatt acctttcagg atgaattttc
      241 atccttcaat tcaggagtcg caaaattaag aaaaggacaa acagcgacca tcaaagcaaa
      301 aattgactat tcaggagact tagcacctat actacaatca gctgttacat ttgagaatgt
      361 tgatcccgct ttgtcgattg gctatgacga gaacactttg actatccaac acaagcaagc
      421 gatatttacc ttcaccgtta cattaaatca ggacttgtta aaaccagcgc tttttactgt
      481 caaggtatca gatggactac cgaacgatca tcatcattta acgccgtata gtcagcggca
      541 gacaattgag caagattcag ctatcgactc aggaggagat cttgttgaag aaccaacaga
      601 taaaccagaa aatgaaaata agccagaagt accgcctaca gaaaatccag acggagaaca
      661 gaaaccggaa atagaacctg gagaagaacc cgatacagaa actcaaccag agccagacaa
      721 tgaatcaaaa cctgaaataa cccctggaga aaaaccagat gtagacccag aagaaaaacc
      781 agatgtgact ccagaaccag atacggattc tggaaaccaa acagtaccgg aaacaaatcc
      841 agacacagat aatgaaactg aaaatccaga aaaaccagag gtagccccag aagaaaaacc
      901 agatgtaact ccagaaccag atacggattc tggaaaccaa acagtaccgg aaacaaatcc
      961 agacacagat aatgaaactg aaaatccaga aaaaccagag gtagatccag aagaaaaacc
     1021 agatgtgact ccagaaccag atacggacgc aagagaccaa ggaataccag aaaaaataaa
     1081 caaaaaaaca attcaagagg atggaaaaaa agagagtaaa aaatcaaatc tagcaattct
     1141 aaaaataaat gaagagcagc tgaataaaaa atcacgaata tttgatagcg cccaatcagc
     1201 tgaaacctta aaaagtagca aggatacaac ctttgctgtc ctgaaacgaa aaataaacag
     1261 ctaccaaaat ccggagagtc acaaaacaaa gttatactgt ggagcggaat cattctatta
     1321 agtatagcaa caatgctttc tgcaaaaaga tttaaacaaa acagatctct ctaacatttg
     1381 aataatgtct gtgaacgcat ttttcaaata aaaagaaata tccagaaaat gaccccaaaa
     1441 taccagattg aaatctgata tttggggtcg ttcatacttt atctttcttc atatttattt
     1501 taagggatat ctgtttcttt tggaagatgg ttcgggatct ttttcacttt caatacatct
     1561 aaaaagaagg taaagatcgg aatgccgaca atcaagcccc aaacgccaaa gaaccgttcg
     1621 ctaacaagta agaccacaaa tgtataaaaa atcggcagtt ctgttttgct ggacatcaac
     1681 ttcggattca gcacataaga ctcaattaga tggacaatca aaatcgtaat caggatataa
     1741 acaacatctc ggatgcctcc ttgggaataa gctatgaaag atagaggaat acaagaaatg
     1801 ataacacctg ctactgggat cagacttaaa atgaaaatca tgatcgctaa actcagcagc
     1861 tgatgaaagc caaatacagc caaggcgatt gtagtgagca acgtatttaa aagagcgaca
     1921 acaaattgag cttctaatac caaaccaaat gtattgacaa acttatcggc aaaatagtaa
     1981 atatcttgaa agaaccaaga aaattcactt tttaaaaaca atcttgagaa tacaattgtt
     2041 tttttctttt caatcataaa aaagaaactt aagatgaatg acatagcaaa cgccactgcc
     2101 atttttccta tatcctgtaa atagccaagc gcaatcgaag cgccattttg aagctgttca
     2161 aaaaaatcgt ttcgctcaat ataagtatgg atatattgta aaacaggatc tgcatctttt
     2221 ggctgatgct cgtaaaaatt aataacggac tggatcatgt caaatgtttg atgaataagc
     2281 atcgggatat actttgtgaa tgccagatag ataaggtaaa cgatcagtgt ataaatcatg
     2341 atagctaaaa cacctgtagg gattcggaca aatcgctgaa tgatttgaac aagatgaatc
     2401 atcaaataag taaagataaa tgtgagcaaa atggttgtaa tcatacttct aactaagaaa
     2461 agaacaaaaa cgacaaataa taaaacagtg agacggcgta ttttttcatt cgccaaaaaa
     2521 cgctgataaa cggtcaaatc gacaacctcc aaataacaaa aaataaacac gttattcatt
     2581 atatgatgga atatgaaaat aagaaagagc aaaaagaaaa accgctaaat gacgttatct
     2641 tatgagttgg ttttcctcat aaaatcgttc atctagcagt ttcagccctt tttctggtct
     2701 tgatgaaaat tatctagcat ttttcgggtc agatgttgca gtgtatccaa ttcttcctgt
     2761 tcaagtggaa gataagactt gatcttttgt ggaatacctt ctgcttgttt ttgcaacgca
     2821 gcaccttgag cagtcagcgt aacatttacg attctttcat cacccgtttc acgctgacga
     2881 ttaatataat ttttttctgc taactttttt agtaagggag tcagcgtacc agaatccaga
     2941 cacaaatcat ttcctagctc tttcactgaa gtctttttct tttcccataa aactaacatc
     3001 acaagatact gggtataggt aagattcagc ggcttgagga ggggagtgta gtgtctaatg
     3061 atttctttag aggcggcata taaaggaaaa catacttgat taactaaata tagatcttcc
     3121 atttttccac ctccgctgtt ttactatagt gtatcatagc ggatttacac aaaaaagtct
     3181 attcactaac tgctttcaga gtaacttcta tatttccagc tgtagctttt gaatacggac
     3241 acactttatg cgctgcctct aataattctt gcgtttcttc cagagaaaga ccttcgatag
     3301 atccttcaat ctctacacct aagacaaagc tcgtttcact ttctgaataa agggaaactt
     3361 gtgcactgac agtagaagcc ccagagatat ttttttgctg tttgatcaat tctaatgcac
     3421 tgttaaaaca tgcactgaaa ccagctgcaa acaattgttc agggttggtt gcattttcga
     3481 cgcgtttacc aggagctgca atattcaatt cgaatgtacg atcgggatta tgcacttctc
     3541 cagagcgtcc gcctgtgttg atcattttc
//
LOCUS       DACBYO010000164         3566 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.166, whole genome shotgun sequence.
ACCESSION   DACBYO010000164 DACBYO010000000
VERSION     DACBYO010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.166"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            236..1036
                     /locus_tag="IVD26_002875"
     CDS             236..1036
                     /locus_tag="IVD26_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HAP6080776.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
     gene            1052..1930
                     /locus_tag="IVD26_002876"
     CDS             1052..1930
                     /locus_tag="IVD26_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAP6080777.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            1943..2923
                     /locus_tag="IVD26_002877"
     CDS             1943..2923
                     /locus_tag="IVD26_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAP6080778.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
BASE COUNT         1225 a          574 c          732 g         1035 t
ORIGIN      
        1 gtaacccgta ccttttatat ttaaagaggt tgtttttcta taaatcgttg taaagaatga
       61 ctaagttgta ttattttttc acaaacattc atattataat gtttcttttt aataaaaaga
      121 ttgtttttaa gctaattatt atatgtgtgt tattgaacta actcttgaca gataatcaaa
      181 aagaatttat agttgttacc gtagtagcta ctaaaaataa agtgaggatt aatcaatgga
      241 aacgattatt caaatcatga aaaaatatga tttttcagag atggagacaa gagtgtatac
      301 cacactatta gaaaaaggta atcttacagg atatgaagta agtaaaatct caggtgtgcc
      361 acgctcgaaa gtatataata ttttggaaaa actattaaaa aagaatttga ttgtcgttaa
      421 taaatcagaa cctaaacttt atcatgccat ctcggcaaat gagtttttag agaaattaga
      481 aaaaagtgtt aaaaatgatc tttcttttct taccaagaat ctagggatga tcaaagaaaa
      541 agatgaagaa gaaatgctgt ggaaagttga tggtatcgag tatgttctgg ataaagtaga
      601 gcatttggtg aaaaacgcaa aagaaagttt gctcattcaa gtttggcatg agaatttcac
      661 ggattcacta ctaaaggcat tgcagcaagc tgaaaaaaga gttgataagt ttgtactgat
      721 tttattcagt tctacccatg aatatgatct tcccttagaa aagtattata ttcatggttt
      781 tgaaacagac aaacttgctg actttggagc aagatggatc aacatcgtcg ccgatgagca
      841 agaagtcgtg tttggtacca ttaacgaaga actgcaatca accgatgtca cttggacaaa
      901 aaaccacgcc atggtcaatc tagcaaaaga atatgtcaaa catgatgcat atacactaaa
      961 agtgattgca gaatctcctg aagaacttaa agcaaaatat ggtgagggct ttgagggaat
     1021 cagaaagatt tactagtagg aggaattttt tatgattcgg aatattttgc tgacactaat
     1081 tgtcgcaatc aatctatatt ttattattta ctttctaaga gaccttttca aaaacaaaca
     1141 aaatttcaaa gaagaaccag gggatatgcg tctgttgccc ttcacgtcat ttatcatctt
     1201 ctttctttca acatttggcg tttccgactt tgctatcgga accgtccttt atccaaagtt
     1261 gaaatgggtc agcatgaaaa aactacccgg aacgttgaat acccaatgtg tagtaccggt
     1321 agccgtcatg gcattgtctt acatcactgc catcaacgta gggatcaaga cactagctgt
     1381 ttgtattatc tgccaaatta tcggtgcata tttaggacca agatttgtcg tgaagttacc
     1441 agagaaaacg atcaaactgt ttgtcggcat aggattggtc attgctgcat tgttgatttt
     1501 tgcaggacaa atgaactgga ttccatcaaa cggaacagcc agtgaattgt atggcggaaa
     1561 attaatcttg gcaggatttt tactctttgt ctatggtgca ttgaacaata tcggcattgg
     1621 ttcttatgcg ttaacgatgg taactgtcta cttgctaggc ttgaatccag ttgcagcctt
     1681 tcctattatg atgggggctt gtaccttctc agtaccgatc ggcagtgttc aattcattaa
     1741 atttaatgaa tacagcagaa aaatcacact ttttacttca accttcggtg tattgggggt
     1801 attggtcgct gtattcctag tcaaatcttt agatacctat atcctgaaat ggatcgtgat
     1861 tttggtctta ctatacagtg catatacgat gttgggcagt caattaaaaa aagttacagc
     1921 agctaattaa ggagcgattc aaatgttatt tcttaaaaaa gaagatatta tcaaaagttt
     1981 ttcaatgaga gaagccatcg atgcggacaa aaaagcactg tcattgtatt cagcaggaaa
     2041 ggcaagtgtg cctcttcgca ccaatatcga tgtgccaaaa agcaacggac aaagcttata
     2101 tatgcctgct tatgtagaag gtggcgaagg cgcgctaggt gtcaaaatcg tttccgtgta
     2161 tcctgaaaac atcaagaaaa acttaccaag tgtaccagca acgatgatcg tattggatcc
     2221 agaaacgggt atggtatccg cttgtttgga tggtacttat ttgacacaat taagaacagg
     2281 cgctgttcaa ggagcagcaa cagaacttct tgcaagagaa gatgctaaaa ttggcgcgct
     2341 gattggaacc ggcggacaag cacagtcaca attagaagca atgttgaccg ttcgtaaatt
     2401 agaagaagtt cggatttttg atattgattt tgagcgtgcc agccaatttg ctgaaaaaat
     2461 gatgcaacaa ttttctgtaa cgatgcgccc aacaaaaacc agtcaagaat gcgttgaagg
     2521 agcagacatc attacaagtg tgaccacttc aaaacgtgcg acattctctg ctgagtgggt
     2581 caaaaaaggt gcgcacatca atggagtcgg tgcttacaca ccggaaatgt gtgaaattcc
     2641 acgagaaata atcaaagccg cagatgttgt tatttttgat accatggacg gtgttctaaa
     2701 agaagctggg gacttcattt caccgctgca agatgggtat attcaaagag acagctatca
     2761 tggggaacta ggccaactga tcaatgaaga attgatcggt cggacaagtg gagaacaaat
     2821 cacgatcttc aaaacagttg gttcggctgt attagatgtg gtagttgcga cagaaatcgt
     2881 taagaaagct aaagaaaata atttgggaaa attgattttc taattaaaaa ggctgaaatt
     2941 aaaaccttta ttattgcgtt taaaaaaaga aaacaaagaa gtttgtaatc aaatggaaac
     3001 tgaccccata atttaaataa aataaaaaac atctcttgtt gaattctagt aatgaagcga
     3061 ccctaaaact tagaccaaaa aatctaactt ttgggtggag ttgtcaagaa aaaccgggca
     3121 cttagttaaa aaataagttg gacgggttat actaaaattg acaccaaatt aagagaaagc
     3181 gaagatctgg attatgccaa gacgttcatt tgatgaaata tttaaaatta ccgctgtaaa
     3241 actggtaacg gaagaagggt tttctgttaa agaagttagt ctatagctag aagctcgctc
     3301 taatagcgtg tattgatgag ttcaagaagt tgaaaaatat ggataacgta cttttctcgg
     3361 tagaggaagt catgaaatcc attcgcagaa atgaaattac acgcttagaa aaagagaata
     3421 aacggttaaa agaataggta gaactcctaa aaattaccga agtcttcctg aaagaaaagg
     3481 ctcttcgtca aattgtgttg gcgaagacaa atttgaataa aacttagtcc gatatgcggc
     3541 gcgttctgtg cgccgcatat ttttta
//
LOCUS       DACBYO010000165         3550 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.167, whole genome shotgun sequence.
ACCESSION   DACBYO010000165 DACBYO010000000
VERSION     DACBYO010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.167"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..1131)
                     /locus_tag="IVD26_002878"
     CDS             complement(<1..1131)
                     /locus_tag="IVD26_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP6080779.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENAQTVDKVHFMDD"
     gene            complement(1261..2637)
                     /locus_tag="IVD26_002879"
     CDS             complement(1261..2637)
                     /locus_tag="IVD26_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6080780.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2637..3293)
                     /locus_tag="IVD26_002880"
     CDS             complement(2637..3293)
                     /locus_tag="IVD26_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6080781.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3303..>3550)
                     /locus_tag="IVD26_002881"
     CDS             complement(3303..>3550)
                     /locus_tag="IVD26_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6080782.1"
                     /translation="SIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNIT
                     TLGQSYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
BASE COUNT         1098 a          658 c          474 g         1320 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgcgcattc tcattagaga acgctccttt
       61 ttttgtgact tttctgaagc tggagtggac actttcaacc gcattggtag tgtacataat
      121 ttttcgaatg gcactaccat aatcaaatag ttgttcaaca tgagaaaagt ttcgtttgca
      181 tacatctact gcaccagaat aatgagacca ccgattttga aaactgtcga aggcagcgtg
      241 tgcagcgttt aaagaagaag cactgtagaa ttttttcatg tctcgacaga cttccttata
      301 atccttactt gggaggtatc gtaacgcatt tcgaacaaga tgaacaatac agcgctgcac
      361 aatgacagaa ggaaaaattg cttttgcgcc ttctttgaga ccggaaacac cgtccatcga
      421 aatgaaaaaa acatcttcta caccacgtac tttcagttca tcaaatactt gcatccagcg
      481 atttttagat tctgtttgat tgagccatag gcctaaaatc tccttgtttc ctttaagatc
      541 atagccaaga atggtgtaca cagcatattc tttagcttca tagttttcgc gtaaagtgac
      601 gtacatacaa tcaacgaata gaaatgcata acacttggct aatggccgag cttgccattc
      661 ttccaattca ggaaggacgg catccgtgat atcagaaatc atttcgtggg aaatatcaaa
      721 gccgtaaata tcttcaacgg ttgcggcgat atcgcattga ctcattcctc gtgcatacat
      781 ggaaagaacc ttaccttcga tgtcggagac atctcgtttt ctattaggaa tcaactcagg
      841 ttcaaaagaa gcctcccggt ctctgggaac atcaatgttt actttaccaa agctcgtttt
      901 aagcgtctta ttgccataac cgtttcgtcg attgtcatgt ttctttggct ctttagaatg
      961 ggcgtcatac cctaaatggt tattcaattc tccttgaagc attttttcaa ataagggacc
     1021 aaacacatct tttaaaacat cttgcatatc ctctacagat tcgggttgat aagtattcaa
     1081 aatggattca gctaacttct cagcatcagg atttcttttc tttctagcca tcgtgtaatc
     1141 acctcttgat cttattttag aaaaataaaa accgtgaagc aaccacccgc ctaggattga
     1201 tggttactta cacggtttat attacactct catttttggt gctaaaaagc accgaaaatt
     1261 ttaattattg tcaattaata attcttttgg attccttctt aatatattga atgaagaaat
     1321 aatcaatgat acaagaagta ctaaactcat aaatataact acataaatca tgaatttagg
     1381 taatacattg atatctaaac ttgataatgt cttgttaaat ccttcagctt ctgccccacc
     1441 acctaattgg ctagatgcag attgtttagc tatttgttta gctatatcac cagtaacctt
     1501 attcaatata ttattcccaa gcttgtcagc tgtatattga gctaagaaat aggaaccaac
     1561 gaatgcgggg attgatataa ataccatctc aattaggaat tgaccaaaaa tttctaattt
     1621 tgatatacct aatgatagta atactgctat ttctttcttt ctagcattca tccataagaa
     1681 taataataat gaaactacaa ctcctgcaaa tattaatgag ccaaaaaata atttatttga
     1741 aattgagtaa atacctgata tagattgttg taatgcaggg taatttgatg aacttttaat
     1801 caaattatat tctctccaat ttatatctaa tttcccaaga tcttttatta cactatcaag
     1861 attcttatca ccttttacaa agaatgttgc atcttggtat acagctgtat cttcggtatt
     1921 accataaact ttagcagctg tatgaatatc agtgattaat gtattttcgt atagttcttg
     1981 tgctgcactt actccaccgc tattatgccc atcgaataga cctttaattt ctacttctac
     2041 tgtttcatct gcacctttct cattatcagc atcaaataaa ttagatttta tttttatctt
     2101 atctccaact ttaaggttat ttttttcagc taaatcttta tgcattaaga ttttattttt
     2161 atcttcattt tctaaatgct ttccttctac taatttatat gcttctgata caaattttgt
     2221 ttcttttgtt gagtcgttaa ccccagttaa cataactgtt cttttaaaat tctttgctct
     2281 ttcaggtgat tgattcgcaa gagtctcttg agtttcaata atatcataat caactaaatc
     2341 tgcaacactg tttattcttt ttacatagga gtctatacta tctgtttgag atatcttttt
     2401 aatatcttca ccttttacat ttcccccacc tctaggtgtt cctggattta cttgtctatt
     2461 tatctccata gaaaaactat ttgttatatt agcaaatgtt tcttttgaag ctctgtccgt
     2521 agcatcttta atagataaac taatgagact taaagttgac atagataaaa taactaatat
     2581 gataattaat gattttaaac tttttctagt tacataagca aatgcatttt ttatcattat
     2641 tcaacctcca aattcatttt atttactttt ttcaactttt taccacttag ttctaaaatg
     2701 atatccgcag aatctgctac ttccttacta tgtgttacaa ctattacaca tttatttcta
     2761 tctttagcta atgtctttaa tatattaatt atttctccag cagtaacact gtctagatta
     2821 ccagtaggct catcagctag tattattgga gcatctgata ccaatgctct agcaatagct
     2881 actctttgtt gctgtccacc agataatttc ataacatttc tttttatttg ttttttatct
     2941 aaacctagtt caaacaagat actttcatct gctgatttat ttactaatct aatattttca
     3001 attggtgata aataatctat taaattatag ttttgaaata ctaaagatat attatttttt
     3061 ctatgattac tatatccttt attttgtata tcttcattct taaacaatat ttttcctgtt
     3121 tgaggtttat caagtccagc aagtaaggaa agaagtgtag attttcctgt tcctgacttt
     3181 cctactatcg cataaaactt cccaagttca aatttttgat ttactcctga caaaactttt
     3241 tctttagaat ttgcataact atatgctaca ttctttattt ctaatatatc cattattttc
     3301 tcctaactta tttttgataa gatttcttta ggcttcttga ttaacattaa tgaagaagca
     3361 aatacaactg ataaaacaat aatacttatt aatattaaat aactttgtcc aagtgttgtt
     3421 atatttgaca taaaactact attatttatt aaacttccac cggaaatcat tgaatcctct
     3481 gagttaatga atccatctac aattactttt agtaatacat ttcctaaaaa taaggaagat
     3541 attatacttg
//
LOCUS       DACBYO010000166         3542 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.168, whole genome shotgun sequence.
ACCESSION   DACBYO010000166 DACBYO010000000
VERSION     DACBYO010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.168"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            94..975
                     /locus_tag="IVD26_002882"
     CDS             94..975
                     /locus_tag="IVD26_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP6080783.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            988..2598
                     /locus_tag="IVD26_002883"
     CDS             988..2598
                     /locus_tag="IVD26_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAP6080784.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2675..3334)
                     /locus_tag="IVD26_002884"
     CDS             complement(2675..3334)
                     /locus_tag="IVD26_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP6080785.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
BASE COUNT          980 a          681 c          701 g         1180 t
ORIGIN      
        1 taaaaaaaag ttttataaaa aggtataaaa cctttttatt aaactattta atcttgttta
       61 gtatatattt ttagaaaaag gagtggggtt tttatggcag aaatcgtcaa agtcacacat
      121 ttgaaaaaga gctttggtcg tttcgaagct ttaaaagatg tctctttcac cgtacattca
      181 ggtgaagtcg ttggatttat cggaccaaat ggttctggaa aatccacgac gattcggaca
      241 cttttaggga ttataaaaaa agacggcgga acggcaacga tttttgggca agatgtatgg
      301 gaagatagtt tatctatcca tgaacgtctt tcttatgttc caggcgatat ctctttgtgg
      361 ggaaatttga ctggaggagc gatcatcgat ctcttcatga agcttcatgg aaaagggagt
      421 gctcaaaaaa aagatgaact gattcaacgt ttctctcttg atcctaagaa aaaagcaaaa
      481 aactattcaa aaggaaatcg ccaaaaagtg ggcttgattg ctgctttggc tgttgattcg
      541 gatctctatt tatttgatga gcctacttct ggtttagatc ctttgatgga aacgattttc
      601 caagaagaag ttgaaaaatt gaaagaacag ggcaaatcca tcctactttc ttctcatatt
      661 ctcagtgaag tcgagcgact agcggataaa gtcgtgatca tacgcgaagg aacactcgat
      721 gaagaaggaa cactcgatga attgcgtcat ttgactcgtt cgaccatcac tatagaaaca
      781 gaagcagaga atagtcactt agcacaattg aacggtgtcc atgactttgt gcaaaaaggt
      841 cacctcgctc aatttgctgc tgataacgaa gctttcgatg tgattttagc tgaagcgtcc
      901 aaattaggtg tgaaaaaatt tgaatctatt ccaccgactc ttgaggattt attcatgaga
      961 cattatgaag gatgaggagg aagcgaaatg actgataaat tttcacgctg gtccaccctt
     1021 ttttctcaaa accttagccg tgactggaaa aagatcctga tatggctagt cggtgtcact
     1081 gctttttctg gtggttttgt ccctgcgttt gaagaattga cttccggaca aggattagct
     1141 ggattatacg aaaccttgca aaacccggca atgattgcaa tggtcggacc aactccagct
     1201 tcgaatgctg ctgagtatac tttaggagcg atgtatgcaa atgaaatgtt gcttttttgc
     1261 agtttgtttg ctgctgtgat ctctgtttta cacgtggtga gccaaacgag aaaaaaagaa
     1321 gaacttggtc tgattgaact tattcgttcc tttcgagtcg gacgtcaagc aaactcttta
     1381 gctgtcatcg ctgaaagtat tctgatcaat ttgcttttag caatatcgat cagctgtacg
     1441 atgatttttt tccaagcgga ttcgatcact gcagaaggtg cttggctttt tgggctatct
     1501 gtaggtagta tggggatttt ggggagtgcc gttgcactgt ttgctgcaca actgatgcca
     1561 agttcagcca gttcgaatgg tctgtcttta gcgtttttag gtggacttta ccttctacga
     1621 gcaataacag atgtagctga ttcctccctt tcgatgtgga atcctttagg ctggtcttat
     1681 ttgacctatc catttacaac taacaactgg attcctttgc tttatttgtt tttgttcagt
     1741 ctaatcttga taatcagttc atttgtttta gaggaacatc gagatttgaa caccggctat
     1801 atccccgaac gtgaaggaaa accgtatgct aaacgttctc ttttatcctt gcgtggttta
     1861 ttattctatc taaataaagg gatgacaatc agttggctta tcacttttgg tttgatgggg
     1921 gcggcatacg gctctatcta cgggaatatg caacagtttt tagaaagtaa cgacttaatg
     1981 aaacagatgt ttatccaatc tggcgtctca attgaaaaaa actttacaag cacgatcatg
     2041 gtagtcttga tttgtctagc tgctatttta ccaattgcta gcatcaatcg tttatttaca
     2101 gaagaaaccc acggacgtat gaatcagctg ttcgcaacaa aaatttctag gaaccaactt
     2161 tattggacca atatgttact agctattcta tttgctatat tggcaatcct gattagttct
     2221 ggtgcactag ggctttctgc tttggcttcg atgaaggatg cgaaagacat ggatctattg
     2281 atgtttctta aagccgggtt caatttcctg cctgccgttt tagtgtttat cggaattagt
     2341 ggctttctat tcggatggct tcctcgaatc ggtaaacttg cttatatcta cttagcttac
     2401 tcctttgcac tcaattactt tggcggaatt ttggatttac cagaatggtt ttccaaaaca
     2461 gctgtcccta gctgggttcc acggatgcca aacgattctt ttgatctttc cgtgttcctt
     2521 acgttatcat gtatcagcct tgcactgttc gtccttggtt ctattggtta taggcgaaga
     2581 gacttactag aaggataata aaaaagcatg tacaatttca tgctagcctc caaatctggg
     2641 tcaaaaatcc aacatttgga ggtcattttt ttatttacaa gtcttctaac tgctctttat
     2701 caatgatcca gacttctcga ttctttcttt ttacataacc attctcctct aataatttaa
     2761 attttctaga taaagtttcg ggggtcgtac cgataaatgc agcaagttct ttcattttca
     2821 ttggcaggaa aaagtgatcc ttccctgtcg ctttagctaa gtcaagcaga tagacagcga
     2881 ctcgttcttc tactttttcc atcatcaaaa aagttgtctg ctgctgtact tttgttaatt
     2941 tctcaacgtt gattgctaaa agtttcagac taagggcggg ataatgcagt aagagttccg
     3001 agaaatcttt ttgtctcaat atgcaaattt ccgttttttc tagtgcttcg ccaaataaag
     3061 actcatttgg aacgcctagc aactggctct ctccctcata tccgcccggc tctattactc
     3121 gtaaaagctg ttcctttccg ctagcagata attgatacac tttcatactg ccggaggcca
     3181 cgatcactaa ttgaggttct ccattcggcg caagaatctg ttctcctttt tccacatagt
     3241 gatgtttgac aagtgcgtgt actttttctt gatcttgctg tactaagtga ttgaacaaag
     3301 gaacaaatga aacacataaa tgatcatgac tcataatctc tcctccttct aaacagctat
     3361 ttctaataaa gaaacataac ttcccttatt ccaactgata attttctttt atcatagcat
     3421 aaacgtcaag cgaaccagat accagcaaat agagtggatt tctttttgtc ccttgcttta
     3481 ttttccttct tttgagacct taagtaattg attcctatca attttttaaa tatttacttt
     3541 tt
//
LOCUS       DACBYO010000167         3540 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.169, whole genome shotgun sequence.
ACCESSION   DACBYO010000167 DACBYO010000000
VERSION     DACBYO010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3540
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.169"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            1005..1331
                     /locus_tag="IVD26_002885"
     CDS             1005..1331
                     /locus_tag="IVD26_002885"
                     /inference="COORDINATES: protein motif:HMM:NF013698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP6080786.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            1339..2247
                     /locus_tag="IVD26_002886"
     CDS             1339..2247
                     /locus_tag="IVD26_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP6080787.1"
                     /translation="MCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSEKNRALNCLT
                     VSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEEIQAAVEGAI
                     SVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGLDTQPITAIA
                     ILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKPLLVQIANAL
                     LRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSAKGYLEPKPA
                     KEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            2876..3127
                     /locus_tag="IVD26_002887"
     CDS             2876..3127
                     /locus_tag="IVD26_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAP6080788.1"
                     /translation="MKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESLD
                     SFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
BASE COUNT         1110 a          693 c          620 g         1117 t
ORIGIN      
        1 taggttttgg acaataagga atgacttttt tcttcatata aatacctcat ttaactattt
       61 gatatcatca cattatcaaa aaaaataggt tttttattaa aactatcttg acctttcggg
      121 agatttcact gtgatttatt tttattccca tacttttttc gttggtcact ttcgtatacc
      181 taatctaagc gatcatcggc gacggtgctt ttacaacgaa tggcaggaca aaacaagggg
      241 cggaaaaact tttttgccta tttcataaaa aactttttcc tacagcaatc ccttgttttg
      301 tcctaccaca cgttgtgaac ccaaagcacg ccgacgaacg cttagctata cgaaaatgac
      361 ctccaaaaac aaaaaagtga ggtgaataga aacaaaaaga aattgaaatc tcccaaaatg
      421 tcgtccgcct cggagacaac ttgctgctga aaatggttgg ttaattcatt taagtattaa
      481 ataagataaa tcatcaaatt aatcggaaaa atagcatgat tggccttatc aaaaataaac
      541 tgtaaaaact tatatttcta tgagtggtgg aacaatgcta ataccaaatt aatttatcga
      601 ttacccacct gcacaaacca aagatagcat tattaggaaa cgaatcaatc agcgaatcca
      661 gcattataat gaggatacta aaaataaagt tttcataatt ataaatccgc cttcctacga
      721 aaggcaccaa tgaggtgatg aaaaccttag agcgctttct ttcttttttt attccgtgtt
      781 accctttcct tgcaggtccc tggtacacta cagaacccga ggaggtgagt ggcggggctg
      841 tatagcggca accccgcata attatatggt gtcggtcatc cgttaaggca tcaatgaatg
      901 gcgcaaaccc gtagcccgta aacttatctc ttccgaagtt gactcgattt cgccggatga
      961 ccagtcccta ccaaacctgt actatttttt tacaggaggt tgctatgttc aaaatctttc
     1021 gtaaaaattg ttgtggcttg gatgtccaca aaacgtggat ctatgcgtgt atcggaatca
     1081 cagatgcgaa tggtcgtaca gtgtataagc aagctcgctt ctcttccttt acaaaaggtc
     1141 tcaatgaatt agctgaatgg cttgctaaat acaactgtaa ggatgtgtgt ttggaatctt
     1201 ccggtaaatt ttggattcct gtttttaata ttcttgaaaa aacttgtttt gtcacactgg
     1261 ctcatccgaa gtacaccaaa ccccagaaag gaaataaaac agatcgcaaa gatgcaaaaa
     1321 tggatttgtg atctctttat gtgcgacatg atcaaaccca gttttattcc tggtcttgaa
     1381 atccgccagc ttcgtgatct aatgcgttat cggacgaaac tgaccaacat gaaaacaagt
     1441 gaaaagaatc gtgctttaaa ctgcttaacc gtttctaatc tgaaactaga tgatgttttt
     1501 agtgatgtgt tcggaaaatc atccacttct atcatccaat acttgttaga acatcccggt
     1561 gaatcatttg atgttcgacc atttatccat gcccgttgta aaactcccgt tgaagaaatc
     1621 caagcggcag ttgagggggc gatttctgta cctcaagcga ttaagcttcg ccaatgcctc
     1681 aaccatatta acgagattga gaagcatcga gaagagatca atctagagat tcaagctctt
     1741 gcagaaccct tctcccctgt tttggaacta cttcgtacca taccgggctt agacactcag
     1801 ccaataacag cgattgcgat tctttcagaa ataggaccgg atatgtccgt gtttccaact
     1861 tcgaaacact ttatttcttg ggctggatgc tgtccaagaa acgatcgcag tgcccgacga
     1921 acaaaatcaa cacgtatctc tcgtgcaggg cagtcgttga aaccgctact tgtacagatt
     1981 gccaatgctc ttctcagatc caaagaacat ccagaattta aaaatcgcta tcgtagaatc
     2041 aaagcgaatc gtggacacaa gaaagctatc attgctattt gtaagatgct cctgaccgct
     2101 atctggaatg tcttatcaaa ggtggaaccc tattctgcta aaggatatct ggagccaaaa
     2161 cctgcgaaag aagagaaagt tctgacgcaa tcccaagctc tggacctttt aagaaaacgc
     2221 ggatatacca ttatagatag tgcttaaacc aaagttacgt tgattcttcc taaatagact
     2281 cgttgtcttc catttcaaaa attttgaaaa cggtaggctt atttagtgta ccgttcttca
     2341 ggtatcttca aatagattta ttttcaaact tatttccttt cttcttttac tctcctatag
     2401 cttagcattt aagtgggcac tcgtgtcacc ttgctagata gctatgaatg ccgtaataag
     2461 cctcctagta tataggcaga ctgccaatta taactgattc aatccacatt atgataaaat
     2521 ccaccttttc gtttcatatg tgttgaaata tcacatatgt caaaagtgca cgagtctttt
     2581 cattcagtgc tttgtaaata ctcaaaatta ttccttttca ctttaaaaaa aagataatta
     2641 gtacaaaatc agaaatgagg aaagtattag gatggactag aaaggagttg ttgaatttgt
     2701 tgcaacagat tggtcattta tcaattaaaa attaggtgaa gttttattca tcactgcagc
     2761 tgctgtttcc cagagaataa aacgtctaga agaaactggt cagttactgt attatcaagc
     2821 agcaattgac tacgaacaag cttgattact aaccaaagcg tttatccacc tgttgattaa
     2881 atcaaatcaa aaatcaggtt tttatacgtt cataaaagca atctccagtg tactcgaatg
     2941 tgactgtatc ataggtcctt attcgatgtt aatcaaaatg gggtttcctt ctaccgaatc
     3001 attggacagt tttatcaatg atttatcaaa gtttggacga accaacaccc aaatcgtttt
     3061 ctcgactctt gtttccttaa tggtttatca gttctggaat gtttatcatg cgcttttatt
     3121 aaaatagaaa agagcttttt tcatgcgaca aagcagtgat catttattgg cacatgcaat
     3181 ctttgtggat ccattttttg aaaatacgat atttagtttt gacccaaaaa tctttaaata
     3241 cgtatttgat aatttatctt aacaaccaga taattttatt cagcaccgta ttatctatat
     3301 tgaattctcg gaatcaagat aaattttttt ccgtttttgt ttctttttta atcttcttct
     3361 tgttattaat agtgattagg atgatattcc tatattgatc tttgataatt agatataatt
     3421 tttgaataac gttccctgct attcgagcta gaaatacaag tacgccatga cctagttagc
     3481 gacaactact tagagatttc ttttgttctg ggacaacaaa atgccatgac aatagcagta
//
LOCUS       DACBYO010000168         3416 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.171, whole genome shotgun sequence.
ACCESSION   DACBYO010000168 DACBYO010000000
VERSION     DACBYO010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.171"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            314..2233
                     /gene="tet(M)"
                     /locus_tag="IVD26_002888"
     CDS             314..2233
                     /gene="tet(M)"
                     /locus_tag="IVD26_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAP6080789.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2352..2519
                     /locus_tag="IVD26_002889"
     CDS             2352..2519
                     /locus_tag="IVD26_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6080790.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(2579..2932)
                     /locus_tag="IVD26_002890"
     CDS             complement(2579..2932)
                     /locus_tag="IVD26_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6080791.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
BASE COUNT         1164 a          523 c          652 g         1077 t
ORIGIN      
        1 caatttgatt tggtacttga aaagaacggg agtaattgga agattataga ataacaaata
       61 ttggtacatt attacagcta ttttgtaatc acgtactctc tttgataaaa aattggagat
      121 tcctttacaa atatgctctt acgtgctatt atttaagtat ctatttaaaa ggagttaata
      181 aatatgcggc aaggtattct taaataaact gtcaatttga tagtgggaac aaataattgg
      241 atgtcctttt ttaggagggc ttagtttttt gtacccatat gcccttttgg gtttttgaat
      301 ggaggaaaat cacatgaaaa ttattaatat tggagtttta gctcatgttg atgcaggaaa
      361 aactacctta acagaaagct tattatataa cagtggagcg attacagaat taggaagcgt
      421 ggacaaaggt acaacgagga cggataatac gcttttagaa cgtcagagag gaattacaat
      481 tcagacagga ataacctctt ttcagtggga aaatacgaag gtgaacatca tagacacgcc
      541 aggacatatg gatttcttag cagaagtata tcgttcatta tcagttttag atggggcaat
      601 tctactgatt tctgcaaaag atggcgtaca agcacaaact cgtatattat ttcatgcact
      661 taggaaaatg gggattccca caatcttttt tatcaataag attgaccaaa atggaattga
      721 tttatcaacg gtttatcagg atattaaaga gaaactttct gccgaaattg taatcaaaca
      781 gaaggtagaa ctgtatccta atatgtgtgt gacgaacttt accgaatctg aacaatggga
      841 tacggtaata gagggaaacg atgacctttt agagaaatat atgtccggta aatcattaga
      901 agcattggaa ctcgaacaag aggaaagcat aagatttcag aattgttctc tgttccctct
      961 ttatcatgga agtgcaaaaa gtaatatagg gattgataac cttatagaag ttattactaa
     1021 taaattttat tcatcaacac atcgaggtcc gtctgaactt tgcggaaatg ttttcaaaat
     1081 tgaatataca aaaaaaagac aacgtcttgc atatatacgc ctttatagtg gagtactaca
     1141 tttacgagat tcggttagag tatcagaaaa agaaaaaata aaagttacag aaatgtatac
     1201 ttcaataaat ggtgaattat gtaagattga tagagcttat tctggagaaa ttgttatttt
     1261 gcaaaatgag tttttgaagt taaatagtgt tcttggagat acaaaactat tgccacagag
     1321 aaaaaagatt gaaaatccgc accctctact acaaacaact gttgaaccga gtaaacctga
     1381 acagagagaa atgttgcttg atgccctttt ggaaatctca gatagtgatc cgcttctacg
     1441 atattacgtg gattctacga cacatgaaat tatactttct ttcttaggga aagtacaaat
     1501 ggaagtgatt agtgcactgt tgcaagaaaa gtatcatgtg gagatagaac taaaagagcc
     1561 tacagtcatt tatatggaga gaccgttaaa aaatgcagaa tataccattc acatcgaagt
     1621 gccgccaaat cctttctggg cttccattgg tttatctgta tcaccgcttc cgttgggaag
     1681 tggaatgcag tatgagagct cggtttctct tggatactta aatcaatcgt ttcaaaatgc
     1741 agttatggag gggatacgct atggctgtga acaaggattg tatggttgga atgtgacgga
     1801 ctgtaaaatc tgttttaagt atggcttata ctatagccct gttagtaccc cagcagattt
     1861 tcggatgctt gctcctattg tattggaaca agtcttaaaa aaagctggaa cagaattgtt
     1921 agagccatat cttagtttta aaatttatgc gccacaggaa tatctttcac gagcatacaa
     1981 cgatgctcct aaatattgtg cgaacatcgt agacactcaa ttgaaaaata atgaggtcat
     2041 tcttagtgga gaaatccctg ctcggtgtat tcaagaatat cgtagtgatt taactttctt
     2101 tacaaatgga cgtagtgttt gtttaacaga gttaaaaggg taccatgtta ctaccggtga
     2161 acctgtttgc cagccccgtc gtccaaatag tcggatagat aaagtacgat atatgttcaa
     2221 taaaataact tagtgtattt tatgttgtta tataaatatg gtttcttgtt aaataagatg
     2281 aaatattttt taataaagat ttgaattaaa gtgtaaagga ggagatagtt attataaact
     2341 acaagtggat attgtgtcct gtatgtggaa ataaaacacg attaaagata agggaagata
     2401 ctgaattaaa aaaattcccc ctctattgtc cgaaatgcag acaagaaaat ttaattgaaa
     2461 taaagcagtt caaagtaact gtgattacag agccagacgc aaagacgcag agccgataaa
     2521 atgagattaa tacaatctca ttttatcggc tctttccgtt atgtatggat tcttttaatt
     2581 agtcttcgat gtttcttgct tcgttgatac cgctggctaa agattccatt aaggatagtt
     2641 ctttgtctgt aaagctatcc atgtatttct ctatctgtaa tcgtcgggtg ctttttacca
     2701 agttattagc aggtaagaaa aattcatcaa cggaaacatg aagtaacgat acaaggtcat
     2761 aaagaacttg tatgctgggg tgttgccctt tattttcaat attagttaag taccgtgggt
     2821 caatttcaat caatgctccc acttgttcac gagttaaacc tcgtttcaat cgagcttctt
     2881 taatggctaa accaaaggct ctaaaatcat atttatcttc ttttttacgc atagtagacc
     2941 acctctatac attttattgt tcctactgaa ttaaaaacag gtatagaaaa acgtgttata
     3001 tggtttatag gtttatattt aataaaaagc actactaaac gccaataaaa aaaaccgtta
     3061 tatggtagtg ctatttacgc tgttaaaata ttgtatatta cttccaaatg gcggtttgtt
     3121 ggaggtcaac gtcgccatga agtacatcat atacaataaa tttccttaca ttgggttctt
     3181 gtcaaaaaaa gtcgtctatc tgcaatagat aagtacgtcc accaatgtgg ttttataaat
     3241 catatagata gaataacaga agcatgtaaa cagagaaata aatctgttta tatgcttttt
     3301 tggctattca gaactttttt acaaagttta tttatcagta atgcaacaaa tccccctttc
     3361 acattgggac taagagtgaa aggagataaa cgagcaaggc tcacttcctt tcctag
//
LOCUS       DACBYO010000169         3399 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.172, whole genome shotgun sequence.
ACCESSION   DACBYO010000169 DACBYO010000000
VERSION     DACBYO010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.172"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..276
                     /locus_tag="IVD26_002891"
     CDS             <1..276
                     /locus_tag="IVD26_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HAP6080792.1"
                     /translation="ELIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERIN
                     ELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
     gene            419..640
                     /locus_tag="IVD26_002892"
     CDS             419..640
                     /locus_tag="IVD26_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014315041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6080793.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            656..1498
                     /locus_tag="IVD26_002893"
     CDS             656..1498
                     /locus_tag="IVD26_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080794.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1561..3363
                     /locus_tag="IVD26_002894"
     CDS             1561..3363
                     /locus_tag="IVD26_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HAP6080795.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
BASE COUNT         1229 a          469 c          703 g          998 t
ORIGIN      
        1 gaactcatca agctggctaa taagggtcaa gattatgaac atctagcaga tgagattgat
       61 gagctgagag acaagcgaca gctcctttta gtagaagatg cctccctcag tggcgagaac
      121 gagcgaatca atgagctgat tgaatttatc cgcaagaaca aattccgtac cttagagtac
      181 gatgataagc ttgtaaggaa gataatccag agcgttacag tctatgaaga acacttcgtc
      241 atatccttca aatctggcat cgaaatggaa atatgaaaac cagaagtaaa tagcccatga
      301 ttctacagta gagtcgtggg ttttcttttg cttgctgatt ataataatat tttaataact
      361 attgttatta taaaccaaat gatttataat attcttagcg taaacttgga ggtgctgtat
      421 gactacggca gaaatgatta aagaactgtg tgagcaaatg aatataagtg tttccgaact
      481 tgctagacgt attggacaga ctccacagaa tttcaataag aaattacaac gagaaacggt
      541 aaccttagat gagttgaaag cgattgctga tgtgctaggt gtcaagtttg tgcaggcttt
      601 tatattgcct gatggcaatg aaataaagat aggtaattag gaggtgtaat ttgtattgaa
      661 aatcataaca ataaatgatg ttgagtatgc tgtatttgct gctaatgaag gtacttccaa
      721 accacaacct catatcatag aaacgaaatc tggtactatt ccagaaggaa aacaactgag
      781 tttattaaaa gaatatctta agcagaatga tatttcccca ataaaaggag caacaacata
      841 ttggtgcatt gacaaggttc ttaagcttga ttcaagtaaa gaaaaaacta taagtgaaac
      901 aatccataaa caaaaatact tatctttaac tgaagaaaat attgagaaac agcataagtt
      961 tgtaggtgca agctctaatt atgggaaaga aggtctaata atacatgatg ttttgaatgc
     1021 atttcctctt cataatgatt taaatactat tgcgatgaag attgcggtaa ttgatgtaac
     1081 aaattcaaca catctttctc aatataagag caggttgtct ctatatgatt tggctaaagt
     1141 aattctggag attccaaatt ttgatgatcg gttggcaaaa ggagatcctc agttgataaa
     1201 tattatcgca aggaacattg gtgcagttaa tatgttctca tttgcatcca agtactgtac
     1261 atatcataat gtggaagtgt gtgggagaga tgattactcc atctttgatg gtatcgttaa
     1321 aaatactctt ccacactata tccaaggact aactacgaat aagattgata cgtggcgaag
     1381 aagttttgat tacgaggcat ttaacgaatg tgttggaaaa ctacttgatg aaaataatat
     1441 acatattcct tttagaagaa gaaagttaga tcacttcttg tggtatgcga ataggtagaa
     1501 tataagaaaa aggcatcgta aaagtgattc tggataaaat taatggggga ggaaataata
     1561 gtgggattat ttgattttct aaagaaaaaa caaggaaagg ttagtaaaca cgttgattat
     1621 caactggctt ctagtctatt tcgtactggt aaagtttttg ctgaaaaatt ggaagtggac
     1681 atatcaaatg tagatgagtt tcgtaaaact tttatcgctt ttgatgtgga aacaactggc
     1741 ctaaattctt cttcagatag aattgtagag attggtgcgg tgctatttaa agaaggagtt
     1801 ccaattcaat cattcggaac tcttgtcaat ccaaaagtta gaattgcagc ctcagcttcg
     1861 gcaataaata atataactaa tgaaatgcta aactctgctc caaatgagca ggaagtttac
     1921 ccccagttgg tagaattttt aggagatgca ctagatggaa aaatcactat gtgtgcacac
     1981 aatgcaagtt tcgattttgg atttttaagt aacacatttt ctagacttgg gtatgatgct
     2041 aaaattaagt atgttgatac tctgagtctc tctagaaaac atataaaagg cattgtaaat
     2101 cataagcaag agactgtagc ggaatatttc ggattaataa atgacactgc ccatagagcg
     2161 gaatcagatg cagatatatg cggaaagatt ttttggggtg ttttagatat tattgaggag
     2221 tcgttggaag aacaaaaaaa gcaaatagaa aagatgactc cagacataaa agaacttgaa
     2281 gcttgtgctt ttattcaaga tattattgag aaaaaaggat gcgacaccag ttggatcagg
     2341 tatcgaaaaa acagtaataa ttatgtcgat gtaacttgtc tatatacatt cttaaagttt
     2401 aagtttgcta agaagggaaa ttacatcatt attagaaaag atgctacaaa tggaattgat
     2461 ttacctatag aaccttgtac tgtaagtgaa ggcggtacaa caaatgtgcg agtctatttt
     2521 cgtagcccct ttgacttaac gcctctttca aattatattt tcagtgctta tagcgattgt
     2581 tataattcta tgaatgaata tatgagtgtt agtaattaca ctaaaaaaga agcagagcaa
     2641 agccttagta tgctgaaatc tatttcaaaa tcagcgatga aagagttatt attcgatgca
     2701 aaaaatcgtg gatatgatga gactgaagtt aacctaaata ttgaaaaagt gatatctaga
     2761 gaagatgtaa ttattaacgg gttgcataat cgagtttcat taaacaagat acgaaatata
     2821 gggaattggg agaaaggatt tgatgcaggt tatccatatt gggaacgtgg agaaactgct
     2881 aggaaaaatg gcaaagtaga tgaagctatt gcactttttg ataaagctcg atataacggc
     2941 tatgatgctc ctgcgctata tgattcttat gctaaagctt atcgaaaaat taaggattac
     3001 gataatgaaa ttctcattct tgatgaagga attatgcgta aaacacggca cgatgttggt
     3061 actttagagg ctcgtaggga taaggcaatt aagctattat ttgctaaaca agaggcagag
     3121 cggatagcta aggaaaaatc tgattttcta aaagcgaaca aaaaagagga tgcgattagt
     3181 gagcctagca agaagcgtgg aagacagatt attcaaatga ctgatgatgg aacaataata
     3241 aaagaattcg atactatagc ttctgctgta aaagaagttg gcgttaactc aaaaagtatt
     3301 agggatgctg caaatggagt tcaaaaacat gctggaggat actactggaa atacaaagat
     3361 tagcagataa tctaagataa cctaggatct tcttaatag
//
LOCUS       DACBYO010000170         3389 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.173, whole genome shotgun sequence.
ACCESSION   DACBYO010000170 DACBYO010000000
VERSION     DACBYO010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.173"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..2303)
                     /locus_tag="IVD26_002895"
     CDS             complement(<1..2303)
                     /locus_tag="IVD26_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080796.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVET"
     gene            complement(2975..3243)
                     /locus_tag="IVD26_002896"
                     /pseudo
     CDS             complement(2975..3243)
                     /locus_tag="IVD26_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          921 a          763 c          548 g         1157 t
ORIGIN      
        1 gtttctacca gctgatatgc tcctggtgct aaaccgtcaa ttgccagttt tccatcttct
       61 cctgtagtta aaccggtttg tagcgtttct ccttctcggt tctgtaactc aaaaacagct
      121 ccttgaagga cttcaccact gccttcagca tgtttaatta gttcaacacc acccgtatca
      181 aggatgtttt caatggttaa cgtcacttct tctatggagt attcatttat aaaaacatca
      241 tgtaccgtcg catctaaaag atacccttcc ggtgcttctg tttctcggac ttgatagcta
      301 cctacaggaa gcggttcact taaaaattct ccgttttctg ccgttatacc ttcttgtatc
      361 acttgtgaat cgcttgataa aatttcaaat tttgctcctg ccagcctttg gccattctca
      421 tcagttttaa ttactttaat acgcccatcg attttccttg ttcttacagt actcgtattc
      481 aatcgattgt cactattcac aagcgttgca aagtttaaaa tttgatcgcc gaccgcatac
      541 gcctctacat tgaccttaaa agagagggta aaacttgtcg gaccaccaat cgtattattc
      601 gcactgaaac gaactattcc attattgact tcggcatcaa tgaaagaggg aatatctgat
      661 agaaatgaca caaattccat gccttcttcc aaaacatctt caataacaag cgtatttctt
      721 gttccagaaa acatcgagac atgcagagta tacgttagtt cattttcatt gagattgata
      781 acatttttgt ccacactttt tcttaaagag attgccggaa gattactttc agggattctc
      841 aagcggtagt ctcggctcat tacctgatta ttgtaggtca tactcgctcg attccgagaa
      901 aacccatcct cttgtcttcc ttcattgaac aagtcgacat cggtcacttc aagagcatat
      961 tcaataaaat acgattgacc ctctgctaga ttaccaaagt ccacaacaag tgtattcgtt
     1021 tccttattaa aagatacttt gtccacaaat tcctcggaaa cataatgagt tctaacgttt
     1081 gcttcacctg gattcgttac ttctgcgatc cgaaccccac ctgaaatagg ttctctattt
     1141 ccagtggaac tccatgtagt cggattcggt gccaaagttg ttccttgcgg tagtacatcg
     1201 gtaaccacta caccgtcttt tcgtgatcct tcataattta cctgcaaaat aaatttatta
     1261 ctgttggtca cgtcttgccc gtcaatcagc agattcccaa gatttccttg gctgtcgatt
     1321 tctctagagc catagtataa tttcgaaaaa atgggtcttg atgaaggaat aggcgtaatt
     1381 gaaaattccg tgtttgctgc tcgctcagca taagtaagac tcacttgaaa gtcattattt
     1441 ggctcagtac cgcctgattg aaagaaagca acttcaaacg tgatactgaa tgtatacgac
     1501 tgagcggctt catttaatcc ttcataatca aaggtaaatg gaaaaacaac gtctgtgcct
     1561 tcttggtaaa atgccagtgg ctttaaaggt gaatcatcag cgacctccac tctaatgaac
     1621 tcaattaagc caatcgatgc tctaggaact cgtacgacca tctccccata ttcttcaaga
     1681 atatcgccag cgcctccttg aatgtatccc tttaacgttt gtgtatgcct gctcggcaaa
     1741 gtggggcgct cagcagagat gccgatgtca taattcaaga gctcctcttg tctttcaatc
     1801 tgagattcct gcgttataga tggctcagat gatctggctt cattaaaaga ttcacttaag
     1861 ctttcttctg gtatattaaa agattcactt gtgctttctt ctggtacatt aaaagactca
     1921 cttgtgcttt cttctggtac actgatttct attgagaccg tatttgattg aatatcaccg
     1981 cttcttgcgg tcaattcgta tttacctgaa tgctgggaag aataagtaat cagacgttcg
     2041 taatcattga gttgcttcac ttccccttca atcaaatcct cactcttatc aatgaccaat
     2101 gcatttagca ggtctggtgt tcctctgact cgcaactgga actgctcacc caaagcagcc
     2161 tcctcttgat caacttcgat cgtcagcgaa cgctctggct gttctgctaa agactcagct
     2221 agaaccgtta tgttcccaaa ttgattgatc acaataagca taactagaaa catacttaac
     2281 agtttatgaa atttgttcct cactattact cccccttata attttgacta aacaacaagg
     2341 tacccgataa ttttctaaaa agattcccca actcaaaatg gctgcgttac ctccctcgta
     2401 ttttcggttc aactcaagcg ttgcaatgta agctgtaaac aaagctaatg attgccgatt
     2461 gtcttctgtt gattgattcg atagctttgt atgactttta gttgtccgtg tggcttaacc
     2521 ataattatga tttcacgatt cctcctgcca gtgccttgca caagctggag cgtaacccta
     2581 atagttattt tgttaatgta cttatatact tttatacttt tccattagaa acaatcacta
     2641 aatcgttgat accaaggtca gactctagaa tttcatcagt gagtccctgt attggttaac
     2701 cttcatcaat cccaaaaaaa tatatcaatg cttagcatca aaatgaatat atagtttaga
     2761 atacttggga ttcatcgata actgatcgct tatttggcca tattatttgg cacttggttc
     2821 aactaaacgc atttaggatg ttccttcatt ctcgtcatgg atgttctcaa accgtcatta
     2881 ctaataaact gtccaccgaa tcgatggttc atttcttgca ttttccacgt ccaattactc
     2941 tttttgctct ttatttgggc gtagtttcac tttcttaact tgtatcgtct tccatcaact
     3001 ccttaatcat cttcttagct ttattggctc ggtttccttg taaaaggtat ctacaaatag
     3061 tgacaatctg tattaaatct tcatcatttt ctgtaatgtc aataatttct atattctgta
     3121 ccatatattg caaagggttt cactaagttc ataaccgaag cgaattaaac aacttttgta
     3181 tagaataact accttttcta tttttccatt ggtaattcta tctattaatt ggtttaatcc
     3241 ttttgttgta gttgattcca ctaccaagat gattctctcg aattttaaag cttgaagatg
     3301 tattgctatt tttgctaact ggcgtatttg caactatttt tcccttctat tcttccttca
     3361 ttgattcccc tctaaaatta ctatccata
//
LOCUS       DACBYO010000171         3318 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.174, whole genome shotgun sequence.
ACCESSION   DACBYO010000171 DACBYO010000000
VERSION     DACBYO010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.174"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            380..1015
                     /locus_tag="IVD26_002897"
     CDS             380..1015
                     /locus_tag="IVD26_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6080797.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            1151..1243
                     /locus_tag="IVD26_002898"
                     /pseudo
     CDS             1151..1243
                     /locus_tag="IVD26_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            1357..1992
                     /locus_tag="IVD26_002899"
     CDS             1357..1992
                     /locus_tag="IVD26_002899"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP6080798.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            2099..>3318
                     /locus_tag="IVD26_002900"
     CDS             2099..>3318
                     /locus_tag="IVD26_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004081244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6080799.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRI"
BASE COUNT         1103 a          500 c          623 g         1092 t
ORIGIN      
        1 tttgtgaaat agtgcccccc tgttagataa cgggggcaca gacaaggctc gcaggctcgc
       61 cagccgacaa agcatttctt ccccttgaca caaggtgtca tggcggtaag cctgagaggc
      121 ttccgccacc gtgtcagaaa tactttgtca gcaagttctg ttttgccttt tctaacaagt
      181 tccatttcaa ccgatattca tatctacgga tttaatcaga taggtatttc tttttgaatg
      241 tttttatatt tcattctatt gtgcttattc gattacaaga acatagtaat tcttatatgc
      301 ttatttgtca atatcttttt ttgcctttac aaatcatatt aagcatgata gacttataat
      361 agcgaagata taacgagata tggagggtta tgcaatgaaa ataagccatt taggaaataa
      421 tatacagacc ataagaaaat ttaggggaat gaaacaacag gaacttgcgg acaaaatcgg
      481 tatcaatatg cagagccttt ccaagattga aagagggttg aactatcctg cctatgaaac
      541 gctggaaaag ataatggaag tgctggacgt tacgcccaat gaattgttgt cgggagaatg
      601 gaagtatgtc aatcaatctg aaaaggaagt ctgtcagttt ttaagagccg aagaacgtct
      661 aaatgcagaa ctgaaacatg gacactatga taacttcttt gacagcgagg aagaatggct
      721 ggaatatgag ttagaaaagt tacgggaata tattacagac tatatcaacg ggaaaagcat
      781 tgaagcgtcc gacctttacc caatcaaaga atttatccag catttgaagt ttcaaaaatt
      841 attagaccgc tatgatgatt tatacagtat ggatatgttt ggggaaagca tagagggaca
      901 taagtataag acaccttatc aagtcgtgaa aatgataaac ccgaactcaa aagaagatat
      961 ggaactgtta cgagaagtat taaggaataa caattttgat gatgaggacg agtaactttt
     1021 ttcctcttgc gagaagatac agcaaacaaa aagcccgatc aagagtgcaa agcaccacca
     1081 atggtggcaa agctcttgac agggcttttt cttttctgtt gtgggcaatc aagaggaaga
     1141 aagggataaa atctgatttg tggtaaatca ggcaaaggca acgcaggtat cacagtatga
     1201 attgacaccg cataaggaaa gcaactggaa gattgtagaa taaatgaaaa aggcttgcat
     1261 tctgcatttt tataaaattg caagtcttta tattgacaag cataaaatac taagatatac
     1321 tttaatcaga ccaacggttt gtattggagg taagttatgg cacgaaataa atatccagaa
     1381 gaaacagtaa aactcatttt agatgtttct acaaaaatgt tttgtgaaaa aggatatgat
     1441 aacacatcat tgcaagatat tatcaatgaa acaaaacttt ctaaaggtgc tatttatcat
     1501 catttcgatt caaaggaaga tattttaaaa gcaatttttc aaagaattgg aaatgaaaat
     1561 gcagtaatat ttgctaaaat tagagataac gatagtttaa acggtttaga aaagttaaga
     1621 gaaatattta agacagcggt attcaattct aaccaaagcg ttttattgac agtttctcct
     1681 caactattaa acaatcctcg ttttcttgct atgcaaatag aacaaatgta tgaaattgta
     1741 gtacctgaat ttgttgaacc cgttttagaa caaggtatca aggataagtc tttggagatt
     1801 gaaaattcac atgaaattgc agaagttatc atggtattaa gtaatgtatg gctcaaccca
     1861 ttagttgaaa tgacggataa agagggtatg gaaaaacgtt gcaatacatt caatgccctt
     1921 ttaaatggaa taggcataga cacattatta gacgaagaaa caatttctgc atttatacag
     1981 ttttgtaaat aactgtattt gttatcccta tacgatagac tgctctataa aagagcagtt
     2041 tatttaaacc attatataaa ccgacggtct gtttgattaa ataaaaagga gagattttat
     2101 gcaagcagaa aaaaaacttt ttaatcgtga ttttatactt gttgttatag gacagataat
     2161 ttctttattt ggaaacgcta tcctacgatt tgcattaccg tactatttgt taaaagaaac
     2221 tggttcatca gctttgtttg gtattgctac agcctgctct tttttaccta tggttatttt
     2281 gtcgctggta ggtggtatta ttgctgacag gacaaataaa agaaacatta tggtcatact
     2341 agattttgta acagcaatca taattttagt attttatttg tcattgggaa aaattcctat
     2401 catacctttg tttattgttg ctttgatgtt actttatggt atttctggtg catatcaacc
     2461 agcggtacaa gcaagtattc ctctattggt atcatcagat aaacttaccg tcggtaatgc
     2521 tataataaat caagtaaata ctttagcaaa ctttatcgga ccagctataa gcggagtagt
     2581 ttttcaattt tatggtatca atcccatttt aattgttagt attatatgtt ttactttttc
     2641 agccattatg gaaattttta tccatattcc acaccaaaaa agacctcgtg aagtaggtgt
     2701 aattgcagtt gctaaaaacg atttaaaaga tagttatacc tttttgaaaa aggagaaacc
     2761 catttttata tccgtaatct ttttggtttg cattttcaat ttggttttaa gtgctgtttt
     2821 aattgttggt ctgcctatct taatttctga agttttaaaa atgccagata cactatatgg
     2881 tttttcacaa tcagcattat cattaggtgg tttatgtggt ggtattttaa cagctcttgt
     2941 tgcttcaaag ttaaaactaa aaaaccttta taccttgtta cttatttgtt ctgtttctgt
     3001 tttacttatg ggaatttcgc tatttttaga attgcctgca atagtttcct actgggtagt
     3061 tacagtgatg tgctttgtgg ctatgggtgt atctactatg tttgttgttc aaatttacac
     3121 tcttgttcag acacaaacac caccgcaatt agtaggaaag ataatggcta cgctggtagc
     3181 agttgctatg tgcggtcaac ctattggaca aatggtttac ggtattttat tcgatgtatt
     3241 tatacaagaa acatgggttg ttatgtttgt agcttctatt gcttcaatca tgatttcaat
     3301 atattcaaaa agaatttt
//
LOCUS       DACBYO010000172         3264 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.175, whole genome shotgun sequence.
ACCESSION   DACBYO010000172 DACBYO010000000
VERSION     DACBYO010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.175"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            889..1101
                     /locus_tag="IVD26_002901"
     CDS             889..1101
                     /locus_tag="IVD26_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080800.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(1379..3178)
                     /locus_tag="IVD26_002902"
     CDS             complement(1379..3178)
                     /locus_tag="IVD26_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP6080801.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         1154 a          565 c          567 g          978 t
ORIGIN      
        1 tttttttcat gaaagatctc cttttttatt tttattatat taaatattat acagataata
       61 acggaatatt atcatcgaaa cagctaacaa aattgtcata aaaaacgaga tggttgatat
      121 tagaacttgt gtttttgttt aggtctagag ataaagagag acaatttcca aatatatgta
      181 atgaatacaa aaagacgttt gtcgcggatt accgttacaa acgtctttta ttgattttcc
      241 gagatctcat cagtcgccat ttggaatggt tcactcctta tctagattcg tttaatgctc
      301 ggactgcttg ttcgattgta ataccaaacg caacgttatt ttcgttttgt gcatcaatcg
      361 ccataaaacg gttagaagtt gtatcaaaag ctacgcggta ttgcatattt gtttttgtaa
      421 acgtcataaa attcatctcc tttgtaatgt aatttagttc ttgaaagttt cctttaaact
      481 ttcgaactta taccaagttt agcatcgtac gttttttgat gcaattaaaa agcatttatc
      541 attttcctta tttatttttt cttaaatggt ttagctattt tcttttaatc cgataagtag
      601 cccaatcatc aaggttacaa atactattgc ttgaatataa atcatatgct cacctcttta
      661 taaataactt agcaatataa agaaaaaaac gcacgaacaa cataggaata taaacaaacg
      721 tttttgtcac aacgtctaag atcgtgttaa aaaatagtta tctaaaaagc agaaagatac
      781 tcaaaataaa aaataaaaaa atgaataaaa acgttttcaa atacaaggta atttgttatt
      841 ataaaataaa gaaaaaacaa aataaaaata aagaaaagag ggaatgaaat ggtaaaagca
      901 gaagtaggaa gatcttatat atgcaaaccg atcggagtat ctcatgaact aatcggctgt
      961 attgaacgta catatatcaa cacggctgtc gtgtatgttg aaagttatga ccaacgagac
     1021 tatcaactta tcaatgaaag caagtatcgc atgctcgtaa aattctgtga tattagcgca
     1081 cctactgaat tggtttctta aacagtattt ttgagaattc gcaagaactc ccttataata
     1141 taaataaaga cagaagggag cgagaagata tgccaaaaag aaaaagttca gggaaaatgg
     1201 gaattattct tgcagtgatc tctgcaattc ctgctatttt agctattgtt cgtgcgatga
     1261 aggaatcaag agaaagttaa gcacacatta tgagcgtcaa acaaaaaacg catatacctg
     1321 cggtggcagg ttatgcgttt tttgttgtat aaagactttt ttcattaacg atttttgatt
     1381 agccgactcc caaaacaaaa tttagcagtt tatctgaata agtgatttct tcatctgttt
     1441 gtttcacact ttcatttagt agtcccatct catcggttat gataccatcc acaccataaa
     1501 acatcatgcg actcatggca tctgaatcgt tgattgtcca tacatatact tcttttccgt
     1561 cttggtgggc agaattaatg aagttacggt tgatcgtact atattccatt gtcagaaaat
     1621 cagcaggcgt cacagggggc ccaacaatat tgaaaggtaa gatgtagccc acataaaagt
     1681 ttggttctgc ttcttttaaa tctgaaacgg tttggtacgt caaactttgc aaaatatgat
     1741 ggttctctaa gataactttg cggtatttat ggacaaatcg ttcgacaagg tcatccgaat
     1801 cttttttaga ggtcttgatc tcaataagta atttttggtt tagcttatgt gctttttcca
     1861 aataagaatc aaaagaacaa acaggggctt gcactccgtt ttcagtaact gtaagatttg
     1921 tcaattcttt caatgtaaga tcctgtggtg ttccatttac ccctgttaag tgacgaagat
     1981 ttgcatcatg catcactacg aaatgaccat cttttgtttc ctgaacatcc atctctacat
     2041 aatcaggatg atagtctctg cttgtttttt caagtgcttc taaagtattt tgcgccccat
     2101 tttgggtact cacacctctg tgagagacag tcactggttt tgtctgaaca gctgaagtca
     2161 gataatccat attgtaaaga cagacgccaa taccgaaaaa aactgcaaaa agagtcaaac
     2221 cagtgttttt cagcgcagag aaacgcaagt tgggggcttg tgggataaac cacttaggga
     2281 tctcaggcaa gaagccttcg tcatccatga aatcaacaat gatataaaaa atccctacgg
     2341 tagacatcac gatattgaat aataaaatcc cttgtaaaag cgtcatagca aacacagcgc
     2401 tgatcaatgc atagtctggg aaaaattgtt caaccatact ttgtgccaaa ataacaacga
     2461 tatatcctaa agaagaaagg agtaaaatcg taccgccaat cacaataaat tggcccgtga
     2521 tggccaaaag acgcgatttg gtcaatgacc agctttcccg aatggctgct cgaaaagaac
     2581 gatctcgtag aatcatttcc ggtaaagcaa aaatcagtcg aatcccaata tagccaagga
     2641 aaatataaac gagtaaaaag gaactgacga tgatccaacg attagcaaaa ataaaatcca
     2701 taatgaaagc ggggattttt atttttgaca gtagatcaga attaaaactt aatccgctga
     2761 tcggtagaat caataaaaaa taagcaagga aaaacaaaaa agtaatgggt ctcactttct
     2821 tcagctgaag tatcgtcaag tgtaagagtt gcttcaaaga gattggttct ttctttttaa
     2881 taaaaaaaac actcatcaaa agaaaagtaa attcgaaata aactaacagt aaaatcgtca
     2941 tcaaaactac gattaacgag agtagaaccc caggatgttg agaaaaaatt gaaggaatat
     3001 tgtcataaga caaatagtca attgcccctc ggtgtaaaat aaaacgggtc gtactgctca
     3061 ataagggtaa acaaataaat aaaataaagc catgcatcag caagacatca cggaaataag
     3121 cttgtgttcc ttttaaaaag tcccaagcat tacctaagct acgtttcaaa taattcatcc
     3181 tatcacctgc tcttcacatt gtagcgcaaa tctaatgaaa aaggaaaggg tgcagtgtgt
     3241 tttgcagacc ctttcccaga ttta
//
LOCUS       DACBYO010000173         3221 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.176, whole genome shotgun sequence.
ACCESSION   DACBYO010000173 DACBYO010000000
VERSION     DACBYO010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.176"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            301..585
                     /locus_tag="IVD26_002903"
     CDS             301..585
                     /locus_tag="IVD26_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080802.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="IVD26_002904"
     CDS             588..1004
                     /locus_tag="IVD26_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080803.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="IVD26_002905"
     CDS             complement(1141..1860)
                     /locus_tag="IVD26_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP6080804.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2535..2630
                     /locus_tag="IVD26_002906"
     CDS             2535..2630
                     /locus_tag="IVD26_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAP6080805.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2932..3177)
                     /locus_tag="IVD26_002907"
     CDS             complement(2932..3177)
                     /locus_tag="IVD26_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080806.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1074 a          599 c          503 g         1045 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtactc
     2041 agataaaaag ttgttagtac ccttctgtat ccgttgggag agtaaggctc aactgccccc
     2101 taaaaagggt tctaaaaaat ctttaaaaaa taaataaaat aaacgcgcgc gcgcgagcaa
     2161 aatttcccgc caaaaaatca cccacttttt aaaataaaca ggttcgcgca tgatattaaa
     2221 ctgccaatct agctccctat ggtcgctgta agaaggagtg atcgctacgc tctcacattt
     2281 tacttgcagc agtcgccttt aggctccttc gccaaaaata attcattagg gactcctttg
     2341 tggcgtcctg agagctcgtc taagccgttc taagacaaga ttcgataaaa actatgtcct
     2401 tcgttctaaa gcgccttaca ggcggtcagg gcaagcccta acaaccccaa ggcaataaaa
     2461 aacttaggct tatttttgct tttttattgt ataattgatt gtcgcctatc cgacagtctt
     2521 gcgactggaa ggaggtgtgt ttcgtgttca ctaactttat ttgctccctt cttgttgggc
     2581 ttttaagcgc tttgttcagt tactggttga ataaccgaaa caagaagtaa aacttaatta
     2641 aggcgactca gcccacaaaa aaagccccag agaatccgac ctctctgggg ctttcgtgtg
     2701 tttcgtgttc acttatttgc aatcaaatta taacagaaat aaatatttat ttcaaaaata
     2761 tcctacaaaa gtctaaaatc cgtaattatt tcttatatgc aacatttaca aataaagtcg
     2821 ctctgagagc tcgtattttt cgatttaaga cgttttattt agtttttggt gtatttcatt
     2881 ggtccaagct aaaaaactct tagaagcgat tttagagcca tttaaaccca cttaattata
     2941 ttctccatga aattcgctcc atgcgtcaaa agctgcgtct gaaattccgc cgtcttcgtt
     3001 cactagttgc attaattttt ccaacgatcg ttttctttcg ggtgtcatat ttttatattc
     3061 caacaatttt tcgtctgtta aatcgaactt gattgcttga attgcttgct ctaatttttc
     3121 taagttttga aaatattcgt aaggaaattt ttccattttt tctttctcca gtctcacaat
     3181 ttttctagaa ataaaatcac ttctttgccg tctatactct c
//
LOCUS       DACBYO010000174         3217 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.177, whole genome shotgun sequence.
ACCESSION   DACBYO010000174 DACBYO010000000
VERSION     DACBYO010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.177"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(31..732)
                     /locus_tag="IVD26_002908"
     CDS             complement(31..732)
                     /locus_tag="IVD26_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP6080807.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(748..1188)
                     /locus_tag="IVD26_002909"
     CDS             complement(748..1188)
                     /locus_tag="IVD26_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAP6080808.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(1188..1763)
                     /locus_tag="IVD26_002910"
     CDS             complement(1188..1763)
                     /locus_tag="IVD26_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAP6080809.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(2611..3090)
                     /locus_tag="IVD26_002911"
                     /pseudo
     CDS             complement(2611..3090)
                     /locus_tag="IVD26_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
BASE COUNT          919 a          683 c          509 g         1106 t
ORIGIN      
        1 ttttctttcc cgtcgtttgg ttttttattt ttagcctaat tcttgacctt ttgcatgctg
       61 gttatccgta aaatattttc cagcaggctt tccttccaat tcagctaatt tttcttggat
      121 ctgacggatc accttttttg catcttctgg attttctaca aaatcgaatt tatccccatc
      181 cacttgtatt ttaggacata catcaaaatc ttcataccat tgattatagc gggtgttcaa
      241 cgtttcataa taggtatata acgtctcatc gctttctagc tgttcatagt cacgcccacg
      301 ttttttgata cgttctagca tcgtgtccaa agaaactttg atatggacca tcaaatcagg
      361 ccgttttttt ggagcaacat catctaactc gtttagcatc gtatctaata agctatcgta
      421 ctgctgtact tcgatatccg ttacccgacc taaatcagcg tttagatgga acaacaggct
      481 atcttcatag atggatcggt ctagcacatt gtcatcgttc actaaagcat ttttcattgc
      541 taaaaatcgc ttgttcaaaa agaagatttg caataaaaaa gcgtactgct caggatttga
      601 ataaaagagc ggcaatactt cgttatcttc gacattttca taaaatggtt tagaatcaat
      661 ctcttttgca agcatatccg tcaaactgct cttacctgca ccaatcgttc ctgaaatcaa
      721 aatcactgac atacaaccct tcctcttcta taagtactcg cctacgtaag tttcaacagg
      781 caatgtttca aaatcatatt cacgtacagc ttggtctgat tttaaatacg tatggagact
      841 ttgtgtaatc atcaagttcg taggtaccgt ctcttcttgt acaatgatca tcggtttttt
      901 caacatagtt gccacaccta attcgtaagc cgttcctgga tcgattgttt gatgctcaaa
      961 gtcaaggata gcaacaacaa attctgcatt tgtcagttct tccatatctt tttcgtatac
     1021 ttcctgcgcc catccagcgc tgaatagttc ataattgctt tcttggtgat gacgtggaga
     1081 gtagaaactt gtgactgttt tgttttcctc caacgctttt tcgatacgac ttactcgatc
     1141 gatttgctcc tctgaaaaaa atggtcctgc taaatatatt tgactcatta ttttgcctcc
     1201 ttcaataata actgattttt aatagatact gctcgtaatt cattgaccag ttccaatgga
     1261 ttgttggaaa agattacttg atccaaccat tttttatcca taaaatcctc ttttgcaaaa
     1321 gtttctaata attgttgcaa gccgctgtaa taaccgccaa tattcaatat tccgattggc
     1381 ttgtcgggcg tcagaccgat tgctatccaa gaaagaagtt gtgagaattc ctccaatgta
     1441 cctagacctc cagggaaaac gaggacagca tctccctttt caaataataa tacctttctt
     1501 tcatcgatcg tttctgtagg aataaatgta gtaacatctt ttccaggcaa ttcagtttca
     1561 aaaagcccat tcggatagat acctgtgact tttccgttat tttccagtac tgttttacta
     1621 atcactccca taatcccgga gtatgaacca ccgtaaacca gttcgatttc ttcttgtgcc
     1681 atgtattttc ctaacgtttg cgcaataaat ttgtaacttt ctttattacc aaaacgggaa
     1741 ccgcaaaaaa cagtaagttt cataaaaaaa cactccctaa ctcaaaagtc tatcttcatt
     1801 ctacacgtgt ttttttaaaa taaaagacta gattttgtag ttttttagtg gtatatagga
     1861 tagacgccac tatatatagt atttagaaaa aaatcatttt tcagccattt tatagataaa
     1921 acaaaaataa ataacgtgtt ttcatcgata tgaaatgact tacttataga agatactggg
     1981 atttcgtcct atatgccaat aacgtgtatt attttaaaca acaaatactt gtttctttta
     2041 ttaacgaaaa aatcattttg ttctcgtgtt atgtttcact gataaatgat gtttctctaa
     2101 ataaaaaagc cgacgaacta aacgatcaaa atttgatcat ttttgttcat cagcttctcc
     2161 taaaaatctt tttgttaacg ataaatagct ggatttgtaa aaatatcact tgaatcgtca
     2221 ctgctggaag aaaattcagt gataaccgca cctgttgcgc ctgcctggaa ctagtgtttg
     2281 atattgggct cgaacgtgta ctgatctcta gcatgaagaa taatttcttt ttttactgta
     2341 taataacttt ctttcctttt tggaatagta caggaaagtt tttttgtttc ctttccttcg
     2401 acataaggta taccagaccc tttcgacaac gaaaggttct catttttcct tcatcgtcat
     2461 ttcaaggagg gtgccgatgc tctggacagt ttcgatcgct cctaaaccaa aatctgtata
     2521 ttcgattctt tctaactctg attctttcat accattcctg tctcaaggta catctattgt
     2581 acttttttct tgtaatccat tctgcctctc ctaactaatt gtcaaatcat cccaagatat
     2641 gtcttcttcc tctttttctt cttggatgat ttctgcattc ggatctactg gttttttcaa
     2701 taataaaatg gttattcctg tgacaaaaga accagctaac aatgcaccaa tgaatgccca
     2761 tggtctggtc atcgtagcga ctgcaaacat tcccgatgcc ggaatacggc tatctgcgcc
     2821 ccaaaacatg cttaatccgc cacctactgt cccaccgact cccgttgcta tgacattgcg
     2881 tgccaagtcg ttcaatacga tagggaaaca tccctctgtg atctgacaga tccccatagg
     2941 aaaagcggtc ttcaatgtat cgatttcttg acgattgagt atatttttac gaatgatttt
     3001 ccctaagaaa taagcgatcg tcaagccgaa tggggttacc atcgaagcta aaatcaatac
     3061 agtgattggt tcatagattc cttctgaaaa tcgtgccaca cccccttatc cagaataaat
     3121 ggtaatccag aaacagccgt gtatctgcgg taataagcct aaccaaacga aaaatatgag
     3181 aagctatttt tgtttggctg ttcttattac ttgatgc
//
LOCUS       DACBYO010000175         3135 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.178, whole genome shotgun sequence.
ACCESSION   DACBYO010000175 DACBYO010000000
VERSION     DACBYO010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.178"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(1014..1304)
                     /locus_tag="IVD26_002912"
     CDS             complement(1014..1304)
                     /locus_tag="IVD26_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080810.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1646..1942
                     /locus_tag="IVD26_002913"
     CDS             1646..1942
                     /locus_tag="IVD26_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080811.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..>3135
                     /locus_tag="IVD26_002914"
     CDS             1949..>3135
                     /locus_tag="IVD26_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAP6080812.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDG"
BASE COUNT         1083 a          527 c          548 g          977 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggttt
//
LOCUS       DACBYO010000176         3048 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.179, whole genome shotgun sequence.
ACCESSION   DACBYO010000176 DACBYO010000000
VERSION     DACBYO010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.179"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(247..468)
                     /locus_tag="IVD26_002915"
     CDS             complement(247..468)
                     /locus_tag="IVD26_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080813.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(566..811)
                     /locus_tag="IVD26_002916"
     CDS             complement(566..811)
                     /locus_tag="IVD26_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080814.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1051..1665
                     /locus_tag="IVD26_002917"
                     /pseudo
     CDS             1051..1665
                     /locus_tag="IVD26_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2035..3036)
                     /locus_tag="IVD26_002918"
     CDS             complement(2035..3036)
                     /locus_tag="IVD26_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HAP6080815.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
BASE COUNT         1004 a          536 c          405 g         1103 t
ORIGIN      
        1 ttttactata tacttcttcc cagaacttgt ccgtctcctt caaattatct ctacctctcg
       61 agttcattgg gtggtttgcc catttattaa acatggaatc acctttctca tactcatata
      121 tttatgtcct atttcaatta tatttatata tgcttaaata aatttgtatc ctgaaattta
      181 ttgtaatatg aagctgtatt ttacatatag taaccaaaga gttaataaaa taaaaagagc
      241 gaaccattat agatcagctc ttttttcatt gctgttttta atcttatcta gaatcacttc
      301 aaatgtttca aaggtattta catctaactg acataaccaa agcaagtact tcttttcttt
      361 gtaagtccaa tcaatattac ggtaagagga cattagatta tggtaccttg ctctttgttc
      421 aactgaagcc aattcccagc gtttttcaaa tattttttct tcttccatta ttgatccctc
      481 gcaagacgct acctcaaact taaataatgg gcagcgaaag tctaattcct tagatctaag
      541 tatagcaaac aaatatgaaa aaaacttaga aggtagtaaa agttcttccg tcttttgctt
      601 tgcttctatt cttaatgtgt ttcgttatcg gtgccctaca aagattttca ttaattacac
      661 actcatttat tgttgtgtat tttctgacat ttctctcttg atcaattatt ttaattccat
      721 gggcatcctg atagttcata ggagaggagc ggctatcaga aatagttgca cctatctctt
      781 gaacttcttt tacaacttct ggaaaatcca tccatcctgc ttcagctgtc aaaagtaata
      841 atctataata tttatctttc cttttcaatc taagaaatcg tcaccccatt ctttttcttc
      901 tattataaac tatttaactt ttagaattca aaaaccgttt gtctatttag agtttaccct
      961 aaatagacaa aaatataaca ttgaaaaatt tagagttcta acgtatgatt agggtgtatt
     1021 ataaacgtta tagaaaagta gggaataaat ttgaaaattg cttatattag agtttcatcc
     1081 atcgatcaaa atgaacaacg tcaaattgaa gaaatgaaaa agtttggcgc tgaaaaaatt
     1141 tttatcgaaa aacaatctgg agcgacgatt agtcatcggc cgattttcca ggaagcttta
     1201 gattttgtca gagagcaaga tatttttatt gtagaagcca ttgatcgact tggacgcaat
     1261 tatgacgaga ttatcgattc agtgaattat ctaaagaaga agaatgtgcg acttattatc
     1321 accagtttac cgatcatggc tgaagcaatt ggaaatcctc tcctagataa attcatcaaa
     1381 gacttaatca tttaaatctc agccatgatt gctgaacaag aacgtactga atcgaaacga
     1441 cgccaggcac aaggaattaa aatcgctaaa gcaaacggcg tctataaagg tcgtcctaag
     1501 ttatacagtg cagacaccaa agatcctcaa cgtcgccttg tctataggag tatcgttcag
     1561 gatcttgaga atggggttgc tatctcaaag attgcaacag actacaatgt gactaggcaa
     1621 acaatttacc gaataaaaaa agaaatcgac caactaattg tatgatttct tttttgaatc
     1681 acgtaattat taattagctt tgtcatcaat acagacaatc attttagatt catctagcta
     1741 agttgattac atttatgtta aaaagaattt agttaacata aatataattg atgcataaat
     1801 cgtccttatt taaaggcatt taacattgac aacttagtat aatgtatctt atgtaaacta
     1861 ataagatttg aattttattt tatacacact cgataataga tcaattttat ggtcccccgc
     1921 atttacgatt gcacaagaga aacataaagt cgacctatta gcatttcttt tcaattcaaa
     1981 cattaaaaaa gtttatacct ctgctactaa aaaatgaaat tatctattta aaatttaaaa
     2041 cggtaaatct gattcatcca aattggaaaa tggatcagcc tgtattggag ctttgtattt
     2101 ctccataata acagatatct ttttttcatt ttttaaaaaa taccttttaa atttcttata
     2161 gtcctctgaa atcaaaatat agcgtgatgg atactcatca aaagaagaat cgtattcttc
     2221 ctttaaaatt cccgatttac ttaatttttc tagtacatca aatactctat cactcaagta
     2281 actccttaaa ttgttatcac tttcccattg aactactttt ctataagttg aattatcagt
     2341 tgaaaagata gaattttcat ccataaacgc atatattagc agcaatcttt catcattgtc
     2401 aaattctatt ggatcaaaaa tatctaagtt gtcatcaaaa tctttatcag ttccggtaac
     2461 ttttttgtta attactgaag gtgtcttgta agaaatagaa tctaaatcaa agcgttttga
     2521 ttctaaatta ttttgtgctt tctcaattaa ataattcact ttttttgtga gaaaccttct
     2581 gatattgtct ttgctatatg ttccataaaa acccttatct tctaaagagt ccctgtactt
     2641 cttaacttct atatactctt cagccaaaac ttgtggaact ggttcatcta agaaaaaaac
     2701 ccctacctcg cctttgctat ttttataaaa gtaatcaatt tctgctatag ttcccgatct
     2761 ataattatca actggagaac ccaacttatg gccaaaaatc gctaataata tatcactatt
     2821 ttctacaatt tgtttattaa taacactttg cccagagcta ttatttatat aagtaggaat
     2881 cgcattcgtt tcccatcgaa ttggcatcaa aattactttt gtattatctg tattttctat
     2941 attccatcta tatatggttt cttctacttc attcctcttt gctgctatat cacctggtga
     3001 tgctataaat acttttatta gatttatggt tttcatttat tgtacctt
//
LOCUS       DACBYO010000177         3004 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.180, whole genome shotgun sequence.
ACCESSION   DACBYO010000177 DACBYO010000000
VERSION     DACBYO010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.180"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..1285
                     /locus_tag="IVD26_002919"
     CDS             <1..1285
                     /locus_tag="IVD26_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAP6080816.1"
                     /translation="TISTATLLFPILTLNIVDAVMRFLMDKDKNKKNIASIAIKVIFL
                     SVIVFGSVMYLLNITKLWQDVYGLEKYIFLYYISYVWNQFLIQFAKGLEKVKAMGIAG
                     IISTIVTIIANIFFLLILKWGLIGFFIANILSQIISATYLSVLVRIWEYIDFEAKDPQ
                     LKREMLNYSIPLIATVVGWWINSTADRYVVSFIVGVSANGLLSVAYKIPQIINTLQGI
                     FIQAWQISAIKEYGDNETAKFYGNTFVMINLLMCITCSSLIILTRPFSHILYAKDFYE
                     AWKYVPFLLIANVLNCASGLLGPILSAKKDSKSMMWSAIIGALVNVIMSVVLVYKIGV
                     QGATIATVICSYVIYVVRKRAVGKDIFIKHYHIVVESWGLLFVQAIIEIYFKNYVIEI
                     IIMIILIIINISYIKQLCYRGRNIISMIKSREHKR"
     gene            1378..2037
                     /locus_tag="IVD26_002920"
     CDS             1378..2037
                     /locus_tag="IVD26_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAP6080817.1"
                     /translation="MKIVAIVPMKLNNKRLPQKNTKAFTNGKPLCYYILSTLLKVKQI
                     DKVYVYCSNPDIKEFIPEGVTFLKRSSSLDQDTTSITQVLAGFTKEVEADVYVMTHTT
                     APFISEKSIEKGLDAVLTGEYDSAFAAKKLQDFLWKDGEPFNYELDNIPRTQDLPPLY
                     EETSGFYIYNRNVMTELHRRIGKKPCIVEVGEIESVDIDEAEDFMIADAIYNHLILQG
                     S"
     gene            2056..>3004
                     /locus_tag="IVD26_002921"
     CDS             2056..>3004
                     /locus_tag="IVD26_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-3-methylglutaryl-CoA lyase"
                     /protein_id="HAP6080818.1"
                     /translation="MNNVQILDCTLRDGGYCNNWEFGFDNTKKIISGLIESGIEIIEC
                     GFLTNKTVYNKNVTKYTTLEELAQIIPEKREGKLFVAMMNYGEYNIEDLPDYDGSSID
                     GIRIAFHKKNCNEALKLCREIKKKGYLVFVQAMVSLNYTDEEFLAVIKNVNQFKPYAF
                     YIVDSFGMMKGKDLTRLFYMIEHNLEKDIQIGFHSHNNMQLAYSNAQKLITVQTNRSL
                     IIDSSVYGMGRGAGNLNTELFVEYLNDNAGKKYQLKPLLYIIDEILNSFYQKSYWGYS
                     LPNYISAVHNAHPNYASYLSYKNTLTIEAMNEIFEMMDEE"
BASE COUNT         1098 a          355 c          554 g          997 t
ORIGIN      
        1 gacaatttca acagccacat tattgtttcc aattttaacc ttaaacattg tagatgctgt
       61 gatgcgcttt ttaatggata aagataaaaa taaaaaaaat atagcatcta tagcgattaa
      121 agttatattt ttaagcgtga tagtctttgg atccgtaatg tatttgttaa atattacaaa
      181 attatggcaa gatgtttatg gattagaaaa atatattttt ttgtattata tatcctatgt
      241 atggaatcaa tttctaatac aatttgctaa agggttagaa aaagttaaag ctatgggcat
      301 agcaggtatt atcagcacaa ttgtaacaat aattgccaat attttcttct tgcttattct
      361 gaaatgggga ttaattggtt ttttcattgc aaatatttta tcacagatta tttcagctac
      421 ttatctgtca gtattagtga gaatatggga atatatcgat tttgaggcta aagatcctca
      481 gctaaagaga gaaatgctaa attactcgat tccattaatt gcaactgttg ttggatggtg
      541 gattaatagt acagctgata ggtatgtggt ttcctttata gtaggtgtct cggcgaatgg
      601 cttattgtct gtggcatata aaatacctca aataattaat actttgcagg gaatatttat
      661 acaggcctgg caaatttctg caattaaaga atatggagat aatgagactg caaaatttta
      721 tggaaataca tttgttatga ttaatttgtt aatgtgcata acctgttcaa gtcttatcat
      781 attaactaga ccgttttcac atattcttta tgcgaaagac ttttatgaag cgtggaaata
      841 tgttccattt ttattaatag ctaatgtttt aaattgtgca tcaggtctgt taggacctat
      901 cttatcagca aaaaaagatt ctaaatccat gatgtggtct gcaatcatag gggcattagt
      961 taatgtgatt atgagtgtag tccttgttta taagataggg gttcaaggtg ccacaatagc
     1021 cactgttata tgttcatatg taatatatgt tgttcgtaaa cgagctgtgg gaaaagatat
     1081 ttttataaag cattatcata ttgttgtgga atcttgggga ttattgtttg ttcaggcaat
     1141 catagaaata tattttaaaa attatgtaat agaaattata attatgatta ttttaattat
     1201 tataaatatc agttatatta agcagttgtg ttatagagga agaaacatta tttcaatgat
     1261 taagagtcga gagcacaaac ggtagacgat gttattttta taaaaagata taatttatta
     1321 atggtcgata attatgaaag gaaaaatatt cttaaaaaaa agagtatagg atgtcgtatg
     1381 aaaatagtcg ctatagtacc aatgaagtta aataacaaaa gattgccaca aaaaaacacg
     1441 aaagctttta ccaatggaaa accattgtgt tattatatac tttcaacact tttaaaagta
     1501 aaacagattg ataaagtgta tgtctattgt agtaacccag atattaaaga atttatacca
     1561 gaaggtgtaa catttttaaa gagatctagt tccttagatc aggatacaac gagtattaca
     1621 caggtattag ccggtttcac aaaagaagta gaggctgatg tatatgtaat gacacacaca
     1681 acagcaccat ttattagcga aaaatctatt gaaaaaggac tagatgccgt gctgacagga
     1741 gaatatgatt ctgcatttgc tgcaaaaaaa ttgcaagatt tcttatggaa agacggtgaa
     1801 ccatttaatt atgaattgga caatattcct agaacacagg atttgccgcc tttatacgaa
     1861 gaaactagtg gattttatat ttataatcgc aatgtgatga ccgagttgca tagaagaatt
     1921 gggaaaaaac cttgcatagt tgaagtaggt gagattgagt cagttgatat tgatgaagcc
     1981 gaggatttta tgattgctga tgcgatttat aatcatctta ttttacaagg tagttaagac
     2041 agggggaagg ttaggatgaa caatgtacag attttagatt gcacacttag agatgggggc
     2101 tattgtaaca attgggaatt tggatttgat aatacaaaaa aaattatttc tggacttata
     2161 gaatcaggaa ttgagattat agaatgtggg tttctcacaa ataaaacagt atacaataaa
     2221 aatgttacaa aatatacgac cttagaagaa ttagcacaga taattcctga aaaaagagaa
     2281 ggaaaattat ttgtagcaat gatgaactat ggcgaatata atatagagga tcttccagat
     2341 tatgatggtt catctattga tggaattagg attgcgtttc ataaaaaaaa ttgcaatgaa
     2401 gcgttgaaat tatgtcgtga gataaagaaa aaaggctact tagtttttgt tcaagctatg
     2461 gtatctctca attatacaga tgaagagttt ttagcagtaa taaaaaatgt gaatcagttt
     2521 aaaccatacg ctttttatat tgttgatagt tttggaatga tgaaaggaaa agatttaact
     2581 cgtctttttt acatgattga gcataatcta gaaaaagata tacagatagg ttttcactca
     2641 cataataaca tgcagcttgc atattctaat gcacaaaaac ttataaccgt acaaacaaat
     2701 cgaagcctga ttattgattc ttcggtgtac ggaatgggaa gaggagcagg taatcttaac
     2761 acagaactat ttgtagaata tttgaatgat aatgcaggaa aaaaatatca attaaaacca
     2821 ttattatata taattgatga aatactaaat agtttctatc agaagagtta ttggggatat
     2881 tcattaccaa actatatttc agcagttcat aatgctcatc ctaattatgc aagctatctg
     2941 tcatataaga atactttaac aattgaagca atgaatgaaa tattcgaaat gatggatgaa
     3001 gaaa
//
LOCUS       DACBYO010000178         2973 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.181, whole genome shotgun sequence.
ACCESSION   DACBYO010000178 DACBYO010000000
VERSION     DACBYO010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2973
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.181"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(237..599)
                     /locus_tag="IVD26_002922"
     CDS             complement(237..599)
                     /locus_tag="IVD26_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080819.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(673..1053)
                     /locus_tag="IVD26_002923"
     CDS             complement(673..1053)
                     /locus_tag="IVD26_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAP6080820.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1135..2310
                     /locus_tag="IVD26_002924"
     CDS             1135..2310
                     /locus_tag="IVD26_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP6080821.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2387..2971)
                     /locus_tag="IVD26_002925"
     CDS             complement(2387..2971)
                     /locus_tag="IVD26_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP6080822.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          924 a          571 c          493 g          985 t
ORIGIN      
        1 ctgttaaatt tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga
       61 aatgattttt cgatcaatta ttattattcg ttatacaacc gttttcaaca tattttgaaa
      121 ataaaatgca ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac
      181 aataaaaaaa gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag
      241 aagaaaggca ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct
      301 tcccaaatat atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca
      361 aacaacggaa cattttcctc tttaatatgt gtatttgtca attccatcaa actaatcttg
      421 ctaacatcga tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt
      481 ccttcagaaa gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat
      541 tttttagtac catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa
      601 atttccacct cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa
      661 aaaatacact ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat
      721 ccaaataggt aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa
      781 ataccttttt ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa
      841 actgattttt ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac
      901 ttttaacaat gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag
      961 tccttgcgtc tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt
     1021 tccttcaatt atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat
     1081 tatactgtaa atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc
     1141 gaatttgata aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct
     1201 gagacatatc aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct
     1261 cccggtgggg tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc
     1321 actctgtctg ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg
     1381 gagttgacga aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca
     1441 gtacaaactt ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca
     1501 ttttcctcta ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa
     1561 aataatcatt tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta
     1621 aaagcaatga ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa
     1681 ttgaaacagt taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc
     1741 catcaagatt taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat
     1801 ttagatgatc tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc
     1861 aaaaattcaa tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta
     1921 gtgatgaacc aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat
     1981 gagacgggtg gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca
     2041 gttaatcagt tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact
     2101 tacttaatgt ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact
     2161 cttgttcgga aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat
     2221 gggcatatgc gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga
     2281 atcaagtatg ctttagagac aatcgattaa atcatttatt caaaataaaa ggacgagacc
     2341 ttactaggtt tcgtcctttt tcataattac tccgtaccat accaaactat tctgaaattt
     2401 caattgtttc aatcactaca tcatgtacag gtcggtcttg tggaccacgt tgtacatttg
     2461 cgatttcatc tactgtgtcc atcccttcta gtacatgtcc aaagactgta tgtcggaaat
     2521 ctagccaagg agttccgcca cctttatacg cttcaatgat ttctgatggg aatccagcac
     2581 cttctagttg tccaagcata ttagctggca catttgtgtt atttacaata aagaattggc
     2641 ttccgtttgt gtttggacct gaatttgcca tagataaagc tccgcgaagg ttgaacagtt
     2701 cacgactgaa ttcatcttca aaactttcgc cataaatact ttcgccaccc attcctgttc
     2761 cagttggatc gccgccttgg atcatgaaat caggaataac gcggtgaaaa atcacgccat
     2821 cataataacc ttttttggaa agttcaatga aattttgaac cgtcttcggt gctagttcag
     2881 ggaataattg aacagtaatg tcaccacggt ttgttttgat aacagctttt ggtccttttt
     2941 cactttttaa atctagttgt gggaatgcca tat
//
LOCUS       DACBYO010000179         2967 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.182, whole genome shotgun sequence.
ACCESSION   DACBYO010000179 DACBYO010000000
VERSION     DACBYO010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.182"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            86..1507
                     /gene="gndA"
                     /locus_tag="IVD26_002926"
     CDS             86..1507
                     /gene="gndA"
                     /locus_tag="IVD26_002926"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAP6080823.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            1700..2386
                     /locus_tag="IVD26_002927"
     CDS             1700..2386
                     /locus_tag="IVD26_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6080824.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            2383..>2967
                     /locus_tag="IVD26_002928"
     CDS             2383..>2967
                     /locus_tag="IVD26_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6080825.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLL"
BASE COUNT          994 a          527 c          650 g          796 t
ORIGIN      
        1 atgttgttct ttagtttgca atgtagccgt gttaagctat aatgtaagag attagggaga
       61 aatcccgtat gtaggaggag ttcatatgtc aaaacaacaa atcggcgttg tcggtatggc
      121 cgttatgggt aaaaatctag ccttgaacat agaaagccgc ggctattcag tggctttatt
      181 caatcgtaca ggggctaaaa caaccgctgt agtagaagaa cacccagata aaaatttcaa
      241 agcaacatat acaatcgaag aatttgtaga atctatcgag aaaccacgtc ggatcttgct
      301 aatggtcaaa gcaggaccgg caacagatgc aacaatccaa gagttacttc ctcaccttga
      361 taaaggcgat attttgattg acggaggaaa tacattcttt aaagatacga tgcgtcgtaa
      421 tgaagagtta gccaactctg gcatcaactt tatcggtaca ggcgtttccg gtggtgaaga
      481 aggagcttta aaaggacctt caatcatgcc tggtggacaa aaagaagcct atgcgctagt
      541 tgcaccaatc ttagagcaaa tttctgcaaa agcagaagac ggagcaccat gtgtcacata
      601 tattggccca aatggagccg gacattatgt gaaaatggta cacaacggta ttgagtatgg
      661 agatatgcaa ctgattgctg aatcttatga cttaatgaag aatattttaa acctttcagt
      721 agaagaaatg gctgatatct ttaaagaatg gaatcaaggc gaattagaca gctatttgat
      781 agaaatcact gctgacattc tgacacgtaa agacgatgaa ggaacaggta aaccagtagt
      841 agatgtgatc cttgatgcag ctgggaataa aggaacaggt aaatggacaa gccaaagcgc
      901 gcttgactta ggtgtgccac ttccattgat cactgaatct gtatttgccc gctatatttc
      961 tgcttataaa gaagaacgcg tacaagcaag caagattttg tctcgtacga acgattttga
     1021 gttcacggga gacaaaaaag aattggtcga aaaaatccga gaagcgttgt atttcagtaa
     1081 aatcatgagt tatgcccaag gatttgctca attacgtgtc gcttcaaaag aatttgattg
     1141 ggacttgcca tttggtgaaa tcgcaaaaat ctggcgcgct ggatgtatca tccgagctcg
     1201 attcttgcaa aaaattacgg atgcctatga caaaaatcct gagatcgaaa atttattgct
     1261 agatgattac ttcgttgaaa tcacgaaaaa atatcagcaa tcagtcagag acgtcgttgc
     1321 cttggctgtc caagctggcg tacctgtacc gactttctca tcagccatcg cttacttcga
     1381 ttcatacaga gcagaacgtc tgcctgcaaa tataatccaa gcccaacgcg attactttgg
     1441 cgcacatacc tatgagcgtg tcgacaaaga aggaatcttc cattactcat ggtaccatga
     1501 agaataatag tctttcggct gttaggaaat gagaaaataa aaagaggacg aaagagctga
     1561 agtcgattgt tatgagtaga cttcagctct tttttaaaat tgctatccat gataaaatga
     1621 ctatagattt ttaagcatat tatcggtata atgatagagt ttttaaaaag ccagtagaat
     1681 agaaaggata aaataataaa tgagcaatat tctaatcatt gaagatgaaa agaacttggc
     1741 acgatttgtc gagctagagt tgaagcatga agggtataac gcagaagtcc actacaacgg
     1801 ccgaactggt ttagatgcgg cattaaataa tgagtgggat gccatattgt tggatctgat
     1861 gctcccagaa ttgaacggtt tagaagtctg cagacgtgta cgccaagtca aaaatacacc
     1921 aatcattatg atgactgcaa gagattctgt gatcgatcgt gtatctggac ttgaccacgg
     1981 agcagatgac tacatcgtca aaccatttgc tatcgaagaa ttattagcac gtcttcgtgc
     2041 attgttgcgt cgaatcgata ttgaaggcga taaaaatgtg gctaaacaaa ctactattac
     2101 ttatcgcgat ttgactatcg aaaaagaaaa ccgtgtcgta cgtcgcggaa atgaagtaat
     2161 tgaactaaca aaaagagaat acgagttgct gcttacttta atggaaaacg tgaacgtggt
     2221 attagcacgt gacgttttac taaataaagt gtggggatac gaaacagaag ttgaaacaaa
     2281 cgtagtggac gtatatattc gttatcttcg caacaaaatt gacgttcccg gggaggaaag
     2341 ctatatccaa actgtacgcg gaacaggtta tgtgatgcgc tcgtgataaa gccgaaaaaa
     2401 tcggaaaaaa gagaactgaa agggccctcc ttgacaatca agtgggcctt tgcgagttct
     2461 ttcttcatat tcgttgtgtt tacaattttc gctgtcatta cctataaatc atctatcaat
     2521 ctgattgtgg caaaagaaag aaacaatgta gagcgtacga tttcagaagt agcttctcgt
     2581 ttggctaact cggatgaaga actgacatta gtaaatacgt atcgtaatct gacgaaagcg
     2641 acaaatgacg gagatgaggt cgtagatcat acttcactgg tcgaaggaaa cttaatgaag
     2701 atcgattcct ttatagctga gctagggcag ccatcaatgg atctttatgt ttatgatttg
     2761 gacgagaact tgatttttaa aacccatgaa aacagtcgaa acctgattca gactacacgt
     2821 aaagttccaa cgatcgttac actagaagga aaaactggct ttttatctat ccagcctata
     2881 tattctaaag gtacaagaga aaagatcggc tatgcgcaaa gcttctatga attatcttct
     2941 ttctatgata ttcgaaataa gctatta
//
LOCUS       DACBYO010000180         2913 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.183, whole genome shotgun sequence.
ACCESSION   DACBYO010000180 DACBYO010000000
VERSION     DACBYO010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2913
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.183"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(1..334)
                     /locus_tag="IVD26_002929"
                     /pseudo
     CDS             complement(1..334)
                     /locus_tag="IVD26_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1011..1084)
                     /locus_tag="IVD26_002930"
     tRNA            complement(1011..1084)
                     /locus_tag="IVD26_002930"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1048..1050),aa:Ile,seq:cat)
     gene            complement(1274..2293)
                     /locus_tag="IVD26_002931"
     CDS             complement(1274..2293)
                     /locus_tag="IVD26_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP6080826.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(2304..2501)
                     /locus_tag="IVD26_002932"
     CDS             complement(2304..2501)
                     /locus_tag="IVD26_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP6080827.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            complement(2524..2817)
                     /locus_tag="IVD26_002933"
     CDS             complement(2524..2817)
                     /locus_tag="IVD26_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080828.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
BASE COUNT          832 a          556 c          501 g         1024 t
ORIGIN      
        1 ttgcacatcg ctgatatgga atatttatgc ttgttggcat caattacttg tcttttcgtc
       61 cgaatatcag cgccgcttgc tttaaaatat cattctccat ttcgagttgc ttatttttct
      121 ttcttagtgc gatcaattct gcttgttctg gtgttaagtt gtctctttct ttgaatgagc
      181 ccgttgattg tgcttgcttc atccatttat cgaaagaaga aggcgtaagc tcatactctc
      241 gaataatttc tgcgcgaggc ttaccagcga gatagagatc gacgatttgt tgtttgaatt
      301 cttttgaata ggttcttcgt tgacgtcttg acatgaaaaa tcctccagtg tgttttttat
      361 tattctacac accttatttt ttctgtctag tctagtgtag ccgattcatg actgacgtgc
      421 cggacgcacg tagcgatcat cggcgttatg actatataaa gtatactttc gttgatccag
      481 aaaggtataa agattaaagt aggctaccta aaaaggtagc ccggaacgaa ttttatcacc
      541 atacttgtga aaggagatat tttttaagtt agtattaaga ttgtgtaata tgatgatatc
      601 tatattttat agtatcagtg ctataaaatc aaaaataagt cactaattaa ctaccactcc
      661 aattgtaagc cttttttctc actttttttc aaaaatatgg tatgcttttt aatggcttca
      721 aatataaaag agtttaaagc gtaacacact tatggggaag tggtttgggg tgcgctttaa
      781 actcttcttt attattatct cacaatttaa cccaaatgtc tttctattta aaaatcaaag
      841 taaaactttt caaatataca gaagtataac tatgtgaaac atcctttcat taatccataa
      901 aaggatacat aaaaaagcca ctcatttgag tggcaatgaa gaaaagcttt agcttgtata
      961 atactcttca aaaaaattct aacacagaac gattcaaatg gctacgttaa tgtaccctgt
     1021 aggactcgaa cctacgaccg gacggttatg agccgtctgc tctgaccaac tgagctaagg
     1081 gtactggttg ttgccacata aagccataaa caatcaacca gtagaatgtg tggcaacaaa
     1141 cctgttatcg catagcttgg agtgtgacta tttatgggtg atagtgaaga tatgcgataa
     1201 catcactatt ttatcgaata atttttatag ttgtcaatat agttatgtac tgctcctcaa
     1261 cgaggagcta tttttatcgt ttaggaatat ttaaatacca acgtttgtca tggaaatctt
     1321 gcgcaccgcc tttagtgttt ccctctggat cattcgttgc ccgcatcatt acatagactt
     1381 tcttactagg aaaattacgc atattgaaag atacatgata accaacattt ccagaagtat
     1441 tataagcttg gtttacatct ggtctataaa ttccatcagc tcttactcga gctaattctt
     1501 tcccagtatt gtagtccata atgaaaatat actcgtattt atagttagca atgtgccatc
     1561 cagccacatg caagtttgcg ttttcgattt ccccaaactg atcaatgtgg gcgtgatttg
     1621 ttccatctgt cagcgtagga ttagctgcac cagctcgtgt tggatcaatg acaggcttgt
     1681 tttcagaagt tgttggattt tcatcggtaa atccatgagc taaatcatat gctaattttt
     1741 ctttacttac gcccatttca gaaagataac cgtaaggatc tgtatgatcg ccccagatgt
     1801 tttgtgttac ccataaatgc gatttgattc ccggttggtt ataaggagtg tccaacgtta
     1861 atggaatacc atatttcatt gctgaatctc tagccaattc aacgtatgcc ttgtagtttt
     1921 tctcaaacgt tgctttatca tgtgtgtgtt gtaactcaat ctgcacagga ctgttggcat
     1981 tagcatacga accagcaccg tactgtacat aaccaggttg accgacttga taaacaattc
     2041 cgccgtctcc cacaatataa gcagtataag cgctagtcca tgaacgttgc atatactgcg
     2101 cttcattgcg tcctgttgct gtttcattag ccgtttcatg cagtaaaatg tactgattat
     2161 ttgctacttg tgagctacct tcgtttgggc ctaaattaaa ttcattgtta atcgtatagg
     2221 caaacccatt aattggcaat aaaaaaagag ccgttaatag gctcatcgca gtaatagtaa
     2281 ttttcttttt catttgtttc ctcctatttt ttcaaattat aagccgacac gccagtgata
     2341 acgcctaaaa atgttgctac tgcattgata gtgagtactg tcatatctgt tccattccat
     2401 ccatacgctt tgcctagtgt tgcaactaat acagatgcag ctggcaatac tgttaaaact
     2461 gtccatttaa tgacttgata atacttatcg ggtaaaatca tttcttctta actcctttct
     2521 tttttaccga gatctttctc taaataaagt tttgatttgt tgtgtgtgtt ctaccaattt
     2581 ttctgtatgt gtatctaatc tttcatcgtg tttctttagt tcttcatgaa tcatcaatcg
     2641 atctgatttg ctcgattcta aatctttagt cagcaaatct aaattgtgac ttacttttga
     2701 aagagtttca gtaatcttcg agaaagatgc agtgactggt cttattacta ataaaatcaa
     2761 agaaacaatc gcagtgattg atcctgcgat tgttccccat tctcctaaat taatcatgtg
     2821 acaactcctt taccttaaat aaaaacgcat caattaagat gcgctcttat ctttattaat
     2881 gattttatct gcttcttcgt ctgtaatgca taa
//
LOCUS       DACBYO010000181         2800 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.184, whole genome shotgun sequence.
ACCESSION   DACBYO010000181 DACBYO010000000
VERSION     DACBYO010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2800
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.184"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            137..748
                     /locus_tag="IVD26_002934"
     CDS             137..748
                     /locus_tag="IVD26_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP6080829.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="IVD26_002935"
     CDS             821..1750
                     /locus_tag="IVD26_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAP6080830.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1908..2645
                     /locus_tag="IVD26_002936"
     CDS             1908..2645
                     /locus_tag="IVD26_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HAP6080831.1"
                     /translation="MLISCGARLAPFDIRELRELMSEDELELDKIGDRKTALFVIISD
                     TDDTFNFVVSIMYSQLFNLLCDKADDVYGGRLPVHVRCLLDEFANIGLIPKFEKLIAT
                     IRSREISASIILQAQSQLKAIYKDHADTIVGNCDSTLFLGGKEKTTVKELSETLGKET
                     IDLYNTSETRSNQKSFGLNYQKTGKELMSQDEITVMDGGKCIYQLRGARPFLSDKFDI
                     TKHKNYKLLEDYDKKNLFDVEEYLKQR"
BASE COUNT          975 a          390 c          521 g          914 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aatattttgt gtaaataact cgtccttctg caaaataatg ggttactcag
     2701 taaacattga agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga
     2761 atttttgatt gtatgtatca aagatggata ctaggaaacg
//
LOCUS       DACBYO010000182         2798 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.185, whole genome shotgun sequence.
ACCESSION   DACBYO010000182 DACBYO010000000
VERSION     DACBYO010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.185"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            433..600
                     /locus_tag="IVD26_002937"
     CDS             433..600
                     /locus_tag="IVD26_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6080832.1"
                     /translation="MVYLNKKQTCEFLGIDNNTLDKWIRIYNFPVIKIDGIIRFDVED
                     IKGFMDTFKKI"
     gene            674..1900
                     /locus_tag="IVD26_002938"
     CDS             674..1900
                     /locus_tag="IVD26_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6080833.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFKEITGISSEKFQKTFPTRQLAIKA
                     ENEMKKKIAKVLREENANSLELKGQIKFKEFYKSKWLPRYELGQTTRSHKAPSDITII
                     NTKNLFRLHILPIFGEYAMSYLNANTEIISDELTKKSKEYANIKIIKCYVRSMFDIAE
                     VLNYIEFNRTTKIIQSITAPKKVALEEKRIREGKQALSSKELTDWLDAVRDDFNDQLL
                     SFHDYTLFMLTLYLGDRKSETYALQWKYIDFENQTVRLKYALDKHTKKKFTKGRKDTI
                     IQVPEIVMTLLQEWKSVQAEQLLKLKIKQTPDQYLFSYSKPSGEVNCPVHTDYLNYRI
                     NSIKKRHPHLVHLTPHKLRHTYATLARQGGADMNQISNALTHSGISTTKIYVNTPDLV
                     DKAVFEAFQRGLQKSN"
     gene            complement(2058..2675)
                     /locus_tag="IVD26_002939"
     CDS             complement(2058..2675)
                     /locus_tag="IVD26_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6080834.1"
                     /translation="MAKIGYARVSSLDQNLDRQLELLSECDKIFSDKASGKDTNREGF
                     QEMMKFIREGDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEEERRYIRETQQQGIALAKAKGKYKGGTLKYRENDPRLQLAF
                     NLFLTGSTDKEVEELTGINRRTFRRYRMKHGITNEVREQKNKSFS"
BASE COUNT          965 a          465 c          424 g          944 t
ORIGIN      
        1 attttaaatt tttacatacc tgtttatgaa aaactaaata atctgtcaaa aaaatatgat
       61 tgttcatttc taaatatgtt ttccaatttt aaaatctttt ttagcatttt tgtttccttt
      121 tcatatggtt tttcgttgtt aatagtgact aggatgatat tcctattttg accattgaca
      181 attaaatata atttttgaat aacgttccct gctattcgag ctaagaattc aagtacgcca
      241 tgacctattt agcgataact acttagagat ttctttttgt tttgggaaga caaaatgcca
      301 tgacaatagc agtagataat gatacttccg taaggctcgc cgtaaactgg ggagaggtga
      361 aattcctatg tgcttaccca agtcaattca aaaattttag ttcatttata aggggatgat
      421 tttattaaat caatagtcta tctaaacaaa aaacaaacct gtgagttttt aggaattgat
      481 aacaatactt tagataaatg gattcgtata tataattttc ccgtaataaa aatagacggt
      541 ataattcgct ttgatgtaga agatatcaaa ggctttatgg atacgttcaa aaagatttga
      601 attttacttt tgactgcata tactaaaagt agcgaaatat actgccttac ttttttatta
      661 aggagtgagg aagttgccta cgaagctttc aaatggaaaa tataaaacta atttgagata
      721 tccaaaaaaa tttaaagaaa ttacaggtat cagttcagaa aaattccaaa aaacatttcc
      781 aactaggcaa ttggctatta aagccgaaaa tgaaatgaaa aagaaaatcg caaaagtctt
      841 aagagaggag aatgcaaatt cattagagct caaaggtcaa ataaaattca aggagtttta
      901 taaatctaaa tggcttccta gatatgagtt agggcaaact actagatccc ataaagctcc
      961 aagcgatata accatcatta atacaaagaa tttatttcga ttgcatattc tgcctatatt
     1021 tggtgagtat gccatgagct atcttaatgc aaataccgaa ataatatcag atgaactcac
     1081 aaaaaagtcg aaggaatatg caaacataaa aatcattaaa tgctatgttc gttccatgtt
     1141 tgatattgca gaggttctaa attatattga atttaatcgt acaacaaaaa taattcaaag
     1201 tattactgca cctaagaaag ttgctctgga agaaaaaaga atacgagaag gaaaacaagc
     1261 tttatcttcg aaagaactca ctgattggtt agacgctgta agagatgatt tcaatgatca
     1321 attactttcc tttcacgatt acactctttt tatgcttact ttatatcttg gggatagaaa
     1381 gagtgagacc tatgctttgc aatggaaata cattgatttt gaaaaccaaa cagtccgtct
     1441 taaatatgcc ttggataaac acacaaaaaa gaaatttaca aaaggtcgaa aagatactat
     1501 tatccaagtt ccggaaattg taatgacact attgcaagaa tggaaatcag tgcaagctga
     1561 acaactattg aagttgaaaa ttaaacagac acctgaccaa tatcttttta gttactccaa
     1621 accttctggt gaagtaaatt gtccagtcca tactgattac ttaaattatc gaattaattc
     1681 tataaaaaaa agacatcccc atttggttca tttaactcct cataaacttc gacatactta
     1741 cgcaacttta gctagacaag gtggggctga tatgaatcaa atttctaacg ctttgacaca
     1801 ttcaggtatt tcaactacaa aaatttatgt gaatacacct gatttagttg ataaagctgt
     1861 gttcgaagcg tttcagcgag gattacaaaa atctaattaa tgtgttctag aatgtgttct
     1921 aaatataaaa aaaagacact ttccaaataa ttggaaagcg tcttgaacgt tgatatataa
     1981 aggatattaa cgttttgaga attgagatgc tttacgagct ttcttaagac ctggtttctt
     2041 gcaaaattat attagcctca actgaaagat ttattttttt gctccctaac ttcattagta
     2101 ataccatgtt tcattcgata tcttctaaac gttctacgat taatccctgt tagctcttca
     2161 acttctttat ctgtagatcc agtcaaaaac aaattaaatg ctaattgaag tcgcggatca
     2221 ttctcacgat attttagcgt acctcccttg tatttccctt ttgctttagc gagtgcaatt
     2281 ccttgttgtt gcgtttcgcg aatataccga cgttcttctt cggcctggta cttgtatagt
     2341 tcgataatta agttattaag taatcgacgt aaattatcat cagtgatacc tgttaacgct
     2401 ggcaaattca aaacttccag tgtagctttc ttcagctgaa ttaaattcat cgtttctgtt
     2461 agctctttat tatttcgtcc aagtcgtttt aattctgtca caacgacaat atcaccttca
     2521 cgtatgaatt tcatcatttc ttgaaatcct tctcgattgg tatctttccc acttgcttta
     2581 tcactaaaaa ttttatcaca ctctgataat aattctaatt gtcggtctaa attttgatct
     2641 aagctgctta ctcgagcata cccaattttc gccataataa aactccttta aaattctgaa
     2701 atccggatca tttttaaatt ctgttgccca actctgttgt catttttcta gataaatggc
     2761 ataaattttc agcgctaagt gacaaaagca actaattt
//
LOCUS       DACBYO010000183         2778 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.186, whole genome shotgun sequence.
ACCESSION   DACBYO010000183 DACBYO010000000
VERSION     DACBYO010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.186"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="IVD26_002940"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="IVD26_002940"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAP6080835.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="IVD26_002941"
     CDS             complement(1297..2133)
                     /locus_tag="IVD26_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6080836.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..>2778)
                     /locus_tag="IVD26_002942"
     CDS             complement(2317..>2778)
                     /locus_tag="IVD26_002942"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="broad specificity; family IV; in Corynebacterium
                     glutamicum this protein can use glutamate,
                     2-aminobutyrate, and aspartate as amino donors and
                     pyruvate as the acceptor; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAP6080837.1"
                     /translation="VLSGDKSHVKGYIEGLNMLSSMRLCSNVLSQQIIQTALGGYQSV
                     DELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYIFPKIDTKRFNILDDEKFVLD
                     FLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTAKKMREFLATYRQK"
BASE COUNT          799 a          580 c          455 g          944 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggac
//
LOCUS       DACBYO010000184         2679 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.189, whole genome shotgun sequence.
ACCESSION   DACBYO010000184 DACBYO010000000
VERSION     DACBYO010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.189"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..466
                     /locus_tag="IVD26_002943"
     CDS             <1..466
                     /locus_tag="IVD26_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080838.1"
                     /translation="IQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKH
                     EVKVGDRWENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNG
                     LVSIKGTGKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
     gene            1486..2655
                     /locus_tag="IVD26_002944"
     CDS             1486..2655
                     /locus_tag="IVD26_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP6080839.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
BASE COUNT          998 a          358 c          421 g          902 t
ORIGIN      
        1 aattcagtcg tataaaggtc gtttagttat gaccaaaaaa gatgttacac gttatacatc
       61 ctcaagaact ggaggcctat atgactatgc accattagat gcattgaaat ataaagatca
      121 tttaaagaaa catgaagtaa aagttggtga tcggtgggag aatgcatctc ataaagcata
      181 taattccaaa atagtctata cagtagaaga tgccgatgag caaaatatca cattacctgt
      241 attcaattat tggggaacag ttgtgaaagt aaatgggaaa aagagcacta tagaaaatga
      301 caatggttta gtgtctatta aaggtacggg gaaaagaact atagttgagg tttcatctac
      361 gtatccaact acgatgattc tatctttatt aattagttca ataactttta tattcttatt
      421 tacacgttat ttaataagat gctgcggtga aatgaaaata gattagatag atattataaa
      481 tatgttgatt ctattttcat agcaatggag aaaatacatt agcaatatat aaaagaaggt
      541 atcaagagtc acagtgaatt tattccgaaa agtgaaaaga gcaaatataa aatttaatga
      601 aaatatagaa ctaaatagga aaacgtagac gtaattttct acgttttcct tttcatatat
      661 attaaatatt acggaaaatt atataaacta atttagtgtt ttgtttgtaa ttcctaattt
      721 tgctccactt ttagataatt tttaggtcta tttaactcat cagacattct atgctcattt
      781 ttctccaaat ttgtttcaac tctttcgtac ttaattttgc gtatttgaaa attcttcttt
      841 tagagtactt ttattacgat actagtatga tatatatcta tagcaaacag ttaaaatctt
      901 cctaaaataa gcgaatagca ttcctaaaac ctataaaatt tttagatgaa gcgacaagtg
      961 gacaattaat aaactacttg aacatgaaat tatggatcac ctttcaaatt tagaaaatgg
     1021 aattcttata cttattgcgc aacatttatt gattgcaaaa ttatgtgaca aaaaaaacta
     1081 gtagaagaaa gaataatggc ttgataataa agtactacct attaaaggta gtactttatt
     1141 taatttagta taaattaaca tactactata ttttaggttt catattatat aaattgataa
     1201 tatactacca tttgttggta gtataattta aaggtaataa gttattcttt tattactatg
     1261 tttgggtttt atagcaaaga aagtttaata agagtttgga cctagcaaac aatattaatg
     1321 aggtcattaa atcttattat ctttagtgat ataacgaaat atctacacag acaaaatgat
     1381 agcgtaaaat attttgtgta aatagatatt tagggtagaa aaaaagaaag tccattctgt
     1441 aaaattaaag ttaccacaac cgaaatttta taggaggact ttctcatgcc caattttact
     1501 acagaaatta tggaaacact aatcaataaa ggtgatttag atgaattatt tcgatgtcat
     1561 ttagaattag ctgttaattc attattgcag gctgaattaa cagcttttct tgattatgaa
     1621 aaatatgatc gtgctgggtt caattcaggt aattcccgta atgggaatta ttcacgttca
     1681 ttcagaacag agtatggaga attaaatttg gtaattccta gagatagaaa tggtaagttt
     1741 tctcaacaaa ctttacctgc ttataaaaga accaatgact ctttagaaac cactattatt
     1801 cagctatttc aaaaaggaat tactatgtct gaaatctctg aattgattga aaaaatgtac
     1861 gggcatcact atacgccaca aaccatttca aatatgacta aaatagtttc tgaagatatt
     1921 attgccttta aagaaaggtc cttagaatcc agatactctg tcatttttat ggatgctact
     1981 cacattcctt taaaaagaca aactgtttca aaagaagcag tttatattgt aattggcatt
     2041 cgattagatg gaaccaaaga ggttcttggg tttagtcttg ctccaactga atctgcttat
     2101 gtttggaaag agattcttca agacctaaaa gaccgtggtt taaaagaggt tttattagtc
     2161 gtaactgatg gtttaagtgg cattaacgat agtattcata gtgtttatcc aaatgctcaa
     2221 tttcaacaat gttgtgtcca tatatctaga aatatcgctc ataaggttcg tgttagtgat
     2281 cgacaagaaa tctgtagcga tttcaaatta gtttatcaag caagttcaaa agaagaagca
     2341 aataatcaaa taaggtttat gatagataaa tggaaaaagc agtatccacg agtggttaaa
     2401 ttgctcatga atcctgctat attaaccttt tataatttcc ctccgtcaat cagaagaact
     2461 atttattcaa ctaatttgat tgaaggtttt aacaaacaat taaagaaata taccaaaaga
     2521 aaagagcaat ttcctaatga agaatctctg gagagatttc tagtatctca attcaacaac
     2581 tataatcaaa agtttctatg ccgagttcat aaaggtttta aagaaataca tgatacatta
     2641 gaatcaatgt tttaacttga tcaacagaat gggcttttc
//
LOCUS       DACBYO010000185         2669 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.190, whole genome shotgun sequence.
ACCESSION   DACBYO010000185 DACBYO010000000
VERSION     DACBYO010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.190"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            12..242
                     /locus_tag="IVD26_002945"
     CDS             12..242
                     /locus_tag="IVD26_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080840.1"
                     /translation="MGFRTKRSLSSKKNWVYSQTIFYGGIVLISLLSSTLYSLNIIDV
                     STSNSISIIGIIIAAIITQLFLVFGEKKRSKK"
     gene            complement(333..698)
                     /locus_tag="IVD26_002946"
     CDS             complement(333..698)
                     /locus_tag="IVD26_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080841.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            906..1388
                     /locus_tag="IVD26_002947"
     CDS             906..1388
                     /locus_tag="IVD26_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080842.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1585..2475
                     /gene="pstS"
                     /locus_tag="IVD26_002948"
     CDS             1585..2475
                     /gene="pstS"
                     /locus_tag="IVD26_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAP6080843.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT          923 a          425 c          518 g          803 t
ORIGIN      
        1 gaaattcaag tataggtttt agaactaaac gaagtttgtc ttctaaaaaa aattgggtat
       61 actcacaaac tattttttat ggaggaattg ttttaattag tttactttct tcaacacttt
      121 attctttgaa tattatagat gtttccacct caaattcaat atctattatt ggaatcatta
      181 ttgctgcaat tattacacaa ctgtttttag tgtttggaga gaagaaaaga agtaaaaaat
      241 agaaaaacta gtgatagttt tggtgatata agaaaaacat atatgtataa aaagaagaaa
      301 gtagcttctc tttgtacata tatggtttgt ttttatggat gccgagcttt tttataagat
      361 aaggctaccg cccataacga cccaaggatt tgtggaacta agtaaatacc tgcaagaagc
      421 aagatcagct gggtcggttt taaaggatga tagaagtaac gccattcagt aaaattggcg
      481 caaaataaat aggaagtgac agtagatata atattggcaa tgaataaaga tataatacgc
      541 ctgttccttt gaaaataata tccagcaaaa agagataaaa atatcaatgt gatgaacccg
      601 cttacggaat gataacgaaa atcaagcagt aaggcgaaat gcacataagg aacaaaagat
      661 aaaagcaacg gaaggttttt ccagcaagtt tttatcatct ttcatcacca cctaacaagt
      721 gttattattt tgttagtttt attgtaaatt gaatcctgca ataatcaatt actttttcat
      781 tatttctaga ttaaatgaat aaactctcat gccattatct ctaaaaaaaa agtttttccc
      841 cctaattttt ttagatagaa aattgtatag tatgatgaga gaaaaagtag tttgggggaa
      901 cgttaatgag aagaaaagca gtaatcgatc ggctttattt atttttttgg ttttttccta
      961 tcgttttgct accttttaca tgggtaaatg ctgttgtaca aggtgcggag atattaggcc
     1021 tgatccaagg aagcggattt gtggtttcta ggaattttcc agctttgatt gttttctatt
     1081 tagtgataag tgtaggtctc ttattaccaa aatctctgat caatcactac aattggcagc
     1141 tgctttactt ttcttgctta ttagtattta catctatgtt ttctttgctg cctcgcttga
     1201 ttatcggccc taatggtttg agcgagagtg gattgaagga tttagcttat tcctccatgt
     1261 atttcttgac gatcaaacca tggttctatt tagtaattgc ctcatttatt cttgcaacat
     1321 ttttttactt ctggacagaa atcaggataa aaagtgaacg atctgtatct ataaaaaata
     1381 actattgatg gtggatcatc agtaaaaaaa catatgagct gcgtaaaatg catgtttctc
     1441 atatgctttt tttattatta tgtaaagaat gcgaaaaacg tttacatgat ttttacataa
     1501 cttaactata tttttacagc aaccatacga gggatttaca gtcgactgat aaactttagt
     1561 tgtaaataag aaaggagcaa taaaatgaaa aaagtattgt ttactctagg tatgatggga
     1621 attcttttag ccggatgcgg ctcaggatca ggaaatacag atggctctgc cacacaaaat
     1681 aattcaagtg actcaaatga acaagtaaaa atcgttgcgg taggttcgac agcattacag
     1741 ccgttagtcg atgcagcaca agaaagcttt gtacaagaaa atccaaatta tcaaatctct
     1801 gtacaaggag gaggaagcgg aactggtttg agccaagtcg aagctggagc agttactatc
     1861 ggaaactctg atgtatttgc agaagaaaga gacggagttg atgcttcaaa attagtggat
     1921 cataaagtag cagtggtcgg gatggcacca atcgtcaata aagatacaga tgtcaaagat
     1981 atcaccaaac aggaattgat tgatatcttt acaggaaaaa tcactaactg gaaggaagtt
     2041 ggcgggaaag atcaaaaaat caacgtcgtg aaccgtgcaa acggcagcgg tacccgcgcg
     2101 acattcgaaa aatggggact ggatggtgct acccctgtgc agtcccaaga acaagattca
     2161 tcaggaacag ttcggcagct ggtaagtcaa acaccaggag caatcagcta tttagctttc
     2221 tcatatctcg atgattccac acaagcacta agtatcgacg gtgtagaacc aaaagaagag
     2281 aatgtagcag ataacagctg gggaatctgg tcatatgaac atatgtacac gaacggaaaa
     2341 ccttcccctg aagtccaaaa attcttagac tacatgatga cagaagaaat ccaagaagga
     2401 cctgtcaaag aattgggcta tttaccaatc acaatgatgg aagtagaacg tgatcacgaa
     2461 ggaaatatca aataactagc agataaacat gccacggtag tcgttactat taaggaaaaa
     2521 tcaactatgt ttccccacat atacattttt cctttaattg tgaaaaatag ttcctcatat
     2581 tttgccgttt tttgagctaa taccgagggt cagctgattg aacaccgttt attcgaaaaa
     2641 aagagctacg acatagaact gtcgtaact
//
LOCUS       DACBYO010000186         2603 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.192, whole genome shotgun sequence.
ACCESSION   DACBYO010000186 DACBYO010000000
VERSION     DACBYO010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.192"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            111..1253
                     /locus_tag="IVD26_002949"
     CDS             111..1253
                     /locus_tag="IVD26_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP6080844.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRYPTTDALEIIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CDGVIRRFDLAINDMCGLLDIPVLSEKYRNGGADCRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRGTKAVQAVEELLLTYNPHG
                     LVFYLITDFVQFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDIADVIESEGVFYE"
     gene            1246..1452
                     /locus_tag="IVD26_002950"
     CDS             1246..1452
                     /locus_tag="IVD26_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAP6080845.1"
                     /translation="MSNAQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEQVIDKLDAI"
     gene            1531..>2603
                     /locus_tag="IVD26_002951"
     CDS             1531..>2603
                     /locus_tag="IVD26_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP6080846.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDRKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVLENDTKKKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQQVMKKRPKAEPFVIDGRGNFLFVNHKGKPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASK"
BASE COUNT          899 a          492 c          580 g          632 t
ORIGIN      
        1 tcccaaagtt gtgagtagta atgagaagtt ttaagaagat agtgcatatc acactttttg
       61 aatagaggtt tacaggtatt tcaaggctat tgtgggattg gaggaataca atgaacaatt
      121 tagaatttgc acttgaaatg aagaacaaac gtcttgcaag cggtctttca caaggagaac
      181 ttgcaagtct tacccatgta tcaagatata gtatcaaccg ctttgagaac ggaaaagcca
      241 acgccagcaa ggaaacacaa aatattatcc tgcgttgtct gaattattat atctgcgata
      301 agccttttta tctgctcgtt gattatctgt ctgtccgtta tccaacgact gacgcattgg
      361 aaattatccg aaaggtgctt ggcatgaaag cagattattt tatccattat gactatgggt
      421 attatggcta taaagagcat tacgcctacg gagaaatcaa ggtcatggct tctgatgacg
      481 aacacatggg cgtattcttg gaattaaaag gggcaggctc acgcaacatg gaatatgtct
      541 tgcaggcaca gaacagagat tggtattcat ttttaaaccg ctgtcttgac tgtgacggtg
      601 ttatccgacg ttttgacttg gcaatcaatg atatgtgtgg tctgttggat attcccgttt
      661 tgtctgaaaa atacagaaat ggcggtgcgg attgtcgctg taaaaattat gaaaatgtgc
      721 agggtggaaa actaagcgga aaaaaccgta atttagcaag caccctttat atcggttcaa
      781 aggcaagcac aaaatacttc tgcctgtatg aaaaacaaaa ggaacaggca accaaaaaga
      841 aacatacgga tattatcaat cgttttgaaa ttcgtctgcg tggtacaaaa gcagtacagg
      901 cagttgagga attgttattg acatataacc ctcatgggct ggtgttttac cttattactg
      961 attttgtgca atttcccgac tatccgctgt gggagatatt catttcccat gacagtttac
     1021 cttttgaaat gaaccccgta cctgtcaata tggaacgcac tctgcaatgg ctggaaagac
     1081 aggtcatgcc gtcaatcgtg atgatagagg aaatcgacag gctgacaggc tcaaactaca
     1141 tgaaaatgat tgatgaatgt acccacctct ctgaaaagca ggaaatgctt gtggaacaga
     1201 tgtgtacgga catagcagac gtaatcgaaa gtgagggggt gttttatgag taatgcacag
     1261 gatattcccg tatgggaaaa atacaccctt accattgaag aagcgtcaaa gtatttccgt
     1321 atcggagaaa acaagttaag acgattggca gaggaaaaca aggacgctgg ctggctcatt
     1381 atgaatggca accgcataca gattaaacgc cgacagtttg aacaggtcat tgataaattg
     1441 gacgctatct aatgcaaatg agccttgtat gtgttatgat gaacacaagt catatcaagg
     1501 ctctttccaa caaggaaagg agcagacacc atgaaagaaa aaagacggga taacaaaggt
     1561 cgtatcctgc atactggaga gagccaacga acagacagaa aatacttata taaatatgta
     1621 gacgcatttg gaaacacaaa atatgtgtat gcttggagat tgacacccac agacccgaca
     1681 ccaaagggaa aacgggaaaa accctcactt cgagaactgg aacagcagat aagacgggat
     1741 attgaggacg gtatcgacag cactggcaag aaaatgacgc tttgccaact ttatgccaaa
     1801 cagaacgcac agagggcaaa tgtgaagaaa agcacacaga aacaacggga acaactcatg
     1861 cggttattga aagaggacaa gttaggtgct aggagcattg atacaatcaa accctctgac
     1921 gctaaggaat gggcgttacg catgaaagac aaaggctttt cctacaatac cattaacaac
     1981 cataaacgct cgttaaaagc gtcattctac atagccattc aagatgatta tgtgaggaaa
     2041 aatccctttg atttcaagtt gagtgaagtc ctagaaaatg ataccaaaaa gaaagtcgca
     2101 ttgacagagg aacaggaaca agccttactc tcattcatca agacggacaa tgtgtatcac
     2161 aagcattatg atgatgtgct gatactgtta aagacaggac ttcgtatttc ggaactgtgc
     2221 ggactgacag tagccgacat tgatttcaag aatgaagttg tgattatcga ccaccagtta
     2281 ctaaagagca aggaacaggg ctattatatt gaaacgccta aaacaaaaag cggaataagg
     2341 caagtaccat taagcaaaga aacgatacag gcatttcaac aggttatgaa aaaacgtcca
     2401 aaggcagaac catttgtgat agacggacgg ggcaacttcc tatttgtcaa tcataagggc
     2461 aagcccaaag ttgcgattga ttataacgcc ttatttatcc gtatggtaaa gaaatacaac
     2521 aagcaccaca aggacaatcc attgccacat atcacaccgc atacgctacg ccatacattc
     2581 tgcacaagac tggcaagcaa gaa
//
LOCUS       DACBYO010000187         2602 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.193, whole genome shotgun sequence.
ACCESSION   DACBYO010000187 DACBYO010000000
VERSION     DACBYO010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.193"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            281..973
                     /locus_tag="IVD26_002952"
     CDS             281..973
                     /locus_tag="IVD26_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP6080847.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1300..1797
                     /gene="dfrG"
                     /locus_tag="IVD26_002953"
     CDS             1300..1797
                     /gene="dfrG"
                     /locus_tag="IVD26_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAP6080848.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1869..>2602)
                     /locus_tag="IVD26_002954"
     CDS             complement(1869..>2602)
                     /locus_tag="IVD26_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAP6080849.1"
                     /translation="YWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHFI
                     CQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEEA
                     ISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTNS
                     FIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSADK
                     KVLTPAQRLGITDKQFDWKDIIYFK"
BASE COUNT          974 a          365 c          461 g          802 t
ORIGIN      
        1 cgttttttgt aataaataca gtaatctatg aaatgaaaag ggttacgttt aataaaactt
       61 gcttttttgt ttttgttcac cataaatatt tatttaagaa agtattaacc tgcatttttc
      121 tctataaaaa agatttttta aatagataaa aaaggaggat taaatgagta tttgatagta
      181 tttatattaa aattacatat gtaatttaaa aacgcttgac attgtgtttg agatcactta
      241 cttttagcat gtaaaagtat tggattaagg agctatgcaa atgaaaaaga aatttattac
      301 tggtgggatt gtcgttgcat ttctatgtct aattggctac acaggcacgc ggtacgcaaa
      361 tgaaattatt ttgtggggtg gagagacaga tattgataca atcaatgaga atctgacaca
      421 gcttgatcat acattgacag ataaagagca agcgattaca gatcttaccg ctcgactagc
      481 acaaaaagaa cagacattgc aagattcaaa ggcagatgtc caagaatacc aaacaaaagt
      541 aaatgaatta gaaaaccaaa aaaatcaatc ggcagcagaa aaacaaaact tagaaagtca
      601 attagtcagc aaggatgcac aactacaaag caaacaaaat gaaatcaatg tcaaactaga
      661 tgagatcaac caaaaaaatg atgaaatcaa tcatctgaat gcagattgga cagcaagact
      721 acaagaagca caagcaaaac tttcagaatt acaaaatact gtaaatggtt tgaatcaaca
      781 aatcgcaaca ctgacacaag aaaaaacaaa tgtagaaact cagttaacag atacacaaaa
      841 gaaattagac gaagcaactg ctgaaaactc aagcttgaaa caatatattc aaaagttaga
      901 aaaagcaaaa gatgaagtgg aagatacagc tgataaatct cagcaaattg ttgaagaaca
      961 tttgcgtaaa taatctttct taacaagtaa acctaaatta gtaaagaagc aacagtaatc
     1021 tatactaagt agttcagttt tggagtacaa aatgacaaaa tgtacttcaa aatggactac
     1081 ttttttcatt ttaacttaca taccaaatta catacaaaat gatttataaa atgcaattga
     1141 aaatgataat tgaatgaaaa tttgtgattt tgtggtatta tgataatata acttatagaa
     1201 aaaattgctt attcaactaa cgggcaggat aatgagaaaa ggttttttga tagaaataag
     1261 aaattagatg gtaaattagt taaaaaggct gtgttataaa tgaaagtttc tttgattgct
     1321 gcgatggata agaatagagt gattggcaaa gagaatgaca ttccttggag gattcccaag
     1381 gactgggaat atgttaaaaa tactacaaag ggacatccga taatattagg taggaagaac
     1441 cttgaatcaa tcggaagagc cttacctgac agaagaaata ttattctgac gagagataag
     1501 gggtttacct ttaatggttg tgaaattgtt cattcaatag aagatgtttt tgagttatgt
     1561 aaaaacgaag aagaaatttt tattttcgga ggagaacaga tttataattt gtttttccct
     1621 tatgttgaga aaatgtacat cacaaaaata catcatgaat tcgaaggaga tacttttttt
     1681 ccagaagtga attatgagga atggaatgag gtatttgccc aaaaagggat aaagaatgat
     1741 aaaaatccgt ataactacta ttttcatgta tatgaaagaa aaaacttatt gagttaacgg
     1801 gtgcgttaat tgaagaagaa cagtaaagat aaagcacaag agcttgggat tactccaagc
     1861 tctttttgtc atttgaaata aattatatct ttccaatcaa attgtttatc tgtaatccct
     1921 aatctttgag caggtgtcaa aaccttttta tccgctgatt taaaagggcg acaaaagttg
     1981 tagtaagttc ttagaattgt aatcgcaaat tgagcatact tcggattgaa gttagcgtaa
     2041 atatagctct tcttatcacc acgagctgtt gttaatggtc tttcaagaga tgatatataa
     2101 cgtcttatct gttgaataaa gctattggtc gaatggtcat taacatttaa tagcatcttt
     2161 gcgatttcgt ttggttccag agcagataaa tccgttctac aatcaactga ataaaatcct
     2221 ttatccttag tggctaatgg atgtttgata gggttatcgg catatttgcg atatctttct
     2281 ccatctttac taatagcctc ttcgtggaat tgatgacttg ttagtaattc agttagataa
     2341 tgagatgcca aagtccgtag aaactttgtt ttgaatcctc tgatatctcc ccaatcgagc
     2401 agttctgctt ttgcttgtcc gaattctttt aagcattgtt ttctgctttt cgtcttgtta
     2461 acttggcaaa taaaatgatg tgcatcgctc aaccttaatt ctttcgtgaa tactctataa
     2521 aaggcgtttc taatagagaa gtcatcatca ctaatcattc gccattcgtc ggcattaacc
     2581 atttgtttaa ttaaccaata gt
//
LOCUS       DACBYO010000188         2599 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.194, whole genome shotgun sequence.
ACCESSION   DACBYO010000188 DACBYO010000000
VERSION     DACBYO010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.194"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(70..660)
                     /locus_tag="IVD26_002955"
     CDS             complement(70..660)
                     /locus_tag="IVD26_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAP6080850.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            1144..1371
                     /locus_tag="IVD26_002956"
     CDS             1144..1371
                     /locus_tag="IVD26_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAP6080851.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            1387..2553
                     /locus_tag="IVD26_002957"
     CDS             1387..2553
                     /locus_tag="IVD26_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAP6080852.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
BASE COUNT          880 a          428 c          502 g          789 t
ORIGIN      
        1 gtgacaaata atcatcagta aaattacttg tcacactatt gataaggagt atttaattga
       61 agagaatgat taggagaaag gatctccgta ctttttatag taatcataga atccaagttt
      121 gtatagacga atcgtttttt ctcttatttc ttctgtttca aaatggactg cttgaagaat
      181 caagtctgtg aattctatag gagctgttcc attcgcagta atcaaattac gatctttcac
      241 agcttgttgt tctataaaat cttctttatt ctgataattt tccgattcta accaaggaaa
      301 ttgcgcattt ccggtgtgtt tgtaaccttg caataatccg ctctgagcta aataatcaac
      361 tgccccacaa atagcagcta ctggtacgtc tgtttttaac aatttatcga ttatttgata
      421 taaatgatga ttttttatgt cccatgaatt gccaccgatc ataataaaaa ggtcaacttt
      481 ttcaggtatt tgttcgatta agtaatcgat ttttgttttt aatcctccaa tggaagtgac
      541 ctctgattgg atagaagcag ttttgttttg ccatttctca ttttggttta gtgtgctagt
      601 aatataagca ccttcccaat cggcatattc ctctaataga aacgtaatcg cagttttcat
      661 tttcaagctc tcctttacta tctataacaa ggacaacagt tttaacctac agacattcat
      721 taaaattggg tagcgacagc gaaaacaaca attcttaagt tttagacaga gtatacagat
      781 agtcaactta attaaatacg aactaaataa aaatgacagg taatcatttt tgtttaccag
      841 cattataaca ttttgcatac atggatgaca aaagaaccaa ttcccacttg cttgagtaca
      901 atattaaaag aaactggaag gcaaaaagta attatagaaa cgaaaaataa atcatatcgg
      961 gcactcagac atgaaaacaa ccctagagat atataactag gtaaccagtt taatgaaaga
     1021 aaaaatcatc caagaagtcg attcttggat tttttagtgg atttgttcgc caaatacgtt
     1081 tagtatgcgt atatgagagg ttgtaagcaa agcgttgtgg tctgagcact taaggaggaa
     1141 tctgtgaaaa tagcttttca tatttttgca gattttgact taatgccgaa ggtcagcttt
     1201 gcgattaccg tttatcgaga ggctgtaaaa gcaccgtgta gctccgatga caataagcaa
     1261 gcatttttag agctaggttt ccttgattct aaatatgcgg cttatttcaa tgagttggtg
     1321 cttgaacgcg attttaagaa ggtcgaaaac aggcacgact tttcgacgta aggagaaaga
     1381 atttcaatga tagaaacaat aaatcccgca gaaaacaagg tttctgcgta cattcatatc
     1441 ccattttgcg agcatatctg ctattactgt gattttaata aagttttttt agaagggcag
     1501 ccagtagatg agtatgtgga aatgctgctg aatgaaatga aaataatgct agaaagtcat
     1561 ccgacagcga atttagaaac actttacgta gggggcggga caccaacttc tttatctgct
     1621 aaacaacttg atcgactgtt atcaggtgct agagagatcc tgccttttca aaatggtaat
     1681 gagtttactg tagaagcgaa tccaggtgat ttgacccgtg aaaaacttca agtaatgaaa
     1741 aactatggcg tcaatcgttt atccatggga gtgcagacat ttgataatcg cttattgaaa
     1801 aaaattggac gtaaacacac cgcagaagat gtgtatcaaa ctatgcaatt tttagaagca
     1861 gaaaatttta ccaatgtaag catcgatttg atttatgcat taccgggaca aacactagaa
     1921 ggatatctgg atactttgga aaaagctttg gctttggatc tgcctcacta ttctttgtac
     1981 tcattgatcc tcgaaaacaa aacaatgttc atgaactggg tacgacaagg aagactcgaa
     2041 ctgcctgatc aggaaacgga aaccagaatg tttgaagaga cgattgaagc aatggaaaag
     2101 catggacgtc accaatatga aataagtaac tttgggctct ccggacatga atctcaacat
     2161 aacctcatgt actggaacaa tgaccactat tttgggtttg gagctggtgc tagcggttat
     2221 cttggagata ttcgttaccg caacaaagga ccaatccaac actatttacg cccattacga
     2281 gcaaatgaac gcccggtatt ggaagaagaa aaattgacac gaaaaaatca aatagaagaa
     2341 gaaatgttct taggactaag aaaaaaaaca gggattacta aaaaacattt ctatgatcgc
     2401 tatcaaaaaa caattgaatc ggtgtacggt gatgtgctaa gggaattaga gcaagaaggg
     2461 ttacttgtta atgaagaaga ccgtgtttat ttgacaccaa gagggacctt tttggggaac
     2521 aatgtgtttg agcgcttttt gtttgaaaaa tagtttaaag aatatttgtt ttttatctga
     2581 atttaaataa aaaaagttc
//
LOCUS       DACBYO010000189         2532 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.195, whole genome shotgun sequence.
ACCESSION   DACBYO010000189 DACBYO010000000
VERSION     DACBYO010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.195"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            23..898
                     /locus_tag="IVD26_002958"
     CDS             23..898
                     /locus_tag="IVD26_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6080853.1"
                     /translation="MKPNPVETGKRIKSIRFNFGMTMEQFADLIGNAQKGNINNWERG
                     FSLPNKERLIKIAELSNKTIDWIKWGTLEEYIASYLKDSGYELYIKDFPEIPHKVFND
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDLGLTDDNKNVKMI
                     GQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAEIGGVSEL
                     YLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKIDDPDKREI
                     SLNAICQLSLLDKMG"
     gene            947..2329
                     /locus_tag="IVD26_002959"
     CDS             947..2329
                     /locus_tag="IVD26_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6080854.1"
                     /translation="MKPNLSLTSERIRKIIESKGLTLERFGDLIGDTPISSVNNWLRG
                     VSLPNKNRLLTIANIGNTSVDWIKWGTLEEYIASYLIDSGYELYIKDFPEIPYKVFKD
                     IQEKYSDTFSLDKDYELLNPIIKFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTT
                     LTNYYRGERNPRNTETWNILADYFHVPVSYLMGLDETNVELKNLNIGNNIKNIRKSKN
                     MTQTDFAELMGLSRSYIGDLENNRSNPSIKTLEAIARALDVPIVALINDSSTDNIVEP
                     YESLTAENILLKQENEELKYEVESLRKRLYEIQQVVNQGAEKMIPNLKDVSKRIKYIR
                     KKLGMTMEQFGSHLSNSPKSTIATWESGRNIPSQKKLQLIAIVGETTTDWIKWGTLEE
                     YITSYLIGIGYELYIKDFPEIPHKVFKDIQEKYSDTFSLDKDYELLDSIIKNIFTKYY
                     SKEFEVTQIP"
     gene            2343..>2532
                     /locus_tag="IVD26_002960"
     CDS             2343..>2532
                     /locus_tag="IVD26_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6080855.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNST"
BASE COUNT         1004 a          370 c          439 g          719 t
ORIGIN      
        1 attccataag agaggtgatt gtatgaaacc aaatcctgtt gaaacaggta aaagaattaa
       61 atcaattcgt tttaattttg gaatgactat ggaacaattt gcagatttaa ttggaaatgc
      121 tcaaaaagga aatattaaca attgggaacg aggattctcc cttcccaaca aagaaagatt
      181 aattaaaatt gctgaattaa gtaacaaaac tatcgactgg attaaatggg gaactttgga
      241 agaatacata gcttcatacc ttaaagattc agggtatgaa ctatatatta aagacttccc
      301 agagatacct cacaaagtct ttaatgacat tcaagaaaga tatagtaata cgttttcgct
      361 aaataaagac tatgagttat tgaatcctat aataaaaaat atatttacaa aatattactc
      421 aaaagatttt gaagattatc gagacataga agtcaaacca gatttaggac tgactgatga
      481 caacaaaaat gttaaaatga ttggacaacg tataaggaaa ataagaaaaa aagagaatat
      541 tacattagaa gaattcggca aactattctc tcctacagct gataaagctg ttataagcaa
      601 ctgggaaaat ggtaaaaacc ttcctaactc agaaagaatt aaaaagattg cagaaattgg
      661 cggagtttct gaactttatc ttatgacggg tgtcgattca agcgtagcag aatcaatgta
      721 ttttctatct gaagtagcat tggatgcttt ggaacgtctg tcaattgagg aagtcaatag
      781 aataattgaa agcttcgccg gttatcttaa tgtgatttca aaaattgatg atccagataa
      841 gcgagaaata tctctcaatg ctatttgtca actatcactt ctcgataaaa tgggttgatt
      901 cacaaaaaat attgaaagat tactttactc acgaggaggc ttagctatga aacctaatct
      961 atcgttaact agtgaacgta ttagaaaaat tatcgaatcc aaaggtctga cattagaacg
     1021 attcggtgat ttaattggcg acacaccaat aagttctgtt aataattggc ttagaggcgt
     1081 gtctttaccc aataaaaata ggcttttaac aattgcaaat attggaaaca ctagtgtaga
     1141 ctggattaaa tggggaactt tggaagaata catagcttca taccttatag attcaggtta
     1201 tgagctatat attaaagact ttccagagat accttacaaa gtctttaaag acattcaaga
     1261 aaaatatagt gatacgtttt cactagataa agactatgag ttattgaatc ctataataaa
     1321 atttactata gggggcgtta ctttgaatag aataaaattt tatattgatt ccagtaaaaa
     1381 gaccattaaa caaattagta cagaaactgg tattaactat acaactctta cgaactatta
     1441 ccgtggtgag cgaaatccta gaaatactga aacatggaat atccttgctg attatttcca
     1501 tgttcctgta agttatttga tgggattaga cgaaacaaat gttgaactca aaaaccttaa
     1561 tattggaaac aacatcaaaa atattagaaa aagtaaaaat atgacacaaa ctgattttgc
     1621 tgagttaatg ggtctatcac gatcatatat aggggattta gaaaataaca ggagtaaccc
     1681 cagtataaaa acactggaag ctattgcaag agcattggac gttccgatag tagcattaat
     1741 caacgattct tctactgata atatagtaga gccgtatgaa agtttgacag ccgaaaatat
     1801 ccttcttaaa caagaaaatg aggaattaaa atatgaggta gaaagcttac gaaaaagatt
     1861 gtatgaaatc caacaagtag taaatcaagg agctgaaaaa atgattccca atctaaaaga
     1921 cgtaagtaaa agaatcaaat atatcagaaa aaaattaggt atgactatgg agcaatttgg
     1981 ttctcattta agcaactcac ctaaaagtac aattgctact tgggaaagtg gtagaaatat
     2041 accttctcag aaaaagttac agctgattgc tatagtagga gaaaccacca ctgactggat
     2101 taaatgggga actttagaag agtatataac ttcatacctt atcggtatag gatatgagct
     2161 atatattaaa gactttccag agatacctca caaagtcttt aaagacattc aagaaaaata
     2221 tagtgatacg ttttcgttag ataaagacta tgaattattg gattctataa taaaaaatat
     2281 atttacaaaa tattactcaa aagaatttga agtaacccaa attccataag agaggtgatt
     2341 gtatgaagcc aaatccttca gaagcaggaa aacgaatcaa acaattacgc ctttcatgtg
     2401 gttttactat ggaagaactt ggaaggaaaa tagataattc accacgtgcg accatatcca
     2461 actgggaacg tgggaccaat ttaccaaatc cacaaaagct gaaattatta tcaactatca
     2521 ctaattcaac aa
//
LOCUS       DACBYO010000190         2468 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.197, whole genome shotgun sequence.
ACCESSION   DACBYO010000190 DACBYO010000000
VERSION     DACBYO010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.197"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(128..700)
                     /locus_tag="IVD26_002961"
     CDS             complement(128..700)
                     /locus_tag="IVD26_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP6080856.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(707..1369)
                     /gene="rpe"
                     /locus_tag="IVD26_002962"
     CDS             complement(707..1369)
                     /gene="rpe"
                     /locus_tag="IVD26_002962"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAP6080857.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            complement(1385..1900)
                     /locus_tag="IVD26_002963"
     CDS             complement(1385..1900)
                     /locus_tag="IVD26_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HAP6080858.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            complement(1902..2186)
                     /locus_tag="IVD26_002964"
     CDS             complement(1902..2186)
                     /locus_tag="IVD26_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP6080859.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            complement(2220..>2468)
                     /locus_tag="IVD26_002965"
     CDS             complement(2220..>2468)
                     /locus_tag="IVD26_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAP6080860.1"
                     /translation="GCSLYVVTTLYMATWLAPIITDVFTLASFDVGTAGLVTMLLCGL
                     WPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
BASE COUNT          762 a          492 c          350 g          864 t
ORIGIN      
        1 cattctatga cacgcttacg ctcaaaacta ctgaattatt aagttatgtc taatcaaata
       61 aaaaaaccat tctcatattt gctgaataat tagcatttag agaatggttt tttatcttta
      121 aaatctacta ctcaaaatct gcatgtcgag caaacatcgt ttctgagctt tcacctgttt
      181 tatccattaa agataacact aaactatcaa aggtgagaaa tgctaattgt tcaaaacttg
      241 aacccatagg ttgtgaaaaa gtatcttctt ctcgttgatt ttcatctttg gtaatacctg
      301 gtaatacaag aacagaatct gctaattgac caatcgacga gtcttttttc atggtaacta
      361 aagcaatgct tacaccactt tgatttgctt tggccgctaa attttttaaa ctacctgttt
      421 cacctgagcc agaacagata attaataaat ctccaggttg cgaatgtggt gaactaattt
      481 caccgacaag gctgactgaa aaacctaaat gcattaagcg attcgtaaat gcttgcatgg
      541 caattccaga gcgtcctgca ccagctagaa agatgtgttt agcttgaaca attttctcac
      601 taaattgttc taactctaca gaattaatac gttttgagtt attttgtaat tctaagataa
      661 tcgcttctaa atagttttta ttttggtctt tattggtcat gatcttttac ttcacttcct
      721 ctaatgattg atttagttta tcaatttgtt cttgcggggt atttttccca ttgaagatga
      781 aaccgcctga tacaaaaata tccgcccctg ctttagaaca aactttaatc gtttgattat
      841 caatcttgcc atctacttca atatcatacg tataatcatt ttgtttgcgt attacatcta
      901 actgttcgat tttaactact gtctcttgaa taaaatgctt attctctgtt cctggattga
      961 ttgtcattac taatacttga tcgactaaag ataatactgg ttcaataaaa ctgactggtg
     1021 ttgcaggatt aaaagtaatc cctacttttg ctcctgcttc cttgactaac tgaatgacct
     1081 tcattgcgtg tttggtagct tcaatgtgga aggtaacaat atctgctcct gcttctacaa
     1141 atcttgtgac aattttttct ggtgtatcaa tcatcaaatg aacatcaaac acaacgtctg
     1201 ttagtggacg aatatcttta ataacacttg gtccaaaagc catatctggt acaaaacagc
     1261 catccattac atcaatatgc aaataatcaa cattcttttc ttttaagatt tcaaataact
     1321 ctttaacttc tgcgataggt gcatttaaca atgatggagc aattgtcatt ctctattccc
     1381 ccgtttattc tcccataatc atgagattga ttgttctagt tcgctctctt agttgatccc
     1441 aatcgacaaa atagacacgg cccatttctc ctaataaaag tttaccttct tgaacaatta
     1501 aagtcattga gttggttcca taaatagatg aacgtaaatg tgcatcggta tttagcatga
     1561 cccatttttc tgcagggtaa ttgggatcag ataatcttgt tccaaaatca atgtgttttg
     1621 gccccggact gttgtattga ttttcactcg tcatttttgg aataatcgtt tccattacat
     1681 tgttgatgtc tacatgtaaa taatcatcac caaaaaagtt tgtgtcatgc atcgtttctt
     1741 caaaaaagag tgagcaagtt gtatgcgggc tcgaaattac taacattcca ttctcaatac
     1801 ctgctgtatc aactgtatct aaaagttctt ttcgaatatc atgatacgaa ggacgccctg
     1861 aaactgtttc aatagtcaaa gtgtcatgat gaaaacgcat attaaacacc taatctttct
     1921 tttacatctg cataaatggc atctgtacca atacctgtta ataagcccaa gccattcgtt
     1981 actttagctt taattacatc agggacaatt gttgtactta ctacagcatc atattcatca
     2041 attttattta gctcatcagc aattttagat tgataaattt tcacttgatc tgttaatcct
     2101 tcttcttcca accattttga taattttgct actgcaattg tagaagtagc atgacctgct
     2161 ccacaaataa ctaataattt tttcatattg atctcttctt tcttatttta attttatgat
     2221 taagctttct tcactttgtt catgtagata gaagcaccta ctaaaacaac tcctaatcca
     2281 cctattccaa ttacaccaaa gtaagatgct aataaaacaa acaaccctac tggccataat
     2341 ccacataaca acatagttac taatcctgct gtccccacat cgaaacttgc taatgtaaac
     2401 acatcagtga taattggtgc caaccatgtt gccatatata atgttgtaac aacatacaac
     2461 gaacatcc
//
LOCUS       DACBYO010000191         2398 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.199, whole genome shotgun sequence.
ACCESSION   DACBYO010000191 DACBYO010000000
VERSION     DACBYO010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.199"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            207..2069
                     /locus_tag="IVD26_002966"
     CDS             207..2069
                     /locus_tag="IVD26_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6080861.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="IVD26_002967"
     CDS             2069..>2398
                     /locus_tag="IVD26_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6080862.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DACBYO010000192         2353 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.200, whole genome shotgun sequence.
ACCESSION   DACBYO010000192 DACBYO010000000
VERSION     DACBYO010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2353
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.200"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..486
                     /locus_tag="IVD26_002968"
     CDS             <1..486
                     /locus_tag="IVD26_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP6080863.1"
                     /translation="LKEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKE
                     QQVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFS
                     NNQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVI
                     K"
     gene            complement(693..1094)
                     /locus_tag="IVD26_002969"
     CDS             complement(693..1094)
                     /locus_tag="IVD26_002969"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080864.1"
                     /translation="MSDKFSKKISSDIKEDFKAIFKTASIELAGERKQLIMDKYGEDK
                     KVATACKILDEGFEDAMQVMVLPENIRQRLRTTNVLERLNEEVRRRERVVRIFPNCDS
                     VIRIIGALLMEKDDEWTSAPRKYLEFDRNEI"
     gene            complement(1215..1298)
                     /locus_tag="IVD26_002970"
                     /pseudo
     CDS             complement(1215..1298)
                     /locus_tag="IVD26_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            1321..>2353
                     /locus_tag="IVD26_002971"
     CDS             1321..>2353
                     /locus_tag="IVD26_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP6080865.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKSFTEEVTSFKERELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERG
                     VKNVLLFITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKKAALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIE
                     SFNKQIKKYS"
BASE COUNT          735 a          477 c          481 g          660 t
ORIGIN      
        1 ttaaaggaag cgatcgatca aatcaagacg gctgtcttgt atcctcataa cggattaccg
       61 attttattga tgggtgtaag cggttcagga aaaacctttt tggcagaaaa aatttatgaa
      121 tacgccaagg aacaacaggt gatagaatca aatgctccat ttatcgccta taattgtgct
      181 caatacttta atttctcgat taacaagatc gtagaaaatt taacgatcct tgatgcaatg
      241 aaggttttga gattggtaca aaaggccgtc aaagaactcg aaaaactaat ggggatcgaa
      301 ttttcaaaca atcaattgtt cttgctttac atgcactgct gctcaatgat cgaacgtatt
      361 ttacgcaaag aaagtgtaga tgaacaagca gatatcaaag aatatattca aaaagaggga
      421 cataattatg aaatatcaaa atacccggct tacaaaacga agtttgaaag tactgtaata
      481 aagtaagatt taaataagca taaacaaggt aagaaccata ggggctgtgt caagtccaaa
      541 atcttgtgta aaaaggaaat ctcaaagtac gatgttttgc cttgttgagc ctagctacgg
      601 tccaatatgc tggtaagaag tgtcaagagc aaaaagcgaa gcgtctcttg atacttctca
      661 ccagtatatt atactattgg cggcttaatg tgctaaatct cgttacgatc aaattcaaga
      721 tattttctag gtgcagaagt ccattcgtca tccttttcca tcaataaagc accgatgata
      781 cgaataacag aatcacaatt tgggaaaatt cggacaacac gttcacgacg gcgtacttct
      841 tcatttagtc tttcaagaac attcgttgtt ctcaatcgtt gacggatatt ttctggtaaa
      901 accattactt gcatggcatc ttcgaagccc tcatccaata ttttacaggc agttgcgact
      961 ttcttgtctt ccccatattt atccataata agttgtttac gttctccagc cagctcgatg
     1021 cttgccgttt tgaagatggc tttaaagtct tctttgatat cgcttgagat tttcttggag
     1081 aatttgtcgg aaatgttgcg aaggagatgt gcttggcatc tctgctagct cgcacaaaga
     1141 aggtattctt tcacagcttt tgtgagccct atatgcgcat ccgagatgac catctttact
     1201 cctgaaagac cgcgttcttt caatccgaga gtgtaaaata ttttgtgtaa atagaaaaaa
     1261 ggaagtccct tcagtagaat agagttacca caacacattc acagaaaaga ggacttccat
     1321 atgaacgatt ttactacaga aattctaaag actctagcga ataaaggcga tttgaatgaa
     1381 ttattccgtg tccatttgga aaaagctgtc aatacgcttc tcaaaacgga gttaacggct
     1441 ttcctcgatt acgaaaagta cgatcgcatt ggttttaaca cgggtaattc tcgtaacggc
     1501 tcctatgacc gtacggtcaa gaccgagtac ggggaacttc atctccagat tccgcgcgac
     1561 cgcaacggcg agttcaagca acagactgtt cctgcttata gacggacgaa tgatacctta
     1621 gaggagaccg tcattcacct cttccgaaaa ggtattacca tgtcggaaat cgcagacttg
     1681 attgagaaaa tgtatgggca tcactacacg ccccaaacca tgtccaatat gactaaatca
     1741 tttacggaag aagtcacttc atttaaggaa cgtgagcttc atgaccgtta tgccgctatt
     1801 tatatggacg caacctatat ccctttaaag cggaaaaccg tcgccaagga agccattcat
     1861 atcgcagttg gcattcgccc ggacggttca aaggaagtgt tgagctatgc gattgcacca
     1921 actgaatcta tcacgatttg ggaagagatt ttaatagacc tccaggaacg tggcgtgaaa
     1981 aacgtcctcc ttttcatcac ggatggctta aaggggatgg caggggccgt gcagcggttc
     2041 taccccaaag cccgttttca acattgctgt gtgcacgttt cccgtaatat cagtcacaaa
     2101 gtgcgtgtcg atgatcgtaa ggaagtctgt gatgatttta aaatggtgta tcaagcgtca
     2161 tctaaaaagg cggcattgga agcacgtggt gcttttgcgg aaaaatggaa aaccagttat
     2221 ccaaaaatgg tggaatcgat cctttcgaac gattacctgc tcactttcta tgattttcca
     2281 ttagccatac gcaagactat ttactctacg aacttgattg aatcctttaa taagcaaatc
     2341 aagaaataca gcc
//
LOCUS       DACBYO010000193         2344 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.201, whole genome shotgun sequence.
ACCESSION   DACBYO010000193 DACBYO010000000
VERSION     DACBYO010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2344
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.201"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(116..397)
                     /locus_tag="IVD26_002972"
                     /pseudo
     CDS             complement(116..397)
                     /locus_tag="IVD26_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            859..2241
                     /locus_tag="IVD26_002973"
                     /pseudo
     CDS             859..2241
                     /locus_tag="IVD26_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          853 a          398 c          389 g          704 t
ORIGIN      
        1 aatgacgtct tttttgaatt gtttgccttt aaaatgattc attactctgt cctctctgtc
       61 ttttttctca attttacact aaaatagatt ttttggaaaa ctttgcaaca gaaccgaaat
      121 gagtatagta tgaattagta atttggtttt catctaagtt tagctttgat ttactaaaat
      181 tgatatctcg atacatgttc aatacatcta atacaaatcg agaatcttct ttcggaaatg
      241 gctcagaaag atcactccaa atttcatcat cataatgata ctcgtaacct tctctcaata
      301 tttcgatttt tctttcataa taagatctgt tttggtcctc aaatttagcc aataactcaa
      361 attgatttac tagtgacaat ctctgaaaac tgtccattaa atgtttcttc ctatcttgtt
      421 cattaacaaa aaattataag cccttacaac gaatattata tattaaattt aattgtaggt
      481 gaacacgaat tttataaata tttatggtgt taatgacaaa tgatatccga ctcctcttca
      541 tacgttctgg actatttgct aatagattaa aatttcagca tctatttctg accataaata
      601 aatgagctgc cgaaaagctg ccaaatcaga cttgaaaata aaggatcaaa aacttttaag
      661 tttctgaccc cgtaactcac acttcaaaat cttacttaaa aaggagtctg aaagaaaaaa
      721 agagtattca aaattttttt ctaactagct acatcacatc tatgcattga cactcaaaga
      781 accagaataa gtcatcagaa agcaaggggg tgcggacata atcctggacg aaaaaataaa
      841 cttaggagga atgtccgtgt gttttcccac aaagagcgtg taagggcaat tcagttattt
      901 ttaaaatacg attgctctta tgctgcaacc attcgagaat tagggtatcc gtcgattggt
      961 gcactacgga aatggtataa agagtatttg gaatccggag agctccatca ggagcaccga
     1021 aaaaaatcaa agtattctga agaacaaaaa cgaatagcgg tgaatcatta ttttgaatat
     1081 ggtcaatgtt atgcacgaac cattcgcatg cttggttatc ctaatagaga gtccttgcgg
     1141 cagcggtgtg aagaacttgc accaggagct agaaaactcc gaaaaagtgc ggtaaagtta
     1201 acacaagatc aaaaagaagc tgtgttgaaa aaattctata aaccgcaaac taataggaaa
     1261 aatttagccg aatctggagg aattagtaga gttactctat atcaatggaa aaacacggtt
     1321 cttggaaagg attttccatt gtgtatgact ttaaaaaatc aggaaaaaca aaaagagcta
     1381 cttttaaagg aagtagaaga cttacaaaaa caagtacacc aattacagct cgaaaaagca
     1441 ttactcgaag gagcggctga actgctaaaa aaagaaaaag gcgtcaatct tctttgtcta
     1501 tcaaatcaag aaaaaacgat attgattgat gccttacgaa atcagttcac cttgaaagag
     1561 cttcttcaac agctccagtt tcctaaaagc agctattttt atcaaaaaca agcacttgag
     1621 aaaccagata agtattacaa agaacgtcaa attaattatc acgattttca atcataactt
     1681 ctgtgcgtat ggttaccgta gaattcacca agctttaaaa aatatgggta aaaagctttc
     1741 tgaaaaagtt gtacgtagat tgatgactga ggaaaatcta tttgttaaat tttctagacg
     1801 aaaaaagtat tcttcgtatg ctggggaaat ttctcctgca caccccaatt tattaaatcg
     1861 gaattttaaa gcaaagaagc caaatgaaaa atggttaaca gatattactg aatttagaat
     1921 tctcgcaggg aaaatctact tatcaccact tgtcgattgt tacgatggtg ctattgttag
     1981 ttggactatt ggaacaaagc caacttgctt cactctatgt ctaaaaagag ttattcacca
     2041 gataattcag cgtgcgaagg tttctttgga cgattaaaaa acgagatgtt ttatcaacgt
     2101 gactggaaga atacaacaat caatcagttt ataaacaaat tggatgatta tattcattgg
     2161 tataataatc aacgaattaa gttatcttta ggaaggctaa gccctcttca atatcggaag
     2221 aagcaaagat atatttgtta aaaaggtcca aaaaaaatat ccgcaccccc tttttttgta
     2281 aaaaactatt gcacaataca agtagcctac ggctatcgaa atttccataa ctttcgagca
     2341 agaa
//
LOCUS       DACBYO010000194         2269 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.203, whole genome shotgun sequence.
ACCESSION   DACBYO010000194 DACBYO010000000
VERSION     DACBYO010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.203"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            190..444
                     /locus_tag="IVD26_002974"
     CDS             190..444
                     /locus_tag="IVD26_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP6080866.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            445..762
                     /locus_tag="IVD26_002975"
     CDS             445..762
                     /locus_tag="IVD26_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP6080867.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1321..2256
                     /locus_tag="IVD26_002976"
     CDS             1321..2256
                     /locus_tag="IVD26_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080868.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          823 a          307 c          428 g          711 t
ORIGIN      
        1 atgttaacgg aagtgtatgg tgagtagttc actcgtattt tgatatcgtt tgtatatgtt
       61 ttcagcgttc taagtggctt attttgtcca ataataatat ggagtggaat cccttaagaa
      121 acaccgttgg caattgttgt tataacatgt tataatttat tcatcaaaaa ctaaaaggag
      181 tgtgataaca tgggaaaaga actaaaggtt agaaagatcg gcaatagcgt gggagtgatc
      241 cttccaagct ctcttggatt aaaaagcgga gacattatcc aagccaaaca agaaggcaac
      301 ttattcatat tagatactac tcaaatagca aaagaacacg atcgcaaatt gattgaagaa
      361 agtttccaag actttgagaa aggtttaaca gtttcagaaa ttgaaatggt aaaagctttc
      421 ggaaaatacg gctggagtga atagatgaaa gagtacacgc tagtttattc taaaagtttt
      481 cagaccagcc ttgaaacgat aatagaagaa tgggaaaatg agcttgctct ttctccagcc
      541 agcataaaaa gatttgtagg tgcgatccag aaggctttag aactaaccaa aaattttcca
      601 actatgcatg aggaagtttc cgaaatctat ggaatggata tcccaacata tcggatcgtg
      661 atcggcaaaa gctatgcctt attttatcgg atcgaccatg aaaaaaaaga gatacttgta
      721 ggacgtattt tccaatctaa acaaatgaaa ctaggctttt aacaataatt aggaaaaagt
      781 cgctcatcct ctacaggtgg gtgattaatg ccgctcgata tggttgttaa ccgtcggtta
      841 ctcgaagatt gatatataag acttagtacc tttttatttt gctccatgtt atggccgaag
      901 gtctaaagat acaatcatta gtctagagaa aaattaagaa ccgtaggaac tacggggatc
      961 gcttggtgaa taagagacac tgctattagt gaaaaaataa gatatcaagt acgctctatt
     1021 cccaaaaatt tcgtgacttt actcatgaga ggttcaagta gtatattttt aatcaaaatt
     1081 gacgtaactt ttaataaata ctacctaaat aaggtagtat ttatttttgt gttttaaaag
     1141 aggaagtcca atatatctat gggaaacttc ttaaatatta tgttggtaca tgaaaatata
     1201 catccctgct agactattta caacatttta ctttgtacgt attcttgttt taaaaggaat
     1261 gggataaaat ataggtacaa taactatttg atgctaaata taattaatgg aggagagata
     1321 gtgaacatac ttaatgaaaa aagatatgta tggtttgctg gtaaaaaata tattactact
     1381 ttcaaaagat tatccgagtt aatgcagcag actgttaaaa gtgctatgcc tgaaggatac
     1441 aagtttaatt ttgttcaatc ttcagtatct actgaaagta tctatttttc aattctttct
     1501 gagagtaggc tttttcattt tagaataagt tctcatgtaa agaaaactga tgttgatata
     1561 tatacgttcc gtacaaataa ttataaaaat ttaaatgatt tgagtagaag tatcagtgaa
     1621 tatctcaagg ggaatagcta tctcaagatt cgattttcac atatattaat tttactacca
     1681 tatttgaatg agaatttcac cctaattcaa gtagataagt ctttcattgc ctcaggtaat
     1741 caaggaaata tgaatattac aagtaacaaa acgtcacgtg tgctattggc gttgatgggt
     1801 tacggaattc tttatagaga tgaccaaaat ggccagattc taataaatcg ggctgggcgt
     1861 tcattattaa tgaaatatag aaaatttata ccggaagatt ttcaaaactt acagttagaa
     1921 aacatgcgtt tagaagattt atttagatta gcagaagatg ataagtatag atttgaagtt
     1981 ttgaaaattc aaaagaatga actattgaat aagttatatc ctgagaatgc gataaaagca
     2041 cattttggtg atgctaatca tatgtatagt tggttcattc ctaaaagatt tagagggaaa
     2101 atcaatgctg gagatcaagt gaaagtactc aatcgaaata gtacagatgt cgtaatgata
     2161 acagatatct atgtagaaga tgaagatata atcaaatata tgaagcctgt gataaaactt
     2221 gttaataaaa ataaaggaac ccgtggtgct agttaatttt ttcctagag
//
LOCUS       DACBYO010000195         2252 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.204, whole genome shotgun sequence.
ACCESSION   DACBYO010000195 DACBYO010000000
VERSION     DACBYO010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.204"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(151..2148)
                     /locus_tag="IVD26_002977"
     CDS             complement(151..2148)
                     /locus_tag="IVD26_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAP6080869.1"
                     /translation="MIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKA
                     LVTNKANQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHL
                     KEATKRLSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVY
                     IKNSGVTDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADE
                     AEKYLAKGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGS
                     NLMLSMNAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHE
                     QGSKEITENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKS
                     SVFNRSGQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRD
                     SFKEFGLGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYT
                     PIQLAQYASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMA
                     ILREGFHQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGP
                     TDNPEIAISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          574 a          504 c          411 g          763 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct ta
//
LOCUS       DACBYO010000196         2166 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.205, whole genome shotgun sequence.
ACCESSION   DACBYO010000196 DACBYO010000000
VERSION     DACBYO010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2166
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.205"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            125..526
                     /locus_tag="IVD26_002978"
     CDS             125..526
                     /locus_tag="IVD26_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAP6080870.1"
                     /translation="MNYSPSFQPDSVRTPEDFQRFLEREFYASNRPTIILSYSLSLGL
                     VLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESANLMLNVMGIGSMAAAVVGFIHFD
                     FILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            677..1843
                     /locus_tag="IVD26_002979"
     CDS             677..1843
                     /locus_tag="IVD26_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6080871.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            2073..>2166
                     /locus_tag="IVD26_002980"
     CDS             2073..>2166
                     /locus_tag="IVD26_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAP6080872.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNT"
BASE COUNT          738 a          350 c          399 g          679 t
ORIGIN      
        1 tgaaattttg gtaggtgtgt ctttatctga gaaacaacaa tccgatcatg gaacttttat
       61 tgattttgag aaggaacaat gggtgatcca acaaaaggat aaatctggta tacgccgcta
      121 tacgatgaat tatagcccat ctttccaacc agattctgta cgtacgcccg aagatttcca
      181 acgattttta gaaagagaat tttatgccag taatcgtcca acaatcattt tatcttatag
      241 tttaagtctt ggtcttgtcc tatttgtcat gacgagtctc attttattcg gggcttcctt
      301 tttcttgtgg atgacaagaa aaagccaact ttcatccatt catacattca aagagagtgc
      361 aaatttgatg ctgaatgtta tgggaatagg ttccatggca gcagcagttg tagggtttat
      421 ccactttgac tttatcttga tgctaagtgt ccaaacaacg ataactgtct tgctgctttt
      481 atgggttttt gtcaaaacaa gattcaaaga taagcgtgtc gaatgacaag tttaagcgat
      541 ttatgcgaca atgaatgtga aaaaaatgaa aaataaagta gtttttgaaa aatttctgaa
      601 aaaattaaac ttcttagttg attcttttct tttttagtat taacgtaata gggtagtttt
      661 tttaaggagg aaaatcatgt tagagaaaac tttatacaat caattatttt cacgttcttt
      721 ctcgctccct gtcgaagtaa attattggga cggtacaacg aaacaatacg gagatacgga
      781 cactcctccc caaatcaaaa tcaatatcca tgaagaaatc ccaatgaaag agattacaag
      841 taacgcttct ttggcactag gagaagccta tatggatcat cgaatcgaga tcgagggaag
      901 tatccaagca ttgatcaacg atgcttatca gcaagcaaac agctttttac gaggaaaaga
      961 ttatctaaaa tggctgccaa agaaagaaaa acatacgaaa caaaaaaaca aagaagatat
     1021 ccatgcgcat tatgacttag gtaacgactt ttataaactt tggctagatc caactttgac
     1081 ttattcttgt gcttatttca atacacctga agatacgttg gaacaagcac aaatcaataa
     1141 agtccatcat atcttagaca aactctttat caaagaaggc gaaacgttgc ttgatatcgg
     1201 ttgtggctgg ggaacattga tgttcactgc taccaaagag tataatgtca aggcaactgg
     1261 gatcacacta agtgaagaac aatacgattt gattaccaaa agaataaaag aagaacattt
     1321 agaagataaa tgccgtgtat tattaatgga ttaccgcgaa ctaaaaggcg aaacgtttga
     1381 tcatatcaca agtgtaggta tgttcgaaca tgtaggttct gaaaatcttg aaggttattt
     1441 caaagtggta aaagatttat tgaaaccaaa aggaacagct ttgatccatg gaatcagccg
     1501 acaacaaggc ggtgcgacaa atgcttggat caataaatat attttccctg gcggttatgt
     1561 ccctggtgtt actgaattag ttgataatat tacaaaaaac gatttgcaac tgattgattt
     1621 ggaaagctta cgtcgtgact accaattgac attagaacat tggacaaaga attttcatca
     1681 agtccaagat caagtcacga aagaaatggg tgattccttc tatcgaatgt gggatctata
     1741 tttacaagct tgtgcagctt catttgaatc aagtaatatc gatgtgattc aatatttgct
     1801 tgttcaacct ggaaacaatg acatcccaat gcatcgtgca taattgaggc aaaagtactg
     1861 tttaaagact atttaaaaag aagctaagtt ttatgatgct ccagaagtga acttttttgt
     1921 ctaacttcta ggattgtctc taaagcttag tttctttttc tttatatttt cataataaaa
     1981 gtttggttct ttaattttta aacatgacag aaaatttttt cttcgttata cttgtaatag
     2041 aatactattt tataacaaag gggatcgaat caatgaaaaa aactgttatt tatactagtt
     2101 tatttgcagc tttgttttta gctgcttgtc aatcaaatac caatcaaggc acatctggga
     2161 atacgt
//
LOCUS       DACBYO010000197         2091 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.206, whole genome shotgun sequence.
ACCESSION   DACBYO010000197 DACBYO010000000
VERSION     DACBYO010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.206"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..714)
                     /locus_tag="IVD26_002981"
     CDS             complement(<1..714)
                     /locus_tag="IVD26_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAP6080873.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGL"
     gene            1097..1180
                     /locus_tag="IVD26_002982"
     tRNA            1097..1180
                     /locus_tag="IVD26_002982"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Leu,seq:gag)
     gene            complement(1420..2091)
                     /locus_tag="IVD26_002983"
                     /pseudo
     CDS             complement(1420..2091)
                     /locus_tag="IVD26_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          695 a          423 c          322 g          651 t
ORIGIN      
        1 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
       61 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
      121 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
      181 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
      241 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
      301 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
      361 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
      421 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
      481 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
      541 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
      601 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
      661 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
      721 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
      781 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
      841 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
      901 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
      961 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     1021 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     1081 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     1141 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     1201 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     1261 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     1321 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     1381 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     1441 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     1501 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     1561 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     1621 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     1681 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     1741 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     1801 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     1861 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     1921 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     1981 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     2041 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat t
//
LOCUS       DACBYO010000198         2056 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.207, whole genome shotgun sequence.
ACCESSION   DACBYO010000198 DACBYO010000000
VERSION     DACBYO010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.207"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            493..714
                     /locus_tag="IVD26_002984"
     CDS             493..714
                     /locus_tag="IVD26_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080874.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="IVD26_002985"
     CDS             715..972
                     /locus_tag="IVD26_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080875.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKVAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="IVD26_002986"
     CDS             complement(1108..1710)
                     /locus_tag="IVD26_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP6080876.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKLRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="IVD26_002987"
     CDS             complement(1777..1932)
                     /locus_tag="IVD26_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010001600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6080877.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          462 c          314 g          602 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggtggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaag cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatta ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DACBYO010000199         2015 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.208, whole genome shotgun sequence.
ACCESSION   DACBYO010000199 DACBYO010000000
VERSION     DACBYO010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2015
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.208"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..755
                     /locus_tag="IVD26_002988"
     CDS             <1..755
                     /locus_tag="IVD26_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080878.1"
                     /translation="TANFAMEVHDLTFAMGVFFLYYVFFENKNTKKHKIKIIVSLILI
                     FMGLKRIELLALSGAILVYYVLLKWGKKIQIRALVCTICATVISLVFIYIIDTGILAL
                     LMSNLGITDDGARLSFYLYSSKFYELGLGYVGTGWTWFSKYFFNLYLSHFRLNGGRIA
                     ASLHSDILTIYIEVGCIVFIIWMFWLFFVKPIRLTKKFGLKTGECVLLLTIYMFILYL
                     TDNTLTYPDTQMIFLLVPMIVSWVDNQQRISE"
     gene            839..1927
                     /locus_tag="IVD26_002989"
     CDS             839..1927
                     /locus_tag="IVD26_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080879.1"
                     /translation="MKKILVLANTYYQIIVAIQMKNTIFSDEYVEIIISDHSKNTKEI
                     AKKIEEKKVFDGCHYLESKSFDDNIGYFQKIKDCLQISCGKSNRYAYYLKNCKSEYFD
                     EFICFSMGEVWLEGIYACLYRNNKNVQVSILEEGILSYGVDIIPTARTKAIAVLNYLK
                     KRTPLYNKSYNFYCFFPNIYTGRENTIQIPLVTAGSRTALQLSDIFNPMIDIYKEKKY
                     IFFTSVYDFEGGEPVGEYELVCKIADLVGKDNLIVKTHPRDVRTIYKDNGFIEDKNSS
                     IPWEAIQLSGDFNDKIFMTINSGSVISGSTMSAKPVRTYYMYKLCNIEGNPSCKKNAY
                     DIERLLKQKTMKNILKNVKIAESLDDIL"
BASE COUNT          738 a          214 c          352 g          711 t
ORIGIN      
        1 atactgcaaa ttttgctatg gaggtacatg atttaacttt tgcgatgggg gtttttttcc
       61 tttattacgt attttttgaa aataaaaata caaaaaaaca taagataaaa attatcgtat
      121 ctttaatttt aattttcatg ggattgaaga gaattgaact gttagcttta agtggtgcaa
      181 ttctagtgta ttatgtttta ttaaagtggg gaaaaaagat tcaaatccgt gcattagtgt
      241 gtactatttg tgcaactgtt atttcgttag tgtttattta cattatagat acaggaattt
      301 tggcattgct tatgtcaaat ttgggcatta cagatgacgg tgcaaggctt tcattttatc
      361 tatattcatc taaattttat gaacttggtt taggatatgt aggaacagga tggacatggt
      421 tttcaaaata cttttttaat ctttatttat cgcactttag gttaaatggt ggaagaattg
      481 cagcaagcct acacagtgat atattaacta tttatataga agttggatgt atagttttta
      541 ttatatggat gttttggtta ttttttgtga aaccgataag actaactaaa aaatttggat
      601 tgaaaacagg ggagtgtgta ttattattaa ctatatatat gtttatatta tatttgacgg
      661 ataatacgct cacttatcca gacactcaaa tgatttttct cttagtacct atgatagttt
      721 cgtgggttga taatcaacaa cgaatatcgg aatagatagc taaagtatat tttaattatg
      781 aatttataat tagttgtaaa agttaatatt taacggacag gaagtagggt gaaaaaattt
      841 gaaaaaaatt ttagtgttag caaatacata ttatcaaata atagtagcaa tacaaatgaa
      901 aaatacaatt ttttccgatg agtatgttga aattattatt tctgatcatt ctaaaaacac
      961 taaagaaatt gcgaaaaaaa tagaagaaaa aaaagtgttt gatggctgtc attatttaga
     1021 aagcaaatct tttgatgata atattgggta ttttcaaaag attaaggact gtcttcagat
     1081 ttcttgtggt aaatcaaatc gatatgccta ttatttgaaa aactgtaaaa gtgaatattt
     1141 tgatgaattt atttgttttt caatgggaga ggtttggttg gaaggaatat atgcttgctt
     1201 atatcgaaat aataaaaatg tacaggtatc aattttagaa gaaggtattt taagctatgg
     1261 agttgacatt attccaacag caagaacaaa agctatcgca gtactcaatt acttaaaaaa
     1321 aaggactcca ctatataaca aaagctataa tttttattgt ttttttccta atatatatac
     1381 aggaagagag aatacaatac aaattccatt agttacagct gggtcaagaa ccgcattgca
     1441 actttcggat atttttaacc ctatgataga tatttataaa gaaaaaaaat atatattttt
     1501 tacgtctgtt tatgattttg agggcggaga acctgtcgga gaatatgaat tagtatgcaa
     1561 aatagcagac ttagtaggaa aagataatct aattgttaag acgcatccta gagatgtaag
     1621 aacaatttat aaagataatg gatttatcga ggataaaaat tcatcaatac cttgggaggc
     1681 gattcaattg tcaggcgatt ttaacgataa aatatttatg acaattaatt caggaagtgt
     1741 tatttcaggt agtacaatgt ctgcaaaacc tgtacgcacg tattatatgt ataaattgtg
     1801 taacatagaa ggaaatccgt cttgcaaaaa gaatgcgtat gatattgagc gattgcttaa
     1861 gcaaaaaacg atgaaaaaca ttttaaagaa tgtgaaaata gcagaaagct tagatgatat
     1921 actatgagca aaactaaata tttaattaaa aatatgggaa tattaacaat aagtaatttt
     1981 tcttcaaaaa ttttagtttt tttgttagtc ccttt
//
LOCUS       DACBYO010000200         1997 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.209, whole genome shotgun sequence.
ACCESSION   DACBYO010000200 DACBYO010000000
VERSION     DACBYO010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1997
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.209"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..372
                     /locus_tag="IVD26_002990"
     CDS             <1..372
                     /locus_tag="IVD26_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAP6080880.1"
                     /translation="VSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFRRF
                     PEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTDDW
                     QKVMAAEVIATYLDGDLVYKK"
     gene            420..1820
                     /gene="yfcC"
                     /locus_tag="IVD26_002991"
     CDS             420..1820
                     /gene="yfcC"
                     /locus_tag="IVD26_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAP6080881.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1853..>1997
                     /locus_tag="IVD26_002992"
     CDS             1853..>1997
                     /locus_tag="IVD26_002992"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP6080882.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          550 a          339 c          432 g          676 t
ORIGIN      
        1 gtttccacag aggacttctt taattattgt cgattagagg aaagtggtgt aacagtcact
       61 agcggtacag atttaccgct gtttattact gatattcctg aatcgattat aagagcagta
      121 ttccgtcgtt ttcctgaagg agaagaagtc tgggagaaag aaacaagctt cacgacaacc
      181 gagctgctga aaagttttac aagcaacagc ttcaaagtaa atggtttatc ggagtacgga
      241 gaaataaaag tagggaaaag cgccagctta gctgttttca gcgaggacct ctgtactgat
      301 gactggcaaa aagtgatggc tgcggaagtt atcgctacct atcttgatgg tgacttagtt
      361 tacaagaaat aatgcttttc gatataacgt tataaaacga attaaagaga ggttaaaaaa
      421 tggaaacaat gaaaagaaaa ttcaccttcc cacatagtta tacattgatt tttatcttaa
      481 ttattttggc tgcaatttta acttggataa ttcctagtgg tcagtttgag acagttgttg
      541 aaaacgtcgc aggtatggaa aaaacaacgg ttgttccggg aacctatcac caaatcgata
      601 aggcagatta tggacaaggt ttttcctcta tactaatggc accagctgaa gggattattt
      661 cagctgttga ggttgttgct tttgttctca tcgttggtgg tgccttcggg attatcctaa
      721 aaacgggagc catcgatcga gggctgttta ccttagcaaa agttctggga gacaagggga
      781 tcttagttat tccgatgtcg atgattctat tcagcttagg aggatcaacc tttggcatga
      841 gcgaggaagt cattccctta tttgcggtgt ttatttctct gatgttttct cttggctatg
      901 attccatgac tgcgatcttg attctatttt taagtacaca agcgggatat gttgggtcga
      961 cgattaatcc cttcaacgtt ttaatcgcac agggagtagc tggcgtttac ggaaatcccc
     1021 tgctttggtt tcggatgcta tcctggattg tcattactgg gatttcaatt gttttcacca
     1081 tgctttatgc tagcagagtc aaaaagaatc cactgtcctc tattgtttat gagagtgatt
     1141 taaaggttaa gcataagttt caaaattttg acactgaaaa agagttttca acacaagata
     1201 aactaattat cgccggtttt atcgtaggtt taggaatcat gatttggggt atcatttcca
     1261 agggatggta tatggttgaa atttctgcac tattcttagg attaggtctt tttgctgggg
     1321 gcatcgctag attttctcaa aaggaaattg ctgaagcttt tgtcgaaggc tgttcagatt
     1381 tcgcctatgc tgctgtaatc attgggctag ctagaggagt cttggtaatc ttggaaggtg
     1441 gaatgattat tgacactatt ctaaacagct tggctaacct tttaggtggt cttccaaaat
     1501 tcctgttcac tacgattcta ctcatttctc aagtaattgt ttcctttttt gttccatcct
     1561 cctcaggagc tgcggcatta acgatgccgg ttatggcacc attgggtgat ctaatgaatg
     1621 taagtcgtga tgttgttgtt ctaagtaacc agtttggaaa tggtttaatg aatattatct
     1681 ccccaactag tggtgtatta ctggcaggat tagccatcgc agagattaat ttctctaaat
     1741 ggtttaaggt tggcttcaaa atatttgcca tcttaaccct tgtttctgct gttttgttat
     1801 acattgctac actcttttag tcttaatcat ccattaatag gaggcaatag ttatgattaa
     1861 aataaatcaa ttagcaggaa tgaatatcca ctatttattt tattctctca aagaattttt
     1921 cgcttatcaa cagaaaattg gtatttcttc tgttgaactt tggggaggtg ctccgcattt
     1981 tttcatagat gctttta
//
LOCUS       DACBYO010000201         1971 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.210, whole genome shotgun sequence.
ACCESSION   DACBYO010000201 DACBYO010000000
VERSION     DACBYO010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1971
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.210"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            267..497
                     /locus_tag="IVD26_002993"
     CDS             267..497
                     /locus_tag="IVD26_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080883.1"
                     /translation="MCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQKGYPYGPTN
                     LKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            511..843
                     /locus_tag="IVD26_002994"
     CDS             511..843
                     /locus_tag="IVD26_002994"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080884.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            888..1436
                     /locus_tag="IVD26_002995"
     CDS             888..1436
                     /locus_tag="IVD26_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP6080885.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            1443..1895
                     /locus_tag="IVD26_002996"
     CDS             1443..1895
                     /locus_tag="IVD26_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080886.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
BASE COUNT          707 a          207 c          404 g          653 t
ORIGIN      
        1 aagattgatg cgatcaagat ttattatgta cggagtgcgt attaaaataa aaaatgaaca
       61 ctcatattta ttatacaccg aagaaataga aaaaaacaga ctgttttttt aagaaaaact
      121 atgtcattct ttacttgaaa aaagttgtta taggacagaa aggataaaac aaaaacggaa
      181 aaaatatgtc ttatgaataa ctataagaac tattctattt tttaggagat ggatacgaga
      241 tgaaaaaact aattggctat agtgtgatgt gtattggatt tgttggtgtg ggattgtttg
      301 tatcgactga atctgcttct gcggctgaat ggtataatcc tatctggtat aatccgaaca
      361 ttgaatgtca aaaaggctat ccgtatggac cgacaaatct gaaaaatgga aaatgtagag
      421 taaattggaa tggcgttgta gatagtgtaa ttactggttc aatggactct gctctacatg
      481 gctttacggg tcactagaag gaggaagaaa atgtctgaag agaaaaaaga aatcgttgaa
      541 tcattagtag ctttaaaaga ttctctttct aagattgaat atgttgatag gcaagaaatt
      601 caaaaactaa ttgatgatac tattattgaa atccaagatg cgcgttgtga aggtataaaa
      661 atttctgtag ctttatctaa agtaatagaa aaaatgaacc gttcattagc gtttaatgga
      721 ttgaagctag atagacaaac tagtctgata tgggatcatt taaaagactt gtatgacaag
      781 tctaaaagaa gtgaacggac tgctgtatca atcttaaaag gcctttgggg aatgaattca
      841 taaacaagat atttaaaaag taacttattt tttatggagg agaaattatg aaaagaataa
      901 ttaaaatatt tggtgtttta ggtgttttct tattaggttt aagtactttt gttagtactg
      961 gaacaagtgt gtatgccaca gaaaaagtga atacagttga tttagaaata aagaataaat
     1021 tagtagatga attaactttt tattttgata cagttggttt tttagacgaa catggtgtat
     1081 accatataaa ggattttggt gctattcgtg aacgaatcag tcaagataac gaacaaggaa
     1141 gagcagcaag agtcttttat gaacatatta ttgttcctag aatggagaaa gttgattgga
     1201 aacgatatgc tggatgtgta gccattaatt ctcttcctgg aggaggagtg gcttgggcta
     1261 taggtacgca gggagatttt attgaagcat taaaagcttt taattttgaa aaagctgcgg
     1321 atttattatt aaaaattgca gaaaaacaat taggaaaagc tgcagctaaa gagttagcta
     1381 aggtaaatat tgtagcagga attgcagcag ctgctgctag ctgtgcatta gagtaaaagt
     1441 ttatgaaaag tttagaacaa gagcatatgg cttttaaaca agcaatgttt aaagaaaata
     1501 tctatttaaa ccataactat attcgtgttt ctaaggcatg ttcaccagta ttgaatatgc
     1561 ttggaggtgg aaatggatta tatcatttac tgtttgtcga tgtttgttgg ttaatttttt
     1621 taccagatga actagttata gtcaatgaaa aaataacaag taaaaatgaa gtgtttaatt
     1681 attctttaac aagaattaat tacaaagaga ttaccaagtt ttcactagaa aaagttcctt
     1741 tttggggaga attttgttta aaaattaaat gtaactggaa aagaatgtat ttctatattg
     1801 atggtgatga tgctcttaca ttcggtaaaa ctactttttc tagttttaat tttcagtttc
     1861 tattaaaaaa taatttttat ggtttattga aataaggttg cgaaggaaga tgtagagtta
     1921 tttgcactgt tgtgttggta tatctcttaa tgctgtgtct ttttggggag a
//
LOCUS       DACBYO010000202         1883 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.211, whole genome shotgun sequence.
ACCESSION   DACBYO010000202 DACBYO010000000
VERSION     DACBYO010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.211"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..245)
                     /locus_tag="IVD26_002997"
     CDS             complement(<1..245)
                     /locus_tag="IVD26_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP6080887.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQ"
     gene            483..1652
                     /locus_tag="IVD26_002998"
     CDS             483..1652
                     /locus_tag="IVD26_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP6080888.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          669 a          315 c          295 g          604 t
ORIGIN      
        1 tcttgccata cctcctgaat ttgaccatca ggagtcgtaa tgaaaatagt atcattttca
       61 tctactaatt ctcttaagtt taaatattgt ttactagatg taaaattcga agctgctaat
      121 gacgagtctt cgcttttact ataaaatcct gttacttgta ttttatgttc ctggaaatac
      181 ttcccgaatg aacaacctac cttgccggct ccaataaaac caacgttcat aattatcacc
      241 tccataaaga agtgagacta caagtcccat tcttacgata tgagcttaaa aataaaaatt
      301 aaatcaaata tacagtatgt ttttttcaaa tatcatccat agttaattta tcataatatc
      361 ccatatttta aaataaaaga tagcgtaaaa tattttgtgt aaatagaaat ttagggtaga
      421 aaaaaaagtc cattctgtaa aattaaagtt accacacaga aattttatag gaggactttc
      481 tcatgactaa atttactata gaaattatgc aaacactact caataaaggg gatttagatg
      541 aattatttca ggatcattta gagcgagcga ttaattcact tctacaagca gagctaactg
      601 cttttttaga ttacgaaaaa tatgatcgaa atggattcaa ttcaggaaat tcccgtaacg
      661 ggaattattc acgtacattt aaaacagaat atggcgagtt gaatttaact attcctagag
      721 atcggaatgg cgaattttct caacaaacac taccagcata taagcgaacc aatgattcat
      781 tagaaacgac cattatccaa ttatttcaaa aaggcattac tatggctgaa atctccaaat
      841 taattgaaaa aatgtatggt caccactata cgccacaaac aatctccaac atgagtaaat
      901 tggtggctga agatgtttta gcttttaaag aaagaacgtt agaagccaat tattccgtta
      961 tatttatgga tgcgacgcat atccctgtga agcgacagac tgtttcgaag gaagcagtgt
     1021 atattacgat tggtattcgt ttggatggaa ccaaagaagt tcttgggttt actattgccc
     1081 caactgagtc tgcttatatt tggaaagaag ttcttcaaga tcttagaaaa cgtgggttag
     1141 aagaagtttt attagtagtg acagacggat taagctgtat tgaagaaagt atccatagtg
     1201 tgtatccgaa tgcccaattt caacaatgtt gtgtgcatgt atctagaaat atcgctcata
     1261 aagttcgtgt tcgaggtcga aaagaaattt gtgaggattt caaattggtt taccaagcga
     1321 attcaaaaga agaggcattg gatcacatcg actttatgac taggaaatgg aaaaagcagt
     1381 atccaagagt cgtcaattta ctcttgaatc ctgccctatt aaccttttat aatttccctc
     1441 acgccatcag acgaacaatt tattcgacga acctgattga aggctttaat aagcagctaa
     1501 aacgatatac tcgaagaaaa gaacaattcc ctaatgaaga atctctagag agattcttca
     1561 tttctcaatt taatcaatat aaccaaaaat ttttaggtag aattcacaag ggatttaaag
     1621 aaattcagga tacattagag tcgatgattt aactgtaatt aacagaatgg attttccatt
     1681 tacatataat tcttgacgct accataatct aaataaccat catattcatc tactacttat
     1741 ataattgagt tttattaaac tttttaagtt tctattctat caaatattta aacaatctct
     1801 gcatccgaaa agactacctc gtatagtttt actaacaata tttttattag cgtgttcaaa
     1861 tcctgatttc ttgtatcaat tat
//
LOCUS       DACBYO010000203         1874 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.212, whole genome shotgun sequence.
ACCESSION   DACBYO010000203 DACBYO010000000
VERSION     DACBYO010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.212"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..455
                     /locus_tag="IVD26_002999"
     CDS             <1..455
                     /locus_tag="IVD26_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080889.1"
                     /translation="GAELLRLETEKYIMNVYLERSELVENFVSYMICRKHYYSESEYY
                     SIFESMELMEELNSKDATVDDYYLVFTKFLTCGTESIVLMGMDYELAVPEVFLREYVE
                     EVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRKRMPYQRFERKKGQ"
     gene            836..1015
                     /locus_tag="IVD26_003000"
                     /pseudo
     CDS             836..1015
                     /locus_tag="IVD26_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1077..1261
                     /locus_tag="IVD26_003001"
                     /pseudo
     CDS             1077..1261
                     /locus_tag="IVD26_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, HicA family"
     gene            1295..1726
                     /locus_tag="IVD26_003002"
     CDS             1295..1726
                     /locus_tag="IVD26_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HicB family protein"
                     /protein_id="HAP6080890.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT          645 a          296 c          391 g          542 t
ORIGIN      
        1 aaggagcgga gcttctacga ctagaaacag aaaaatatat catgaatgtt tacctagaaa
       61 ggagtgaact ggtcgaaaac tttgtcagct acatgatttg caggaaacac tattactcag
      121 aatcagaata ttattcaatt tttgagagca tggaattaat ggaagagcta aacagcaaag
      181 atgcgacggt agacgattat taccttgtat ttactaaatt tttgacgtgt gggacggaat
      241 ctatcgtgtt aatgggaatg gattatgaac tcgctgtacc cgaagtattt ttgagggaat
      301 atgtagaaga agtagataac ccaggcgacg actggtacac gactttaact gattttttag
      361 atacctacac ttacgacgat acagaagaaa tccaaaatga acttgaccgt aaacgaatgc
      421 catatcaacg atttgaaagg aaaaaaggtc aataaccatt tataccgaaa agtgagaatg
      481 tgtgaaataa gaacaaaaaa ccttgaaatt aagggaatgg ttcttatttc gcaccaatcg
      541 ctccaaccgc ccccgccgct taggtggtgc gaaataagcg agcaaagccc gaaaacctaa
      601 gagaaagaag gagatttata tgaacaaaat tattccctta ttattagtcc tatttgttgg
      661 agaaatactt atgcgactta gtgcagctgt acatttaaac ctcgcagtat ttttggtaat
      721 actaatgttt tgtttgatct tttggcgatt tgtattagcc ctcgtaagtc tactattcaa
      781 gatgattgca gccatatttt tcataggatt atttcgatga aaggagagag taccaatgcc
      841 aattgcaata ggaaataaac ggttacccgt gacgttggat gaaaagagac aaaaagaatt
      901 gcagtaacca aagcagaagt acggcaaaag tgaatccagg attatgtgta ttgcgttaga
      961 tttattgatt gcgcaagaaa aagcaggatt tgacatacca gcactcaaaa agtgatcgca
     1021 ctttgcgcac gtgttaatac gtgttataat tattttgtaa ggaggtatag tgcacaatgc
     1081 cacttacggg aaaagaaatg cttaagttat tgaaaaaaat ggctgggttg agcgaaggca
     1141 agagggattt catcatcatc tttataagga tggtgttaga atcactgttc ctgttcatgc
     1201 caatcaagat cttggccgag gacttgagcg aaaaatttta aaggatgcgg gattgaaata
     1261 atctcgcatt cgattaaaga aaggattgac tgaaatgtta agtgagcctt tagcaaaaac
     1321 ctatcctgct atttttagcc cagaagaagg tggtgggtac tttattgaat ttcctgatgt
     1381 tcaaggtgct tacacaggaa ttaacgaaga cgatatatct tatggaattg ctatggcaca
     1441 agaggtgtta ggtatggttt tagcagatta tattgagcat gaagatctac ttccagaacc
     1501 aacaccaatc aataagattt ctgttgaaga tgattctttt actactttaa ttcgtgtaga
     1561 tgttgccaaa tatttgaaag acacagaact tgtcaaaaaa accttaacaa ttcctcaatg
     1621 ggcggataag ctaggcaaaa gggctggcat aaatttttca gtccttctaa cagaatcaat
     1681 tgcagataaa gcagataaca ttcttcgttc tggaagaaat aattagaact caaaagggtc
     1741 agaaacttaa aaatctttgg cttctttttt tactacaaag atggcttctt taaattattt
     1801 gcctgattga tttaaaaaaa ttgcgcaaag actacgagct aattaagttg ctcgtggtct
     1861 ttttttatga aaac
//
LOCUS       DACBYO010000204         1741 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.213, whole genome shotgun sequence.
ACCESSION   DACBYO010000204 DACBYO010000000
VERSION     DACBYO010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.213"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            292..1332
                     /locus_tag="IVD26_003003"
     CDS             292..1332
                     /locus_tag="IVD26_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAP6080891.1"
                     /translation="MRRKEVKVISFGELLLRLAAPGYSKLFQRDSLETTFCGGEANVA
                     VSLAIFGYQSEFITKLPDSDVGYAAANALRYFGVNVDNIIFGEGRMGLYYLEKGAAQR
                     PSKVIYDRKFSAISLADSDEFKWKEILNDANWFHWTGINPALSENLFETSLDACQAAK
                     KRGITISCDLNYRSKLWTSEEAKEKMEQILPLVDICICNEEDAEKVLGIKAEHTNINS
                     GELNKDGYVQVAREIHKKFGCRYVATTLRRSYSASRNGWSAMLYEAEKDKAYFSTEYN
                     IQIVDRVGGGDSFSAGIIYALCENMSGQKAIEFATASSCLKHTIEGDFNRTTIEDVYN
                     LMNSGGNGRVLR"
     gene            1581..>1741
                     /locus_tag="IVD26_003004"
     CDS             1581..>1741
                     /locus_tag="IVD26_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6080892.1"
                     /translation="MTYTYLTTDELVIIESYLKINQSVAKTAHCLNRSSQTIHKVYLF
                     FKQRKSALE"
BASE COUNT          616 a          211 c          374 g          540 t
ORIGIN      
        1 aacttgcgag aaccagttta ggggtatata ttttacatga aaatcattat ttcattgatg
       61 gtatgaagtc tagaggctta atatgggatg ggatatttgg attaggcaaa aggtttttag
      121 atagggattt ttggatttgg tttataattg cagttgtagt tgtgtgcata atttgcatgg
      181 ctatcgatgt tgtaagagaa aaatttgaaa gacagatttt taaaattaag agtgtaaaga
      241 acctgtgtaa acttatgaat catgttataa atatataccc ataattaata aatgaggaga
      301 aaagaagtga aagttatatc attcggagaa ttattattga gacttgcagc acccggttat
      361 tcaaagttat ttcaaagaga tagtttggag actacattct gcggagggga agctaatgta
      421 gcggtatcct tagcaatatt tggatatcaa tcagaattta taacaaagct tccggattca
      481 gatgttggat atgcggcagc taatgctttg cgttattttg gagtaaatgt tgataatatt
      541 atatttggag agggacgcat gggactgtat tatttagaaa aaggagcagc tcagagacca
      601 tctaaagtaa tttatgacag aaaattttct gcaatttcgt tagctgatag tgatgaattt
      661 aagtggaagg agatcctaaa cgatgcaaat tggtttcatt ggacagggat aaatccagca
      721 ttgtctgaga atctctttga gacgtcctta gatgcatgtc aggctgccaa aaaaagaggt
      781 ataacaattt cttgtgattt aaattatcga tccaagcttt ggacatcaga ggaagcaaaa
      841 gaaaagatgg aacagatact accattggtt gatatttgta tttgtaatga agaagatgca
      901 gaaaaagtgc taggaattaa agctgagcat acaaatatta atagtggaga attaaataaa
      961 gatggctatg tgcaggtggc tagggagatt cacaagaagt ttggatgtag gtatgtagct
     1021 acaactctgc gtagaagtta ttcggcaagt agaaatggtt ggagtgcaat gttatacgaa
     1081 gcagaaaaag ataaagcgta tttttccaca gaatacaaca tacaaattgt tgatcgcgtt
     1141 ggtggtggag acagcttttc tgctggtata atatatgcgt tatgtgaaaa tatgtccgga
     1201 caaaaggcta ttgaatttgc gactgcatct agttgtttaa aacatactat agaaggtgat
     1261 tttaatcgaa ctacaattga ggatgtatat aatttaatga atagcggtgg aaatggtcgc
     1321 gtgttgcgtt agtcaacata taaagataaa tcacagtaat ttttatggtg attatctgtc
     1381 ttagtagtga ttagaataac gtgaaaataa attgttgagc gtttatactg ttttgaaaaa
     1441 taaatttaac atattgaaaa atacaaatat atacgtatat tataaagcgc cgattgtaaa
     1501 attaagctag acaactaaaa cagtcatttg tgctacactc aaaatagttc cgaccaaaga
     1561 attataagga gtgagtgcaa ataacctata cctatcttac aacggatgaa cttgtaataa
     1621 tagagtctta tttgaaaatt aaccaatctg ttgctaaaac tgcgcattgc ttgaatcgtt
     1681 caagtcaaac gatccataaa gtatatctgt tcttcaagca aagaaaatca gccttagaat
     1741 a
//
LOCUS       DACBYO010000205         1727 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.214, whole genome shotgun sequence.
ACCESSION   DACBYO010000205 DACBYO010000000
VERSION     DACBYO010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.214"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            165..587
                     /locus_tag="IVD26_003005"
     CDS             165..587
                     /locus_tag="IVD26_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080893.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            597..800
                     /locus_tag="IVD26_003006"
     CDS             597..800
                     /locus_tag="IVD26_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080894.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            1011..1595
                     /locus_tag="IVD26_003007"
     CDS             1011..1595
                     /locus_tag="IVD26_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6080895.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          614 a          235 c          308 g          570 t
ORIGIN      
        1 tttttaaatg gcaatatttt ttgtaaataa atgtcaatca agaaaattta aacgattatg
       61 acattaaaaa tatattttat gaattttcta gtatataact tgatttatct gttaagattt
      121 attaagaaaa cgttttctta tttttgattt cgaggtgata gacaatgaaa aataagttta
      181 ttttatcttt aggtatttta actattggaa ttagtgtaac tggaactaca attcctacat
      241 ttgctgatag tacaaatgaa ccaactactg tagtagataa taaccaagaa ttaactcctt
      301 tagataggaa cggaatagcc attggtaacc caactaacga cttaactgtt actgaaaatt
      361 atttaatagt ttctccatta cttgctcgag cagcttctaa aacgatacga gtgacaggaa
      421 cgatgatttt tgataaagtt ggttggcctt ctagacctcc tcaatcacgg aattggaaag
      481 aaaaaagaaa tggttattgg tactatggaa aattgtattt acaaagttat aaatcagctg
      541 gaaacaattg gattgcgact tattcaggaa ccttaactag aaagtaggga ttttttatgc
      601 cagaatttgt gaacacacca aatttttatc aagatagcga tattctaagt aaaattaatt
      661 taccgaaaga agaatcagct ttacaagttc agcgaacttt acaggagaca caaaaaattc
      721 aaaaatcaat ttctaatcta gaagattctg aagaaaaaag aaaaaaaaga gaccaaaaaa
      781 catatcaaaa agaaaaataa tgattttaaa aaaagagtgt ctagtcgaca ttcttttttt
      841 ctaattgaaa gtgttcataa aatcacccat ttctggacac tttctttttt tgctttattt
      901 ttcaaaaaaa caattcattt catgttcata aacccataac aatatctatg ttcagttaaa
      961 ctatatggat aaagttatgt tacaataaaa ttaatgaagg agtgattttt ttgaaaatag
     1021 gatacgcccg ggtatctact ggtttacaaa atttggattt acaagaagac agcctaaata
     1081 aatttggttg tgaaaaaatt tttactgatc atatgagtgg ggcaaaaagt aatcgaccag
     1141 gattagaaat ggccattgat tttgttcgct ctggcgatac acttgtcgtt tggcgcttag
     1201 atcgtttagg tagaaatatg gaagatttga tttcaatcgt caatcgactg aatgagcgtg
     1261 gtgtgagttt tcatagtatt caagaaaata ttacgatgga caaatcaagt tctacaggac
     1321 agctcatgtt tcatttgttt gcggcatttg cagaatttga gcgtaatttg atcctggaac
     1381 gatccgcagc aggacgagca gctgctcgtg caagaggacg gtttggtggt cgtcctgaaa
     1441 aattgtctga acaagatttg gaattactga agactttagt ggatagcggt acacctatta
     1501 agactattgc ggaacggtgg aacgtctcaa gaaccaccat ttatcgttat ttggcaaaaa
     1561 tggaggagaa aaatggaaag acaaattctc attagttttt gtcatttaat gctgaaaatt
     1621 tttgccattt atctagaaaa gtgacaatag tatgagaatt ttttgtaagt gtctactgat
     1681 aacttattct caaatgttgt aaggatttta ttcatttgtt aatatta
//
LOCUS       DACBYO010000206         1715 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.215, whole genome shotgun sequence.
ACCESSION   DACBYO010000206 DACBYO010000000
VERSION     DACBYO010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1715
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.215"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(138..428)
                     /locus_tag="IVD26_003008"
     CDS             complement(138..428)
                     /locus_tag="IVD26_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080896.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(546..806)
                     /locus_tag="IVD26_003009"
     CDS             complement(546..806)
                     /locus_tag="IVD26_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080897.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(943..1356)
                     /locus_tag="IVD26_003010"
     CDS             complement(943..1356)
                     /locus_tag="IVD26_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAP6080898.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
BASE COUNT          652 a          270 c          256 g          537 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggtt
//
LOCUS       DACBYO010000207         1667 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.216, whole genome shotgun sequence.
ACCESSION   DACBYO010000207 DACBYO010000000
VERSION     DACBYO010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.216"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..127)
                     /locus_tag="IVD26_003011"
     CDS             complement(<1..127)
                     /locus_tag="IVD26_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP6080899.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRK"
     gene            complement(124..777)
                     /locus_tag="IVD26_003012"
     CDS             complement(124..777)
                     /locus_tag="IVD26_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP6080900.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            1065..>1667
                     /locus_tag="IVD26_003013"
     CDS             1065..>1667
                     /locus_tag="IVD26_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6080901.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQ"
BASE COUNT          537 a          302 c          231 g          597 t
ORIGIN      
        1 cttttctcgt ctccaaatat gttttaggaa agataaaaaa aattaatgaa tgaactaata
       61 taattattat tccaagaaca gaaaatattt gtatgaacat ttttggaaat atctttaatt
      121 ttttcatttt ctctccaatt tatatcctac atttcttata gtagttatac agtctaattg
      181 taattttttt ctaagttctt ttatatatac atctattact cgatcataag gagtttcttc
      241 gctatctttc catacataat caataatttg cattcttgtt aacacttgtc cattattatc
      301 caataaacat tttaatactt ctagttcttt tgcatttaca tctatttctt caccatttat
      361 tttagctgta tagctattaa aattaaccga tagatcctta tattcaaact tctctaaatg
      421 tccataattc ttcttaatta aagaatctat tctagctttt aagaccggca atgaaaatgg
      481 cttttctaca tatccgtcta ctaaattagt aaatgcatca attttatatt cttcatcact
      541 aaatgcagtc aagattagaa ttggtaaatt gcttttcttt ctaatttctt tcaacacttc
      601 taaaccattt ataaaaggta tctgaatgtc taagataacc aaatttatat cgctattaaa
      661 ttttgacaag gcttctcttc catctttagc ttgaataaca gtatatccaa attctgaaag
      721 atattcactt attccctctc ttatcatatt atcatcttca acagttaata ttttcatata
      781 tacctccact taagcctata cactagatat tatacagcat attatggctc tataatatct
      841 agtgttggtg acaccttctg ttgccaatac tttttctttt ttctaataaa tgcaaacaga
      901 caccttgaaa tcctttagaa taaagggttc tataatattt tgtgttgttg gaaaatcgaa
      961 ggcgattttc tactaacact ttttcttcgt ttcaactcaa aaagagactc acttttggta
     1021 aaatttagtc gaccaaaaca tcaccctacc aaaggagtcg ctctatggat aatcatacta
     1081 gaaaattact cggattaaca gataaacatt tattttttga tgaagaatgg ctgattgaaa
     1141 aagaatataa aggcgttcaa gcgcagttta ttaaagggag attggatgac tcaccttccc
     1201 attgtgaaca ctgtggatcg attcgtatta tccgcaacgg ttcctatacg acacgtactc
     1261 agatattgaa agtcaaagaa aagttgacta ttttagaatt aaaacgtacc cgttttctat
     1321 gctatgattg tgggcagacc ttttctgcga aaacggactt agttgatgaa catcatcaac
     1381 taacaaagga actgaagcag gcgattctca tagaactgta cgaaaatcaa tcacgtaaac
     1441 taatcgctaa gaagtacttc gtctcggatg ggacggtgac acggatcttg cgtgaagcaa
     1501 cgaagcatta ccagccacgt atgaacttcc ttccgacggt gttgtgtatg gatgagttca
     1561 aatcaatgaa gtctgtttct ggttccatga gttttatttg tgttgatggg acaacccatc
     1621 agctatttac gatccttgaa gatcgcagac tttacaaact aactcaa
//
LOCUS       DACBYO010000208         1640 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.217, whole genome shotgun sequence.
ACCESSION   DACBYO010000208 DACBYO010000000
VERSION     DACBYO010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.217"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            416..>1640
                     /gene="ltrA"
                     /locus_tag="IVD26_003014"
     CDS             416..>1640
                     /gene="ltrA"
                     /locus_tag="IVD26_003014"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP6080902.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRL"
BASE COUNT          586 a          299 c          388 g          367 t
ORIGIN      
        1 aacttggtgg tgaaagtcca ctacaggctt ggcagtagga actgttagcg aaagacaagg
       61 cggcaatcgt gaggttgtgg ctgaaggaag tcggacgcaa actcctgaac tgacgaacag
      121 aaactagata caaggctgaa ttaggtcgga taagtcttca tcacaagaca aagtccaata
      181 ctgcccgaaa cctatacagt aaatctagca gttacatggg aggaaagttt tcactcttac
      241 cgggggagat ctcatgaggg tgttgtgggc gttgaatgaa aacaaaccag cacaacgatc
      301 atggcgacat gatggtgaat catgagaagt cagccgaggt catagtagta acgacactga
      361 ccgttacgaa ggactgaaca ataagaatct tgaataattt aggaggtgtg agaagatgcg
      421 acgaccgcag aaaacaagaa aacttggcta tcatcaaaga gctagtgtgg aacacgaagg
      481 gtatgatgaa gtgcgcagca cttcttgcgg tgaacagagg aaacaagatg gtgtagaaaa
      541 tctgtttggg agaattctag atcggaataa tctcaatcaa gcgtatcttc aagtagtcag
      601 aaataaaggg gcggctggtg cagatgggat gaccgtcgat caactgcttc cttacttgaa
      661 agagcaccgc gaggaattac tatccaattt acgccaaggg aactataaac ctcagcctgt
      721 tttgcgagta gaaataccga aaccaaacgg cggtgtaaga aaactaggaa ttcccacggt
      781 tattgatcgt atgcttcaac aggcaatcaa tcaagtgtta caaccgctat ttgaaccaga
      841 attctcagat aatagttatg ggtttcgccc aaatcgcagc gcacatgacg cagtgaagaa
      901 agcaaaatct tattatgaac aaggttaccg atatgtggtg gacattgata tgaaagccta
      961 ctttgacacc gtaaatcacg ataagctgat gtatttcatt gagcggaaag taaaggacaa
     1021 acaagtccta aaactgatcc gtcaatactt aatgagtggt gtaatggaaa atggactcat
     1081 cacaacaact gaagaaggaa cgccccaagg aggcaatctc tctcccctgt taagtaacat
     1141 ctacctgaac gaatttgatc aagtgctaga aaatctagga cataaatttg ttcgatacgc
     1201 cgatgactgc aatatctatg ttagaagcaa acgagcagga cagcgtgtga tgaagaaatc
     1261 cattcaattt ctcgaagaac aactaaagtt gacggtaaat cgagaaaaga gtgcggtagg
     1321 aagtccattg aaacgaaagt ttcttggatt ctgcattctg ccaacaaaga aaggtattaa
     1381 aattcgccct cacgcaaaag caaaacagcg tgtgaaaagc aagctcaaac aactcactaa
     1441 aagaaaccgt ggaagaagta tccaacttat tttaaaagaa atcaagcaac taatgactgg
     1501 ttggatcaac tactatggaa ttggtgagat gaaagaattc atgagggagt taaacggttg
     1561 gttgaagcga agaatcagac aatatatttg gaaacaatgg aagaatccaa gaaccaaaag
     1621 aaaaaatctg attcgtttag
//
LOCUS       DACBYO010000209         1611 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.218, whole genome shotgun sequence.
ACCESSION   DACBYO010000209 DACBYO010000000
VERSION     DACBYO010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1611
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.218"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            99..1565
                     /locus_tag="IVD26_003015"
     CDS             99..1565
                     /locus_tag="IVD26_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAP6080903.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          450 a          292 c          335 g          534 t
ORIGIN      
        1 gaaaattagt ttatatttct taaataagtt ttttagttaa atttttcggt aaagatgtat
       61 aatattttct gaaaatttaa agaattgggg tatagattat ggaaaaacag caagacaagg
      121 gcttcttcgg gcagccgaag ggattgtcaa ctttgttctt cactgagatg tgggaacgat
      181 ttagttatta cggtatgcgt gcattactta tctattatat gtacgataca gttgccaacg
      241 ggggacttgg attaccacga gcaacagcat tagctatcat gtcgatctac ggatctttga
      301 tctacatgtc tagtatcgtc ggcggatggg tatctgaccg agtgttagga gcaaaacgca
      361 ctgtattctt cggtggagtt ttcattatgc ttggccacat cgtcttggct ttaccatttg
      421 gtgtaagtac attgtttgtt tcgatggcat tgattattat cggaaccgcc tttttgaaac
      481 caaatgtttc tggcatggtc ggacatcttt attcaaagac tgacttgcga agagatgcag
      541 gattttcgat tttttacatg ggtgtcaact taggggcatt attagcacca ctaatcgttg
      601 gtacaatcgg tcaagaatat aactatcatt tagggttctc tttagctgct attgggatgt
      661 tctttggatt attacaatac atcatccaag gacgcaagac attagacgga gtgggtacaa
      721 caccgccgaa tcctttgaca actgaagaac gtaaaggatt catccgtaac ttgatcatcg
      781 cacttgttgt tatcgctgca gtattcggcg gggcacaact aactggtcat ctgacaattg
      841 acttttttgt caatacaatc agtgtattgg ggattatctt accgttgtat tactttatca
      901 aaatgctgac ttcaaaagat gtaactgctg aagaaaaacc aagagtatgg gcttatatcc
      961 cattattcct tgcagcaatc attttctggt cattacaaga acaaggttca tctatcttag
     1021 ctttatttgc tagtgaacgt acacaatcta cgctatttgg tgtaacgatc caagcaagct
     1081 ggtatcaatc attgaatcca attttcatct ttattctgac accagtattc gtaacgatgt
     1141 ggacgaaact tggtgaacgt caaccatcta cagtagtgaa attctctctt ggacttttat
     1201 ttgcaggatt atcgtacttg ctattgatgt tgccgggtat gctttatggt acaagtggaa
     1261 aagtaagtcc attgtggttg ttgggaagtt tcttcatcgt ggttattgct gaattgtgtc
     1321 tttcaccagt tggtttgtct gtgacaacaa aattagcacc acgagcattt gaatcacaaa
     1381 caatcgctat ttggttctta gctgatgctt cttcacaagc aatcaatgca caaattgcac
     1441 gcttctacac accgggaaca gaatctgctt acttcggtat tatcggtgca gtagcaatcg
     1501 tcggtggtat cttgctattt actgtgaaag aaccaatcaa aaaactaatg ggctctattc
     1561 attaatcaat gaacataaaa acaggaattg cttatttgca gcagttcctg t
//
LOCUS       DACBYO010000210         1604 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.219, whole genome shotgun sequence.
ACCESSION   DACBYO010000210 DACBYO010000000
VERSION     DACBYO010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.219"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            635..>1604
                     /locus_tag="IVD26_003016"
     CDS             635..>1604
                     /locus_tag="IVD26_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAP6080904.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVDDK
                     VHPLKLSWSIDRITIVGKLNDTIAYWTQNGVVFVDFEQLMRLNENQGYLKSVGTNGWQ
                     LFDQYGEDIAYIEMLKFHPDKGRIDFNPNKIGEFLKGSMKQFIHDLFLDAHFSRADIA
                     CDILGVPDDFITQYRIVDPVSFKPIYGRSGKLETAYWGSRASERQVRMYNKKLEQERK
                     KQIVPKEIETWWRIEMQLRRGKATDWHAMVRESLDSFASPHYLPGDVKPVDRIMIKGL
                     NQDHSEWAYISRNLKYRLRKLLKEESQNDELTNHLRETFKESANDLK"
BASE COUNT          540 a          251 c          364 g          449 t
ORIGIN      
        1 aatacaagca tttctcataa taatcgtgag ttaactgata gccaaaaaat caatggtttg
       61 tctggtagaa aataattagc agatttacaa gtgggaaata aaaagctgaa agaagaaaat
      121 tgcatttcaa actacatttt ctacaatagc tctaaaatgg catattttgc gttctgagcg
      181 gttttagcgt ttatttcgtt tagttatcgg cacaatcgtt aaaacacgtt agaggagcga
      241 aaatggagcc tgtaaggcga ctggtagcgg aacgatcgtg ttagattgtg aaaaccgata
      301 gctgaatgaa ataaacagcg ggtgcgccct ttccatttcg gcaggaggag gctcaagggg
      361 ttcggggaat gaaattccct gaggtctttt tattttttta ggaggagtgc tataatcaaa
      421 gaaaacgaga aaaaagagca aaataaaagc cgagcagtgc gctaacactc tcgactattt
      481 acggaaacta cttcacctag ctccgtaact caggttcatt atacgaatat ttttaggttt
      541 cttcaagcta gagatttttg gatatgaatt tttagggtta cgtgaactct ggaaattctt
      601 tccaaaagtc tcttttttcg tctggaggac gaaaatggca aatgaaaatc agttgagtga
      661 aattcaatca aaaattgaag gtcgaggggc agaaaaaaga acaacgataa atcagctcga
      721 aaaacttaac cgtatttcta acaggcggtt aagtgttgac gataaggtac accccctaaa
      781 attaagttgg tcaatcgatc gaattacaat cgtcggaaaa ctgaatgata ccatagctta
      841 ttggacgcaa aatggagttg tgtttgtcga ttttgagcaa ttaatgcgtt tgaatgaaaa
      901 tcaagggtat ttgaagtcgg ttggtacaaa tggttggcaa ttatttgacc aatatggaga
      961 agatatcgcc tatatcgaaa tgttaaaatt tcaccctgac aaaggtcgta ttgattttaa
     1021 tccaaataaa attggcgagt ttttaaaggg gtcgatgaaa caattcattc atgatttgtt
     1081 tctggatgcg catttctcac gtgcagatat tgcttgcgat attctcggtg ttcctgatga
     1141 ttttattacc cagtatcgaa tcgttgaccc tgtgtctttt aagccaattt atggccgttc
     1201 tggcaaatta gaaacagcgt actggggtag tcgtgccagc gagcgacaag tgcggatgta
     1261 caacaaaaag cttgaacagg aacgaaaaaa acagattgta ccaaaagaaa tcgaaacatg
     1321 gtggcgtata gaaatgcagc taagacgtgg caaagcaaca gattggcatg cgatggttcg
     1381 ggaaagttta gatagctttg caagtcctca ttacttgcct ggagatgtaa aacctgttga
     1441 tagaattatg ataaaagggc tgaatcaaga tcattcagag tgggcgtata ttagcagaaa
     1501 tttgaaatat agattgcgca aattgttgaa agaagaaagc caaaacgatg agttgacgaa
     1561 tcatttacga gagacgttta aggaatctgc aaacgacttg aaaa
//
LOCUS       DACBYO010000211         1585 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.220, whole genome shotgun sequence.
ACCESSION   DACBYO010000211 DACBYO010000000
VERSION     DACBYO010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.220"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(94..528)
                     /locus_tag="IVD26_003017"
     CDS             complement(94..528)
                     /locus_tag="IVD26_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP6080905.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(628..1476)
                     /locus_tag="IVD26_003018"
     CDS             complement(628..1476)
                     /locus_tag="IVD26_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP6080906.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
BASE COUNT          559 a          310 c          238 g          478 t
ORIGIN      
        1 aaataagaga aagcacatga aacagacgcg ctttctcgaa tagcaaacat atacaaaaaa
       61 tatcagagac aaaaaataat ctcatcataa acattacata tatttctcaa aaagttgttt
      121 tctttcttca aaaattactt cacgatggac ctgatgaagc atccataaat aaccaaaagg
      181 atctctgaac attgagttag tcacaccaaa gtccatcatt tctgtcattt cttgaatctc
      241 tacacagcca tttcgtaatg ctttattatg tgtgtcctcg atatcagaga cgatgatatt
      301 gaaccagatc gtatttggat gttcagcagt aggagcagtc aaaccaagag acgtgttttc
      361 atccagcata tggaatctcg taccatacaa ggtaaaaatg acttcattat tgcctctagg
      421 gtaatctgtt gcctcaatca gttgtatttc atcaaagatt gtttgataca gttctagtgc
      481 tttcaaacta tcatttaata caaaatcgat ttccgttcct ttatgcataa agatctcctc
      541 tccttttcag tcgaacagtt actagattct tttattatac cagctaaaga aaacgcattc
      601 aaaaaaatag cggatttact taccaactca ttcgattgga tgataagtaa atccgcgtcc
      661 cattacttct gctacgctgc tgacaatgac aaaggcactt ggatcgattt cttctatcaa
      721 tggtttcatt cgggaaaatt catgatcagt cacaacgatc aataaaacct cttttgactt
      781 tcgattatac ccgccttttg cctctagcag ggtaaggcca cgtccaatct cagcacttaa
      841 gcgaaggcgg atgtcttcca aataatgttc actcatgacc ataacagatt tctttcgatt
      901 gatacctgtt tcgatataag tcatgacaat tgaagtgatt gcaatagata aaatagcata
      961 aagaaactct tctattccaa aaataaacag attaagagaa acaacgaatg cgtctgtaaa
     1021 aaataagcca atcgaagtat tcaagtggaa atatttttta aaaatgaggg gagggatcgt
     1081 cgtaccgccg ctagaagagt tgtttttata taaaatcgca actcctaaag caaaaatcgc
     1141 acttccaaaa atgacagaca acaaccgatc tgaagtaatc attgtttctg gaactattgc
     1201 aatgattaaa ggaaaaacca agcttccgaa aagtacttta aaaaagggtt ttttacctaa
     1261 aaatagaaga gctagtacca acataacgat attcaacact aaaataacta tagctcggtc
     1321 aaagcctaaa gcagcttcca gtaatattcc tagaccgctg acacctccag cagcaatatg
     1381 atgaggccct aaaaacatat tgatagcgac tcctaatatg aagagggcaa aaataatctt
     1441 aatgtatgtc catataaatt gtctcgtttc tttcatttat tcacttcctt aattcattaa
     1501 taatactctt atcttattat aacttacttt tcaccttaag ttaactttaa ttaataaaaa
     1561 aattaggcta gtctaaatta ttatg
//
LOCUS       DACBYO010000212         1583 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.221, whole genome shotgun sequence.
ACCESSION   DACBYO010000212 DACBYO010000000
VERSION     DACBYO010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.221"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            40..1533
                     /gene="guaA"
                     /locus_tag="IVD26_003019"
     CDS             40..1533
                     /gene="guaA"
                     /locus_tag="IVD26_003019"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAP6080907.1"
                     /translation="MITRRIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYD
                     EKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALF
                     QNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSE
                     YGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVL
                     LQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDP
                     EEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVG
                     GLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEK
                     LEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSI
                     DGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE"
BASE COUNT          482 a          325 c          356 g          420 t
ORIGIN      
        1 aaaattatcg tacttgatta cggtagtcag tataaccaac tgatcactcg ccgtattcgt
       61 gagttcggtg ttttctcaga gttgatgagc caccgcatta ccgcagaaga agtaaaggca
      121 atgaacccta aaggaatcat cctttctggc ggaccaaaca gtgtttatga tgagaaggcc
      181 tttggtattg atgaaaagat ttttgatttg gggatcccag ttttaggaat ctgttacggt
      241 atgcagttga ttacttataa attaggcgga aaagttaaac cagccaaaaa ccgtgaatac
      301 ggaaaagcag aattggaaat cacttctgca gaagcggccc ttttccaaaa cactcctgaa
      361 aaacaaaccg tttggatgag tcatggtgac ctagttaccc aagcaccgac tgatttcgat
      421 gtcgttgcta ccagcaaaga ttgccccatc gcatcgatcc aaaatgcaga acgcaaaatg
      481 tacggaatcc aattccatgc agaagttcgc cattccgaat atggaaatga cttgttgcgc
      541 cattttacac tagatgtctg ccaatgtact ggtgactgga caatggataa cttcatcgac
      601 atggagatcg caaaaattcg tgaacaagtc ggtgacaaaa aagttttatt aggcctttca
      661 ggcggagtag attcctctgt tgttggtgtt cttttacaaa aagcgatcgg cgatcaatta
      721 acatgtatct tcgttgatca cgtattgttg cgtaaaggtg aagcagaaca agttatggaa
      781 agtcttggcg gaaaatttgg cttgaacatt ataaaagtcg atgccaaaga acgtttctta
      841 tcaaaacttg ctggcgtgtc tgatccagaa gaaaaacgta aaatcattgg aaatgaattt
      901 gtatatgtct tcgatgatga agcaaccaaa cttgccggtg aagaaggcgt ttctttcctt
      961 gcacaaggaa ccctttatac cgatgtgatc gaatcaggaa ctgaaactgc ccaaaccatc
     1021 aaatcacatc acaatgtagg tggattacct gaagacatgc aattcaagct gatcgagcca
     1081 ttgaacacat tgttcaaaga cgaagtacgt gaattaggta cccaattagg catgcctgac
     1141 agcatcgttt ggcgccaacc attccctgga ccaggcttag gtattcgtgt ccttggtgaa
     1201 ttgacagaag aaaaattaga aatcgtccgt gaatcagacg ctatcttgcg cgaagaaatc
     1261 gccaatgccg gtttagatcg cgacatctgg caatacttca ccgtcctacc aggcattcgc
     1321 tctgttgggg ttatgggaga tggccgtacg tatgactaca ctgtaggtat ccgtgctgtc
     1381 acttctattg acggcatgac cgctgacttt gcccgtatcc cttgggaagt cttgcaaaaa
     1441 atcagtgtcc gtatcgtaaa tgaagtcgca cacgttaacc gtatcgtgta tgatattacc
     1501 agcaaaccac ctgcaacagt ggagtgggaa taagacgtaa atataatatg gatggggaat
     1561 gccgataaat caacgttttt caa
//
LOCUS       DACBYO010000213         1578 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.222, whole genome shotgun sequence.
ACCESSION   DACBYO010000213 DACBYO010000000
VERSION     DACBYO010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.222"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(606..962)
                     /locus_tag="IVD26_003020"
     CDS             complement(606..962)
                     /locus_tag="IVD26_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAP6080908.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(976..1386)
                     /locus_tag="IVD26_003021"
     CDS             complement(976..1386)
                     /locus_tag="IVD26_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP6080909.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
BASE COUNT          490 a          281 c          224 g          583 t
ORIGIN      
        1 tgtttgttgt cttgaattga atcaagacgc cctacacatt tggtttgtct tactttgttc
       61 agttttcaaa ggtctacttc atcaggagtg ttccccgatt cgtttttggc tgccgtagca
      121 acttttatat catatcagag agacaagtaa ttgtcaactc ttttttaaaa gtttttttga
      181 tttcgttttt cgaaatctta cagcaactca tttatcataa cttatcattt gttatttgtc
      241 aagaactttt ttgaagtttt tttcgataga atcaagcttc acaagtggtt cttttttaac
      301 aactcagtta tcttatcatg tcatttctaa catgtcaaca actattttat atgtttttta
      361 aaatactatt ttattgcttt gctacttaaa acaacagaaa tgaatatatc atgtaaattt
      421 acacatgtca atatattttt aactctatat ccccacctag atttgaattt tgaccacata
      481 aattgagcat gtctctatag tagaaaaata aagtcaaaaa aagaacacat aacacgcttg
      541 atgctaagtg ttcgactgtt acaactgtat gaaatgctca gtgacttgat taaaacagtt
      601 aaagtctatt tatttaagat aagctgttcc atcaactgct cattgtatcc aataaataga
      661 acttcatcga taataatcaa aggacgtctg aggagattgg tatgttgtgt gcataaaaaa
      721 atcagttgtt tttttcctac acaggaaagg tcaatcgcaa tgttgtgaaa agcctcagac
      781 caagtcgcaa atagctgttc tgcttgcact tcttcaaaac tgcataattc ttctgcttct
      841 tctgtactta aatcgcgttc ttctaagtca acaaattgat aaggcaattg atggtgttct
      901 aaccattgtt tcgccttcag acttgttaca cagtgcgctg atccatagac tttcacttcc
      961 acgaaggctc cctccctatg aatttaagat gttattgttt tgtaaataga tcagatttct
     1021 ggcaacacat cgaatttcac gagggacaaa tgaccggatc tcatcttcat taaatccgat
     1081 tagtattctt ttttcatcaa tcaaaatagg tcgtctcaat aatgaaggat attctttgaa
     1141 taagacgatc atttgcttta aagttaattc gttaaaatct atgcccagct tttcgtaaat
     1201 tttcgaccga gtggaaataa tatcttgaac tcctccttca gtcgctgcca agatcttttt
     1261 gatctcactt tctgttaacg gttcggcaaa aatattcttc tcttcaaatt caagttgatt
     1321 cgcttgcaac catgctcttg cttttctaca ggaagtacag ctaggcgaag tatatacttt
     1381 tatcattttc tcactccttt ttaattataa tccaattcta cagtaatttc ttttaaaata
     1441 ccaattatta gctaataaaa tataaaaaaa atcaaaataa ctgattattt acgtttgaat
     1501 aatgagaatt tttctatata ttctctattt tgataatagt attctcattt tcaaaataaa
     1561 taagggaggt gtgacaaa
//
LOCUS       DACBYO010000214         1553 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.223, whole genome shotgun sequence.
ACCESSION   DACBYO010000214 DACBYO010000000
VERSION     DACBYO010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1553
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.223"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            635..>1553
                     /locus_tag="IVD26_003022"
     CDS             635..>1553
                     /locus_tag="IVD26_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAP6080910.1"
                     /translation="MSKKGIIVNEWEKLNRISNRRLNVQNLNTPLKLQWSIDRITIVG
                     KLKENIYYHTPNDVLILNFEQLMQLNEGNGFVKSVGKNGWQIVDQYEENIAYIELLQF
                     HEGKARIDFNPNKIGQFLASSMKNFIHDLFLEPHFSRADIACDMVNVPDEFIMQYRVV
                     DPVSFKPIYGRSGKLESAYWGSRASERQIRLYNKKLEQETKRKVVPKEVETWWRLEMQ
                     LRRGKATDWHNMVQESLNSFASLHFLPIDTTPTDRIMLAGLMSDQNFWSLLSRNSKYK
                     YRELLKEESQNDELTNHLRETFAESADNLK"
BASE COUNT          511 a          240 c          342 g          460 t
ORIGIN      
        1 aatacaagca tttctcataa taatcgtgag ttaactgata gccaaaaaat taatagtttg
       61 tctggtagaa aataattagc agatttacaa gtgggaaata aaaagctgaa agaagaaaat
      121 tgcatttcaa actacatttt ctacaataac tctaaaatgg catattttgc gttctgagcg
      181 gttttagcgt ttatttcgtt tagttatcgg cacaatcggt gaaacacgtt agaggagcga
      241 aaatggagcc tgtaaggcga ctggtagcgg aacggtcgtg ttagattgtg tagccgatag
      301 ctgaacgaaa taaatgctgg cagcgccatt ctatttcggc aggaggaggc tcaaggggtt
      361 cggggaatga aattccctga ggtcttttta ttttttctag aggagtgcta taatcaaaga
      421 aaatgagaaa aaagagtaaa aaaatagtcg agcagtgttg acgcactctc gacctttacg
      481 gaaactactt cacctagttc cgtaactcaa gttcattata cgaatatttt taggtttctt
      541 caagctagag atttttggat gtggattttt agagttacgt gaactctgga aattctttcc
      601 aagaatctct tttttcgttg aggaggagct atttttgagt aaaaaaggca taatcgtaaa
      661 tgagtgggaa aaacttaacc gtatttctaa caggcggtta aatgttcaaa atttgaacac
      721 ccccctaaaa ttacagtggt caatcgaccg aattaccatt gttggaaaat tgaaagaaaa
      781 tatttattat cacacaccaa atgatgtctt gattttaaat tttgagcaat tgatgcaatt
      841 gaatgagggg aatgggtttg tcaaatcagt tggtaaaaat ggctggcaaa ttgtcgacca
      901 atacgaagaa aatatcgcgt atattgagct cttgcaattt catgaaggga aagcacgaat
      961 tgattttaat cccaataaaa ttggtcagtt tttagccagt tcgatgaaaa atttcattca
     1021 tgatttgttt ttagaacccc atttttcgcg ggcagatatc gcttgcgata tggttaatgt
     1081 tccggatgag tttattatgc aatatcgtgt ggttgacccg gtatcgttca aaccgattta
     1141 cgggcgttct ggaaaactag aatcagctta ttggggtagc cgtgccagcg aacgacaaat
     1201 tcggctatac aataaaaaat tggaacaaga aaccaaacga aaagttgtac caaaggaagt
     1261 tgagacttgg tggcggttag aaatgcaact acggcgtggc aaggcaaccg attggcataa
     1321 tatggttcaa gaaagtttga atagttttgc gagcctgcat tttttgccga ttgatacaac
     1381 acctacagat agaataatgc tcgctggttt aatgtctgat caaaatttct ggtctctttt
     1441 gtcgaggaat tcaaaatata aatatcggga attgctgaaa gaagaaagtc aaaatgatga
     1501 attgacgaat catttgcgag aaacgtttgc agaatcggca gacaatttga aac
//
LOCUS       DACBYO010000215         1451 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.224, whole genome shotgun sequence.
ACCESSION   DACBYO010000215 DACBYO010000000
VERSION     DACBYO010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.224"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..590
                     /locus_tag="IVD26_003023"
     CDS             <1..590
                     /locus_tag="IVD26_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="3-hydroxy-3-methylglutaryl-CoA lyase"
                     /protein_id="HAP6080911.1"
                     /translation="YMETGKIQEEYMEELRKFLSDKKILLIAPGKSSVDEVERIKEFV
                     TKEEVVIISVNFEYSHIDIDYVFLSNLRRFHELPKESRTKCIVTSNIQASDVYLRTSY
                     KKLLSEREVVRDNAGLMAIRFLADMNVDEIFLAGFDGYSHNEDENYGEQSMEIITKFA
                     LLDAMNVQMRDELSELAKKVKVTFLTDPRWVRIDK"
     gene            725..1303
                     /locus_tag="IVD26_003024"
     CDS             725..1303
                     /locus_tag="IVD26_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080912.1"
                     /translation="MISILCIVAYHANLRLNYNADGIIVHGSLTANQIFLNYIGIWGQ
                     LGVNCFIFISAYFLSEKRNIHFENVLGIVLECIFYSVLVYGILCACGIETFSLNSFVK
                     EILSFALGRYWFITSYLALYILSPYLNIMLNNLEKLQLQKISMLLFIGVCCYRMLFKT
                     SLFGDCAVLIALYVICYTLKKTIIIFLRDTES"
BASE COUNT          523 a          146 c          272 g          510 t
ORIGIN      
        1 aatatatgga aactgggaaa atacaggagg aatatatgga agaactgaga aaatttctct
       61 cagacaaaaa aattctactg attgcaccag gaaaaagttc tgtagatgag gtagaaagaa
      121 taaaagagtt tgttaccaaa gaagaagtcg taataattag tgtaaatttt gaatattctc
      181 atatagatat agattacgta tttttaagta atttaagacg ttttcatgaa ttaccgaaag
      241 aaagcagaac taaatgtatt gttacatcaa atatacaagc atcggatgta tatttacgga
      301 cgagttataa aaagttgtta tctgaaaggg aagttgtaag agacaatgca ggattaatgg
      361 caattagatt tttagccgat atgaatgtgg atgaaatatt cttagctgga tttgatggat
      421 attcacataa tgaagatgag aattatggtg agcaatccat ggaaattata acaaaatttg
      481 cattattaga tgcaatgaac gtgcaaatga gagatgaatt gtcagaatta gctaaaaaag
      541 taaaggtgac atttttaacg gatccacgtt gggttcgaat tgataagtag tagtaataat
      601 gtttttaaaa ttttgataaa gagatagtga gagaataaaa atgggtaaag tcttaaataa
      661 aaaagaagaa aaatatttaa gggccgatgg ggcgagatga aactctaatt ttgaactttt
      721 aagaatcatt tctatattgt gtattgttgc ttaccatgct aatttgcgtt taaattataa
      781 tgcagacgga attatagtac atggttcatt aactgctaac cagattttct tgaattatat
      841 tggtatttgg ggtcagctag gagttaattg ttttatattt atttcggcat attttttaag
      901 tgagaaaaga aacattcact ttgaaaatgt tttgggaatt gtattagaat gtatttttta
      961 tagtgtatta gtttatggaa ttctttgtgc atgtggaata gaaacatttt cattgaacag
     1021 ctttgtaaaa gaaatattat catttgctct aggtagatat tggtttatta catcctattt
     1081 agcattgtat attctaagtc cgtatttaaa tatcatgctt aacaatctgg aaaaacttca
     1141 gttgcaaaaa ataagtatgt tattgtttat aggtgtatgc tgttatcgta tgttatttaa
     1201 aacatctttg tttggggatt gtgctgtttt aattgcacta tatgtcatat gttatacact
     1261 gaaaaaaacg ataataatat ttttgagaga cacagaatca taggaacaat tgtatgtata
     1321 acagttatac cacttctcat atccatagga atacttttca aatttatacc aaatgcaatg
     1381 gttaaccaga tggttcatat tggttctcca ttgatggtta tagcaagtat atttttattt
     1441 tatgtattta a
//
LOCUS       DACBYO010000216         1445 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.225, whole genome shotgun sequence.
ACCESSION   DACBYO010000216 DACBYO010000000
VERSION     DACBYO010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.225"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            111..1253
                     /locus_tag="IVD26_003025"
     CDS             111..1253
                     /locus_tag="IVD26_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP6080913.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            1246..>1445
                     /locus_tag="IVD26_003026"
     CDS             1246..>1445
                     /locus_tag="IVD26_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAP6080914.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDA"
BASE COUNT          463 a          257 c          333 g          392 t
ORIGIN      
        1 ccccaaacct gtgagtagta atgagaggtt ttaagaagat agtacatatc acactttttg
       61 aaaggtggtt tacaggtatt tcaaggctat tgtgggattg gaggaataca atgaacaatt
      121 tagaatttgc acttgaaatg aagaacaaac gtcttgccag cggtctttca caaggagaac
      181 ttgcaagtct tacccatgta tcaagatata gtatcaaccg ctttgagaac ggaaaagcta
      241 acgccagcaa ggaaacacag aacattatcc tgcgttgtct gaattactat atctgcgata
      301 agccttttta tctgctcgtt gattatctgt ctgtccgttt tccaacgact gacgcattgg
      361 aagttatccg aaaggtgctt ggcatgaaag cagattattt tatccattat gactatgggt
      421 attatggcta taaggagcat tatgcttacg gggaaatcaa ggtcatggct tctgatgatg
      481 aacacatggg cgtattttta gaattaaaag gggcaggctc acgcaacatg gaatatgtct
      541 tacaggcaca gaacagggac tggtattcat tcttaaaccg ctgtcttgac tgtggcggtg
      601 ttatccgacg ttttgacttg gcaatcaatg atatgtgcgg tctgctggat attcctgtgc
      661 tatctgaaaa atacagaaat ggtggtgcgg aatgtcgctg taaaaactat gaaaatgtac
      721 aaggtggaaa attaagcgga aaaaaccgta atttagcaag taccctttat atcggctcaa
      781 aggcaagcac aaaatatttc tgcctgtatg aaaaacaaaa ggaacaggca acgaaaaaga
      841 aacataccga tattatcaac cgttttgaaa ttcgtctgcg tgacaaaaag gcggtacagg
      901 cagttgaaga actgttattg acgtataacc ctcatgggct ggtgttttat ctcattaccg
      961 attttgtgga atttcctgac tatccattgt gggagatatt catttcccat gacagtttac
     1021 cttttgaaat gaaccctgta cctgtcaata tggaacgcac tctgcaatgg ctggaaagac
     1081 aggtcatgcc gtcaatcgtg atgatagagg aaatcgacag gctgacaggt tcaaactaca
     1141 tgaaaatgat tgatgaatgt acccaccttt ctgaaaaaca ggaaatgctt gtggaacaga
     1201 tgtgtacgga catatcagac gtaatcgaaa gtgagggggt gttttatgag taatacacag
     1261 gatattcccg tatgggaaaa atacaccctt accattgaag aagcgtcaaa gtatttccgc
     1321 attggagaaa acaagttaag acgattggca gaggaaaaca aggacgctgg ctggctcatt
     1381 atgaatggca accgcataca gattaaacgc cgacagtttg aaaaggttat tgataaattg
     1441 gacgc
//
LOCUS       DACBYO010000217         1443 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.226, whole genome shotgun sequence.
ACCESSION   DACBYO010000217 DACBYO010000000
VERSION     DACBYO010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1443
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.226"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            90..1430
                     /locus_tag="IVD26_003027"
     CDS             90..1430
                     /locus_tag="IVD26_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP6080915.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
BASE COUNT          457 a          318 c          282 g          386 t
ORIGIN      
        1 actttttctt ttttctaata aacgcaaaca gacaccttga aatcctttag aataaagtcg
       61 acgaaaacca ttcaaaggag tgtttcaaga tgtcctattc agagtttacc aaagagttac
      121 tagatattct agacctaaat cttacctttc atgaagatgc ctttcgcaaa gagcgcatta
      181 atgacgaaac atgttttgtt tttgatggca cattgaccta tcaaccagag gaatgcttcc
      241 attgccacta tcaaaataag caaacgatca ttaaatgggg ctggaaaaaa gtatccatct
      301 tattgaatga tgtcagtaac tacaagacca ttgtgcggat taacaaacag cgcttcaaat
      361 gtaaacactg tggaaagact tttttagcag aagattcagt tagcgatcgt cgctgctcca
      421 ttgcccgcag agtcaaacaa gccattcttg agctattaag tgagcctatt tctatgtctt
      481 tgattgcacg tatgaagcac atttctccga ccactgtcat tcgaatactt cgcagccttc
      541 ggcctaaaac cgtttctttg aaccagccgt taccagaagt ggtgtgtttc gatgaattca
      601 aatcggtgaa aaacgtctcg ggagccatga gctttgtcat gatggacggc aagacccatc
      661 aactgattga tattgtggaa aatcggcaac tcaatccttt acgcgactat ttcttgcgct
      721 accctagaaa agtccgtgaa caagtacgtc tagtggtttc agatttctat acaccctatc
      781 gcacattggt gaaagagtgt tttccgaatg cccgaatcgt cgccgatcgc tttcatatta
      841 gccaacacat cggtcgggcc tttaccaacc accgaattca agtaatgaag acctttaaaa
      901 aaggggatcg tcggtcgaag cacttaaaga aatactggag actacttcaa aagaatgcgt
      961 gggaattgaa tggtcagcat cgctactggc gtccgtcatt tcgagatcat ctgacagaag
     1021 cggagatagt cgatcggcta ttatattatg atgactcctt aaagcgaggc tacgaagtct
     1081 accaggtttt tctttccgct atcagaagac aagatgttcc tgaattcgtc gcgctcctaa
     1141 aagaagacta caaggagttg ccagagcact atcaaccagt gttcacgacc ttcaagaaat
     1201 atcgaacaga aatcaaacga gcgttgcgag ttccctattc caacggccct atagaatgtt
     1261 tgaacaacca tatcaaagta ctaaaacgaa ttgcctatgg ctttagaaac tttcaaaact
     1321 accgagaacg aatcttttta tatcgaggaa aatatttcaa gaaaactaag aacactaccc
     1381 aactgactaa agccagaaca acaacacggc tagacaagat agctgtctag ccgtgtgagt
     1441 atc
//
LOCUS       DACBYO010000218         1440 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.227, whole genome shotgun sequence.
ACCESSION   DACBYO010000218 DACBYO010000000
VERSION     DACBYO010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.227"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(543..>1440)
                     /locus_tag="IVD26_003028"
     CDS             complement(543..>1440)
                     /locus_tag="IVD26_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6080916.1"
                     /translation="VSLILSSILGFFLSSYFLKPLKVLRDTMDTIRKDPQSDIHMPEI
                     DTNDELADLAEIFNEMLDRMRLYIEQQEQFVEDVSHELRTPVAIIEGHLSLLNRWGKD
                     DPEILEESLSASMQEISRMKSLVQEMLDLSRAEQVDVHYANETTKGKEVTYQVYNNFK
                     ILYPDYVITLDDDLTKEVTLQIYRNHFEQLIIIILDNAVKYSTTRKEVHISISSTLNE
                     FEIAIQDFGEGIPKEDLNKIFNRFYRVDKARARTKGGNGLGLSIAKQLVENYKGRILA
                     ESVVGQGTIFRIFIPIAKAEDK"
BASE COUNT          430 a          265 c          200 g          545 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
//
LOCUS       DACBYO010000219         1426 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.228, whole genome shotgun sequence.
ACCESSION   DACBYO010000219 DACBYO010000000
VERSION     DACBYO010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1426
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.228"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..750
                     /locus_tag="IVD26_003029"
     CDS             <1..750
                     /locus_tag="IVD26_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP6080917.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDE
                     FFIQSVASKRNNIPRKSLDYRTIIEHLWKYF"
BASE COUNT          492 a          207 c          298 g          429 t
ORIGIN      
        1 aaatcaaact gtggtagacg tccgcttgtt ttacccgagg aacaatcaga atatattcaa
       61 agaaaggttg ttcaaggatg gacacccgat gtgattgttg gtcgtgcagc gtttcctatt
      121 agttgttctg ctcgtaccat ttatcgtatg ttcaaaaagg ggctatttga ttcttctgac
      181 ttaccgatga aaggcaagcg taaaccgaat ggacatcaag aaagacgtgg aaaacaaact
      241 ttccgccgct ctattcatga acgtgaaaag gattatagcc aattctcaaa tgagtttggt
      301 caccttgaag gtgacactat cgtaggtctg aaacataaaa gtgctgtaat taccttagtt
      361 gaacgattat caaaagttat catcacattg aaaccgtgtg gtagacaagc gattgatatt
      421 gaaaaaaaat taaatcaatg gtttgaatct gtaccgaaaa acctattcaa atccatcact
      481 tttgattgtg gaaaggaatt ttcaaattgg aaacagatca gtaatgtcaa tgatattgcc
      541 atttatttcg ctgatccagg aacgccgtct caaagaggcc taaacgagaa ttctaacgga
      601 ttgttacgta gagatggttt attgaaatct atggatttca attcagtaga tgaatttttt
      661 attcaatctg tcgcatctaa acgaaataat attcctagaa aatcactgga ttatcgaacg
      721 attatcgaac acctttggaa gtatttttga gttacgtaag tattgatgat ctgtctaatt
      781 taatttgaca attaagaaag tattaacttg ttttgtgaaa aagagaattt gaaaaacgat
      841 tggcgaacaa atgctcggta ggtatggtat aaatacagag ctaattggtg tgatgaaatc
      901 agatattcgc gtgagattca gtaaagtagg agttcgaaaa cagctaggtg acaaacagta
      961 ttgctttggt acttcggaat ggtttatcaa attcttatca acagttcact tctctttatg
     1021 tttgagtgat gattcgttag gttattgctt ggaaagaccg gatgagagta gaagagttta
     1081 attttataaa gtgaaaagag gtaatgtacg atatacgtag ggctgaacca atagaggata
     1141 agcaaacgat gttacaggcg caaaattcat agcttactgt tttggagata acagaagagg
     1201 aaataatgca gaagtaaggc gaaaaaagga cggaagccta acagcatatg aaataaagaa
     1261 aaatattata actactgata aatcggtatt gagcaaagta ctaataggag tcaaaaacat
     1321 tcataagcta tgagtgtttc ttggctactt ttttattttt atgtatctac aaaagtttcc
     1381 aggggcagaa cctgtgatta ttaatggaag aacctcaagt attgtc
//
LOCUS       DACBYO010000220         1424 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.229, whole genome shotgun sequence.
ACCESSION   DACBYO010000220 DACBYO010000000
VERSION     DACBYO010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.229"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(150..1337)
                     /locus_tag="IVD26_003030"
     CDS             complement(150..1337)
                     /locus_tag="IVD26_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAP6080918.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DACBYO010000221         1392 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.230, whole genome shotgun sequence.
ACCESSION   DACBYO010000221 DACBYO010000000
VERSION     DACBYO010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.230"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            122..1339
                     /locus_tag="IVD26_003031"
     CDS             122..1339
                     /locus_tag="IVD26_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP6080919.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKEALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
BASE COUNT          458 a          306 c          258 g          370 t
ORIGIN      
        1 cttctttact gtcattttag aatcaggttt acgtatgttg gggccatgag cccgtgtata
       61 ggaaattgga atcgaaatga agcagtaaag ttctttcaaa acttaaaaag gaggaaaaca
      121 aatgccttac attcttgcat tagatgtttc aatgggacac agctacagtg tcctatacaa
      181 agacgacacc tgcttatttg aagacgagat cgaacacact caaagaggat ttcatgcatt
      241 actcgaagag atccagcact tgcctgaacg tccattgatt gtttttgaag caacggggat
      301 ttattccaga ccagtcgaaa agttctttca agatcatcac ttttcttact gtttgttaaa
      361 cccgttagaa gcgaaaaaac agatggaaga aaacacctta tgcagttgga aaacagataa
      421 atcggatgcc catcggctcg cacagactca tcttaaaaat caacgtcagc caaaagaagt
      481 acaaagcaat ttttacttag agatgcgcga tttagcccgt ttttatcaag aaattgagaa
      541 gaaaatcact cgtctgcgca tggatttaca caactgcctt cagttgactt ttccagagct
      601 tgaacagttc tttttaaaca ggctgacccc ttacgcattg atattgatcc gtctttttcc
      661 ccatccagat tttgtattgg catctactcg gacaaaaata aaaaataaac tgatcaacga
      721 aacacggaaa aaaatctccg cgaatcgtgc cgagcaaaag gcagatcaaa tcatccacta
      781 tgcacagtgt gcctatccag ctgttgaaaa agacagtatc cactgtcaaa aaacgatcta
      841 ttacgctgaa cttctccaag atttactcga acaaaaagaa gcactggcga cacaaatgat
      901 caaaaaagcc gaaggctctc cttgcttttt gttgtaccaa acgttccctg ggattggcgc
      961 actcacagcc gctttattgc tcggtgaatt aggagatatc acacgattta aaacccataa
     1021 acaattgaat gcctttgtcg gaatcgacat ccgacggtat cattcaggta agtatactgg
     1081 ccaagaccgc atcaataagc gtggtaatcc caaagcacgg aaaattattt tcttcaccat
     1141 tcgaaatatg attcgccagc aacgcgcagc tcctaatcat attgtcgatt attactacaa
     1201 attaaaaaag caacctatcc ctaagaaaga taaggttgcc acagttgctt gtatgaacaa
     1261 gcttctgaaa tgtatgcacg ctatggttag ggcacataca gagtacgact atgcgtacgc
     1321 ggtctcagtg gaccattaac taaaccactt acagtatacc acttctttgc ccagatcgaa
     1381 aattttttac ga
//
LOCUS       DACBYO010000222         1389 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.231, whole genome shotgun sequence.
ACCESSION   DACBYO010000222 DACBYO010000000
VERSION     DACBYO010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.231"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..1343
                     /locus_tag="IVD26_003032"
     rRNA            <1..1343
                     /locus_tag="IVD26_003032"
                     /product="23S ribosomal RNA"
BASE COUNT          384 a          300 c          414 g          291 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc catttcttta agaaagtaag atccctgaga
     1261 gatgatcagg tagataggtc aggagtggaa gtacagtgat gtatggagcg gactgatact
     1321 aatcgatcga ggacttaacc aataggttaa aagaaaagaa ctcggaaaaa aacttatgtg
     1381 acttcaaat
//
LOCUS       DACBYO010000223         1387 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.232, whole genome shotgun sequence.
ACCESSION   DACBYO010000223 DACBYO010000000
VERSION     DACBYO010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.232"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            5..403
                     /locus_tag="IVD26_003033"
     CDS             5..403
                     /locus_tag="IVD26_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAP6080920.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1082
                     /locus_tag="IVD26_003034"
     CDS             387..1082
                     /locus_tag="IVD26_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAP6080921.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
BASE COUNT          527 a          205 c          274 g          381 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcatgcgat aacgttaggt aaagagctac
      961 tagatcaagt attagagatg ccctcgattg ataaagcagt gaggggcttc caagaagatt
     1021 gggtgcaaac tttccaagca gaaacgattg gtgaactaaa aaaggtcgct gattacttct
     1081 gaatcaattt ctccataaaa taaacgatag ccttctcgaa aactcgagga ggctatctga
     1141 cgattcaata ttcattaatt taaagtttgg gtgactatta ctaactatta cttatttctc
     1201 atttaaacga tgtattccct aacctctaat acatccttgt aactctgaag ttacgccagt
     1261 tttgaataaa tttcataaaa acaaatgaaa agtgtcgcat aaaaatatct ttcgtgtttc
     1321 tctagtataa cagaataaga agaacaagtc cagaagggat atttttagtc ttttttaaaa
     1381 taacttt
//
LOCUS       DACBYO010000224         1379 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.233, whole genome shotgun sequence.
ACCESSION   DACBYO010000224 DACBYO010000000
VERSION     DACBYO010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1379
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.233"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(141..1199)
                     /locus_tag="IVD26_003035"
     CDS             complement(141..1199)
                     /locus_tag="IVD26_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAP6080922.1"
                     /translation="MVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPGLLARQGF
                     IEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQIFYITLSS
                     SRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFSFGTNYAK
                     DFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIWKAALKVI
                     RPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLVSSGIIAF
                     ICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFNKRDVISI
                     VFWYYLGSISYLYLKKEN"
BASE COUNT          543 a          226 c          164 g          446 t
ORIGIN      
        1 tacgctcact atatcttcta gcgttttcaa attcagaata aataaataaa tctccttttg
       61 attctcggta aaaattttga taaacattta atatattaat caaatgtaaa ggagtccaag
      121 caatgaaagc tgtcttcata ttaattctcc ttttttaaat acaagtaaga aatgcttccc
      181 aaataatacc agaaaacaat tgaaatgaca tcgcgcttat tgaaaagtac atgagcctcc
      241 accatttcat ctataaaaat agatagtata aaaattaaaa caataccaag aaacgcataa
      301 ttcactttac ttctaaaaaa tgttttgagt aaactaaaga tatttaacac atagaaagca
      361 tagatacata taaaagcaat tataccactt gatacaagta cttgaagaaa tccattatgc
      421 atgtttccat gtgctctttt tagttcattc acatctgtag tatcaagatc tacttttttc
      481 aaaaattttg catcgctatt cccatagaaa tcggtctctc cataaccaaa taacaaagtt
      541 ggtcttataa ctttaagcgc agctttccaa atcgtaaaac gaccagctga aatttcggag
      601 ttatcactag aatgctgtaa tattacttct ttttctggaa gtggagtttt atctgattca
      661 tttgactcta taacttctac ttttctatca atcgatacag gaattgttgc taaaaaatcc
      721 ttagcataat tagtaccaaa agaaaaatat accaatagaa ctaataatat gcttaccatc
      781 catttgattt ttacaggtag tacttctcta atgctctttc taaattttga attggcaaac
      841 aacaaaagaa ataatactaa aaaagaacaa attactacct gggcacctct agacgaagaa
      901 agtgtaatat aaaatatttg tacgataaaa ttcatcatat aaaaaacacg aatcgttttt
      961 gttatttttg aaattaatac actaattaaa cttaaaataa tagaagtata tccaaacata
     1021 gctccaacat ttggacttgt atagacacca aataaccgat gttcaataaa accttgtctt
     1081 gcaagtaatc ctggcgttcc tgttgggaca tgataagaaa tcaaaaaaat aaattgatag
     1141 atagatatta gcgcagctaa aaaaattatg ataatgaaaa cattattaaa atacaccatt
     1201 tttttctttt tttcctcttc actttgtgaa aagtctgcag gaaaaattac tatcaaagta
     1261 atcagcaaat atccaaaatt ataaatagat ggaattaaaa aattttctct gttaatgatt
     1321 atagttaaga taaaactaat cattgctcca atcagtagcc aagaaaaacg cattttaaa
//
LOCUS       DACBYO010000225         1377 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.234, whole genome shotgun sequence.
ACCESSION   DACBYO010000225 DACBYO010000000
VERSION     DACBYO010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1377
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.234"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            185..523
                     /locus_tag="IVD26_003036"
     CDS             185..523
                     /locus_tag="IVD26_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6080923.1"
                     /translation="MNGIEDENLRRLINSLVIELYKYQAESERKKIKERQAQGIEIAK
                     KKGKFKGRQLKFKKNDPRLKHAFDLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVD
                     QRKNNEKRDS"
     gene            615..1356
                     /locus_tag="IVD26_003037"
                     /pseudo
     CDS             615..1356
                     /locus_tag="IVD26_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          523 a          216 c          269 g          369 t
ORIGIN      
        1 ttttcatgat agatttttaa atatctcaat ctatctccaa aattagttgc ttttgtagct
       61 atagttgact atgaatatga caaataatta gaaaaaactg tgccaattaa atatcaaaat
      121 gacaaattga tgaatcaaat tcaaattaag gggggcaacc ctggaagtct taaatttacc
      181 ctcaatgaat ggtattgaag atgaaaattt aaggcgtttg attaatagcc ttgtcattga
      241 attgtacaag tatcaagcag aatcagaacg aaaaaaaatt aaggaacgtc aggcacaagg
      301 aatcgaaatt gctaagaaaa aaggcaaatt caaaggtcgg caactgaaat ttaaaaaaaa
      361 tgatccacgt ttaaagcatg ctttcgattt gtttttgaat ggtttatccg ataaagaagt
      421 tgaagaacaa actgggatca atcgccgaac gtttagaagg tatcgagcaa gatataacgt
      481 gacagtagat caaagaaaaa acaatgaaaa gagggatagt taatgagtac ggttatttta
      541 gctgaaaaac aagccaggca ttagcctacg caagtgcttt aaaacaaagc accaaaaaag
      601 acggttattt tgagatcaaa gacccactat ttacagatga aacgtttatc acctttgatt
      661 ttgggcattt agtggaatta gcagaaccag gtcattatga cgaaaagtgg caaaattgga
      721 aacttgaatc tttgccgatt tttcctgatc gatacgattt tgaagttgca aaagataagg
      781 gaaagcagtt taaaattgtt gcagaacttc tcaaaaaggc aaatacaatt attgttgcaa
      841 cagatagcga cagagaaggt gaaaatatcg cctggtcgat tatccataaa gcaaatgcct
      901 tttcaaaaga taaaacattt aaaagactat ggatcaatag cttagaaaaa gatgtgatcc
      961 gaagcggttt tcaaaatttg caaccaggaa tgaattacta tcccttttat caagaagcgc
     1021 aaacacgcca aattgccgat tggttgatcg gcatgaacgc aagccctttg tatacgttaa
     1081 atttacaaca gaagggcgta caaggtacat tttcactagg acgtgttcaa acgcccacct
     1141 tataccttat ttttcagcgc caggaagcta gtataaaagt aaaacaaggg tcatttaagg
     1201 gcgttctaag ccccacacag cgttttaaaa cccaagagga gcttttttgc ttttgtttct
     1261 tctaaacaag ctaaaatagg caatcaagag gggataattg ctgatgttca aaccaaagag
     1321 atggataggc tacaattaac tagacagaaa aattaaggtg tgtagactag aagaaaa
//
LOCUS       DACBYO010000226         1362 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.235, whole genome shotgun sequence.
ACCESSION   DACBYO010000226 DACBYO010000000
VERSION     DACBYO010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.235"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            82..>1362
                     /locus_tag="IVD26_003038"
     CDS             82..>1362
                     /locus_tag="IVD26_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAP6080924.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          464 a          262 c          257 g          379 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat ta
//
LOCUS       DACBYO010000227         1333 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.236, whole genome shotgun sequence.
ACCESSION   DACBYO010000227 DACBYO010000000
VERSION     DACBYO010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1333
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.236"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(23..352)
                     /locus_tag="IVD26_003039"
     CDS             complement(23..352)
                     /locus_tag="IVD26_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP6080925.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(429..701)
                     /locus_tag="IVD26_003040"
     CDS             complement(429..701)
                     /locus_tag="IVD26_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP6080926.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(701..964)
                     /locus_tag="IVD26_003041"
     CDS             complement(701..964)
                     /locus_tag="IVD26_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP6080927.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            1198..>1333
                     /locus_tag="IVD26_003042"
     CDS             1198..>1333
                     /locus_tag="IVD26_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP6080928.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     L"
BASE COUNT          425 a          257 c          172 g          479 t
ORIGIN      
        1 gacatgtttt gaaggaacga tttcataagc caatttctgt tgccaactcc tctttagtca
       61 ttactttaga attagtaagt gtatcttcag caatatctct aaaggaagaa tgcattttgt
      121 tttttctatt cttaaattct acaagaatct catctttatc gtagccttct gcaattatat
      181 cagacaaaat atcttcgcta aaatcataaa attctttttg tggttcaaca aattcataaa
      241 gaataccatt ctctaccaac tttgcttcaa cttcgactcc attaggaaca ttaaaatctt
      301 taggtactgt caacatgatt gaattgcctt gttttcttgt ttttgtaatc atttaaatcc
      361 ctcatttcta acagtatgta attacttagt aaatacatta taccacgaga taatgtattt
      421 acaagtaatt actgtgactc gtaatgcgtc cttgctgaat aaatttcaac cacgtgttca
      481 tcttcatcta ccttataaac aacccggtgt tgtctattca atcttctaga atacctacct
      541 tcatgtgtag gttttaactt ctcaaatgat tgggtaggga gatagggatc ttcctttaaa
      601 gtctgaataa ccttctcaaa ttgaggtttc aaattagact gtttgatttt ctttaaatca
      661 gctttagccg agtttttaat catcacagaa tagttattca ttataagtta tcccaatcaa
      721 tttcatcaac attagtaaat ccactatcat ctttttctcg cttacgaaca acacccaaag
      781 tgcctatttg ctcaagtaat agcgtttctt tgattgcttt ccaatcatcc aaaccaataa
      841 gcaccgcatt attttcactg cgctcactaa tgatttcaat ttccgtatga ttctcattta
      901 catctttcaa caacttataa aaatttttcc gtgctgagct aggatttaag actgtttttg
      961 ccatatctac tccccctcta atttatatct ccattctaac gtacttaatt aagtacgtaa
     1021 attcgattgt tttgtttaaa ttggagtacc aaaacagcat tgtaaagtgt tatccgtttc
     1081 ctttataccc gtggtgctag ttaatttttt cctagaggaa aatgtctaaa catgttggta
     1141 aatcaacaaa aaaacgcata gagtagtctc aaaactccca agaaatgagg actacatatg
     1201 cgttcatcaa aatatactga acattataca gatactttta taacattcaa ggaaattatg
     1261 agaactgttt ctaacatata ccacaattgt gtaccagata agattaaaaa ccgaagaaat
     1321 actgatcaac tga
//
LOCUS       DACBYO010000228         1305 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.237, whole genome shotgun sequence.
ACCESSION   DACBYO010000228 DACBYO010000000
VERSION     DACBYO010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.237"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            289..696
                     /locus_tag="IVD26_003043"
     CDS             289..696
                     /locus_tag="IVD26_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080929.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            710..1111
                     /locus_tag="IVD26_003044"
     CDS             710..1111
                     /locus_tag="IVD26_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080930.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1113..>1305
                     /locus_tag="IVD26_003045"
     CDS             1113..>1305
                     /locus_tag="IVD26_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080931.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQ"
BASE COUNT          494 a          159 c          224 g          428 t
ORIGIN      
        1 tttgagggga agtacatata gttgttgata tagttgctaa tattgttagc taatttgtta
       61 gtaaaactgt atacgaattt agatagtaaa aaaacagttt gttccttata tagaggcact
      121 tttactactg attaaatgtc agatatgctt acaaatatac ttataaatat gcttacaaaa
      181 ttagctaata tttccgttga caaagctttg ttactattgt taaactaaat tgactagcaa
      241 aagtgaaaca taaatttatt aaataaatgt aaaaattagg agaaatcaat gtcttataga
      301 gtacaattaa taatttcaga agatgtagaa agtcagcaat ttggcactaa tgttattaat
      361 aaagtaatta atccagctct ttctattaat gcgcctttaa ttcctactgc tttatcattt
      421 tctgtaacag ctgtggtgtc tgagatagag gatacagaaa agataaaaat agtagaaatt
      481 gaagttttaa acaagaatga aaaacaaatt ttttctacgg gtgaagtatc ggtaagcttg
      541 cctcctcaag ttaacgatat aaactttaat ataaacgcca gaaatgtctt ggttgaagaa
      601 gcaggagagc attatgctgt tgttaaattt aatggaactg agattggaag gcaaatcttt
      661 gatatcaagg tcaacaaacc agtggaaaaa aattaaggag acgatacgga tgcttgatat
      721 agtaccatca aatacacatc ggagtggtag cttaataaat tttgctgcga tttttgcttg
      781 cgcatcggta attctagcat ctccagttgt tgtggatgca agttctactc cgaaaactaa
      841 aaatgataat caacttgtaa ttactacaaa aaatgagatt aacacaattt caagtaatga
      901 tggcaaaatt tttgatgtga taaatacggt tttaaaaaga aaagctgaaa tcaatataaa
      961 atatgatgaa gatttaaact tgtatttctt tgttatcaaa acaacatctg aattgttttc
     1021 ctcagattac gatgttttgg atactctcga taatgtatta tctgactata aatatatggg
     1081 gaaatctgta gtagcaactt tgggggaata aaatgtttga ctttaatgaa tatttatcta
     1141 tttccaaaca aattgaatca gatgataaat ataattctaa agaatcttat agaagaactg
     1201 ctgtttcaag agcatactac agtgctttta aaaaatctga tgagtatttg aaagaaaatt
     1261 atgatattat ttataatgga agtagcggaa aaggaagcca ccaaa
//
LOCUS       DACBYO010000229         1292 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.238, whole genome shotgun sequence.
ACCESSION   DACBYO010000229 DACBYO010000000
VERSION     DACBYO010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.238"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            276..>1292
                     /locus_tag="IVD26_003046"
     CDS             276..>1292
                     /locus_tag="IVD26_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080932.1"
                     /translation="MIIVRLFLSKQIKNDIKFVVVNLVKAVFLTCALTSYFWYPMLQQ
                     MNYQEIHSPFKTDLQLEALSISDSIIQALNNDITTYTMGLLGLVALIFPLFILKEMEK
                     KEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQFPWRILGIQIFFSSMIITLVFMKK
                     TMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQSKHGHIVINEETLPRYTTSDMGGL
                     YDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAADNNITYTVASNKKQKVTVPVYAYL
                     GTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEITTKYTPTALMALWISILTYCLVVY
                     SSFKR"
BASE COUNT          443 a          193 c          231 g          425 t
ORIGIN      
        1 gtttttatta tggagaaaag ttttttaaaa agatagatgc tgctttttta tttagttgtt
       61 tatatacttt tgcaacttat cgaacagttg atatctatta tcgatccgca attgcagaag
      121 caatcgctct tacgattatc ccagctgttt tatattatgc ttatggattg atattcaata
      181 gagaaaaaaa agtcatcgct ttatctgtca gtataagtct acttgtgtat actcatgtct
      241 taactacact attgtgtagt gcattgattg cttgtatgat tatagttcgt ttgtttttaa
      301 gcaagcaaat aaaaaacgat ataaaatttg tggtcgtgaa tttagtaaag gctgtttttt
      361 tgacttgtgc attaactagc tatttttggt atcctatgtt gcagcagatg aattatcaag
      421 aaatacacag tcccttcaaa acagatttgc agctagaagc actttctatt tcagatagta
      481 tcattcaagc gttaaataac gatattacaa catacactat ggggttatta ggattggttg
      541 cgttgatttt tcctttattc atactgaaag aaatggagaa aaaagaaaaa atcatctatg
      601 ttggcgtagt ttctacatgg gtatgcgtaa ctaatttatt tccatggttt ttgtttcaaa
      661 aaacaccgat aagcttgctc cagtttcctt ggcgtatctt aggtatccaa atcttttttt
      721 cttcaatgat cataacgctt gtttttatga aaaagactat gaataaaaaa tattcatggt
      781 taatcattgg cgctactgtg gtgtttctac tcgtcacgtc tatagcagca aaagaaaatt
      841 acgcaaaagt tatccaatca aaacacggtc atattgttat caatgaagaa acactcccac
      901 gttatacaac atcagatatg ggaggattat acgattacgc cccaacagaa gcgataaaag
      961 aaaggcctca cttagaaaaa catgaagtaa aagtaggaga atcgtgggaa aaagggaagt
     1021 ataaagctgc agataataac attacttaca cagtggcaag caacaaaaag caaaaagtga
     1081 cagtaccagt atatgcttat ttaggtacac aggtaaaagt aaacggtaaa gtcgtaaatg
     1141 actcttataa aaaacatggc ttagtgaatg tggatgtaaa tgctggagaa aataagatag
     1201 aaattacaac aaaatatact ccaactgctc tcatggcttt atggatcagt attctgactt
     1261 attgtttagt ggtgtattca agttttaaac ga
//
LOCUS       DACBYO010000230         1245 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.240, whole genome shotgun sequence.
ACCESSION   DACBYO010000230 DACBYO010000000
VERSION     DACBYO010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1245
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.240"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            102..>1245
                     /locus_tag="IVD26_003047"
     CDS             102..>1245
                     /locus_tag="IVD26_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP6080933.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQ"
BASE COUNT          387 a          242 c          243 g          373 t
ORIGIN      
        1 ggtgaacttc accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc
       61 tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat actcagctta
      121 tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta
      181 aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag
      241 aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa
      301 ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac
      361 aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa
      421 aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata
      481 cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca
      541 tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct
      601 ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatggacg
      661 gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat ttagaacgct
      721 atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt attgatatgt
      781 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
      841 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      901 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      961 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
     1021 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
     1081 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
     1141 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
     1201 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaa
//
LOCUS       DACBYO010000231         1223 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.241, whole genome shotgun sequence.
ACCESSION   DACBYO010000231 DACBYO010000000
VERSION     DACBYO010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1223
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.241"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..1173
                     /locus_tag="IVD26_003048"
     CDS             <1..1173
                     /locus_tag="IVD26_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAP6080934.1"
                     /translation="DIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEKEGLSSFKKA
                     IVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRDNITNWHIKA
                     VQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKDSQHPIVYYH
                     HDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFFEAIPKGKKN
                     TDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWMATIDPVAKS
                     KLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHSTSLEGARTS
                     GIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDVQQHFSRN"
BASE COUNT          397 a          220 c          264 g          342 t
ORIGIN      
        1 gatatcggac ggacaaaagt acgagaagaa attcgtttcc atcaggctat gttggattgt
       61 ctcacccatt atcaacatac ctattgttgt aaaagctgcg aaaaagaagg actttcttct
      121 tttaaaaaag cgatcgttcc taaacctttg atttctaata gcttaggttc caatagttta
      181 gtggcggaaa cgatccggat gaaatttggt cagaaagttc ctgcctatcg gcaagagaac
      241 tattggaaac aaacacatgg gttggatatt tcgagagata atatcaccaa ttggcatatt
      301 aaagcagtgc aaaacgcgtt agacccttta ggagaacgat taagagtcta tcttaatcaa
      361 gaagagattc tacacgggga tgaaacaagt tatcgtgtga ttgaaagtgc caaaacagat
      421 acctattact ggcagttttg tacaggaaaa gacagtcagc atcccatcgt ttattatcac
      481 cacgacgaaa gtcgtgctgg agatgttccg aaaacttttc tcaaggagtt tacagggtat
      541 ttacactgtg acggctatag cgggtataat gccgtggaaa gtgtacgact tgtctattgt
      601 ttcgcgcatg ttcggcggaa atttttcgaa gcaattccaa aaggaaagaa aaacacggat
      661 attcccgcag ctcaagcagt caaacaattg gataaatggt ttgtcctaga aaagaaatgg
      721 aaagactttt ctcctgagaa gcgattaagc tgtcggcaac aagaactgcg tccattattt
      781 attgcttttt atgagtggat ggcaacgata gatcctgttg caaaatccaa gttggatgca
      841 gccgttcaat atgcgtgtaa actacgaagt ggttttgaac ctatttttga agatggtcgt
      901 ttagaactca caaataatcg tgcggagcga aatatcaaag agctggtgat aggacggaaa
      961 aattggttgc attccacaag tcttgaagga gcacgaactt caggaatcat tctgagtgta
     1021 tataaaacag cagaacttaa cggattgaat cctgtaaagt atctagagtt tctatttgat
     1081 aagataccaa atcttcccgt actttcagca gaaactttag atcaactgtt gccttggaac
     1141 aaggatgtac aacaacattt ttctcgtaac taaaaacgcc aaacattccc gattctattc
     1201 tataggtcgg gttatttgac gta
//
LOCUS       DACBYO010000232         1206 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.242, whole genome shotgun sequence.
ACCESSION   DACBYO010000232 DACBYO010000000
VERSION     DACBYO010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.242"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..1161
                     /locus_tag="IVD26_003049"
     CDS             <1..1161
                     /locus_tag="IVD26_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP6080935.1"
                     /translation="SNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNIN
                     VNLESDSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFS
                     AIISLIYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLR
                     TIDDLEFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYI
                     NECIEIVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVN
                     NYILDENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISN
                     MDKIFDVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
BASE COUNT          548 a           86 c          164 g          408 t
ORIGIN      
        1 agtaatatga atggaaaaga aataaaatat atagaacaaa ctttggagtt ttattccaag
       61 agtagtgaaa taaaagtatt cataaaagaa aaaaataata agaatgaaat acaaatcaaa
      121 gataatataa atgttaattt agaaagtgat agtaattctt tgataattga agaaagagaa
      181 ataaagctta atgatggtaa aaaaacaaat ctacaatttg tttctacagc tgatatgcaa
      241 aaagatgcga aagatttaag ccttaaattt ttaccatatt ctttattaat atcaatttta
      301 ttttctgcta ttatttcttt aatttatgca aaatcaataa aaaataatat acaagaaata
      361 aaaattgtta ctgataaaat gatgaaactt gataaaaaaa tgagtttaaa agttagctct
      421 aatgatgaag ttggagaatt aaaacaacaa attaatgatt tgtattctac tttattaaga
      481 acaattgacg atttggaatt taaaaataaa gaaattttaa aattagaaaa gttaaaatat
      541 gactttttta aaggtgcatc ccatgaactt aaaacccctc ttgctagtct taaaataata
      601 ctggaaaaca tgaaatacaa tattggaaaa tataaagaaa gagatattta tattaatgaa
      661 tgtattgaaa tcgttgatag tttaacaaaa aatatttctc aaatattatc agttcattct
      721 atagaaaatt tgaataatga tgaagaatat ttgaaaataa atgatacatt agaagacata
      781 ttaaaaaagt atgaaatatt agcaaatcaa aagaaaataa ctgtcaataa ttatatatta
      841 gacgagaatg tttatatagg aaaaacagct ttaaagatta ttctatctaa tttgattagt
      901 aatgcggtaa aatatactga tgtaaatggg gtaattaata ttgggatagt taatgattgg
      961 ttatatatag agaattcata cggtaacaat aaaatttcga atatggataa aatatttgat
     1021 gttaaatttg atttaaataa ggaaaatagt aatggattag gtttatatat tgtaagtaat
     1081 attctgaata attacaatat agaatataaa gtattgcagg atgaagaatt ttttatcttt
     1141 aaaataaaaa tattttctta attaagatat aattttgcaa tagttattga aaaatagaga
     1201 cttatt
//
LOCUS       DACBYO010000233         1177 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.243, whole genome shotgun sequence.
ACCESSION   DACBYO010000233 DACBYO010000000
VERSION     DACBYO010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.243"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            98..391
                     /locus_tag="IVD26_003050"
     CDS             98..391
                     /locus_tag="IVD26_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080936.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            388..612
                     /locus_tag="IVD26_003051"
     CDS             388..612
                     /locus_tag="IVD26_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP6080937.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            609..>1177
                     /locus_tag="IVD26_003052"
     CDS             609..>1177
                     /locus_tag="IVD26_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP6080938.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLA"
BASE COUNT          406 a          180 c          248 g          343 t
ORIGIN      
        1 ttgtgcatta ctgaagaaga agcagataaa atcattagca aagaagagag cgcatcttaa
       61 ttgatgtgct ttttattttg attcaaggag ttgtcacatg attaatttag gggaatgggg
      121 agcgatagca ggatcaataa ccgctatcgt ttctttgatt ttattagtaa taaaaccaat
      181 tactgcatct ttctcgaaga ttactgagac tctttcaaaa gtaagtcaca atttagattt
      241 gctgactaaa gatttagaat cgagcaaatc agatcgattg atgattcatg aagaactaaa
      301 gaaacacgat gaaagattag atacacatac agaaaaattg gtggaacaca cgcaacaaat
      361 taaaacttta tttagggaga gaagaaaatg aataataaaa cgttcgaagt actaaaatgg
      421 ttcgcactgg taattattcc cgcactagct actttcgtgg ggttagttgg taaagcgctc
      481 aattggcagt acacagatat ctgtgttgtc atcattactg gttttggcgc gtttttaggg
      541 agtgtgttgg gtgtatcaaa tcgaacctac aaaatgttct cggctgaaag cgaagaagga
      601 ggaaacaaat gaaaaagaaa attactatta ctgcgatgag cctgttaacg gctctttttt
      661 tattacccat taatacgttt gcttatacta ttaatgacga gtataattta gcgccgaatc
      721 aaggagactc cagattagca attcctaaca aaattatttt gcacgaaact ggaatagatg
      781 caccagcaag aaacgtagcc gccaacatga aaaataatta taacggaagc aattcttata
      841 ctacagatgt tattggtgac ggtgggattg tttaccgtgt gggtgagcaa ggatatgttt
      901 cgtggggagc tggtaacgct aatccttatg cgcctgtaca gattgaatta cagcgcacat
      961 atgataaagc attgtttgaa aaaaactatc gagcttatat tgaatataca agagatagtg
     1021 caaaaaaata tggaattcca ttgactcttg atcaaggaac ttctttattt acaaaaggaa
     1081 tcatttctca tttgtgggtg acaaattatg tttgggggaa ccacacagat ccatatggtt
     1141 acttatcgca aatgggagtt agcaaagaaa agcttgc
//
LOCUS       DACBYO010000234         1172 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.244, whole genome shotgun sequence.
ACCESSION   DACBYO010000234 DACBYO010000000
VERSION     DACBYO010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1172
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.244"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..156
                     /locus_tag="IVD26_003053"
     CDS             <1..156
                     /locus_tag="IVD26_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HAP6080939.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
     gene            175..>1172
                     /locus_tag="IVD26_003054"
     CDS             175..>1172
                     /locus_tag="IVD26_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP6080940.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIM"
BASE COUNT          498 a           95 c          205 g          374 t
ORIGIN      
        1 gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat
       61 tcagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt
      121 ccagtggatg caattagtta tggagtaaga aaatagagag gagtagttag gaaagtgata
      181 aaaaatgcta tagcatatat tacaagaaag aaaaatagaa ctttaataat ttttatcata
      241 ttaactatag ttctttcttg cttgtattct tgtttaacaa taatgaaatc aagcaatgaa
      301 atagaaaagg ctttatatga aagttctaat tcttcaatat caataacaaa aaaagatggt
      361 aaatatttta atgttaatca atttaaagat attgaaaaat taaaagaaat tgaagaaaaa
      421 ataattcaat atgatggatt agcaaaacta aaagatgcta aagtagttag cggagaacaa
      481 agaataaata gagaagattt atctgacgaa tttaagaatg ttgtttcact cgaagctaca
      541 aataatacta aaagaaatat tttatttagt agtggagtat ttacaattaa agaaggtaaa
      601 aatatagaag aaaatgataa gaattcaatt attgttcatg aagaatttgc taaacaaaac
      661 aatctaaaat taggtgatga agttgatctt gaattactag atattgaaaa aagtggaaaa
      721 ataaaaagtc ataaatttaa aattataggg atcttttctg gtaaaaaaca ggaaacatat
      781 acaggattat cttctgattt tagtgaaaat atggtgtttg tagattattc aacaagccaa
      841 gagatattaa ataattcaga aaataatgaa attgcaaata aaattttaat gtattctggt
      901 agtgcagaat ctacagactt agccttaaac aaattgaaag agcttaaaat tgatgagtca
      961 aagtattttg ttgaaaaaga ttctaatgcg tttgaagagt ctttagagtc agtgagtgga
     1021 ataaaatata taataaaagt aatgacttat tctattatgt taggtgggat ggttgttctt
     1081 tcattaatct tgattctatg gttaagggaa agaatttatg aaataggtat attcttatct
     1141 attggaacat ctaagataca aattataatg ca
//
LOCUS       DACBYO010000235         1146 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.246, whole genome shotgun sequence.
ACCESSION   DACBYO010000235 DACBYO010000000
VERSION     DACBYO010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.246"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..1061)
                     /locus_tag="IVD26_003055"
     CDS             complement(<1..1061)
                     /locus_tag="IVD26_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6080941.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITE"
BASE COUNT          303 a          255 c          182 g          406 t
ORIGIN      
        1 tcttcggtta ttctttcttc ccaggatttt ggtcttaagg cctcattcag attgataaac
       61 agctttttta ctcgtttctg atactccttc atgacctttt tcattaatgt tttgattcta
      121 cgactataga ttccatagcg acgaatcgtt ttgaaattct tattttgaat atggcgaatc
      181 agtgcagcta tgaattcgtc tatactcatg gtcatcgtct ctttagtatt cgttcgtttg
      241 tccatgtagt tgaacatgac agtgtcgcca tcatacatta agattcggct taatgcgatc
      301 gggccacgct tcatataacg actgatgtat tggagtagtg actttagatt tgtcctgctc
      361 cttttaggag catttacgta aaacccttct ccattgttct tgtacgcagc ttgtaatctt
      421 gattgaactc tttgcttgtc ccactcacct aacgttcgtc taattagttt caatacagca
      481 tttttccagt attttcttaa catagaaaaa ggtaaataat cgtattcttc ccaacttcca
      541 tctcttgtta agccacccat agtaacaacc atatgaacat gcggattaaa ttctagtttt
      601 gatccaaagg tgtggattgt agctactata cctgccttca cctttctttt ctcaaaatag
      661 gcaagaataa tttttgcggc ttcatccatt agtcctttca gtaaggaatc tcgatagttt
      721 tccatcataa agatttcccg taacccctca tcgatcgtaa agattacgtg ccgatgtgtc
      781 actttaaaca tatcattcgc cacaaccgct gaccaccttt ggctttcacc tgttgcacac
      841 gttggacaga actttccacg acatttcaag ggaacaaact ttgtttgatg acatccctcg
      901 cagacaaaca gtcggtatcc tttttgaata tctccacaat atctaaactt gtttacttcc
      961 cgtttgacga ctagccgaat ctttcgcccg tatttctcaa caaagttatc ccaattatgg
     1021 tgttcgtcaa aaaagattgc ttcgagaata ttcgctttca tagtaatatt ttacttgttc
     1081 aaaaacaaaa tgaaaagggc taaaagactg gtagtgcagc ctttttagcc cttaactttt
     1141 tatact
//
LOCUS       DACBYO010000236         1127 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.247, whole genome shotgun sequence.
ACCESSION   DACBYO010000236 DACBYO010000000
VERSION     DACBYO010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.247"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..355
                     /locus_tag="IVD26_003056"
     CDS             <1..355
                     /locus_tag="IVD26_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080942.1"
                     /translation="GAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELL
                     RKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDT
                     EDSLRKGWGMNNKVR"
     gene            615..985
                     /locus_tag="IVD26_003057"
                     /pseudo
     CDS             615..985
                     /locus_tag="IVD26_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            985..>1127
                     /locus_tag="IVD26_003058"
     CDS             985..>1127
                     /locus_tag="IVD26_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP6080943.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTI"
BASE COUNT          430 a          134 c          233 g          330 t
ORIGIN      
        1 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
       61 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      121 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      181 taagcaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      241 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      301 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      361 aaagaagaac taagtaacta cctttaaacg gtagttactt agttcttctt tgatttgcat
      421 gaaatagagg ggatttattt ttctggttac gtgattaaaa aatccaaaaa atgagcatag
      481 gaacggttat gattttaggg tgtgttttaa tgagatattg tgatttcatt aacaagtgta
      541 tgataatctg ttgttgagtt agtaaataag taatagagct aactctaaaa taaaactatt
      601 aggaggagat gtaggtgaaa aagtttaaaa agaaaatata tttaggattg gttgttgggg
      661 tgagtatgtt tgggttcatg gctcatacta aacaagtaac tgcagatact aaccaaaaag
      721 aaaggattat gagccaatta gatgactctc aaataagtat gtacccaatg agctaattgt
      781 cagtttaaag gctacacaaa gaatttcaac agagaaaaat aaaccgcaaa atttattggg
      841 tgtaaaagtt atggtggaaa aagatttgac tcttaggaca aatgaaagcg attgtaataa
      901 gcgagatcaa gggttctgtt gcaaagtttt ccaaaaaatc tattttagtg taaaattgag
      961 aaaaaagaca gagaggacag agtaatgaat cattttaaag gcaaacaatt caaaaaagac
     1021 gtcattattg tcgctgttgg ttactacctg cgttacaatc taagctatcg tgaagttcag
     1081 gaattgttat atgatcgtgg aataaatgtt tgtcatacta cgattta
//
LOCUS       DACBYO010000237         1097 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.248, whole genome shotgun sequence.
ACCESSION   DACBYO010000237 DACBYO010000000
VERSION     DACBYO010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.248"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..1076
                     /locus_tag="IVD26_003059"
     CDS             <1..1076
                     /locus_tag="IVD26_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP6080944.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          384 a          216 c          198 g          299 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaat
//
LOCUS       DACBYO010000238         1064 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.249, whole genome shotgun sequence.
ACCESSION   DACBYO010000238 DACBYO010000000
VERSION     DACBYO010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.249"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            18..560
                     /locus_tag="IVD26_003060"
     CDS             18..560
                     /locus_tag="IVD26_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080945.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            650..>1064
                     /locus_tag="IVD26_003061"
     CDS             650..>1064
                     /locus_tag="IVD26_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAP6080946.1"
                     /translation="MDELKRTEIQIIDKKERPKNGFVLSEKTDLENTEAFNKESVKDL
                     RKLPTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIV
                     GVVTDPVDDNGENKEAIEKSKLIHEKTKASYPFLMP"
BASE COUNT          452 a          111 c          213 g          288 t
ORIGIN      
        1 cataaaaggt gtgtagaatg ttattgaaag tagctataaa atgctattgt gtaaaaaata
       61 aaggaggaat aatttatgaa aaaatagtac caagaggagc atgcctatta cttgcattat
      121 gtttgagctt aagcgcagtt gggtgtcaaa aaagtaatga aaacaataaa ataaaagaag
      181 gacaatccat aagttctgaa gaggaaggca tgtcaattaa tgcaaatggc aaaaatgaaa
      241 cttttaagcc atcagattat acattggagg caaagaaaga atatgtttat gaatatttag
      301 ggcttaaatt taaactctca gacaaattta gaaattatat agctgataaa aagatagcga
      361 tgttagatga tcaaagtcct atagataaag aactaaagta tgctattttg acatttgaga
      421 aaatgacaga agaacaaaag aatgcagtta tagaaaagat gggcgatgga tataaaaatt
      481 ggcaaaatga gcttgaaaga attgggacta ttggtatatt tgaaaaaaat acatcagaag
      541 aaaaaaatct aaaattataa aatgtgatac tcatactaaa ataggagttt caagtgatgg
      601 aaaatacgat tgctatttaa gcacaaatag cggagctgaa agtaatcttc tggatgaatt
      661 aaaaagaact gagattcaaa ttatagataa aaaagaacgt cctaaaaatg gttttgtgct
      721 atcagaaaaa actgatttag aaaatacaga agcatttaac aaagaatcgg ttaaagattt
      781 acgtaaacta ccaacaaagg acataaatgg caaggatttt acaagtaaag attttgagaa
      841 gtatgatctt actatggtaa atgtatttgc aacttggtgt acagcttgtg taaaggaaat
      901 tcctgatttg gttgaggttc agaatgaaat gaaaagcaag ggtgtaaata tcgttggagt
      961 tgttacagat cctgttgatg ataacggtga aaacaaggaa gcaattgaaa agtcaaagtt
     1021 aatacatgaa aagacaaagg cttcatatcc tttcttaatg ccag
//
LOCUS       DACBYO010000239         1030 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.250, whole genome shotgun sequence.
ACCESSION   DACBYO010000239 DACBYO010000000
VERSION     DACBYO010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1030
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.250"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..970
                     /locus_tag="IVD26_003062"
     CDS             <1..970
                     /locus_tag="IVD26_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAP6080947.1"
                     /translation="TSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVNDLD
                     THYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFIPW
                     ILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHIYD
                     NPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDLSS
                     VSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSCCN
                     VDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          368 a          129 c          179 g          354 t
ORIGIN      
        1 tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg attatgaaat
       61 atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt ttcgaaaggt
      121 aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag ctgactaccc
      181 tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa atttttctgg
      241 gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt ttgaatttat
      301 tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt taaaaaatat
      361 caatttagca aatataaatt atagtgatga acttccttta tcccctttac attggctatt
      421 agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc atatatatga
      481 taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat ttaatttaaa
      541 caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc aaataagttt
      601 gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat cctcagtatc
      661 tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt cagagtcaga
      721 aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag gtttgtgtga
      781 tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg ttgacaaagg
      841 aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata tgaataaaga
      901 agacttagat agtcataagt taattagtta tccaattata gaaaaacaac aaattaaata
      961 tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac aaaaaggcaa
     1021 agatattttc
//
LOCUS       DACBYO010000240         1006 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.252, whole genome shotgun sequence.
ACCESSION   DACBYO010000240 DACBYO010000000
VERSION     DACBYO010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.252"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            2..>1006
                     /locus_tag="IVD26_003063"
     rRNA            2..>1006
                     /locus_tag="IVD26_003063"
                     /product="23S ribosomal RNA"
BASE COUNT          311 a          201 c          289 g          205 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg taatagctca ctagtcgagt gaccct
//
LOCUS       DACBYO010000241         1002 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.253, whole genome shotgun sequence.
ACCESSION   DACBYO010000241 DACBYO010000000
VERSION     DACBYO010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.253"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            370..1002
                     /locus_tag="IVD26_003064"
                     /pseudo
     CDS             370..1002
                     /locus_tag="IVD26_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          182 c          184 g          294 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccgctac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta cc
//
LOCUS       DACBYO010000242          976 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.255, whole genome shotgun sequence.
ACCESSION   DACBYO010000242 DACBYO010000000
VERSION     DACBYO010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..976
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.255"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..702)
                     /locus_tag="IVD26_003065"
     CDS             complement(<1..702)
                     /locus_tag="IVD26_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HAP6080948.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFG"
BASE COUNT          329 a          161 c           83 g          403 t
ORIGIN      
        1 tccaaaattt gttcctattt cttcttcact atcttcaagt aagtatataa aatcacaata
       61 ttcatctata attccagaat ctccaaaatc aattattcca gttaatctat tattgccatc
      121 taacaataga tgattacaac taaaatcatt atggcataaa cactttttac cctcaaaaac
      181 tgttgttgca tttagtcttt ccataaaact ttctatataa tctttttcta tatcagttaa
      241 atcattataa atagtttcac gcaacaatat atactcttct aatacatttt gtttattatc
      301 aatagtacat tcactaatat ctgtataatc taaaccgtgc atttgtctta aaaaactggc
      361 aatatctcgt tttaacaaat tttgttcttc ttctgacata gtagaataaa tttctggtgt
      421 taaaaaagtt cctttaattt ctttataacc tagtatagat aattcatcac taatatacga
      481 atattcaata ttaggaattt ttacattagt ttctaaattt gtatttaaaa aattatatat
      541 tgctttttct tttgcataac cttttttctt attagtacta aattttgttt taaaaatgta
      601 ttcattatta actaaatatg ccacactatc ataaccacta ccgattattt caatactatc
      661 tactttgaaa ttatcaaagt aatgctcaat taaatatttc attgccttaa catttgtggc
      721 attatcatca tatctatatt ccattaaata acaatcttct tttttgccct cgtgtaattc
      781 atgttctggc aaatcttcaa taattctaaa accagatttt tggtatgccc ttattgctct
      841 tggattattt ttatgagggt ctaaaataac tgcattagca tttctttctt ttttcaaaaa
      901 ttcaaaaatc aatttaatat atcttgtacg gttctgttgc aaagttttaa ataaagaata
      961 aaatccctta cggtat
//
LOCUS       DACBYO010000243          954 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.256, whole genome shotgun sequence.
ACCESSION   DACBYO010000243 DACBYO010000000
VERSION     DACBYO010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.256"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..332)
                     /locus_tag="IVD26_003066"
     CDS             complement(<1..332)
                     /locus_tag="IVD26_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAP6080949.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLP"
     gene            complement(434..787)
                     /gene="tnpB"
                     /locus_tag="IVD26_003067"
     CDS             complement(434..787)
                     /gene="tnpB"
                     /locus_tag="IVD26_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAP6080950.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          267 a          191 c          172 g          324 t
ORIGIN      
        1 ggaaggagat gttctttctc tgttataggt aagtgtttga ttttgtctgc tttcgttcct
       61 acaactcgtt gatgtccttt tactggaata atggtggcag ctgcttctgg aacacttaca
      121 gaaatttctt catcactaaa aagattcaat tgcccattcg tttcctcaaa gagagtctct
      181 ttagagcgtc caaataattt gttggttaaa taattgacct tttcattcaa tagttggatt
      241 tcagttgtaa gattctgaat ggtttgttgt tgtgcttgat tggttttatg ggcttcttga
      301 agcaactgaa gcaacgtatc tgtagtttcc aaaatttttc accaccttga atcgaactga
      361 ttttgttaca gaataccaca agaaacgcac aagaaatagg ggttcaacac attttttgtg
      421 ttaacccccc agcttaaaaa actccttttt ttcctggcaa aatagctcga ggttgatcga
      481 tacttaatcc ttctaacaac catcgaacct gttggttcgt taaggttcga acttcgtctt
      541 tcgtccgagg ccattttaac ttgccgtttt ctatccgctt ataacagaga agaaaaccat
      601 caccgtccca atagagaagt ttgaaacggt cttgacggtt cccgcaaaat aaaaaaacgg
      661 catcttcgta aagctcgagt tgatactctt gttgaataag actggcaaga ccatcaattc
      721 cttttcgcaa atctgttttt ccgcacacaa tataaatatg tttggtttga agtaaatcat
      781 aaagcattgg acaacagttc tttcaaaata gcttgaagaa tataattgtt aataccgtta
      841 tagatcaaaa cttcagaacc attctctctt ttgatgcgca tcgctaactt ggcagccgcg
      901 ggtttacctt tttctggtgc actcttttcg tttcctaatt ggacaggaac aatc
//
LOCUS       DACBYO010000244          950 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.257, whole genome shotgun sequence.
ACCESSION   DACBYO010000244 DACBYO010000000
VERSION     DACBYO010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.257"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..747)
                     /locus_tag="IVD26_003068"
     CDS             complement(<1..747)
                     /locus_tag="IVD26_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6080951.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQ"
BASE COUNT          354 a          177 c          125 g          294 t
ORIGIN      
        1 ttgatcgaat accgtataaa atgtccatgt aaaaacaata aagatgatta tcgtccataa
       61 ttgaggcagt ttcattagat caaacatttc ttttaaagaa ggaatactat ttgattcagc
      121 ttgttcttga ttaaaatttt gatttgcttc ccgttcaact ttagggttcc aaaataataa
      181 atttaacaat agtaaagaac caaagaaaga tcccgcccaa aagtttaaat gaggattttt
      241 tacaaataaa aatcctgcca aaagcgctac caaggcataa ccaaatgatc cccacgccct
      301 tgcttgtcca tattcaaagc caaataaacg actaaacctt tctgacacag cttcaaaaac
      361 tcctacagaa gctaaatatc cagctgacaa aaatagcgct cccataataa tgcctaaatt
      421 aaaattgtta tctagcaatg gcccatatat ccatataaaa aatggtccaa caagtgtcgc
      481 taatacagaa gcaaaaatta ataaatttcg tttaatatac aatttatctt gtaatgttcc
      541 ataaataaac atcaaaatta aggtaactaa cgaatttgcc gagaatactg ttcctacagc
      601 actgccagat aaccctaaac catttgattc agatgttagc caaagttgaa aaaatgacca
      661 ccaaacaccc caagaagcaa aaaatagtaa taatgtagct gaactttgta aataagattg
      721 atttttaaat acgttaactt ttgacatatt tttatcctcc aacgatatat ttgtatcccc
      781 tttcatgata accggttaac atttttagaa aaggacttgt actcctaaaa ttataaaaga
      841 aatccgctta catgtcaacc ggttattcta tttggataat gccatataat gtcacaggat
      901 atgactttta ttggtgtgtc gcttttcttt tttaatggca ctatttttta
//
LOCUS       DACBYO010000245          890 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.258, whole genome shotgun sequence.
ACCESSION   DACBYO010000245 DACBYO010000000
VERSION     DACBYO010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.258"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..888
                     /locus_tag="IVD26_003069"
     CDS             <1..888
                     /locus_tag="IVD26_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAP6080952.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          244 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt
//
LOCUS       DACBYO010000246          859 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.260, whole genome shotgun sequence.
ACCESSION   DACBYO010000246 DACBYO010000000
VERSION     DACBYO010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.260"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..>859)
                     /locus_tag="IVD26_003070"
     rRNA            complement(<1..>859)
                     /locus_tag="IVD26_003070"
                     /product="16S ribosomal RNA"
BASE COUNT          186 a          264 c          191 g          218 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtc
//
LOCUS       DACBYO010000247          847 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.261, whole genome shotgun sequence.
ACCESSION   DACBYO010000247 DACBYO010000000
VERSION     DACBYO010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.261"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..598
                     /locus_tag="IVD26_003071"
     CDS             <1..598
                     /locus_tag="IVD26_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP6080953.1"
                     /translation="MKKEFPIPISWTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVG
                     GGALQEGRFIEGFSHPEMGHMLVVPHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKK
                     GQEVAEDDPYWEIEASYIAQCAYNTTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLV
                     NGYVETPELSKYIVTPALEDNAGTLGCLALAREAVLHS"
BASE COUNT          243 a          158 c          208 g          238 t
ORIGIN      
        1 catgaaaaaa gaatttccga tcccgatttc ttggacaaca gatgtcaatg cggctgccta
       61 tggtgagtat gtcttcggca gtggcaaagg attgagcagt gtcgtttact atacgatcgg
      121 tacgggtgtt ggcggcggtg ccttacaaga agggcgcttt atcgaagggt ttagtcatcc
      181 agaaatgggg catatgctcg tcgtccctca tccaaaagat gactttgctg gcagctgtcc
      241 atttcatggc aactgtttag aagggatggc cgctggaccc gccatcgaaa aacgcttagg
      301 gaaaaaagga caagaggttg cagaagatga tccttattgg gaaatcgaag cctcctatat
      361 tgctcaatgt gcctacaata caaccttgat gttttctcca gatgtgatca tttttggcgg
      421 tggtgtgatg aaacaacgcc atatgctgca aaacgtccac gacgcatttg caaaattggt
      481 caatgggtat gtcgaaacac ctgagttaag caaatatatc gtgaccccag cattagaaga
      541 caacgctgga acgctcggtt gtttggcatt ggctcgagaa gcggtcttac attcataaac
      601 gaaaaaaggc tcttcgacat ttagtgttgg tagagaaaga tacaactgaa aatttagtca
      661 taaccagtta ggcagagtgc ttaactggtt tttgttttac ttggaagatc aagccttgaa
      721 tgagataaat tcttgctcga aagttatgga aatttcgata gccgtaggcc acttgtattg
      781 tgcaatagtt ttttacaaaa aaaagggggt gcggatattt ttttggacct ttttaacaaa
      841 tatatct
//
LOCUS       DACBYO010000248          846 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.262, whole genome shotgun sequence.
ACCESSION   DACBYO010000248 DACBYO010000000
VERSION     DACBYO010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.262"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(37..237)
                     /locus_tag="IVD26_003072"
     CDS             complement(37..237)
                     /locus_tag="IVD26_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP6080954.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT          272 a          144 c          134 g          296 t
ORIGIN      
        1 ttttctttcg aaaagacggt taaaagtcaa tttttattaa gctttaacaa tgtttgttgc
       61 ttgagggcca cgttgaccat cttcaacatc gtaagacact gcttggcctt cttctaaagt
      121 tttgaagccg tcaccttgga tagctgaaaa atgtgcaaat acatcatttc catcttcacc
      181 agtgataaag ccaaaacctt tgtctgcgtt gaaccatttt actgtaccgt tattcataaa
      241 taaattcctc ctgatacgta tcaatgtacg ttttttcgtt gcaataaata tttgataggc
      301 aaaaggagtt ttatctatgt agatatatcg ctcaaattac gtttcaaaat agattactca
      361 tttaatatat catgcttttt ctaataacac aaggataatg caatgaaata taaaattcat
      421 tgtcttctat tgtcttcgaa tcgaagaaaa agttgaataa ccgcgattga ttcacttttt
      481 gttttcttgt ttatttgctt ttatctgcaa cttttgactt taaaatttct taactatgaa
      541 aacctttcaa ttggtggtat acttataaat ggaatttcgt tatcaacgcg ttcgttgcct
      601 ttcagcaagt atttaaagaa aggagaatgg ctatgacatt ctataacaaa gatatacaat
      661 atcgagtaac cttggataca gatttgaatc tatttgtcgt ttttgacaaa gaaaatacca
      721 atcatgtagc gacaggtgtt acgatcgaac aagcagtgca agaattaaaa aaatctgcat
      781 aaggagtgga aaccctcata tggacgattc tcgttcttct ctttaaacgc atctactggt
      841 agataa
//
LOCUS       DACBYO010000249          808 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.263, whole genome shotgun sequence.
ACCESSION   DACBYO010000249 DACBYO010000000
VERSION     DACBYO010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.263"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            74..697
                     /locus_tag="IVD26_003073"
     CDS             74..697
                     /locus_tag="IVD26_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP6080955.1"
                     /translation="MKIAYIRVSSIDQNEQRQIEEMKKFGAEKIFIEKQSGATITHRP
                     IFQEALEFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PHLDKFIKDLIIQILAMIAEQERTESKRRQAQVIKIAKANGVYKGRPKLYSADTKNPQ
                     RRLVYENIVKDLNEGIAISKIAKNYNITRQTIYRIKNDIEYNSNQMN"
BASE COUNT          302 a          130 c          135 g          241 t
ORIGIN      
        1 ctttatagtg tataaaaaaa ttagtgttga ttttgagtgt attttaaata gtttgaggaa
       61 gtaggtaaaa attttgaaaa ttgcttatat tcgagtttcg tcgattgatc aaaatgagca
      121 acgccaaatt gaagaaatga aaaagttcgg cgcagaaaaa attttcatcg agaaacaatc
      181 tggagcaacg attactcatc gaccgatttt ccaggaagct ttagagtttg tccgagacca
      241 agatattttt attgtcgaag caatcgaccg acttggaaga aattacgacg aaatcattgc
      301 ttcagtcaat tacctaaaga agaaaaacgt gcagctgatc atcaccagtc taccgatcat
      361 ggctgaagca attggcaatc ctcatttgga taaattcatt aaagatttaa tcatccaaat
      421 tttggccatg attgcagagc aagagcgtac cgaatctaaa cgacgccagg cgcaagtcat
      481 taaaattgca aaagcaaatg gcgtctataa aggtcgtcca aaactctata gtgcagatac
      541 aaaaaatcct caacgacgtt tagtttatga aaacatcgtt aaggatttaa atgagggcat
      601 agctatttca aaaattgcta aaaactacaa tattactaga caaactattt acagaattaa
      661 gaatgatatt gagtataaca gtaatcaaat gaattaaaaa agttctttat acattaaaat
      721 ttcttctttt aactcatcaa ttctaggaga tctaacatca gaatcagcaa ttgcatttaa
      781 taacttatca atattttctt tattcgct
//
LOCUS       DACBYO010000250          796 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.264, whole genome shotgun sequence.
ACCESSION   DACBYO010000250 DACBYO010000000
VERSION     DACBYO010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.264"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..>796
                     /locus_tag="IVD26_003074"
     CDS             <1..>796
                     /locus_tag="IVD26_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP6080956.1"
                     /translation="AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVM
                     TYMFSFEGIKGYGYVVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLL
                     TIGLFVSYVAHQYQVFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKEL
                     VYLKKYTDSLEKDQEKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYL
                     TNKFEYRYLKNIKNEYLKSLLIAKLYQANNNKICCKFECPSTIIEVP"
BASE COUNT          291 a           84 c          120 g          301 t
ORIGIN      
        1 cgcagctata cctataatcg gaagttattt tatattaaag gaaaagaaga aaactaatat
       61 agtgctttta aataaattac tattatgtat gcttattgat gatttcagat ctattattac
      121 ttccatggtt atgacgtata tgttttcatt tgaagggata aaagggtatg gttatgtagt
      181 attccagata atgcttgatt ctttgttttt gctgatgttt atttggttat atagaaaatt
      241 agctataaat aggattgttg aacagtccag ttctaaactt actgctatat tcatgattta
      301 tttacttaca attggtttat ttgtttctta tgttgctcat caatatcaag tatttgatca
      361 ttttgtgttt ggtgtcttaa tatttttaat cattcaaatg tttgttgttc tatttttatt
      421 tattagaata actattaggc aacgagaaca atatgaacag caattgaaaa gaaaagaatt
      481 ggtttatcta aaaaaatata ctgattcact ggaaaaagat caagaaaaat ttgccagatt
      541 tagacatgac tataaaaatt tattgctgag tttaaaagaa atcgctaatc aaaaccatga
      601 ttcgatattg gaaaaagaaa taaaagaatt agagatctat tctaattctt atctaaccaa
      661 taagtttgaa tatcgttatt taaaaaatat aaaaaatgaa tatttgaaaa gtttgttgat
      721 agcgaagcta taccaagcaa ataacaataa gatttgttgt aaattcgaat gtccaagtac
      781 tattattgaa gttcct
//
LOCUS       DACBYO010000251          786 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.265, whole genome shotgun sequence.
ACCESSION   DACBYO010000251 DACBYO010000000
VERSION     DACBYO010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.265"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..>786
                     /locus_tag="IVD26_003075"
     CDS             <1..>786
                     /locus_tag="IVD26_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HAP6080957.1"
                     /translation="NTDQLKQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDF
                     PSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQ
                     IAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNIL
                     GDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLG
                     CQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT          266 a          141 c          143 g          236 t
ORIGIN      
        1 aatactgatc aactgaagca acgcgataca gtgattattg cttgtgttat atggggcata
       61 attaatggct atactagcca aagagccacg tatagagcgg tttgttccgt cttatttcct
      121 aatggtgact ttcctagtag gagtcgattc actcgcttaa gttcaaactt agcttacact
      181 atcaagatta ttcgatactt tttcatcaag aagctcacca aaggtgaact agtcggaatt
      241 atagatagtt ttcctagtcc attatgtaaa ccagttagaa atagacaagc aaaactattg
      301 aatcaaatag ccaaagttgg ctataactca acaaaaaaat cttattttta tggtcttaaa
      361 attcatatga tcgttactaa gactggcttt ccgattactt actcaatcac gaatccaggt
      421 gtccatgacg tgaaagtgtt agagacttta tcggaagaag cgaatcttcc caatatccta
      481 ggggacaaag gatatattag ccataaaatc catgaaaagc ttgcccttaa gggcattact
      541 atatccgttc cgccacgtaa aaacatggat aaatcagaaa aactagacca cagcttactt
      601 ggaaaacaaa gaaaaacagt tgagactgtt ttttcttcct tagaaaaatt aggttgtcaa
      661 aatttcaact cacgttctgt taaagggcta gagagtagat ttgaaagcat attactggct
      721 tacagtgttc tattaagtcg agcacaacga cgttttgaag gaactttgag atattcttta
      781 ggatat
//
LOCUS       DACBYO010000252          785 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.266, whole genome shotgun sequence.
ACCESSION   DACBYO010000252 DACBYO010000000
VERSION     DACBYO010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..785
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.266"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            22..714
                     /locus_tag="IVD26_003076"
     CDS             22..714
                     /locus_tag="IVD26_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAP6080958.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT          282 a          151 c          158 g          194 t
ORIGIN      
        1 aaaaaaagga ttttagtaac aattggtcta gcttttttgt tagctggttg taccaacggg
       61 aatgaatcga aaaaagaatc aacaaaagaa acagcgaaag caacagttgc aactactaca
      121 acaactagca cagagagcaa gtcaactgca gcaagtacag aaacagcaga tacctctact
      181 tcgtcagagt cttccaaaac gactgaaaca actcaaacat ctacttcaag ttcttctgta
      241 gaggcttcat cttcctcttc agaaagcagc gaacaagttg aacaaacact gtggaatgca
      301 gacaaatccg cacaattaga ggcatttatg accaaatggg gccaaacaat gggacaacaa
      361 tacaaaagtt atacgaatca aatgagtgtg gacttatatg gtcttaaagt ccctcaagct
      421 attttgaacg gggagtggaa gatggctatt ggtggagtgc ctgtttctgc agaatggtca
      481 gaaagtggga caggtcaagc agactatcaa atcacagccg tctattccga tgcagagaca
      541 gaaccatatc tgaaaaagca cgtctatcta ttcgggtttc agcaaaatca gccaaaagta
      601 ttggtgacac aacaaaatca ggggaatccc gataattatc tttacttcaa cgagacagcg
      661 aataatgaat tgaaaaatgg ctttaatcaa atcgtttatg gacaagcaaa ttaatgagat
      721 aaacaagggg ttgtgacatg tcttttatca caaccccttg ctcagtttat ttgttagtct
      781 tttat
//
LOCUS       DACBYO010000253          772 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.267, whole genome shotgun sequence.
ACCESSION   DACBYO010000253 DACBYO010000000
VERSION     DACBYO010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.267"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            58..414
                     /locus_tag="IVD26_003077"
     CDS             58..414
                     /locus_tag="IVD26_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP6080959.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
     gene            404..670
                     /locus_tag="IVD26_003078"
     CDS             404..670
                     /locus_tag="IVD26_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6080960.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
BASE COUNT          305 a          103 c          158 g          206 t
ORIGIN      
        1 attcgaattt ttatgttata tactataata taaaatcaat atatgatata attgggtatg
       61 gaaaaaatat cttttgaaac atttaaaaga cctaatggtc atgatgaatt tttagaatgg
      121 ttggaaacat taccaaaaaa agatagtgcg aagcttttac gtacaataga agaaacagaa
      181 aagaatggga tgctagtagc tcaacggttg aaatgggtga aaaaattaga cactaatttg
      241 tacgaattaa gaagtaaggt aggatcaaac atccaaagag ctatctattt ccatgtggtc
      301 aatggaaggt atgtcattac ccatggattt actaaaaaaa cggagaaaac accaataagt
      361 gaacttaaac atgcaaaaga acttagagag gagtggttca caaatgatga ttaaaaaatt
      421 gattgaagaa aagcaaaaag acaaagattt tgcagaagca tatgaccgtg aaggaagaaa
      481 actcgaaact gcggttgctc tttatcatgc acgggaggaa gcaggcctaa ctcaagcgga
      541 gcttgcacaa aaagcacata caactcaatc tactattgct cgaattgaga gaggggataa
      601 cgtatctttc gataaacttg atgatatcgc tagggcatta ggcaaaaagc tggtagtaga
      661 atttgcttaa aagcgagttg aaaatatacc tgtaataggc tcctaactaa tcaattagtt
      721 tagtgggcct ttttgtacta aatagataaa agttgtccta tagtgtaaaa gt
//
LOCUS       DACBYO010000254          767 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.268, whole genome shotgun sequence.
ACCESSION   DACBYO010000254 DACBYO010000000
VERSION     DACBYO010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.268"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..104
                     /locus_tag="IVD26_003079"
     CDS             <1..104
                     /locus_tag="IVD26_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP6080961.1"
                     /translation="LESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
     gene            160..657
                     /locus_tag="IVD26_003080"
     CDS             160..657
                     /locus_tag="IVD26_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP6080962.1"
                     /translation="MNNQIALAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT          261 a          113 c          148 g          245 t
ORIGIN      
        1 ggctagagag tagatttgaa agcatattac tggcttacag tgttctatta agtcgagcac
       61 aacgacgttt tgaaggaact ttgagatatt ctttaggata ttaaaattaa ctagcaccac
      121 gggtgattta tagtatacta tgtcaaaagg aggagttaga tgaacaatca aatcgcacta
      181 gcgtatttag attatgatga tctagatgct ttacaagttg taagtgttgt cagtttttat
      241 gaatcgttta tcgatggcgc agatccactt gatatgcaag gatatttaca gacacaattg
      301 acaactgaaa tattggcagt agaattggca cagtcaacca gtaaatttat tggtattaag
      361 gatcatcaaa tactcattgg ttatatgaaa gtcaatgatg aaaaagatgc tatagagatt
      421 caacggctct atctgctcaa agattatcaa aacaaagggt tagggcaacg gttactcgat
      481 gaagcgaatc gttatgctaa aacgaaacaa aaacgttatt tacgtttgac tgtttatgaa
      541 aaaaatcatg caggtattcg tttttatgaa cgtcatggat ttaaaaaaat cgggatcaaa
      601 cattttcctt taggaaaaca agatcgtatt tgtccgattt tagaaaaaga aatctaaaaa
      661 aacgtcctca cttttgatgc tgaggacgtt tttttagact ggtaatggaa ccataattcg
      721 ctttcttttt tgataaatcg ctaattccgt cacacctttt gctttta
//
LOCUS       DACBYO010000255          761 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.269, whole genome shotgun sequence.
ACCESSION   DACBYO010000255 DACBYO010000000
VERSION     DACBYO010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.269"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            132..>761
                     /locus_tag="IVD26_003081"
     CDS             132..>761
                     /locus_tag="IVD26_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080963.1"
                     /translation="MNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAFHINR
                     ALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLYIVTL
                     ITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPLILLG
                     FIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKK"
BASE COUNT          258 a           96 c           99 g          308 t
ORIGIN      
        1 aaacactact tttgtaatat aaaaaatatt ttattaataa taaaattaat cacattttat
       61 atagtgacta atctagtgtt taaaaaaaat aaatgatact atatgtaata taaaaaaaca
      121 tgaggtggta tatgaatttg aaaaaaattt tttctgtaaa aatatttata gtttatgcat
      181 ttgttagttt attatattta tttccagcat ttaaaaacat ggaaatattt ggcttttatg
      241 atacggcatt tcacattaat cgtgcgttaa gtttagaatc tatttttagc tcccctatta
      301 attttgaaac gtttagatca tatggcatgc aagtaaataa tttttaccca tggttaactc
      361 tatatccttt atttttattg atcaagttta ctaatttagc aataggctat aacctttttc
      421 tttatattgt tacgctcatt actctattta tatgtcatta tgtaatgtat gaaattacca
      481 aaaaacatgt tactagctcc tttttcgcta ttatatatac aacatcttct tttaggagtg
      541 tagaaatatt tcttcgaggg gcaatggggg aattactcgc aatgtcaata cttcctctta
      601 ttttactcgg gtttataaag ctttacgact caaaaaaaga atcttgggtt atgttggcga
      661 ttagcatgac tttattaatt tacactcatg ttctttctgt agctatgact atggtaatga
      721 ttataattgc tttaattatt caattttatc ggaaaaagaa a
//
LOCUS       DACBYO010000256          737 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.270, whole genome shotgun sequence.
ACCESSION   DACBYO010000256 DACBYO010000000
VERSION     DACBYO010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..737
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.270"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            1..737
                     /locus_tag="IVD26_003082"
                     /pseudo
     CDS             1..737
                     /locus_tag="IVD26_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT          249 a          140 c          140 g          208 t
ORIGIN      
        1 cttagaggag accgtcattc acctcttccg aaaaggtatt accatgtcgg aaatcgcaga
       61 cttgattgag aaaatgtatg ggcatcacta cacgccccaa accatgtcca acatgactaa
      121 agtgctgact gaagaagtaa atgcatttaa agttagaact ctaaatgata agtatgtcgc
      181 tattttcatg gatgctactt atattccttt aaaacggcaa accgtctcca aagaagcaat
      241 ctatattgcc attggtatac gagaagacgg cactaaagaa gtactaagtt atgcgattgc
      301 tccgactgaa tcgacctacg tttggaatga gttgttacag gacatttact ccagaggggt
      361 tcatgatgtc ttactgttta ttaccgatgg cttaaaaggc atgaaagata cgattcacca
      421 gatttatcct aaagctaaat accaacattg ctgtgttcac gtttcccgta atattgctca
      481 taaagtacgt gtcaaagatc gaaaagaaat ctgtgatgat tttaaggctg tttatcaagc
      541 tagctcaaag gaagaggcaa ataccttttt agggagtatg attgagaagt agcaaaaaac
      601 ttatcctaaa gtgacgcagt cactgataaa aaatcaagat ttattgactt tttatgagtt
      661 tccgcctggt atccgccgaa gcatttactc aactaattta atcgaatctt tcaagaaaca
      721 aatcaagaaa tacagcc
//
LOCUS       DACBYO010000257          695 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.271, whole genome shotgun sequence.
ACCESSION   DACBYO010000257 DACBYO010000000
VERSION     DACBYO010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.271"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..461)
                     /locus_tag="IVD26_003083"
     CDS             complement(<1..461)
                     /locus_tag="IVD26_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP6080964.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYS"
BASE COUNT          221 a          127 c           99 g          248 t
ORIGIN      
        1 ttactatata cagaaataga aggtgggaca tctaaataga tgacgtcaaa ctcatcaaat
       61 aatggttcta gcttttcttt catatatttg aattgggata atgaatcatt atattggtct
      121 ttgatccaat catcatacat ttcaaaggac atgtctgctg gaagtatata gaggttattg
      181 attactttat agacagcctc tttaggtgga agattgttta tcaacacgtc agtcacagta
      241 ttttcgtaaa caatcggttc accttctccg cctccttctt cgttagtgaa gttcatatgc
      301 gttaagttca tcacatcaga agtatttcct tgcatatcca agtcaattat caaggttctt
      361 tttccttcat taactgctga ttcaaaccct aacatttgcg cgcacgtact tttacctacg
      421 ccacctttaa aattaccgat tacatatttc ttcgctacca cgttcctacc tcttttcttt
      481 tagcaatatt catttgatac tattataaca tatttatttt tagttactac caaaaaaaga
      541 tatatatgta ctaccttata attaataagt aaaaggtagt acataaataa ggaaaagctg
      601 aaatatattg atttatagct ttcctcaaag taatgacgtt atttaattta tcgagaagca
      661 gagaatactc gcgactttag tcatgtagac gaatc
//
LOCUS       DACBYO010000258          688 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.272, whole genome shotgun sequence.
ACCESSION   DACBYO010000258 DACBYO010000000
VERSION     DACBYO010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.272"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            124..327
                     /locus_tag="IVD26_003084"
     CDS             124..327
                     /locus_tag="IVD26_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAP6080965.1"
                     /translation="MKHCVILGILGTCLAGIGTGIDVDAATYYGNGLYCNKEKCWVNW
                     GQSWSEGLKRWGDNLFGSFSGGR"
     gene            327..677
                     /locus_tag="IVD26_003085"
     CDS             327..677
                     /locus_tag="IVD26_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP6080966.1"
                     /translation="MTSINIDHTKKVIHELYNSLMTRPNQTKALLDITDVLFQVYKKI
                     DTAKYPEILVNKLVNYIYIVGFDNKIRFIDNDEKLLIELGDISKKAGINSKYKANFTD
                     KSQFYSYSETMPQR"
BASE COUNT          287 a           69 c          115 g          217 t
ORIGIN      
        1 tcaatcattg ttatataata aaatgttata taataaaatt actaatgata tttaatatta
       61 caagcaatct taagaaattc gaaaaggaaa aaatgattat gaaaaagaaa gaaaaagaaa
      121 gtattgaaac attgtgttat tctaggaata ttaggaactt gtctagctgg cattggtaca
      181 ggaatagacg ttgacgcagc tacttactat ggaaatggtc tttattgtaa caaagaaaaa
      241 tgttgggtaa attggggaca atcatggtca gaagggttaa aacgttgggg agataatctt
      301 tttggtagtt ttagtggagg acgataatga cttcaataaa cattgatcac acaaaaaaag
      361 tcatacatga attatacaat agtttaatga cacgacctaa tcagacgaaa gcattattag
      421 atattactga tgttttattt caggtatata aaaaaattga tacagcaaaa tatcctgaaa
      481 ttcttgtaaa taaattagtt aattatattt acatcgtggg ttttgataat aaaatacgct
      541 ttattgataa tgatgaaaaa ttattaatag aattagggga tatttctaaa aaagctggaa
      601 ttaatagtaa atacaaagca aactttacag ataaatcgca attttatagt tattcagaaa
      661 caatgcctca acgataaaat atagtata
//
LOCUS       DACBYO010000259          686 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.273, whole genome shotgun sequence.
ACCESSION   DACBYO010000259 DACBYO010000000
VERSION     DACBYO010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..686
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.273"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(82..339)
                     /locus_tag="IVD26_003086"
     CDS             complement(82..339)
                     /locus_tag="IVD26_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP6080967.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(332..601)
                     /locus_tag="IVD26_003087"
     CDS             complement(332..601)
                     /locus_tag="IVD26_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP6080968.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
BASE COUNT          213 a          130 c           83 g          260 t
ORIGIN      
        1 attgctaaga aacgtaatgt aatgaaaaaa atagaggtca aaaacttaaa agtttctgac
       61 ccttccctta cttccaattg gttaatagtg atcttttgca gaataaataa atatcgtttc
      121 attttcaact ctatatatca gtctatgttc atctgtaatt cttctggacc actttccaga
      181 taaatcatgc tttaatggct caggttttcc taatccagca aagggagaac gatcgatatc
      241 ttttattaac ttgttaatct tttttatatt gcttttgttt ccttgctcat gccaataaag
      301 ataatcatcc caagcatcat cagaccaagc cttaatcatc agattcaacc tcgattaagt
      361 catgtgtttt aaatgcacct ttggagaatt gttcatctcc tcgacgaatt ttttccatga
      421 cgtaattatt agaaagtgtt ctcaacgttt cttgcataga atcataatct ctttttgata
      481 atacaacaac tgtatcttct acatctttac ttgttacaat aagtgtttca gcatcctcat
      541 taacttgttt catataacta cgtaaatttt ggcggaaatt tgaataagct actgcttcca
      601 ttcctttcac cccttattta tttctataaa acaattgtac attatattgt acaattaagc
      661 aaatgattaa tattctaact tcttat
//
LOCUS       DACBYO010000260          683 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.274, whole genome shotgun sequence.
ACCESSION   DACBYO010000260 DACBYO010000000
VERSION     DACBYO010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.274"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
BASE COUNT          259 a           78 c          133 g          213 t
ORIGIN      
        1 tgtgattaac aagttacttt tcattacatc gaatttttca gaagttgctt atattggtga
       61 tgatattaat gatttatcat gtatgacatc tgtgaagaag cgggaggaat agtagaatgt
      121 ccaaaaaatg ccacaagaaa tgagattgaa ttatctgatt ttattgtaac tcacagtggt
      181 ggtgacgaat ctgtgataga gtttattgag tggatattgg aatcgatata gtgtagtagt
      241 acagaaaaat tatcatacaa ttaatactag gcataagaat attggcatat tctagagtta
      301 aaagtaacta ttcgaaaagg ataaggttag aattttttgt tttgccagtg gaagaatata
      361 aaaagggcat tggaaattaa tatattagaa tgctaagcgg agaaaaaaat atatgaaaag
      421 tacgtccttg tgatgggatg gaaaaataca cttatttcaa acaacgataa tataattatg
      481 tgaaccgaag tatactcgct tctaattcaa tcctcaaatc ccgacagtcg cgacttcaaa
      541 aaagcgtata gttttaatgt atccccatat gatccgaaaa atggtaattt acaattaaca
      601 gtttgatgat gttgaagatg tggaaatgct gaaattacca tgatgagaaa cacattaatt
      661 aaagggaatt aattaactag aat
//
LOCUS       DACBYO010000261          661 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.275, whole genome shotgun sequence.
ACCESSION   DACBYO010000261 DACBYO010000000
VERSION     DACBYO010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.275"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            23..646
                     /locus_tag="IVD26_003088"
     CDS             23..646
                     /locus_tag="IVD26_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080969.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
BASE COUNT          229 a          104 c          144 g          184 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 g
//
LOCUS       DACBYO010000262          640 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.276, whole genome shotgun sequence.
ACCESSION   DACBYO010000262 DACBYO010000000
VERSION     DACBYO010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.276"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(150..>640)
                     /locus_tag="IVD26_003089"
     CDS             complement(150..>640)
                     /locus_tag="IVD26_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAP6080970.1"
                     /translation="FRAIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQ
                     MYEQNQQDYLNFKIGMFAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQT
                     SKLANIHIIDPSMNKWFDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNI
                     DE"
BASE COUNT          218 a          104 c           77 g          241 t
ORIGIN      
        1 ctataattcc accccaagca aaagctattt tcatcgggat attagttaca ttaaaagtac
       61 taggcataaa ataaagcaga caaatgatta aatttattac tcgaaacgca tctcgactta
      121 ataaactctt ctctaaaaca ggtactattc tattcatcta tatttccaac tttcaaaatt
      181 tctttatcaa ttctatttaa tagtttatca gagtaatccg atttaacttt tcttacaaat
      241 aatttttcac tttcttttat ttgatctata tccctttcat caaaccattt gttcatggaa
      301 ggatcaataa tatgaatatt tgctaatttc gaagtttgta aagtagtttc ttcaatattt
      361 ttcaattcaa gtggtaaatc tggtcctcca ataacatttt tatttttgaa cgaggaatta
      421 aaaaaaagtg tatgaaaaaa tttttcatct ggggcaaaca tacctatttt aaaattcagg
      481 tagtcttgtt gattttgttc atacatttgt attaattctg ttaggcattc tttcgacaaa
      541 gcccaccatt gagaaccatg atacaaatca aatttatggt gtctaatttt tgggggaagt
      601 ttaatcatcc tcagacaacg attaattata gctctaaaaa
//
LOCUS       DACBYO010000263          633 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.277, whole genome shotgun sequence.
ACCESSION   DACBYO010000263 DACBYO010000000
VERSION     DACBYO010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.277"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            145..576
                     /locus_tag="IVD26_003090"
     CDS             145..576
                     /locus_tag="IVD26_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080971.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
BASE COUNT          247 a           93 c          128 g          165 t
ORIGIN      
        1 tggttgggtc aatagaccgt tctactttga acagtgctca actatctatt ggcgcagacg
       61 gagccattaa atggagaaga aattcaagtt atggatcagc ttattcattt gttatcactt
      121 attcaattta agggaggaaa tctaatgaaa gtagtttaca aatcaatcaa gccttacgga
      181 ttcgagcaaa tcattttgaa caatcaagaa aatatccctg aaaactgtac agagattaaa
      241 ccaccagttc ctaactggag accaagattt gattttgata aaaaacagtg ggttgagtta
      301 gctactgaag aagagaaaaa agggaatgct gttgatagcg tagatgaatt ggctaatatt
      361 aaggcattat acgaaacgct gaaggcagaa aatgatgaat tgaaacagct aaattctaaa
      421 gcaatgctaa acaatgtagc aatcaagcaa gaaaatgtct tattgaaaga aaagtcagaa
      481 agtttagcgc agttgaattc aaaaacgatg cttgcttctg tacaaaatac caaggaaatc
      541 gaagaaatca aaaaacaatt acaaggtggg aagtaacatg tattcatatg aagatatcaa
      601 actaatgtat gactggggct gtttcactaa cga
//
LOCUS       DACBYO010000264          612 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.278, whole genome shotgun sequence.
ACCESSION   DACBYO010000264 DACBYO010000000
VERSION     DACBYO010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..612
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.278"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
BASE COUNT          199 a           88 c           90 g          235 t
ORIGIN      
        1 aagactctat tattacaagt tcatccgttg taagatgggt ataggtcatt tgtactcact
       61 ccttataatt ctttggtcgg aactattttg agtgtagcac aaatgacttt tttagttgtc
      121 tagcttaatt ttacaatcgg cgacttattg cttttgcaaa atttatttac ctgttttctg
      181 gatcaacgat agtgtacatt atgctatcct tgtttggatt ttaggacgtt taaagaggca
      241 cttttttaca taacttaatc catagacctt ttaagcatgc tgtgagataa taataaagaa
      301 gagtttaaag cgcaccccaa accacttccc cataagtgta ttacgcttta aactctttta
      361 tatttgaatt cactaagaag cataccatat atttgaattt actaagaagc ataccatatt
      421 tttgaaaaaa agtgagaaaa aaggcttata attaggattt agagtaatta attagatgtt
      481 tattttatag gactgatact atagattaca aatagtatcg tatttcgcaa tcttaaaatt
      541 atcttcttac tgtgaataag ataataaaat ttgtatttgt cctttttagg taacttattt
      601 taatctatat ac
//
LOCUS       DACBYO010000265          597 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.279, whole genome shotgun sequence.
ACCESSION   DACBYO010000265 DACBYO010000000
VERSION     DACBYO010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.279"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..>597
                     /locus_tag="IVD26_003091"
     CDS             <1..>597
                     /locus_tag="IVD26_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAP6080972.1"
                     /translation="PSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENIEKQILALINS
                     MEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTILKECKFMIGN
                     SSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKIQDPQFIKSLK
                     NVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
BASE COUNT          262 a           76 c           91 g          168 t
ORIGIN      
        1 acctagtttt agagatataa aagaaaaata tcatctaaaa tttgaaaaga aaaaatacgt
       61 tttgcaagta tttcatccag ttgtaaccga actagaaaat atagaaaaac aaattttagc
      121 tttgatcaat tcaatggaac aacaatctca accaattatt tgcattttac ctaatagtga
      181 tgctggtagc gaaattatca gaaaaatgta ccagaaatat ttaaaaacgg atattattta
      241 tattacgaat ttagagccgg aggaatacct gactatatta aaagagtgca aatttatgat
      301 cggaaattct tcttctggga taattgaagc tgcatcattc aaaataccag taataaattt
      361 aggaaccaga caaaatggac gagaacaatc taaaaatatt ataaatgcaa atctaaatga
      421 aaatgaaatt gaaactgctt tgaataaaat acaagatcct cagtttataa aaagcttgaa
      481 aaatgttaag aacatctacg gtgacggcaa cagttctaga agaataacaa aaacattgaa
      541 tcaaatattg aatgatgggg aagatattaa gtggattcaa aaacaaatag cttatta
//
LOCUS       DACBYO010000266          578 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.280, whole genome shotgun sequence.
ACCESSION   DACBYO010000266 DACBYO010000000
VERSION     DACBYO010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.280"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            158..352
                     /locus_tag="IVD26_003092"
     CDS             158..352
                     /locus_tag="IVD26_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080973.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT          244 a           72 c           91 g          171 t
ORIGIN      
        1 agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa ctttcaaatt
       61 gattcttttt atttatcata aagatataga tacataatca ttttcactta catatatttg
      121 aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag aagtaaaaac
      181 aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc ctttacttgg
      241 ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa agaacgagct
      301 agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt aaatccaatg
      361 tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt atagaattag
      421 aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac catatgatta
      481 tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg aatcaaatat
      541 acttgtcatt catcatgaaa tatagagact tataaaat
//
LOCUS       DACBYO010000267          572 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.281, whole genome shotgun sequence.
ACCESSION   DACBYO010000267 DACBYO010000000
VERSION     DACBYO010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.281"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..523)
                     /locus_tag="IVD26_003093"
     CDS             complement(<1..523)
                     /locus_tag="IVD26_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080974.1"
                     /translation="MYSQTIDSLNKRFGNRVLKGIEIGYIASEKDRIIDYLADKDYDL
                     KLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSEALVVIEADVFAHFDYGFRVFGL
                     SVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLYDNLALYEYVIDLYLSRGGTLFS
                     VGSDGHYLEHFRFH"
BASE COUNT          199 a          109 c           93 g          171 t
ORIGIN      
        1 aatggaaacg gaaatgttca aggtaatgcc catctgatcc aacactaaac aaggtaccac
       61 cacgtgaaag atataaatcg atgacatatt catataacgc taaattgtca tacaagtaag
      121 cgctcttagc atttaattcg aatgccaatt tatttttgat tacttgatct agaatcggta
      181 aaaactgcgc ttcatattgt ttaaattcag caacggatag accaaatacc cgaaaaccat
      241 agtcaaaatg agcaaagaca tctgcttcta taacaactag tgcttctgaa agttgtgcaa
      301 aatactgagg aatcacaata gcaggatcca tatctttgac ttcgtcatct aaataatcaa
      361 attgaccatt atgatgcaca ctgagtaatt ttaaatcgta atctttatcg gctaaatagt
      421 cgatgatccg atccttttca gaagcgatgt aaccgatttc tatgcctttt aaaacacgat
      481 tgccaaaacg cttatttaag ctatcgattg tttgactgta catttcataa tcggggatat
      541 catcgacttt agtaacagga ttggctaagt ca
//
LOCUS       DACBYO010000268          565 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.282, whole genome shotgun sequence.
ACCESSION   DACBYO010000268 DACBYO010000000
VERSION     DACBYO010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..565
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.282"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(7..420)
                     /locus_tag="IVD26_003094"
     CDS             complement(7..420)
                     /locus_tag="IVD26_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HAP6080975.1"
                     /translation="MDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVLSASIPI
                     LIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEKLLYITK
                     TSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          198 a           73 c           65 g          229 t
ORIGIN      
        1 aaatttttag ttattaactt gattaaaatc agagataata tcatttaatt cagtttgaag
       61 ggttgtaacg attaaatgga aattttcttc atctgtttta ttatatgggg atgttttcgt
      121 tatatataac aacttttctt tttcaatttt cattaataac tctgtcgaag tctgtacttt
      181 atcttgataa ttaaatgcag acataccact ttgtataatt gtaattattg ctgaagcaat
      241 tgaaacaatc aatagtaaag acctgtgttc ggaagcctga tcaattaata ttgggatact
      301 agctgataag actattttta taatatttcc gataccaatt actctattat aaaatcgaat
      361 ttcttttttt aatctatcga ttgtagaatc aatagattcg ataaacgctt tttgatccat
      421 cattttctct ccaatcattt tattaaaatc attaacaaaa atattataat aggatttaag
      481 taagttctaa ctaatcacat ataaaaataa aaaaacattt gtattttatc aaagttttat
      541 tatacttgtc aatttgtgta catcc
//
LOCUS       DACBYO010000269          562 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.283, whole genome shotgun sequence.
ACCESSION   DACBYO010000269 DACBYO010000000
VERSION     DACBYO010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.283"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(44..>562)
                     /locus_tag="IVD26_003095"
     CDS             complement(44..>562)
                     /locus_tag="IVD26_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HAP6080976.1"
                     /translation="AIVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVK
                     EAFGRIPYSLTDVKLFHTDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTY
                     KSVKVEFVHQYQFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILD
                     NERGSDTSGEAA"
BASE COUNT          165 a          135 c           98 g          164 t
ORIGIN      
        1 atcctcggat ctgattttct ccggcagaag cacaatcatt caattacgct gcctctccag
       61 aggtatcaga tccgcgctca ttatcaagga ttcgcttcgc caatctctgt tgtcgaattt
      121 ggatcggtgt ttcatacgcc aacgtgccat gtaagcgtag atagttccac caatgcacat
      181 aatcaaacaa ttctagacgt agctgtgcca gtgtctcaaa ttggtattga tgcacgaatt
      241 ctactttgac agatttatag gttgattcca caacggcatt atcatacgga caacccttcc
      301 tactcaatga acgagtaatt ccaaaaccat tcagaatctc atgaatggtt tggttatcaa
      361 attcctttcc ccggtctgta tgaaaaagct tgacgtctgt taaagaatac ggtatccgtc
      421 caaaggcttc ttttaccaat gaggcatctt tcttctcacc acaggaataa ccaataattt
      481 ctcgattaaa caaatcaagt attaagcaga tataatgcca ctttttcccc acgcgaacat
      541 aagtaagatc cgtaacgatg gc
//
LOCUS       DACBYO010000270          541 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.284, whole genome shotgun sequence.
ACCESSION   DACBYO010000270 DACBYO010000000
VERSION     DACBYO010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..541
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.284"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            3..488
                     /locus_tag="IVD26_003096"
     CDS             3..488
                     /locus_tag="IVD26_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080977.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
BASE COUNT          169 a          105 c           93 g          174 t
ORIGIN      
        1 tcatgcataa agggatttac gcaggcttgt tgggaactgt aatacttttt tctgcctgtg
       61 gatataaaac aaagaattct gttaaagaat cttcagcagc catttcaaca actgaggttg
      121 gttcaactaa aagtacttct actacttcca ttactaatac ttctactggt aatgtagatt
      181 cgcaacatag ccaatcaagt attcagtcgt ttagcatttc ttcaacatct gaaatgcaag
      241 aaagcactgt accttctctt ccattagaaa actctgacaa agcacttcta tttcttattg
      301 cccaccgttc cgaattacaa agtgacgata ttgttattag cttttatcaa aaaattgatc
      361 gagattattt gttcacagct tccagcaaac aaatccgttc ccaaggagga tctggaagcg
      421 ttggttttta tcgagtgtca cccgaaggat cgattacgat gacagatgca aatggaacac
      481 cattttgatt agatgatatt atacggattt acagtactag caagtcatta ttggtatcat
      541 t
//
LOCUS       DACBYO010000271          537 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.285, whole genome shotgun sequence.
ACCESSION   DACBYO010000271 DACBYO010000000
VERSION     DACBYO010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.285"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..365
                     /locus_tag="IVD26_003097"
     CDS             <1..365
                     /locus_tag="IVD26_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP6080978.1"
                     /translation="VLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGD
                     AVDQEMYKQAQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELF
                     ISILKELEEHENWYAEVE"
BASE COUNT          211 a           78 c          117 g          131 t
ORIGIN      
        1 tcgtcttaca gacccaagta aaatcgatga gaaatgcgat gcaatatctt gagtatatgg
       61 acttttttgt gaaagaattt gatacaaatt tatatgttgc tggtgttatt cctttcatgt
      121 tggaaagcgg tgacgcagta gatcaggaaa tgtataaaca agcccaagag atttatgggg
      181 aacatttgat taaaaatgtt gtactcaaaa atgcgcgctt aaaacgatac gacggatcag
      241 gtattacgat ggagaagaca aagaaaggtc tcttaaaaca atgggatcgc aaaagccacg
      301 aattatttat cagtattttg aaagaattgg aagaacacga gaattggtat gcggaggtgg
      361 agtaattggc tgacatcaaa ggacttgata tttttgggaa caacaaagga ctcgccaaaa
      421 taaaaaaaga agcagaagca aagaaaaagc agcaagcaat tacaccatct gaaaataagc
      481 aattagaagt gcaccaagtt caagaaataa aaacttcctc caatgttgaa agacaga
//
LOCUS       DACBYO010000272          533 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.286, whole genome shotgun sequence.
ACCESSION   DACBYO010000272 DACBYO010000000
VERSION     DACBYO010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.286"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..>533
                     /locus_tag="IVD26_003098"
     CDS             <1..>533
                     /locus_tag="IVD26_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HAP6080979.1"
                     /translation="DADKYTPMVEGEKVEVGGTVDLTDNVTNLPTLPEGTTVTDVTPD
                     GTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYNPEGQKVTTDLNKEP
                     DASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGIVVVTYPDGSKEEVEVTISVEDKK
                     APNKPQVDPITEGDQIVT"
BASE COUNT          217 a           86 c          117 g          113 t
ORIGIN      
        1 gatgccgata aatatacacc aatggtagaa ggtgaaaaag tagaagttgg aggcacagta
       61 gatctaacag ataatgttac taacttgcca acattaccag aaggaacaac agtaacagat
      121 gtcactcctg atggtacgat tgataccaac acaccaggta attacgaagg ggttatcgaa
      181 gtaacgtatc cagatggtac gaaagataca gtgaaagttc cagtagaagt gacagacaat
      241 cgttccgatg ccgataaata caatcctgaa ggacaaaaag tgactacaga cttaaataaa
      301 gagccagacg catctgaggg aattaagaac aaagaagatc taccaaaagg aactacttat
      361 acttggaaag agaaagtaga tgttagtaca gctggaaaca aaaaagggat tgtagtagta
      421 acatatccag atggatctaa agaagaagta gaggttacta tttctgtaga agataaaaaa
      481 gcaccgaata aacctcaagt tgatcctatt acagagggtg accaaattgt tac
//
LOCUS       DACBYO010000273          530 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.287, whole genome shotgun sequence.
ACCESSION   DACBYO010000273 DACBYO010000000
VERSION     DACBYO010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.287"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            312..428
                     /locus_tag="IVD26_003099"
     CDS             312..428
                     /locus_tag="IVD26_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAP6080980.1"
                     /translation="MIGLNAISAKYCKFKAFVEKFTERQTDKIIQYHITYTD"
BASE COUNT          224 a           50 c           69 g          187 t
ORIGIN      
        1 taataaagaa ttgaacttct gagaaaacaa agaatctttt ttcttttttt gaattgactc
       61 atggattggc gttaaaattt tattttgaaa aagttatttc tggtttaact caaaaaaaga
      121 gatatgaatc taatagtgat agaaaggatg ttatttttca tgaaatggtt gttttagatt
      181 taatacatat aactaataaa tgctattgaa tgtatttaaa ctaattaaca aaagaatttg
      241 aattgttaat aaaatccaat aaaatatatt aataaagtag atagaaataa aaaaacaaag
      301 actaaacata tataattgga ttaaacgcaa tatctgcaaa atattgtaaa tttaaagcct
      361 ttgtagaaaa atttactgaa agacaaactg ataagattat tcagtatcat attacctata
      421 ctgattaaaa ttttttgaaa cgggatacta aataaaaaat ttatttataa cagaactaat
      481 tatttaatgc ggatgcgcca atacttggtc ctgcaagagc tatttatttt
//
LOCUS       DACBYO010000274          528 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.288, whole genome shotgun sequence.
ACCESSION   DACBYO010000274 DACBYO010000000
VERSION     DACBYO010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.288"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(5..90)
                     /locus_tag="IVD26_003100"
     tRNA            complement(5..90)
                     /locus_tag="IVD26_003100"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="IVD26_003101"
     tRNA            complement(107..178)
                     /locus_tag="IVD26_003101"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="IVD26_003102"
     tRNA            complement(190..262)
                     /locus_tag="IVD26_003102"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="IVD26_003103"
     tRNA            complement(280..361)
                     /locus_tag="IVD26_003103"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="IVD26_003104"
     tRNA            complement(369..441)
                     /locus_tag="IVD26_003104"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="IVD26_003105"
     tRNA            complement(445..517)
                     /locus_tag="IVD26_003105"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DACBYO010000275          523 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.289, whole genome shotgun sequence.
ACCESSION   DACBYO010000275 DACBYO010000000
VERSION     DACBYO010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.289"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(270..>523)
                     /locus_tag="IVD26_003106"
     CDS             complement(270..>523)
                     /locus_tag="IVD26_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080981.1"
                     /translation="DHPLNLTLNNGLLSFVLAGYVDYEYSPDYLEKPLQHENNDINFR
                     FVYESKSKTWLVDQLSTINTSFHELPKPENEVEMVIKIF"
BASE COUNT          189 a           67 c           95 g          172 t
ORIGIN      
        1 aatgaaaaac gagaaggaag atgactttaa agtagtttag tatgaaggtc gattgataaa
       61 acgatgtgga ttaatgctaa ataatgagta atttttcaat aatacaaaaa ctgtgtacag
      121 tattagaagt agagaaacgc tagcgtcgaa aaaaagatat ttttcgtgaa aagtaatagg
      181 ggctaaaaag aaagtataca atttatttat gtttctaagc atataaaaaa gagcgttgaa
      241 aggaatattt ccccttcaac gcttcttttt tagaagattt taatgaccat ctcaacttca
      301 ttttcaggtt taggtaattc atggaagctt gtgtttatcg tgcttaattg atcaactaac
      361 catgttttac tttttgactc gtagacaaat ctaaaattaa tatcattgtt ctcgtgttga
      421 agaggtttct ccaaataatc tggtgaatat tcatagtcaa cgtaacctgc taatacaaaa
      481 gaaagcagtc cattatttag tgtcagattt aacggatggt cgt
//
LOCUS       DACBYO010000276          519 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.290, whole genome shotgun sequence.
ACCESSION   DACBYO010000276 DACBYO010000000
VERSION     DACBYO010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.290"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..370)
                     /locus_tag="IVD26_003107"
     CDS             complement(<1..370)
                     /locus_tag="IVD26_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015075118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAP6080982.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGT"
BASE COUNT          190 a           90 c           71 g          168 t
ORIGIN      
        1 gcgttccgaa aaaggtcgta gaaccaaaga tcgtcaggac acgcaacgtt gtttgcttat
       61 cccctttata gcttaagaaa aaaggttttg aaactagaat aagaataata taaataacta
      121 atccccaaat caagacattg attccttgca tcagtaattc tgtattgata tcttgcatga
      181 aagctcgaaa tgccagtgct ggcaaagcca ctgttaagac gactttcgat agaatttttc
      241 caacagattc agaaaaaatc cccttttttc tacaaacaaa ccctaataat ataataaaaa
      301 ctgttgaagt gattgcactg acaatcgaca tatctgtcaa agtcgatcga aaaatgtcaa
      361 ataagttcat ctttctcctc ctaattatgt tcatttattc acaataaaaa aagcttttat
      421 tttgctaata cgtattaaca tttttaattt tatctttaca ttgttactta ttgaacaata
      481 ggaaattaaa gaaacttttg aaacttatgt aaagtgatt
//
LOCUS       DACBYO010000277          518 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.291, whole genome shotgun sequence.
ACCESSION   DACBYO010000277 DACBYO010000000
VERSION     DACBYO010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.291"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(36..>518)
                     /locus_tag="IVD26_003108"
     CDS             complement(36..>518)
                     /locus_tag="IVD26_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080983.1"
                     /translation="FFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLIN
                     HIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRN
                     NLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE
                     "
BASE COUNT          163 a           92 c           83 g          180 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaa
//
LOCUS       DACBYO010000278          513 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.292, whole genome shotgun sequence.
ACCESSION   DACBYO010000278 DACBYO010000000
VERSION     DACBYO010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.292"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(107..>513)
                     /locus_tag="IVD26_003109"
     CDS             complement(107..>513)
                     /locus_tag="IVD26_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_465591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAP6080984.1"
                     /translation="TPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMNA
                     ASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYEDS
                     QITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          162 a          102 c           78 g          171 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttc
//
LOCUS       DACBYO010000279          511 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.293, whole genome shotgun sequence.
ACCESSION   DACBYO010000279 DACBYO010000000
VERSION     DACBYO010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.293"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..291)
                     /locus_tag="IVD26_003110"
     CDS             complement(<1..291)
                     /locus_tag="IVD26_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080985.1"
                     /translation="MSPESNDDDKYFANKLFQFIFPDYSSMPFFTLINFMLYVKEHLG
                     YDDLVEMIKAYDKEPYPFKGINTGSDMAMISGETVEEILANYKEQNIKTLELI"
BASE COUNT          171 a           73 c           63 g          204 t
ORIGIN      
        1 aattaattcc agagttttta tattttgttc tttgtaatta gctagaattt cttctacagt
       61 ttcgcctgaa atcatagcca tatctgaacc agtattgatt cctttgaatg gataaggttc
      121 tttatcatat gcctttatca tttctactaa atcatcatat cctaagtgtt ctttaacata
      181 cagcataaaa tttattaatg taaaaaatgg cattgaagaa tagtctggaa atataaattg
      241 aaacagtttg ttcgcaaaat atttatcatc atcattgctt tctggtgaca ctgacaggct
      301 gctaagccac tttaaataca attcaaatat aattatttgt ttttgtgaat tatcttcatt
      361 ctcatcataa ataagtttat cgggtaaaag attatctaag ttatctacta aagataggct
      421 attagctttc ttggcataag atattaattt taaaatatta ttatttagga ataatctata
      481 ttcttctcca gataattctt ctaaaaattg t
//
LOCUS       DACBYO010000280          511 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.294, whole genome shotgun sequence.
ACCESSION   DACBYO010000280 DACBYO010000000
VERSION     DACBYO010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.294"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..442)
                     /locus_tag="IVD26_003111"
     CDS             complement(<1..442)
                     /locus_tag="IVD26_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080986.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTI"
BASE COUNT          170 a           80 c           72 g          189 t
ORIGIN      
        1 taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg atcaattggc
       61 tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat cgttcattca
      121 accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat ttatcatgaa
      181 gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct aatactcctt
      241 ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca atatctaaag
      301 aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc tttttttcat
      361 aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt tttataatta
      421 taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga ttatataaaa
      481 aaagccgaat gtttttagga ttccctgtca a
//
LOCUS       DACBYO010000281          509 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.295, whole genome shotgun sequence.
ACCESSION   DACBYO010000281 DACBYO010000000
VERSION     DACBYO010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.295"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            23..>509
                     /locus_tag="IVD26_003112"
     CDS             23..>509
                     /locus_tag="IVD26_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HAP6080987.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FM"
BASE COUNT          186 a           92 c           85 g          146 t
ORIGIN      
        1 tcacagaaaa gaggacttcc ctatgaatga ttttactaca gaaattgtgc aaactctagt
       61 cactaaaggc gatttaaatg aattattccg ttcgcactta gaaaaagcga taaacacact
      121 cctacggact gaattaacgg cttttttaga ttacgaaaaa tatgatcgca ctggttttaa
      181 ttcaggtaat tcgagaaacg gttcttactt tcgatcaatc aaaaccgaat atggtgaatt
      241 aacattggaa atacctagag atcgtaatgg tgagtttaaa caacaaactt taccagccta
      301 caaaagaaca aacgatacat tggaaaccac tattatccat ttattcgaaa aaggtgttac
      361 gatgtctgaa attgctgatt tgatcgaaaa aatgtacggt catcactata ctccacaaac
      421 catgtccaac atgactaaag ttctgactga agaagtaaat gcctttaaat ccagagcctt
      481 aaatgataag tatgtcgcta tttttatgg
//
LOCUS       DACBYO010000282          509 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.296, whole genome shotgun sequence.
ACCESSION   DACBYO010000282 DACBYO010000000
VERSION     DACBYO010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.296"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..132)
                     /locus_tag="IVD26_003113"
     CDS             complement(<1..132)
                     /locus_tag="IVD26_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP6080988.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          183 a           93 c           91 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactatta
//
LOCUS       DACBYO010000283          508 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.297, whole genome shotgun sequence.
ACCESSION   DACBYO010000283 DACBYO010000000
VERSION     DACBYO010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.297"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
BASE COUNT          228 a           70 c           81 g          129 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactc
//
LOCUS       DACBYO010000284          486 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.298, whole genome shotgun sequence.
ACCESSION   DACBYO010000284 DACBYO010000000
VERSION     DACBYO010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.298"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            1..270
                     /locus_tag="IVD26_003114"
                     /pseudo
     CDS             1..270
                     /locus_tag="IVD26_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876065.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
BASE COUNT          181 a           72 c           87 g          146 t
ORIGIN      
        1 aaatctatat tttgatatac aaattacagc ttcagatact aagttgcata aaccttttcc
       61 ggaccccata caaaaggcaa ttgatgaatt gggcataaaa aataagaaac gatttatatt
      121 ggtgattcat tatatgacat gcaaagtgcg aaagcttgtg ggatagcatt tggtttagct
      181 aaatggggag ccaaaaatat agaaaatttt caaagtgtag atataattat tgattctcct
      241 caagaaatac ttgatttgtt agaaaaatag acaaagagcg tgagataagg atagggtctc
      301 acgctctttg tttttcgcca tttaaagatt gaaatttttg ccatcgccga ttgtaaaatt
      361 aagctagaca actaaaaaag tcatttgtgc tacactcaaa atagttccga ccaaagaatt
      421 ataaggagtg agtacaaatg acctataccc atcttacaac ggatgaactt gtaataatag
      481 agtctt
//
LOCUS       DACBYO010000285          480 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.299, whole genome shotgun sequence.
ACCESSION   DACBYO010000285 DACBYO010000000
VERSION     DACBYO010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.299"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..390
                     /locus_tag="IVD26_003115"
     CDS             <1..390
                     /locus_tag="IVD26_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP6080989.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          183 a           85 c           74 g          138 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc
      361 gatacattag tttcaatgtt tactgagtaa ctaattattt tgcaggagga caatttattt
      421 acacaaaatt attgacgctc ccaattagga ctcaattgtt catagatgag catttgtaat
//
LOCUS       DACBYO010000286          472 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.300, whole genome shotgun sequence.
ACCESSION   DACBYO010000286 DACBYO010000000
VERSION     DACBYO010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.300"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            217..>472
                     /locus_tag="IVD26_003116"
     CDS             217..>472
                     /locus_tag="IVD26_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP6080990.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEF"
BASE COUNT          147 a           91 c           88 g          146 t
ORIGIN      
        1 ttagctttac tggttcgctt acttttcttg ttaatatctt ggactttaca tcatcgatat
       61 tgcttatttt atcaagctta aataatttac aaattaattt cgtactagtt tttatatttg
      121 acgagagtgt aaaatatttt gtgtaaatag aaaaaaggaa gtcccttctg tagaatagag
      181 ttaccacaac acattcacag aaaagaggac ttccatatga acgattttac tacagaaatt
      241 ctaaagactc tagcgaacaa aggcgatttg aatgaattat tccgtgtcca tttggaaaaa
      301 gctgtcaata cgcttctcaa aacggagtta acggctttcc tcgattacga aaagtacgat
      361 cgcattggtt ttaacacggg gaattctcgt aacggctcct atgaccgtac ggtcaagacc
      421 gagtacgggg aacttcatct ccagattccg cgcgaccgca acggcgagtt ca
//
LOCUS       DACBYO010000287          471 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.301, whole genome shotgun sequence.
ACCESSION   DACBYO010000287 DACBYO010000000
VERSION     DACBYO010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.301"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(212..>471)
                     /locus_tag="IVD26_003117"
     CDS             complement(212..>471)
                     /locus_tag="IVD26_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015077585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP6080991.1"
                     /translation="KYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRR
                     REKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          166 a           59 c           82 g          164 t
ORIGIN      
        1 tgtttatgga attaaaaata ttaaacagga atttatcgaa aatggtagaa aagaaattta
       61 taaaaggact tataaagatt gattatataa tatatgaaaa gctattataa aagacattag
      121 tattaaatag tttaaaaaaa tgaaaaataa taaaggaagt gagtcaattc cagactcctg
      181 tgtaaaatgc tatacaatgt ttttaccatt tctacttatc aaaattgatg tattttcttg
      241 aagaataaat ccattcatca tgtaggtcca taagaacggc tccaattaag cgattggctg
      301 atgtttgatt ggggaagatg cgaataatct tttctcttct gcgtacttct tgattcagtc
      361 gttcaattag attggtactc tttagtcgat tgtgggaatt tccttgtacg gtatattgaa
      421 aggcgtcttc gaatccatca tccaatgatg cgcaagcttt tgaatatttt g
//
LOCUS       DACBYO010000288          458 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.302, whole genome shotgun sequence.
ACCESSION   DACBYO010000288 DACBYO010000000
VERSION     DACBYO010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.302"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
BASE COUNT          156 a           63 c           56 g          183 t
ORIGIN      
        1 ctagtgggct gattttttat atattttagt ttacataata tatattatac aaagtagatt
       61 taaaaaatga taaacctctc tcgaacggtt ttttatcaaa aatcgtcatt tttccatcaa
      121 aatctgctta tgcaaaatta taaaaaaatt ttgcagtttt tcttactttt tttgtcgttt
      181 aattgaatga taaaaaccag tttctttatt cagttaatca aatatgaacg aattagatat
      241 gaatcattgt atttgccgtt gcggaaggat tttttaatta accacagata aacattgata
      301 acgattcgct tattgtaatc aacagattaa atttcatatg ttcatatgta cggatacatt
      361 ttcggaccga ttaattttaa ccattctatt tatttgctta cctattagat atcaataaaa
      421 aactgcttaa cagctatttc agctgttaag cagtttta
//
LOCUS       DACBYO010000289          455 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.303, whole genome shotgun sequence.
ACCESSION   DACBYO010000289 DACBYO010000000
VERSION     DACBYO010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.303"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..242)
                     /locus_tag="IVD26_003118"
     CDS             complement(<1..242)
                     /locus_tag="IVD26_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016438386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma-70"
                     /protein_id="HAP6080992.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETL"
BASE COUNT          154 a           87 c           58 g          156 t
ORIGIN      
        1 agtgtttcat cagatacata aattgtaaag tgcaagactt taaatgatac acaatcataa
       61 aaacaggtat caatcgttcc acgttcaact tgtttcgttt cggctatttc acaaaacaat
      121 acttcacgtt tagaatgtct tgcaagctgt ctgtttcgac ttttcacttt gttcttaatg
      181 acaatcagca ttaaagaatt gaactgtaat ctgacgatat gctcgaaaga agatgtcctc
      241 ataatctcac cccctttctg ctaatgctga aatatataaa cggaataccg tttataccct
      301 ttagaaatac agaaaaatgg taagaaaaaa gcccacacaa aacatatatt tgtgcgagcc
      361 ttaaatactg caatattact ctttctttta taacactatc cttttagcag atttcaaatt
      421 ttcttttata tattgttttt agcctaacat actat
//
LOCUS       DACBYO010000290          455 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.304, whole genome shotgun sequence.
ACCESSION   DACBYO010000290 DACBYO010000000
VERSION     DACBYO010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.304"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..430)
                     /locus_tag="IVD26_003119"
     CDS             complement(<1..430)
                     /locus_tag="IVD26_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP6080993.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          131 a           90 c           58 g          176 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatt
//
LOCUS       DACBYO010000291          421 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.305, whole genome shotgun sequence.
ACCESSION   DACBYO010000291 DACBYO010000000
VERSION     DACBYO010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.305"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            188..385
                     /locus_tag="IVD26_003120"
     CDS             188..385
                     /locus_tag="IVD26_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080994.1"
                     /translation="MKFICLSCGEKESIPMDVVKFLDDADIANDPNNPPQFTCEKCGK
                     EMYPEYYRNALGIEFKISDVQ"
BASE COUNT          164 a           57 c           95 g          105 t
ORIGIN      
        1 tatgaattcg ttgggatgag tgtgcgcaaa aatggacggt tagttattaa atatgcgaaa
       61 gataaccatg caaagcggtt tatgcgagag gagaatcgaa aaattgacca aaaagaattc
      121 aggcaacagt atgaagaaga aaaagaaaaa acttttaaag caattcgctg ggattgggaa
      181 cgccaacgtg aaatttatat gtctaagttg tggtgaaaaa gaatcaatcc caatggatgt
      241 agtaaaattt ttagatgatg cagatattgc aaatgatccg aacaatcctc cccaatttac
      301 ctgtgaaaaa tgtgggaagg agatgtatcc agaatattat agaaacgccc ttggaataga
      361 gtttaagatc agtgatgttc aataagaagg ttaatcatac aaaaagtcca ccggagaatt
      421 c
//
LOCUS       DACBYO010000292          411 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.306, whole genome shotgun sequence.
ACCESSION   DACBYO010000292 DACBYO010000000
VERSION     DACBYO010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.306"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(257..>411)
                     /locus_tag="IVD26_003121"
     CDS             complement(257..>411)
                     /locus_tag="IVD26_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAP6080995.1"
                     /translation="SNKDKYKSELEKIATEAKTLDTEFMDKTIRKVMKKDNVTIKDPY
                     VKNIFK"
BASE COUNT          135 a           60 c           68 g          148 t
ORIGIN      
        1 tgaagcgata cggcaagtga aaaaataggg aagcatgaaa gaatctactt aatggcgcat
       61 tgattcatgt gatagaaata aaaaactttt ttaaattata tcctcatgat tgtaacaaat
      121 ccagtgattt gttttggtac aaataaaaaa aggccccgat gaagttgtgg caaaagtggt
      181 ttgcctcaaa aataagaagg aatttccaaa aatcacttct caaattttgc cacatcccca
      241 attgggtcaa atttgtttat ttgaatatat tttttacata aggatcttta atagttacat
      301 tgtctttttt catcacttta cggattgttt tatccatgaa ttccgtatca agagtttttg
      361 cttcggtagc aattttttct agctcagatt tgtatttgtc tttattagaa c
//
LOCUS       DACBYO010000293          398 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.307, whole genome shotgun sequence.
ACCESSION   DACBYO010000293 DACBYO010000000
VERSION     DACBYO010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.307"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..188)
                     /locus_tag="IVD26_003122"
     CDS             complement(<1..188)
                     /locus_tag="IVD26_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080996.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYP"
BASE COUNT          112 a           84 c           67 g          135 t
ORIGIN      
        1 aatggataat cttctgtcgc atcgacgaac gtcttcgtag tcagatttaa cgttaaaata
       61 tcgctacttt gataagcttt tgccgctttg tctgtgacga caaaagatct gcctgtttga
      121 atttctgtca caaaaacgag attgtctctg cttttttcaa caacaactcc aatcgttgaa
      181 tgaaccattt ctgcttcctc ccttctcttt cttttgatat aatgtagtcg caaatcgcac
      241 cactcaatga gttggcggaa aacaattcat tgaaaaaaag agtcctggac aatcacgttc
      301 aggactcttt tacttctttt attcacttaa caactaacac tctgtgagtg aaatggactc
      361 ttcaatgtga tgttaggatg atttcatgga cacgattt
//
LOCUS       DACBYO010000294          391 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.308, whole genome shotgun sequence.
ACCESSION   DACBYO010000294 DACBYO010000000
VERSION     DACBYO010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.308"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            32..259
                     /locus_tag="IVD26_003123"
     CDS             32..259
                     /locus_tag="IVD26_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080997.1"
                     /translation="MGFRTKRSTSSEKKWVYSQTIFYGGVISISLLSSTLYSFNVIDV
                     SMSNFISIIGILISAIITQLLLVFEEKSKNN"
BASE COUNT          125 a           49 c           64 g          153 t
ORIGIN      
        1 ttggtttttt gataagagta gaaatgcagg gataggtttt agaaccaaac gaagtacgtc
       61 ttctgaaaaa aagtgggtat attcacagac tattttttac ggaggggtta tttcaatcag
      121 tttactttct tcaacacttt attcttttaa tgttatagac gtttccatgt caaattttat
      181 atctattatt ggaatcctta tttctgcaat tattacacaa ctacttcttg tgtttgaaga
      241 gaagtcaaaa aataattaaa gcaattatgc cttttagtac aggaattatt acttcttaca
      301 aatgtatagc gaatgtgaag cctgctgttt taattgttct agaaaaactt ttgagtgaac
      361 aattatttta tgttaggatg aattaatttc t
//
LOCUS       DACBYO010000295          376 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.309, whole genome shotgun sequence.
ACCESSION   DACBYO010000295 DACBYO010000000
VERSION     DACBYO010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.309"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            82..>376
                     /locus_tag="IVD26_003124"
     CDS             82..>376
                     /locus_tag="IVD26_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAP6080998.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTH"
BASE COUNT          133 a           62 c           76 g          105 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccatt
//
LOCUS       DACBYO010000296          373 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.310, whole genome shotgun sequence.
ACCESSION   DACBYO010000296 DACBYO010000000
VERSION     DACBYO010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.310"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(<1..299)
                     /locus_tag="IVD26_003125"
     CDS             complement(<1..299)
                     /locus_tag="IVD26_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6080999.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTP"
BASE COUNT          141 a           59 c           48 g          125 t
ORIGIN      
        1 ggagttgtca aagagaaaat taattctgct aagcttatta ttgaaaatac tgataactta
       61 taattatatc gtccattgac aatcaaatat aaactaacta tacttgttag aacaaaaaaa
      121 caggcgttga cttgttcttg attagttaaa aatatcaata aaggaatact tacccaatat
      181 atttttctat ttatttcttc tcctcttaag agttgaaaaa acggataaaa agttagtaaa
      241 ctaaatgcta ctggccactg atagttcaag gtggttgctc tccaaccggt ttcccccatt
      301 actgtcaatg gtattaaaca gtatatagag caaaccaata ataaattttt aacatttatt
      361 ttctcaaaaa cat
//
LOCUS       DACBYO010000297          355 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.311, whole genome shotgun sequence.
ACCESSION   DACBYO010000297 DACBYO010000000
VERSION     DACBYO010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.311"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            141..>355
                     /locus_tag="IVD26_003126"
     CDS             141..>355
                     /locus_tag="IVD26_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6081000.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEK"
BASE COUNT          159 a           45 c           51 g          100 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaaga
//
LOCUS       DACBYO010000298          331 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.312, whole genome shotgun sequence.
ACCESSION   DACBYO010000298 DACBYO010000000
VERSION     DACBYO010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.312"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
BASE COUNT           95 a           87 c           48 g          101 t
ORIGIN      
        1 atactaaacc ccaagttaaa cccctccttc gcgctgtcgc taataaaaag agtgtaaacc
       61 tttctgttac tctttgacaa agagtaacat tttcctaatt gtgacatggc tgtcacaatt
      121 ccaaatgctc tccgagggta ttcgctgtca caagtgacaa cgaaaaaagg agccgaaagc
      181 gtgtcacgct ctcaactcct tttacgcttt attttgcttc acgcaaaata atcgcttatc
      241 gtaaactcac gtcattaaac attgacgtaa atttactctc actcatctga cttttcttat
      301 tcggtatcac ttctctgtca cgtccaaacc c
//
LOCUS       DACBYO010000299          331 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.313, whole genome shotgun sequence.
ACCESSION   DACBYO010000299 DACBYO010000000
VERSION     DACBYO010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.313"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..>331
                     /locus_tag="IVD26_003127"
     CDS             <1..>331
                     /locus_tag="IVD26_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP6081001.1"
                     /translation="KRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGL
                     YTKTEHRTVKYLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGT
                     LFGFSVST"
BASE COUNT          111 a           70 c           67 g           83 t
ORIGIN      
        1 gaaacgggat acgcaagcag cctatgcttt cttaaaacga ctccataaac agtttggtga
       61 gccgaaagca attgtgaccg ataaagcacc ttctcttggc tccgccttta gaaagttaca
      121 gagtgtgggt ttatatacta agacagagca ccgaactgtg aagtatctta acaatttaat
      181 agaacaagac catcgaccta ttaaacgacg aaataaattt tatcaaagtc tccgtacagc
      241 ctcttccacg attaagggca tggagaccat tcgaggaata tataaaaaga accgaagaaa
      301 tggaacgctc ttcggctttt cggtgtctac t
//
LOCUS       DACBYO010000300          307 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.314, whole genome shotgun sequence.
ACCESSION   DACBYO010000300 DACBYO010000000
VERSION     DACBYO010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.314"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            10..216
                     /locus_tag="IVD26_003128"
     CDS             10..216
                     /locus_tag="IVD26_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018595044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP6081002.1"
                     /translation="MICKASSGDEMAVKEILKFYDGYISKLCLRPFYHSESGKIIMQV
                     DEELKGEIHTDMMKAILKFEIGVK"
BASE COUNT          104 a           41 c           64 g           98 t
ORIGIN      
        1 tcttttgaat tgatttgcaa agcgtcaagc ggagatgaaa tggcagttaa agagattttg
       61 aagttttatg acggttatat ttctaaatta tgcttgcgtc ctttttacca ctctgaaagt
      121 ggtaaaatca ttatgcaggt tgatgaagaa ctaaaaggag aaattcatac agacatgatg
      181 aaagcaatat tgaaatttga aatcggagtg aagtaatcaa ctgtataaaa aaatcgggag
      241 atacacagtt tcgtgttatc tcccttagta gttttacggt catatcaagg ctcattcaat
      301 cgtggta
//
LOCUS       DACBYO010000301          291 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.316, whole genome shotgun sequence.
ACCESSION   DACBYO010000301 DACBYO010000000
VERSION     DACBYO010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.316"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..>291
                     /locus_tag="IVD26_003129"
     CDS             <1..>291
                     /locus_tag="IVD26_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6081003.1"
                     /translation="ATISRHSSGKYYISLLCKEEVRELPKSNSAVGIDLGIIDFAILS
                     TGQKFDNNKFTSKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVA"
BASE COUNT          110 a           48 c           46 g           87 t
ORIGIN      
        1 gctacaatat cacgtcattc tagcggtaaa tattatattt ctttgttatg caaagaagaa
       61 gttcgcgaac tacctaaatc taattctgct gttggtattg acctaggtat tatagacttt
      121 gcaattcttt ctaccggtca aaaatttgat aataataaat ttacgtccaa aatggaaaag
      181 aaactcaaac gtgaacaacg taagttgtca agacgtgcct tattagctaa acaaaaaggt
      241 atcaatctgt ttgaagctag aaattatcaa acacaaaaac gtaaagtagc a
//
LOCUS       DACBYO010000302          289 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.317, whole genome shotgun sequence.
ACCESSION   DACBYO010000302 DACBYO010000000
VERSION     DACBYO010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.317"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..>289
                     /locus_tag="IVD26_003130"
     CDS             <1..>289
                     /locus_tag="IVD26_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6081004.1"
                     /translation="RKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTKILF
                     SNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKID"
BASE COUNT          119 a           36 c           37 g           97 t
ORIGIN      
        1 ccggaaaatc ggttcttcct ttaaacgtaa aattaacttg ttaactaacc ataatcaatt
       61 tttctcggat gatttatccg tttatgatga aatttttata cagggggaaa attatttcac
      121 aaaaatactt ttctccaatg tttacaaaaa aaatccagat gtaaaactaa attatataga
      181 agatggtttg ggtacttatt tgaagaagag tatattttca acaagtaaaa acgttcaaag
      241 agtttttaaa atattaaata aaaatagcat cttcaaaaaa aaaattgac
//
LOCUS       DACBYO010000303          274 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.318, whole genome shotgun sequence.
ACCESSION   DACBYO010000303 DACBYO010000000
VERSION     DACBYO010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.318"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
BASE COUNT          117 a           36 c           25 g           96 t
ORIGIN      
        1 attataaatt cactgcttat tgtaagtcta aatttctcac aaaacatata ctaattatac
       61 ctaatttaag taagtacaaa catcatttta agaataggaa aggacattta tatactattc
      121 tctgtatttt tgatttataa ataaatatga attgaatcca aatcagctat attactattt
      181 tataataacc aactataaaa aacgaagtta ggtgaaaaac taacttcgat attcataaaa
      241 gactctatta gttcaactta gcaaaagatt taaa
//
LOCUS       DACBYO010000304          270 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.319, whole genome shotgun sequence.
ACCESSION   DACBYO010000304 DACBYO010000000
VERSION     DACBYO010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.319"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..>270
                     /locus_tag="IVD26_003131"
     CDS             <1..>270
                     /locus_tag="IVD26_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAP6081005.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGW"
BASE COUNT           83 a           56 c           53 g           78 t
ORIGIN      
        1 atccatcgtc gtttctacac cagtatctgc catcagaaaa tcacgacgga tacaactgaa
       61 tttaaatacc atgaagtgga tgccaaaggc attatccgtc aaaagaaatt gtatctagat
      121 ccttttatgg atatgttcaa tagtgagatt ttatcctatc gtatctctga aaagcccaat
      181 gcattagcgg taatggaagg tttggaggaa gctatccaga ccactaacga ttgtccctat
      241 cgtcgtacgt ttcactcaga tcaaggttgg
//
LOCUS       DACBYO010000305          266 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.320, whole genome shotgun sequence.
ACCESSION   DACBYO010000305 DACBYO010000000
VERSION     DACBYO010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.320"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(34..>266)
                     /locus_tag="IVD26_003132"
     CDS             complement(34..>266)
                     /locus_tag="IVD26_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP6081006.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           78 a           39 c           47 g          102 t
ORIGIN      
        1 agaaggactg accttctgtc tcagattttt ttgttatttc acttgaatca attgattgat
       61 caaaaaaatc ctgattttca tgttctcaaa tgatttaaat ccataagata atcgtttcag
      121 tgtcttgata tggggaatct tggcctctat tttgccatta gaatacgggt aaatcatagc
      181 attgtaaata ccttcttcat acgttaaaag gttttgaagt ttcgtgcgaa gttgtgcatc
      241 aagtgtttca ggaagatttt ttaata
//
LOCUS       DACBYO010000306          266 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.321, whole genome shotgun sequence.
ACCESSION   DACBYO010000306 DACBYO010000000
VERSION     DACBYO010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.321"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..>266
                     /locus_tag="IVD26_003133"
     CDS             <1..>266
                     /locus_tag="IVD26_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP6081007.1"
                     /translation="QDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHTTIYRWVQEY
                     GKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGL"
BASE COUNT           92 a           39 c           53 g           82 t
ORIGIN      
        1 gcaggatgtg attattgtag ccgtgggcta ctatcttcgt tataacctta gctatcgtga
       61 agttcaagaa atcttatatg atcgtggcat taacgtttct catacgacga tttatcgttg
      121 ggtgcaagaa tatggcaaac tactctatca aatttggaaa aagaaaaata aaaaatcctt
      181 ttattcatgg aaaatggatg aaacgtacat caaaattaaa ggaaaatggc attatttgta
      241 tcgagccatc gatgcagatg gtttaa
//
LOCUS       DACBYO010000307          262 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.322, whole genome shotgun sequence.
ACCESSION   DACBYO010000307 DACBYO010000000
VERSION     DACBYO010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.322"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            complement(89..>262)
                     /locus_tag="IVD26_003134"
     CDS             complement(89..>262)
                     /locus_tag="IVD26_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAP6081008.1"
                     /translation="GGLNWLLVGLFELDLVAMIAGGSTTIFAKIIYIVVGICAIYCLK
                     FFPMITRKVDERY"
BASE COUNT          103 a           52 c           36 g           71 t
ORIGIN      
        1 aagaaaagca gatggtttaa aatgaaaaaa ccttcccaat aaagggaagg ttcatgaaga
       61 taataacttt tttaataatt atagctttct aatatctttc atcaactttt ctagtaatca
      121 ttgggaaaaa tttcaagcag tagatcgcac aaatacctac gacgatataa atgatcttcg
      181 caaaaatagt tgttgaacca ccagcaatca tagctactaa atcaagttcg aacaagccta
      241 ccaacagcca gttcaaccct cc
//
LOCUS       DACBYO010000308          239 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.323, whole genome shotgun sequence.
ACCESSION   DACBYO010000308 DACBYO010000000
VERSION     DACBYO010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.323"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            16..222
                     /locus_tag="IVD26_003135"
     CDS             16..222
                     /locus_tag="IVD26_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP6081009.1"
                     /translation="MNLIYDEIAIDPYKGEQKTGDLSGIWSSGFKYAGTTYRVAYEII
                     ENKVIPVLLCGTHENFYEQLKKLI"
BASE COUNT           84 a           24 c           51 g           80 t
ORIGIN      
        1 ttgaaagaaa aatttttgaa tttaatttat gatgaaattg cgattgatcc atataagggt
       61 gaacaaaaaa ctggggattt atcaggtatt tggtctagtg ggttcaaata tgcgggcaca
      121 acatatagag tagcttacga gattatagaa aacaaggtta ttccagtatt gttatgtgga
      181 acgcatgaaa acttttatga acagttgaaa aaattaatct agtgatttgt tgtcgttct
//
LOCUS       DACBYO010000309          233 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.denovo.324, whole genome shotgun sequence.
ACCESSION   DACBYO010000309 DACBYO010000000
VERSION     DACBYO010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.denovo.324"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
BASE COUNT           79 a           35 c           45 g           74 t
ORIGIN      
        1 tgagaaaaag catggaatgc gctgcatcag gtatcgaggc ttagaaaaaa atcaggtgca
       61 tacgatgctt gtttttgccg aaatgagtct gaaaaaattg gtcacttagc agtgggagca
      121 tatgtcttca tattttttat tatacaaaaa tagacaaaag tatcagtcta cactcttagt
      181 aaagaggaaa ctgatacttt tgtctacagt atgatatttc ttacatctac ttt
//
LOCUS       DACBYO010000310         4343 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.149, whole genome shotgun sequence.
ACCESSION   DACBYO010000310 DACBYO010000000
VERSION     DACBYO010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.149"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..199
                     /locus_tag="IVD26_003136"
     CDS             <1..199
                     /locus_tag="IVD26_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP6081010.1"
                     /translation="VALTEKAQKKIEHCEMDHKDTGSVLSPAFSDVEMKQFLTLLDKL
                     NTQLCNITTETKEVNNNGTKK"
     gene            183..812
                     /locus_tag="IVD26_003137"
     CDS             183..812
                     /locus_tag="IVD26_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP6081011.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            1166..2644
                     /gene="msr"
                     /locus_tag="IVD26_003138"
     CDS             1166..2644
                     /gene="msr"
                     /locus_tag="IVD26_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAP6081012.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            2691..3137
                     /locus_tag="IVD26_003139"
     CDS             2691..3137
                     /locus_tag="IVD26_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAP6081013.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(3336..3851)
                     /locus_tag="IVD26_003140"
     CDS             complement(3336..3851)
                     /locus_tag="IVD26_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP6081014.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            3968..>4343
                     /locus_tag="IVD26_003141"
     CDS             3968..>4343
                     /locus_tag="IVD26_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP6081015.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNA"
BASE COUNT         1401 a          731 c          921 g         1290 t
ORIGIN      
        1 tgtagcgcta acagaaaaag cccagaagaa aatcgagcat tgtgaaatgg accataaaga
       61 tacaggttcc gtgctatccc cggctttcag cgatgtagaa atgaaacaat ttctaacact
      121 tttagataaa ttgaataccc aactttgcaa tataacaaca gaaacgaaag aggttaataa
      181 taatggaaca aaaaaatgat ttttcaacaa ttatgactgg tagaagatcc gttcgcgtat
      241 atgatgaaac atacaaaatc ccacacgaag aaatgctgga aatgatcaaa gaagcgacga
      301 ctgcaccttc ttctgtcaat atgcaaccat ggcgctttgt ggtcgctgaa agcgaggaag
      361 caaaagaaat cttgcgtcct ttgatccgtt tcaatacgag acaaaatgat acttcttctg
      421 caatggtcat gatttttggc gatatgcaat gttacgaata tggcgaagaa atctataacc
      481 aagcttacga atcagggaag atgccaaaag aagtcagaga tcaacaatta gctgcgatca
      541 ttccttatta caagagtttt tcaagagaag aaatgaacga tgtagtcaaa gtcgattcta
      601 gcttagcggc tatgcaattc atgttagttg cgcgtgatca tggctatgaa acaaatccaa
      661 ttggtggagt cgaagcagat cagttggcag aggcatttgg tttggataaa gaccgttatg
      721 ttccagttat tattttatca ataggaaaag cggtagaaga aggttacgag tctgttcgtt
      781 tagcaccaga aaagatcact acgttcgaat aaaaggtttt cagttactat tcagtagcta
      841 ttgctttttt tgaatcgtgt gtggtaacct aataaaaaag gaggtcggaa aaatgactgc
      901 atcgatgaaa ttacgtttcg aacttttgaa taacaactaa ataaattcaa aagacatgta
      961 taaacaacaa tttcatggat ggagtatgtc cattttttcg aacgacagta gaataggtga
     1021 aagctatgac agatttggtg atttagtcat agttatttcg ttcagagtag gaaaagatgt
     1081 gatgcagttt ttttgcaaac agatttttct gctctttttt agtatcgata attgttgttt
     1141 tacatgaaat aggagtgtaa aacatatgga aaatttagca gtaaatataa caaatctaca
     1201 agtcagcttt ggcaaccagc tagaactatc tattgattct cttcgtgtct atcagcaaga
     1261 tcgtataggg atcataggag aaaatggtgt cggtaaatcg actttgctca aactaatagc
     1321 cggtgaactt tttcccgatc atgggaaaat ccaaacagag atcaccttca actacctgcc
     1381 tcaattaacc tatctcgctg aagcaaagga cctaaatttg gaattagcca gtcatttcca
     1441 gttaagactg gaagaaactt cagagcggaa atggagcgga ggggaagaac gaaagatcga
     1501 gttgatacgt cttctttctt cttatgaaca agggatgctt ctagacgagc caacaaccca
     1561 tctagataga aaaagtattg atcgactgat tgaagagctt cgttattatt atggtacgct
     1621 ggtttttgtt agtcatgatc gctattttct agatgagcta gcatcgaaaa tctgggaagt
     1681 aaaagacgga gaaatccgag agttttcggg gaattatagt gcctatctca ctcaaaagga
     1741 attggagaaa aagactcagc tacgagaagc agagtcgatc atgaaagaga aaaaacgatt
     1801 ggaaaaatcg atccaagaaa agaaaaaaca agcggaaaag ttggaaaaag tgtccagtaa
     1861 aaagaaaaag caacaaatca gaccggatcg gttgtcttcc tctaaacaaa aagacagtgt
     1921 acaaaaagcc atccaaaaga atgcgaaaac attagagaga agactccaaa aaataggaga
     1981 aacaaccaag ccgcagcaga tgaaacaaat ccgttttcca gtaccaaaat ctcttgaact
     2041 ccacagccgc tatcccatca tgggacaaaa tgtccaattg gaaagaagtg ggagaacatt
     2101 actggtaaat ggtgattttc agttttcttt aggtaaaaaa atcgcgattg tcggtgaaaa
     2161 tggttcaggt aagacaacct tattagaaca tatccgcaaa caaggagaag gaatccttct
     2221 ctctccgaaa gtaagctttc aagtatatca gcaaaagggt tatcaaatga catctgaaga
     2281 atccatcatt cgttttgtca tgagacaaac agagttttca gaatcgcttg tccgtagttt
     2341 gctgaatcac ttagggtttg ctcaggaaac tttgacgaaa ccgttatgta cattaagtgg
     2401 gggagaagcg acccgtctga cgattgcttt gctttttact aagccaagta atgtgttgct
     2461 gttagatgaa ccgactaatt ttattgatat ggcaacgatc gaagctttag agaagctaat
     2521 gcaaatatat ccgggaacga ttttgtttac ttctcatgat tcttactttg tcgagcgtac
     2581 ggctgatgaa gtttatgaaa taaaagggca gaaaataaaa aaagtactta cgagaaattt
     2641 ttaaatgtgc tacgatgatt ttcgtgacaa atttaaagga gtggtacaga ttgcctacaa
     2701 ataaaaaaga aggaataatt tttacaacaa tgatgtgttt tttgatggtc ttggggatga
     2761 gcgcgtataa tttatggctg catcaagatc ttcatttatc aagtttgttg attggtctag
     2821 tgcctggatt cgtggtggct ttcattttgg atgtcttcat catcggtgtg ctggcgaaaa
     2881 aaattgcctt taaactacca gtaaatccag aaagcaaggt ccaaatgatc ttaactattt
     2941 catgcttgat ggttttagga atggtgacat gtatgtcttt attcggtgtg atcatggaac
     3001 aaggaatacc tgatcaatta ttctctgctt atatgaatgc ttggaaaatg aatgtgattg
     3061 ccgctttacc gttgcagttg atcatcgttg gcccgctttc aagaagtgtg ctaaaagcaa
     3121 ttcaaagtaa tgaatgatgg aacactgtta tttgaaaaaa ggccttggca tgctttttgt
     3181 catagtctct tgaatgcagt tctagaaaaa tagtgatccg aacgataggt tttggcctgt
     3241 cgttcggatc gctttttctt ttccaactgt attgctcttt tattgaagat aatttgctct
     3301 tcaatagata tttctagaaa ggttctgttt atcccttact caaaaaactg ctgcatttgt
     3361 tctcttactt gctgacacca ttggagttcc tgctgacaaa gcataattct gcgctggatc
     3421 acaacataac gtccaaattc ttgtttcttg tctagcgaga ggtcattcaa ttttttttga
     3481 tttttttgca tgattttgtt cagctgttgt tctctagtga atagcagtcc agtagctgtt
     3541 gttttatcga gcgtcgaaaa agcatagatt tttgctagaa attcatcttt ttgcgtagga
     3601 gcgggagttt cctctttgat ccattcctct acaagagcac gtccttcatc agtcaagtgg
     3661 tagatctttt tttgagagtg ctcgtctttg tccaaaacgg tcacataacc ctgctggtct
     3721 aacttggcaa gcgttgtata gatctgactg tgatgggctt cccaaaaaat tgtgatcagc
     3781 tgcttcaatt catacccaga acgtggtttg gataaaagca cgcataataa tatataggct
     3841 aaagtattca taaaaatcct acctctcgtc ttattttctt tattatatca cagtaaagtt
     3901 tccacgtttt acatgtgcat atttacatgt aaaataaatc atgtatgatg ctaatagaga
     3961 gaaagggatg gaaatattgg agaatcaaat agatatacaa gaacaaacaa atgaagaaac
     4021 aaaggggaaa agttcagcgc tagttgtagc agctacctgt atgatcgctt ttatgggagt
     4081 gggtctagta gacccaatct taaaaacgat tgctgcacag ttaaacgcta cgccagctga
     4141 aacgaccctg ttatttacta gttacatgtt agtcactggt gtggtgatgc tatttacagg
     4201 tttcttatct agtcggatcg gtttgaaaaa aacattgatg acaggattgt ttatcatcgt
     4261 tgtattcgct ggtcttggcg gattatctgg gaatatcgga atgctgattg ggttacgtgc
     4321 cggctggggt gtcgggaatg ctt
//
LOCUS       DACBYO010000311         4173 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.152, whole genome shotgun sequence.
ACCESSION   DACBYO010000311 DACBYO010000000
VERSION     DACBYO010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.152"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            3..188
                     /locus_tag="IVD26_003142"
     CDS             3..188
                     /locus_tag="IVD26_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005611413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6081016.1"
                     /translation="MNISVSELARRIGQTPQNFNKKLQRETVTLDELKAIADVLGVKF
                     VQAFILPDGEEIKISNE"
     gene            203..1072
                     /locus_tag="IVD26_003143"
     CDS             203..1072
                     /locus_tag="IVD26_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAP6081017.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            1053..1787
                     /locus_tag="IVD26_003144"
     CDS             1053..1787
                     /locus_tag="IVD26_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP6081018.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            1820..2728
                     /locus_tag="IVD26_003145"
     CDS             1820..2728
                     /locus_tag="IVD26_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAP6081019.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            2725..3267
                     /gene="sat4"
                     /locus_tag="IVD26_003146"
     CDS             2725..3267
                     /gene="sat4"
                     /locus_tag="IVD26_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAP6081020.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            3360..4154
                     /locus_tag="IVD26_003147"
                     /note="aph(3')-IIIa"
     CDS             3360..4154
                     /locus_tag="IVD26_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAP6081021.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         1424 a          623 c          962 g         1164 t
ORIGIN      
        1 aaatgaatat aagtgtttcc gaacttgcta gacgtattgg ccagactcca cagaatttca
       61 ataaaaaatt acaacgagaa acagtaacct tggatgagtt gaaggccatt gctgatgtgc
      121 taggtgtcaa gtttgtgcag gcatttattt taccagatgg agaagaaata aaaatatcta
      181 acgaataaag gaggatgttt atatggtagg taatgttatt caaatagtaa cagagaaatt
      241 atcatctttg ccttttatag aaggcatcgt attagggggc tcacgtgcaa gaggcaccca
      301 tacagaaaat tctgatatag atatcggaat ctattacaat tcagactcat ttgacctgac
      361 agcgattaat caaattgcta cagagttgga tgatgagaat agaaacaacc ttgttgtacc
      421 tcccggagcg tggggtgatt gggttaatgg cggtggatgg ttagttataa acgggtgtca
      481 tgttgacttg atattacgtg atataaaacg ggtggaacaa ataatcaaag atacggagca
      541 aggaattgtt actgccaatt atcagaccgg gcatccccat ggttatataa gtgctatgta
      601 tcgtggagaa ttagcgatta gtaaaatact atatgctaag aacgaaagct tatgcgaatt
      661 aaaaaagcag gcagaaattt accctactgc tctaaagaaa agcttgatga acttttttat
      721 atttgaagct gaattctctt taatgtttgt aaaagcaaat gcgggggcag aggataaata
      781 ttatattgca ggccatgttt ttcgtattat ttcatgctta aatcaagtac tatttgcatg
      841 taataatgct tattgcatta acgaaaagaa agctataaaa ctgcttgaaa cttttgaata
      901 taaacctgaa aaatatgccg aaagagttaa tcatattttt gaagtactcg gtctttctct
      961 ttttgaatgc tacgacatga ccgagaaact ttataaagaa gtgaatgaaa ttgtatcgga
     1021 gataaataac tttttaaacg aggagagttc agatgaaaga aaacaaatat gatgataata
     1081 tattttttca aaaatacagt caaatgagtc gctcgcagaa aggactggct ggtgcgggag
     1141 aatgggagac tttgaaaaag atgctacctg attttaaggg taagcgtgtg cttgatttag
     1201 gatgcggcta tggatggcac tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag
     1261 gtgttgatat ttctcataaa atgctcgaag tagcaaaagg aaaaacccat tttccacaga
     1321 ttgaatatga atgctgtgcc atagaagatg tggatttccc agaggagagc tttgatgtaa
     1381 tactaagttc gcttgcgttt cattatgtag cagactatga gaatttaata aaaaagatat
     1441 ataggatgct gaaggctggt ggcaatttag tttttacagt tgaacatcct gtttttactg
     1501 ctcatggaac acaagactgg tattataacg aaaaaggaga aatactgcat ttcccggtgg
     1561 acaattatta ttatgagggc aaacggacag ctatgttttt ggaagaaaag gttacaaaat
     1621 atcatagaac actgaccaca tatctaaata cactgctttc aaatagtttt ataataaatc
     1681 agattgtgga gccacagccg ccagagaaca tgatggatat tccggggatg gcggatgaaa
     1741 tgcgacgccc aatgatgctg attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa
     1801 ataaacgagg agtatgtaaa tgagatcaga aaaagaaatg atggatttag tactttcttt
     1861 agcagaacag gatgaacgta ttcgaattgt gacccttgag gggtcacgcg caaatattaa
     1921 tatacctaaa gatgaatttc aggattatga tattacatat tttgtaagtg atatagaacc
     1981 gtttatatct aatgatgact ggcttaatca atttgggaat ataataatga tgcaaaagcc
     2041 ggaggatatg gaattattcc cacctgaaga aaagggattt tcctatctta tgctatttga
     2101 tgattacaat aaaattgatc ttaccttatt gcccttggaa gagttagata attacctaaa
     2161 gggcgataaa ttaataaagg ttctaattga taaagattgt agaattaaaa gggacatagt
     2221 tccgactgat atagattatc atgtaagaaa gccaagcgca agggagtatg atgattgctg
     2281 caatgaattt tggaatgtaa caccttatgt tattaaagga ttgtgccgta aggaaatttt
     2341 atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg
     2401 gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga
     2461 aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta
     2521 tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga
     2581 ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac
     2641 cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc
     2701 tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat
     2761 atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac
     2821 gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac
     2881 gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag
     2941 ataatatatc tttactacca agacgataaa tgcgtcggaa aagttaaact gcgaaaaaat
     3001 tggaaccggt acgcttatat agaagatatc gccgtatgta aggatttcag ggggcaaggc
     3061 ataggcagcg cgcttatcaa tatatctata gaatgggcaa agcataaaaa cttgcatgga
     3121 ctaatgcttg aaacccagga caataacctt atagcttgta aattctatca taattgtggt
     3181 ttcaaaatcg gctccgtcga tactatgtta tacgccaact ttgaaaacaa ctttgaaaaa
     3241 gctgttttct ggtatttaag gttttagaat gcaaggaaca gtgaattgga gttcgtcttg
     3301 ttataattag cttcttgggg tatctttaaa tactgtagaa aagaggaagg aaataataaa
     3361 tggctaaaat gagaatatca ccggaattga aaaaactgat cgaaaaatac cgctgcgtaa
     3421 aagatacgga aggaatgtct cctgctaagg tatataagct ggtgggagaa aatgaaaacc
     3481 tatatttaaa aatgacggac agccggtata aagggaccac ctatgatgtg gaacgggaaa
     3541 aggacatgat gctatggctg gaaggaaagc tgcctgttcc aaaggtcctg cactttgaac
     3601 ggcatgatgg ctggagcaat ctgctcatga gtgaggccga tggcgtcctt tgctcggaag
     3661 agtatgaaga tgaacaaagc cctgaaaaga ttatcgagct gtatgcggag tgcatcaggc
     3721 tctttcactc catcgacata tcggattgtc cctatacgaa tagcttagac agccgcttag
     3781 ccgaattgga ttacttactg aataacgatc tggccgatgt ggattgcgaa aactgggaag
     3841 aagacactcc atttaaagat ccgcgcgagc tgtatgattt tttaaagacg gaaaagcccg
     3901 aagaggaact tgtcttttcc cacggcgacc tgggagacag caacatcttt gtgaaagatg
     3961 gcaaagtaag tggctttatt gatcttggga gaagcggcag ggcggacaag tggtatgaca
     4021 ttgccttctg cgtccggtcg atcagggagg atatcgggga agaacagtat gtcgagctat
     4081 tttttgactt actggggatc aagcctgatt gggagaaaat aaaatattat attttactgg
     4141 atgaattgtt ttagtaccta gatttagatg tct
//
LOCUS       DACBYO010000312         3498 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.170, whole genome shotgun sequence.
ACCESSION   DACBYO010000312 DACBYO010000000
VERSION     DACBYO010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.170"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            6..95
                     /locus_tag="IVD26_003148"
                     /pseudo
     CDS             6..95
                     /locus_tag="IVD26_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646598.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            355..2274
                     /gene="tet(M)"
                     /locus_tag="IVD26_003149"
     CDS             355..2274
                     /gene="tet(M)"
                     /locus_tag="IVD26_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAP6081022.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2393..2560
                     /locus_tag="IVD26_003150"
     CDS             2393..2560
                     /locus_tag="IVD26_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP6081023.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(2620..2973)
                     /locus_tag="IVD26_003151"
     CDS             complement(2620..2973)
                     /locus_tag="IVD26_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP6081024.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
BASE COUNT         1188 a          536 c          676 g         1098 t
ORIGIN      
        1 tctgatttgt ggtaaatcag gcaaaggcaa cgcaggtatc tcaatttgat ttggtacttg
       61 aaaagaacgg gagtaattgg aagattatag aataacaaat attggtacat tattacagct
      121 attttgtaat cacgtactct ctttgataaa aaattggaga ttcctttaca aatatgctct
      181 tacgtgctat tatttaagta tctatttaaa aggagttaat aaatatgcgg caaggtattc
      241 ttaaataaac tgtcaatttg atagtgggaa caaataattg gatgtccttt tttaggaggg
      301 cttagttttt tgtacccata tgcccttttg ggtttttgaa tggaggaaaa tcacatgaaa
      361 attattaata ttggagtttt agctcatgtt gatgcaggaa aaactacctt aacagaaagc
      421 ttattatata acagtggagc gattacagaa ttaggaagcg tggacaaagg tacaacgagg
      481 acggataata cgcttttaga acgtcagaga ggaattacaa ttcagacagg aataacctct
      541 tttcagtggg aaaatacgaa ggtgaacatc atagacacgc caggacatat ggatttctta
      601 gcagaagtat atcgttcatt atcagtttta gatggggcaa ttctactgat ttctgcaaaa
      661 gatggcgtac aagcacaaac tcgtatatta tttcatgcac ttaggaaaat ggggattccc
      721 acaatctttt ttatcaataa gattgaccaa aatggaattg atttatcaac ggtttatcag
      781 gatattaaag agaaactttc tgccgaaatt gtaatcaaac agaaggtaga actgtatcct
      841 aatatgtgtg tgacgaactt taccgaatct gaacaatggg atacggtaat agagggaaac
      901 gatgaccttt tagagaaata tatgtccggt aaatcattag aagcattgga actcgaacaa
      961 gaggaaagca taagatttca gaattgttct ctgttccctc tttatcatgg aagtgcaaaa
     1021 agtaatatag ggattgataa ccttatagaa gttattacta ataaatttta ttcatcaaca
     1081 catcgaggtc cgtctgaact ttgcggaaat gttttcaaaa ttgaatatac aaaaaaaaga
     1141 caacgtcttg catatatacg cctttatagt ggagtactac atttacgaga ttcggttaga
     1201 gtatcagaaa aagaaaaaat aaaagttaca gaaatgtata cttcaataaa tggtgaatta
     1261 tgtaagattg atagagctta ttctggagaa attgttattt tgcaaaatga gtttttgaag
     1321 ttaaatagtg ttcttggaga tacaaaacta ttgccacaga gaaaaaagat tgaaaatccg
     1381 caccctctac tacaaacaac tgttgaaccg agtaaacctg aacagagaga aatgttgctt
     1441 gatgcccttt tggaaatctc agatagtgat ccgcttctac gatattacgt ggattctacg
     1501 acacatgaaa ttatactttc tttcttaggg aaagtacaaa tggaagtgat tagtgcactg
     1561 ttgcaagaaa agtatcatgt ggagatagaa ctaaaagagc ctacagtcat ttatatggag
     1621 agaccgttaa aaaatgcaga atataccatt cacatcgaag tgccgccaaa tcctttctgg
     1681 gcttccattg gtttatctgt atcaccgctt ccgttgggaa gtggaatgca gtatgagagc
     1741 tcggtttctc ttggatactt aaatcaatcg tttcaaaatg cagttatgga ggggatacgc
     1801 tatggctgtg aacaaggatt gtatggttgg aatgtgacgg actgtaaaat ctgttttaag
     1861 tatggcttat actatagccc tgttagtacc ccagcagatt ttcggatgct tgctcctatt
     1921 gtattggaac aagtcttaaa aaaagctgga acagaattgt tagagccata tcttagtttt
     1981 aaaatttatg cgccacagga atatctttca cgagcataca acgatgctcc taaatattgt
     2041 gcgaacatcg tagacactca attgaaaaat aatgaggtca ttcttagtgg agaaatccct
     2101 gctcggtgta ttcaagaata tcgtagtgat ttaactttct ttacaaatgg acgtagtgtt
     2161 tgtttaacag agttaaaagg gtaccatgtt actaccggtg aacctgtttg ccagccccgt
     2221 cgtccaaata gtcggataga taaagtacga tatatgttca ataaaataac ttagtgtatt
     2281 ttatgttgtt atataaatat ggtttcttgt taaataagat gaaatatttt ttaataaaga
     2341 tttgaattaa agtgtaaagg aggagatagt tattataaac tacaagtgga tattgtgtcc
     2401 tgtatgtgga aataaaacac gattaaagat aagggaagat actgaattaa aaaaattccc
     2461 cctctattgt ccgaaatgca gacaagaaaa tttaattgaa ataaagcagt tcaaagtaac
     2521 tgtgattaca gagccagacg caaagacgca gagccgataa aatgagatta atacaatctc
     2581 attttatcgg ctctttccgt tatgtatgga ttcttttaat tagtcttcga tgtttcttgc
     2641 ttcgttgata ccgctggcta aagattccat taaggatagt tctttgtctg taaagctatc
     2701 catgtatttc tctatctgta atcgtcgggt gctttttacc aagttattag caggtaagaa
     2761 aaattcatca acggaaacat gaagtaacga tacaaggtca taaagaactt gtatgctggg
     2821 gtgttgccct ttattttcaa tattagttaa gtaccgtggg tcaatttcaa tcaatgctcc
     2881 cacttgttca cgagttaaac ctcgtttcaa tcgagcttct ttaatggcta aaccaaaggc
     2941 tctaaaatca tatttatctt cttttttacg catagtagac cacctctata cattttattg
     3001 ttcctactga attaaaaaca ggtatagaaa aacgtgttat atggtttata ggtttatatt
     3061 taataaaaag cactactaaa cgccaataaa aaaaaccgtt atatggtagt gctatttacg
     3121 ctgttaaaat attgtatatt acttccaaat ggcggtttgt tggaggtcaa cgtcgccatg
     3181 aagtacatca tatacaataa atttccttac attgggttct tgtcaaaaaa agtcgtctat
     3241 ctgcaataga taagtacgtc caccaatgtg gttttataaa tcatatagat agaataacag
     3301 aagcatgtaa acagagaaat aaatctgttt atatgctttt ttggctattc agaacttttt
     3361 tacaaagttt atttatcagt aatgcaacaa atcccccttt cacattggga ctaagagtga
     3421 aaggagataa acgagcaagg ctcacttcct ttcctagaca gaaagggggt gagattatga
     3481 ggacatcttc tttcgagc
//
LOCUS       DACBYO010000313         2771 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.187, whole genome shotgun sequence.
ACCESSION   DACBYO010000313 DACBYO010000000
VERSION     DACBYO010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.187"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            110..193
                     /locus_tag="IVD26_003152"
     CDS             110..193
                     /locus_tag="IVD26_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAP6081025.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="IVD26_003153"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="IVD26_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAP6081026.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1318..2181)
                     /locus_tag="IVD26_003154"
     CDS             complement(1318..2181)
                     /locus_tag="IVD26_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAP6081027.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2183..2455)
                     /locus_tag="IVD26_003155"
     CDS             complement(2183..2455)
                     /locus_tag="IVD26_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP6081028.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2472..2681)
                     /locus_tag="IVD26_003156"
     CDS             complement(2472..2681)
                     /locus_tag="IVD26_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAP6081029.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          851 a          487 c          443 g          990 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa attttgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac cgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat agatgtaatc
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttgtaaattt
     1081 ggaaagttac acgttactaa agggaatgta gataaattat taggtatagg gcacctctaa
     1141 taactaccaa ttaattcacc tcaaaatgaa attagaaaaa aacagcgaaa tttttaaatc
     1201 tatttcttat cgatacaaat tcctcgtagg cgctcgggac cccaacatga ggaaatgttt
     1261 ttataaaaaa agagtagtta ccgttttttg gtaactactc ttttcctttt ttaaggttta
     1321 aatacctgga agtttaggtg ttttgggtat tggtggtgta ggtagctgca agctttccat
     1381 tttttgttga attgctttaa attcaggggt ttcttggtgt tgattttgaa ccattttttg
     1441 ctctattctc tccaaagtcg gttgaatttc tttccctgat actttacgat ttaattctct
     1501 ttctaaggtc tctttcggac taatggaagg cgtttctaag cttgaataga gtttcactcc
     1561 ttctctattg taaagcctta tatcgctaaa taagcccgtt ttatgaaggg tttctaaatt
     1621 ggtcggtaag tttttgacaa caatatcatg cgcttgtttt ggtgttgccc tagctgtcat
     1681 tggatcatct gcatacatgg tttcatatcg ttcaatcgtt cctaagtatg attcaatttt
     1741 cggtactgcc atgacgtata tttttgtttc ataaccttta gattgaagca ttgtggctgt
     1801 ttgaatggga acgtctgttg ttcgtcctgt tccttcaatc actaaattat agccttgatc
     1861 gcttaaacgg ctaataagtg cttctgtcat gcgattcgaa taaggggtaa cgtgttttac
     1921 tacgtctttt tcatagagtt tcactaattc gtcaaaattt gggtgctgtt gtttaaaggt
     1981 atcattatca atgacaataa cattcccttg tgtttcttca aaaattgctg atcgcaaact
     2041 ggttttccct gaccctggtt gcccaccaag taaaaaagcg gttggcgatt caaccgctag
     2101 tctattttta gttagtcgtt caacattctt ttctaaacga tcttcaaatt gcttttcggt
     2161 gaagtcagta atattcgcca tgttaagcca ctttctcttt attcaaaatt tgttttgaat
     2221 attgattcat tgaccgccaa tactcatgaa tagcttgtaa ttcttcaaat ggttgttgaa
     2281 ataaatcaac ttcttgtgcc acttctaatt gatttaaaag attcacttct agtaaacgag
     2341 tatttttagt atctagttca tgattcaaaa cataatttaa tacccgatta taaacacttg
     2401 ccgataactc attaatgatt tcaatttcaa atgttttttc atacgtaact gccatttcat
     2461 tttcactcct tttaaagttt gtcaggtaaa tatttccgta tatattcttc taaggcttga
     2521 tccataactt cttttacgtt tccgccattc tttgctgttt cgatttttat gatatggtgc
     2581 aagtcggcac gaacacgaac cgtcttatcc cccattatat ctttttttgc gctgattggc
     2641 gtatcatttc gttttgcttt ctgtgcgcct aaatttccca cgatcgctca cttctttcta
     2701 tttcttctta ctatttattt tatcatcacc tatcacaaat cacaagtgat ttgtgattaa
     2761 tcacttgtga t
//
LOCUS       DACBYO010000314         2743 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.188, whole genome shotgun sequence.
ACCESSION   DACBYO010000314 DACBYO010000000
VERSION     DACBYO010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.188"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            229..447
                     /locus_tag="IVD26_003157"
     CDS             229..447
                     /locus_tag="IVD26_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP6081030.1"
                     /translation="MRQERPEGVHTGPACVKSHTARCIRKKEAAHFAEAWGVPNKQNE
                     NAAGGQVVDQNIRKGYSDPLLASIIGMF"
     gene            660..1319
                     /locus_tag="IVD26_003158"
     CDS             660..1319
                     /locus_tag="IVD26_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HAP6081031.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            1322..2665
                     /gene="vanS"
                     /locus_tag="IVD26_003159"
     CDS             1322..2665
                     /gene="vanS"
                     /locus_tag="IVD26_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAP6081032.1"
                     /translation="MERKGIFIKVFSYTIIALLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAAFHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQAQSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
BASE COUNT          798 a          545 c          688 g          712 t
ORIGIN      
        1 gtctccagac attggataac tgctggtcta atgcgccttt gagtatgggg tgattgattt
       61 taataccggg gaggtacggc tttttgagga aaatattctg ggatttacat ttggcgatta
      121 ttacatttcc tgtaactgca aggacacgga tgatgaagat atgaggaata tagacttgct
      181 gattttctac tgtcttgaac ggtattagga ctgaatctgc tgcgcggagt gcggcaagag
      241 cgaccggagg gagtacacac aggccctgcc tgtgtgaaaa gccataccgc aaggtgcatt
      301 cgcaaaaaag aggccgcgca ttttgctgag gcttggggtg tccccaacaa gcaaaacgag
      361 aacgccgcag gcgggcaagt ggtggatcag aatatccgta aaggatattc tgatccattg
      421 cttgccagta ttatcgggat gttttgacaa ccgctgtaat cgaaacatcc caaacattaa
      481 gaaggtgtta attattatta tcttgattta attcgtttaa accaataata tagatacata
      541 caccatgaaa agaagcgagt atcccaatga cggatgatta aaatccgaaa agaaatcgct
      601 ttgaaactac agggaaacta cagactgtta tgttatcttc ttaaaatgga gggattttta
      661 tgtcgatacg aattctactt gtcgaggatg atgatcatat ctgtaataca gtaagggcgt
      721 ttctggctga ggcaggatat caggtggatg cctgcacaga tggaaatgag gcatacacca
      781 agttttacga aaacacttat caactggtta ttcttgatat tatgctgccc ggtatgaacg
      841 ggcatgaact tttgcgtgaa tttcgtgcga aaaatgatac tcccattctg atgatgacag
      901 ccctgtcgga tgacgaaaac caaatccggg cgtttgatgc agaggcagac gactatgtaa
      961 caaagccatt caagatgcag attttactaa agcgggtgga agccctgctg cggcgcagcg
     1021 gtgcgctggc aaaggaaatc cgtgtcggca ggctgacact tctgccggag gatttcacgg
     1081 tactttgtga cggtacagag ctgcccctga cacgaaaaga atttgaaatc cttttgctgc
     1141 tggtgcagaa caaaggcaga accttaacgc atgaaatcat tttgtcacgt atatggggat
     1201 atgactttga gggtgatggc agcacagtcc acactcatat caaaaatttg cgggccaagc
     1261 tgccggaaaa tatcatcaaa accattcgcg gtgtaggata ccgattggag gaatcataat
     1321 aatggaaaga aaagggattt tcattaaggt tttttcctat acgatcattg ccctgctact
     1381 gcttgtcggt gtaacagcaa cactgtttgc acagcaattt gtgtcttatt tcagagtgat
     1441 ggaattacag caaacagtaa aatcctatca gccattggtg gaactgattc agaatagcga
     1501 taggcttgat attcaagagg tggcagggct gtttcactac aataaccaat cctttgagtt
     1561 ttatattgaa gataaagagg gaagcgtact ctatgccaca ccaaatgcca atacatcaaa
     1621 tagttttaga cccgactttc tttatgtggt acatagagat gataatattt cgattgttgc
     1681 tcaaagcaag gcaggtgtgg gattgcttta tcaagggctg acaattcggg gaattgttat
     1741 gattgcgata atggttgtat tcagcctttt atgcgcgtat atctttgcgc ggcaaatgac
     1801 aacgccgatc aaagccttag cggacagtgc gaataaaatg gcaaacctga aagatgtacc
     1861 gccgccgctg gagcgaaagg atgagcttgg cgcactggct catgatatgc attccatgta
     1921 tgtcaggctg aaagaaacca tcgcaaggct ggaggatgaa atcgcaaggg aacatgagtt
     1981 ggaggaaaca cagcgatatt tctttgcggc agcttttcat gagctaaaaa cgcccatcgc
     2041 ggctacaagc gttctgttgg agggaatgct tgaaaatatc ggtgactaca aagatcattc
     2101 taagtatctg cgcgaatgca tcaaaatgat ggataggcag ggcaaaatca tttccgaaat
     2161 actggagctt gtcagcctga atgatgggag aatcgtaccc atagctgaac cgttggacat
     2221 agggcgcacg gttgccgagt tgctgcccga ttttcaaacc ttggcagagg caaacaacca
     2281 gcggttcgtc acagatattc cagccgggca aattgtcctg tccgatccga ggctgctcca
     2341 aaaggcacta tccaatgtca tattgaatgc agttcagaac acgccgcagg gaggcgaggt
     2401 acggatatgg agtgagcctg gtgctgaaaa atgccgcctt tttgttttga acatgggcgt
     2461 tcacattgat gatactgcgc ttccaaggct gttcacccca ttctatcgca ttgatcaggc
     2521 gcaaagcaga aaaagtgggc gaagcggttt aggacttgcc atcgtacaaa aaacgctgga
     2581 tgccatgagc ctccagtatg cgctggaaaa cacctcggat ggcgttttgt tctggctgga
     2641 tttaccgctc acatcaacat tgtaaatatt taaaacttaa atgattttga ccgacaggta
     2701 taaccggctc tttgtcaata aggactgatg agttgtgcaa aat
//
LOCUS       DACBYO010000315         2664 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.191, whole genome shotgun sequence.
ACCESSION   DACBYO010000315 DACBYO010000000
VERSION     DACBYO010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.191"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            322..1014
                     /locus_tag="IVD26_003160"
     CDS             322..1014
                     /locus_tag="IVD26_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP6081033.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1341..1838
                     /gene="dfrG"
                     /locus_tag="IVD26_003161"
     CDS             1341..1838
                     /gene="dfrG"
                     /locus_tag="IVD26_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAP6081034.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1910..>2664)
                     /locus_tag="IVD26_003162"
     CDS             complement(1910..>2664)
                     /locus_tag="IVD26_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAP6081035.1"
                     /translation="PYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRL
                     SDAHHFICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTS
                     HQFHEEAISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNV
                     NDHSTNSFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCR
                     PFKSADKKVLTPAQRLGITDKQFDWKDIIYFK"
BASE COUNT          998 a          372 c          476 g          818 t
ORIGIN      
        1 tttcataggt aaaagaagca tgacaattta tgacaaatcc gcgttttttg taataaatac
       61 agtaatctat gaaatgaaaa gggttacgtt taataaaact tgcttttttg tttttgttca
      121 ccataaatat ttatttaaga aagtattaac ctgcattttt ctctataaaa aagatttttt
      181 aaatagataa aaaaggagga ttaaatgagt atttgatagt atttatatta aaattacata
      241 tgtaatttaa aaacgcttga cattgtgttt gagatcactt acttttagca tgtaaaagta
      301 ttggattaag gagctatgca aatgaaaaag aaatttatta ctggtgggat tgtcgttgca
      361 tttctatgtc taattggcta cacaggcacg cggtacgcaa atgaaattat tttgtggggt
      421 ggagagacag atattgatac aatcaatgag aatctgacac agcttgatca tacattgaca
      481 gataaagagc aagcgattac agatcttacc gctcgactag cacaaaaaga acagacattg
      541 caagattcaa aggcagatgt ccaagaatac caaacaaaag taaatgaatt agaaaaccaa
      601 aaaaatcaat cggcagcaga aaaacaaaac ttagaaagtc aattagtcag caaggatgca
      661 caactacaaa gcaaacaaaa tgaaatcaat gtcaaactag atgagatcaa ccaaaaaaat
      721 gatgaaatca atcatctgaa tgcagattgg acagcaagac tacaagaagc acaagcaaaa
      781 ctttcagaat tacaaaatac tgtaaatggt ttgaatcaac aaatcgcaac actgacacaa
      841 gaaaaaacaa atgtagaaac tcagttaaca gatacacaaa agaaattaga cgaagcaact
      901 gctgaaaact caagcttgaa acaatatatt caaaagttag aaaaagcaaa agatgaagtg
      961 gaagatacag ctgataaatc tcagcaaatt gttgaagaac atttgcgtaa ataatctttc
     1021 ttaacaagta aacctaaatt agtaaagaag caacagtaat ctatactaag tagttcagtt
     1081 ttggagtaca aaatgacaaa atgtacttca aaatggacta cttttttcat tttaacttac
     1141 ataccaaatt acatacaaaa tgatttataa aatgcaattg aaaatgataa ttgaatgaaa
     1201 atttgtgatt ttgtggtatt atgataatat aacttataga aaaaattgct tattcaacta
     1261 acgggcagga taatgagaaa aggttttttg atagaaataa gaaattagat ggtaaattag
     1321 ttaaaaaggc tgtgttataa atgaaagttt ctttgattgc tgcgatggat aagaatagag
     1381 tgattggcaa agagaatgac attccttgga ggattcccaa ggactgggaa tatgttaaaa
     1441 atactacaaa gggacatccg ataatattag gtaggaagaa ccttgaatca atcggaagag
     1501 ccttacctga cagaagaaat attattctga cgagagataa ggggtttacc tttaatggtt
     1561 gtgaaattgt tcattcaata gaagatgttt ttgagttatg taaaaacgaa gaagaaattt
     1621 ttattttcgg aggagaacag atttataatt tgtttttccc ttatgttgag aaaatgtaca
     1681 tcacaaaaat acatcatgaa ttcgaaggag atactttttt tccagaagtg aattatgagg
     1741 aatggaatga ggtatttgcc caaaaaggga taaagaatga taaaaatccg tataactact
     1801 attttcatgt atatgaaaga aaaaacttat tgagttaacg ggtgcgttaa ttgaagaaga
     1861 acagtaaaga taaagcacaa gagcttggga ttactccaag ctctttttgt catttgaaat
     1921 aaattatatc tttccaatca aattgtttat ctgtaatccc taatctttga gcaggtgtca
     1981 aaaccttttt atccgctgat ttaaaagggc gacaaaagtt gtagtaagtt cttagaattg
     2041 taatcgcaaa ttgagcatac ttcggattga agttagcgta aatatagctc ttcttatcac
     2101 cacgagctgt tgttaatggt ctttcaagag atgatatata acgtcttatc tgttgaataa
     2161 agctattggt cgaatggtca ttaacattta atagcatctt tgcgatttcg tttggttcca
     2221 gagcagataa atccgttcta caatcaactg aataaaatcc tttatcctta gtggctaatg
     2281 gatgtttgat agggttatcg gcatatttgc gatatctttc tccatcttta ctaatagcct
     2341 cttcgtggaa ttgatgactt gttagtaatt cagttagata atgagatgcc aaagtccgta
     2401 gaaactttgt tttgaatcct ctgatatctc cccaatcgag cagttctgct tttgcttgtc
     2461 cgaattcttt taagcattgt tttctgcttt tcgtcttgtt aacttggcaa ataaaatgat
     2521 gtgcatcgct caaccttaat tctttcgtga atactctata aaaggcgttt ctaatagaga
     2581 agtcatcatc actaatcatt cgccattcgt cggcattaac catttgttta attaaccaat
     2641 agtgagcagt tgtagtataa ggag
//
LOCUS       DACBYO010000316         2481 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.196, whole genome shotgun sequence.
ACCESSION   DACBYO010000316 DACBYO010000000
VERSION     DACBYO010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.196"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..472
                     /locus_tag="IVD26_003163"
     CDS             <1..472
                     /locus_tag="IVD26_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HAP6081036.1"
                     /translation="GFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRH
                     LIGQKQIGEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDC
                     SQKVLDHPFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            465..1493
                     /gene="vanB"
                     /locus_tag="IVD26_003164"
     CDS             465..1493
                     /gene="vanB"
                     /locus_tag="IVD26_003164"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HAP6081037.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGTFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            1499..2107
                     /locus_tag="IVD26_003165"
     CDS             1499..2107
                     /locus_tag="IVD26_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HAP6081038.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
BASE COUNT          671 a          522 c          669 g          619 t
ORIGIN      
        1 gggatttgga tgccatgtgc tggcctatga taacagccga aaaatggatg cagattatgt
       61 ccagcttgat gagcttctaa aaaacagcga tattgttacg ctccatgtgc cgctttgtgc
      121 ggatacccgc catctgatcg gtcagaagca aattggagag atgaagcaag gcgcattttt
      181 aatcaacacc gggcgcggag cgcttgtcga taccggggcg ctggtggagg cgttggaaag
      241 cggaaagctg ggtggtgcgg cactggatgt gttggagggc gaggatcagt ttgtttatac
      301 cgattgctcg cagaaagtgc ttgaccatcc ctttttgtcg cagcttttaa ggatgccgaa
      361 tgtgatcatc acaccccata cggcgtacta cactgagcgt gtgctgcagg atactacaga
      421 aaaaacaatc aggaattgtc tcaattttga aaggagttta cagcatgaat agaataaaag
      481 tcgcaatcat cttcggcggt tgctcggagg aacatgatgt gtcggtaaaa tccgcaatag
      541 aaattgctgc gaacattgat acggaaaaat tcgatccgca ctacatcgga attacaaaaa
      601 acggtgtatg gaagctatgc aagaagccat gtacggaatg ggaagccgac agtctccccg
      661 ccatactctc cccggatagg aaaacgcatg ggctgcttgt catgaaagaa agcgaatacg
      721 aaacacggcg tattgatgtg gctttcccgg ttttgcatgg caaatgcggg gaggatggtg
      781 cgatacaggg gctgtttgta ttgtctggta tcccctatgt gggctgtgat attcaaagct
      841 ccgcagcttg catggacaaa tcactggcct acattcttac aaaaaatgcg ggcatcgccg
      901 ttcccgaatt tcaaatgatt gataaaggtg acaagccgga ggcgggtgcg cttacctacc
      961 ctgtctttgt gaagccggca cggtcaggtt cgtcctttgg cgtaaccaaa gtaaacggta
     1021 cggaagaact taacgctgcg atagaagcgg caggacaata tgatggaaaa atcttaattg
     1081 agcaagcgat ttcgggctgt gaggtcgggt gtgcggtcat ggggaacgag gatgatttga
     1141 ttgtcggcga agtggatcaa atccggctga gccacggtac cttccgcatc catcaggaaa
     1201 acgagccgga aaaaggctca gaaaatgcga tgattacagt tcccgcagac attccggtcg
     1261 aggaacgaaa tcgggtgcag gaaacggcaa agaaagtata tcgggtgctt ggatgcagag
     1321 ggcttgcccg tgttgatctt tttttgcagg aggatggcgg catcgttcta aatgaggtca
     1381 ataccctgcc cggttttaca tcgtacagcc gctacccacg tatgatggcc gccgcaggaa
     1441 tcacgcttcc tgcactgatt gacagcctga ttacattggc gttaaagagg tgataagtat
     1501 ggaaaatggt tttttgtttt tagatgaaat gttgcatggc gtccgttggg atgccaagta
     1561 cgccacatgg gataacttca caggaaaacc ggtggatggg tatgaggtga atcgcatcat
     1621 cggcacaaag gccgtggcgt ttgctctgcg cgaggcacaa atccatgcgg ctgcgcttgg
     1681 ctatggcttg cttttatggg atggatatcg gccaagaact gcggtggact gcttcctgcg
     1741 ttgggcagcg caaccggagg acaatctcac aaaagaaaaa ttttacccca atatagagcg
     1801 agccgagttg attacaaagg gttatgtggc ctcacaatcc agccatagcc gtggaagcgc
     1861 aattgatctt acgctctacc acctggatac aggggaactt gtttcaatgg gaagtaactt
     1921 cgattttatg gacgaacggt cgcatcatac agcaaaaggg ataggggatg cagaggcaca
     1981 aaatcgaaga tgcttgcgta aaatcatgga aagcagcgga tttcagtctt atcgctttga
     2041 atggtggcac tataagttga ttgatgagcc ataccccgat acctatttta attttgccgt
     2101 ttcataatga aagtattggt tttgtatcag attttggatt tgataaaatc tatgctggtc
     2161 atggacaatc ttttactgga aagtggttaa agcatctttt gtaatacatt gcaaattata
     2221 gtattcaatc tgcccagcgg cagaaaagaa aaaaaccgct gttgggcaga cctttcccac
     2281 gcccattttg tattttgctg gcggcggttt tgagaaatca aggccgccgt tcttttctgg
     2341 cagcaaaagg tgtggcggcc cataggagga tgccgctatg ctgttttgct attgccatgc
     2401 tctaatccac ttccaccact caaaaaaagc cttgcccctc catgatgtgc accccaaaag
     2461 ttagactaga aatctaatta a
//
LOCUS       DACBYO010000317         2464 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.198, whole genome shotgun sequence.
ACCESSION   DACBYO010000317 DACBYO010000000
VERSION     DACBYO010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.198"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            270..1772
                     /locus_tag="IVD26_003166"
     CDS             270..1772
                     /locus_tag="IVD26_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAP6081039.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            1839..2366
                     /locus_tag="IVD26_003167"
     CDS             1839..2366
                     /locus_tag="IVD26_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP6081040.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
BASE COUNT          838 a          430 c          540 g          656 t
ORIGIN      
        1 ctcccgaagt agttgacaaa atcattttct ttatgctatc gtaatttcaa atataggaca
       61 aagtgaggga tccgtgcatt gaaaaattaa gtcgattgat gaaagctgca ttcagactgt
      121 accttgtgga gacaaggaag cagtgtgcag attttcggga ttggcttggt tttttcgatg
      181 tatgggtctt tttgtgtgta tccaaccctt gcatcctctt tagccagttc tgaaaatagg
      241 actggtcttt ttttacgagg tgatggaaaa tgtctaaaat cgaaataaaa aatctgacat
      301 tcggctacga cagccaaggc acattattat ttgaacaagc aaatctaaat tttgacacac
      361 aatggaaact aggacttatc ggacgaaacg gtcgaggaaa gacaacttta ctgaatattc
      421 tacaaaacaa actaccttat caagggcaag taatccatca gcaagaattt gcctatttcc
      481 cgcaacagac aaaagataaa gaacgtttaa cctattacgt gttaaatgat attacggatt
      541 ttgagatatg ggaaatcgaa agagagctcc aattgatgca aacagatcct gaaatcttat
      601 ggagagaatt cagcacacta tcggggggag agaagacaaa agtcctactg gcacttttat
      661 ttgtggatga cactcatttc ccgttaatcg atgaaccaac gaatcatttg gatatctctg
      721 gtagaaaaca agtagcggct tatttgaaaa agaaaaaaca aggcttcatc gtggtcagcc
      781 atgaccgggg atttatcgat gaagtagtgg accatgtttt agcaatcgaa aaaagtcaac
      841 tggaacttta tcaagggaat ttctctatct atgaagaaca gaaaaaactt cgtgatgaat
      901 ttgaaatggc tcaaaatgaa aaattgaaaa aagaagtcag taggctaaag aaaacagcag
      961 ctgaaaaagc cgaatggtct cgttcccgag aaggagataa aacaaagaaa caagtcggat
     1021 tcatcgatac tgaatctaga cgagtgaata aaggagcagt gggtgctgat gctgcacgga
     1081 cgatgaaacg atccaaagca atcgtgaatc ggatggagac ccagatcagc gagaaagaaa
     1141 aactattaaa agatatcgaa tatatcgatt ctttgacgat gaatagccaa gcgtctcacc
     1201 ataagcgact tttaagcgta gaagatcttc aattagggta tgaaaatctg ttattcgagc
     1261 caattcattt tacaatcgag cctcatcagc gggtggcgat ttcaggtcct aacggtgcag
     1321 gaaagtcatc cattatccat tatcttctgg gggcattcaa cggcaaggtt ataggagaaa
     1381 aataccagcc aaaacatctg agcattagtt atgcaagcca aaattatgaa gacaatcgag
     1441 gaacgttggc ggaatttgca gagaaaaacc aagtagacta ccaagcattt ttgaacaacc
     1501 tccgaaagct tgggatggaa agagatgttt ttcataacaa gatcgagcag atgagtatgg
     1561 gccaacggaa aaaagtggaa ttggctaaat ctttatcaca gccagctgaa ctatatacat
     1621 gggatgaacc attgaattat ttggatgtct tcaatcaaga acaattagaa caactgatct
     1681 tgaacgtgaa acctgccatg ttactagtgg aacatgatca aaccttcctg gataaagtat
     1741 ctactgagat tatttctctt gagagaatct aacccttgta atctcaagaa caacaaggta
     1801 tggttaaggg gaactttgcc aacgaaggag agaatcacat gctttatgta acgagacacg
     1861 gagaaacaac ttggaacgca caaggattag tttgcggacg ggcagatgtg ccgctgactg
     1921 aaaaaggaca gatgcaggca cagaaactag cagaaaaggt agtagatttg cctgttccaa
     1981 tcacgaaaat catccattcc cctcttcaac gagcaagaga tacagcacaa gcagttgctg
     2041 atcgtctcag cttgccgctg accgttgatg aacgattggt agaaatggat tttggggatt
     2101 atgatggact gccaagcaaa gatgagaact ttcaaaaagc acgtttagcg ttcgctgtac
     2161 gattcccaaa tggggagtca gtcttagatg tgtatgcacg gatcgttcct ttattgaaag
     2221 aatgcatcga agacgaagaa aatgtctatc tgttagtttg ccataatgcc ttgataagag
     2281 tgatcaatgc ttattttcat ccgatgccta atgaggggtt ctttacattc atggtagata
     2341 atacagaatt ggtttcttat gagtaattat gtttttgtgt tatttaaata aaatatttca
     2401 aggcactgct tttgcttagc agtgcctttt ttaggttatg acaattcttt tgataatata
     2461 aact
//
LOCUS       DACBYO010000318         2315 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.202, whole genome shotgun sequence.
ACCESSION   DACBYO010000318 DACBYO010000000
VERSION     DACBYO010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.202"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            <1..724
                     /locus_tag="IVD26_003168"
     CDS             <1..724
                     /locus_tag="IVD26_003168"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP6081041.1"
                     /translation="NKNHIWDEWAFERYIKSPDYNGPDMTDFGHRCLTDPEFNEEYKK
                     QSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFIDQIKQVIEAIKKTPDSR
                     RLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRSGDVFLGVPFNIASYALL
                     THLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIRAFPTLVLNQEKQSVFDF
                     EMEDIQLEGYDPHPAIKAPIAV"
     gene            744..1271
                     /locus_tag="IVD26_003169"
     CDS             744..1271
                     /locus_tag="IVD26_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP6081042.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(1334..1987)
                     /locus_tag="IVD26_003170"
     CDS             complement(1334..1987)
                     /locus_tag="IVD26_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP6081043.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            2119..>2315
                     /locus_tag="IVD26_003171"
     CDS             2119..>2315
                     /locus_tag="IVD26_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EDD domain protein"
                     /protein_id="HAP6081044.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPP"
BASE COUNT          807 a          435 c          463 g          610 t
ORIGIN      
        1 aaataaaaac catatttggg atgaatgggc atttgaacgc tacatcaaaa gtccagacta
       61 taatggacca gatatgactg attttggcca tagatgtttg acagatcctg aattcaatga
      121 agaatataaa aagcagagca agcttttttg cgagaagatc ctaaccgatg attcctttgc
      181 tgaaacatac ggcgatcttg gacacatcta cggctatcaa tggcgtcact gggaaacaaa
      241 agacggtggc tttatcgatc aaatcaaaca agtgatcgaa gcaatcaaaa agactcctga
      301 ttctagaaga ttgatcgttt ctgcatggaa tccggaagat gttcctagca tggctttgcc
      361 tccttgtcat acgatgtttc aattttatgt tcaagaggga cggctaagct gccaattgta
      421 tcaacgcagt ggggatgtgt ttctaggcgt tccgttcaac attgcaagtt atgcgttgct
      481 gactcaccta attgcacatg aaacaggttt agcggttggc gaatttgttc acacattagg
      541 agatgctcat ctttatatca atcatatcga acaaatgaaa gaacaattga gccgagaaat
      601 acgcgcattt ccgactttag ttttgaatca ggaaaagcag tcagtatttg attttgagat
      661 ggaagatatc caattagaag gatatgaccc acatccggcg atcaaagctc ctatcgctgt
      721 ttagaatcag aaaggatgag aaaatgttag ctgcaatttg ggcacaggat gaaaacggat
      781 tgattggaaa agaagaccgt cttccttggc gtttgccaaa tgatctgaaa ttcttcaaac
      841 aaatgacaga agcaaataca ctagtgatgg gacgaaaaac attcgaaggg atgggtagcc
      901 gtccgttgcc gaatcgtcag acgattgttt tgacgagaga ttcttcctat aaagcagaag
      961 gcgtgcatgt catgcatagt gtggaagacg tgcttgctct ggaaaaagaa acagacggta
     1021 tctttttcat cgctggaggg tcagctgttt atcaagaatt tctgccattt tgtacgatat
     1081 tataccgtac agtcatccat catgtattcg atggagatgc ttattttcca cctgttgact
     1141 ggtctgattg gtcactgatc aatactagtc aaggagaaat ggatgaaaaa aatcgttatc
     1201 cgcatcaatt tgaaacgtat cagcgtaatg agaatcctgt aaaaagcggg acaggcgaat
     1261 tgacgatata aaaaagctat ggatagacta gctgttattt agagctgtcc catccatagc
     1321 tttatttttt ttattaagta aagaataaaa cagagaagta cataaaacct gcacctaaca
     1381 taacaaacaa atgccaaaca acatgcatat agcggataga attcaagcta taaaagaatg
     1441 cgcctatcgt gtaagaaagc ccgcctgcta ccatcaaaat aacaccagtc attccaagag
     1501 agtgataaag aggaacagca gccacgacac agagccaccc cataaaaata tagatgatcg
     1561 tagatacttt tgatactctc tcccgtttat gcaacgtcaa cgctttatat ataatgccaa
     1621 gaatcgcaaa caaccagatt aatacaaata aagtccaacc tagccatcct cggatactca
     1681 gcaaacaaaa aggagtataa cttcctgcaa tcaaaagaaa aatcgaacta tgatcgaata
     1741 cttggaacac cttttttgct tttgtaaaaa tcaatgaatg aaacaaagta gacgttaaaa
     1801 ataaaagaat catcatcgat ccatagatag cataagagac aatatggagg gaggaatgca
     1861 agtgggcacc ttttactaaa agaaccacta gtcccgcgat actcaatcca gtcccaattc
     1921 catgggtgac tgcattaaac acttcattta atatttcata cgttcgatta aatttcgttt
     1981 tttccatgaa aacggctcct ttactaggtg taattaatga aaaatcatta tttgtctgtt
     2041 atactaaaaa tagaaattgt cttacatgta gtttaacatg aataaggcat cttgttaaag
     2101 aaagagagag agaaaataat gacaaatgta aaaatcgtaa cagattcttc atgtacgatg
     2161 gaaaaaaatg tacgcgatgc tttaggcatt cgtgtcatgc cgctatccat catgatcgac
     2221 ggaacagtat atcccgatga tgaccaacta gacggcgaaa gatttatgga aatgatggcg
     2281 aaagcaaaaa atctgcccaa aacaagccaa ccacc
//
LOCUS       DACBYO010000319         1266 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.239, whole genome shotgun sequence.
ACCESSION   DACBYO010000319 DACBYO010000000
VERSION     DACBYO010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.239"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            11..982
                     /locus_tag="IVD26_003172"
     CDS             11..982
                     /locus_tag="IVD26_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HAP6081045.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            975..>1266
                     /locus_tag="IVD26_003173"
     CDS             975..>1266
                     /locus_tag="IVD26_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HAP6081046.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVL"
BASE COUNT          339 a          270 c          361 g          296 t
ORIGIN      
        1 aggagaacca atgagaaaaa gtgtgggcat tactgttttt ggatgcgaac aggatgaggc
       61 aaatgctttc cgcgctttat cgccggattt tcatattatc cctacgctga ttagcgatgc
      121 gatatcggca gacaacgcaa aattggccgc tggcaatcaa tgcgttagcg taggccataa
      181 gtccgaggtt tccgaggcga caattcttgc gctgagaaag gtcggggtaa aatacatttc
      241 tacccgcagc atcggctgcg atcacattga tacgactgcc gccgagagaa tgggaatctc
      301 ggttggcacg gttgcgtatt cgccggacag cgttgcggat tatgctttga tgctgatgct
      361 gatggccata cggggtgcaa aacccaccat gcacgccgtg gcgcaacaag atttcagatt
      421 ggatcgtatc cgggggaaag aactggggga tatgactgtg ggagttattg gaaccggcca
      481 tatcgggcaa gcggtcgtca aaaggctgcg gggatttgga tgccatgtgc tggcctatga
      541 taacagccga aaaatggatg cagattatgt ccagcttgat gagcttctaa aaaacagcga
      601 tattgttacg ctccatgtgc cgctttgtgc ggatacccgc catctgatcg gtcagaagca
      661 aattggagag atgaagcaag gcgcattttt aatcaacacc gggcgcggag cgcttgtcga
      721 taccggggcg ctggtggagg cgttggaaag cggaaagctg ggtggtgcgg cactggatgt
      781 gttggagggc gaggatcagt ttgtttatac cgattgctcg cagaaagtgc ttgaccatcc
      841 ctttttgtcg cagcttttaa ggatgccgaa tgtgatcatc acaccccata cggcgtacta
      901 cactgagcgt gtgctgcagg atactacaga aaaaacaatc aggaattgtc tcaattttga
      961 aaggagttta cagcatgaat agaataaaag tcgcaatcat cttcggcggt tgctcggagg
     1021 aacatgatgt gtcggtaaaa tccgcaatag aaattgctgc gaacattgat acggaaaaat
     1081 tcgatccgca ctacatcgga attacaaaaa acggtgtatg gaagctatgc aagaagccat
     1141 gtacggaatg ggaagccgac agtctccccg ccatactctc cccggatagg aaaacgcatg
     1201 ggctgcttgt catgaaagaa agcgaatacg aaacacggcg tattgatgtg gctttcccgg
     1261 ttttgc
//
LOCUS       DACBYO010000320         1158 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.245, whole genome shotgun sequence.
ACCESSION   DACBYO010000320 DACBYO010000000
VERSION     DACBYO010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.245"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            545..1093
                     /gene="aac(6')"
                     /locus_tag="IVD26_003174"
     CDS             545..1093
                     /gene="aac(6')"
                     /locus_tag="IVD26_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAP6081047.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          413 a          169 c          232 g          344 t
ORIGIN      
        1 tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag tgatcgatct gactgcggct
       61 gtagatggag tagaggtgaa cctaagacag gataagtgat gaataaggtg gcatgaacac
      121 cttgaaatca tcaataagta tcctaaaaac gaacaagtac aaaaacattg aaaacgacaa
      181 taatgaattt ttgttcctct tagtatttct accgattccc tttgcttttt tgtaattatc
      241 taaaaattct aaaaattaag attattatat gaaaacaggt tttatttgtc aattcataat
      301 tggttttttt taaagcaaaa gataatctat atcatgatga acaaacagag ttttttcctc
      361 caattgatgg ctttcctgat ctttcctatt ttgaataaag tgtttctgta taatttttta
      421 ttttataagt aagataaata atgaaagaat agagatactg attggtagct aaagattttt
      481 gagcgagaac atttcgtttt ttcaaaagga ctgttagaat aagcaagaac aagggggaag
      541 acgtatgata atcagtgaat ttgaccgtaa taatccagta ttgaaagatc agctttctga
      601 tttactgaga ctgacttggc cggaagaata tggagacagc tcggcagaag aagtagaaga
      661 aatgatgaat ccagaacgaa tcgcggtagc agcggtagac caagatgagt tagtaggatt
      721 tattggtgca atccctcaat acggtatcac aggttgggaa ttgcatccat tagttgtaga
      781 aagctcccga cgaaagaacc aaataggtac tcgattagtc aattacttag aaaaagaagt
      841 agcttccaga ggaggaatca cgatttattt aggtacggat gatttagacc atggaacaac
      901 gttaagtcaa acggacctgt atgagcatac atttgataaa gtggcttcca tccagaacct
      961 tcgtgaacat ccgtatgaat tctatgaaaa attaggttat aaaatcgtag gtgtcttacc
     1021 aaatgcaaat ggctgggaca aaccggatat ttggatggca aaaacgatta ttcctcgacc
     1081 aaattctcaa taataaaaag aggttgtgac agaagtaatc agcttcaaga aataagaagg
     1141 aatttacgaa aattactt
//
LOCUS       DACBYO010000321         1018 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.251, whole genome shotgun sequence.
ACCESSION   DACBYO010000321 DACBYO010000000
VERSION     DACBYO010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1018
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.251"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            176..983
                     /gene="vanY"
                     /locus_tag="IVD26_003175"
                     /pseudo
     CDS             176..983
                     /gene="vanY"
                     /locus_tag="IVD26_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-B/VanY-G family D-Ala-D-Ala
                     carboxypeptidase"
BASE COUNT          316 a          216 c          251 g          235 t
ORIGIN      
        1 tcaattctga ttcatcagtc ccataaatta tagagccgta taaccctgcc ggtctttttt
       61 tgctgctaca ggaaaactac agactggcta cagggaaagt acagatgcgc ttgccataat
      121 aacaatcgta ccagccacaa atcgtagttt tattgcaaag gaggcattcg atcaaatgga
      181 aaaaagcaac tatcattcca atgcggatca tcacaaacgg catatgaaac aatccgtgga
      241 aaagcgggct tttctatgtg cgttcattat ttcgttcaca gtctgcacgc tgtttttggg
      301 ggcggagact ggcttccgta ttggaggcaa cacagatacc gcccatccct gcaactcata
      361 caggcagcag cactgacgta gtggagaatt tggaggaaaa cgctcttgcc accgccaaag
      421 aacagggaga tgaacaggaa tggagcctga ttttagtgaa caggcagaac cccatccccg
      481 cacagtacga tgtggagctt gagcaactat caaatggtga gcggatagat attcggattt
      541 ctccctatct tcaagatttg tttgatgccg caagaactga tggagtttac ccgattgtcg
      601 catccggata ccgaacaaca gaaaaacagc aagaaattat ggatgaaaaa attgccgaat
      661 ataaggcgaa aggctacacc tctgcacagg ctaaagcgga agcagaaact tgggtggccg
      721 tgccgggaac gagcgagcat cagcttggtc ttgctgtgga tatcaatgcg gacggaattc
      781 attcaacagg caacgaggtt tatagatggc tggatgaaaa cagctatcgt tttggtttta
      841 ttcgtcgcta cccaccagac aagacagaga taaccggtgt gagcaacgag ccgtggcatt
      901 accgatatgt tggcatcgaa gctgccacag agatgtacaa ccaaggggtt tgccttgagg
      961 aatatttaaa accagaaaaa tgagaaaagg atgttatgtt atggacagaa aaagattg
//
LOCUS       DACBYO010000322          999 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.254, whole genome shotgun sequence.
ACCESSION   DACBYO010000322 DACBYO010000000
VERSION     DACBYO010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.254"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            267..>999
                     /gene="aph(2'')-I"
                     /locus_tag="IVD26_003176"
     CDS             267..>999
                     /gene="aph(2'')-I"
                     /locus_tag="IVD26_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="HAP6081048.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFGEDILRMYGNI"
BASE COUNT          415 a           81 c          167 g          336 t
ORIGIN      
        1 agggatttta ttctttattt aaaactttgc aacagaaccg tacaagatat attaaattga
       61 tttttgaatt tttgaaaaaa gaaagaaatg ctaatgcagt tattttagac cctcataaaa
      121 ataatccaag agcaataagg gcataccaaa aatctggttt tagaattatt gaagatttgc
      181 cagaacatga attacacgag ggcaaaaaag aagattgtta tttaatggaa tatagatatg
      241 atgataatgc cacaaatgtt aaggcaatga aatatttaat tgagcattac tttgataatt
      301 tcaaagtaga tagtattgaa ataatcggta gtggttatga tagtgtggca tatttagtta
      361 ataatgaata catttttaaa acaaaattta gtactaataa gaaaaaaggt tatgcaaaag
      421 aaaaagcaat atataatttt ttaaatacaa atttagaaac taatgtaaaa attcctaata
      481 ttgaatattc gtatattagt gatgaattat ctatactagg ttataaagaa attaaaggaa
      541 cttttttaac accagaaatt tattctacta tgtcagaaga agaacaaaat ttgttaaaac
      601 gagatattgc cagtttttta agacaaatgc acggtttaga ttatacagat attagtgaat
      661 gtactattga taataaacaa aatgtattag aagagtatat attgttgcgt gaaactattt
      721 ataatgattt aactgatata gaaaaagatt atatagaaag ttttatggaa agactaaatg
      781 caacaacagt ttttgagggt aaaaagtgtt tatgccataa tgattttagt tgtaatcatc
      841 tattgttaga tggcaataat agattaactg gaataattga ttttggagat tctggaatta
      901 tagatgaata ttgtgatttt atatacttac ttgaagatag tgaagaagaa ataggaacaa
      961 attttggaga agatatatta agaatgtatg gaaatatag
//
LOCUS       DACBYO010000323          876 bp    DNA     linear   BCT 10-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW15522
            SAMN16604469-rid10965433.guided.259, whole genome shotgun sequence.
ACCESSION   DACBYO010000323 DACBYO010000000
VERSION     DACBYO010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN16604469
            Sequence Read Archive: SRR12963034
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000879614.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000879614.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2020 01:56:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,032
            CDSs (with protein)               :: 3,032
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 37 of 83
            Pseudo Genes (incomplete)         :: 35 of 83
            Pseudo Genes (internal stop)      :: 19 of 83
            Pseudo Genes (multiple problems)  :: 7 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN16604469-rid10965433.guided.259"
                     /isolate="UW15522"
                     /isolation_source="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2015"
                     /collected_by="University Hospital Frankfurt"
     gene            23..850
                     /gene="vanW"
                     /locus_tag="IVD26_003177"
     CDS             23..850
                     /gene="vanW"
                     /locus_tag="IVD26_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HAP6081049.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGEPFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
BASE COUNT          272 a          175 c          219 g          210 t
ORIGIN      
        1 aatgagaaaa ggatgttatg ttatggacag aaaaagattg acacagcgtt tcccgttcct
       61 gcttccaatg agacgggcgc agagaaaaat gtgcttttat gcgggaatga gatttgacgg
      121 ctgtcgctat gcgcagacga taggggaaaa atcgctttcc catttgctct ttgaaacgga
      181 ttgcgcatta tacaaccaca ataccggatt tgacatgata taccaggaaa acaaggtgtt
      241 caacttaaag ctggcagcaa agaccttaaa cggcttattg ataagaccgg gggaaccctt
      301 ttctttctgg tggctggtac gccatgcgga caaagatacc ccctataaag acggccttac
      361 ggtgaccaat ggtaaactca ccaccatgtc gggcggcggt atgtgccaga tgagcaattt
      421 actattttgg atgttcctgc atacgccatt gacaattatc cagcgcagag gtcacgaagt
      481 aaaggagttt ccagagccaa acagtgacga gattaaaggg gtggatgcaa ccatttcaga
      541 gggctggatt gatttaaaag tgcgaaacga taccgactgc acctaccaaa tatgggtgac
      601 cttagatgat gagaaaatca tcggtcaggt gtccgccgac aaagagcccc aagcattata
      661 caaaattaca aatggcagta tccagtatgt ccgtgaaagt ggcgggattt atgaatatgc
      721 ccaggttaaa cggatgcaag ttgccttagg taccggggaa ataatagatt gcaagctgct
      781 ttatacaaac aaatgcaaaa tctgttatcc cctcccggaa agtgtggata ttcaggagga
      841 gaaccaatga gaaaaagtgt gggcattact gttttt
//
